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36,003,039
Mortality from angiotensin-converting enzyme-inhibitors and angiotensin receptor blockers in people infected with COVID-19: a cohort study of 3.7 million people.
Family practice
Fam Pract
40
2
10.1093/fampra/cmac094
eng
2,023
3
28
null
null
null
[BACKGROUND] Concerns have been raised that angiotensin-converting enzyme-inhibitors (ACE-I) and angiotensin receptor blockers (ARBs) might facilitate transmission of severe acute respiratory syndrome coronavirus 2 leading to more severe coronavirus disease (COVID-19) disease and an increased risk of mortality. We aime...
COVID-19; medication; mortality
0.917
116
Family Practice
Medicine
2,023
36,002,803
The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysis.
BMC pediatrics
BMC Pediatr
22
1
10.1186/s12887-022-03545-2
eng
2,022
8
24
2,022
8
24
[BACKGROUND] This study is a systematic review and meta-analysis on published studies about the Global Survival Rate of Graft and Patients in the Kidney Transplantation of children. [METHODS] Studies that investigated the survival rate of kidney transplants published until the 30th of December 2020 were selected using ...
Graft survival; Kidney transplantation; Meta-analysis; Patient survival
0.742
106
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,002,795
Effects of visual scanning exercises in addition to task specific approach on balance and activities of daily livings in post stroke patients with eye movement disorders: a randomized controlled trial.
BMC neurology
BMC Neurol
22
1
10.1186/s12883-022-02843-7
eng
2,022
8
24
2,022
8
24
[BACKGROUND] Impaired vision is one of the commonest and most disabling consequence following stroke. Among all visual impairments, eye movement disorders are found in 70% of stroke patients which include nystagmus, strabismus, gaze palsies, disconjugate eye movements and cranial nerve palsies. They have a wide ranging...
Eye movement disorders; Stroke; Task specific approach; Visual scanning exercises
0.771
100
Medicine; Neurology
Medicine
2,022
36,002,699
Trend Changes in the individual contribution of risk factors for postpartum hemorrhage over more than two decades.
Maternal and child health journal
Matern Child Health J
26
11
10.1007/s10995-022-03461-y
eng
2,022
11
null
2,022
8
24
[OBJECTIVE] Postpartum hemorrhage is an obstetric emergency with a rising incidence. The aim of this study was to identify trends in the specific contribution of various risk factors for postpartum hemorrhage by observing their odds ratios throughout different time periods. [STUDY DESIGN] In this population-based retro...
Large for gestational age; Perineal tear; Postpartum hemorrhage; Vaginal tear
0.784
109
Pediatrics, Perinatology and Child Health; Epidemiology; Obstetrics and Gynecology; Public Health, Environmental and Occupational Health
Medicine
2,022
36,002,353
Role of preoperative CT angiography with multimodality imaging reconstruction to perform laparoscopic Complete Mesocolic Excision (CME) and Central Vascular Ligation (CVL) in right-sided colon cancer: Is it really useful? A prospective clinical study.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Eur J Surg Oncol
49
1
10.1016/j.ejso.2022.08.007
eng
2,023
1
null
2,022
8
17
[BACKGROUND] The concept of complete mesocolic excision (CME) and central vascular ligation (CVL) in right colonic resections appears to improve the oncological outcomes. The highest rate of complications reported in the literature in patients undergoing CME is related to difficult surgical manuevers and intraoperative...
Central vascular ligation; Colon cancer; Colonic resection; Complete mesocolic excision; Laparoscopy
1.164
123
Medicine; Surgery; Oncology
Medicine
2,023
36,002,216
Troponin and short-term mortality in hospitalised patients with COVID-19 infection: a retrospective study in an inner-city London hospital.
BMJ open
BMJ Open
12
8
10.1136/bmjopen-2022-061426
eng
2,022
8
24
2,022
8
24
[OBJECTIVE] To investigate the association between troponin positivity in patients hospitalised with COVID-19 and increased mortality in the short term. [SETTING] Homerton University Hospital, an inner-city district general hospital in East London. [DESIGN] A single-centre retrospective observational study. [PARTICIPAN...
COVID-19; cardiology; public health
1.059
176
Medicine
Medicine
2,022
36,002,152
The epidemiology of eye injuries in Western Australia: a retrospective 10-year study.
Clinical experimental optometry
Clin Exp Optom
106
6
10.1080/08164622.2022.2111198
eng
2,023
8
null
2,022
8
24
[CLINICAL RELEVANCE] Eye injuries constitute a significant cause of preventable lifelong visual impairment or blindness. It is important to identify the context in which these injuries occur to develop intervention programs to reduce the incidence and severity of injury. [BACKGROUND] To evaluate the nature, external ca...
Epidemiology; eye injuries
null
null
null
null
null
36,002,118
Model-free digital workflow and immediate functional loading of implant-supported monolithic glass-ceramic crowns: A case series.
