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35,073,156
Allopurinol Initiation and All-Cause Mortality Among Patients With Gout and Concurrent Chronic Kidney Disease : A Population-Based Cohort Study.
Annals of internal medicine
Ann Intern Med
175
4
10.7326/M21-2347
eng
2,022
4
null
2,022
1
25
[BACKGROUND] Two recent randomized clinical trials of escalating doses of allopurinol for the progression of chronic kidney disease (CKD) reported no benefits but potentially increased risk for death. Whether the risk could occur in patients with gout and concurrent CKD remains unknown. [OBJECTIVE] To examine the relat...
null
3.845
445
Internal Medicine; Medicine
Medicine
2,022
35,072,769
Antiplaque and antigingivitis efficacy of medicated and non-medicated sugar-free chewing gum as adjuncts to toothbrushing: systematic review and network meta-analysis.
Clinical oral investigations
Clin Oral Investig
26
2
10.1007/s00784-021-04264-1
eng
2,022
2
null
2,022
1
24
[OBJECTIVE] This network meta-analysis (NMA) assessed the antiplaque and anti-inflammatory efficacy of different sugar-free chewing gums (SFCG) as adjuncts to toothbrushing. [MATERIAL AND METHODS] PubMed, Scopus, EMBASE, Web of Science, and CENTRAL databases were searched up to February 2021 to identify randomized cont...
Chewing gums; Dental plaque; Gingivitis; Oral health; Xylitol
0.91
108
Dentistry
Dentistry
2,022
35,072,415
Has the profile of heart transplantation recipients changed within the last three decades?
Swiss medical weekly
Swiss Med Wkly
152
null
10.4414/smw.2022.w30108
eng
2,022
1
17
2,022
1
21
[BACKGROUND] Heart transplantation remains the most durable treatment for patients with end-stage heart failure refractory to medical treatment. Central elements of the listing criteria for heart transplantation have remained largely unchanged in the last three decades whereas treatment of heart failure has significant...
null
null
null
null
null
null
35,072,406
Evaluation of Plasma Asprosin Concentration in Patients with Coronary Artery Disease.
Brazilian journal of cardiovascular surgery
Braz J Cardiovasc Surg
37
4
10.21470/1678-9741-2021-0003
eng
2,022
8
16
2,022
8
16
[INTRODUCTION] The goal of this study is to investigate the association between diagnosis and severity of coronary artery disease (CAD) and Asprosin level. [METHODS] Patients diagnosed with CAD who underwent conventional coronary angiography for the first time were included in the present study. The patients were divid...
Asprosin; Coronary Angiography; Coronary Artery Disease; Risk Factors; Severity of Illness Index
0.327
36
Cardiology and Cardiovascular Medicine; Medicine; Surgery
Medicine
2,022
35,072,097
Risk Stratification of Pulmonary Thromboembolism using Brain Natriuretic Peptide and Troponin I; a Brief Report.
Archives of academic emergency medicine
Arch Acad Emerg Med
10
1
10.22037/aaem.v10i1.1453
eng
2,022
null
null
2,022
1
8
[INTRODUCTION] Pulmonary thromboembolism (PTE) is one of the most prevalent medical disorders, with a notable annual fatality rate. This study aimed to evaluated the accuracy of serum pro-BNP and troponin I levels in PTE diagnosis. [METHODS] This cross-sectional study was implemented on 267 patients with suspected PTE ...
Brain; Computed Tomography Angiography; Natriuretic Peptide; Pulmonary Embolism; Troponin
0.745
26
Emergency Medicine
Medicine
2,022
35,072,046
Race, Income, and Medical Care Spending Patterns in High-Risk Primary Care Patients: Results From the STOP-DKD (Simultaneous Risk Factor Control Using Telehealth to Slow Progression of Diabetic Kidney Disease) Study.
Kidney medicine
Kidney Med
4
1
10.1016/j.xkme.2021.08.016
eng
2,022
1
null
2,021
10
26
[RATIONALE AND OBJECTIVE] Little is known about how socioeconomic status (SES) relates to the prioritization of medical care spending over personal expenditures in individuals with multiple comorbid conditions, and whether this relationship differs between Blacks and non-Blacks. We aimed to explore the relationship bet...
Chronic kidney disease; medical costs; medical spending; racial disparities
0.941
28
Nephrology; Internal Medicine
Medicine
2,022
35,071,957
Improving Care for Children with Bloody Diarrhea at Risk for Hemolytic Uremic Syndrome.
Pediatric quality safety
Pediatr Qual Saf
7
1
10.1097/pq9.0000000000000517
eng
2,022
null
null
2,022
1
21
[INTRODUCTION] Children with infectious bloody diarrhea are at an increased risk for developing hemolytic uremic syndrome (HUS). Early intervention may improve outcomes. This study evaluated the impact of a clinical pathway designed to identify those at risk for HUS, guide initial management, and provide decision suppo...
null
null
null
null
null
null
35,071,617
Online learning in nursing students: Satisfaction and barriers.
Journal of education and health promotion
J Educ Health Promot
10
null
10.4103/jehp.jehp_1221_20
eng
2,021
null
null
2,021
11
30
[BACKGROUND] The nationwide coronavirus (COVID-19) pandemic and ensuing lockdown has enforced institutions crosswise India to provisionally close to inhibit the spread of the virus and started online learning for students. To measure the level of satisfaction of nursing students with online learning and to identify the...
Barriers; online learning; satisfaction; students
0.331
30
Education; Medicine
Medicine; Social Sciences
2,021
35,071,611
Performance analysis of data mining algorithms for diagnosing COVID-19.
Journal of education and health promotion
J Educ Health Promot
10
null
10.4103/jehp.jehp_138_21
eng
2,021
null
null
2,021
11
30
[BACKGROUND] An outbreak of atypical pneumonia termed COVID-19 has widely spread all over the world since the beginning of 2020. In this regard, designing a prediction system for the early detection of COVID-19 is a critical issue in mitigating virus spread. In this study, we have applied selected machine learning tech...
Artificial intelligence; COVID-19; coronavirus; data mining; diagnosis; machine learning
0.331
30
Education; Medicine
Medicine; Social Sciences
2,021
35,071,609
Pharmaceutical nanotechnology: from the bench to the market.
Future journal of pharmaceutical sciences
Futur J Pharm Sci
8
1
10.1186/s43094-022-00400-0
eng
2,022
null
null
2,022
1
15
[BACKGROUND] Nanotechnology is considered a new and rapidly emerging area in the pharmaceutical and medicinal field. Nanoparticles, as drug delivery systems, impart several advantages concerning improved efficacy as well as reduced adverse drug reactions. [MAIN BODY] Different types of nanosystems have been fabricated ...
Applications; Characterization; Delivery systems; Fabrication; Nanotechnology
null
null
null
null
null
35,071,557
Application effect for a care bundle in optimizing nursing of patients with severe craniocerebral injury.
World journal of clinical cases
World J Clin Cases
9
36
10.12998/wjcc.v9.i36.11265
eng
2,021
12
26
null
null
null
[BACKGROUND] Severe craniocerebral injury (STBI) is a critical physical trauma caused by a sudden external force acting on the head. The condition is complex and changeable, and disability and mortality rates are high. Although the life of STBI patients can be saved through treatment, the sequelae of consciousness, spe...
Care bundle; Clinical application; Early rehabilitation; Emergency treatment; Severe craniocerebral injury
0.38
38
Medicine
Medicine
2,021
35,071,510
Influence of overweight and obesity on the mortality of hospitalized patients with community-acquired pneumonia.
World journal of clinical cases
World J Clin Cases
10
1
10.12998/wjcc.v10.i1.104
eng
2,022
1
7
null
null
null
[BACKGROUND] Obesity is associated with a better prognosis in patients with community-acquired pneumonia (the so-called obesity survival paradox), but conflicting results have been found. [AIM] To investigate the relationship between all-cause mortality and body mass index in patients with community-acquired pneumonia....
Body mass index; Community-acquired pneumonia; Mortality; Obesity; Overweight; Prognosis
null
38
Medicine
Medicine
2,022
35,071,493
Radiosensitizing effect of c-Met kinase inhibitor BPI-9016M in esophageal squamous cell carcinoma cells in vitro and in vivo.
Annals of translational medicine
Ann Transl Med
9
24
10.21037/atm-21-6586
eng
2,021
12
null
null
null
null
[BACKGROUND] c-Met is the receptor of hepatocyte growth factor (HGF) which plays a key role in inhibiting apoptosis. BPI-9016M is a small-molecule c-Met inhibitor that can promote apoptosis and enhance the cytotoxicity of various DNA-damaging agents. Here, we evaluated the radiosensitizing potential of BPI-9016M in Eca...
