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34,781,870 | Fourth Generation of Synthetic Cannabinoid Receptor Agonists: A Review on the Latest Insights. | Current pharmaceutical design | Curr Pharm Des | 28 | 32 | 10.2174/1381612827666211115170521 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] Over the past few years, an emerging number of new psychoactive substances (NPSs) entered the illicit market. NPSs are designed to resemble the effects of classical drugs of abuse, reinforcing their effects and duration. Among the most abused NPS, synthetic cannabinoids are cannabinoid receptor agonists (S... | Synthetic cannabinoids; THC; fourth generation; new psychoactive substances; receptor agonists; toxicology | 0.58 | 190 | Drug Discovery; Pharmacology | Pharmacology, Toxicology and Pharmaceutics | 2,022 |
34,781,599 | Administration of red ginseng regulates microRNA expression in a mouse model of endometriosis. | Clinical and experimental reproductive medicine | Clin Exp Reprod Med | 48 | 4 | 10.5653/cerm.2021.04392 | eng | 2,021 | 12 | null | 2,021 | 9 | 1 | [OBJECTIVE] Red ginseng (RG) exerts anti-inflammatory, anti-proliferative, and immunomodulatory effects on endometriosis through the regulation of microRNA (miRNA) expression. It may also ameliorate endometriosis by affecting the expression of multiple miRNAs simultaneously, rather than acting on a single miRNA at a gi... | Endometriosis; Medical informatics; MicroRNAs; Panax; Red ginseng | 0.479 | 36 | Reproductive Medicine | Medicine | 2,021 |
34,781,390 | Comparison of the Functional and Radiological Outcomes of Single- and Two-Stage Bilateral Open Wedge High Tibial Osteotomy. | Zeitschrift fur Orthopadie und Unfallchirurgie | Z Orthop Unfall | 161 | 1 | 10.1055/a-1611-0316 | eng | 2,023 | 2 | null | 2,021 | 11 | 15 | [PURPOSE] This study compared the functional and radiological outcomes and complications of single- (SS) and two-stage (TS) bilateral high tibial osteotomy (HTO). [METHODS] From 2014 to 2018, 48 patients underwent bilateral HTO surgery for osteoarthritis. The outcomes of SS in 28 knees and TS in 32 knees were compared ... | null | 0.279 | 40 | Medicine; Orthopedics and Sports Medicine; Surgery | Medicine | 2,023 |
34,780,947 | Validation of the GLASS Staging Systems in Patients With Chronic Limb-Threatening Ischemia Undergoing De Novo Infrainguinal Revascularization. | Annals of vascular surgery | Ann Vasc Surg | 81 | null | 10.1016/j.avsg.2021.09.054 | eng | 2,022 | 4 | null | 2,021 | 11 | 12 | [OBJECTIVES] The Global Limb Anatomic Staging System (GLASS) was proposed for evaluating the anatomic complexity of arterial disease in patients with chronic limb-threatening ischemia (CLTI). We aimed to examine the relationship between GLASS stage and treatment outcomes after infrainguinal revascularization in patient... | Chronic limb-threatening ischemia; Global Limb Anatomic Staging System (GLASS); Infrainguinal revascularization; Prognosis; WIfI classification | 0.65 | 87 | Cardiology and Cardiovascular Medicine; Medicine; Surgery | Medicine | 2,022 |
34,780,656 | Evaluation of a Quality Improvement Experience for Family Medicine Clerkship Students. | Family medicine | Fam Med | 53 | 10 | 10.22454/FamMed.2021.702090 | eng | 2,021 | 11 | null | null | null | null | [BACKGROUND AND OBJECTIVES] There is emphasis on systems-based practice competencies and quality improvement (QI) training in postgraduate medical education. However, we lack effective approaches to provide experiences in these areas during undergraduate medical education. To address this, we developed a novel approach... | null | 0.482 | 77 | Family Practice | Medicine | 2,021 |
34,780,653 | Impact of the Rural Physician Associate Program on Workforce Outcomes. | Family medicine | Fam Med | 53 | 10 | 10.22454/FamMed.2021.563022 | eng | 2,021 | 11 | null | null | null | null | [BACKGROUND AND OBJECTIVES] The Rural Physician Associate Program (RPAP) at the University of Minnesota Medical School (UMMS) is a 9-month rural longitudinal integrated clerkship (LIC) for third-year medical students built on a foundation of family medicine. The purpose of this study was to examine the relationships be... | null | 0.482 | 77 | Family Practice | Medicine | 2,021 |
34,780,393 | Cerebrospinal Fluid Penetration of Vancomycin During Continuous Infusion Therapy in Patients With Nosocomial Ventriculitis. | Therapeutic drug monitoring | Ther Drug Monit | 43 | 6 | 10.1097/FTD.0000000000000907 | eng | 2,021 | 12 | 1 | null | null | null | [BACKGROUND] This study aimed to evaluate the utility of a commercial kit used to measure serum vancomycin concentrations to determine vancomycin concentrations in cerebrospinal fluid (CSF) samples and evaluate CSF penetration when administered as a continuous high-dose infusion in patients with nosocomial ventriculiti... | null | 0.555 | 105 | Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,021 |
34,780,317 | Prevalence of chronic pain in a national cohort of patients with limb-girdle muscular dystrophy: a cross-sectional study. | Disability and rehabilitation | Disabil Rehabil | 44 | 25 | 10.1080/09638288.2021.1998669 | eng | 2,022 | 12 | null | 2,021 | 11 | 15 | [PURPOSE] The aim was to investigate the prevalence, characteristics, predictors, and consequences of chronic pain in a national cohort of patients with limb-girdle muscular dystrophy (LGMD). [MATERIALS AND METHODS] Questionnaires were sent to all Danish LGMD patients (≥18 years of age) registered with the National Reh... | Limb-girdle muscular dystrophy; functioning; pain prevalence; predictors; psychological distress; quality of life; rehabilitation | 0.762 | 140 | Rehabilitation | Medicine | 2,022 |
34,780,068 | Patient posture correction and alignment using mixed reality visualization and the HoloLens 2. | Medical physics | Med Phys | 49 | 1 | 10.1002/mp.15349 | eng | 2,022 | 1 | null | 2,021 | 11 | 22 | [PURPOSE] The purpose of this study was to develop and preliminarily test a radiotherapy system for patient posture correction and alignment using mixed reality (MixR) visualization. The write-up of this work also provides an opportunity to introduce the concepts and technology of MixR for a medical physics audience wh... | HoloLens 2; SGRT; augmented reality; mixed reality | 1.072 | 218 | Biophysics; Medicine; Radiology, Nuclear Medicine and Imaging | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,779,899 | Floating hip in polytraumatized patients: complications, mechanism of injury, and surgical strategy. | International orthopaedics | Int Orthop | 46 | 2 | 10.1007/s00264-021-05262-4 | eng | 2,022 | 2 | null | 2,021 | 11 | 15 | [PURPOSE] Floating hip fractures are severe and rare injuries with high complication rate and lack of standard management. The purpose of this retrospective study was to review the outcomes of a case series of polytraumatized patients with floating hip injuries, in order to describe the relationship between complicatio... | Complication; Floating; Floating hip; Hip; Mechanism; Polytrauma; Treatment | 0.988 | 116 | Orthopedics and Sports Medicine; Surgery | Medicine | 2,022 |
34,779,741 | Central Recruitment: A process for engaging and recruiting individuals with spinal cord injury/disease in research at Toronto Rehabilitation Institute. | The journal of spinal cord medicine | J Spinal Cord Med | 44 | sup1 | 10.1080/10790268.2021.1970898 | eng | 2,021 | null | null | null | null | null | [CONTEXT] Insufficient recruitment is a barrier to research and limits statistical power. We describe an initiative aimed to streamline recruitment and consent processes for inpatients with spinal cord injury or disease (SCI/D) via implementation of a Central Recruitment (CR) process. The CR process adhered to ethical ... | Ethics; Organizational efficiency; Patient recruitment; Rehabilitation research; Spinal cord injuries | 0.458 | 81 | Neurology | Medicine | 2,021 |
34,779,689 | Effect of metformin intervention on circulating irisin levels in polycystic ovary syndrome: a systematic review and collaborative meta-analysis. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology | Gynecol Endocrinol | 38 | 3 | 10.1080/09513590.2021.1998439 | eng | 2,022 | 3 | null | 2,021 | 11 | 15 | [BACKGROUND] Irisin is an adipo-myokine with potential implications in metabolic disorders such as polycystic ovary syndrome (PCOS). Despite of a strong evidence showing increased irisin level in PCOS, there is no conclusive evidence on the effect of metformin intervention on circulatory irisin in PCOS. [AIM] The aim o... | Irisin; meta-analysis; metformin; polycystic ovary syndrome | 0.562 | 79 | Obstetrics and Gynecology; Endocrinology; Endocrinology, Diabetes and Metabolism | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,779,581 | Use of paracetamol (acetaminophen) as a nonprescription analgesic and semen quality in young men: A cross-sectional study. | Andrology | Andrology | 10 | 3 | 10.1111/andr.13129 | eng | 2,022 | 3 | null | 2,021 | 11 | 25 | [BACKGROUND] Paracetamol (acetaminophen) is a frequently used nonprescription analgesic with suggested endocrine-disrupting properties. Epidemiological evidence on the effect of paracetamol on male fecundity is sparse. [OBJECTIVES] To investigate if the use of paracetamol as an oral nonprescription mild analgesic was a... | male fecundity; nonprescription analgesic; paracetamol; semen analysis; semen quality | 1.068 | 76 | Endocrinology, Diabetes and Metabolism; Reproductive Medicine; Urology; Endocrinology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,779,570 | Attitudes, practices and experiences of medical specialists towards email communication with their patients. | Internal medicine journal | Intern Med J | 53 | 4 | 10.1111/imj.15627 | eng | 2,023 | 4 | null | 2,022 | 8 | 24 | [BACKGROUND] The medical profession has been slow in embracing email as a means of improving communication with patients. [AIMS] To explore the attitudes, practices and experiences of senior medical specialists towards email communication with their patients. [METHODS] A cross-sectional qualitative interview of 30 medi... | COVID-19; communication; doctor-patient; email; risk management | 0.585 | 85 | Internal Medicine | Medicine | 2,023 |