Journal of dentistry
J Dent
125
null
10.1016/j.jdent.2022.104270
eng
2,022
10
null
2,022
8
21
[OBJECTIVES] The aim of this study was to evaluate surgical and prosthetic outcomes of immediate functional loading of implants with glass-ceramic screw-retained single crowns. [METHODS] A total of 22 implants were placed. Within 24 h, functional full-contour glass ceramic crowns were delivered to patients. The amount ...
Digital workflow; Immediate loading; Implant dentistry
1.189
146
Dentistry
Dentistry
2,022
36,001,910
Expressive vocabulary of school-age children with mild to moderately severe hearing loss.
International journal of pediatric otorhinolaryngology
Int J Pediatr Otorhinolaryngol
162
null
10.1016/j.ijporl.2022.111281
eng
2,022
11
null
2,022
8
17
[OBJECTIVES] The main goal of this study was to describe the expressive vocabulary of school-age children with mild to moderately severe hearing loss (CHL group) and to compare their performance with children with normal hearing (CNH group) of the same age. Another aim was to examine the interaction between nonword rep...
Mild to moderately severe hearing loss; Nonword repetition and expressive vocabulary size; Vocabulary; children
0.554
96
Medicine; Otorhinolaryngology; Pediatrics, Perinatology and Child Health
Medicine
2,022
36,001,699
Wound tissue segmentation by computerised image analysis of clinical pressure injury photographs: a pilot study.
Journal of wound care
J Wound Care
31
8
10.12968/jowc.2022.31.8.710
eng
2,022
8
2
null
null
null
[OBJECTIVE] Wound tissues can provide ample information about the wound development and healing process. However, the manual identification and measurement of wound tissue types is time-consuming and challenging due to the complexities of pressure injuries (PI). This study aims to develop an image analysis algorithm to...
image analysis; nursing assessment; pressure injury; pressure ulcer; wound; wound bed; wound care; wound dressing; wound healing; wound tissue
0.459
83
Fundamentals and Skills; Nursing
Nursing
2,022
36,001,236
Effect of self-perceived oral habits on orofacial dysfunction and oral health-related quality of life among a group of Egyptian children: a cohort study.
European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry
Eur Arch Paediatr Dent
23
6
10.1007/s40368-022-00740-8
eng
2,022
12
null
2,022
8
24
[PURPOSE] This study aims to investigate the relationship between OHRQoL and orofacial dysfunction in children practicing oral habits. [METHODS] Thirty Egyptian Children, aged from five to seven years, practicing oral habits (habit practicing/exposed group), were examined for orofacial dysfunction using Nordic Orofacia...
Children; Oral habits; Oral health-related quality of life; Orofacial dysfunction
0.593
55
Dentistry; Pediatrics, Perinatology and Child Health
Dentistry; Medicine
2,022
36,000,683
Could CA 19-9 be a useful biomarker in the diagnosis, prognosis, and prediction of adequate relief in lower urinary tract obstructions?
Revista do Colegio Brasileiro de Cirurgioes
Rev Col Bras Cir
49
null
10.1590/0100-6991e-20223304-en
eng
2,022
null
null
2,022
8
22
[INTRODUCTION] posterior urethral valves represent an important cause of childhood chronic kidney disease. The identification of biomarkers that indicate early kidney damage and even adequate clearance could reduce how many patients head towards kidney failure. [OBJECTIVE] this study evaluated how this easy-analysis bi...
null
null
null
null
null
null
36,000,474
Phasicity and resistance of the arterial spectral Doppler waveform in a canine femoral focal artery stenosis model.
Vascular medicine (London, England)
Vasc Med
27
6
10.1177/1358863X221117608
eng
2,022
12
null
2,022
8
24
[INTRODUCTION] This study aims to evaluate changes in the arterial spectral Doppler waveform in a canine artery stenosis model. [METHODS] Canine femoral artery stenosis models were established in 12 beagle dogs. Doppler waveforms were recorded in the femoral artery preoperatively and postoperatively in the femoral arte...
animal model; arterial stenosis; femoral artery; phasicity; resistance; spectral Doppler waveform; ultrasound
0.832
86
Cardiology and Cardiovascular Medicine; Medicine
Medicine
2,022
36,000,466
Care-resistant behaviour during oral examination in Dutch nursing home residents with dementia.
Gerodontology
Gerodontology
40
3
10.1111/ger.12654
eng
2,023
9
null
2,022
8
24
[OBJECTIVE] To assess the occurrence and associations of verbal and non-verbal care-resistant behaviour (CRB) during oral examination by a dental hygienist in nursing home residents with dementia. [BACKGROUND] CRB is a barrier to providing professional oral care and daily oral hygiene care. Understanding the predictors...
care-resistant behaviour; dementia; nursing home; oral examination
0.609
69
Dentistry; Geriatrics and Gerontology
Dentistry; Medicine
2,023
36,000,272
Childhood Adversity and Mental Health Outcomes Among University Students: A Longitudinal Study.