BPI-9016M; c-Met; esophageal squamous cell carcinoma (ESCC); radiosensitivity
null
null
null
null
null
35,071,492
MiR-499a-5p promotes 5-FU resistance and the cell proliferation and migration through activating PI3K/Akt signaling by targeting PTEN in pancreatic cancer.
Annals of translational medicine
Ann Transl Med
9
24
10.21037/atm-21-6556
eng
2,021
12
null
null
null
null
[BACKGROUND] Pancreatic cancer (PC) can be considered a representative cancer type of the human body. As demonstrated by some studies, microRNA (miR)-499 is dysregulated in various cancer types including PC, for which chemotherapy involving 5-fluorouracil (5-FU) has long been considered the first-line therapy. However,...
5-fluorouracil resistance (5-FU resistance); MiRNA-499a-5p; PI3K/Akt; pancreatic cancer (PC); proliferation
null
null
null
null
null
35,071,472
Effectiveness and safety of catheter removal alone versus standard anticoagulation therapy after catheter removal for peripherally inserted central catheter (PICC)-related thrombosis.
Annals of translational medicine
Ann Transl Med
9
24
10.21037/atm-21-5884
eng
2,021
12
null
null
null
null
[BACKGROUND] Currently, peripherally inserted central catheters (PICCs) are widely used; however, there are associated problems due to catheter-related thrombosis (CRT). According to the existing literature and guidelines, 3-6 months of anticoagulation therapy is recommended, but these recommendations are based on anal...
Peripherally inserted central catheter (PICC); anticoagulation; thrombosis
null
null
null
null
null
35,071,066
Evaluation of Pediatric Hydrocephalus: Clinical, Surgical, and Outcome Perspective in a Tertiary Center.
Asian journal of neurosurgery
Asian J Neurosurg
16
4
10.4103/ajns.AJNS_132_21
eng
2,021
null
null
2,021
12
18
[CONTEXT] Pediatric hydrocephalus (PH) results in significant clinical and psychosocial morbidity in pediatric population. [AIMS] The aims of the study are to evaluate clinical, surgical, and outcome perspective of PH patients of age 12 years. [SETTINGS AND DESIGN] This is a retrospective cohort study. [MATERIALS AND M...
Congenital hydrocephalus; endoscopic third ventriculostomy; pediatric hydrocephalus; postinfectious hydrocephalus; survival; ventriculoperitoneal shunt
null
null
null
null
null
35,070,900
Promotion of allogeneic parathyroid cell transplantation in rats with hypoparathyroidism.
Gland surgery
Gland Surg
10
12
10.21037/gs-21-809
eng
2,021
12
null
null
null
null
[BACKGROUND] This study sought to establish a rat model of hypoparathyroidism by removing the rat parathyroid glands, and compare the effects of different transplantation sites and transplantation methods using a primary culture of parathyroid cells in vitro on the hormone secretion of the model rats. [METHODS] Male Sp...
Parathyroid; allogeneic transplantation; primary cell culture
0.462
43
Surgery
Medicine
2,021
35,070,853
Insulin resistance indexes of grazing cows and mineral or vitamin supplementation under tropical conditions.
Open veterinary journal
Open Vet J
11
4
10.5455/OVJ.2021.v11.i4.8
eng
2,021
null
null
2,021
11
2
[BACKGROUND] During the transition period in dairy cows, metabolic changes occur, many of which are related to energy metabolism, which causes metabolic diseases or productive alterations. [AIM] The objective of the present work was to evaluate two mineral and vitamin supplementations related to metabolic regulation me...
Dairy cows; Insulin resistance; Metabolism; Nutrition factors; Transition period
0.335
22
Veterinary
Veterinary
2,021
35,070,808
"Body modification: piercing and tattooing in congenital heart disease patients", decoration or disaster?-a narrative review.
Cardiovascular diagnosis and therapy
Cardiovasc Diagn Ther
11
6
10.21037/cdt-21-458
eng
2,021
12
null
null
null
null
[OBJECTIVE] Tattoos and piercings are types of body art, which are gaining popularity over the last decades. An increasing number of adolescents and adults with congenital heart disease (CHD) have piercings or tattoos. This review will provide prudent information on the subject for affected patients and health care pro...
Body modification; congenital heart disease (CHD); endocarditis; piercing; tattoo
0.655
47
Cardiology and Cardiovascular Medicine
Medicine
2,021
35,070,790
The association between intravascular ultrasound-derived echo-attenuation and quantitative flow ratio in intermediate coronary lesions.
Cardiovascular diagnosis and therapy
Cardiovasc Diagn Ther
11
6
10.21037/cdt-21-402
eng
2,021
12
null
null
null
null
[BACKGROUND] The clinical relevance of moderate coronary stenosis is determined by its morphological characteristics and physiological significance. We investigated the relationship between high-risk plaque characteristics detected by intravascular ultrasound and functional significance assessed with quantitative flow ...
null
0.655
47
Cardiology and Cardiovascular Medicine
Medicine
2,021
35,070,410
Analysis of dynamic molecular networks: the progression from colorectal adenoma to cancer.
Journal of gastrointestinal oncology
J Gastrointest Oncol
12
6
10.21037/jgo-21-674
eng
2,021
12
null
null
null
null
[BACKGROUND] Colorectal cancer (CRC) is one of the deadliest cancers worldwide. It is the fourth most deadly cancer in the world with nearly 900,000 people die every year, the progression of polyps into cancer as one of its most common developmental pathways. [METHODS] This study obtained gene chip data collections fro...
Bioinformatics; colorectal cancer (CRC); dynamic molecular network; polyps; screening
0.697
60
Gastroenterology; Oncology
Medicine
2,021
35,070,392
LINC00857 promotes the proliferation of pancreatic cancer via MET, STAT3, and CREB.
Journal of gastrointestinal oncology
J Gastrointest Oncol
12
6
10.21037/jgo-21-723
eng
2,021
12
null
null
null
null
[BACKGROUND] Long non-coding RNA (lncRNA) LINC00857 promotes cell proliferation in various cancers and is overexpressed in pancreatic cancer (PC). However, the role of LINC00857 in PC is yet to be clarified. [METHODS] In this study, we used Gene Expression Profiling Interactive Analysis (GEPIA) to investigate transcrip...
LINC00857; mesenchymal-epithelial transition (MET); pancreatic cancer; proliferation
0.697
60
Gastroenterology; Oncology
Medicine
2,021
35,070,311
Factors associated with prolonged length of hospital stay among COVID-19 cases admitted to the largest treatment center in Eastern Ethiopia.
SAGE open medicine
SAGE Open Med
10
null
10.1177/20503121211070366
eng
2,022
null
null
2,022
1
19
[INTRODUCTION] The hospital admissions load and how long each patient will stay in the hospital should be known to prevent the overwhelming of the health system during coronavirus disease 2019 era. Even though the length of hospital stay could vary due to different factors, the factors that affect the stay are not well...
Ethiopia; Hospital length of stay; SARS-CoV-2; coronavirus; factors
0.613
41
Medicine
Medicine
2,022
35,070,017
Accuracy of virtual chromoendoscopy in differentiating gastric antral vascular ectasia from portal hypertensive gastropathy: A proof of concept study.
World journal of hepatology
World J Hepatol
13
12
10.4254/wjh.v13.i12.2168
eng
2,021
12
27
null
null
null
[BACKGROUND] Accurate detection of gastric antral vascular ectasia (GAVE) is critical for proper management of cirrhosis-related gastrointestinal bleeding. However, endoscopic diagnosis of GAVE can be challenging when GAVE overlaps with severe portal hypertensive gastropathy (PHG). [AIM] To determine the added diagnost...
Endoscopy; Gastric antral vascular ectasia; Portal hypertensive gastropathy; Virtual chromoendoscopy
null
null
null
null
null
35,069,447
Decrease in Salivary Serotonin in Response to Probiotic Supplementation With Saccharomyces boulardii in Healthy Volunteers Under Psychological Stress: Secondary Analysis of a Randomized, Double-Blind, Placebo-Controlled Trial.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
12
null
10.3389/fendo.2021.800023
eng
2,021
null
null
2,022
1
6
[BACKGROUND] Bacterial probiotics are thought to exert a serotonergic effect relevant to their potential antidepressant and pro-cognitive action, but yeast probiotics have not been tested. The aim of the present study was to determine whether 30-day supplementation with Saccharomyces boulardii affects the level of sali...
Saccharomyces boulardii; anxiety; depression; dietary supplementation; probiotic; salivary serotonin; symapathoadrenal markers; yeast
1.375
138
Endocrinology, Diabetes and Metabolism
Medicine
2,021
35,068,930
Obstructive Sleep Apnea is Associated with an Increased Prevalence of Polycythemia in Patients with Chronic Obstructive Pulmonary Disease.
