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35,103,905
Acceptability of Locally Produced Ready to Use Therapeutic Food (RUTF) in Malnourished Children: A Randomized, Double-Blind, Crossover Study.
Indian journal of pediatrics
Indian J Pediatr
89
11
10.1007/s12098-022-04079-2
eng
2,022
11
null
2,022
2
1
[OBJECTIVE] To compare the acceptability of a locally produced ready-to-use therapeutic food (L-RUTF) with the standard ready-to-use therapeutic food (S-RUTF). [METHODS] It was a single-center, randomized, double-blind, two-way crossover study. The participants were 6-59-mo-old children residing in an urban slum, with ...
Acceptability; Moderate acute malnutrition; Ready-to-use therapeutic food; Severe acute malnutrition; Under five
0.613
67
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,103,439
Empirical analysis of medical malpractice litigation involving urgent-care settings in the Spanish national health service.
Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias
Emergencias
34
1
10.55633/s3me/E105.2022
eng
2,022
2
null
null
null
null
[OBJECTIVES] To analyze the characteristics of superior court decisions in litigation or administrative procedures for medical malpractice claims involving urgent care settings in the Spanish national health service. [MATERIAL AND METHODS] Observational cross-sectional study of judicial rulings handed down between 2008...
Defensive medicine.; Emergency medicine.; Judicial sentences.; Medical liability.; Medicina de urgencias.; Medicina defensiva.; Sentencias.
null
null
null
null
null
35,103,408
Crosswalk between the Mini-Mental State Examination and the Telephone Interview for Cognitive Status (TICS-27/30/40).
Alzheimer's dementia : the journal of the Alzheimer's Association
Alzheimers Dement
18
11
10.1002/alz.12569
eng
2,022
11
null
2,022
2
1
[BACKGROUND] We develop a crosswalk between the Mini-Mental State Examination (MMSE) and Telephone Interview for Cognitive Status (TICS)-27, TICS-30, and TICS-40 for adults 65 years and older. [METHODS] We examined the scores of 1809 participants, with and without cognitive impairment, who completed the MMSE and the TI...
Alzheimer's disease; Telephone Interview for Cognitive Status; crosswalk; dementia, Mini-Mental State Examination
null
null
null
null
null
35,102,781
Subchronic PCP effects on DNA methylation and protein expression of NMDA receptor subunit genes in the prefrontal cortex and hippocampus of female rats.
Journal of psychopharmacology (Oxford, England)
J Psychopharmacol
36
2
10.1177/02698811211069109
eng
2,022
2
null
2,022
2
1
[BACKGROUND] N-methyl-d-aspartate receptor (NMDAR) dysfunction is implicated in schizophrenia, and NMDAR antagonists, such as phencyclidine (PCP), can induce behaviours that mimic aspects of the disorder. [AIMS] We investigated DNA methylation of Grin1, Grin2a and Grin2b promoter region and NR1 and NR2 protein expressi...
DNA methylation; NMDAR antagonist; phencyclidine; protein expression; schizophrenia
1.12
143
Medicine; Pharmacology; Pharmacology; Psychiatry and Mental Health
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,102,764
Attachment orientation and depression: A moderated mediation model of self-silencing and gender differences.
The International journal of social psychiatry
Int J Soc Psychiatry
69
1
10.1177/00207640221074919
eng
2,023
2
null
2,022
2
1
[BACKGROUND] While the effect of insecure attachment on depression is well established, findings pertaining to the relationship between specific attachment dimensions (anxious and avoidant) and depression are inconsistent. The role of interpersonal factors underlying this effect has been little explored. 'Silencing the...
Attachment theory; depression; self-silencing
1.649
86
Medicine; Psychiatry and Mental Health
Medicine
2,023
35,102,516
Adverse Events with D-penicillamine Therapy in Hepatic Wilson's Disease: A Single-Center Retrospective Audit.
Clinical drug investigation
Clin Drug Investig
42
2
10.1007/s40261-022-01117-x
eng
2,022
2
null
2,022
1
31
[UNLABELLED] BACKGROUND AND OBJECTIVE: There are limited data on the adverse events of D-penicillamine in Wilson's disease (WD) that can result in dose modification or treatment discontinuation. The objective of this study was to observe the adverse events related to D-penicillamine in patients with hepatic WD. [METHOD...
null
null
null
null
null
null
35,102,440
A 3-year prospective randomized clinical trial of alveolar bone crest response and clinical parameters through 1, 2, and 3 years of clinical function of implants placed 4 months after alveolar ridge preservation using two different allogeneic bone-grafting materials.
International journal of implant dentistry
Int J Implant Dent
8
1
10.1186/s40729-022-00402-w
eng
2,022
2
1
2,022
2
1
[PURPOSE] The aim of this study was to longitudinally evaluate changes in alveolar bone crest (ABC) levels and differences in resorption rates (RR) between the tested grafting materials following alveolar ridge preservation (ARP) after tooth extraction after 1, 2, and 3 years (T1-T8) of clinical function. [METHODS] Pat...
Allogeneic bone graft; Alveolar ridge preservation; Extraction socket; Implants; PRGF; Pericardium membrane
null
4
Medicine
Medicine
2,022
35,102,397
Sex Differences Distinctly Impact High-Fat Diet-Induced Immune Dysfunction in Wistar Rats.
The Journal of nutrition
J Nutr
152
5
10.1093/jn/nxac024
eng
2,022
5
5
null
null
null
[BACKGROUND] Immune function is altered during obesity. Moreover, males and females across different species demonstrate distinct susceptibility to several diseases. However, less is known regarding the interplay between high-fat diet (HFD) and sex in the context of immune function. [OBJECTIVES] The objective was to de...
cytokines; high-fat diet; immune function; obesity; sex differences
1.125
306
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
35,102,117
Electrical Stimulation-Mediated Tissue Healing in Porcine Intervertebral Disc Under Mechanically Dynamic Organ Culture Conditions.
Spine
Spine (Phila Pa 1976)
47
10
10.1097/BRS.0000000000004331
eng
2,022
5
15
2,022
1
31
[STUDY DESIGN] Porcine intervertebral discs (IVDs) were excised and then drilled to simulate degeneration before being electrically stimulated for 21 days while undergoing mechanical loading. The discs were then analyzed for gene expression and morphology to assess regeneration. [OBJECTIVE] The purpose of this study wa...
null
1.197
300
Neurology; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,022
35,101,946
TSH-TSHR axis promotes tumor immune evasion.
Journal for immunotherapy of cancer
J Immunother Cancer
10
1
10.1136/jitc-2021-004049
eng
2,022
1
null
null
null
null
[BACKGROUND] Hormones are identified as key biological variables in tumor immunity. However, previous researches mainly focused on the immune effect of steroid hormones, while the roles that thyroid-stimulating hormone (TSH) played in the antitumor response were far from clear. [METHODS] The source of TSH was determine...
brain neoplasms; immune evation; immunotherapy; tumor microenvironment
3.403
136
Cancer Research; Immunology; Immunology and Allergy; Molecular Medicine; Oncology; Pharmacology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,101,406
A comparative study of pathogen inactivation technologies in human platelet lysate and its optimal efficiency in human placenta-derived stem cells culture.
Journal of virological methods
J Virol Methods
302
null
10.1016/j.jviromet.2022.114478
eng
2,022
4
null
2,022
1
29
[BACKGROUND] Pathogen inactivation (PI) is necessary for the pooled components derived from a biological source. Recently, the use of human platelet lysate (hPL) has increased in the cell manufacturing process as a xeno-free substitute for Fetal Bovine Serum (FBS). Therefore, an effective PI process to produce a pathog...
Cell therapy; Gamma irradiation; Mesenchymal stem cells; Pathogen inactivation; Platelet lysate; Ultraviolet
0.634
119
Virology
Immunology and Microbiology
2,022
35,101,356
Prevalence and risk factors associated with chronic kidney disease in Moroccan rural communes: Fez-Meknes region.
Nephrologie therapeutique
Nephrol Ther
18
2
10.1016/j.nephro.2021.11.005
eng
2,022
4
null
2,022
1
31
[BACKGROUND AND AIMS] Chronic kidney disease is a worldwide public health issue. It can be a serious problem, especially in developing countries including Morocco. However, few studies have explored the factors influencing chronic kidney disease in this country. Hence, using the definitions proposed by Kidney Disease I...
Chronic kidney disease; Epidemiology; Estimated Glomerular filtration rate; Hematuria; Morocco; Proteinuria
null
null
null
null
null
35,101,035
LINC00665 up-regulates SIN3A expression to modulate the progression of colorectal cancer via sponging miR-138-5p.