Canadian journal of psychiatry. Revue canadienne de psychiatrie
Can J Psychiatry
68
7
10.1177/07067437221111368
eng
2,023
7
null
2,022
8
24
[BACKGROUND] Mental health concerns are common among university students and maybe elevated among those with specific risk exposures. The study examined the association between childhood adversities and mental health outcomes among undergraduate university students and assessed whether psychosocial and behavioral facto...
childhood abuse; childhood adversity; parental separation or divorce; prevention and early intervention; student mental health
null
null
null
null
null
36,000,030
Evaluation of substance P and bradykinin levels in nasal secretions of patients with nasal polyposis with and without sensitivity to non-steroidal anti-inflammatory drugs.
Laryngoscope investigative otolaryngology
Laryngoscope Investig Otolaryngol
7
4
10.1002/lio2.851
eng
2,022
8
null
2,022
6
29
[OBJECTIVE] The role of neurogenic inflammation in pathogenesis of chronic rhinitis is well known. However, very little is known about its importance in pathogenesis of nasal polyposis (NP), especially in form of NP which appears as a part of aspirin-exacerbated respiratory disease (AERD). The aim of this study was to ...
aspirin; bradykinin; hypersensitivity; nasal polyps; neurogenic inflammation; sinusitis; substance P
0.701
42
Otorhinolaryngology; Surgery
Medicine
2,022
35,999,617
AZTEC-azithromycin therapy for prevention of chronic lung disease of prematurity: a statistical analysis plan for clinical outcomes.
Trials
Trials
23
1
10.1186/s13063-022-06604-2
eng
2,022
8
23
2,022
8
23
[BACKGROUND] The AZTEC trial is a multi-centre, randomised, placebo-controlled trial of azithromycin to improve survival without development of chronic lung disease of prematurity (CLD) in preterm infants. The statistical analysis plan for the clinical outcomes of the AZTEC trial is described. [METHODS AND DESIGN] A do...
Azithromycin; Bronchopulmonary dysplasia; Chronic lung disease of prematurity; Macrolide; Preterm infants; Randomised controlled trial; Statistical analysis plan
0.814
103
Medicine; Pharmacology
Medicine
2,022
35,999,600
Efficacy of SCF drug conjugate targeting c-KIT in gastrointestinal stromal tumor.
BMC medicine
BMC Med
20
1
10.1186/s12916-022-02465-3
eng
2,022
8
24
2,022
8
24
[BACKGROUND] Gastrointestinal stromal tumor (GIST) is a rare type of cancer that occurs in the gastrointestinal tract. The majority of GIST cases carry oncogenic forms of KIT, the receptor for stem cell factor (SCF). Small molecule kinase inhibitor imatinib is effective in prolonging the survival of GIST patients by ta...
DM1; GIST; SCF; Targeted therapy
3.447
199
Medicine
Medicine
2,022
35,999,489
Neuroanatomy and Functional Connectivity in Patients with Parkinson's Disease with or without Restless Legs Syndrome.
Neurology and therapy
Neurol Ther
11
4
10.1007/s40120-022-00397-x
eng
2,022
12
null
2,022
8
23
[INTRODUCTION] Restless legs syndrome (RLS) is a common non-motor symptom in Parkinson's disease (PD), but its pathogenesis remains unclear. This study aimed to explore the potential neural substrates of RLS in a large sample of patients with PD. [METHODS] A total of 42 patients with PD with RLS and 124 patients with P...
Functional connectivity; Posterior cingulate gyrus; Restless legs syndrome; fMRI
0.923
41
Neurology; Neurology
Medicine; Neuroscience
2,022
35,999,465
Health Utility Measures Among Patients with Androgenetic Alopecia After Hair Transplant.
Aesthetic plastic surgery
Aesthetic Plast Surg
47
2
10.1007/s00266-022-03066-4
eng
2,023
4
null
2,022
8
23
[BACKGROUND] Hair loss causes significant psychosocial distress to patients. Health utility measurements offer an objective, quantitative assessment of health-related quality of life (QOL). [METHODS] We performed a prospective cohort study on patients with hair loss between January 1, 2018 and December 31, 2020. Patien...
Alopecia; Hair loss; Hair transplant; Health state utility; Quality of life
0.909
85
Surgery
Medicine
2,023
35,999,271
Patient trajectories after diagnosis of diffuse large B-cell lymphoma-a multistate modelling approach to estimate the chance of lasting remission.
British journal of cancer
Br J Cancer
127
9
10.1038/s41416-022-01931-2
eng
2,022
11
null
2,022
8
23
[BACKGROUND] Achieving lasting remission for at least 2 years is a good indicator for favourable prognosis long term after Diffuse large B-cell lymphoma (DLBCL). The aim of this study was to provide real-world probabilities, useful in risk communication and clinical decision-making, of the chance for lasting remissions...
null
2.867
281
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,999,163
Efficacy and safety of polaprezinc in the treatment of gastric ulcer: A multicenter, randomized, double-blind, double-dummy, positive-controlled clinical trial.