International journal of chronic obstructive pulmonary disease
Int J Chron Obstruct Pulmon Dis
17
null
10.2147/COPD.S338824
eng
2,022
null
null
2,022
1
15
[PURPOSE] Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) are associated with polycythemia. However, there still remain unanswered questions about the relationship between overlap syndrome (OVS), where OSA and COPD coexist, and polycythemia. Here, we aimed to establish the prevalence of p...
chronic obstructive pulmonary disease; obstructive sleep apnea; overlap syndrome; polycythemia
null
null
null
null
null
35,068,458
Toward Pre-Diagnostic Detection of Dementia in Primary Care.
Journal of Alzheimer's disease : JAD
J Alzheimers Dis
86
1
10.3233/JAD-215242
eng
2,022
null
null
null
null
null
[BACKGROUND] Preventing dementia warrants the pragmatic engagement of primary care. [OBJECTIVE] This study predicted conversion to dementia 12 months before diagnosis with indicators that primary care can utilize within the practical constraints of routine practice. [METHODS] The study analyzed data from the Alzheimer'...
dementia; pre-diagnostic detection; prevention; primary care; screening
1.146
188
Clinical Psychology; Geriatrics and Gerontology; Medicine; Psychiatry and Mental Health; Neuroscience
Medicine; Neuroscience; Psychology
2,022
35,068,455
An Automated Toolbox to Predict Single Subject Atrophy in Presymptomatic Granulin Mutation Carriers.
Journal of Alzheimer's disease : JAD
J Alzheimers Dis
86
1
10.3233/JAD-215447
eng
2,022
null
null
null
null
null
[BACKGROUND] Magnetic resonance imaging (MRI) measures may be used as outcome markers in frontotemporal dementia (FTD). [OBJECTIVES] To predict MRI cortical thickness (CT) at follow-up at the single subject level, using brain MRI acquired at baseline in preclinical FTD. [METHODS] 84 presymptomatic subjects carrying Gra...
Frontotemporal dementia; granulin; magnetic resonance imaging; mutation; preclinical; presymptomatic
1.146
188
Clinical Psychology; Geriatrics and Gerontology; Medicine; Psychiatry and Mental Health; Neuroscience
Medicine; Neuroscience; Psychology
2,022
35,068,061
Men suffering from category III chronic prostatitis may benefit from N-acetylcysteine as an adjunct to alpha-blockers.
Lower urinary tract symptoms
Low Urin Tract Symptoms
14
3
10.1111/luts.12425
eng
2,022
5
null
2,022
1
23
[OBJECTIVE] We designed this study to investigate the potential use of N-acetylcysteine (NAC) as an adjunct to alpha-blockers in the treatment of category III chronic prostatitis (CP). [METHODS] Sixty-three men with category III CP with a National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) total ...
N-acetylcysteine; chronic pelvic pain; chronic prostatitis; inflammation; oxidative stress
null
null
null
null
null
35,068,025
The relation between gestures and stuttering in individuals with Down syndrome.
Journal of applied research in intellectual disabilities : JARID
J Appl Res Intellect Disabil
35
3
10.1111/jar.12980
eng
2,022
5
null
2,022
1
24
[BACKGROUND] Evidence shows that neurotypical individuals who stutter use fewer gestures than those who do not stutter. Presently, no research exists about the interaction of stuttering and gestures in individuals with Down syndrome. [METHOD] Twenty-nine individuals with Down syndrome (7-19 years) of whom 16 stuttered ...
Down syndrome; gesture-speech relationship; gestures; stuttering
0.836
79
Education; Developmental and Educational Psychology
Psychology; Social Sciences
2,022
35,067,964
Development of patient-centric eating advice for complete denture wearers.
Gerodontology
Gerodontology
40
1
10.1111/ger.12618
eng
2,023
3
null
2,022
1
23
[BACKGROUND] Edentulous people eat less healthily, and wearing dentures impairs eating function and enjoyment. [OBJECTIVE] To apply a sequential approach to integrate scientific evidence, and patient and professional experience to co-develop intervention to support better eating with dentures. [METHODS] Focus groups, t...
mastication; nutrition; prosthodontics; tooth loss
0.609
69
Dentistry; Geriatrics and Gerontology
Dentistry; Medicine
2,023
35,067,790
Weight Tracking as a Novel Prognostic Marker After Pancreatectomy.
Annals of surgical oncology
Ann Surg Oncol
29
6
10.1245/s10434-022-11325-6
eng
2,022
6
null
2,022
1
23
[BACKGROUND] Objective measures of post-pancreatectomy weight change for pancreatic ductal adenocarcinoma (PDAC) have not been extensively studied for long-term outcomes. We used weight measurements in our institutional medical record to analyze trends in post-pancreatectomy weight and determine the association with di...
null
1.133
210
Surgery; Oncology
Medicine
2,022
35,067,505
Prevalent Drug Usage Practices in Adults and Children With Idiopathic Inflammatory Myopathies: Registry-Based Analysis From the MyoCite Cohort.
Journal of clinical rheumatology : practical reports on rheumatic musculoskeletal diseases
J Clin Rheumatol
28
2
10.1097/RHU.0000000000001813
eng
2,022
3
1
null
null
null
[BACKGROUND] Idiopathic inflammatory myopathies (IIMs) form a heterogeneous group of disorders with a deficit of quality evidence regarding its management. Therefore, we aimed to explore the prevalent treatment practices in the MyoCite cohort from India. [METHODS] Drug usage patterns, their predictors, drug retention r...
null
0.616
63
Medicine; Rheumatology
Medicine
2,022
35,067,458
Midwife-led continuity of care increases women's satisfaction with antenatal, intrapartum, and postpartum care: North Shoa, Amhara regional state, Ethiopia: A quasi-experimental study.
Women and birth : journal of the Australian College of Midwives
Women Birth
35
6
10.1016/j.wombi.2022.01.005
eng
2,022
11
null
2,022
1
20
[BACKGROUND] The provision of midwife-led continuity of care (MLCC) is effective in high-resource settings in improving maternal satisfaction. This study aimed to evaluate the effect of MLCC on women's satisfaction with care in a low-income/resource setting. [METHOD] A study with a quasi-experimental design was conduct...
Continuity of care; Ethiopia; Midwife-led continuity of care; Midwifery; North Shoa; Satisfaction with care
1.033
63
Maternity and Midwifery; Medicine; Obstetrics and Gynecology
Medicine; Nursing
2,022
35,067,206
Outcome in children with newly diagnosed rheumatic heart disease in Indonesia.
Paediatrics and international child health
Paediatr Int Child Health
41
4
10.1080/20469047.2022.2027324
eng
2,021
11
null
2,022
1
23
[BACKGROUND] Rheumatic heart disease (RHD) is associated with high morbidity and mortality, especially in those with severe RHD or progression of valvular disease (VD). Evaluation of the factors that predict valvular progression is important in order to improve clinical outcome. [AIM] To evaluate outcome and clinical p...
Indonesia; Predictor; rheumatic heart disease; valvular disease progression
0.365
57
Pediatrics, Perinatology and Child Health
Medicine
2,021
35,067,160
"I'm Not a Good Drug Dealer": Styles of Buprenorphine Diversion in a Multisite Qualitative Study.
Substance use misuse
Subst Use Misuse
57
3
10.1080/10826084.2021.2019775
eng
2,022
null
null
2,022
1
22
[BACKGROUND] Against the backdrop of the U.S. opioid epidemic, there has been a concerted movement to improve access to buprenorphine maintenance therapy (BMT). In Pennsylvania, where overdose mortality increased 65% between 2015 and 2017, over $75 million has been appropriated toward BMT since 2016. Concurrently, effo...
Buprenorphine; diversion; non-medical prescription drug use; opioid analgesics; qualitative
null
null
null
null
null
35,066,942
Dimensional ridge changes in conjunction with four implant timing protocols and two types of soft tissue grafts: A pilot pre-clinical study.
Journal of clinical periodontology
J Clin Periodontol
49
4
10.1111/jcpe.13594
eng
2,022
4
null
2,022
1
31
[AIM] To determine the effect of (1) implant placement timing and (2) the type of soft tissue graft in terms of ridge profile changes. [MATERIALS AND METHODS] Four implant treatment modalities were applied in the mesial root areas of the third and fourth mandibular premolars of 10 mongrel dogs alongside connective-tiss...
connective tissue graft; implant placement; tissue remodelling; volume-stable cross-linked collagen matrix
2.407
187
Periodontics
Dentistry
2,022
35,066,809
LncRNA-GAS5/miR-382-3p axis inhibits pulmonary artery remodeling and promotes autophagy in chronic thromboembolic pulmonary hypertension.
