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35,974,934
Hypophosphatemia after hemodialysis and its association with some clinical complications in patients with chronic kidney disease.
Caspian journal of internal medicine
Caspian J Intern Med
13
3
10.22088/cjim.13.3.527
eng
2,022
null
null
null
null
null
[BACKGROUND] Beyond the adverse effects of hyperphosphatemia in patients with chronic kidney disease (CKD(, hypophosphatemia has also been proposed as a common challenge after dialysis. Therefore, the present study aimed to evaluate the serum phosphate level immediately after hemodialysis (HD) and its association with ...
null
null
null
null
null
null
35,974,335
PredictiveNetwork: predictive gene network estimation with application to gastric cancer drug response-predictive network analysis.
BMC bioinformatics
BMC Bioinformatics
23
1
10.1186/s12859-022-04871-z
eng
2,022
8
16
2,022
8
16
[BACKGROUND] Gene regulatory networks have garnered a large amount of attention to understand disease mechanisms caused by complex molecular network interactions. These networks have been applied to predict specific clinical characteristics, e.g., cancer, pathogenicity, and anti-cancer drug sensitivity. However, in mos...
Aldo-keto reductase family; Anti-cancer drug sensitivity; Gastric cancer; Gene network
1.1
251
Applied Mathematics; Biochemistry; Computer Science Applications; Molecular Biology; Structural Biology
Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics
2,022
35,974,208
Clinical characteristics, AR gene variants, and functional domains in 64 patients with androgen insensitivity syndrome.
Journal of endocrinological investigation
J Endocrinol Invest
46
1
10.1007/s40618-022-01894-4
eng
2,023
1
null
2,022
8
16
[BACKGROUND] Androgen insensitivity syndrome (AIS) is caused by abnormal androgen receptor (AR) genes that show variable genotypes and phenotypes. However, the correlation between genotype and phenotype is unclear. [METHODS] We retrospectively evaluated 64 patients with AIS at Shanghai Children's Hospital from 2015 to ...
Androgen insensitivity syndrome (AIS); Androgen receptor; Functional domain; Variant
1.067
104
Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
35,973,643
The effect of trait self-control on dyspnoea and tolerance to a CO2 rebreathing challenge in healthy males and females.
Physiology behavior
Physiol Behav
255
null
10.1016/j.physbeh.2022.113944
eng
2,022
10
15
2,022
8
13
[BACKGROUND] High trait self-control is associated with greater tolerance of unpleasant sensations including effort and pain. Dyspnoea and pain have several commonalities and this study aimed to investigate for the first time whether trait self-control influences responses to a hypercapnic rebreathing challenge designe...
Air hunger; CO(2) rebreathing; Dyspnoea; Multi-dimensional dyspnoea profile; Self-control; Tolerance
null
null
null
null
null
35,973,445
Pursuing a Career in Pediatrics: Intersection of Educational Debt and Race/Ethnicity.
The Journal of pediatrics
J Pediatr
252
null
10.1016/j.jpeds.2022.08.014
eng
2,023
1
null
2,022
8
13
[OBJECTIVES] To examine the associations among pediatric trainees' self-reported race/ethnicity, educational debt, and other factors for pursuing a pediatrics career. [STUDY DESIGN] Cross-sectional study using data from the American Board of Pediatrics In-training Examination Post-examination Survey years 2018-2020 of ...
educational debt; pediatrics; race/ethnicity
1.043
246
Pediatrics, Perinatology and Child Health
Medicine
2,023
35,973,315
Culture-based determinants and outcome of Staphylococcus aureus bloodstream infections.
Diagnostic microbiology and infectious disease
Diagn Microbiol Infect Dis
104
3
10.1016/j.diagmicrobio.2022.115772
eng
2,022
11
null
2,022
7
22
[BACKGROUND] The objective of this study was to examine the occurrence, determinants, and outcome of S. aureus bloodstream infections (BSI) diagnosed based on single versus multiple positive initial cultures. [METHODS] All adults with first episodes of mono-microbial S. aureus BSI in Queensland during 2000-2019 were in...
Bacteremia, Incidence; Bloodstream infection; Epidemiology; Staphylococcus aureus
null
null
null
null
null
35,973,263
Cardiovascular safety associated with febuxostat versus allopurinol among patients with gout: Update with accumulated use of febuxostat.
Seminars in arthritis and rheumatism
Semin Arthritis Rheum
56
null
10.1016/j.semarthrit.2022.152080
eng
2,022
10
null
2,022
8
3
[BACKGROUND] To re-evaluate comparative cardiovascular (CV) safety of febuxostat versus allopurinol among patients with gout following recent accumulated use of febuxostat. [METHODS] Using 2011-2019 Korea National Health Insurance database, we conducted a cohort study comparing gout patients initiating febuxostat versu...
Allopurinol; Cardiovascular safety; Febuxostat; Gout
1.594
139
Anesthesiology and Pain Medicine; Rheumatology
Medicine
2,022
35,973,209
Racial Fairness in Precision Medicine: Pediatric Asthma Prediction Algorithms.
American journal of health promotion : AJHP
Am J Health Promot
37
2
10.1177/08901171221121639
eng
2,023
2
null
2,022
8
16
[PURPOSE] Quantify and examine the racial fairness of two widely used childhood asthma predictive precision medicine algorithms: the asthma predictive index (API) and the pediatric asthma risk score (PARS). [DESIGN] Apply the API and PARS and evaluate model performance overall and when stratified by race. [SETTING] Cin...
asthma; fairness; pediatric; precision medicine; racial minority
0.882
103
Health; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,023
35,972,939
Factors Associated With Fertility Preservation in a Pediatric, Adolescent and Young Adult Population.
Journal of pediatric hematology/oncology
J Pediatr Hematol Oncol
44
7
10.1097/MPH.0000000000002515
eng
2,022
10
1
2,022
8
9
[OBJECTIVE] To determine the patient characteristics associated with pursuing fertility preservation (FP) before gonadotoxic therapy in a pediatric, adolescent and young adult patient population. [METHODS] This is a retrospective cohort study of patient data at Cincinnati Children's Hospital Medical Center. Demographic...
null
0.368
88
Hematology; Oncology; Pediatrics, Perinatology and Child Health
Medicine
2,022
35,972,749
Including measures of chronic kidney disease to improve cardiovascular risk prediction by SCORE2 and SCORE2-OP.
European journal of preventive cardiology
Eur J Prev Cardiol
30
1
10.1093/eurjpc/zwac176
eng
2,023
1
11
null
null
null
[AIMS] The 2021 European Society of Cardiology (ESC) guideline on cardiovascular disease (CVD) prevention categorizes moderate and severe chronic kidney disease (CKD) as high and very-high CVD risk status regardless of other factors like age and does not include estimated glomerular filtration rate (eGFR) and albuminur...
Cardiovascular disease; Chronic kidney disease; Meta-analysis; Risk prediction
1.866
130
Cardiology and Cardiovascular Medicine; Epidemiology
Medicine
2,023
35,972,583
Impact of Medicaid Expansion on Incidence and Mortality from Gastric and Esophageal Cancer.
Digestive diseases and sciences
Dig Dis Sci
68
4
10.1007/s10620-022-07659-6
eng
2,023
4
null
2,022
8
16
[BACKGROUND AND AIMS] Individuals in Medicaid expanded states have increased access to treatment for medical conditions and other health care resources. Esophageal and gastric cancer are associated with several modifiable risk factors (e.g. smoking, drinking, Helicobacter pylori infection). The impact of Medicaid expan...
Esophageal cancer; Gastric cancer; Incidence; Medicaid expansion; Mortality
1.068
146
Gastroenterology; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
35,972,141
Diagnosis and management of bile leaks after severe liver injury: A Trauma Association of Canada multicenter study.
The journal of trauma and acute care surgery
J Trauma Acute Care Surg
93
6
10.1097/TA.0000000000003765
eng
2,022
12
1
2,022
8
16
[BACKGROUND] Optimal management of bile leaks (BLs) after severe liver injury is unknown. Study objectives were to define current practices in diagnosis and management of BL to determine which patients may benefit from endoscopic retrograde cholangiopancreatography (ERCP). [METHODS] American Association for the Surgery...
null
1.11
217
Critical Care and Intensive Care Medicine; Surgery
Medicine
2,022
35,971,866
European Neuromuscular Centre consensus statement on anaesthesia in patients with neuromuscular disorders.
European journal of neurology
Eur J Neurol
29
12
10.1111/ene.15526
eng
2,022
12
null
2,022
9
14
[BACKGROUND AND PURPOSE] Patients with neuromuscular conditions are at increased risk of suffering perioperative complications related to anaesthesia. There is currently little specific anaesthetic guidance concerning these patients. Here, we present the European Neuromuscular Centre (ENMC) consensus statement on anaes...
anaesthesia; malignant hyperthermia; myopathy; neuromuscular disorders; perioperative care
1.554
151
Neurology; Neurology
Medicine; Neuroscience
2,022
35,971,279
Effect of cryotherapy on paclitaxel-induced peripheral neuropathy of the hand in female breast cancer patients: A prospective self-controlled study.