Medical engineering physics
Med Eng Phys
110
null
10.1016/j.medengphy.2022.103860
eng
2,022
12
null
2,022
8
12
[OBJECTIVE] To investigate the clinical efficacy and safety of polaprezinc compared with rebamipide in the treatment of gastric ulcers (GU). [METHODS] GU patients (n = 224) from 10 clinical centers were prospectively enrolled and randomly divided into a control (n = 113) or test (n = 111) group. The control group was t...
Efficacy; Gastric ulcer; Gastroscopy; Granules; Polaprezinc; Rebamipide; Safety
null
null
null
null
null
35,999,034
Performance evaluation and clinical impact of the Oncomine Myeloid Research Assay for gene expression analysis in myeloid haematologic malignancies.
Journal of clinical pathology
J Clin Pathol
76
11
10.1136/jcp-2022-208425
eng
2,023
11
null
2,022
8
23
[AIM] Gene expression analysis facilitates the detection of diagnostic and prognostic biomarkers for myeloid haematological malignancies. The Oncomine Myeloid Research Assay (OMA; Thermo Fisher Scientific, Massachusetts, USA) provides a comprehensive analysis of gene expression of five target genes, along with gene alt...
Biomarkers, Tumor; Diagnostic Techniques and Procedures; Leukemia, Myeloid; Myelodysplastic Syndromes
0.934
158
Medicine; Pathology and Forensic Medicine
Medicine
2,023
35,998,351
Roles of socioeconomic status, ethnicity and teacher beliefs in academic grading.
The British journal of educational psychology
Br J Educ Psychol
93
1
10.1111/bjep.12541
eng
2,023
3
null
2,022
8
23
[BACKGROUND] Educational outcomes in the United Kingdom vary as a function of students' family background, with those of lower socioeconomic status (SES) and certain ethnic minority groups among the worst affected. [AIMS] This pre-registered study investigates: (i) whether knowledge about students' socioeconomic and et...
educational inequality; ethnicity; meritocracy; socioeconomic status; teacher bias
1.738
120
Developmental and Educational Psychology; Education
Psychology; Social Sciences
2,023
35,998,280
Functional anatomy and echocardiographic assessment in secondary mitral regurgitation.
Journal of cardiac surgery
J Card Surg
37
12
10.1111/jocs.16863
eng
2,022
12
null
2,022
8
23
[BACKGROUND] Mitral valve apparatus is complex and involves the mitral annulus, the leaflets, the chordae tendinae, the papillary muscles as well as the left atrial and ventricular myocardium. Secondary mitral regurgitation is a consequence of regional or global left ventricle remodeling due to an acute myocardial infa...
clinical review
0.445
69
Surgery; Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022
35,998,074
Training in the protocol for robotic undocking for life emergency support (RULES) improves team communication, coordination and reduces the time required to decouple the robotic system from the patient.
The international journal of medical robotics + computer assisted surgery : MRCAS
Int J Med Robot
18
6
10.1002/rcs.2454
eng
2,022
12
null
2,022
9
3
[INTRODUCTION] Robotic surgery has expanded on it's surgical application and it is also noted an increase in surgical procedures complexity. Occurrence of emergency situations that require conversion of the minimally invasive access route to open access routes is uncommon. The urgent undocking of the robotic platform i...
emergency; haemorrhage; robotic surgery; simulation
null
null
null
null
null
35,997,977
Evaluation of Spending Differences Between Beneficiaries in Medicare Advantage and the Medicare Shared Savings Program.
JAMA network open
JAMA Netw Open
5
8
10.1001/jamanetworkopen.2022.28529
eng
2,022
8
1
2,022
8
1
[IMPORTANCE] The 2 primary efforts of Medicare to advance value-based care are Medicare Advantage (MA) and the fee-for-service-based Medicare Shared Savings Program (MSSP). It is unknown how spending differs between the 2 programs after accounting for differences in patient clinical risk. [OBJECTIVE] To examine how spe...
null
4.108
154
Medicine
Medicine
2,022
35,997,851
Identification of 45S rDNA in Passiflora using low coverage sequencing: analysis of GC content and chromosomal localization.
Molecular biology reports
Mol Biol Rep
49
9
10.1007/s11033-022-07686-6
eng
2,022
9
null
2,022
8
23
[BACKGROUND] The 45S rDNA is considered the most useful chromosomal marker for cytogenetic analysis of Passiflora. Amplification of 45S rDNA sequence via PCR are more advantageous than sequence maintenance in vectors for chromosomal hybridization via FISH. We aimed both to identify 45S rDNA by sequencing data for chrom...
Chromosome; Cytogenomics; Molecular cytogenetics; Next generation sequencing
0.578
96
Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,997,713
A crossover study evaluating the sex-dependent and sensitizing effects of sleep deprivation using a nociceptive test battery in healthy subjects.
