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35,622,160
Local resection versus radical resection for early-stage rectal cancer: a systematic review and meta-analysis.
International journal of colorectal disease
Int J Colorectal Dis
37
7
10.1007/s00384-022-04186-8
eng
2,022
7
null
2,022
5
27
[PURPOSE] The optimal surgical approach for early-stage rectal cancer remains controversial. Radical resection is considered to be the gold standard for rectal cancer treatment. More and more studies show that local resection can replace traditional radical resection in the treatment of early rectal cancer. This resear...
Early low rectal cancer; Local resection; Meta-analysis; Radical resection; Systems review
0.813
103
Gastroenterology
Medicine
2,022
35,622,149
Discussing POLST-facilitated hospice care enrollment in patients with terminal cancer.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
30
9
10.1007/s00520-022-07143-x
eng
2,022
9
null
2,022
5
27
[PURPOSE] A multicenter prospective study to evaluate the feasibility of Physician Orders for Life-Sustaining Treatment (POLST) in oncology practice was conducted between June and December 2017. Factors associated with POLST completion and follow-up outcomes were analyzed. [METHODS] Patients with terminal cancer, aged ...
Hospices; Out-of-hospital death; POLST; Terminal cancer
0.984
143
Oncology
Medicine
2,022
35,621,916
6- and 12-Month Outcomes after 90:10 Enteral Nutrition Induction Therapy in Pediatric Crohn's Disease.
Journal of pediatric gastroenterology and nutrition
J Pediatr Gastroenterol Nutr
75
1
10.1097/MPG.0000000000003475
eng
2,022
7
1
2,022
5
27
[OBJECTIVES] Studies describing longer-term outcomes after EEN induction are limited. We describe clinical outcomes during 90:10 EN induction, and 6- and 12- month outcomes among patients that successfully completed EN induction and then continued either EN or immunomodulator (IM) maintenance therapy. [METHODS] All chi...
null
0.868
160
Pediatrics, Perinatology and Child Health; Gastroenterology
Medicine
2,022
35,620,861
Proteomics endotyping of infants with severe bronchiolitis and risk of childhood asthma.
Allergy
Allergy
77
11
10.1111/all.15390
eng
2,022
11
null
2,022
6
5
[BACKGROUND] Bronchiolitis is the leading cause of hospitalization in U.S. infants and a major risk factor for childhood asthma. Growing evidence supports clinical heterogeneity within bronchiolitis. We aimed to identify endotypes of infant bronchiolitis by integrating clinical, virus, and serum proteome data, and exam...
asthma; bronchiolitis; endotyping; infants; proteome
2.734
213
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
35,620,825
A Single Baseline Amyloid Positron Emission Tomography Could Be Sufficient for Predicting Alzheimer's Disease Conversion in Mild Cognitive Impairment.
Psychiatry investigation
Psychiatry Investig
19
5
10.30773/pi.2022.0014
eng
2,022
5
null
2,022
5
23
[OBJECTIVE] Baseline amyloid burden in mild cognitive impairment (MCI) has been linked to conversion to Alzheimer's disease (AD), but the comparison of baseline and longitudinal changes in amyloid burden for predicting AD remains unresolved. The objectives of this study aimed to compare the prognostic ability of baseli...
Amyloid burden; Longitudinal; Mild cognitive impairment; Prediction
0.716
57
Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience
2,022
35,620,804
Dining on the dead in the deep: Active NH4 [+] excretion via Na[+] /H[+] (NH4 [+]) exchange in the highly ammonia tolerant Pacific hagfish, Eptatretus stoutii.
Acta physiologica (Oxford, England)
Acta Physiol (Oxf)
236
2
10.1111/apha.13845
eng
2,022
10
null
2,022
6
24
[AIM] Pacific hagfish are exceptionally tolerant to high environmental ammonia (HEA). Here, we elucidated a cellular mechanism that enables hagfish to actively excrete ammonia against steep ammonia gradients expected to be found inside a decomposing whale carcass. [METHODS] Hagfish were exposed to varying concentration...
Agnatha; Na+/H+ exchanger; Na+/NH4+ exchange; ammonium; gill; high environmental ammonia; nitrogen; rhesus glycoprotein
1.497
135
Physiology
Biochemistry, Genetics and Molecular Biology
2,022
35,620,728
An In Vitro Pilot Study on the Effects of Silver Diamine Fluoride on Periodontal Pathogens and Three-Dimensional Scaffolds of Human Fibroblasts and Epithelial Cells.
International journal of dentistry
Int J Dent
2022
null
10.1155/2022/9439096
eng
2,022
null
null
2,022
5
17
[OBJECTIVE] The aims of this study were to investigate the antibacterial and cytotoxic effects of silver diamine fluoride (SDF) on periodontal pathogens and human skin constructs, respectively. [BACKGROUND] SDF has been proven to have bactericidal effects on cariogenic bacteria. No studies to date evaluated the bacteri...
null
0.47
57
Dentistry
Dentistry
2,022
35,620,659
Association between total type I collagen N-terminal propeptide and coronary artery disease risk score in the general Japanese population.
International journal of cardiology. Heart & vasculature
Int J Cardiol Heart Vasc
41
null
10.1016/j.ijcha.2022.101056
eng
2,022
8
null
2,022
5
19
[BACKGROUND] Bone metabolic dysregulation plays an important role in the pathogenesis of atherosclerosis; however, whether its markers contribute to coronary artery disease (CAD) risk in the general population remains unclear. Therefore, this study aimed to analyze the association between bone metabolic markers and CAD...
Bone-type alkaline phosphatase; Suita score; cross-linked N-telopeptide of type 1 collagen; intact Parathyroid hormone
null
null
null
null
null
35,620,535
Perioperative intravenous iron to treat patients with fractured hip surgery: A systematic review and meta-analysis.
Health science reports
Health Sci Rep
5
3
10.1002/hsr2.633
eng
2,022
5
null
2,022
5
22
[BACKGROUND] Treatment of preoperative anemia with intravenous iron is common within elective surgical care pathways. It is plausible that this treatment may improve care for people with hip fractures many of whom are anemic because of pre-existing conditions, fractures, and surgery. [OBJECTIVE] To review the evidence ...
anemia; hip fracture; intravenous iron
0.543
26
Medicine
Medicine
2,022
35,619,657
Are tri-pronuclear embryos that show two normal-sized pronuclei and additional smaller pronuclei useful for embryo transfer?
Reproductive medicine and biology
Reprod Med Biol
21
1
10.1002/rmb2.12462
eng
2,022
null
null
2,022
5
23
[PURPOSE] This study aimed to analyze whether tripronuclear (3PN) zygotes, with two normal-sized PNs and an additional smaller PN (2.1PN), can be used for embryo transfer. [METHODS] A retrospective embryo cohort study was conducted on 695 patients who underwent intracytoplasmic sperm injection treatment. Blastocyst for...
ICSI; aneuploidy; embryo; ploidy; tripronuclear zygote
0.778
42
Reproductive Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,619,612
From Perceived Stress to Demoralization in Parkinson Disease: A Path Analysis.
Frontiers in psychiatry
Front Psychiatry
13
null
10.3389/fpsyt.2022.876445
eng
2,022
null
null
2,022
5
10
[OBJECTIVES] The objective of this study was to determine whether depression and anxiety are mediators between perceived stress and demoralization via a loss of the cognitive map to get out of the predicament manifesting as subjective incompetence. [METHODS] Ninety-five consecutive outpatients with Parkinson's disease ...
Parkinson's disease; anxiety; demoralization; depression; stress; subjective incompetence; suicide/suicidal ideation/suicidal behavior
1.222
134
Psychiatry and Mental Health
Medicine
2,022
35,619,584
SOX12 Promotes Thyroid Cancer Cell Proliferation and Invasion by Regulating the Expression of POU2F1 and POU3F1.
Yonsei medical journal
Yonsei Med J
63
6
10.3349/ymj.2022.63.6.591
eng
2,022
6
null
null
null
null
[PURPOSE] SOX12 is overexpressed in many cancers, and we aimed to explore the biological function and mechanism of SOX12 in thyroid cancer. [MATERIALS AND METHODS] We first analyzed the expression of SOX12 in thyroid cancer using data in The Cancer Genome Atlas. Immunohistochemistry and qRT-PCR were performed to identi...
POU family; SOX12; Thyroid cancer; cell proliferation; invasion
0.57
78
Medicine
Medicine
2,022
35,619,547
Poor inter-observer agreement in anatomical classifications of infrapopliteal arterial disease due to mandatory selection of only one target artery.