34,779,303 | Telephone versus in-person genetic counseling for hereditary cancer risk: Patient predictors of differential outcomes. | Journal of telemedicine and telecare | J Telemed Telecare | 30 | 2 | 10.1177/1357633X211052220 | eng | 2,024 | 2 | null | 2,021 | 11 | 15 | [PURPOSE] Telegenetics has become the predominant mode of cancer genetic counseling during the COVID-19 pandemic. We sought to identify potential patient-level contraindicators for telegenetic genetic counseling. [METHODS] We analyzed post-counseling (pre-result disclosure) follow-up data from a randomized noninferiori... | BRCA1; BRCA2; Telegenetics; cancer; genetic counseling; numeracy; outcomes; telehealth | 1.384 | 95 | Health Informatics | Medicine | 2,024 |
34,779,110 | Associations between systemic medications and development of wet age-related macular degeneration. | Acta ophthalmologica | Acta Ophthalmol | 100 | 5 | 10.1111/aos.15056 | eng | 2,022 | 8 | null | 2,021 | 11 | 14 | [PURPOSE] To examine whether systemic medications are associated with the subsequent development of wet age-related macular degeneration (AMD). [METHODS] A retrospective study of 259 562 individuals based on registry data, from January 1, 2001, to December 31, 2017. End-point event was the International Classification ... | atorvastatin; bicalutamide; calcium channel blockers; estradiol; pharmacoepidemiology; real-world evidence; wet age-related macular degeneration | 1.128 | 110 | Medicine; Ophthalmology | Medicine | 2,022 |
34,779,020 | A strategy to reduce the sensitivity of inhomogeneous magnetization transfer (ihMT) imaging to radiofrequency transmit field variations at 3 T. | Magnetic resonance in medicine | Magn Reson Med | 87 | 3 | 10.1002/mrm.29055 | eng | 2,022 | 3 | null | 2,021 | 11 | 15 | [PURPOSE] To minimize the sensitivity of inhomogeneous magnetization transfer gradient-echo (ihMT-GRE) imaging to radiofrequency (RF) transmit field (B1+) inhomogeneities at 3 T. [METHODS] The ihMT-GRE sequence was optimized by varying the concentration of the RF saturation energy over time, obtained by increasing the ... | ihMT; inhomogeneous magnetization transfer; magnetization transfer; myelin; neuroimaging; radiofrequency field inhomogeneities | 1.349 | 257 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,022 |
34,778,994 | A study of diabetic ketoacidosis in the pregnant population in the United Kingdom: Investigating the incidence, aetiology, management and outcomes. | Diabetic medicine : a journal of the British Diabetic Association | Diabet Med | 39 | 4 | 10.1111/dme.14743 | eng | 2,022 | 4 | null | 2,021 | 11 | 28 | [AIM] To estimate the incidence of diabetic ketoacidosis (DKA) among pregnant women, describe its clinical features, management and outcomes and identify the risk factors for the condition. [METHODS] A national population-based case-control study was conducted in the UK using the UK Obstetric Surveillance System betwee... | diabetes; incidence; ketoacidosis; population-based study; pregnancy; stillbirth | 1.246 | 171 | Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,778,009 | Antimicrobial resistance in neonates with suspected sepsis. | Public health action | Public Health Action | 11 | Suppl 1 | 10.5588/pha.21.0038 | eng | 2,021 | 11 | 1 | null | null | null | [SETTING] Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. [OBJECTIVE] To determine the pattern of antimicrobial resistance and hospital exit outcomes in neonates with suspected sepsis in a tertiary neonatal intensive care unit (NICU). [DESIGN] This hospital-based cohort study was conducted to follow pat... | NICU; antimicrobial resistance; neonatal sepsis | null | null | null | null | null |
34,777,706 | Type 2 diabetes mellitus risk assessment among doctors in Ondo state. | Malawi medical journal : the journal of Medical Association of Malawi | Malawi Med J | 33 | 2 | 10.4314/mmj.v33i2.6 | eng | 2,021 | 6 | null | null | null | null | [INTRODUCTION] Diabetes Mellitus (DM) has become a disease of public health importance in Nigeria. Early identification of DM risk is important in the reduction of this disease burden. This study assessed ten-year risk of developing type 2 DM among some medical doctors in Ondo State. [METHODS] This was a cross-sectiona... | doctor; nigeria; risk; type 2 diabetes mellitus | 0.393 | 30 | Medicine | Medicine | 2,021 |
34,777,389 | Spatial Profiles of Intratumoral PD-1[+] Helper T Cells Predict Prognosis in Head and Neck Squamous Cell Carcinoma. | Frontiers in immunology | Front Immunol | 12 | null | 10.3389/fimmu.2021.769534 | eng | 2,021 | null | null | 2,021 | 10 | 28 | [BACKGROUND] Functional interactions between immune cells and neoplastic cells in the tumor immune microenvironment have been actively pursued for both biomarker discovery for patient stratification, as well as therapeutic anti-cancer targets to improve clinical outcomes. Although accumulating evidence indicates that i... | Head and neck cancer; PD-1; helper T cell; multiplex immunohistochemistry; tumor heterogeneity | 2.331 | 259 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,021 |
34,777,361 | Clinical Features and Risk Factors for Active Tuberculosis in Takayasu Arteritis: A Single-Center Case-Control Study. | Frontiers in immunology | Front Immunol | 12 | null | 10.3389/fimmu.2021.749317 | eng | 2,021 | null | null | 2,021 | 10 | 29 | [BACKGROUNDS] Takayasu arteritis (TAK) is a chronic, granulomatous vasculitis correlated with tuberculosis (TB). The two diseases share similar pathological characteristics and clinical manifestations which increase the difficulty to diagnose. Active tuberculosis (ATB) has implications for treatment strategies in TAK p... | T-SPOT.TB; Takayasu arteritis; hsCRP; risk factor (RF); tuberculosis | 2.331 | 259 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,021 |
34,776,702 | Arthroplasty Followed by Distraction Osteogenesis Versus Distraction Osteogenesis Followed by Arthroplasty in the Management of TMJ Ankylosis: A Comparative Study. | Journal of maxillofacial and oral surgery | J Maxillofac Oral Surg | 20 | 4 | 10.1007/s12663-020-01463-3 | eng | 2,021 | 12 | null | 2,020 | 10 | 7 | [AIM] To compare treatment outcome of arthroplasty followed by distraction osteogenesis (AFD) and distraction osteogenesis followed by arthroplasty (DFA) in the management of mandibular deficiencies in temporomandibular joint (TMJ) ankylosis. [MATERIALS AND METHODS] A total of 20 patients with TMJ Ankylosis were includ... | Airway; Arthroplasty; Distraction osteogenesis; Retrognathia; TMJ ankylosis | 0.317 | 36 | Oral Surgery; Otorhinolaryngology; Surgery | Dentistry; Medicine | 2,021 |
34,776,435 | A Decade of Decline in Serious Cognitive Problems Among Older Americans: A Population-Based Study of 5.4 Million Respondents. | Journal of Alzheimer's disease : JAD | J Alzheimers Dis | 85 | 1 | 10.3233/JAD-210561 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] Numerous studies suggest the prevalence of dementia has decreased over the past several decades in Western countries. Less is known about whether these trends differ by gender or age cohort, and if generational differences in educational attainment explain these trajectories. [OBJECTIVE] 1) To detect tempo... | Cognitive impairment; dementia; memory; temporal trends | 1.146 | 188 | Clinical Psychology; Geriatrics and Gerontology; Medicine; Psychiatry and Mental Health; Neuroscience | Medicine; Neuroscience; Psychology | 2,022 |
34,776,431 | Anorectal dysfunction in multiple sclerosis patients: A pilot study on the effect of an individualized rehabilitation approach. | NeuroRehabilitation | NeuroRehabilitation | 50 | 1 | 10.3233/NRE-210226 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] Anorectal dysfunction (ARD), especially bowel incontinence, frequently compromises the quality of life in multiple sclerosis (MS) patients. The effect of rehabilitation procedures has not been clearly established. [OBJECTIVE] To determine the effect of an individualized rehabilitation approach on bowel inc... | Multiple sclerosis; biofeedback; bowel incontinence; high resolution anorectal manometry | null | null | null | null | null |
