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35,612,502
Post-COVID-19 airway stenosis treated by tracheal resection and anastomosis: a bicentric experience.
Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale
Acta Otorhinolaryngol Ital
42
2
10.14639/0392-100X-N1952
eng
2,022
4
null
null
null
null
[OBJECTIVE] The COVID-19 pandemic was an extraordinary challenge for the global healthcare system not only for the number of patients affected by pulmonary disease, but also for the incidence of long-term sequalae. In this regard, laryngo-tracheal stenosis (LTS) represents one of the most common complications of invasi...
COVID-19; airway stenosis; tracheal intubation; tracheal resection; tracheostomy
0.56
58
Otorhinolaryngology
Medicine
2,022
35,611,882
Rural and urban differences in the implementation of Virtual Integrated Patient-Aligned Care Teams.
The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association
J Rural Health
39
1
10.1111/jrh.12676
eng
2,023
1
null
2,022
5
25
[PURPOSE] Workforce shortages contribute to geographic disparities in accessing primary care services. An innovative, clinic-to-clinic videoconferencing telehealth program in the Veterans Health Administration (VHA) called the Virtual Integrated Patient-Aligned Care Teams (V-IMPACT) was designed to increase veterans' a...
interdisciplinary team-based care; primary care; rural health; telemedicine
1.512
74
Public Health, Environmental and Occupational Health
Medicine
2,023
35,611,820
Quantitative Evaluation of Binocular Visual Perception in Patients With Strabismus: An Observational Study.
Journal of pediatric ophthalmology and strabismus
J Pediatr Ophthalmol Strabismus
60
2
10.3928/01913913-20220324-03
eng
2,023
null
null
2,022
5
25
[PURPOSE] To quantitatively evaluate and compare binocular visual perception between normal individuals and patients with different types of strabismus using a binocular phase combination paradigm. [METHODS] A total of 117 participants were included in the study and were divided into the normal control group, exophoria...
null
0.563
55
Medicine; Ophthalmology; Pediatrics, Perinatology and Child Health
Medicine
2,023
35,611,787
Mechanistic Involvement of Inflammation in Bortezomib-induced Peripheral Neuropathy.
Combinatorial chemistry high throughput screening
Comb Chem High Throughput Screen
25
10
10.2174/1386207325666220524144147
eng
2,022
null
null
null
null
null
[AIM] The aim of the study was to establish the role of inflammation in bortezomibinduced peripheral neuropathy (BIPN). [BACKGROUND] Peripheral neuropathy is the dose-limiting toxicity of bortezomib that can lead to discontinuation of the treatment. There are multiple mechanisms involved in the disposition of BIPN. How...
Bortezomib; Schwann cells; inflammatory mediators; myeloma; peripheral neuropathy; tumor necrosis factor-alpha
null
null
null
null
null
35,611,632
Bleeding patterns of women with heavy menstrual bleeding or dysmenorrhoea using the levonorgestrel-releasing intrauterine system: results from a real-world observational study in Japan (J-MIRAI).
The European journal of contraception reproductive health care : the official journal of the European Society of Contraception
Eur J Contracept Reprod Health Care
27
4
10.1080/13625187.2022.2067329
eng
2,022
8
null
2,022
5
25
[PURPOSE] To collect real-world safety and clinical outcome data on the levonorgestrel-releasing intrauterine system (LNG-IUS) for functional/organic heavy menstrual bleeding (HMB) and dysmenorrhoea in Japanese women (J-MIRAI). [MATERIALS AND METHODS] In this prospective, multicentre, single-cohort, open-label, post-au...
Dysmenorrhoea; heavy menstrual bleeding; levonorgestrel-releasing intrauterine system; menorrhagia multi-attribute scale; menstrual blood loss; pictorial blood loss assessment chart
null
null
null
null
null
35,611,368
Circular RNA circLRCH3 Inhibits Proliferation, Migration, and Invasion of Colorectal Cancer Cells Through miRNA-223/LPP Axis.
OncoTargets and therapy
Onco Targets Ther
15
null
10.2147/OTT.S366605
eng
2,022
null
null
2,022
5
18
[PURPOSE] Colorectal cancer (CRC) is one of the most common carcinomas worldwide with a high mortality rate. Numerous studies suggest that circular RNA (circRNA) plays a crucial role in the progression of various carcinomas, including CRC. The present work focused on exploring the role and underlying molecular mechanis...
GEO; LPP; TCGA; circLRCH3; colorectal cancer; miR-223
0.836
94
Oncology; Pharmacology
Medicine
2,022
35,611,290
Late Presentation of Palmar Dislocation of the Fifth Metacarpal Bone: Review of the Literature, Treatment Algorithm, and Case Report.
Journal of orthopaedic case reports
J Orthop Case Rep
12
1
10.13107/jocr.2022.v12.i01.2630
eng
2,022
1
null
null
null
null
[INTRODUCTION] Isolated palmar carpometacarpal dislocation of the small finger is infrequent, this injury often goes unnoticed in the evaluation at the emergency room, for which physical evaluation and X-ray findings can avoid missing this diagnosis. We describe a case report and propose a treatment algorithm for isola...
Dislocation; fifth metacarpal bone; late presentation; treatment
null
null
null
null
null
35,610,756
Evaluating specimen pooling for Neisseria gonorrhoeae, Chlamydia trachomatis, and Mycoplasma genitalium screening in asymptomatic men who have sex with men.
International journal of STD AIDS
Int J STD AIDS
33
8
10.1177/09564624221100098
eng
2,022
7
null
2,022
5
24
[BACKGROUND] Screening for Neisseria gonorrhoeae and Chlamydia trachomatis is recommended for individuals at high-risk for sexually transmitted infections (STIs), while the role of Mycoplasma genitalium screening is still unclear. We evaluated whether specimen pooling is an effective alternative for sexually transmitte...
Sexually transmitted infections; chlamydia; gonorrhea; mycoplasma; screening; specimen pooling
null
null
null
null
null
35,610,636
Patient satisfaction with health care at a tertiary hospital in Northern Malawi: results from a triangulated cross-sectional study.
BMC health services research
BMC Health Serv Res
22
1
10.1186/s12913-022-08087-y
eng
2,022
5
24
2,022
5
24
[BACKGROUND] In 2016 the Malawi government embarked on several interrelated health sector reforms aimed at improving the quality of health services at all levels of care and attain Universal Health Coverage by 2030. Patient satisfaction with services is an important proxy measure of quality. We assessed patient satisfa...
Client satisfaction; Health care; Patient satisfaction; Quality of care
0.964
157
Health Policy
Medicine
2,022
35,610,622
Ubiquitin-like modifier 1 ligating enzyme 1 relieves cisplatin-induced premature ovarian failure by reducing endoplasmic reticulum stress in granulosa cells.
Reproductive biology and endocrinology : RBE
Reprod Biol Endocrinol
20
1
10.1186/s12958-022-00956-9
eng
2,022
5
24
2,022
5
24
[BACKGROUND] Ubiquitin-like modifier 1 ligating enzyme 1 (UFL1), the ligase of the UFMylation system, has recently been reported to be involved in apoptosis and endoplasmic reticulum stress (ER stress) in a variety of diseases. Premature ovarian failure (POF) is a gynecological disease that severely reduces the fertili...
Apoptosis; Cisplatin; ER stress; GCs; POF; UFL1
1.059
118
Obstetrics and Gynecology; Reproductive Medicine; Developmental Biology; Endocrinology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,610,151
Clinical research on the use of bordered foam dressings in the treatment of complex wounds: A systematic review of reported outcomes and applied measurement instruments.
Journal of tissue viability
J Tissue Viability
31
3
10.1016/j.jtv.2022.05.005
eng
2,022
8
null
2,022
5
19
[OBJECTIVE] The aim of this review article was to identify reported outcomes and measurement instruments used in clinical research on bordered foam dressings in the treatment of complex wounds. [METHODS] MEDLINE (PubMed interface), Cumulative Index to Nursing and Allied Health Literature (CINAHL), EMBASE, and The Cochr...
Bordered foam dressings; Complex wounds; Core outcome set; Systematic review; Treatment
0.572
45
Dermatology; Pathology and Forensic Medicine
Medicine
2,022
35,609,876
Fasting Glucose Variability and the Risk of Dementia in Individuals with Diabetes: A Nationwide Cohort Study.
Diabetes metabolism journal
Diabetes Metab J
46
6
10.4093/dmj.2021.0346
eng
2,022
11
null
2,022
5
24
[BACKGROUND] We investigated whether fasting glucose (FG) variability could predict the risk of dementia. [METHODS] This cohort study analyzed data from Koreans with diabetes after at least three health examinations by the Korean National Health Insurance Corporation between 2005 and 2010, which included at least one e...