International journal of nursing practice
Int J Nurs Pract
29
4
10.1111/ijn.13094
eng
2,023
8
null
2,022
8
15
[AIMS] The purpose of this study was to examine the efficacy of cryotherapy with frozen gloves for the prevention of the chemotherapy-induced peripheral neuropathy of the hand. [BACKGROUND] Most breast cancer patients receive chemotherapy; consequently, patients frequently experience adverse effects of chemotherapy-ind...
breast cancer; cryotherapy; frozen gloves; nursing; peripheral neuropathy
0.734
66
Nursing
Nursing
2,023
35,971,274
The marital relationship and health-related quality of life of prostate cancer patients and their spouses: A prospective, longitudinal study.
International journal of nursing practice
Int J Nurs Pract
28
6
10.1111/ijn.13093
eng
2,022
12
null
2,022
8
15
[AIMS] This study aims to measure any changes in the marital relationship during the first year after a diagnosis of prostate cancer, identify the demographic characteristics that influenced such changes, and measure changes related to health-related quality of life (HRQoL). [BACKGROUND] Knowledge is limited on the imp...
health-related quality of life; longitudinal study; marital relationship; prostate cancer patients; spouses
0.614
66
Nursing
Nursing
2,022
35,971,171
Immunostimulatory effects of Nannochloropsis oculata supplementation on Barki rams growth performance, antioxidant assay, and immunological status.
BMC veterinary research
BMC Vet Res
18
1
10.1186/s12917-022-03417-y
eng
2,022
8
15
2,022
8
15
[BACKGROUND] Natural feed supplements are gaining popularity in the animal production sector due to their safety and potential immunostimulatory properties, as well as the ban of some antibiotics and their negative residual effects. This study was carried out for 1 month to investigate the effect of Nannochloropsis ocu...
null
0.668
86
Veterinary; Medicine
Medicine; Veterinary
2,022
35,971,120
Validation of Responsiveness of Physicians Scale (ROP-Scale) for hospitalised COVID-19 patients in Bangladesh.
BMC health services research
BMC Health Serv Res
22
1
10.1186/s12913-022-08413-4
eng
2,022
8
15
2,022
8
15
[BACKGROUND] Responsiveness of Physicians (ROP) is defined as the social actions by physicians aimed at meeting the legitimate expectations of healthcare users. Even though patients' expectations regarding ROP have increased during the COVID-19 pandemic, the psychometrically-validated ROP-Scale is difficult to apply in...
Bangladesh; Patient satisfaction; Psychometric evaluation; Responsiveness of physicians; Scale validation
0.964
157
Health Policy
Medicine
2,022
35,971,116
Lineage tracing shows that cell size asymmetries predict the dorsoventral axis in the sea star embryo.
BMC biology
BMC Biol
20
1
10.1186/s12915-022-01359-3
eng
2,022
8
15
2,022
8
15
[BACKGROUND] Cell size asymmetries are often linked to cell fate decisions, due to cell volumes and cell fate determinants being unequally partitioned during asymmetric cell divisions. A clear example is found in the sea urchin embryo, where a characteristic and obvious unequal 4th cleavage generates micromeres, which ...
Cell fate; Cell size; Dorsoventral axis; Echinoderm; Embryo patterning
null
null
null
null
null
35,971,084
Transcriptomic analysis reveals the regulatory role of quorum sensing in the Acinetobacter baumannii ATCC 19606 via RNA-seq.
BMC microbiology
BMC Microbiol
22
1
10.1186/s12866-022-02612-z
eng
2,022
8
16
2,022
8
16
[BACKGROUND] Acinetobacter baumannii has emerged as the major opportunistic pathogen in healthcare-associated infections with high-level antibiotic resistance and high mortality. Quorum sensing (QS) system is a cell-to-cell bacterial communication mediated by the synthesis, secretion, and binding of auto-inducer signal...
Acinetobacter baumannii; Quorum sensing; RNA-seq; Regulatory mechanism; Transcriptomic analysis; Virulence
0.937
147
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,022
35,970,709
Physical and Mental Health Problems and Their Associations With Inter-Personal Sexual Inactivity and Sexual Dysfunctions in Denmark: Baseline Assessment in a National Cohort Study.
The journal of sexual medicine
J Sex Med
19
10
10.1016/j.jsxm.2022.07.004
eng
2,022
10
null
2,022
8
13
[BACKGROUND] Physical and mental health are important to sexual function and wellbeing. Yet, associations of ill-health with sexual inactivity and dysfunctions are scarcely researched at population level. [AIM] To explore and document associations of self-rated health and physical and mental health problems with inter-...
Chronic Diseases; Denmark; Epidemiology; Mental Health; Sexual Dysfunctions; Sexual Health
0.947
145
Obstetrics and Gynecology; Reproductive Medicine; Urology; Endocrinology; Endocrinology, Diabetes and Metabolism; Psychiatry and Mental Health
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,970,635
Epidemiology and outcomes of older trauma patients in Singapore: A multicentre study.
Injury
Injury
53
10
10.1016/j.injury.2022.08.018
eng
2,022
10
null
2,022
8
8
[BACKGROUND] An ageing population has caused rising trauma cases amongst older patients. Multiple comorbidities, polypharmacy and limited reserves predispose them to poorer outcomes following a traumatic event. The Comorbidity Polypharmacy Score (CPS) has been found to predict outcomes and mortality in older trauma pat...
Geriatric trauma; Polypharmacy; Trauma severity indices
0.698
151
Surgery; Emergency Medicine; Orthopedics and Sports Medicine
Medicine
2,022
35,970,396
Prehospital care for traumatic cardiac arrest in the US: A cross-sectional analysis and call for a national guideline.
Resuscitation
Resuscitation
179
null
10.1016/j.resuscitation.2022.08.005
eng
2,022
10
null
2,022
8
12
[AIM] We describe emergency medical services (EMS) protocols and prehospital practice patterns related to traumatic cardiac arrest (TCA) management in the U.S. [METHODS] We examined EMS management of TCA by 1) assessing variability in recommended treatments in state EMS protocols for TCA and 2) analyzing EMS care using...
Emergency medical services; Prehospital; Resuscitation; Termination of resuscitation; Traumatic cardiac arrest
2.242
162
Cardiology and Cardiovascular Medicine; Emergency Medicine; Emergency Nursing
Medicine; Nursing
2,022
35,970,318
A Deep Learning Model for Automated Segmentation of Geographic Atrophy Imaged Using Swept-Source OCT.
Ophthalmology. Retina
Ophthalmol Retina
7
2
10.1016/j.oret.2022.08.007
eng
2,023
2
null
2,022
8
12
[PURPOSE] To present a deep learning algorithm for segmentation of geographic atrophy (GA) using en face swept-source OCT (SS-OCT) images that is accurate and reproducible for the assessment of GA growth over time. [DESIGN] Retrospective review of images obtained as part of a prospective natural history study. [SUBJECT...
Automated algorithm; Deep learning; Geographic atrophy; SS-OCT; Swept-source OCT
1.963
53
Ophthalmology
Medicine
2,023
35,969,115
Video-assisted thoracic surgery in critically ill COVID-19 patients on venovenous extracorporeal membrane oxygenation.
Perfusion
Perfusion
38
8
10.1177/02676591221119319
eng
2,023
11
null
2,022
8
15
[INTRODUCTION] Coronavirus disease 2019 (COVID-19) leads to thoracic complications requiring surgery. This is challenging, particularly in patients supported with venovenous extracorporeal membrane oxygenation (VV-ECMO) due to the need for continuous therapeutic anticoagulation. We aim to share our experience regarding...
COVID-19; Video-assisted thoracic surgery; hemostasis; thoracoscopy; venovenous extracorporeal membrane oxygenation
0.433
55
Advanced and Specialized Nursing; Safety Research; Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging
Medicine; Nursing; Social Sciences
2,023
35,969,010
MiR-192-5p/RB1/NF-κBp65 signaling axis promotes IL-10 secretion during gastric cancer EMT to induce Treg cell differentiation in the tumour microenvironment.
Clinical and translational medicine
Clin Transl Med
12
8
10.1002/ctm2.992
eng
2,022
8
null
null
null
null
[BACKGROUND] Regulatory T (Treg) cells are important components of the tumour microenvironment (TME) that play roles in gastric cancer (GC) metastasis. Although tumour cells that undergo epithelial-mesenchymal transition (EMT) regulate Treg cell function, their regulatory mechanism in GC remains unclear. [METHODS] The ...
EMT; IL-10; RB1; Tregs; gastric cancer; miR-192-5p
1.706
24
Medicine; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,968,996
Early Knee Range of Motion Following Operative Treatment for Tibial Tubercle Avulsion Fractures Is Safe.
