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35,648,221
CircPVT1 promotes the tumorigenesis and metastasis of osteosarcoma via mediation of miR-26b-5p/CCNB1 axis.
Journal of bone and mineral metabolism
J Bone Miner Metab
40
4
10.1007/s00774-022-01326-6
eng
2,022
7
null
2,022
6
1
[INTRODUCTION] Osteosarcoma (OS) is the most aggressive malignancy among the bone tumors in the world. Circular RNAs (circRNAs) have been reported to be participated in multiple cancers, including OS. Meanwhile, circPVT1 has been proved to be upregulated in OS. However, the mechanism by which circPVT1 mediates the tumo...
CCNB1; CircPVT1; Metastasis; MiR-26b-5p; Osteosarcoma
0.748
88
Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine; Orthopedics and Sports Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,648,117
Cognitive Predictors of Social Interaction in Daily Contexts Among Children With Autism Spectrum Disorder.
The American journal of occupational therapy : official publication of the American Occupational Therapy Association
Am J Occup Ther
76
3
10.5014/ajot.2022.042556
eng
2,022
5
1
null
null
null
[IMPORTANCE] Theory of mind (ToM) and executive function (EF) are often used to explain social interaction deficits in children with autism spectrum disorder (ASD), but no behavioral studies have specifically examined their relationship. [OBJECTIVE] To investigate the cognitive correlates of social interaction in daily...
null
null
null
null
null
null
35,647,828
Serum 25-hydroxyvitamin D correlates with endometrial HOXA10 mRNA expression.
European review for medical and pharmacological sciences
Eur Rev Med Pharmacol Sci
26
10
10.26355/eurrev_202205_28842
eng
2,022
5
null
null
null
null
[OBJECTIVE] Endocrine Society classified patients with serum 25-hydroxyvitamin D [25(OH)D] levels below 20 ng/ml as deficiency, 20-30 ng/ml as insufficiency, and >30 ng/ml as replete. This study was planned to investigate the relationship between serum vitamin D level and homeobox 10 mRNA expression in women with polyc...
null
null
null
null
null
null
35,647,609
Insights into the molecular triggers of parosmia based on gas chromatography olfactometry.
Communications medicine
Commun Med (Lond)
2
null
10.1038/s43856-022-00112-9
eng
2,022
null
null
2,022
5
24
[BACKGROUND] Parosmia is a debilitating condition in which familiar smells become distorted and disgusting, with consequences for diet and mental health. It is a feature of post-infectious olfactory loss, particularly resulting from COVID-19. There is currently little understanding of its pathophysiology, and the preva...
Brain injuries; Central nervous system infections; Chemical biology; Health sciences; Olfactory receptors
null
28
Assessment and Diagnosis; Epidemiology; Internal Medicine; Medicine; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,022
35,647,569
"When my children see their father is sober, they are happy": A qualitative exploration of family system impacts following men's engagement in an alcohol misuse intervention in peri-urban Kenya.
SSM. Mental health
SSM Ment Health
1
null
10.1016/j.ssmmh.2021.100019
eng
2,021
12
null
2,021
9
16
[BACKGROUND] Men's alcohol misuse does not occur in a vacuum but has a cascade of consequences for families and children, with ties to violence, poor parenting, and poor partner and child mental health. Despite the intersection of individual and interpersonal problems associated with men's alcohol use, studies explorin...
Alcohol intervention; Family outcomes; Fathers; Global mental health; Kenya; Therapeutic change
null
18
Psychology; Social Sciences
Psychology; Social Sciences
2,021
35,647,387
Which mother-headed households' parenting styles are related to children's behavior problems? A cross-sectional study.
Journal of preventive medicine and hygiene
J Prev Med Hyg
63
1
10.15167/2421-4248/jpmh2022.63.1.2382
eng
2,022
3
null
2,022
4
26
[INTRODUCTION] Parenting styles are considered as one of the main determinants of individual and social behaviors and the use of dysfunctional styles can create child behavioral problems. The aim of this study was to determine the relationship between mother-child relationship patterns in mother-headed households and c...
Behavior problems; Children; Mothers; Parenting style
0.405
40
Infectious Diseases; Public Health, Environmental and Occupational Health
Medicine
2,022
35,647,213
Clinical Outcomes After Suture Tape Augmentation for Ankle Instability: A Systematic Review.
Orthopaedic journal of sports medicine
Orthop J Sports Med
10
5
10.1177/23259671221095791
eng
2,022
5
null
2,022
5
24
[BACKGROUND] There is minimal literature on the use of suture tape augmentation in the treatment of chronic lateral ankle instability (CLAI), prompting an investigation on its use and effect during surgery of the lateral ankle. [PURPOSE] To evaluate the evidence for the use of suture tape augmentation in the treatment ...
ankle sprain; chronic lateral ankle instability; lateral ankle; suture tape
1.113
68
Orthopedics and Sports Medicine
Medicine
2,022
35,647,174
Dynamic navigation system-guided trans-inferior alveolar nerve implant placement in the atrophic posterior mandible: A case report.
World journal of clinical cases
World J Clin Cases
10
12
10.12998/wjcc.v10.i12.3907
eng
2,022
4
26
null
null
null
[BACKGROUND] In atrophic posterior mandibular areas, where the bone height superior to the inferior alveolar nerve (IAN) is less than 6 mm, short implants are not applicable. Conventional alternatives such as IAN transposition and various alveolar bone augmentation approaches are technically demanding and prone to comp...
Case report; Dental implant; Dynamic navigation system; Inferior alveolar nerve; Insufficient bone height; Posterior mandible
null
38
Medicine
Medicine
2,022
35,646,447
Association of Flame-Retardant Clothing With Mycosis Fungoides: A Retrospective Analysis.
Dermatology practical & conceptual
Dermatol Pract Concept
12
2
10.5826/dpc.1202a91
eng
2,022
5
null
2,022
4
1
[INTRODUCTION] Mycosis fungoides (MF), the most prevalent form of cutaneous T-cell lymphoma (CTCL), has been associated with a variety of environmental and occupational exposures. Flame-retardant clothing (FRC), in contrast to flame-resistant clothing, is chemically treated and may constitute a previously unrecognized ...
cutaneous T-cell lymphoma; flame-retardant chemicals; flame-retardant clothing; mycosis fungoides; occupational-related exposure
null
null
null
null
null
35,646,361
Burden, risk factors, and management of neutropenic fever among solid cancer patients in Ethiopia.
SAGE open medicine
SAGE Open Med
10
null
10.1177/20503121221098236
eng
2,022
null
null
2,022
5
19
[OBJECTIVES] Although neutropenic fever is one of the most well-known oncologic emergencies and the common causes of death, a few studies have been conducted in resource-limited countries, particularly in Ethiopia. This study aimed to assess the burden, risk factors, and management of neutropenic fever among solid canc...
Burden; Ethiopia; University of Gondar; guideline adherence; neutropenic fever; solid cancer; treatment
0.613
41
Medicine
Medicine
2,022
35,646,304
Perioperative glycemic status is linked to postoperative complications in non-intensive care unit patients with type-2 diabetes: a retrospective study.
Therapeutic advances in endocrinology and metabolism
Ther Adv Endocrinol Metab
13
null
10.1177/20420188221099349
eng
2,022
null
null
2,022
5
19
[BACKGROUND] Perioperative hyperglycemia is a risk factor for postoperative complications in the general population. However, it has not been clarified whether perioperative hyperglycemia increases postoperative complications in patients with type-2 diabetes mellitus (T2D). Therefore, we aimed to analyze the relationsh...
perioperative blood glucose management; postoperative complications
1.058
49
Endocrinology, Diabetes and Metabolism
Medicine
2,022
35,646,254
Perceived Barriers to Pediatric Clinical Trials Implementation: A Survey of Health Care Staff.
Kansas journal of medicine
Kans J Med
15
2
10.17161/kjm.vol15.15885
eng
2,022
null
null
2,022
5
17
[INTRODUCTION] Clinical trials are the gold standard for assessing the effectiveness and safety of treatments. The objective of this study was to assess provider opinions regarding implementing pediatric clinical trials in various practice settings across Kansas. [METHODS] The study was completed within the Sunflower P...
clinical trials; engagement; enrollment; pediatrics; providers
null
null
null
null
null
35,646,231
Telerehabilitation is Effective to Recover Functionality and Increase Skeletal Muscle Mass Index in COVID-19 Survivors.
International journal of telerehabilitation
Int J Telerehabil
13
2
10.5195/ijt.2021.6415
eng
2,021
null
null
2,021
12
16
[OBJECTIVE] The purpose of this study was to evaluate the effects of a telerehabilitation program for COVID-19 survivors on their functionality, aerobic capacity, upper-lower body strength and skeletal muscle mass index. [METHODS] Fifty patients (22 M); age 54.1±15.4 who became ill with COVID-19 during 2020 completed a...