Alzheimer disease; Dementia; Dementia, vascular; Diabetes mellitus; Glucose
null
null
null
null
null
35,609,860
Tuberculosis incidence in patients with chronic kidney disease: a systematic review and meta-analysis.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Int J Infect Dis
122
null
10.1016/j.ijid.2022.05.046
eng
2,022
9
null
2,022
5
21
[OBJECTIVE] The aim of this study was to estimate global TB incidence in patients with CKD. [METHODS] The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method was followed to perform the study. Electronic and gray literature sources were investigated for studies published between 2000 and ...
Chronic Kidney Disease; Incidence; Tuberculosis
2.006
140
Infectious Diseases; Medicine; Microbiology
Medicine
2,022
35,609,764
Parental embodied mentalizing: Associations with maternal depression, anxiety, verbal mentalizing, and maternal styles of interaction.
Journal of affective disorders
J Affect Disord
311
null
10.1016/j.jad.2022.05.105
eng
2,022
8
15
2,022
5
21
[BACKGROUND] Maternal depression and anxiety in the perinatal period affect the quality of maternal sensitivity and mentalizing abilities. Few studies analyzed implicit mentalizing in relation to maternal distress. The aims of the study were: to examine the relation between nonverbal mentalizing - parental embodied men...
Maternal anxiety; Maternal depression; Maternal styles of interaction; Mind-mindedness; Parental embodied mentalizing; Reflective functioning
1.988
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
35,609,162
Identifying Suicidal Ideation and Attempt From Clinical Notes Within a Large Integrated Health Care System.
The Permanente journal
Perm J
26
1
10.7812/TPP/21.102
eng
2,022
4
5
2,022
4
5
[PURPOSE] The purpose of this study was to develop a natural language processing algorithm to identify suicidal ideation/attempt from free-text clinical notes. [METHODS] Clinical notes containing prespecified keywords related to suicidal ideation/attempts from 2010 to 2018 were extracted from our organization's electro...
null
0.364
50
Medicine
Medicine
2,022
35,608,702
Prenatal paternal depression, anxiety, and somatic symptom burden in different risk samples: an explorative study.
Archives of gynecology and obstetrics
Arch Gynecol Obstet
307
4
10.1007/s00404-022-06612-2
eng
2,023
4
null
2,022
5
24
[PURPOSE] Growing evidence implies that transition to parenthood triggers symptoms of mental burden not only in women but likewise in men, especially in high-risk pregnancies. This is the first study that examined and compared the prevalence rates of depression, anxiety, and somatic symptom burden of expectant fathers ...
Anxiety; Hospitalization; Prenatal paternal depression; Risk pregnancy; Somatic symptom burden
0.782
90
Medicine; Obstetrics and Gynecology
Medicine
2,023
35,608,292
Incidence and risk factors for parastomal hernia with a permanent colostomy.
Journal of surgical oncology
J Surg Oncol
126
3
10.1002/jso.26919
eng
2,022
9
null
2,022
5
24
[AIM] This study aims to explore the incidence and risk factors for permanent colostomy complicated with a parastomal hernia (PSH) after rectal cancer resection. [METHODS] This was a retrospective study of gastrointestinal surgery performed from January 2013 to December 2017 in patients with colorectal cancer treated a...
colostomy; complication; incidence; parastomal hernia; risk factors
0.836
136
Surgery; Medicine; Oncology
Medicine
2,022
35,607,984
Local Instrumental Variable Methods to Address Confounding and Heterogeneity when Using Electronic Health Records: An Application to Emergency Surgery.
Medical decision making : an international journal of the Society for Medical Decision Making
Med Decis Making
42
8
10.1177/0272989X221100799
eng
2,022
11
null
2,022
5
24
[BACKGROUND] Electronic health records (EHRs) offer opportunities for comparative effectiveness research to inform decision making. However, to provide useful evidence, these studies must address confounding and treatment effect heterogeneity according to unmeasured prognostic factors. Local instrumental variable (LIV)...
cost-effectiveness analysis; emergency surgery; heterogeneous treatment effects; instrumental variable; personalized medicine
1.262
124
Health Policy
Medicine
2,022
35,607,498
Affective health and countermeasures in long-duration space exploration.
Heliyon
Heliyon
8
5
10.1016/j.heliyon.2022.e09414
eng
2,022
5
null
2,022
5
13
[BACKGROUND] Space research is shifting attention toward interplanetary expeditions. Therefore, whether long-duration spaceflight may influence affective health is becoming an urgent issue. [METHOD] To this end, we undertook a literature search and reviewed several behavioral simulation studies on Earth that focused on...
Affective health; Emotion; Mood; Resilience; Space mission; Stress
0.609
115
Multidisciplinary
Multidisciplinary
2,022
35,607,432
A prospective matched case-control study on the genomic epidemiology of colistin-resistant Enterobacterales from Dutch patients.
Communications medicine
Commun Med (Lond)
2
null
10.1038/s43856-022-00115-6
eng
2,022
null
null
2,022
5
20
[BACKGROUND] Colistin is a last-resort treatment option for infections with multidrug-resistant Gram-negative bacteria. However, colistin resistance is increasing. [METHODS] A six-month prospective matched case-control study was performed in which 22 Dutch laboratories with 32 associated hospitals participated. Laborat...
Antimicrobial resistance; Epidemiology; Infectious-disease epidemiology
null
28
Assessment and Diagnosis; Epidemiology; Internal Medicine; Medicine; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,022
35,606,880
Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region.
Genome medicine
Genome Med
14
1
10.1186/s13073-022-01058-2
eng
2,022
5
24
2,022
5
24
[BACKGROUND] Genome-wide association studies of asthma have revealed robust associations with variation across the human leukocyte antigen (HLA) complex with independent associations in the HLA class I and class II regions for both childhood-onset asthma (COA) and adult-onset asthma (AOA). However, the specific variant...
Asthma; Fine-mapping; HLA
4.851
133
Genetics; Genetics; Molecular Biology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,606,842
Patients' lived experiences of breathlessness prior to prehospital care - A phenomenological study.
Nursing open
Nurs Open
9
4
10.1002/nop2.1247
eng
2,022
7
null
2,022
5
23
[AIMS AND OBJECTIVES] The study aimed to describe how breathlessness is experienced by patients prior to prehospital care. [DESIGN] A qualitative phenomenological design. [METHODS] Lifeworld interviews were conducted with 14 participants. The analysis was carried out within the descriptive phenomenological framework. [...
ambulance; breathlessness; caring science; lived experiences; phenomenology; prehospital care; qualitative research
0.636
44
Nursing
Nursing
2,022
35,606,765
Patients' cancer care perceptions conceptualized through the Cancer Experience Measurement Framework.
BMC health services research
BMC Health Serv Res
22
1
10.1186/s12913-022-07946-y
eng
2,022
5
23
2,022
5
23
[BACKGROUND] Research on patients' perceptions of cancer care often documents sub-optimal experiences. Cancer care quality issues include restricted service access, lack of care coordination, gaps in follow-up and "generic" rather than person-centered care. Recent reports underscore that proactively and periodically se...
Cancer care; Content analysis; Patient experience measurement framework; Patient experiences; Patient satisfaction; Person-centered care
0.964
157
Health Policy
Medicine
2,022
35,606,759
Advances in clinical applications of kisspeptin-GnRH pathway in female reproduction.
Reproductive biology and endocrinology : RBE
Reprod Biol Endocrinol
20
1
10.1186/s12958-022-00953-y
eng
2,022
5
23
2,022
5
23
[BACKGROUND] Kisspeptin is the leading upstream regulator of pulsatile and surge Gonadotrophin-Releasing Hormone secretion (GnRH) in the hypothalamus, which acts as the key governor of the hypothalamic-pituitary-ovary axis. [MAIN TEXT] Exogenous kisspeptin or its receptor agonist can stimulate GnRH release and subseque...
Female reproduction; Hypothalamic-pituitary-ovarian axis; Hypothalamus; KISS1R; Kisspeptin
1.059
118
Obstetrics and Gynecology; Reproductive Medicine; Developmental Biology; Endocrinology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,606,757
Effectiveness of end-stage renal disease communication skills training for healthcare personnel: a single-center, single-blind, randomized study.
BMC medical education
BMC Med Educ
22
1
10.1186/s12909-022-03458-9
eng
2,022
5
23
2,022
5
23
[BACKGROUND] Given that the consequences of treatment decisions for end-stage renal disease (ESRD) patients are long-term and significant, good communication skills are indispensable for health care personnel (HCP) working in nephrology. However, HCP have busy schedules that make participation in face-to-face courses d...
Communication; Continuing medical education; Nephrology; Online education; Shared decision-making; Truth disclosure
0.914
107
Education; Medicine
Medicine; Social Sciences
2,022
35,606,617
Recovery and Resilience in the Canal Community: Economic Impacts and Solutions During the COVID-19 Pandemic.