Cancer cell international
Cancer Cell Int
22
1
10.1186/s12935-021-02176-4
eng
2,022
1
31
2,022
1
31
[BACKGROUND] Colorectal cancer (CRC) is a malignant tumor affecting people worldwide. Long noncoding RNAs (lncRNAs) is a crucial factor modulating various cancer progression, including CRC. Long intergenic non-protein coding RNA 665 (LINC00665) has been proven as an oncogene in several cancers, but its function in CRC ...
Colorectal cancer; LINC00665; SIN3A; miR-138-5p
1.145
90
Genetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,100,978
Repression of lncRNA PART1 attenuates ovarian cancer cell viability, migration and invasion through the miR-503-5p/FOXK1 axis.
BMC cancer
BMC Cancer
22
1
10.1186/s12885-021-09005-x
eng
2,022
1
31
2,022
1
31
[BACKGROUND] Ovarian cancer (OC) is a female malignant tumor with a high fatality rate. Long non-coding RNAs (lncRNAs) are deeply involved in OC progression. The aim of this study is to explore the specific mechanism of lncRNA prostate androgen-regulated transcript 1 (PART1) in OC. [METHODS] Quantitative real time PCR ...
FOXK1; Ovarian cancer; lncRNA PART1; miR-503-5p
1.137
171
Genetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,100,785
Infant Cardiopulmonary Resuscitation Quality While Walking Fast: A Simulation Study.
Pediatric emergency care
Pediatr Emerg Care
38
2
10.1097/PEC.0000000000002505
eng
2,022
2
1
null
null
null
[OBJECTIVE] This study focuses on the characteristics (feasibility, resuscitation quality, and physical demands) of infant cardiopulmonary resuscitation (CPR) on the forearm during fast walking, performed by a trained lay rescuer. [METHODS] Twenty-one university students from the infant education degree participated in...
null
0.404
79
Emergency Medicine; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,022
35,100,742
Is Diffuse Axonal Injury Different in Adults and Children? An Analysis of National Trauma Database.
Pediatric emergency care
Pediatr Emerg Care
38
2
10.1097/PEC.0000000000002626
eng
2,022
2
1
null
null
null
[BACKGROUND] Diffuse axonal injury (DAI) is typically associated with significant mechanisms of injury and the effects of acceleration-deceleration forces on brain tissues. The prognosis of DAI remains a matter of active investigation, but little is known about outcome differences between adult and pediatric population...
null
0.404
79
Emergency Medicine; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,022
35,100,628
A Nurse-Led Voiding Algorithm for Managing Urinary Retention After General Thoracic Surgery.
Critical care nurse
Crit Care Nurse
42
1
10.4037/ccn2022727
eng
2,022
2
1
null
null
null
[BACKGROUND] Untreated postoperative urinary retention (POUR) leads to bladder overdistension. Treatment of POUR involves urinary catheterization, which predisposes patients to catheter-associated urinary tract infections. The hospital's rate of POUR after lobectomy was 21%, exceeding the Society of Thoracic Surgeons' ...
null
0.437
53
Critical Care Nursing; Medicine
Medicine; Nursing
2,022
35,100,616
Evaluation of Female Fertility-AMH and Ovarian Reserve Testing.
The Journal of clinical endocrinology and metabolism
J Clin Endocrinol Metab
107
6
10.1210/clinem/dgac039
eng
2,022
5
17
null
null
null
[CONTEXT] Evaluation of the infertile female requires an understanding of ovulation and biomarkers of ovarian reserve. Antimüllerian hormone (AMH) correlates with growing follicles in a menstrual cycle. Increasingly, AMH has been used as a "fertility test." This narrative review describes how to integrate the use of AM...
AMH; female infertility; ovarian reserve
1.776
400
Biochemistry; Biochemistry; Clinical Biochemistry; Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,099,875
Acceptance, refusal and hesitancy of Covid-19 vaccination in Mexico: Ensanut 2020 Covid-19.
Salud publica de Mexico
Salud Publica Mex
63
5
10.21149/12696
eng
2,021
9
3
2,021
9
3
[OBJECTIVE] To estimate the willingness to vaccinate against Covid-19 (acceptance) in the Mexican population and to iden-tify socioeconomic factors associated with vaccine hesitancy and refusal. [MATERIALS AND METHODS] We estimated the acceptance, refusal and hesitancy proportions using data from the Covid-19 National ...
null
null
null
null
null
null
35,098,600
Exploring correlations between MS and NMR for compound identification using essential oils: A pilot study.
Phytochemical analysis : PCA
Phytochem Anal
33
4
10.1002/pca.3107
eng
2,022
6
null
2,022
1
30
[INTRODUCTION] In this era of 'omics' technology in natural products studies, the complementary aspects of mass spectrometry (MS)- and nuclear magnetic resonance (NMR)-based techniques must be taken into consideration. The advantages of using both analytical platforms are reflected in a higher confidence of results esp...
GC-MS; NMR; STOCSY; compound identification; data fusion; dereplication; essential oils; metabolomics; statistical heterospectroscopy
0.533
88
Complementary and Alternative Medicine; Analytical Chemistry; Drug Discovery; Food Science; Medicine; Plant Science; Biochemistry; Molecular Medicine
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,098,549
Investigation of image quality of MV and kV CBCT with low-Z beams and high DQE detector.
Medical physics
Med Phys
49
4
10.1002/mp.15503
eng
2,022
4
null
2,022
2
16
[PURPOSE] To investigate cone beam computed tomography (CBCT) image quality using novel combinations of kilovoltage (kV) and megavoltage (MV) beams and detector materials. [METHODS] MV and kV CBCT imaging was simulated using the Fastcat hybrid Monte Carlo application. CBCT imaging with various beam energies was investi...
CBCT; low Z target
1.072
218
Biophysics; Medicine; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,098,350
Clinical and structural outcome of intra-articular steroid injection for early stiffness after arthroscopic rotator cuff repair.
International orthopaedics
Int Orthop
46
3
10.1007/s00264-021-05288-8
eng
2,022
3
null
2,022
1
31
[PURPOSE] Direct comparative results of patients with early stiffness after arthroscopic rotator cuff repair (ARCR) with and without steroid injection are still unclear. This study aimed to evaluate the clinical and structural effect of intra-articular steroid injection for early stiffness after ARCR. [METHODS] From 20...
Retear; Rotator cuff repair; Shoulder stiffness; Steroid
0.988
116
Orthopedics and Sports Medicine; Surgery
Medicine
2,022
35,097,473
The Relationship Between the Distal Tibial Fibular Syndesmosis and the Varus Deformity in Patients With Varus Ankle Osteoarthritis.
Foot ankle orthopaedics
Foot Ankle Orthop
6
4
10.1177/24730114211041111
eng
2,021
10
null
2,021
10
26
[BACKGROUND] The impact of varus ankle osteoarthritis (OA) on the distal tibial fibular syndesmosis is poorly described. This study aimed to investigate the possible relationship between the condition of the distal tibial fibular syndesmosis and the degree of the varus deformity using weightbearing simulated computed t...
etiology; syndesmosis; varus ankle osteoarthritis
null
null
null
null
null
35,097,236
Maternal factors associated with smoking during gestation and consequences in newborns: Results of an 18-year study.
Journal of clinical and translational research
J Clin Transl Res
8
1
null
eng
2,022
2
25
2,022
1
3
[BACKGROUND] Tobacco use is one of the most important causes of obstetric and perinatal pathologies. Its frequency during pregnancy is high and could be related to various socioeconomic and cultural characteristics of the mothers. [AIM] The aim of this study is to determine the trend and prevalence of smoking in pregna...
breastfeeding; low birth weight; pregnancy; tobacco
null
null
null
null
null
35,097,168
Effect of Institution and COVID-19 on Access to Adult Arthroplasty Surgery.
Arthroplasty today
Arthroplast Today
14
null
10.1016/j.artd.2022.01.027
eng
2,022
4
null
2,022
1
24
[BACKGROUND] Although insurance status is important to patients' ability to access care, it varies significantly by race, age, and socioeconomic status. Novel coronavirus disease 2019 (COVID-19) negatively impacted access to care, while simultaneously widening pre-existing health-care disparities. The purpose of the pr...
Arthroplasty; COVID; Disparity; Insurance; Safety-net; Wait time
0.808
32
Surgery; Orthopedics and Sports Medicine
Medicine
2,022
35,096,549
Correlation of cardiac troponin T levels with inotrope requirement, hypoxic-ischemic encephalopathy, and survival in asphyxiated neonates.
World journal of clinical pediatrics
World J Clin Pediatr
11
1
10.5409/wjcp.v11.i1.85
eng
2,022
1
9
2,022
1
9
[BACKGROUND] Cardiac involvement in neonates with perinatal asphyxia not only complicates perinatal management but also contributes to increased mortality. [AIM] To assess cardiac troponin T (cTnT) levels in asphyxiated neonates and their correlation with echocardiography findings, inotrope requirement, hypoxic-ischemi...
