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34,825,397
Combinatorial model of amyloid β and tau reveals synergy between amyloid deposits and tangle formation.
Neuropathology and applied neurobiology
Neuropathol Appl Neurobiol
48
2
10.1111/nan.12779
eng
2,022
2
null
2,021
12
10
[AIMS] To illuminate the pathological synergy between Aβ and tau leading to emergence of neurofibrillary tangles (NFT) in Alzheimer's disease (AD), here, we have performed a comparative neuropathological study utilising three distinctive variants of human tau (WT tau, P301L mutant tau and S320F mutant tau). Previously,...
Alzheimer's disease; gliosis; neurofibrillary tangle; neuroinflammation; pathological synergy; plaque burden
1.785
111
Histology; Neurology; Neurology; Pathology and Forensic Medicine; Physiology
Medicine; Neuroscience
2,022
34,825,064
Retrieval of intrarenal coiled and ruptured guidewire by retrograde intrarenal surgery: A case report and literature review.
Open medicine (Warsaw, Poland)
Open Med (Wars)
16
1
10.1515/med-2021-0385
eng
2,021
null
null
2,021
11
12
[BACKGROUND] Foreign bodies in the kidney have rarely been reported. However, they can be a clinical problem for urologists. We report on a patient with a residual segment of guidewire coating embedded in the renal parenchyma following computed tomography (CT)-guided percutaneous nephrostomy drainage (PCND), and our su...
intrarenal foreign body; percutaneous nephrostomy drainage; retrograde intrarenal surgery
0.214
36
Medicine
Medicine
2,021
34,824,616
Baseline cardiovascular comorbidities, and the influence on cancer treatment decision-making in women with breast cancer.
Ecancermedicalscience
Ecancermedicalscience
15
null
10.3332/ecancer.2021.1293
eng
2,021
null
null
2,021
9
21
[PURPOSE] To measure the baseline prevalence of cardiovascular disease (CVD), its modifiable and non-modifiable risk factors in breast cancer patients, and determine their association with adjuvant treatment decision-making. [METHOD] From 2016 to 2017, 2,127 women newly-diagnosed with breast cancer were prospectively r...
breast cancer; cardiotoxicity; cardiovascular risk factors
0.665
51
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,824,557
Value, Support, and Advancement: An Organization's Role in Faculty Career Intentions in Academic Medicine.
Journal of healthcare leadership
J Healthc Leadersh
13
null
10.2147/JHL.S334838
eng
2,021
null
null
2,021
11
19
[PURPOSE] Faculty engagement in academic medical centers is essential to advancing efficient healthcare delivery, research productivity, and organizational quality. The authors used turnover theory to empirically examine factors that influence faculty engagement, including both aspirational and attrition-related career...
academic medicine; career development; faculty retention; organizational support; turnover theory
null
null
null
null
null
34,824,517
Novel Treatment Approach of Oral Submucous Fibrosis in a 6-year-old Girl: A Case Report.
International journal of clinical pediatric dentistry
Int J Clin Pediatr Dent
14
4
10.5005/jp-journals-10005-1999
eng
2,021
null
null
null
null
null
[BACKGROUND] Oral submucous fibrosis is characterized by stiffness of oral mucosa, blanching and functional limitation, and areca nut predisposition is considered to be one of the main etiological factors. In recent years, there is an increasing prevalence of OSMF in the Indian subcontinent owing to increased consumpti...
Areca nut; Oral Fibrosis; Oral submucous fibrosis; Pediatric
0.162
18
Orthodontics; Pediatrics, Perinatology and Child Health; Oral Surgery; Periodontics
Dentistry; Medicine
2,021
34,824,508
Soothing Effect of an Edible Teether: A Pilot Study in Children during Primary Dentition Age.
International journal of clinical pediatric dentistry
Int J Clin Pediatr Dent
14
4
10.5005/jp-journals-10005-2002
eng
2,021
null
null
null
null
null
[BACKGROUND] Irritability and discomfort are common symptoms during teething periods in infants and toddlers. Non-pharmacological remedies to relieve teething symptoms include teethers and food for chewing. However, the efficacy of such remedies for their soothing effect has been poorly investigated. [MATERIALS AND MET...
Children; Edible teether; Soothing; Teething
0.162
18
Orthodontics; Pediatrics, Perinatology and Child Health; Oral Surgery; Periodontics
Dentistry; Medicine
2,021
34,888,900
Ultrasound Strain Elastography and Contrast-Enhanced Ultrasound in Predicting the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer: A Nomogram Integrating Ki-67 and Ultrasound Features.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
J Ultrasound Med
41
9
10.1002/jum.15900
eng
2,022
9
null
2,021
12
10
[OBJECTIVES] To explore whether conventional elastography and contrast-enhanced ultrasound (CEUS) combined with histopathology can monitor the efficacy of neoadjuvant chemotherapy (NAC) for breast cancer (BC), and develop a Nomogram prediction model monitoring response to NAC. [METHODS] From February 2010 to November 2...
breast cancer; neoadjuvant chemotherapy; nomograms; pathological complete response; ultrasound
0.616
108
Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine
2,022
34,888,754
Real-time virtual intraoperative CT in endoscopic sinus surgery.
International journal of computer assisted radiology and surgery
Int J Comput Assist Radiol Surg
17
2
10.1007/s11548-021-02536-5
eng
2,022
2
null
2,021
12
9
[PURPOSE] Endoscopic sinus surgery (ESS) is typically guided under preoperative computed tomography (CT), which increasingly diverges from actual patient anatomy as the surgery progresses. Studies have reported that the revision surgery rate in ESS ranges between 28 and 47%. This paper presents a method that can update...
Endoscopic surgery; Real-time surgical modification detection; Sinus surgery; Virtual intraoperative CT
0.831
71
Computer Graphics and Computer-Aided Design; Computer Vision and Pattern Recognition; Radiology, Nuclear Medicine and Imaging; Surgery; Biomedical Engineering; Computer Science Applications; Health Informatics; Medicine
Computer Science; Engineering; Medicine
2,022
34,888,498
Pregnant during the COVID-19 pandemic: Knowledge, concerns, attitudes and practices of Pakistani women.
European journal of midwifery
Eur J Midwifery
5
null
10.18332/ejm/142818
eng
2,021
null
null
2,021
11
25
[INTRODUCTION] Data regarding pregnancy and related outcomes with COVID-19 are inconsistent, which leads to difficulties in counselling pregnant women. This brings uncertainty to pregnant women regarding mode of birth, transmission and issues that may occur in case they contract the disease. We conducted this study to ...
COVID-19; Pakistan; attitudes; knowledge; practices; pregnancy
null
13
Maternity and Midwifery; Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine; Nursing
2,021
34,888,182
Comparison of indirect immunofluorescence and western blot method in the diagnosis of hantavirus infections.
World journal of methodology
World J Methodol
11
6
10.5662/wjm.v11.i6.294
eng
2,021
11
20
2,021
11
20
[BACKGROUND] Serologic cross-reactivity between hantaviruses often complicates the interpretation of the results. [AIM] To analyze the diagnostic value of indirect immunofluorescence assay (IFA) and western blot (WB) in the diagnosis of hantavirus infections. [METHODS] One hundred eighty-eight serum samples from Puumal...
Cross-reactivity; Hantaviruses; Indirect immunofluorescence; Serology; Western blot
null
null
null
null
null
34,888,017
Role of hepatitis A virus in diabetes mellitus.
World journal of diabetes
World J Diabetes
12
11
10.4239/wjd.v12.i11.1928
eng
2,021
11
15
null
null
null
[BACKGROUND] Although much information is available regarding hepatitis C virus infection and diabetes, less is known about the relationship between hepatitis A virus (HAV) infection and diabetes. [AIM] To examine the roles of HAV in diabetes risk. [METHODS] This cross-sectional study population included data from the ...
Diabetes mellitus; Glucose metabolism; Immunization; Liver; Vaccination; Viral hepatitis
null
null
null
null
null
34,887,664
MTA1 Expression Can Stratify the Risk of Patients with Multifocal Non-Small Cell Lung Cancers ≤3 cm.
Therapeutics and clinical risk management
Ther Clin Risk Manag
17
null
10.2147/TCRM.S331317
eng
2,021
null
null
2,021
12
3
[PURPOSE] Currently, there is no uniform standard to guide postoperative adjuvant chemotherapy for patients with multifocal non-small cell lung cancers (NSCLCs) ≤3 cm. Therefore, there is an urgent need to explore prognostic molecular markers to identify high-risk patients with multifocal NSCLCs ≤3 cm. We aimed to expl...