Journal of pediatric orthopedics
J Pediatr Orthop
42
9
10.1097/BPO.0000000000002237
eng
2,022
10
1
2,022
8
15
[BACKGROUND] Tibial tubercle avulsion fractures (TTAF) often require surgical reduction and stabilization. Traditional teachings recommend postoperative knee immobilization for 4 to 6 weeks; however, the necessity of these restrictions is unclear and the actual practice varies. This study's purpose was to: (1) retrospe...
null
null
null
null
null
null
35,968,802
An overview of three-dimensional imaging devices in dentistry.
Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]
J Esthet Restor Dent
34
8
10.1111/jerd.12955
eng
2,022
12
null
2,022
8
15
[OBJECTIVE] To review four types of three-dimensional imaging devices: intraoral scanners, extraoral scanners, cone-beam computed tomography (CBCT), and facial scanners, in terms of their development, technologies, advantages, disadvantages, accuracy, influencing factors, and applications in dentistry. [METHODS] PubMed...
3D imaging; CBCT; extraoral scanner; facial scanner; intraoral scanner; scanning
0.996
79
Dentistry
Dentistry
2,022
35,968,397
Continuous positive airway pressure therapy suppresses inflammatory cytokines and improves glucocorticoid responsiveness in patients with obstructive sleep apnea and asthma: A case-control study.
Annals of thoracic medicine
Ann Thorac Med
17
3
10.4103/atm.atm_37_22
eng
2,022
null
null
2,022
7
9
[CONTEXT] Asthma and obstructive sleep apnea (OSA) are prevalent respiratory disorders that frequently coexist. Continuous positive airway pressure (CPAP) therapy is the standard treatment for OSA. However, its effects on systemic inflammation and glucocorticoid responsiveness in OSA patients with asthma are largely un...
Asthma; continuous positive airway pressure (CPAP); cytokines; glucocorticoids; inflammation; inflammatory biomarkers; obstructive sleep apnea; systemic
0.476
47
Surgery; Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022
35,968,061
Foodborne zoonotic trematode infections in Yen Bai, Vietnam: a situational analysis on knowledge, attitude, and practice (KAP) and risk behaviors.
Journal of preventive medicine and hygiene
J Prev Med Hyg
63
2
10.15167/2421-4248/jpmh2022.63.2.2104
eng
2,022
6
null
2,022
7
31
[INTRODUCTION] Foodborne Zoonotic Trematode Infections (FZTi) are neglected tropical diseases of public health concern in Vietnam. The transmission of FZTi is linked to human behavior patterns. The aims to investigate the knowledge, attitude, and practices regarding FZTi among local people. [METHODS] A cross-sectional ...
Foodborne Zoonotic Trematode Infections; Intestinal flukes; KAP; Liver flukes; Vietnam
0.405
40
Infectious Diseases; Public Health, Environmental and Occupational Health
Medicine
2,022
35,967,960
Mesenteric Vascular Evaluation with Pre-operative Multidetector Computed Tomographic Angiography and Intraoperative Indocyanine Green Angiography to Reduce Anastomotic Leaks after Minimally Invasive Surgery for Colorectal Cancer.
JSLS : Journal of the Society of Laparoendoscopic Surgeons
JSLS
26
3
10.4293/JSLS.2022.00022
eng
2,022
null
null
null
null
null
[BACKGROUND] The aim of this prospective study was to determine the effect of mesenteric vascular evaluation using pre-operative multidetector computed tomography angiography (MDCTA) and intraoperative indocyanine green (ICG) angiography on reducing the anastomotic leak rate of colorectal cancer patients undergoing min...
Anastomotic leak; Colorectal cancer; Colorectal surgery; Computed tomography angiography; Fluorescein angiography; Minimally invasive surgical procedures
null
null
null
null
null
35,967,917
Progranulin Promotes the Formation and Development of Capsules Caused by Silicone in Sprague-Dawley Rats.
Clinical, cosmetic and investigational dermatology
Clin Cosmet Investig Dermatol
15
null
10.2147/CCID.S374128
eng
2,022
null
null
2,022
8
6
[BACKGROUND] Silicone implants are currently the most widely used artificial materials in plastic surgery. Capsule formation following implant application is unavoidable. When the capsule is excessively thick and strongly contracted, it can lead to obvious symptoms, clinically known as capsular contracture. Biological ...
fibroblast; fibrosis; implantation; silicone implants
0.624
59
Dermatology
Medicine
2,022
35,967,585
Novel NHEJ1 pathogenic variant linked to severe combined immunodeficiency, microcephaly, and abnormal T and B cell receptor repertoires.
Frontiers in pediatrics
Front Pediatr
10
null
10.3389/fped.2022.883173
eng
2,022
null
null
2,022
7
27
[BACKGROUND] During the process of generating diverse T and B cell receptor (TCR and BCR, respectively) repertoires, double-strand DNA breaks are produced. Subsequently, these breaks are corrected by a complex system led by the non-homologous end-joining (NHEJ). Pathogenic variants in genes involved in this process, su...
NHEJ1; TCR repertoire; XLF/Cernunnos; next-generation sequencing (NGS); severe combined immunodeficiency (SCID)
0.798
83
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,967,580
An outbreak of infection due to severe acute respiratory corona virus-2 in a neonatal unit from a low and middle income setting.
Frontiers in pediatrics
Front Pediatr
10
null
10.3389/fped.2022.933982
eng
2,022
null
null
2,022
7
28
[INTRODUCTION] The provision of kangaroo mother care (KMC) involving continuous skin-to-skin care (SSC) is an important intervention in neonatal care, which is recommended even when women are infected with severe acute respiratory syndrome coronavirus (SARS-CoV-2). We report on a nosocomial outbreak of SARS-CoV-2 infec...
SARS-CoV-2; langaroo mother care (KMC); neonate; non-pharmaceutical interventions (NPI); outbreak
0.798
83
Pediatrics, Perinatology and Child Health
Medicine
2,022
35,967,397
Serum concentration of extracellular cold-inducible RNA-binding protein is associated with respiratory failure in COVID-19.
Frontiers in immunology
Front Immunol
13
null
10.3389/fimmu.2022.945603
eng
2,022
null
null
2,022
7
29
[UNLABELLED] Uncontrolled release of damage-associated molecular patterns (DAMPs) is suggested to be a major trigger for the dysregulated host immune response that leads to severe COVID-19. Cold-inducible RNA-binding protein (CIRP), is a newly identified DAMP that aggravates inflammation and tissue injury, and induces ...
CIRP; COVID-19; DAMPs; eCIRP; inflammation; severity
2.022
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
35,967,307
A Systematic Review and Meta-Analysis of 19 Randomized Controlled Trials of Iguratimod Combined With Other Therapies for Sjogren's Syndrome.
Frontiers in immunology
Front Immunol
13
null
10.3389/fimmu.2022.924730
eng
2,022
null
null
2,022
7
28
[OBJECTIVE] To explore the efficacy and safety of Iguratimod intervention in Primary Sjogren's syndrome (pSS). [METHODS] Many databases were searched to collect the RCTs. Three independent reviewers extracted data and assessed the quality of the studies based on the Cochrane Handbook. The statistical analysis was done ...
iguratimod; meta-analysis; randomized controlled trials; systematic review
2.022
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
35,966,882
Severity of depressive but not anxiety symptoms impacts glucose metabolism among patients with type 2 diabetes in primary care.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.944047
eng
2,022
null
null
2,022
7
28
[BACKGROUND] Data from primary care regarding the prevalence of symptoms of depression and anxiety, and their effect on glycemic control among people with diabetes is lacking in Hungary. The recently introduced Patient Health Record (PHR) requires family doctors to screen for depressive symptoms. [OBJECTIVES] We aimed ...
anxiety; depression; mental health; primary care; screening; type 2 diabetes
0.926
102
Medicine
Medicine
2,022
35,966,613
Role of T Lymphocyte Activation Profile in Predicting SARS-CoV-2 Severity: Experience from Tertiary Care Centre of North India.
Indian journal of hematology blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion
Indian J Hematol Blood Transfus
39
1
10.1007/s12288-022-01558-6
eng
2,023
1
null
2,022
8
9
[BACKGROUND] Immune dysregulation plays a key role in determining COVID-19 disease severity. We aimed to analyze the T cell activation profile in COVID - 19 cases and its predictive role in disease severity and outcome. [MATERIAL AND METHODS] This was a prospective observational pilot study from a tertiary care COVID-1...
