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35,579,515
Arrhythmogenic Right Ventricular Cardiomyopathy Prevalence and Arrhythmic Outcomes in At-Risk Family Members: A Systematic Review and Meta-Analysis.
Circulation. Genomic and precision medicine
Circ Genom Precis Med
15
3
10.1161/CIRCGEN.121.003530
eng
2,022
6
null
2,022
5
17
[BACKGROUND] Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a complex cardiomyopathy with autosomal dominant inheritance and age-related incomplete penetrance, characterized by a high risk of sudden cardiac death. Recent professional consensus guidelines recommend clinical cardiac lifelong serial screening f...
cardiomyopathy; diagnosis; family; genotype; prevalence
null
null
null
null
null
35,578,883
Erythroxylum cuneatum Prevented Cellular Adaptation in Morphineinduced Neuroblastoma Cells.
Central nervous system agents in medicinal chemistry
Cent Nerv Syst Agents Med Chem
22
2
10.2174/1871524922666220516151121
eng
2,022
null
null
null
null
null
[BACKGROUND] Chronic morphine stimulates prolonged stimulation of opioid receptors, especially μ-opioid subtype (MOR), which in turn signals cellular adaptation. However, the sudden termination of the use of morphine after chronic intake causes the withdrawal syndrome. [OBJECTIVES] Hence, this study was designed to fin...
Erythroxylum cuneatum; anti-addiction; cellular adaptation; chronic morphine; human neuroblastoma cell line (SK-N-SH); methadone
null
null
null
null
null
35,578,841
Patient and Healthcare Professional Satisfaction with the OneTouch Verio Reflect[®] Blood Glucose Monitoring System in the UAE.
Current diabetes reviews
Curr Diabetes Rev
19
3
10.2174/1573399818666220516101041
eng
2,023
null
null
null
null
null
[AIMS] The goal of this study was to collect the opinions of patients and HCPs who used OneTouch Verio Reflect[®] in the United Arab Emirates (UAE). [BACKGROUND] Blood glucose monitoring devices are essential tools that aid healthcare professionals (HCPs) in improving outcomes in people with diabetes. [OBJECTIVES] To a...
ColorSure; OneTouch Verio reflect; blood glucose monitoring; diabetes; mobile application; preference
0.765
73
Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
35,578,244
A novel nanobody as therapeutics target for EGFR-positive colorectal cancer therapy: exploring the effects of the nanobody on SW480 cells using proteomics approach.
Proteome science
Proteome Sci
20
1
10.1186/s12953-022-00190-6
eng
2,022
5
16
2,022
5
16
[BACKGROUND] The epidermal growth factor receptor (EGFR) overexpression is found in metastatic colorectal cancer (mCRC). Targeted molecular therapies such as monoclonal antibodies (mAbs) and tyrosine kinase inhibitors (TKI) are becoming more precise, targeting specifically for cancer therapeutics. However, there are ad...
Antibodies; Gefitinib; Protein interactions; SW480; Tyrosine kinase inhibitors
0.394
56
Biochemistry; Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,022
35,578,168
Which features of ambulatory healthcare are preferred by people aged 80 and over? Findings from a systematic review of qualitative studies and appraisal of confidence using GRADE-CERQual.
BMC geriatrics
BMC Geriatr
22
1
10.1186/s12877-022-03006-6
eng
2,022
5
16
2,022
5
16
[BACKGROUND] Despite healthcare providers' goal of patient-centeredness, current models for the ambulatory (i.e., outpatient) care of older people have not as yet systematically incorporated their views. Moreover, there is no systematic overview of the preferable features of ambulatory care from the perspective of peop...
Aged, 80 and over; Ambulatory care; Patient preferences; Patient-centered care; Qualitative research; Systematic review
1.127
112
Geriatrics and Gerontology
Medicine
2,022
35,577,995
Revisiting Kümmell's disease: MRI findings beyond the intraosseous cavity for improved diagnosis.
Neuroradiology
Neuroradiology
64
8
10.1007/s00234-022-02976-z
eng
2,022
8
null
2,022
5
17
[PURPOSE] The diagnostic tool for Kümmell's disease (KD), including the intravertebral vacuum cavity on imaging, is still limited. The purpose of this study was to find other magnetic resonance imaging (MRI) findings that could help the diagnosis of KD. [METHODS] A total of 289 patients (103 males and 186 females with ...
Intraosseous cavity; MRI; Osteonecrosis; Prevertebral soft tissue
0.823
109
Radiology, Nuclear Medicine and Imaging; Cardiology and Cardiovascular Medicine; Neurology
Medicine
2,022
35,577,395
Long-term modification of gut microbiota by broad-spectrum antibiotics improves stroke outcome in rats.
Stroke and vascular neurology
Stroke Vasc Neurol
7
5
10.1136/svn-2021-001231
eng
2,022
10
null
2,022
5
16
[BACKGROUND] The brain-gut axis is a major regulator of the central nervous system. We investigated the effects of treatment with broad-spectrum antibiotics on gut and brain inflammation, infarct size and long-term behavioral outcome after cerebral ischemia in rats. [METHODS] Rats were treated with broad-spectrum antib...
Cerebral Infarction; Stroke; Stroke Rehabilitation
1.735
46
Cardiology and Cardiovascular Medicine; Neurology
Medicine
2,022
35,576,731
Non-optimum ambient temperature may decrease pulmonary function: A longitudinal study with intensively repeated measurements among asthmatic adult patients in 25 Chinese cities.
Environment international
Environ Int
164
null
10.1016/j.envint.2022.107283
eng
2,022
6
null
2,022
5
10
[BACKGROUND] Non-optimum ambient temperature has not been widely perceived as an important environmental risk factor for asthma, and the association between ambient temperature and pulmonary function is rarely explored. Our study aimed to investigate the associations between non-optimum ambient temperature and pulmonar...
Ambient temperature; Asthma; Longitudinal study; Non-optimum ambient temperature; Pulmonary function
3.075
274
Environmental Science
Environmental Science
2,022
35,576,562
Readability of English, German, and Russian Disease-Related Wikipedia Pages: Automated Computational Analysis.
Journal of medical Internet research
J Med Internet Res
24
5
10.2196/36835
eng
2,022
5
16
2,022
5
16
[BACKGROUND] Wikipedia is a popular encyclopedia for health- and disease-related information in which patients seek advice and guidance on the web. Yet, Wikipedia articles can be unsuitable as patient education materials, as investigated in previous studies that analyzed specific diseases or medical topics with a compa...
Wikipedia; health education; health literacy; readability
1.992
214
Health Informatics
Medicine
2,022
35,576,496
Hsa_circ_0001982 promotes the proliferation, invasion, and multidrug resistance of osteosarcoma cells.
Journal of clinical laboratory analysis
J Clin Lab Anal
36
7
10.1002/jcla.24493
eng
2,022
7
null
2,022
5
16
[BACKGROUND] Osteosarcoma (OS) is the most common bone cancer mostly seen in people aged 10-25 years. This research aims to clarify the function of hsa_circ_0001982 in osteosarcoma (OS) and its effect on drug resistance, preliminarily exploring its mechanism. [METHODS] The expression of hsa_circ_0001982 and miR-143 in ...
hsa_circ_0001982; miR-143; molecular sponge; multidrug resistance; osteosarcoma
0.594
67
Medical Laboratory Technology; Biochemistry; Clinical Biochemistry; Public Health, Environmental and Occupational Health; Hematology; Immunology and Allergy; Microbiology
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine
2,022
35,576,095
Impact of Intragastric Balloon Placement on the Stomach Wall: A Prospective Cohort Study.
Obesity surgery
Obes Surg
32
7
10.1007/s11695-022-06101-0
eng
2,022
7
null
2,022
5
16
[PURPOSE] Endoscopic intragastric balloon (IGB) placement is a minimally invasive treatment for morbid obesity that is sometimes used as a preparatory step before surgical intervention. This study was performed to analyze the changes in the stomach wall induced by IGB placement, with particular emphasis on pathomorphol...
Intragastric balloon; Pathomorphology; Sleeve gastrectomy
1.127
164
Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics; Surgery
Medicine; Nursing
2,022
35,576,074
Checkpoint-inhibitor induced Polyserositis with Edema.
Cancer immunology, immunotherapy : CII
Cancer Immunol Immunother
71
12
10.1007/s00262-022-03211-7
eng
2,022
12
null
2,022
5
16
[BACKGROUND] As immune checkpoint inhibitors (ICI) are increasingly being used due to effectiveness in various tumor entities, rare side effects occur more frequently. Pericardial effusion has been reported in patients with advanced non-small cell lung cancer (NSCLC) after or under treatment with immune checkpoint inhi...
Anti-PD1-antibody; Autoimmunity; Pericardial effusion; Pleural effusion; Serositis; Side effects
1.663
142
Cancer Research; Immunology; Immunology and Allergy; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,022
35,575,946
Patient-specific dosimetry adapted to variable number of SPECT/CT time-points per cycle for 177 Lu-DOTATATE therapy.
