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34,863,175 | YTHDC1-mediated VPS25 regulates cell cycle by targeting JAK-STAT signaling in human glioma cells. | Cancer cell international | Cancer Cell Int | 21 | 1 | 10.1186/s12935-021-02304-0 | eng | 2,021 | 12 | 4 | 2,021 | 12 | 4 | [BACKGROUND] Glioma is a common type of malignant brain tumor with a high mortality and relapse rate. The endosomal sorting complex required for transport (ESCRT) has been reported to be involved in tumorigenesis. However, the molecular mechanisms have not been clarified. [METHODS] Bioinformatics was used to screen the... | Cell cycle; Glioma; VPS25; YTHDC1 | 1.099 | 90 | Cancer Research; Genetics; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
34,863,091 | IL4/IL4R signaling promotes the osteolysis in metastatic bone of CRC through regulating the proliferation of osteoclast precursors. | Molecular medicine (Cambridge, Mass.) | Mol Med | 27 | 1 | 10.1186/s10020-021-00411-2 | eng | 2,021 | 12 | 4 | 2,021 | 12 | 4 | [BACKGROUND] Bone metastasis of colorectal cancer (CRC) often indicates a poor prognosis. Osteolysis can be observed in metastatic sites, implying an aberrant activation of osteoclasts. However, how osteoclastogenesis is regulated in metastatic microenvironment caused by colorectal cancer is still unclear. [METHODS] In... | Bone metastasis; CRC; IL-4/IL-4R; Osteoclast precursors | 1.346 | 136 | Genetics; Genetics; Molecular Medicine; Molecular Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
34,862,904 | Patriarchal Upbringing in the 21[st] Century: The Impact Emotional Abuse Related to Parental Styles Has on the Genesis of Gender Inequality and the Development of Unresolved Trauma in Children. | Psychiatria Danubina | Psychiatr Danub | 33 | Suppl 11 | null | eng | 2,021 | 12 | null | null | null | null | [BACKGROUND] Violence Against Women and Girls (VAWG) (physical, sexual, and psychological/emotional) is a type of structural discrimination that violates the basic human rights of females on a global scale. Cultural norms that glorify male dominance, power imbalances, and abuse of authority are the most encountered rea... | null | null | null | null | null | null |
34,862,633 | Astrogliosis and compensatory neurogenesis after the first ethanol binge drinking-like exposure in the adolescent rat. | Alcoholism, clinical and experimental research | Alcohol Clin Exp Res | 46 | 2 | 10.1111/acer.14757 | eng | 2,022 | 2 | null | 2,021 | 12 | 21 | [BACKGROUND] Multiple ethanol binge drinking-like exposures during adolescence in the rat induce neuroinflammation, loss of neurogenesis, and cognitive deficits in adulthood. Interestingly, the first ethanol binge drinking-like exposure during adolescence also induces short- term impairments in cognition and synaptic p... | adolescence; astrogliosis; binge drinking; hippocampus; neuroinflammation | null | null | null | null | null |
34,862,285 | Positive impact of the COVID-19 pandemic? A longitudinal study on the impact of the COVID-19 pandemic on physicians' work experiences and employability. | BMJ open | BMJ Open | 11 | 12 | 10.1136/bmjopen-2021-050962 | eng | 2,021 | 12 | 3 | 2,021 | 12 | 3 | [OBJECTIVE] The COVID-19 pandemic places an enormous demand on physicians around the world. The aim of this study was to examine the impact of the COVID-19 pandemic on physicians' work experiences and their ability and willingness to continue working in their profession until retirement (ie, their employability). [DESI... | COVID-19; human resource management; mental health | 0.982 | 176 | Medicine | Medicine | 2,021 |
34,862,097 | Preliminary Functional Outcome Following Robotic Intracorporeal Orthotopic Ileal Neobladder Suspension with Round Ligaments in Women with Bladder Cancer. | European urology | Eur Urol | 82 | 3 | 10.1016/j.eururo.2021.11.012 | eng | 2,022 | 9 | null | 2,021 | 11 | 30 | [BACKGROUND] Chronic urinary retention (CUR) is a frequent complication after orthotopic neobladder (ONB) reconstruction in women. To decrease CUR, several open surgical modifications to provide back support to the ONB have been established on the basis of pelvic anatomical differences between females and males. [OBJEC... | Emptying dysfunction; Intracorporeal; Neobladder; Radical cystectomy; Robotic surgery; Round ligaments | 6.963 | 274 | Urology | Medicine | 2,022 |
34,861,855 | The burden and predictors of latent tuberculosis infection among immigrants in South Korea: a retrospective cross-sectional study. | BMC infectious diseases | BMC Infect Dis | 21 | 1 | 10.1186/s12879-021-06922-x | eng | 2,021 | 12 | 3 | 2,021 | 12 | 3 | [BACKGROUND] Approximately one-fourth of the global population is latently infected with Mycobacterium tuberculosis. An understanding of the burden of latent tuberculosis infection (LTBI) among immigrants compared with the general Korean population should be the first step in identifying priority groups for LTBI diagno... | Immigrant screening; Standardized prevalence ratio; Tuberculosis screening | 1.042 | 137 | Infectious Diseases | Medicine | 2,021 |
34,861,851 | Circumstances and toxicology of violence-related deaths among young people who have had contact with the youth justice system: a data linkage study. | BMC public health | BMC Public Health | 21 | 1 | 10.1186/s12889-021-12244-z | eng | 2,021 | 12 | 3 | 2,021 | 12 | 3 | [BACKGROUND] Young people who have had contact with the youth justice system have an increased risk of dying from violence. Examining the context of violence-related deaths is essential in informing prevention strategies. We examined the circumstances and toxicology of violence-related deaths among young people who hav... | Death; Homicide; Medio-legal; Toxicology; Violence; Young people | 1.156 | 211 | Public Health, Environmental and Occupational Health | Medicine | 2,021 |
34,861,821 | Regular feedback on inter-hospital transfer improved the clinical outcome and survival in patients with multiple trauma: a retrospective cohort study. | BMC emergency medicine | BMC Emerg Med | 21 | 1 | 10.1186/s12873-021-00543-y | eng | 2,021 | 12 | 3 | 2,021 | 12 | 3 | [BACKGROUND] Undertriage of major trauma patients is unavoidable, especially in the trauma system of rural areas. Timely stabilization and transfer of critical trauma patients remains a great challenge for hospitals with limited resources. No definitive measure has been proven to improve the outcomes of patients transf... | Feedback; Inter-hospital; Quality; Transfer; Trauma | 0.566 | 51 | Emergency Medicine | Medicine | 2,021 |
34,861,615 | Drowsiness detection using portable wireless EEG. | Computer methods and programs in biomedicine | Comput Methods Programs Biomed | 214 | null | 10.1016/j.cmpb.2021.106535 | eng | 2,022 | 2 | null | 2,021 | 11 | 16 | [BACKGROUND AND OBJECTIVE] The ever-increasing fatality rate due to traffic and workplace accidents, resulting from drowsiness have been a persistent concern during the past years. An efficient technology capable of monitoring and detecting drowsiness can help to alleviate this concern and has potential applications in... | Cross subject validation; Drowsiness detection; Electroencephalogram; Heart rate correlation; Support vector machine | 1.118 | 150 | Computer Science Applications; Health Informatics; Software | Computer Science; Medicine | 2,022 |
34,861,460 | Sarcopenia hinders the decline in disease activity after surgery for people with Crohn's disease: Preliminary results. | Nutrition (Burbank, Los Angeles County, Calif.) | Nutrition | 94 | null | 10.1016/j.nut.2021.111526 | eng | 2,022 | 2 | null | 2,021 | 10 | 24 | [OBJECTIVES] Surgical treatment is an important option for inducing remission in Crohn's disease (CD); indeed, the longer the disease duration, the higher the cumulative surgical rate. Previous studies have shown that the pathogenesis of Crohn's disease is associated with sarcopenia, a condition of reduced skeletal mus... | CDAI; Crohn's disease; IBD; Sarcopenia | 0.966 | 168 | Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism | Medicine; Nursing | 2,022 |
34,861,269 | Gastric deformation models for adaptive radiotherapy: Personalized vs population-based strategy. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology | Radiother Oncol | 166 | null | 10.1016/j.radonc.2021.11.028 | eng | 2,022 | 1 | null | 2,021 | 11 | 30 | [BACKGROUND AND PURPOSE] To create a library of plans (LoP) for gastric cancer adaptive radiotherapy, accurate predictions of shape changes due to filling variations are essential. The ability of two strategies (personalized and population-based) to predict stomach shape based on filling was evaluated for volunteer and... | Adaptive radiotherapy; Deformation model; Gastric cancer; Library of plans; Shape prediction | 1.834 | 189 | Hematology; Oncology; Radiology, Nuclear Medicine and Imaging | Medicine | 2,022 |