COVID-19; Disease severity; Outcome; Severity; T cell Activation profile; T lymphocyte activation
null
null
null
null
null
36,033,492
Positive surgical margins may not affect the survival of patients with renal cell carcinoma after partial nephrectomy: A meta-analysis based on 39 studies.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.945166
eng
2,022
null
null
2,022
8
10
[BACKGROUND] So far, whether positive surgical margin(PSM) has adverse effects on the prognosis of patients is still controversial, so we designed this study to systematically evaluate the effect of PSM on the prognosis of patients with renal cell carcinoma (RCC) after partial nephrectomy (PN). [METHODS] On the basis o...
partial nephrectomy; positive surgical margin; prognosis; renal cell carcinoma; survival
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,033,473
Effective dissecting range and prognostic significance of lateral pelvic lymph node dissection for middle-low rectal cancer patients with lateral pelvic lymph node metastasis: Results of a large multicenter lateral node collaborative group in China.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.916285
eng
2,022
null
null
2,022
8
12
[BACKGROUND] Lateral pelvic lymph node (LPN) metastasis causes increased lateral local recurrence and poor prognosis. We aimed to investigate the prognostic significance and effective range of dissection for the LPN dissection (LPND) in rectal cancer patients with LPN metastasis. [MATERIALS AND METHODS] Through this la...
lateral pelvic lymph node; lateral pelvic lymph node metastasis; prognosis; rectal cancer; surgical dissection
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,033,351
Adversity and child body mass index in Fragile Families over 15 years: Do type and timing matter?
SSM - population health
SSM Popul Health
19
null
10.1016/j.ssmph.2022.101197
eng
2,022
9
null
2,022
8
13
[BACKGROUND] Weight status has been linked to adverse childhood experiences. Existing research, however, is limited to unidimensional assessments of cumulative risk and does not account for the complex nature of adversity experienced by children in high-risk settings. We fill existing gaps by assessing how four subtype...
Adverse childhood experiences; Childhood obesity prevention; Community violence; Economic hardship; Fragile families; Interpersonal violence
1.785
64
Health Policy; Health; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,022
36,033,290
Post-transport TOPS score as a predictive marker of mortality among transported neonates and its comparative analysis with SNAP-II PE.
Heliyon
Heliyon
8
8
10.1016/j.heliyon.2022.e10165
eng
2,022
8
null
2,022
8
9
[AIM] Multiple parameters are available to predict the outcome of critically sick neonates admitted in neonatal intensive care unit (NICU). Main aim of the study is to validate the role of TOPS, especially the post-transport TOPS score as a simplified assessment of neonatal acute physiology in predicting mortality amon...
Critically ill; Mortality; Neonates; SNAP II PE; TOPS score
0.609
115
Multidisciplinary
Multidisciplinary
2,022
36,033,199
Patients With Generalized Joint Hypermobility Have Thinner Superior Hip Capsules and Greater Hip Internal Rotation on Physical Examination.
Arthroscopy, sports medicine, and rehabilitation
Arthrosc Sports Med Rehabil
4
4
10.1016/j.asmr.2022.04.031
eng
2,022
8
null
2,022
7
5
[PURPOSE] To compare preoperative hip range of motion (ROM), hip capsular thickness on magnetic resonance imaging (MRI), and bony morphology on radiographs and computed tomography (CT) between patients with and without joint hypermobility as measured by the Beighton Test score (BTS), with subanalysis based on sex and a...
null
0.632
21
Rehabilitation; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Public Health, Environmental and Occupational Health
Health Professions; Medicine
2,022
36,033,008
Impact of closure of educational institutions due to COVID-19 lockdown on overall subjective wellbeing of adolescents and youth: Cross-sectional survey, India.
Frontiers in psychology
Front Psychol
13
null
10.3389/fpsyg.2022.903044
eng
2,022
null
null
2,022
8
12
[BACKGROUND] Students were confined to their homes due to the national closure of educational institutions during the COVID 19 pandemic, thus presenting an unprecedented risk to children's education, protection, and wellbeing. [AIM] This study aimed to understand the determinants of subjective wellbeing of adolescents ...
COVID-19; India; adolescent; educational institution; subjective wellbeing
0.891
212
Psychology
Psychology
2,022
36,032,937
The Neuroprotective Propensity of Organic Extracts of Acacia stenophylla Bark and Their Effectiveness Against Scopolamine-/Diazepam-Induced Amnesia in Mice.
Journal of inflammation research
J Inflamm Res
15
null
10.2147/JIR.S376242
eng
2,022
null
null
2,022
8
22
[BACKGROUND] Alzheimer's disease (AD) is a neurodegenerative disorder that is more prevalent in the elderly. There is extensive literature on using Acacia species against central nervous system disorders, although Acacia stenophylla has not been investigated for any neuroprotective potential. The purpose of the study w...
Acacia stenophylla; acetylcholinesterase; amnesia; cognitive deficits; oxidative stress
0.889
58
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
36,032,318
Analysis of Range and Use of a Hybrid Hydrogen Peroxide System for Biosafety Level 3 and Animal Biosafety Level 3 Agriculture Laboratory Decontamination.
Applied biosafety : journal of the American Biological Safety Association
Appl Biosaf
27
1
10.1089/apb.2021.0012
eng
2,022
3
1
2,022
3
15
[INTRODUCTION] The applications of fumigation and the challenges that high-containment facilities face in achieving effective large volume decontamination are well understood. The Biosecurity Research Institute at Kansas State University sought to evaluate a novel system within their biosafety level 3 (BSL-3) and anima...
decontamination; fogging; high level disinfectant; hydrogen peroxide vapor; sterilant
0.309
15
Biotechnology; Management, Monitoring, Policy and Law; Public Health, Environmental and Occupational Health; Health, Toxicology and Mutagenesis
Biochemistry, Genetics and Molecular Biology; Environmental Science; Medicine
2,022
36,031,862
Water and nutrient availability exert selection on reproductive phenology.
American journal of botany
Am J Bot
109
11
10.1002/ajb2.16057
eng
2,022
11
null
2,022
11
3
[PREMISE] Global change has changed resource availability to plants, which could shift the adaptive landscape. We hypothesize that novel water and nutrient availability combinations alter patterns of natural selection on reproductive phenology in Boechera stricta (Brassicaceae) and influence the evolution of local adap...
Brassicaceae; G matrix; flowering time; genotypic selection; local adaptation; resource availability
0.863
178
Ecology, Evolution, Behavior and Systematics; Plant Science; Genetics
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
2,022
36,031,546
The feasibility of academic detailing for acute oral pain management in outpatient dentistry: A pilot study.
Journal of the American Pharmacists Association : JAPhA
J Am Pharm Assoc (2003)
63
1
10.1016/j.japh.2022.08.001
eng
2,023
null
null
2,022
8
5
[BACKGROUND] Opioids are overprescribed in the outpatient dental setting. Therefore, opportunities exist for opioid stewardship. [OBJECTIVES] The purpose of this pilot study was to test the feasibility of an academic detailing (AD) intervention to promote appropriate prescribing of opioids in outpatient dentistry. [MET...
null
0.593
75
Pharmacology; Pharmacy; Pharmacology
Health Professions; Nursing; Pharmacology, Toxicology and Pharmaceutics
2,023
36,031,441
Brain Structure in Acutely Underweight and Partially Weight-Restored Individuals With Anorexia Nervosa: A Coordinated Analysis by the ENIGMA Eating Disorders Working Group.
Biological psychiatry
Biol Psychiatry
92
9
10.1016/j.biopsych.2022.04.022
eng
2,022
11
1
2,022
5
31
[BACKGROUND] The pattern of structural brain abnormalities in anorexia nervosa (AN) is still not well understood. While several studies report substantial deficits in gray matter volume and cortical thickness in acutely underweight patients, others find no differences, or even increases in patients compared with health...
BMI; Cortical thickness; MRI; Subcortical volume; Surface area
3.768
367
Biological Psychiatry
Neuroscience
2,022
36,031,270
Convergent validity of vision based technology (VBT) among professional bus drivers.
Journal of safety research
J Safety Res
82
null
10.1016/j.jsr.2022.07.007
eng
2,022
9
null
2,022
7
22
[INTRODUCTION] Due to the relative rarity of crashes, researchers use traffic offenses, police records, public complaints, and In-Vehicle Data Recorder (IVDR) data as proxies for assessing crash risk. In this study, a unique IVDR system, called Vision-Based Technology [(VBT), (Mobileye Inc.)] was used to monitor perilo...
Binary-logistic regression model; Crash involvement; In vehicle data recorder; Naturalistic driving; Professional drivers
1.109
110
Safety, Risk, Reliability and Quality
Engineering
2,022
36,031,263
Prioritization of industry level interventions to improve implementation of design for safety regulations.
Journal of safety research
J Safety Res
82
null
10.1016/j.jsr.2022.06.011
eng
2,022
9
null
2,022
6
27
[INTRODUCTION] Many countries introduced mandatory Design for Safety (DfS) or Prevention through Design (PtD) requirements to reduce construction accident rates. However, there is a knowledge gap on the relative importance of industry level interventions to improve the implementation of DfS regulations. Thus, this stud...
