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34,719,415
Effect of the course of treatment with broad-spectrum antibiotics on intestinal flora and short-chain fatty acids in feces of very low birth weight infants: a prospective study.
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
Zhongguo Dang Dai Er Ke Za Zhi
23
10
10.7499/j.issn.1008-8830.2107103
eng
2,021
10
15
null
null
null
[OBJECTIVES] To study the effect of the course of treatment with broad-spectrum antibiotics on intestinal flora and short-chain fatty acids (SCFAs) in feces of very low birth weight (VLBW) infants. [METHODS] A total of 29 VLBW infants who were admitted to the Neonatal Diagnosis and Treatment Center of Children's Hospit...
Broad-spectrum antibiotics; Intestinal flora; Short-chain fatty acid; Very low birth weight infant
null
null
null
null
null
34,719,308
Influential factors for access to and participation in rehabilitation for people with lower limb amputation in East, South, and Southeast Asian developing countries: a scoping review.
Disability and rehabilitation
Disabil Rehabil
44
25
10.1080/09638288.2021.1994025
eng
2,022
12
null
2,021
10
31
[PURPOSE] To explore factors impacting access to and participation in rehabilitation for people with lower limb amputation (LLA) in East, South, and Southeast Asian developing countries. [MATERIALS AND METHODS] A scoping review was undertaken following the PRISMA-ScR guidelines. Five electronic databases (PsycINFO (Ovi...
Access; Asian developing countries; amputation; participation; rehabilitation
0.762
140
Rehabilitation
Medicine
2,022
34,719,275
Pelvic incidence is not associated with the development of hip osteoarthritis.
The bone joint journal
Bone Joint J
103-B
11
10.1302/0301-620X.103B11.BJJ-2021-0472.R1
eng
2,021
11
null
null
null
null
[AIMS] Pelvic incidence (PI) is considered an important anatomical parameter for determining the sagittal balance of the spine. The contribution of an abnormal PI to hip osteoarthritis (OA) remains controversial. In this study, we aimed to investigate the relationship between PI and hip OA, and the difference in PI bet...
Acetabular centre edge angle; Hip; Hip osteoarthritis; Hip-spine relationship; Pelvic incidence; Sagittal femoral head coverage; anterior centre edge angles; centre edge angles; developmental dysplasia of the hip (DDH); femoral head; hip disorders; hip osteoarthritis (OA); pelvic incidence; primary OA; spine
null
null
null
null
null
34,718,702
Newborn Outcomes Among Veterans Utilizing VHA Maternity Benefits, 2016-2020.
Military medicine
Mil Med
188
5-6
10.1093/milmed/usab457
eng
2,023
5
16
null
null
null
[INTRODUCTION] Public Law 111-163 Section 206 of the Caregivers and Veteran Omnibus Health Services Act amended the Veterans Health Administration's (VHA) medical benefits package to include 7 days of medical care for newborns delivered by Veterans. We examined the newborn outcomes among a cohort of women Veterans rece...
null
0.5
83
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,023
34,718,486
Predictors of cognitive dysfunction after cardiac surgery: a systematic review.
European journal of cardiovascular nursing
Eur J Cardiovasc Nurs
21
3
10.1093/eurjcn/zvab086
eng
2,022
4
9
null
null
null
[AIMS] Postoperative cognitive dysfunction (POCD) is often experienced by cardiac surgery patients; however, it is not known if some groups of patients experience this more frequently or severely than others.The aim of this systematic review was to identify preoperative and postoperative predictors of cognitive dysfunc...
Cardiac surgical procedures; Cognitive dysfunction; Predictor
0.851
66
Advanced and Specialized Nursing; Medical and Surgical Nursing; Cardiology and Cardiovascular Medicine; Medicine
Medicine; Nursing
2,022
34,718,357
An evaluation of a national mass media campaign to raise public awareness of possible lung cancer symptoms in England in 2016 and 2017.
British journal of cancer
Br J Cancer
126
2
10.1038/s41416-021-01573-w
eng
2,022
2
null
2,021
10
30
[BACKGROUND] A two-phase 'respiratory symptoms' mass media campaign was conducted in 2016 and 2017 in England raising awareness of cough and worsening shortness of breath as symptoms warranting a general practitioner (GP) visit. [METHOD] A prospectively planned pre-post evaluation was done using routinely collected dat...
null
2.867
281
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,717,922
miR-338-5p Levels and Cigarette Smoking are Associated With Neuropathic Pain Severity in Individuals With Spinal Cord Injury: Preliminary Findings From a Genome-Wide microRNA Expression Profiling Screen.
Archives of physical medicine and rehabilitation
Arch Phys Med Rehabil
103
4
10.1016/j.apmr.2021.09.005
eng
2,022
4
null
2,021
10
27
[OBJECTIVE] To identify microRNA biomarkers and clinical factors associated with neuropathic pain after spinal cord injury. [DESIGN] Cross-sectional, secondary analysis of baseline data collected from ongoing clinical studies. Using a genome-wide microRNA screening approach, we studied differential microRNA expression ...
MicroRNAs; Neuralgia; Rehabilitation; Smoking; Spinal cord injuries; Tobacco products
1.062
225
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science
Health Professions; Medicine
2,022
34,717,902
The Impact of an Inpatient Pancreatitis Service and Educational Intervention Program on the Outcome of Acute Pancreatitis.
The American journal of medicine
Am J Med
135
3
10.1016/j.amjmed.2021.09.021
eng
2,022
3
null
2,021
10
27
[BACKGROUND] We introduced an inpatient pancreatitis consultative service aimed to 1) provide guideline-based recommendations to acute pancreatitis inpatients and 2) educate inpatient teams on best practices for acute pancreatitis management. We assessed the impact of pancreatitis service on acute pancreatitis outcomes...
Acute pancreatitis; Educational intervention; Enteral nutrition; Length of hospitalization; Subspeciality care
0.991
262
Medicine
Medicine
2,022
34,717,640
Dysregulation of the miR-30a/BiP axis by cigarette smoking accelerates oral cancer progression.
Cancer cell international
Cancer Cell Int
21
1
10.1186/s12935-021-02276-1
eng
2,021
10
30
2,021
10
30
[BACKGROUND] Cigarette smoking is the most significant cause of oral cancer progression. Cigarette smoke condensate (CSC) has been shown to induce endoplasmic reticulum (ER) stress. Binding immunoglobulin protein (BiP) being as an ER stress regulator, has been reported to be implicated in malignant behaviors. Therefore...
Chaperons; Cigarette smoking; Oral squamous cell carcinoma; Vascular endothelial growth factor; miRNA
1.099
90
Cancer Research; Genetics; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,717,592
Mediating effect of the parent-child relationship on the association between parenting stress and children's eating behaviors.
BMC public health
BMC Public Health
21
1
10.1186/s12889-021-12052-5
eng
2,021
10
30
2,021
10
30
[BACKGROUND] Emerging evidence suggests that parenting stress plays a significant role in children's eating behavior. However, the nature of the relationship between parenting stress and children's health behaviors is still not well understood, possibly because there is limited understanding of the mediating factors. T...
Child eating behaviors; Parenting stress
1.156
211
Public Health, Environmental and Occupational Health
Medicine
2,021
34,717,537
Phenotypic variation of floral organs in flowering crabapples and its taxonomic significance.
BMC plant biology
BMC Plant Biol
21
1
10.1186/s12870-021-03227-8
eng
2,021
10
30
2,021
10
30
[BACKGROUND] In angiosperms, phenotypic variation of floral organs is often considered as the traditional basis for the evolutionary relationship of different taxonomic groups above the species level. However, little is known about that at or below the species level. Here, we experimentally tested the phenotypic variat...
Ancestor-inclined distribution; Floral organ phenotype; Flowering crabapple; Numerical taxonomy; Phenotypic variation; Taxonomic significance
1.117
159
Plant Science
Agricultural and Biological Sciences
2,021
34,717,527
Short-term immune response after inactivated SARS-CoV-2 (CoronaVac®, Sinovac) and ChAdOx1 nCoV-19 (Vaxzevria®, Oxford-AstraZeneca) vaccinations in health care workers.
Asian Pacific journal of allergy and immunology
Asian Pac J Allergy Immunol
40
3
10.12932/AP-250721-1197
eng
2,022
9
null
null
null
null
[BACKGROUND] Inactivated SARS-CoV-2 (CoronaVac®, Sinovac, or SV) and ChAdOx1 nCoV-19 (Vaxzevria®, Oxford-Astra Zeneca, or AZ) vaccines have been administered to the health care workers (HCWs). [OBJECTIVE] To determine the short-term immune response after the SV and AZ vaccinations in HCWs. [METHODS] In this prospective...
null
0.845
43
Immunology and Allergy; Medicine; Immunology
Immunology and Microbiology; Medicine
2,022
34,717,258
Privileged background protects against drug charges: A long-term population-based longitudinal study.