British journal of clinical pharmacology
Br J Clin Pharmacol
89
1
10.1111/bcp.15505
eng
2,023
1
null
2,022
9
7
[AIM] We assessed whether total sleep deprivation (TSD) in combination with pain tests yields a reliable method to assess altered pain thresholds, which subsequently may be used to investigate (novel) analgesics in healthy subjects. [METHODS] This was a two-part randomized crossover study in 24 healthy men and 24 women...
drug development; pain; randomized controlled trial
1.046
176
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
35,997,690
Psychometric Evaluation of The Irritability Scale-Initial Version in Chinese Cancer Patients.
Nursing research
Nurs Res
72
1
10.1097/NNR.0000000000000615
eng
null
null
null
2,022
8
20
[BACKGROUND] Irritability is a common experience of depressed Chinese patients but is understudied and poorly measured. [OBJECTIVE] We aimed to assess psychometric properties of a new measure of irritability in Chinese cancer patients across the social and political spectrum. [METHODS] The Irritability Scale-Initial Ve...
null
null
null
null
null
null
35,997,210
Pilot proteomic study of locally advanced rectal cancer before and after neoadjuvant chemoradiotherapy indicates high metabolic activity in non-responders' tumor tissue.
Proteomics. Clinical applications
Proteomics Clin Appl
17
1
10.1002/prca.202100116
eng
2,023
1
null
2,022
9
7
[PURPOSE] In the search for candidate predictive biomarkers to evaluate response to neoadjuvant chemoradiotherapy (nCRT) in rectal cancer, only a few studies report proteomic profiles of tumor tissue before and after nCRT. The aim of our study was to determine differentially expressed proteins between responders and no...
biomarker; neoadjuvant chemoradiotherapy; proteomics; rectal cancer
0.572
67
Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology
2,023
35,997,003
The comparison of two different mandibular positions for oral appliance therapy in patients with obstructive sleep apnea.
Clinical and experimental dental research
Clin Exp Dent Res
8
6
10.1002/cre2.650
eng
2,022
12
null
2,022
8
23
[BACKGROUND] An oral appliance (OA) can alleviate upper airway obstruction by pulling the mandible forward during sleep. While a large mandibular advancement with an OA decreases the number of apnea and hypopnea events, long-term use may cause side effects, such as toothache, stiffness, and pain in the temporomandibula...
mandibular position; obstructive sleep apnea; oral appliance; treatment effectiveness
0.481
27
Dentistry
Dentistry
2,022
35,996,319
Valuing home modifications: The street-level policy work of occupational therapists in Australian home modification practice.
Australian occupational therapy journal
Aust Occup Ther J
70
1
10.1111/1440-1630.12836
eng
2,023
2
null
2,022
8
22
[INTRODUCTION] Occupational therapists recommending home modifications in Australia are often required by funding bodies to consider 'value' and 'value for money' (VFM); however, clear guidance on how to define and apply these concepts is not always provided. This paper reports on a qualitative study examining how the ...
ageing; disability; health; home modification; occupational therapy; value; value for money
0.491
56
Occupational Therapy
Health Professions
2,023
35,996,253
Cancer Drug Resistance Reduction via Co-treatment with Oxaliplatin and Nitazoxanide: Targeting the ABC Transporters.
Current molecular medicine
Curr Mol Med
23
8
10.2174/1566524023666220820154623
eng
2,023
null
null
null
null
null
[OBJECTS] Shortly after cancer is diagnosed, a phenomenon develops in cancer cells called multidrug resistance (MDR), in which cell sensitivity against anti-cancer drugs is significantly reduced. The present investigation aimed to assess the effects of nitazoxanide (NTZ), a safe drug, on LS174T/OXP-resistant cells. [ME...
ABC transporters; ATP-binding cassette; Colorectal cancer; multidrug resistance; nitazoxanide; oxaliplatin
null
null
null
null
null
35,996,215
Dual division of focal plane polarimeters-based collinear reflection Mueller matrix fast imaging microscope.
Journal of biomedical optics
J Biomed Opt
27
8
10.1117/1.JBO.27.8.086501
eng
2,022
8
null
null
null
null
[SIGNIFICANCE] Reflection Mueller matrix imaging is suitable for characterizing the microstructure of bulk specimens and probing dynamic processes in living animals, there are always demands for speed and accuracy for such applications to avoid possible artifacts and reveal a sample's intrinsic properties. [AIM] To dem...
DoFP polarimeter; Mueller matrix; dynamic process; microscope; polarization
0.824
165
Atomic and Molecular Physics, and Optics; Electronic, Optical and Magnetic Materials; Biomaterials; Biomedical Engineering
Engineering; Materials Science; Physics and Astronomy
2,022
35,996,189
Plasmodium relictum infection in Culex quinquefasciatus (Culicidae) decreases diel flight activity but increases peak dusk flight activity.
