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34,928,520
Changes in alcohol use by cannabis use status among adolescents and young adults in the United States: Emerging evidence for both substitution and complementarity.
Alcoholism, clinical and experimental research
Alcohol Clin Exp Res
45
12
10.1111/acer.14737
eng
2,021
12
null
2,021
12
20
[BACKGROUND] The majority of adolescents and young adults (AYA) who use cannabis also use alcohol. Although cannabis use is increasing in the United States (US), it is not known whether the increase contributes to either increased co-use of alcohol and cannabis (e.g., complementarity) or replacement of alcohol with can...
alcohol; cannabis; epidemiology; young adults; youth
null
null
null
null
null
34,928,448
Pediatric elbow arthroscopy: clinical outcomes and complications after long-term follow-up.
Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
J Orthop Traumatol
22
1
10.1186/s10195-021-00619-2
eng
2,021
12
20
2,021
12
20
[BACKGROUND] Elbow arthroscopy is becoming increasingly important for the treatment of a wide range of acute and chronic elbow pathologies. Even if elbow arthroscopy is technically demanding, in the pediatric population this minimally invasive technique is preferred by many surgeons for the treatment of pathologies suc...
Elbow arthroscopy; Osteochondritis dissecans; Pediatric; Posterior impingement; Posttraumatic stiffness
1.016
55
Medicine; Orthopedics and Sports Medicine; Surgery
Medicine
2,021
34,928,432
Out-of-pocket payments and catastrophic expenditures due to traffic injuries in Ouagadougou, Burkina Faso.
Health economics review
Health Econ Rev
11
1
10.1186/s13561-021-00344-w
eng
2,021
12
20
2,021
12
20
[OBJECTIVE] To estimate the out-of-pocket expenditures linked to Road Traffic Injuries in Ouagadougou, Burkina Faso, as well as the prevalence of catastrophic expenditures among those out-of-pocket payments, and to identify the socio-economic determinants of catastrophic expenditures due to Road Traffic Injuries. [METH...
Accidents injuries; Catastrophic expenditures; Health economics; Health equity; Health financing; Health insurance; Noncommunicable disease; Road traffic injuries; Trauma care
0.535
41
Health Policy
Medicine
2,021
34,928,394
Are Farmers Willing to Substitute Tobacco Cultivation? Evidence From Lichuan City, China.
Nicotine tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Nicotine Tob Res
24
6
10.1093/ntr/ntab264
eng
2,022
4
28
null
null
null
[INTRODUCTION] Tobacco crop substitution is a critical element in implementing comprehensive tobacco control policies. Understanding tobacco farmers' willingness or preferences is imperative to implement policies on tobacco crop substitution. This article assesses tobacco farmers' individual willingness to substitute t...
null
null
null
null
null
null
34,927,696
Applicability of a General Analytical Approach for Detection of Genetically Modified Organisms: Collaborative Trial.
Journal of AOAC International
J AOAC Int
105
2
10.1093/jaoacint/qsab154
eng
2,022
3
15
null
null
null
[BACKGROUND] With the commercialization of genetically modified organisms (GMOs) in the market, laboratories have undergone a significantly increased workload. A universal analytical approach was designed to achieve cost-efficient and high-throughput GMOs screening with high specificity and accuracy. The approach provi...
null
0.358
106
Agronomy and Crop Science; Analytical Chemistry; Environmental Chemistry; Food Science; Pharmacology
Agricultural and Biological Sciences; Chemistry; Environmental Science; Pharmacology, Toxicology and Pharmaceutics
2,022
34,927,593
The Impact of Patient Characteristics on Their Attitudes Toward an Online Patient Portal for Communicating Laboratory Test Results: Real-World Study.
JMIR formative research
JMIR Form Res
5
12
10.2196/25498
eng
2,021
12
17
2,021
12
17
[BACKGROUND] Patient portals are promising tools to increase patient involvement and allow them to manage their health. To optimally facilitate patients, laboratory test results should be explained in easy language. Patient characteristics affect the usage of portals and the user satisfaction. However, limited research...
age; chronic disease; eHealth impact questionnaire; education; gender; laboratory test results; patient characteristics; patient portal; self-efficacy; usability
0.49
31
Health Informatics; Medicine
Medicine
2,021
34,927,371
Development and validation of a prediction model using molecular marker for long-term survival in unresectable stage III non-small cell lung cancer treated with chemoradiotherapy.
Thoracic cancer
Thorac Cancer
13
3
10.1111/1759-7714.14218
eng
2,022
2
null
2,021
12
19
[BACKGROUND] This study aimed to establish a predictive nomogram integrating epidermal growth factor receptor (EGFR) mutation status for 3- and 5-year overall survival (OS) in unresectable/inoperable stage III non-small cell lung cancer (NSCLC) treated with definitive chemoradiotherapy. [METHODS] A total of 533 stage I...
chemoradiotherapy; nomogram; non-small cell lung cancer; survival
0.73
55
Medicine; Oncology; Pulmonary and Respiratory Medicine
Medicine
2,022
34,927,323
Hyponatremia an indicator of complicated appendicitis in children: Starship experience.
ANZ journal of surgery
ANZ J Surg
92
4
10.1111/ans.17425
eng
2,022
4
null
2,021
12
19
[BACKGROUND] Timely preoperative recognition of children with complicated appendicitis allows for planning and effective management. The aim of this study was to evaluate hyponatremia, an objective biochemical marker, as a predictor of complicated appendicitis. [METHODS] A retrospective review of 1283 paediatric patien...
appendicitis; hyponatremia; paediatrics; retrospective studies; sodium
0.406
89
Surgery; Medicine
Medicine
2,022
34,927,280
Ultrasonic Characterization of Primary Squamous Cell Carcinoma of the Thyroid.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
J Ultrasound Med
41
9
10.1002/jum.15918
eng
2,022
9
null
2,021
12
20
[OBJECTIVES] To identify the ultrasonographic characteristics of primary squamous cell carcinoma of the thyroid (PSCCT), and to assess the value of the 2015 American Thyroid Association (ATA) guideline and 2017 American College of Radiology (ACR) Thyroid Imaging, Reporting and Data System (TI-RADS) in the evaluation of...
ATA; TI-RADS; primary squamous cell carcinoma; thyroid; ultrasound
0.616
108
Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine
2,022
34,927,217
Geographic Variations in Diagnosis and Treatment of Ankylosing Spondylitis in the United States: A Real-World Study.
Rheumatology and therapy
Rheumatol Ther
9
2
10.1007/s40744-021-00406-9
eng
2,022
4
null
2,021
12
19
[INTRODUCTION] Diagnosis difficulties are common for ankylosing spondylitis (AS) patients, leading to inadequate and inconsistent treatment. We evaluated the national and geographic variability in disease diagnosis and treatment in the United States. [METHODS] This retrospective, cross-sectional analysis utilized the I...
Ankylosing spondylitis; Biologic disease-modifying antirheumatic drugs; Diagnosis; Epidemiology; Opioids; Real world; States; Targeted immunomodulator; United States
1.242
40
Rheumatology; Immunology and Allergy
Medicine
2,022
34,926,777
"Post Mastectomy Pain Syndrome: A Systematic Review of Prevention Modalities".
JPRAS open
JPRAS Open
31
null
10.1016/j.jpra.2021.10.009
eng
2,022
3
null
2,021
10
30
[BACKGROUND] Post-mastectomy pain syndrome (PMPS) is a surgical complication of breast surgery characterized by chronic neuropathic pain. The development of PMPS is multifactorial and research on its prevention is limited. The objective of this systematic review is to synthesize the existing evidence on interventions f...
neuropathic pain; post-mastectomy pain syndrome; prevention; systematic review
null
null
null
null
null
34,926,674
Long-term and short-term prognostic value of the prognostic nutritional index in cancer: a narrative review.
Annals of translational medicine
Ann Transl Med
9
21
10.21037/atm-21-4528
eng
2,021
11
null
null
null
null
[OBJECTIVE] To perform a narrative review of the prognostic value of prognostic nutritional index (PNI) in cancers. [BACKGROUND] Prognostic estimation greatly determines the treatment approach in various cancers. The PNI, calculated using the serum albumin level and total lymphocyte count, is a useful indicator to asse...
Prognostic nutrition index (PNI); cancer; prognosis; review
null
null
null
null
null
34,926,671
The monocyte to high-density lipoprotein cholesterol ratio and outcomes in type 2 diabetes mellitus patients with non-ST-segment elevation acute coronary syndrome.
Annals of translational medicine
Ann Transl Med
9
21
10.21037/atm-21-4876
eng
2,021
11
null
null
null
null
[BACKGROUND] The monocyte to high-density lipoprotein cholesterol ratio (MHR) has been demonstrated as a new marker of inflammation. However, at present, the prognostic value of MHR in type 2 diabetes mellitus (T2DM) accompanied with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) undergoing percutaneous co...
outcomes; type 2 diabetes mellitus (T2DM)
null
null
null
null
null
34,926,312
Bibliometric Analysis of the Top-Cited Publications and Research Trends for Stereotactic Body Radiotherapy.