MTA1; intrapulmonary metastases; multifocal; multiple primary lung cancers; non-small cell lung cancer; risk of postoperative recurrence
0.598
74
Pharmacology, Toxicology and Pharmaceutics; Safety Research; Chemical Health and Safety; Medicine; Pharmacology
Chemical Engineering; Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
2,021
34,887,136
Avascular Necrosis of the Scaphoid-Preiser Disease: Outcomes of 39 Surgical Cases.
The Journal of hand surgery
J Hand Surg Am
48
3
10.1016/j.jhsa.2021.10.023
eng
2,023
3
null
2,021
12
6
[PURPOSE] There is no established treatment standard for patients with idiopathic avascular necrosis of the scaphoid, also known as Preiser Disease. We evaluated outcomes of operative interventions performed for patients diagnosed with Preiser Disease and assessed scaphoid morphology in the contralateral wrists. [METHO...
Avascular necrosis scaphoid; Preiser disease; scaphoid vascularity; vascularized bone graft
0.983
142
Orthopedics and Sports Medicine; Surgery
Medicine
2,023
34,887,024
Relationships among stress, resilience, and incivility in undergraduate nursing students and faculty during the COVID-19 pandemic: Policy implications for nurse leaders.
Journal of professional nursing : official journal of the American Association of Colleges of Nursing
J Prof Nurs
37
6
10.1016/j.profnurs.2021.08.011
eng
2,021
null
null
2,021
8
28
[BACKGROUND] Developing successful targeted interventions to reduce incivility for undergraduate nursing students and educators will require understanding the differences in their unique experiences. Although resilience may act as protective buffer against stressors, little is known about the relationships between stre...
Incivility; Policy development; Resilience; Stress; Undergraduate nursing education
0.685
67
Nursing; Medicine
Medicine; Nursing
2,021
34,886,879
The ENmix DNA methylation analysis pipeline for Illumina BeadChip and comparisons with seven other preprocessing pipelines.
Clinical epigenetics
Clin Epigenetics
13
1
10.1186/s13148-021-01207-1
eng
2,021
12
9
2,021
12
9
[BACKGROUND] Illumina DNA methylation arrays are high-throughput platforms for cost-effective genome-wide profiling of individual CpGs. Experimental and technical factors introduce appreciable measurement variation, some of which can be mitigated by careful "preprocessing" of raw data. [METHODS] Here we describe the EN...
DNA methylation; Illumina BeadChip; Pipeline; Preprocessing
1.742
86
Developmental Biology; Genetics; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,886,826
Three-dimensional changes in the upper airway and craniomaxillofacial morphology of patients with Angle Class III malocclusion treated with a Frankel III appliance.
BMC oral health
BMC Oral Health
21
1
10.1186/s12903-021-02013-0
eng
2,021
12
9
2,021
12
9
[BACKGROUND] Angle Class III malocclusion, characterized by a concave profile, can cause serious harm to children's physical and mental health. The Frankel III appliance is an effective treatment for Angle Class III malocclusion in mixed denition. We explored three-dimensional changes in the upper airway and craniomaxi...
Craniomaxillofacial morphology; Frankel III appliance; Upper airway
0.79
80
Dentistry
Dentistry
2,021
34,886,134
Placement of Posterior Composite Restorations: A Cross-Sectional Study of Dental Practitioners in Al-Kharj, Saudi Arabia.
International journal of environmental research and public health
Int J Environ Res Public Health
18
23
10.3390/ijerph182312408
eng
2,021
11
25
2,021
11
25
[UNLABELLED] Dental practitioner-related factors can affect the quality of composite restorations. This study aimed to investigate the clinical techniques used by dental practitioners (DPs) while placing direct posterior composite restorations. [METHODS] A questionnaire survey that sought information related to the pla...
composite; dental practitioners; posterior restoration
0.814
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,021
34,886,026
The Relationship between Mindful Attention Awareness, Perceived Stress and Subjective Wellbeing.
International journal of environmental research and public health
Int J Environ Res Public Health
18
23
10.3390/ijerph182312290
eng
2,021
11
23
2,021
11
23
[UNLABELLED] It has been suggested that mindfulness is a predictive factor in self-reported perceived stress. The present study aimed to investigate the link between mindful attention awareness, perceived stress and subjective wellbeing without the presence of a complementary intervention to promote mindfulness-based s...
health; mindfulness; perceived stress; pre-service; teacher stress; teacher wellbeing
0.814
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,021
34,885,997
A Qualitative Study of the Mistreatment of Medical Students by Their Lecturers in Polish Medical Schools.
International journal of environmental research and public health
Int J Environ Res Public Health
18
23
10.3390/ijerph182312271
eng
2,021
11
23
2,021
11
23
[OBJECTIVE] To describe experiences of mistreatment among Polish medical students. [METHODS] Nine focus groups were carried out with 92 students from three medical universities in Poland (in Gdansk, Krakow, and Warsaw). [RESULTS] The mistreatment of medical students included verbal abuse, disregard, and obstacles to pa...
Poland; abuse; medical students; mistreatment
0.814
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,021
34,885,198
Rituximab and Bendamustine (BR) Compared with Rituximab, Bendamustine, and Cytarabine (R-BAC) in Previously Untreated Elderly Patients with Mantle Cell Lymphoma.
Cancers
Cancers (Basel)
13
23
10.3390/cancers13236089
eng
2,021
12
3
2,021
12
3
[BACKGROUND] Rituximab plus bendamustine (BR), and rituximab, bendamustine, and cytarabine (R-BAC) are well-known induction therapies in elderly patients with mantle cell lymphoma (MCL), according to clinical guidelines. However, a direct comparison between the two regimens has never been performed. [METHODS] In this m...
R-BAC; bendamustine; elderly; mantle cell lymphoma; therapy
1.349
157
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,885,101
Correlation between High PD-L1 and EMT/Invasive Genes Expression and Reduced Recurrence-Free Survival in Blood-Circulating Tumor Cells from Patients with Non-Muscle-Invasive Bladder Cancer.
Cancers
Cancers (Basel)
13
23
10.3390/cancers13235989
eng
2,021
11
28
2,021
11
28
[BACKGROUND] PD-L1 represents a crucial immune checkpoint molecule in the tumor microenvironment, identified as a key target for cancer immunotherapy. A correlation between PD-L1 and EMT-related genes expression in various human cancers has been suggested. [METHODS] By ScreenCell filtration, digital droplet PCR and con...
CTC; EMT; NMIBC; PD-L1; RFS; TIMP2; TWIST1; immunotherapy
1.349
157
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,884,314
Spirituality in a Doctor's Practice: What Are the Issues?
Journal of clinical medicine
J Clin Med
10
23
10.3390/jcm10235612
eng
2,021
11
29
2,021
11
29
[INTRODUCTION] It is becoming increasingly important to address the spiritual dimension in the integral care of the people in order to adequately assist them in the processes of their illness and healing. Considering the spiritual dimension has an ethical basis because it attends to the values and spiritual needs of th...
comprehensive care; doctors; health professionals; holistic; physician; religiosity; spiritual care; spirituality
1.04
132
Medicine
Medicine
2,021
34,884,199
Prognostic Role of Subcutaneous and Visceral Adiposity in Hospitalized Octogenarians with COVID-19.
Journal of clinical medicine
J Clin Med
10
23
10.3390/jcm10235500
eng
2,021
11
24
2,021
11
24
[BACKGROUND] We investigated the prognostic significance of visceral and subcutaneous adiposity in octogenarians with COVID-19. [METHODS] This paper presents a monocentric retrospective study that was conducted in acute geriatric wards with 64 hospitalized patients aged 80+ who had a diagnosis of COVID-19 and who under...
COVID-19; chest CT; mortality; subcutaneous fat; visceral fat
1.04
132
Medicine
Medicine
2,021
34,884,198
Risk Factors Associated with Refractory Epilepsy in Patients with Tuberous Sclerosis Complex: A Systematic Review.
Journal of clinical medicine
J Clin Med
10
23
10.3390/jcm10235495
eng
2,021
11
24
2,021
11
24
[BACKGROUND] Epilepsy affects 70-90% of patients with tuberous sclerosis complex (TSC). In one-third of them, the seizures become refractory to treatment. Drug-resistant epilepsy (DRE) carries a significant educational, social, cognitive, and economic burden. Therefore, determining risk factors that increase the odds o...
drug resistant epilepsy; refractory seizures; risk factors; tuberous sclerosis complex
1.04
132
Medicine
Medicine
2,021
34,884,124
Isolating In-Situ Grip and Push Force Distribution from Hand-Handle Contact Pressure with an Industrial Electric Nutrunner.