Journal of racial and ethnic health disparities
J Racial Ethn Health Disparities
10
3
10.1007/s40615-022-01310-w
eng
2,023
6
null
2,022
5
23
[BACKGROUND] Public health pandemics, such as COVID-19, not only impact the physical health and wellbeing of communities but also often have far-reaching effects on their social, psychological, environmental, and economic welfare. The coronavirus pandemic has highlighted the significant inequities experienced among tho...
COVID-19 testing; Community health; Debt; Employment; Housing; Racial inequities; Social determinants of health; Social services
1.55
56
Anthropology; Health Policy; Health; Public Health, Environmental and Occupational Health; Sociology and Political Science
Medicine; Social Sciences
2,023
35,605,876
Urinary tetracycline antibiotics exposure during pregnancy and maternal thyroid hormone parameters: A repeated measures study.
The Science of the total environment
Sci Total Environ
838
Pt 2
10.1016/j.scitotenv.2022.156146
eng
2,022
9
10
2,022
5
21
[BACKGROUND] Studies on potential maternal thyrotoxicity related to tetracycline antibiotics exposure during pregnancy are lacking. Based on a large prospective cohort study, this study aimed to examine the associations between tetracycline antibiotics exposure in maternal urine and maternal thyroid hormone parameters....
Antibiotics; Biomonitoring; Exposure; Pregnancy; Thyroid hormones; Urine biomarkers
1.946
399
Environmental Chemistry; Environmental Engineering; Pollution; Waste Management and Disposal
Environmental Science
2,022
35,605,139
Gabapentin initiation in the inpatient setting: A characterization of prescribing.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Am J Health Syst Pharm
79
Suppl 3
10.1093/ajhp/zxac140
eng
2,022
8
19
null
null
null
[PURPOSE] Gabapentin is a widely prescribed analgesic with increased popularity over recent years. Previous studies have characterized use of gabapentin in the outpatient setting, but minimal data exist for its initiation in the inpatient setting. The objective of this study was to characterize the prescribing patterns...
gabapentin; hospitalization; inappropriate prescribing; inpatients
0.464
110
Pharmacy; Health Policy; Medicine; Pharmacology
Health Professions; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,604,879
Is COVID-19 vaccine inequality undermining the recovery from the COVID-19 pandemic?
Journal of global health
J Glob Health
12
null
10.7189/jogh.12.05020
eng
2,022
5
23
2,022
5
23
[BACKGROUND] The devastating health and economic impact of the COVID-19 pandemic led to a global response in the development of effective vaccines to fight the disease in an extraordinarily short time. Both the development and the production of these vaccines opened a path of hope, but the inequality in vaccine distrib...
null
1.286
71
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,022
35,604,721
Applications of the Guarded-Needle External Drainage Technique in Vitreoretinal Surgery.
Retina (Philadelphia, Pa.)
Retina
43
12
10.1097/IAE.0000000000003483
eng
2,023
12
1
null
null
null
[PURPOSE] To describe the surgical technique using the guarded-needle external drainage for a wide variety of applications in vitreoretinal surgery. [METHODS] A step-by-step procedure and a surgical video using the guarded-needle external drainage technique are presented. In addition, a series of representative cases w...
null
1.214
149
Medicine; Ophthalmology
Medicine
2,023
35,604,699
The clinical value of conventional ultrasound combined with contrast-enhanced ultrasound in the evaluation of BI-RADS 4 lesions detected by magnetic resonance imaging.
The British journal of radiology
Br J Radiol
95
1136
10.1259/bjr.20220025
eng
2,022
8
1
2,022
5
30
[OBJECTIVE] To determine the value of conventional ultrasound combined with contrast-enhanced ultrasound (CEUS) in Breast Imaging Reporting and Data System (BI-RADS) Category 4 lesions as detected by MRI. [METHODS] A total of 176 breast lesions from 171 patients were detected by MRI and categorised as BI-RADS 4. All pa...
null
0.757
128
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,604,576
Epicardial catheter ablation of idiopathic ventricular arrhythmias originating from uncommon epicardial sites.
Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing
J Interv Card Electrophysiol
66
1
10.1007/s10840-022-01149-5
eng
2,023
1
null
2,022
5
23
[PURPOSE] Idiopathic epicardial ventricular arrhythmias (VAs) are clustered in the areas of the summit and crux. This study was to report a group of idiopathic epicardial VAs remote from the summit and crux areas. [METHODS] In total, 9 patients (6 males, mean age 32 ± 13 years) were enrolled. The locations were identif...
Ablation; ECG; Epicardium; Ventricular arrhythmias
0.767
66
Cardiology and Cardiovascular Medicine; Medicine; Physiology
Medicine
2,023
35,604,252
Could direct transdeltoid approach to severely displaced proximal humerus fracture be advantageous for a better reduction?
Acta bio-medica : Atenei Parmensis
Acta Biomed
92
S3
10.23750/abm.v92iS3.12583
eng
2,022
3
10
2,022
3
10
[BACKGROUND] Surgical treatment of proximal humeral fractures (PHF) is a challenge for orthopaedic surgeons. Despite the wide application of open reduction and internal fixation with locking plates, the optimal surgical approach of PHF is still debated. This study aims to evaluate the radiological outcomes, defined as ...
null
null
null
null
null
null
35,603,843
Association of Personal Characteristics and Effectiveness of Immunotherapy in Late-Stage Non-Small Cell Lung Cancer: A Systematic Review.
JNCI cancer spectrum
JNCI Cancer Spectr
6
2
10.1093/jncics/pkac015
eng
2,022
3
2
null
null
null
[BACKGROUND] Although immunotherapy can increase survival in non-small cell lung cancer (NSCLC), response rates are low. It is unclear which characteristics contribute to variability in immunotherapy efficacy and survival. Research is needed to identify reasons for heterogeneity in response rates to better tailor treat...
null
2.377
39
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,603,531
Sex differences in efficacy of pharmacological therapies in heart failure with reduced ejection fraction: a meta-analysis.
ESC heart failure
ESC Heart Fail
9
4
10.1002/ehf2.13974
eng
2,022
8
null
2,022
5
23
[AIMS] Recent studies have suggested potential sex differences in treatment response to pharmacological therapies in heart failure (HF). We performed a systematic review and meta-analysis of studies comparing treatment effects between men and women with HF and reduced ejection fraction (HFrEF) using established guideli...
Guideline-directed medical therapy; Heart failure with reduced ejection fraction; Pharmacology; Sex differences
0.899
57
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,603,480
Hepatic ultrastructural features distinguish paediatric Wilson disease from NAFLD and autoimmune hepatitis.
Liver international : official journal of the International Association for the Study of the Liver
Liver Int
42
11
10.1111/liv.15319
eng
2,022
11
null
2,022
6
6
[BACKGROUND AND AIMS] Wilson disease (WD) has diverse presentations that frequently mimic other liver diseases. Distinguishing WD from non-alcoholic fatty liver disease (NAFLD) and autoimmune hepatitis (AIH), can be difficult and has critical implications for medical management. This study aimed to examine the utility ...
ATP7B; copper; mitochondria; oxidative stress; steatosis
1.929
145
Hepatology
Medicine
2,022
35,603,265
A rapid antibody screening haemagglutination test for predicting immunity to SARS-CoV-2 variants of concern.
Communications medicine
Commun Med (Lond)
2
null
10.1038/s43856-022-00091-x
eng
2,022
null
null
2,022
4
5
[BACKGROUND] Evaluation of susceptibility to emerging SARS-CoV-2 variants of concern (VOC) requires rapid screening tests for neutralising antibodies which provide protection. [METHODS] Firstly, we developed a receptor-binding domain-specific haemagglutination test (HAT) to Wuhan and VOC (alpha, beta, gamma and delta) ...
Predictive markers; RNA vaccines; Viral infection
null
28
Assessment and Diagnosis; Epidemiology; Internal Medicine; Medicine; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,022
35,603,128
An investigation into human papillomavirus (HPV) vaccination for patients undergoing surgery for high-grade cervical or vulvar dysplasia.
Gynecologic oncology reports
Gynecol Oncol Rep
41
null
10.1016/j.gore.2022.101001
eng
2,022
6
null
2,022
5
15
[INTRODUCTION] Eligibility for the human papillomavirus (HPV) vaccine now includes adults 27 through 45 years. It has not been reported how providers are addressing HPV vaccination in patients with existing preinvasive disease. Our objectives were to determine the rates at which vaccination is offered to and received b...
Adjuvant HPV vaccination; Cervical dysplasia; HPV vaccination; Human papillomavirus; Vulvar dysplasia
0.406
28
Obstetrics and Gynecology; Oncology
Medicine
2,022
35,602,853
Secondary Traumatic Stress and Moral Injury in Maternity Care Providers: A Narrative and Exploratory Review.