Frontiers in oncology
Front Oncol
11
null
10.3389/fonc.2021.795568
eng
2,021
null
null
2,021
12
3
[OBJECTIVE] This study aims to analyze the 100 most cited papers and research trends on stereotactic body radiotherapy (SBRT). [METHODS] We used Web of Science to identify the 100 most frequently cited papers on SBRT on September 29, 2021 and extracted the following data: publication year, source title, country/region,...
bibliometric analysis; immunotherapy; lung cancer; oligometastases; stereotactic ablative radiotherapy (SABR); stereotactic body radiotherapy (SBRT)
1.291
156
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,926,267
SEPT6_TRIM33 Gene Fusion and Mutated TP53 Pathway Associate With Unfavorable Prognosis in Patients With B-Cell Lymphomas.
Frontiers in oncology
Front Oncol
11
null
10.3389/fonc.2021.765544
eng
2,021
null
null
2,021
12
1
[BACKGROUND] Mounting studies have sought to identify novel mutation biomarkers having diagnostic and prognostic potentials. Nevertheless, the understanding of the mutated pathways related to development and prognosis of B-cell lymphoma is still lacking. We aimed to comprehensively analyze the mutation alterations in g...
B-cell lymphoma; Hippo pathway; TP53 signaling pathway; gene fusion; mutated pathway; prognosis
1.291
156
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,925,864
Development and Preliminary Psychometric Testing of an Adult Chronic Kidney Disease Self-Management (CKD-SM) Questionnaire.
Canadian journal of kidney health and disease
Can J Kidney Health Dis
8
null
10.1177/20543581211063981
eng
2,021
null
null
2,021
12
12
[BACKGROUND] Self-management focused interventions to slow chronic kidney disease (CKD) progression are increasingly common. However, valid self-report instruments to evaluate the effectiveness of self-management interventions in CKD are limited. [OBJECTIVE] We sought to develop and conduct preliminary psychometric tes...
chronic kidney disease; patient-reported outcomes; pre-dialysis; questionnaire development; self-management
0.686
37
Nephrology
Medicine
2,021
34,925,746
One-stop shop for variceal surveillance: integration of unsedated ultrathin endoscopy into the routine clinic visit.
Frontline gastroenterology
Frontline Gastroenterol
12
7
10.1136/flgastro-2020-101680
eng
2,021
null
null
2,021
1
12
[BACKGROUND] The endoscopic appearance of oesophageal varices determines the need for prophylaxis. However, as the point prevalence of varices is low (25%), the majority of surveillance endoscopies are unnecessary and costly. Narrow diameter, ultrathin (UT) endoscopes are more tolerable than conventional upper gastroin...
cirrhosis; clinical decision making; endoscopy; health economics; oesophageal varices
null
null
null
null
null
34,925,735
Diagnosis and Treatment Rules of Chronic Kidney Disease and Nursing Intervention Models of Related Mental Diseases Using Electronic Medical Records and Data Mining.
Journal of healthcare engineering
J Healthc Eng
2021
null
10.1155/2021/5187837
eng
2,021
null
null
2,021
12
10
[OBJECTIVE] On the basis of electronic medical records, the data mining technology was adopted to explore the law of chronic kidney disease (CKD) and the intervention mode of mental health of patients. [METHODS] Based on the electronic medical records, the corresponding data extraction, database establishment, and data...
null
0.684
69
Biomedical Engineering; Biotechnology; Health Informatics; Surgery
Biochemistry, Genetics and Molecular Biology; Engineering; Medicine
2,021
34,924,424
Impact of COVID-19 on rehabilitation experiences of physiotherapists.
Work (Reading, Mass.)
Work
71
1
10.3233/WOR-210658
eng
2,022
null
null
null
null
null
[BACKGROUND] As the COVID-19 pandemic progressed, pressures on almost all health sectors in many countries increased, and physiotherapy interventions were canceled for various reasons. [OBJECTIVES] The aim of this study was to determine the status of physiotherapists who interrupted their services due to the pandemic a...
COVID-19; Coronavirus; health professionals; preventive measures; telehealth
null
null
null
null
null
34,924,413
Reaching in sitting: The effect of seat design and body manipulations.
Work (Reading, Mass.)
Work
71
1
10.3233/WOR-205114
eng
2,022
null
null
null
null
null
[BACKGROUND] Sitting is a common and familiar position used daily as a platform for many motor activities in the workplace, at school, or at home. [OBJECTIVE] To investigate how difference in the chair design and selected sitting manipulations contribute to reach distance in sitting. [METHODS] Ten healthy subjects were...
Sitting; arm support; footrest; inclined seat; leg support; legs crossed; maximum reach
null
null
null
null
null
34,924,352
Lower levels of low-density lipoprotein cholesterol are associated with a lower prevalence of thin-cap fibroatheroma in statin-treated patients with coronary artery disease.
Journal of clinical lipidology
J Clin Lipidol
16
1
10.1016/j.jacl.2021.11.012
eng
2,022
null
null
2,021
12
4
[BACKGROUND] Reducing low-density lipoprotein cholesterol (LDL-C) levels with statins slows the progression of atherosclerotic plaques and reduces cardiovascular events. The 2019 European Society of Cardiology/European Atherosclerosis Society guidelines recommend absolute LDL-C treatment targets of 100 mg/dL, 70 mg/dL ...
Lipid-lowering therapy; Optical coherence tomography; Percutaneous coronary intervention; Secondary prevention; Vulnerable plaque
1.256
79
Cardiology and Cardiovascular Medicine; Endocrinology, Diabetes and Metabolism; Internal Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
34,924,111
Correlates and predictors of re-incarceration among Turkish adolescent male offenders: A single-center, cross-sectional study.
International journal of law and psychiatry
Int J Law Psychiatry
80
null
10.1016/j.ijlp.2021.101726
eng
2,022
null
null
null
null
null
[BACKGROUND] Adolescents involved in the legal system are known to be under elevated risk for repeat offending. There may be many reasons for recidivism. Specifically, we aim to investigate the clinical, socio-demographic, and familial factors and psychopathology among adolescents in a penal institution and to determin...
Adolescent; Inmate; Prison; Psychopathology; Re-incarceration
0.754
80
Law; Pathology and Forensic Medicine; Psychiatry and Mental Health
Medicine; Social Sciences
2,022
34,924,086
Prediction of extubation failure in the paediatric cardiac ICU using machine learning and high-frequency physiologic data.
Cardiology in the young
Cardiol Young
32
10
10.1017/S1047951121004959
eng
2,022
10
null
2,021
12
20
[BACKGROUND] Cardiac intensivists frequently assess patient readiness to wean off mechanical ventilation with an extubation readiness trial despite it being no more effective than clinician judgement alone. We evaluated the utility of high-frequency physiologic data and machine learning for improving the prediction of ...
Airway extubation; artificial respiration; clinical decision-making; machine learning; quality of healthcare
0.387
68
Cardiology and Cardiovascular Medicine; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,022
34,923,964
Aging through the time of COVID-19: a survey of self-reported healthcare access.
BMC health services research
BMC Health Serv Res
21
1
10.1186/s12913-021-07353-9
eng
2,021
12
19
2,021
12
19
[BACKGROUND] Chronic conditions are common and require ongoing continuous management and preventive measures. The COVID-19 pandemic may have affected the management of chronic conditions by delaying care. We sought to understand the impact of personal characteristics (i.e., age) and healthcare factors (i.e., access to ...
Barriers; COVID-19; Chronic conditions; Healthcare access; Older adults; Pandemic
0.997
157
Health Policy
Medicine
2,021
34,923,613
Efficacy of platelet-rich fibrin in promoting the healing of extraction sockets: a systematic review.
International journal of implant dentistry
Int J Implant Dent
7
1
10.1186/s40729-021-00393-0
eng
2,021
12
19
2,021
12
19
[PURPOSE] To address the focused question: in patients with freshly extracted teeth, what is the efficacy of platelet-rich fibrin (PRF) in the prevention of pain and the regeneration of soft tissue and bone compared to the respective control without PRF treatment? [METHODS] After an electronic data search in PubMed dat...
PRF; Pain management; Platelet-rich fibrin; Ridge preservation; Socket healing; Socket preservation; Soft tissue healing
null
4
Medicine
Medicine
2,022
34,923,564
Emergence agitation in paediatric day case surgery: A randomised, single-blinded study comparing narcotrend and heart rate variability with standard monitoring.