EJNMMI physics
EJNMMI Phys
9
1
10.1186/s40658-022-00462-2
eng
2,022
5
16
2,022
5
16
[BACKGROUND] The number of SPECT/CT time-points is important for accurate patient dose estimation in peptide receptor radionuclide therapy. However, it may be limited by the patient's health and logistical reasons. Here, an image-based dosimetric workflow adapted to the number of SPECT/CT acquisitions available through...
Dosimetry; Internal radiotherapy; Lu-DOTATATE; Monte Carlo simulation; Patient-specific; SPECT/CT; Single acquisition
1.174
41
Biomedical Engineering; Instrumentation; Radiation; Radiology, Nuclear Medicine and Imaging
Engineering; Medicine; Physics and Astronomy
2,022
35,575,766
Influence of Minimum Alveolar Concentration and Inhalation Duration of Sevoflurane on Facial Nerve Electromyography in Hemifacial Spasm: A Randomized Controlled Trial.
Journal of neurosurgical anesthesiology
J Neurosurg Anesthesiol
35
4
10.1097/ANA.0000000000000848
eng
2,023
10
1
2,022
5
17
[BACKGROUND] The lateral spread response (LSR) is an electromyography feature of hemifacial spasm; intraoperative reduction in the LSR is associated with positive surgical outcomes. This study examined the effects of different minimum alveolar concentrations (MACs) and durations of sevoflurane inhalation on the LSR. [M...
null
null
null
null
null
null
35,575,666
The role of donor-recipient gender matching in lung transplantation: a systematic review.
Minerva surgery
Minerva Surg
77
4
10.23736/S2724-5691.22.09576-4
eng
2,022
8
null
2,022
5
16
[INTRODUCTION] Donor to recipient (D-R) matching in lung transplantation (LTx) is firstly directed by blood group (identity or compatibility), immunological status and morphological criteria. Sex matching is ignored and impact on outcome less investigated. [EVIDENCE ACQUISITION] Systematic review of English literature ...
null
0.195
28
Surgery
Medicine
2,022
35,575,188
Non-traumatic acute myelopathies: Clinical and imaging features in a real world emergency setting.
The neuroradiology journal
Neuroradiol J
35
6
10.1177/19714009221096823
eng
2,022
12
null
2,022
5
16
[OBJECTIVE] The aetiologic diagnosis of non-traumatic acute myelopathies (AMs), and their differentiation from other mimicking conditions (i.e. 'mimics'), are clinically challenging, especially in the emergency setting. Here, we sought to identify: (i) red flags suggesting diagnoses alternative to AMs and (ii) clinical...
Spinal cord; acute myelopathy; emergency room; magnetic resonance imaging
0.415
33
Medicine; Neurology; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,574,622
VNTR Polymorphism in Intron 4 of the eNOS Gene and the Risk of Gastrointestinal Bleeding: A Case-control Study.
Journal of gastrointestinal and liver diseases : JGLD
J Gastrointestin Liver Dis
31
2
10.15403/jgld-4226
eng
2,022
6
12
2,022
6
12
[BACKGROUND AND AIMS] Considering the lack of knowledge regarding the influence of the variable number of repeats of 27 pb in intron 4 (4b/4a VNTR - rs61722009) of the endothelial nitric oxide synthase (eNOS) on the drug response, we assessed the influence of this polymorphism for the risk of upper gastrointestinal ble...
null
0.588
62
Medicine; Gastroenterology
Medicine
2,022
35,574,557
Perioperative Management of Patient with Esophageal Carcinoma and Crigler-Najjar Syndrome Type 2: A Case Report.
Frontiers in surgery
Front Surg
9
null
10.3389/fsurg.2022.889753
eng
2,022
null
null
2,022
4
27
[BACKGROUND] Crigler-Najjar syndrome type 2 (CNS-II) is a rare genetic disease that is associated with a lack of uridine diphosphate-glucuronosyltransferase. Esophageal carcinoma is the sixth most common cause of cancer-related death worldwide, for which surgery is the most effective treatment. Reports on patients with...
Crigler-Najjar syndrome type 2; Esophageal carcinoma; case report; esophageal squamous cell carcinoma; perioperative management; surgery
0.459
48
Surgery
Medicine
2,022
35,573,064
Outcomes and predictors of early emergency department discharge among children with acute gastroenteritis and moderate dehydration.
International journal of pediatrics adolescent medicine
Int J Pediatr Adolesc Med
9
1
10.1016/j.ijpam.2021.03.003
eng
2,022
3
null
2,021
3
11
[BACKGROUND] Gastroenteritis is one of the most common diseases that affects children and remains a leading cause of morbidity and mortality around the world. There is conflicting evidence regarding the effect of rapid intravenous fluid regimen on the clinical outcome of patients with acute gastroenteritis. This study ...
Acute gastroenteritis; Bicarbonate; ED revisits; Emergency department; Intravenous fluid
null
null
null
null
null
35,572,990
Treatment Strategies in Emergency Endoscopy for Acute Esophageal Variceal Bleeding (CHESS1905): A Nationwide Cohort Study.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.872881
eng
2,022
null
null
2,022
4
27
[BACKGROUND AND AIMS] Emergency endoscopy is recommended for patients with acute esophageal variceal bleeding (EVB) and their prognosis has improved markedly over past decades due to the increased specialization of endoscopic practice. The study aimed to compare outcomes following emergency endoscopic injection sclerot...
emergency endoscopy; endoscopic injection sclerotherapy; endoscopic variceal ligation; liver cirrhosis; portal hypertension
0.926
102
Medicine
Medicine
2,022
35,572,955
Clinical Outcome of Viral Respiratory Tract Infections in Hospitalized Adults in Norway: High Degree of Inflammation and Need of Emergency Care for Cases With Respiratory Syncytial Virus.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.866494
eng
2,022
null
null
2,022
4
29
[BACKGROUND] The clinical features and outcomes of viral respiratory tract infections (RTIs) in adults have not been thoroughly studied, especially the respiratory syncytial virus (RSV) disease burden. It has become apparent that outbreaks of RSV in the elderly are associated with increased hospitalization rates. Howev...
Adults; antibiotic; hospitalization; human metapneumovirus (hMPV); influenza; viral respiratory tract infection
0.926
102
Medicine
Medicine
2,022
35,572,907
Trichosanthin inhibits cell growth and metastasis by promoting pyroptosis in non-small cell lung cancer.
Journal of thoracic disease
J Thorac Dis
14
4
10.21037/jtd-22-282
eng
2,022
4
null
null
null
null
[BACKGROUND] A number of studies have demonstrated that trichosanthin (TCS) can induce apoptosis in numerous types of tumor cell lines. However, whether TCS can induce pyroptosis has not yet been reported. This study aimed to investigate the role of TCS and its inhibitory effect on tumor growth by modulating pyroptosis...
Trichosanthin (TCS); invasion; migration; non-small cell lung cancer (NSCLC); pyroptosis
0.646
95
Pulmonary and Respiratory Medicine
Medicine
2,022
35,572,658
Grocott Methenamine Silver Staining Is the Optimal Approach to Histological Diagnosis of Pulmonary Cryptococcosis.
Frontiers in microbiology
Front Microbiol
13
null
10.3389/fmicb.2022.885511
eng
2,022
null
null
2,022
4
29
[BACKGROUND] Histological staining methods for Cryptococcus identification vary in accuracy. This study aimed to investigate the clinical value of Grocott methenamine silver (GMS), periodic acid-Schiff (PAS), and Alcian blue (AB) staining in the diagnosis of pulmonary cryptococcosis (PC). [METHODS] From April 2004 to J...
Alcian blue; Grocott methenamine silver; histology; periodic acid-Schiff; pulmonary cryptococcosis
1.19
259
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,022
35,572,395
High value-added application of a renewable bioresource as acaricide: Investigation the mechanism of action of scoparone against Tetranychus cinnabarinus.
Journal of advanced research
J Adv Res
38
null
10.1016/j.jare.2021.08.013
eng
2,022
5
null
2,021
8
23
[INTRODUCTION] Investigation into the action mechanisms of plant secondary metabolites against pests is a vital strategy for the development of novel promising biopesticides. Scoparone (isolated from Artemisia capillaris), a renewable plant-derived bioresource, displays potent acaricidal activities against mites, but i...
L-type Ca2+ channel; Mechanism of action; Scoparone; Spider mites
1.603
108
Multidisciplinary
Multidisciplinary
2,022
35,571,986
Impact of childhood cerebellar tumor surgery on cognition revealed by precuneus hyperconnectivity.