Sensors (Basel, Switzerland)
Sensors (Basel)
21
23
10.3390/s21238120
eng
2,021
12
4
2,021
12
4
[OBJECTIVES] Grip force during hand tool operation is the primary contributor to tendon strain and related wrist injuries, whereas push force is a contributor to shoulder injuries. However, both cannot be directly measured using a single measurement instrument. The objective of this research was to develop and test an ...
electric nutrunner; grip force; injury prevention; optimization; pistol-grip hand tool; pressure map; push force
0.803
273
Analytical Chemistry; Instrumentation; Atomic and Molecular Physics, and Optics; Biochemistry; Electrical and Electronic Engineering; Information Systems; Medicine
Biochemistry, Genetics and Molecular Biology; Chemistry; Computer Science; Engineering; Medicine; Physics and Astronomy
2,021
34,883,422
Executive functions as a mediator of childhood maltreatment on adult psychopathology: A longitudinal mediation analysis comparing maltreatment factor models.
Child abuse & neglect
Child Abuse Negl
123
null
10.1016/j.chiabu.2021.105369
eng
2,022
1
null
2,021
12
6
[BACKGROUND] Childhood maltreatment (CM), executive functions (EFs), and psychiatric disorders all correlate highly. Changes in EFs during adolescence related to CM present a possible mediating mechanism for the development of psychiatric disorders, yet no study has analyzed this longitudinally while comparing predicti...
Bayesian structural equation model; Childhood maltreatment; Executive functions; Internalizing disorders; Mediation
null
null
null
null
null
34,883,358
Shannon entropy: A novel parameter for quantifying pentagon copying performance in non-demented Parkinson's disease patients.
Parkinsonism & related disorders
Parkinsonism Relat Disord
94
null
10.1016/j.parkreldis.2021.11.037
eng
2,022
1
null
2,021
12
4
[INTRODUCTION] Impaired copy of intersecting pentagons from the Mini-Mental State Examination (MMSE), has been used to assess dementia in Parkinson's disease (PD). We used a digitizing tablet during the pentagon copying test (PCT) as a potential tool for evaluating early cognitive deficits in PD without major cognitive...
In-air movement; Kinematic analysis; Parkinson's disease; Pentagon copying test; Shannon entropy
null
null
null
null
null
34,883,086
Oxidative stress and hepcidin expression in pediatric sickle cell anemia with iron overload.
Hematology/oncology and stem cell therapy
Hematol Oncol Stem Cell Ther
16
3
10.1016/j.hemonc.2021.11.003
eng
2,023
4
4
2,023
4
4
[BACKGROUND] Blood transfusion (BT) is essential in treating sickle cell disease (SCD); however, it leads to iron overload (IO) and oxidative stress. We studied the relationship between oxidative stress, iron status parameters, hepcidin mRNA gene expression, and IO in SCD patients. [METHODS] We classified all SCD patie...
null
null
null
null
null
null
34,882,803
Growth hormone treatment does not to lead to insulin resistance nor excessive rise in IGF-1 levels, while improving height in patients small for gestational age A long-term observational study.
Clinical endocrinology
Clin Endocrinol (Oxf)
96
4
10.1111/cen.14626
eng
2,022
4
null
2,021
12
9
[OBJECTIVE] In children born small for gestational age (SGA), the relationship between growth hormone (GH) treatment and insulin resistance (IR) has only been investigated for a short period, necessitating a longer observation period. This study aimed to evaluate the long-term (10 years) effect of GH to SGA-children on...
efficacy; growth hormone; homeostatic model assessment; insulin resistance; long-term follow-up; safety; small for gestational age
0.854
169
Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,882,771
Underascertainment of COVID-19 cases among first responders: a seroepidemiological study.
Occupational medicine (Oxford, England)
Occup Med (Lond)
72
3
10.1093/occmed/kqab164
eng
2,022
4
19
null
null
null
[BACKGROUND] Providing frontline support places first responders at a high risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. [AIMS] This study was aimed to determine the anti-SARS-CoV-2 seroprevalence in a cohort of first responders (i.e. firefighters/paramedics), to detect the underascer...
COVID-19; SARS-CoV-2; firefighters; infection risk; occupational medicine; paramedics; seroprevalence
0.817
107
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,022
34,882,572
An Evaluation of the Text Illness Monitoring (TIM) Platform for COVID-19: Cross-sectional Online Survey of Public Health Users.
JMIR public health and surveillance
JMIR Public Health Surveill
8
2
10.2196/32680
eng
2,022
2
7
2,022
2
7
[BACKGROUND] The US public health response to the COVID-19 pandemic has required contact tracing and symptom monitoring at an unprecedented scale. The US Centers for Disease Control and Prevention and several partners created the Text Illness Monitoring (TIM) platform in 2015 to assist US public health jurisdictions wi...
COVID-19; SMS text system; contact tracing; symptom monitoring
1.547
64
Health Informatics; Public Health, Environmental and Occupational Health
Medicine
2,022
34,882,115
Low Prevalence of Fragrance Contact Allergy Among Turkish Population: A 24-Year, Cross-Sectional, Tertiary Single-Center, Retrospective Study.
Dermatitis : contact, atopic, occupational, drug
Dermatitis
33
5
10.1097/DER.0000000000000822
eng
null
null
null
2,021
12
9
[BACKGROUND] Limited data exist on fragrance contact allergy among Turkish population. [OBJECTIVE] The aim of this study was to investigate the frequency and characteristics of fragrance contact allergy in Turkey. [METHODS] A retrospective cohort study was conducted on 2566 patients consecutively patch tested with the ...
null
null
null
null
null
null
34,881,530
Cnestis ferruginea Vahl ex DC (Connaraceae) downregulates expression of immediate early genes in kainic acid-induced temporal lobe epilepsy in mice.
Drug metabolism and personalized therapy
Drug Metab Pers Ther
37
2
10.1515/dmpt-2021-0145
eng
2,021
12
9
2,021
12
9
[OBJECTIVES] This study investigates the influence of Cnestis ferruginea (CF) on kainic acid (KA)-induced immediate early genes (IEGs) associated with hippocampal sclerosis in temporal lobe epilepsy (TLE) in mice. [METHODS] Animals were randomly divided into preventive treatment; vehicle (10 mL/kg, p.o.) or CF (400 mg/...
Cnestis ferruginea; brain-derived neurotrophic factors; hippocampus; immediate early genes; kainic acid; temporal lobe epilepsy
null
null
null
null
null
34,880,578
A prospective study on epidemiology of dacryocystitis at a tertiary eye care center in Northern India.
Oman journal of ophthalmology
Oman J Ophthalmol
14
3
10.4103/ojo.ojo_80_21
eng
2,021
null
null
2,021
10
20
[AIM] The aim of this study is to study the prevalence, incidence, and the epidemiological characteristics of the patients of acquired dacryocystitis at a tertiary eye care center of Northern India. [MATERIALS AND METHODS] It was a prospective, cross-sectional study carried out over a period of 2 years (July 2016-July ...
Dacryocystitis; Northern India; epidemiology
0.265
24
Ophthalmology
Medicine
2,021
34,880,158
Comprehensive Pain Control Strategy in Minimally Invasive Mitral Valve Repair.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
Ann Thorac Cardiovasc Surg
28
3
10.5761/atcs.oa.21-00131
eng
2,022
6
20
2,021
12
7
[PURPOSE] The effect of our comprehensive strategy to reduce pain after minimally invasive mitral valve repair through a right mini-thoracotomy was assessed retrospectively. [METHODS] Our comprehensive strategy constituted the following: planned rib cutting to avoid rib injury, sufficient intercostal muscle division to...
minimally invasive cardiac surgery; mitral valve repair; pain control
0.441
49
Surgery; Cardiology and Cardiovascular Medicine; Gastroenterology; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022
34,880,117
Multicenter study evaluating factors associated with treatment outcome for low back pain injections.
Regional anesthesia and pain medicine
Reg Anesth Pain Med
47
2
10.1136/rapm-2021-103247
eng
2,022
2
null
2,021
12
8
[BACKGROUND] There has been a worldwide surge in interventional procedures for low back pain (LBP), with studies yielding mixed results. These data support the need for identifying outcome predictors based on unique characteristics in a pragmatic setting. [METHODS] We prospectively evaluated the association between ove...
back pain; chronic pain; injections; pain management; spinal
1.302
130
Anesthesiology and Pain Medicine; Medicine
Medicine
2,022
34,879,799
Emerging Trends in Abuse-Deterrent Formulations: Technological Insights and Regulatory Considerations.
Current drug delivery
Curr Drug Deliv
19
8
10.2174/1567201818666211208101035
eng
2,022
null
null
null
null
null
[BACKGROUND] Opioid medications are an integral part of the management of acute and chronic severe pain. However, non-medical practice of these prescription drug products is emerging as a serious public health problem. To control this opioid epidemic, USFDA is encouraging pharmaceutical companies to develop Abuse Deter...
Abuse deterrent formulations; Regulatory considerations; controlled release; multipill abuse; opioid; pain management
null
null
null
null
null
34,879,320
Is the pandemic leading to a crisis of trust? Insights from an Italian nationwide study.