34,776,365 | Prediction of Underestimation Using Contrast-Enhanced Spectral Mammography in Patients Diagnosed as Ductal Carcinoma In Situ on Preoperative Core Biopsy. | Clinical breast cancer | Clin Breast Cancer | 22 | 3 | 10.1016/j.clbc.2021.10.004 | eng | 2,022 | 4 | null | 2,021 | 10 | 9 | [BACKGROUND] To assess the performance of contrast-enhanced spectral mammography (CESM) for the prediction of DCIS underestimation in comparison with mammography, breast US, and breast MRI. [PATIENTS AND METHODS] We prospectively enrolled patients diagnosed with DCIS on preoperative core biopsy. Visibility, lesion type... | Breast cancer; Contrast-enhanced spectral mammography; Ductal carcinoma in situ; Underestimation | 0.862 | 85 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,776,268 | Breastfeeding and risk of febrile seizures in the first 3 years of life: The Japan Environment and Children's Study. | Brain development | Brain Dev | 44 | 3 | 10.1016/j.braindev.2021.10.008 | eng | 2,022 | 3 | null | 2,021 | 11 | 12 | [OBJECTIVE] Our study was conducted to examine the association between breastfeeding and febrile seizures (FS) in the first 3 years of life. [METHODS] We analyzed the dataset of the Japan Environment and Children's Study (JECS), which is a birth cohort study undertaken to elucidate the influence of environmental factor... | Breastfeeding; Febrile seizures; JECS | null | null | null | null | null |
34,776,098 | Long-term outcomes of necrotizing pneumonia. | Anales de pediatria | An Pediatr (Engl Ed) | 95 | 5 | 10.1016/j.anpede.2020.10.002 | eng | 2,021 | 11 | null | 2,020 | 11 | 3 | [INTRODUCTION] Necrotizing pneumonia (NP) is a serious complication of community-acquired pneumonia characterised by the destruction of normal lung parenchyma. No study has evaluated the repercussions of the lung damage in the years following the episode. The aim of this study was to assess the long-term impact on lung... | Children; Lung function; Necrotizing pneumonia; Pneumonia | 0.312 | 38 | Pediatrics, Perinatology and Child Health | Medicine | 2,021 |
34,775,952 | Methodological aspects for accelerometer-based assessment of physical activity in heart failure and health. | BMC medical research methodology | BMC Med Res Methodol | 21 | 1 | 10.1186/s12874-021-01350-6 | eng | 2,021 | 11 | 14 | 2,021 | 11 | 14 | [BACKGROUND] For valid accelerometer-assessed physical activity (PA) data, several methodological aspects should be considered. We aimed to 1) visualize the applicability of absolute accelerometer cut-offs to classify PA intensity, 2) verify recommendations to measure PA over 7 days by examining inter-day variability a... | Activity monitor; Leisure activities; Sedentary behavior; Wearing time | 1.933 | 176 | Epidemiology; Health Informatics | Medicine | 2,021 |
34,775,890 | Risk factors of decompensated tinnitus and the interaction effect of anxiety and poor sleep on decompensated tinnitus: a multicenter study. | Acta oto-laryngologica | Acta Otolaryngol | 141 | 12 | 10.1080/00016489.2021.1922754 | eng | 2,021 | 12 | null | 2,021 | 11 | 13 | [BACKGROUND] Decompensated tinnitus substantially degrades quality of life. Anxiety and poor sleep are comorbidities in decompensated tinnitus. [OBJECTIVE] This multicenter study was designed to investigate the risk factors of decompensated tinnitus and to analyze the interaction effect of anxiety and poor sleep on dec... | Decompensated tinnitus; anxiety; interaction effect; risk factor; sleep | 0.493 | 93 | Otorhinolaryngology; Medicine | Medicine | 2,021 |
34,775,582 | Cesarean Birth Morbidity among Women with SARS-CoV-2. | American journal of perinatology | Am J Perinatol | 40 | 12 | 10.1055/s-0041-1739430 | eng | 2,023 | 9 | null | 2,021 | 11 | 14 | [OBJECTIVE] The objective of this study was to compare maternal outcomes of women with and without severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections who underwent cesarean births. [STUDY DESIGN] This was a matched cohort study of pregnant women who had a cesarean birth between March 15, 2020, and ... | null | 0.649 | 87 | Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health | Medicine | 2,023 |
34,775,527 | Single pharmacy governed denosumab home administration: optimal adherence by means of a fracture liaison service (FLS) and home care collaboration. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA | Osteoporos Int | 33 | 4 | 10.1007/s00198-021-06234-5 | eng | 2,022 | 4 | null | 2,021 | 11 | 13 | [UNLABELLED] Low adherence for denosumab (Dmab, Prolia®) is of major concern. Dutch pharmacies deliveries were calculated recently being 76.5% for a total of 3 injections. [INTRODUCTION] Comparing a model where the prescriber maintains responsibility for adherence (model HC1) (Dmab is purchased and dispensed by patient... | Denosumab; Fracture liaison service; Medication governance and continuation | 1.062 | 201 | Endocrinology, Diabetes and Metabolism; Medicine | Medicine | 2,022 |
34,775,247 | The impact of social factors, especially psychological worries on anxiety and depression in patients with epilepsy. | Epilepsy behavior : EB | Epilepsy Behav | 125 | null | 10.1016/j.yebeh.2021.108376 | eng | 2,021 | 12 | null | 2,021 | 11 | 12 | [BACKGROUND] Social factors are believed to affect mental health in patients with epilepsy (PWE). However, there is still a lack of sufficient manifest proof, given the difficulty of exposing PWE to relatively consistent natural social environments with a low or high level of social interaction to study their significa... | COVID-19; Clinical anxiety; Epilepsy; Major depression; Social variables | null | null | null | null | null |
34,775,181 | The Edmonton Symptom Assessment System: A narrative review of a standardized symptom assessment tool in head and neck oncology. | Oral oncology | Oral Oncol | 123 | null | 10.1016/j.oraloncology.2021.105595 | eng | 2,021 | 12 | null | 2,021 | 11 | 11 | [OBJECTIVE] Symptom burden is common in head and neck cancer patients though it frequently remains undetected and untreated. The Edmonton Symptom Assessment System - revised version (ESAS-r) is a generic symptom scale deployed in many outpatient settings worldwide. The ESAS-r is meant to improve symptom detection and m... | Dyspnea; Edmonton symptom assessment system; Fatigue; Head and neck cancer; Pain; Patient reported outcomes; Surveys and questionnaires; Symptom assessment | 1.421 | 143 | Cancer Research; Oncology; Oral Surgery | Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine | 2,021 |
34,775,180 | Clinical practice guidelines for dental management prior to radiation for head and neck cancer. | Oral oncology | Oral Oncol | 123 | null | 10.1016/j.oraloncology.2021.105604 | eng | 2,021 | 12 | null | 2,021 | 11 | 11 | [PURPOSE] Limited evidence exists linking the specific preventative dental care provided prior to radiation therapy (RT) for head and neck cancer to outcomes like osteoradionecrosis (ORN). This study utilized expert consensus to develop tooth-specific dental treatment pathways for head and neck cancer patients prior to... | Clinical Dental Guidelines; Clinical Practice Guidelines; Head and Neck Neoplasms; Osteoradionecrosis; Radiotherapy | 1.421 | 143 | Cancer Research; Oncology; Oral Surgery | Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine | 2,021 |
34,775,012 | Any Postoperative Surveillance Improves Survival after Endovascular Repair of Ruptured Abdominal Aortic Aneurysms. | Annals of vascular surgery | Ann Vasc Surg | 80 | null | 10.1016/j.avsg.2021.09.047 | eng | 2,022 | 3 | null | 2,021 | 11 | 12 | [BACKGROUND] Endovascular aortic repair (EVAR) has advanced the care of patients with ruptured abdominal aortic aneurysms (rAAA) with improved early postoperative morbidity and mortality. However, this comes at the cost of a rigorous postoperative surveillance schedule to monitor for further aneurysmal degeneration. Ad... | null | 0.65 | 87 | Cardiology and Cardiovascular Medicine; Medicine; Surgery | Medicine | 2,022 |
34,775,005 | "Uncontrolled" Hypertension Is Not an Independent Risk Factor for Adverse Short-Term Outcomes Following Total Joint Arthroplasty. | The Journal of arthroplasty | J Arthroplasty | 37 | 3 | 10.1016/j.arth.2021.11.014 | eng | 2,022 | 3 | null | 2,021 | 11 | 12 | [BACKGROUND] Uncontrolled hypertension (HTN) is a risk factor for mortality following elective surgery and poor hemodynamic control during total joint arthroplasty (TJA). However, the relationship between uncontrolled HTN and TJA outcomes remains poorly understood. The purpose of this study is to better define HTN para... | arthroplasty; complications; hip; hypertension; knee; optimization | 2.028 | 171 | Orthopedics and Sports Medicine | Medicine | 2,022 |
34,774,788 | Female reproductive factors and risk of joint replacement arthroplasty of the knee and hip due to osteoarthritis in postmenopausal women: a nationwide cohort study of 1.13 million women. | Osteoarthritis and cartilage | Osteoarthritis Cartilage | 30 | 1 | 10.1016/j.joca.2021.10.012 | eng | 2,022 | 1 | null | 2,021 | 11 | 10 | [OBJECTIVES] Previous studies of the relationships between female reproductive factors and osteoarthritis (OA) have shown conflicting results. In this study, we aimed to explore the relationships between reproductive factors and joint replacement arthroplasty of the knee (TKRA) and hip (THRA) in a large nationwide popu... | Epidemiology; Hip joint replacement; Knee joint replacement; Osteoarthritis; Reproductive history | 1.863 | 197 | Biomedical Engineering; Orthopedics and Sports Medicine; Rheumatology | Engineering; Medicine | 2,022 |