Malaria journal
Malar J
21
1
10.1186/s12936-022-04265-9
eng
2,022
8
22
2,022
8
22
[BACKGROUND] Parasites are recognized for their ability to modify host physiology and behaviours in ways that increase parasite fitness. Protozoan parasites of the genus Plasmodium are a group of widespread vector-borne parasites of vertebrates, causing disease to a wide range of hosts, but most notably to human and av...
null
1.237
126
Infectious Diseases; Parasitology
Immunology and Microbiology; Medicine
2,022
35,996,170
A novel signature to predict thyroid cancer prognosis and immune landscape using immune-related LncRNA pairs.
BMC medical genomics
BMC Med Genomics
15
1
10.1186/s12920-022-01332-7
eng
2,022
8
22
2,022
8
22
[BACKGROUND] Thyroid cancer (TC) is the most common endocrine malignancy worldwide. The incidence of TC is high and increasing worldwide due to continuous improvements in diagnostic technology. Therefore, identifying accurate prognostic predictions to stratify TC patients is important. [METHODS] Raw data were downloade...
Immune checkpoint inhibitors; Immune infiltration; TCGA; Thyroid carcinoma; lncRNA pairs
0.892
99
Genetics; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,996,144
Retrospective analysis of deformed complex vertebral osteotomy in children with severe thoracic post-tubercular angular kyphosis.
BMC musculoskeletal disorders
BMC Musculoskelet Disord
23
1
10.1186/s12891-022-05756-1
eng
2,022
8
23
2,022
8
23
[BACKGROUND] Many surgical options have been described to manage post-tubercular kyphosis, but the standard approach for treating severe post-tubercular angular kyphosis in children has not been established yet. The present study was performed to evaluate the safety and efficacy of deformed complex vertebral osteotomy ...
Angular kyphosis; Children; Deformed complex vertebrae; Post-tubercular; Wedge osteotomy
0.716
131
Orthopedics and Sports Medicine; Rheumatology
Medicine
2,022
35,996,063
Synthetic graft for medial patellofemoral ligament reconstruction: a systematic review.
Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology
J Orthop Traumatol
23
1
10.1186/s10195-022-00660-9
eng
2,022
8
22
2,022
8
22
[BACKGROUND] This systematic review investigates the role of synthetic graft for primary medial patellofemoral ligament (MPFL) reconstruction in patients with recurrent patellofemoral instability, focusing on clinical scores and the rate of complications. [METHODS] This systematic review was conducted according to the ...
MPFL; Patellofemoral instability; Synthetic graft
0.941
55
Medicine; Orthopedics and Sports Medicine; Surgery
Medicine
2,022
35,995,725
Multiparametric flow cytometry directing the evaluation of CRLF2 rearrangements and JAK2 status in pediatric B cell precursor acute lymphoblastic leukemia.
Hematology, transfusion and cell therapy
Hematol Transfus Cell Ther
45
2
10.1016/j.htct.2022.06.008
eng
2,023
null
null
2,022
8
5
[INTRODUCTION] This study aimed to determine whether cytokine receptor-like factor 2 (CRLF2) antigen expression evaluated using multiparametric flow cytometry (MFC) could predict the genotype of CRLF2 and Janus kinase 2 (JAK2) status for application in the diagnosis of pediatric B-cell precursor acute lymphoblastic leu...
B-other ALL; CRLF2 rearrangements; Cytogenetic molecular alterations; Immunophenotyping
0.376
33
Hematology; Immunology and Allergy
Medicine
2,023
35,994,324
Sociotechnical Intervention for Improved Delivery of Preventive Cardiovascular Care to Rural Communities: Participatory Design Approach.
Journal of medical Internet research
J Med Internet Res
24
8
10.2196/27333
eng
2,022
8
22
2,022
8
22
[BACKGROUND] Clinical practice guidelines recommend antiplatelet and statin therapies as well as blood pressure control and tobacco cessation for secondary prevention in patients with established atherosclerotic cardiovascular diseases (ASCVDs). However, these strategies for risk modification are underused, especially ...
atherosclerotic cardiovascular diseases; community health; participatory design; rural health; secondary prevention; sociotechnical; team-based care
1.992
214
Health Informatics
Medicine
2,022
35,994,321
Feasibility and Acceptability of an Active Video Game-Based Physical Activity Support Group (Pink Warrior) for Survivors of Breast Cancer: Randomized Controlled Pilot Trial.
JMIR cancer
JMIR Cancer
8
3
10.2196/36889
eng
2,022
8
22
2,022
8
22
[BACKGROUND] Survivors of breast cancer with functional limitations have a 40% higher mortality rate than those without. Despite the known benefits of physical activity (PA), 40% of survivors of breast cancer meet the recommendations for PA. The combination of active video games (AVGs) and group-based PA counseling may...
breast cancer; group intervention; mobile phone; motivation; physical activity; physical function; pilot study; survivors of cancer; video games
0.724
28
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,994,029
The Effect of a Dedicated Lung Mass Clinic on Lung Nodule Follow Up.