Public health
Public Health
202
null
10.1016/j.puhe.2021.10.015
eng
2,022
1
null
2,021
12
5
[OBJECTIVES] Along with mistrust toward politics and journalism, the pandemic is amplifying mistrust in healthcare. To explore trust in key professionals among the Italian population, we focused on perceived change in trust during the pandemic. [STUDY DESIGN] Nationwide online cross-sectional survey (called COCOS). [ME...
COVID-19; Pandemic fatigue; Trust
1.231
102
Medicine; Public Health, Environmental and Occupational Health
Medicine
2,022
34,879,247
A Systematic Review Into the Radiologic Features Predicting Local Recurrence After Stereotactic Ablative Body Radiotherapy (SABR) in Patients With Non-Small Cell Lung Cancer (NSCLC).
International journal of radiation oncology, biology, physics
Int J Radiat Oncol Biol Phys
113
1
10.1016/j.ijrobp.2021.11.027
eng
2,022
5
1
2,021
12
5
[PURPOSE] Posttreatment surveillance for local recurrence (LR) after stereotactic ablative body radiotherapy (SABR) can include both fluorodeoxyglucose-positron emission tomography (FDG-PET) and computed tomography (CT). Radiation-induced lung injury shares a similar appearance to LR after treatment, making the detecti...
null
2.09
286
Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy
2,022
34,878,994
Information Patients With Melanoma Spontaneously Report About Health-Related Quality of Life on Web-Based Forums: Case Study.
Journal of medical Internet research
J Med Internet Res
23
12
10.2196/27497
eng
2,021
12
7
2,021
12
7
[BACKGROUND] There is a general agreement on the importance of health-related quality of life (HRQoL). This type of information is becoming increasingly important for the value assessment of health technology assessment agencies in evaluating the benefits of new health technologies, including medicines. However, HRQoL ...
QoL; health care; quality of life; reimbursement decision-making
1.736
214
Health Informatics
Medicine
2,021
34,878,992
Gender-Specific Impact of Self-Monitoring and Social Norm Information on Walking Behavior Among Chinese College Students Assessed Using WeChat: Longitudinal Tracking Study.
Journal of medical Internet research
J Med Internet Res
23
12
10.2196/29167
eng
2,021
12
7
2,021
12
7
[BACKGROUND] Walking is a simple but beneficial form of physical activity (PA). Self-monitoring and providing information about social norms are the 2 most widely used "mobile health (mHealth)" strategies to promote walking behavior. However, previous studies have failed to discriminate the effect of self-monitoring fr...
gender differences; group identity; mHealth; mobile health; self-monitoring; social norm
1.736
214
Health Informatics
Medicine
2,021
34,878,583
Dietary carotenoid intake and osteoporosis: the National Health and Nutrition Examination Survey, 2005-2018.
Archives of osteoporosis
Arch Osteoporos
17
1
10.1007/s11657-021-01047-9
eng
2,021
12
8
2,021
12
8
[UNLABELLED] Higher intake of β-carotene and β-cryptoxanthin were associated with lower risk of osteoporosis. A very high intake of lutein + zeaxanthin was also associated with lower risk of osteoporosis. These results support the beneficial role of carotenoids on bone health. [PURPOSE] To examine the associations of α...
Bone mineral density; Carotenoids; Dual energy x-ray absorptiometry; NHANES; Osteoporosis
0.693
49
Orthopedics and Sports Medicine
Medicine
2,021
34,878,548
Trends in Prevalence of Tobacco Use by Sex and Socioeconomic Status in 22 Sub-Saharan African Countries, 2003-2019.
JAMA network open
JAMA Netw Open
4
12
10.1001/jamanetworkopen.2021.37820
eng
2,021
12
1
2,021
12
1
[IMPORTANCE] Tobacco companies have shifted their marketing and production to sub-Saharan African countries, which are in an early stage of the tobacco epidemic. [OBJECTIVE] To estimate changes in the prevalence of current tobacco use and socioeconomic inequalities among male and female participants from 22 sub-Saharan...
null
4.031
154
Medicine
Medicine
2,021
34,878,414
Development of Reliable and Valid Negative Mood Screening Tools for Orthopaedic Patients with Musculoskeletal Pain.
Clinical orthopaedics and related research
Clin Orthop Relat Res
480
2
10.1097/CORR.0000000000002082
eng
2,022
2
1
null
null
null
[BACKGROUND] Negative mood is an important risk factor for poor clinical outcomes among individuals with musculoskeletal pain. Screening for negative mood can aid in identifying those who may need additional psychological interventions. Limitations of current negative mood screening tools include (1) high response burd...
null
1.186
244
Medicine; Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,022
34,877,915
Evaluating discrete choice experiment willingness to pay [DCE-WTP] analysis and relative social willingness to pay [RS-WTP] analysis in a health technology assessment of a treatment for an ultra-rare childhood disease [CLN2].
Expert review of pharmacoeconomics & outcomes research
Expert Rev Pharmacoecon Outcomes Res
22
4
10.1080/14737167.2022.2014324
eng
2,022
6
null
2,022
2
23
[BACKGROUND] Conventional cost-effectiveness analysis [CEA] using cost per QALY thresholds may counteract other incentives introduced to foster development of treatments for rare and ultra-rare diseases. Therefore, alternative economic evaluation methods were explored, namely Discrete Choice Experiment Willingness to P...
CLN2; Conjoint Analysis; DCE; DCE-WTP; Discrete Choice Experiment; Discrete Choice Experiment Willingness to Pay; RS-WTP; Rare Disease; Relative Social Willingness to Pay; Willingness to Pay
null
null
null
null
null
34,877,288
Clinical observation of pediatric-type follicular lymphomas in adult: Two case reports.
World journal of clinical cases
World J Clin Cases
9
31
10.12998/wjcc.v9.i31.9542
eng
2,021
11
6
null
null
null
[BACKGROUND] Pediatric-type follicular lymphoma (PTFL) is a unique pathological type in the 4[th] edition of hematopoiesis and lymphoid tissue tumor classification revised by World Health Organization. It is unique in clinical practice and seldom seen in adult. PTFL mainly occurs in the head and neck lymph nodes. Most ...
Adult; Case report; Clinical pathology; Diagnosis; Immunophenotype; Pediatric-type follicular lymphoma
0.38
38
Medicine
Medicine
2,021
34,877,281
Associations with pancreatic exocrine insufficiency: An United Kingdom single-centre study.
World journal of clinical cases
World J Clin Cases
9
31
10.12998/wjcc.v9.i31.9469
eng
2,021
11
6
null
null
null
[BACKGROUND] Pancreatic exocrine insufficiency (PEI) is said to be associated with numerous conditions both within and outside the gastrointestinal (GI) system. The majority of research has been concerned with conditions that reduce the volume of functioning pancreatic tissue or prevent adequate drainage to the small b...
Chronic pancreatitis; Exocrine pancreatic insufficiency; Pancreatic elastase; Proton pump inhibitors; Steatorrhoea
0.38
38
Medicine
Medicine
2,021
34,876,938
Acute cerebral venous thrombosis - still an underdiagnosed pathology in emergency computed tomography of the brain.
Polish journal of radiology
Pol J Radiol
86
null
10.5114/pjr.2021.109490
eng
2,021
null
null
2,021
10
8
[PURPOSE] Acute cerebral venous thrombosis (CVT) is a rare condition that can lead to a serious clinical state; thus, prompt diagnosis and treatment are mandatory. Head computed tomography (CT) plays a crucial role in the initial prompt diagnosis in the emergency setting. The aim of the study was to retrospectively ana...
brain CT; cerebral venous thrombosis; pitfalls
null
null
null
null
null
34,876,825
Overexpression of circACTR2 in Gestational Diabetes Mellitus Predicts Intrauterine Death, Fetal Malformation, and Intrauterine Infection.
Diabetes, metabolic syndrome and obesity : targets and therapy
Diabetes Metab Syndr Obes
14
null
10.2147/DMSO.S316043
eng
2,021
null
null
2,021
11
30
[BACKGROUND] CircRNA actin-related protein 2 homolog (circACTR2) has been reported to participate in high glucose-induced disorders, while its role in gestational diabetes mellitus (GDM) is unknown. This study analyzed the expression pattern of circACTR2 in GDM and evaluated its predictive value for GDM and its adverse...
adverse events; circACTR2; gestational diabetes mellitus
0.685
71
Internal Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,021
34,876,219
5-HT3 receptor antagonists decrease the prevalence of postoperative delirium in older patients undergoing orthopedic lower limb surgery.
Perioperative medicine (London, England)
Perioper Med (Lond)
10
1
10.1186/s13741-021-00222-3
eng
2,021
12
8
2,021
12
8
[BACKGROUND] Delirium is an important postoperative complication. Recent research suggested that 5-hydroxytryptamine 3 (5-HT3) receptor antagonists may have clinical effect in the treatment and prevention of delirium. We investigated the association between 5-HT3 receptor antagonists and the occurrence of postoperative...