European journal of anaesthesiology
Eur J Anaesthesiol
39
3
10.1097/EJA.0000000000001649
eng
2,022
3
1
null
null
null
[BACKGROUND] Postoperative emergence agitation remains a significant challenge in paediatric anaesthesia. Although short-lived, it may cause harm to the patient and negative experiences for all. Differentiating agitation, delirium and pain is difficult. Electroencephalography allows precise titration of anaesthetic dep...
null
0.846
94
Anesthesiology and Pain Medicine
Medicine
2,022
34,923,510
PREDICTED PROTEIN STRUCTURE VARIATIONS INDICATE THE CLINICAL PRESENTATION OF CYP4V2-RELATED BIETTI CRYSTALLINE DYSTROPHY.
Retina (Philadelphia, Pa.)
Retina
42
4
10.1097/IAE.0000000000003381
eng
2,022
4
1
null
null
null
[PURPOSE] To investigate the relationship between different CYP4V2 disease-causing variants and disease severity in Bietti crystalline dystrophy (BCD). [METHODS] Twenty-one subjects from 19 unrelated families with a clinical diagnosis of BCD were enrolled. A novel severity prediction score for BCD based on the predicte...
null
1.206
149
Medicine; Ophthalmology
Medicine
2,022
34,923,503
Hybrid Therapy Versus Total En Bloc Spondyectomy in the Treatment of Solitary Radioresistant Spinal Metastases: A Single-center, Retrospective Study.
Clinical spine surgery
Clin Spine Surg
35
5
10.1097/BSD.0000000000001280
eng
2,022
6
1
2,021
12
20
[STUDY DESIGN] This was a retrospective study. [OBJECTIVE] To compare the treatment efficacy of hybrid therapy (HT) with that of total en bloc spondylectomy (TES) in patients with solitary radioresistant high-grade epidural spinal cord compression (ESCC) spinal metastases. [SUMMARY OF BACKGROUND DATA] Both HT and TES c...
null
0.682
45
Neurology; Orthopedics and Sports Medicine; Surgery
Medicine
2,022
34,923,478
PERINATAL ASPECTS OF INTRAUTERINE INFECTIONS.
Wiadomosci lekarskie (Warsaw, Poland : 1960)
Wiad Lek
74
10 cz 2
null
eng
2,021
null
null
null
null
null
[OBJECTIVE] The aim: To analyze Ukrainian and foreign literature data on the consequences of perinatal infection and the peculiarities of their manifestation. [PATIENTS AND METHODS] Materials and methods: Literature sources on the peculiarities of the course of infection that occur in the perinatal period and are a thr...
congenital infections; fetus; newborn
null
null
null
null
null
34,923,358
Assessment of improvement in anxiety severity for children with autism spectrum disorder: The matched correspondence analysis approach.
Journal of psychiatric research
J Psychiatr Res
145
null
10.1016/j.jpsychires.2021.12.004
eng
2,021
12
15
2,021
12
15
[INTRODUCTION] Clinical trials typically involve random assignment to treatment conditions. However, random assignment does not guarantee a lack of systematic variation in the outcomes, and application of covariation methods for multiple dependent measures requires complicated assumptions that are often not met. [METHO...
Autism spectrum disorder (ASD); Cognitive behavioral therapy (CBT); Matched correspondence analysis; Treatment as usual (TAU)
1.56
172
Biological Psychiatry; Psychiatry and Mental Health
Medicine; Neuroscience
2,021
34,923,153
No room for pain: A prospective study showing effective and nearly pain-free treatment of actinic keratosis with simulated daylight photodynamic therapy (SDL-PDT) using the IndoorLux® System in combination with BF-200 ALA (Ameluz®).
Photodiagnosis and photodynamic therapy
Photodiagnosis Photodyn Ther
37
null
10.1016/j.pdpdt.2021.102692
eng
2,022
3
null
2,021
12
17
[BACKGROUND] Photodynamic therapy (PDT) with natural daylight is effective and less painful than conventional PDT when treating actinic keratosis (AK), however its weather dependency is restrictive. This prospective open-label observational single-arm study examined efficacy and safety of simulated daylight (SDL)-PDT u...
5-aminolevulinic acid gel; Actinic keratosis; Simulated daylight photodynamic therapy
0.633
73
Biophysics; Dermatology; Pharmacology; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,923,067
Analysis of spin in vascular surgery randomized controlled trials with nonsignificant outcomes.
Journal of vascular surgery
J Vasc Surg
75
3
10.1016/j.jvs.2021.09.051
eng
2,022
3
null
2,021
12
16
[OBJECTIVE] Spin is the manipulation of language that distorts the interpretation of objective findings. The purpose of this study is to describe the characteristics of spin found in statistically nonsignificant randomized controlled trials (RCT) comparing carotid endarterectomy with carotid artery stenting for carotid...
Aneurysm; Carotid; Trials
2.027
225
Cardiology and Cardiovascular Medicine; Surgery
Medicine
2,022
34,922,612
Solvothermal synthesis of pure and Sn-doped Bi2S3 and the evaluation of their photocatalytic activity on the degradation of methylene blue.
BMC chemistry
BMC Chem
15
1
10.1186/s13065-021-00792-9
eng
2,021
12
18
2,021
12
18
[BACKGROUND] A large volume of dye molecules finds its way into the environment, accumulates in water bodies, and makes the aquatic system unsafe to human health. Due to the complex nature of these dye materials, most of the conventional techniques are not effective for their removal. Semiconductor photocatalysis has e...
Bismuth sulphide; Methylene blue; Nanorods; Photocatalysis; Sn-doped
null
null
null
null
null
34,922,582
Colonization of fecal microbiota from patients with neonatal necrotizing enterocolitis exacerbates intestinal injury in germfree mice subjected to necrotizing enterocolitis-induction protocol via alterations in butyrate and regulatory T cells.
Journal of translational medicine
J Transl Med
19
1
10.1186/s12967-021-03109-5
eng
2,021
12
18
2,021
12
18
[BACKGROUND] Necrotizing enterocolitis (NEC) remains a life-threatening disease in neonates. Numerous studies have shown a correlation between the intestinal microbiota and NEC, but the causal link remains unclear. This study aimed to demonstrate the causal role of gut microbiota in NEC and explore potential mechanisms...
Butyric acid; Fecal microbiota transplantation; Germ free; Gut microbiota; Necrotizing enterocolitis
1.57
153
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,922,479
Does time-to-surgery affect mortality in patients with acute osteoporotic vertebral compression fractures?
BMC geriatrics
BMC Geriatr
21
1
10.1186/s12877-021-02682-0
eng
2,021
12
18
2,021
12
18
[INTRODUCTION] Osteoporotic vertebral compression fractures (VCFs) are common. An increase in mortality associated with osteoporotic VCFs has been well documented. The purpose of this study was to assess the impact of time to surgery on 1-year survival in patients with osteoporotic vertebral compression fractures. [MET...
Complications; Fracture; Geriatric; Mortality; Osteoporosis; Vertebral compression fracture
1.153
112
Geriatrics and Gerontology
Medicine
2,021
34,922,224
The effects of the antecedent use of inhaled steroid on the clinical course of COVID-19: A retrospective study of asthmatic patients.
Journal of infection and public health
J Infect Public Health
15
1
10.1016/j.jiph.2021.12.003
eng
2,022
1
null
2,021
12
8
[BACKGROUND] There is conflicting evidence regarding the effect of asthma and its different therapeutic options on COVID-19 severity and the clinical outcomes. [AIM] This study aimed to investigate the relationship between using inhaled corticosteroids (ICS) by asthmatic patients and the severity of COVID-19. [MATERIAL...
Asthma; COVID-19; Inhaled corticosteroids; Viral infection
1.183
73
Infectious Diseases; Medicine; Public Health, Environmental and Occupational Health
Medicine
2,022
34,922,119
Imaging features to distinguish AQP4-positive NMOSD and MS at disease onset: A retrospective analysis in a single-center cohort.
European journal of radiology
Eur J Radiol
146
null
10.1016/j.ejrad.2021.110063
eng
2,022
1
null
2,021
11
23
[PURPOSE] To compare the diagnostic performance of imaging criteria that differentiate AQP4[+] Neuromyelitis Optica Spectrum Disorders (NMOSD) and Multiple Sclerosis (MS) at disease onset (DO) and follow-up (FU). [METHODS] We retrospectively analyzed MRI scans at DO (defined as the first 60 days of patient-reported sym...
AQP4+ neuromyelitis optica spectrum disorders; Diagnostic criteria; MRI; Multiple sclerosis; Real-life
0.939
139
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
34,921,934
Clinical Decision Support for Symptom Management in Lung Cancer Patients: A Group RCT.
Journal of pain and symptom management
J Pain Symptom Manage
63
4
10.1016/j.jpainsymman.2021.12.006
eng
2,022
4
null
2,021
12
16
[CONTEXT] Clinical guidelines are available to enhance symptom management during cancer treatment but often are not used in the practice setting. Clinical decision support can facilitate the implementation and adherence to clinical guidelines. and improve the quality of cancer care. [OBJECTIVES] Clinical decision suppo...