Building design; Construction safety; Industry-level interventions; Safety interventions
1.109
110
Safety, Risk, Reliability and Quality
Engineering
2,022
36,030,673
The impact of electroconductive multifunctional composite nanofibrous scaffold on adipose-derived mesenchymal stem cells.
Tissue cell
Tissue Cell
78
null
10.1016/j.tice.2022.101899
eng
2,022
10
null
2,022
8
20
[BACKGROUND] The development of tissue-engineered scaffolds with electrical properties is the primary motivation of novel regenerative medicine. Electroconductive scaffolds are designed to mimic the injured tissue environment's electrical properties and regulate cellular behavior - growth, proliferation, and differenti...
Electrical stimulation; Mesenchymal stem cell; NGF; Neural cell differentiation; Scaffold
null
null
null
null
null
36,030,448
A Surgeon-Volume Comparison of Opioid Prescribing Patterns to Adolescents Following Outpatient Shoulder, Hip, and Knee Arthroscopy.
Bulletin of the Hospital for Joint Disease (2013)
Bull Hosp Jt Dis (2013)
80
3
null
eng
2,022
9
null
null
null
null
[PURPOSE] Given the wide variation that exists in the amount and duration of postoperative opioid medication prescribed by orthopedic surgeons, the purpose of the current study was to analyze the opioid prescribing patterns at our institution for adolescent patients undergoing outpatient sports medicine procedures Meth...
null
null
null
null
null
null
36,030,429
The influence of prior dental pathology on medical complications and peri-prosthetic joint infections following primary shoulder arthroplasty.
European journal of orthopaedic surgery traumatology : orthopedie traumatologie
Eur J Orthop Surg Traumatol
33
5
10.1007/s00590-022-03378-w
eng
2,023
7
null
2,022
8
28
[PURPOSE] Antibiotic prophylaxis before invasive dental procedures is a common practice in the USA. Consensus regarding the influence of prior dental pathology (DP) on postoperative complications is lacking. The objectives are to determine the association of DP prior to shoulder arthroplasty (SA) on: (1) lengths of sta...
Complications; Database; Dental work; Infection; Oral hygiene; Outcomes; Peri-prosthetic joint infections; Shoulder arthroplasty
null
null
null
null
null
36,030,313
Long-term outcomes after using retrievable vena cava filters in major trauma patients with contraindications to prophylactic anticoagulation.
European journal of trauma and emergency surgery : official publication of the European Trauma Society
Eur J Trauma Emerg Surg
49
1
10.1007/s00068-022-02074-y
eng
2,023
2
null
2,022
8
27
[PURPOSE] To investigate the long-term outcomes of using vena cava filters to prevent symptomatic pulmonary embolism (PE) in major trauma patients who have contraindications to prophylactic anticoagulation. [METHODS] This was an a priori sub-study of a randomized controlled trial (RCT) involving long-term outcome data ...
Complications; Costs; Prevention; Vena cava filters; Venous thromboembolism
0.661
54
Critical Care and Intensive Care Medicine; Emergency Medicine; Orthopedics and Sports Medicine; Surgery
Medicine
2,023
36,029,956
A pre-operative radiological score to predict lymph node metastasis in advanced epithelial ovarian cancer.
Journal of gynecology obstetrics and human reproduction
J Gynecol Obstet Hum Reprod
51
9
10.1016/j.jogoh.2022.102464
eng
2,022
11
null
2,022
8
24
[BACKGROUND] Lymphadenectomy is part of cytoreductive surgery for patients with advanced epithelial ovarian cancer (AEOC) in case of abnormal lymph nodes before and during surgery. The aim of this study was to develop and validate a pre-operative radiological score to predict pelvic and/or para-aortic lymph node metast...
Advanced epithelial ovarian cancer; CT; Lymph node metastasis; Lymphadenectomy; PET/CT; Pre-operative score
0.529
47
Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,022
36,029,368
Results From Drug-Drug Interaction Studies In Vitro and In Vivo Investigating the Inhibitory Effect of Finerenone on the Drug Transporters BCRP, OATP1B1, and OATP1B3.
European journal of drug metabolism and pharmacokinetics
Eur J Drug Metab Pharmacokinet
47
6
10.1007/s13318-022-00794-5
eng
2,022
11
null
2,022
8
27
[BACKGROUND AND OBJECTIVES] In vitro and in vivo studies were performed with the novel, selective, nonsteroidal mineralocorticoid receptor antagonist finerenone to assess the relevance of inhibitory effects on the transporters breast cancer resistance protein (BCRP), organic anion transporting polypeptide 1B1 (OATP1B1)...
null
0.524
50
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,029,344
Inter-observer variability of expert-derived morphologic risk predictors in aortic dissection.
European radiology
Eur Radiol
33
2
10.1007/s00330-022-09056-z
eng
2,023
2
null
2,022
8
27
[OBJECTIVES] Establishing the reproducibility of expert-derived measurements on CTA exams of aortic dissection is clinically important and paramount for ground-truth determination for machine learning. [METHODS] Four independent observers retrospectively evaluated CTA exams of 72 patients with uncomplicated Stanford ty...
Aortic dissection; Computed tomography angiography; Variability, inter-observer
1.656
182
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,023
36,029,300
Medical genetics education for pediatrics residents: A brief report.
Genetics in medicine : official journal of the American College of Medical Genetics
Genet Med
24
11
10.1016/j.gim.2022.08.003
eng
2,022
11
null
2,022
8
27
[PURPOSE] Genetic testing is ubiquitous in the field of medicine and is often ordered or requested by primary care providers, nongenetics subspecialists, and patients themselves. Other studies have shown that providers are often not comfortable ordering genetic testing. There have been initiatives to teach these concep...
Genetics Training; MedEd; Medical Genetics Education; Medical Genetics Residency; Pediatrics Residency
2.745
167
Genetics; Medicine
Medicine
2,022
36,029,024
Significance of Glucose Control for Perioperative and Long-Term Renal Functions after Nephron-sparing Surgery for Renal Cancer in Patients with Diabetes.
Urology journal
Urol J
20
2
10.22037/uj.v19i.7103
eng
2,023
2
27
2,023
2
27
[PURPOSE] This study aimed to evaluate the predictive factors for perioperative and long-term renal functions after nephron-sparing surgery (NSS). [MATERIALS AND METHODS] The clinical records of 379 patients who underwent NSS for a single renal tumor with a normal contralateral kidney between 2009 and 2016 were retrosp...
null
0.383
38
Urology
Medicine
2,023
36,028,842
SHFLD3 phenotypes caused by 17p13.3 triplication/ duplication encompassing Fingerin (BHLHA9) invariably.
Orphanet journal of rare diseases
Orphanet J Rare Dis
17
1
10.1186/s13023-022-02480-w
eng
2,022
8
26
2,022
8
26
[BACKGROUND] Split-hand/ foot malformation with long bone deficiency 3 (SHFLD3) is an extremely rare condition associated with duplications located on 17p13.3, which invariably encompasses the BHLHA9 gene. The disease inherits with variable expressivity and significant incomplete penetrance as high as 50%. [RESULTS] We...
Array CGH; CNV; Duplication; Ectrodactyly; Long bone deficiency; Monodactyly; SHFM; Tibia aplasia; Triplication
1.12
143
Medicine; Pharmacology; Genetics
Medicine
2,022
36,028,381
Nationwide analysis of proximity of American College of Surgeons-verified and state-designated trauma centers to the nearest highway exit and associated prehospital motor vehicle collision fatalities.
Surgery
Surgery
172
5
10.1016/j.surg.2022.07.011
eng
2,022
11
null
2,022
8
24
[BACKGROUND] Motor vehicle collisions remain a leading cause of trauma-related deaths. We aim to investigate the relationship between the proximity of trauma centers to the nearest highway exit and prehospital motor vehicle collision fatalities at the county level nationwide. [METHODS] This was a cross-sectional study ...
null
null
null
null
null
null
36,028,111
Minimally Invasive Resection of Intraventricular Pilocytic Astrocytoma Using the Aurora Surgiscope in an Adult Patient: Technical Note.
World neurosurgery
World Neurosurg
168
null
10.1016/j.wneu.2022.08.071
eng
2,022
12
null
2,022
8
24
[BACKGROUND] Pilocytic astrocytomas account for approximately 5%-6% of all gliomas and are most commonly diagnosed between the ages of 8 and 13 years. Although they may occur throughout the neuraxis, approximately two thirds arise from the cerebellum and optic pathway. Other locations of origin include midline structur...
Aurora Surgiscope; Bimanual surgery; Endoscopic; Minimally invasive; Sulcal dissection; Tumor resection
0.591
123
Neurology; Surgery
Medicine
2,022
36,028,047
Amphetamine, methamphetamine, and MDMA in hair samples from a rehabilitation facility: Validation and applicability of HF-LPME-GC-MS.