5-HT3 receptor antagonist; Older patient; Postoperative delirium
null
null
null
null
null
34,876,183
Outcomes of surgically treated infective endocarditis in a Western Australian population.
Journal of cardiothoracic surgery
J Cardiothorac Surg
16
1
10.1186/s13019-021-01727-0
eng
2,021
12
7
2,021
12
7
[BACKGROUND] Infective endocarditis is a disease that carries high morbidity and mortality. The primary endpoint of this study is to assess factors associated with in-hospital mortality in patients undergoing valvular surgery for infective endocarditis. The secondary endpoint of this study is to assess the incidence of...
Cardiac Surgery; Infective endocarditis; Mortality; Outcomes; Valvular heart surgery
0.345
61
Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,021
34,876,176
COVID-19 in renal transplant recipients and general population: a comparative study of clinical, laboratory, and radiological features, severity, and outcome.
Virology journal
Virol J
18
1
10.1186/s12985-021-01713-x
eng
2,021
12
7
2,021
12
7
[INTRODUCTION] Coronavirus disease 2019 (COVID-19), a novel disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to millions of deaths worldwide. Kidney transplant recipients (KTRs) are a fragile population due to their immunosuppressed status. However, there are limited studies avail...
COVID-19; Immunosuppression; Kidney transplantation; Transplant recipients
1.091
104
Infectious Diseases; Virology
Immunology and Microbiology; Medicine
2,021
34,875,829
Socio-demographic Determinants of Low Physical Activity in Peruvian Adults: Results of a Population-based Survey Performed in 2017-2018.
Journal of preventive medicine and public health = Yebang Uihakhoe chi
J Prev Med Public Health
54
6
10.3961/jpmph.21.418
eng
2,021
11
null
2,021
11
7
[OBJECTIVES] The objective of this study was to determine the prevalence of low physical activity (PA) in Peruvian adults and to identify associated factors. [METHODS] An analytical study was performed using data from the 2017-2018 Nutritional Food Surveillance by Life Stages survey. The outcome variable was low PA (ye...
Peru; Physical activity; Population surveillance; Public health surveillance
null
null
null
null
null
34,875,686
Factors Associated with Adolescents' Support for Product Information and Health Messaging on Alcohol Packaging: A Cross-Sectional Study in the United Kingdom.
Alcohol and alcoholism (Oxford, Oxfordshire)
Alcohol Alcohol
57
3
10.1093/alcalc/agab080
eng
2,022
5
10
null
null
null
[AIMS] Adolescents in the UK are among the heaviest drinkers in Europe. The World Health Organization recommends alcohol product labelling to inform consumers about product information and health risks associated with alcohol use. This study investigates support for product information and health messaging on alcohol p...
null
0.779
111
Medicine; Psychiatry and Mental Health; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
34,875,345
Bifidobacterium breve CCFM1025 attenuates major depression disorder via regulating gut microbiome and tryptophan metabolism: A randomized clinical trial.
Brain, behavior, and immunity
Brain Behav Immun
100
null
10.1016/j.bbi.2021.11.023
eng
2,022
2
null
2,021
12
4
[OBJECTIVE] Psychobiotics, as a novel class of probiotics mainly acting on the gut-brain axis, have shown promising prospects in treating psychiatric disorders. Bifidobacterium breve CCFM1025 was validated to have an antidepressant-like effect in mice. This study aims to assess its psychotropic potential in managing ma...
null
3.033
207
Behavioral Neuroscience; Endocrine and Autonomic Systems; Immunology
Immunology and Microbiology; Neuroscience
2,022
34,875,088
Exploring American Parents' Lived Experiences During the COVID-19 Pandemic: Ramifications for Well-Being.
Journal of pediatric psychology
J Pediatr Psychol
47
2
10.1093/jpepsy/jsab120
eng
2,022
2
14
null
null
null
[OBJECTIVE] The objective of this study was to document the direct impact of the COVID-19 pandemic on parents and families in the United States. [METHODS] Parents' experiences during the pandemic were examined using an online survey (N = 564) collected during May and June 2020. [RESULTS] Parents reported experiencing a...
COVID-19 pandemic; anxiety; depression; parents
1.123
143
Developmental and Educational Psychology; Pediatrics, Perinatology and Child Health
Medicine; Psychology
2,022
34,874,985
Performance of creatinine-based equations for estimating glomerular filtration rate compared to endogenous creatinine clearance.
Jornal brasileiro de nefrologia
J Bras Nefrol
44
2
10.1590/2175-8239-JBN-2021-0109
eng
2,022
null
null
null
null
null
[INTRODUCTION] The guidelines recommend estimating the glomerular filtration rate using serum creatinine-based equations as a predictor of kidney disease, preferably adjusted for local population groups. [METHODS] Cross-sectional study that evaluated the performance of four equations used for estimating GFR compared to...
null
null
null
null
null
null
34,874,951
Ergonomic assessment of work-related musculoskeletal disorder and its determinants among commercial mini bus drivers and driver assistants (mini bus conductors) in Nigeria.
PloS one
PLoS One
16
12
10.1371/journal.pone.0260211
eng
2,021
null
null
2,021
12
7
[INTRODUCTION] Work-related musculoskeletal disorder (WMSD) is a leading causes of occupational injury and disability among drivers and workers in the transport industry. This study evaluated the ergonomically assessed WMSD and its determinants among Nigerian commercial mini bus drivers (BD) and mini bus conductors (BC...
null
0.852
467
Multidisciplinary
Multidisciplinary
2,021
34,874,581
Comparison of the medical burden of COVID-19 with seasonal influenza and measles outbreaks.
Acta paediatrica (Oslo, Norway : 1992)
Acta Paediatr
111
3
10.1111/apa.16210
eng
2,022
3
null
2,021
12
20
[AIM] To examine and compare the medical burden of measles, influenza and COVID-19 outbreaks in the city of Bnei Brak, Israel. [METHODS] The study was conducted during 2018-2021. The numbers of hospitalisations for these infections and their complications were recorded. Hospitalisation rates were determined by using th...
COVID-19; hospitalisations; influenza virus
null
null
null
null
null
34,874,482
Laparoscopic repair of femoral hernia involving the bladder with coexisting indirect inguinal hernia in a young man: a case report.
Surgical case reports
Surg Case Rep
7
1
10.1186/s40792-021-01334-0
eng
2,021
12
7
2,021
12
7
[BACKGROUND] Bladder hernias are rare conditions that are difficult to diagnose preoperatively; many cases are diagnosed intraoperatively or postoperatively due to bladder injury. Most bladder hernias are direct inguinal hernias that involve the bladder in obese men older than 50 years old. We describe a rare case of a...
Femoral hernia; Hernia involving the bladder; Transabdominal preperitoneal repair
null
null
null
null
null
34,873,074
Serum apolipoprotein A1 rather than apolipoprotein B is associated with hypertension prevalence in Chinese people with coronary artery disease.
Blood pressure monitoring
Blood Press Monit
27
2
10.1097/MBP.0000000000000576
eng
2,022
4
1
null
null
null
[OBJECTIVE] Studies on the association of apolipoprotein A1 (ApoA1) and apolipoprotein B (ApoB) with hypertension (HTN) prevalence in patients with coronary artery disease (CAD) are limited. This cross-sectional study aimed to investigate this association in Chinese people in Wuhan, China. [METHODS] Serum ApoA1 and Apo...
null
0.28
67
Advanced and Specialized Nursing; Assessment and Diagnosis; Cardiology and Cardiovascular Medicine; Internal Medicine; Medicine
Medicine; Nursing
2,022
34,872,998
Immigrant status, gender and work disability duration: findings from a linked, retrospective cohort of workers' compensation and immigration data from British Columbia, Canada.
BMJ open
BMJ Open
11
12
10.1136/bmjopen-2021-050829
eng
2,021
12
6
2,021
12
6
[OBJECTIVES] To compare differences in work disability durations of immigrant men and women injured at work to comparable Canadian-born injured workers in British Columbia, Canada. [METHODS] Data on accepted workers compensation claims and immigration status from 1995 and 2012 were used to compare the number of work di...
epidemiology; occupational industrial medicine; public health
0.982
176
Medicine
Medicine
2,021
34,872,729
Most children experience resolution of idiopathic pediatric rectal prolapse with bowel management alone.
Journal of pediatric surgery
J Pediatr Surg
57
10
10.1016/j.jpedsurg.2021.11.003
eng
2,022
10
null
2,021
11
25
[BACKGROUND] Recent studies in children with idiopathic rectal prolapse report up to 48% require surgical intervention to manage refractory disease. We sought to examine outcomes of our non-surgical approach to managing rectal prolapse using a bowel management program. [METHODS] A retrospective review was performed for...