Symptom management; anxiety; clinical decision support; depression; dyspnea; fatigue health-related quality of life; nonsmall cell lung cancer; pain; patient-reported outcomes; symptom assessment
1.306
171
Anesthesiology and Pain Medicine; Neurology; Nursing
Medicine; Nursing
2,022
34,921,311
Exploring temporal trends and risk factors for resistance in Escherichia coli-causing bacteraemia in England between 2013 and 2018: an ecological study.
The Journal of antimicrobial chemotherapy
J Antimicrob Chemother
77
3
10.1093/jac/dkab440
eng
2,022
2
23
null
null
null
[BACKGROUND] Escherichia coli are Gram-negative bacteria associated with an increasing burden of antimicrobial resistance (AMR) in England. [OBJECTIVES] To create a comprehensive epidemiological picture of E. coli bacteraemia resistance trends and risk factors in England by linking national microbiology data sources an...
null
1.382
229
Infectious Diseases; Microbiology; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
34,921,035
TNF-α and HMGB1: New Biomarkers of Acute Pulmonary Embolism.
Annals of clinical and laboratory science
Ann Clin Lab Sci
51
6
null
eng
2,021
11
null
2,021
12
17
[OBJECTIVE] Inflammatory mediators have been implicated in the pathophysiology of acute pulmonary embolism (PE). However, the role of inflammatory mediator activation in the development of pulmonary embolism remains elusive. Here, we determined the reliability of the plasma levels of inflammatory markers tumor necrosis...
Pulmonary embolism; high mobility histone 1; inflammation; tumor necrosis factor-alpha
null
null
null
null
null
34,920,877
The role of prehospital ultrasound in reducing time to definitive care in abdominal trauma patients with moderate to severe liver and spleen injuries.
Injury
Injury
53
5
10.1016/j.injury.2021.12.008
eng
2,022
5
null
2,021
12
8
[BACKGROUND] The role of prehospital focused assessment sonography for trauma (FAST) is still under debate and no definitive recommendations are available in actual guidelines, moreover, the availability of ultrasound machines in emergency medical services (EMS) is still inhomogeneous. On the other hand, time to defini...
Injuries, abdominal; Trauma centres; emergency surgery; haemorrhagic shock
0.698
151
Surgery; Emergency Medicine; Orthopedics and Sports Medicine
Medicine
2,022
34,920,435
Complete posterior cranial vault distraction osteogenesis to correct Chiari malformation type I associated with craniosynostosis.
Journal of neurosurgery. Pediatrics
J Neurosurg Pediatr
29
3
10.3171/2021.10.PEDS21443
eng
2,022
3
1
2,021
12
17
[OBJECTIVE] Posterior vault distraction osteogenesis (PVDO) is an effective tool to increase intracranial volume and expand the posterior cranial fossa. During PVDO, the authors extended osteotomy posterior to the foramen magnum to fully expand the posterior cranial fossa. The aim of this study was to investigate the e...
Arnold-Chiari malformation; craniofacial; distraction; osteogenesis; oxycephaly; sagittal synostosis
null
null
null
null
null
34,920,340
Risk of mortality and second malignancies in primary myelofibrosis before and after ruxolitinib approval.
Leukemia research
Leuk Res
112
null
10.1016/j.leukres.2021.106770
eng
2,022
1
null
2,021
12
9
[BACKGROUND] Primary myelofibrosis (PMF) is associated with morbidity and mortality. Ruxolitinib gained US FDA approval for treatment of intermediate/high-risk PMF in November 2011. We evaluated differences in survival and second primary malignancy (SPM) incidence among US PMF patients in the years before and after rux...
Leukemia transformation; Mortality; Primary myelofibrosis; Ruxolitinib; Second primary neoplasms
0.673
98
Hematology; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,920,318
Spontaneous enteroscrotal fistula following an incarcerated inguinal hernia in a neonate: Case report and literature review.
International journal of surgery case reports
Int J Surg Case Rep
90
null
10.1016/j.ijscr.2021.106656
eng
2,022
1
null
2,021
12
4
[INTRODUCTION] In Africa, frequent delays in seeking medical attention due to cultural considerations and lack of financial support could explain some particular clinical presentations. An enteroscrotal fistula following an incarcerated inguinal hernia is a rare condition in neonates. [PRESENTATION OF CASE] A 21-day-ol...
Enteroscrotal; Fistula; Hernia; Inguinal; Literature; Neonate
0.193
31
Surgery
Medicine
2,022
34,920,242
Afatinib After Progression on Osimertinib in EGFR-Mutated Non-Small Cell Lung Cancer.
Cancer treatment and research communications
Cancer Treat Res Commun
30
null
10.1016/j.ctarc.2021.100497
eng
2,022
null
null
2,021
12
3
[INTRODUCTION] After the development of acquired resistance to osimertinib, the standard-of-care treatment for advanced EGFR-mutated NSCLC is chemotherapy. Whether afatinib, a pan-ErbB family tyrosine kinase inhibitor, is active after progression on osimertinib is unknown. [METHODS] We conducted a single-institution re...
EGFR TKI; EGFR mutation; afatinib; cetuximab; osimertinib
0.674
29
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
34,920,113
Minimal important changes and differences were estimated for Oxford hip and knee scores following primary and revision arthroplasty.
Journal of clinical epidemiology
J Clin Epidemiol
143
null
10.1016/j.jclinepi.2021.12.016
eng
2,022
3
null
2,021
12
15
[OBJECTIVES] To create estimates for clinically meaningful changes and differences in pain and joint function for the Oxford Hip and Knee Scores (OHS/OKS) in primary and revision joint replacement. [STUDY DESIGN AND SETTING] 694,487 primary and revision joint replacement procedures were analyzed from the NHS PROMs data...
Patient-reported outcome measures; Re-operation; Revision; Total hip replacement; Total knee replacement
3.362
262
Epidemiology
Medicine
2,022
34,919,739
Accuracy of Xpert MTB/RIF assay for the diagnosis of tuberculous pleural effusion.
Journal of clinical laboratory analysis
J Clin Lab Anal
36
1
10.1002/jcla.24185
eng
2,022
1
null
2,021
12
17
[BACKGROUND] Tuberculosis poses a severe threat to human health. At present, compared with the traditional diagnostic methods for tuberculosis pleural effusion, such as Löwenstein-Jensen culture, pleural biopsy, and Ziehl-Neelsen smear microscopy, Xpert MTB/RIF was regarded as an emerging technology for its efficiency....
Xpert MTB/RIF; diagnostic; mycobacterium tuberculosis; pleural effusion; tuberculosis
0.594
67
Medical Laboratory Technology; Biochemistry; Clinical Biochemistry; Public Health, Environmental and Occupational Health; Hematology; Immunology and Allergy; Microbiology
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine
2,022
34,919,730
In Vitro Biocompatibility of CPP-ACP and Fluoride-containing Desensitizers on Human Gingival Cells.
Operative dentistry
Oper Dent
46
6
10.2341/20-245-L
eng
2,021
11
1
null
null
null
[OBJECTIVES] To analyze the biocompatibility of different desensitizers containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and fluoride in their composition: MI Varnish (MV), Clinpro White Varnish (3M Oral Care), Profluorid Varnish (VOCO), Duraphat (Colgate) and Embrace Varnish (Pulpdent) on human g...
null
0.702
96
Dentistry; Medicine
Dentistry; Medicine
2,021
34,919,335
Which factors influence the prevalence of institution-acquired falls? Results from an international, multi-center, cross-sectional survey.
Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing
J Nurs Scholarsh
54
4
10.1111/jnu.12758
eng
2,022
7
null
2,021
12
17
[PURPOSE] Falls are a highly prevalent problem in hospitals and nursing homes with serious negative consequences such as injuries, increased care dependency, or even death. The aim of this study was to provide a comprehensive insight into institution-acquired fall (IAF) prevalence and risk factors for IAF in a large sa...
accidental falls; hospital; institutional fall; nursing home; prevalence; risk factors
0.982
98
Nursing
Nursing
2,022
34,919,246
Curcumin protects against testis-specific side effects of irinotecan.
European review for medical and pharmacological sciences
Eur Rev Med Pharmacol Sci
25
23
10.26355/eurrev_202112_27441
eng
2,021
12
null
null
null
null
[OBJECTIVE] Irinotecan (IR/CPT-11) is a semisynthetic, water-soluble derivative of the alkaloid camptothecin. It is a topoisomerase I group antineoplastic drug commonly used for the treatment of many cancer types, although it has side effects in tissues such as the testis. Curcumin (CRC) is a polyphenol compound produc...
null
null
null
null
null
null
34,919,171
Investigation of Physical Properties of Disodium Etidronate Tetrahydrate and Application of Phosphorus K-Edge X-Ray Absorption Near-Edge Structure Spectroscopy.
