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34,857,562 | Blood pressure-lowering medicines implemented in 12 African countries: the cross-sectional multination EIGHT study. | BMJ open | BMJ Open | 11 | 12 | 10.1136/bmjopen-2021-049632 | eng | 2,021 | 12 | 2 | 2,021 | 12 | 2 | [OBJECTIVE] In Africa, the number of patients with hypertension is expected to reach 216.8 million by 2030. Large-scale data on antihypertensive medications used in Sub-Saharan Africa (SSA) are scarce.Here, we describe antihypertensive drug strategies and identify treatment factors associated with blood pressure (BP) c... | hypertension; public health; therapeutics | 0.982 | 176 | Medicine | Medicine | 2,021 |
34,857,450 | A Cepstral Peak Prominence (CPP) Voice Analysis in Iranian Post-lingual Deaf Adult Cochlear Implant Users. | Journal of voice : official journal of the Voice Foundation | J Voice | 38 | 3 | 10.1016/j.jvoice.2021.10.021 | eng | 2,024 | 5 | null | 2,021 | 11 | 29 | [OBJECTIVE] In standardized connected speech samples, cepstral peak prominence (CPP) and smoothed CPP (CPPS) have been described as accurate parameters to evaluate voice quality. Lack of normal auditory feedback in post-lingually deaf CI users might influence tuning the acoustic parameters in speech production. Based o... | Acoustic analysis; Cepstral peak prominence CPP-CPPS; Cochlear implant CI-CAPE-V; Hearing loss-postlingual | 0.573 | 114 | LPN and LVN; Otorhinolaryngology; Speech and Hearing | Health Professions; Medicine; Nursing | 2,024 |
34,857,205 | A body shape index could serve to identify individuals with metabolic syndrome and increased arterial stiffness in the middle-aged population. | Clinical nutrition ESPEN | Clin Nutr ESPEN | 46 | null | 10.1016/j.clnesp.2021.10.001 | eng | 2,021 | 12 | null | 2,021 | 10 | 8 | [BACKGROUND] A body shape index (ABSI) is a novel anthropometric measure calculated using waist circumference (WC), body mass index (BMI), and body height. This study investigated the usefulness of ABSI to identify individuals with metabolic syndrome (MetS) and increased arterial stiffness in the middle-aged population... | ABSI; Arterial stiffness; CAVI; Metabolic syndrome; Visceral fat accumulation | 0.617 | 46 | Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism | Medicine; Nursing | 2,021 |
34,856,948 | Hsa_circ_0008434 regulates USP9X expression by sponging miR-6838-5p to promote gastric cancer growth, migration and invasion. | BMC cancer | BMC Cancer | 21 | 1 | 10.1186/s12885-021-09052-4 | eng | 2,021 | 12 | 2 | 2,021 | 12 | 2 | [BACKGROUND] The role of circular RNAs (circRNAs) in the occurrence and development of gastric cancer (GC) has recently attracted increasing interest. The following study investigates the role of a newly discovered hsa_circ_0008434, which has been confirmed to be highly expressed in GC tissues, in regulating GC biologi... | Gastric cancer; Invasion; Migration; Proliferation; hsa_circ_0008434 | 1.134 | 171 | Cancer Research; Genetics; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
34,856,629 | Association of HPV and EBV in Oral Verrucous Squamous Cell Carcinoma and Oral Verrucous Hyperplasia. | European journal of dentistry | Eur J Dent | 16 | 2 | 10.1055/s-0041-1735907 | eng | 2,022 | 5 | null | 2,021 | 12 | 2 | [OBJECTIVE] Oral verrucous squamous cell carcinoma or oral verrucous carcinoma (OVC) is a rare verrucous variant of oral squamous cell carcinoma (OSCC), which accounts for 2 to 12% of all oral carcinomas. Oral verrucous hyperplasia (OVH) is clinically similar to OVC and has been proposed to be a precursor lesion of OVC... | null | 0.654 | 53 | Dentistry | Dentistry | 2,022 |
34,856,557 | Effects of Long Noncoding RNA H19 on Isoflurane-Induced Cognitive Dysregulation by Promoting Neuroinflammation. | Neuroimmunomodulation | Neuroimmunomodulation | 29 | 2 | 10.1159/000519124 | eng | 2,022 | null | null | 2,021 | 12 | 2 | [INTRODUCTION] Isoflurane (ISO) may cause neuronal apoptosis and synaptic disorder during development, and damage long-term learning and memory function. This observation aimed to study the function of H19 in vitro and in vivo tests and the further mechanism was identified. [METHODS] ISO cell models and rat models were... | H19; Isoflurane; Neuroinflammation; Neurotoxicity; miR-17-5p | 0.663 | 76 | Endocrine and Autonomic Systems; Endocrinology; Immunology; Neurology | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Neuroscience | 2,022 |
34,856,042 | Novel insights into pivotal risk factors for rectal carriage of extended-spectrum-β-lactamase-producing enterobacterales within the general population in Lower Saxony, Germany. | Journal of applied microbiology | J Appl Microbiol | 132 | 4 | 10.1111/jam.15399 | eng | 2,022 | 4 | null | 2,021 | 12 | 13 | [AIMS] To estimate the prevalence of extended-spectrum-β-lactamase (ESBL)-producing enterobacterales (ESBL-E) carriage in the general population of Lower Saxony, Germany, and to identify risk factors for being colonized. [METHODS AND RESULTS] Participants were recruited through local press and information events. Detec... | general population; hygiene; infection control; multi-resistant pathogens; multidrug-resistant organisms (MDRO) | 0.774 | 195 | Applied Microbiology and Biotechnology; Biotechnology; Medicine | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,022 |
34,855,690 | Psychotropic Medication Use by Children with Autism Served in Publicly Funded Mental Health Settings. | Journal of developmental and behavioral pediatrics : JDBP | J Dev Behav Pediatr | 43 | 5 | 10.1097/DBP.0000000000001044 | eng | null | null | null | 2,021 | 11 | 30 | [OBJECTIVE] The aim of this study was to characterize patterns of and factors associated with psychotropic medication use in children with autism spectrum disorder (ASD) receiving publicly funded mental health services. [METHOD] Data were extracted from 202 children with ASD participating in a cluster randomized trial ... | null | null | null | null | null | null |
34,855,664 | Translating Phenomenology of Psychogenic Nonepileptic Seizures Into Nosology: Insights From Patients' and Caregivers' Profiles. | The neurologist | Neurologist | 27 | 3 | 10.1097/NRL.0000000000000378 | eng | 2,022 | 5 | 1 | 2,022 | 5 | 1 | [BACKGROUND] Patients with psychogenic nonepileptic seizures (PNES) can be semiologically dichotomized into those with hyperkinetic and those with paucikinetic events. The objective of this study was to compare characteristics of patients with diverse phenomenology and their caregivers to evaluate for differences that ... | null | 0.29 | 68 | Medicine; Neurology | Medicine | 2,022 |
34,855,236 | Affective states and nonsuicidal self-injury (NSSI): Results from an ecological momentary assessment study of veterans with NSSI disorder. | Suicide & life-threatening behavior | Suicide Life Threat Behav | 52 | 2 | 10.1111/sltb.12818 | eng | 2,022 | 4 | null | 2,021 | 12 | 2 | [BACKGROUND] The affective states most strongly associated with nonsuicidal self-injury (NSSI) remain poorly understood, particularly among veterans. This study used ecological momentary assessment (EMA) to examine relationships between affect ratings and NSSI urges and behaviors among veterans with NSSI disorder. [MET... | ecological momentary assessment; emotion; mood; nonsuicidal self-injury; veterans | null | null | null | null | null |
34,855,136 | Long-term Effect of Bariatric Surgery on the Use of Levothyroxine and Thyroid Levels. | Obesity surgery | Obes Surg | 32 | 3 | 10.1007/s11695-021-05810-2 | eng | 2,022 | 3 | null | 2,021 | 12 | 2 | [BACKGROUND] The aim of this study was to evaluate the effect of bariatric surgery on the defined daily dose of levothyroxine (DDD LT4), thyroid-stimulating hormone (TSH), and free thyroxine (fT4) in female patients with hypothyroidism until 48 months after surgery. [METHODS] A retrospective observational study of hypo... | Bariatric surgery; Gastric bypass; Hypothyroidism; Levothyroxine; Sleeve gastrectomy; Thyroid-stimulating hormone | 1.127 | 164 | Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics; Surgery | Medicine; Nursing | 2,022 |
34,854,493 | Is periodontitis a risk factor of benign or malignant colorectal tumor? A population-based cohort study. | Journal of periodontal research | J Periodontal Res | 57 | 2 | 10.1111/jre.12955 | eng | 2,022 | 4 | null | 2,021 | 12 | 2 | [OBJECTIVE] To examine the risk of developing benign or malignant colorectal tumors in patients with periodontitis within 15 years using Taiwan's National Health Insurance Database. [BACKGROUND] Studies have shown that colorectal carcinoma often develops under inflammatory conditions and changes of microbiota in the gu... | benign neoplasms; colorectal tumors; national health programs; periodontitis | 0.816 | 102 | Periodontics | Dentistry | 2,022 |
34,854,481 | Towards a theory of communion-in-caring. | Scandinavian journal of caring sciences | Scand J Caring Sci | 36 | 2 | 10.1111/scs.13049 | eng | 2,022 | 6 | null | 2,021 | 12 | 2 | [BACKGROUND] When nursing practice assumes a fix-it view model, it limits the growing capacity of practice. The theory of communion-in-caring emerged as a hopeful response to the call to offer a new vista. This theory unifies caring and the endless potential of human care. [AIM] The aim of the paper is to describe the ... | caring; caring-in-nursing theories; communion; communion-in-caring | 0.646 | 80 | Public Health, Environmental and Occupational Health | Medicine | 2,022 |