Asphyxia; Cardiac dysfunction; Inotropes; Neonates; Survival; troponin T
0.378
13
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,096,445
The role of intraoperative pulmonary arterial catheterization data in determining the need for extracorporeal membrane oxygenation in lung transplantation.
Turk gogus kalp damar cerrahisi dergisi
Turk Gogus Kalp Damar Cerrahisi Derg
29
4
10.5606/tgkdc.dergisi.2021.20485
eng
2,021
10
null
2,021
10
20
[BACKGROUND] This study aims to investigate predictive factors of identification of the need of patients for extracorporeal membrane oxygenation support during lung transplantation. [METHODS] A total of 63 patients (49 males, 14 females, mean age: 44.9±14.4 years; range, 14 to 64 years) who underwent lung transplantati...
Extracorporeal membrane oxygenation; lung transplantation; pulmonary artery catheterization; pulmonary hypertension
null
null
null
null
null
35,096,127
The Imbalance Expression of DLX3 May Perform Critical Function in the Occurrence and Progression of Preeclampsia.
Computational and mathematical methods in medicine
Comput Math Methods Med
2022
null
10.1155/2022/1457398
eng
2,022
null
null
2,022
1
21
[BACKGROUND] The present research focuses on preeclampsia (PE), a clinically relevant pregnancy disease. To date, the majority of research on PE was centered on placental insufficiency. However, the genes that regulate these processes, and the exact molecular mechanisms modulating these processes, are still unclear. [M...
null
null
null
null
null
null
35,095,864
Combination of Tertiary Lymphoid Structure and Neutrophil-to-Lymphocyte Ratio Predicts Survival in Patients With Hepatocellular Carcinoma.
Frontiers in immunology
Front Immunol
12
null
10.3389/fimmu.2021.788640
eng
2,021
null
null
2,022
1
13
[BACKGROUND] Hepatocellular carcinoma (HCC) is the most common pathological type of primary liver cancer. The lack of prognosis indicators is one of the challenges in HCC. In this study, we investigated the combination of tertiary lymphoid structure (TLS) and several systemic inflammation parameters as a prognosis indi...
hepatocellular carcinoma; inflammation; neutrophil-to-lymphocyte ratio (NLR); overall survival; tertiary lymphoid structure
2.331
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,021
35,095,848
The Kynurenine/Tryptophan Ratio Is a Sensitive Biomarker for the Diagnosis of Pediatric Tuberculosis Among Indian Children.
Frontiers in immunology
Front Immunol
12
null
10.3389/fimmu.2021.774043
eng
2,021
null
null
2,022
1
12
[OBJECTIVES] Pediatric tuberculosis (TB) remains difficult to diagnose. The plasma kynurenine to tryptophan ratio (K/T ratio) is a potential biomarker for TB diagnosis and treatment response but has not been assessed in children. [METHODS] We performed a targeted diagnostic accuracy analysis of four biomarkers: kynuren...
biomarker; diagnostics; metabolomics (OMICS); pediatric tuberculosis; transcriptomics
2.331
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,021
35,095,091
The Prevalence of COVID-19 Vaccination and Vaccine Hesitancy in Pregnant Women: An Internet-based Cross-sectional Study in Japan.
Journal of epidemiology
J Epidemiol
32
4
10.2188/jea.JE20210458
eng
2,022
4
5
2,022
2
11
[BACKGROUND] Reluctance of people to receive recommended vaccines is a growing concern, as distribution of vaccines is considered critical to ending the COVID-19 pandemic. There is little information regarding pregnant women's views toward coronavirus vaccination in Japan. Therefore, we investigated the vaccination rat...
COVID-19; pregnancy; vaccine; vaccine hesitancy
1.157
95
Medicine; Epidemiology
Medicine
2,022
35,095,005
Virtual office intervention effectiveness: A systems approach.
Work (Reading, Mass.)
Work
71
2
10.3233/WOR-210698
eng
2,022
null
null
null
null
null
[BACKGROUND] Virtual office work, or telework/remote work, has existed since the 1970s due to the widespread availability of new technologies. Despite a dramatic increase in remote office work, few studies have examined its long-term effects on work environments and worker well-being. [OBJECTIVE] A prospective field in...
COVID-19; Telework; field study; macroergonomics; prospective design
null
null
null
null
null
35,094,802
Using Virtual Reality Exposure Therapy in Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
Value Health
25
2
10.1016/j.jval.2021.04.1285
eng
2,022
2
null
2,021
10
8
[OBJECTIVES] This study aimed to assess the effectiveness of virtual reality (VR) in managing different types of pain in different age groups and to provide evidence for the clinical application of new alternative strategy for pain management. [METHODS] Electronic databases, including the Cochrane Library, PubMed, EMBA...
meta-analysis; pain; systematic review; virtual reality
1.414
138
Health Policy; Medicine; Public Health, Environmental and Occupational Health
Medicine
2,022
35,094,734
Acceptance and challenges of the introduction of the routine community-based vitamin A supplementation strategy: the case of Burkina Faso.
Public health nutrition
Public Health Nutr
25
5
10.1017/S1368980022000283
eng
2,022
1
31
2,022
1
31
[OBJECTIVES] With the phase-out of the polio campaigns, Burkina Faso has developed a new strategy for routine community-based vitamin A supplementation (VAS) by institutionalising community-based health workers (CBHW) to sustain the gain of two decades of successful programming. Formative research was conducted soon af...
Acceptance; Adoption; Burkina Faso; Challenges; Routine community-based strategy; Vitamin A supplementation (VAS)
0.874
173
Medicine; Nutrition and Dietetics; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,022
35,094,573
The lifetime risk of revision following total knee arthroplasty : a New Zealand Joint Registry study.
The bone joint journal
Bone Joint J
104-B
2
10.1302/0301-620X.104B2.BJJ-2021-0890.R1
eng
2,022
2
null
null
null
null
[AIMS] The success of total knee arthroplasty (TKA) is usually measured using functional outcome scores and revision-free survivorship. However, reporting the lifetime risk of revision may be more meaningful to patients when gauging risks, especially in younger patients. We aimed to assess the lifetime risk of revision...
Anesthesiologists; Arthroplasty; Aseptic loosening; Comorbidities; Functional outcome scores; Infection; Joint registries; Knee; Lifetime risk; Primary TKAs; Revision; Revision risk; Revision surgery; Revision total knee arthroplasty (TKA); Total knee arthroplasty; Total knee arthroplasty (TKA)
null
null
null
null
null
35,094,568
Wear resistance of first-generation highly cross-linked annealed polyethylene in cementless total hip arthroplasty is maintained 20 years after surgery.
The bone joint journal
Bone Joint J
104-B
2
10.1302/0301-620X.104B2.BJJ-2021-1079.R1
eng
2,022
2
null
null
null
null
[AIMS] The aim of this study was to evaluate the performance of first-generation annealed highly cross-linked polyethylene (HXLPE) in cementless total hip arthroplasty (THA). [METHODS] We retrospectively evaluated 29 patients (35 hips) who underwent THA between December 2000 and February 2002. The survival rate was est...
BMI; Body weight; Cementless total hip arthroplasty; Cross-linked; Femoral components; Highly cross-linked polyethylene (HXLPE); Hip joint; Hips; Osteolysis; Polyethylene; Polyethylene wear; Total hip arthroplasty; Wear resistance
null
null
null
null
null
35,094,224
Phacoemulsification with double-in-bag intraocular lens implantation in nanophthalmic eyes with angle-closure glaucoma.
International ophthalmology
Int Ophthalmol
42
6
10.1007/s10792-021-02183-4
eng
2,022
6
null
2,022
1
30
[PURPOSE] To report the outcomes of phacoemulsification with piggyback intraocular lens (IOL) implantation, with double-in-bag IOLs in the management of angle-closure glaucoma (ACG) in nanophthalmic eyes. [METHODS] This is a retrospective case series on nanophthalmic eyes with variable presentations of ACG. Phacoemulsi...
Angle-closure glaucoma; Angle-closure glaucoma in nanophthalmos; Nanophthalmos; Refractive lens exchange in nanophthalmos
0.587
57
Ophthalmology
Medicine
2,022
35,094,111
Non-steroidal anti-inflammatory drugs and acetylsalicylic acid increase the risk of complications of diverticular disease: a meta-analysis of case-control and cohort studies.
International journal of colorectal disease
Int J Colorectal Dis
37
3
10.1007/s00384-021-04088-1
eng
2,022
3
null
2,022
1
30
[BACKGROUND] The role of non-steroidal anti-inflammatory drugs (NSAIDs) and acetylsalicylic acid in the occurrence of diverticular bleeding (DB), complicated diverticulitis (CD), and acute diverticulitis (AD) is not yet defined. [AIM] Update a systematic review and meta-analyses of case-control and cohort studies to ev...