Genes genomics
Genes Genomics
44
4
10.1007/s13258-021-01202-z
eng
2,022
4
null
2,022
1
23
[BACKGROUND] We have clarified the role of miR-382-3p in chronic thromboembolic pulmonary hypertension (CTEPH), but what is less clear lies in its upstream regulatory mechanism. [OBJECTIVE] To explore the regulation mechanism of GAS5/miR-382-3p axis on CTEPH. [METHODS] In vitro, we constructed cell models by treating P...
Autophagy; Chronic thromboembolic pulmonary hypertension; Long non-coding RNA GAS5; miR-382-3p
null
null
null
null
null
35,116,587
Effects of a combined treatment regimen consisting of Hsp90 inhibitor DS-2248 and radiation in vitro and in a tumor mouse model.
Translational cancer research
Transl Cancer Res
10
6
10.21037/tcr-21-71
eng
2,021
6
null
null
null
null
[BACKGROUND] Heat shock protein 90 (HSP90) is a molecular chaperone that is responsible for the conformational maintenance of several client proteins that play important roles in DNA damage repair, apoptosis following radiation, and resistance to radiation therapy. DS-2248 (tricyclic pyrazolopyrimidine derivative) is a...
DNA-double-strand break; DS-2248; Hsp90 inhibitor; Radiation therapy; radiosensitizer
0.185
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,116,554
The expression of myosin-regulated light chain interacting protein (MYLIP) in lung cancer and its inhibitory effects on lung carcinomas.
Translational cancer research
Transl Cancer Res
10
5
10.21037/tcr-21-606
eng
2,021
5
null
null
null
null
[BACKGROUND] This study explored the relationship between myosin-regulated light chain interacting protein (MYLIP) and the prognosis of lung cancer and its effects on the proliferation, migration, and invasion of lung cancer cells. [METHODS] Bioinformatics analyses of databases were conducted to explore the relationshi...
cell invasion; cell migration; cell proliferation; lung cancer; nude mice model
0.185
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,116,528
Association between insulin-like growth factor 1 gene rs5742612 polymorphism and malignant tumor susceptibility: a meta-analysis.
Translational cancer research
Transl Cancer Res
10
5
10.21037/tcr-20-2005
eng
2,021
5
null
null
null
null
[BACKGROUND] Malignant tumor is a serious threat to human health and life, which is a difficult problem in the world. Insulin-like growth factor 1 (IGF1) is an important mitotic factor in vivo. It usually acts in the way of autocrine and paracrine to control the proliferation, differentiation, and apoptosis of various ...
Insulin-like growth factor 1 (IGF1); gene rs5742612; malignant tumor; meta-analysis; polymorphism
0.185
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,116,448
A bibliometric analysis and visualization of photothermal therapy on cancer.
Translational cancer research
Transl Cancer Res
10
3
10.21037/tcr-20-2961
eng
2,021
3
null
null
null
null
[BACKGROUND] Cancer is one of the most lethal diseases in the world, and photothermal therapy was reported recently as a new and effective therapy for cancer. This study offers the bibliometric and visualization analysis of photothermal therapy on cancer. [METHODS] A record of 6,233 papers in this field from 1995 to 20...
CiteSpace; Photothermal therapy; cancer; nanomaterials; visualization analysis
0.185
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,116,414
The risks and trends of cardiac-specific mortality associated with chemotherapy or radiotherapy in a large cohort of non-elderly patients with non-small cell lung cancer.
Translational cancer research
Transl Cancer Res
10
2
10.21037/tcr-20-2981
eng
2,021
2
null
null
null
null
[BACKGROUND] Anticancer treatment-related heart events is a major concern. However, the frequent occurrence time of cardiac death and the association between cardiac-specific mortality (CSM) and various lung lobes among non-elderly non-small cell lung cancer (NSCLC) patients after chemotherapy or radiotherapy (RT) are ...
Non-small cell lung cancer (NSCLC); cardiac mortality; chemotherapy; non-elderly; radiotherapy (RT)
0.185
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,116,410
Rab25 acts as an oncogene and participates in the regulation of aerobic glycolysis via PKM2 in gastric adenocarcinoma.
Translational cancer research
Transl Cancer Res
10
2
10.21037/tcr-20-2597
eng
2,021
2
null
null
null
null
[BACKGROUND] Rab25, a hub node of protein-protein interaction networks, has become one of the most popular tumor-associated proteins. Pyruvate kinase (PK) is the main rate-limiting enzyme in the glycolysis pathway and plays a significant role in the regulation of Warburg effect. In this study, we aimed to characterize ...
PKM2; Rab25; aerobic glycolysis; gastric adenocarcinoma (GAC); phosphorylation
0.185
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,116,377
ADRB2 is a potential protective gene in breast cancer by regulating tumor immune microenvironment.
Translational cancer research
Transl Cancer Res
10
12
10.21037/tcr-21-1257
eng
2,021
12
null
null
null
null
[BACKGROUND] Breast cancer (BRCA) is the leading cause of cancer death among females. Studies suggested that β-adrenoceptors involved in tumor progression by regulating immune system. However, how ADRB2 affects the immune infiltration in BRCA is still being unraveled. [METHODS] Expressions of ADRB2 in multiple tissues,...
ADRB2; Breast cancer (BRCA); bioinformatic analysis; immune infiltration; tumor immune microenvironment
0.185
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,116,368
The effect of gonadal and extragonadal malignant cancers on sperm quality.
Translational cancer research
Transl Cancer Res
10
12
10.21037/tcr-21-1697
eng
2,021
12
null
null
null
null
[BACKGROUND] Many studies have reported that testicular germ cell tumours (TGCTs) give rise to a decrease in sperm production and may further lead to infertility. However, little is known regarding sperm production in extragonadal germ cell tumours (EGCTs). We have studied the differences in the characteristics and spe...
Testicular germ cell tumours (TGCTs); cryopreservation; extragonadal germ cell tumours (EGCTs); semen analysis; spermatozoa
0.185
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,116,357
Functional clustering analysis identifies specific subtypes of aldehyde dehydrogenase associated with glioma immunity.
Translational cancer research
Transl Cancer Res
10
12
10.21037/tcr-21-1160
eng
2,021
12
null
null
null
null
[BACKGROUND] As a novel cancer stem cell marker, the biological functions of aldehyde dehydrogenases (ALDH enzymes) are a hot topic in current cancer research. However, there is a lack of systematic understanding of ALDH enzymes, which has hindered the translation of targeted therapies from bench work into the clinic. ...
Acetaldehyde dehydrogenase (ALDH); DNA repair; glioma; prognosis; tumor immunity
0.185
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,116,259
Microarray analysis of miRNA based on the regional lymph node metastasis status of esophageal squamous cell carcinoma.
Translational cancer research
Transl Cancer Res
10
1
10.21037/tcr-20-1969
eng
2,021
1
null
null
null
null
[BACKGROUND] Tendency toward extensive regional lymph node metastasis (LNM) is an important clinical characteristic of esophageal squamous cell carcinoma (ESCC) and differs greatly between patients. MicroRNAs (miRNAs) are involved in the invasion and metastasis of ESCC. We performed a microarray analysis of miRNAs base...
Esophageal squamous cell carcinoma (ESCC); lymph node metastasis (LNM); microRNAs (miRNAs); microarray analysis
0.185
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,116,032
Identification of Inflammation-Related Biomarker Pro-ADM for Male Patients With Gout by Comprehensive Analysis.
Frontiers in immunology
Front Immunol
12
null
10.3389/fimmu.2021.798719
eng
2,021
null
null
2,022
1
18
[OBJECTIVE] Gout is a local inflammatory disease caused by the deposition of monosodium urate (MSU) crystals in joints or adjacent tissues. When some gout occurs without hyperuricemia, or its clinical symptoms and signs are not typical, the diagnosis of gout will be delayed, so there is an urgent need to find a new bio...
biomarker; comprehensive analysis; gout; inflammation; pro-ADM
2.331
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,021
35,115,887
Seroprevalence of Hepatitis B Virus Infection and Its Associated Factors Among Blood Donors in Yemen.
The Malaysian journal of medical sciences : MJMS
Malays J Med Sci
28
5
10.21315/mjms2021.28.5.5
eng
2,021
10
null
2,021
10
26
[BACKGROUND] In limited-resource countries, the prevalence of hepatitis B virus (HBV) infection can be measured using data taken from blood donors. This study aimed to determine the HBV infection seroprevalence and its associated factors among blood donors in Sana'a Governorate, Yemen. [METHODS] A cross-sectional study...