Bowel management; Constipation; Rectal prolapse
0.873
147
Medicine; Pediatrics, Perinatology and Child Health; Surgery
Medicine
2,022
34,872,578
Mutational and clinical spectrum of Japanese patients with hereditary hemorrhagic telangiectasia.
BMC medical genomics
BMC Med Genomics
14
1
10.1186/s12920-021-01139-y
eng
2,021
12
6
2,021
12
6
[BACKGROUND] Hereditary hemorrhagic telangiectasia (HHT) is a dominantly inherited vascular disorder characterized by recurrent epistaxis, skin/mucocutaneous telangiectasia, and organ/visceral arteriovenous malformations (AVM). HHT is mostly caused by mutations either in the ENG or ACVRL1 genes, and there are regional ...
ACVRL1; ENG; Hereditary hemorrhagic telangiectasia
0.955
99
Genetics; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,872,577
Identification and validation of cellular senescence patterns to predict clinical outcomes and immunotherapeutic responses in lung adenocarcinoma.
Cancer cell international
Cancer Cell Int
21
1
10.1186/s12935-021-02358-0
eng
2,021
12
6
2,021
12
6
[BACKGROUND] Aging and senescence can alter immune cell fitness and influence the efficacy of lung cancer treatments, especially immunotherapy. However, the correlations between cellular senescence and tumor microenvironment are still not clearly clarified and the value of cellular senescence-related genes in evaluatin...
Cellular senescence; Immunotherapy; Lung adenocarcinoma; Prognosis; Tumor microenvironment
1.099
90
Cancer Research; Genetics; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,872,299
Predicting infected pancreatic necrosis based on influential factors among the most common types of acute pancreatitis: a retrospective cohort study.
Annals of palliative medicine
Ann Palliat Med
10
11
10.21037/apm-21-2933
eng
2,021
11
null
null
null
null
[BACKGROUND] Biliary and hypertriglyceridemic acute pancreatitis (BAP and HTGAP) are two of the leading etiologies in China. Infected pancreatic necrosis (IPN) is a particular and noticeable condition in the late stage of these diseases; however, the influential correlated factors on IPN and how to predict IPN are uncl...
Acute pancreatitis (AP); etiology; gallstone; hyperglyceridemia; infected pancreatic necrosis (IPN)
null
null
null
null
null
34,872,285
Analysis of immune-related genes in idiopathic pulmonary fibrosis based on bioinformatics and experimental verification.
Annals of palliative medicine
Ann Palliat Med
10
11
10.21037/apm-21-2676
eng
2,021
11
null
null
null
null
[BACKGROUND] Idiopathic pulmonary fibrosis (IPF) is a lung disease involving chronic progressive fibrosis, with unclear pathogenesis. In recent years, people have paid increasing attention to the role of immune mechanism. In this study, bioinformatics analysis was used to determine the potential immune-related biomarke...
CIBERSORT; Idiopathic pulmonary fibrosis (IPF); diagnosis; immune cells
null
null
null
null
null
34,871,381
Long-term impacts of coal mine fire-emitted PM2.5 on hospitalisation: a longitudinal analysis of the Hazelwood Health Study.
International journal of epidemiology
Int J Epidemiol
51
1
10.1093/ije/dyab249
eng
2,022
2
18
null
null
null
[BACKGROUND] Little is known about the long-term health impacts of exposures to landscape fire smoke. We aimed to evaluate the association between exposure to coal mine fire-related particulate matter 2.5 μm or less in diameter (PM2.5) and hospitalisation in the 5 years following the 6-week Hazelwood coal mine fire in ...
Coal mine fire smoke; Hazelwood Health Study; data linkage cohort; fine particulate matter; hospital admission; longitudinal study
2.815
256
Epidemiology; Medicine
Medicine
2,022
34,871,380
Statin use and risk of dementia or Alzheimer's disease: a systematic review and meta-analysis of observational studies.
European journal of preventive cardiology
Eur J Prev Cardiol
29
5
10.1093/eurjpc/zwab208
eng
2,022
5
5
null
null
null
[AIMS] As the potential impact of statins on cognitive decline and dementia is still debated, we conducted a meta-analysis of observational studies to examine the effect of statin use on the risk of Alzheimer's disease (AD) and dementia. [METHODS AND RESULTS] PubMed, Cochrane, and EMBASE were searched since inception t...
Dementia; Meta-analysis; Observational studies; Statins
1.582
130
Cardiology and Cardiovascular Medicine; Epidemiology
Medicine
2,022
34,871,343
Tolerability and SCFA production after resistant starch supplementation in humans: a systematic review of randomized controlled studies.
The American journal of clinical nutrition
Am J Clin Nutr
115
3
10.1093/ajcn/nqab402
eng
2,022
3
4
null
null
null
[BACKGROUND] Resistant starches (RSs) have been advocated as a dietary supplement to address microbiota dysbiosis. They are postulated to act through the production of SCFAs. Their clinical tolerability and effect on SCFA production has not been systematically evaluated. [OBJECTIVES] We conducted a systematic review of...
randomized studies; resistant starch; short-chain fatty acid; systematic review; tolerability
1.96
390
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
34,870,602
A Theory- and Evidence-Based Digital Intervention Tool for Weight Loss Maintenance (NoHoW Toolkit): Systematic Development and Refinement Study.
Journal of medical Internet research
J Med Internet Res
23
12
10.2196/25305
eng
2,021
12
3
2,021
12
3
[BACKGROUND] Many weight loss programs show short-term effectiveness, but subsequent weight loss maintenance is difficult to achieve. Digital technologies offer a promising means of delivering behavior change approaches at low costs and on a wide scale. The Navigating to a Healthy Weight (NoHoW) project, which was fund...
behavior change techniques; emotion regulation; logic models; mHealth; motivation; self-monitoring; self-regulation; user testing; weight management
1.736
214
Health Informatics
Medicine
2,021
34,870,163
Single versus multi-dose intra-articular injection of platelet rich plasma in early stages of osteoarthritis of the knee: A single-blind, randomized, superiority trial.
Archives of rheumatology
Arch Rheumatol
36
3
10.46497/ArchRheumatol.2021.8408
eng
2,021
9
null
2,021
1
14
[OBJECTIVES] This study aims to compare the effectiveness of single, double, and triple doses of intra-articular (IA) platelet rich plasma (PRP) in early stages of osteoarthritis (OA) of the knee. [PATIENTS AND METHODS] This single-blind, randomized, superiority trial included a total of 180 knees of 90 patients (22 ma...
Knee osteoarthritis; orthobiologics; platelet rich plasma
0.302
22
Rheumatology
Medicine
2,021
34,869,075
Characterization of Naturally Acquired Immunity to a Panel of Antigens Expressed in Mature P. falciparum Gametocytes.
Frontiers in cellular and infection microbiology
Front Cell Infect Microbiol
11
null
10.3389/fcimb.2021.774537
eng
2,021
null
null
2,021
11
12
[INTRODUCTION] Naturally acquired immune responses against antigens expressed on the surface of mature gametocytes develop in individuals living in malaria-endemic areas. Evidence suggests that such anti-gametocyte immunity can block the development of the parasite in the mosquito, thus playing a role in interrupting t...
Plasmodium falciparum; malaria transmission; mature gametocytes; naturally acquired immunity; seroepidemiology
1.389
136
Infectious Diseases; Medicine; Microbiology; Microbiology; Immunology
Immunology and Microbiology; Medicine
2,021
34,869,044
The Surgeon's Proficiency Affected Survival Outcomes of Minimally Invasive Surgery for Early-Stage Cervical Cancer: A Retrospective Study of 851 Patients.
Frontiers in oncology
Front Oncol
11
null
10.3389/fonc.2021.787198
eng
2,021
null
null
2,021
11
16
[PURPOSE] To compare the clinical outcomes of patients with early-stage cervical cancer who underwent minimally invasive surgery (MIS) by surgeons in different phases and evaluate whether the proficiency of surgeons affects the survival outcomes. [MATERIALS AND METHODS] A total of 851 patients with early-stage cervical...
early-stage cervical cancer; minimally invasive surgery; open surgery; survival outcomes
1.291
156
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,869,024
Berberine Suppresses Stemness and Tumorigenicity of Colorectal Cancer Stem-Like Cells by Inhibiting m[6]A Methylation.
Frontiers in oncology
Front Oncol
11
null
10.3389/fonc.2021.775418
eng
2,021
null
null
2,021
11
15
[BACKGROUND] Cancer stem cells (CSCs) are able to survive after cancer therapies, resulting in tumor progression and recurrence, as is seen in colorectal cancer. Therapies targeting CSCs are regarded as novel and promising strategies for efficiently eradicating tumors. Berberine, an isoquinoline alkaloid extracted from...