Acta radiologica (Stockholm, Sweden : 1987)
Acta Radiol
64
3
10.1177/02841851221102788
eng
2,023
3
null
2,022
5
26
[BACKGROUND] Established anatomical classifications of infrapopliteal arterial lesion severity are based on assessment of only one target artery, not including all infrapopliteal arteries although multivessel revascularization is common. [PURPOSE] To investigate the reproducibility of one of these classifications and a...
Peripheral arterial disease; anatomical classification; digital subtraction angiography; endovascular procedures; infrapopliteal; magnetic resonance angiography
0.429
82
Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine
2,023
35,619,158
Human umbilical cord mesenchymal stem cells-derived exosomes for treating traumatic pancreatitis in rats.
Stem cell research & therapy
Stem Cell Res Ther
13
1
10.1186/s13287-022-02893-1
eng
2,022
5
26
2,022
5
26
[BACKGROUND] The therapeutic and protective effects of human umbilical cord mesenchymal stem cells-exosomes (hucMSC-Exs) on traumatic pancreatitis (TP) remain unknown. Here, we established a rat model of TP and evaluated and compared the therapeutic effects of hUC-MSCs and hucMSC-Exs. [METHODS] HucMSC-Exs were obtained...
Apoptosis; Exosomes; Human umbilical cord mesenchymal stem cells; Inflammation; Therapeutic effect; Traumatic pancreatitis
null
null
null
null
null
35,619,121
"I have such a hard time hitting myself, I thought it'd be easier": perspectives of hospitalized patients on injecting drugs into vascular access devices.
Harm reduction journal
Harm Reduct J
19
1
10.1186/s12954-022-00637-1
eng
2,022
5
26
2,022
5
26
[BACKGROUND] Hospital patients who use drugs may require prolonged parenteral antimicrobial therapy administered through a vascular access device (VAD). Clinicians' concerns that patients may inject drugs into these devices are well documented. However, the perspectives of patients on VAD injecting are not well describ...
Harm reduction; Hospitalization; Patient-centered care; Substance-related disorders; Vascular access devices
1.414
71
Medicine; Psychiatry and Mental Health; Public Health, Environmental and Occupational Health
Medicine
2,022
35,618,716
A comparison of trueness and precision of 12 3D printers used in dentistry.
BDJ open
BDJ Open
8
1
10.1038/s41405-022-00108-6
eng
2,022
5
26
2,022
5
26
[INTRODUCTION] Judging the dimensional accuracy of the resulting printed part requires comparison and conformity between the 3D printed model and its virtual counterpart. The resolution and accuracy of 3D model samples are determined by a wide array of factors depending on the technology used and related factors such a...
null
0.859
17
Dentistry
Dentistry
2,022
35,618,645
Five-year weight loss, physical activity, and eating style trajectories after bariatric surgery.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
Surg Obes Relat Dis
18
7
10.1016/j.soard.2022.03.020
eng
2,022
7
null
2,022
4
11
[BACKGROUND] Little research has taken individual variability in weight loss into account. Furthermore, physical activity (PA) and eating style (ES) have been linked only sporadically to weight loss longitudinally. [OBJECTIVES] Identify and describe latent classes of weight loss, change of PA, and change of ES up to 5 ...
Eating style; Long-term follow-up; Physical activity; Roux-en-Y gastric bypass; Sleeve gastrectomy; Weight loss trajectories
1.219
113
Surgery
Medicine
2,022
35,618,555
Intraocular reflectance of the ocular fundus and its impact on increased retinal hazard.
Zeitschrift fur medizinische Physik
Z Med Phys
32
4
10.1016/j.zemedi.2022.03.001
eng
2,022
11
null
2,022
5
23
[PURPOSE] Inside the eye light can be reflected multiple times due to light-tissue interactions and the spherical geometry of the eye. Due to these optical properties, a defined retinal area is not only illuminated by direct light but also by indirect, reflected light from the inner side of the eyewall. During illumina...
Intraocular illumination; Photochemical hazard; Pigmentation; Reflectance; Retinal hazard; Thermal hazard
1.154
43
Biophysics; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine
2,022
35,618,322
A combined application of molecular docking technology and indirect ELISA for the serodiagnosis of bovine tuberculosis.
Journal of veterinary science
J Vet Sci
23
3
10.4142/jvs.21270
eng
2,022
5
null
null
null
null
[BACKGROUND] There is an urgent need to find reliable and rapid bovine tuberculosis (bTB) diagnostics in response to the rising prevalence of bTB worldwide. Toll-like receptor 2 (TLR2) recognizes components of bTB and initiates antigen-presenting cells to mediate humoral immunity. Evaluating the affinity of antigens wi...
Bovine tuberculosis; enzyme-linked immunosorbent assay; molecular docking; recombinant proteins; toll-like receptor 2
0.403
59
Veterinary
Veterinary
2,022
35,677,265
The prospective study of change of perception of postgraduate students on objective structured clinical examination in burns and plastic surgery.
Journal of education and health promotion
J Educ Health Promot
11
null
10.4103/jehp.jehp_592_21
eng
2,022
null
null
2,022
4
28
[BACKGROUND] In this study, we attempted to assess the change of perception of postgraduate students on objective structured clinical examination (OSCE) in burns and plastic surgery after first five OSCE. [METHODS] A prevalidated feedback questionnaire was used to assess and score the perception of postgraduate student...
Clinical examination; examination assessment tool; objective structured
0.411
30
Education; Medicine
Medicine; Social Sciences
2,022
35,676,813
Inhibition of Ciliogenesis Enhances the Cellular Sensitivity to Temozolomide and Ionizing Radiation in Human Glioblastoma Cells.
Biomedical and environmental sciences : BES
Biomed Environ Sci
35
5
10.3967/bes2022.058
eng
2,022
5
20
null
null
null
[OBJECTIVE] To investigate the function of primary cilia in regulating the cellular response to temozolomide (TMZ) and ionizing radiation (IR) in glioblastoma (GBM). [METHODS] GBM cells were treated with TMZ or X-ray/carbon ion. The primary cilia were examined by immunostaining with Arl13b and γ-tubulin, and the cellul...
Autophagy; Cellular sensitivity; DNA damage response; DNA-PK; Glioblastoma; Ionizing radiation; Primary cilia; Temozolomide
null
null
null
null
null
35,676,808
Obesity-associated metabolites in relation to type 2 diabetes risk: A prospective nested case-control study of the CARRS cohort.
Diabetes, obesity & metabolism
Diabetes Obes Metab
24
10
10.1111/dom.14788
eng
2,022
10
null
2,022
7
5
[AIMS] To determine whether obesity-associated metabolites are associated with type 2 diabetes (T2DM) risk among South Asians. [MATERIALS AND METHODS] Serum-based nuclear magnetic resonance imaging metabolomics data were generated from two South Asian population-based prospective cohorts from Karachi, Pakistan: CARRS1 ...
body composition; cohort study; dyslipidaemia; observational study; population study; type 2 diabetes
null
null
null
null
null
35,676,723
Assessment of biosafety and toxicity of hydrophilic gel for implantation in experimental in vitro and in vivo models.
BMC pharmacology & toxicology
BMC Pharmacol Toxicol
23
1
10.1186/s40360-022-00577-3
eng
2,022
6
8
2,022
6
8
[BACKGROUND] The assessment of biosafety of pharmacologically active substances is crucial for determining the feasibility of their medical use. There are controversial issues regarding the use of substances of different origins as implants. [METHODS] We have conducted the comprehensive studies to determine the in vivo...
Experimental model systems; Genotoxicity; Hydrophilic gel for implantation; In vitro and in vivo studies; Toxicity
null
null
null
null
null
35,676,708
The effect of the Baduanjin exercise on COVID-19-related anxiety, psychological well-being and lower back pain of college students during the pandemic.
BMC sports science, medicine & rehabilitation
BMC Sports Sci Med Rehabil
14
1
10.1186/s13102-022-00493-3
eng
2,022
6
8
2,022
6
8
[BACKGROUND] This study aimed to examine the effect of Baduanjin exercise on COVID-19-related anxiety, psychological well-being, and the lower back pain of college students during the coronavirus pandemic in China. [SETTING] The study was carried out in a temporary experimental center of four universities in Wenzhou ci...
Baduanjin exercise; COVID-19-related anxiety; College student; Mental health; Pandemic; Qigong; The prevalence of low back pain
null
null
null
null
null
35,676,686
Women's attitude towards intimate partner violence and utilization of contraceptive methods and maternal health care services: an analysis of nationally representative cross-sectional surveys from four South Asian countries.
BMC women's health
BMC Womens Health
22
1
10.1186/s12905-022-01780-4
eng
2,022
6
8
2,022
6
8
[BACKGROUND] Intimate partner violence (IPV) adversely affects women's reproductive health outcomes but to what extent women's justification of IPV affects maternal health care service utilization is unexplored. [METHODS] The secondary cross-sectional datasets from multiple indicator cluster surveys of Afghanistan, Bhu...