The International journal on drug policy
Int J Drug Policy
100
null
10.1016/j.drugpo.2021.103491
eng
2,022
2
null
2,021
10
27
[BACKGROUND] We investigated the importance of indicators of parental socio-economic status (SES) for getting an official drug charge, while we controlled for self-reported drug law infractions (use of illegal drugs and/or drug trafficking) and potential variables confounding the association. [METHODS] We used data fro...
Drug charges; Drug policy; Longitudinal; Population; Socioeconomic status
null
null
null
null
null
34,717,183
Long-term air pollution, noise, and structural measures of the Default Mode Network in the brain: Results from the 1000BRAINS cohort.
International journal of hygiene and environmental health
Int J Hyg Environ Health
239
null
10.1016/j.ijheh.2021.113867
eng
2,022
1
null
2,021
10
28
[BACKGROUND] While evidence suggests that long-term air pollution (AP) and noise may adversely affect cognitive function, little is known about whether environmental exposures also promote structural changes in underlying brain networks. We therefore investigated the associations between AP, traffic noise, and structur...
Air pollution; Brain imaging; Brain structure; Cognitive function; Particulate matter
1.47
126
Public Health, Environmental and Occupational Health
Medicine
2,022
34,717,179
Governing health data across changing contexts: A focus group study of citizen's views in England, Iceland, and Sweden.
International journal of medical informatics
Int J Med Inform
156
null
10.1016/j.ijmedinf.2021.104623
eng
2,021
12
null
2,021
10
21
[BACKGROUND] The governance structures associated with health data are evolving in response to advances in digital technologies that enable new ways of capturing, using, and sharing different types of data. Increasingly, health data moves between different contexts such as from healthcare to research, or to commerce an...
Data governance; Data privacy; Data sharing; Health data; Public attitudes; Public trust
1.135
141
Health Informatics
Medicine
2,021
34,716,986
Outcomes of radical surgical resections for nonmetastatic anorectal melanomas: Experience from a tertiary care centre.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Colorectal Dis
23
12
10.1111/codi.15975
eng
2,021
12
null
2,021
11
16
[AIM] The outcome of radical surgery in nonmetastatic anorectal melanoma (AM) patients is studied infrequently. Here, we aimed to explore the stage-wise outcomes and the impact of radical resections in these patients. [METHODS] In this single-centre retrospective study, data of 154 eligible patients were recorded and a...
anorectal melanoma; melanoma lymphadenectomy; melanoma surgery; mucosal melanoma
0.925
110
Gastroenterology
Medicine
2,021
34,716,912
Associations of pre-pandemic levels of physical function and physical activity with COVID-19-like symptoms during the outbreak.
Aging clinical and experimental research
Aging Clin Exp Res
34
1
10.1007/s40520-021-02006-7
eng
2,022
1
null
2,021
10
30
[BACKGROUND] One's physical function and physical activity levels can predispose or protect from the development of respiratory infections. We aimed to explore the associations between pre-pandemic levels of physical function and physical activity and the development of COVID-19-like symptoms in Swedish older adults. [...
Coronavirus disease 2019; Mobility; Muscle strength; Older adults; Physical activity
0.982
95
Aging; Geriatrics and Gerontology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,716,784
Electroconvulsive seizure inhibits the mTOR signaling pathway via AMPK in the rat frontal cortex.
Psychopharmacology
Psychopharmacology (Berl)
239
2
10.1007/s00213-021-06015-2
eng
2,022
2
null
2,021
10
30
[RATIONALE] Accumulating evidence indicates critical involvement of mammalian target of rapamycin (mTOR) in the treatment of depressive disorders, epilepsy, and neurodegenerative disorders through its signal transduction mechanisms related to protein translation, autophagy, and synaptic remodeling. Electroconvulsive se...
AMP-activated protein kinase; Electroconvulsive therapy; Mammalian target of rapamycin
1.05
218
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,022
34,715,781
Extracellular matrix alterations in the skin of patients affected by psoriasis.
BMC molecular and cell biology
BMC Mol Cell Biol
22
1
10.1186/s12860-021-00395-1
eng
2,021
10
29
2,021
10
29
[BACKGROUND] Psoriasis is a chronic inflammatory disease dependent upon a complex interaction between genetic predisposition and immunological factors. It is characterized by skin lesions throughout the body, causing great morbidity and affecting life quality. The present study aimed to evaluate the protein and mRNA ex...
Heparanase; Heparanase-2; Metalloproteinases; Psoriasis; Syndecan-1; TIMP2
null
null
null
null
null
34,715,774
Technical challenges regarding the use of formalin-fixed paraffin embedded (FFPE) tissue specimens for the detection of bacterial alterations in colorectal cancer.
BMC microbiology
BMC Microbiol
21
1
10.1186/s12866-021-02359-z
eng
2,021
10
29
2,021
10
29
[BACKGROUND] Formalin-fixed paraffin embedded (FFPE) tissues may provide an exciting resource to study microbial associations in human disease, but the use of these low biomass specimens remains challenging. We aimed to reduce unintentional bacterial interference in molecular analysis of FFPE tissues and investigated t...
Colorectal neoplasms; DNA contamination; Formalin-fixed paraffin embedded; Gastrointestinal microbiome; High-throughput nucleotide sequencing; Low biomass
0.916
147
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,021
34,715,523
Effect of Primary Prophylactic Antiseizure Medication for Seizure Prevention Following Intracerebral Hemorrhage in the ERICH Study.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
31
1
10.1016/j.jstrokecerebrovasdis.2021.106143
eng
2,022
1
null
2,021
10
26
[OBJECTIVES] Intracerebral hemorrhage (ICH) has the highest morbidity and mortality rate of any stroke subtype and clinicians often administer prophylactic antiseizure medications (ASMs) as a means of preventing post-stroke seizures, particularly following lobar ICH. However, evidence for ASM efficacy in preventing sei...
Antiseizure medicine; Intracerebral hemorrhage; Prospective cohort study; Seizure; Stroke; outcome
0.713
85
Rehabilitation; Surgery; Cardiology and Cardiovascular Medicine; Neurology
Medicine
2,022
34,715,486
The effectiveness of the combined transcranial direct current stimulation (tDCS) and tailor-made notched music training (TMNMT) on psychoacoustic, psychometric, and cognitive indices of tinnitus patients.
American journal of otolaryngology
Am J Otolaryngol
43
1
10.1016/j.amjoto.2021.103274
eng
2,022
null
null
2,021
10
20
[PURPOSE] Tinnitus network(s) consists of pathways in the auditory cortex, frontal cortex, and the limbic system. The cortical hyperactivity caused by tinnitus may be suppressed by neuromodulation techniques. Due to the lack of definitive treatment for tinnitus and limited usefulness of the individual methods, in this ...
Cognitive functions; Tailor-made notched music training; Tinnitus; Transcranial direct current stimulation
null
null
null
null
null
34,715,188
Bipolar disorder and medical comorbidities: A Portuguese population-based observational retrospective study (2008-2015).
Journal of affective disorders
J Affect Disord
298
Pt A
10.1016/j.jad.2021.10.090
eng
2,022
2
1
2,021
10
29
[BACKGROUND] This study aimed to use the Charlson Comorbidity Index (CCI) to assess the prevalence of medical comorbidities among hospitalization episodes with a primary Bipolar Disorder (BD) diagnosis, and to analyze its association with hospitalization outcomes. [METHODS] A population-based observational retrospectiv...
Bipolar disorder; Charlson Comorbidity Index; Comorbidity; Hospital administrative data; Hospitalization; International Classification of Diseases
1.988
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
34,715,169
Adverse childhood experiences exacerbate the association between day-to-day discrimination and mental health symptomatology in undergraduate students.
Journal of affective disorders
J Affect Disord
297
null
10.1016/j.jad.2021.10.058
eng
2,022
1
15
2,021
10
26
[BACKGROUND] Adverse childhood experiences (ACEs) and day-to-day discrimination (hereafter, "discrimination") both contribute to mental health symptomatology in young adulthood, but how these constructs interact and whether they are associated with mental health remains unclear. This study evaluated whether the relatio...
Adverse childhood experiences; Discrimination; Mental health symptoms; Undergraduate college students; Young adults
1.988
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
34,714,541
Efficacy and safety of intrathecal morphine in total knee arthroplasty: A systematic review and meta-analysis.
Journal of opioid management
J Opioid Manag
17
5
10.5055/jom.2021.0674
eng
2,021
null
null
null
null
null
[OBJECTIVE] Morphine is a potent analgesic used to manage the pain following total knee arthroplasty (TKA). We aim to assess the safety and efficacy of intrathecal morphine (ITM) compared with placebo following TKA. [METHODS] We systematically searched four databases for trials that study the safety and efficacy of ITM...
null
null
null
null
null
null
34,714,430
Visceral obesity is a predictor of surgical site occurrence and hernia recurrence after open abdominal wall reconstruction.