Frontiers in global women's health
Front Glob Womens Health
3
null
10.3389/fgwh.2022.835811
eng
2,022
null
null
2,022
5
4
[INTRODUCTION] A significant percentage of maternity providers have experienced secondary traumatic stress following a traumatic birth. Previous studies identified it as an issue, but this literature review is 5-9 years old. In addition, the construct of moral injury has significantly increased our understanding of sec...
labor and delivery; maternity; midwives; moral injury; obstetricians; secondary trauma
null
22
Medicine
Medicine
2,022
35,602,177
The impact of parental monitoring on cyberbullying victimization in the COVID-19 era.
Social science quarterly
Soc Sci Q
103
2
10.1111/ssqu.13134
eng
2,022
3
null
2,022
3
22
[OBJECTIVE] The purpose of the current research was to examine the predictors of cyberbullying victimization among South Korean students during a period in which the coronavirus disease was spreading worldwide. We assessed whether parental guardianship protected against victimization when most people worked from home a...
South Korea; cyberbullying; parental guardianship; routine activities theory
null
null
null
null
null
35,601,422
Case Report: Juvenile Myelomonocytic Leukemia Underlying Ornithine Transcarbamylase Deficiency Safely Treated Using Hematopoietic Stem Cell Transplantation.
Frontiers in pediatrics
Front Pediatr
10
null
10.3389/fped.2022.898531
eng
2,022
null
null
2,022
5
6
[BACKGROUND] Juvenile myelomonocytic leukemia (JMML), which is predominantly found in infants, is a clonal abnormality of pluripotent hematopoietic stem cells and presents with the symptoms of both myeloproliferative tumors and myelodysplastic syndromes. Estimates have shown that ~20 cases of JMML occur annually in Jap...
chemotherapy; hematopoietic stem cell transplantation; hyperammonemia; juvenile myelomonocytic leukemia; ornithine transcarbamylase deficiency; urea cycle disorder
0.798
83
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,601,347
Evaluation of intaglio surface trueness, wear, and fracture resistance of zirconia crown under simulated mastication: a comparative analysis between subtractive and additive manufacturing.
The journal of advanced prosthodontics
J Adv Prosthodont
14
2
10.4047/jap.2022.14.2.122
eng
2,022
4
null
2,022
4
27
[PURPOSE] This in-vitro analysis aimed to compare the intaglio trueness, the antagonist's wear volume loss, and fracture load of various single-unit zirconia prostheses fabricated by different manufacturing techniques. [MATERIALS AND METHODS] Zirconia crowns were prepared into four different groups (n = 14 per group) a...
Additive manufacturing; Antagonist wear; Fracture resistance; Intaglio surface trueness; Simulated mastication; Subtractive manufacturing; Zirconia
0.784
50
Dentistry; Oral Surgery
Dentistry
2,022
35,600,612
Neurophysiological Effects of the Anterior Cingulate Cortex on the Exacerbation of Crohn's Disease: A Combined fMRI-MRS Study.
Frontiers in neuroscience
Front Neurosci
16
null
10.3389/fnins.2022.840149
eng
2,022
null
null
2,022
5
6
[BACKGROUND] Crohn's disease (CD) is characterized by repetitive phases of remission and exacerbation, the quality of life of patients with CD is strongly influenced by disease activity, as patients in the active phase experience significantly worse symptoms. To investigate the underlying mechanism of how the course of...
anterior cingulate cortex; brain-gut axis; functional magnetic resonance imaging; magnetic resonance spectroscopy
1.161
170
Neuroscience
Neuroscience
2,022
35,600,449
Perceived academic satisfaction level, psychological stress and academic risk among Indian students amidst COVID-19 pandemic.
Heliyon
Heliyon
8
5
10.1016/j.heliyon.2022.e09440
eng
2,022
5
null
2,022
5
14
[BACKGROUND] The Covid-19 pandemic has a significant impact on education and mental health outcomes. This study attempts to analyze the factors associated with academic satisfaction level, psychological stress/anxiety, and future academic risk among Indian students of higher education in the wake of the Covid-19 pandem...
Academic risk; Academic satisfaction; Higher education; Mental health; Psychological stress
0.609
115
Multidisciplinary
Multidisciplinary
2,022
35,599,943
Antisecretory and antioxidative effects of the antidepressants fluvoxamine and mirtazapine on water immersion stress and pyloric ligation-induced gastric ulcer in rats.
International journal of health sciences
Int J Health Sci (Qassim)
16
3
null
eng
2,022
null
null
null
null
null
[OBJECTIVES] Although there are numerous drugs available for the treatment of gastric ulcers (GU), these drugs are not always effective. Antidepressant medications have been used for a variety of non-psychiatric indications, including antiulcer activity in various ulcer models. The purpose of this study was to compare ...
Fluvoxamine; gastric ulcer; mirtazapine; oxidative stress; pyloric ligation
null
null
null
null
null
35,599,602
Antibiotic utilization in emergency dental care in Stockholm 2016: a cross sectional study.
Acta odontologica Scandinavica
Acta Odontol Scand
80
7
10.1080/00016357.2022.2049864
eng
2,022
10
null
2,022
5
21
[OBJECTIVES] To investigate systemic antibiotics utilization in emergency dental care and to determine the most common treatment measures performed during emergency visits in public versus private emergency care in Sweden. [MATERIAL AND METHODS] Two questionnaires were answered by dentists at one large public and one l...
Acute odontogenic infection; antibiotic prescription; emergency dental clinic
0.506
81
Dentistry; Medicine
Dentistry; Medicine
2,022
35,599,072
Adverse impact of postoperative intra-abdominal infectious complications on cancer recurrence-related survival after curative gastric cancer surgery.
American journal of surgery
Am J Surg
224
3
10.1016/j.amjsurg.2022.05.009
eng
2,022
9
null
2,022
5
16
[BACKGROUND] This study aimed to evaluate the impact of postoperative intra-abdominal infectious complications (PICs) on survival after surgery for gastric cancer. [METHODS] A total of 152 patients who underwent curative gastrectomy for gastric cancer were included. The effect of clinicopathological features and PICs o...
Gastric cancer; Intraoperative bleeding; Postoperative complication
0.85
173
Surgery; Medicine
Medicine
2,022
35,598,676
Pleural tuberculosis: experiences from two centers in Brazil.
Jornal de pediatria
J Pediatr (Rio J)
98
6
10.1016/j.jped.2022.03.006
eng
2,022
null
null
2,022
5
20
[OBJECTIVE] This study aimed to describe the clinical and laboratory findings of patients diagnosed with pleural tuberculosis at two hospitals in southern Brazil. [METHODS] Patients aged 18 years were evaluated retrospectively. The patients' medical and epidemiological history, tuberculin skin test results, radiologic...
Adenosine deaminase; Mycobacterium infection; Pleural diseases
0.713
66
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,598,579
Palmitoylethanolamide-based nutraceutical Calmux® in preventive treatment of migraine.
Clinical neurology and neurosurgery
Clin Neurol Neurosurg
218
null
10.1016/j.clineuro.2022.107282
eng
2,022
7
null
2,022
5
8
[BACKGROUND] The aim of this study was to determine the efficacy and tolerability of treatment with a Palmitoylethanolamide (PEA)-based nutraceutical in patients with episodic migraine. [METHODS] A pilot, prospective, open-label experimental study was designed in which patients with episodic migraine with and without a...
Migraine; PEA; Palmitoylethanolamide; Preventive treatment
0.538
89
Medicine; Surgery; Neurology
Medicine
2,022
35,598,359
Olaparib tolerability and common adverse-event management in patients with metastatic castration-resistant prostate cancer: Further analyses from the PROfound study.
European journal of cancer (Oxford, England : 1990)
Eur J Cancer
170
null
10.1016/j.ejca.2022.04.016
eng
2,022
7
null
2,022
5
19
[BACKGROUND] Based on PROfound, olaparib is approved for patients with metastatic castration-resistant prostate cancer following disease progression on at least enzalutamide or abiraterone and who carry relevant alterations in DNA repair genes. To facilitate continued olaparib treatment as long as the patient derives b...
Adverse-event management; Metastatic castration-resistant prostate cancer; Olaparib; PROfound; Safety
2.898
256
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,598,293
Economic and clinical burden associated with respiratory viral infections after allogeneic hematopoietic cell transplant in the United States.
Transplant infectious disease : an official journal of the Transplantation Society
Transpl Infect Dis
24
4
10.1111/tid.13866
eng
2,022
8
null
2,022
6
1
[BACKGROUND] Allogeneic hematopoietic cell transplant (allo-HCT) recipients are at increased risk for respiratory viral infections (RVIs), which invoke substantial morbidity and mortality. Limited effective antiviral options and drug resistance often hamper successful RVI treatment, creating additional burden for patie...
allogeneic HCT; clinical burden; health care burden; respiratory viral infection
0.632
79
Infectious Diseases; Transplantation
Medicine
2,022
35,598,249
Alantolactone Inhibits Melanoma Cell Culture Viability and Migration and Promotes Apoptosis by Inhibiting Wnt/β-Catenin Signaling.