Yemen; blood donors; hepatitis B virus; prevalence
0.433
42
Medicine
Medicine
2,021
35,115,851
The Influence of Personality and Demographic Characteristics on Aggressive Driving Behaviors in Eastern Chinese Drivers.
Psychology research and behavior management
Psychol Res Behav Manag
15
null
10.2147/PRBM.S323431
eng
2,022
null
null
2,022
1
26
[PURPOSE] Road safety research is important due to the large number of road traffic fatalities globally. This study investigated the influences of age, driving experience and other covariates on aggressive driving behavior. [METHODS] A cross-sectional survey was conducted in Yixing City, Wuxi City, Jiangsu Province, Ch...
age; aggressive driving behavior; depressive symptoms; driving experience; neuroticism
0.92
56
Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
35,115,773
Nanobubble Ozone Stored in Hyaluronic Acid Decorated Liposomes: Antibacterial, Anti-SARS-CoV-2 Effect and Biocompatibility Tests.
International journal of nanomedicine
Int J Nanomedicine
17
null
10.2147/IJN.S328090
eng
2,022
null
null
2,022
1
25
[PURPOSE] SARS-CoV-2-infected individuals may be asymptomatic, and therefore, the virus is highly contagious. We aimed to develop an agent to control viral replication in the upper respiratory tract and to prevent progression of the disease into the lower airways as well as inter-individual transmission. For this purpo...
anti-microbial; anti-viral; hyaluronic acid; liposome; nanobubble; ozone
1.111
193
Bioengineering; Biomaterials; Biophysics; Drug Discovery; Medicine; Organic Chemistry; Pharmaceutical Science; Nanoscience and Nanotechnology
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Materials Science; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,115,393
Effect of intravenous thrombolysis before endovascular therapy on outcome according to collateral status: insight from the ETIS Registry.
Journal of neurointerventional surgery
J Neurointerv Surg
15
1
10.1136/neurintsurg-2021-018170
eng
2,023
1
null
2,022
2
3
[BACKGROUND] It is unknown whether collateral status modifies the effect of pretreatment intravenous thrombolysis (IVT) on the outcomes of patients with large vessel occlusions treated with endovascular therapy (EVT). We aimed to assess whether collateral status modifies the effect of IVT on the outcomes of EVT in clin...
stroke; thrombectomy; thrombolysis
1.659
90
Medicine; Neurology; Surgery
Medicine
2,023
35,115,219
The psychological effects of COVID-19-related containment in children: The E-COCCON French study.
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
Arch Pediatr
29
3
10.1016/j.arcped.2022.01.011
eng
2,022
4
null
2,022
1
19
[UNLABELLED] The first containment of the Sars-Cov2 pandemic had the potential to generate posttraumatic stress (PTS) symptoms in children. [OBJECTIVE] The main objective of the study was to determine the prevalence of PTS symptoms within 6 weeks of the end of lockdown, in children contained between March 17, 2020 and ...
COVID-19; Children; Containment; Lockdown; Posttraumatic stress syndrome
0.458
43
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,114,991
Validity and reliability of the spiritual care competency scale for oncology nurses in Taiwan.
BMC palliative care
BMC Palliat Care
21
1
10.1186/s12904-022-00903-w
eng
2,022
2
4
2,022
2
4
[BACKGROUND] Nurses must have spiritual competence to provide holistic patient care. Therefore, the designed instrument to assess nurses' competence could be a practical guide for health care professionals. This study aimed to evaluate the validity and reliability of the spiritual care competency scale (SCCS) for oncol...
Nursing staff; Reproducibility of results; Spirituality
0.907
62
Medicine
Medicine
2,022
35,114,968
Effects of different integrase strand transfer inhibitors on body weight in patients with HIV/AIDS: a network meta-analysis.
BMC infectious diseases
BMC Infect Dis
22
1
10.1186/s12879-022-07091-1
eng
2,022
2
3
2,022
2
3
[BACKGROUND] Global antiretroviral therapy has entered a new era. Integrase strand transfer inhibitor (INSTI) has become the first choice in acquired immunodeficiency syndrome (AIDS) treatment. Because INSTI has high antiviral efficacy, rapid virus inhibition, and good tolerance. However, INSTIs may increase the risk o...
Body weight; HIV/AIDS; Integrase inhibitors; Network meta-analysis
1.055
137
Infectious Diseases
Medicine
2,022
35,114,951
Spatio-temporal variation of bacterioplankton community structure in the Pearl River: impacts of artificial fishery habitat and physicochemical factors.
BMC ecology and evolution
BMC Ecol Evol
22
1
10.1186/s12862-022-01965-3
eng
2,022
2
3
2,022
2
3
[BACKGROUND] Artificial fishery habitat has been widely used in fishery resource protection and water habitat restoration. Although the bacterioplankton plays an important ecological role in fisheries ecosystems, the effect of artificial fishery habitat on bacterioplankton is not clear. In this study, high-throughput s...
Artificial fishery habitat; Bacterial diversity; Bacterioplankton community; Microbial ecology; Pearl River
null
null
null
null
null
35,114,940
Needs of family members caring for stroke survivors in china: A deductive qualitative content analysis study by using the caregiver task inventory-25.
BMC geriatrics
BMC Geriatr
22
1
10.1186/s12877-022-02774-5
eng
2,022
2
3
2,022
2
3
[BACKGROUND] In China, family caregivers are usually the main carers of relatives after stroke due to traditional Chinese culture and the limited development of the primary healthcare system. This responsibility often results in burdens and negative health outcomes. However, family caregivers seldom receive support. To...
Deductive content qualitative analysis; Family caregiver; Needs; Stroke
1.127
112
Geriatrics and Gerontology
Medicine
2,022
35,114,671
Additive Value of a Face-to-Face Visit to Virtual Remote Decision in Patients with Neovascular Age-Related Macular Degeneration.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
Ophthalmologica
245
4
10.1159/000522273
eng
2,022
null
null
2,022
2
3
[INTRODUCTION] The increasing high prevalence of neovascular age-related macular degeneration (nvAMD) in the aging population combined with the need for frequent monitoring and treatment for many years, especially in the COVID-19 era, raises the need to establish an effective, reliable, and safe follow-up and treatment...
Age-related macular degeneration; Management; Ophthalmology; Optical coherence tomography; Telemedicine; Virtual evaluation
null
null
null
null
null
35,114,500
Sex hormones and sperm parameters after adjuvant oxaliplatin-based treatment for colorectal cancer.
Cancer treatment and research communications
Cancer Treat Res Commun
31
null
10.1016/j.ctarc.2022.100517
eng
2,022
null
null
2,022
1
20
[BACKGROUND] The incidence of colorectal cancer (CRC) in individuals of fertile age is increasing. Oxaliplatin is a cornerstone treatment in the adjuvant setting for stage III and high-risk stage II CRC. Limited data exist on possible side effects of oxaliplatin on fertility and gonadal function. More data is needed to...
Chemotherapy; Colorectal cancer; Fertility; Oxaliplatin; Sperm function
0.674
29
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,114,289
Development of a Bowel Management Scoring Tool in Pediatric Patients with Constipation.
The Journal of pediatrics
J Pediatr
244
null
10.1016/j.jpeds.2022.01.036
eng
2,022
5
null
2,022
2
1
[OBJECTIVE] To develop a reliable and valid scoring tool, the Pediatric Bowel Management Scoring Tool (PBMST), to better guide management of constipation in pediatric patients. [STUDY DESIGN] The project comprised 2 stages, development of the questionnaire and construction of the bowel management score. Two questionnai...
bowel management; children; constipation
1.043
246
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,114,165
Scoping Review of Microaggression as an Experience of Racism and Perinatal Health Outcomes.
Journal of obstetric, gynecologic, and neonatal nursing : JOGNN
J Obstet Gynecol Neonatal Nurs
51
2
10.1016/j.jogn.2021.12.007
eng
2,022
3
null
2,022
1
31
[OBJECTIVE] To synthesize current knowledge and identify gaps in the literature related to microaggression as an experience of racism and its influence on perinatal health outcomes. [DATA SOURCES] We searched PubMed, Race Relations Abstracts, Academic Search Complete, CINAHL, PsycInfo, and Scopus using the keywords "mi...
health outcomes; microaggression; obstetrics; perinatal
null
null
null
null
null
35,113,736
Analysis of Hematology and Oncology Fellowship Website Content and Diversity Representation.
JCO oncology practice
JCO Oncol Pract
18
4
10.1200/OP.21.00623
eng
2,022
4
null
2,022
2
3
[PURPOSE] Hematology and oncology (HO) lags behind all medicine subspecialties in fellows under-represented in medicine (URM) despite a growing minority patient population. Websites have been effectively used in URM recruitment. We evaluated all US HO program websites to facilitate a more informed and URM-considerate r...
null
1.349
85
Health Policy; Oncology; Oncology
Medicine; Nursing
2,022
35,113,194
Circulating trimethylamine N-oxide levels following fish or seafood consumption.