34,774,646 | The influence of diagnosed mental health conditions and symptoms of depression and/or anxiety on suicide ideation, plan, and attempt among college students: Findings from the Healthy Minds Study, 2018-2019. | Journal of affective disorders | J Affect Disord | 298 | Pt A | 10.1016/j.jad.2021.11.006 | eng | 2,022 | 2 | 1 | 2,021 | 11 | 10 | [BACKGROUND] Approximately 11% of 18-25 year-olds report thoughts of suicide. Additionally, suicide is the second leading cause of death in college student populations. We sought to evaluate the relationship between diagnosed mental health conditions and current symptoms of depression and/or anxiety and suicidality in ... | Abbreviations; Anxiety; College students; Depression; Mental health; Suicide attempted; Suicide ideation | 1.988 | 245 | Clinical Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,022 |
34,774,633 | Three exposure metrics of size-specific particulate matter associated with acute lower respiratory infection hospitalization in children: A multi-city time-series analysis in China. | The Science of the total environment | Sci Total Environ | 816 | null | 10.1016/j.scitotenv.2021.151636 | eng | 2,022 | 4 | 10 | 2,021 | 11 | 10 | [BACKGROUND] The global burden of acute lower respiratory infection (ALRI) attributable to air pollution has increased in recent years, but the association between ALRI and exposure to size-specific particulate matter has not been investigated using different exposure metrics. [METHODS] We obtained ALRI admission from ... | Acute lower respiratory infection; Air pollution; China; Particulate matter | 1.946 | 399 | Environmental Chemistry; Environmental Engineering; Pollution; Waste Management and Disposal | Environmental Science | 2,022 |
34,774,481 | Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer. | European urology oncology | Eur Urol Oncol | 5 | 2 | 10.1016/j.euo.2021.10.001 | eng | 2,022 | 4 | null | 2,021 | 11 | 11 | [BACKGROUND] No curative therapy is currently available for metastatic prostate cancer (PCa). The diverse mechanisms of progression include fibroblast growth factor (FGF) axis activation. [OBJECTIVE] To investigate the molecular and clinical implications of fibroblast growth factor receptor 1 (FGFR1) and its isoforms (... | Bone metastasis; Fibroblast growth factor receptor 1; Ladinin 1; Prostate cancer | 2.597 | 56 | Medicine; Oncology; Radiology, Nuclear Medicine and Imaging; Surgery; Urology | Medicine | 2,022 |
34,773,732 | Canonical babbling ratio - Concurrent and predictive evaluation of the 0.15 criterion. | Journal of communication disorders | J Commun Disord | 94 | null | 10.1016/j.jcomdis.2021.106164 | eng | 2,021 | null | null | 2,021 | 11 | 10 | [INTRODUCTION] Canonical babbling ratio (CBR) is a commonly used measure to quantify canonical babbling (CB), and 0.15 is the commonly accepted criterion for the canonical babbling stage. However, this has not been thoroughly investigated. The aim of this study was to evaluate the validity of this criterion using concu... | CBR; Infant vocalizations; Observation method; Percentage of consonants correct; Validity; Vocabulary | 0.634 | 79 | Linguistics and Language; LPN and LVN; Experimental and Cognitive Psychology; Speech and Hearing; Cognitive Neuroscience | Health Professions; Neuroscience; Nursing; Psychology; Social Sciences | 2,021 |
34,773,519 | The clinical impact of frailty on the postoperative outcomes of patients undergoing gastrectomy for gastric cancer: a propensity-score matched database study. | Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association | Gastric Cancer | 25 | 2 | 10.1007/s10120-021-01265-7 | eng | 2,022 | 3 | null | 2,021 | 11 | 13 | [BACKGROUND] Frailty aggregates a composite of geriatric and elderly features that is classified into a singular syndrome; literature thus far has proven its influence over postoperative outcomes. In this study, we evaluate the effects of frailty following gastrectomy for gastric cancer. [METHODS] 2011-2017 National In... | Frailty-defining features; Gastric malignancy; Gastric resection; Johns Hopkins ACG frailty | 2.118 | 106 | Cancer Research; Gastroenterology; Medicine; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,773,494 | Resection and reconstruction with and without neoadjuvant denosumab in campanacci grade III giant cell tumors of proximal humerus: a retrospective comparative study. | European journal of orthopaedic surgery traumatology : orthopedie traumatologie | Eur J Orthop Surg Traumatol | 33 | 1 | 10.1007/s00590-021-03162-2 | eng | 2,023 | 1 | null | 2,021 | 11 | 13 | [BACKGROUND] Giant cell tumors (GCT) of the proximal humerus are rarely reported case that requires complex surgeries due to involvement of the shoulder joint. Therefore, we report the first retrospective comparative study where the postoperative functional outcomes, recurrence rate and complications in patients who un... | Bone tumors; Denosumab; Giant cell tumor; Resection and reconstruction | null | null | null | null | null |
34,773,431 | Outcomes during the first year following spontaneous coronary artery dissection: A systematic timeframe pooled analysis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography Interventions | Catheter Cardiovasc Interv | 99 | 2 | 10.1002/ccd.30016 | eng | 2,022 | 2 | null | 2,021 | 11 | 13 | [OBJECTIVES] We aimed to compare the incidence and timing of major adverse cardiovascular events (MACE) within the first year after spontaneous coronary artery dissection (SCAD) according to the management strategy: conservative versus invasive. [BACKGROUND] Treatment of SCAD remains controversial. [METHODS] A pooled a... | acute myocardial infarction; coronary artery disease; percutaneous coronary intervention | 0.964 | 134 | Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,022 |
34,773,262 | Characterizing demographics and cost of care for dyshidrotic eczema. | Contact dermatitis | Contact Dermatitis | 86 | 2 | 10.1111/cod.14007 | eng | 2,022 | 2 | null | 2,021 | 12 | 5 | [BACKGROUND] Dyshidrotic eczema (DE) is a common form of eczema affecting the hands, feet, or both areas. To date, there has been little research examining demographics and cost burden associated with this disease. [OBJECTIVE] This study seeks to characterize the demographics of patients affected and the direct costs o... | allergic contact dermatitis; atopic dermatitis; occupational | 0.72 | 112 | Dermatology; Immunology and Allergy | Medicine | 2,022 |
34,773,167 | Pretreatment tumor sampling and prognostic factors in patients with soft-tissue sarcoma of the head and neck. | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery | Eur Arch Otorhinolaryngol | 279 | 6 | 10.1007/s00405-021-07162-0 | eng | 2,022 | 6 | null | 2,021 | 11 | 12 | [BACKGROUND] Insufficient preoperative work-up and consequent intralesional or marginal resection of soft-tissue sarcomas of the head and neck (STSHNs) is common. [METHODS] This retrospective cohort study comprised 63 patients with STSHN treated at the Helsinki University Hospital between 2005 and 2017. We assessed the... | Head and neck sarcoma; Pretreatment work-up; Prognostic factors; Single-center experience; Survival | 0.857 | 94 | Otorhinolaryngology; Medicine | Medicine | 2,022 |
34,772,408 | Informed consent in psychotherapy: a survey on attitudes among psychotherapists in Switzerland. | BMC medical ethics | BMC Med Ethics | 22 | 1 | 10.1186/s12910-021-00718-z | eng | 2,021 | 11 | 12 | 2,021 | 11 | 12 | [BACKGROUND] The legal and ethical guidelines of psychological professional associations stipulate that informed consent by patients is an essential prerequisite for psychotherapy. Despite this awareness of the importance of informed consent, there is little empirical evidence on what psychotherapists' attitudes toward... | Autonomy; Ethics; Expectations; Informed consent; Paternalism; Psychotherapy | 0.832 | 66 | Health Policy; Health; Issues, Ethics and Legal Aspects | Medicine; Nursing; Social Sciences | 2,021 |
34,772,397 | Effects of 45S5 bioactive glass on the remineralization of early carious lesions in deciduous teeth: an in vitro study. | BMC oral health | BMC Oral Health | 21 | 1 | 10.1186/s12903-021-01931-3 | eng | 2,021 | 11 | 12 | 2,021 | 11 | 12 | [BACKGROUND] Early childhood caries has been designated as a serious public health problem. The traditional restoration method is very challenging, especially in uncooperative patients. Non-invasive therapy, like remineralization agents, which have been developed to reverse the demineralization progress at the early st... | Bioactive glass; Deciduous teeth; Energy dispersive X-ray spectroscopy; Remineralization | 0.79 | 80 | Dentistry | Dentistry | 2,021 |
34,772,360 | Risk factors for the frequent attendance of older patients at community health service centers in China: a cross-sectional study based on stratified sampling. | BMC family practice | BMC Fam Pract | 22 | 1 | 10.1186/s12875-021-01575-w | eng | 2,021 | 11 | 12 | 2,021 | 11 | 12 | [BACKGROUND] This study aimed to investigate the characteristics of frequent attenders (FAs) among older patients in Shanghai, China, and explore the associated factors. [METHODS] This cross-sectional study was conducted in six community health service centers in Shanghai, China, from August to December 2018 based on s... | China; Community health service center; Frequent attendance; Frequent attender; Older patient | 0.836 | 0 | Family Practice | Medicine | 2,021 |