Neuro-oncology advances
Neurooncol Adv
4
1
10.1093/noajnl/vdac050
eng
2,022
null
null
2,022
4
13
[BACKGROUND] Childhood cerebellar pilocytic astrocytomas harbor excellent overall survival rates after surgical resection, but the patients may exhibit specific cognitive and behavioral problems. Functional MRI has catalyzed insights into brain functional systems and has already been linked with the neuropsychological ...
cerebellar pilocytic astrocytoma; cognitive outcome; precuneus; resting state functional MRI
1.052
33
Neurology; Surgery; Oncology
Medicine
2,022
35,571,967
Ligament Augmentation Reconstruction System (LARS) for Ankle Lateral Ligament Reconstruction in Higher-Risk Patients: A 5-Year Prospective Cohort Study.
Orthopaedic journal of sports medicine
Orthop J Sports Med
10
5
10.1177/23259671221093968
eng
2,022
5
null
2,022
5
9
[BACKGROUND] The modified Broström-Gould (MBG) procedure is the gold standard for patients with chronic ankle instability (CAI), but it is relatively contraindicated for patients with higher body weight or generalized ligamentous laxity (GLL). The use of the ligament augmentation reconstruction system (LARS) is an alte...
BMI; GLL; LARS ligament; ankle instability
1.113
68
Orthopedics and Sports Medicine
Medicine
2,022
35,571,622
Nutritional counseling was insufficient to maintain dietary intake and nutritional status in head and neck cancer patients undergoing radiotherapy: A historical control study for future intervention in China.
Asia-Pacific journal of oncology nursing
Asia Pac J Oncol Nurs
9
4
10.1016/j.apjon.2022.01.013
eng
2,022
4
null
2,022
2
12
[OBJECTIVE] To determine whether nutritional counseling (NC) affects the dietary intake and nutritional status of head and neck cancer (HNC) patients undergoing radiotherapy (RT) in China. [METHODS] This historical control study enrolled 139 HNC patients in the NC group and 146 patients in the control group. Before RT,...
Dietary intake; Head and neck cancer; Nutritional counseling; Nutritional status; Radiotherapy
0.456
28
Oncology; Oncology
Medicine; Nursing
2,022
35,571,576
Meat tenderizer assault and associated facial trauma: A case report.
Trauma case reports
Trauma Case Rep
39
null
10.1016/j.tcr.2022.100648
eng
2,022
6
null
2,022
4
27
[BACKGROUND] Blunt trauma to the face, head and neck is frequently encountered in violent assaults (Brink, 2009 [1]). There can be trauma to the cranium in high energy mechanisms, though interpersonal trauma is less likely to be associated with traumatic brain injury (TBI) (Salentijn et al., 2014 [2]). [CASE REPORT] We...
Blunt facial trauma; Facial trauma; Ocular injury; Zygomatic fracture; Zygomatic repair; Zygomaticomaxillary complex fracture
null
null
null
null
null
35,571,459
Association of the rs4646994 in ACE gene with susceptibility to tuberculosis in a region of the Brazilian Amazon.
Translational medicine communications
Transl Med Commun
7
1
10.1186/s41231-022-00116-6
eng
2,022
null
null
2,022
5
11
[BACKGROUND] Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis and represents an important global public health issue. Single-nucleotide polymorphisms and INDELs are common genetic variations that can be located in genes associated with immune response and, therefore, they ma...
ACE; INDEL; Polymorphisms; Susceptibility; Tuberculosis
null
null
null
null
null
35,571,447
Diagnostic yield of virtual bronchoscope navigation combined with radial endobronchial ultrasound guided transbronchial cryo-biopsy for peripheral pulmonary nodules: a prospective, randomized, controlled trial.
Annals of translational medicine
Ann Transl Med
10
8
10.21037/atm-22-1231
eng
2,022
4
null
null
null
null
[BACKGROUND] Transbronchial lung biopsy (TBLB) was a useful method for the diagnosis of peripheral pulmonary nodules (PPNs), but the smaller tissue samples obtained often could not meet the subsequent molecular pathological diagnosis. The purposes of this study were to assess the diagnostic yield of virtual bronchoscop...
Virtual bronchoscope navigation (VBN); peripheral pulmonary nodules (PPNs); radial endobronchial ultrasound (rEBUS); transbronchial cryo-biopsy (TBCB)
null
null
null
null
null
35,571,317
Immunohistochemical expression and evaluation of cyclin D1 and minichromosome maintenance 2 in oral squamous cell carcinoma and verrucous carcinoma.
Journal of oral and maxillofacial pathology : JOMFP
J Oral Maxillofac Pathol
26
1
10.4103/jomfp.jomfp_446_21
eng
2,022
null
null
2,022
3
31
[BACKGROUND] The study of cell proliferation is important for assessing the tumor behavior, prognosis and patient survival of oral carcinomas. As literature search did not reveal sufficient studies of immunohistochemical expression of cyclin D1 and minichromosome maintenance 2 (MCM2) in oral squamous cell carcinoma (OS...
Cell proliferation; cyclin D1; minichromosome maintenance 2; oral squamous cell carcinoma; verrucous carcinoma
0.329
43
Dentistry; Otorhinolaryngology; Pathology and Forensic Medicine
Dentistry; Medicine
2,022
35,570,608
Our Pediatric Liver and Kidney Transplant Activities in 2021.
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
Exp Clin Transplant
20
Suppl 3
10.6002/ect.PediatricSymp2022.O29
eng
2,022
5
null
null
null
null
[OBJECTIVES] In children with end-stage renal disease, chronic liver failure, or acute liver failure, liver transplant and kidney transplant are the most effective modalities for better clinical outcomes compared with other therapies. However, children are particularly susceptible to surgical complications, so pediatri...
null
0.257
37
Transplantation
Medicine
2,022
35,570,544
Anorectal Function with High-Resolution Anorectal Manometry in Active Ulcerative Colitis and after Remission: A Pilot Study.
Reviews on recent clinical trials
Rev Recent Clin Trials
17
2
10.2174/1574887117666220513110705
eng
2,022
null
null
null
null
null
[BACKGROUND] Ulcerative colitis may impair anorectal function, causing disabling symptoms such as incontinence and/or increase in the stool frequency, urgency and tenesmus. Data on anorectal function in these patients evaluated by conventional anorectal manometry are conflicting. [OBJECTIVES] The aim of this prospectiv...
HRAM; High-resolution anorectal manometry; Inflammatory bowel disease; Proctitis; Ulcerative colitis
null
null
null
null
null
35,570,366
Restorative angle of zirconia restorations cemented on non-original titanium bases influences the initial marginal bone loss: 5-year results of a prospective cohort study.
Clinical oral implants research
Clin Oral Implants Res
33
7
10.1111/clr.13954
eng
2,022
7
null
2,022
5
29
[AIM] To assess radiographic, restorative, clinical and technical outcomes as well as patient satisfaction of directly veneered zirconia restorations cemented on non-original titanium bases over 5 years. [MATERIAL AND METHODS] Twenty-four patients with a single missing tooth in the aesthetic zone were recruited. All pa...
CAD/CAM; dental implant-abutment design; dental implants; material testing; prosthodontics; titanium; zirconium
1.691
191
Oral Surgery
Dentistry
2,022
35,570,253
Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail Differently.
Clinical pharmacokinetics
Clin Pharmacokinet
61
7
10.1007/s40262-022-01119-0
eng
2,022
7
null
2,022
5
16
[BACKGROUND] Activities of hepatic cytochrome P450 enzymes (CYPs) are relevant for hepatic clearance of drugs and known to be decreased in patients with liver cirrhosis. Several studies have reported the effect of liver cirrhosis on CYP activity, but the results are partially conflicting and for some CYPs lacking. [OBJ...
null
1.238
191
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,569,920
RS1 gene is a novel prognostic biomarker for lung adenocarcinoma.
Thoracic cancer
Thorac Cancer
13
12
10.1111/1759-7714.14471
eng
2,022
6
null
2,022
5
15
[BACKGROUND] Although it has a poor prognosis, patients with lung adenocarcinoma (LUAD) have a relatively higher 5-year survival period. Thus, it is necessary to identify effective prognostic markers to evaluate the effect of early treatment. RS1 gene encodes retinoschisin, a key protein in congenital retinoschisis, wh...
LUAD; RS1; bioinformatics; prognosis
0.73
55
Medicine; Oncology; Pulmonary and Respiratory Medicine
Medicine
2,022
35,569,534
Long-term exposure to ambient air pollution is associated with an increased incidence and mortality of acute respiratory distress syndrome in a large French region.
Environmental research
Environ Res
212
Pt D
10.1016/j.envres.2022.113383
eng
2,022
9
null
2,022
5
12
[INTRODUCTION] Air pollution exposure is suspected to alter both the incidence and mortality in acute respiratory distress syndrome (ARDS). The impact of chronic air pollutant exposure on the incidence and mortality of ARDS from various aetiologies in Europe remains unknown. The main objective of this study was to eval...