Acetylsalicylic acid; Complicated diverticulitis; Diverticular bleeding; Diverticular disease; Diverticulitis; Non-steroidal anti-inflammatory drugs
0.813
103
Gastroenterology
Medicine
2,022
35,093,907
Spontaneous Chromosomal Aberrations in Lymphocytes and Development of Tumor in Hospital Workers.
Anticancer research
Anticancer Res
42
2
10.21873/anticanres.15567
eng
2,022
2
null
null
null
null
[BACKGROUND] Cytogenetic analysis of chromosomes in blood lymphocytes can be used to reveal biomarkers of tumor risk. The frequency of chromosomal aberrations (CAs) appears to correlate with the later incidence of cancer. [PATIENTS AND METHODS] In our work, a total of 515 healthy Hungarian medical workers and 725 contr...
Cytogenetic analysis; aneuploidy; cancer; chromosome aberrations; medical workers; risk assessment
null
null
null
null
null
35,093,892
Sacral Chordoma: A Population-based Analysis of Epidemiology and Survival Outcomes.
Anticancer research
Anticancer Res
42
2
10.21873/anticanres.15552
eng
2,022
2
null
null
null
null
[BACKGROUND/AIM] Sacral chordoma is a rare primary bone neoplasm associated with high morbidity. The aim of this study is to identify demographic and clinicopathological characteristics of this tumor and evaluate their impact on survival outcomes. [PATIENTS AND METHODS] The Surveillance, Epidemiology and End Results (S...
SEER; Sacral; cancer; chordoma; population; survival
null
null
null
null
null
35,093,647
Development of an automatic modeling method for patient-specific aortic graft reconstruction guide in thoracoabdominal aortic repair.
Computer methods and programs in biomedicine
Comput Methods Programs Biomed
215
null
10.1016/j.cmpb.2022.106647
eng
2,022
3
null
2,022
1
21
[BACKGROUND AND OBJECTIVES] Because repairing visceral and segmental arteries in open surgical repair for thoracoabdominal aortic aneurysms is essential, two types of patient-specific graft reconstruction guides for reconstruction in the operating room have been developed that are applied clinically. However, designing...
Automatic modeling; Computer-aided design; Graft reconstruction; Python-based script program; Thoracoabdominal aortic aneurysm
1.118
150
Computer Science Applications; Health Informatics; Software
Computer Science; Medicine
2,022
35,093,630
MiR-107 Aggravates Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-Induced Injury Through Inactivating PI3K-AKT Signalling Pathway by Targeting FGF9/FGF12 in PC12 Cells.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
31
4
10.1016/j.jstrokecerebrovasdis.2021.106295
eng
2,022
4
null
2,022
1
29
[OBJECTIVES] The aberrant expression of miR-107 has been confirmed in some neurological diseases, including ischemic stroke (IS). However, the function of miR-107 and underlying mechanisms are ambiguous. [MATERIALS AND METHODS] Oxygen-Glucose Deprivation/Reoxygenation (OGD/R)-induced PC12 cells were used to mimic IS co...
Fibroblast growth factor; Ischemia/reperfusion injury; MiR-107; Oxygen-Glucose Deprivation/Reoxygenation; PC12 cells
0.713
85
Rehabilitation; Surgery; Cardiology and Cardiovascular Medicine; Neurology
Medicine
2,022
35,093,160
Long-read metagenomic sequencing reveals shifts in associations of antibiotic resistance genes with mobile genetic elements from sewage to activated sludge.
Microbiome
Microbiome
10
1
10.1186/s40168-021-01216-5
eng
2,022
1
29
2,022
1
29
[BACKGROUND] There is concern that the microbially rich activated sludge environment of wastewater treatment plants (WWTPs) may contribute to the dissemination of antibiotic resistance genes (ARGs). We applied long-read (nanopore) sequencing to profile ARGs and their neighboring genes to illuminate their fate in the ac...
Antibiotic resistance; Long read sequencing; Mobile genetic elements; Plasmid; Resistome; Wastewater; Wastewater treatment
3.709
163
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,022
35,093,091
Informal payments for modern family planning methods at public facilities in Tanzania: room for improvement.
Human resources for health
Hum Resour Health
20
1
10.1186/s12960-022-00712-5
eng
2,022
1
29
2,022
1
29
[BACKGROUND] Financial access to family planning (FP) is essential to the health and well-being of women in Tanzania. Tanzanian policy dictates that FP methods and services obtained at public facilities are provided for free. However, public sector FP is no longer free when providers solicit informal payments. In this ...
Access; Contraception; Family planning; Informal fees; Informal payments; Quality-of-care
1.203
89
Public Administration; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,022
35,093,043
Translation and validation of Chinese version of sense of competence in dementia care staff scale in healthcare providers: a cross-sectional study.
BMC nursing
BMC Nurs
21
1
10.1186/s12912-022-00815-3
eng
2,022
1
30
2,022
1
30
[BACKGROUND] Healthcare providers' dementia-care competence is crucial for quality dementia care. A reliable and valid instrument is needed to assess the gaps in their dementia-care competence, and thereby identifying their educational needs. Therefore, this study aims to translate the 17-item Sense of Competence in De...
Chinese; Dementia; Reliability; Sense of competence; Validity
0.769
62
Nursing
Nursing
2,022
35,093,039
Flu-IV score: a predictive tool for assessing the risk of invasive mechanical ventilation in patients with influenza-related pneumonia.
BMC pulmonary medicine
BMC Pulm Med
22
1
10.1186/s12890-022-01833-2
eng
2,022
1
29
2,022
1
29
[BACKGROUND] The need for invasive mechanical ventilation (IMV) is linked to significant morbidity and mortality in patients with influenza-related pneumonia (Flu-p). We aimed to develop an assessment tool to predict IMV among Flu-p patients within 14 days of admission. [METHODS] In total, 1107 Flu-p patients from five...
Influenza; Invasive mechanical ventilation; Pneumonia; Prediction rule
0.999
85
Pulmonary and Respiratory Medicine
Medicine
2,022
35,117,346
Non-target genetic manipulation induces rhabdomyosarcoma in KrasPten-driven mouse model of ovarian cancer.
Translational cancer research
Transl Cancer Res
9
12
10.21037/tcr-20-2561
eng
2,020
12
null
null
null
null
[BACKGROUND] Genetically engineered mice are ideal models to advance our understanding the tumorigenesis of ovarian cancer. Our original objective was to establish an ovarian cancer model induced by Kras activation and Pten deletion. However, proficiently establishing the model remains a technical problem, which limits...
Kras; Pten; adenovirus leakage; ovarian cancer; rhabdomyosarcoma (RMS)
0.254
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,020
35,117,311
Nomogram for predicting axillary lymph node status after neoadjuvant chemotherapy in breast cancer.
Translational cancer research
Transl Cancer Res
9
11
10.21037/tcr-20-2377
eng
2,020
11
null
null
null
null
[BACKGROUND] Many breast cancer patients benefit from neoadjuvant chemotherapy (NAC). However, sentinel lymph node biopsy (SLNB) after NAC remains controversial, especially for patients with axillary lymph node metastasis (ALNM) at diagnosis. We developed a nomogram for predicting axillary lymph node (ALN) status after...
Breast cancer; neoadjuvant chemotherapy (NAC); nomogram; sentinel lymph node biopsy (SLNB)
0.254
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,020
35,117,292
Tolerance and outcome of hypofractionated post-mastectomy radiotherapy among elderly breast cancer patients in a specialized center in Nigeria.
Translational cancer research
Transl Cancer Res
9
11
10.21037/tcr-20-1335
eng
2,020
11
null
null
null
null
[BACKGROUND] The incidence of breast cancer rises dramatically with age, and numerous studies have reported the benefits of post mastectomy radiotherapy in both young and elderly breast cancer patients. The limited numbers of radiotherapy machines and the conventional fractionation schedule which are of long duration m...
Advanced age; Nigeria; breast cancer patients; hypofractionated radiotherapy; outcome
0.254
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,020
35,117,199
Exosomal prostate-specific G-protein-coupled receptor induces osteoblast activity to promote the osteoblastic metastasis of prostate cancer.
Translational cancer research
Transl Cancer Res
9
10
10.21037/tcr-20-1858
eng
2,020
10
null
null
null
null
[BACKGROUND] Prostate cancer (PCa) is the second leading cause of cancer-related deaths worldwide. Prostate-specific G-protein-coupled receptor (PSGR) has been identified as a new potential biomarker and therapeutic target for PCa. However, the influence of exosomal PSGR on PCa metastasis remains unknown. This study ai...