34,772,347 | Clinical outcomes in 2481 unselected real-world patients treated with a polymer-free sirolimus-eluting stent: 3 years results from the NANO multicenter Registry. | BMC cardiovascular disorders | BMC Cardiovasc Disord | 21 | 1 | 10.1186/s12872-021-02356-0 | eng | 2,021 | 11 | 12 | 2,021 | 11 | 12 | [OBJECTIVES] To evaluate the 3-year clinical outcomes of a polymer-free sirolimus-eluting, Nano plus stent for the treatment of coronary artery disease in the NANO multicenter Registry. [BACKGROUND] The long-term clinical data evaluating the safety and efficacy of the novel polymer-free sirolimus-eluting Nano plus sten... | Percutaneous coronary interventions; Polymer-free drug-eluting stent; Real-world population; Target lesion failure | 0.675 | 76 | Cardiology and Cardiovascular Medicine | Medicine | 2,021 |
34,770,170 | A Structural Equation Modelling Approach to Determine Factors of Bone Mineral Density in Korean Women. | International journal of environmental research and public health | Int J Environ Res Public Health | 18 | 21 | 10.3390/ijerph182111658 | eng | 2,021 | 11 | 6 | 2,021 | 11 | 6 | [BACKGROUND] no studies have assessed the associations of nutrient intake, physical activity, age, and body mass index (BMI) with bone mineral density (BMD) using structural equation modelling (SEM) in Korean women. The aim of this study was to examine the effects of nutrient intakes, physical activity, and body mass i... | bone mineral density; nutrient intake; premenopausal women and postmenopausal women; structural equation modelling | 0.814 | 229 | Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health | Environmental Science; Medicine | 2,021 |
34,769,987 | Contents of the Sexual and Reproductive Health Subject in the Undergraduate Nursing Curricula of Spanish Universities: A Cross-Sectional Study. | International journal of environmental research and public health | Int J Environ Res Public Health | 18 | 21 | 10.3390/ijerph182111472 | eng | 2,021 | 10 | 31 | 2,021 | 10 | 31 | [BACKGROUND] Nursing students must receive adequate training in Sexual and Reproductive Health (SRH), which could allow them to acquire sufficient knowledge to solve the future SRH needs of everyone. In this study, the contents of the SRH subject in the undergraduate nursing curricula of 77 Spanish universities were ex... | comprehensive sexuality education; gender equality; nursing curriculum; nursing education; reproductive health; sexual health; sexual rights; undergraduate education | 0.814 | 229 | Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health | Environmental Science; Medicine | 2,021 |
34,768,732 | Variability in Oral Iron Prescription and the Effect on Spanish Mothers' Health: A Prospective Longitudinal Study. | Journal of clinical medicine | J Clin Med | 10 | 21 | 10.3390/jcm10215212 | eng | 2,021 | 11 | 8 | 2,021 | 11 | 8 | [BACKGROUND] No consensus exists regarding the hemoglobin (Hb) values that define postpartum anemia. Knowledge is currently lacking regarding prescription and consumption practices, which prevents evaluating the rational use of iron supplementation postpartum. [AIM] In this study, our objective was to describe this pra... | anemia; gynecology; iron; medicine; prescription | 1.04 | 132 | Medicine | Medicine | 2,021 |
34,768,708 | Prevalence and Causes of Myocardial Infarction with Non-Obstructive Coronary Arteries in a Contemporary Cohort of Patients with Suspected Myocardial Infarction. | Journal of clinical medicine | J Clin Med | 10 | 21 | 10.3390/jcm10215188 | eng | 2,021 | 11 | 6 | 2,021 | 11 | 6 | [BACKGROUND] A significant proportion of patients presenting with acute myocardial infarction (MI) has no coronary obstruction at coronary angiography and no other obvious non-coronary pathophysiology causing MI. These patients are classified as MI with non-obstructive coronary arteries (MINOCA). Data on incidence and ... | MINOCA; myocardial infarction; non-obstructive coronary arteries; predictors | 1.04 | 132 | Medicine | Medicine | 2,021 |
34,768,563 | Immediate Effects of Kinesio Taping on Rectus Abdominis Diastasis in Postpartum Women-Preliminary Report. | Journal of clinical medicine | J Clin Med | 10 | 21 | 10.3390/jcm10215043 | eng | 2,021 | 10 | 28 | 2,021 | 10 | 28 | [BACKGROUND] Rectus abdominis diastasis (RAD) is an excessive divarication of the rectus abdominis muscle with concurrent stretching and thinning of the linea alba, which occurs due to mechanical and functional disturbances in the anterior abdominal wall and the whole body. The primary objective of this study is a palp... | kinesio taping; postpartum women; rectus abdominis diastasis; surface electromyography | 1.04 | 132 | Medicine | Medicine | 2,021 |
34,768,516 | A Prospective, Single Arm, Multi-Center Study Evaluating the Clinical Outcomes of Ventral Hernias Treated with OviTex[®] 1S Permanent Reinforced Tissue Matrix: The BRAVO Study 12-Month Analysis. | Journal of clinical medicine | J Clin Med | 10 | 21 | 10.3390/jcm10214998 | eng | 2,021 | 10 | 27 | 2,021 | 10 | 27 | [BACKGROUND] Conflicting results from previous studies have led to dissent over whether surgical mesh is safe and effective in ventral hernia repair. A newer class of mesh known as a reinforced tissue matrix, combining a biologic scaffold and minimal polymer reinforcement, offers promise in reducing inflammatory respon... | decellularized extracellular matrix; recurrence; reinforced tissue matrix; ventral hernia repair | 1.04 | 132 | Medicine | Medicine | 2,021 |
34,768,448 | Allografts for Skin Closure during In Utero Spina Bifida Repair in a Sheep Model. | Journal of clinical medicine | J Clin Med | 10 | 21 | 10.3390/jcm10214928 | eng | 2,021 | 10 | 25 | 2,021 | 10 | 25 | [OBJECTIVES] Use of off-label tissue graft materials, such as acellular dermal matrix (ADM), for in utero repair of severe spina bifida (SB), where primary skin layer closure is not possible, is associated with poor neurological outcomes. The cryopreserved human umbilical cord (HUC) patch has regenerative, anti-inflamm... | acellular dermal matrix; astrocyte activation; conventional repair; inflammation; regenerative healing; sheep spina bifida repair model; umbilical cord | 1.04 | 132 | Medicine | Medicine | 2,021 |
34,768,176 | β-lactam dosing at the early phase of sepsis: Performance of a pragmatic protocol for target concentration achievement in a prospective cohort study. | Journal of critical care | J Crit Care | 67 | null | 10.1016/j.jcrc.2021.10.023 | eng | 2,022 | 2 | null | 2,021 | 11 | 9 | [PURPOSE] We hypothesized that a protocol of standardized fixed dose using prolonged infusion during the early phase of sepsis may avoid insufficient β-lactam concentrations. [METHODS] In this single center prospective study, patients with sepsis and vasopressors were enrolled if they were treated by either piperacilli... | Pharmacokinetic; Sepsis | 1.085 | 109 | Critical Care and Intensive Care Medicine | Medicine | 2,022 |
34,768,124 | Correlates of days of medication for opioid use disorder exposure among people living with HIV in Northern Vietnam. | The International journal on drug policy | Int J Drug Policy | 100 | null | 10.1016/j.drugpo.2021.103503 | eng | 2,022 | 2 | null | 2,021 | 11 | 9 | [BACKGROUND] In Vietnam, access to medications for opioid use disorder (MOUD) for people living with HIV has rapidly expanded, but MOUD use over time remains low. We sought to assess factors associated with days of MOUD treatment exposure. [METHODS] From 2015 to 2019, patients with OUD in six Northern Vietnamese HIV cl... | Buprenorphine; HIV; Methadone; Opioid-related disorders; Retention in care; Vietnam | null | null | null | null | null |
34,768,016 | E-learning versus face-to-face training: Comparison of two learning methods for Lyme borreliosis. | Infectious diseases now | Infect Dis Now | 52 | 1 | 10.1016/j.idnow.2021.11.001 | eng | 2,022 | 2 | null | 2,021 | 11 | 9 | [OBJECTIVES] To compare two learning methods for Lyme disease (e-learning versus face-to-face training) to assess knowledge and know-how. [METHODS] The study population was volunteer general medicine residents and family physicians (FP). Face-to-face training on Lyme disease was offered to each group. E-learning traini... | E-learning; General medicine; Lyme; Script concordance test | 0.712 | 54 | Infectious Diseases | Medicine | 2,022 |
34,767,482 | Prostate-specific membrane antigen (PSMA) fusion imaging in prostate cancer: PET-CT vs PET-MRI. | The British journal of radiology | Br J Radiol | 95 | 1131 | 10.1259/bjr.20210728 | eng | 2,022 | 3 | 1 | 2,021 | 12 | 21 | [OBJECTIVES] To investigate whether PET-CT or PET-MRI is more appropriate for imaging prostate cancer, in terms of primary tumor detection, local staging and recurrence, as well as lymph nodes and distant metastases. [METHODS] A systematic literature search was conducted on Embase, PubMed/MEDLINE, and the Cochrane Libr... | null | 0.757 | 128 | Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,022 |