European journal of nutrition
Eur J Nutr
61
5
10.1007/s00394-022-02803-4
eng
2,022
8
null
2,022
2
3
[PURPOSE] Some species of fish and seafood are high in trimethylamine N-oxide (TMAO), which accumulates in muscle where it protects against pressure and cold. Trimethylamine (TMA), the metabolic precursor to TMAO, is formed in fish during bacterial spoilage. Fish intake is promoted for its potential cardioprotective ef...
Cardiovascular disease risk; Fish consumption; Gut microbiome; Thrombosis; Trimethylamine N-oxide
1.094
125
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
35,112,645
A multicenter cohort analysis of fractures in histamine-2-receptor antagonist treated pediatric patients.
Current medical research and opinion
Curr Med Res Opin
38
4
10.1080/03007995.2022.2037847
eng
2,022
4
null
2,022
2
25
[BACKGROUND] Histamine 2 receptor antagonists (H2RA) are amongst the most entrenched antacid therapies available including over-the-counter. They have an excellent safety profile including no known teratogenic risk. Fracture risk is generally recognized with chronic proton pump inhibitor (PPI) therapy in adults and chi...
Adverse effects; Bone/epidemiology; Fractures; Gastroesophageal Reflux/drug therapy; Histamine H2 Antagonists/therapeutic use; Retrospective Studies United States/epidemiology; acid-suppression; peptic ulcer disease therapy
0.643
125
Medicine
Medicine
2,022
35,112,612
SARS-COV-2 Screening of Health Care Workers in Brunei Darussalam.
Workplace health safety
Workplace Health Saf
70
10
10.1177/21650799211062802
eng
2,022
10
null
2,022
2
3
[BACKGROUND] Health care workers (HCWs) are at high risk of COVID-19 infection; therefore, screening is recommended for early detection and management to break the chain of transmission. Globally, multiple strategies have been utilized for the screening of HCWs. This article reports and evaluates an active surveillance...
COVID-19; health care worker; risk assessment; screening; surveillance
null
null
null
null
null
35,112,520
Comparison of pramipexole versus ropinirole in the treatment of Parkinson's disease.
Ideggyogyaszati szemle
Ideggyogy Sz
75
1-02
10.18071/isz.75.0039
eng
2,022
1
30
null
null
null
[BACKGROUND AND PURPOSE] Parkinson's disease is a progressive neurodegenerative disease characterized by motor and non-motor symptoms. Levodopa is the most effective drug in the symptomatic treatment of the disease. Dopamine receptor agonists provide sustained dopamin-ergic stimulation and have been found to delay the ...
depression; levodopa; pramipexole; ropinirole
null
null
null
null
null
35,112,417
Scoring of medial arterial calcification predicts cardiovascular events and mortality after kidney transplantation.
Journal of internal medicine
J Intern Med
291
6
10.1111/joim.13459
eng
2,022
6
null
2,022
2
11
[BACKGROUND] Progression of vascular calcification causes cardiovascular disease, which is the most common cause of death in chronic kidney failure and after kidney transplantation (KT). The prognostic impact of the extent of medial vascular calcification at KT is unknown. [METHODS] In this prospective cohort study, we...
cardiovascular events; coronary artery calcification; kidney failure; medial calcification; mortality
2.992
195
Internal Medicine
Medicine
2,022
35,112,181
Thromboprophylaxis after knee arthroscopy does not decrease the risk of deep vein thrombosis: a network meta-analysis.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Knee Surg Sports Traumatol Arthrosc
30
7
10.1007/s00167-021-06857-5
eng
2,022
7
null
2,022
2
3
[PURPOSE] The primary aim of this network meta-analysis (NMA) is to compare the incidence of venous thromboembolisms (VTE) and bleeding risk following the use of pharmacological and non-pharmacological thromboprophylaxis for arthroscopic knee surgery (AKS). This study assumed the null hypothesis which was that there wi...
Arthroscopic knee surgery; Deep vein thrombosis; LMWH; Low molecular weight heparin; Rivaroxaban; Thromboprophylaxis
1.789
160
Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,022
35,112,095
HbA1c, Coronary atheroma progression and cardiovascular outcomes.
American journal of preventive cardiology
Am J Prev Cardiol
9
null
10.1016/j.ajpc.2022.100317
eng
2,022
3
null
2,022
1
18
[BACKGROUND AND AIMS] We tested the hypothesis that on-treatment HbA1c levels independently associate with coronary atheroma progression and major adverse cardiovascular events (MACE: death, myocardial infarction, cerebrovascular accident, coronary revascularization, or hospitalization for unstable angina) rates. [METH...
ACS, acute coronary syndrome; ASCVD, atherosclerotic cardiovascular disease; BMI, body mass index; CVD, cardiovascular disease; Coronary atheroma progression; Diabetes mellitus; HDL-C, high-density lipoprotein cholesterol; HbA1c; HbA1c, hemoglobin A1c; IVUS; IVUS, intravascular ultrasonography; LDL-C, lipoprotein chole...
null
24
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,112,029
Bilateral visual loss, behavioral changes, and overlooking in a young child with stargardt disease: Neurodiagnostic considerations.
American journal of ophthalmology case reports
Am J Ophthalmol Case Rep
25
null
10.1016/j.ajoc.2022.101307
eng
2,022
3
null
2,022
1
21
[PURPOSE] To illustrate the potential diagnostic confusion between Batten disease and Stargardt disease created by associated signs and symptoms. [OBSERVATIONS] A six-year-old girl with vision loss and prominent behavioral changes and overlooking was presumptively diagnosed as having the Batten disease form of neuronal...
Batten; Behavioral changes; Overlooking; Stargardt
null
null
null
null
null
35,111,849
Preliminary Study of Gastroprotective Effect of Aloe perryi and Date Palm Extracts on Pyloric Ligation-Induced Gastric Ulcer in Experimental Rats.
BioMed research international
Biomed Res Int
2022
null
10.1155/2022/9246785
eng
2,022
null
null
2,022
1
24
[OBJECTIVE] The present study was aimed at investigating the possible antiulcer activities of some natural phytochemicals Aloe perryi leaf extract (APLE) and flower extract (APFE) in addition to the date palm seed extract (DPSE) and the oily samples of DPSE in a pylorus ligation-induced ulcer model using ranitidine as ...
null
0.64
203
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,022
35,111,781
Prognosis of Patients With Colorectal Cancer and Apical Lymph Node Metastasis at the Inferior Mesenteric Artery: A Systematic Review and Meta-Analysis.
Frontiers in medicine
Front Med (Lausanne)
8
null
10.3389/fmed.2021.800717
eng
2,021
null
null
2,022
1
17
[BACKGROUND] This review was designed to compile the evidence on the prognosis of patients with colorectal cancer and apical lymph node (APN) metastasis and the long-term benefit of inferior mesenteric artery lymph node (IMA-LN) resection. [METHODS] We searched the PubMed Central, Cochrane library, EMBASE, and MEDLINE ...
apical lymph node; apical lymph node metastasis; meta-analysis; metastasis; overall survival
1.179
102
Medicine
Medicine
2,021
35,111,780
Safety and Efficacy of Tenofovir Alafenamide Fumarate in Early-Middle Pregnancy for Mothers With Chronic Hepatitis B.
Frontiers in medicine
Front Med (Lausanne)
8
null
10.3389/fmed.2021.796901
eng
2,021
null
null
2,022
1
17
[BACKGROUND] Tenofovir alafenamide fumarate has been used in late pregnancy; however, no data exist regarding its safety and effectiveness in early and middle pregnancy for mothers with hepatitis B virus infection. [AIMS] To design a prospective study to investigate the efficacy and safety of TAF in pregnant women with...
chronic hepatitis B; early; mother-to-child transmission; pregnancy; tenofovir alafenamide fumarate
1.179
102
Medicine
Medicine
2,021
35,111,670
Identification and Validation of a Novel Six-lncRNA-Based Prognostic Model for Lung Adenocarcinoma.
Frontiers in oncology
Front Oncol
11
null
10.3389/fonc.2021.775583
eng
2,021
null
null
2,022
1
17
[OBJECTIVE] This study was conducted in order to establish a long non-coding RNA (lncRNA)-based model for predicting overall survival (OS) in patients with lung adenocarcinoma (LUAD). [METHODS] Original RNA-seq data of LUAD samples were extracted from The Cancer Genome Atlas (TCGA) database. Univariate Cox survival ana...
lncRNA; lung adenocarcinoma; overall survival; prognostic model
1.291
156
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,111,642
Impact of waiting time on hepatocellular carcinoma progression in patients undergoing curative tumour ablation.