Anti-cancer agents in medicinal chemistry
Anticancer Agents Med Chem
23
1
10.2174/1871520622666220519100054
eng
2,023
null
null
null
null
null
[BACKGROUND] Melanoma is a highly invasive and metastatic malignant tumor originating from melanocytes and is associated with a poor prognosis. Surgical resection and chemotherapy are currently the main therapeutic options for malignant melanoma; however, their efficacy is poor, highlighting the need for the developmen...
Chinese medicinal herb; Melanoma; alantolactone; anti-tumor; apoptosis; cell culture
null
null
null
null
null
35,598,203
Foot drop as the initial symptom caused by thoracic disc herniation.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Eur Spine J
31
7
10.1007/s00586-022-07254-3
eng
2,022
7
null
2,022
5
22
[BACKGROUND] Foot drop is a syndrome resulting from weakness or paralysis of the tibialis anterior muscle. Some patients with thoracic disc herniation seek medical help complain of foot drop as the initial symptom. The study investigated the clinical characteristics of these patients and clarified the clinical efficacy...
Decompression; Disc herniation; Foot drop; Thoracic vertebra
0.942
173
Orthopedics and Sports Medicine; Surgery
Medicine
2,022
35,597,846
Systematic analysis of volumetric ultrasound parameters for markerless 4D motion tracking.
International journal of computer assisted radiology and surgery
Int J Comput Assist Radiol Surg
17
11
10.1007/s11548-022-02665-5
eng
2,022
11
null
2,022
5
21
[OBJECTIVES] Motion compensation is an interesting approach to improve treatments of moving structures. For example, target motion can substantially affect dose delivery in radiation therapy, where methods to detect and mitigate the motion are widely used. Recent advances in fast, volumetric ultrasound have rekindled t...
Image guidance; Motion estimation; Radiotherapy; Tracking; Ultrasound
0.831
71
Computer Graphics and Computer-Aided Design; Computer Vision and Pattern Recognition; Radiology, Nuclear Medicine and Imaging; Surgery; Biomedical Engineering; Computer Science Applications; Health Informatics; Medicine
Computer Science; Engineering; Medicine
2,022
35,597,491
Comparison of a pulsatile and a continuous flow left ventricular assist device in high-risk PCI.
International journal of cardiology
Int J Cardiol
360
null
10.1016/j.ijcard.2022.05.038
eng
2,022
8
1
2,022
5
18
[BACKGROUND] Mechanical circulatory support devices are able to generate additional cardiac output or maintain sufficient circulation during high-risk PCI. We prospectively compared the hemodynamic and clinical performance of the new iVAC2L® device with the Impella 2.5® device during high-risk PCI. [MATERIALS AND METHO...
High-risk PCI; Left ventricular assist device; Mechanical circulatory support
1.122
155
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,596,696
Effect of gestational age at laser therapy on perinatal outcome in monochorionic diamniotic pregnancies affected by twin-to-twin transfusion syndrome.
BJOG : an international journal of obstetrics and gynaecology
BJOG
129
12
10.1111/1471-0528.17228
eng
2,022
11
null
2,022
6
20
[OBJECTIVE] To evaluate the effect of gestational age at laser therapy for twin-to-twin transfusion syndrome (TTTS) on perinatal outcome. [DESIGN AND SETTINGS] Single retrospective observational cohort. [POPULATION] All consecutive pregnancies affected by TTTS and referred to our department between January 2013 and Aug...
fetal surgery; fetoscopic laser therapy; monochorionic; prognosis; twin-to-twin transfusion syndrome; twins
2.203
195
Obstetrics and Gynecology
Medicine
2,022
35,596,192
Genomic features of Chinese small cell lung cancer.
BMC medical genomics
BMC Med Genomics
15
1
10.1186/s12920-022-01255-3
eng
2,022
5
20
2,022
5
20
[BACKGROUND] Small cell lung cancer (SCLC) is an aggressive disease with poor survival. Although molecular and clinical characteristics have been established for SCLC in western patients, limited investigation has been performed for Chinese SCLC patients. [OBJECTIVE] In this study, we investigated the genomic features ...
Actionable alterations; DNA damage repair; Germline; Small cell lung cancer; TMB
0.892
99
Genetics; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,596,129
Correlation between perioperative parecoxib use and postoperative acute kidney injury in patients undergoing radical mastectomy: a retrospective cohort analysis.
BMC anesthesiology
BMC Anesthesiol
22
1
10.1186/s12871-022-01688-4
eng
2,022
5
20
2,022
5
20
[BACKGROUND] Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely prescribed drugs worldwide. However, the effect of NSAIDS on postoperative renal function is still unclear. Few studies have assessed the effects of parecoxib on renal function. Our aim is to investigate a correlation between parecoxi...
Acute kidney injury; Mastectomy; Parecoxib
0.609
58
Anesthesiology and Pain Medicine
Medicine
2,022
35,596,051
Evaluation of potential of miR-8073 and miR-642 as diagnostic markers in pancreatic cancer.
Molecular biology reports
Mol Biol Rep
49
7
10.1007/s11033-022-07476-0
eng
2,022
7
null
2,022
5
20
[BACKGROUND] Pancreatic cancer is a cancer with an insidious course. Since disease is often diagnosed at advanced stages, clinical outcome is impaired. Thus identification of biomarkers for this malignancy has importance in enhancement of patients' survival. [METHODS AND RESULTS] In the current study, we assessed expre...
Biomarker; Pancreatic cancer; miR-642; miR-8073
0.578
96
Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,595,636
Hunting-Based Food Donation Programs: Program Characteristics Across the US.
Journal of nutrition education and behavior
J Nutr Educ Behav
54
7
10.1016/j.jneb.2022.03.003
eng
2,022
7
null
2,022
5
17
[OBJECTIVE] Hunting-based food donation (HBFD) programs are unique food assistance programs because they provide under-resourced food bank participants with a quality protein source. This study aimed to summarize the characteristics of US HBFD programs and discuss the potential barriers and considerations to use or acc...
food assistance program; food bank; food donation; food security
0.695
99
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
35,595,450
Whole exome sequencing identifies a novel FRAS1 mutation and aids in vitro fertilization with preimplantation genetic diagnosis in Fraser syndrome.
Taiwanese journal of obstetrics gynecology
Taiwan J Obstet Gynecol
61
3
10.1016/j.tjog.2022.03.022
eng
2,022
5
null
null
null
null
[OBJECTIVE] To demonstrate the picture of a woman who had three times of pregnancies but fetuses were complicated with Fraser syndrome, a rare genetic disorder with multiple congenital anomalies. [CASE REPORT] Here are three complicated pregnancies with predominant features of severe oligohydramnios and other variable ...
Fraser syndrome/genetics; Intrafamilial variance; Oligohydramnios; Prenatal diagnosis; Whole exome sequencing
null
null
null
null
null
35,595,172
Micelle-Incorporated Liquid Chromatography in the Light of Green Chemistry: An Application for the Quality Control Analysis of Anti-Platelet Fixed-Dose Combinations.
Journal of AOAC International
J AOAC Int
105
5
10.1093/jaoacint/qsac046
eng
2,022
9
6
null
null
null
[BACKGROUND] Oral anti-platelet agents are the cornerstone of the treatment of multiple cardiovascular diseases and in the long-term prevention of their recurrence. [OBJECTIVE] In the present work, we report a method based on micellar liquid chromatography coupled with ultraviolet detection (MLC/UV), for the simultaneo...
null
0.358
106
Agronomy and Crop Science; Analytical Chemistry; Environmental Chemistry; Food Science; Pharmacology
Agricultural and Biological Sciences; Chemistry; Environmental Science; Pharmacology, Toxicology and Pharmaceutics
2,022
35,595,004
Comorbidities in childhood-onset and adult-onset asthma.
Annals of allergy, asthma immunology : official publication of the American College of Allergy, Asthma, Immunology
Ann Allergy Asthma Immunol
129
3
10.1016/j.anai.2022.05.005
eng
2,022
9
null
2,022
5
18
[BACKGROUND] Age of asthma onset has emerged as an important determinant of asthma phenotypes; however, the comorbidities that predominate in either childhood- or adult-onset asthma are not known. [OBJECTIVE] To identify comorbidities associated with adult-onset asthma vs childhood-onset asthma and with age of asthma d...
null
null
null
null
null
null
35,594,789
De novo sensorineural hearing loss sequelae of narrow, duplicated internal auditory canal: Case series and literature review.