Berberine; FTO; cancer stem-like cells (CSCs); m6A methylation
1.291
156
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,868,957
Assessment of Delivery Quality Assurance for Stereotactic Radiosurgery With Cyberknife.
Frontiers in oncology
Front Oncol
11
null
10.3389/fonc.2021.751922
eng
2,021
null
null
2,021
11
17
[PURPOSE] The purpose of this study is to establish and assess a practical delivery quality assurance method for stereotactic radiosurgery with Cyberknife by analyzing the geometric and dosimetric accuracies obtained using a PTW31016 PinPoint ionization chamber and EBT3 films. Moreover, this study also explores the rel...
Cyberknife; EBT3 film; delivery quality assurance; ionization chamber; small field
1.291
156
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,868,833
COVID-19 Incidence and hospitalization during the delta surge were inversely related to vaccination coverage among the most populous U.S. Counties.
Health policy and technology
Health Policy Technol
11
2
10.1016/j.hlpt.2021.100583
eng
2,022
6
null
2,021
11
30
[OBJECTIVE] We tested whether COVID-19 incidence and hospitalization rates during the Delta surge were inversely related to vaccination coverage among the 112 most populous counties in the United States, comprising 44 percent of the country's total population. [METHODS] We measured vaccination coverage as the percent o...
COVID-19; Delta variant; SARS-CoV-2; Vaccination
1.071
43
Biomedical Engineering; Health Policy
Engineering; Medicine
2,022
34,868,687
Cosmetic Appeal, HRQoL, and Effectiveness of Simple and Pseudotesticular Techniques of Orchidectomy in Prostate Cancer.
Prostate cancer
Prostate Cancer
2021
null
10.1155/2021/9968570
eng
2,021
null
null
2,021
11
26
[INTRODUCTION] Orchidectomy is the most cost-effective means of hormonal therapy for locally advanced or metastatic prostate cancer (LAMP). However, cost-effectiveness should not detract from health-related quality of life (HRQoL) considerations. Bilateral simple orchidectomy (BSO) has been linked to negative psychomet...
null
null
null
null
null
null
34,868,625
Diagnostic value of gadolinium contrast administration for spinal cord magnetic resonance imaging in multiple sclerosis patients and correlative markers of lesion enhancement.
Multiple sclerosis journal - experimental, translational and clinical
Mult Scler J Exp Transl Clin
7
4
10.1177/20552173211047978
eng
2,021
10
null
2,021
11
26
[BACKGROUND] Magnetic resonance imaging is essential for monitoring people with multiple sclerosis, but the diagnostic value of gadolinium contrast administration in spine magnetic resonance imaging is unclear. [OBJECTIVE] To assess the diagnostic value of gadolinium contrast administration in spine magnetic resonance ...
Multiple sclerosis; T2 signal ratio; gadolinium depositions; gadolinium-based contrast agents; spinal magnetic resonance imaging
0.849
34
Neurology; Cellular and Molecular Neuroscience
Medicine; Neuroscience
2,021
34,868,501
Detection of Rotator Cuff Tears by Ultrasound: How Many Scans Do Novices Need to Be Competent?
Clinics in orthopedic surgery
Clin Orthop Surg
13
4
10.4055/cios20259
eng
2,021
12
null
2,021
11
15
[BACKGROUND] Ultrasound is commonly used for evaluating rotator cuff tears. However, little training in ultrasound imaging is provided during orthopedic residents' training period. Therefore, we performed this study to determine how many ultrasound scans are required for orthopedic residents to be competent and self-co...
Diagnosis; Learning curve; Rotator cuff injuries; Shoulder; Ultrasonography
null
null
null
null
null
34,868,340
Evaluating Evidences of Effectiveness in Web-Based Nursing Education Program.
Computational and mathematical methods in medicine
Comput Math Methods Med
2021
null
10.1155/2021/3901916
eng
2,021
null
null
2,021
11
25
[BACKGROUND] Web-based education programs are essential in every field of learning, and in nursing coursework, they can contribute towards behavioral development. It is found that emerging approach of web-based nursing programs is overpowering the traditional education methods and provides flexibility in learning and t...
null
null
null
null
null
null
34,866,920
Talaromyces Marneffei Infection in Lung Cancer Patients with Positive AIGAs: A Rare Case Report.
Infection and drug resistance
Infect Drug Resist
14
null
10.2147/IDR.S340694
eng
2,021
null
null
2,021
11
27
[BACKGROUND] Talaromyces marneffei is considered to commonly cause infection in individuals with human immunodeficiency virus (HIV) infection. However, the epidemiology of T. marneffei has changed, and an increasing number of HIV-negative but immunodeficient patients are infected with T. marneffei. The mechanisms of T....
Talaromyces marneffei; adult immunodeficiency; lung adenocarcinoma
0.944
74
Pharmacology; Pharmacology; Infectious Diseases
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,021
34,866,728
Multicenter validation of Early Warning Scores for detection of clinical deterioration in COVID-19 hospitalized patients.
Medicina intensiva
Med Intensiva
47
1
10.1016/j.medin.2021.11.002
eng
2,023
1
null
2,021
11
30
[OBJECTIVE] Investigate the predictive value of NEWS2, NEWS-C, and COVID-19 Severity Index for predicting intensive care unit (ICU) transfer in the next 24 h. [DESIGN] Retrospective multicenter study. [SETTING] Two third-level hospitals in Argentina. [PATIENTS] All adult patients with confirmed COVID-19, admitted on ge...
COVID-19; Critical care; Early Warning Score; SARS-CoV-2
0.341
41
Critical Care and Intensive Care Medicine
Medicine
2,023
34,866,583
Tp-e/QTc ratio, SYNTAX, and GRACE score in patients who underwent coronary angiography owing to acute coronary syndrome.
Anatolian journal of cardiology
Anatol J Cardiol
25
12
10.5152/AnatolJCardiol.2021.31
eng
2,021
12
null
null
null
null
[OBJECTIVE] Ventricular arrhythmias following acute coronary syndrome (ACS) range from benign to life-threatening fatal arrhythmias. Tpeak-end (Tp-e) interval has been shown to be an important parameter in the assessment of repolarization dispersion. We aimed to evaluate the relationship between SYNTAX and Global Regis...
null
0.354
40
Cardiology and Cardiovascular Medicine
Medicine
2,021
34,866,482
Using advance and emergency care plans during transfer decisions: A grounded theory interview study with care home staff.
Palliative medicine
Palliat Med
36
1
10.1177/02692163211059343
eng
2,022
1
null
2,021
12
6
[BACKGROUND] Advance care planning has been identified as one of few modifiable factors that could reduce hospital transfers from care homes. Several types of documents may be used by patients and clinicians to record these plans. However, little is known about how plans are perceived and used by care home staff at the...
Advance care planning; care homes; nursing homes; patient transfer; qualitative
1.425
128
Anesthesiology and Pain Medicine; Medicine
Medicine
2,022
34,866,434
Relieving from Breathlessness in the Wind: A Meta-Analysis and Subjective Report of Effectiveness of Fan Blowing in Patients with Cardiorespiratory Diseases or Cancer.
The American journal of hospice palliative care
Am J Hosp Palliat Care
39
8
10.1177/10499091211056327
eng
2,022
8
null
2,021
12
4
[OBJECTIVES] Breathlessness is common among terminally ill patients with cardiorespiratory disease or cancer. The experience may induce secondary physiological and behavioral responses that limit patient well-being and independence and cause emotional distress. [METHODS] We conducted a meta-analysis on randomized contr...
breathlessness; cancer; cardiorespiratory; fan blowing; hospice; respiratory rate
null
null
null
null
null
34,866,209
The associations of accommodation and aberrations in myopia control with orthokeratology.
Ophthalmic physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
Ophthalmic Physiol Opt
42
2
10.1111/opo.12930
eng
2,022
3
null
2,021
12
5
[PURPOSE] This study aimed to investigate the effect of orthokeratology (OK) on accommodative function and aberrations, to explore the correlations between them and determine what role they play in myopia control. [METHODS] In this prospective case-controlled study, 61 children were divided into an OK (n = 30) and a si...
aberrations; accommodation; myopia progression; orthokeratology
null
null
null
null
null
34,865,998
An artificial intelligence platform to optimize workflow during ovarian stimulation and IVF: process improvement and outcome-based predictions.
Reproductive biomedicine online
Reprod Biomed Online
44
2
10.1016/j.rbmo.2021.10.006
eng
2,022
2
null
2,021
10
20
[RESEARCH QUESTION] Can workflow during IVF be facilitated by artificial intelligence to limit monitoring during ovarian stimulation to a single day and enable level-loading of retrievals? [DESIGN] The dataset consisted of 1591 autologous cycles in unique patients with complete data including age, FSH, oestradiol and a...
null
0.948
139
Obstetrics and Gynecology; Reproductive Medicine; Developmental Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,865,934
Workplace Violence, Workforce Stability, and Well-being in China's Psychiatric Hospitals.