34,854,157 | Randomized controlled pilot trial with ion-exchange water softeners to prevent eczema (SOFTER trial). | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology | Clin Exp Allergy | 52 | 3 | 10.1111/cea.14071 | eng | 2,022 | 3 | null | 2,021 | 12 | 12 | [BACKGROUND] Observational studies suggest an increased risk of eczema in children living in hard versus soft water areas, and there is, therefore, an interest in knowing whether softening water may prevent eczema. We evaluated the feasibility of a parallel-group assessor-blinded pilot randomized controlled trial to te... | atopic eczema; hard water; prevention trial; water softener | 1.166 | 176 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,022 |
34,854,081 | Recurrence of preterm births: A population-based linkage with 3.5 million live births from the CIDACS Birth Cohort. | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics | Int J Gynaecol Obstet | 158 | 3 | 10.1002/ijgo.14053 | eng | 2,022 | 9 | null | 2,021 | 12 | 13 | [OBJECTIVE] To investigate the recurrence of preterm birth (PTB) among the poorest half of the Brazilian population. [METHODS] A population-based retrospective study was conducted in Brazil with the live births of multiparous women extracted from the CIDACS Birth Cohort between 2001 and 2015. We used multivariate logis... | birth cohort; poor populations; preterm birth; recurrent preterm birth | null | null | null | null | null |
34,853,886 | Variations in analgesic, sedation, and delirium management between trauma and non-trauma critically ill children. | Pediatric surgery international | Pediatr Surg Int | 38 | 2 | 10.1007/s00383-021-05039-1 | eng | 2,022 | 2 | null | 2,021 | 12 | 1 | [INTRODUCTION] Studies have shown the benefit of intensive care unit (ICU) bundled protocols; however, they are primarily derived from medical patients. We hypothesized that patients and their medication profiles are different between critically ill medical, surgical, and trauma patients. [METHODS] The Pediatric Health... | Analgesia; Children; Critically ill; Delirium; Sedation; Trauma | 0.575 | 78 | Medicine; Pediatrics, Perinatology and Child Health; Surgery | Medicine | 2,022 |
34,853,857 | A High-Value Care Curriculum Using Individual and Group Structured Reflection. | Southern medical journal | South Med J | 114 | 12 | 10.14423/SMJ.0000000000001325 | eng | 2,021 | 12 | null | null | null | null | [OBJECTIVE] One-third of all healthcare dollars are wasted, primarily in the form of clinician-ordered unnecessary diagnostic tests and treatments. Medical education has likely played a central role in the creation and perpetuation of this problem. We aimed to create a curriculum for medical students to promote their c... | null | null | null | null | null | null |
34,853,539 | Early Benchmarking Total Hip Arthroplasty Implants Using Data from the Michigan Arthroplasty Registry Collaborative Quality Initiative (MARCQI). | Orthopedic research and reviews | Orthop Res Rev | 13 | null | 10.2147/ORR.S325042 | eng | 2,021 | null | null | 2,021 | 11 | 24 | [BACKGROUND] Benchmarking arthroplasty implant revision risk is an informative way to address implant performance. National benchmarking efforts exist in the United Kingdom, Netherlands, and Australia. Recently, the International Prosthesis Benchmarking Working Group, including representatives from industry, academia, ... | arthroplasty; benchmarking; hip; implant; revision | 0.691 | 23 | Orthopedics and Sports Medicine | Medicine | 2,021 |
34,852,983 | Risk of seizure recurrence in people with single seizures and early epilepsy - Model development and external validation. | Seizure | Seizure | 94 | null | 10.1016/j.seizure.2021.11.007 | eng | 2,022 | 1 | null | 2,021 | 11 | 23 | [PURPOSE] Following a single seizure, or recent epilepsy diagnosis, it is difficult to balance risk of medication side effects with the potential to prevent seizure recurrence. A prediction model was developed and validated enabling risk stratification which in turn informs treatment decisions and individualises counse... | Independent data; Newly diagnosed; Prognosis; Risk assessment | 0.868 | 104 | Medicine; Neurology; Neurology | Medicine; Neuroscience | 2,022 |
34,852,754 | Apoptosis in the Dentate Nucleus Following Kindling-induced Seizures in Rats. | CNS neurological disorders drug targets | CNS Neurol Disord Drug Targets | 21 | 6 | 10.2174/1871527320666211201161800 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] Epilepsy is a common neurological disorder characterized by abnormal and recurrent neuronal discharges that result in epileptic seizures. The dentate nuclei of the cerebellum receive excitatory input from different brain regions. Purkinje cell loss due to chronic seizures could lead to decreased inhibition... | Epilepsy; amygdaloid kindling; apoptosis; cerebellum; dentate nucleus; rats | null | null | null | null | null |
34,852,753 | Evaluation of the Antidepressant-like Effect of Chronic Administration of Nigella Fixed Oil Versus Fluoxetine in Rats. | CNS neurological disorders drug targets | CNS Neurol Disord Drug Targets | 21 | 6 | 10.2174/1871527320666211201160001 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] Depression is a group of syndromes characterized by notable and persistent mood disorders, and is one of the most prevalent psychiatric disorders, while the existing treatments have an altered risk-benefit balance. The therapeutic properties of Nigella have been confirmed, suggesting the reliance on phytot... | Nigella sativa; UCMS; antidepressant; depression; fluoxetine; histology | null | null | null | null | null |
34,852,069 | ABO blood group system and occurrence of ischemic stroke. | Arquivos de neuro-psiquiatria | Arq Neuropsiquiatr | 79 | 12 | 10.1590/0004-282X-ANP-2020-0219 | eng | 2,021 | 12 | null | null | null | null | [BACKGROUND] Ischemic stroke (IS) is a multifactorial disease that presents high rates of morbimortality in Brazil. Several studies proved that there is a link between the ABO blood group system and the occurrence of thrombotic events. Nonetheless, its association with IS is not well established. [OBJECTIVE] For that r... | null | 0.427 | 60 | Neurology; Neurology; Biological Psychiatry | Medicine; Neuroscience | 2,021 |
34,851,865 | Honorific Speech Impairment: A Characteristic Sign of Frontotemporal Dementia. | Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology | Cogn Behav Neurol | 34 | 4 | 10.1097/WNN.0000000000000284 | eng | 2,021 | 12 | 2 | 2,021 | 12 | 2 | [BACKGROUND] Individuals with the behavioral variant of frontotemporal dementia (bvFTD) exhibit various levels of abulia, disinhibition, impaired judgment, and decline in executive function. Empirical evidence has shown that individuals with bvFTD also often exhibit difficulty using honorific speech, which expresses re... | null | null | null | null | null | null |
34,851,585 | Oral administration of n-3 fatty acids positively affect the mucosal lesions after experimental ischemic enteritis in the rat. | Cirugia y cirujanos | Cir Cir | 89 | 6 | 10.24875/CIRU.20001023 | eng | 2,021 | null | null | null | null | null | [AIM] The purpose of the study was to evaluate the effect of oral administration of n-3 polyunsaturated fatty acids in experimental ischemic enteritis in rats. [METHODS] Forty Wistar rats were submitted to control narrowing of the superior mesenteric artery and were divided in two groups: N3 polyunsaturated fatty acids... | Citocinas; Cytokines; Immunonutrition; Intestinal ischemia; Intestino delgado; Ischemic enteritis; Isquemia intestinal; N-3 fatty acids; Small bowel | null | null | null | null | null |
34,851,502 | Clinical results of image-guided interstitial brachytherapy with or without external beam radiotherapy for postsurgical vaginal recurrence of cervical and endometrial cancers. | Japanese journal of radiology | Jpn J Radiol | 40 | 6 | 10.1007/s11604-021-01229-y | eng | 2,022 | 6 | null | 2,021 | 12 | 1 | [PURPOSE] This study aimed to evaluate the clinical outcome and efficacy of image-guided interstitial brachytherapy (ISBT) for postsurgical vaginal recurrence of cervical and endometrial cancers. [MATERIALS AND METHODS] The study included 11 patients who received CT-based image-guided high-dose-rate ISBT with or withou... | Brachytherapy; Image-guided brachytherapy; Vaginal recurrence | 0.55 | 53 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,022 |
34,850,613 | Spectral characterization of liquid hemoglobin phantoms with varying oxygenation states. | Journal of biomedical optics | J Biomed Opt | 27 | 7 | 10.1117/1.JBO.27.7.074708 | eng | 2,021 | 12 | null | null | null | null | [SIGNIFICANCE] For optical methods to accurately assess hemoglobin oxygen saturation in vivo, an independently verifiable tissue-like standard is required for validation. For this purpose, we propose three hemoglobin preparations and evaluate methods to characterize them. [AIM] To spectrally characterize three differen... | hemoglobin; oxygen saturation; tissue simulating phantom | 0.872 | 165 | Atomic and Molecular Physics, and Optics; Electronic, Optical and Magnetic Materials; Biomaterials; Biomedical Engineering | Engineering; Materials Science; Physics and Astronomy | 2,021 |