Journal of pharmacological and toxicological methods
J Pharmacol Toxicol Methods
119
null
10.1016/j.vascn.2022.107212
eng
2,023
null
null
2,022
8
24
[INTRODUCTION] It is known that drug abuse jeopardizes economic and social development. Toxicological analyses can guide prevention and treatment strategies in rehabilitation facilities. The current greatest challenge is finding easily adaptable and less costly sensitive methods that meet the principles of green chemis...
Amphetamines; Analytical validation; Chromatography-Mass Spectrometry; Hair samples; Hollow Fiber Liquid-phase Microextraction; Methods; Rehabilitation facility
null
null
null
null
null
36,027,852
GDF-15 and sST-2 act as biomarkers of disease severity but not independent predictors in idiopathic membranous nephropathy.
International immunopharmacology
Int Immunopharmacol
111
null
10.1016/j.intimp.2022.109150
eng
2,022
10
null
2,022
8
24
[BACKGROUND] We aimed to explore biomarkers of disease severity in idiopathic membranous nephropathy (IMN) and independent predictors of prognosis in IMN. [METHODS] Clinical data were collected from 79 IMN patients. Serum levels of growth differentiation factor-15 (GDF-15) and soluble suppression of tumorigenicity (sST...
Combined-factors model; Growth differentiation factor-15; Idiopathic membranous nephropathy; Prognosis; Soluble suppression of tumorigenicity
1.1
155
Pharmacology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,027,830
Menetrier's disease in a morbid obese patient undergoing bariatric surgery: A case report.
International journal of surgery case reports
Int J Surg Case Rep
98
null
10.1016/j.ijscr.2022.107539
eng
2,022
9
null
2,022
8
23
[INTRODUCTION AND IMPORTANCE] Menetrier's disease is a rare type of hypertrophic gastropathy characterized by the atrophy of the gastric parietal cells and dilatation of mucus releasing glands. Hereby, we present a morbid obese patient who has undergone laparoscopic sleeve gastrectomy (LSG) and he has also diagnosed wi...
Bariatric surgery; Menetrier's disease; Morbid obesity; Preoperative endoscopy; Sleeve gastrectomy
0.193
31
Surgery
Medicine
2,022
36,026,545
Masquelet Technique for the Tibia: A Systematic Review and Meta-Analysis of Contemporary Outcomes.
Journal of orthopaedic trauma
J Orthop Trauma
37
1
10.1097/BOT.0000000000002480
eng
2,023
1
1
null
null
null
[OBJECTIVE] To systematically review outcomes of the Masquelet "induced membrane" technique (MT) in treatment of tibial segmental bone loss and to assess the impact of defect size on union rate when using this procedure. [DATA SOURCES] PubMed, EBSCO, Cochrane, and SCOPUS were searched for English language studies from ...
null
0.965
150
Medicine; Orthopedics and Sports Medicine; Surgery; Sports Science
Health Professions; Medicine
2,023
36,018,890
Associations of symptom combinations with in-hospital mortality of coronavirus disease-2019 patients using South Korean National data.
PloS one
PLoS One
17
8
10.1371/journal.pone.0273654
eng
2,022
null
null
2,022
8
26
[BACKGROUND] There are various risk factors for death in coronavirus disease-2019 (COVID-19) patients. The effects of symptoms on death have been investigated, but symptoms were considered individually, rather than in combination, as predictors. We examined the effects of symptom combinations on in-hospital mortality. ...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,018,728
Screening for Child Abuse in Children With Isolated Skull Fractures.
Pediatric emergency care
Pediatr Emerg Care
39
6
10.1097/PEC.0000000000002823
eng
2,023
6
1
2,022
8
26
[OBJECTIVE] Head trauma is the most common cause of death from child abuse, and each encounter for recurrent abuse is associated with greater morbidity. Isolated skull fractures (ISF) are often treated conservatively in the emergency department (ED). We determined patterns of physical abuse screening in a children's ho...
null
0.489
79
Emergency Medicine; Pediatrics, Perinatology and Child Health; Medicine
Medicine
2,023
36,018,575
Phenomenology of anxiety in people living with mild to moderate dementia: A conceptual meta-ethnographic review.
Dementia (London, England)
Dementia (London)
21
8
10.1177/14713012221123706
eng
2,022
11
null
2,022
8
26
[OBJECTIVES] This conceptual review aims to integrate findings from published qualitative studies focusing on individual experiences of people living with dementia to generate a better understanding and conceptualisation of anxiety in dementia, including its subclinical manifestations. The review aims to inform the cli...
anxiety; cognitive impairment; conceptual framework of anxiety in dementia; dementia; meta-ethnography; qualitative interpretive synthesis; worry; worry themes in dementia
0.942
70
History; Medicine; Social Sciences; Sociology and Political Science
Arts and Humanities; Medicine; Social Sciences
2,022
36,018,230
Impact of initial therapy with upadacitinib or adalimumab on achievement of 48-week treatment goals in patients with rheumatoid arthritis: post hoc analysis of SELECT-COMPARE.
Rheumatology (Oxford, England)
Rheumatology (Oxford)
62
5
10.1093/rheumatology/keac477
eng
2,023
5
2
null
null
null
[OBJECTIVES] Evaluate the importance of treatment sequencing in SELECT-COMPARE, assessing potential differences between starting upadacitinib or adalimumab therapy following inadequate MTX response. [METHODS] Patients from SELECT-COMPARE were randomized to upadacitinib 15 mg once daily, placebo or adalimumab 40 mg. Per...
JAK inhibitors; RA; bDMARD; clinical trials; treat-to-target; treatment strategy
1.721
205
Pharmacology; Rheumatology
Medicine
2,023
36,018,229
The impact of sodium-glucose cotransporter inhibitors on blood pressure: a meta-analysis and metaregression of 111 randomized-controlled trials.
Journal of hypertension
J Hypertens
40
12
10.1097/HJH.0000000000003280
eng
2,022
12
1
2,022
8
22
[OBJECTIVE] Multiple trials on sodium-glucose cotransporter (SGLT) inhibitors have been performed recently demonstrating blood pressure (BP) reduction benefits in both diabetic and nondiabetic patients. Hence, we conducted a systematic review and meta-analysis to determine the effect of different SGLT inhibitors on BP ...
null
1.194
198
Cardiology and Cardiovascular Medicine; Internal Medicine; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,018,126
Independent risk factors of type III acute acquired concomitant esotropia: A matched case-control study.
Indian journal of ophthalmology
Indian J Ophthalmol
70
9
10.4103/ijo.IJO_318_22
eng
2,022
9
null
null
null
null
[PURPOSE] To investigate the risk factors and surgical design for type III acute acquired concomitant esotropia (AACE). [METHODS] In this retrospective, matched, case-control study, 51 patients developed type III AACE between March 2018 and September 2020, and the control group consisted of 60 patients matched by age a...
Acute Acquired Concomitant Esotropia; logic models; myopia; risk factors
0.666
79
Ophthalmology
Medicine
2,022
36,017,841
Detection of Acute Optic Neuritis using Contrast-Enhanced 3-Dimensional Cube T1-Weighted Imaging: A Preliminary Study.
Combinatorial chemistry high throughput screening
Comb Chem High Throughput Screen
26
8
10.2174/1386207325666220823121312
eng
2,023
null
null
null
null
null
[UNLABELLED] Objective; We aimed to assess whole-brain imaging with contrast-enhanced (CE) 3- dimensional (3D) Cube T1WI in improving the diagnostic accuracy of acute optic neuritis (ON) compared to conventional CE 2-dimensional (2D) T1WI. [METHODS] At a field strength of 3 T, CE 3D Cube T1-weighted and conventional CE...
3-dimensional fast spin echo; Magnetic resonance imaging; cube; optic neuritis; variable flip angle; whole-brain imaging
null
null
null
null
null
36,017,734
Work-up and Management of Asymptomatic Extracranial Traumatic Vertebral Artery Injury.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
Can J Neurol Sci
50
5
10.1017/cjn.2022.292
eng
2,023
9
null
2,022
8
26
[BACKGROUND] Non-penetrating head and neck trauma is associated with extracranial traumatic vertebral artery injury (eTVAI) in approximately 1-2% of cases. Most patients are initially asymptomatic but have an increased risk for delayed stroke and mortality. Limited evidence is available to guide the management of asymp...
Interventional neuroradiology; Neuroimaging; Neurosurgery; Neurosurgery - vascular; Neurotrauma; Neurovascular; Spinal Trauma; Spine; Trauma; Vascular
null
null
null
null
null
36,017,140
The effect of the COVID-19 pandemic on the outcomes of surgically treated colorectal diseases: a retrospective cohort study.
Annals of surgical treatment and research
Ann Surg Treat Res
103
2
10.4174/astr.2022.103.2.104
eng
2,022
8
null
2,022
8
5
[PURPOSE] The objective of this study is to evaluate the effect of the coronavirus disease 2019 (COVID-19) pandemic on elective and emergent colorectal surgical practice. [METHODS] The population of this retrospective observational study consisted of all consecutive patients who underwent emergent or elective colorecta...