International journal of surgery case reports
Int J Surg Case Rep
95
null
10.1016/j.ijscr.2022.107109
eng
2,022
6
null
2,022
4
20
[INTRODUCTION] A narrow duplicated internal auditory canal (IAC) is an extremely rare anomaly, likely associated with congenital sensorineural hearing loss due to aplasia/hypoplasia of the vestibulocochlear nerve or the cochlear branch alone. We aimed to review our experience with IAC duplication, describe its clinical...
Congenital; Duplication; Hearing loss; Internal auditory canal; Sensorineural
0.193
31
Surgery
Medicine
2,022
35,594,630
Reference values of low body mass index, mid-upper arm circumference, and calf circumference in cancer patients: A nationwide multicenter observational study.
Nutrition (Burbank, Los Angeles County, Calif.)
Nutrition
99-100
null
10.1016/j.nut.2022.111688
eng
2,022
null
null
2,022
4
11
[OBJECTIVE] Anthropometric measurements including body mass index (BMI), mid-upper arm circumference (MUAC), and calf circumference (CC) are simple and convenient indicators of nutritional status and muscle mass. However, most of their reference values come from studies based on healthy Western populations. The optimal...
Body mass index; Calf circumference; Cancer; Mid-upper arm circumference; Reference value
0.966
168
Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Medicine; Nursing
2,022
35,594,613
Treatments after second progression in metastatic colorectal cancer: A pooled analysis of the TRIBE and TRIBE2 studies.
European journal of cancer (Oxford, England : 1990)
Eur J Cancer
170
null
10.1016/j.ejca.2022.04.019
eng
2,022
7
null
2,022
5
17
[BACKGROUND] The availability of new drugs in the chemo-refractory setting opened the way to the concepts of treatment sequencing in mCRC. However, the impact of later line options in the therapeutic route of metastatic colorectal cancer (mCRC) patients and the attrition rate across subsequent lines of therapy are not ...
Attrition rate; Chemo-refractory disease; Metastatic colorectal cancer; RAS/BRAF genotyping
2.898
256
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,594,562
Treatment With Reduced-Dose Trimethoprim-Sulfamethoxazole Is Effective in Mild to Moderate Pneumocystis jirovecii Pneumonia in Patients With Hematologic Malignancies.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Clin Infect Dis
76
3
10.1093/cid/ciac386
eng
2,023
2
8
null
null
null
[BACKGROUND] Recent studies have reported that reduced-dose trimethoprim-sulfamethoxazole (TMP-SMX) may be effective in the treatment of Pneumocystis jirovecii pneumonia (PJP), but data are lacking for patients with hematologic malignancies. [METHODS] This retrospective study included all adult hematologic patients wit...
Pneumocystis pneumonia; hematologic malignancies; treatment outcome; trimethoprim-sulfamethoxazole
3.308
398
Infectious Diseases; Microbiology
Medicine
2,023
35,594,493
Disaggregation of Asian American and Pacific Islander Women With Stage 0-II Breast Cancer Unmasks Disparities in Survival and Surgery-to-Radiation Intervals: A National Cancer Database Analysis From 2004 to 2017.
JCO oncology practice
JCO Oncol Pract
18
8
10.1200/OP.22.00001
eng
2,022
8
null
2,022
5
20
[PURPOSE] Aggregation of Asian Americans (AAs) with Native Hawaiians and Other Pacific Islanders (NHPIs) masks significant health disparities. We evaluated overall survival (OS) and surgery-to-radiation intervals (STRIs) among AA and NHPI women with early-stage breast cancer. [METHODS] This National Cancer Database stu...
null
1.349
85
Health Policy; Oncology; Oncology
Medicine; Nursing
2,022
35,594,361
Association between skeletal muscle changes, anthropometric measurements, and clinical outcomes in critically ill trauma and surgical patients: A prospective observational study.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
Nutr Clin Pract
37
6
10.1002/ncp.10865
eng
2,022
12
null
2,022
5
20
[BACKGROUND] Acute skeletal muscle wasting may predict clinical outcomes in critically ill patients. This study aimed to assess acute muscle loss, changes in anthropometric measurements, and the relationship between muscle loss and clinical outcomes in critically ill trauma and surgical patients. [METHODS] This single-...
anthropometric measurements; clinical outcomes; critical illness; intensive care unit; muscle loss; nutrition status; ultrasound
0.83
94
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
35,593,996
Quantitative detection of methylated SOCS-1 in schizophrenia and bipolar disorder considering SOCS-1 -1478CA/del polymorphism and clinical parameters.
Irish journal of medical science
Ir J Med Sci
192
2
10.1007/s11845-022-03030-w
eng
2,023
4
null
2,022
5
20
[BACKGROUND] We aimed to investigate the quantitative detection of methylated suppressor of cytokine signaling-1 (SOCS-1) in schizophrenia (SCZ) and bipolar disorder (BD), considering SOCS-1 -1478CA/del polymorphism and clinical parameters. [METHODS] Our research is a case-control study in which 114 patients with SCZ, ...
Bipolar disorder; DNA methylation; SOCS-1; Schizophrenia; qMS-PCR
0.532
46
Medicine
Medicine
2,023
35,593,988
AI-based optimization for US-guided radiation therapy of the prostate.
International journal of computer assisted radiology and surgery
Int J Comput Assist Radiol Surg
17
11
10.1007/s11548-022-02664-6
eng
2,022
11
null
2,022
5
20
[OBJECTIVES] Fast volumetric ultrasound presents an interesting modality for continuous and real-time intra-fractional target tracking in radiation therapy of lesions in the abdomen. However, the placement of the ultrasound probe close to the target structures leads to blocking some beam directions. [METHODS] To handle...
Convolutional neural network; Heuristic optimization; Robotic ultrasound; Simulated annealing; Treatment planning
0.831
71
Computer Graphics and Computer-Aided Design; Computer Vision and Pattern Recognition; Radiology, Nuclear Medicine and Imaging; Surgery; Biomedical Engineering; Computer Science Applications; Health Informatics; Medicine
Computer Science; Engineering; Medicine
2,022
35,593,934
Preoperative sarcopenia is a negative predictor for enhanced postoperative recovery after pancreaticoduodenectomy.
Langenbeck's archives of surgery
Langenbecks Arch Surg
407
6
10.1007/s00423-022-02558-w
eng
2,022
9
null
2,022
5
20
[PURPOSE] Sarcopenia is common in pancreatic cancer patients. Considering the growing adoption of standardized protocols for enhanced recovery after surgery (ERAS), we examined the clinical impact of sarcopenia in pancreaticoduodenectomy (PD) patients in a 5-day accelerated ERAS program, termed the Whipple Accelerated ...
ERAS; Pancreatic cancer; Pancreaticoduodenectomy; Sarcopenia; Surgical outcomes
0.721
94
Surgery
Medicine
2,022
35,593,363
Prognostic Signature and Discrimination Signature of Lung Adenocarcinoma based on Pyroptosis-Related Genes.
Combinatorial chemistry high throughput screening
Comb Chem High Throughput Screen
26
2
10.2174/1386207325666220421102117
eng
2,023
null
null
null
null
null
[BACKGROUND] The clinical value of pyroptosis-related genes (PRGs) in lung adenocarcinoma (LUAD) remains obscure. [OBJECTIVE] The study attempts to explore PRGs in LUAD, which will enable an understanding of LUAD from the perspective of PRGs. [METHODS] Lung adenocarcinoma patients were diagnosed using pathology, and th...
Lung adenocarcinoma; immunity; prognosis; pyroptosis-related gene; signature; survival
null
null
null
null
null
35,593,336
Automatic Localization and Identification of Thoracic Diseases from Chest X-rays with Deep Learning.
Current medical imaging
Curr Med Imaging
18
13
10.2174/1573405618666220518110113
eng
2,022
null
null
null
null
null
[BACKGROUND] There are numerous difficulties in using deep learning to automatically locate and identify diseases in chest X-rays (CXR). The most prevailing two are the lack of labeled data of disease locations and poor model transferability between different datasets. This study aims to tackle these problems. [METHODS...
CNN; Chest X-ray; Computer aided diagnosis; Deep learning; Disease localization; Region proposal
0.263
27
Internal Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,593,125
Single intratesticular injection of blood-serum-derived exosomes can potentially alleviate testopathy following testicular torsion.
Animal models and experimental medicine
Animal Model Exp Med
5
4
10.1002/ame2.12232
eng
2,022
12
null
2,022
5
20
[BACKGROUND] Testicular torsion (TT) is an acute inflammatory process leading to male infertility. Today, anti-inflammatory effects of exosomes derived from blood serum are used in various laboratory procedures. In the present study, the anti-inflammatory effects of blood-serum-derived exosomes in treatment of acute in...
anti-inflammation; exosome; parameter; sperm; testicular torsion
null
33
Biochemistry; Medical Laboratory Technology; Medicine; Molecular Biology; Veterinary
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine; Veterinary
2,022
35,593,087
Prevalence and determinants of the involvement of married men in family planning services in Ethiopia: A systematic review and meta-analysis.