Barthel index; COVID-19; Hand grip strength; Physical therapy; Skeletal muscle mass; Telerehabilitation
0.6
17
Rehabilitation; Computer Science Applications; Health Informatics; Health Information Management
Computer Science; Health Professions; Medicine
2,021
35,646,130
Operationally defining physical literacy in Chinese culture: Results of a meta-narrative synthesis and the Panel's recommendations.
Journal of exercise science and fitness
J Exerc Sci Fit
20
3
10.1016/j.jesf.2022.04.003
eng
2,022
7
null
2,022
5
5
[PURPOSE] The definition of physical literacy (PL) needs to be explored by researchers from educational, public health, and sports organisations in Chinese culture; an adequate definition and theoretical framework of PL can then be embraced within different contexts and according to cultural influences. [METHODS] This ...
Chinese culture; Meta-narrative synthesis; Physical literacy; Systematic review
0.71
35
Pharmaceutical Science; Pharmacology; Physical Therapy, Sports Therapy and Rehabilitation; Public Health, Environmental and Occupational Health; Sports Science
Health Professions; Medicine; Nursing; Pharmacology, Toxicology and Pharmaceutics
2,022
35,645,758
Safety and Feasibility of a Novel Exoskeleton for Locomotor Rehabilitation of Subjects With Spinal Cord Injury: A Prospective, Multi-Center, and Cross-Over Clinical Trial.
Frontiers in neurorobotics
Front Neurorobot
16
null
10.3389/fnbot.2022.848443
eng
2,022
null
null
2,022
5
12
[OBJECTIVE] To evaluate the safety, walking efficiency, physiological cost, don and doff time cost, and user satisfaction of Ai-robot. [DESIGN] Prospective, multi-center, and cross-over trial. [SUBJECTS] Paraplegic subjects (n = 40) with T6-L2 level spinal cord injury. [METHODS] Subjects who could walk independently us...
exoskeleton; orthosis; paraplegia; rehabilitation; spinal cord injury (SCI); walking aid
null
null
null
null
null
35,645,754
Advancing Prediction of Risk of Intraoperative Massive Blood Transfusion in Liver Transplantation With Machine Learning Models. A Multicenter Retrospective Study.
Frontiers in neuroinformatics
Front Neuroinform
16
null
10.3389/fninf.2022.893452
eng
2,022
null
null
2,022
5
13
[BACKGROUND] Liver transplantation surgery is often accompanied by massive blood loss and massive transfusion (MT), while MT can cause many serious complications related to high mortality. Therefore, there is an urgent need for a model that can predict the demand for MT to reduce the waste of blood resources and improv...
liver transplantation; machine learning; massive blood transfusion; prediction model; red cell transfusion
null
null
null
null
null
35,644,742
Establishing the Minimal Clinically Important Difference and Substantial Clinical Benefit for the Pain Visual Analog Scale in a Postoperative Hand Surgery Population.
The Journal of hand surgery
J Hand Surg Am
47
7
10.1016/j.jhsa.2022.03.009
eng
2,022
7
null
2,022
5
27
[PURPOSE] Although the pain visual analog scale (VAS-pain) is a ubiquitous patient-reported outcome instrument, it remains unclear how to interpret changes or differences in scores. Therefore, our purpose was to calculate the minimal clinically important difference (MCID) and substantial clinical benefit (SCB) for the ...
Minimal clinically important difference (MCID); patient-reported outcomes; substantial clinical benefit (SCB); visual analog pain (VAS-pain) score
1.093
142
Orthopedics and Sports Medicine; Surgery
Medicine
2,022
35,644,731
Comparison of outcomes between abdominal, minimally invasive and combined vaginal-laparoscopic hysterectomy in patients with stage IAI/IA2 cervical cancer: 4C (Canadian Cervical Cancer Collaborative) study.
Gynecologic oncology
Gynecol Oncol
166
2
10.1016/j.ygyno.2022.05.011
eng
2,022
8
null
2,022
5
27
[OBJECTIVE] Although minimally invasive hysterectomy (MIS-H) has been associated with worse survival compared to abdominal hysterectomy (AH) for cervical cancer, only 8% of patients in the LACC trial had microinvasive disease (Stage IA1/IA2). We sought to determine differences in outcome among patients undergoing MIS-H...
Cervical cancer; Minimally invasive surgery
1.674
192
Obstetrics and Gynecology; Oncology
Medicine
2,022
35,644,459
An Analysis of a National Administrative Dataset Demonstrating No Evidence of Increase in Elective Primary Total Hip Arthroplasty Dislocation Rates When Postoperative Hip Precautions are Not Used.
The Journal of arthroplasty
J Arthroplasty
37
12
10.1016/j.arth.2022.05.040
eng
2,022
12
null
2,022
5
26
[BACKGROUND] The purpose of this study is to determine whether there is a higher dislocation rate when postoperative hip precautions are not used for primary total hip arthroplasty (THA). [METHODS] A survey was conducted of the hip precautions used by orthopaedic departments in England performing elective primary THA. ...
arthroplasty; dislocation; hip replacement; physiotherapy; postoperative care; total hip arthroplasty
2.028
171
Orthopedics and Sports Medicine
Medicine
2,022
35,644,437
Uncovering the mechanism of Huanglian-Wuzhuyu herb pair in treating nonalcoholic steatohepatitis based on network pharmacology and experimental validation.
Journal of ethnopharmacology
J Ethnopharmacol
296
null
10.1016/j.jep.2022.115405
eng
2,022
10
5
2,022
5
27
[ETHNOPHARMACOLOGICAL RELEVANCE] The Huanglian-Wuzhuyu herb pair (HWHP) is a classic Chinese herbal formula consisting of the root of Coptis chinensis Franch and dried, nearly mature scented fruit of Tetradium ruticarpum (A.Juss.) T.G.Hartley. It is widely utilized to treat gastrointestinal and liver diseases such as d...
Experimental validation; Huanglian-wuzhuyu herb pair; NLRP3 inflammasome; Network pharmacology; Nonalcoholic steatohepatitis
0.833
243
Drug Discovery; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,022
35,644,221
Rationale and design of switch Swedeheart: A registry-based, stepped-wedge, cluster-randomized, open-label multicenter trial to compare prasugrel and ticagrelor for treatment of patients with acute coronary syndrome.
American heart journal
Am Heart J
251
null
10.1016/j.ahj.2022.05.017
eng
2,022
9
null
2,022
5
26
[BACKGROUND] European treatment guidelines recommend prasugrel over ticagrelor for treating patients with non-ST-elevation acute coronary syndrome (ACS), prompting several Swedish administrative regions to transition from ticagrelor to prasugrel as the preferred treatment for patients with ACS. We aim to systematically...
null
2.155
211
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,644,141
Application of a Machine Learning-Based Decision Support Tool to Improve an Injury Surveillance System Workflow.
Applied clinical informatics
Appl Clin Inform
13
3
10.1055/a-1863-7176
eng
2,022
5
null
2,022
5
29
[BACKGROUND] Emergency department (ED)-based injury surveillance systems across many countries face resourcing challenges related to manual validation and coding of data. [OBJECTIVE] This study describes the evaluation of a machine learning (ML)-based decision support tool (DST) to assist injury surveillance department...
null
0.974
47
Computer Science Applications; Health Informatics; Health Information Management
Computer Science; Health Professions; Medicine
2,022
35,644,135
Endoscopic Endonasal Resection of a Cavernous Malformation of the Third Ventricle: Case Report and Literature Review.
Journal of neurological surgery. Part A, Central European neurosurgery
J Neurol Surg A Cent Eur Neurosurg
85
2
10.1055/s-0041-1741070
eng
2,024
3
null
2,022
5
29
[BACKGROUND] Suprasellar and third ventricle cavernous malformations (CMs) are uncommon. Conventional approaches such as interhemispheric and translamina terminalis approaches are often used to resect these lesions. Here we demonstrate the use of the endoscopic endonasal approach for a third ventricle CM. [CASE DESCRIP...
null
null
null
null
null
null
35,644,004
MicroRNA-141-3p attenuates oxidative stress-induced hepatic ischemia reperfusion injury via Keap1/Nrf2 pathway.
Molecular biology reports
Mol Biol Rep
49
8
10.1007/s11033-022-07570-3
eng
2,022
8
null
2,022
5
29
[BACKGROUND] Hepatic ischemia reperfusion injury (IRI) is a major factor affecting the prognosis of liver transplantation through a series of severe cell death and inflammatory responses. However, the potential role of miR-141-3p in hepatic IRI is currently unknown. [METHODS] We collected the serum of liver transplanta...
Apoptosis; Hepatic ischemia reperfusion injury; Keap1/Nrf2/HO-1; MiR-141-3p; Reactive oxygen species
0.578
96
Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,643,908
Impact of an enhanced recovery after surgery protocol on short-term outcomes in elderly patients undergoing pancreaticoduodenectomy.