Quantitative imaging in medicine and surgery
Quant Imaging Med Surg
12
2
10.21037/qims-20-1411
eng
2,022
2
null
null
null
null
[BACKGROUND] A feared consequence to delay in oncological treatment includes disease progression. This study aims to evaluate the relationship between waiting time for ablative therapy in patients with hepatocellular carcinoma (HCC), and the outcomes of local tumour progression, or new HCC foci. [METHODS] Between Janua...
Waiting; carcinoma; hepatocellular; progression; time
0.664
50
Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,111,541
Early functional recovery after two-stage surgery with an allogenic bone graft for baseplate loosening in reverse shoulder arthroplasty: a case report.
Fujita medical journal
Fujita Med J
7
1
10.20407/fmj.2020-002
eng
2,021
null
null
2,020
7
14
[OBJECTIVES] Reverse shoulder arthroplasty (RSA) for cuff tear arthropathy results in good shoulder function. However, RSA is associated with several complications, including infection, dislocation of the shoulder joint, implant loosening, and axillary nerve palsy. Several problems may also occur on the glenoid side, i...
Allogenic bone graft; Baseplate loosening; Reverse shoulder arthroplasty; Two-stage operation
null
2
Health Professions; Medicine
Health Professions; Medicine
2,023
35,111,213
DNA Methylation Biomarkers-Based Human Age Prediction Using Machine Learning.
Computational intelligence and neuroscience
Comput Intell Neurosci
2022
null
10.1155/2022/8393498
eng
2,022
null
null
2,022
1
24
[PURPOSE] Age can be an important clue in uncovering the identity of persons that left biological evidence at crime scenes. With the availability of DNA methylation data, several age prediction models are developed by using statistical and machine learning methods. From epigenetic studies, it has been demonstrated that...
null
null
null
null
null
null
35,110,849
Assessment of Risk Factors for Coronavirus Disease-2019 in Healthcare Workers: A Case-Control Study.
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine
Indian J Crit Care Med
26
1
10.5005/jp-journals-10071-24071
eng
2,022
1
null
null
null
null
[BACKGROUND AND AIMS] With the rise of coronavirus disease-2019 (COVID-19) cases globally, the infection among frontline healthcare workers (HCWs) escalates many folds. There is, however, limited literature from low middle-income countries regarding risk factors for COVID-19 infection in HCWs. We conducted a case-contr...
COVID-19; Healthcare workers; Risk factors
0.439
45
Critical Care and Intensive Care Medicine
Medicine
2,022
35,110,385
Physician judgement in predicting obstructive coronary artery disease and adverse events in chest pain patients.
Heart (British Cardiac Society)
Heart
108
11
10.1136/heartjnl-2021-320275
eng
2,022
5
12
2,022
5
12
[OBJECTIVE] To evaluate informal physician judgement versus pretest probability scores in estimating risk in patients with suspected coronary artery disease (CAD). [METHODS] We included 4533 patients from the PROMISE (Prospective Multicenter Imaging Study for Evaluation of Chest Pain) trial. Physicians categorised a pr...
chest pain; diagnostic imaging; healthcare; outcome assessment
1.877
214
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,110,261
Comparison of the Therapeutic Effects of a Pigtail Catheter and Chest Tube in the Treatment of Spontaneous Pneumothorax: A Randomized Clinical Trial Study.
Turkish thoracic journal
Turk Thorac J
22
6
10.5152/TurkThoracJ.2021.20281
eng
2,021
11
null
null
null
null
[OBJECTIVE] The purpose of this study was to compare the therapeutic effects of a pigtail catheter with a chest tube in the management of patients with spontaneous pneumothorax (SP). [MATERIAL AND METHODS] A randomized controlled trial study was performed on patients with SP from August 2016 to December 2017 at Imam Re...
null
null
null
null
null
null
35,110,198
Comparison of Different Slice Thicknesses on Chest Computed Tomography for Evaluation of COVID-19- Associated Pneumonia.
Turkish thoracic journal
Turk Thorac J
23
1
10.5152/TurkThoracJ.2022.21120
eng
2,022
1
null
null
null
null
[OBJECTIVE] To compare the value of chest computed tomography at 1-mm and 5-mm slice thickness in terms of computed tomography severity score and computed tomography evaluation time in the diagnosis of COVID-19. [MATERIAL AND METHODS] Sixty-five patients were included in the study group who are reverse-transcription po...
null
null
null
null
null
null
35,110,189
Prioritized Commitment-Based Clinical Assessment: A New Method for Assessment of Orthodontic Treatment Outcomes.
Turkish journal of orthodontics
Turk J Orthod
34
3
10.5152/TurkJOrthod.2021.21075
eng
2,021
9
null
null
null
null
[OBJECTIVE] Quality assessment is an essential part of orthodontic treatment. Most of the current indices are essentially based on occlusal assessment. However, an ideal occlusion is only one aspect of an ideal treatment. The aim of this article is to introduce a new prioritized commitment-based clinical assessment (PC...
null
null
null
null
null
null
35,110,026
Effects of calcitonin addition on epidural injection in patients with degenerative spinal canal stenosis: a randomized double blind clinical trial.
Turkish journal of anaesthesiology and reanimation
Turk J Anaesthesiol Reanim
49
6
10.5152/TJAR.2021.1172
eng
2,021
12
null
null
null
null
[OBJECTIVE] Back pain is reported to be the fifth most common reason for referral a patient to a physician and the most common disability in modern society. The present study aimed to evaluate the effects of calcitonin addition on epidural injection in patients with degenerative spinal canal stenosis in comparison with...
null
0.256
20
Anesthesiology and Pain Medicine; Emergency Medicine
Medicine
2,021
35,109,981
Association between endometriosis and lower urinary tract symptoms.
Fertility and sterility
Fertil Steril
117
4
10.1016/j.fertnstert.2022.01.003
eng
2,022
4
null
2,022
1
31
[OBJECTIVE] To determine if women with endometriosis experience lower urinary tract symptoms (LUTSs) more often than those without. [DESIGN] Cross-sectional analysis at enrollment in a longitudinal cohort. [SETTING] Enrollment at 2 academic hospitals and from the local community. [PATIENT(S)] This analysis included 1,1...
Endometriosis; dysuria; lower urinary tract symptoms; stress urinary incontinence
1.579
252
Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,022
35,109,813
Initial and ten-year treatment patterns among 11,000 breast cancer patients undergoing breast surgery-an analysis of German claims data.
BMC cancer
BMC Cancer
22
1
10.1186/s12885-022-09240-w
eng
2,022
2
2
2,022
2
2
[BACKGROUND] We aimed to explore the potential of German claims data for describing initial and long-term treatment patterns of breast cancer patients undergoing surgery. [METHODS] Using the German Pharmacoepidemiological Research Database (GePaRD, ~ 20% of the German population) we included patients with invasive brea...
Breast cancer; Cancer treatment; Claims data; Screening
1.137
171
Genetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,109,809
Soil pH: a key edaphic factor regulating distribution and functions of bacterial community along vertical soil profiles in red soil of pomelo orchard.
BMC microbiology
BMC Microbiol
22
1
10.1186/s12866-022-02452-x
eng
2,022
2
2
2,022
2
2
[BACKGROUND] Soil microbes exist throughout the soil profile and those inhabiting topsoil (0-20 cm) are believed to play a key role in nutrients cycling. However, the majority of the soil microbiology studies have exclusively focused on the distribution of soil microbial communities in the topsoil, and it remains poorl...
Bacterial diversity; Functional analysis; Red soil; Soil pH; Spatial distribution
0.937
147
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,022
35,109,802
MiR-138-5p targets RUNX2 to inhibit osteogenic differentiation of aortic valve interstitial cells via Wnt/β-catenin signaling pathway.
BMC cardiovascular disorders
BMC Cardiovasc Disord
22
1
10.1186/s12872-022-02471-6
eng
2,022
2
2
2,022
2
2
[BACKGROUND] Human aortic valve interstitial cells (hAVICs) are a key factor in the pathogenesis of calcific aortic valve disease (CAVD). This research examines the role and mechanism of microRNA miR-138-5p in osteogenic differentiation of hAVICs. [METHODS] RT-qPCR analysis was applied for detecting miR-138-5p and RUNX...
Aortic valve interstitial cells (AVICs); Calcific aortic valve disease (CAVD); Osteogenic differentiation; RUNX2; miR-138-5p
0.601
76
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,109,694
Association Between Clinical Symptoms, Electrodiagnostic Findings, Clinical Outcome, and Prodromal Symptoms in Patients With Bell's Palsy.