Women's health (London, England)
Womens Health (Lond)
18
null
10.1177/17455057221099083
eng
2,022
null
null
null
null
null
[BACKGROUND] Male involvement in family planning includes not only using contraceptives but also encouraging and supporting their partners' contraception needs and choices, encouraging peers to use family planning, and influencing policy to make male-related programs more conducive. In Ethiopia, the prevalence and asso...
Ethiopia; family planning; male involvement; meta-analysis
0.968
56
Medicine
Medicine
2,022
35,592,706
PI3K/AKT/mTOR Pathway-Associated Genes Reveal a Putative Prognostic Signature Correlated with Immune Infiltration in Hepatocellular Carcinoma.
Disease markers
Dis Markers
2022
null
10.1155/2022/7545666
eng
2,022
null
null
2,022
5
9
[BACKGROUND] The dysregulated PI3K/AKT/mTOR pathway acts as the main regulator of tumorigenesis in hepatocellular carcinoma (HCC). [AIM] Here, we identify the prognostic significance of PI3K/AKT/mTOR pathway-associated genes (PAGs) as well as their putative signature based on PAGs in an HCC patient's cohort. [METHODS] ...
null
0.662
85
Biochemistry; Clinical Biochemistry; Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,592,126
Expression of miR-4739 in Gastric cancer and its Relationship with Clinical Pathological Features of Patients.
Frontiers in surgery
Front Surg
9
null
10.3389/fsurg.2022.897583
eng
2,022
null
null
2,022
5
3
[OBJECTIVE] To investigate the expression level of miR-4739 in gastric cancer (GC), analyze its diagnostic value in GC and the relationship with clinical pathological characteristics, and analyze its impact on the prognosis of patients. [METHODS] A total of 96 patients with GC who underwent radical gastrectomy in our h...
clinical features; diagnostic value; gastric cancer; influencing factors; miR-4739; prognosis
0.459
48
Surgery
Medicine
2,022
35,592,099
Controlled Release of TGF-β3 for Effective Local Endogenous Repair in IDD Using Rat Model.
International journal of nanomedicine
Int J Nanomedicine
17
null
10.2147/IJN.S358396
eng
2,022
null
null
2,022
5
9
[INTRODUCTION] Intervertebral disc (IVD) degeneration (IDD) is one of the most widespread musculoskeletal diseases worldwide and remains an intractable clinical challenge. Currently, regenerative strategies based on biomaterials and biological factors to facilitate IVD repair have been widely explored. However, the har...
endogenous repair; hollow manganese dioxide; intervertebral disc degeneration; oxidative stress; transforming growth factor beta-3
1.111
193
Bioengineering; Biomaterials; Biophysics; Drug Discovery; Medicine; Organic Chemistry; Pharmaceutical Science; Nanoscience and Nanotechnology
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Materials Science; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,592,018
Evaluation of Tibial Fixation Devices for Quadrupled Hamstring ACL Reconstruction.
Orthopaedic journal of sports medicine
Orthop J Sports Med
10
5
10.1177/23259671221096107
eng
2,022
5
null
2,022
5
11
[BACKGROUND] Shortcomings to tibial-side fixation have been reported as causes of failure after anterior cruciate ligament reconstruction. Adjustable-loop suspensory devices have become popular; however, no comparison with hybrid fixation (ie, interference screw and cortical button) exists to our knowledge. [PURPOSE] T...
anterior cruciate ligament; biomechanics; fixation; tibia
1.113
68
Orthopedics and Sports Medicine
Medicine
2,022
35,591,977
Phase II study of intravenous etoposide in patients with relapsed ependymoma (CNS 2001 04).
Neuro-oncology advances
Neurooncol Adv
4
1
10.1093/noajnl/vdac053
eng
2,022
null
null
2,022
4
13
[BACKGROUND] Relapsed ependymoma has a dismal prognosis, and the role of chemotherapy at relapse remains unclear. This study prospectively evaluated the efficacy of intensive intravenous (IV) etoposide in patients less than 21 years of age with relapsed intracranial ependymoma (NCT00278252). [METHODS] This was a single...
ependymoma; etoposide; relapse
1.052
33
Neurology; Surgery; Oncology
Medicine
2,022
35,591,906
Relationship Between Four Non-Insulin-Based Indexes of Insulin Resistance and Serum Uric Acid in Patients with Type 2 Diabetes: A Cross-Sectional Study.
Diabetes, metabolic syndrome and obesity : targets and therapy
Diabetes Metab Syndr Obes
15
null
10.2147/DMSO.S362248
eng
2,022
null
null
2,022
5
9
[AIM] The aim of this study was to investigate the association between serum uric acid (SUA) levels and four insulin resistance surrogates in patients with type 2 diabetes (T2DM). The four non-insulin-based indexes of insulin resistance (IR) include the glucose and triglycerides index (TyG), TyG index with body mass in...
METS-IR; TG/HDL-c; TyG; TyG-BMI; insulin resistance; serum uric acid; type 2 diabetes
0.851
71
Internal Medicine; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
35,590,264
Identification and validation of a major QTL for kernel length in bread wheat based on two F3 biparental populations.
BMC genomics
BMC Genomics
23
1
10.1186/s12864-022-08608-3
eng
2,022
5
19
2,022
5
19
[BACKGROUND] High yield and quality are essential goals of wheat (Triticum aestivum L.) breeding. Kernel length (KL), as a main component of kernel size, can indirectly change kernel weight and then affects yield. Identification and utilization of excellent loci in wheat genetic resources is of great significance for c...
F3 biparental populations; Kernel length; QTL identification and validation
1.107
208
Biotechnology; Genetics
Biochemistry, Genetics and Molecular Biology
2,022
35,590,011
Quality of life and secondary outcomes for open versus robot-assisted radical cystectomy: a double-blinded, randomised feasibility trial.
World journal of urology
World J Urol
40
7
10.1007/s00345-022-04029-9
eng
2,022
7
null
2,022
5
20
[PURPOSE] This study aims to examine quality of life (QoL) before and after radical cystectomy (RC) and compare robot-assisted laparoscopy with intracorporeal urinary diversion (iRARC) to open radical cystectomy (ORC). [METHODS] This study is a predefined secondary analysis of a single-centre, double-blinded, randomise...
Bladder cancer; Patient-reported outcomes; Quality of life; Radical cystectomy; Randomised controlled trial; Robotic surgery
1.014
104
Urology
Medicine
2,022
35,589,359
Pandemic impact on patients with advanced non-COVID-19 illness and their family carers receiving specialised palliative home care: a qualitative study.
BMJ open
BMJ Open
12
5
10.1136/bmjopen-2021-059577
eng
2,022
5
19
2,022
5
19
[OBJECTIVES] To investigate the experiential impact of the COVID-19 pandemic on patients with non-COVID, life-threatening disease and their family carers. [DESIGN] An interpretative qualitative design informed by phenomenological hermeneutics and based on data from in-depth interviews, performed between June and Septem...
COVID-19; palliative care; qualitative research
1.059
176
Medicine
Medicine
2,022
35,589,320
Increased Risk of Cardio-Cerebrovascular Diseases in Migraine Patients: A Nationwide Population-Based, Longitudinal Follow-Up Study in South Korea.
Journal of clinical neurology (Seoul, Korea)
J Clin Neurol
18
3
10.3988/jcn.2022.18.3.323
eng
2,022
5
null
null
null
null
[BACKGROUND AND PURPOSE] Migraine is reportedly associated with several cardio-cerebrovascular diseases (CCDs), but some of these diseases have not received sufficient attention. We thus attempted to determine the associations of migraine with peripheral arterial disease (PAD), ischemic heart disease (IHD), atrial fibr...
cardiovascular diseases; cerebrovascular diseases; migraine; stroke
0.1
4
Neurology; Neurology
Medicine; Neuroscience
2,016
35,589,284
Predicting drunk driving using a variant of the implicit association test.
Journal of safety research
J Safety Res
81
null
10.1016/j.jsr.2022.02.005
eng
2,022
6
null
2,022
2
17
[INTRODUCTION] Drunk driving is one of the primary causes of road traffic injuries and fatalities. A possible approach to reduce drunk driving rates is to identify which individuals are at risk of such behavior and establish targeted prevention. Simply asking individuals about drunk driving in real-world contexts would...
Drunk driving; Implicit measures; Past behavior; Prediction
1.109
110
Safety, Risk, Reliability and Quality
Engineering
2,022
35,589,282
A study into the nature and extent of drug driving recidivism in Queensland (Australia).
Journal of safety research
J Safety Res
81
null
10.1016/j.jsr.2022.02.003
eng
2,022
6
null
2,022
2
17
[INTRODUCTION] While research has reported on overall prevalence rates of drug driving, the extent of recidivist offending has yet to be explored. The objective of this research was to examine recidivistic behaviors detected through Roadside Drug Testing (RDT) in Queensland (between December 2007 and June 2020), with a...