Antenatal care; Contraceptive methods; Institutional delivery and post-natal care; Intimate partner violence
0.775
73
Medicine; Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,022
35,676,622
Social contact impacts physical activity and sedentary behavior among older adults in Japan due to COVID-19.
BMC geriatrics
BMC Geriatr
22
1
10.1186/s12877-022-03188-z
eng
2,022
6
8
2,022
6
8
[BACKGROUND] The coronavirus disease 2019 (COVID-19) has adversely affected social contact and physical activity. This study investigated the correlation between physical activity, social contact, and sedentary time among adults aged 65 years and above during the COVID-19 pandemic. [METHODS] This study was conducted in...
Aging; Physical activity; SARS-Cov-2 outbreak; Sitting time; Social capital
1.127
112
Geriatrics and Gerontology
Medicine
2,022
35,676,603
Predictors of Sentinel Lymph Node Metastasis in Patients with Thin Melanoma: An International Multi-institutional Collaboration.
Annals of surgical oncology
Ann Surg Oncol
29
11
10.1245/s10434-022-11936-z
eng
2,022
10
null
2,022
6
8
[BACKGROUND] Consideration of sentinel lymph node biopsy (SLNB) is recommended for patients with T1b melanomas and T1a melanomas with high-risk features; however, the proportion of patients with actionable results is low. We aimed to identify factors predicting SLNB positivity in T1 melanomas by examining a multi-insti...
null
1.133
210
Surgery; Oncology
Medicine
2,022
35,676,012
Comparison of biodegradable and durable polymer drug-eluting stents in acute coronary syndrome: a meta-analysis.
BMJ open
BMJ Open
12
6
10.1136/bmjopen-2021-058075
eng
2,022
6
8
2,022
6
8
[OBJECTIVE] To compare the safety and effectiveness between biodegradable polymer drug-eluting stents (BP-DES) and durable polymer drug-eluting stents (DP-DES) in patients with acute coronary syndrome (ACS). [DESIGN] Meta-analysis of randomised controlled trials (RCTs). [PRIMARY AND SECONDARY OUTCOME MEASURES] Major ad...
Coronary heart disease; Coronary intervention; Myocardial infarction
1.059
176
Medicine
Medicine
2,022
35,675,860
The comparison of preliminary structure and intestinal anti-inflammatory and anti-oxidative activities of polysaccharides from different root parts of Angelica sinensis (Oliv.) Diels.
Journal of ethnopharmacology
J Ethnopharmacol
295
null
10.1016/j.jep.2022.115446
eng
2,022
9
15
2,022
6
5
[ETHNOPHARMACOLOGICAL RELEVANCE] The root of Angelica sinensis, has been commonly used in gynecology for centuries, and is normally applied divided into different parts in various clinical applications. At present, the majority of existing studies focus on the volatile oil and ferulic acid extracted from different part...
Angelica sinensis polysaccharides; Anti-inflammatory effect; Anti-oxidative effect; Different plant parts; Pectin
0.833
243
Drug Discovery; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,022
35,675,790
Factors Associated with Severity of Acute Kidney Injury and Adverse Outcomes in Critically Ill Patients with COVID-19.
Nephron
Nephron
146
6
10.1159/000524657
eng
2,022
null
null
2,022
6
8
[BACKGROUND] Acute kidney injury (AKI) is a well-recognized complication of coronavirus disease 2019 (COVID-19). The short and long-term outcomes of patients who develop AKI have not been well characterized. [METHODS] In this multicenter retrospective cohort study, we describe the clinical characteristics and outcomes ...
Acute kidney injury; Body mass index; Coronavirus disease 2019; Critical illness; Severe acute respiratory coronavirus 2
0.783
102
Urology; Medicine; Nephrology; Physiology; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,675,739
The combined effect of anemia and dynapenia on mortality risk in older adults: 10-Year evidence from the ELSA cohort study.
Archives of gerontology and geriatrics
Arch Gerontol Geriatr
102
null
10.1016/j.archger.2022.104739
eng
2,022
null
null
2,022
6
1
[BACKGROUND/OBJECTIVE] Anemia and dynapenia can occur simultaneously. Separately, both conditions increase the mortality risk with advancing age. However, there is no epidemiological evidence on the combined effect of these conditions on mortality in older adults. We investigated whether combined anemia and dynapenia i...
Anemia; Dynapenia; Handgrip strength; Hemoglobin levels; Mortality
1.008
102
Gerontology; Health; Aging; Geriatrics and Gerontology
Biochemistry, Genetics and Molecular Biology; Medicine; Nursing; Social Sciences
2,022
35,675,706
Factors Causing Variation in World Health Organization Surgical Safety Checklist Effectiveness-A Rapid Scoping Review.
Journal of patient safety
J Patient Saf
18
8
10.1097/PTS.0000000000001035
eng
2,022
12
1
2,022
6
9
[INTRODUCTION] This review was conducted to determine what factors might be responsible for prejudicing the outcomes after the implementation of a World Health Organization Surgical Safety Checklist (WHO SSC), grouping them appropriately and proposing strategies that enable the SSC a more helpful and productive tool in...
null
0.578
49
Leadership and Management; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,022
35,675,608
Comprehension of an Over-the-Counter Drug Facts Label Prototype for a Mifepristone and Misoprostol Medication Abortion Product.
Obstetrics and gynecology
Obstet Gynecol
139
6
10.1097/AOG.0000000000004757
eng
2,022
6
1
2,022
5
2
[OBJECTIVE] To develop a drug facts label prototype for a combination mifepristone and misoprostol product and to conduct a label-comprehension study to assess understanding of key label concepts. [METHODS] We followed U.S. Food and Drug Administration guidance, engaged a multidisciplinary group of experts, and conduct...
null
2.48
268
Obstetrics and Gynecology
Medicine
2,022
35,675,329
Sex disparities and the risk of urolithiasis: a large cross-sectional study.
Annals of medicine
Ann Med
54
1
10.1080/07853890.2022.2085882
eng
2,022
12
null
null
null
null
[BACKGROUND] Urolithiasis is one of the most common diseases in urology, with a lifetime prevalence of 14% and is more prevalent in males compared to females. We designed to explore sex disparities in the Chinese population to provide evidence for prevention measures and mechanisms of stone formation. [MATERIALS AND ME...
China; Urolithiasis; age; cross-sectional study; sex difference
1.052
133
Medicine
Medicine
2,022
35,675,081
Emergency vs Delayed Coronary Angiogram in Survivors of Out-of-Hospital Cardiac Arrest: Results of the Randomized, Multicentric EMERGE Trial.
JAMA cardiology
JAMA Cardiol
7
7
10.1001/jamacardio.2022.1416
eng
2,022
7
1
null
null
null
[IMPORTANCE] Although an emergency coronary angiogram (CAG) is recommended for patients who experience an out-of-hospital cardiac arrest (OHCA) with ST-segment elevation on the postresuscitation electrocardiogram (ECG), this strategy is still debated in patients without ST-segment elevation. [OBJECTIVE] To assess the 1...
null
7.371
127
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,673,822
Role of ProEx C immunocytochemistry in cervical high-grade squamous intraepithelial lesions detection.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Rom J Morphol Embryol
62
4
10.47162/RJME.62.4.15
eng
2,021
null
null
null
null
null
[BACKGROUND] Screening programs using Papanicolaou smear along with human papillomavirus (HPV) testing led to a significantly decrease of cervical cancer rates. Nevertheless, both assessments have limited specificity for revealing cervical high-grade lesions. The main problem is how to identify the real precursor of ce...
null
null
null
null
null
null
35,673,650
Application of the subdural evacuating port system for the drainage of postoperative tension pneumocephalus: A technical note.
Surgical neurology international
Surg Neurol Int
13
null
10.25259/SNI_120_2022
eng
2,022
null
null
2,022
5
20
[BACKGROUND] Tension pneumocephalus is a neurosurgical emergency requiring prompt intervention. A variety of either temporizing or definitive methods was previously described as part of its management. Here, we report on an off-label use of a bed-side device and the subdural evacuating port system (SEPS)™ for the treat...
Brain compression; Burr hole; Craniotomy; Subdural evacuating port system; Tension pneumocephalus
0.256
48
Surgery; Neurology
Medicine
2,022
35,673,548
Automatic Detection of Severely and Mildly Infected COVID-19 Patients with Supervised Machine Learning Models.
Ingenierie et recherche biomedicale : IRBM = Biomedical engineering and research
Ing Rech Biomed
44
1
10.1016/j.irbm.2022.05.006
eng
2,023
2
null
2,022
6
1
[OBJECTIVES] When the prognosis of COVID-19 disease can be detected early, the intense-pressure and loss of workforce in health-services can be partially reduced. The primary-purpose of this article is to determine the feature-dataset consisting of the routine-blood-values (RBV) and demographic-data that affect the pro...