Pharmaceutical research
Pharm Res
38
12
10.1007/s11095-021-03151-4
eng
2,021
12
null
2,021
12
17
[PURPOSE] Disodium etidronate is a bisphosphonate, compounds that are widely used in the treatment of bone disorders such as osteoporosis and Paget's disease. We investigated the physical properties of disodium etidronate tetrahydrate crystal, form I. [METHODS] We used X-ray powder diffraction (XRPD), thermal analysis,...
X-ray absorption near-edge structure spectroscopy; bisphosphonates; crystal structure; etidronate; physical properties
0.658
235
Biotechnology; Organic Chemistry; Pharmaceutical Science; Pharmacology; Pharmacology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,021
34,918,488
Differential diagnosis of lung cancer and benign lung lesion using salivary metabolites: A preliminary study.
Thoracic cancer
Thorac Cancer
13
3
10.1111/1759-7714.14282
eng
2,022
2
null
2,021
12
16
[BACKGROUND] Saliva is often used as a biomarker for the diagnosis of some oral and systematic diseases, owing to the non-invasive attribute of the fluid. In this study, we aimed to identify salivary biomarkers for distinguishing lung cancer (LC) from benign lung lesion (BLL). [MATERIALS AND METHODS] Unstimulated saliv...
benign lung lesion; lung cancer; metabolites; saliva
0.73
55
Medicine; Oncology; Pulmonary and Respiratory Medicine
Medicine
2,022
34,918,365
Dogliotti and Phillips classifications are unsuitable for grading the histopathological findings of exogenous ochronosis.
Journal of cutaneous pathology
J Cutan Pathol
49
5
10.1111/cup.14189
eng
2,022
5
null
2,021
12
26
[BACKGROUND] Cutaneous exogenous ochronosis (EO) is frequently graded and staged according to the Dogliotti or Phillips classification system, both in research studies and in clinical practice. There are no data to support the use of these systems in either of these settings. These systems additionally purport that the...
cosmetics; dermatology; granulomas; ochronosis; pathology
0.574
89
Dermatology; Histology; Pathology and Forensic Medicine
Medicine
2,022
34,918,348
Glymphatic dysfunction in isolated REM sleep behavior disorder.
Acta neurologica Scandinavica
Acta Neurol Scand
145
4
10.1111/ane.13573
eng
2,022
4
null
2,021
12
16
[OBJECTIVES] This study aimed to evaluate glymphatic-system function in patients with isolated rapid eye movement sleep behavior disorder (iRBD) in comparison with healthy controls by using diffusion tensor imaging (DTI) along the perivascular space (DTI-ALPS) method. We hypothesized that patients with iRBD may show gl...
REM sleep; diffusion tensor imaging; glymphatic system
0.865
114
Medicine; Neurology; Neurology
Medicine; Neuroscience
2,022
34,918,167
Drug Resistance in Children with Central Nervous System Tuberculosis from a Tertiary Care Center in Mumbai.
Journal of tropical pediatrics
J Trop Pediatr
67
6
10.1093/tropej/fmab098
eng
2,021
12
8
null
null
null
[INTRODUCTION] Central Nervous System tuberculosis (CNS-TB) is the most lethal form of extra-pulmonary TB, especially in children. In this study, we have discussed patterns of drug resistance in pediatric CNS-TB. [MATERIALS AND METHODS] Prospective observational study conducted on 100 children at a tertiary care center...
CNS tuberculosis; Tuberculous Meningitis; children; drug-resistance
0.358
62
Infectious Diseases; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,021
34,918,114
Predictors of persistent inflammation in children with familial Mediterranean fever.
Modern rheumatology
Mod Rheumatol
32
4
10.1093/mr/roab054
eng
2,022
7
1
null
null
null
[OBJECTIVES] Persistent inflammation is an insidious feature of familial Mediterranean fever (FMF) that may cause chronic complications. This study aimed to investigate the predictors of persistent inflammation in children with FMF. [METHODS] The medical charts of 1077 paediatric FMF patients were retrospectively colle...
Familial Mediterranean fever; paediatric rheumatology; persistent inflammation
0.777
71
Medicine; Rheumatology
Medicine
2,022
34,917,694
Triage of Persons With Tuberculosis Symptoms Using Artificial Intelligence-Based Chest Radiograph Interpretation: A Cost-Effectiveness Analysis.
Open forum infectious diseases
Open Forum Infect Dis
8
12
10.1093/ofid/ofab567
eng
2,021
12
null
2,021
12
15
[BACKGROUND] In settings without access to rapid expert radiographic interpretation, artificial intelligence (AI)-based chest radiograph (CXR) analysis can triage persons presenting with possible tuberculosis (TB) symptoms, to identify those who require additional microbiological testing. However, there is limited evid...
artificial intelligence; chest radiography; cost-effectiveness; deep learning; tuberculosis
1.317
74
Infectious Diseases; Oncology
Medicine
2,021
34,917,538
Repellent Efficacy of Eucalyptus globulus and Syzygium aromaticum Essential Oils against Malaria Vector, Anopheles stephensi (Diptera: Culicidae).
Iranian journal of public health
Iran J Public Health
50
8
10.18502/ijph.v50i8.6813
eng
2,021
8
null
null
null
null
[BACKGROUND] Mosquito species are highly considering as disease transmission as well as nuisance insects. One of the principal strategy to protect human from the mosquito bites is repellent agents. This study aimed to assess repellency of two organic essential oils, Eucalyptus globulus and Syzygium aromaticum from bite...
Anopheles stephensi; Eucalyptus globulus; Repellent activity; Syzygium aromaticum
0.344
60
Public Health, Environmental and Occupational Health
Medicine
2,021
34,917,299
Analgesic Effect of Bumetanide on Neuropathic Pain in Patients With Spinal Cord Injury.
Basic and clinical neuroscience
Basic Clin Neurosci
12
3
10.32598/bcn.12.3.2049.1
eng
2,021
null
null
2,021
5
1
[INTRODUCTION] The current study evaluated the analgesic effects of bumetanide as an adjunctive in the management of neuropathic pain following Spinal Cord Injury (SCI). The peripheral expression of Na-K-Cl Cotransporter-1 (NKCC1) and K-Cl Cotransporter-2 (KCC2) genes in polymorphonuclear lymphocytes (PMLs) was assesse...
Bumetanide; GammaAminobutyric Acid (GABA); K-Cl Cotransporter-2 (KCC2); Na-K-Cl Cotransporter-1 (NKCC1); Neuropathic pain; Spinal cord injury
0.369
31
Neurology; Cellular and Molecular Neuroscience
Medicine; Neuroscience
2,021
34,917,201
Metabolomic Profiling Identified Serum Metabolite Biomarkers and Related Metabolic Pathways of Colorectal Cancer.
Disease markers
Dis Markers
2021
null
10.1155/2021/6858809
eng
2,021
null
null
2,021
12
7
[BACKGROUND] The screening and early detection of colorectal cancer (CRC) still remain a challenge due to the lack of reliable and effective serum biomarkers. Thus, this study is aimed at identifying serum biomarkers of CRC that could be used to distinguish CRC from healthy controls. [METHODS] A prospective 1 : 2 indiv...
null
0.704
85
Biochemistry; Clinical Biochemistry; Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,916,827
Profiling Biomarkers in HIV Glomerular Disease - Potential for the Non-Invasive Diagnosis of HIVAN?
International journal of nephrology and renovascular disease
Int J Nephrol Renovasc Dis
14
null
10.2147/IJNRD.S331484
eng
2,021
null
null
2,021
12
8
[BACKGROUND] There is a wide spectrum of kidney pathology in human immunodeficiency virus (HIV) infection, affecting all structures of the kidney. The histology of HIV chronic kidney disease (CKD) is diverse, ranging from HIV-associated nephropathy (HIVAN) to focal glomerulosclerosis (FSGS), HIV-immune complex disease ...
HIV chronic kidney disease; NGAL; bone morphogenetic protein (BMP)-7; cystatin C; neutrophil gelatinase-associated lipocalin
0.571
42
Nephrology
Medicine
2,021
34,916,826
Preimplantation Genetic Diagnosis for DEB by Detecting a Novel Family-Specific COL7A1 Mutation in Vietnam.
The application of clinical genetics
Appl Clin Genet
14
null
10.2147/TACG.S344107
eng
2,021
null
null
2,021
12
9
[BACKGROUND] Epidermolysis bullosa (EB) is a disorder characterized by the appearance of blisters, erosions and wounds in response to minimal trauma. The disease manifests with noticeable symptoms ranging from mild to severe, classified into four major types: epidermolysis bullosa simplex (EBS), junctional epidermolysi...
COL7A1 gene mutation; EB; PGD; RDEB; epidermolysis bullosa; preimplantation genetic diagnosis; rare dystrophic epidermolysis bullosa; skin disorder
0.508
43
Genetics; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,916,754
Therapeutic Plasma Exchange in Pediatric Intensive Care Unit: A Single-center Experience.