Acute respiratory distress syndrome; Mortality; Nitrogen dioxide; Particulate matters; Pollution incidence
1.635
196
Biochemistry; Environmental Science
Biochemistry, Genetics and Molecular Biology; Environmental Science
2,022
35,569,516
Levonorgestrel 52 mg intrauterine system efficacy and safety through 8 years of use.
American journal of obstetrics and gynecology
Am J Obstet Gynecol
227
6
10.1016/j.ajog.2022.05.022
eng
2,022
12
null
2,022
5
13
[BACKGROUND] Extending hormonal intrauterine system duration will allow users to have less need for procedures to provide long-term contraception. [OBJECTIVE] This study aimed to evaluate the efficacy and safety of the levonorgestrel 52 mg intrauterine system during years 7 and 8 of use. [STUDY DESIGN] A total of 1751 ...
8 years; Liletta; amenorrhea; contraception; efficacy; intrauterine device; intrauterine system; levonorgestrel; safety
3.068
274
Obstetrics and Gynecology
Medicine
2,022
35,569,314
Post-operative haemorrhage secondary to cinnamon use. A case report.
International journal of surgery case reports
Int J Surg Case Rep
95
null
10.1016/j.ijscr.2022.107179
eng
2,022
6
null
2,022
5
10
[INTRODUCTION] Herbal medicine plays a significant role in modern medicine. The difficulty in integrating the two, lies in the unknown quantities of active ingredients in herbal remedies. This proved true in this clinical scenario. The quantity of coumarin, in the form of cinnamon ingested by this patient over ten mont...
Alternative medicine; Case report; Cinnamon; Coumarin; Postoperative haemorrhage; colon cancer
0.193
31
Surgery
Medicine
2,022
35,569,145
A 45-year follow-up study of adolescent schizophrenia. Part I: Premorbid values of psychological and relational indicators in the context of illness course and long-term social functioning of patients.
Psychiatria polska
Psychiatr Pol
56
1
10.12740/PP/OnlineFirst/125745
eng
2,022
2
27
2,022
2
27
[OBJECTIVES] Research on predictors of adolescent schizophrenia, especially those based on long-term follow-up studies, is rare in the literature. In our analysis, we examine the relationship between the premorbid functioning of the respondents and clinical and social indicators of the illness course. [METHODS] 69 pati...
adolescence; prognosis; schizophrenia
0.377
35
Medicine; Psychiatry and Mental Health
Medicine
2,022
35,569,096
Burden and risk factors of cutaneous leishmaniasis in Ethiopia: a systematic review and meta-analysis.
International journal of dermatology
Int J Dermatol
61
11
10.1111/ijd.16265
eng
2,022
11
null
2,022
5
15
[INTRODUCTION] Cutaneous leishmaniasis (CL) is a major public health problem in Ethiopia. About 30 million people are at risk, and there are 20,000 to 50,000 new cases annually. It is maintained by rock hyraxes and Phlebotomus sand flies. Different studies showed the presence and risk factors of CL. However, there is n...
null
0.623
111
Dermatology
Medicine
2,022
35,568,937
A standardized implementation of multicenter quality improvement program of very low birth weight newborns could significantly reduce admission hypothermia and improve outcomes.
BMC pediatrics
BMC Pediatr
22
1
10.1186/s12887-022-03310-5
eng
2,022
5
14
2,022
5
14
[BACKGROUND] Admission hypothermia (AH, 36.5℃) remains a major challenge for global neonatal survival, especially in developing countries. Baseline research shows nearly 89.3% of very low birth weight (VLBW, 1500 g) infants suffer from AH in China. Therefore, a prospective multicentric quality improvement (QI) initia...
Hypothermia; Neonates; Outcomes; Quality improvement; Very low birth weight
0.742
106
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,568,886
Association between delta anion gap and hospital mortality for patients in cardiothoracic surgery recovery unit: a retrospective cohort study.
BMC surgery
BMC Surg
22
1
10.1186/s12893-022-01625-9
eng
2,022
5
14
2,022
5
14
[BACKGROUNDS] High level of anion gap (AG) was associated with organic acidosis. This study aimed to explore the relationship between delta AG (ΔAG = AGmax - AGmin) during first 3 days after intensive care unit (ICU) admission and hospital mortality for patients admitted in the cardiothoracic surgery recovery unit (CSR...
Acid-basic disturbances; Anion gap; Cardiothoracic surgery; MIMIC III; Mortality
0.502
64
Surgery; Medicine
Medicine
2,022
35,568,880
Recycling industrial food wastes for lipid production by oleaginous yeasts Rhodosporidiobolus azoricus and Cutaneotrichosporon oleaginosum.
Biotechnology for biofuels and bioproducts
Biotechnol Biofuels Bioprod
15
1
10.1186/s13068-022-02149-3
eng
2,022
5
14
2,022
5
14
[BACKGROUND] Microbial lipids have been emerging as a sustainable alternative to vegetable oils and animal fat to produce biodiesel and industrial relevant chemicals. The use of wastes for microbial processes can represent a way for upgrading low value feedstock to high value products, addressing one of the main goals ...
Cutaneotrichosporon oleaginosum; Food waste; Microbial lipids; Oleaginous yeasts; Rhodosporidiobolus azoricus; Yeast biomass
null
null
null
null
null
35,568,875
Versatile aliphatic polyester biosynthesis system for producing random and block copolymers composed of 2-, 3-, 4-, 5-, and 6-hydroxyalkanoates using the sequence-regulating polyhydroxyalkanoate synthase PhaCAR.
Microbial cell factories
Microb Cell Fact
21
1
10.1186/s12934-022-01811-7
eng
2,022
5
14
2,022
5
14
[BACKGROUND] Polyhydroxyalkanoates (PHAs) are microbial polyesters synthesized by PHA synthases. Naturally occurring PHA copolymers possess a random monomer sequence. The development of PhaCAR, a unique sequence-regulating PHA synthase, has enabled the spontaneous biosynthesis of PHA block copolymers. PhaCAR synthesize...
2-Hydroxybutyrate; 4-Hydroxy-2-methylbutanoate; 5-Hydroxypentanoate; Biodegradable plastic; Block copolymer; PHA synthase; Sequence regulation
1.091
134
Applied Microbiology and Biotechnology; Bioengineering; Biotechnology
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Immunology and Microbiology
2,022
35,568,583
Quality of life after extended pelvic exenterations.
Gynecologic oncology
Gynecol Oncol
166
1
10.1016/j.ygyno.2022.04.022
eng
2,022
7
null
2,022
5
12
[BACKGROUND] The aim of the study was to compare health-related quality of life (QoL) and oncological outcome between gynaecological cancer patients undergoing pelvic exenteration (PE) and extended pelvic exenteration (EPE). EPEs were defined as extensive procedures including, in addition to standard PE extent, the res...
Gynaecological cancer; Health-related quality of life; LEER; Out-of-box procedures; Pelvic exenteration
1.674
192
Obstetrics and Gynecology; Oncology
Medicine
2,022
35,568,438
Clinical and histological findings at second but not at first kidney biopsy predict end-stage kidney disease in a large multicentric cohort of patients with active lupus nephritis.
Lupus science medicine
Lupus Sci Med
9
1
10.1136/lupus-2022-000689
eng
2,022
5
null
null
null
null
[OBJECTIVE] To investigate second kidney biopsy as predictor of end-stage kidney disease (ESKD) in active lupus nephritis (LN). [METHODS] Patients with biopsy-proven LN (International Society of Nephrology/Renal Pathology Society 2003) who had undergone a second kidney biopsy between January 1990 and December 2018 were...
Inflammation; Lupus Erythematosus, Systemic; Lupus Nephritis
null
null
null
null
null
35,568,433
Physical Activity Participation in People With an Active Diabetic Foot Ulceration: A Scoping Review.
Canadian journal of diabetes
Can J Diabetes
46
3
10.1016/j.jcjd.2021.07.002
eng
2,022
4
null
2,021
7
10
[BACKGROUND] Being physically active on a regular basis has a favourable impact on diabetes-related complications. With the exception of evidence advising individuals with an active diabetic foot ulceration (DFU) to avoid weight-bearing activity, no physical activity (PA) recommendations are currently provided for this...
activities of daily living; diabetic foot ulcer; exercice; exercise; physical activity; plaie plantaire; plantar wound; scoping review
0.723
59
Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,568,116
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Journal of ethnopharmacology
J Ethnopharmacol
294
null
10.1016/j.jep.2022.115360
eng
2,022
8
10
2,022
5
11
[ETHNOPHARMACOLOGICAL RELEVANCE] Jianpi Huayu decoction (JHD) is a traditional Chinese medicinal preparation used to treat a variety of malignant tumors including HCC, although the underlying mechanism remains unknown. Exosomes in the tumor microenvironment mediate intercellular signaling among cancer cells, but precis...