Prostate cancer (PCa); exosome; mechanism
0.254
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,020
35,117,198
Lymph node ratio predicts prognosis in patients with surgically resected invasive pancreatic cystic neoplasms.
Translational cancer research
Transl Cancer Res
9
10
10.21037/tcr-20-1355
eng
2,020
10
null
null
null
null
[BACKGROUND] In current days, the prevalence of pancreatic cystic neoplasms (PCN) is on the rise. Lymph node ratio (LNR) has emerged as a promising prognostic factor in pancreatic adenocarcinoma (PDAC). However, the prognostic value of LNR in patients with invasive PCN remains unknown. [METHODS] We used Surveillance, E...
Lymph node ratio (LNR); Pancreatic cystic neoplasms (PCNs); SEER database
0.254
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,020
35,117,750
Plantamajoside modulates the proliferation, stemness, and apoptosis of lung carcinoma via restraining p38MAPK and AKT phosphorylation.
Translational cancer research
Transl Cancer Res
9
6
10.21037/tcr-20-1834
eng
2,020
6
null
null
null
null
[BACKGROUND] Plantamajoside (PMS), an active anti-inflammatory component and antioxidant derived from Herba Plantaginis, has been reported to exert a suppressive effect in liver cancer in vivo. In this study, we tested the effects of PMS on the metastatic 95D cell line. [METHODS] 95D cells were characterized as most se...
Lung cancer; mitochondrial membrane potential; oxidative stress
0.254
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,020
35,117,730
Serum levels of microRNA-21 and microRNA-10a can predict long-term prognosis in laryngeal cancer patients: a multicenter study.
Translational cancer research
Transl Cancer Res
9
5
10.21037/tcr-20-1758
eng
2,020
5
null
null
null
null
[BACKGROUND] Laryngeal squamous cell carcinoma (LSCC) ranks as the second most common subtype of squamous cell sarcoma (SCC) of the head and neck. In clinical practice, more tools are required to assist doctors in identifying patients who are at risk of poor prognosis at an early stage. Many studies have shown that mic...
laryngeal cancer; microRNA-10a; microRNA-21
0.254
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,020
35,117,464
Triptonide inhibits metastasis potential of thyroid cancer cells via astrocyte elevated gene-1.
Translational cancer research
Transl Cancer Res
9
2
10.21037/tcr.2019.12.94
eng
2,020
2
null
null
null
null
[BACKGROUND] Triptonide (TN) was recently proved to have anti-tumor effects. The current study explored whether TN inhibited thyroid cancer and the possible underlying mechanism. [METHODS] MDA-T68 and BCPAP cells were treated by TN. Cell viability, migration and invasion rate were detected by MTT and Transwell. Protein...
null
0.254
43
Cancer Research; Oncology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,020
35,111,524
Changes in the characteristics of patients with latex allergy from 1999 to 2014.
Fujita medical journal
Fujita Med J
6
3
10.20407/fmj.2019-013
eng
2,020
null
null
2,020
2
11
[OBJECTIVES] We conducted a multicenter study using the same questionnaire in 1999 and 2014 to investigate changes in the characteristics of patients with latex allergy. [METHODS] We mailed questionnaires on latex allergy to hospitals in Japan that were members of the Japanese Latex Allergy Society. [RESULTS] We compar...
Health care workers; Latex allergy; Type I allergy
null
2
Health Professions; Medicine
Health Professions; Medicine
2,023
35,111,519
Uniportal video-assisted thoracic surgery lowers the incidence of post-thoracotomy pain syndrome.
Fujita medical journal
Fujita Med J
6
2
10.20407/fmj.2019-008
eng
2,020
null
null
2,020
2
11
[OBJECTIVE] We compared post-thoracotomy pain syndrome (PTPS) incidence in patients who underwent uniportal or multiportal video-assisted thoracoscopic surgery (VATS). [METHODS] We included 223 patients who underwent either uniportal or multiportal VATS between January 2017 and October 2018 (pulmonary lobectomies and p...
Minimally invasive surgery; Post-thoracotomy pain syndrome; Surgery; Uniportal VATS
null
2
Health Professions; Medicine
Health Professions; Medicine
2,023
35,142,091
Impact of early palliative care according to baseline symptom severity: Secondary analysis of a cluster-randomized controlled trial in patients with advanced cancer.
Cancer medicine
Cancer Med
11
8
10.1002/cam4.4565
eng
2,022
4
null
2,022
2
9
[BACKGROUND] Early palliative care (EPC) improves the quality of life but may not be feasible for all patients with advanced cancer. Symptom screening has been suggested to triage patients for EPC, but scant evidence exists for this practice. [METHODS] We conducted a subgroup analysis of a cluster-randomized controlled...
cancer; palliative care; quality of life; randomized controlled trial; secondary analysis; symptom assessment
1.188
95
Oncology; Radiology, Nuclear Medicine and Imaging; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,141,913
Study on the role of pyroptosis in bone resorption induced by occlusal trauma with or without periodontitis.
Journal of periodontal research
J Periodontal Res
57
3
10.1111/jre.12974
eng
2,022
6
null
2,022
2
9
[BACKGROUND AND OBJECTIVE] Occlusal trauma is considered to be a contributing factor to bone loss associated with inflammatory periodontal disease. We hypothesized that pyroptosis, a recently discovered inflammation-induced programmed cell death pathway, plays a role in occlusal trauma. [MATERIALS AND METHODS] The occl...
bone resorption; dental occlusion; glyburide; periodontitis; pyroptosis; traumatic
0.816
102
Periodontics
Dentistry
2,022
35,141,676
Why patients fail to achieve a Patient Acceptable Symptom State (PASS) after total shoulder arthroplasty?
JSES international
JSES Int
6
1
10.1016/j.jseint.2021.09.017
eng
2,022
1
null
2,021
11
17
[BACKGROUND] The purpose of this study was to compare patient-reported outcomes (PROs) and range of motion (ROM) measurements between patients achieving and failing to achieve a Patient Acceptable Symptom State (PASS) after anatomic total shoulder arthroplasty (TSA) to determine which PRO questions and ROM measurements...
ASES; American Shoulder and Elbow Surgeons; PASS; Patient Acceptable Symptom State; SANE; Single Assessment Numeric Evaluation; TSA; Total shoulder arthroplasty
0.68
28
Orthopedics and Sports Medicine; Surgery
Medicine
2,022
35,141,648
The effect of instrumentation staging on patient outcomes in pyogenic vertebral osteomyelitis: A systematic review.
North American Spine Society journal
N Am Spine Soc J
8
null
10.1016/j.xnsj.2021.100083
eng
2,021
12
null
2,021
10
8
[BACKGROUND] Pyogenic vertebral osteomyelitis is a bacterial infection of the vertebral body that is often treatable with antibiotics, but some cases require additional surgical debridement of the infected tissue. Instrumentation is often utilized for stabilization of the spine as part of the surgical treatment, but co...
Acute instrumentation; Debridement; Delayed instrumentation; Procedure staging; Spinal instrumentation; Vertebral osteomyelitis
null
null
null
null
null
35,141,635
Sagittal alignment at 3 years old determines future thoracolumbar kyphosis in achondroplasia: A prospective study with minimum 5-year follow-up from infancy.
North American Spine Society journal
N Am Spine Soc J
6
null
10.1016/j.xnsj.2021.100070
eng
2,021
6
null
2,021
5
13
[BACKGROUND] Little is known about the progression of Thoracolumbar kyphosis (TLK) in achondroplasia. The aim of the study was to evaluate natural progression of TLK and establish risk factors for progression. [METHODS] We reviewed 21 patients (11 males, 10 females) diagnosed clinically and radiographically with achond...
Achondroplasia; Natural progression; Sagittal alignment; Thoracolumbar kyphosis
null
null
null
null
null
35,141,510
Inducers of the NF-κB pathways impair hepatitis delta virus replication and strongly decrease progeny infectivity in vitro.
JHEP reports : innovation in hepatology
JHEP Rep
4
3
10.1016/j.jhepr.2021.100415
eng
2,022
3
null
2,021
12
14
[BACKGROUND AND AIMS] HDV superinfection of chronically HBV-infected patients is the most aggressive form of chronic viral hepatitis, with an accelerated progression towards fibrosis/cirrhosis and increased risk of liver failure, hepatocellular carcinoma, and death. While HDV infection is not susceptible to available d...
HDV-AG(s), HDV anti-genome(s); HDV-G(s), HDV genome(s); Hepatitis B virus; Hepatitis D virus; IFN, interferon; IL-, interleukin-; L-HDAg, large HDV antigen; NTCP, Na+-taurocholate cotransporting polypeptide; PHH, primary human hepatocyte; RNP, ribonucleoprotein; S-HDAg, small HDV antigen; TLR, Toll-like receptor; TNF, ...