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine
Indian J Crit Care Med
25
10
10.5005/jp-journals-10071-23985
eng
2,021
10
null
null
null
null
[AIM AND OBJECTIVE] To examine the clinical characteristics, indications, and complications of patients undergoing therapeutic plasma exchange (TPE) in our pediatric intensive care unit (PICU). [MATERIALS AND METHODS] Patients who underwent therapeutic plasma exchange between January 2018 and January 2020 in the PICU w...
Critically ill children; Hemolytic uremic syndrome; Pediatric intensive care; Plasma exchange
0.34
45
Critical Care and Intensive Care Medicine
Medicine
2,021
34,916,380
Effects of Goshajinkigan (TJ-107) for oxaliplatin-induced peripheral neurotoxicity using the functional assessment of cancer therapy/gynecologic oncology group 12-item neurotoxicity questionnaire in a Phase II, multicenter, randomized, double-blind, placebo-controlled trial.
Journal of cancer research and therapeutics
J Cancer Res Ther
17
6
10.4103/jcrt.JCRT_1123_19
eng
2,021
null
null
null
null
null
[BACKGROUND] The aim of the present study was to evaluate the efficacy of TJ-107 for oxaliplatin-induced peripheral neurotoxicity in prospective, multi-institutional, randomized, double-blind, placebo-controlled Phase II trials using the functional assessment of cancer therapy/gynecologic oncology group 12-item neuroto...
12-item neurotoxicity questionnaire; colorectal cancer; oxaliplatin; peripheral neurotoxicity
0.363
55
Medicine; Oncology; Radiology, Nuclear Medicine and Imaging
Medicine
2,021
34,977,919
Does Disease Activity After Induction Treatment With Biologics Predict Short-Term Outcome in Crohn's Disease and Ulcerative Colitis?
Inflammatory bowel diseases
Inflamm Bowel Dis
28
11
10.1093/ibd/izab331
eng
2,022
11
2
null
null
null
[BACKGROUND] Secondary loss of response to biological therapy is a challenge when treating Crohn's disease (CD) and ulcerative colitis (UC). Currently, no single marker has been found to be valid as a prognostic indicator of response to biologic therapy in patients with CD and UC. In this study, we aimed to assess whet...
Biologic Treatment; Biomarkers; Patient Reported Outcome Measures; Ulcerative Colitis
1.834
183
Gastroenterology; Immunology and Allergy
Medicine
2,022
34,977,632
Wide Variability of Pediatric Knee Arthroscopy Case Volume in Orthopaedic Surgery Residency.
Arthroscopy, sports medicine, and rehabilitation
Arthrosc Sports Med Rehabil
3
6
10.1016/j.asmr.2021.08.005
eng
2,021
12
null
2,021
9
14
[PURPOSE] The purpose of this study was to evaluate orthopaedic surgery resident case volume and variability for adult and pediatric knee arthroscopy from 2016 to 2020. [METHODS] The Accreditation Council for Graduate Medical Education surgical case log data from 2016 to 2020 for graduating United States orthopaedic su...
null
0.41
21
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Orthopedics and Sports Medicine; Public Health, Environmental and Occupational Health
Health Professions; Medicine
2,021
34,977,610
Top-100 Most-Cited Sports-Related Concussion Articles Focus on Symptomatology, Epidemiology, and Demographics.
Arthroscopy, sports medicine, and rehabilitation
Arthrosc Sports Med Rehabil
3
6
10.1016/j.asmr.2021.06.016
eng
2,021
12
null
2,021
8
18
[PURPOSE] To analyze the top-100 cited articles on sports-related concussions together with a bibliometric analysis to determine citations by year, level of evidence, study design, and several other factors related to the top referenced articles in sports concussions. [METHODS] The Clarivate Analytics Web of Knowledge ...
null
0.41
21
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Orthopedics and Sports Medicine; Public Health, Environmental and Occupational Health
Health Professions; Medicine
2,021
34,977,533
SARS-CoV-2 in hospital air as revealed by comprehensive respiratory viral panel sequencing.
Infection prevention in practice
Infect Prev Pract
4
1
10.1016/j.infpip.2021.100199
eng
2,022
3
null
2,021
12
27
[BACKGROUND] Nosocomially acquired severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection has become the most significant pandemic of our lifetime. Though its transmission was essentially attributed to droplets from an infected person, with recent advancements in knowledge, aerosol transmission see...
Hospital infection; Mutations; Next-generation sequencing; RT-PCR; SARS-CoV-2; Surveillance
0.544
16
Public Health, Environmental and Occupational Health; Infectious Diseases
Medicine
2,022
34,976,299
Calcium-/Calmodulin-Dependent Protein Kinase II (CaMKII) Inhibition Induces Learning and Memory Impairment and Apoptosis.
Oxidative medicine and cellular longevity
Oxid Med Cell Longev
2021
null
10.1155/2021/4635054
eng
2,021
null
null
2,021
12
23
[OBJECTIVES] Inhibition of calcium-/calmodulin- (CaM-) dependent kinase II (CaMKII) is correlated with epilepsy. However, the specific mechanism that underlies learning and memory impairment and neuronal death by CaMKII inhibition remains unclear. [MATERIALS AND METHODS] In this study, KN93, a CaMKII inhibitor, was use...
null
1.233
170
Biochemistry; Medicine; Aging; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,975,757
A Common R219K Variant of ATP-Binding Cassette Transporter A1 Gene Alters Atherometabolic Traits in Pregnant Women With Gestational Diabetes Mellitus.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
12
null
10.3389/fendo.2021.782453
eng
2,021
null
null
2,021
12
17
[BACKGROUND] ATP-binding cassette transporter A1 (ABCA1) has important roles in high-density lipoprotein (HDL) metabolism and reverse cholesterol transport, and is implicated in lipid-related disorders. Genetic variants are involved in the pathogenesis of gestational diabetes mellitus (GDM). The objective of this study...
ABCA1 gene; atherometabolic traits; gestational diabetes mellitus; obesity; single nucleotide polymorphism (SNP)
1.375
138
Endocrinology, Diabetes and Metabolism
Medicine
2,021
34,975,147
Implementation and outcomes of a standard dose dextrose gel protocol for management of transient neonatal hypoglycemia.
Journal of perinatology : official journal of the California Perinatal Association
J Perinatol
42
8
10.1038/s41372-021-01284-3
eng
2,022
8
null
2,022
1
3
[OBJECTIVE] The use of oral dextrose gel (DG) reduces IV dextrose use. Prior studies used weight-based dosing (WD), though barriers exist, and are mitigated using standard dosing (SD). Our outcomes include IV dextrose use, NICU admissions, breastfeeding, adverse events, and assessment of WD vs SD. [STUDY DESIGN] Retros...
null
0.98
119
Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine
2,022
34,975,043
Endosonographers performing on-site evaluation of solid pancreatic specimens for EUS-guided biopsy: A formal training method and learning curves.
Endoscopic ultrasound
Endosc Ultrasound
10
6
10.4103/EUS-D-21-00088
eng
2,021
null
null
null
null
null
[OBJECTIVES] This study aimed to examine the effects of a training program combining formal cytological curriculum and practical assessments on endosonographers and to determine how many operations were needed for training through learning curves. [METHODS] A formal cytological curriculum was implemented in November 20...
EUS-guided fine needle biopsy; ROSE; endoscopy training; solid pancreatic lesions
null
null
null
null
null
34,975,003
Autologous rib cartilage as implanted stiffener of phalloplasty: comparing three different methods.
Journal of plastic, reconstructive & aesthetic surgery : JPRAS
J Plast Reconstr Aesthet Surg
75
6
10.1016/j.bjps.2021.11.111
eng
2,022
6
null
2,021
12
7
[BACKGROUND] Maintaining the length, rigidity, and appearance of a reconstructed phallus in the long term has been challenging for phalloplasty and may depend on choosing the optimal implanted stiffener. The aim of this study was to determine the best type of stiffener for a reconstructed phallus regarding aesthetic an...
Autologous rib cartilage; Phalloplasty; Phallus reconstruction; Stiffener
null
null
null
null
null
34,974,950
Spinal muscular atrophy with predominant lower extremity (SMA-LED) with no signs other than pure motor symptoms at the intersection of multiple overlap syndrome.
Brain & development
Brain Dev
44
4
10.1016/j.braindev.2021.12.001
eng
2,022
4
null
2,021
12
30
[BACKGROUND] Mutations in the cytoplasmic dynein 1 heavy chain gene (DYNC1H1) have been associated with spinal muscular atrophy with predominant lower extremity involvement (SMA-LED), Charcot-Marie-Tooth 2O (CMT2O) disease, cortical migration anomalies, and autosomal dominant mental retardation13. SMA-LED phenotype-rel...