HPB : the official journal of the International Hepato Pancreato Biliary Association
HPB (Oxford)
24
10
10.1016/j.hpb.2022.05.002
eng
2,022
10
null
2,022
5
13
[BACKGROUND] To determine whether the short-term benefits associated with an enhanced recovery after surgery programme (ERAS) following pancreaticoduodenectomy (PD) vary with age. [METHODS] 830 consecutive patients who underwent PD between January 2009 and March 2019 were divided according to age: elderly (≥75 years) v...
null
1.081
98
Gastroenterology; Hepatology
Medicine
2,022
35,643,833
Impact of maternal dyslipidemia on infant neurodevelopment: The Japan Environment and Children's Study.
Brain & development
Brain Dev
44
8
10.1016/j.braindev.2022.05.002
eng
2,022
9
null
2,022
5
25
[BACKGROUND] Various genetic and environmental influences have been studied for developmental disorders; however, the precise cause remains unknown. This study assessed the impact of maternal serum total cholesterol (TC) level in early pregnancy on early childhood neurodevelopment. [METHODS] The fixed data of 31,797 si...
Ages and Stages Questionnaire; Developmental disorder; Infant; Maternal serum cholesterol level; Neurodevelopment
null
null
null
null
null
35,643,829
Revealing hidden experiences: Gendered microaggressions and surgical faculty burnout.
Surgery
Surgery
172
3
10.1016/j.surg.2022.04.032
eng
2,022
9
null
2,022
5
25
[BACKGROUND] Studies report higher burnout in women faculty surgeons compared to men. However, few studies have examined underlying mechanisms for these gendered differences. Gendered differences in microaggression experiences may explain part of the relationship between gender and burnout. We aimed to investigate the ...
null
null
null
null
null
null
35,643,817
How does systemic lupus erythematosus impact the peri-operative complication rates in primary hip arthroplasty? A national inpatient sample-based study.
Archives of orthopaedic and trauma surgery
Arch Orthop Trauma Surg
143
4
10.1007/s00402-022-04475-5
eng
2,023
4
null
2,022
5
28
[INTRODUCTION] With prolonged life expectancy, the number of patients with systemic lupus erythematosus (SLE) undergoing total hip arthroplasty (THA) has substantially increased over the past years. The post-operative outcome and complications in SLE are less clearly understood than other inflammatory diseases, due to ...
Complications; Periprosthetic joint infection; Systemic lupus erythematosus; Total knee arthroplasty
1.036
98
Medicine; Orthopedics and Sports Medicine; Surgery
Medicine
2,023
35,643,406
Anterior versus Posterior Ventricular Catheter Placement in Pediatric Patients: A Systematic Review and Meta-Analysis.
World neurosurgery
World Neurosurg
167
null
10.1016/j.wneu.2022.05.057
eng
2,022
11
null
2,022
5
25
[BACKGROUND] Ventriculoperitoneal shunt placement is the mainstay of treatment for hydrocephalus, but there are relatively high rates of malfunction. Shunt catheter entry can be performed anteriorly or posteriorly, with the body of evidence from randomized controlled trials and retrospective studies suggesting conflict...
Drainage; Hydrocephalus; Pediatric neurosurgery; Shunt failure; Shunt survival; Ventriculoperitoneal shunt
0.591
123
Neurology; Surgery
Medicine
2,022
35,643,359
Temporal modulation of H-reflex in young and older people: Acute effects during Achilles tendon vibration while standing.
Experimental gerontology
Exp Gerontol
165
null
10.1016/j.exger.2022.111844
eng
2,022
8
null
2,022
5
26
[PURPOSE] Examining how timely is sensory input processed and regulated after a perturbation while standing, is a key element to understand postural control, especially in people with balance deficits, such as older adults. In this study, we investigated the age-related temporal modulations in spinal excitability, by m...
Center of pressure; Perturbation; Postural control; Proprioception; Soleus; Spinal excitability
0.937
164
Biochemistry; Cell Biology; Endocrinology; Genetics; Molecular Biology; Aging
Biochemistry, Genetics and Molecular Biology
2,022
35,643,216
Novel multiple sclerosis agents-associated cardiotoxicity: A real-world pharmacovigilance study.
International journal of cardiology
Int J Cardiol
362
null
10.1016/j.ijcard.2022.05.052
eng
2,022
9
1
2,022
5
26
[BACKGROUND] Emerging novel therapeutics have been developed to hamper the progression of multiple sclerosis (MS). However, the adverse events related to these new agents remain largely unknown. Therefore, we sought to investigate the cardiovascular complications of these drugs. [METHODS] Utilizing data from the U.S. f...
Daclizumab; Fingolimod; Multiple sclerosis; Ocrelizumab; Ofatumumab; Siponimod
1.122
155
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,643,173
Computer-Aided Detection Improves Adenomas per Colonoscopy for Screening and Surveillance Colonoscopy: A Randomized Trial.
Gastroenterology
Gastroenterology
163
3
10.1053/j.gastro.2022.05.028
eng
2,022
9
null
2,022
5
25
[BACKGROUND AND AIMS] Colonoscopy for colorectal cancer screening is endoscopist dependent, and colonoscopy quality improvement programs aim to improve efficacy. This study evaluated the clinical benefit and safety of using a computer-aided detection (CADe) device in colonoscopy procedures. [METHODS] This randomized st...
Adenomas; Artificial Intelligence; Colonoscopy; Histology
7.645
482
Gastroenterology; Hepatology
Medicine
2,022
35,642,966
Infective endocarditis following invasive dental procedures: IDEA case-crossover study.
Health technology assessment (Winchester, England)
Health Technol Assess
26
28
10.3310/NEZW6709
eng
2,022
5
null
null
null
null
[BACKGROUND] Infective endocarditis is a heart infection with a first-year mortality rate of ≈ 30%. It has long been thought that infective endocarditis is causally associated with bloodstream seeding with oral bacteria in ≈ 40-45% of cases. This theorem led guideline committees to recommend that individuals at increas...
ANTIBIOTIC PROPHYLAXIS; DENTAL CARE; DENTAL SCALING; DENTISTRY; ENDOCARDITIS; INFECTIVE; ORAL STREPTOCOCCI; ROOT CANAL THERAPY; TOOTH EXTRACTION
null
null
null
null
null
35,642,624
Predictive Value of High Preoperative Serum Total Protein and Elevated Hematocrit in Patients with Non-Small-Cell Lung Cancer after Radical Resection.
Nutrition and cancer
Nutr Cancer
74
10
10.1080/01635581.2022.2079683
eng
2,022
null
null
2,022
6
1
[BACKGROUND] The relationship between the dynamic alterations of nutritional indexes before and after surgery, and the prognosis of non-small-cell lung cancer (NSCLC) after radical surgery are unclear. Methods: This study enrolled 100 NSCLC patients in stages I-III who received radical surgery. The preoperative and pos...
null
0.634
135
Medicine; Nutrition and Dietetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine; Nursing
2,022
35,642,525
Maternal Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccination During Pregnancy: Impact on Infant Anti-Pertussis Antibody Concentrations by Maternal Pertussis Priming Series.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Clin Infect Dis
76
3
10.1093/cid/ciac432
eng
2,023
2
8
null
null
null
[BACKGROUND] Acellular pertussis (aP) vaccines replaced whole-cell pertussis (wP) vaccines for the US childhood primary series in 1997. As women primed with aP vaccines enter childbearing age, protection of infants through tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccination during preg...
Tdap; infants; maternal immunization; pertussis; pregnancy
3.308
398
Infectious Diseases; Microbiology
Medicine
2,023
35,642,252
Mutation Screening of TFG in α-Synucleinopathy and Amyotrophic Lateral Sclerosis.
Movement disorders : official journal of the Movement Disorder Society
Mov Disord
37
8
10.1002/mds.29079
eng
2,022
8
null
2,022
5
31
[BACKGROUND] Recently, p.R383H in TFG was identified as the disease cause in a family with α-synucleinopathy and amyotrophic lateral sclerosis (ALS). However, no further replication has been conducted in larger cohorts. [OBJECTIVE] The aim was to explore the genetic role of TFG in α-synucleinopathy and ALS. [METHODS] W...
TFG; Parkinson's disease; rare variant
2.602
238
Neurology; Neurology
Medicine; Neuroscience
2,022
35,641,260
The Prognostic Relevance of Preoperative CEA and CA19-9 for Ampulla of Vater Carcinoma.
Anticancer research
Anticancer Res
42
6
10.21873/anticanres.15806
eng
2,022
6
null
null
null
null
[BACKGROUND/AIM] Increased serum levels of carcinoembryonic antigen (CEA) and carbohydrate antigen 199 (CA19-9) are established prognostic factors in ampulla of Vater carcinoma (AC). We determined the best cut-off values of preoperative CEA and CA19-9 and compared the prognostic power of preoperative CEA with that of p...