2.907
55
Gastroenterology; Hepatology; Immunology and Allergy; Internal Medicine
Medicine
2,022
35,141,357
Lisdexamfetamine Therapy in Paroxysmal Non-kinesigenic Dyskinesia Associated with the KCNMA1-N999S Variant.
Movement disorders clinical practice
Mov Disord Clin Pract
9
2
10.1002/mdc3.13394
eng
2,022
2
null
2,021
12
21
[BACKGROUND] KCNMA1-linked channelopathy is a rare movement disorder first reported in 2005. Paroxysmal non-kinesigenic dyskinesia (PNKD) in KCNMA1-linked channelopathy is the most common symptom in patients harboring the KCNMA1-N999S mutation. PNKD episodes occur up to hundreds of times daily with significant morbidit...
BK channel; KCa1.1; PNKD type 3; movement disorder; stimulants
0.632
42
Neurology; Neurology
Medicine; Neuroscience
2,022
35,141,154
A Comparative Study on the Accuracy and Efficacy Between Dalton and CINtec[®] PLUS p16/Ki-67 Dual Stain in Triaging HPV-Positive Women.
Frontiers in oncology
Front Oncol
11
null
10.3389/fonc.2021.815213
eng
2,021
null
null
2,022
1
24
[BACKGROUND] CINtec[®] PLUS p16/Ki-67 dual-stained cytology (DS) is an alternative test to cytology in triaging human papillomavirus (HPV)-positive women. Dalton p16/Ki-67 Dual Stain kit employs the similar immunocytochemical detection and operating procedures with CINtec[®] PLUS, but its accuracy and efficacy in triag...
cervical cancer; cervical cancer screening; cervical intraepithelial neoplasia; human papillomavirus; p16/Ki-67 dual stain
1.291
156
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,021
35,140,786
Inflammation-Related Gene Signature: An Individualized Risk Prediction Model for Kidney Renal Clear Cell Carcinoma.
Journal of oncology
J Oncol
2022
null
10.1155/2022/2559258
eng
2,022
null
null
2,022
1
31
[BACKGROUND] There is much evidence that confirms the inextricable link between inflammation and malignancy. Inflammation-related regulators were involved in the progression of kidney renal clear cell carcinoma (KIRC). However, the predictive role of single gene biomarkers is inadequate, and more accurate prognostic mo...
null
null
null
null
null
null
35,140,569
Frequency of serum blood glucose monitoring after hyperkalaemia treatment using insulin and dextrose.
Journal of Taibah University Medical Sciences
J Taibah Univ Med Sci
17
1
10.1016/j.jtumed.2021.07.014
eng
2,022
2
null
2,021
9
4
[OBJECTIVES] In patients with hyperkalaemia, dextrose is administered alongside insulin treatment to prevent hypoglycaemia. However, the incidence of hypoglycaemia in the first 6 hours following this regimen remains high, and frequent blood glucose monitoring is essential. This study evaluates the frequency of blood gl...
Dextrose; Glucose; Hyperkalaemia; Hypoglycaemia; Insulin
0.418
37
Medicine
Medicine
2,022
35,139,863
CPNE1 is a potential prognostic biomarker, associated with immune infiltrates and promotes progression of hepatocellular carcinoma.
Cancer cell international
Cancer Cell Int
22
1
10.1186/s12935-022-02485-2
eng
2,022
2
9
2,022
2
9
[BACKGROUND] Copine1 (CPNE1), the first discovered CPNE1 family member, participates in the process of carcinogenesis and development of diverse tumors. Our study aimed to investigate the expression and prognostic value of CPNE1 gene in hepatocellular carcinoma (HCC), to explore its functional network in HCC and its ef...
AKT/P53; CPNE1; Hepatocellular carcinoma; Immune infiltration; Prognosis
1.145
90
Genetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,139,851
The superior accuracy of a novel method in total hip wear calculations following radiographic measurement.
BMC musculoskeletal disorders
BMC Musculoskelet Disord
23
1
10.1186/s12891-021-04964-5
eng
2,022
2
9
2,022
2
9
[BACKGROUND] Polyethylene wear is one of the major concerns of orthopedic surgeons. However, there is no standardized calculation method for the wear rate following radiographic measurement. The purpose of this study was to propose a novel method of wear calculation and to compare its accuracy with a representative con...
null
0.716
131
Orthopedics and Sports Medicine; Rheumatology
Medicine
2,022
35,139,541
Integrating landmark modeling framework and machine learning algorithms for dynamic prediction of tuberculosis treatment outcomes.
Journal of the American Medical Informatics Association : JAMIA
J Am Med Inform Assoc
29
5
10.1093/jamia/ocac003
eng
2,022
4
13
null
null
null
[OBJECTIVE] This study aims to establish an informative dynamic prediction model of treatment outcomes using follow-up records of tuberculosis (TB) patients, which can timely detect cases when the current treatment plan may not be effective. [MATERIALS AND METHODS] We used 122 267 follow-up records from 17 958 new case...
follow-up studies; mortality; supervised machine learning; treatment outcome; tuberculosis
2.44
184
Health Informatics
Medicine
2,022
35,139,527
Perspectives on Training and Working in the VHA: Implications for Primary Care Physician Recruitment and Retention.
Academic medicine : journal of the Association of American Medical Colleges
Acad Med
97
8
10.1097/ACM.0000000000004619
eng
2,022
8
1
2,022
7
21
[PURPOSE] The primary care physician shortage in the United States presents significant challenges for health systems seeking to maintain a sufficient primary care workforce. Perspectives on training or working in primary care in the Veterans Health Administration (VHA) may yield insights into strategic recruitment to ...
null
1.579
199
Education; Medicine
Medicine; Social Sciences
2,022
35,139,443
What is the impact of video as a teaching method on achieving psychomotor skills in nursing? A systematic review and meta-analysis.
Nurse education today
Nurse Educ Today
111
null
10.1016/j.nedt.2022.105280
eng
2,022
4
null
2,022
1
24
[OBJECTIVES] The aim of this systematic review (SR) is to establish if video is a beneficial teaching method when teaching psychomotor skills in nursing. [DESIGN] Systematic review. [DATA SOURCES] A database search of CINAHL, MEDLINE, EMBASE and Cochrane was performed with search terms 'video', 'nurse' 'RCT' and 'pract...
Meta-analysis; Nursing; Psychomotor skills; Systematic review; Teaching method; Video
0.946
109
Education; Nursing
Nursing; Social Sciences
2,022
35,139,416
Corticomotor plasticity as a predictor of response to high frequency transcranial magnetic stimulation treatment for major depressive disorder.
Journal of affective disorders
J Affect Disord
303
null
10.1016/j.jad.2022.02.005
eng
2,022
4
15
2,022
2
6
[BACKGROUND] Many patients with treatment-resistant depression (TRD) respond to repetitive transcranial magnetic stimulation (rTMS) treatment. This study aimed to investigate whether modulation of corticomotor excitability by rTMS predicts response to rTMS treatment for TRD in 10 Hz and intermittent theta-burst stimula...
Biomarker; Neuromodulation; Plasticity; Therapeutic intervention; Transcranial magnetic stimulation; Treatment-resistant depression
1.988
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
35,139,400
HCC surveillance improves early detection, curative treatment receipt, and survival in patients with cirrhosis: A meta-analysis.
Journal of hepatology
J Hepatol
77
1
10.1016/j.jhep.2022.01.023
eng
2,022
7
null
2,022
2
6
[BACKGROUND AND AIMS] There is controversy regarding the overall value of hepatocellular carcinoma (HCC) surveillance in patients with cirrhosis given the lack of data from randomized-controlled trials. To address this issue, we conducted a systematic review and meta-analysis of cohort studies evaluating the benefits a...
Screening; cirrhosis; early detection; liver cancer; ultrasound
7.398
319
Hepatology
Medicine
2,022
35,139,338
Photodynamic therapy during second surgery for recurrent gliomas improves survival.
Photodiagnosis and photodynamic therapy
Photodiagnosis Photodyn Ther
38
null
10.1016/j.pdpdt.2022.102754
eng
2,022
6
null
2,022
2
6
[BACKGROUND] Glioma accounts for most central nervous system tumors, and the degree of invasion and malignancy are higher in the recurrent glioma. Photodynamic therapy (PDT) is an effective strategy in glioma. This study aimed to explore the risk factors for re-recurrence after a second glioma surgery and the effects o...
Photodynamic therapy; Re-recurrence; Recurrent glioma; Risk factor
0.633
73
Biophysics; Dermatology; Pharmacology; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,139,044
ED 90 of Intrathecal Chloroprocaine With Fentanyl for Prophylactic Cervical Cerclage: A Sequential Allocation Biased-Coin Design.