DYNC1H1; Gowers' sign; Lordosis; SMA-LED
null
null
null
null
null
34,974,850
Acute Traumatic Subdural Hematoma and Anticoagulation Risk.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
Can J Neurol Sci
50
2
10.1017/cjn.2021.518
eng
2,023
3
null
2,022
1
3
[BACKGROUND] Anticoagulation is used to prevent thromboembolic events. It is a common practice to hold anticoagulation in the first few days following a traumatic brain injury (TBI) with intracranial hemorrhage. However, traumatic subdural hematomas (SDH) are prone to re-hemorrhage long after the trauma. Data are scarc...
Anticoagulation; Brain injury; Head trauma; Subdural hematoma; Traumatic brain injury
null
null
null
null
null
34,974,835
Sustainability of weight loss from a family-centered pediatric weight management program integrated in primary care.
BMC health services research
BMC Health Serv Res
22
1
10.1186/s12913-021-07361-9
eng
2,022
1
2
2,022
1
2
[BACKGROUND] A 6-month pediatric weight loss program showed modest success, but the sustainability of this success after 12 months was unclear. The present study aims tomeasure the medium-term effectiveness of family-based weight management in pediatric primary care to reduce body weight in children living with obesity...
Body mass index; Family-centered; Obesity; Sustainability; Weight management
0.964
157
Health Policy
Medicine
2,022
34,974,713
Prehospital Tourniquet Use Should be a Trauma Team Activation Criterion.
The American surgeon
Am Surg
89
5
10.1177/00031348211060422
eng
2,023
5
null
2,022
1
3
[PURPOSE] Prehospital tourniquet application is not a standard trauma team activation (TTA) criterion recommended by the ACS COT. Tourniquet use has seen a resurgence recently with associated risks and benefits of more liberal usage. Our institution added tourniquet application as TTA criterion in January 2019. This st...
null
null
null
null
null
null
34,974,574
Treatment-related mortality in children with acute lymphoblastic leukaemia in a low-middle income country.
JPMA. The Journal of the Pakistan Medical Association
J Pak Med Assoc
71
10
10.47391/JPMA.796
eng
2,021
10
null
null
null
null
[OBJECTIVE] To determine the proportion of treatment-related mortality among mortalities of paediatric acute lymphoblastic leukaemia and to identify probable causes and risk factors. [METHODS] The observational retrospective study was conducted in February-March 2019 at the Department of Paediatric Haematology-Oncology...
null
null
null
null
null
null
34,974,566
Phylogenetic and sequencing analysis of Chikungunya virus strains from local Pakistani population.
JPMA. The Journal of the Pakistan Medical Association
J Pak Med Assoc
71
10
10.47391/JPMA.01-166
eng
2,021
10
null
null
null
null
[OBJECTIVE] To outline the genotype of Chikungunya virus strains and to form their phylogenetic tree. [METHODS] The cross-sectional study was conducted at the Armed Forces Institute of Pathology, Rawalpindi, Pakistan, from August 2016 to September 2017, and comprised suspected Chikungunya samples. The viral ribonucleic...
null
null
null
null
null
null
34,974,379
Idiopathic normal pressure hydrocephalus; treatment and outcome in the Region of Southern Denmark.
Clinical neurology and neurosurgery
Clin Neurol Neurosurg
213
null
10.1016/j.clineuro.2021.107107
eng
2,022
2
null
2,021
12
29
[OBJECTIVE] Idiopathic normal pressure hydrocephalus (iNPH) is a prevalent and cost-effective disease to treat. However, no gold standard exists to confidently select patients for shunt surgery. The aim of this study was to investigate how patients with suspected iNPH at our center responded to shunt surgery and to com...
CSF biomarkers; Dementia and related disorders; Neurodegenerative disorders; Neurogeriatrics; Neuroimaging
0.538
89
Medicine; Surgery; Neurology
Medicine
2,022
34,974,275
Ear reconstruction research using animal models: The effect of fat grafting on costal cartilage stents.
International journal of pediatric otorhinolaryngology
Int J Pediatr Otorhinolaryngol
153
null
10.1016/j.ijporl.2021.111016
eng
2,022
2
null
2,021
12
28
[OBJECT] For congenital microtia patients with a depressed mastoid area, it is unclear whether autologous fat grafting to fill the depressed area of the cheek will affect the survival of the subsequent grafted costal cartilage stent. An animal model was used for in vivo research to provide guidance for clinical applica...
Cartilage; Chondrocytes; Fat graft; Mastoid depression; Microtia
0.554
96
Medicine; Otorhinolaryngology; Pediatrics, Perinatology and Child Health
Medicine
2,022
34,974,268
Insights from system dynamics applications in addiction research: A scoping review.
Drug and alcohol dependence
Drug Alcohol Depend
231
null
10.1016/j.drugalcdep.2021.109237
eng
2,022
2
1
2,021
12
24
[BACKGROUND AND AIMS] Substance misuse and use disorders are dynamic and complex problems, situated within systems of interacting social, environmental, and neurobiological factors. System dynamics (SD) methods broaden, test, and improve understanding of complex systems and can help inform effective action. We sought t...
Addiction; Alcohol; Opioids; Polysubstance use; Substance use disorder; Systems thinking
1.562
193
Pharmacology; Pharmacology; Psychiatry and Mental Health; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
34,973,892
Objective Assessment of Pathological Voice Using Artificial Intelligence Based on the GRBAS Scale.
Journal of voice : official journal of the Voice Foundation
J Voice
38
3
10.1016/j.jvoice.2021.11.021
eng
2,024
5
null
2,021
12
30
[OBJECTIVES] The validity and reliability of the psychological assessment of auditory perceptions, as typified by the grade, roughness, breathiness, asthenia, and strain (GRBAS) scale, have been widely recognized. However, due to their subjective nature, inter- and intra-examiner reliability are unavoidable. In this st...
Artificial Intelligence; GRBAS; Pathological Voice; Voice disorder
0.573
114
LPN and LVN; Otorhinolaryngology; Speech and Hearing
Health Professions; Medicine; Nursing
2,024
34,973,077
Effect of dose adjustments on the efficacy and safety of tofacitinib in patients with rheumatoid arthritis: a post hoc analysis of an open-label, long-term extension study (ORAL Sequel).
Clinical rheumatology
Clin Rheumatol
41
4
10.1007/s10067-021-05908-z
eng
2,022
4
null
2,022
1
1
[INTRODUCTION/OBJECTIVES] We assess the impact of switching versus staying on the same tofacitinib dose on efficacy and safety in patients with rheumatoid arthritis (RA). [METHODS] ORAL Sequel was an open-label, long-term extension study of patients with RA receiving tofacitinib 5 or 10 mg BID for up to 9.5 years. Tofa...
Dosing; Post hoc analysis; Rheumatoid arthritis; Tofacitinib
0.864
104
Medicine; Rheumatology
Medicine
2,022
34,972,903
The Burden on Carers with Multiple Sclerosis.
Advances in experimental medicine and biology
Adv Exp Med Biol
1337
null
10.1007/978-3-030-78771-4_19
eng
2,021
null
null
null
null
null
[BACKGROUND] The family members of patients with multiple sclerosis (MS) are called to become carers, playing a vital and difficult role in supporting the patients in their daily life. The aim of this study was to investigate the extent of the multidimensional burden on the carers of multiple sclerosis. [METHODS] Data ...
Burden- charge; Care; Caregiver; Family burden
null
null
null
null
null
34,972,747
Usefulness Analysis of Fraction of Exhaled Nitric Oxide for the Differential Diagnosis of Acute Cough.
In vivo (Athens, Greece)
In Vivo
36
1
10.21873/invivo.12723
eng
2,022
null
null
null
null
null
[BACKGROUND/AIM] Measuring the fraction of exhaled nitric oxide (FeNO) is useful in the diagnosis of asthma and cough variant asthma. The aim of this study was to clarify the significance of measuring the FeNO in the differential diagnosis of acute cough. [PATIENTS AND METHODS] We analyzed 80 patients who visited the c...
Acute cough; asthmatic cough; fraction of exhaled nitric oxide; infectious cough
null
null
null
null
null
34,972,595
A prospective observational cohort study and systematic review of 40 patients with mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome.
Seminars in arthritis and rheumatism
Semin Arthritis Rheum
52
null
10.1016/j.semarthrit.2021.10.007
eng
2,022
2
null
2,021
11
14
[OBJECTIVE] Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome is characterized by overlapping features of relapsing polychondritis (RP) and Behcet's disease (BD). To date, no studies have defined the clinical spectrum of disease in a cohort of patients with MAGIC syndrome. [METHODS] Adult patients withi...
Behcet's disease; Magic syndrome; Relapsing polychondritis
1.594
139
Anesthesiology and Pain Medicine; Rheumatology
Medicine
2,022
34,972,532
Circ_0000620 acts as an oncogenic factor in gastric cancer through regulating MMP2 expression via sponging miR-671-5p.