34,861,084 | In vitro activities of 8 antifungal agents against geophilic dermatophyte isolates. | Mycoses | Mycoses | 65 | 2 | 10.1111/myc.13408 | eng | 2,022 | 2 | null | 2,021 | 12 | 6 | [BACKGROUND] Members of the Nannizzia gypsea complex are globally the most common geophilic dermatophytes which cause infection in animals and human. Although the susceptibility patterns of anthropophilic or zoophilic dermatophyte species to antifungal agents are well documented, the effectiveness of such drugs against... | Arthroderma; Nannizzia; antifungal susceptibility; efinaconazole; luliconazole | 1.059 | 91 | Dermatology; Medicine; Infectious Diseases | Medicine | 2,022 |
34,861,064 | Upregulation of CD3ζ and L-selectin in antigen-specific cytotoxic T lymphocytes by eliminating myeloid-derived suppressor cells with doxorubicin to improve killing efficacy of neuroblastoma cells in vitro. | Journal of clinical laboratory analysis | J Clin Lab Anal | 36 | 1 | 10.1002/jcla.24158 | eng | 2,022 | 1 | null | 2,021 | 12 | 3 | [BACKGROUND] Agglomeration of myeloid-derived suppressor cells (MDSCs) in tumors impedes immunotherapeutic effects. Doxorubicin (DOX) is currently the most specific drug used for the selective removal of MDSCs. Here, we study the feasibility and mechanism of eliminating MDSCs by DOX to improve antigen-specific cytotoxi... | cytotoxic T lymphocyte; doxorubicin; in vitro; myeloid-derived suppressor cell; neuroblastoma | 0.594 | 67 | Medical Laboratory Technology; Biochemistry; Clinical Biochemistry; Public Health, Environmental and Occupational Health; Hematology; Immunology and Allergy; Microbiology | Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine | 2,022 |
34,861,062 | Altered immune response in organic acidemia. | Pediatrics international : official journal of the Japan Pediatric Society | Pediatr Int | 64 | 1 | 10.1111/ped.15082 | eng | 2,022 | 1 | null | null | null | null | [BACKGROUND] Most patients with organic acidemia suffer from recurrent infections. Although neutropenia has been reported in multiple studies, other components of the immune system have not been evaluated thoroughly. This study was conducted to assess the immune status of patients with organic acidemia (OA). [METHODS] ... | immune deficiency; lymphocyte metabolism; lymphocyte subset; organic acidemia; recent thymic emigrant | 0.364 | 76 | Pediatrics, Perinatology and Child Health | Medicine | 2,022 |
34,860,816 | International Survey on Severe Acute Respiratory Syndrome Coronavirus 2 and Acute Pancreatitis Co-occurrence in Children. | Pancreas | Pancreas | 50 | 9 | 10.1097/MPA.0000000000001923 | eng | 2,021 | 10 | 1 | null | null | null | [OBJECTIVES] It is unknown to what extent coronavirus 2019 (COVID-19) may co-occur with acute pancreatitis (AP) in children and how their clinical course may differ from children with AP alone. [METHODS] An online survey was sent to pediatric gastroenterologists to report on COVID-19 and AP cases from December 11, 2020... | null | 0.804 | 123 | Endocrinology; Endocrinology, Diabetes and Metabolism; Hepatology; Internal Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
34,860,747 | Quantitative Analysis of Radial Peripapillary Capillary Network in Patients With Papilledema Compared with Healthy Subjects Using Optical Coherence Tomography Angiography. | Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society | J Neuroophthalmol | 42 | 1 | 10.1097/WNO.0000000000001460 | eng | 2,022 | 3 | 1 | 2,021 | 10 | 22 | [BACKGROUND] To quantitatively compare the peripapillary microvascular network between patients with papilledema and healthy subjects using swept source optical coherence tomography angiography. [METHODS] In this retrospective observational study, patients with papilledema secondary to idiopathic intracranial hypertens... | null | 0.468 | 74 | Ophthalmology; Medicine; Neurology | Medicine | 2,022 |
34,860,727 | Surveillance-to-Diagnostic Testing Program for Asymptomatic SARS-CoV-2 Infections on a Large, Urban Campus in Fall 2020. | Epidemiology (Cambridge, Mass.) | Epidemiology | 33 | 2 | 10.1097/EDE.0000000000001448 | eng | 2,022 | 3 | 1 | null | null | null | [BACKGROUND] Six months into the COVID-19 pandemic, college campuses faced uncertainty regarding the likely prevalence and spread of disease, necessitating large-scale testing to help guide policy following re-entry. [METHODS] A SARS-CoV-2 testing program combining pooled saliva sample surveillance leading to diagnosis... | null | 1.96 | 203 | Epidemiology | Medicine | 2,022 |
34,860,577 | Novel Insight Into the Association Between Obesity and Hepatocellular Carcinoma Occurrence and Recurrence: High-Throughput Microarray Data Set Analysis of Differentially Expressed Genes. | JCO clinical cancer informatics | JCO Clin Cancer Inform | 5 | null | 10.1200/CCI.21.00094 | eng | 2,021 | 12 | null | null | null | null | [PURPOSE] This study aims to identify potential biomarkers of hepatocellular carcinoma (HCC) occurrence/recurrence and obesity, along with the molecular mechanisms that involve these biomarkers. [METHODS] Three microarray data sets, namely GSE18897, GSE25097, and GSE36376 (genetic suppressor elements associated with ob... | null | 1.669 | 41 | Cancer Research; Health Informatics; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
34,860,558 | Novel Program Offering Remote, Asynchronous Subspecialist Input in Thoracic Oncology: Early Experience and Insights Gained During the COVID-19 Pandemic. | JCO oncology practice | JCO Oncol Pract | 18 | 4 | 10.1200/OP.21.00339 | eng | 2,022 | 4 | null | 2,021 | 12 | 3 | [PURPOSE] AccessHope is a program developed initially by City of Hope to provide remote subspecialist input on cancer care for patients as a supplemental benefit for specific payers or employers. The leading platform for this work has been an asynchronous model of review of medical records followed by a detailed assess... | null | 1.349 | 85 | Health Policy; Oncology; Oncology | Medicine; Nursing | 2,022 |
34,860,465 | Association between fat mass index, fat-free mass index and hemoglobin A1c in a Japanese population: The Tohoku Medical Megabank Community-based Cohort Study. | Journal of diabetes investigation | J Diabetes Investig | 13 | 5 | 10.1111/jdi.13729 | eng | 2,022 | 5 | null | 2,021 | 12 | 28 | [AIMS/INTRODUCTION] Fat mass and fat-free mass affect glycated hemoglobin A1c (HbA1c) levels and blood glucose levels, respectively. The aim of the present study was to examine the association between the fat mass index and fat-free mass index with HbA1c. [MATERIALS AND METHODS] We carried out a cross-sectional study t... | Body composition; Epidemiology; Glycated hemoglobin A1c | 0.992 | 75 | Medicine; Endocrinology, Diabetes and Metabolism; Internal Medicine | Medicine | 2,022 |
34,860,417 | Improving the classification ability of network utilizing fusion technique in contrast-enhanced spectral mammography. | Medical physics | Med Phys | 49 | 2 | 10.1002/mp.15390 | eng | 2,022 | 2 | null | 2,021 | 12 | 15 | [PURPOSE] Contrast-enhanced spectral mammography (CESM) is an effective tool for diagnosing breast cancer with the benefit of its multiple types of images. However, few models simultaneously utilize this feature in deep learning-based breast cancer classification methods. To combine multiple features of CESM and thus a... | contrast-enhanced spectral mammography image; deep learning; generative adversarial network; image classification; image fusion | 1.072 | 218 | Biophysics; Medicine; Radiology, Nuclear Medicine and Imaging | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,860,207 | The Mindful Lawyer: Investigating the Effects of Two Online Mindfulness Programs on Self-Reported Well-Being in the Legal Profession. | Journal of occupational and environmental medicine | J Occup Environ Med | 63 | 12 | 10.1097/JOM.0000000000002393 | eng | 2,021 | 12 | 1 | null | null | null | [OBJECTIVES] Two studies were conducted to determine whether mindfulness meditation could be an effective tool for improving well-being among legal professionals-a population plagued by high rates of depression, anxiety, and stress. [METHODS] Study 1. Legal professionals completed questionnaires before and after an 8-w... | null | 0.732 | 130 | Public Health, Environmental and Occupational Health | Medicine | 2,021 |
34,859,887 | Colonoscopy utilization and outcomes in older adults: Data from the New Hampshire Colonoscopy Registry. | Journal of the American Geriatrics Society | J Am Geriatr Soc | 70 | 3 | 10.1111/jgs.17560 | eng | 2,022 | 3 | null | 2,021 | 12 | 3 | [BACKGROUND] Colonoscopy is frequently performed in older adults, yet data on current use, and clinical outcomes of and follow-up recommendations after colonoscopy in older adults are lacking. [METHODS] This was an observational study using the New Hampshire Colonoscopy Registry of adults age ≥65 years undergoing colon... | age; colorectal cancer screening; polyp surveillance; recommendations | 2.054 | 273 | Geriatrics and Gerontology | Medicine | 2,022 |