34,850,317 | Clinical investigation of lipopolysaccharide in the persistence of metabolic syndrome (MS) through the activation of GRP78-IRE1α-ASK1 signaling pathway. | Molecular and cellular biochemistry | Mol Cell Biochem | 477 | 2 | 10.1007/s11010-021-04302-2 | eng | 2,022 | 2 | null | 2,021 | 11 | 30 | [OBJECTIVE] Endoplasmic reticulum stress (ERS) might play a pivotal role in the persistence of metabolic syndrome (MS). Lipopolysaccharide (LPS) derived from various gram-negative bacteria could result in the ERS. Therefore, we aimed to investigate the association between LPS and ERS in MS. [METHOD] We enrolled 86 pati... | Endoplasmic reticulum (ER) stress; Inflammation; Insulin resistance; Lipopolysaccharide (LPS) | 0.826 | 140 | Clinical Biochemistry; Medicine; Molecular Biology; Cell Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,849,617 | Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data. | Rheumatology (Oxford, England) | Rheumatology (Oxford) | 61 | 8 | 10.1093/rheumatology/keab870 | eng | 2,022 | 8 | 3 | null | null | null | [OBJECTIVES] International data suggest inflammatory arthritis (IA) pain management frequently involves opioid prescribing, despite little evidence of efficacy, and potential harms. We evaluated analgesic prescribing in English National Health Service-managed patients with IA. [METHODS] Repeated cross-sectional analyse... | analgesics; inflammatory arthritis; opioids; pain | 1.721 | 205 | Pharmacology; Rheumatology | Medicine | 2,022 |
34,849,424 | Recruitment characteristics and non-adherence associated factors of fibromyalgia patients in a randomized clinical trial: A retrospective survival analysis. | Contemporary clinical trials communications | Contemp Clin Trials Commun | 24 | null | 10.1016/j.conctc.2021.100860 | eng | 2,021 | 12 | null | 2,021 | 11 | 17 | [INTRODUCTION] Fibromyalgia is a complex pain condition that affects mostly women. Given the disease's lack of understanding, patients report poor adherence to medication and mistrust of medical services. This study aims to describe the recruitment characteristics and non-adherence associated factors of fibromyalgia pa... | Clinical trials participation; Fibromyalgia; Recruitment; Therapeutic adherence and compliance; Underrepresented population | 0.748 | 30 | Medicine; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,021 |
34,849,393 | The effect of azithromycin for management of HIV-associated chronic lung disease on right heart function: Results from the BREATHE trial. | International journal of cardiology. Heart vasculature | Int J Cardiol Heart Vasc | 37 | null | 10.1016/j.ijcha.2021.100920 | eng | 2,021 | 12 | null | 2,021 | 11 | 20 | [BACKGROUND] Right heart abnormalities and pulmonary hypertension (PH) may be secondary to chronic lung disease. Chronic lung disease is common in children with HIV. In the BREATHE trial (Trial registration: NCT02426112), azithromycin (AZM) reduced the risk of acute respiratory exacerbations in children aged 6-19 years... | Adolescents; Africa; Children; Chronic lung disease; HIV; Right heart | null | null | null | null | null |
34,848,454 | Intravenous Administration of Dehydroxymethylepoxyquinomicin With Polymer Enhances the Inhibition of Pancreatic Carcinoma Growth in Mice. | Anticancer research | Anticancer Res | 41 | 12 | 10.21873/anticanres.15419 | eng | 2,021 | 12 | null | null | null | null | [BACKGROUND/AIM] Pancreatic cancer, which exhibits resistance to cytotoxic and molecular targeted drugs, has an extremely poor prognosis. Nuclear factor-κB (NF-κB) is constitutively activated in many pancreatic cancer cases. Although the NF-κB inhibitor dehydroxymethylepoxyquinomicin (DHMEQ) has exhibited anti-cancer e... | Dehydroxymethylepoxyquinomicin; amphiphilic phospholipid polymer; anti-cancer effects; drug delivery system; pancreatic cancer | null | null | null | null | null |
34,848,018 | Seasonal variation in fall-related emergency department visits by location of fall - United States, 2015. | Journal of safety research | J Safety Res | 79 | null | 10.1016/j.jsr.2021.08.002 | eng | 2,021 | 12 | null | 2,021 | 8 | 18 | [INTRODUCTION] In the United States, fall-related emergency department (ED) visits among older adults (age 65 and older) have increased over the past decade. Studies document seasonal variation in fall injuries in other countries, while research in the United States is inconclusive. The objectives of this study were to... | Elderly; Falls; Indoor; Older adults; Outdoor; Winter | 0.969 | 110 | Safety, Risk, Reliability and Quality | Engineering | 2,021 |
34,847,578 | The Majority of Boys Having Orchidopexy for Congenital Nonsyndromic Cryptorchidism during Minipuberty Exhibited Normal Reproductive Hormonal Profiles. | European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie | Eur J Pediatr Surg | 32 | 1 | 10.1055/s-0041-1739416 | eng | 2,022 | 2 | null | 2,021 | 11 | 30 | [INTRODUCTION] The activation of the hypothalamic-pituitary-gonadal axis that occurs in male minipuberty during the first 5 months of life is important for early germ cell development. Orchidopexy during minipuberty may improve fertility potential as the germinative epithelium may benefit from the naturally occurring g... | null | 0.552 | 58 | Pediatrics, Perinatology and Child Health; Surgery | Medicine | 2,022 |
34,847,317 | Pituicytoma: Four cases with unusual imaging features and a literature review. | Neuro endocrinology letters | Neuro Endocrinol Lett | 42 | 7 | null | eng | 2,021 | 11 | 30 | null | null | null | [OBJECTIVE] Pituicytomas (PTs) are rare and benign neoplasms. The variable imaging and clinical features of PTs, which overlap with other sellar pathologies, can make preoperative diagnosis challenging. In the interest of a more comprehensive understanding of the diagnostic aspects of PTs, it is necessary to report and... | null | null | null | null | null | null |
34,847,264 | Specific dento-craniofacial characteristics in non-syndromic children can predispose to sleep-disordered breathing. | Acta paediatrica (Oslo, Norway : 1992) | Acta Paediatr | 111 | 3 | 10.1111/apa.16202 | eng | 2,022 | 3 | null | 2,021 | 12 | 7 | [AIM] To ascertain and illustrate specific clinical dento-craniofacial characteristics associated with sleep-disordered breathing (SDB) in non-syndromic children. [METHODS] Narrative review of literature on SDB, dental occlusion and craniofacial morphology retrieved through online literature database search for these t... | airway; children; craniofacial morphology; dental occlusion; sleep-disordered breathing | null | null | null | null | null |
34,847,230 | Potemkin Protections: Assessing Provider Directory Accuracy and Timely Access for Four Specialties in California. | Journal of health politics, policy and law | J Health Polit Policy Law | 47 | 3 | 10.1215/03616878-9626866 | eng | 2,022 | 6 | 1 | null | null | null | [CONTEXT] The accuracy of provider directories and whether consumers can schedule timely appointments are crucial determinants of health access and outcomes. [METHODS] We evaluated accuracy and timely access data obtained from the California Department of Managed Health Care, consisting of responses to large, random, r... | California; consumer access; provider directories; provider directory inaccuracies | null | null | null | null | null |
34,846,912 | Medical Outcomes of Oncology Inpatients With and Without Chaplain Spiritual Care Visit: The Yale New Haven Hospital Experience. | JCO oncology practice | JCO Oncol Pract | 18 | 3 | 10.1200/OP.21.00600 | eng | 2,022 | 3 | null | 2,021 | 11 | 30 | [PURPOSE] Although there exists some literature on the psychosocial elements of health between patients with and without spiritual care, less information is available on hospital health outcomes. Hence, we aimed to describe and compare health care utilization and outcomes among medical oncology patients who received an... | null | 1.349 | 85 | Health Policy; Oncology; Oncology | Medicine; Nursing | 2,022 |
34,846,304 | Trends in Remote Health Care Consumption in Sweden: Comparison Before and During the First Wave of the COVID-19 Pandemic. | JMIR human factors | JMIR Hum Factors | 9 | 1 | 10.2196/33034 | eng | 2,022 | 2 | 2 | 2,022 | 2 | 2 | [BACKGROUND] Remote assessment of respiratory tract infections (RTIs) has been a controversial topic during the fast development of private telemedicine providers in Swedish primary health care. The possibility to unburden the traditional care has been put against a questionable quality of care as well as risks of incr... | COVID-19; primary health care; remote health care; respiratory tract infections; telemedicine | 0.802 | 36 | Health Informatics; Human Factors and Ergonomics | Medicine; Social Sciences | 2,022 |
34,846,050 | Application of closed kinematic chain exercises with eccentric and strength exercises for the shoulder injuries prevention in student rock climbers: a randomized controlled trial. | Acta of bioengineering and biomechanics | Acta Bioeng Biomech | 23 | 2 | null | eng | 2,021 | null | null | null | null | null | [PURPOSE] The aim of this work to determine the influence of a program containing exercises in a closed kinematic chain, eccentric and strength exercises on injuries of students - rock climbers. [METHODS] Participants in this study were 84 male amateur climbing students, aged 18-19, 40 athletes were in the intervention... | null | null | null | null | null | null |