Biochemical and hematological biomarkers; COVID-19; Classification; Feature selection methods; Routine blood values; Supervised machine learning models
null
null
null
null
null
35,673,474
Putative effect of melatonin on cardiomyocyte senescence in mice with type 1 diabetes mellitus.
Journal of diabetes and metabolic disorders
J Diabetes Metab Disord
21
1
10.1007/s40200-022-00982-9
eng
2,022
6
null
2,022
1
31
[BACKGROUND] To date, many investigators have tried to clarify the molecular mechanism of cardiovascular injuries after T1D. In present study, we evaluated the possible effects of melatonin on the levels of aging-related factors in the heart tissue of streptozotocin-induced diabetic mice. [METHODS] 40 male mice were en...
Aging; Cardiac tissue; Inflammation; Melatonin; Pathological changes; Type 1 diabetes mellitus
0.65
49
Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,022
35,673,441
Development and evaluation of a new questionnaire to assess social cognitive factors of self-management in patients with type 2 diabetes: a psychometric study.
Journal of diabetes and metabolic disorders
J Diabetes Metab Disord
21
1
10.1007/s40200-022-00999-0
eng
2,022
6
null
2,022
2
9
[BACKGROUND] Self-care behaviors are essential to control blood sugar and to prevent mortality and complications of diabetes. The evidence suggests that social cognitive factors play a crucial role in adopting self-care behaviors. This study aimed to develop and examine the psychometric properties of the Diabetes Self-...
Diabetes; Factor analysis; HbA1c; Psychometric; SCT; Self-Management
0.65
49
Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,022
35,673,412
The predictors of the use of complementary and alternative medicine among type 2 diabetes patients based on the health belief model.
Journal of diabetes and metabolic disorders
J Diabetes Metab Disord
21
1
10.1007/s40200-022-00971-y
eng
2,022
6
null
2,022
1
11
[OBJECTIVE] The aim of this study was to determine the predictors of the use of complementary and alternative medicine (CAM) in patients with type 2 diabetes based on the health belief model (HBM). [METHODS] This cross-sectional study was performed in 2019 (from April to September) on 837 type 2 diabetic patients by mu...
CAM; Complementary and alternative medicine; HBM; Health belief model; Type 2 diabetes
0.65
49
Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,022
35,672,868
Worsening or improving hypoalbuminemia during continuous renal replacement therapy is predictive of patient outcome: a single-center retrospective study.
Journal of intensive care
J Intensive Care
10
1
10.1186/s40560-022-00620-9
eng
2,022
6
7
2,022
6
7
[BACKGROUND] Hypoalbuminemia at the initiation of continuous renal replacement therapy (CRRT) is a risk factor for poor patient outcomes. However, it is unknown whether the patterns of changes in serum albumin levels during CRRT can be used to predict patient outcomes. [METHODS] This retrospective study analyzed data t...
Acute kidney injury; Albumin; Continuous renal replacement therapy; Hypoalbuminemia
1.452
59
Critical Care and Intensive Care Medicine
Medicine
2,022
35,672,818
Effect of enamel-surface modifications on shear bond strength using different adhesive materials.
BMC oral health
BMC Oral Health
22
1
10.1186/s12903-022-02254-7
eng
2,022
6
7
2,022
6
7
[BACKGROUND] This study aimed to investigate the effect of enamel-surface modifications on the shear bond strength between ceramic brackets bonded using different adhesive materials and the enamel surface and to identify the most suitable clinical adhesive and bonding method. Whether the non-acid-etching treatment met ...
Ceramic brackets; Resin-modified glass ionomer cement; Shear bond strength; Surface treatments
0.741
80
Dentistry
Dentistry
2,022
35,672,812
Hand-assisted laparoscopic resection versus total laparoscopic gastric surgery for primary gastric gastrointestinal stromal tumors (GISTs): an analysis from a high-volume institution.
BMC surgery
BMC Surg
22
1
10.1186/s12893-022-01668-y
eng
2,022
6
7
2,022
6
7
[BACKGROUND] Laparoscopic resection of gastric gastrointestinal stromal tumors (GISTs) is technically feasible and associated with favorable outcomes. We compared the clinical efficacy of hand-assisted laparoscopic surgery (HLS) and total laparoscopic surgery (TLS) for gastric GISTs. [METHODS] We retrospectively analyz...
Gastric GIST; Hand-assisted laparoscopic surgery; Surgical outcome; Total laparoscopic surgery
0.502
64
Surgery; Medicine
Medicine
2,022
35,672,168
Interfacility helicopter transport to a tertiary pediatric trauma center.
Journal of pediatric surgery
J Pediatr Surg
57
11
10.1016/j.jpedsurg.2022.05.010
eng
2,022
11
null
2,022
5
16
[BACKGROUND] Helicopter emergency medical services (HEMS) are intended to expedite care to definitive management. Studies are inconclusive in demonstrating appropriate use. We aimed to examine emergent interventions after interfacility helicopter transport (IHT) to our pediatric trauma center. [METHODS] Trauma patients...
Critical care; General surgery; Pediatrics; Transportation
0.873
147
Medicine; Pediatrics, Perinatology and Child Health; Surgery
Medicine
2,022
35,671,304
A qualitative photo-elicitation study exploring the impact of falls and fall risk on individuals with subacute spinal cord injury.
PloS one
PLoS One
17
6
10.1371/journal.pone.0269660
eng
2,022
null
null
2,022
6
7
[BACKGROUND] Individuals living with chronic spinal cord injury or disease (SCI/D) are at an increased risk of falling. However, little is known about the impact of falls and fall risk in the subacute phase of SCI/D, despite this being a time when fall prevention initiatives are delivered. Hence, we explored the impact...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
35,671,048
Effect of SPARC Suppression in Mice, Perfused Human Anterior Segments, and Trabecular Meshwork Cells.
Investigative ophthalmology visual science
Invest Ophthalmol Vis Sci
63
6
10.1167/iovs.63.6.8
eng
2,022
6
1
null
null
null
[PURPOSE] Secreted protein, acidic and rich in cysteine (SPARC) elevates intraocular pressure (IOP), increases certain structural extracellular matrix (ECM) proteins in the juxtacanalicular trabecular meshwork (JCT), and decreases matrix metalloproteinase (MMP) protein levels in trabecular meshwork (TM) endothelial cel...
null
null
null
null
null
null
35,670,921
Evaluation of placental growth potential and placental bed perfusion by 3D ultrasound for early second-trimester prediction of preeclampsia.
Journal of assisted reproduction and genetics
J Assist Reprod Genet
39
7
10.1007/s10815-022-02530-z
eng
2,022
7
null
2,022
6
7
[PURPOSE] This study aimed to investigate whether placental parameters measured by three-dimensional ultrasound are associated with preeclampsia (PE) and small-for-gestational-age (SGA). [METHODS] In total, 1163 pregnancies at 11-14 weeks of gestation were recruited between October 8, 2020, and April 30, 2021. Placenta...
Early-onset preeclampsia; Placental bed; Preeclampsia; Three-dimensional ultrasound, Placental volume; Vascularization flow index
0.844
101
Developmental Biology; Genetics; Genetics; Medicine; Obstetrics and Gynecology; Reproductive Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,670,748
Press tack needle stimulation for blunt chest trauma: a randomized double-blind control trial.
Interactive cardiovascular and thoracic surgery
Interact Cardiovasc Thorac Surg
35
1
10.1093/icvts/ivac158
eng
2,022
6
15
null
null
null
[OBJECTIVES] Blunt chest trauma is often associated with severe pain, reduced lung function and decreased sleep quality. This study aims to investigate the immediate and long-term effect of acupuncture on these factors using a randomized control double-blind design. [METHODS] A total of 72 patients were randomized into...
Acupuncture; Analgesia; Blunt chest trauma; Press tack needles; Rib fracture
0.538
76
Cardiology and Cardiovascular Medicine; Surgery; Pulmonary and Respiratory Medicine
Medicine
2,022
35,670,533
Long-term use of ospemifene in clinical practice for vulvo-vaginal atrophy: end results at 12 months of follow-up.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Gynecol Endocrinol
38
7
10.1080/09513590.2022.2083103
eng
2,022
7
null
2,022
6
7
[OBJECTIVE] To assess the improvement in vulvovaginal atrophy (VVA) of postmenopausal women treated with oral ospemifene 60 mg/day under conditions of routine clinical practice after 12 months of follow-up. [METHODS] The AYSEX study is a Spanish observational, prospective, and unicentric study in which five gynecologis...