34,859,741 | Hyaluronic acid-coated and Olaparib-loaded PEI - PLGA nanoparticles for the targeted therapy of triple negative breast cancer. | Journal of microencapsulation | J Microencapsul | 39 | 1 | 10.1080/02652048.2021.2014586 | eng | 2,022 | 1 | null | 2,021 | 12 | 20 | [AIM] To prepare the hyaluronic acid-coated Olaparib-loaded PEI - PLGA nanoparticles (HA-Ola-PPNPs) and investigate their tumour-targeted anticancer effect. [METHODS] The synthesis of HA-Ola-PPNPs was verified by DLS, TEM and SEM, followed was measured its cytotoxicity using CCK-8 assay. Confocal microscopy was used to... | Olaparib; PEI-PLGA nanoparticles; TNBC; Targeted delivery system; hyaluronic acid | 0.511 | 91 | Colloid and Surface Chemistry; Organic Chemistry; Pharmaceutical Science; Physical and Theoretical Chemistry; Bioengineering | Chemical Engineering; Chemistry; Pharmacology, Toxicology and Pharmaceutics | 2,022 |
34,859,162 | Brace treatment for patients with scoliosis: State of the art. | The South African journal of physiotherapy | S Afr J Physiother | 77 | 2 | 10.4102/sajp.v77i2.1573 | eng | 2,021 | null | null | 2,021 | 10 | 26 | [BACKGROUND] Physiotherapy, brace applications or surgery are the treatment options utilised to manage patients with scoliosis. Many different brace applications are used, and the success rates of orthoses vary. [OBJECTIVES] Brace applications can have detrimental impacts on the patient leading to physical discomfort, ... | brace application; cosmesis; outcomes; rate of success; scoliosis | 0.348 | 13 | Physical Therapy, Sports Therapy and Rehabilitation | Health Professions | 2,021 |
34,858,500 | Key Markers Involved in the Anticolon Cancer Response of CD8+ T Cells through the Regulation of Cholesterol Metabolism. | Journal of oncology | J Oncol | 2021 | null | 10.1155/2021/9398661 | eng | 2,021 | null | null | 2,021 | 11 | 23 | [BACKGROUND] T cell-mediated antitumor immune response is the basis of colorectal cancer (CRC) immunotherapy. Cholesterol plays an important role in T cell signal transduction and function. Apolipoprotein E (APOE) plays a major role in cholesterol metabolism. [OBJECTIVE] To screen and analyze key markers involved in th... | null | null | null | null | null | null |
34,857,924 | Can the long term using of pregabalin in fibromyalgia affect the choroid and retinal nerve fiber layer? | Eye (London, England) | Eye (Lond) | 36 | 12 | 10.1038/s41433-021-01864-9 | eng | 2,022 | 12 | null | 2,021 | 12 | 2 | [BACKGROUND] In this study, the effects of long-term pregabalin use on the choroid and retinal nerve fiber layer were investigated in the fibromyalgia disease. [METHODS] The patient group consisted of 41 fibromyalgia patients using pregabalin. The control group consisted of 41 newly diagnosed fibromyalgia patients who ... | null | null | null | null | null | null |
34,916,262 | Evaluation of a novel CFTR potentiator in COPD ferrets with acquired CFTR dysfunction. | The European respiratory journal | Eur Respir J | 60 | 1 | 10.1183/13993003.01581-2021 | eng | 2,022 | 7 | null | 2,022 | 7 | 13 | [RATIONALE] The majority of chronic obstructive pulmonary disease (COPD) patients have chronic bronchitis, for which specific therapies are unavailable. Acquired cystic fibrosis transmembrane conductance regulator (CFTR) dysfunction is observed in chronic bronchitis, but has not been proven in a controlled animal model... | null | 4.722 | 299 | Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,022 |
34,916,088 | Hemorrhagic shock and encephalopathy syndrome in a patient with a de novo heterozygous variant in KIF1A. | Brain & development | Brain Dev | 44 | 3 | 10.1016/j.braindev.2021.11.007 | eng | 2,022 | 3 | null | 2,021 | 12 | 13 | [INTRODUCTION] KIF1A, a gene that encodes a neuron-specific motor protein, plays important roles in cargo transport along neurites. Variants in KIF1A have been described in three different disorders, and neurodegeneration and spasticity with or without cerebellar atrophy or cortical visual impairment syndrome (NESCAVS)... | Acute encephalopathy (AE); DIC; Motor domain; NESCAV syndrome; PEHO syndrome; Peripheral neuropathy; Spastic paraparesis | null | null | null | null | null |
34,916,034 | Current management and clinical outcomes for patients with haemorrhagic shock due to pelvic fracture in Korean regional trauma centres: A multi-institutional trial. | Injury | Injury | 53 | 2 | 10.1016/j.injury.2021.12.015 | eng | 2,022 | 2 | null | 2,021 | 12 | 8 | [INTRODUCTION] The purpose of this study was to evaluate the current management and clinical outcomes in patients with hemodynamic instability due to pelvic fracture in three regional trauma centres in Korea. [PATIENTS AND METHODS] Three regional trauma centres participated in this study, and 157 patients who were admi... | Haemorrhagic shock; Haemostasis; Pelvic fracture; Trauma centre | 0.698 | 151 | Surgery; Emergency Medicine; Orthopedics and Sports Medicine | Medicine | 2,022 |
34,915,965 | The use of N-terminal (1-76) pro-brain natriuretic peptide in the aetiology of severe respiratory distress in the paediatric emergency department. | Cardiology in the young | Cardiol Young | 32 | 11 | 10.1017/S104795112100490X | eng | 2,022 | 11 | null | 2,021 | 12 | 17 | [INTRODUCTION] Acute respiratory distress is one of the most common reasons for paediatric emergency visits. Paediatric patients require rapid diagnosis and treatment. Our aim in this study was to use N-terminal (1-76) pro-brain natriuretic peptide to differentiate respiratory distress of cardiac and pulmonary origin i... | N-terminal brain natriuretic peptide; emergency department; heart failure; respiratory distress | 0.387 | 68 | Cardiology and Cardiovascular Medicine; Medicine; Pediatrics, Perinatology and Child Health | Medicine | 2,022 |
34,915,935 | Involving and engaging pregnant women in maternity-related research: reflections on an innovative approach. | Research involvement and engagement | Res Involv Engagem | 7 | 1 | 10.1186/s40900-021-00332-8 | eng | 2,021 | 12 | 16 | 2,021 | 12 | 16 | [BACKGROUND] Meaningful public involvement in maternity research remains challenging, partly due to the transient nature of pregnancy. This paper reflects on the development, implementation and simple evaluation of an innovative and inclusive approach to engaging and involving pregnant and early postnatal women in rese... | Ethnic inequality; Exercise in pregnancy; Maternity research; Model of engagement; Patient and public involvement; Pregnancy; Pregnancy yoga; Research engagement | 0.791 | 44 | Health Professions; Health | Health Professions; Social Sciences | 2,021 |
34,915,881 | Blood pressure and risk of cancer: a Mendelian randomization study. | BMC cancer | BMC Cancer | 21 | 1 | 10.1186/s12885-021-09067-x | eng | 2,021 | 12 | 16 | 2,021 | 12 | 16 | [BACKGROUND] Previous large observational cohort studies showed higher blood pressure (BP) positively associated with cancer. We used Mendelian randomization (MR) to obtain less confounded estimates of BP on total and site-specific cancers. [METHODS] We applied replicated genetic instruments for systolic and diastolic ... | Blood pressure; Cancer; Mendelian Randomization | 1.134 | 171 | Cancer Research; Genetics; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
34,915,862 | Mining massive genomic data of two Swiss Braunvieh cattle populations reveals six novel candidate variants that impair reproductive success. | Genetics, selection, evolution : GSE | Genet Sel Evol | 53 | 1 | 10.1186/s12711-021-00686-3 | eng | 2,021 | 12 | 16 | 2,021 | 12 | 16 | [BACKGROUND] This study was carried out on the two Braunvieh populations reared in Switzerland, the dairy Brown Swiss (BS) and the dual-purpose Original Braunvieh (OB). We performed a genome-wide analysis of array data of trios (sire, dam, and offspring) from the routine genomic selection to identify candidate regions ... | null | 1.107 | 91 | Animal Science and Zoology; Ecology, Evolution, Behavior and Systematics; Medicine; Genetics | Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
34,915,085 | Tidal volumes and pressures delivered by the NeoPuff T-piece resuscitator during resuscitation of term newborns. | Resuscitation | Resuscitation | 170 | null | 10.1016/j.resuscitation.2021.12.006 | eng | 2,022 | 1 | null | 2,021 | 12 | 13 | [AIM] T-piece resuscitators are commonly used for respiratory support during newborn resuscitation. This study aimed to describe delivered pressures and tidal volumes when resuscitating term newborns immediately after birth, using the NeoPuff T-piece resuscitator. [METHOD] Observational study from June 2019 through Mar... | NeoPuff; Newborn resuscitation; Positive pressure ventilation; T-piece resuscitator; Tidal volume | 2.242 | 162 | Cardiology and Cardiovascular Medicine; Emergency Medicine; Emergency Nursing | Medicine; Nursing | 2,022 |
34,913,803 | Telemedicine use for pediatric asthma care: a mixed methods study. | The Journal of asthma : official journal of the Association for the Care of Asthma | J Asthma | 59 | 12 | 10.1080/02770903.2021.2019265 | eng | 2,022 | 12 | null | 2,022 | 1 | 3 | [OBJECTIVES] To identify factors associated with telemedicine use for asthma care among children and young adults, and to describe the parent and patient experience of asthma care over telemedicine. [METHODS] Our mixed methods study consisted of an electronic health record analysis and a qualitative focus group analysi... | Telemedicine; asthma; disparities; video visits | 0.554 | 80 | Medicine; Pediatrics, Perinatology and Child Health; Immunology and Allergy; Pulmonary and Respiratory Medicine | Medicine | 2,022 |