34,846,047 | Differentiating fallers from nonfallers using nonlinear variability analyses of data from a low-cost portable footswitch device: a feasibility study. | Acta of bioengineering and biomechanics | Acta Bioeng Biomech | 23 | 2 | null | eng | 2,021 | null | null | null | null | null | [PURPOSE] Falls are one of the main causes of injuries in older adults. This study evaluated a low-cost footswitch device that was designed to measure gait variability and investigates whether there are any relationships between variability metrics and clinical balance tests for individuals with a history of previous f... | null | null | null | null | null | null |
34,845,949 | Catechin regulates miR-182/GGPPS1 signaling pathway and inhibits LPS-induced acute lung injury in mice. | Immunopharmacology and immunotoxicology | Immunopharmacol Immunotoxicol | 44 | 1 | 10.1080/08923973.2021.2002890 | eng | 2,022 | 2 | null | 2,021 | 11 | 30 | [AIM] Acute lung injury (ALI) and resultant acute respiratory distress syndrome (ARDS) are detrimental inflammatory disease associated with high rates of morbidity and mortality due to a lack of effective treatment options. Previous study has demonstrated that an inhibition of geranylgeranyl pyrophosphate synthase larg... | Catechin; GGPPS1; acute lung injury; inflammasome; miR-182 | 0.594 | 63 | Medicine; Pharmacology; Toxicology; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,022 |
34,845,773 | Elucidation of double-bond positions of polyunsaturated alkenes through gas chromatography/mass spectrometry analysis of mono-dimethyl disulfide derivatives. | Rapid communications in mass spectrometry : RCM | Rapid Commun Mass Spectrom | 36 | 3 | 10.1002/rcm.9228 | eng | 2,022 | 2 | 15 | null | null | null | [RATIONALE] Derivatization with dimethyl disulfide (DMDS) followed by gas chromatography/mass spectrometry (GC/MS) analysis is a well-established method for locating double-bond position on the alkyl chain of mono-unsaturated compounds such as alkenes. For alkenes containing more than one double bond, however, the conv... | null | 0.423 | 152 | Analytical Chemistry; Organic Chemistry; Spectroscopy | Chemistry | 2,022 |
34,845,546 | Safety and effectiveness of laparoscopic intratumoral resection facilitated by coagulation of giant hepatic hemangioma: a matched case-control study and literature review. | Surgical endoscopy | Surg Endosc | 36 | 7 | 10.1007/s00464-021-08891-3 | eng | 2,022 | 7 | null | 2,021 | 11 | 29 | [BACKGROUND] To report the safety and effectiveness of laparoscopic intratumoral resection facilitated by coagulation (LIRC) compared with laparoscopic hepatectomy (LH) in treating giant hepatic hemangioma. [METHODS] From 2017 to 2020, 19 consecutive patients with giant hepatic hemangioma (≥ 10 cm) received LIRC in one... | Coagulation; Giant hepatic hemangioma; Laparoscopic intratumoral resection | 1.124 | 178 | Surgery | Medicine | 2,022 |
34,844,922 | Risk prediction models for symptomatic patients with bladder and kidney cancer: a systematic review. | The British journal of general practice : the journal of the Royal College of General Practitioners | Br J Gen Pract | 72 | 714 | 10.3399/BJGP.2021.0319 | eng | 2,022 | 1 | null | 2,021 | 12 | 31 | [BACKGROUND] Timely diagnosis of bladder and kidney cancer is key to improving clinical outcomes. Given the challenges of early diagnosis, models incorporating clinical symptoms and signs may be helpful to primary care clinicians when triaging at-risk patients. [AIM] To identify and compare published models that use cl... | bladder cancer; early diagnosis; kidney cancer; risk prediction; systematic review | 1.145 | 125 | Family Practice; Medicine | Medicine | 2,022 |
34,844,888 | Evaluation of osseous changes in dental panoramic radiography using radiomorphometric indices in patients with hyperthyroidism. | Oral surgery, oral medicine, oral pathology and oral radiology | Oral Surg Oral Med Oral Pathol Oral Radiol | 133 | 4 | 10.1016/j.oooo.2021.10.011 | eng | 2,022 | 4 | null | 2,021 | 10 | 23 | [OBJECTIVE] The aim of the present study was to compare radiomorphometric measurements on panoramic images of patients with hyperthyroidism (HT) to those of a control population. [STUDY DESIGN] In this retrospective study, the mental index (MI), inferior panoramic mandibular index (PMI), antegonial index (AI), gonial i... | null | 0.561 | 145 | Dentistry; Oral Surgery; Pathology and Forensic Medicine; Radiology, Nuclear Medicine and Imaging; Surgery | Dentistry; Medicine | 2,022 |
34,844,812 | Antidepressant decision aid for major depressive disorder patients (ADAM): Development and pilot testing. | Patient education and counseling | Patient Educ Couns | 105 | 7 | 10.1016/j.pec.2021.11.007 | eng | 2,022 | 7 | null | 2,021 | 11 | 20 | [OBJECTIVES] This study aimed to develop and assess the effectiveness of an encounter decision aid for Malaysian patients with MDD to support treatment decision-making during the consultation. [METHODS] The decision aid prototype was developed following a literature review and six focus groups. Alpha testing assessed i... | Antidepressant decision aid; Collaborative care; Depression; Major depressive disorder; Patient-centered care; Shared decision making | 1 | 168 | Medicine | Medicine | 2,022 |
34,844,783 | Negative silence in the classroom: A cross-sectional study of undergraduate nursing students. | Nurse education today | Nurse Educ Today | 109 | null | 10.1016/j.nedt.2021.105221 | eng | 2,022 | 2 | null | 2,021 | 11 | 13 | [OBJECTIVE] To investigate the concept of negative silent behavior of undergraduate nursing students and its influencing factors. [METHODS] A cross sectional study was conducted by using convenience sampling, and 269 nursing students enrolled from August-September 2021 in a higher medical institution in Guizhou Provinc... | Classroom silence; Influencing factors; Undergraduate nursing students | 0.946 | 109 | Education; Nursing | Nursing; Social Sciences | 2,022 |
34,844,631 | Psychosocial wellbeing among children and adults with arthrogryposis: a scoping review. | Health and quality of life outcomes | Health Qual Life Outcomes | 19 | 1 | 10.1186/s12955-021-01896-5 | eng | 2,021 | 11 | 29 | 2,021 | 11 | 29 | [BACKGROUND] Arthrogryposis multiplex congenita (AMC) is a group of congenital conditions characterized by joint contractures in two or more body areas. Management of AMC starts early in life and focuses on improving mobility and function through intensive rehabilitation and surgical interventions. Psychosocial wellbei... | Arthrogryposis multiplex congenita; Outcome measures; Psychosocial wellbeing; Quality of life | 0.837 | 144 | Public Health, Environmental and Occupational Health; Medicine | Medicine | 2,021 |
34,844,568 | Prognostic value of preoperative peripheral blood mean platelet volume/platelet count ratio (MPV/PC) in patients with resectable cervical cancer. | BMC cancer | BMC Cancer | 21 | 1 | 10.1186/s12885-021-09016-8 | eng | 2,021 | 11 | 29 | 2,021 | 11 | 29 | [BACKGROUND] The mean platelet volume/platelet count ratio (MPV/PC) ratio based on the preoperative peripheral MPV and PCcan be used to predict the prognosis of multiple malignant tumors. [OBJECTIVE] To evaluate the prognostic value of MPV/PC in cervical cancer patients. [METHODS] This study enrolled 408 patients who h... | Cervical cancer; MPV/PC; Nomogram; Prognosis | 1.134 | 171 | Cancer Research; Genetics; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
34,844,546 | GreenMolBD: Nature Derived Bioactive Molecules' Database. | Medicinal chemistry (Shariqah (United Arab Emirates)) | Med Chem | 18 | 6 | 10.2174/1573406418666211129103458 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] One of the essential resources for developing new drugs are naturally derived biologically active lead compounds. Biomedical researchers and pharmaceutical companies are highly interested in these plant-derived molecules to develop the new drug. In this process, collective information of the plants and the... | Bangladeshi plant database; Plant database; compound database; in silico properties; natural products; pharmacological evidence | null | null | null | null | null |
34,843,957 | Implementation of a prospective study for enhancing surveillance of invasive bacterial infections in North Africa. | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases | Int J Infect Dis | 115 | null | 10.1016/j.ijid.2021.11.036 | eng | 2,022 | 2 | null | 2,021 | 11 | 27 | [OBJECTIVES] We implemented a project named MENINGSTOP in three countries of North Africa (Algeria, Morocco and Tunisia). The main objective was to use real-time PCR to detect, identify and type the three main agents (Neisseria meningitidis, Streptococcus pneumoniae and Haemophilus influenzae) responsible for invasive ... | Algeria; Invasive bacterial infections; Morocco; Quality assurance; Tunisia; real-time PCR; surveillance | 2.006 | 140 | Infectious Diseases; Medicine; Microbiology | Medicine | 2,022 |