Hernia : the journal of hernias and abdominal wall surgery
Hernia
26
1
10.1007/s10029-021-02522-5
eng
2,022
2
null
2,021
10
29
[PURPOSE] High body mass index (BMI) increases the risk of postoperative complications and hernia recurrence after abdominal wall reconstruction (AWR). However, BMI does not provide specific information on the mass and distribution of adipose tissue. We hypothesized that visceral fat volume (VFV) was a better predictor...
Abdominal wall reconstruction; Component separation; Incisional hernia recurrence; Visceral fat volume
0.925
89
Surgery
Medicine
2,022
34,714,194
Serum uric acid change in relation to antihypertensive therapy with the dihydropyridine calcium channel blockers.
Blood pressure
Blood Press
30
6
10.1080/08037051.2021.1996220
eng
2,021
12
null
2,021
10
29
[PURPOSE] We investigated serum uric acid changes in relation to the achieved clinic and ambulatory blood pressure after 8 weeks of antihypertensive therapy with two dihydropyridine calcium channel blockers. [MATERIALS AND METHODS] The study participants were patients with clinic and ambulatory hypertension, enrolled i...
Serum uric acid; ambulatory blood pressure; antihypertensive therapy; clinic blood pressure; dihydropyridine calcium channel blocker
0.397
58
Cardiology and Cardiovascular Medicine; Internal Medicine; Medicine
Medicine
2,021
34,713,832
Ginseng adjuvant therapy on COVID-19: A protocol for systematic review and meta-analysis.
Medicine
Medicine (Baltimore)
100
43
10.1097/MD.0000000000027586
eng
2,021
10
29
null
null
null
[BACKGROUND] Corona virus disease 2019 (COVID-19) is spreading fast and it brings great pressure to the social economy. Many reports revealed that ginseng can develop immunity for respiratory disease, but there is no evidence to prove its effects on COVID-19. This protocol of systematic review and meta-analysis will cl...
null
null
null
null
null
null
34,713,488
Effects of autophagy inhibition by chloroquine on hepatic stellate cell activation in CCl4-induced acute liver injury mouse model.
Journal of gastroenterology and hepatology
J Gastroenterol Hepatol
37
1
10.1111/jgh.15726
eng
2,022
1
null
2,021
11
9
[BACKGROUND AND AIM] Hepatic stellate cells (HSCs) activation, a critical event in liver fibrosis, has been recently shown to be related to autophagy. Determine whether chloroquine (CQ) could affect (i) the activation of HSC in vivo and (ii) the hepatic damage in a mice acute liver injury model. [METHODS] The acute liv...
Acute liver injury; Autophagy; Chloroquine; Hepatic stellate cell
1.067
156
Gastroenterology; Hepatology
Medicine
2,022
34,712,940
Measuring True Change in Individual Patients: Reliable Change Indices of Cardiac Rehabilitation Outcomes, and Implications for Quality Indicators.
CJC open
CJC Open
3
9
10.1016/j.cjco.2021.05.006
eng
2,021
9
null
2,021
5
16
[BACKGROUND] Mediated by outcomes such as improved exercise capacity, cardiac rehabilitation (CR) reduces morbidity and mortality. For accuracy, an individual CR patient's change must be measured reliably, an issue not typically considered in practice. Drawing from psychometric theory, we calculated reliable change ind...
null
0.59
23
Cardiology and Cardiovascular Medicine
Medicine
2,021
34,712,337
Relationships between physical characteristics and biomechanics of lower extremity during the squat.
Journal of exercise science and fitness
J Exerc Sci Fit
19
4
10.1016/j.jesf.2021.09.002
eng
2,021
10
null
2,021
10
4
[BACKGROUND/OBJECTIVE] There is a lack of information about relationship between physical characteristics and biomechanics of the lower extremity during the squat. Additionally, studies did not examine sex-related differences. The purpose of this study was to investigate relationships between physical characteristics a...
Joint flexibility; Motion analysis; Resistance exercise
0.772
35
Pharmaceutical Science; Pharmacology; Physical Therapy, Sports Therapy and Rehabilitation; Public Health, Environmental and Occupational Health; Sports Science
Health Professions; Medicine; Nursing; Pharmacology, Toxicology and Pharmaceutics
2,021
34,712,230
Effect of Immune Checkpoint Blockade on Myeloid-Derived Suppressor Cell Populations in Patients With Melanoma.
Frontiers in immunology
Front Immunol
12
null
10.3389/fimmu.2021.740890
eng
2,021
null
null
2,021
10
12
[INTRODUCTION] Myeloid-derived suppressor cells (MDSC) are a subset of immature myeloid cells that inhibit anti-tumor immunity and contribute to immune therapy resistance. MDSC populations were measured in melanoma patients receiving immune checkpoint inhibitors (ICI). [METHODS] Patients with melanoma (n=128) provided ...
MDSC; granulocytic MDSC; immune checkpoint blockade; melanoma; monocytic MDSC; nivolumab; pembrolizumab
2.331
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,021
34,711,793
State firearm laws and nonfatal firearm injury-related inpatient hospitalizations: A nationwide panel study.
The journal of trauma and acute care surgery
J Trauma Acute Care Surg
92
3
10.1097/TA.0000000000003445
eng
2,022
3
1
null
null
null
[BACKGROUND] Firearm injury remains a major cause of morbidity and mortality in the United States. Because of prior lack of comprehensive data sources, there is a paucity of literature on nonfatal firearm injury. Associations have previously been shown between state-level firearm laws and firearm fatalities, but few st...
null
1.11
217
Critical Care and Intensive Care Medicine; Surgery
Medicine
2,022
34,711,737
Telemedicine and visit completion among people with HIV during the coronavirus disease 2019 pandemic compared with prepandemic.
AIDS (London, England)
AIDS
36
3
10.1097/QAD.0000000000003119
eng
2,022
3
1
null
null
null
[OBJECTIVES] Telemedicine became the primary mode of delivering care during the COVID-19 pandemic. We describe the impact of telemedicine on access to care for people with HIV (PWH) by comparing the proportion of PWH engaged in care prior to and during the COVID-19 pandemic. [DESIGN AND METHODS] We conducted an observa...
null
1.26
233
Infectious Diseases; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
34,711,362
Cost-Effectiveness of Magnetic Resonance Imaging-Guided Thrombolysis for Patients With Stroke With Unknown Time of Onset.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
Value Health
24
11
10.1016/j.jval.2021.05.005
eng
2,021
11
null
2,021
7
31
[OBJECTIVES] Patients waking up with stroke symptoms are often excluded from intravenous thrombolysis with alteplase (IV-tpa). The WAKE-UP trial, a European multicenter randomized controlled trial, proved the clinical effectiveness of magnetic resonance imaging-guided IV-tpa for these patients. This analysis aimed to a...
cost-effectiveness; magnetic resonance imaging; quality-adjusted life-year; thrombolysis; tissue-type plasminogen activator
1.472
138
Health Policy; Medicine; Public Health, Environmental and Occupational Health
Medicine
2,021
34,711,168
Impact of maternal age on obstetric and neonatal morbidity: a retrospective cohort study.
BMC pregnancy and childbirth
BMC Pregnancy Childbirth
21
1
10.1186/s12884-021-04177-7
eng
2,021
10
28
2,021
10
28
[BACKGROUND] Pregnancies in women over 35 years of age are becoming more frequent. The majority of studies point to an age of 35 as a provider of obstetric and neonatal complications. But several confounding factors are not taken into account and this results in contradictory results. [METHODS] The objective was to qua...
Advanced maternal age pregnancies; Age; Neonatal morbidity; Obstetric morbidity
0.96
122
Obstetrics and Gynecology
Medicine
2,021
34,764,637
Efficacy of Pre-Treatment with Remimazolam on Prevention of Propofol-Induced Injection Pain in Patients Undergoing Abortion or Curettage: A Prospective, Double-Blinded, Randomized and Placebo-Controlled Clinical Trial.
Drug design, development and therapy
Drug Des Devel Ther
15
null
10.2147/DDDT.S334100
eng
2,021
null
null
2,021
11
4
[BACKGROUND] Propofol-induced injection pain (PIP) is a well-known problem in general anesthesia. We hypothesized that pre-treatment with remimazolam prevents PIP in patients undergoing abortion or curettage. [MATERIALS AND METHODS] In this prospective, single-center, double-blinded, randomized, placebo-controlled clin...
abortion; curettage; lidocaine; propofol injection pain; remimazolam
0.784
108
Pharmaceutical Science; Drug Discovery; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,021
34,763,655
Quantitative flow chamber system for evaluating in vitro biofilms and the kinetics of S. aureus biofilm formation in human plasma media.