American journal of preventive medicine
Am J Prev Med
62
4
10.1016/j.amepre.2021.09.013
eng
2,022
4
null
2,021
12
2
[INTRODUCTION] Workplace violence against psychiatric professionals is a growing problem, yet nationally representative data in China are lacking. This study examines workplace violence against psychiatrists and psychiatric nurses in China as well as its association with workforce stability and well-being . [METHODS] D...
null
2.181
260
Epidemiology; Public Health, Environmental and Occupational Health
Medicine
2,022
34,865,209
Predictive Modeling Identifies Total Bleeds at 12-Weeks Postswitch to N8-GP Prophylaxis as a Predictor of Treatment Response.
Thrombosis and haemostasis
Thromb Haemost
122
6
10.1055/s-0041-1739514
eng
2,022
6
null
2,021
12
5
[BACKGROUND] Predicting annualized bleeding rate (ABR) during factor VIII (FVIII) prophylaxis for severe hemophilia A (SHA) is important for long-term outcomes. This study used supervised machine learning-based predictive modeling to identify predictors of long-term ABR during prophylaxis with an extended half-life FVI...
null
1.565
211
Hematology
Medicine
2,022
34,864,978
Fast vs. ultraslow thrombolytic infusion regimens in patients with obstructive mechanical prosthetic valve thrombosis: a pilot randomized clinical trial.
European heart journal. Cardiovascular pharmacotherapy
Eur Heart J Cardiovasc Pharmacother
8
7
10.1093/ehjcvp/pvab083
eng
2,022
9
29
null
null
null
[AIMS] Thrombolysis is an alternative to surgery for mechanical prosthetic valve thrombosis (MPVT). Randomized clinical trials have yet to test the safety and efficacy of a proposed ultraslow thrombolytic infusion regimen. [METHODS AND RESULTS] This single-centre, open-label, pilot randomized clinical trial randomized ...
Cardiac surgery; Mechanical prosthetic valve thrombosis; Prosthetic valve dysfunction; Thrombolysis; Thrombolytic therapy
null
null
null
null
null
34,864,781
Cardiogenic Shock Complicating ST-Segment Elevation Myocardial Infarction: An 18-Year Analysis of Temporal Trends, Epidemiology, Management, and Outcomes.
Shock (Augusta, Ga.)
Shock
57
3
10.1097/SHK.0000000000001895
eng
2,022
3
1
null
null
null
[BACKGROUND] There are limited data on the temporal trends, incidence, and outcomes of ST-segment-elevation myocardial infarction-cardiogenic shock (STEMI-CS). [METHODS] Adult (18 years) STEMI-CS admissions were identified using the National Inpatient Sample (2000-2017) and classified by tertiles of admission year (200...
null
null
null
null
null
null
34,864,672
Association Between Serum Vitamins and the Risk of Alzheimer's Disease in Chinese Population.
Journal of Alzheimer's disease : JAD
J Alzheimers Dis
85
2
10.3233/JAD-215104
eng
2,022
null
null
null
null
null
[BACKGROUND] Alzheimer's disease (AD) is a chronic and fatal neurodegenerative disease; accumulating evidence suggests that vitamin deficiency is associated with the risk of AD. However, studies attempting to elucidate the relationship between vitamins and AD varied widely. [OBJECTIVE] This study aimed to investigate t...
homocysteine; nutrient; vitamin
1.146
188
Clinical Psychology; Geriatrics and Gerontology; Medicine; Psychiatry and Mental Health; Neuroscience
Medicine; Neuroscience; Psychology
2,022
34,864,660
Sex Differences in Behavior and Molecular Pathology in the 5XFAD Model.
Journal of Alzheimer's disease : JAD
J Alzheimers Dis
85
2
10.3233/JAD-210523
eng
2,022
null
null
null
null
null
[BACKGROUND] The prevalence of Alzheimer's disease (AD) is greater in women compared to men, but the reasons for this remain unknown. This sex difference has been widely neglected in experimental studies using transgenic mouse models of AD. [OBJECTIVE] Here, we studied behavior and molecular pathology of 5-month-old 5X...
Activity; ER stress; cognition; female; inflammation; male; social; trophic factors
1.146
188
Clinical Psychology; Geriatrics and Gerontology; Medicine; Psychiatry and Mental Health; Neuroscience
Medicine; Neuroscience; Psychology
2,022
34,864,459
Different combinations of the GLIM criteria for patients awaiting a liver transplant: Poor performance for malnutrition diagnosis but a potentially useful prognostic tool.
Clinical nutrition (Edinburgh, Scotland)
Clin Nutr
41
1
10.1016/j.clnu.2021.11.008
eng
2,022
1
null
2,021
11
14
[BACKGROUND AND AIMS] Studies using the Global Leadership Initiative on Malnutrition (GLIM) criteria for patients with liver cirrhosis are limited. This study aimed to assess the impact of malnutrition according to the GLIM criteria on the outcomes of patients awaiting a liver transplant (LTx) and compare these criteri...
Cirrhosis; GLIM criteria; Liver transplantation; Malnutrition; Mortality
1.658
183
Critical Care and Intensive Care Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
34,864,266
Transarterial endovascular coil embolization in managing intractable bleeding from fibular artery: A case report.
International journal of surgery case reports
Int J Surg Case Rep
89
null
10.1016/j.ijscr.2021.106618
eng
2,021
12
null
2,021
11
23
[INTRODUCTION] Pseudoaneurysms of the fibular artery are rare. Recently, endovascular techniques have been preferred over open surgery. [CASE PRESENTATION] A 50-year-old male patient complained of recurrent bleeding from surgical wounds that had been present for one month. The patient sustained an open cruris fracture....
Coil embolization; Endovascular technique; Fibular artery; Open fracture; Pseudoaneurysm
0.198
31
Surgery
Medicine
2,021
34,864,066
Superior Survival of Fully Cemented Fixation Compared to Hybrid Fixation in a Single Design Rotating Hinge Knee Implant.
The Journal of arthroplasty
J Arthroplasty
37
3
10.1016/j.arth.2021.11.037
eng
2,022
3
null
2,021
12
3
[BACKGROUND] Clinical observations revealed higher rates of aseptic loosening for hybrid fixated rotating hinge knee implants compared to fully cemented ones. We hypothesize that the use of a fully cemented fixation technique had a higher survival rate for aseptic loosening compared to a hybrid fixation technique in a ...
aseptic loosening; fixation; primary total knee arthroplasty; revision total knee arthroplasty; rotating hinge knee implants; survival
2.028
171
Orthopedics and Sports Medicine
Medicine
2,022
34,864,049
The Epidemiology and Burden of Childhood Chronic Pancreatitis in South Australia.
The Journal of pediatrics
J Pediatr
242
null
10.1016/j.jpeds.2021.11.068
eng
2,022
3
null
2,021
12
3
[OBJECTIVE] To assess longitudinal, population-based data on the prevalence and impact of chronic pancreatitis in children. [STUDY DESIGN] Administrative data linkage was used to ascertain an index cohort consisting of all individuals who had an initial diagnosis of chronic pancreatitis before age 19 years in the South...
childhood pancreatitis; chronic pancreatitis; hereditary pancreatitis
1.043
246
Pediatrics, Perinatology and Child Health
Medicine
2,022
34,863,796
Affective explicit and implicit attitudes towards vegetarian and vegan food consumption: The role of mindfulness.
Appetite
Appetite
169
null
10.1016/j.appet.2021.105831
eng
2,022
2
1
2,021
12
1
[OBJECTIVES] It was the main goal of this study to investigate the explicit and implicit affective attitudes towards vegetarian food and the role of mindfulness. The results were related to goal intention in the stage model of self-regulated sustainable behavior change. [METHODS] 182 participants completed a demographi...
Affective attitudes; Compassion; Food rating; Observing; Sustainability; Vegetarianism
1.187
190
Nutrition and Dietetics; Psychology
Nursing; Psychology
2,022
34,863,623
Adults with previous hypospadias surgery during childhood: Beware of bulbar strictures.
Journal of pediatric urology
J Pediatr Urol
18
1
10.1016/j.jpurol.2021.11.001
eng
2,022
2
null
2,021
11
12
[BACKGROUND] Urethral strictures represent the most frequent long-term complication in men after history of hypospadias surgery. [OBJECTIVES] To better define the spectrum of men previously treated for hypospadias during childhood, presenting at an adult urology clinic with persistent urethral complications. [STUDY DES...
Bulbar stricture; Hypospadias; Pediatric urology; Stricture; Transitional urology
0.658
63
Pediatrics, Perinatology and Child Health; Urology
Medicine
2,022