34,767,149 | Randomized trial of high-dose rectal diclofenac suppository and epinephrine spray on duodenal papilla for prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis. | Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology | Indian J Gastroenterol | 40 | 5 | 10.1007/s12664-021-01161-z | eng | 2,021 | 10 | null | 2,021 | 11 | 12 | [BACKGROUND AND AIMS] High-dose rectal diclofenac suppository and epinephrine spray on duodenal papilla during endoscopic retrograde cholangiopancreatography (ERCP) may reduce the incidence of post-ERCP pancreatitis. We performed randomized trial to compare the effect of combination of rectal diclofenac and epinephrine... | Acute pancreatitis; Duodenal papilla; Endoscopic retrograde cholangiopancreatography; Epinephrine; Gastrointestinal bleeding | 0.563 | 49 | Gastroenterology | Medicine | 2,021 |
34,767,146 | Residential distance from the reporting hospital and survival among adolescents, and young adults diagnosed with CNS tumors. | Journal of neuro-oncology | J Neurooncol | 155 | 3 | 10.1007/s11060-021-03885-6 | eng | 2,021 | 12 | null | 2,021 | 11 | 12 | [PURPOSE] Prior research shows that residential distance to a treatment facility may be an important factor in central nervous system (CNS) tumor outcomes. Our goal was to examine residential distance to the reporting hospital and overall survival in adolescents and young adults (AYA) diagnosed with CNS tumors. [METHOD... | Adolescents and young adults; CNS tumors; Survival; Travel distance | 1.022 | 141 | Neurology; Cancer Research; Neurology; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience | 2,021 |
34,766,917 | Improvements in Diet and Physical Activity-Related Psychosocial Factors Among African Americans Using a Mobile Health Lifestyle Intervention to Promote Cardiovascular Health: The FAITH! (Fostering African American Improvement in Total Health) App Pilot Study. | JMIR mHealth and uHealth | JMIR Mhealth Uhealth | 9 | 11 | 10.2196/28024 | eng | 2,021 | 11 | 12 | 2,021 | 11 | 12 | [BACKGROUND] African Americans continue to have suboptimal cardiovascular health (CVH) related to diet and physical activity (PA) behaviors compared with White people. Mobile health (mHealth) interventions are innovative platforms to improve diet and PA and have the potential to mitigate these disparities. However, the... | African Americans; cardiovascular health disparities; diet; mHealth lifestyle intervention; mobile phone; physical activity | 1.362 | 107 | Health Informatics | Medicine | 2,021 |
34,766,846 | Perceived mattering in the face of COVID-19: links with emotion regulation and psychological well-being. | Psychology health | Psychol Health | 37 | 12 | 10.1080/08870446.2021.2002860 | eng | 2,022 | 12 | null | 2,021 | 11 | 12 | [OBJECTIVE] The present study aimed to examine the protective role of perceived mattering to family and friends on psychological well-being in the Italian context during the COVID-19 pandemic, considering the mediating role of emotion regulation. [DESIGN] Data were collected during the first lockdown (March-April, 2020... | null | null | null | null | null | null |
34,766,662 | Genetic variants of PON1, GSTM1, GSTT1, and locus 9p21.3, and the risk for premature coronary artery disease in Yucatan, Mexico. | American journal of human biology : the official journal of the Human Biology Council | Am J Hum Biol | 34 | 5 | 10.1002/ajhb.23701 | eng | 2,022 | 5 | null | 2,021 | 11 | 12 | [OBJECTIVE] Genetic variants of PON1, rs70587, rs662, rs854560, GSTM1, and GSTT1 and two single nucleotide polymorphisms (SNP) at 9p21.3 locus, rs1333049, and rs2383207; were evaluated in association with the risk for premature coronary artery disease (CAD) in a population of Yucatan, Mexico. These genes are involved i... | null | 0.744 | 97 | Anatomy; Anthropology; Ecology, Evolution, Behavior and Systematics; Genetics | Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Social Sciences | 2,022 |
34,766,194 | Emergency Neurosurgery Performed by General Surgeons: A Systematic Review. | World journal of surgery | World J Surg | 46 | 2 | 10.1007/s00268-021-06363-2 | eng | 2,022 | 2 | null | 2,021 | 11 | 11 | [BACKGROUND] In under-resourced settings, general surgeons may be called upon to perform emergency operations within other specialties. Accordingly, we aimed to characterise patient outcomes after emergency neurosurgery performed by a general surgeon or general surgery trainee. [METHODS] PubMed, Embase and the Cochrane... | null | 0.902 | 176 | Surgery | Medicine | 2,022 |
34,766,067 | In-hospital cardiac arrest due to pulmonary embolism - Treatment and outcomes in a Swedish cohort study. | Resuscitation plus | Resusc Plus | 8 | null | 10.1016/j.resplu.2021.100178 | eng | 2,021 | 12 | null | 2,021 | 11 | 1 | [OBJECTIVES] Pulmonary embolism (PE) constitutes one of the reversible causes of cardiac arrest. The prognosis for PE-related cardiac arrest is poor. Some previous studies have suggested a higher survival rate in patients with PE-related cardiac arrest who receive thrombolysis. No such study has focused on in-hospital ... | IHCA; PE; Thrombolysis | null | 20 | Cardiology and Cardiovascular Medicine; Emergency Medicine; Emergency Nursing | Medicine; Nursing | 2,021 |
34,765,824 | The Correlation between Hypertropia and Head Tilt in Congenital Unilateral Superior Oblique Muscle Palsy. | Journal of current ophthalmology | J Curr Ophthalmol | 33 | 3 | 10.4103/joco.joco_60_20 | eng | 2,021 | null | null | 2,021 | 10 | 22 | [PURPOSE] To evaluate the correlation between the angle of deviation in different gazes and the amount of head tilt in patients with congenital unilateral superior oblique muscle palsy (SOP). [METHODS] This case series study was performed on 20 consecutive SOP patients with head tilt. Based on the Bielschowsky three-st... | Abnormal head position; Head tilt; Hypertropia; Superior oblique palsy | 0.765 | 32 | Ophthalmology | Medicine | 2,021 |
34,765,733 | A Case of Glucocorticoid Hypersensitivity Syndrome Associated With Underlying Rubella Virus Infection. | AACE clinical case reports | AACE Clin Case Rep | 7 | 6 | 10.1016/j.aace.2021.06.010 | eng | 2,021 | null | null | 2,021 | 6 | 23 | [OBJECTIVE] The objective of this article is to report a rare case of glucocorticoid hypersensitivity syndrome, which may be associated with an underlying rubella virus infection. [CASE REPORT] A 29-year-old man showed progressive weight gain for 16 months accompanied by a moon face, enlarged dorsocervical fat pad, cen... | Cushing syndrome; ESR, erythrocyte sedimentation rate; HPA, hypothalamic-pituitary-adrenal; case report; glucocorticoid hypersensitivity; hGR, human glucocorticoid receptor; hypocortisolemia; rubella virus | null | 15 | Endocrinology, Diabetes and Metabolism | Medicine | 2,021 |
34,765,720 | Long-Term renal function after implantation of continuous-flow left ventricular assist devices: A single center study. | International journal of cardiology. Heart vasculature | Int J Cardiol Heart Vasc | 37 | null | 10.1016/j.ijcha.2021.100907 | eng | 2,021 | 12 | null | 2,021 | 11 | 1 | [BACKGROUND] Implantable continuous-flow left ventricular assist device (LVAD) improve renal function in advanced heart failure. However, the long-term effects of LVAD on renal function have not been investigated thoroughly. We aimed to assess long-term renal function in patients with LVAD support and to identify predi... | Left ventricular assist devices; Renal function; Right ventricular failure | null | null | null | null | null |
34,765,676 | Epidemiological Characteristics and Drug Resistance of Fungemia in General Hospitals from 2010 to 2019. | BioMed research international | Biomed Res Int | 2021 | null | 10.1155/2021/2529171 | eng | 2,021 | null | null | 2,021 | 11 | 2 | [OBJECTIVE] This study intends to analyze the data of fungemia in a large tertiary hospital from 2010 to 2019, and is aimed at understanding its epidemic characteristics and drug resistance. [METHODS] The "Hospital Infection Real-Time Monitoring System" was used to retrieve the case information of patients who were hos... | null | 0.647 | 203 | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,021 |
34,765,542 | Deep Learning Radiomics to Predict Regional Lymph Node Staging for Hilar Cholangiocarcinoma. | Frontiers in oncology | Front Oncol | 11 | null | 10.3389/fonc.2021.721460 | eng | 2,021 | null | null | 2,021 | 10 | 26 | [BACKGROUND] Our aim was to establish a deep learning radiomics method to preoperatively evaluate regional lymph node (LN) staging for hilar cholangiocarcinoma (HC) patients. [METHODS AND MATERIALS] Of the 179 enrolled HC patients, 90 were pathologically diagnosed with lymph node metastasis. Quantitative radiomic featu... | computed tomography; deep learning; hilar cholangiocarcinoma; lymph node; radiomics | 1.291 | 156 | Oncology; Cancer Research | Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