BMC microbiology
BMC Microbiol
21
1
10.1186/s12866-021-02379-9
eng
2,021
11
11
2,021
11
11
[BACKGROUND] It has been well established that biofilm formation on orthopaedic implants is a critical event in the pathogenesis of orthopaedic infections, yet the natural history of this process with respect to bacterial adhesion, proliferation, and glycocalyx matrix production remains poorly understood. Moreover, the...
Bioluminescence; In vitro biofilm; Scanning Electron microscopy; Staphylococcus aureus
0.916
147
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,021
34,763,580
Comparison of ultrasound-guided high-intensity focused ultrasound ablation and hysteroscopic myomectomy for submucosal fibroids: a retrospective study.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
Int J Hyperthermia
38
1
10.1080/02656736.2021.1995053
eng
2,021
null
null
null
null
null
[OBJECTIVE] To compare the safety, reintervention and pregnancy outcomes between ultrasound-guided high intensity focused ultrasound (USgHIFU) and hysteroscopic myomectomy (HM) for submucosal fibroids. [MATERIALS AND METHODS] A total of 215 patients with a solitary submucosal fibroid treated by USgHIFU or HM at the thi...
hysteroscopic myomectomy (HM); pregnancy; reintervention rate; submucosal fibroids
0.709
103
Medicine; Physiology; Physiology; Radiological and Ultrasound Technology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine
2,021
34,763,510
Efficacy analysis of Arbidol treatment in patients with 2019 novel coronavirus pneumonia: a retrospective cohort study.
Annals of palliative medicine
Ann Palliat Med
10
10
10.21037/apm-21-2397
eng
2,021
10
null
null
null
null
[BACKGROUND] The aim of this study was to determine whether Arbidol has a good antiviral effect on coronavirus disease 2019 (COVID-19). [METHODS] A retrospective cohort study was performed in one of the treatment centers for COVID-19 patients in China from January 2020 to March 2020. The antiviral drug Arbidol (ARB) wa...
Arbidol; COVID-19-related pneumonia; Coronavirus disease 2019 (COVID-19); antiviral treatment; negativity rate
null
null
null
null
null
34,763,381
Clinical Efficacy and Safety of Controlled Distraction-Compression Technique Using Expandable Titanium Cage in Correction of Posttraumatic Kyphosis.
Journal of Korean Neurosurgical Society
J Korean Neurosurg Soc
65
1
10.3340/jkns.2021.0147
eng
2,022
1
null
2,021
11
15
[OBJECTIVE] To investigate the clinical efficacy and safety of the controlled distraction-compression technique using an expandable titanium cage (ETC) in posttraumatic kyphosis (PTK). [METHODS] We retrospectively studied and collected data on 20 patients with PTK. From January 2014 to December 2017, the controlled dis...
Cage, expandable; Controlled distraction; Kyphosis; Vertebral column resection
0.522
51
Surgery; Neurology; Neuroscience
Medicine; Neuroscience
2,022
34,763,223
Evidence-based healthcare competence of social and healthcare educators: A systematic review of mixed methods.
Nurse education today
Nurse Educ Today
108
null
10.1016/j.nedt.2021.105190
eng
2,022
1
null
2,021
10
30
[BACKGROUND] Social and healthcare operating environments are constantly evolving, so educators have major responsibility for ensuring that Evidence-Based Healthcare is included in the education of future healthcare professionals and applied in their practice. A holistic understanding and implementation of evidence-bas...
Competence; Education; Evidence; Evidence-based; Health educators; Healthcare; Higher education; Mixed-methods; Professional practice; Social care; Systematic review
0.946
109
Education; Nursing
Nursing; Social Sciences
2,022
34,762,845
Multicomponent Staff Training Intervention to Improve Residential Dementia Care (PROCUIDA-Demencia): A Mixed-Methods 2-Arm Cluster Randomized Controlled Pilot and Clinical Outcomes Study.
Journal of the American Medical Directors Association
J Am Med Dir Assoc
23
3
10.1016/j.jamda.2021.09.035
eng
2,022
3
null
2,021
11
8
[OBJECTIVES] To evaluate the feasibility outcomes of implementing a multicomponent staff training intervention (PROCUIDA-Demencia) to promote psychosocial interventions and reduce antipsychotic prescription in Mexican care homes and study its effect on staff's care experience and residents' quality of life. [DESIGN] A ...
Mexico; antipsychotics; care homes; dementia; long-term care; person-centered care; psychosocial interventions; staff training
1.794
136
Geriatrics and Gerontology; Health Policy; Medicine; Nursing
Medicine; Nursing
2,022
34,762,664
The effect of systemic administration of salicylate on the auditory cortex of guinea pigs.
PloS one
PLoS One
16
11
10.1371/journal.pone.0259055
eng
2,021
null
null
2,021
11
11
[OBJECTIVE] To investigate the effect of systemic administration of salicylate as a tinnitus inducing drug in the auditory cortex of guinea pigs. [METHODS] Extracellular recording of spikes of the primary auditory cortex and dorsocaudal areas in healthy male albino Hartley guinea pigs was continuously performed (pre- a...
null
0.852
467
Multidisciplinary
Multidisciplinary
2,021
34,762,054
Remote Digital Psychiatry for Mobile Mental Health Assessment and Therapy: MindLogger Platform Development Study.
Journal of medical Internet research
J Med Internet Res
23
11
10.2196/22369
eng
2,021
11
11
2,021
11
11
[BACKGROUND] Universal access to assessment and treatment of mental health and learning disorders remains a significant and unmet need. There are many people without access to care because of economic, geographic, and cultural barriers, as well as the limited availability of clinical experts who could help advance our ...
EMA; EMI; ESM; digital health; digital phenotyping; digital psychiatry; eHealth; ecological momentary assessment; ecological momentary intervention; experience sampling; experience sampling methods; mHealth; mental health; mobile device; mobile health; mobile phone; smartphone; teletherapy
1.736
214
Health Informatics
Medicine
2,021
34,761,990
Promoting community engagement in a pre-registration nursing programme: a qualitative study of student experiences.
British journal of nursing (Mark Allen Publishing)
Br J Nurs
30
20
10.12968/bjon.2021.30.20.1190
eng
2,021
11
11
null
null
null
[AIMS] To offer child health student nurses a broader learning experience in practice with an autonomous choice of a volunteer placement area. To reflect the changing nature of health care and the move of care closer to home in the placement experience. To evaluate participants' experiences. [DESIGN] This study used de...
Child health; Community engagement; Practice learning; Risk assessment; Student nurse experience; Voluntary placements
null
null
null
null
null
34,761,655
Perturbation of monocyte subsets in iron-deficient children - a shift to a pro-inflammatory state?
Allergologia et immunopathologia
Allergol Immunopathol (Madr)
49
6
10.15586/aei.v49i6.91
eng
2,021
null
null
2,021
11
1
[BACKGROUND] Iron deficiency anemia (IDA) is the most prevalent micronutrient deficiency in preschool children in developing countries including India. IDA is associated with immune perturbation, which is reflected in greater frequency of infections in these children. Recent research has shown three distinct monocyte s...
Children; Flow cytometry; Iron Deficiency anemia; Monocyte subsets
0.438
47
Immunology and Allergy; Medicine; Pulmonary and Respiratory Medicine; Immunology
Immunology and Microbiology; Medicine
2,021
34,761,297
Burden of depression and anxiety disorders per disease codes in patients with lymphoma in Germany.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
30
3
10.1007/s00520-021-06677-w
eng
2,022
3
null
2,021
11
10
[PURPOSE] The aim of this study was to explore the incidence of depression and anxiety disorder diagnoses in a large German cohort of patients with Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) diagnoses in comparison to patients without cancer over a 10-year time frame. [METHODS] Patients with HL (n=687) and NH...
Anxiety disorders; Cancer; Depression; Lymphoma; Oncology
0.984
143
Oncology
Medicine
2,022
34,761,032
A reproductive and sexual health promotion program for women with heart diseases: A protocol for mixed methods study.
Journal of education and health promotion
J Educ Health Promot
10
null
10.4103/jehp.jehp_91_21
eng
2,021
null
null
2,021
9
30
[BACKGROUND] Nowadays, for various reasons, the prevalence of heart diseases has increased in women during reproductive age. These diseases can lead to serious reproductive and sexual-related complications in the affected women. This study will conduct to develop a reproductive health promotion program for women with h...
Health services; Iran; heart disease; preconception care; reproductive health; women
0.331
30
Education; Medicine
Medicine; Social Sciences
2,021
34,760,994
4-week daily airway clearance using oscillating positive-end expiratory pressure versus autogenic drainage in bronchiectasis patients: a randomised controlled trial.