Ampulla of Vater carcinoma; carbohydrate antigen 19-9; carcinoembryonic antigen
null
null
null
null
null
35,641,246
Variation in Peritoneal Dialysis Time on Therapy by Country: Results from the Peritoneal Dialysis Outcomes and Practice Patterns Study.
Clinical journal of the American Society of Nephrology : CJASN
Clin J Am Soc Nephrol
17
6
10.2215/CJN.16341221
eng
2,022
6
null
null
null
null
[BACKGROUND AND OBJECTIVES] Quantifying contemporary peritoneal dialysis time on therapy is important for patients and providers. We describe time on peritoneal dialysis in the context of outcomes of hemodialysis transfer, death, and kidney transplantation on the basis of the multinational, observational Peritoneal Dia...
hemodialysis; kidney transplantation; peritoneal dialysis
2.293
197
Critical Care and Intensive Care Medicine; Epidemiology; Nephrology; Transplantation
Medicine
2,022
35,640,996
Real-Time Analysis of Dry-Side Nebulization With Heated Wire Humidification During Mechanical Ventilation.
Respiratory care
Respir Care
67
8
10.4187/respcare.09459
eng
2,022
8
null
2,022
5
31
[BACKGROUND] Recent observational studies of nebulizers placed on the wet side of the humidifier suggest that, after some time, considerable condensation can form, which triggers an occlusion alarm. In the current study, an inline breath-enhanced jet nebulizer was tested and compared in vitro with a vibrating mesh nebu...
aerosol delivery; continuous drug delivery; inhalation administration; mechanical ventilation
0.656
112
Critical Care and Intensive Care Medicine; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022
35,640,870
External validation of vancomycin population pharmacokinetic models in ten cohorts of infected Chinese patients.
Journal of global antimicrobial resistance
J Glob Antimicrob Resist
30
null
10.1016/j.jgar.2022.05.016
eng
2,022
9
null
2,022
5
28
[OBJECTIVES] Appropriate dosage of vancomycin is critical for safety and efficacy in treating infectious diseases. Various population pharmacokinetic (PPK) models have been established. To lay a foundation for the clinical application, it is important to perform external validation of the published model. The aim of th...
External validation; Predictive performance; Vancomycin
0.879
55
Immunology; Immunology and Allergy; Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,022
35,640,528
"From hell to healed" - A qualitative study on women's experience of recovery, relationships and sexuality after severe obstetric perineal injury.
Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives
Sex Reprod Healthc
33
null
10.1016/j.srhc.2022.100736
eng
2,022
9
null
2,022
5
21
[OBJECTIVE] Few studies have investigated women's experiences of daily life after childbirth complicated by obstetric anal sphincter injury (OASI). The aim of the present study was to explore experiences related to recovery, sexual function, relationships and coping strategies among women affected by OASI. [METHODS] In...
Experiences; Obstetric anal sphincter injury; Qualitative; Relations; Sexual function
null
null
null
null
null
35,640,351
Why is my world so dark? Effects of child physical and emotional abuse on child depression: The mediating role of self-compassion and negative automatic thoughts.
Child abuse & neglect
Child Abuse Negl
129
null
10.1016/j.chiabu.2022.105677
eng
2,022
7
null
2,022
5
26
[BACKGROUND] The adverse effects of childhood maltreatment on the mental health of individuals have received increasing attention. However, it is unclear whether the effects of invisible emotional abuse and visible physical abuse differ on child depression and the mediating processes under this relationship. [OBJECTIVE...
Child depression; Emotional abuse; Negative automatic thoughts; Physical abuse; Self-compassion
null
null
null
null
null
35,639,816
The effects of wearing a face mask and of subsequent moisturizer use on the characteristics of sensitive skin.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
Skin Res Technol
28
5
10.1111/srt.13173
eng
2,022
9
null
2,022
5
31
[BACKGROUND] COVID-19 is a serious respiratory disease, and wearing masks has become essential in daily life. Nevertheless, the number of people complaining of skin problems caused by wearing masks is increasing. Therefore, we investigated the characteristics of changes in sensitive skin caused by wearing a mask. [MATE...
COVID-19; mask; redness; skin hydration; skin moisture; transepidermal water loss
0.577
85
Dermatology; Medicine
Medicine
2,022
35,639,719
Combination of Houttuynia cordata polysaccharide and Lactiplantibacillus plantarum P101 alleviates acute liver injury by regulating gut microbiota in mice.
Journal of the science of food and agriculture
J Sci Food Agric
102
15
10.1002/jsfa.12046
eng
2,022
12
null
2,022
7
1
[BACKGROUND] Polysaccharides and probiotics can play an outstanding role in the treatment of liver disease by regulating gut microbiota. Recently, the combined therapeutic effect of probiotics and polysaccharides has attracted the attention of researchers. Houttuynia cordata polysaccharide (HCP) combined with Lactiplan...
Houttuynia cordata polysaccharide; Lactiplantibacillus plantarum; gut microbiota; inflammation; oxidative stress
null
null
null
null
null
35,639,602
Clinical Safety Experience of TAK-003 for Dengue Fever: A New Tetravalent Live Attenuated Vaccine Candidate.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Clin Infect Dis
76
3
10.1093/cid/ciac418
eng
2,023
2
8
null
null
null
[BACKGROUND] An unmet medical need remains for an effective dengue tetravalent vaccine that can be administered irrespective of previous dengue exposure. TAK-003, a dengue tetravalent vaccine, has demonstrated efficacy in an ongoing phase 3 trial in children and adolescents living in dengue-endemic areas, with an accep...
TAK-003; adverse events; clinical safety; dengue tetravalent vaccine; hospitalization
3.308
398
Infectious Diseases; Microbiology
Medicine
2,023
35,639,334
Single direct right axillary artery cannulation using a modified Seldinger technique in minimally invasive cardiac surgery.
General thoracic and cardiovascular surgery
Gen Thorac Cardiovasc Surg
70
11
10.1007/s11748-022-01832-4
eng
2,022
11
null
2,022
5
31
[OBJECTIVES] Single direct right axillary artery cannulation is uncommon in minimally invasive cardiac surgery; however, the risk of cerebral infarction due to retrograde perfusion using the femoral artery remains high in patients with thoracoabdominal aortic atheroma. In our institution, we perform right axillary arte...
Axillary artery; Cardiac surgical procedure; Cerebral infarction; Minimally invasive surgical procedure
0.481
50
Surgery; Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022
35,639,231
Occurrence of Eustrongylides sp. (Nematoda: Dioctophymatidae) in Fish Species Collected in the Peruvian Amazonia and Its Implications for Public Health.
Acta parasitologica
Acta Parasitol
67
3
10.1007/s11686-022-00574-w
eng
2,022
9
null
2,022
5
31
[PURPOSE] The present study aims to report the occurrence of Eustrongylides sp. in some neotropical fish species commercialized in the Peruvian Amazonia. [METHODS] Samples of young farmed Arapaima gigas were collected from a fish farmer; young Brachyplatystoma tigrinum were acquired from a fish exporter and samples of ...
Endoparasite; Eustrongylides sp.; Nematoda; Peruvian Amazonia; Zoonosis
0.478
43
Parasitology
Immunology and Microbiology
2,022
35,639,174
Efficacy and safety of romosozumab among Japanese postmenopausal women with osteoporosis and mild-to-moderate chronic kidney disease.
Journal of bone and mineral metabolism
J Bone Miner Metab
40
4
10.1007/s00774-022-01332-8
eng
2,022
7
null
2,022
5
31
[INTRODUCTION] This post hoc analysis of the placebo-controlled phase 3 FRAME study assessed the efficacy and safety of romosozumab in a subpopulation of Japanese postmenopausal women with osteoporosis and chronic kidney disease (CKD). [MATERIALS AND METHODS] Data were analyzed by baseline estimated glomerular filtrati...
Chronic kidney disease; Japanese patients; Osteoporosis; Romosozumab
0.748
88
Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine; Orthopedics and Sports Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,638,920
Factors Influencing Male Nursing Students' Adaptation to College Life in Korea.
The journal of nursing research : JNR
J Nurs Res
30
4
10.1097/jnr.0000000000000502
eng
2,022
8
1
2,022
8
1
[BACKGROUND] Male nursing students face challenges in the nursing profession because of its female-centered nature. In particular, most male students in South Korea must complete military service while in college. Although these kinds of situations may make it difficult for them to adapt to college life, the number of ...
null
null
null
null
null
null
35,638,905
Effect of COVID-19 on outpatient services in patients with aortovascular disease: a UK multicentre study.