34,843,819 | Annular size and interaction with trans-catheter aortic valves for treatment of severe bicuspid aortic valve stenosis: Insights from the BEAT registry. | International journal of cardiology | Int J Cardiol | 349 | null | 10.1016/j.ijcard.2021.11.055 | eng | 2,022 | 2 | 15 | 2,021 | 11 | 26 | [BACKGROUND] Transcatheter aortic valve replacement (TAVR) is safe and feasible in patients with bicuspid aortic valve (BAV), but whether annular size may influence TAVR results in BAV patients remains unclear. We aimed at evaluating the impact of aortic annular size on procedural and clinical outcomes of BAV patients ... | Annulus dimensions; Balloon expandable valves; Bicuspid aortic valve; Self-expanding valve; Severe aortic stenosis; Trans-catheter valve replacement | 1.122 | 155 | Cardiology and Cardiovascular Medicine | Medicine | 2,022 |
34,843,761 | Cold temperature and sudden temperature drop as novel risk factors of asthma exacerbation: a longitudinal study in 18 Chinese cities. | The Science of the total environment | Sci Total Environ | 814 | null | 10.1016/j.scitotenv.2021.151959 | eng | 2,022 | 3 | 25 | 2,021 | 11 | 27 | [BACKGROUND] Few studies have explored the role of ambient temperature in asthma exacerbation. [OBJECTIVE] We aimed to explore the association of temperature with diurnal peak expiratory flow (PEF) variation and asthma exacerbation. [METHOD] We developed a longitudinal study among asthmatic adults in 18 Chinese cities.... | Asthma exacerbation; Cold temperature; PEF variation; Temperature variability | 1.946 | 399 | Environmental Chemistry; Environmental Engineering; Pollution; Waste Management and Disposal | Environmental Science | 2,022 |
34,843,511 | Impact of chronic obstructive pulmonary disease on survival and neurologic outcomes in adults with in-hospital cardiac arrest. | PloS one | PLoS One | 16 | 11 | 10.1371/journal.pone.0259698 | eng | 2,021 | null | null | 2,021 | 11 | 29 | [BACKGROUND] Little data exists regarding the association of chronic obstructive pulmonary disease (COPD) on outcomes in the setting of in-hospital cardiac arrest (IHCA). We sought to assess the impact of COPD on mortality and neurologic outcomes in adults with IHCA. [METHODS] The study population included 593 consecut... | null | 0.852 | 467 | Multidisciplinary | Multidisciplinary | 2,021 |
34,843,422 | Effect of 4-Allyl-1-hydroxy-2-methoxybenzene (eugenol) in the expression of genes involved in cellular cycle and apoptotic process in dental pulp fibroblasts. | Acta odontologica Scandinavica | Acta Odontol Scand | 80 | 5 | 10.1080/00016357.2021.2009027 | eng | 2,022 | 7 | null | 2,021 | 11 | 29 | [OBJECTIVE] This study sought to evaluate the effect of eugenol on the cell morphology and expression of genes involved in the apoptotic process in human dental pulp fibroblasts (hDPFs) from deciduous teeth. [MATERIALS AND METHODS] hDPFs were cultured with 4 concentrations of eugenol (0.06 nM, 0.6 nM, 6 nM, 12 nM) and ... | Eugenol; apoptotic genes; cellular cycle; cytotoxicity; dental pulp fibroblasts | 0.506 | 81 | Dentistry; Medicine | Dentistry; Medicine | 2,022 |
34,842,925 | Association of Environmental Uncertainty With Altered Decision-making and Learning Mechanisms in Youths With Obsessive-Compulsive Disorder. | JAMA network open | JAMA Netw Open | 4 | 11 | 10.1001/jamanetworkopen.2021.36195 | eng | 2,021 | 11 | 1 | 2,021 | 11 | 1 | [IMPORTANCE] Adults with obsessive-compulsive disorder (OCD) display perseverative behavior in stable environments but exhibit vacillating choice when payoffs are uncertain. These findings may be associated with intolerance of uncertainty and compulsive behaviors; however, little is known about the mechanisms underlyin... | null | 4.031 | 154 | Medicine | Medicine | 2,021 |
34,842,564 | Marfan Syndrome Presenting as Spontaneous Coronary Artery Dissection and Arteriopathy. | The neurologist | Neurologist | 27 | 1 | 10.1097/NRL.0000000000000358 | eng | 2,021 | 11 | 26 | 2,021 | 11 | 26 | [INTRODUCTION] Spontaneous coronary artery dissection (SCAD) is a term used to define a spontaneous separation of the coronary artery wall not related to underlying risk factors, such as trauma or underlying atherosclerotic disease. While SCAD has a range of different etiologies, with fibromuscular dysplasia being the ... | null | 0.401 | 68 | Medicine; Neurology | Medicine | 2,021 |
34,842,556 | Self-directed Technology-Based Therapeutic Methods for Adult Patients Receiving Mental Health Services: Systematic Review. | JMIR mental health | JMIR Ment Health | 8 | 11 | 10.2196/27404 | eng | 2,021 | 11 | 26 | 2,021 | 11 | 26 | [BACKGROUND] Technological interventions used to treat illnesses and promote health are grouped under the umbrella term of digital therapeutics. The use of digital therapeutics is becoming increasingly common in mental health. Although many technologies are currently being implemented, research supporting their usabili... | digital therapeutics; internet; mental health; mobile applications; mobile phone; self-directed; technology; telehealth; telemedicine | 1.365 | 68 | Psychiatry and Mental Health | Medicine | 2,021 |
34,842,358 | Health-related quality of life and parental depression in children with pulmonary arterial hypertension. | Pediatric pulmonology | Pediatr Pulmonol | 57 | 2 | 10.1002/ppul.25777 | eng | 2,022 | 2 | null | 2,021 | 12 | 3 | [BACKGROUND] Impaired health-related quality of life (HRQoL) is a common problem in pulmonary arterial hypertension (PAH), but there is limited data on HRQoL in children with PAH. We aimed to investigate the QoL, determine the potential risk factors for poor HRQoL in children with PAH, and assess the depression and anx... | KINDL-R; children; depression; pulmonary arterial hypertension; quality of life | 0.909 | 125 | Pediatrics, Perinatology and Child Health; Pulmonary and Respiratory Medicine | Medicine | 2,022 |
34,842,215 | Mindfulness meditation training in an occupational setting: Effects of a 12-weeks mindfulness-based intervention on wellbeing. | Work (Reading, Mass.) | Work | 70 | 4 | 10.3233/WOR-210510 | eng | 2,021 | null | null | null | null | null | [BACKGROUND] Mindfulness-based interventions (MBIs) are known for their beneficial effects on positive and negative psychological factors. When applied in an occupational context, MBIs might help workers to cope with stress, increase their professional outcomes and wellbeing. [OBJECTIVE] In this two-groups pre-post exp... | Mindfulness-based interventions; healthy subjects; psychological wellbeing; questionnaires; workplace | null | null | null | null | null |
34,842,194 | Stochastic Epigenetic Mutations Influence Parkinson's Disease Risk, Progression, and Mortality. | Journal of Parkinson's disease | J Parkinsons Dis | 12 | 2 | 10.3233/JPD-212834 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] Stochastic epigenetic mutations (SEM) reflect a deviation from normal site-specific methylation patterns. Epigenetic mutation load (EML) captures the accumulation of SEMs across an individual's genome and may reflect dysfunction of the epigenetic maintenance system in response to epigenetic challenges. [OB... | epigenetics | 1.325 | 75 | Neurology; Cellular and Molecular Neuroscience | Medicine; Neuroscience | 2,022 |
34,841,722 | A screening assistance system for cervical cytology of squamous cell atypia based on a two-step combined CNN algorithm with label smoothing. | Cancer medicine | Cancer Med | 11 | 2 | 10.1002/cam4.4460 | eng | 2,022 | 1 | null | 2,021 | 11 | 28 | [BACKGROUND] Although many cervical cytology diagnostic support systems have been developed, it is challenging to classify overlapping cell clusters with a variety of patterns in the same way that humans do. In this study, we developed a fast and accurate system for the detection and classification of atypical cell clu... | ResNeSt; You Only Look Once (YOLO); cervical cytology; deep learning; machine learning | 1.188 | 95 | Oncology; Radiology, Nuclear Medicine and Imaging; Cancer Research | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,840,976 | The Relationship between Aeroallergen Sensitization and Chronic Cough in School-Aged Children from General Population. | BioMed research international | Biomed Res Int | 2021 | null | 10.1155/2021/5513611 | eng | 2,021 | null | null | 2,021 | 11 | 18 | [OBJECTIVE] Determining sensitivity to allergens is an essential step in diagnosing children with allergic diseases. Chronic cough has remained poorly understood with causative triggers. The purpose of our study was to shed light on the relationship between sensitization to aeroallergens and chronic cough. [METHODS] Th... | null | 0.647 | 203 | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,021 |
34,840,686 | Atopobiosis and Dysbiosis in Ocular Diseases: Is Fecal Microbiota Transplant and Probiotics a Promising Solution? | Journal of ophthalmic vision research | J Ophthalmic Vis Res | 16 | 4 | 10.18502/jovr.v16i4.9754 | eng | 2,021 | null | null | 2,021 | 10 | 25 | [PURPOSE] To highlight the role of atopobiosis and dysbiosis in the pathomechanism of autoimmune uveitis, therefore supporting fecal microbiota transplant (FMT) and probiotics as potential targeted-treatment for uveitis. [METHODS] This review synthesized literatures upon the relation between gut microbiota, autoimmune ... | Autoimmune; Dysbiosis; Uveitis; Atopobiosis | null | null | null | null | null |