Ospemifene; clinical practice; dyspareunia; endometrial thickness; sexual function
0.562
79
Obstetrics and Gynecology; Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,670,227
Prevalence and Causes of Visual Impairment and Blindness in Elderly Population; an Urgent Geriatric Health Issue: Tehran Geriatric Eye Study (TGES).
Ophthalmic epidemiology
Ophthalmic Epidemiol
30
3
10.1080/09286586.2022.2085304
eng
2,023
6
null
2,022
6
7
[PURPOSE] To determine the prevalence of vision impairment (VI) and blindness and their determinants in the elderly population of Tehran. [METHODS] In a cross-sectional study, multi-stage cluster sampling was used to select a sample of over 60 year population of Tehran. Optometric examinations included the measurement ...
Visual impairment; blindness; cataract; elderly population; uncorrected refractive errors
0.981
78
Ophthalmology; Epidemiology
Medicine
2,023
35,670,212
The disproportionately large contribution of the Māori and Pacific Islander community to the healthcare burden of gout in Western Sydney.
Internal medicine journal
Intern Med J
53
8
10.1111/imj.15831
eng
2,023
8
null
2,022
7
10
[BACKGROUND] Gout is a common chronic inflammatory disorder due to monosodium urate deposition, which results in severe inflammatory arthritis. It is particularly common in those of Māori or Pacific Islander heritage. There is a significant number of this at-risk ethnic group in western Sydney. [AIMS] To determine the ...
Pacific islander; admissions; emergency department presentations; gout
0.585
85
Internal Medicine
Medicine
2,023
35,669,909
Identification of KRBA1 as a Potential Prognostic Biomarker Associated with Immune Infiltration and m6A Modification in Hepatocellular Carcinoma.
Journal of hepatocellular carcinoma
J Hepatocell Carcinoma
9
null
10.2147/JHC.S363862
eng
2,022
null
null
2,022
5
31
[PURPOSE] Hepatocellular carcinoma (HCC) is a malignancy with high incidence, but its prognosis is not optimistic. KRBA1 is a member of the KRAB family and participates in the regulation of gene transcription. However, no studies have focused on the role of KRBA1 in HCC. [PATIENTS AND METHODS] In this study, we first a...
KRBA1; biomarker; hepatocellular carcinoma; immune infiltration; m6A modification; prognosis
null
10
Hepatology; Oncology
Medicine
2,023
35,669,696
Outcomes of 2111 COVID-19 Hospitalized Patients Treated with Hydroxychloroquine/Azithromycin and Other Regimens in Marseille, France, 2020: A Monocentric Retrospective Analysis.
Therapeutics and clinical risk management
Ther Clin Risk Manag
18
null
10.2147/TCRM.S364022
eng
2,022
null
null
2,022
5
31
[OBJECTIVES] We evaluated the 6-week mortality of SARS-CoV-2 hospitalized patients treated using a standardized protocol in 2020 in Marseille, France. [METHODS] A retrospective monocentric cohort study was conducted in the standard hospital wards at the Institut Hospitalo-Universitaire Méditerranée Infection, between M...
COVID-19; SARS-CoV-2; azithromycin; hydroxychloroquine
0.652
74
Pharmacology, Toxicology and Pharmaceutics; Safety Research; Chemical Health and Safety; Medicine; Pharmacology
Chemical Engineering; Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
2,022
35,669,468
Lipoprotein(a) and Cardiovascular Outcomes in Patients With Coronary Artery Disease and Different Metabolic Phenotypes.
Frontiers in cardiovascular medicine
Front Cardiovasc Med
9
null
10.3389/fcvm.2022.870341
eng
2,022
null
null
2,022
5
20
[BACKGROUND] The positive relationship between metabolic healthy obesity (MHO) and cardiovascular risk has been under debate in recent years. Previously, strong evidence supported the causal role of increased plasma lipoprotein(a) [Lp(a)] levels in cardiovascular disease (CVD). The current study aimed to investigate th...
CAD; coronary severity; lipoprotein(a); metabolic phenotypes; outcome
1.391
81
Cardiology and Cardiovascular Medicine
Medicine
2,022
35,668,888
Financial Barriers in Emerging Adults With Type 1 Diabetes: A Qualitative Analysis.
Diabetes spectrum : a publication of the American Diabetes Association
Diabetes Spectr
35
2
10.2337/ds21-0038
eng
2,022
null
null
2,022
1
18
[BACKGROUND] Emerging adulthood is a period fraught with challenging life transitions for many and is especially difficult for individuals with type 1 diabetes, as they encounter more obstacles to independently managing their diabetes. We examined the barriers faced by emerging adults and parents of emerging adults wit...
null
0.555
47
Internal Medicine; Endocrinology, Diabetes and Metabolism
Medicine
2,022
35,668,782
Integrating Network Pharmacology and In Vivo Model to Investigate the Mechanism of Biheimaer in the Treatment of Functional Dyspepsia.
Evidence-based complementary and alternative medicine : eCAM
Evid Based Complement Alternat Med
2022
null
10.1155/2022/8773527
eng
2,022
null
null
2,022
5
27
[OBJECTIVE] Biheimaer (BHM) is a hospital formulation for clinical treatment of dyspepsia and acid reflux, based on Compatibility Theory of Traditional Chinese Medicine. This study anticipated to elucidate the molecular mechanism of BHM against Functional dyspepsia via combined network pharmacology prediction with expe...
null
null
null
null
null
null
35,668,737
Volumetric Analysis of the Jaws in Skeletal Class I and III Patients with Different Facial Divergence Using CBCT Imaging.
Radiology research and practice
Radiol Res Pract
2022
null
10.1155/2022/2416555
eng
2,022
null
null
2,022
5
28
[AIM] The main objective was to evaluate any possible maxillary or mandibular volumetric difference between hyperdivergent skeletal Class III (CIII), normodivergent skeletal CIII, hypodivergent skeletal CIII, and normodivergent skeletal Class I (CI) patients using cone-beam computed tomography (CBCT) images. Also, the ...
null
null
null
null
null
null
35,668,633
Lipid variability and risk of microvascular complications in Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial: A post hoc analysis.
Journal of diabetes
J Diabetes
14
6
10.1111/1753-0407.13273
eng
2,022
6
null
2,022
6
6
[BACKGROUND] Greater lipid variability may cause adverse health events among diabetic patients. We aimed to examine the effect of lipid variability on the risk of diabetic microvascular outcomes among type 2 diabetes mellitus patients. [METHODS] We assessed the association between visit-to-visit variability (measured b...
high-density lipoprotein; low-density lipoprotein; microvascular complications; remnant cholesterol; triglyceride
1.028
61
Endocrinology, Diabetes and Metabolism
Medicine
2,022
35,668,510
Factors affecting retention of veterinary practitioners in Ireland: a cross-sectional study with a focus on clinical practice.
Irish veterinary journal
Ir Vet J
75
1
10.1186/s13620-022-00222-9
eng
2,022
6
7
2,022
6
7
[BACKGROUND] Retention of veterinary practitioners has arisen as a significant problem in recent years in Ireland. No prior Irish peer-reviewed publications have addressed this problem. An online questionnaire was available through social media and via email to Irish vets from January to November 2019. The aim of this ...
Gender equality; Recruitment; Retention; Salary; Sustainability; Veterinary employees; Work-life balance
null
null
null
null
null
35,668,436
The changes in the nursing practice environment brought by COVID-19 and improvement recommendations from the nurses' perspective: a cross-sectional study.
BMC health services research
BMC Health Serv Res
22
1
10.1186/s12913-022-08135-7
eng
2,022
6
6
2,022
6
6
[BACKGROUND] The COVID-19 pandemic has brought an opportunity to increase investment in the nursing practice environment, which has greatly impacted patients, nurses, and organizations. However, there were limited studies concerning the changes in the practice environment since the COVID-19 pandemic and the way to impr...
COVID-19; Nurse; Organization and administration; Practice environment; Working condition
0.964
157
Health Policy
Medicine
2,022
35,668,411
Diagnostic accuracy of interferon-gamma release assays for diagnosis of smear-negative pulmonary tuberculosis: a systematic review and meta-analysis.
BMC pulmonary medicine
BMC Pulm Med
22
1
10.1186/s12890-022-02013-y
eng
2,022
6
6
2,022
6
6
[INTRODUCTION] The diagnosis of smear-negative pulmonary tuberculosis (SNPTB) is challenging. Interferon gamma-release assays (IGRAs) may be helpful in early diagnosis among these patients resulting in prompt treatment and favorable outcomes. [METHODS] We performed a comprehensive search from each databases' inception ...
Diagnosis; Interferon-gamma release assays; Meta-analysis; Sensitivity; Smear-negative; Specificity; Tuberculosis
0.999
85
Pulmonary and Respiratory Medicine
Medicine
2,022
35,668,377
Parents' satisfaction of tele-rehabilitation for children with neurodevelopmental disabilities during the COVID-19 pandemic.