34,913,014 | Transcatheter aortic valve replacement for aortic regurgitation in Asians: TAVR for aortic regurgitation in Asians. | AsiaIntervention | AsiaIntervention | 7 | 2 | 10.4244/AIJ-D-21-00007 | eng | 2,021 | 12 | null | null | null | null | [AIMS] Although surgical aortic valve replacement (SAVR) is currently the recommended intervention for patients with native AR without aortic stenosis, a significant proportion of Asian patients undergo transcatheter aortic valve replacement (TAVR), which has not been studied fully for safety and outcomes. This systema... | null | null | null | null | null | null |
34,912,752 | Compliance Issues in Managing 21 Hydroxylase Deficiency and their Short/Long-Term Consequences. | European journal of case reports in internal medicine | Eur J Case Rep Intern Med | 8 | 11 | 10.12890/2021_003048 | eng | 2,021 | null | null | 2,021 | 11 | 30 | [OBJECTIVE] To report a case of untreated classic 21 hydroxylase (OH) deficiency congenital adrenal hyperplasia (CAH) in a transgender patient resulting in pulmonary embolisms (PEs) and bilateral adrenal masses. [METHODS] A 36-year-old male (birth sex: female) presenting with bilateral PEs in the setting of long-standi... | Gender dysphoria; compensated congenital adrenal hyperplasia; pulmonary embolism | null | 19 | Internal Medicine | Medicine | 2,021 |
34,912,400 | Clinical observation of mild hypothermia combined with intravenous thrombolysis in treating patients with acute cerebral infarction. | Pakistan journal of medical sciences | Pak J Med Sci | 37 | 7 | 10.12669/pjms.37.7.4499 | eng | 2,021 | null | null | null | null | null | [OBJECTIVES] To investigate the clinical effect of mild hypothermia combined with intravenous thrombolysis in the treatment of acute cerebral infarction. [METHODS] Eighty-eight patients with acute cerebral infarction in Binzhou People's Hospital between May 2018 and August 2019 were randomly selected and divided into a... | Acute cerebral infarction; Intravenous thrombolysis; Mild hypothermia | null | null | null | null | null |
34,912,076 | Phenome-wide association study (PheWAS) of colorectal cancer risk SNP effects on health outcomes in UK Biobank. | British journal of cancer | Br J Cancer | 126 | 5 | 10.1038/s41416-021-01655-9 | eng | 2,022 | 3 | null | 2,021 | 12 | 15 | [BACKGROUND] Associations between colorectal cancer (CRC) and other health outcomes have been reported, but these may be subject to biases, or due to limitations of observational studies. [METHODS] We set out to determine whether genetic predisposition to CRC is also associated with the risk of other phenotypes. Under ... | null | 2.867 | 281 | Cancer Research; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,911,666 | The reliability of CT numbers as absolute values for diagnostic scanning, dental imaging, and radiation therapy simulation: A narrative review. | Journal of medical imaging and radiation sciences | J Med Imaging Radiat Sci | 53 | 1 | 10.1016/j.jmir.2021.11.007 | eng | 2,022 | 3 | null | 2,021 | 12 | 13 | [BACKGROUND AND PURPOSE] The purpose of this review was to examine the reported factors that affect the reliability of Computed Tomography (CT) numbers and their impact on clinical applications in diagnostic scanning, dental imaging, and radiation therapy dose calculation. [METHODS] A comprehensive search of the litera... | CT number accuracy and uniformity; CT number variability; Patient off-centring; Patient positioning; Size dependence; Tube voltage | 0.286 | 28 | Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging | Health Professions; Medicine | 2,022 |
34,911,607 | Risk factors for preterm birth: a prospective cohort study. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics | Zhongguo Dang Dai Er Ke Za Zhi | 23 | 12 | 10.7499/j.issn.1008-8830.2108015 | eng | 2,021 | 12 | 15 | null | null | null | [OBJECTIVES] To investigate the incidence of preterm birth and risk factors for preterm birth. [METHODS] A prospective cohort study was performed for the pregnant women in early pregnancy and their spouses, who underwent prenatal examination for the first time in Hunan Provincial Maternal and Child Health Care Hospital... | Pregnant woman; Preterm birth; Prospective cohort study; Risk factor | null | null | null | null | null |
34,911,406 | Outcome of one-stage percutaneous endoscopic debridement and lavage combined with percutaneous pedicle screw fixation for lumbar pyogenic spondylodiscitis. | Journal of orthopaedic surgery (Hong Kong) | J Orthop Surg (Hong Kong) | 29 | 3 | 10.1177/23094990211065579 | eng | 2,021 | null | null | null | null | null | [BACKGROUND] This study assessed the therapeutic effect of one-stage percutaneous endoscopic debridement and lavage (PEDL) combined with percutaneous pedicle screw fixation (PPSF) in the treatment of lumbar pyogenic spondylodiscitis. [METHODS] From March 2017 to October 2019, 51 patients diagnosed with pyogenic spondyl... | debridement; minimally invasive surgery; percutaneous pedicle screw fixation; persistent local irrigation; spondylodiscitis | null | null | null | null | null |
34,911,395 | Bioabsorbable dressing impregnated with betamethasone and ciprofloxacin after endoscopic sinus surgery: A randomized, double-blind, placebo-controlled study. | Ear, nose, & throat journal | Ear Nose Throat J | 103 | 7 | 10.1177/01455613211062457 | eng | 2,024 | 7 | null | 2,021 | 12 | 15 | [BACKGROUND] In addition to its hemostatic and stabilization role, biodegradable nasal packing can be used as a carrier for drugs after functional endoscopic sinus surgery (FESS). The aim of this study was to compare the influence of biodegradable synthetic polyurethane foam (NasoPore) soaked with ciprofloxacin, or bet... | dressing; drugs; rhinology; sinusitis; surgery | null | null | null | null | null |
34,911,182 | Relationship between weather parameters and risk of exertional heat injuries during military training. | Singapore medical journal | Singapore Med J | 63 | 12 | 10.11622/smedj.2021183 | eng | 2,022 | 12 | null | 2,021 | 12 | 15 | [INTRODUCTION] The Singapore Armed Forces (SAF) collaborated with the Meteorological Service Singapore (MSS) to study the relationship between weather parameters and the incidents of exertional heat injury (EHI) to mitigate the risk of EHI in a practical manner. [METHODS] Data from the SAF's heat injury registry and MS... | Dew point temperature; exertional heat injury; weather parameters | 0.398 | 74 | Medicine | Medicine | 2,022 |
34,911,147 | Development of novel deep multimodal representation learning-based model for the differentiation of liver tumors on B-mode ultrasound images. | Journal of gastroenterology and hepatology | J Gastroenterol Hepatol | 37 | 4 | 10.1111/jgh.15763 | eng | 2,022 | 4 | null | 2,022 | 1 | 12 | [BACKGROUND AND AIM] Recently, multimodal representation learning for images and other information such as numbers or language has gained much attention. The aim of the current study was to analyze the diagnostic performance of deep multimodal representation model-based integration of tumor image, patient background, a... | B-mode; convolutional neural network; deep multimodal representation learning; liver tumor; machine learning | 1.067 | 156 | Gastroenterology; Hepatology | Medicine | 2,022 |
34,910,987 | Acute Treatment of Isolated Posterior Cerebral Artery Occlusion: Single Center Experience. | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association | J Stroke Cerebrovasc Dis | 31 | 2 | 10.1016/j.jstrokecerebrovasdis.2021.106239 | eng | 2,022 | 2 | null | 2,021 | 12 | 12 | [BACKGROUND AND OBJECTIVES] Randomized trials for mechanical thrombectomy (MT) excluded patients with ischemic strokes due to isolated posterior cerebral artery occlusion (IPCAO), and there is no evidence for best acute treatment strategy in these patients. We aimed to assess the effectiveness and safety of MT in acute... | Acute stroke therapy; Intervention; Intravenous thrombolysis; Ischemic stroke; Mechanical thrombectomy; Posterior cerebral artery; Stroke | 0.713 | 85 | Rehabilitation; Surgery; Cardiology and Cardiovascular Medicine; Neurology | Medicine | 2,022 |
34,910,923 | Hemi-Kock Continent Stoma With Augmentation Cystoplasty: Modifications and Outcomes. | Urology | Urology | 160 | null | 10.1016/j.urology.2021.10.004 | eng | 2,022 | 2 | null | 2,021 | 12 | 12 | [OBJECTIVE] To evaluate the long-term outcomes and impact of surgical modifications on the need for secondary surgery of the Hemi-Kock continent catheterizable stoma, comprising a detubularized ileal segment with an attached stapled ileoileal intussusception of the catheterizable channel, in patients with complex lower... | null | 0.686 | 197 | Urology | Medicine | 2,022 |
34,910,859 | Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico. | The New England journal of medicine | N Engl J Med | 386 | 6 | 10.1056/NEJMoa2116185 | eng | 2,022 | 2 | 10 | 2,021 | 12 | 15 | [BACKGROUND] NVX-CoV2373 is an adjuvanted, recombinant spike protein nanoparticle vaccine that was shown to have clinical efficacy for the prevention of coronavirus disease 2019 (Covid-19) in phase 2b-3 trials in the United Kingdom and South Africa, but its efficacy had not yet been tested in North America. [METHODS] W... | null | 26.015 | 1,231 | Medicine | Medicine | 2,022 |