Epithelial mesenchymal transition; Exosome; Hepatocellular carcinoma; Jianpi huayu decoction; miR-23a-3p
0.833
243
Drug Discovery; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,022
35,567,908
What factors facilitate interprofessional collaboration outcomes in interprofessional education? A multi-level perspective.
Nurse education today
Nurse Educ Today
114
null
10.1016/j.nedt.2022.105393
eng
2,022
7
null
2,022
5
6
[OBJECTIVES] Interprofessional education (IPE) harnesses the power of teams to facilitate collaborative learning across disciplines. However, prior research has not paid sufficient attention to the role of team-level factors on IPE outcomes, posing a major theoretical and methodological limitation. In response to this,...
Interprofessional education; Multi-level analysis; Social interdependence theory
0.946
109
Education; Nursing
Nursing; Social Sciences
2,022
35,567,870
Influence of positive and negative symptoms on hedonic and eudaemonic well-being in people with schizophrenia: A longitudinal analysis from the EuroSc study.
Schizophrenia research
Schizophr Res
244
null
10.1016/j.schres.2022.04.009
eng
2,022
6
null
2,022
5
11
[BACKGROUND] Subjective well-being in people with schizophrenia is likely to be impaired by positive and negative psychotic symptoms. However, these may impact differentially on hedonic (satisfaction and interest in life) and eudaemonic (optimal psychological and social functioning) components. [AIMS] We hypothesized t...
Community mental health teams; Longitudinal studies; Schizophrenia; Structural equation modelling; Well-being
1.429
204
Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience
2,022
35,567,584
Which cava anastomotic techniques are optimal regarding immediate and short-term outcomes after liver transplantation: A systematic review of the literature and expert panel recommendations.
Clinical transplantation
Clin Transplant
36
10
10.1111/ctr.14681
eng
2,022
10
null
null
null
null
[BACKGROUND] It has long been debated whether cava anastomosis should be performed with the piggyback technique or cava replacement, with or without veno-venous bypass (VVB), with or without temporary portocaval shunt (PCS) in the setting of liver transplantation. [OBJECTIVES] To identify whether different cava anastom...
caval replacement; cavocavostomy; liver transplantation; piggyback technique; renal function; temporary portocaval shunt; venovenous bypass
0.842
90
Transplantation
Medicine
2,022
35,567,426
Activation of aldehyde dehydrogenase 2 protects ethanol-induced osteonecrosis of the femoral head in rat model.
Cell proliferation
Cell Prolif
55
6
10.1111/cpr.13252
eng
2,022
6
null
2,022
5
14
[OBJECTIVES] Osteonecrosis of the femoral head (ONFH) is a devastating disease characterized by destructive bone structures, enlarged adipocyte accumulation and impaired vascularization. The aldehyde dehydrogenase 2 (ALDH 2) is the limiting enzyme for ethanol metabolism with many physiological functions. The aim was in...
null
1.681
102
Cell Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,565,831
Prevalence of Micronutrient Deficiencies in Patients Hospitalized with COVID-19: An Observational Cohort Study.
Nutrients
Nutrients
14
9
10.3390/nu14091862
eng
2,022
4
29
2,022
4
29
[BACKGROUND] A higher risk for severe clinical courses of coronavirus disease 2019 (COVID-19) has been linked to deficiencies of several micronutrients. We therefore studied the prevalence of deficiencies of eight different micronutrients in a cohort of hospitalized COVID-19-patients. [METHODS] We measured admission se...
COVID-19; SARS-CoV-2; deficiency; hospital outcomes; micronutrients
1.291
243
Food Science; Nutrition and Dietetics
Agricultural and Biological Sciences; Nursing
2,022
35,565,318
PD-1+ T-Cells Correlate with Nerve Fiber Density as a Prognostic Biomarker in Patients with Resected Perihilar Cholangiocarcinoma.
Cancers
Cancers (Basel)
14
9
10.3390/cancers14092190
eng
2,022
4
27
2,022
4
27
[BACKGROUND AND AIMS] Perihilar cholangiocarcinoma (pCCA) is a hepatobiliary malignancy, with a dismal prognosis. Nerve fiber density (NFD)-a novel prognostic biomarker-describes the density of small nerve fibers without cancer invasion and is categorized into high numbers and low numbers of small nerve fibers (high vs...
cholangiocarcinoma; immune cells; immune checkpoint; liver cancer; nerve fiber density; tumor microenvironment
1.312
157
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,565,037
Achieving Minimum Standards for Infection Prevention and Control in Sierra Leone: Urgent Need for a Quantum Leap in Progress in the COVID-19 Era!
International journal of environmental research and public health
Int J Environ Res Public Health
19
9
10.3390/ijerph19095642
eng
2,022
5
6
2,022
5
6
[INTRODUCTION] Good Infection prevention and control (IPC) is vital for tackling antimicrobial resistance and limiting health care-associated infections. We compared IPC performance before (2019) and during the COVID-19 (2021) era at the national IPC unit and all regional (4) and district hospitals (8) in Sierra Leone....
Ebola; IPC programme; IPCAF; IPCAT; SORT IT; WASH; health care-associated infection; operational research; universal health coverage
0.828
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,022
35,562,819
Particulate matter in the workplace: effects of a mental models-based folder combined with a practical assignment.
BMC public health
BMC Public Health
22
1
10.1186/s12889-022-13362-y
eng
2,022
5
13
2,022
5
13
[BACKGROUND] With increasing knowledge on the adverse health effects of certain constituents of PM (particulate matter), such as silica, metals, insoluble ions, and black carbon, PM has been under the attention of work safety experts. Previously, we investigated the perceptions of blue-collar workers in highly exposed ...
Educational folder; Exposimeter; Particulate matter; Risk communication; Work safety
1.307
211
Public Health, Environmental and Occupational Health
Medicine
2,022
35,562,750
Identification of mutation patterns and circulating tumour DNA-derived prognostic markers in advanced breast cancer patients.
Journal of translational medicine
J Transl Med
20
1
10.1186/s12967-022-03421-8
eng
2,022
5
13
2,022
5
13
[BACKGROUND] The correlations between circulating tumour DNA (ctDNA)-derived genomic markers and treatment response and survival outcome in Chinese patients with advanced breast cancer (ABC) have not been extensively characterized. [METHODS] Blood samples from 141 ABC patients who underwent first-line standard treatmen...
Advanced breast cancer; Next generation sequencing; Survival outcomes; Tumor mutation burden; ctDNA fraction
1.544
153
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,562,690
Understanding the epidemiology, clinical characteristics, knowledge and barriers to treatment and prevention of malaria among returning international laborers in northern Vietnam: a mixed-methods study.
BMC infectious diseases
BMC Infect Dis
22
1
10.1186/s12879-022-07322-5
eng
2,022
5
13
2,022
5
13
[BACKGROUND] With the decline in local malaria transmission in Vietnam as a result of the National Malaria Control Program (NMCP) elimination activities, a greater focus on the importation and potential reintroduction of transmission are essential to support malaria elimination objectives. [METHODS] We conducted a mult...
Key populations; Malaria elimination; Malaria importation; Migration; Plasmodium falciparum; Plasmodium malariae; Plasmodium ovale; Plasmodium vivax; Population movement; Vietnam
1.055
137
Infectious Diseases
Medicine
2,022
35,562,632
Ischemic stroke following corrective surgery for idiopathic scoliosis in a pediatric patient: the importance of early diagnosis.
Spine deformity
Spine Deform
10
5
10.1007/s43390-022-00516-6
eng
2,022
9
null
2,022
5
14
[PURPOSE] To present a rare case of a cerebral ischemic lesion of unknown etiology in a pediatric patient following idiopathic scoliosis surgery and to review the current literature regarding this complication in children. [METHODS] A 12-year-old female with early-onset scoliosis underwent surgery to correct a 65.6º sc...
Cerebrovascular accident; Idiopathic scoliosis; Ischemic stroke; Neurologic symptoms; Pediatrics; Postoperative complications; Risk factors; Spine surgery
0.726
41
Orthopedics and Sports Medicine
Medicine
2,022
35,562,627
Association between cardiovascular risk factors and left ventricular strain distribution in patients without previous cardiovascular disease.
Journal of echocardiography
J Echocardiogr
20
4
10.1007/s12574-022-00576-7
eng
2,022
12
null
2,022
5
13
[BACKGROUND] Some cardiovascular (CV) risk factors, such as hypertension and diabetes mellitus, have been reported to reduce left ventricular (LV) longitudinal strain (LS) even in patients with preserved LV ejection fraction. We hypothesized that multiple CV risk factors might cause changes in myocardial strain. Our st...
Echocardiography; Risk factors; Strain; Systolic function
0.403
21
Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,562,035
Early career opportunities and practice characteristics of recent graduates of shoulder and elbow fellowship programs.