ERJ open research
ERJ Open Res
7
4
10.1183/23120541.00426-2021
eng
2,021
10
null
2,021
11
8
[BACKGROUND] Airway clearance is a fundamental component of bronchiectasis care. Lung clearance index (LCI) is a measurement of ventilation inhomogeneity. Its responsiveness to long-term airway clearance is unknown. We aimed to compare two methods of daily airway clearance over 4 weeks: autogenic drainage (AD) and osci...
null
0.944
52
Pulmonary and Respiratory Medicine
Medicine
2,021
34,760,733
Prevalence of breast imaging reporting and data system (BIRADS) categories and breast consistencies in Central India -A cross-sectional survey.
Journal of family medicine and primary care
J Family Med Prim Care
10
9
10.4103/jfmpc.jfmpc_2494_20
eng
2,021
9
null
2,021
9
30
[BACKGROUND] For recognizing the initial stages of breast cancer, mammography is regarded as one of the best modalities and plays a crucial part to lessen morbidity and mortality. For collaborative studies and planning of preventive strategies, it is significant to have baseline data. Thus, in this survey, the frequenc...
Breast imaging; breast consistency; mammograph
null
null
null
null
null
34,759,984
A case of adenoid cystic carcinoma of trachea: treatment complications and radiotherapy role.
Journal of contemporary brachytherapy
J Contemp Brachytherapy
13
5
10.5114/jcb.2021.109853
eng
2,021
10
null
2,021
10
8
[PURPOSE] Adenoid cystic carcinoma (ACC) of trachea is a relatively rare malignant neoplasm, for which there is a lack of prospective clinical trials investigating treatment effectiveness. Most of the authors prefer surgical resection followed by post-operative radiation therapy in case of incomplete excision. There ar...
adenoid cystic carcinoma; radiotherapy; spinal cord dysfunction; tracheal tumors
0.485
34
Oncology; Radiology, Nuclear Medicine and Imaging
Medicine
2,021
34,759,705
Cardiovascular Disease Risk Factors and 10 Year Risk of Cardiovascular Events among Women over the Age of 40 Years in an Urban Underprivileged Area of Bangalore City.
Journal of mid-life health
J Midlife Health
12
3
10.4103/jmh.jmh_219_20
eng
2,021
null
null
2,021
10
16
[BACKGROUND] Cardiovascular disease (CVD) is one of the leading causes of death among Indian women but not a focus of current strategies to improve women's health. [OBJECTIVES] To assess 10-year CVD risk and estimate the prevalence of CVD risk factors among underprivileged women. [METHODS] A cross-sectional study among...
Cardiovascular disease risk; diabetes; hypertension; obesity
0.283
24
Health; Medicine
Medicine; Social Sciences
2,021
34,759,604
A Toolkit for Strengthening Health Care Policies and Infrastructure of Industries in Developing Countries.
Indian journal of occupational and environmental medicine
Indian J Occup Environ Med
25
3
10.4103/ijoem.ijoem_409_20
eng
2,021
null
null
2,021
10
9
[BACKGROUND] The health risks faced by textile workers calls for a workplace health system that is comprehensive and accessible. To enhance the capacity of workplaces to strengthen their health system, a toolkit was developed by the Business for Social Responsibility (BSR), a non-profit global business network and sust...
Capacity building; health system strengthening; industries; toolkit
0.324
41
Public Health, Environmental and Occupational Health
Medicine
2,021
34,759,448
Proliferation and Differentiation of Dopaminergic Neurons from Human Neuroepithelial Stem Cells Obtained from Embryo Reduction Following In Vitro Fertilization.
Medical archives (Sarajevo, Bosnia and Herzegovina)
Med Arch
75
4
10.5455/medarh.2021.75.280-285
eng
2,021
8
null
null
null
null
[BACKGROUND] Recent advances in stem cell technologies have rekindled an interest in the use of cell therapies to treat patients with Parkinson's disease. Although the transplantation of dopaminergic mesencephalic human fetal brain tissue has previously been reported in the treatment of patients with Parkinson's diseas...
dopaminergic neuron; human neuroepithelial stem cells; in vitro fertilization
0.294
38
Medicine
Medicine
2,021
34,759,236
A Machine Learning Approach for Predicting Real-time Risk of Intraoperative Hypotension in Traumatic Brain Injury.
Journal of neurosurgical anesthesiology
J Neurosurg Anesthesiol
35
2
10.1097/ANA.0000000000000819
eng
2,023
4
1
2,021
11
11
[BACKGROUND] Traumatic brain injury (TBI) is a major cause of death and disability. Episodes of hypotension are associated with worse TBI outcomes. Our aim was to model the real-time risk of intraoperative hypotension in TBI patients, compare machine learning and traditional modeling techniques, and identify key contri...
null
null
null
null
null
null
34,759,229
Efficacy and safety of a parylene-coated occluder for atrial septal defect: a prospective, multi-center, randomized controlled clinical trial.
Chinese medical journal
Chin Med J (Engl)
134
22
10.1097/CM9.0000000000001865
eng
2,021
11
10
2,021
11
10
[BACKGROUND] Nitinol-containing devices are widely used in clinical practice. However, there are concerns about nickel release after nitinol-containing device implantation. This study aimed to compare the efficacy and safety of a parylene-coated occluder vs. a traditional nitinol-containing device for atrial septal def...
null
0.668
84
Medicine
Medicine
2,021
34,759,199
Marking DMEK Grafts Using Bandage Contact Lens Interface Technique: Doubling the Utilization During the Acute Shortage of Donor Corneas.
Cornea
Cornea
41
4
10.1097/ICO.0000000000002922
eng
2,022
4
1
null
null
null
[PURPOSE] The purpose of this study was to describe a novel bandage contact lens (BCL) interface technique for marking the Descemet membrane endothelial keratoplasty (DMEK) graft so that a single donor cornea can be used effectively for 2 recipients during acute shortage. [METHODS] This was a retrospective comparative ...
null
0.968
141
Ophthalmology
Medicine
2,022
34,759,180
SafeSport: Perceptions of Harassment and Abuse From Elite Youth Athletes at the Winter Youth Olympic Games, Lausanne 2020.
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine
Clin J Sport Med
32
3
10.1097/JSM.0000000000000989
eng
2,022
5
1
2,021
11
10
[OBJECTIVE] To analyze the Winter Youth Olympic Games (YOG) 2020 athletes' understanding and perceptions of harassment and abuse in sport and their knowledge of reporting mechanisms. [DESIGN] A cohort study. [SETTING] The Winter YOG2020 in Lausanne, Switzerland. [PARTICIPANTS] Accredited athletes at the YOG2020. [INTER...
null
0.851
121
Physical Therapy, Sports Therapy and Rehabilitation; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,022
34,758,968
Circulating Sex Hormones and Risk of Colorectal Adenomas and Serrated Lesions in Men.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Cancer Epidemiol Biomarkers Prev
31
1
10.1158/1055-9965.EPI-21-0713
eng
2,022
1
null
2,021
11
10
[BACKGROUND] Sex hormones have been implicated in the etiology of colorectal neoplasia in women for over 40 years, but there has been very little investigation of the role of these hormones in men. [METHODS] Using data from an adenoma chemoprevention trial, we conducted a secondary analysis to examine serum hormone lev...
null
null
null
null
null
null
34,758,848
Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagy.
Chinese medicine
Chin Med
16
1
10.1186/s13020-021-00528-w
eng
2,021
11
10
2,021
11
10
[BACKGROUND] Non-alcoholic fatty liver disease (NAFLD) is characterized by ectopic accumulation of triglycerides in the liver. Emerging evidence has demonstrated that lipophagy regulates lipid mobilization and energy homeostasis in the liver. Sirtuin 3 (SIRT3), a mitochondrial NAD[+]-dependent deacetylase, modulates th...
Hepatocytes; Honokiol; Lipid accumulation; Lipolysis; Lipophagy; SIRT3
null
null
null
null
null
34,758,835
The prognostic role of RBP-4 and adiponectin in patients with peripheral arterial disease undergoing lower limb endovascular revascularization.
Cardiovascular diabetology
Cardiovasc Diabetol
20
1
10.1186/s12933-021-01411-6
eng
2,021
11
10
2,021
11
10
[BACKGROUND] RBP4 is an adipokine with an established role in atherosclerosis, while adiponectin has unique anti-inflammatory properties. We investigated the association of RBP4 and adiponectin with the presence of symptomatic peripheral artery disease (PAD) and their possible prognostic role in major adverse cardiovas...
Adiponectin; Inflammation; MACE; Peripheral artery disease; RBP4
2.449
121
Cardiology and Cardiovascular Medicine; Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,021
34,758,755
Maternal sociodemographic characteristics, early pregnancy behaviours, and livebirth outcomes as congenital heart defects risk factors - Northern Ireland 2010-2014.