34,910,833 | LncRNA LOXL1-AS1 inhibits proliferation of PDLSCs and downregulates IL-1β in periodontitis patients. | Journal of periodontal research | J Periodontal Res | 57 | 2 | 10.1111/jre.12962 | eng | 2,022 | 4 | null | 2,021 | 12 | 15 | [BACKGROUND] The carcinogenic role of lncRNA LOXL1-AS1 in thoracic aortic aneurysm has been confirmed, but its role in the pathogenesis of periodontitis remains unclear. Our preliminary deep sequencing data revealed LOXL1-AS1 downregulation in periodontitis and its inverse correlation with IL-1β, a critical inflammator... | LOXL1-AS1; periodontal ligament stem cells; periodontitis; proliferation | 0.816 | 102 | Periodontics | Dentistry | 2,022 |
34,910,437 | Setting up a PCR Laboratory for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). | Clinical laboratory | Clin Lab | 67 | 12 | 10.7754/Clin.Lab.2021.210438 | eng | 2,021 | 12 | 1 | null | null | null | [BACKGROUND] Urgent clinical and public health have the challenge of massive testing for the detection of SARS-CoV-2 to provide the information about individual infection status and patient management. All these efforts are significant for government officials to evaluate the spread of a new disease and trace the conta... | null | null | null | null | null | null |
34,910,390 | Total mesometrial resection (TMMR) for cervical cancer FIGO IB-IIA: first results from the multicentric TMMR register study. | Journal of gynecologic oncology | J Gynecol Oncol | 33 | 1 | 10.3802/jgo.2022.33.e9 | eng | 2,022 | 1 | null | 2,021 | 12 | 6 | [OBJECTIVE] The surgical concept of total mesometrial resection (TMMR) and therapeutic lymphadenectomy (tLNE) for the treatment of early cervical cancer is based on the ontogenetic cancer field model. Unicentric data show excellent locoregional control rates without adjuvant chemoradiation. However, there are so far no... | Cervical Cancer; Lymphadenectomy; Operative Surgical Procedures; Recurrence | 0.922 | 56 | Medicine; Obstetrics and Gynecology; Oncology | Medicine | 2,022 |
34,910,368 | Transmission of SARS-CoV-2 from humans to a 16-year-old domestic cat with comorbidities in Pennsylvania, USA. | Veterinary medicine and science | Vet Med Sci | 8 | 2 | 10.1002/vms3.695 | eng | 2,022 | 3 | null | 2,021 | 12 | 15 | [BACKGROUND AND OBJECTIVES] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), besides causing human infection, has been shown to naturally infect several susceptible animal species including large cats (tigers, lions, pumas, spotted leopards), dogs, cats, ferrets, gorillas and minks. Cats and minks are cont... | SARS-CoV-2; cat; histopathology; infection; lungs; rRT-PCR; transmission | 0.451 | 30 | Veterinary | Veterinary | 2,022 |
34,909,882 | Effect of Lactobacillus species on apoptosis-related genes BCL2, BAX, and caspase 3 in the testes of gamma-irradiated rats. | Revista da Associacao Medica Brasileira (1992) | Rev Assoc Med Bras (1992) | 67 | 11 | 10.1590/1806-9282.20210634 | eng | 2,021 | 11 | null | null | null | null | [OBJECTIVE] Ionizing radiation has various applications, including uses in medicine, industry, agriculture, and research. However, ionizing radiation is accompanied by side effects in normal radiosensitive tissues. Probiotics as natural radioprotective agents can protect normal tissues from ionizing radiation. In this ... | null | 0.334 | 51 | Medicine | Medicine | 2,021 |
34,909,495 | Teachers' knowledge about type 1 diabetes in public female elementary schools in Northern Saudi Arabia. | Journal of preventive medicine and hygiene | J Prev Med Hyg | 62 | 3 | 10.15167/2421-4248/jpmh2021.62.3.2064 | eng | 2,021 | 9 | null | 2,021 | 9 | 15 | [BACKGROUND] Saudi Arabia ranks the 4th country in the world in incidence rate of Type 1 Diabetes (T1D), which is usually diagnosed in children and teens. Managing T1D at school is important for children's short- and long-term health. Little is known about how much teachers are compatible to support students with diabe... | Saudi Arabia; Schools; Students; Teachers; Type 1 diabetes | 0.452 | 40 | Infectious Diseases; Public Health, Environmental and Occupational Health | Medicine | 2,021 |
34,909,479 | Status of radiotherapy staff during the coronavirus disease 2019 (COVID-19) epidemic in China. | Precision radiation oncology | Precis Radiat Oncol | 5 | 4 | 10.1002/pro6.1134 | eng | 2,021 | 12 | null | 2,021 | 11 | 8 | [OBJECTIVE] In December 2019, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) broke out in Wuhan, China. The pandemic has posed a great challenge to radiation oncology departments, as interruptions in radiation therapy (RT) increase the risks of cancer recurren... | anxiety; coronavirus disease 2019; psychological interventions; radiotherapy staff; workload | null | null | null | null | null |
34,909,417 | Push-out bond strength and marginal adaptation of apical plugs with bioactive endodontic cements in simulated immature teeth. | Restorative dentistry endodontics | Restor Dent Endod | 46 | 4 | 10.5395/rde.2021.46.e53 | eng | 2,021 | 11 | null | 2,021 | 10 | 20 | [OBJECTIVES] This study evaluates the bond strength and marginal adaptation of mineral trioxide aggregate (MTA) Repair HP and Biodentine used as apical plugs; MTA was used as reference material for comparison. [MATERIALS AND METHODS] A total of 30 single-rooted teeth with standardized, artificially created open apices ... | Apexification; Calcium Silicate Materials; Marginal Adaptation; Mineral Trioxide Aggregate; Push-out Bond Strength; Scanning Electron Microscopy | null | null | null | null | null |
34,909,015 | Virtual Reality and Psychedelics for the Treatment of Psychiatric Disease: A Systematic Literature Review. | Clinical neuropsychiatry | Clin Neuropsychiatry | 17 | 6 | 10.36131/cnfioritieditore20200606 | eng | 2,020 | 12 | null | null | null | null | [OBJECTIVE] Hallucinogenic substances or psychedelic drugs have been historically used by humans worldwide for centuries, and interest grows around them because of the therapeutic potential that they pose for mental disease. Virtual Reality (VR), has been highly developed and improved in the last decade, and it is also... | hallucinogen; psychedelic; psychiatric disorders; psychiatry; virtual reality | null | null | null | null | null |
34,908,866 | The Contribution of Psychological Distress to Resting Palpitations in Patients Who Recovered from Severe COVID-19. | International journal of general medicine | Int J Gen Med | 14 | null | 10.2147/IJGM.S334715 | eng | 2,021 | null | null | 2,021 | 12 | 6 | [BACKGROUND] Increasing numbers of patients have recovered from severe coronavirus disease 2019 (COVID-19) in Wuhan, China. This study aimed to evaluate the association of psychological distress with resting palpitations in recovered patients. [METHODS] In this prospective cohort study, consecutive patients who recover... | anxiety; coronavirus disease 2019; depression; palpitations; sinus tachycardia | null | null | null | null | null |
34,908,836 | Alterations in Peripheral C-Reactive Protein and Inflammatory Cytokine Levels in Patients with Panic Disorder: A Systematic Review and Meta-Analysis. | Neuropsychiatric disease and treatment | Neuropsychiatr Dis Treat | 17 | null | 10.2147/NDT.S340388 | eng | 2,021 | null | null | 2,021 | 12 | 7 | [BACKGROUND] Accumulating evidence has shown the important role of the inflammatory process in the pathophysiology of mental disorders. However, the relative levels of inflammatory markers in patients with panic disorder (PD) have rarely been evaluated. The aim of the present study was to conduct a systematic review to... | CRP; interleukin; panic disorder | 0.774 | 98 | Psychiatry and Mental Health; Biological Psychiatry | Medicine; Neuroscience | 2,021 |
34,908,516 | Free-field correction values for RadioEar DD65v2 circumaural audiometric headphones. | International journal of audiology | Int J Audiol | 61 | 7 | 10.1080/14992027.2021.1998678 | eng | 2,022 | 7 | null | 2,021 | 12 | 15 | [OBJECTIVE] Free-field correction values were measured for RadioEar DD65v2 audiometric headphones. [DESIGN] Free-field correction values, that is, the difference GF-GC between the free-field sensitivity level GF and the ear simulator sensitivity level GC, were determined by loudness level comparisons between the headph... | Audiometry; RadioEar DD65v2; free-field correction; speech audiometry | 0.971 | 102 | Linguistics and Language; Speech and Hearing | Health Professions; Social Sciences | 2,022 |
34,908,507 | Association between olfactory dysfunction and COVID-19 severity: A prospective study in a highly complex hospital in Peru. | Ear, nose, throat journal | Ear Nose Throat J | 103 | 1_suppl | 10.1177/01455613211066691 | eng | 2,024 | 6 | null | 2,021 | 12 | 15 | [INTRODUCTION] Olfactory dysfunction has been included among the early symptoms of coronavirus disease (COVID-19). Evidence suggests that a relationship exists between the duration of olfaction disorders and the probability of developing severe COVID-19. Given the scope of the COVID-19 pandemic, this study aimed to det... | COVID-19; anosmia; coronavirus; hyposmia; olfactory dysfunction; smell | null | null | null | null | null |