BMC primary care
BMC Prim Care
23
1
10.1186/s12875-022-01747-2
eng
2,022
6
7
2,022
6
7
[BACKGROUND] The use of tele-rehabilitation in children was limited before the COVID-19 pandemic, due to culture, technology access, regulatory and reimbursement barriers. [METHODS] The study was conducted according to the CHERRIES (Checklist for reporting results of internet E-surveys) guidelines in order to provide q...
COVID-19; Neurodevelopmental disabilities; Tele-rehabilitation
0.981
95
Family Practice; Medicine
Medicine
2,022
35,667,886
Investigation of the process intergrowth of bone tissue into the hole in titanium implants (Experimental research).
Injury
Injury
53
8
10.1016/j.injury.2022.05.007
eng
2,022
8
null
2,022
5
19
[INTRODUCTION] Despite the use of modern implants, complications such as nonunion and avascular necrosis of the femoral head are observed in femoral neck fractures (FNF). We have created a new perforated I-beam implant for FNF osteosynthesis and developed a new osteosynthesis philosophy based not only on the mechanical...
Experiment; Femoral neck fracture; Histological studies; New perforated implant; Regeneration of bone tissue
0.698
151
Surgery; Emergency Medicine; Orthopedics and Sports Medicine
Medicine
2,022
35,667,729
Value-based healthcare in Latin America: a survey of 70 healthcare provider organisations from Argentina, Brazil, Chile, Colombia and Mexico.
BMJ open
BMJ Open
12
6
10.1136/bmjopen-2021-058198
eng
2,022
6
6
2,022
6
6
[OBJECTIVES] Value-based healthcare (VBHC) is a health system reform gradually being implemented in health systems worldwide. A previous national-level survey has shown that Latin American countries were in the early stages of alignment with VBHC. Data at the healthcare provider organisations (HPOs) level are lacking. ...
international health services; organisation of health services; qualitative research
1.059
176
Medicine
Medicine
2,022
35,667,380
Mass Switch From Intravenous to Subcutaneous Tocilizumab in Rheumatic Diseases During the SARS-COV-2 Pandemic.
Journal of clinical rheumatology : practical reports on rheumatic musculoskeletal diseases
J Clin Rheumatol
28
7
10.1097/RHU.0000000000001862
eng
2,022
10
1
2,022
6
8
[BACKGROUND] With the arrival of the SARS-CoV-2 pandemic in 2020, it was proposed to make the change from intravenous (IV) tocilizumab (TCZ) to its subcutaneous formulation, in order to avoid rheumatological patients having to go to the day hospital and guarantee enough IV TCZ for those critical patients with COVID who...
null
0.616
63
Medicine; Rheumatology
Medicine
2,022
35,667,296
Preoperative prediction of overt hepatic encephalopathy caused by transjugular intrahepatic portosystemic shunt.
European journal of radiology
Eur J Radiol
154
null
10.1016/j.ejrad.2022.110384
eng
2,022
9
null
2,022
5
28
[PURPOSE] Preoperative prediction of overt hepatic encephalopathy (OHE) should be performed in patients with variceal bleeding treated using the transjugular intrahepatic portosystemic shunt (TIPS) procedure. A reliable prediction tool is therefore required. [METHOD] Patients with cirrhosis-related variceal bleeding tr...
Clinical factors; Overt hepatic encephalopathy; Preoperative prediction; Radiological characteristics; Transjugular intrahepatic portosystemic shunt
0.939
139
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,667,226
Pulmonary rehabilitation in subterranean chambers combined with neuro-orthopedic activity-dependent plasticity therapy influences patients' quality of life - A preliminary study.
Complementary therapies in clinical practice
Complement Ther Clin Pract
48
null
10.1016/j.ctcp.2022.101609
eng
2,022
8
null
2,022
5
27
[OBJECTIVE] The aim of the study was to evaluate if Neuro-orthopedic Activity-dependent Plasticity (N.A.P.) therapy combined with standard subterranean pulmonary rehabilitation (SPR) conducted in the salt mine influences the health-related quality of life (HRQoL) and chest mobility in patients with asthma or chronic up...
15D instrument; Back scratch; Chest mobility; Exercise therapy; Speleotherapy; Vagus nerve
0.664
67
Complementary and Alternative Medicine
Medicine
2,022
35,667,164
Collaborative Integration of Palliative Care in Critically Ill Stroke Patients in the Neurocritical Care Unit: A Single Center Pilot Study.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
31
8
10.1016/j.jstrokecerebrovasdis.2022.106586
eng
2,022
8
null
2,022
6
3
[INTRODUCTION] Patients admitted to the Neurocritical Care Unit (NCCU) with moderate-to-severe acute strokes, along with their surrogate decision makers, have the potential for unrecognized or unmet emotional and psychological needs. Our primary objective was to determine if early integration of palliative care consult...
Acute stroke; Cerebrovascular accident; Intensive care unit; Palliative care; Palliative medicine
0.713
85
Rehabilitation; Surgery; Cardiology and Cardiovascular Medicine; Neurology
Medicine
2,022
35,666,753
Vitamin D-mediated effects on airway innate immunity in vitro.
PloS one
PLoS One
17
6
10.1371/journal.pone.0269647
eng
2,022
null
null
2,022
6
6
[INTRODUCTION] Vitamin D supplementation has been suggested to enhance immunity during respiratory infection season. We tested the effect of active vitamin D (calcitriol) supplementation on key airway innate immune mechanisms in vitro. [METHODS] Primary human airway epithelial cells (hAECs) grown at the air liquid inte...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
35,666,750
Screening for untreated atrial fibrillation in the elderly population: A community-based study.
PloS one
PLoS One
17
6
10.1371/journal.pone.0269506
eng
2,022
null
null
2,022
6
6
[BACKGROUND] Strokes are common in people with atrial fibrillation (AF), and can have devastating consequences, especially in the elderly and if AF is untreated. However, community-based studies on screening for untreated AF have not been conducted in Japan, and there has been no evaluation of the effectiveness of earl...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
35,666,742
Prediction of blood pressure changes associated with abdominal pressure changes during robotic laparoscopic low abdominal surgery using deep learning.
PloS one
PLoS One
17
6
10.1371/journal.pone.0269468
eng
2,022
null
null
2,022
6
6
[BACKGROUND] Intraoperative hypertension and blood pressure (BP) fluctuation are known to be associated with negative patient outcomes. During robotic lower abdominal surgery, the patient's abdominal cavity is filled with CO2, and the patient's head is steeply positioned toward the floor (Trendelenburg position). Pneum...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
35,666,610
Circulating microRNAs (miR-16, miR-22, miR-122) expression and early diagnosis of hepatocellular carcinoma.
Journal of clinical laboratory analysis
J Clin Lab Anal
36
7
10.1002/jcla.24541
eng
2,022
7
null
2,022
6
6
[PURPOSE] Circulating microRNA (miRNA) has been reported to have diagnostic value in multiple tumors. To identify serum miRNAs for early diagnosis of hepatocellular carcinoma (HCC), we analyzed the differential miRNA expression between HCC patients and controls. [METHODS] Real-time reverse transcription polymerase chai...
early diagnosis; hepatocellular carcinoma; microRNA-122; microRNA-16; target genes
0.594
67
Medical Laboratory Technology; Biochemistry; Clinical Biochemistry; Public Health, Environmental and Occupational Health; Hematology; Immunology and Allergy; Microbiology
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine
2,022
35,666,456
Effect of early feeding practices and eating behaviors on body composition in primary school children.
World journal of pediatrics : WJP
World J Pediatr
18
9
10.1007/s12519-022-00559-9
eng
2,022
9
null
2,022
6
6
[BACKGROUND] Understanding children's feeding practices and eating behaviors is important to determine etiology of childhood obesity. This study aimed to explore the relationship between early feeding practices, eating behavior and body composition among primary school children. [METHODS] The data were collected from 4...
Blood pressure; Child eating behaviors; Childhood obesity; Feeding practices; Waist circumference
0.838
51
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,666,249
David Against Goliath: Direct Comparison of Handheld Bowel Sonography and Magnetic Resonance Enterography for Diagnosis of Crohn's Disease.
Inflammatory bowel diseases
Inflamm Bowel Dis
29
4
10.1093/ibd/izac116
eng
2,023
4
3
null
null
null
[BACKGROUND] Diagnosis of Crohn's disease (CD) requires ileo-colonoscopy (IC) and cross-sectional evaluation. Recently, "echoscopy" has been used effectively in several settings, although data about its use for CD diagnosis are still limited. Our aim was to evaluate the diagnostic accuracy of handheld bowel sonography ...