34,765,461 | Combined vesicouterine rupture during second-trimester medical abortion for fetal abnormality after prior cesarean delivery: A case report. | Case reports in women's health | Case Rep Womens Health | 32 | null | 10.1016/j.crwh.2021.e00364 | eng | 2,021 | 10 | null | 2,021 | 10 | 27 | [INTRODUCTION] The use of mifepristone and misoprostol for the induction of a second-trimester abortion is common and effective. However, its safety in women with previous cesarean delivery is still controversial, given the potentially higher risk of uterine rupture. [CASE PRESENTATION] We present the case of a 30-year... | Bladder rupture; Mifepristone; Misoprostol; Second-trimester abortion; Uterine rupture | null | null | null | null | null |
34,765,359 | Detection of Autosomal Dominant Polycystic Kidney Disease by Medical Checkup at an Early Stage. | Cureus | Cureus | 13 | 10 | 10.7759/cureus.18595 | eng | 2,021 | 10 | null | 2,021 | 10 | 8 | [INTRODUCTION] Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disease. Although abdominal echography during medical checkup may be effective for the early detection of ADPKD, there are no reports of the early detection of ADPKD during medical checkup. We investigated whether the... | adpkd; ckd; medical checkup; renal prognosis; tolvaptan | null | null | null | null | null |
34,765,261 | Long-Term Outcome of Eyes with Vitrectomy for Submacular and/or Vitreous Hemorrhage in Neovascular Age-Related Macular Degeneration. | Journal of ophthalmology | J Ophthalmol | 2021 | null | 10.1155/2021/2963822 | eng | 2,021 | null | null | 2,021 | 11 | 2 | [PURPOSE] To study long-term clinical outcomes in patients with submacular hemorrhage (SMH) and/or vitreous hemorrhage (VH) associated with neovascular age-related macular degeneration (nAMD) and the real-world clinical situation of adding anti-VEGF therapy after pars plana vitrectomy (PPV). [METHODS] In this retrospec... | null | 0.744 | 65 | Ophthalmology | Medicine | 2,021 |
34,765,118 | 30 Years of postdisturbance recruitment in a Neotropical forest. | Ecology and evolution | Ecol Evol | 11 | 21 | 10.1002/ece3.7634 | eng | 2,021 | 11 | null | 2,021 | 10 | 7 | [QUESTIONS] Long-term community response to disturbance can follow manifold successional pathways depending on the interplay between various recruitment processes. Analyzing the succession of recruited communities provides a long-term perspective on forest response to disturbance. Specifically, postdisturbance recruitm... | Neotropical forests; community composition; community diversity; disturbance response; functional trait; postdisturbance recovery; recruitment; successional pathway; taxonomy; tree community | null | null | null | null | null |
34,824,137 | Patient and public engagement in decision-making regarding infectious disease outbreak management: an integrative review. | BMJ global health | BMJ Glob Health | 6 | 11 | 10.1136/bmjgh-2021-007340 | eng | 2,021 | 11 | null | null | null | null | [INTRODUCTION] Worldwide, people experience the effects of infectious disease outbreaks on a regular basis. These effects vary from direct impact of the virus on health, to indirect impact of control measures on day-to-day life. Yet, incorporating the experiences, views and ideas of patients and the public in decision-... | control strategies; diseases; disorders; health policy; infections; injuries; review | 2.263 | 91 | Health Policy; Public Health, Environmental and Occupational Health | Medicine | 2,021 |
34,823,919 | International survey on opinions and use of minimally invasive surgery in small bowel neuroendocrine neoplasms. | European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology | Eur J Surg Oncol | 48 | 6 | 10.1016/j.ejso.2021.11.011 | eng | 2,022 | 6 | null | 2,021 | 11 | 18 | [INTRODUCTION] Although minimally invasive surgery is becoming the standard technique in gastrointestinal surgery, implementation for small bowel neuroendocrine neoplasms (SB-NEN) is lagging behind. The aim of this international survey was to gain insights into attitudes towards minimally invasive surgery for resection... | Minimally invasive surgery; Neuroendocrine neoplasms; Survey | 1.097 | 123 | Medicine; Surgery; Oncology | Medicine | 2,022 |
34,823,523 | Prediction of the CYP2D6 enzymatic activity based on investigating of the CYP2D6 genotypes around the vivax malaria patients in Yunnan Province, China. | Malaria journal | Malar J | 20 | 1 | 10.1186/s12936-021-03988-5 | eng | 2,021 | 11 | 25 | 2,021 | 11 | 25 | [BACKGROUND] In recent years, the incidence rate of vivax malaria recurrence still had 3.1% in Yunnan Province population after eradication therapy using primaquine (PQ). In order to understand the specific failure reasons for preventing vivax malaria relapses, a preliminary exploration on the CYP2D6 enzyme activity wa... | CYP2D6; Enzyme activity; Genotype; Prediction; Vivax malaria patient; Yunnan Province | 1.307 | 126 | Infectious Diseases; Parasitology | Immunology and Microbiology; Medicine | 2,021 |
34,823,266 | Genetic Evidence for Congenital Vascular Disorders in Patients with VACTERL Association. | European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie | Eur J Pediatr Surg | 32 | 1 | 10.1055/s-0041-1739423 | eng | 2,022 | 2 | null | 2,021 | 11 | 25 | [INTRODUCTION] The VACTERL association is a rare malformation complex, showing at least three anomalies of the following organ systems: vertebra, anorectum, heart and vessels, trachea and esophagus, genitourinary tract, and limbs. In addition to a multifactorial event, congenital vascular disorders are also discussed a... | null | 0.552 | 58 | Pediatrics, Perinatology and Child Health; Surgery | Medicine | 2,022 |
34,823,194 | Implementation and evaluation of sepsis surveillance and decision support in medical ICU and emergency department. | The American journal of emergency medicine | Am J Emerg Med | 51 | null | 10.1016/j.ajem.2021.09.086 | eng | 2,022 | 1 | null | 2,021 | 11 | 11 | [OBJECTIVE] To improve the timely diagnosis and treatment of sepsis many institutions implemented automated sepsis alerts. Poor specificity, time delays, and a lack of actionable information lead to limited adoption by bedside clinicians and no change in practice or clinical outcomes. We aimed to compare sepsis care co... | Data display; Informatics; Information technology; Sepsis; Shock; Surveillance | 0.88 | 114 | Emergency Medicine; Medicine | Medicine | 2,022 |
34,823,161 | Mechanisms of Change in Trauma-Focused Treatment for PTSD: The Role of Rumination. | Behaviour research and therapy | Behav Res Ther | 148 | null | 10.1016/j.brat.2021.104009 | eng | 2,022 | 1 | null | 2,021 | 11 | 19 | [OBJECTIVE] Cognitive behavioral therapy (CBT) has been well established in the treatment of posttraumatic stress disorder (PTSD). In recent years, researchers have begun to investigate its underlying mechanisms of change. Dysfunctional cognitive content, i.e. excessively negative appraisals of the trauma or its conseq... | Mechanisms of change; PTSD; Trauma-focused treatment; rumination | 1.787 | 222 | Clinical Psychology; Developmental and Educational Psychology; Experimental and Cognitive Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,022 |
34,823,035 | Long-term outcomes of photodynamic therapy for a positive resection margin after conization for cervical intraepithelial neoplasia grade 3. | Photodiagnosis and photodynamic therapy | Photodiagnosis Photodyn Ther | 37 | null | 10.1016/j.pdpdt.2021.102639 | eng | 2,022 | 3 | null | 2,021 | 11 | 22 | [BACKGROUND] Positive resection margins after conization or loop electrosurgical excision procedure (conization/LEEP) are associated with increased risks of recurrence or residual cervical intraepithelial neoplasia (CIN). Herein, we investigated the long-term outcomes of photodynamic therapy (PDT) for incomplete excisi... | Cervical intraepithelial neoplasia; Conization; Margins of excision; Photodynamic therapy | 0.633 | 73 | Biophysics; Dermatology; Pharmacology; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,822,999 | Does Prophylactic Paraortic Lymph Node Irradiation Improve Outcomes in Women With Stage IIIC1 Endometrial Carcinoma? | Practical radiation oncology | Pract Radiat Oncol | 12 | 2 | 10.1016/j.prro.2021.10.002 | eng | 2,022 | null | null | 2,021 | 11 | 23 | [PURPOSE] To evaluate the impact of prophylactic paraortic lymph node (PALN) radiation therapy (RT) on clinical outcomes in patients with International Federation of Obstetrics and Gynecology 2018 stage IIIC1 endometrial cancer (EC). [METHODS AND MATERIALS] A multi-institutional retrospective study included patients wi... | null | 0.847 | 57 | Radiology, Nuclear Medicine and Imaging; Oncology | Medicine | 2,022 |
34,822,754 | Increased Osteogenic Activity of Dynamic Cultured Composite Bone Scaffolds: Characterization and In Vitro Study. | Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons | J Oral Maxillofac Surg | 80 | 2 | 10.1016/j.joms.2021.10.011 | eng | 2,022 | 2 | null | 2,021 | 10 | 27 | [PURPOSE] The purpose of this study was to develop and characterize beta-tricalcium phosphate (β-TCP)/polycaprolactone (PCL) scaffolds, with 2 different ratios (50/50% and 65/35%), using 3-dimensionally (3D) printed dissolvable molds, and to evaluate cellular growth and osteogenic differentiation of both groups seeded ... | null | 0.649 | 147 | Oral Surgery; Otorhinolaryngology; Surgery | Dentistry; Medicine | 2,022 |