34,908,484 | Management of Type 2 Retinopathy of Prematurity or Less in Infants Aged 45 Weeks Postmenstrual Age or Older. | Ophthalmic surgery, lasers imaging retina | Ophthalmic Surg Lasers Imaging Retina | 52 | 12 | 10.3928/23258160-20211031-02 | eng | 2,021 | 12 | null | 2,021 | 12 | 1 | [BACKGROUND AND OBJECTIVE] This study aimed to identify the degree of concordance between fluorescein angiograms (FA) and fundus photographs (FP) in assessing the severity and potential need for treatment in infants 45 weeks or older postmenstrual age (PMA) with type 2 or less retinopathy of prematurity (ROP). [PATIENT... | null | null | null | null | null | null |
34,908,253 | Glycemic control is associated with lower odds of mortality and successful extubation in severe COVID-19. | Journal of osteopathic medicine | J Osteopath Med | 122 | 2 | 10.1515/jom-2021-0182 | eng | 2,021 | 12 | 16 | 2,021 | 12 | 16 | [CONTEXT] Corticosteroids, specifically dexamethasone, have become the mainstay of treatment for moderate to severe COVID-19. Although the RECOVERY trial did not report adverse effects of corticosteroids, the METCOVID (Methylprednisolone as Adjunctive Therapy for Patients Hospitalized with COVID-19) study reported a hi... | COVID-19; corticosteroids; glycemic control; hyperglycemia | null | 61 | Complementary and Alternative Medicine; Complementary and Manual Therapy | Health Professions; Medicine | 2,021 |
34,907,503 | Consent models in Canadian critical care randomized controlled trials: a scoping review. | Canadian journal of anaesthesia = Journal canadien d'anesthesie | Can J Anaesth | 69 | 4 | 10.1007/s12630-021-02176-y | eng | 2,022 | 4 | null | 2,021 | 12 | 14 | [PURPOSE] Our primary objective was to describe consent models used in Canadian-led adult and pediatric intensive care unit (ICU/PICU) randomized controlled trials (RCTs). Our secondary objectives were to determine the consent rate of ICU/PICU RCTs that did and did not use an alternate consent model to describe consent... | critical care; deferred consent; informed consent; intensive care unit; pediatric intensive care unit | null | null | null | null | null |
34,906,825 | Barbed pharyngoplasty for obstructive sleep apnea: A meta-analysis. | American journal of otolaryngology | Am J Otolaryngol | 43 | 2 | 10.1016/j.amjoto.2021.103306 | eng | 2,022 | null | null | 2,021 | 12 | 3 | [PURPOSE] The purpose of this study was to perform a meta-analysis of barbed pharyngoplasty (BP) in the treatment of obstructive sleep apnea (OSA). [METHODS] Databases included PubMed, Ovid MEDLINE, Cochrane Library, Web of Science and Scopus, and reference lists. Relevant articles were searched through August 2021, fo... | Barbed pharyngoplasty; Meta-analysis; Obstructive sleep apnea; Systematic review | null | null | null | null | null |
34,906,738 | Evaluation of quantitative light-induced fluorescence to assess lesion depth in cavitated and non-cavitated root caries lesions - An in vitro study. | Photodiagnosis and photodynamic therapy | Photodiagnosis Photodyn Ther | 37 | null | 10.1016/j.pdpdt.2021.102675 | eng | 2,022 | 3 | null | 2,021 | 12 | 11 | [BACKGROUND] This in vitro study aimed to assess carious lesions on root surfaces using quantitative light-induced fluorescence (QLF) and to compare the readings with axial lesion depth on µCT. [METHODS] The root surfaces of 107 extracted human teeth were included after visual-tactile inspection. For further analysis, ... | Caries detection; Micro-CT; QLF; Quantitative light-induced fluorescence; Root caries | 0.633 | 73 | Biophysics; Dermatology; Pharmacology; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,906,226 | Recurrent autoimmune hypophysitis treated with rituximab: a case report. | Journal of medical case reports | J Med Case Rep | 15 | 1 | 10.1186/s13256-021-03146-0 | eng | 2,021 | 12 | 15 | 2,021 | 12 | 15 | [BACKGROUND] Autoimmune hypophysitis is a rare condition that often results in enlargement of the pituitary gland and hypopituitarism due to inflammatory infiltration. Management of autoimmune hypophysitis can include long-term hormonal replacement and close control of the inflammatory pituitary mass. Mass-related symp... | Autoimmune hypophysitis; CD20+ B-cells; Immunotherapy; Lymphocytic hypophysitis; Monoclonal antibody; Primary hypophysitis; Rituximab | 0.289 | 43 | Medicine | Medicine | 2,021 |
34,906,191 | Leukocyte telomere length and amyotrophic lateral sclerosis: a Mendelian randomization study. | Orphanet journal of rare diseases | Orphanet J Rare Dis | 16 | 1 | 10.1186/s13023-021-02135-2 | eng | 2,021 | 12 | 14 | 2,021 | 12 | 14 | [BACKGROUND] Observational studies have suggested that telomere length is associated with amyotrophic lateral sclerosis (ALS). However, whether this association is causal remains unclear. In this study, we aimed to explore the causal relationship between leukocyte telomere length (LTL) and ALS by a two-sample Mendelian... | Amyotrophic lateral sclerosis; Leukocyte telomere length; Mendelian randomization; Risk factors | 1.105 | 143 | Medicine; Pharmacology; Genetics | Medicine | 2,021 |
34,906,150 | TRB3 mediates vascular remodeling by activating the MAPK signaling pathway in hypoxic pulmonary hypertension. | Respiratory research | Respir Res | 22 | 1 | 10.1186/s12931-021-01908-4 | eng | 2,021 | 12 | 14 | 2,021 | 12 | 14 | [BACKGROUND] Hypoxic pulmonary hypertension (PH) is a refractory pulmonary vascular remodeling disease, and the efficiency of current PH treatment strategies is unsatisfactory. Tribbles homolog 3 (TRB3), a member of the pseudokinase family, is upregulated in diverse types of cellular stresses and functions as either a ... | Hypoxia; MAPK; PASMCs; PH; TRB3 | 1.813 | 134 | Pulmonary and Respiratory Medicine | Medicine | 2,021 |
34,906,021 | Brain tumors and circulating micrornas: a systematic review and diagnostic meta-analysis. | Expert review of molecular diagnostics | Expert Rev Mol Diagn | 22 | 2 | 10.1080/14737159.2022.2019016 | eng | 2,022 | 2 | null | 2,022 | 1 | 11 | [PURPOSE] Brain tumors (BT) are among the most prevalent cancers in recent years. Various studies have examined the diagnostic role of microRNAs in different diseases; however, their diagnostic role in BT has not been comprehensively investigated. This meta-analysis was performed to assess microRNAs in the blood of pat... | Circulating microRNAs; brain tumors; diagnostic biomarker; glioblastoma; glioma | 0.91 | 92 | Pathology and Forensic Medicine; Genetics; Molecular Biology; Molecular Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,905,748 | Birth weight and the risk of overall breast cancer, premenopausal and postmenopausal breast cancer in adulthood: a dose-response meta-analysis of observational studies. | Menopause (New York, N.Y.) | Menopause | 29 | 1 | 10.1097/GME.0000000000001885 | eng | 2,021 | 12 | 13 | 2,021 | 12 | 13 | [IMPORTANCE] The effect of birth weight on breast cancer across different menopausal states remains unknown. [OBJECTIVE] The aim of this study was to systematically evaluate the association of birth weight with the risk of overall breast cancer (OBC) and premenopausal and postmenopausal breast cancer during adulthood. ... | null | 0.984 | 125 | Obstetrics and Gynecology | Medicine | 2,021 |
34,905,478 | Evaluation of the Online Learning Experience of Dalhousie Dentistry and Dental Hygiene Students during COVID-19 Pandemic Outbreak. | Journal (Canadian Dental Association) | J Can Dent Assoc | 87 | null | null | eng | 2,021 | 11 | null | null | null | null | [PURPOSE/OBJECTIVE] On 11 March 2020, the World Health Organization declared COVID-19 a pandemic, and universities transitioned to online learning. The objective of this study was to evaluate the experience of students with the online education program offered during the initial phase of the pandemic. [METHODS] In Apri... | null | null | null | null | null | null |
34,905,303 | Influence of orthodontic brackets and permanent retainers on the diagnostic image quality of MRI scans: A preliminary study. | Dental and medical problems | Dent Med Probl | 58 | 4 | 10.17219/dmp/132390 | eng | 2,021 | null | null | null | null | null | [BACKGROUND] Orthodontic treatment with fixed mechanotherapy using appliances and permanent retainers bonded after treatment is a routine procedure performed in clinical dentistry. Patients with braces or retainers sometimes need to undergo magnetic resonance imaging (MRI) for various reasons. Radiologists do not know ... | MRI distortion; bonded retainers; magnetic resonance imaging; orthodontic brackets | null | null | null | null | null |