BMC pregnancy and childbirth
BMC Pregnancy Childbirth
21
1
10.1186/s12884-021-04223-4
eng
2,021
11
10
2,021
11
10
[BACKGROUND] Congenital Heart Defects (CHD) is the most commonly occurring congenital anomaly in Europe and a major paediatric health care concern. Investigations are needed to enable identification of CHD risk factors as studies have given conflicting results. This study aim was to identify maternal sociodemographic c...
Anonymised Data; Cohort; Congenital Heart Defects (CHD); Data Linkage; Northern Ireland; Population Based; Risk Factors
0.96
122
Obstetrics and Gynecology
Medicine
2,021
34,758,716
Association of Serum Interleukin-34 and Insulin Resistance with Cognitive Impairment in Patients with Cerebral Small Vessel Disease.
Current neurovascular research
Curr Neurovasc Res
18
4
10.2174/1567202618666211110113323
eng
2,021
null
null
null
null
null
[OBJECTIVE] Insulin resistance (IR) is a key pathological process during the development of cerebral small vessel disease (CSVD) and vascular cognitive impairment (VCI). The triglyceride- glucose index (TyG index) is considered a novel marker of insulin resistance and can represent peripheral tissue insulin sensitivity...
Insulin resistance; cerebral small vessel disease; cognitive dysfunction; endothelial dysfunction; inflammatory response.; interleukin-34; triglyceride-glucose index
null
null
null
null
null
34,758,462
Factors Leading to Institutionalization among the Oldest Old: Longitudinal Findings from the AgeCoDe-AgeQualiDe Study.
Gerontology
Gerontology
68
8
10.1159/000519709
eng
2,022
null
null
2,021
11
10
[INTRODUCTION] Due to the strong association between old age and the need for long-term care, the number of individuals in need for care is projected to increase noticeably. The aim of this study was to examine the determinants of institutionalization among the oldest old longitudinally. [METHODS] Longitudinal data (fo...
Aged 80 and over; Cognition; Dementia; Depression; Functioning; Institutionalization; Nursing home; Old age home; Oldest old
1.22
120
Geriatrics and Gerontology; Aging
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,758,422
Results of the COVID-19 mental health international for the general population (COMET-G) study.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
Eur Neuropsychopharmacol
54
null
10.1016/j.euroneuro.2021.10.004
eng
2,022
1
null
2,021
10
15
[INTRODUCTION] There are few published empirical data on the effects of COVID-19 on mental health, and until now, there is no large international study. [MATERIAL AND METHODS] During the COVID-19 pandemic, an online questionnaire gathered data from 55,589 participants from 40 countries (64.85% females aged 35.80 ± 13.6...
Anxiety; COVID-19; Conspiracy theories; Depression; Mental disorders; Mental health; Psychiatry; Suicidality
null
null
null
null
null
34,758,176
Association between implementation of a coordinated care pathway in idiopathic scoliosis patients and a reduction in perioperative outcome disparities.
Paediatric anaesthesia
Paediatr Anaesth
32
4
10.1111/pan.14330
eng
2,022
4
null
2,021
12
10
[BACKGROUND] There are well-documented racial and ethnic disparities in treatment and perioperative outcomes for patients with adolescent idiopathic scoliosis. [AIMS] We hypothesize that the implementation of a coordinated care pathway for pediatric patients undergoing posterior spinal fusion for adolescent idiopathic ...
healthcare disparities; quality and safety
0.553
102
Anesthesiology and Pain Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,022
34,757,942
Ultrasonography-guided radiofrequency ablation for solitary T1aN0M0 and T1bN0M0 papillary thyroid carcinoma: a retrospective comparative study.
European journal of endocrinology
Eur J Endocrinol
186
1
10.1530/EJE-21-0580
eng
2,021
12
1
2,021
12
1
[OBJECTIVE] Ultrasonography-guided radiofrequency ablation (RFA) is used to treat small low-risk papillary thyroid carcinoma (PTC) and has achieved favorable results. However, few studies have compared the outcomes of T1aN0M0 and T1bN0M0 PTC treated with ultrasonography-guided RFA. The objective of this study was to co...
null
1.763
179
Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,757,565
Metabolic alterations in carcinoma ex pleomorphic adenoma development of lacrimal glands.
International ophthalmology
Int Ophthalmol
42
4
10.1007/s10792-021-02096-2
eng
2,022
4
null
2,021
11
10
[PURPOSE] To evaluate metabolic alterations along with the carcinoma ex pleomorphic adneoma (CXPA) development of lacrimal glands (LG). [METHODS] Four samples of the normal LG (NLG), 9 of pleomorphic adenoma (PA), 4 of residual PA (rPA), and 4 of CXPA of LG were included. GLUT-1, HIF-1α, FASN, and adipophilin by immuno...
Glycogenesis; Lacrimal glands; Lipogenesis; Metabolism; Pleomorphic adenoma
0.587
57
Ophthalmology
Medicine
2,022
34,757,245
Neural autoantibodies in delirium.
Journal of autoimmunity
J Autoimmun
125
null
10.1016/j.jaut.2021.102740
eng
2,021
12
null
2,021
10
28
[BACKGROUND] Delirium in hospitalized and intensive care unit patients is an emerging condition due to its rapid-onset requiring fast action to mitigate a worse clinical outcome. Although several causes and conditions are known, the association between delirium and neural autoantibodies has often been neglected in coho...
Cognitive dysfunction; Delirium; Neural autoantibody; Postoperative delirium
2.751
147
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,021
34,756,844
Heat sterilisation dramatically reduces filter efficiency of the majority of FFP2 and KN-95 respirators.
The Journal of hospital infection
J Hosp Infect
107
null
10.1016/j.jhin.2020.10.012
eng
2,020
10
22
2,020
10
22
[BACKGROUND] Because of the enormous demand for personal protective equipment and especially respiratory protective devices (respirators) during the initial phase of the corona pandemic shortages arose. Sterilisation of used respirators can reduce these shortages. In our study, respirator testing was carried out after ...
FFP2; KN95; Respirators; disinfection; filter efficiency; heat sterilisation
1.142
143
Medicine; Infectious Diseases; Microbiology
Medicine
2,020
34,756,527
The percentage of residual DCIS in patients diagnosed with primary invasive breast cancer treated with neoadjuvant systemic therapy: A nationwide retrospective study.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Eur J Surg Oncol
48
1
10.1016/j.ejso.2021.10.016
eng
2,022
1
null
2,021
10
22
[INTRODUCTION] Neoadjuvant systemic therapy (NST) is increasingly applied in breast cancer to improve surgical and oncological outcome. Approximately 21% of patients receiving NST achieve pathological complete response (pCR) of the breast. There is disagreement on the definition of pCR with respect to residual DCIS (yp...
Breast cancer; Ductal carcinoma in situ; Neoadjuvant systemic therapy
1.097
123
Medicine; Surgery; Oncology
Medicine
2,022
34,756,487
The impact of shoulder pathology on individuals with distal radius fracture.
Journal of hand therapy : official journal of the American Society of Hand Therapists
J Hand Ther
36
1
10.1016/j.jht.2021.09.002
eng
2,023
null
null
2,021
10
28
[BACKGROUND] Shoulder pathology can occur concurrently with a distal radius fracture (DRF) but few studies have examined this population. [PURPOSE] The purpose of this study was to expand the understanding of the impact of shoulder pathology on individuals with DRF. [STUDY DESIGN] Mixed Methods Design. [METHODS] A tota...
Compensatory mechanisms; Distal radius fracture; Hand therapy; Kinesiophobia; Mixed methods; Shoulder pathology
0.69
74
Rehabilitation; Physical Therapy, Sports Therapy and Rehabilitation
Health Professions; Medicine
2,023
34,755,072
Androgen receptor-neuroendocrine double-negative tumor with squamous differentiation arising from treatment-refractory metastatic castration-resistant prostate cancer.
IJU case reports
IJU Case Rep
4
6
10.1002/iju5.12363
eng
2,021
11
null
2,021
8
22
[INTRODUCTION] Treatment-refractory metastatic castration-resistant prostate cancer is a heterogeneous disease classified into androgen receptor-high prostate cancer, androgen receptor-low prostate cancer, amphicrine prostate cancer co-expressing androgen receptor and neuroendocrine genes, double-negative prostate canc...
androgen receptor; neuroendocrine tumor; squamous differentiation
null
null
null
null
null
34,754,895
Ritalinic acid in urine: Impact of age and dose.
Practical laboratory medicine
Pract Lab Med
27
null
10.1016/j.plabm.2021.e00258
eng
2,021
11
null
2,021
10
23
[OBJECTIVES] The objective of this work was to study the results of urine drug testing for ritalinic acid (RA), the major urinary metabolite of methylphenidate (MP) (e.g., Ritalin®). The impact of age from 4 to 65 years old and older on median levels of RA was investigated as well as potential variations in pH, specifi...