COVID-19; Colorectal surgery; Morbidity; Mortality
0.421
37
Surgery
Medicine
2,022
36,012,869
Fungal Infections in the ICU during the COVID-19 Era: Descriptive and Comparative Analysis of 178 Patients.
Journal of fungi (Basel, Switzerland)
J Fungi (Basel)
8
8
10.3390/jof8080881
eng
2,022
8
21
2,022
8
21
[BACKGROUND] COVID-19-associated fungal infections seem to be a concerning issue. The aim of this study was to assess the incidence of fungal infections, the possible risk factors, and their effect on outcomes of critically ill patients with COVID-19. [METHODS] A retrospective observational study was conducted in the C...
CAC; CAPA; COVID-19; ICU; SARS-CoV-2; fungal infection
0.871
78
Ecology, Evolution, Behavior and Systematics; Plant Science; Microbiology
Agricultural and Biological Sciences; Medicine
2,022
36,011,655
Electroencephalography-Based Neuroemotional Responses in Cognitively Normal and Cognitively Impaired Elderly by Watching the Ardisia mamillata Hance with Fruits and without Fruits.
International journal of environmental research and public health
Int J Environ Res Public Health
19
16
10.3390/ijerph191610020
eng
2,022
8
14
2,022
8
14
[BACKGROUND] The purpose of this study is to explore the difference between the indexes of neuro-emotion between the cognitively normal elderly (CNE) and cognitively impaired elderly (CIE) while viewing the Ardisia mamillata Hance with red fruit (F) and without red fruit (NF) to determine which kind of the Ardisia mami...
Ardisia mamillata Hance; EEG; elderly; fruit plants; neural emotion
0.828
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,022
36,010,988
Management of Recurrent Meningiomas: State of the Art and Perspectives.
Cancers
Cancers (Basel)
14
16
10.3390/cancers14163995
eng
2,022
8
18
2,022
8
18
[BACKGROUND] While meningiomas often recur over time, the natural history of repeated recurrences and their management are not well described. Should recurrence occur, repeat surgery and/or use of adjuvant therapeutic options may be necessary. Here, we summarize current practice when it comes to meningioma recurrence a...
meningioma; overall survival; progression-free survival; recurrence; retreatment
1.312
157
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,010,398
Allicin Promoted Reducing Effect of Garlic Powder through Acrylamide Formation Stage.
Foods (Basel, Switzerland)
Foods
11
16
10.3390/foods11162394
eng
2,022
8
10
2,022
8
10
[BACKGROUND] Acrylamide is formed during food heating and is neurotoxic to animals and potentially carcinogenic to humans. It is important to reduce acrylamide content during food processing. Researchers have suggested that garlic powder could reduce acrylamide content, but the key substance and acrylamide reduction pa...
Maillard reaction; acrylamide; allicin; garlic powder; kinetics evaluation
null
null
null
null
null
36,010,017
Clinical Characteristics of Venous Thrombosis Associated with Peripherally Inserted Central Venous Catheter in Premature Infants.
Children (Basel, Switzerland)
Children (Basel)
9
8
10.3390/children9081126
eng
2,022
7
28
2,022
7
28
[BACKGROUND] This study aimed to analyze clinical characteristics and risk factors for peripherally inserted central catheter (PICC) placement in premature infants. [MATERIALS] This study included seven premature infants who were hospitalized in the neonatal intensive care unit (NICU) of Peking University Third Hospita...
anticoagulation therapy; autoimmune disease; preterm infants; venous thrombosis
0.504
56
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,008,173
Functional and radiological outcomes of primary ring fixator versus antibiotic nail in open tibial diaphyseal fractures: A prospective study.
Injury
Injury
53
10
10.1016/j.injury.2022.08.020
eng
2,022
10
null
2,022
8
9
[BACKGROUND] Management of open fractures of tibia is still a matter of debate due to high incidence of infections. Traditionally external fixators have been advocated in managing open tibial fractures. Due to limited efficacy of systemic antibiotics, recently antibiotic coated intramedullary interlocking nails have be...
Antibiotic nail; Complications; Infection; Ring fixator; Tibia fracture
0.698
151
Surgery; Emergency Medicine; Orthopedics and Sports Medicine
Medicine
2,022
36,007,715
Natural History of MYH7-Related Dilated Cardiomyopathy.
Journal of the American College of Cardiology
J Am Coll Cardiol
80
15
10.1016/j.jacc.2022.07.023
eng
2,022
10
11
2,022
8
22
[BACKGROUND] Variants in myosin heavy chain 7 (MYH7) are responsible for disease in 1% to 5% of patients with dilated cardiomyopathy (DCM); however, the clinical characteristics and natural history of MYH7-related DCM are poorly described. [OBJECTIVES] We sought to determine the phenotype and prognosis of MYH7-related ...
MYH7; dilated cardiomyopathy; genetics
8.343
512
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,007,594
The right prefrontal cortex (PFC) can distinguish anxious depression from non-anxious depression: A promising functional near infrared spectroscopy study (fNIRS).
Journal of affective disorders
J Affect Disord
317
null
10.1016/j.jad.2022.08.024
eng
2,022
11
15
2,022
8
22
[BACKGROUND] Anxious depression is a serious mental disorder characterized by comorbidity of anxiety and depression, and its symptoms are similar to those of non-anxious depression. This study aimed to use functional near-infrared spectroscopy (fNIRS) as a tool to distinguish between patients with anxious and non-anxio...
Anxious depression; Dorsolateral prefrontal cortex; Frontopole cortex; Functional near infrared spectroscopy; Verbal fluency
1.988
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
36,007,408
Bladder leiomyoma treated with transurethral resection of bladder tumor (TURBT): Case report.
International journal of surgery case reports
Int J Surg Case Rep
98
null
10.1016/j.ijscr.2022.107464
eng
2,022
9
null
2,022
7
30
[INTRODUCTION AND IMPORTANCE] Bladder leiomyomas are rare benign mesenchymal tumors, accounting only about 0.43 % of all bladder tumors. These tumors are classified based on their location, where they can be endovesical, extravesical, and intramural with the endovesical subtype being the most common. There are roughly ...
Bladder leiomyoma; Case report; Transurethral resection of bladder tumor (TURBT); Urology
0.193
31
Surgery
Medicine
2,022
36,007,278
Oviduct-mimicking microfluidic chips decreased the ROS concentration in the in vitro fertilized embryos of CD-1 mice.
Biomedicine pharmacotherapy = Biomedecine pharmacotherapie
Biomed Pharmacother
154
null
10.1016/j.biopha.2022.113567
eng
2,022
10
null
2,022
8
22
[BACKGROUND] The process of the assisted reproductive technology (ART) cycle is extremely complicated, and various factors in each step may influence the final clinical outcomes; thus, optimizing culture conditions for embryos is crucial in the ART cycle, particularly when the traditional petri-dish method remains unch...
Embryo culture; Microfluidic; Organ-on-chip; Oviduct; Reactive oxygen species
null
null
null
null
null
36,006,851
Inverse relationship between IL-6 and sodium levels in patients with COVID-19 and other respiratory tract infections: data from the COVIVA study.
Endocrine connections
Endocr Connect
11
10
10.1530/EC-22-0171
eng
2,022
10
1
2,022
9
26
[OBJECTIVE] Hyponatremia in COVID-19 is often due to the syndrome of inadequate antidiuresis (SIAD), possibly mediated by interleukin-6 (IL-6)-induced non-osmotic arginine vasopressin (AVP) secretion. We hypothesized an inverse association between IL-6 and plasma sodium concentration, stronger in COVID-19 compared to o...
COVID-19; CRP; PCT; hyponatremia; interleukin-6
0.76
50
Endocrinology; Endocrinology, Diabetes and Metabolism; Internal Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,006,606
Cost-Utility of Nivolumab Plus Ipilimumab in First-Line Treatment of Advanced Melanoma in the United States: An Analysis Using Long-Term Overall Survival Data from Checkmate 067.
PharmacoEconomics - open
Pharmacoecon Open
6
5
10.1007/s41669-022-00348-0
eng
2,022
9
null
2,022
8
25
[OBJECTIVE] The aim of this study was to evaluate the cost-utility of nivolumab plus ipilimumab (NIVO + IPI) versus other first-line therapies for advanced melanoma in the United States (US) from the third-party payer perspective. [METHODS] This analysis estimated total expected life-years (LYs), quality-adjusted LYs (...
null
0.646
24
Health Policy; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,006,417
Does treatment of lichen sclerosus improve overactive bladder symptoms?
International urogynecology journal
Int Urogynecol J
34
6
10.1007/s00192-022-05318-y
eng
2,023
6
null
2,022
8
25
[INTRODUCTION AND HYPOTHESIS] Lichen sclerosus (LS) is a chronic disease which mainly affects the vulvar area in women. A few studies have shown a possible relationship between LS and overactive bladder (OAB) symptoms, but no studies have investigated whether OAB symptoms improve after initiating treatment of LS. The a...