Anesthesia and analgesia
Anesth Analg
134
4
10.1213/ANE.0000000000005927
eng
2,022
4
1
null
null
null
[BACKGROUND] Chloroprocaine is a short-acting local anesthetic that has been used for spinal anesthesia in outpatient surgery. There is limited experience with spinal chloroprocaine for prophylactic cervical cerclage placement. We sought to determine the effective dose of intrathecal chloroprocaine for 90% of patients ...
null
1.365
237
Anesthesiology and Pain Medicine
Medicine
2,022
35,138,573
Infection Rate in Seabasses Fed with Viscera Parasitised by Anisakid Larvae.
Acta parasitologica
Acta Parasitol
67
2
10.1007/s11686-022-00525-5
eng
2,022
6
null
2,022
2
9
[PURPOSE] It has been suggested that the removal of infected viscera on board is responsible for the high prevalence of anisakid larvae present in wild fish species. The aim of this work is to assess the re-infection capacity of anisakid larvae in European seabasses, a natural host species for the parasite by feeding w...
Anisakis; Discarding; Life cycle; Re-infection; Seabass; Viscera
0.478
43
Parasitology
Immunology and Microbiology
2,022
35,137,399
Intracranial hypotension as a contributor to isolated cortical vein thrombosis.
Headache
Headache
62
2
10.1111/head.14254
eng
2,022
2
null
2,022
2
8
[BACKGROUND] Isolated cortical vein thrombosis (ICVT), a rare type of cerebral venous thrombosis (CVT), is diagnostically challenging in some cases, and intracranial hypotension (IH) is known to cause CVT. [METHODS] In this study, we reviewed the clinical and imaging characteristics of ICVT in patients with IH caused b...
intracranial hypotension; isolated cortical vein thrombosis; post-dural puncture headache; spontaneous intracranial hypotension
1.283
146
Neurology; Neurology
Medicine; Neuroscience
2,022
35,136,778
Morbidity profile of under-5 slum dwellers of Amritsar city: A descriptive cross-sectional study.
Journal of family medicine and primary care
J Family Med Prim Care
10
11
10.4103/jfmpc.jfmpc_110_21
eng
2,021
11
null
2,021
11
29
[CONTEXT] Children living in slums are deprived from basic necessities. Unhygienic environment and deficient nutrition hinder their growth and make them more prone to infectious diseases. [AIMS] To study morbidity profile of under-5 children and determine social epidemiological factors associated with it. [SETTINGS AND...
Anaemia; malnutrition; morbidity; under-5 children; urban slums
null
null
null
null
null
35,136,603
Allogeneic CD20-targeted γδ T cells exhibit innate and adaptive antitumor activities in preclinical B-cell lymphoma models.
Clinical & translational immunology
Clin Transl Immunology
11
2
10.1002/cti2.1373
eng
2,022
null
null
2,022
2
2
[OBJECTIVES] Autologous chimeric antigen receptor (CAR) αβ T-cell therapies have demonstrated remarkable antitumor efficacy in patients with haematological malignancies; however, not all eligible cancer patients receive clinical benefit. Emerging strategies to improve patient access and clinical responses include using...
CD20; adoptive cell therapy; chimeric antigen receptor
null
null
null
null
null
35,136,416
Krüppel-Like Factor 6 Downregulation Is Connected with a Poor Prognosis and Tumor Growth in Non-Small-Cell Lung Cancer.
Computational and mathematical methods in medicine
Comput Math Methods Med
2022
null
10.1155/2022/3193553
eng
2,022
null
null
2,022
1
30
[PURPOSE] Research in this article was performed to explore the biological role and clinical significance of Krüppel-like transcription factor 6 (KLF6) in non-small-cell lung cancer (NSCLC). [METHODS] KLF6 expression in NSCLC cell lines was analyzed using reverse transcription PCR and Western blot. The expressed KLF6 p...
null
null
null
null
null
null
35,135,777
Exploring digital health interventions for pregnant women at high risk for pre-eclampsia and eclampsia in low-income and-middle-income countries: a scoping review.
BMJ open
BMJ Open
12
2
10.1136/bmjopen-2021-056130
eng
2,022
2
8
2,022
2
8
[OBJECTIVE] To explore digital health interventions that have been used to support pregnant women at high risk for pre-eclampsia/eclampsia (HRPE/E) in low-income and middle-income countries (LMICs). [DESIGN] Scoping review. [DATA SOURCE] EMBASE, MEDLINE, Cochrane Central Register of Controlled Trials, Cochrane Database...
health informatics; prenatal diagnosis; public health; telemedicine
1.059
176
Medicine
Medicine
2,022
35,135,698
PCSK9 promotes arterial medial calcification.
Atherosclerosis
Atherosclerosis
346
null
10.1016/j.atherosclerosis.2022.01.015
eng
2,022
4
null
2,022
1
22
[BACKGROUND AND AIMS] A complex interplay among chronic kidney disease (CKD), lipid metabolism and aortic calcification has been recognized. Here we investigated the influence of kidney function on PCSK9 levels and its potential direct action on smooth muscle cells (SMCs) calcification. [METHODS AND RESULTS] In a cohor...
Calcification; Chronic kidney disease; PCSK9; Smooth muscle cells; Vescicles
1.375
201
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,135,526
Preoperative management and postoperative complications associated with transoral decompression for the upper cervical spine.
BMC musculoskeletal disorders
BMC Musculoskelet Disord
23
1
10.1186/s12891-022-05081-7
eng
2,022
2
8
2,022
2
8
[PURPOSE] This review aimed to describe the preoperative management and postoperative complications associated with transoral decompression of the upper cervical spine, and to clarify the risk factors, related issues and complication management. [METHODS] Studies on transoral decompression for the upper cervical spine ...
Complications; Preoperative management; Transoral decompression; Upper cervical spine
0.716
131
Orthopedics and Sports Medicine; Rheumatology
Medicine
2,022
35,135,524
The effects of involvement in training and volunteering with families of people with dementia on the knowledge and attitudes of volunteers towards dementia.
BMC public health
BMC Public Health
22
1
10.1186/s12889-022-12687-y
eng
2,022
2
8
2,022
2
8
[BACKGROUND] Volunteers have been a valuable resource in supporting people with dementia and their caregivers in the community. However, factors such as misconceptions, negative attitudes towards dementia, and a lack of motivation might impact the quality of volunteer care. The present paper aims to examine the effect ...
Dementia attitudes; Dementia knowledge; Motivation to volunteer; Public health; Service; Training; Volunteer
1.307
211
Public Health, Environmental and Occupational Health
Medicine
2,022
35,135,340
Intermittent Versus Continuous Infusion Dosing of Intravenous Proton Pump Inhibitors for Upper Gastrointestinal Bleeding.
The Annals of pharmacotherapy
Ann Pharmacother
56
10
10.1177/10600280211073936
eng
2,022
10
null
2,022
2
8
[BACKGROUND] Proton pump inhibitor (PPI) continuous infusions or intermittent boluses are used for the treatment of upper gastrointestinal bleeding (UGIB). Intermittent boluses are easier to give and are of lower cost without affecting clinical outcomes. [OBJECTIVE] To compare the rate of rebleeding between intermitten...
continuous infusion; proton pump inhibitors; upper gastrointestinal bleeding
0.891
125
Medicine; Pharmacology
Medicine
2,022
35,135,323
Improvements in Endovascular Treatment for Acute Ischemic Stroke: A Longitudinal Study in the MR CLEAN Registry.
Stroke
Stroke
53
6
10.1161/STROKEAHA.121.034919
eng
2,022
6
null
2,022
2
9
[BACKGROUND] We evaluated data from all patients in the Netherlands who underwent endovascular treatment for acute ischemic stroke in the past 3.5 years, to identify nationwide trends in time to treatment and procedural success, and assess their effect on clinical outcomes. [METHODS] We included patients with proximal ...
groin odds; puncture; ratio; registry; reperfusion
2.746
370
Advanced and Specialized Nursing; Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neuroscience
Medicine; Neuroscience; Nursing
2,022
35,134,953
Educational attainment as a modifier for the effect of polygenic scores for cardiovascular risk factors: cross-sectional and prospective analysis of UK Biobank.
International journal of epidemiology
Int J Epidemiol
51
3
10.1093/ije/dyac002
eng
2,022
6
13
null
null
null
[BACKGROUND] Understanding the interplay between educational attainment and genetic predictors of cardiovascular risk may improve our understanding of the aetiology of educational inequalities in cardiovascular disease. [METHODS] In up to 320 120 UK Biobank participants of White British ancestry (mean age = 57 years, f...
Polygenic scores; cardiovascular disease; education; gene*environment interactions; inequalities
2.815
256
Epidemiology; Medicine
Medicine
2,022
35,134,908
Role of anatomical regurgitant orifice area and right ventricular contractile reserve in severe tricuspid regurgitation.