34,904,903 | The effect of pulsatile versus non-pulsatile flow during cardiopulmonary bypass on cerebral oxygenation: A randomized trial. | Asian cardiovascular thoracic annals | Asian Cardiovasc Thorac Ann | 30 | 4 | 10.1177/02184923211045915 | eng | 2,022 | 5 | null | 2,021 | 12 | 14 | [BACKGROUND] The present study aims to compare regional oxygen supply determined by Near-Infrared Spectroscopy in the course of pulsatile perfusion with non-pulsatile perfusion during cardiopulmonary bypass in patients undergoing valvular heart surgery. [METHODS] In this prospective randomized single-blinded trial, we ... | Cardiopulmonary bypass; cardiac surgery; cerebral oxygenation; heart valves; near-infrared spectroscopy; pulsatile flow; randomized clinical trial | null | null | null | null | null |
34,904,695 | A retrospective study evaluating the trend of opioid prescribing in low back pain at a UK teaching hospital. | Journal of opioid management | J Opioid Manag | 17 | 6 | 10.5055/jom.2021.0681 | eng | 2,021 | null | null | null | null | null | [INTRODUCTION] Current data suggest that the chronic use of strong opioids in low back pain (LBP) is increasing. There is evidence for the use of opioids in the initial management of LBP, but the efficacy in the long term is unknown. This article intends to examine the use of opioids in patients with chronic LBP over a... | null | null | null | null | null | null |
34,904,667 | Plasma VP8∗-Binding Antibodies in Rotavirus Infection and Oral Vaccination in Young Bangladeshi Children. | Journal of the Pediatric Infectious Diseases Society | J Pediatric Infect Dis Soc | 11 | 4 | 10.1093/jpids/piab120 | eng | 2,022 | 4 | 30 | null | null | null | [BACKGROUND] Despite the availability and success of live-attenuated oral vaccines, rotavirus (RV) remains the leading cause of pediatric gastroenteritis worldwide. Next-generation vaccines targeting RV VP8∗ are under evaluation, but the role of VP8∗-specific antibodies in human immunity to RV and their potential as im... | correlates of protection; oral vaccines; rotavirus; rotavirus vaccines; viral gastroenteritis | 1.547 | 55 | Infectious Diseases; Medicine; Pediatrics, Perinatology and Child Health | Medicine | 2,022 |
34,904,630 | Protein Kinase CK2 Maintains Reciprocal Balance Between Th17 and Treg Cells in the Pathogenesis of UC. | Inflammatory bowel diseases | Inflamm Bowel Dis | 28 | 6 | 10.1093/ibd/izab312 | eng | 2,022 | 6 | 3 | null | null | null | [BACKGROUND] T helper 17 and regulatory T cells balance have crucial effects on the development of ulcerative colitis (UC). Currently, how to break this balance has not yet been found. Protein kinase CK2 is involved in the pathogenesis of immune-related disorders. However, its effects on the development of UC are obscu... | CD4+ T cell; CK2; SIRT1; UC | 1.834 | 183 | Gastroenterology; Immunology and Allergy | Medicine | 2,022 |
34,904,448 | Association Between MTHFD1 1958G A Variant and non-Syndromic Cleft lip and Palate: An Updated Meta-Analysis. | The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association | Cleft Palate Craniofac J | 59 | 11 | 10.1177/10556656211046486 | eng | 2,022 | 11 | null | 2,021 | 12 | 14 | [INTRODUCTION] Non-syndromic cleft lip and palate (NSCLP) is one of the most common and challenging congenital deformities worldwide. Previous research has linked the methylenetetrahydrofolate dehydrogenase1 (MTHFD1) gene to orofacial cleft (OFC) susceptibility via a complex metabolism. Studies analyzing the MTHFD1 195... | MTHFD1; NSCLP; SNP; meta-analysis; rs2236225 | 0.545 | 96 | Oral Surgery; Otorhinolaryngology | Dentistry; Medicine | 2,022 |
34,903,935 | Risk factors associated with ticks and Rickettsia spp. exposure in wild boars (Sus scrofa), hunting dogs, and hunters of Brazil. | Veterinary world | Vet World | 14 | 10 | 10.14202/vetworld.2021.2745-2749 | eng | 2,021 | 10 | null | 2,021 | 10 | 25 | [BACKGROUND AND AIM] Wild boars have recently been implicated as the maintainers and carriers of Amblyomma spp. ticks, which are essential for Rickettsia spp. transmission. Consequently, wild boar hunting may increase the risk of tick exposure and subsequent human tick-borne infection and disease. Therefore, this study... | Brazilian spotted fever; hunting activities; wild boars | 0.457 | 56 | Veterinary | Veterinary | 2,021 |
34,903,480 | Correlation Between Imaging-Based Intermediate Endpoints and Overall Survival in Men With Metastatic Castration-Resistant Prostate Cancer: Analysis of 28 Randomized Trials Using the Prostate Cancer Clinical Trials Working Group (PCWG2) Criteria in 16,511 Patients. | Clinical genitourinary cancer | Clin Genitourin Cancer | 20 | 1 | 10.1016/j.clgc.2021.11.007 | eng | 2,022 | 2 | null | 2,021 | 11 | 15 | [INTRODUCTION/BACKGROUND] Radiographic progression-free survival (rPFS) based on Prostate Cancer Working Group 2 (PCWG2) has been increasingly used as a meaningful imaging-based intermediate endpoint (IBIE) for overall survival (OS) in patients with metastatic castration-resistant prostate cancer (mCRPC). In randomized... | Castration-resistant prostate cancer; Imaging-based intermediate endpoint; Overall survival; Prostate Cancer Working Group 2; Radiographic progression-free survival | 1.031 | 59 | Urology; Oncology | Medicine | 2,022 |
34,903,446 | Pulmonary embolism - An EFIM guideline critical appraisal and adaptation for practicing clinicians. | European journal of internal medicine | Eur J Intern Med | 96 | null | 10.1016/j.ejim.2021.12.001 | eng | 2,022 | 2 | null | 2,021 | 12 | 11 | [BACKGROUND] Several trials have been conducted in the last decades that challenged the management of patients with acute pulmonary embolism (PE) in terms of diagnosis and treatment. Updated international clinical practice guidelines (CPGs) endorsed the evidence from these trials. The aim of this document was to adapt ... | Adapt; Clinical practice guideline; Consensus; Guidelines; Internal medicine; Pulmonary embolism | 0.995 | 98 | Internal Medicine | Medicine | 2,022 |
34,903,064 | Alteration of autophagy-related protein 5 (ATG5) levels and Atg5 gene expression in diabetes mellitus with and without complications. | Diabetes vascular disease research | Diab Vasc Dis Res | 18 | 6 | 10.1177/14791641211062050 | eng | 2,021 | null | null | null | null | null | [BACKGROUND] Autophagy is a catabolic mechanism that involves lysosomal-dependent degradation of unnecessary intracellular components and responsible for normal cellular homeostasis. Autophagy pathway and its key participant ATG5/LC3 are associated with several pathologies such as diabetes mellitus and its complication... | Atg5 gene; Diabetes Mellitus; LC3B; autophagy; diabetic nephropathy | null | null | null | null | null |
34,903,003 | Comprehensive analysis to identify DNA damage response-related lncRNA pairs as a prognostic and therapeutic biomarker in gastric cancer. | Mathematical biosciences and engineering : MBE | Math Biosci Eng | 19 | 1 | 10.3934/mbe.2022026 | eng | 2,022 | 1 | null | 2,021 | 11 | 18 | [OBJECTIVE] Gastric cancer (GC) is the fifth most common malignancy and the fourth leading cause of cancer-related mortality worldwide. The identification of valuable predictive signatures to improve the prognosis of patients with GC is becoming a realistic prospect. DNA damage response-related long noncoding ribonucle... | DNA damage response; lncRNA pairs; prognosis; therapy; tumor immunity | null | null | null | null | null |
34,902,677 | Selenium concentration is associated with occurrence and diagnosis of three cardiovascular diseases: A systematic review and meta-analysis. | Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) | J Trace Elem Med Biol | 70 | null | 10.1016/j.jtemb.2021.126908 | eng | 2,022 | 3 | null | 2,021 | 12 | 7 | [BACKGROUND] Selenium (Se) is a vital trace element playing its biological functions through selenoprotein, which has been implicated in various physiological and pathological processes. A growing number of studies indicate that low Se increases the risk of cardiovascular diseases (CVDs). This meta-analysis aimed to co... | Coronary heart disease; Heart failure; Meta-analysis; Myocardial infarction; Selenium levels | 0.625 | 98 | Inorganic Chemistry; Biochemistry; Molecular Medicine | Biochemistry, Genetics and Molecular Biology; Chemistry | 2,022 |
34,902,583 | The impact of the COVID-19 preventive measures on influenza transmission: molecular and epidemiological evidence. | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases | Int J Infect Dis | 116 | null | 10.1016/j.ijid.2021.12.323 | eng | 2,022 | 3 | null | 2,021 | 12 | 10 | [OBJECTIVE] We quantify the impact of COVID-19-related control measures on the spread of human influenza virus H1N1 and H3N2. [METHODS] We analyzed case numbers to estimate the end of the 2019-2020 influenza season and compared it with the median of the previous 9 seasons. In addition, we used influenza molecular data ... | COVID-19; case; effective population size; epidemiology; genetic diversity; influenza | 2.006 | 140 | Infectious Diseases; Medicine; Microbiology | Medicine | 2,022 |