Lichen sclerosus; Local steroid; OAB symptoms
0.821
109
Urology; Obstetrics and Gynecology
Medicine
2,023
36,006,219
Real-World Longitudinal Experience of Botulinum Toxin Therapy for Parkinson and Essential Tremor.
Toxins
Toxins (Basel)
14
8
10.3390/toxins14080557
eng
2,022
8
17
2,022
8
17
[BACKGROUND] Botulinum toxin type A (BoNT-A) therapy for upper-limb tremor has emerged as a promising option. However, it is unclear in real-world practices whether a technology-guided approach can compare with expert clinical assessments (including surface anatomy and palpation) for improving outcomes. This retrospect...
Botulinum toxin; essential tremor; treatment; upper-limb tremor
0.87
128
Toxicology; Health, Toxicology and Mutagenesis
Environmental Science; Pharmacology, Toxicology and Pharmaceutics
2,022
36,004,768
Masticatory function of stroke patients: A systematic review with meta-analysis.
Gerodontology
Gerodontology
40
2
10.1111/ger.12653
eng
2,023
6
null
2,022
8
25
[PURPOSE] The present systematic review and meta-analysis aimed to summarise the current information on the masticatory function of stroke patients. [METHODS] Four electronic databases (Medline, Embase, CINAHL and Web of Science) were searched for relevant observational studies and clinical trials (up to Jun 2021) on t...
bite force; mastication; masticatory muscles; stroke
0.609
69
Dentistry; Geriatrics and Gerontology
Dentistry; Medicine
2,023
36,004,609
Direct Plantar Approach to Plantar Plate Repair and Associated Wound Complications.
Foot ankle specialist
Foot Ankle Spec
18
1
10.1177/19386400221118500
eng
2,025
2
null
2,022
8
25
[BACKGROUND] Lesser toe metatarsophalangeal joint (MTPJ) instability, secondary to plantar plate tear, has been the focus of numerous recent publications, the majority reporting on repair through a dorsal approach. A plantar approach has been described with the advantage of direct ligamentous repair or repair to bone, ...
MTP plantar plate repair; hammer toe deformity; wound complications
null
null
null
null
null
36,004,235
Early and late outcomes of type A acute aortic dissection with common carotid artery involvement.
JTCVS open
JTCVS Open
10
null
10.1016/j.xjon.2022.01.024
eng
2,022
6
null
2,022
2
23
[OBJECTIVE] The relationship between common carotid artery (CCA) involvement in acute type A aortic dissection (ATAAD) and postoperative outcomes remains unclear. We investigated outcomes and described our current advanced strategy. [METHODS] Of 492 patients who underwent surgical repair for ATAAD between September 199...
ATAAD, acute type A aortic dissection; BSS, brain-saving system; CCA, common carotid artery; CT, computed tomography; ICA, internal carotid artery; IQR, interquartile range; PND, persistent neurologic deficit; TND, transient neurologic deficit; aortic dissection; carotid artery; cerebral perfusion; mRS, modified Rankin...
0.291
15
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,022
36,003,993
A Web-Based Pharmacological Approach to the Mechanism of Action of Rhizoma Phragmitis and Rhizoma Curcumae in the Treatment of Chronic Atrophic Gastritis.
Contrast media molecular imaging
Contrast Media Mol Imaging
2022
null
10.1155/2022/3483774
eng
2,022
null
null
2,022
8
10
[OBJECTIVE] To analyze and test the effect of Rhizoma phragmitis and Rhizoma curcumae on the network pharmacology of MAPK (mitogen-activated protein kinase) and TNF (tumor necrosis factor) signaling channels and inflammatory factor target gene regulation in successful modeling of chronic atrophic gastritis rats. [METHO...
null
null
null
null
null
null
36,003,923
Association between speech rate measures and cognitive function in people with relapsing and progressive multiple sclerosis.
Multiple sclerosis journal - experimental, translational and clinical
Mult Scler J Exp Transl Clin
8
3
10.1177/20552173221119813
eng
2,022
null
null
2,022
8
17
[BACKGROUND] Cognitive impairments are well-documented in multiple sclerosis (MS), while speech impairments are often overlooked despite their significant effect on quality of life. For effective clinical management of multisystem conditions such as MS, consideration should be given to the interaction between deficits ...
cognition; information processing; multiple sclerosis; regression; spontaneous speech
0.714
34
Neurology; Cellular and Molecular Neuroscience
Medicine; Neuroscience
2,022
36,003,922
The Validity of Ultrasonographic Measurements of the Rectus Femoris Muscle in Older Adults with Sarcopenia in Thai Population.
Clinical interventions in aging
Clin Interv Aging
17
null
10.2147/CIA.S375419
eng
2,022
null
null
2,022
8
18
[PURPOSE] This study aimed to determine the validity of ultrasonographic measurement of the rectus femoris muscle (RFM) thickness as a screening tool for low appendicular muscle mass (ASM) to diagnose sarcopenia and to determine the cut-off point of RFM thickness in the Thai population. [PATIENTS AND METHODS] We enroll...
bioelectrical impedance; rectus femoris muscle; sarcopenia; ultrasonography
0.923
114
Medicine; Geriatrics and Gerontology
Medicine
2,022
36,003,834
Nutritional aspects in chronic non-cancer pain: A systematic review.
Frontiers in nutrition
Front Nutr
9
null
10.3389/fnut.2022.931090
eng
2,022
null
null
2,022
8
8
[OBJECTIVES] Chronic pain (CP) is an unpleasant emotional and sensory experience that can be accompanied by tissue damage that persists for more than 3 months. Recent studies show that certain nutritional strategies can help to improve pain, so this study is aimed to systematically review scientific evidence to underst...
chronic pain; diet; feeding; nutrients; nutrition; supplements
0.875
94
Food Science; Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Agricultural and Biological Sciences; Medicine; Nursing
2,022
36,003,781
Predicting chemotherapy response in non-small-cell lung cancer via computed tomography radiomic features: Peritumoral, intratumoral, or combined?
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.915835
eng
2,022
null
null
2,022
8
8
[PURPOSE] This study aims to evaluate the ability of peritumoral, intratumoral, or combined computed tomography (CT) radiomic features to predict chemotherapy response in non-small cell lung cancer (NSCLC). [METHODS] After excluding subjects with incomplete data or other types of treatments, 272 (Dataset 1) and 43 (Dat...
Computed Tomography (CT); area under curve; chemotherapy response; non-small cell lung cancer; peritumoral features; radiomics
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,003,471
The acute influence of vasopressin on hemodynamic status and tissue oxygenation following the Norwood procedure.
JTCVS open
JTCVS Open
9
null
10.1016/j.xjon.2022.01.008
eng
2,022
3
null
2,022
1
22
[OBJECTIVES] Arginine vasopressin (AVP) is used to treat hypotension. Because AVP increases blood pressure by increasing systemic vascular resistance, it may have an adverse effect on tissue oxygenation following the Norwood procedure. [METHODS] Retrospective analysis of continuously captured hemodynamic data of neonat...
ANOVA, analysis of variance; AVP, arginine vasopressin; BP, blood pressure; BTS, Blalock-Taussig shunt; CAP, common atrial pressure; CO, cardiac output; CPP, coronary perfusion pressure; HR, heart rate; NIRS, near infrared spectroscopy; NP, Norwood procedure; Norwood procedure; O2ER, oxygen extraction ratio; PVR, pulmo...
0.291
15
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,022
36,003,364
Co-isolates of Acinetobacter baumannii complex in polymicrobial infections: a meta-analysis.
Access microbiology
Access Microbiol
4
5
10.1099/acmi.0.000348
eng
2,022
8
null
2,022
5
9
[UNLABELLED] Background. Acinetobacter baumannii complex (ABC) infections are commonly polymicrobial. Examining which pathogens are most commonly co-isolated with ABC is an important first step for assessing disease potential due to pathogen-pathogen interactions. Methods. Based on a systematic search of PubMed, Scopus...
Acinetobacter; Pseudomonas; bacteremia; pneumonia; polymicrobial
null
null
null
null
null
36,003,257
Health protection challenges of slums residents during the COVID-19 pandemic, according to the social determinants of health framework: A case study of Kerman city in Iran.
Journal of education and health promotion
J Educ Health Promot
11
null
10.4103/jehp.jehp_958_21
eng
2,022
null
null
2,022
6
30
[BACKGROUND] Coronavirus disease-2019 (COVID-19) pandemic can aggravate the health problems in slum areas. The present study intends to examine the challenges of health protection of slum's residences during the COVID-19 pandemic with the Social Determinants of Health perspective, in Kerman city in Iran. [MATERIALS AND...
Coronavirus disease; Iran; Kerman; coronavirus disease-19; slum; social determinants of health; suburban
0.411
30
Education; Medicine
Medicine; Social Sciences
2,022