European heart journal. Cardiovascular Imaging
Eur Heart J Cardiovasc Imaging
23
7
10.1093/ehjci/jeac004
eng
2,022
6
21
null
null
null
[AIMS] We sought to propose a novel risk stratification system for severe tricuspid regurgitation (TR) using 3D-anatomical regurgitant orifice area (3D-AROA) and the slope of tricuspid annular plane systolic excursion vs. systolic pulmonary artery pressure (TAPSE/SPAP) and to validate its prognostic significance. [METH...
3D echocardiography; prognosis; tricuspid regurgitation
null
null
null
null
null
35,134,874
A retrospective study on adherence to secondary prevention medications after coronary bypass surgery.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Eur J Cardiothorac Surg
62
4
10.1093/ejcts/ezac054
eng
2,022
9
2
null
null
null
[OBJECTIVES] We assessed adherence to statins, beta-blockers and renin-angiotensin system (RAS) inhibitors after coronary artery bypass graft surgery and factors associated with non-adherence. [METHODS] This nationwide retrospective cohort study included all individuals undergoing coronary artery bypass surgery from 22...
Coronary disease; Myocardial protection
1.183
158
Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,022
35,133,926
Beliefs affecting concussion reporting among military cadets: advanced observations through machine learning.
Brain injury
Brain Inj
36
2
10.1080/02699052.2022.2034945
eng
2,022
1
28
2,022
2
8
[BACKGROUND] Untreated concussions are an important health concern. The number of concussions sustained each year is difficult to pinpoint due to diverse reporting routes and many people not reporting. A growing body of literature investigates the motivations for concussion under-reporting, proposing ties with knowledg...
Concussion reporting; automated classification; concussion beliefs; factor analysis; reporting intentions
0.567
122
Developmental and Educational Psychology; Neurology; Neuroscience
Medicine; Neuroscience; Psychology
2,022
35,133,906
Toward evidence-informed child rearing: Measurement of time-out implementation in a community sample.
Clinical child psychology and psychiatry
Clin Child Psychol Psychiatry
28
2
10.1177/13591045221076644
eng
2,023
4
null
2,022
2
8
[BACKGROUND] Time-out (TO) is a widely used parental discipline strategy with strong research support in programmes that promote positive child development. Concerns have been raised, however, regarding adverse impact on child mental health (CMH) in part driven by evidence of widespread variability in appropriate imple...
Parenting; child mental health; discipline; time-out
0.808
67
Pediatrics, Perinatology and Child Health; Clinical Psychology; Medicine; Psychiatry and Mental Health
Medicine; Psychology
2,023
35,133,607
Creatine kinase-(MB) and hepcidin as candidate biomarkers for early diagnosis of pulmonary tuberculosis: a proof-of-concept study in Lambaréné, Gabon.
Infection
Infection
50
4
10.1007/s15010-022-01760-8
eng
2,022
8
null
2,022
2
8
[BACKGROUND] The present study aimed to evaluate the diagnostic utility of creatine kinase-MB (CK-MB), hepcidin (HEPC), phospholipase A2 group IIA (PLa2G2A), and myosin-binding protein C (MYBPC1) for tuberculosis (TB). These four biomarkers are differentially regulated between quiescent Mycobacterium tuberculosis (Mtb)...
Biomarkers; Creatine kinase-MB; Diagnosis; Hepcidin; Tuberculosis
1.488
94
Infectious Diseases; Medicine; Microbiology
Medicine
2,022
35,133,578
Anti-TNF Induced Sarcoidosis-Like Disease in Rheumatoid Arthritis Patients: Review Cases from the RA UCLouvain Brussels Cohort.
Rheumatology and therapy
Rheumatol Ther
9
2
10.1007/s40744-022-00424-1
eng
2,022
4
null
2,022
2
8
[INTRODUCTION] Drug-induced sarcoidosis-like disease is a rare side effect of anti-tumor necrosis factor (anti-TNF) agents in rheumatoid arthritis (RA) patients. The most commonly involved organs in such condition are the lungs, skin, and lymph nodes. The aim of this study is to report the number of cases and the clini...
Anti-TNF; Drug-induced sarcoidosis; Rheumatoid arthritis; Sarcoidosis; Tumor necrosis factor inhibitor
1.242
40
Rheumatology; Immunology and Allergy
Medicine
2,022
35,133,531
Chest CT severity score: assessment of COVID‑19 severity and short-term prognosis in hospitalized Iranian patients.
Wiener medizinische Wochenschrift (1946)
Wien Med Wochenschr
172
3-4
10.1007/s10354-022-00914-5
eng
2,022
3
null
2,022
2
8
[BACKGROUND] The aim of this study was to evaluate the value of chest computed tomography (CT) severity score in the assessment of coronavirus disease 2019 (COVID‑19) severity and short-term prognosis. [METHODS] In this cross-sectional study, we evaluated all patients who were referred to our university hospital, from ...
Computed tomography scan; Computed tomography severity score; Coronavirus disease 2019; Mortality; Severity
null
null
null
null
null
35,133,336
Sarcoplasmic reticulum Ca[2+] ATPases genes differential expression in breast cancer cells.
Gaceta medica de Mexico
Gac Med Mex
157
4
10.24875/GMM.M21000573
eng
2,021
null
null
null
null
null
[INTRODUCTION] Sarcoplasmic reticulum Ca[2+] ATPases (SERCA) enzymes are essential for intracellular Ca[2+] homeostasis. SERCA genes (ATP2A1-3) encode for different functional isoforms of the protein, whose expression or function is altered in several types of cancer, such as gastric and oral, as well as colon, breast,...
Calcio; Calcium; Cancer; Gene expression; SERCA
null
null
null
null
null
35,132,664
Hemodynamic assessment and risk classification for successful weaning of Impella in patients with cardiogenic shock.
Artificial organs
Artif Organs
46
7
10.1111/aor.14197
eng
2,022
7
null
2,022
2
19
[BACKGROUND] Clinical predictors for successful weaning of patients from Impella heart pump have not been clarified. We aimed to elucidate the relationship between pulmonary artery catheter (PAC) parameters at the time of Impella weaning and subsequent outcomes. [METHODS] We enrolled consecutive patients who had receiv...
hemodynamics; mechanical circulatory support; outcome; pulmonary artery catheterization; weaning
0.522
88
Medicine; Bioengineering; Biomaterials; Biomedical Engineering
Chemical Engineering; Engineering; Materials Science; Medicine
2,022
35,132,657
Review article: randomised controlled trials in inflammatory bowel disease-common challenges and potential solutions.
Alimentary pharmacology therapeutics
Aliment Pharmacol Ther
55
6
10.1111/apt.16781
eng
2,022
3
null
2,022
2
7
[BACKGROUND] Recruitment rates for Crohn's disease and ulcerative colitis clinical trials continue to decrease annually. The inability to reach recruitment targets and complete trials has serious implications for stakeholders in the inflammatory bowel disease (IBD) community. Action is required to ensure patients with ...
null
null
null
null
null
null
35,132,330
Identifying Obstructive Sleep Apnea Syndrome-Associated Genes and Pathways through Weighted Gene Coexpression Network Analysis.
Computational and mathematical methods in medicine
Comput Math Methods Med
2022
null
10.1155/2022/3993509
eng
2,022
null
null
2,022
1
29
[BACKGROUND] Obstructive sleep apnea syndrome (OSAS) is the most common type of sleep apnea disorder. The disease seriously affects the patient's respiratory system. At present, the prognosis of the disease is poor and there is a lack of effective treatments. Therefore, it is urgent to explore its pathogenesis and trea...
null
null
null
null
null
null
35,132,013
Reliability and Validity of an MRI-Based Knee Sagittal Alignment Measure in a Pediatric Cohort.
Journal of pediatric orthopedics
J Pediatr Orthop
42
4
10.1097/BPO.0000000000002078
eng
2,022
4
1
null
null
null
[BACKGROUND] Magnetic resonance imaging (MRI) sagittal alignment is a measure that has been described and validated in the adult population as a means of distinguishing normal knees from those with anterior cruciate ligament (ACL) injury, but this measure has not been formally assessed among pediatric patients. The pur...
null
null
null
null
null
null
35,132,011
The Clinical Significance of Infolded Limbus on Postreduction Arthrogram in Developmental Dysplasia of the Hip.
Journal of pediatric orthopedics
J Pediatr Orthop
42
4
10.1097/BPO.0000000000002070
eng
2,022
4
1
null
null
null
[BACKGROUND] The purpose of this study was to investigate whether presence of an infolded limbus on hip arthrogram at index closed reduction was associated with increased residual dysplasia or secondary surgery. [METHODS] We retrospectively reviewed all patients who underwent closed reduction for dysplasia of the hip w...
null
null
null
null
null
null