IBD; echoscopy; handheld bowel sonography; magnetic resonance enterography; pocket size ultrasound
1.55
183
Gastroenterology; Immunology and Allergy
Medicine
2,023
35,665,534
Evidence for origin of lavender foal syndrome among Egyptian Arabian horses in Egypt.
Equine veterinary journal
Equine Vet J
55
3
10.1111/evj.13604
eng
2,023
5
null
2,022
7
12
[BACKGROUND] Lavender foal syndrome (LFS) is a fatal hereditary condition that is inherited in an autosomal recessive pattern. This detrimental mutation is more common in Arabian foals of Egyptian origin than foals from other bloodlines. Heterozygous horses are carriers of the LFS trait and appear normal, while recessi...
LFS; MYO5A; deletion; horse; nervous signs
0.812
105
Equine
Veterinary
2,023
35,665,533
Electromyographic analysis of pelvic floor muscles during the execution of pelvic patterns of proprioceptive neuromuscular facilitation-concept: An observational study.
Neurourology and urodynamics
Neurourol Urodyn
41
6
10.1002/nau.24981
eng
2,022
8
null
2,022
6
5
[OBJECTIVE] To assess the effect of pelvic patterns of proprioceptive neuromuscular facilitation (PNF-concept) on pelvic floor muscles (PFM) recruitment, as well as the electromyographic activity of muscles synergic to the pelvic floor in healthy women. [METHODS] Observational study conducted with 31 women aged between...
abdominal muscles; electromyography; motor control; muscle stretching exercises; physiotherapy modalities; proprioceptive neuromuscular facilitation
0.721
112
Urology; Neurology
Medicine
2,022
35,665,354
Parents' Perceptions and Intention to Vaccinate Their Children Against COVID-19: Results From a Cross-Sectional National Survey in India.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.806702
eng
2,022
null
null
2,022
5
18
[BACKGROUND] Despite the success of adult vaccination against COVID-19, providing vaccines to children remains a challenge for policymakers globally. As parents are primary decision-makers for their children, we aimed to assess parents' perceptions and intentions regarding COVID-19 vaccination in India. [METHODS] A cro...
children; risk perception; trust; vaccine acceptance; vaccine hesitancy
0.926
102
Medicine
Medicine
2,022
35,665,038
The Vasodilatory Response to CGRP of the Anterior and Posterior Cerebral Circulation in Migraine.
Frontiers in neurology
Front Neurol
13
null
10.3389/fneur.2022.854134
eng
2,022
null
null
2,022
5
19
[INTRODUCTION] Migraine aura can be associated with headache or it may occur without one, which suggests an independent mechanism for the aura and for migraine headache. The role of CGRP in migraine headache is well established, but the connection between CGRP and the aura is still lacking an explanation. Exogenous CGR...
CGRP; aura; headache; migraine; vasodilatory response
0.978
118
Neurology; Neurology
Medicine; Neuroscience
2,022
35,664,488
Depressive, Anxiety Symptom Frequency and Related Factors Among Prisoners During the COVID-19 Pandemic in Northeastern Ethiopia, a Cross-Sectional Study.
Frontiers in psychiatry
Front Psychiatry
13
null
10.3389/fpsyt.2022.820015
eng
2,022
null
null
2,022
5
17
[BACKGROUND] Among the more than 10 million people imprisoned around the world, the rate of mental illness is higher than among the general population for various reasons. Although rates of mental illnesses such as depression and anxiety in this population may have changed as a response to the coronavirus disease (COVI...
Ethiopia; anxiety; depression; factors; prisoner
1.222
134
Psychiatry and Mental Health
Medicine
2,022
35,664,343
Machine Learning Classifiers to Evaluate Data From Gait Analysis With Depth Cameras in Patients With Parkinson's Disease.
Frontiers in human neuroscience
Front Hum Neurosci
16
null
10.3389/fnhum.2022.826376
eng
2,022
null
null
2,022
5
19
[INTRODUCTION] The assessments of the motor symptoms in Parkinson's disease (PD) are usually limited to clinical rating scales (MDS UPDRS III), and it depends on the clinician's experience. This study aims to propose a machine learning technique algorithm using the variables from upper and lower limbs, to classify peop...
biomechanics; depth camera; gait; kinect; machine learning
0.787
168
Behavioral Neuroscience; Neurology; Neuropsychology and Physiological Psychology; Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience; Psychology
2,022
35,663,378
Growth hormone therapy in HHRH.
Bone reports
Bone Rep
16
null
10.1016/j.bonr.2022.101591
eng
2,022
6
null
2,022
5
18
[BACKGROUND] Hereditary Hypophosphatemic Rickets with Hypercalciuria (HHRH) (SLC34A3 gene, OMIM 241530) is an autosomal recessive disorder that results in a loss of function of the sodium-phosphate NPT2c channel at the proximal tubule. Phosphate supplementation rarely improves serum phosphate, hypercalciuria, nephrocal...
23Na MRI; Recombinant human growth hormone; Sodium phosphate cotransporter; Tubular phosphate wasting
0.56
35
Orthopedics and Sports Medicine; Endocrinology, Diabetes and Metabolism
Medicine
2,022
35,663,322
A Clinicopathological and Molecular Analysis of Sellar/Suprasellar Neurocytoma Mimicking Pituitary Adenoma.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
13
null
10.3389/fendo.2022.861540
eng
2,022
null
null
2,022
5
18
[OBJECTIVE] To investigate the clinicopathological characteristics, molecular genetic characteristics and prognosis of extraventricular neurocytoma located in the sellar/suprasellar region. [METHODS] Seven archived tumor samples derived from 4 patients with neurocytoma in the sellar/suprasellar region were collected fr...
clincopathology; extraventricular neurocytoma; neurocytoma; pituitary tumor; sellar and suprasellar region
1.278
138
Endocrinology, Diabetes and Metabolism
Medicine
2,022
35,663,129
Players at home: Physical activity and quality of life in 12-17 years-old football (soccer) players during the Covid-19 lockdown.
International journal of sports science coaching
Int J Sports Sci Coach
17
3
10.1177/17479541211041703
eng
2,022
6
null
null
null
null
[BACKGROUND] Aggressive preventive actions were required to face the Covid-19 outbreak. However, from March 2020 on, many healthy youth football players have seen their sporting activities disrupted by the restrictions on outdoor exercise.This study describes physical activity and quality of life during April 2020 lock...
Adolescence; health; pandemic; youth sport
null
null
null
null
null
35,663,077
Distribution and changes in hepatitis C virus genotype in China from 2010 to 2020.
World journal of clinical cases
World J Clin Cases
10
14
10.12998/wjcc.v10.i14.4480
eng
2,022
5
16
null
null
null
[BACKGROUND] Hepatitis C virus (HCV) causes a large number of infections worldwide. New infections seem to be increasing according to a report of the World Health Organization in 2015. Although direct-acting antivirals are quite effective for most genotypes of the HCV, some genotypes fail to respond. Therefore, the tre...
China; Direct-acting antiviral; Drug users; Genotype; Hepacivirus; Hepatitis C virus
null
38
Medicine
Medicine
2,022
35,662,818
Virtual-Augmented Reality and Life-Like Neurosurgical Simulator for Training: First Evaluation of a Hands-On Experience for Residents.
Frontiers in surgery
Front Surg
9
null
10.3389/fsurg.2022.862948
eng
2,022
null
null
2,022
5
19
[BACKGROUND] In the recent years, growing interest in simulation-based surgical education has led to various practical alternatives for medical training. More recently, courses based on virtual reality (VR) and three-dimensional (3D)-printed models are available. In this paper, a hybrid (virtual and physical) neurosurg...
brain; life-like actuation; neurosurgery; residents; simulator; training; virtual reality
0.459
48
Surgery
Medicine
2,022
35,662,675
Early and mid-term outcomes of transcatheter tricuspid valve repair: systematic review and meta-analysis of observational studies.
Revista espanola de cardiologia (English ed.)
Rev Esp Cardiol (Engl Ed)
76
5
10.1016/j.rec.2022.06.004
eng
2,023
5
null
2,022
6
2
[INTRODUCTION AND OBJECTIVES] Severe tricuspid regurgitation (TR) is associated with poor prognosis when left untreated, and a growing number of studies on transcatheter tricuspid valve repair (TTVr) have been published over the last few months. [METHODS] We performed a comprehensive systematic review of published lite...
Transcatheter tricuspid valve intervention; Transcatheter tricuspid valve repair; Tricuspid incompetence; Tricuspid regurgitation; tricuspid valve insufficiency
0.593
80
Cardiology and Cardiovascular Medicine
Medicine
2,023
35,662,573
Multi-modality connectome-based predictive modeling of individualized compulsions in obsessive-compulsive disorder.