Annals of public health epidemiology
Ann Public Health Epidemiol
1
5
10.33552/aphe.2022.01.000524
eng
2,022
null
null
2,022
5
9
[INTRODUCTION] With the increased use of computed tomography (CT) imaging, lung nodules are found yearly requiring tracking and guideline directed follow up imaging. We describe the structure of a clinic dedicated to lung nodule tracking, patient education and the outcomes of lung nodule follow up. [METHODS] Patient el...
null
null
null
null
null
null
35,993,665
Development of a real-time in vivo dosimetry tool for electron beam therapy using a flexible thin film solar cell coated with scintillator powder.
Medical physics
Med Phys
50
1
10.1002/mp.15947
eng
2,023
1
null
2,022
9
4
[PURPOSE] A real-time solar cell based in vivo dosimetry system (SC-IVD) was developed using a flexible thin film solar cell and scintillating powder. The present study evaluated the clinical feasibility of the SC-IVD in electron beam therapy. [METHODS] A thin film solar cell was coated with 100 mg of scintillating pow...
electron beam therapy; flexible thin film solar cell; in vivo dosimetry; real-time measurement
1.052
218
Biophysics; Medicine; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
35,993,654
The novel biomarker, neopterin, can predict the severity of COVID-19.
European review for medical and pharmacological sciences
Eur Rev Med Pharmacol Sci
26
15
10.26355/eurrev_202208_29428
eng
2,022
8
null
null
null
null
[OBJECTIVE] SARS-CoV-2 infection primarily affects T-lymphocytes, particularly CD4+ and CD8+ T cells. However, there is a need for simpler and less expensive laboratory tests with predictive values comparable to CD4+ cell counts. Thus, the goal of this study was to investigate the role of neopterin levels in predicting...
null
null
null
null
null
null
35,993,651
Short-term efficacy and safety of edoxaban for venous thromboembolism after total hip or knee arthroplasty: a systematic review and meta-analysis.
European review for medical and pharmacological sciences
Eur Rev Med Pharmacol Sci
26
15
10.26355/eurrev_202208_29425
eng
2,022
8
null
null
null
null
[OBJECTIVE] Previous preliminary clinical trials have confirmed that edoxaban can be efficacious for venous thromboembolism (VTE). This meta-analysis was considered to evaluate edoxaban's short-term efficacy and safety for venous thromboembolism after arthroplasty. [MATERIALS AND METHODS] A comprehensive search was per...
null
null
null
null
null
null
35,993,500
Development of an Index to Assess COVID-19 Hospital Care Installed Capacity in the 450 Brazilian Health Regions.
Disaster medicine and public health preparedness
Disaster Med Public Health Prep
17
null
10.1017/dmp.2022.214
eng
2,022
8
22
2,022
8
22
[OBJECTIVE] The article seeks to assess the Brazilian health system ability to respond to the challenges imposed by the coronavirus disease 2019 (COVID-19) pandemic by measuring the capacity of Brazilian hospitals to care for COVID-19 cases in the 450 Health Regions of the country during the year 2020. Hospital capacit...
COVID-19; hospital capacity; regionalization of health
0.586
60
Public Health, Environmental and Occupational Health
Medicine
2,022
35,993,462
A Weakly Supervised Brain Tumor Segmentation Strategy Based on Multi-level Sub-category and Membership Matrix.
Current medical imaging
Curr Med Imaging
19
10
10.2174/1573405618666220820112145
eng
2,023
null
null
null
null
null
[BACKGROUND] Using a classification network to generate class activation mapping (CAM) is a mainstream method for weakly supervised semantic segmentation. However, for brain tumor images, CAM cannot fit the boundary of the tumor well. [OBJECTIVE] To improve the performance of brain tumor CAM, we propose a weakly superv...
Weakly supervised segmentation; boundary exploration; medical imaging; membership matrix supervision; multi-level sub-category; tumor
0.288
27
Internal Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,023
35,993,435
The Social and Psychological Impact of Acne Treatment: A Cross-Sectional Study of Blood Donors.
Journal of cutaneous medicine and surgery
J Cutan Med Surg
26
5
10.1177/12034754221119496
eng
2,022
null
null
2,022
8
21
[BACKGROUND] Acne in adolescence and adulthood is believed to have a long-term impact on socioeconomic status (SES) and health-related quality-of-life (HRQoL) in adults. [OBJECTIVE] To estimate the cross-sectional prevalence of medically treated (MedTreAc) and untreated acne (UnTreAc) and to characterize its long-term ...
SF-12; acne vulgaris; depression; income; quality of life; salaries; socioeconomic factors
0.673
58
Dermatology; Surgery
Medicine
2,022
35,993,236
Risk of Myocarditis After Sequential Doses of COVID-19 Vaccine and SARS-CoV-2 Infection by Age and Sex.