34,901,476 | Light flashes during proton and photon radiotherapy: A multicenter prospective observational study. | Technical innovations patient support in radiation oncology | Tech Innov Patient Support Radiat Oncol | 20 | null | 10.1016/j.tipsro.2021.11.003 | eng | 2,021 | 12 | null | 2,021 | 11 | 24 | [BACKGROUND] Patients who receive radiation therapy sometimes complain of a light flash during irradiation. The details of the characteristics of this light have not been described. [PURPOSE] To evaluate light flashes during photon and proton radiotherapy. [METHODS AND MATERIALS] A prospective observational study was p... | Cherenkov; Light flash; Observation study; Prospective; Radiotherapy | null | null | null | null | null |
34,901,294 | Characterizing Head Impact Exposure in Men and Women During Boxing and Mixed Martial Arts. | Orthopaedic journal of sports medicine | Orthop J Sports Med | 9 | 12 | 10.1177/23259671211059815 | eng | 2,021 | 12 | null | 2,021 | 12 | 7 | [BACKGROUND] The accumulation of subconcussive impacts has been implicated in permanent neurological impairment. A gap in understanding the relationship between head impacts and neurological function is the lack of precise characterization and quantification of forces that individuals experience during sports training ... | boxing; head impact; head impact power; mixed martial arts; peak angular acceleration; peak linear acceleration | 1.037 | 68 | Orthopedics and Sports Medicine | Medicine | 2,021 |
34,901,176 | A Retrospective Study on Alopecia Areata in Children: Clinical Characteristics and Treatment Choices. | Skin appendage disorders | Skin Appendage Disord | 7 | 6 | 10.1159/000518042 | eng | 2,021 | 11 | null | 2,021 | 9 | 14 | [BACKGROUND] Although children are affected frequently with alopecia areata (AA), data are limited on clinical characteristics and treatment choices. [MATERIALS AND METHODS] We retrospectively reviewed the records of the pediatric dermatology department over a 12-year period to identify children with AA. Clinical data ... | Alopecia areata; Males; Minoxidil; Ophiasis; Topical steroids | 0.614 | 28 | Dermatology | Medicine | 2,021 |
34,900,561 | Gene Mutation Annotation and Pedigree for Pulmonary Arterial Hypertension Patients in Han Chinese Patients. | Global heart | Glob Heart | 16 | 1 | 10.5334/gh.1002 | eng | 2,021 | null | null | 2,021 | 10 | 18 | [BACKGROUND] The etiology of pulmonary arterial hypertension (PAH) in the Han Chinese population is poorly understood. [OBJECTIVES] The aim of this study was to assess gene variants and associated functional annotations for PAH in Han Chinese patients. [METHODS] This is an ethnicity-based multi-centre study. Blood samp... | ClinVar database; DAVID database; gene annotation; gene mutation; heritable pulmonary arterial hypertension; pulmonary arterial hypertension | 0.8 | 55 | Community and Home Care; Cardiology and Cardiovascular Medicine; Epidemiology | Medicine; Nursing | 2,021 |
34,900,547 | Regional Strain Pattern and Correlation with Cardiac Magnetic Resonance Imaging in Fabry Disease. | Journal of cardiovascular echography | J Cardiovasc Echogr | 31 | 3 | 10.4103/jcecho.jcecho_119_20 | eng | 2,021 | null | null | 2,021 | 10 | 26 | [BACKGROUND] Cardiovascular disease is the most common cause of death among Fabry disease patients, who carry significantly increased risk for heart failure and sudden cardiac death. Echocardiographic strain imaging and cardiac MRI are important clinical tools for early detection of cardiomyopathy before onset of systo... | Cardiac magnetic resonance imaging; echocardiogram; fabry disease; global longitudinal strain; regional strain | 0.221 | 17 | Cardiology and Cardiovascular Medicine; Radiology, Nuclear Medicine and Imaging | Medicine | 2,021 |
34,900,345 | Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice. | Translational neuroscience | Transl Neurosci | 12 | 1 | 10.1515/tnsci-2020-0198 | eng | 2,021 | 1 | 1 | 2,021 | 11 | 30 | [OBJECTIVES] Cryptotanshinone (CPT), a natural quinoid diterpene, isolated from Salvia miltiorrhiza, has shown various pharmacological properties. However, its effect on chronic unpredictable stress (CUS)-induced depression phenotypes and the underlying mechanism remain unclear. Therefore, the aim of this study was to ... | BDNF; cryptotanshinone; depression; microglial polarization; neurogenesis; neuroinflammation | null | null | null | null | null |
34,900,165 | Isolation and characterization of bacteriophages from wastewater sources on Enterococcus spp. isolated from clinical samples. | Iranian journal of microbiology | Iran J Microbiol | 13 | 5 | 10.18502/ijm.v13i5.7434 | eng | 2,021 | 10 | null | null | null | null | [BACKGROUND AND OBJECTIVES] In recent decades, enterococcal resistance to antimicrobials has greatly increased. Furthermore, these chemicals include several side effects on the patients. Since no reports are available of the bacteriophages' effects on eukaryotic cells, they can be good solutions for multidrug-resistant... | Antibiotics; Bacteriophages; Enterococcus; Wastewaters | null | null | null | null | null |
34,900,086 | Serum Galectin-3 as a Potential Predictive Biomarker Is Associated with Poststroke Cognitive Impairment. | Oxidative medicine and cellular longevity | Oxid Med Cell Longev | 2021 | null | 10.1155/2021/5827812 | eng | 2,021 | null | null | 2,021 | 12 | 2 | [OBJECTIVE] Galectin-3, an inflammatory mediator derived from microglia, participates in the pathophysiological process of various neurological diseases. However, the relationship between galectin-3 and poststroke cognitive impairment (PSCI) remains ambiguous. This research purposed to prove whether serum galectin-3 ca... | null | 1.233 | 170 | Biochemistry; Medicine; Aging; Cell Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
34,899,928 | Evaluation of CD30 expression in B ALL and its correlation with MRD(Minimum Residual Disease). | Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences | J Res Med Sci | 26 | null | 10.4103/jrms.JRMS_1024_20 | eng | 2,021 | null | null | 2,021 | 10 | 18 | [BACKGROUND] This study was conducted to evaluate CD30 expression in minimum residual disease after chemotherapy in B-acute lymphoblastic leukemia (B-ALL). [MATERIALS AND METHODS] This was a cross-sectional study on 30 new cases of B-ALL between 2018 and 2019. We checked CD30 expressions in fresh bone marrow aspirates ... | Acute lymphoblastic leukemia; B lymphoblastic leukemia; CD30; flow cytometry; minimum residual disease | 0.427 | 59 | Medicine | Medicine | 2,021 |
34,898,530 | Development and Internal Validation of Machine Learning Algorithms for Predicting Hyponatremia After TJA. | The Journal of bone and joint surgery. American volume | J Bone Joint Surg Am | 104 | 3 | 10.2106/JBJS.21.00718 | eng | 2,022 | 2 | 2 | null | null | null | [BACKGROUND] The development of hyponatremia after total joint arthroplasty (TJA) may lead to several adverse events and is associated with prolonged inpatient length of stay as well as increased hospital costs. The purpose of this study was to develop and internally validate machine learning algorithms for predicting ... | null | null | null | null | null | null |
34,898,312 | Delirium in a Tertiary Pediatric Cardiac Intensive Care Unit: Risk Factors and Outcomes. | Journal of intensive care medicine | J Intensive Care Med | 37 | 10 | 10.1177/08850666211066892 | eng | 2,022 | 10 | null | 2,021 | 12 | 13 | [OBJECTIVE] Delirium is an increasingly recognized hospital complication associated with poorer outcomes in critically ill children. We aimed to evaluate risk factors for screening positive for delirium in children admitted to a pediatric cardiac intensive care unit (CICU) and to examine the association between duratio... | analgesics; benzodiazepines; child; critical care; critical illness; dexmedetomidine; hypnotics and sedatives; length of stay; opioids; retrospective studies | 1.039 | 75 | Critical Care and Intensive Care Medicine | Medicine | 2,022 |
34,898,046 | Analysis of CDK12 alterations in a pan-cancer database. | Cancer medicine | Cancer Med | 11 | 3 | 10.1002/cam4.4483 | eng | 2,022 | 2 | null | 2,021 | 12 | 12 | [BACKGROUND] CDK12 inactivation leading to increased neoantigen burden has been hypothesized to sensitize tumors to immune checkpoint inhibition. Pan-cancer data regarding the frequency of CDK12 alterations are limited. We aimed to characterize CDK12 alterations across all cancer types through real-world clinical-grade... | biomarkers; cancer genetics; clinical cancer research; genomics | 1.188 | 95 | Oncology; Radiology, Nuclear Medicine and Imaging; Cancer Research | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,898,031 | The new therapeutic option for female stress and stress-predominant mixed urinary incontinence: Periurethral hypertonic saline (10%) injection. | Lower urinary tract symptoms | Low Urin Tract Symptoms | 14 | 3 | 10.1111/luts.12422 | eng | 2,022 | 5 | null | 2,021 | 12 | 12 | [OBJECTIVES] We aimed to evaluate the safety and efficacy of periurethral hypertonic saline (10% NaCl) injection in the treatment of stress urinary incontinence (SUI) and stress-predominant mixed urinary incontinence (S-MUI) in women. [METHODS] This was a prospective study conducted between January 2014 and April 2018 ... | female; hypertonic saline solution; injections; stress urinary incontinence; therapy; urinary incontinence | null | null | null | null | null |
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