Drug driving; Queensland; Recidivism; Roadside drug testing
1.109
110
Safety, Risk, Reliability and Quality
Engineering
2,022
35,601,813
Clinical Experience using Osimertinib in Patients with Recurrent Malignant Gliomas Containing EGFR Alterations.
Journal of cancer science and clinical therapeutics
J Cancer Sci Clin Ther
5
2
10.26502/jcsct.5079114
eng
2,021
null
null
2,021
4
29
[BACKGROUND] EGFR alterations are commonly observed in malignant gliomas (MG). Osimertinib, an irreversible EGFR-tyrosine kinase inhibitor, effectively penetrates the blood brain barrier and achieves therapeutic concentrations in brain tissue. [MATERIALS AND METHODS] This retrospective chart review identified six patie...
Astrocytoma; EGFR; EGFR vIII; GBM; Glioblastoma; Glioma; Osimertinib; Precision oncology; Targeted therapy; Tyrosine kinase inhibitor
null
null
null
null
null
35,591,818
Re-excision within a radius of 2 cm in patients with melanoma of the skin - sufficient for local oncological radicalness.
Archives of medical science : AMS
Arch Med Sci
18
3
10.5114/aoms.2020.97056
eng
2,022
null
null
2,020
7
8
[INTRODUCTION] Malignant melanoma is one of the most malignant tumours in the human body. Radical re-excision of the tumour bed is a principal part of its surgical treatment. We aim to test the hypothesis that the re-excision with a 2 cm margin in all directions to the scar from the previous biopsy of the primary tumou...
local recurrence; malignant melanoma; re-excision
0.799
66
Medicine
Medicine
2,022
35,600,059
Which Patients Are a Better Candidate of Laparoscopic Repair in Obturator Hernia Patients?
Journal of minimally invasive surgery
J Minim Invasive Surg
23
2
10.7602/jmis.2020.23.2.93
eng
2,020
6
15
null
null
null
[PURPOSE] Obturator hernia is a difficult disease to diagnose. If a surgical treatment is delayed in obturator hernia, a bowel resection may be required due to strangulation. The surgical treatment of this disease is to use a classical laparotomy. Recently, the laparoscopic approach has been reported and reviewed for e...
Hernia repair; Laparoscopy; Laparotomies; Obturator hernia
null
null
null
null
null
35,602,998
Comprehensive motor skills assessment in children with autism spectrum disorder yields global deficits.
International journal of developmental disabilities
Int J Dev Disabil
68
3
10.1080/20473869.2020.1764241
eng
2,022
null
null
2,020
5
18
[PURPOSE] Although children with autism spectrum disorder (ASD) often display motor deficits, the nature of these motor deficits remains unspecified. The purpose of this study was to establish a robust motor profile in children with ASD across a wider range of motor skills by using two professionally administered stand...
autism spectrum disorder; balance; coordination; motor proficiency; motor skills
null
null
null
null
null
35,651,912
Copy Number Analyses Identified a Novel Gene: APOBEC3A Related to Lipid Metabolism in the Pathogenesis of Preeclampsia.
Frontiers in cardiovascular medicine
Front Cardiovasc Med
9
null
10.3389/fcvm.2022.841249
eng
2,022
null
null
2,022
5
16
[BACKGROUND] Preeclampsia is a heterogeneous and complex disease with its pathogenesis mechanism not fully elucidated. A certain subset of patients with preeclampsia exhibit disturbances in lipid metabolism before clinical symptoms. Moreover, there is a tendency for preeclampsia to run in families. Whether genetic fact...
APOBEC3A; copy number variation; genetics; lipid metabolism; preeclampsia
1.391
81
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,650,470
The Effect of Standardized Hospitalist Information Cards on the Patient Experience: a Quasi-Experimental Prospective Cohort Study.
Journal of general internal medicine
J Gen Intern Med
37
15
10.1007/s11606-022-07674-3
eng
2,022
11
null
2,022
6
1
[BACKGROUND] Communication with clinicians is an important component of a hospitalized patient's experience. [OBJECTIVE] To test the impact of standardized hospitalist information cards on the patient experience. [DESIGN] Quasi-experimental study in a U.S. tertiary-care center. [PARTICIPANTS] All-comer medicine inpatie...
communication [MeSH]; patient experience; patient satisfaction [MeSH]; patient-centered care [MeSH]; patient-reported outcome measures [MeSH]; physician-patient relations [MeSH]
1.814
224
Internal Medicine
Medicine
2,022
35,650,411
Evaluating the Accuracy of FUCCI Cell Cycle In Vivo Fluorescent Imaging to Assess Tumor Proliferation in Preclinical Oncology Models.
Molecular imaging and biology
Mol Imaging Biol
24
6
10.1007/s11307-022-01739-9
eng
2,022
12
null
2,022
6
1
[PURPOSE] The primary goal of this study is to evaluate the accuracy of the fluorescence ubiquitination cell cycle indicator (FUCCI) system with fluorescence in vivo imaging compared to 3'-deoxy-3'-[[18]F]fluorothymidine ([[18]F]-FLT) positron emission tomography (PET)/computed tomography (CT) and biological validation...
Breast cancer; Cell cycle; Drug screening; Molecular imaging; Proliferative cell imaging; TNBC; [18F]-FLT PET/CT
0.748
81
Oncology; Radiology, Nuclear Medicine and Imaging; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,650,370
The Impact of Low Skeletal Muscle Mass on Short- and Long-Term Outcomes After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.
Annals of surgical oncology
Ann Surg Oncol
29
9
10.1245/s10434-022-11941-2
eng
2,022
9
null
2,022
6
1
[BACKGROUND] Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a potentially curative treatment for peritoneal metastases from colorectal cancer (CRC) or pseudomyxoma peritonei (PMP). Because of the considerable morbidity of this treatment, optimal patient selection is key. This stud...
null
1.133
210
Surgery; Oncology
Medicine
2,022
35,650,020
Injury Precipitating Tissue Loss and Time to Referral to a Vascular Center in Patients with Chronic Limb-Threatening Ischemia.
Journal of atherosclerosis and thrombosis
J Atheroscler Thromb
30
3
10.5551/jat.63593
eng
2,023
3
1
2,022
6
2
[AIM] This study aimed to report injury precipitating tissue loss and to provide updated information on the time from tissue loss occurrence to referral to a vascular center for patients who developed chronic limb-threatening ischemia (CLTI) in Japan. [METHODS] We examined 450 patients who developed CLTI with tissue lo...
Chronic limb-threatening ischemia; Precipitating injury; Severity of tissue loss; Time to referral
1.013
89
Cardiology and Cardiovascular Medicine; Internal Medicine; Biochemistry
Medicine
2,023
35,649,526
Is It All COVID-19? Resident Distress and Reasons for It in 2020.
Southern medical journal
South Med J
115
6
10.14423/SMJ.0000000000001401
eng
2,022
6
null
null
null
null
[OBJECTIVE] For resident wellness, it is important to understand and discern the relative contributions of each factor to resident stress. [METHODS] After institutional review board approval, a 20-question survey instrument was provided to 90 residents across four specialties (Internal Medicine, Emergency Medicine, Gen...
null
null
null
null
null
null
35,649,344
Do Stroke Care Processes Modify Clinical Outcomes in Patients with Stroke-Associated Pneumonia? A Registry Cohort Study in England and Wales.
Cerebrovascular diseases (Basel, Switzerland)
Cerebrovasc Dis
52
1
10.1159/000524917
eng
2,023
null
null
2,022
6
1
[INTRODUCTION] It is not known whether modern stroke unit care reduces the impact of stroke complications, such as stroke-associated pneumonia (SAP), on clinical outcomes. We investigated the relationship between SAP and clinical outcomes, adjusting for the confounding effects of stroke care processes and their timing....
Acute stroke; Clinical outcomes; Cohort study; Stroke complications; Stroke-associated pneumonia
0.7
122
Cardiology and Cardiovascular Medicine; Medicine; Neurology; Neurology
Medicine; Neuroscience
2,023
35,648,432
Effect of Reflectance Confocal Microscopy for Suspect Lesions on Diagnostic Accuracy in Melanoma: A Randomized Clinical Trial.
JAMA dermatology
JAMA Dermatol
158
7
10.1001/jamadermatol.2022.1570
eng
2,022
7
1
null
null
null
[IMPORTANCE] Previous systematic reviews and meta-analyses have concluded that given data paucity, a comparison of reflectance confocal microscopy (RCM) with dermoscopy is complex. They recommend comparative prospective studies in a real-world setting of suspect lesions. [OBJECTIVE] To test the hypothesis that RCM redu...
null
null
null
null
null
null