LC/MSMS; Methylphenidate; Ritalinic acid; Urine drug testing
0.364
22
Radiological and Ultrasound Technology; Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology; Health Professions
2,021
34,754,873
Pneumocystis jirovecii and Legionella pneumophila coinfection in a patient with diffuse large B-cell lymphoma: A case report.
World journal of clinical cases
World J Clin Cases
9
28
10.12998/wjcc.v9.i28.8595
eng
2,021
10
6
null
null
null
[BACKGROUND] Diffuse large B-cell lymphoma (DLBCL) is a common non-Hodgkin's lymphoma. R-CHOP is a protocol for long-term chemotherapy for DLBCL patients. Long-term chemotherapy can lead to low immunity and increase the risk of opportunistic pathogen infections in immunocompromised patients. [CASE SUMMARY] We report a ...
Case report; Diffuse large B-cell lymphoma; Legionella pneumophila; Next-generation sequencing; Pneumocystis jirovecii
0.38
38
Medicine
Medicine
2,021
34,754,579
Treatment of BRAF V600E mutated ganglioglioma of the third ventricle with dabrafenib.
Surgical neurology international
Surg Neurol Int
12
null
10.25259/SNI_788_2021
eng
2,021
null
null
2,021
10
19
[BACKGROUND] Ganglioglioma (GG) of the third ventricle is rare. Surgical excision of tumors in this location is associated with high morbidity due to nearby eloquent brain centers. Alternative treatments, when available, should be considered to reduce risks of surgical treatment. [CASE DESCRIPTION] We present the case ...
BRAF inhibitor; Dabrafenib; Ganglioglioma; Targeted therapy; Third ventricle
0.309
48
Neurology; Surgery
Medicine
2,021
34,754,578
Comparison between ultra-high-resolution computed tomographic angiography and conventional computed tomographic angiography in the visualization of the subcallosal artery.
Surgical neurology international
Surg Neurol Int
12
null
10.25259/SNI_887_2021
eng
2,021
null
null
2,021
10
19
[BACKGROUND] The subcallosal artery (ScA) is a single dominant artery arising from the anterior communicating artery. Its injury causes amnesia and cognitive disturbance. The conventional computed tomographic angiography (C-CTA) is a common evaluation method of the intracranial artery. However, to image tinny perforati...
Anterior communicating artery; Subcallosal artery
0.309
48
Neurology; Surgery
Medicine
2,021
34,754,387
Laparoscopy for Crohn's disease: A comprehensive exploration of minimally invasive surgical techniques.
World journal of gastrointestinal surgery
World J Gastrointest Surg
13
10
10.4240/wjgs.v13.i10.1190
eng
2,021
10
27
null
null
null
[BACKGROUND] Along with the unceasing progress of medicine, Crohn's disease (CD), especially complex CD, is no longer a taboo for minimally invasive surgery. However, considering its special disease characteristics, more clinical trials are needed to confirm the safety and feasibility of laparoscopic surgery for CD. [A...
Inflammatory bowel disease; Minimally invasive surgery; Rapid recovery; Ultrasound
null
null
null
null
null
34,754,307
Second Primary Malignancies in Patients with Pancreatic Neuroendocrine Neoplasms: A Population-Based Study on Occurrence, Risk Factors, and Prognosis.
Journal of oncology
J Oncol
2021
null
10.1155/2021/1565089
eng
2,021
null
null
2,021
10
31
[BACKGROUND] This study aimed to evaluate the risk factors of developing second primary malignancies (SPMs) among patients with pancreatic neuroendocrine neoplasms (pNENs) and the prognosis of pNENs patients with SPMs (pSPMs) using data from the Surveillance, Epidemiology, and End Results (SEER) database. [METHODS] Dat...
null
null
null
null
null
null
34,754,285
Integrated Care in Switzerland: Strengths and Weaknesses of a Federal System.
International journal of integrated care
Int J Integr Care
21
4
10.5334/ijic.5668
eng
2,021
null
null
2,021
10
29
[INTRODUCTION] Switzerland's fragmented healthcare system mirrors its federal structure and mix of cultures and languages. Although the Swiss have a higher life expectancy than most of their neighbours, their healthcare system faces similar challenges that call for more integrated care (IC). [AIM/METHOD] This article a...
MeSH; Switzerland; health policies; healthcare systems; integrated delivery systems; political systems
0.614
47
Sociology and Political Science; Health Policy; Health
Medicine; Social Sciences
2,021
34,754,209
Timing and Efficacy of 595-nm Pulsed-Dye Laser Combined with 0.5% Timolol Maleate Solution in the Treatment of Superficial Infantile Hemangiomas.
Clinical, cosmetic and investigational dermatology
Clin Cosmet Investig Dermatol
14
null
10.2147/CCID.S337850
eng
2,021
null
null
2,021
11
2
[PURPOSE] Infantile hemangioma (IH) is the most common benign tumor in infancy, and superficial IH is the most common type. IH can reportedly resolve spontaneously, but this is associated with complications, such as scars, atrophy, hypopigmentation, telangiectasia, and skin sagging, in 70% of cases. This study explores...
infantile hemangiomas; pulsed-dye laser; timing and efficacy; timolol maleate solution
0.739
59
Dermatology
Medicine
2,021
34,753,841
Satisfaction of Oral Health Education among Parents and Caregivers Regarding Children with Special Healthcare Needs in Riyadh, Saudi Arabia.
The journal of contemporary dental practice
J Contemp Dent Pract
22
8
null
eng
2,021
8
1
2,021
8
1
[AIM AND OBJECTIVE] The aim of the study was to evaluate the satisfaction of an oral health promotion program among parents and caregivers of children with special healthcare needs (CSHCN) in Riyadh, Saudi Arabia. [MATERIALS AND METHODS] A digital survey using Google forms was used during an event to commemorate the Wo...
Children; Disabilities; Health promotion; Oral health Special needs.
0.29
53
Dentistry
Dentistry
2,021
34,753,813
Effect of Prone Positioning on Clinical Outcomes of Non-Intubated Subjects With COVID-19.
Respiratory care
Respir Care
67
4
10.4187/respcare.09362
eng
2,022
4
null
2,021
11
9
[BACKGROUND] Awake prone positioning (APP) has been recently proposed as an adjunctive treatment for non-intubated coronavirus disease 2019 (COVID-19) patients requiring oxygen therapy to improve oxygenation and reduce the risk of intubation. However, the magnitude of the effect of APP on clinical outcomes in these pat...
COVID-19; ICU admission; SARS-CoV-2; awake prone positioning; intubation; mortality
0.656
112
Critical Care and Intensive Care Medicine; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022
34,753,616
Comparable survival benefit of local excision versus radical resection for 10- to 20-mm rectal neuroendocrine tumors.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Eur J Surg Oncol
48
4
10.1016/j.ejso.2021.10.029
eng
2,022
4
null
2,021
11
2
[OBJECTIVE] The optimal surgical management for 10- to 20-mm rectal neuroendocrine tumors (RNET) is still a matter of debate. This study aimed to explore the optimal surgical approach for 10- to 20-mm RNET by comparing the outcomes between local excision and radical resection. [METHOD] We extracted clinicopathological ...
Prognosis; Rectal neuroendocrine tumors; SEER; Surgery
1.097
123
Medicine; Surgery; Oncology
Medicine
2,022
34,753,521
Have the Diagnoses of Patients Transported by Ambulances Changed in the Early Stage of the COVID-19 Pandemic?
Prehospital and disaster medicine
Prehosp Disaster Med
37
1
10.1017/S1049023X21001229
eng
2,022
2
null
2,021
11
10
[INTRODUCTION] Since December 2019, emergency services and Emergency Medical Service (EMS) systems have been at the forefront of the fight against the coronavirus disease 2019 (COVID-19) pandemic world-wide. [OBJECTIVE] The objective of this study was to examine the reasons and the necessity of transportation to the em...
COVID-19; Emergency Medical Service; ambulance; pandemic
0.477
62
Emergency Medicine; Emergency Nursing
Medicine; Nursing
2,022
34,753,461
ICD-11 extension codes support detailed clinical abstraction and comprehensive classification.
BMC medical informatics and decision making
BMC Med Inform Decis Mak
21
Suppl 6
10.1186/s12911-021-01635-2
eng
2,021
11
9
2,021
11
9
[BACKGROUND] The new International Classification of Diseases-11th revision (ICD-11) succeeds ICD-10. In the three decades since ICD-10 was released, demands for detailed information on the clinical history of a morbid patient have increased. [METHODS] ICD-11 has now implemented an addendum chapter X called "Extension ...
Classification; Extension codes; ICD11; International Classification of Diseases
0.833
107
Health Policy; Computer Science Applications; Health Informatics
Computer Science; Medicine
2,021
34,753,191
Long-Term Risk of Major Bleeding after Discontinuing Anticoagulation for Unprovoked Venous Thromboembolism: A Systematic Review and Meta-analysis.