Annals of the Royal College of Surgeons of England
Ann R Coll Surg Engl
105
S2
10.1308/rcsann.2022.0018
eng
2,023
8
null
2,022
5
31
[INTRODUCTION] The SARS-CoV-2 coronavirus disease 2019 (COVID-19) pandemic has disrupted healthcare services worldwide. Outpatient services have necessarily been restructured to accommodate COVID-19 patients and to maintain social distancing measures. The aim of our study was to investigate how the COVID-19 pandemic ha...
Aortopathy; Aortovascular; COVID-19; Outpatients
0.359
79
Medicine; Surgery
Medicine
2,023
35,638,700
Should compromised first permanent molar teeth in children be routinely removed? A health economics analysis.
Community dentistry and oral epidemiology
Community Dent Oral Epidemiol
51
5
10.1111/cdoe.12751
eng
2,023
10
null
2,022
5
31
[OBJECTIVE] To evaluate the cost-effectiveness of retaining one or more compromised first permanent molars (cFPMs) affected by dental caries or enamel hypomineralization, compared to timely extraction, in children aged 8 years. [METHODS] A Markov model was developed to simulate the lifetime of a cFPM. Two management st...
null
0.896
118
Dentistry; Public Health, Environmental and Occupational Health
Dentistry; Medicine
2,023
35,638,544
Impact of Stroke Severity on the Smoking Paradox in Patients Treated with Intravenous Thrombolysis.
Current neurovascular research
Curr Neurovasc Res
19
2
10.2174/1567202619666220530092614
eng
2,022
null
null
null
null
null
[OBJECTIVE] To our knowledge, no previous studies have investigated the impact of stroke severity on the smoking paradox after intravenous thrombolysis (IVT). We aimed to explore the contribution of stroke severity to the association between smoking and stroke prognosis after IVT. [METHODS] We enrolled consecutive pati...
NIHSS score; Stroke; outcome; smoking paradox; stroke severity; thrombolysis
null
null
null
null
null
35,638,392
Positive airway pressure therapy in heart failure patients comorbid with obstructive sleep apnea: Cardiovascular outcomes and nighttime-duration effect.
European journal of clinical investigation
Eur J Clin Invest
52
10
10.1111/eci.13821
eng
2,022
10
null
2,022
6
6
[BACKGROUND] Comorbidity of obstructive sleep apnea (OSA) and heart failure (HF) is becoming increasingly common. This is a global analysis of positive airway pressure (PAP) efficacy for the cardiovascular outcomes in those HF Patients with comorbid OSA. [METHODS] Related randomized controlled trials were included. Ana...
cardiovascular function; heart failure; obstructive sleep apnea; positive airway pressure
1.3
126
Biochemistry; Clinical Biochemistry; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,638,285
Differential Impact of Biologic Therapy on Heart Function Biomarkers in Rheumatoid Arthritis Patients: Observational Study on Etanercept, Adalimumab, and Tocilizumab.
Current pharmaceutical design
Curr Pharm Des
28
24
10.2174/1381612828666220527141532
eng
2,022
null
null
null
null
null
[BACKGROUND] Rheumatoid arthritis (RA) represents the most frequent form of inflammatory arthritis, affecting approximately 1% of the population worldwide. The introduction of novel therapeutic strategies targeting proinflammatory cytokines (TNF-α and interleukin-6) revolutionized the treatment of RA. This kind of trea...
H-FABP; Heart function; MR-proANP; NT-proBNP; biologics; galectin-3; rheumatoid arthritis
0.58
190
Drug Discovery; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,022
35,638,106
Influence of flow and susceptibility effects on spin dephasing in lung tissue.
Medical physics
Med Phys
49
9
10.1002/mp.15784
eng
2,022
9
null
2,022
6
17
[PURPOSE] Magnetic resonance imaging (MRI) of the lung can be used for diagnosis and monitoring of interstitial lung disease. Biophysical models of alveolar lung tissue are needed to understand the complex interplay of susceptibility, diffusion, and flow effects, and their influence on magnetic resonance (MR) spin deph...
diffusion-weighted imaging; magnetic resonance imaging; magnetic susceptibility; microstructural tissue model
1.072
218
Biophysics; Medicine; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,638,069
The necessity of routine screening for deep vein thrombosis before surgery.
Annals of medicine and surgery (2012)
Ann Med Surg (Lond)
77
null
10.1016/j.amsu.2022.103627
eng
2,022
5
null
2,022
4
14
[BACKGROUND] Pulmonary embolism (PE) from deep venous thrombosis (DVT) can be a fatal postoperative complication. Preventive measures for venous thromboembolism (VTE) was evaluated in this hospital. [MATERIALS AND METHODS] Preoperative DVT screening following surgery under general anesthesia in 2009-2016 was examined, ...
DVT; Fondaparinux; Surgical management; Thromboprophylaxis; VTE
null
null
null
null
null
35,638,019
Surgical research in Colombia part 1: Scientific and academic productivity of the Colombian research groups in surgery.
Annals of medicine and surgery (2012)
Ann Med Surg (Lond)
77
null
10.1016/j.amsu.2022.103667
eng
2,022
5
null
2,022
4
28
[INTRODUCTION] Global surgery has become the undisputed starting point for addressing a myriad of problems in surgery today. Therefore, it is necessary to constantly evaluate the scientific productivity in surgery, its behavior, validity and impact. In Latin America, specifically in Colombia, there are no studies that ...
Colombia; General surgery; Publishing; Research; Research group
null
null
null
null
null
35,637,772
Sleep Stage Classification Based on Multi-Centers: Comparison Between Different Ages, Mental Health Conditions and Acquisition Devices.
Nature and science of sleep
Nat Sci Sleep
14
null
10.2147/NSS.S355702
eng
2,022
null
null
2,022
5
24
[PURPOSE] To investigate the general sleep stage classification performance of deep learning networks, three datasets, across different age groups, mental health conditions, and acquisition devices, comprising adults (SHHS) and children without mental health conditions (CCSHS), and subjects with mental health condition...
deep learning network; electroencephalogram; sleep stage classification; time-frequency spectrum
0.875
55
Applied Psychology; Behavioral Neuroscience
Neuroscience; Psychology
2,022
35,637,653
Clinical and Microbiological Efficacy of Adjunctive Systemic Quinolones to Mechanical Therapy in Periodontitis: A Systematic Review of the Literature.
International journal of dentistry
Int J Dent
2022
null
10.1155/2022/4334269
eng
2,022
null
null
2,022
5
21
[OBJECTIVES] To assess the clinical and microbiological efficacy of systemic quinolones adjunctive to mechanical therapy in periodontitis patients. Materials and Methods. A systematic review of the scientific literature was carried out. The search scheme comprised the Scopus, PubMed/MEDLINE, SCIELO (Scientific Electron...
null
0.47
57
Dentistry
Dentistry
2,022
35,637,608
Patients' perspectives of fluid management: A multicentre comparative study of home and incentre haemodialysis.
Journal of renal care
J Ren Care
49
2
10.1111/jorc.12426
eng
2,023
6
null
2,022
5
30
[BACKGROUND] There is increasing worldwide interest in person-centred care in haemodialysis and home haemodialysis (HHD). Intradialytic fluid management is a vital component of haemodialysis, and often a shared decision, yet patients' perspectives and experience of related decisions are largely unexplored. [OBJECTIVES]...
haemodialyses; home; patient participation; renal dialysis; ultrafiltration
0.58
34
Advanced and Specialized Nursing; Nephrology
Medicine; Nursing
2,023
35,637,501
Regional estimates of noncommunicable diseases associated risk factors among adults in India: results from National Noncommunicable Disease Monitoring Survey.
BMC public health
BMC Public Health
22
1
10.1186/s12889-022-13466-5
eng
2,022
5
30
2,022
5
30
[BACKGROUND] This study describes regional differences and determinants on key noncommunicable disease (NCD) risk factors in adults from the National NCD Monitoring Survey (NNMS) across six geographic regions of India. [METHODS] The NNMS was a cross-sectional multistage cluster survey conducted in 2017-18, on a represe...
Epidemiology; India; Noncommunicable diseases; Regions; Risk factors
1.307
211
Public Health, Environmental and Occupational Health
Medicine
2,022
35,637,448
Maternal dietary methionine restriction alters the expression of energy metabolism genes in the duckling liver.
BMC genomics
BMC Genomics
23
1
10.1186/s12864-022-08634-1
eng
2,022
5
30
2,022
5
30
[BACKGROUND] In mammals, the nutritional status experienced during embryonic development shapes key metabolic pathways and influences the health and phenotype of the future individual, a phenomenon known as nutritional programming. In farmed birds as well, the quantity and quality of feed offered to the dam can impact ...
Differentially expressed genes; Duck; Methyl donor; Nutritional programming
1.107
208
Biotechnology; Genetics
Biochemistry, Genetics and Molecular Biology
2,022
35,637,354
The Impact of Post-Thyroidectomy Neck Stretching Exercises on Neck Discomfort, Pressure Symptoms, Voice and Quality of Life: A Randomized Controlled Trial.