Journal of affective disorders
J Affect Disord
311
null
10.1016/j.jad.2022.05.120
eng
2,022
8
15
2,022
5
31
[BACKGROUND] While previous neuroimaging studies are mainly focused on dichotomous classification of obsessive-compulsive disorder (OCD) from controls, predicting continuous severity of specific symptom is also pivotal to clinical diagnosis and treatment. [METHODS] We applied a machine-learning approach, connectome-bas...
Compulsions; Connectome-based predictive modeling (CPM); DTI; Obsessive-compulsive disorder (OCD); Resting-state fMRI
1.988
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
35,662,352
A low-energy-dense dietary pattern: a narrative review.
Nutrition reviews
Nutr Rev
80
12
10.1093/nutrit/nuac037
eng
2,022
11
7
null
null
null
[BACKGROUND] Dietary recommendations have promoted the consumption of a low-energy-dense dietary pattern; however, guidelines to implement this dietary pattern are lacking. [OBJECTIVES] The objectives of this narrative review are to discuss approaches used to implement a low-energy-dense dietary pattern within dietary ...
dietary intervention; dietary patterns; energy density
1.521
185
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
35,662,291
Cardiovascular risk of gonadotropin-releasing hormone antagonist versus agonist in men with prostate cancer: an observational study in Taiwan.
Prostate cancer and prostatic diseases
Prostate Cancer Prostatic Dis
26
4
10.1038/s41391-022-00555-0
eng
2,023
12
null
2,022
6
3
[BACKGROUND] The impact of gonadotropin-releasing hormone (GnRH) antagonist and agonist (GnRHa) treatment on cardiovascular disease (CVD) risk in prostate cancer (PCa) remains inconclusive due to conflicting findings. We compared the effects of GnRH antagonist and GnRHa treatments on CVD risk in patients with PCa and p...
null
1.711
81
Cancer Research; Oncology; Urology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
35,662,251
The effect of tracheostomy on extracorporeal membrane oxygenation outcomes.
Journal of cardiac surgery
J Card Surg
37
9
10.1111/jocs.16666
eng
2,022
9
null
2,022
6
6
[INTRODUCTION] The optimal timing for pursuing tracheostomy in patients with prolonged mechanical ventilation with either veno-arterial (VA) or veno-venous (VV) extracorporeal membrane oxygenation (ECMO) is a discussion of risk versus benefit. Depending on the etiology, cardiothoracic surgical patients carry some of th...
cardiovascular research; clinical review
0.445
69
Surgery; Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022
35,662,146
Asthma Smarts Education: Increased Disease Knowledge and Reduced School Nurse Visits.
Progress in community health partnerships : research, education, and action
Prog Community Health Partnersh
16
2
10.1353/cpr.2022.0023
eng
2,022
null
null
null
null
null
[BACKGROUND] Worldwide, asthma is one of the most prevalent chronic diseases. Lack of asthma knowledge can lead to exacerbations, emergency room visits, absenteeism, and decreased quality of life. Asthma prevalence in Milwaukee Public Schools (MPS) is often 20% or higher, and among children ages 5 to 17, asthma is a le...
null
null
null
null
null
null
35,661,578
Exploring the microaggression experiences of LGBTQ+ community for a culturally safe care: A descriptive qualitative study.
Nurse education today
Nurse Educ Today
115
null
10.1016/j.nedt.2022.105423
eng
2,022
8
null
2,022
6
1
[BACKGROUND] Microaggressions, stigma and minority stress still occur among sexual and gender minorities on an individual, interpersonal, and structural level. Cultural immersion may therefore be an effective strategy in order to find potential healthcare approaches and foster more comprehensive, critical, intersection...
Culturally safe care; Microaggressions; Nursing; Qualitative research; Sexual and gender minorities
0.946
109
Education; Nursing
Nursing; Social Sciences
2,022
35,661,490
Mental health gaps characteristics in the management of schizophrenia in a developing upper middle-income South-East Asian country.
Asian journal of psychiatry
Asian J Psychiatr
74
null
10.1016/j.ajp.2022.103170
eng
2,022
8
null
2,022
5
16
[OBJECTIVE] The Mental Health Gap Action Program (mhGAP) was launched by the World Health Organization (WHO) in 2008 to address the lack of care of people in low and middle-income countries The purpose of this narrative review is to examine Mental Health Gaps in the management of Schizophrenia in Malaysia. [METHOD] A s...
Malaysia; Mental health gap action program; Mental health policy; Mental health system; Recovery-oriented practices
1.326
70
Medicine; Psychiatry and Mental Health; Psychology
Medicine; Psychology
2,022
35,661,483
Helicobacter bilis infection induces oxidative stress in and enhances the proliferation of human cholangiocytes.
Helicobacter
Helicobacter
27
4
10.1111/hel.12908
eng
2,022
8
null
2,022
6
6
[BACKGROUND] Helicobacter bilis, an enterohepatic Helicobacter species, represents a carcinogenic risk factor for cholangiocytes owing to the prevalence of infections in patients with biliary tract cancer, cholecystitis, and pancreaticobiliary maljunction. However, the effect of H. bilis infection on cholangiocytes and...
Helicobacter bilis; biliary tract; cholangiocarcinoma; chronic inflammation; reactive oxidant species
1.29
94
Gastroenterology; Infectious Diseases; Medicine
Medicine
2,022
35,661,117
Adverse Drug Reactions of Intranasal Corticosteroids in the Netherlands: An Analysis from the Netherlands Pharmacovigilance Center.
Drugs - real world outcomes
Drugs Real World Outcomes
9
3
10.1007/s40801-022-00301-x
eng
2,022
9
null
2,022
6
3
[BACKGROUND] Intranasal corticosteroids are one of the cornerstone treatment options for allergic rhinitis and chronic sinusitis complaints. Safety information in the summary of product characteristics may not be representative for observations in daily clinical practice. The Netherlands Pharmacovigilance Center (Lareb...
null
0.564
24
Pharmacology
Medicine
2,022
35,660,916
Ultrasonographic measurement of abdominal and gluteal-femoral fat thickness as a predictor for android/gynoid ratio.
European journal of radiology
Eur J Radiol
154
null
10.1016/j.ejrad.2022.110387
eng
2,022
9
null
2,022
5
31
[OBJECTIVE] To evaluate the use of ultrasonography (US) as an alternative to dual-energy x-ray absorptiometry (DXA) to predict the percentage ratio of android/gynoid (A/G) fat mass. [METHODS] This was a cross-sectional study. Twenty-eight participants included in the study underwent whole-body DXA examinations and the ...
Adipose tissue; Android fat; Body fat distribution; Dual-energy x-ray absorptiometry; Gynoid fat; Ultrasonography
0.939
139
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
35,660,855
Association of Sociodemographic Factors With Reported Penicillin Allergy in Pediatric Inpatients.
Hospital pediatrics
Hosp Pediatr
12
7
10.1542/hpeds.2021-006462
eng
2,022
7
1
null
null
null
[OBJECTIVES] Characterize the association of sociodemographic factors with reported penicillin allergy in pediatric inpatients. [METHODS] We conducted a retrospective cohort study of pediatric inpatients admitted to general pediatric units at an academic medical center with reported penicillin allergy and reaction hist...
null
0.908
41
Medicine; Pediatrics; Pediatrics, Perinatology and Child Health
Medicine; Nursing
2,022
35,660,670
Percutaneous Transforaminal Endoscopic Debridement and Drainage with Accurate Pathogen Detection for Infectious Spondylitis of the Thoracolumbar and Lumbar Spine.
World neurosurgery
World Neurosurg
164
null
10.1016/j.wneu.2022.05.123
eng
2,022
8
null
2,022
6
2
[OBJECTIVE] In this study, we aimed to analyze the clinical outcomes of percutaneous transforaminal endoscopic debridement and drainage (PTEDD) with accurate pathogen detection for patients with infectious spondylitis of the thoracolumbar and lumbar spines. [METHODS] From January 2017 to February 2019, a consecutive se...
Infectious spondylitis; Next-generation sequencing; Thoracolumbar and lumbar spine
0.591
123
Neurology; Surgery
Medicine
2,022
35,660,536
Mechanical-based therapies may reduce pain and disability in some patients with knee osteoarthritis: A systematic review with meta-analysis.
The Knee
Knee
37
null
10.1016/j.knee.2022.05.005
eng
2,022
8
null
2,022
6
3
[BACKGROUND] Mechanical-based therapies are not yet recommended to manage osteoarthritis (OA). This systematic review and meta-analysis aim to assess the effects of passive mechanical-based therapies (isolated or combined with other therapies) on patients with knee OA compared to placebo, other isolated or combined int...
Extracorporeal shockwave therapy; Knee osteoarthritis; Passive mechanical stimulation; Phonophoresis; Therapeutic ultrasound; Vibration
0.782
98
Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,022