Journal of shoulder and elbow surgery
J Shoulder Elbow Surg
31
9
10.1016/j.jse.2022.04.010
eng
2,022
9
null
2,022
5
11
[BACKGROUND] There exists anecdotal evidence that influential faculty members actively dissuade orthopedic surgery residents from pursuing a fellowship in shoulder and elbow due to a perceived lack of availability of jobs following graduation. The aims of the present study are to evaluate whether this perception is tru...
ASES fellowship; Shoulder and elbow fellowship; career opportunities; job satisfaction; practice characteristics
1.666
178
Medicine; Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,022
35,562,009
Vaginal progesterone compared with intramuscular 17-alpha-hydroxyprogesterone caproate for prevention of recurrent preterm birth in singleton gestations: a systematic review and meta-analysis.
American journal of obstetrics gynecology MFM
Am J Obstet Gynecol MFM
4
5
10.1016/j.ajogmf.2022.100658
eng
2,022
9
null
2,022
5
10
[OBJECTIVE] Randomized trials have found benefits of both vaginal progesterone and 17-alpha-hydroxyprogesterone caproate in the prevention of recurrent preterm birth. A previous meta-analysis directly comparing the two was limited by low-quality evidence, and national and international society guidelines remain conflic...
17-alpha-hydroxyprogesterone caproate; meta-analysis; prematurity; preterm birth prevention; progesterone; spontaneous preterm birth; systematic review; transvaginal ultrasound; ultrasound cervical length
null
null
null
null
null
35,561,519
Scoring of brain magnetic resonance imaging and neurodevelopmental outcomes in infants with congenital heart disease.
Early human development
Early Hum Dev
169
null
10.1016/j.earlhumdev.2022.105574
eng
2,022
6
null
2,022
4
25
[BACKGROUND] Advances in surgical techniques to tackle critical congenital heart diseases (CHD) have enhanced the survival rates and life expectancy of children born with heart disease. Studies to better acknowledge their neurodevelopmental trajectory have paramount implications. [OBJECTIVE] The aim of this study is to...
CHD; MRI; Neonates; Neurodevelopment
0.701
115
Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine
2,022
35,560,560
Aberrant static and dynamic functional network connectivity in heart failure with preserved ejection fraction.
ESC heart failure
ESC Heart Fail
9
4
10.1002/ehf2.13967
eng
2,022
8
null
2,022
5
13
[AIMS] Heart failure may lead to brain functional alterations related to cognitive impairment. This study aimed to detect alterations of static functional network connectivity (FNC) and dynamic FNC in heart failure with preserved ejection fraction (HFpEF) and to estimate the association between the altered FNC and clin...
Functional network connectivity; Heart failure; Resting-state fMRI
0.899
57
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,560,260
Cervical cancer prevention in Africa: A policy analysis.
Journal of cancer policy
J Cancer Policy
32
null
10.1016/j.jcpo.2021.100321
eng
2,022
6
null
2,022
1
1
[BACKGROUND] Cervical cancer is a major public health challenge in Africa. We analyzed the presence and content of policies for the primary, secondary and tertiary prevention of cervical cancer in Africa, to identify areas of opportunity for policy strengthening in the region most affected by cervical cancer globally. ...
Africa; Cervical cancer; HPV vaccine; Policy; Prevention
0.576
23
Health Policy; Oncology
Medicine
2,022
35,560,086
Characterizing Spatial Signatures of Gastric Electrical Activity Using Biomagnetic Source Localization.
IEEE transactions on bio-medical engineering
IEEE Trans Biomed Eng
69
11
10.1109/TBME.2022.3174847
eng
2,022
11
null
2,022
10
19
[BACKGROUND] The motility patterns in the gastrointestinal tract are regulated, in part, by bioelectrical events known as slow waves (SWs). Understanding temporal and spatial features of gastric SWs can help reveal the underlying causes of functional motility disorders. [OBJECTIVE] This study investigated the ability o...
null
null
null
null
null
null
35,559,864
Implications of dysregulated endogenous cannabinoid family members in the pathophysiology of endometriosis.
FS science
F S Sci
2
4
10.1016/j.xfss.2021.09.005
eng
2,021
11
null
2,021
10
6
[OBJECTIVE] To determine the involvement of the endocannabinoid (EC) family member in the pathophysiology of endometriosis (EMS). [DESIGN] Mass spectrometry analysis of plasma and tissue samples from patients with EMS, controls, and a mouse model of EMS and messenger RNA and immunohistochemistry analysis of the samples...
Endometriosis; endocannabinoids; hyperalgesia; inflammation
null
null
null
null
null
35,559,648
Understanding Baseline Physical Activity in Cardiac Rehabilitation Enrollees Using Mobile Health Technologies.
Circulation. Cardiovascular quality and outcomes
Circ Cardiovasc Qual Outcomes
15
7
10.1161/CIRCOUTCOMES.122.009182
eng
2,022
7
null
2,022
5
13
[BACKGROUND] Baseline physical activity in patients when they initiate cardiac rehabilitation is poorly understood. We used mobile health technology to understand baseline physical activity of patients initiating cardiac rehabilitation within a clinical trial to potentially inform personalized care. [METHODS] The VALEN...
cardiac rehabilitation; cardiovascular disease; exercise; mortality; risk; secondary prevention
null
null
null
null
null
35,559,399
The effects of vasopressin injection technique on ovarian reserve in laparoscopic cystectomy of bilateral ovarian endometrioma: a retrospective cohort study.
American journal of translational research
Am J Transl Res
14
4
null
eng
2,022
null
null
2,022
4
15
[OBJECTIVE] To evaluate the effects of vasopressin injection technique (VIT) on ovarian reserve in laparoscopic cystectomy of bilateral ovarian endometrioma. [MATERIAL AND METHODS] A total of 122 patients with bilateral ovarian endometrioma undergoing laparoscopic cystectomy were assigned to control or the VIT group. C...
Laparoscope; cystectomy; endometriosis; ovarian reserve
null
null
null
null
null
35,559,335
The Optimal Dose of Intraoperative Dexmedetomidine for Antiemetic Effects of Post-operative Nausea and Vomiting in Patients Undergoing Elective Thoracic Surgery: A Retrospective Cohort Study.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.891096
eng
2,022
null
null
2,022
4
26
[BACKGROUND] Dexmedetomidine (DEX) administration decreases post-operative nausea and vomiting (PONV), but it is a lack of large-scale retrospective cohort study and is unclear whether there is a dose-relationship and optimal dose for antiemetic effects between DEX and PONV. We performed a large-scale retrospective coh...
dexmedetomidine; optimal dose; post-operative nausea and vomiting; retrospective cohort; thoracic surgery
0.926
102
Medicine
Medicine
2,022
35,558,667
Effect of different surface treatments of presintered or sintered zirconia on bond strength to dentine.
Journal of conservative dentistry : JCD
J Conserv Dent
24
6
10.4103/jcd.jcd_249_21
eng
2,021
null
null
2,022
4
1
[AIM] To compare the effect of different zirconia surface treatments on cement bond strength to dentine. [MATERIALS AND METHODS] Stick-shaped pre-sintered zirconia (N = 128) were prepared and divided into eight groups (n = 16). Three surface treatments (sandblasting, neodymium-doped yttrium aluminum garnet [Nd:YAG] or ...
Dental ceramics; lasers; resin cement; shear bond; yttria-stabilized tetragonal zirconia
null
null
null
null
null
35,558,385
Endocardial Radiofrequency Ablation vs. Septal Myectomy in Patients With Hypertrophic Obstructive Cardiomyopathy: A Systematic Review and Meta-Analysis.
Frontiers in surgery
Front Surg
9
null
10.3389/fsurg.2022.859205
eng
2,022
null
null
2,022
4
26
[BACKGROUND] Septal myectomy (SM) has been the gold standard therapy for most patients with hypertrophic obstructive cardiomyopathy (HOCM). Endocardial radiofrequency ablation of septal hypertrophy (ERASH) is a novel treatment for septal reduction. We aimed to assess the efficacy and safety between two treatment strate...
endocardial radiofrequency ablation; hypertrophic obstructive cardiomyopathy; meta-analysis; septal myectomy; systematic review
0.459
48
Surgery
Medicine
2,022
35,585,890
Delayed acute subdural hematoma treated with endoscopic procedure: A case report.
Surgical neurology international
Surg Neurol Int
11
null
10.25259/SNI_529_2020
eng
2,020
null
null
2,020
10
21
[BACKGROUND] Delayed acute subdural hematoma (DASDH) is defined as late onset ASDH with the absence of any abnormal radiological and clinical findings at initial examination. Moreover, this entity is very rare in traumatic brain injury and its mechanism is still unclear. Recently, endoscopic surgery for ASDH has also b...