34,840,066 | Acute surgical admissions at the end of life-an analysis of non-operative hospital deaths. | The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland | Surgeon | 20 | 6 | 10.1016/j.surge.2021.09.003 | eng | 2,022 | 12 | null | 2,021 | 11 | 26 | [BACKGROUND] Patients with advanced illnesses are often admitted with acute surgical emergencies. There is currently no evidence characterising such admissions. We aimed to evaluate emergency patients, managed non-operatively, who died during the same admission. [METHODS] This single-centre retrospective, observational... | ASA; Acute surgical admissions; Charlson comorbidity index; End of life care; Frailty; Non-operative deaths | 0.607 | 68 | Surgery | Medicine | 2,022 |
34,840,004 | Association between behavioural risk factors and metabolic syndrome among adult population in India: A systematic review and meta-analysis of observational studies. | Nutrition, metabolism, and cardiovascular diseases : NMCD | Nutr Metab Cardiovasc Dis | 32 | 1 | 10.1016/j.numecd.2021.09.006 | eng | 2,022 | 1 | null | 2,021 | 9 | 16 | [AIMS] The impact of behavioural risk factors on the metabolic syndrome has not been well understood by the researchers. This information is important to the policymakers for developing effective strategies and implement relevant policies or programs. Hence, we undertook this meta-analysis to estimate the effect of beh... | Alcohol; Metabolic syndrome; Physical activity; Smoking | 0.997 | 125 | Cardiology and Cardiovascular Medicine; Medicine; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism | Medicine; Nursing | 2,022 |
34,839,949 | Laparoscopic inguinal herniotomy: Recreating the open operation optimises outcomes. | Journal of pediatric surgery | J Pediatr Surg | 57 | 2 | 10.1016/j.jpedsurg.2021.10.042 | eng | 2,022 | 2 | null | 2,021 | 10 | 30 | [BACKGROUND] Recent evidence suggests simple laparoscopic inguinal herniorrhaphy is associated with higher rates of recurrence and testicular ascent. We instigated a standardised approach to laparoscopic inguinal herniotomy (LIH), with circumferential sac division and 'purse-string' closure (4/0 monofilament polypropyl... | Hernia; Herniotomy; Inguinal; Laparoscopic; Outcomes | 0.873 | 147 | Medicine; Pediatrics, Perinatology and Child Health; Surgery | Medicine | 2,022 |
34,839,763 | Is vaccination necessary for COVID-19 patients? A retrospective cohort study investigating reinfection rates and symptomatology in a tertiary hospital. | Expert review of vaccines | Expert Rev Vaccines | 21 | 2 | 10.1080/14760584.2022.2012457 | eng | 2,022 | 2 | null | 2,021 | 12 | 7 | [BACKGROUND] Durability of immune response by the COVID-19 natural infection and the necessity of vaccines in recovered patients are important inquiries for the healthcare provider. [RESEARCH DESIGN AND METHODS] Here, we investigated the characteristics and the rate of cases with reinfection that have been admitted to ... | COVID-19; SARS-COV-2; reinfection; vaccination; vaccine | 1.346 | 112 | Drug Discovery; Molecular Medicine; Pharmacology; Immunology | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Pharmacology, Toxicology and Pharmaceutics | 2,022 |
34,839,726 | Physician-Modified Endograft With Triple Inner Branches for Extensive Aortic Arch Aneurysm. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists | J Endovasc Ther | 29 | 4 | 10.1177/15266028211059439 | eng | 2,022 | 8 | null | 2,021 | 11 | 27 | [PURPOSE] The purpose of this case report was to demonstrate the feasibility of a physician-modified endograft (PMEG) with 3 inner branches for extensive aortic arch aneurysm. [CASE REPORT] A 69-year-old male presented with extensive aortic arch aneurysm involving all supra-aortic vessels. An Ankura thoracic stent graf... | aortic arch aneurysm; branched stent graft; fenestrated stent graft; inner branches; physician-modified endograft; thoracic endovascular aortic repair | 1.114 | 112 | Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging; Surgery | Medicine | 2,022 |
34,839,622 | Comparison of Two pMDIs in Adult Asthmatics: A Randomized Double-Blind Double-Dummy Clinical Trial. | Tuberculosis and respiratory diseases | Tuberc Respir Dis (Seoul) | 85 | 1 | 10.4046/trd.2021.0093 | eng | 2,022 | 1 | null | 2,021 | 11 | 29 | [BACKGROUND] Only a few studies directly compared the therapeutic efficacy and safety of two pressurized metered-dose inhalers (pMDIs) in asthma. We analyzed the asthma treatment outcomes, safety, and patient preferences using formoterol/beclomethasone (FORM/BDP), a pMDI with extra-fine particles, compared with formote... | Asthma; Metered-Dose Inhalers; Particle Size; Preference; Treatment Outcome | 0.689 | 37 | Infectious Diseases; Pulmonary and Respiratory Medicine | Medicine | 2,022 |
34,839,540 | The anti-fatigue activity of corn peptides and their effect on gut bacteria. | Journal of the science of food and agriculture | J Sci Food Agric | 102 | 8 | 10.1002/jsfa.11693 | eng | 2,022 | 6 | null | 2,021 | 12 | 16 | [BACKGROUND] Corn peptides (CPs) are rich in branched-chain amino acids such as leucine and have a variety of biological activities such as antioxidant and improved lipid distribution. In this article, we prepared CPs by enzymatic digestion of corn proteins and evaluated their anti-fatigue activity. [RESULTS] We evalua... | anti-fatigue; corn peptides; exhaustion swim; gut bacteria | null | null | null | null | null |
34,839,256 | Effect of kaempferol on hedgehog signaling pathway in rats with --chronic atrophic gastritis - Based on network pharmacological screening and experimental verification. | Biomedicine pharmacotherapy = Biomedecine pharmacotherapie | Biomed Pharmacother | 145 | null | 10.1016/j.biopha.2021.112451 | eng | 2,022 | 1 | null | 2,021 | 11 | 25 | [OBJECTIVE] The effect of active ingredients of Chaishaoliujun Decoction (CD) on chronic atrophic gastritis (CAG) was screened by network pharmacological method and verified by preliminary experiment. [METHODS] Firstly, the active ingredients and drug targets of CD were retrieved in TCMSP database; CAG-related targets ... | CD; Chronic atrophic gastritis; Hedgehog signaling pathway; Kaempferol; Network pharmacology | null | null | null | null | null |
34,838,453 | Mitral Valve Regurgitation After Lung Transplantation: Aetiology, Management and Outcome. | Heart, lung circulation | Heart Lung Circ | 31 | 5 | 10.1016/j.hlc.2021.10.010 | eng | 2,022 | 5 | null | 2,021 | 11 | 24 | [BACKGROUND] Problematic mitral regurgitation (MR) may develop following lung transplantation (LTx). There is limited information on the management of MR in LTx patients, as such we sought to evaluate our centre's experience. [METHODS] From 2000 to 2019, 1,054 patients underwent LTx at our centre (896 bilateral, 158 si... | Cardiac surgery; Lung transplantation; Mitral valve regurgitation; Pulmonary hypertension | null | null | null | null | null |
34,838,396 | Limited Impact of Breast Cancer and Non-breast Malignancies on Survival in Older Patients with Early-Stage Breast Cancer: Results of a Large, Single-Centre, Population-Based Study. | Clinical oncology (Royal College of Radiologists (Great Britain)) | Clin Oncol (R Coll Radiol) | 34 | 6 | 10.1016/j.clon.2021.11.005 | eng | 2,022 | 6 | null | 2,021 | 11 | 24 | [AIMS] To analyse the disease-free survival and overall survival in older adults with breast cancer after breast-conserving therapy, focusing on the relevance of non-breast malignancy (NBM) with respect to survival rates. [MATERIALS AND METHODS] Analyses were based on 1205 women aged 65 years and older with breast canc... | Breast cancer; older adults; population-based study; second malignancy; survival | 1.019 | 94 | Radiology, Nuclear Medicine and Imaging; Oncology | Medicine | 2,022 |
34,838,023 | Molecular prevalence and risk factors associated with tick-borne pathogens in cattle in western Kenya. | BMC veterinary research | BMC Vet Res | 17 | 1 | 10.1186/s12917-021-03074-7 | eng | 2,021 | 11 | 27 | 2,021 | 11 | 27 | [BACKGROUND] Tick-borne pathogens (TBPs) are of global importance, especially in sub-Saharan Africa where they represent a major constraint to livestock production. Their association with human disease is also increasingly recognized, signalling their zoonotic importance. It is therefore crucial to investigate TBPs pre... | Anaplasma; Dual infection; Livestock markets; Slaughterhouses; Theileria; Western Kenya | 0.65 | 86 | Veterinary; Medicine | Medicine; Veterinary | 2,021 |
34,838,000 | Bioinformatics prediction and experimental verification identify MAD2L1 and CCNB2 as diagnostic biomarkers of rhabdomyosarcoma. | Cancer cell international | Cancer Cell Int | 21 | 1 | 10.1186/s12935-021-02347-3 | eng | 2,021 | 11 | 27 | 2,021 | 11 | 27 | [BACKGROUND] Rhabdomyosarcoma (RMS) is a malignant soft-tissue tumour. In recent years, the tumour microenvironment (TME) has been reported to be associated with the development of tumours. However, the relationship between the occurrence and development of RMS and TME is unclear. The purpose of this study is to identi... | Bioinformatics; CCNB2; MAD2L1; Rhabdomyosarcoma; The tumor microenvironment | 1.099 | 90 | Cancer Research; Genetics; Oncology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,021 |