Journal of biological research (Thessalonike, Greece)
J Biol Res (Thessalon)
28
1
10.1186/s40709-021-00154-5
eng
2,021
12
31
2,021
12
31
[BACKGROUND] Gastric cancer (GC) is one of the most common cancers in the digestive system. Circular RNAs (circRNAs) have been found to function as important regulators in the pathogenesis of GC. This study focused on the biological role and molecular mechanism of circ_0000620 in GC progression. [METHODS] The expressio...
Angiogenesis; Gastric cancer; MMP2; Metastasis; circ_0000620; miR-671-5p
null
null
null
null
null
34,972,100
Supporting Ultra Poor People with Rehabilitation and Therapy among families of children with Cerebral Palsy in rural Bangladesh (SUPPORT CP): Protocol of a randomised controlled trial.
PloS one
PLoS One
16
12
10.1371/journal.pone.0261148
eng
2,021
null
null
2,021
12
31
[INTRODUCTION] Poverty is a key contributor to delayed diagnosis and limited access to early intervention and rehabilitation for children with cerebral palsy (CP) in rural Bangladesh. 97% of families of children with CP live below the poverty line in Bangladesh. Therefore, in low-and middle-income countries (LMICs), ef...
null
0.852
467
Multidisciplinary
Multidisciplinary
2,021
34,972,006
Quality of recovery and safety of deep intravenous sedation compared to general anesthesia in facial plastic surgery: A prospective cohort study.
American journal of otolaryngology
Am J Otolaryngol
43
2
10.1016/j.amjoto.2021.103352
eng
2,022
null
null
2,021
12
24
[BACKGROUND] Facial plastic surgical procedures are performed under either general anesthesia (GA) or sedation. GA is often associated with post-operative nausea and longer recovery, while deep sedation is thought to greatly facilitate perioperative patient comfort and expedite recovery. The objective of this study was...
Deep sedation; Facial plastic; General anesthesia; Recovery; Rhinoplasty
null
null
null
null
null
34,971,990
Factors associated with condom use in vaginal intercourse among Spanish adults with intellectual disability: Proposal for an explanatory model.
Research in developmental disabilities
Res Dev Disabil
121
null
10.1016/j.ridd.2021.104157
eng
2,022
2
null
2,021
12
28
[BACKGROUND] The prevention of HIV or other STIs in people with intellectual disabilities (ID) is a rarely studied subject even though this population group is at the same risk of infection as the general population. [AIMS] The present study aims to conduct a descriptive analysis of sexual behaviours and condom use fre...
Condom use; HIV; Intellectual disability; Sexually transmitted infections; Vaginal sex
0.774
117
Clinical Psychology; Developmental and Educational Psychology
Psychology
2,022
34,971,854
Novel gross deletion at the LHX4 gene locus in a child with growth hormone deficiency.
Growth hormone IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
Growth Horm IGF Res
62
null
10.1016/j.ghir.2021.101443
eng
2,022
2
null
2,021
12
16
[OBJECTIVE] To identify and characterize a novel deletion at the LHX4 gene locus in a proband with growth hormone deficiency (GHD). [METHODS] Long range polymerase chain reaction (PCR) amplification was used to confirm the suspected deletion and to identify the rough locations of the end points. Sanger sequencing was c...
Growth hormone deficiency; Heterozygous deletion; Homeodomain; LHX4
null
null
null
null
null
34,971,460
Magnetic resonance spectroscopic imaging of downfield proton resonances in the human brain at 3 T.
Magnetic resonance in medicine
Magn Reson Med
87
4
10.1002/mrm.29142
eng
2,022
4
null
2,021
12
31
[PURPOSE] To develop an MRSI technique capable of mapping downfield proton resonances in the human brain. [METHODS] A spectral-spatial excitation and frequency-selective refocusing scheme, in combination with 2D phase encoding, was developed for mapping of downfield resonances without any perturbation of the water magn...
MR spectroscopic imaging; downfield; human brain
1.349
257
Radiology, Nuclear Medicine and Imaging
Medicine
2,022
34,971,362
Human Papillomavirus Antibody Levels Following Vaccination or Natural Infection Among Young Men Who Have Sex With Men.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Clin Infect Dis
75
2
10.1093/cid/ciab1052
eng
2,022
8
25
null
null
null
[BACKGROUND] Australia introduced a school-based gender-neutral human papillomavirus (HPV) vaccination program for girls and boys aged 12-13 years in 2013. We examined HPV type-specific antibody levels in unvaccinated young men who have sex with men (MSM) with natural infection and compared these with levels in those v...
HPV; immune response; immunization; natural infection; vaccination
3.995
398
Infectious Diseases; Microbiology
Medicine
2,022
34,970,836
The National Evaluation of Malawi's PMTCT Program (NEMAPP) study: 24-month HIV-exposed infant outcomes from a prospective cohort study.
HIV medicine
HIV Med
23
6
10.1111/hiv.13209
eng
2,022
7
null
2,021
12
30
[OBJECTIVES] Data on long-term HIV-free survival in breastfeeding, HIV-exposed infants (HEIs) are limited. The National Evaluation of Malawi's Prevention of Mother-to-Child Transmission (PMTCT) Program (NEMAPP), conducted between 2014 and 2018, evaluated mother-to-child transmission (MTCT) and infant outcomes up to 24 ...
HIV-exposed infants; HIV-free survival; Malawi; Option B+; disclosure; mother-infant pairs; prevention of mother-to-child transmission; treat all
0.989
88
Health Policy; Pharmacology; Infectious Diseases
Medicine
2,022
34,970,806
Decade of the dangers of multiple magnet ingestion in children: A retrospective review.
Journal of paediatrics and child health
J Paediatr Child Health
58
5
10.1111/jpc.15863
eng
2,022
5
null
2,021
12
30
[AIM] Magnet ingestion has become more frequent in children as magnetic toys and jewellery have been popularised, with the potential to cause significant morbidity. Our aim was to describe our experience at a tertiary paediatric surgical centre. [METHODS] Retrospective review of patients admitted with multiple magnet i...
foreign body ingestion; multiple magnet ingestion; paediatric
0.475
90
Pediatrics, Perinatology and Child Health
Medicine
2,022
34,970,758
Impact of mpMRI targeted biopsy on intraoperative nerve-sparing (NeuroSAFE) during robot-assisted laparoscopic radical prostatectomy.
The Prostate
Prostate
82
4
10.1002/pros.24295
eng
2,022
3
null
2,021
12
30
[BACKGROUND] The aim of our study was to evaluate the impact of prostate biopsy technique (transrectal ultrasound (US)-prostate biopsy (PBx) versus multiparametric magnetic resonance imaging (mpMRI) targeted prostate biopsy (MRI-PBx) on intraoperative nerve-sparing and the rate of secondary neurovascular-bundle resecti...
frozen section; localized; nerve-sparing (NeurSAFE); prostate cancer; secondary resection; ultrasound and MRI-guided prostate biopsy
1.015
138
Urology; Oncology
Medicine
2,022
34,970,742
Urinary microRNAs can predict response to abiraterone acetate in castration resistant prostate cancer: A pilot study.
The Prostate
Prostate
82
4
10.1002/pros.24293
eng
2,022
3
null
2,021
12
30
[BACKGROUND] Despite novel agents have been introduced to treat castration resistant prostate cancer (CRPC) during the last decade, up to one-third of CRPC patients face primary resistance to new generation compounds. Therefore, sensitive molecular tools are urgently needed for reliable treatment selection and response...
CRPC; androgen receptor; microRNAs; predictive biomarker; urine
1.015
138
Urology; Oncology
Medicine
2,022
34,970,481
High Circulating Sonic Hedgehog Protein Is Associated With Poor Outcome in EGFR-Mutated Advanced NSCLC Treated With Tyrosine Kinase Inhibitors.
Frontiers in oncology
Front Oncol
11
null
10.3389/fonc.2021.747692
eng
2,021
null
null
2,021
12
14
[INTRODUCTION] Growing preclinical evidence has suggested that the Sonic hedgehog (Shh) pathway is involved in resistance to tyrosine kinase inhibitor (TKI) therapy for EGFR-mutated (EGFRm) non-small cell lung cancer (NSCLC). However, little is known concerning the prognostic value of this pathway in this context. [MAT...
Sonic Hedgehog (Shh); biomarker; epidermal growth factor receptor (EGFR); non-small cell lung cancer (NSCLC); tyrosine kinase inhibitor (TKI)
1.291
156
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
34,969,914
SARS-CoV-2 Positivity in a Combat Sports Bubble.
Neurology
Neurology
98
12 Suppl 2
10.1212/01.wnl.0000801896.48894.7e
eng
2,022
1
4
null
null
null
[OBJECTIVE] The objective of this report is to describe a SARS-CoV-2 protocol and subsequent positivity rate for athletes and staff participating in combat sports events. [BACKGROUND] Combat sports are among the most challenging to protect against the transmission of communicable diseases. Sports neurologists are often...
null
2.537
422
Neurology
Medicine
2,022