34,822,742 | Diagnosis of idiopathic intracranial hypertension - the importance of excluding secondary causes: A systematic review. | Cephalalgia : an international journal of headache | Cephalalgia | 42 | 6 | 10.1177/03331024211056580 | eng | 2,022 | 5 | null | 2,021 | 11 | 25 | [BACKGROUND] Idiopathic intracranial hypertension is characterized by increased intracranial pressure without any pathological findings on neuroimaging, except for signs of high intracranial pressure. Before diagnosing idiopathic intracranial hypertension secondary causes of increased intracranial pressure should be ex... | Secondary intracranial hypertension; body mass index; obesity; overweight; phenotype; risk factors | 1.561 | 148 | Medicine; Neurology | Medicine | 2,022 |
34,820,966 | Campylobacter concisus gastritis masquerading as Helicobacter pylori on gastric biopsy. | Helicobacter | Helicobacter | 27 | 2 | 10.1111/hel.12864 | eng | 2,022 | 4 | null | 2,021 | 11 | 24 | [OBJECTIVE] Campylobacter concisus is a Gram-negative rod closely related to Helicobacter pylori. We sought to identify gastric biopsies positive for C. concisus that had been misdiagnosed as H. pylori gastritis in our routine surgical pathology practice. [MATERIALS AND METHODS] We performed a retrospective review of g... | Campylobacter concisus; Helicobacter pylori diagnosis; gastritis; gastroscopic biopsy; histopathology; immunohistochemistry | 1.29 | 94 | Gastroenterology; Infectious Diseases; Medicine | Medicine | 2,022 |
34,820,920 | The impact of the complexing agent on the sensitivity of collision-induced dissociation spectra to fatty acid position for a set of XYZ-type triglycerides. | Rapid communications in mass spectrometry : RCM | Rapid Commun Mass Spectrom | 36 | 4 | 10.1002/rcm.9226 | eng | 2,022 | 2 | 28 | null | null | null | [RATIONALE] The development of an automated platform for the positional analysis of triglycerides (TAGs) based on electrospray ionization tandem mass spectrometry (ESI-MS/MS) continues to be pursued. This work evaluates the positional sensitivities of the collision-induced dissociation (CID) spectra of a representative... | null | 0.423 | 152 | Analytical Chemistry; Organic Chemistry; Spectroscopy | Chemistry | 2,022 |
34,820,784 | Are Medical Devices Cost-Effective? | Applied health economics and health policy | Appl Health Econ Health Policy | 20 | 2 | 10.1007/s40258-021-00698-6 | eng | 2,022 | 3 | null | 2,021 | 11 | 25 | [OBJECTIVE] Medical devices can offer important therapeutic advances but, as for any medical interventions, there are questions about their costs and benefits. We examined health benefits and costs for pre-market approved (PMA) devices approved by the US Food and Drug Administration (FDA) (1999-2015), grouping them by ... | null | 1.017 | 56 | Health Policy; Medicine; Economics and Econometrics | Economics, Econometrics and Finance; Medicine | 2,022 |
34,820,724 | The effects of connective tissue graft position on clinical and aesthetical outcomes of gingival recession treatment: a controlled randomized clinical trial. | Clinical oral investigations | Clin Oral Investig | 26 | 3 | 10.1007/s00784-021-04250-7 | eng | 2,022 | 3 | null | 2,021 | 11 | 24 | [OBJECTIVES] This randomized controlled clinical trial with 1-year follow-up compared the clinical and aesthetic results of coronally advanced flap (CAF) + connective tissue graft (CTG) positioned apical to the cemento-enamel junction (CEJ) (CAF + CTG-ACEJ) with CAF + CTG positioned on the CEJ (CAF + CTG-CEJ) for treat... | Aesthetical evaluation; Connective tissue graft; Root coverage | 0.91 | 108 | Dentistry | Dentistry | 2,022 |
34,820,159 | UBE2E3 regulates cellular senescence and osteogenic differentiation of BMSCs during aging. | PeerJ | PeerJ | 9 | null | 10.7717/peerj.12253 | eng | 2,021 | null | null | 2,021 | 11 | 18 | [BACKGROUND] Osteoporosis has gradually become a public health problem in the world. However, the exact molecular mechanism of osteoporosis still remains unclear. Senescence and osteogenic differentiation inhibition of bone marrow mesenchymal stem cells (BMSCs) are supposed to play an important part in osteoporosis. [M... | Nrf2; Osteogenic differentiation; Osteoporosis; Senescence; UBE2E3 | 0.766 | 124 | Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience | Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience | 2,021 |
34,819,731 | Impact of the Covid-19 Pandemic on Women's Health in Brazil. | Journal of multidisciplinary healthcare | J Multidiscip Healthc | 14 | null | 10.2147/JMDH.S322100 | eng | 2,021 | null | null | 2,021 | 11 | 18 | [PURPOSE] The aim is to verify the impact of the Covid-19 pandemic on women's healthcare and medical assistance in Brazil. [PATIENTS AND METHODS] This exploratory cross-sectional study evaluated a non-probabilistic sample of women above 20 years old, carried out between August and September of 2020, through a snowball ... | Sars-Cov-2 infection; health impact assessment; pandemic | 0.626 | 60 | Nursing; Medicine | Medicine; Nursing | 2,021 |
34,819,388 | 2021 DORIS definition of remission in SLE: final recommendations from an international task force. | Lupus science & medicine | Lupus Sci Med | 8 | 1 | 10.1136/lupus-2021-000538 | eng | 2,021 | 11 | null | null | null | null | [OBJECTIVE] To achieve consensus on a definition of remission in SLE (DORIS). [BACKGROUND] Remission is the stated goal for both patient and caregiver, but consensus on a definition of remission has been lacking. Previously, an international task force consisting of patient representatives and medical specialists publi... | healthcare; lupus erythematosus; outcome assessment; systemic; therapeutics | null | null | null | null | null |
34,819,306 | Sensitivity of modern multislice CT for subarachnoid haemorrhage at incremental timepoints after headache onset: a 10-year analysis. | Emergency medicine journal : EMJ | Emerg Med J | 39 | 11 | 10.1136/emermed-2020-211068 | eng | 2,022 | 11 | null | 2,021 | 11 | 24 | [BACKGROUND] CT performed within 6 hours of headache onset is highly sensitive for the detection of subarachnoid haemorrhage (SAH). Beyond this time frame, if the CT is negative for blood, a lumbar puncture is often performed. Technology improvements in image noise reduction, resolution and motion artefact have enhance... | emergency department; headache | 0.922 | 100 | Critical Care and Intensive Care Medicine; Emergency Medicine; Medicine | Medicine | 2,022 |
34,819,020 | Urinary peptidomics reveals proteases involved in idiopathic membranous nephropathy. | BMC genomics | BMC Genomics | 22 | 1 | 10.1186/s12864-021-08155-3 | eng | 2,021 | 11 | 24 | 2,021 | 11 | 24 | [BACKGROUND] Idiopathic membranous nephropathy (IMN) is a cause of nephrotic syndrome that is increasing in incidence but has unclear pathogenesis. Urinary peptidomics is a promising technology for elucidating molecular mechanisms underlying diseases. Dysregulation of the proteolytic system is implicated in various dis... | Idiopathic membranous nephropathy; Proteases; Urinary peptidomics | 1.258 | 208 | Biotechnology; Genetics | Biochemistry, Genetics and Molecular Biology | 2,021 |
34,818,615 | Development and validation of a nomogram prediction model for malignant transformation of oral potentially malignant disorders. | Oral oncology | Oral Oncol | 123 | null | 10.1016/j.oraloncology.2021.105619 | eng | 2,021 | 12 | null | 2,021 | 11 | 21 | [OBJECTIVE] Oral potentially malignant disorders have increased the risk of oral squamous cell carcinoma. This study developed a nomogram model to assess the risks of malignant transformation of oral potentially malignant disorders. [MATERIALS AND METHODS] A retrospective analysis of patients diagnosed with oral potent... | Dysplasia; Nomogram prediction model; Oral leukoplakia; Oral lichen planus; Oral potentially malignant disorders; Oral squamous cell carcinoma | 1.421 | 143 | Cancer Research; Oncology; Oral Surgery | Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine | 2,021 |
34,818,369 | The impact of changing cigarette smoking habits and smoke-free legislation on orofacial cleft incidence in the United Kingdom: Evidence from two time-series studies. | PloS one | PLoS One | 16 | 11 | 10.1371/journal.pone.0259820 | eng | 2,021 | null | null | 2,021 | 11 | 24 | [BACKGROUND] Both active and passive cigarette smoking have previously been associated with orofacial cleft aetiology. We aimed to analyse the impact of declining active smoking prevalence and the implementation of smoke-free legislation on the incidence of children born with a cleft lip and/or palate within the United... | null | 0.852 | 467 | Multidisciplinary | Multidisciplinary | 2,021 |
34,818,219 | Should Targeted Therapy Be Continued in BRAF-Mutant Melanoma Patients after Complete Remission? | Dermatology (Basel, Switzerland) | Dermatology | 238 | 3 | 10.1159/000518718 | eng | 2,022 | null | null | 2,021 | 10 | 27 | [BACKGROUND] Targeted therapy is used to treat patients with a BRAF-mutated metastatic melanoma and is continued until disease progression or severe toxicity. No robust data on the management of patients achieving a complete remission (CR) are available. [MAIN OBJECTIVE] To determine the relapse rate in the first year ... | Complete remission; Discontinuation; Melanoma-targeted therapy; Relapse | 0.989 | 110 | Dermatology | Medicine | 2,022 |
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