The Annals of otology, rhinology, and laryngology
Ann Otol Rhinol Laryngol
132
1
10.1177/00034894221075107
eng
2,023
1
null
2,022
2
3
[OBJECTIVE] This study aimed to determine which prodromal symptoms frequently occur in patients with Bell's palsy and evaluate the association between these symptoms and clinical severity of paresis or the severity of facial nerve injury. [MATERIALS AND METHODS] The study included 86 patients with Bell's palsy between ...
House-Brackmann grading scale; electrodiagnosis; facial nerve; prodromal symptoms
0.615
107
Medicine; Otorhinolaryngology
Medicine
2,023
35,108,253
Cardiovascular risk factors associated with coronary ectasia and acute myocardial infarction.
Gaceta medica de Mexico
Gac Med Mex
157
6
10.24875/GMM.M21000624
eng
2,021
null
null
null
null
null
[INTRODUCTION] Coronary ectasia has a low prevalence in the general population. Its risk factors may differ from those of coronary artery disease. [OBJECTIVE] To identify the prevalence of coronary ectasia in patients with acute myocardial infarction (AMI) and cardiovascular risk factors (CVRFs). [METHODS] Retrospectiv...
Angiography; Coronary artery disease; Enfermedad coronaria; Herbicidas; Herbicides; Infarto de miocardio; Myocardial infarction; Prevalence; Prevalencia
null
null
null
null
null
35,108,170
Incidence and risk factors of pneumonia following acute traumatic cervical spinal cord Injury.
The journal of spinal cord medicine
J Spinal Cord Med
46
5
10.1080/10790268.2022.2027323
eng
2,023
9
null
2,022
2
2
[OBJECTIVES] To elucidate the incidence and risk factors for pneumonia after acute traumatic cervical spinal cord injury (CSCI). [DESIGN] Retrospective cohort study.Setting: Spinal injuries center in Japan.Participants: Of 184 individuals who were admitted within 2 weeks after acute traumatic cervical spinal injuries, ...
Cervical spinal cord injury; Dysphagia; Paralysis; Pneumonia
0.534
81
Neurology
Medicine
2,023
35,107,167
Clinical efficacy of alternative TNF inhibitor and secukinumab between primary non-responder and secondary non-responder of prior TNF inhibitor in ankylosing spondylitis.
Modern rheumatology
Mod Rheumatol
33
1
10.1093/mr/roac005
eng
2,023
1
3
null
null
null
[OBJECTIVES] To compare the drug retention times and clinical efficacy of alternative tumour necrosis factor inhibitors (TNFi) and secukinumab in primary and secondary non-responders with ankylosing spondylitis (AS). [METHODS] AS patients treated with biologics and enrolled in the Korean College of Rheumatology Biologi...
Ankylosing spondylitis; efficacy; non-responder; secukinumab; tumour necrosis factor inhibitor
0.727
71
Medicine; Rheumatology
Medicine
2,023
35,107,030
Narrative medicine: feasibility of a digital narrative diary application in oncology.
The Journal of international medical research
J Int Med Res
50
2
10.1177/03000605211045507
eng
2,022
2
null
null
null
null
[OBJECTIVES] We implemented narrative medicine in clinical practice using the Digital Narrative Medicine (DNM) platform. [METHODS] We conducted a preliminary, open, uncontrolled, real-life study in the oncology and radiotherapy departments of Istituto di Ricovero e Cura a Carattere Scientifico National Cancer Institute...
Narrative-based medicine; chemotherapy; digital diary; digital narrative medicine; personalized care; personalized medicine; radiotherapy
0.393
74
Biochemistry; Biochemistry; Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,106,574
Serum Vitamin D Levels and Life-Threatening Respiratory Syncytial Virus Infection in Previously Healthy Infants.
The Journal of infectious diseases
J Infect Dis
226
6
10.1093/infdis/jiac033
eng
2,022
9
21
null
null
null
[BACKGROUND] 25-hydroxyvitamin D (VD) effects on lung function and immune-modulation might affect respiratory syncytial virus (RSV) infection outcomes. We aimed to assess VD levels on admission and their association with life-threatening RSV disease (LTD). [METHODS] A prospective cohort study was conducted during 2017-...
25-hydroxyvitamin D; acute respiratory infection; bronchiolitis; intensive care; respiratory syncytial virus; severity
2.386
282
Immunology and Allergy; Infectious Diseases
Medicine
2,022
35,106,119
Octogenarian Motor Vehicle Collisions: Injury Patterns Matter.
Kansas journal of medicine
Kans J Med
15
1
10.17161/kjm.vol15.15710
eng
2,022
null
null
2,022
1
11
[INTRODUCTION] Motor vehicle collision (MVC) is the second most common mechanism of injury among octogenarians and is on the rise. These "oldest old" trauma patients have higher mortality rates than expected. This study examined potential factors influencing this increased mortality including comorbidities, medications...
comorbidity; mortality; octogenarian; polypharmacy; traffic accidents
null
null
null
null
null
35,105,351
The Aβ1-42/Aβ1-40 ratio in CSF is more strongly associated to tau markers and clinical progression than Aβ1-42 alone.
Alzheimer's research therapy
Alzheimers Res Ther
14
1
10.1186/s13195-022-00967-z
eng
2,022
2
1
2,022
2
1
[BACKGROUND] Cerebrospinal fluid (CSF) Aβ1-42 levels and the Aβ1-42/Aβ1-40 ratio are markers of amyloid pathology, but previous studies suggest that their levels might be influenced by additional pathophysiological processes. [AIMS] To compare Aβ1-42 and the Aβ1-42/Aβ1-40 ratio in CSF in different neurodegenerative dis...
Amyloid; Biomarkers; Cerebrospinal fluid; Tau
null
null
null
null
null
35,105,349
Cut-out risk factor analysis after intramedullary nailing for the treatment of extracapsular fractures of the proximal femur: a retrospective study.
BMC musculoskeletal disorders
BMC Musculoskelet Disord
23
1
10.1186/s12891-022-05054-w
eng
2,022
2
1
2,022
2
1
[BACKGROUNDS] The basic method of surgical treatment for extracapsular hip fractures (ECFs), including intertrochanteric fracture and basicervical fracture (BCF), is osteosynthesis. Intramedullary nails are among the most commonly used fixation devices for these fractures. Our study aimed to report the clinical outcome...
Basicervical femoral neck fracture; Complication; Intertrochanteric fracture; Intramedullary nail cut-out
0.716
131
Orthopedics and Sports Medicine; Rheumatology
Medicine
2,022
35,105,273
Estimation of neonatal body fat percentage predicts neonatal hypothermia better than birthweight centile.
The journal of maternal-fetal neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
J Matern Fetal Neonatal Med
35
25
10.1080/14767058.2022.2032634
eng
2,022
12
null
2,022
2
1
[INTRODUCTION] PEA POD™ air displacement plethysmography quickly and noninvasively estimates neonatal body fat percentage (BF%). Low PEA POD™ BF% predicts morbidity better than classification as small-for-gestational-age (SGA; 10th centile), but PEA PODs are not widely available. We examined whether skinfold measuremen...
Air displacement plethysmography; fetal growth restriction; hypothermia; neonatal morbidity; neonatal skinfolds
null
null
null
null
null
35,104,684
A machine learning strategy for fast prediction of cardiac function based on peripheral pulse wave.
Computer methods and programs in biomedicine
Comput Methods Programs Biomed
216
null
10.1016/j.cmpb.2022.106664
eng
2,022
4
null
2,022
1
29
[OBJECTIVE] Pulse wave has been considered as a message carrier in the cardiovascular system (CVS), capable of inferring CVS conditions while diagnosing cardiovascular diseases (CVDs). Clarification and prediction of cardiovascular function by means of powerful feature-abstraction capability of machine learning method ...
Cardiovascular disease (CVD); Cardiovascular function; Machine learning; Pulse wave
1.118
150
Computer Science Applications; Health Informatics; Software
Computer Science; Medicine
2,022
35,104,626
Radial tears in the anterior third of the lateral meniscus are frequently combined with horizontal tears.
Orthopaedics traumatology, surgery research : OTSR
Orthop Traumatol Surg Res
108
3
10.1016/j.otsr.2022.103223
eng
2,022
5
null
2,022
1
31
[INTRODUCTION] Radial tears of the lateral meniscus are often located in the junction of the middle and posterior third or posterior tibial attachment. However, we observed that a few cases of radial tears occurred in the anterior third of the lateral meniscus, and in many cases, they were accompanied by horizontal tea...
Complex tear; Horizontal tear; Lateral meniscus; Radial tear
null
null
null
null
null