34,837,948 | EvalDNA: a machine learning-based tool for the comprehensive evaluation of mammalian genome assembly quality. | BMC bioinformatics | BMC Bioinformatics | 22 | 1 | 10.1186/s12859-021-04480-2 | eng | 2,021 | 11 | 27 | 2,021 | 11 | 27 | [BACKGROUND] To select the most complete, continuous, and accurate assembly for an organism of interest, comprehensive quality assessment of assemblies is necessary. We present a novel tool, called Evaluation of De Novo Assemblies (EvalDNA), which uses supervised machine learning for the quality scoring of genome assem... | CHO cells; Chinese hamster; Genome assembly; Genome assembly quality; Machine learning | 1.246 | 251 | Applied Mathematics; Biochemistry; Computer Science Applications; Molecular Biology; Structural Biology | Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics | 2,021 |
34,837,942 | A multitask transfer learning framework for the prediction of virus-human protein-protein interactions. | BMC bioinformatics | BMC Bioinformatics | 22 | 1 | 10.1186/s12859-021-04484-y | eng | 2,021 | 11 | 27 | 2,021 | 11 | 27 | [BACKGROUND] Viral infections are causing significant morbidity and mortality worldwide. Understanding the interaction patterns between a particular virus and human proteins plays a crucial role in unveiling the underlying mechanism of viral infection and pathogenesis. This could further help in prevention and treatmen... | Human PPI; Multitask; Protein embedding; Transfer learning; Virus-human PPI | 1.246 | 251 | Applied Mathematics; Biochemistry; Computer Science Applications; Molecular Biology; Structural Biology | Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics | 2,021 |
34,837,773 | Walking through an aperture while penetrating from the paretic side improves safety managing the paretic side for individuals with stroke who had previous falls. | Human movement science | Hum Mov Sci | 81 | null | 10.1016/j.humov.2021.102906 | eng | 2,022 | 2 | null | 2,021 | 11 | 24 | [BACKGROUND] Safety management of the paretic side of the body is critical for individuals with stroke. We previously reported that individuals with stroke who walk through an aperture while penetrating from the paretic side had fewer collisions with the frame of an aperture than did those penetrating from the non-pare... | Adaptive locomotion; Obstacle avoidance; Previous falls; Stroke; Walking through apertures | null | null | null | null | null |
34,837,713 | Long non-coding RNA MIR31HG as a prognostic predictor for malignant cancers: A meta- and bioinformatics analysis. | Journal of clinical laboratory analysis | J Clin Lab Anal | 36 | 1 | 10.1002/jcla.24082 | eng | 2,022 | 1 | null | 2,021 | 11 | 27 | [BACKGROUND] The possible regulatory mechanism of MIR31HG in human cancers remains unclear, and reported results of the prognostic significance of MIR31HG expression are inconsistent. [METHODS] The meta-analysis and related bioinformatics analysis were conducted to evaluate the role of MIR31HG in tumor progression. [RE... | MIR31HG; bioinformatics analysis; cancer; meta-analysis; prognostic biomarker | 0.594 | 67 | Medical Laboratory Technology; Biochemistry; Clinical Biochemistry; Public Health, Environmental and Occupational Health; Hematology; Immunology and Allergy; Microbiology | Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine | 2,022 |
34,837,626 | Production of transgenic Allium cepa by nanoparticles to resist Aspergillus niger infection. | Molecular biology reports | Mol Biol Rep | 49 | 3 | 10.1007/s11033-021-06988-5 | eng | 2,022 | 3 | null | 2,021 | 11 | 27 | [BACKGROUND] Transgenic plants are becoming a more powerful tool in modern biotechnology. Genetic engineering was used in biotech-derived products to create genetically modified (GM) plants resistant to diseases. The onion (Allium cepa, L.) is a common, important perennial vegetable crop grown in Egypt for food and eco... | Allium cepa; Aspergillus niger; Chitosan nanoparticles; Thionin; Transformation | 0.578 | 96 | Medicine; Genetics; Molecular Biology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,022 |
34,837,524 | The effect of flaxseed with or without anti-inflammatory diet in patients with rheumatoid arthritis, a randomized controlled trial. | European journal of nutrition | Eur J Nutr | 61 | 3 | 10.1007/s00394-021-02707-9 | eng | 2,022 | 4 | null | 2,021 | 11 | 27 | [PURPOSE] Beneficial effect of long-chain ω-3 fatty acids against symptoms of rheumatoid arthritis (RA) has been indicated in previous studies. We examined the effect of flaxseed and anti-inflammatory diet in patients with RA. [METHODS] The 12-week intervention was performed on 120 patients with RA who were randomized ... | Anti-inflammatory diet; DAS28; Flaxseed; Pain; Quality of life; Rheumatoid arthritis | 1.094 | 125 | Medicine; Nutrition and Dietetics | Medicine; Nursing | 2,022 |
34,837,500 | Evaluating vagus nerve stimulation treatment with heart rate monitoring in pediatric patients with intractable epilepsy. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery | Childs Nerv Syst | 38 | 3 | 10.1007/s00381-021-05416-0 | eng | 2,022 | 3 | null | 2,021 | 11 | 27 | [PURPOSE] Vagus nerve stimulators (VNS) have emerged as an effective treatment modality for pediatric patients suffering from intractable, drug-resistant epilepsy. Newer devices, AspireSR™ Model 106 and the SenTiva™ Model 1000 (VNS TherapyⓇ, LivaNova™), contain an "auto-stimulation" feature that detects ictal tachycard... | Aspire; Autostimulation; Intractable epilepsy; Sentiva; Vagus nerve stimulation | 0.504 | 100 | Pediatrics, Perinatology and Child Health; Medicine; Neurology | Medicine | 2,022 |
34,836,776 | Combined Quantification of [18]F-FDG and [68]Ga-DOTATATE PET/CT for Prognosis in High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms. | Academic radiology | Acad Radiol | 29 | 9 | 10.1016/j.acra.2021.10.004 | eng | 2,022 | 9 | null | 2,021 | 11 | 24 | [RATIONALE AND OBJECTIVES] High-grade gastroenteropancreatic neuroendocrine neoplasms (G3 GEP-NENs) are pathologically classified into well differentiated neuroendocrine tumors (G3 NETs) and poorly differentiated neuroendocrine carcinomas (G3 NECs). Using a novel parameter, we examined the prognostic value of [18]F-FDG... | (18)F-fluorodeoxyglucose; (68)Ga-DOTATATE; Gastroenteropancreatic neuroendocrine neoplasm; Positron emission tomography computed tomography; Prognostic factor | 1.064 | 113 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,022 |
34,836,756 | Feasibility, acceptability and sustainability of postpartum contraceptive implant provision by midwives in NSW public hospitals. | Women and birth : journal of the Australian College of Midwives | Women Birth | 35 | 5 | 10.1016/j.wombi.2021.11.002 | eng | 2,022 | 9 | null | 2,021 | 11 | 23 | [BACKGROUND] Repeat pregnancy in the first year after a birth is common. Many of these conceptions are unintended and may be prevented by providing access to contraception in the immediate postpartum period. Midwives in the hospital setting could potentially play a greater role in improving postnatal contraception info... | Contraceptive implant; Midwife; Postpartum contraception | 1.033 | 63 | Maternity and Midwifery; Medicine; Obstetrics and Gynecology | Medicine; Nursing | 2,022 |
34,836,534 | Digital analysis of external fixation area of proximal humerus fractures in elderly patients. | BMC musculoskeletal disorders | BMC Musculoskelet Disord | 22 | 1 | 10.1186/s12891-021-04826-0 | eng | 2,021 | 11 | 26 | 2,021 | 11 | 26 | [INTRODUCTION] The purpose is based on anatomical basis, combined with three-dimensional measurement, to guide the clinical repositioning of proximal humeral fractures, select the appropriate pin entry point and angle, and simulate surgery. [METHODS] 11 fresh cadaveric specimens were collected, the distance of the mark... | 3D model; Anatomic measurement; Elderly; Proximal humerus; Simulated screw placement | 0.669 | 131 | Orthopedics and Sports Medicine; Rheumatology | Medicine | 2,021 |
34,836,264 | A Machine Learning-Based Screening Test for Sarcopenic Dysphagia Using Image Recognition. | Nutrients | Nutrients | 13 | 11 | 10.3390/nu13114009 | eng | 2,021 | 11 | 10 | 2,021 | 11 | 10 | [BACKGROUND] Sarcopenic dysphagia, a swallowing disorder caused by sarcopenia, is prevalent in older patients and can cause malnutrition and aspiration pneumonia. This study aimed to develop a simple screening test using image recognition with a low risk of droplet transmission for sarcopenic dysphagia. [METHODS] Older... | dysphagia; image recognition; sarcopenia; screening | 1.287 | 243 | Food Science; Nutrition and Dietetics | Agricultural and Biological Sciences; Nursing | 2,021 |
34,836,202 | Fasting Interventions for Stress, Anxiety and Depressive Symptoms: A Systematic Review and Meta-Analysis. | Nutrients | Nutrients | 13 | 11 | 10.3390/nu13113947 | eng | 2,021 | 11 | 5 | 2,021 | 11 | 5 | [BACKGROUND] Fasting interventions have shown effectiveness in alleviating stress, anxiety and depressive symptoms. However, no quantitative analysis has been carried out thus far. The objective was to determine the effectiveness of fasting interventions on stress, anxiety and depression and if these interventions were... | antidepressant; anxiety; depression; fasting; mental health; obesity; physical health; public health; schizophrenia | 1.287 | 243 | Food Science; Nutrition and Dietetics | Agricultural and Biological Sciences; Nursing | 2,021 |