World journal of surgery
World J Surg
46
9
10.1007/s00268-022-06610-0
eng
2,022
9
null
2,022
5
30
[BACKGROUND] Following surgery for benign nodular goiter, patients may experience neck and shoulder pain, neck pressure and tightness, choking sensation, altered voice function, and dysphagia leading to decreased short-term quality of life (QoL). This single-blinded randomized controlled trial investigated the effect o...
null
0.902
176
Surgery
Medicine
2,022
35,637,152
Retroactive application of the EPIS framework to promote future implementation success in community pharmacy clinical interventions.
Journal of the American Pharmacists Association : JAPhA
J Am Pharm Assoc (2003)
62
5
10.1016/j.japh.2022.05.005
eng
2,022
null
null
2,022
5
7
[BACKGROUND] The assessment of the implementation process of a clinical intervention in a community pharmacy setting can reveal useful insights for future implementation efforts. [OBJECTIVE] We aimed to examine the implementation of a community pharmacist-led prospective registry and practice tool (RxING, Epidemiology ...
null
0.455
75
Pharmacology; Pharmacy; Pharmacology
Health Professions; Nursing; Pharmacology, Toxicology and Pharmaceutics
2,022
35,637,051
Bullous pemphigoid and milia: prevalence and clinical laboratory findings in a Brazilian sample.
Anais brasileiros de dermatologia
An Bras Dermatol
97
4
10.1016/j.abd.2021.10.003
eng
2,022
null
null
2,022
5
27
[BACKGROUND] Bullous pemphigoid (BP) associated with milia lesions has been increasingly reported, but its prevalence has not been reported in a Brazilian BP population yet. [OBJECTIVES] To describe the occurrence and clinical-laboratorial findings of BP-milia association in a southeastern Brazilian sample. [METHODS] A...
230 kDa protein; HLA antigens; Hemidesmosomal plaque protein; Pemphigoid, bullous
0.449
66
Dermatology
Medicine
2,022
35,636,788
Do people with symptoms of an infectious illness follow advice to stay at home? Evidence from a series of cross-sectional surveys about presenteeism in the UK.
BMJ open
BMJ Open
12
5
10.1136/bmjopen-2021-060511
eng
2,022
5
30
2,022
5
30
[OBJECTIVES] To assess the percentage of people in the UK with cough, fever or loss of taste or smell who have not had a positive COVID-19 test result who had been to work, to shops, socialised or provided care to a vulnerable person in the 10 days after developing symptoms. To investigate whether these rates differed ...
COVID-19; infection control; public health
1.059
176
Medicine
Medicine
2,022
35,636,500
Career Research Performance Among Radiology Early Career Grant Recipients Compared With National Institutes of Health K Award Recipients.
Journal of the American College of Radiology : JACR
J Am Coll Radiol
19
9
10.1016/j.jacr.2022.04.003
eng
2,022
9
null
2,022
5
28
[OBJECTIVE] To compare academic and demographic metrics among recipients of three major early career radiology, interventional radiology, and radiation oncology grants to National Institutes of Health (NIH) K awardees at the time the grants were awarded and then over the course of their careers. [METHODS] Radiologists ...
Early career grants; NIH; radiation oncology; radiology; research productivity
1.016
85
Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,636,409
Alexithymia and Cutaneous Disease Morbidity: A Systematic Review.
Dermatology (Basel, Switzerland)
Dermatology
238
6
10.1159/000524736
eng
2,022
null
null
2,022
5
30
[BACKGROUND] Alexithymia is a psychological construct that describes one's difficulty in understanding and describing their own emotions as well as differentiating feelings from bodily signals of arousal. In the general population, alexithymia's prevalence is approximately 10%. Alexithymia may act as a triggering facto...
Alexithymia; Emotional deficit; Psychocutaneous medicine; Psychodermatology; Quality of life
0.989
110
Dermatology
Medicine
2,022
35,636,265
Effectiveness of acceptance and commitment therapy for improving quality of life and mood in individuals with multiple sclerosis: A systematic review and meta-analysis.
Multiple sclerosis and related disorders
Mult Scler Relat Disord
63
null
10.1016/j.msard.2022.103862
eng
2,022
7
null
2,022
5
10
[OBJECTIVE] To review the evidence for the effectiveness of Acceptance and Commitment Therapy (ACT) intervention on quality of life and mood, for individuals with Multiple Sclerosis (MS). [METHOD] A systematic search was conducted of PsycINFO, CINAHL, Embase, MEDLINE, Web of Science, Scopus and ContextualScience.org up...
Acceptance and commitment therapy; Multiple sclerosis
0.92
70
Medicine; Neurology; Neurology
Medicine; Neuroscience
2,022
35,636,176
Identification of active components in Andrographis paniculata targeting on CD81 in esophageal cancer in vitro and in vivo.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Phytomedicine
102
null
10.1016/j.phymed.2022.154183
eng
2,022
7
20
2,022
5
20
[BACKGROUND] Esophageal cancer (EC) is highly prevalent in Eastern Asia (including China) with high rates of mortality. The metastatic tendency in EC is associated with a poor prognosis. Our previous studies have demonstrated the suppressive effects of Andrographis paniculata water extract (APW) on metastatic esophagea...
Andrographis paniculata; Bisandrographolide; CD81; Esophageal cancer; Metastasis; Tetrasapanin
1.126
150
Complementary and Alternative Medicine; Drug Discovery; Pharmaceutical Science; Pharmacology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,636,099
Pediatric vestibular migraine: Diagnosis according to ICHD-3 criteria and the effectiveness of short-term CH prophylaxis.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
Eur J Paediatr Neurol
39
null
10.1016/j.ejpn.2022.05.002
eng
2,022
7
null
2,022
5
13
[OBJECTIVE] Vestibular migraine (VM) is a rare migraine variant with limited information about its treatment in children. This study, it was aimed to evaluate the diagnostic characteristics of VM in children and the effectiveness of cyproheptadine hydrochloride (CH) prophylaxis. [METHODS] Patients aged 6-18 years who w...
Children; Migraine; Vertigo; Vestibular migraine
0.885
79
Medicine; Pediatrics, Perinatology and Child Health; Neurology
Medicine
2,022
35,635,840
Nursing Workflow Change in a COVID-19 Inpatient Unit Following the Deployment of Inpatient Telehealth: Observational Study Using a Real-Time Locating System.
Journal of medical Internet research
J Med Internet Res
24
6
10.2196/36882
eng
2,022
6
17
2,022
6
17
[BACKGROUND] The COVID-19 pandemic prompted widespread implementation of telehealth, including in the inpatient setting, with the goals to reduce potential pathogen exposure events and personal protective equipment (PPE) utilization. Nursing workflow adaptations in these novel environments are of particular interest gi...
COVID-19; PPE; health care professional; health care staff; health risk; informatics; nurses; nursing; pandemic; pathogen exposure; patient outcomes; patient safety; real-time locating system; telehealth; telemedicine; virtual care
1.992
214
Health Informatics
Medicine
2,022
35,634,622
Vitamin B12 in Pregnancy and its Relationship with Maternal BMI and Gestational Diabetes Mellitus - A study from Pakistan.
Pakistan journal of medical sciences
Pak J Med Sci
38
4Part-II
10.12669/pjms.38.4.5120
eng
2,022
null
null
null
null
null
[OBJECTIVES] To determine the levels of vitamin B12 in pregnant women and to explore the relationship of vitamin B12 with maternal BMI and gestational diabetes mellitus. [METHODS] This cross-sectional study was conducted at Department of Physiology, UHS, Lahore from February 2019 to March 2020. Ninety pregnant women in...
BMI; Gestational diabetes mellitus; Maternal obesity; Vitamin B12
null
null
null
null
null
35,634,612
Magnitude and pattern of anxiety levels with gender wise predilection of coping strategies amid resident doctors of emergency department.
Pakistan journal of medical sciences
Pak J Med Sci
38
4Part-II
10.12669/pjms.38.4.5105
eng
2,022
null
null
null
null
null
[OBJECTIVES] To screen and assess the severity level of anxiety, its influencing factors along with the gender-wise predilection of coping strategies among resident doctors working in accident and emergency departments. [METHODS] A transverse study was conducted amongst 260 resident doctors of accident and emergency de...
Anxiety; GAD-7; coping strategies; doctors; emergency department; resident; teaching hospitals
null
null
null
null
null
35,634,414
Association of Dietary Protein Intake and Grip Strength Among Adults Aged 19+ Years: NHANES 2011-2014 Analysis.