Bleeding source; Delayed acute subdural hematoma; Endoscopic procedure; Mechanism of bleeding
0.433
48
Neurology; Surgery
Medicine
2,020
35,559,743
Increased CXCL12 expression in endometrium of women with abnormal uterine bleeding is post-transcriptionally mediated via miR-23b-3p and is associated with decreased expression of the miR-23b-3p/24-3p/27b-3p cluster: a pilot study.
FS science
F S Sci
1
1
10.1016/j.xfss.2020.06.004
eng
2,020
8
null
2,020
7
2
[OBJECTIVE] To study C-X-C motif chemokine 12 (CXCL12) and CXCR4 expression in endometrial tissue from both women with and without abnormal uterine bleeding (AUB) of endometrial origin and evaluate their relationship with microRNA (miRNA). [DESIGN] Retrospective and laboratory study. [SETTING] University-based research...
Abnormal uterine bleeding; CXCL12; CXCR4; SDF-1; miR-23b-3p; miRNA
null
null
null
null
null
35,617,207
Plasma MicroRNAs as noninvasive diagnostic biomarkers in patients with Brugada syndrome.
PloS one
PLoS One
17
5
10.1371/journal.pone.0261390
eng
2,022
null
null
2,022
5
26
[BACKGROUND] Brugada syndrome (BrS) can be diagnosed by a type 1 BrS tracing in a 12-lead electrocardiogram (ECG). However, there are daily variations in the ECGs of BrS patients, which presents a challenge when diagnosing BrS. Although many susceptibility genes have been identified, the SCN5A gene is reportedly the ma...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
35,616,942
Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial.
JAMA network open
JAMA Netw Open
5
5
10.1001/jamanetworkopen.2022.13875
eng
2,022
5
2
2,022
5
2
[IMPORTANCE] Developing interventions against age-related memory decline and for older adults experiencing neurodegenerative disease is one of the greatest challenges of our generation. Spermidine supplementation has shown beneficial effects on brain and cognitive health in animal models, and there has been preliminary...
null
4.108
154
Medicine
Medicine
2,022
35,616,938
SARS-CoV-2 Attack Rate and Population Immunity in Southern New England, March 2020 to May 2021.
JAMA network open
JAMA Netw Open
5
5
10.1001/jamanetworkopen.2022.14171
eng
2,022
5
2
2,022
5
2
[IMPORTANCE] In emergency epidemic and pandemic settings, public health agencies need to be able to measure the population-level attack rate, defined as the total percentage of the population infected thus far. During vaccination campaigns in such settings, public health agencies need to be able to assess how much the ...
null
4.108
154
Medicine
Medicine
2,022
35,616,759
Gene identification and functional analysis of a D-type cyclin (CCND2) in freshwater pearl mussel (Hyriopsis cumingii).
Molecular biology reports
Mol Biol Rep
49
7
10.1007/s11033-022-07501-2
eng
2,022
7
null
2,022
5
26
[BACKGROUND] Cyclin D (CCND) plays an important role in the cell cycle and is a rate-limiting factor that facilitates the G1/S transition. [METHODS] In this study, the full-length cDNA of Hc-CCND2 was isolated from freshwater pearl mussel (Hyriopsis cumingii; Hc) and amplified using the 3´/5´ RACE system. The Hc-CCND2 ...
Cell cycle; Hc-CCND2; Hyriopsis cumingii; Overexpression; RNA interference
0.578
96
Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,616,725
Clinical features and visual outcomes of ocular sarcoidosis at a tertiary referral center in Tokyo.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Graefes Arch Clin Exp Ophthalmol
260
10
10.1007/s00417-022-05701-x
eng
2,022
10
null
2,022
5
26
[BACKGROUND] To analyze clinical features, treatment, complications, and visual outcomes of ocular sarcoidosis at a tertiary center in Tokyo. [METHODS] Clinical records of 53 patients with ocular sarcoidosis ("definite" or "presumed") presenting between 2013 and 2018 to the Kyorin Eye Center were retrospectively review...
Sarcoidosis; Uveitis; Visual prognosis
null
null
null
null
null
35,616,102
Multiplex Fragment Analysis for Flexible Detection of All SARS-CoV-2 Variants of Concern.
Clinical chemistry
Clin Chem
68
8
10.1093/clinchem/hvac081
eng
2,022
7
27
null
null
null
[BACKGROUND] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continue to emerge, and effective tracking requires rapid return of results. Surveillance of variants is typically performed by whole genome sequencing (WGS), which can be financially prohibitive and requires specialized equipment and bi...
null
1.536
248
Biochemistry; Clinical Biochemistry; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,615,971
Fostering collaborative learning and leadership through near-peer mentorship among undergraduate nursing students.
Nursing forum
Nurs Forum
57
5
10.1111/nuf.12755
eng
2,022
9
null
2,022
5
26
[BACKGROUND] Innovative teaching strategies in nursing education are essential with increasing enrollment. Collaborative learning and leadership (CLL) activities encourage near-peer learning through mentorship between senior-level and novice students while supporting teaching ratios in lab and clinical. In this study, ...
Near-peer mentoring; nursing education; peer mentor behaviors; teaching strategies
0.686
56
Nursing
Nursing
2,022
35,615,820
Mental Health Status of Migrant Nepalese Workers Rescued By Government of Nepal During the Corona Virus disease -19 Pandemic.
Journal of Nepal Health Research Council
J Nepal Health Res Counc
19
4
10.33314/jnhrc.v19i04.3552
eng
2,022
3
13
2,022
3
13
[BACKGROUND] The corona virus pandemic rapidly sweeps across the world; it is inducing a considerable degree of depression, stress and anxiety concern in the population at large and among certain groups in particular, such as migrant workers. The aim of the study is to find out mental health status of migrant workers r...
null
0.259
23
Medicine
Medicine
2,022
35,615,790
Differential malondialdehyde (MDA) detection in plasma samples of patients with major depressive disorder (MDD): A potential biomarker.
The Journal of international medical research
J Int Med Res
50
5
10.1177/03000605221094995
eng
2,022
5
null
null
null
null
[OBJECTIVE] To measure plasma levels of malondialdehyde (MDA), a marker of oxidative stress (OS), in patients with major depressive disorder (MDD) compared with healthy control (HC) subjects in order to determine if it is a possible biomarker of depression. [METHODS] This prospective cross-sectional study enrolled pati...
Major depressive disorder (MDD); malondialdehyde (MDA); oxidative stress; plasma biomarker
0.393
74
Biochemistry; Biochemistry; Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,615,781
European Academy of Neurology 2019 - 2022.
European journal of neurology
Eur J Neurol
29
9
10.1111/ene.15421
eng
2,022
9
null
2,022
6
24
[BACKGROUND] The EAN was founded in 2014 with the mission of reducing the burden of neurological disorders. [METHODS] In 2019 the society defined four strategic priorities: education, science, membership, and advocacy. This paper reviews the EAN development in the last 3 years. [RESULTS] The outbreak of COVID-19 pandem...
Burden; COVID-19; EAN; Ukraine; brain health; diversity; education; general neurology; neurological disorders; science; students; tele-neurology; training; war
1.554
151
Neurology; Neurology
Medicine; Neuroscience
2,022
35,615,442
Association Between Triglyceride Glucose Index-Waist Circumference and Risk of First Myocardial Infarction in Chinese Hypertensive Patients with Obstructive Sleep Apnoea: An Observational Cohort Study.
Nature and science of sleep
Nat Sci Sleep
14
null
10.2147/NSS.S362101
eng
2,022
null
null
2,022
5
19
[PURPOSE] This study aimed to investigate the association between triglyceride glucose index-waist circumference (TyG-WC) and the risk of first myocardial infarction (MI) in Chinese hypertensive patients with obstructive sleep apnoea (OSA). [METHODS] This study was an observational cohort study. A total of 2224 Chinese...
cohort study; hypertension; myocardial infarction; obstructive sleep apnoea; triglyceride glucose index-waist circumference
0.875
55
Applied Psychology; Behavioral Neuroscience
Neuroscience; Psychology
2,022
35,615,389
Morscher's femoral neck lengthening osteotomy through surgical hip dislocation approach for preservation of Perthes and Perthes-like deformities.
Journal of children's orthopaedics
J Child Orthop
16
1
10.1177/18632521221080477
eng
2,022
2
null
2,022
4
5
[BACKGROUND] Typical sequelae of Perthes disease and Perthes-like deformities comprise a short femoral neck, aspherical femoral head, and greater trochanteric overgrowth. Morscher's osteotomy aims at restoring the normal extra-articular anatomy, but incapable of restoring a normal head-neck contour with residual imping...
Perthes disease; Perthes-like deformity; femoral neck lengthening; surgical hip dislocation; treatment
0.573
54
Orthopedics and Sports Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,022
35,615,333
Impact of Superoxide Dismutase Genetic Polymorphism (SOD2 Val16Ala) and Superoxide Dismutase Level on Disease Severity in a Cohort of Egyptian Sickle Cell Disease Patients.