34,836,200 | Influence of Nutrition, Food and Diet-Related Interventions in the Workplace: A Meta-Analysis with Meta-Regression. | Nutrients | Nutrients | 13 | 11 | 10.3390/nu13113945 | eng | 2,021 | 11 | 4 | 2,021 | 11 | 4 | [OBJECTIVE] To review the scientific literature on the influence of verified nutrition, food and diet interventions on occupational health. [METHOD] This study involved a critical analysis of articles retrieved from MEDLINE (via PubMed), Embase, Cochrane Library, PsycINFO, Scopus, Web of Science, Latin American and Car... | diet; food; nutrition; obesity; occupational health; occupational health policy; overweight; working conditions; workplace | 1.287 | 243 | Food Science; Nutrition and Dietetics | Agricultural and Biological Sciences; Nursing | 2,021 |
34,832,568 | Plant Food Allergy Improvement after Grass Pollen Sublingual Immunotherapy: A Case Series. | Pathogens (Basel, Switzerland) | Pathogens | 10 | 11 | 10.3390/pathogens10111412 | eng | 2,021 | 10 | 30 | 2,021 | 10 | 30 | [BACKGROUND] Cross-reactivity between pollens and plant food has been widely described. Pollen extract subcutaneous immunotherapy in patients with pollens and plant food allergy has been shown to improve tolerance not only to inhalant allergens but also to reduce symptoms in patients with various food allergies. [METHO... | grass pollen allergy; plant food allergy; rhinitis; sublingual immunotherapy; tolerance | 0.901 | 82 | Immunology and Allergy; Immunology and Microbiology; Infectious Diseases; Microbiology; Molecular Biology | Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine | 2,021 |
34,827,416 | Effects of Physical Exercise on Cognition and Telomere Length in Healthy Older Women. | Brain sciences | Brain Sci | 11 | 11 | 10.3390/brainsci11111417 | eng | 2,021 | 10 | 27 | 2,021 | 10 | 27 | [BACKGROUND] Physical exercise is an effective measure for preventing the onset of cognitive decline and has a direct influence on the aging process. The purpose of this study was to assess the effect of a 6-month physical exercise program on cognition and telomere length in adults over 65 years of age. [METHOD] Sevent... | adults; ageing; cognition; exercise; telomerase | 0.727 | 78 | Neuroscience | Neuroscience | 2,021 |
34,827,076 | Gait Characteristics and Fatigue Profiles When Standing on Surfaces with Different Hardness: Gait Analysis and Machine Learning Algorithms. | Biology | Biology (Basel) | 10 | 11 | 10.3390/biology10111083 | eng | 2,021 | 10 | 22 | 2,021 | 10 | 22 | [BACKGROUND] Longtime standing may cause fatigue and discomfort in the lower extremities, leading to an increased risk of falls and related musculoskeletal diseases. Therefore, preventive interventions and fatigue detection are crucial. This study aims to explore whether anti-fatigue mats can improve gait parameters fo... | KNN classification algorithm; fatigue; floor mats; gait analysis; gender; long time standing | 0.903 | 91 | Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology | Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology | 2,021 |
34,826,174 | Patients with resolution of low-lying placenta and placenta previa remain at increased risk of postpartum hemorrhage. | Ultrasound in obstetrics gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology | Ultrasound Obstet Gynecol | 60 | 1 | 10.1002/uog.24825 | eng | 2,022 | 7 | null | 2,022 | 6 | 9 | [OBJECTIVE] To determine whether women who experience resolution of low placentation (low-lying placenta or placenta previa) are at increased risk of postpartum hemorrhage compared to those with normal placentation throughout pregnancy. [METHODS] This was a retrospective cohort study of women who delivered at Mount Sin... | low placentation; obstetric ultrasound; postpartum hemorrhage; resolved low-lying placenta; resolved placenta previa; risk factors; uterotonic medication | null | null | null | null | null |
34,826,172 | Validation of the Arabic translation of the caries impacts and experiences questionnaire for children. | International journal of paediatric dentistry | Int J Paediatr Dent | 32 | 5 | 10.1111/ipd.12944 | eng | 2,022 | 9 | null | 2,022 | 3 | 8 | [BACKGROUND] The recently developed Caries Impacts and Experiences Questionnaire for Children (CARIES-QC) is originally an English questionnaire targeting the assessment of caries-related quality of life from a child's point of view. [AIM] This study aimed to translate and adapt the CARIES-QC into the Arabic language a... | Arabic; dental caries; quality of life; reliability; validity | 0.945 | 81 | Dentistry | Dentistry | 2,022 |
34,826,109 | Upper-Body Post-activation Performance Enhancement for Athletic Performance: A Systematic Review with Meta-analysis and Recommendations for Future Research. | Sports medicine (Auckland, N.Z.) | Sports Med | 52 | 4 | 10.1007/s40279-021-01598-4 | eng | 2,022 | 4 | null | 2,021 | 11 | 26 | [BACKGROUND] Research on post-activation performance enhancement (PAPE) is dominated by lower-body conditioning activities/performance test complexes. Despite the contribution of the upper body to many sporting actions, no review on upper-body PAPE currently exists. [OBJECTIVES] The aim of this systematic review with m... | null | 3.292 | 247 | Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science | Health Professions; Medicine | 2,022 |
34,825,939 | Assessment of normal fetal cortical sulcus development. | Archives of gynecology and obstetrics | Arch Gynecol Obstet | 306 | 3 | 10.1007/s00404-021-06334-x | eng | 2,022 | 9 | null | 2,021 | 11 | 26 | [OBJECTIVE] The aim of our study was to investigate the normal cortical sulcus development in fetuses without central nervous system abnormality with transabdominal ultrasonography. [METHODS] Our study was planned as a cross-sectional study in our clinic between November 2011 and October 2012. The study group was selec... | Prenatal diagnosis; Sulcus; Ultrasonography | 0.727 | 90 | Medicine; Obstetrics and Gynecology | Medicine | 2,022 |
34,825,929 | Mechanisms of oxygenation responses to proning and recruitment in COVID-19 pneumonia. | Intensive care medicine | Intensive Care Med | 48 | 1 | 10.1007/s00134-021-06562-4 | eng | 2,022 | 1 | null | 2,021 | 11 | 26 | [PURPOSE] This study aimed at investigating the mechanisms underlying the oxygenation response to proning and recruitment maneuvers in coronavirus disease 2019 (COVID-19) pneumonia. [METHODS] Twenty-five patients with COVID-19 pneumonia, at variable times since admission (from 1 to 3 weeks), underwent computed tomograp... | ARDS; COVID-19; Lung recruitment; Mechanical ventilation; Prone position | 6.229 | 246 | Critical Care and Intensive Care Medicine | Medicine | 2,022 |
34,825,860 | Effects of Co-Solvents on Loading and Release Properties of Self- Assembled Di-Peptide Building Blocks, Towards Drug Delivery Applications. | Protein and peptide letters | Protein Pept Lett | 29 | 1 | 10.2174/0929866528666211126160432 | eng | 2,022 | null | null | null | null | null | [BACKGROUND] Due to their solid-like porous structure, molecular organogel and microcrystal structures have the capabilities of loading drug molecules, encapsulation, and extended release, all considered as essential properties in drug delivery applications. Phases of these structures, however, depend on the solvent us... | Nanomedicine; diphenylalanine; drug delivery; organogel; peptide; self-assembly | null | null | null | null | null |
34,825,635 | Erythrocyte-cancer Hybrid Membrane-camouflaged Mesoporous Silica Nanoparticles Loaded with Gboxin for Glioma-targeting Therapy. | Current pharmaceutical biotechnology | Curr Pharm Biotechnol | 23 | 6 | 10.2174/1389201022666210719164538 | eng | 2,022 | null | null | null | null | null | [OBJECTIVE] The purpose of this research is to formulate a biomimetic drug delivery system, which can selectively target glioblastoma (GBM) to deliver the antitumor agent, Gboxin, a novel Complex V inhibitor. Gboxin can specifically inhibit GBM cell growth but not normal cells. [METHODS] In the present study, we utiliz... | Glioblastoma (GBM); biomimetic nanoparticles; gboxin; homotypic targeting; hybrid membrane; mesoporous silica nanoparticles (MSNs) | null | null | null | null | null |
34,825,496 | Combining a β3 adrenergic receptor agonist with alpha-lipoic acid reduces inflammation in male mice with diet-induced obesity. | Obesity (Silver Spring, Md.) | Obesity (Silver Spring) | 30 | 1 | 10.1002/oby.23309 | eng | 2,022 | 1 | null | 2,021 | 11 | 25 | [OBJECTIVES] Beta-3 adrenergic receptors (β3-AR) stimulate lipolysis and thermogenesis in white and brown adipose tissue (WAT and BAT). Obesity increases oxidative stress and inflammation that attenuate AT β3-AR signaling. The objective of this study was to test the hypothesis that the combination of the β3-AR agonist ... | null | 1.826 | 234 | Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine; Nutrition and Dietetics | Biochemistry, Genetics and Molecular Biology; Medicine; Nursing | 2,022 |
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