Frontiers in nutrition
Front Nutr
9
null
10.3389/fnut.2022.873512
eng
2,022
null
null
2,022
5
13
[BACKGROUND] Research on the role of protein in the diet has evolved beyond a focus on quantity to include the impact of its quality and distribution across meal times in an effort to optimize dietary protein recommendations. [OBJECTIVE] To determine the association of dietary protein amount, type, and intake pattern w...
National Health and Nutrition Examination Survey; animal protein; essential amino acids; muscle strength; plant protein; protein distribution; protein quality; total protein
0.875
94
Food Science; Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Agricultural and Biological Sciences; Medicine; Nursing
2,022
35,633,910
Sirtuin1 attenuates acute liver failure by reducing reactive oxygen species via hypoxia inducible factor 1α.
World journal of gastroenterology
World J Gastroenterol
28
17
10.3748/wjg.v28.i17.1798
eng
2,022
5
7
null
null
null
[BACKGROUND] The occurrence and development of acute liver failure (ALF) is closely related to a series of inflammatory reactions, such as the production of reactive oxygen species (ROS). Hypoxia inducible factor 1α (HIF-1α) is a key factor that regulates oxygen homeostasis and redox, and the stability of HIF-1α is rel...
Acute liver failure; Deacetylation; Reactive oxygen species; Sirtuin1
null
null
null
null
null
35,633,750
Distal femur complex fractures in elderly patients treated with megaprosthesis: Results in a case series of 11 patients.
World journal of orthopedics
World J Orthop
13
5
10.5312/wjo.v13.i5.454
eng
2,022
5
18
2,022
5
18
[BACKGROUND] Surgical treatment of complex fractures of the distal femur in the elderly is controversial. Osteoporosis and pre-existent osteoarthritis are common comorbidities in the elderly which add to the need for early walking and rapid restoration of function and also pose significant obstacles to achievement of s...
Distal femur fracture; Elderly; Joint replacement; Knee; Megaprosthesis
0.533
64
Orthopedics and Sports Medicine
Medicine
2,022
35,633,604
Bringing disability experiences front stage: Research-based theatre as a teaching approach to promote inclusive health education.
Nurse education today
Nurse Educ Today
115
null
10.1016/j.nedt.2022.105408
eng
2,022
8
null
2,022
5
21
[BACKGROUND] Despite efforts to promote inclusion of people living with disabilities in health and human service education and professions, students and clinicians living with disabilities continue to face powerful barriers, arising most notably from the stigma and negative attitudes of their peers. Increased awareness...
Attitudinal change; Disability; Health and human service professions; Higher education; Research-based Theatre
0.946
109
Education; Nursing
Nursing; Social Sciences
2,022
35,633,401
Comparison of low power and high power holmium YAG laser settings in flexible ureteroscopy.
World journal of urology
World J Urol
40
7
10.1007/s00345-022-04040-0
eng
2,022
7
null
2,022
5
28
[PURPOSE] To compare the efficacy of conventional low power and high power holmium: yttrium aluminum-garnet (Ho: YAG) laser lithotripsy settings during retrograde intrarenal surgery (RIRS). METHODS: The prospective study was conducted in patients undergoing RIRS for renal stones less than 2 cm diameter. Pulsed Ho:YAG l...
Dusting; Ho:YAG laser; Lithotripsy; Renal stones
1.014
104
Urology
Medicine
2,022
35,633,382
Adjacent segments biomechanics following lumbar fusion surgery: a musculoskeletal finite element model study.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Eur Spine J
31
7
10.1007/s00586-022-07262-3
eng
2,022
7
null
2,022
5
28
[PURPOSE] This study exploits a novel musculoskeletal finite element (MS-FE) spine model to evaluate the post-fusion (L4-L5) alterations in adjacent segment kinetics. [METHODS] Unlike the existing MS models with idealized representation of spinal joints, this model predicts stress/strain distributions in all passive ti...
Adjacent segments; Kinematics; Lumbar fusion surgery; Musculoskeletal finite element model; Spine loads
0.942
173
Orthopedics and Sports Medicine; Surgery
Medicine
2,022
35,633,376
Imaging the fetal nonhuman primate brain with SV2A positron emission tomography (PET).
European journal of nuclear medicine and molecular imaging
Eur J Nucl Med Mol Imaging
49
11
10.1007/s00259-022-05825-6
eng
2,022
9
null
2,022
5
28
[PURPOSE] Exploring synaptic density changes during brain growth is crucial to understanding brain development. Previous studies in nonhuman primates report a rapid increase in synapse number between the late gestational period and the early neonatal period, such that synaptic density approaches adult levels by birth. ...
In utero; Nonhuman primate; Positron emission tomography; SV2A; Synaptogenesis
2.1
192
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,633,236
An Outbreak Investigation of Varicella Zoster among Male Military Personnel in a Military Training Centre.
JNMA; journal of the Nepal Medical Association
JNMA J Nepal Med Assoc
60
249
10.31729/jnma.7440
eng
2,022
5
5
2,022
5
5
[INTRODUCTION] Chickenpox is an acute, highly infectious disease. Outbreaks can occur in adults in closed institutional settings like hostels and barracks. This study aims to report varicella zoster outbreak among male military personnel in a military training centre. [METHODS] An outbreak investigation of chickenpox i...
null
null
null
null
null
null
35,633,031
Annual report of the committee on gynecologic oncology, the Japan Society of Obstetrics and Gynecology: Annual patient report for 2019 and annual treatment report for 2014.
The journal of obstetrics and gynaecology research
J Obstet Gynaecol Res
48
7
10.1111/jog.15284
eng
2,022
7
null
2,022
5
27
[AIM] To provide information including the trend of gynecological malignancies in Japan, we hereby present the Annual Patient Report for 2019 and the Annual Treatment Report for 2014, on the outcomes of patients who started treatment in 2014. [METHODS] The Japan Society of Obstetrics and Gynecology maintains an annual ...
Japan; annual report; cervical cancer; endometrial cancer; gynecologic cancer; ovarian; tubal and peritoneal cancer
0.487
68
Obstetrics and Gynecology; Medicine
Medicine
2,022
35,630,291
A Method to Determine the Efficacy of a Commercial Phage Preparation against Uropathogens in Urine and Artificial Urine Determined by Isothermal Microcalorimetry.
Microorganisms
Microorganisms
10
5
10.3390/microorganisms10050845
eng
2,022
4
20
2,022
4
20
[BACKGROUND] Urinary tract infections are commonly encountered and often treated with antibiotics. However, the inappropriate use of the latter has led to the appearance of resistant strains. In this context we investigate the use of calorimetry to rapidly determine if a phage cocktail can be used as alternative to ant...
E. coli; P. mirabilis; bacteriophages; isothermal microcalorimetry; phage cocktail
0.909
112
Microbiology; Microbiology; Virology
Immunology and Microbiology; Medicine
2,022
35,629,016
A Comprehensive Approach to Facial Reanimation: A Systematic Review.
Journal of clinical medicine
J Clin Med
11
10
10.3390/jcm11102890
eng
2,022
5
20
2,022
5
20
[PURPOSE] To create a systematic overview of the available reconstructive techniques, facial nerve grading scales, physical evaluation, the reversibility of paralysis, non-reconstructive procedures and medical therapy, physical therapy, the psychological aspect of facial paralysis, and the prevention of facial nerve in...
facial paralysis; facial reanimation; free flaps
0.935
132
Medicine
Medicine
2,022
35,628,812
Risk Assessment of CHD Using Retinal Images with Machine Learning Approaches for People with Cardiometabolic Disorders.
Journal of clinical medicine
J Clin Med
11
10
10.3390/jcm11102687
eng
2,022
5
10
2,022
5
10
[BACKGROUND] Coronary heart disease (CHD) is the leading cause of death worldwide, constituting a growing health and social burden. People with cardiometabolic disorders are more likely to develop CHD. Retinal image analysis is a novel and noninvasive method to assess microvascular function. We aim to investigate wheth...
cardiometabolic disorders; coronary heart disease; machine learning; retinal images
0.935
132
Medicine
Medicine
2,022
35,627,711
Planning a Collection of Virtual Patients to Train Clinical Reasoning: A Blueprint Representative of the European Population.
International journal of environmental research and public health
Int J Environ Res Public Health
19
10
10.3390/ijerph19106175
eng
2,022
5
19
2,022
5
19
[BACKGROUND] Virtual patients (VPs) are a suitable method for students to train their clinical reasoning abilities. We describe a process of developing a blueprint for a diverse and realistic VP collection (prior to VP creation) that facilitates deliberate practice of clinical reasoning and meets educational requiremen...
case-based learning; clinical reasoning; international collaboration; medical education; open educational resources; virtual patients
0.828
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,022
35,626,874
Identification of Hub Genes and Immune Infiltration in Pediatric Biliary Atresia by Comprehensive Bioinformatics Analysis.