Mediterranean journal of hematology and infectious diseases
Mediterr J Hematol Infect Dis
14
1
10.4084/MJHID.2022.037
eng
2,022
null
null
2,022
5
1
[BACKGROUND] Oxidative stress plays a pivotal role in the pathophysiology of sickle cell disease (SCD) and its associated disease complications. Superoxide Dismutases (SODs) are protective enzymes against oxidative stress. SOD2 deficiency results in the accumulation of oxidized red cell proteins, increased rate of hemo...
Egypt; SCD; SOD2; rs4880
0.614
44
Infectious Diseases; Hematology
Medicine
2,022
35,615,098
Serum Metabolomics Benefits Discrimination Kidney Disease Development in Type 2 Diabetes Patients.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.819311
eng
2,022
null
null
2,022
5
9
[BACKGROUND] Diabetic kidney disease (DKD) is the primary cause of end-stage renal disease, raising a considerable burden worldwide. Recognizing novel biomarkers by metabolomics can shed light on new biochemical insight to benefit DKD diagnostics and therapeutics. We hypothesized that serum metabolites can serve as bio...
biomarker discovery; diabetic kidney disease; metabolomics; progression; proteinuria
0.926
102
Medicine
Medicine
2,022
35,615,072
Complement-Amplifying Conditions in Atypical Hemolytic Uremic Syndrome: A Canadian Case Series.
Canadian journal of kidney health and disease
Can J Kidney Health Dis
9
null
10.1177/20543581221100288
eng
2,022
null
null
2,022
5
19
[RATIONALE] Thrombotic microangiopathies (TMAs) are systemic disorders that often affect the kidneys and encompass a heterogeneous group of conditions, including atypical hemolytic uremic syndrome (aHUS). The complement pathway is thought to play a crucial role in the pathogenesis of aHUS, and a favorable response can ...
complement pathway; hemolytic uremic syndrome; organ dysfunction; thrombotic microangiopathy; thrombotic thrombocytopenic purpura
0.701
37
Nephrology
Medicine
2,022
35,614,889
Fraction from Calliandra portoricensis reduces 7, 12 dimethylbenz(a)anthracene-induced mammary tumors in Wistar rats.
Avicenna journal of phytomedicine
Avicenna J Phytomed
12
2
10.22038/AJP.2021.18641
eng
2,022
null
null
null
null
null
[OBJECTIVE] Calliandra portoricensis (CP) is used in Nigeria for the treatment of breast diseases. We investigated the effects of fraction from CP on 7, 12-dimethylbenz(a)anthracene (DMBA)-induced mammary gland tumors. [MATERIALS AND METHODS] Female Wistar rats (40) were allotted into five equal groups. Group 1 served ...
Apoptosis
null
null
null
null
null
35,613,998
Alliance A082002 -a randomized phase II/III trial of modern immunotherapy-based systemic therapy with or without SBRT for PD-L1-negative, advanced non-small cell lung cancer.
Clinical lung cancer
Clin Lung Cancer
23
5
10.1016/j.cllc.2022.04.004
eng
2,022
7
null
2,022
4
30
[INTRODUCTION] Treatment of advanced stage non-small cell lung cancer (NSCLC) has changed dramatically due to immunotherapy. However, patients without Programmed Death-Ligand 1 (PD-L1) protein expression often benefit less from immunotherapy. This trial is designed to test if stereotactic body radiation therapy (SBRT) ...
Chemotherapy; Immunotherapy; Lung cancer; Stereotactic body radiation therapy; advanced stage non-small cell lung cancer; programmed death-1 ligand negative
1.137
78
Pulmonary and Respiratory Medicine; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,613,718
Preoperative stoma site marking for fecal diversions (ileostomy and colostomy): position statement of the Canadian Society of Colon and Rectal Surgeons and Nurses Specialized in Wound, Ostomy and Continence Canada.
Canadian journal of surgery. Journal canadien de chirurgie
Can J Surg
65
3
10.1503/cjs.022320
eng
2,022
null
null
2,022
5
25
[BACKGROUND] Every year, about 13 000 Canadians undergo an ostomy procedure, which requires stoma site marking to create a well-constructed stoma and prevent stoma-related complications. The Canadian Society of Colon and Rectal Surgeons (CSCRS) and Nurses Specialized in Wound, Ostomy and Continence Canada (NSWOCC) crea...
null
null
null
null
null
null
35,613,486
Experiences of midwives and nurses when implementing abortion policies: A systematic integrative review.
Midwifery
Midwifery
111
null
10.1016/j.midw.2022.103363
eng
2,022
8
null
2,022
5
11
[INTRODUCTION] Policy implementation can be affected by what individuals believe to be right and wrong. When implementing abortion policies, providers' moral beliefs can be relevant in the success of the implementation process. Considering that midwives and nurses are direct providers of abortion care, exploring their ...
Health policy; Induced abortion; Midwifery; Nursing; Systematic review
0.921
91
Maternity and Midwifery; Obstetrics and Gynecology
Medicine; Nursing
2,022
35,613,466
Loneliness Among Rural Self-Management Education Program Enrollees During the COVID-19 Pandemic.
American journal of health promotion : AJHP
Am J Health Promot
36
8
10.1177/08901171221105265
eng
2,022
11
null
2,022
5
25
[PURPOSE] Pandemic-related isolation may exacerbate loneliness among rural adults; we sought to characterize loneliness and associated factors among rural adults during the COVID-19 pandemic. [DESIGN] Cross-sectional observational study. [SETTING] Remotely delivered self-management education (SME) workshops, rural upst...
COVID-19; adults; health communications; internet; loneliness; mental health; rural health; social support
0.889
103
Health; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,022
35,613,244
Bio-Exercise (BioEx) - A biocreative orofacial myofunctional therapy: preliminary cephalometric study and clinical application.
Dental press journal of orthodontics
Dental Press J Orthod
27
2
10.1590/2177-6709.27.2.e2220367.oar
eng
2,022
null
null
2,022
5
23
[OBJECTIVE] To introduce newly structured and developed orofacial myofunctional therapy (OFMFT) protocols named Bio-Exercise (BioEx), and evaluate the treatment effect of this method, using lateral cephalometric analysis on malocclusion with low tongue posture in young patients. [METHODS] A retrospective preliminary st...
null
null
null
null
null
null
35,613,208
Measuring optic nerve sheath diameter using ultrasonography in patients with idiopathic intracranial hypertension.
Arquivos de neuro-psiquiatria
Arq Neuropsiquiatr
80
6
10.1590/0004-282X-ANP-2021-0136
eng
2,022
6
null
null
null
null
[BACKGROUND] Idiopathic intracranial hypertension (IIH) is primarily a disorder of obese young women characterized by symptoms associated with raised intracranial pressure in the absence of a space-occupying lesion. [OBJECTIVE] To compare the mean optic nerve sheath diameter (ONSD) measured using ultrasonography (USG) ...
null
0.391
60
Neurology; Neurology; Biological Psychiatry
Medicine; Neuroscience
2,022
35,613,099
Worldwide suicide mortality trends by firearm (1990-2019): A joinpoint regression analysis.
PloS one
PLoS One
17
5
10.1371/journal.pone.0267817
eng
2,022
null
null
2,022
5
25
[INTRODUCTION] Suicide by firearm is a major public health problem in many countries. But, studies that investigated the mortality of suicide by firearm on a global scale are still limited. The aim of this study was to assess the global, regional and national trends in mortality of suicide by firearm from 1990 to 2019....
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
35,612,778
Analysis of genetic diversity among Onobrychis accessions with high agronomic performance by simple sequence repeat (SSR) markers.
Molecular biology reports
Mol Biol Rep
49
6
10.1007/s11033-022-07584-x
eng
2,022
6
null
2,022
5
25
[BACKGROUND] Onobrychis viciifolia Scop. is a short-lived perennial cool-season legume used for forage production. It is a common native species in Asia Minor, especially in Turkey, the districts of the Caucasus, and the Caspian fringes. It can grow well in a broad range of climatic and soil types found in Asia, Europe...
Genetic diversity; Microsatellites; Onobrychis; STRUCTURE; UPGMA
0.578
96
Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,612,697
Uptake of lipid core nanoparticles by fragments of tissues collected during cerebral tumor excision surgeries: hypotheses for use in drug targeting therapy.
Journal of neuro-oncology
J Neurooncol
158
3
10.1007/s11060-022-04028-1
eng
2,022
7
null
2,022
5
25
[PURPOSE] Malignant cerebral tumors have poor prognosis and the blood-brain barrier is a major hindrance for most drugs to reach those tumors. Lipid nanoparticles (LDE) that bind to lipoprotein receptors may carry anticancer drugs and penetrate the cells through those receptors that are overexpressed in gliomas. The ai...
Glioma treatment; LDL-receptor and cancer; Nanoemulsions; Solid lipid nanoparticles
1.178
141
Neurology; Neurology; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,022