Thrombosis and haemostasis
Thromb Haemost
122
7
10.1055/a-1690-8728
eng
2,022
7
null
2,021
11
9
[BACKGROUND] The long-term risk of major bleeding after discontinuing anticoagulant therapy for a first unprovoked venous thromboembolism (VTE) is uncertain. [OBJECTIVES] To determine the incidence of major bleeding up to 5 years after discontinuing anticoagulation for a first unprovoked VTE. [METHODS] We searched MEDL...
null
1.565
211
Hematology
Medicine
2,022
34,752,586
Bowel Ultrasound: a Non-invasive, Easy to Use Method to Predict the Need to Intensify Therapy in Inflammatory Bowel Disease Patients.
Journal of gastrointestinal and liver diseases : JGLD
J Gastrointestin Liver Dis
30
4
10.15403/jgld-3726
eng
2,021
12
21
2,021
12
21
[BACKGROUND AND AIMS] Bowel ultrasound (BU) is a non-invasive, inexpensive, widely available tool, valuable for inflammatory bowel disease (IBD) assessment. The aim of the present study was to investigate the clinical utility of BU to predict the need to intensify therapy in IBD patients. [METHODS] One hundred seventee...
null
0.496
62
Gastroenterology; Medicine
Medicine
2,021
34,750,661
Diagnostic performance of diffusion-weighted MR neurography as an adjunct to conventional MRI for the assessment of brachial plexus pathology.
European radiology
Eur Radiol
32
4
10.1007/s00330-021-08324-8
eng
2,022
4
null
2,021
11
9
[OBJECTIVE] To investigate the diagnostic performance of diffusion-weighted (DW) MR neurography as an adjunct to conventional MRI for the assessment of brachial plexus pathology. [METHODS] DW MR neurography scans (short tau inversion recovery fat suppression and b-value of 800 s/mm[2]) of 15 consecutive patients with a...
Brachial Plexus; Diagnostic imaging; Diffusion magnetic resonance imaging; Sensitivity and specificity
1.733
182
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
34,750,325
Long noncoding RNA KIF9-AS1 promotes cell apoptosis by targeting the microRNA-148a-3p/suppressor of cytokine signaling axis in inflammatory bowel disease.
European journal of gastroenterology hepatology
Eur J Gastroenterol Hepatol
33
1S Suppl 1
10.1097/MEG.0000000000002309
eng
2,021
12
1
null
null
null
[OBJECTIVE] Inflammatory bowel disease (IBD) is a chronic intestinal disease. This study was attempted to investigate the effects of long noncoding RNA KIF9-AS1 (KIF9-AS1) on the development of IBD and its underlying mechanism of action. [METHODS] Quantitative real time PCR (qRT-PCR) was implemented to examine the expr...
null
null
null
null
null
null
34,750,297
Growth deficits in antiretroviral and HIV-exposed uninfected versus unexposed children in Malawi and Uganda persist through 60 months of age.
AIDS (London, England)
AIDS
36
4
10.1097/QAD.0000000000003122
eng
2,022
3
15
null
null
null
[OBJECTIVE] To compare childhood physical growth among antiretroviral drug and maternal HIV-exposed uninfected (AHEU) compared with HIV-unexposed uninfected (HUU) children. [DESIGN] Longitudinal follow-up of PROMISE trial (NCT01061151) AHEU and age-matched and sex-matched HUU children, enrolled (September 2013 to Octob...
null
1.26
233
Infectious Diseases; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
34,749,965
Fine particulate matter and vasoactive 20-hydroxyeicosatetraenoic acid: Insights into the mechanisms of the prohypertensive effects of particulate air pollution.
The Science of the total environment
Sci Total Environ
806
Pt 3
10.1016/j.scitotenv.2021.151298
eng
2,022
2
1
2,021
10
29
[BACKGROUND] Emerging evidence suggests that biological intermediates play an important role in initiating fine particulate matter (PM2.5)-associated prohypertensive pathways, but sensitive biomarkers for this pathway are lacking. [AIM] To explore whether short-term exposure to PM2.5 is associated with the concentratio...
20-HETE; Hypertension; Lipid; Organic carbon; PM(2.5)
1.946
399
Environmental Chemistry; Environmental Engineering; Pollution; Waste Management and Disposal
Environmental Science
2,022
34,749,716
Prevalence, risk factors, and management practices of primary dysmenorrhea among young females.
BMC women's health
BMC Womens Health
21
1
10.1186/s12905-021-01532-w
eng
2,021
11
8
2,021
11
8
[BACKGROUND] Primary dysmenorrhea (PD) is one of the most common gynecological conditions among young females, which has a significant negative impact on health-related quality of life and productivity. Despite its high prevalence, the evidence is limited regarding the management-seeking practices and its perceived eff...
Lebanon; Management-seeking practices; Menstrual pain; Non-steroidal anti-inflammatory drugs; Prevalence; Primary dysmenorrhea; Risk factors
0.742
73
Medicine; Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,021
34,749,491
Rehabilitation and COVID-19: rapid living systematic review by Cochrane Rehabilitation Field - third edition. Update as of June 30th, 2021.
European journal of physical and rehabilitation medicine
Eur J Phys Rehabil Med
57
5
10.23736/S1973-9087.21.07301-9
eng
2,021
10
null
null
null
null
[INTRODUCTION] This paper updates and summarizes the current evidence informing rehabilitation of patients with COVID-19 and/or describing the consequences of the disease and its treatment. [EVIDENCE ACQUISITION] Studies published from May 1[st] to June 30[th], 2021 were selected, excluding descriptive studies and expe...
null
1.089
79
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation
Health Professions; Medicine
2,021
34,749,383
Fungal Necrotizing Scleritis After Intravitreal Injection Therapy.
Cornea
Cornea
40
12
10.1097/ICO.0000000000002670
eng
2,021
12
1
null
null
null
[PURPOSE] To report a case of infectious necrotizing scleritis secondary to Aspergillus terreus after intravitreal injection therapy. [METHODS] This is a case report with literature review. [RESULTS] A 98-year-old woman receiving intravitreal aflibercept injections for neovascular age-related macular degeneration in th...
null
1.336
141
Ophthalmology
Medicine
2,021
34,749,227
Application of the Quadruple Aim to evaluate the operational impact of a telemedicine program.
Healthcare (Amsterdam, Netherlands)
Healthc (Amst)
9
4
10.1016/j.hjdsi.2021.100593
eng
2,021
12
null
2,021
11
5
[BACKGROUND] In response to the COVID-19 pandemic, telemedicine utilization has increased dramatically, yet most institutions lack a standardized approach to determine how much to invest in these programs. [METHODS] We used the Quadruple Aim to evaluate the operational impact of CardioClick, a program replacing in-pers...
Cardiovascular disease; Efficiency; Preventive medicine; Telemedicine
0.533
33
Health Policy
Medicine
2,021
34,749,127
Ultrasound examination of tibiofibular widening of forceful knee flexion is recommended for patients with proximal tibiofibular joint instability.
The Knee
Knee
33
null
10.1016/j.knee.2021.10.021
eng
2,021
12
null
2,021
11
6
[BACKGROUND] Proximal tibiofibular joint (PTFJ) instability is uncommon, resulting from violent twisting motions of the flexed knee during sport activities. No known image variables functionally relate the degrees of PTFJ instability. [OBJECTIVE] This study used ultrasound imaging to quantify the discrimination thresho...
KOOS; Outcome; Predictor; Proximal tibiofibular joint instability; Ultrasonography
0.728
98
Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,021
34,749,022
A pilot study of multiple time points and multidomain assessment in cerebrospinal fluid tap test for patients with idiopathic normal pressure hydrocephalus.
Clinical neurology and neurosurgery
Clin Neurol Neurosurg
210
null
10.1016/j.clineuro.2021.107012
eng
2,021
11
null
2,021
11
2
[OBJECTIVE] Our study aimed to identify the appropriate evaluation time point and assessment forthe CSF tap test(TT) to predict the shunting responsiveness of patients with idiopathic normal-pressure hydrocephalus (iNPH). [METHODS] Eighty-eight inpatients with clinically possible iNPH who underwent CSF TT at multiple t...
null
0.571
89
Medicine; Surgery; Neurology
Medicine
2,021
34,748,582
Consent to minimally invasive tissue sampling procedures in children in Mozambique: A mixed-methods study.
PloS one
PLoS One
16
11
10.1371/journal.pone.0259621
eng
2,021
null
null
2,021
11
8
[BACKGROUND] Minimally invasive tissue sampling (MITS), also named minimally invasive autopsy is a post-mortem method shown to be an acceptable proxy of the complete diagnostic autopsy. MITS improves the knowledge of causes of death (CoD) in resource-limited settings. Its implementation requires understanding the compo...
null
0.852
467
Multidisciplinary
Multidisciplinary
2,021