Children (Basel, Switzerland)
Children (Basel)
9
5
10.3390/children9050697
eng
2,022
5
10
2,022
5
10
[BACKGROUND] Biliary atresia (BA) is the leading cause of pediatric liver failure and pediatric liver transplantation worldwide. Evidence suggests that the immune system plays a central role in the pathogenesis of BA. [METHODS] In this work, the novel immune-related genes between BA and normal samples were investigated...
WGCNA; biliary atresia; biomarkers; children; immune-related genes
0.504
56
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,624,490
Intermittent fasting reduces neuroinflammation in intracerebral hemorrhage through the Sirt3/Nrf2/HO-1 pathway.
Journal of neuroinflammation
J Neuroinflammation
19
1
10.1186/s12974-022-02474-2
eng
2,022
5
27
2,022
5
27
[BACKGROUND] Inflammation contributes to the poor prognosis of intracerebral hemorrhage (ICH). Intermittent fasting (IF) has been shown to be protective against inflammation in multiple pathogenic processes. In the present study, we aimed to investigated the beneficial effects of IF in attenuating neuroinflammation and...
Inflammation; Intermittent fasting; Intracerebral hemorrhage; Microglia; Sirt3
2.439
168
Cellular and Molecular Neuroscience; Immunology; Neurology; Neuroscience
Immunology and Microbiology; Neuroscience
2,022
35,624,453
Stability of enveloped and nonenveloped viruses in hydrolyzed gelatin liquid formulation.
Virology journal
Virol J
19
1
10.1186/s12985-022-01819-w
eng
2,022
5
27
2,022
5
27
[BACKGROUND] The thermal stability of viruses in gelatin liquid formulations for medical research and application is poorly understood and this study aimed to examine the thermal stability of 4 enveloped and nonenveloped DNA and RNA viruses in hydrolyzed gelatin liquid formulations. [METHODS] Bovine herpesvirus (BHV) w...
Formulation; Hydrolyzed gelatin; Stability; Temperature; Virus
1.092
104
Infectious Diseases; Virology
Immunology and Microbiology; Medicine
2,022
35,624,168
Association between fetal sex and pregnancy outcomes among women with twin pregnancies: a multicenter cross-sectional study.
Archives of gynecology and obstetrics
Arch Gynecol Obstet
307
5
10.1007/s00404-022-06623-z
eng
2,023
5
null
2,022
5
27
[PURPOSE] To examine the frequency and to what extent fetal sex is associated with pregnancy outcomes among twin pregnancies, stratified by chorionicity. [METHODS] This registry-based multicenter cross-sectional study was conducted using the Japan Society of Obstetrics and Gynecology perinatal database between 2007 and...
Birth weight; Fetal sex; Preeclampsia; Preterm birth; Twin pregnancy
0.782
90
Medicine; Obstetrics and Gynecology
Medicine
2,023
35,624,049
Dialysis in disaster: Using continuous renal replacement therapy for end-stage renal disease patients, a pilot proof of concept study.
The American journal of emergency medicine
Am J Emerg Med
58
null
10.1016/j.ajem.2022.05.007
eng
2,022
8
null
2,022
5
11
[INTRODUCTION] Each dialysis session uses approximately 150 to 200 L of water. The winter storm that swept southwest USA saw an unprecedented disruption of water supplies due to which intermittent hemodialysis could not be performed for end-stage renal disease (ESRD) patients. We present 4 cases when continuous renal r...
Continuous renal replacement therapy; Disaster; End-stage renal disease; dialysis
0.88
114
Emergency Medicine; Medicine
Medicine
2,022
35,623,957
Economic crisis in Greece: The invisible enemy of blood donation or not?
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
Transfus Apher Sci
61
6
10.1016/j.transci.2022.103467
eng
2,022
12
null
2,022
5
21
[INTRODUCTION] Volunteering presupposes having free time and refers to the provision of services without the motivation of material reward, for the benefit of society. In this study, we aimed to provide insight into the impact of economic crisis on blood donors and their motivation to donate blood during that period. [...
Blood donation; Financial crisis; Quality of life
0.49
66
Hematology
Medicine
2,022
35,623,454
Neutralizing Anti-Granulocyte Macrophage-Colony Stimulating Factor Autoantibodies Recognize Post-Translational Glycosylations on Granulocyte Macrophage-Colony Stimulating Factor Years Before Diagnosis and Predict Complicated Crohn's Disease.
Gastroenterology
Gastroenterology
163
3
10.1053/j.gastro.2022.05.029
eng
2,022
9
null
2,022
5
24
[BACKGROUND AND AIMS] Anti-granulocyte macrophage-colony stimulating factor autoantibodies (aGMAbs) are detected in patients with ileal Crohn's disease (CD). Their induction and mode of action during or before disease are not well understood. We aimed to investigate the underlying mechanisms associated with aGMAb induc...
Autoantibodies; GM-CSF; Innate Lymphoid Cells; Macrophages
7.645
482
Gastroenterology; Hepatology
Medicine
2,022
35,623,115
Anti-inflammation and gingival wound healing activities of Cannabis sativa L. subsp. sativa (hemp) extract and cannabidiol: An in vitro study.
Archives of oral biology
Arch Oral Biol
140
null
10.1016/j.archoralbio.2022.105464
eng
2,022
8
null
2,022
5
19
[OBJECTIVE] To evaluate the anti-inflammatory and gingival wound healing activities of Cannabis sativa L. subsp. sativa (hemp) extract and cannabidiol (CBD). [DESIGN] The cellular bioactivities of hemp extract and CBD were determined the inhibition of TNF-α and IL-1β in LPS-induced murine macrophage (RAW 264.7) cells b...
Cannabidiol; Cannabis sativa L.; Hemp; Wound healing
0.545
109
Dentistry; Medicine; Otorhinolaryngology; Cell Biology
Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine
2,022
35,623,104
Labor Force Participation and Hearing Loss Among Adults in the United States: Evidence From the National Health and Nutrition Examination Survey.
American journal of audiology
Am J Audiol
31
3
10.1044/2022_AJA-21-00266
eng
2,022
9
null
2,022
5
27
[PURPOSE] The purpose of this article was to study the association between hearing loss (HL) and labor force participation in the National Health and Nutrition Examination Survey (NHANES). [METHOD] This cross-sectional study used data from the 1999-2000, 2001-2002, 2003-2004, 2011-2012, and 2015-2016 cycles of the NHAN...
null
0.677
57
Speech and Hearing
Health Professions
2,022
35,623,020
How Is Quality of mHealth Interventions for Cancer Survivors Defined and Described? An Umbrella Review.
JCO clinical cancer informatics
JCO Clin Cancer Inform
6
null
10.1200/CCI.21.00203
eng
2,022
5
null
null
null
null
[PURPOSE] Although there are commonly accepted criteria of what defines quality of health care including cancer care, less is known about what defines quality of mHealth interventions in health care. The aim of this review was to identify how quality of mHealth interventions for cancer survivors is described and measur...
null
1.602
41
Cancer Research; Health Informatics; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,623,016
Toward Equitable Access to Tertiary Cancer Care in Rwanda: A Geospatial Analysis.
JCO global oncology
JCO Glob Oncol
8
null
10.1200/GO.21.00395
eng
2,022
5
null
null
null
null
[PURPOSE] Geographic access to care is an important measure of health equity. In this study, we describe geographic access to cancer care centers (CCCs) in Rwanda with the current facilities providing care and examine how access could change with expanded care infrastructure. [METHODS] Health facilities included are pu...
null
null
null
null
null
null
35,622,817
Trend and determinants of quality of family planning counseling in Ethiopia: Evidence from repeated PMA cross-sectional surveys, (2014-2019).
PloS one
PLoS One
17
5
10.1371/journal.pone.0267944
eng
2,022
null
null
2,022
5
27
[INTRODUCTION] The modern contraceptive prevalence rate (mCPR) among married women has increased by nearly five-fold in Ethiopia from 8.1% in 2000 to 37% in 2019. Despite this increase, receipt of high quality contraceptive counselling, as measured by the percentage of contraceptive users who were told about other meth...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
35,622,185
Cost-effectiveness of the MitraClip device in German heart failure patients with secondary mitral regurgitation.
The European journal of health economics : HEPAC : health economics in prevention and care
Eur J Health Econ
24
3
10.1007/s10198-022-01476-4
eng
2,023
4
null
2,022
5
27
[AIM] To evaluate the cost-effectiveness of the MitraClip device (MitraClip) in addition to optimal medical therapy (OMT) in patients with heart failure and secondary mitral regurgitation in Germany. [METHODS AND RESULTS] A model-based economic evaluation was performed to estimate the incremental cost per quality-adjus...
Cost-effectiveness; Germany; Heart failure; MitraClip; Secondary mitral regurgitation; Transcatheter-valve repair
1.08
71
Economics, Econometrics and Finance; Health Policy
Economics, Econometrics and Finance; Medicine
2,023