Circulation
Circulation
146
10
10.1161/CIRCULATIONAHA.122.059970
eng
2,022
9
6
2,022
8
22
[BACKGROUND] Myocarditis is more common after severe acute respiratory syndrome coronavirus 2 infection than after COVID-19 vaccination, but the risks in younger people and after sequential vaccine doses are less certain. [METHODS] A self-controlled case series study of people ages 13 years or older vaccinated for COVI...
2019-nCoV vaccine mRNA-1273; BNT162 vaccine; COVID-19; COVID-19 vaccines; ChAdOx1 nCoV-19; SARS-CoV-2; myocarditis
7.8
691
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,022
35,993,094
Accuracy of GenoQuick MTB test in detection of Mycobacterium tuberculosis in sputum from TB presumptive patients in Uganda.
SAGE open medicine
SAGE Open Med
10
null
10.1177/20503121221116861
eng
2,022
null
null
2,022
8
16
[OBJECTIVE] The objective of the study was to determine the diagnostic performance of the GenoQuick MTB test on heated sputum against the conventional Lowenstein-Jensen Mycobacterium tuberculosis culture as the reference method for tuberculosis diagnosis. [INTRODUCTION] Fast, reliable, and easy-to-use tests for tubercu...
Diagnosis; GenoQuick MTB; Mycobacterium tuberculosis; and resource-limited settings; diagnostic accuracy; nucleic acid amplification
0.613
41
Medicine
Medicine
2,022
35,993,062
Effects of farrowing induction using cloprostenol on sow farrowing characteristics.
Veterinary world
Vet World
15
6
10.14202/vetworld.2022.1535-1540
eng
2,022
6
null
2,022
6
25
[BACKGROUND AND AIM] Previous findings regarding the effects of farrowing induction on the farrowing characteristics of sows are controversial. This study aimed to investigate the effects of farrowing induction on the following characteristics: (1) Proportion of sows that farrowed during working hours, (2) stillbirth r...
birth interval; cloprostenol; dystocia; stillbirth
0.433
56
Veterinary
Veterinary
2,022
35,993,015
Exploring the educational needs of patients with systemic vasculitis using the educational needs assessment tool.
Rheumatology advances in practice
Rheumatol Adv Pract
6
2
10.1093/rap/rkac062
eng
2,022
null
null
2,022
8
11
[OBJECTIVES] Knowledge and health literacy enable patients to monitor symptoms and disease impact. Educational needs have previously been explored in rheumatology, but scarcely for patients with ANCA-associated vasculitis (AAV). The aim of the study was to assess the educational needs among patients with AAV using the ...
ANCA-associated vasculitis; educational needs; health literacy; nursing; outcome measures; patient experience
0.806
20
Rheumatology
Medicine
2,022
35,992,977
Artelon as a Bio-Scaffold to Augment Collateral Ligament Repair after Knee Dislocation.
Malaysian orthopaedic journal
Malays Orthop J
16
2
10.5704/MOJ.2207.014
eng
2,022
7
null
null
null
null
[INTRODUCTION] Knee dislocations (KD) have high rates of multi-ligamentous injury (MLI). Collateral ligaments rupture in 50-60% of KDs. Traditionally, collateral ligaments have undergone primary repair, though microscopic healing is not optimal. Artelon is a degradable, polyurethane urea bio-scaffold thought to decreas...
artelon; bioaugmentation; graft; knee dislocation; multiligamentous knee disruption
null
null
null
null
null
35,992,880
Development of 3-dimensional printed simulation surgical training models for endoscopic endonasal and transorbital surgery.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.966051
eng
2,022
null
null
2,022
8
5
[BACKGROUND] Endoscopic skull base surgery (ESBS) is complex, requiring methodical and unremitting surgical training. Herein, we describe the development and evaluation of a novel three-dimensional (3D) printed simulation model for ESBS. We further validate the efficacy of this model as educational support in neurosurg...
3-dimensional printed simulation; endoscopic endonasal approach; endoscopic skull base surgery; endoscopic transorbital approach; surgical simulation
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,992,876
An exploratory study on the checkout rate of circulating tumor cells and the prediction of efficacy of neoadjuvant therapy and prognosis in patients with HER-2-positive early breast cancer.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.966624
eng
2,022
null
null
2,022
8
4
[BACKGROUND] Neoadjuvant therapy is a standard treatment for patients with large, nonmetastatic breast cancer and may allow breast-conserving surgery after tumor downsizing while decreasing the risk of subsequent relapse. Dynamic changes of circulation tumor cells (CTCs) have a role in predicting treatment efficacy of ...
HER-2-positive early breast cancer; breast cancer; circulating tumor cells (CTCs); liquid biopsy; neoadjuvant therapy; prognostic
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,992,813
Combination of [18]F-FDG PET/CT and convex probe endobronchial ultrasound elastography for intrathoracic malignant and benign lymph nodes prediction.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.908265
eng
2,022
null
null
2,022
8
5
[BACKGROUND] Positron emission tomography-computed tomography (PET/CT) and convex probe endobronchial ultrasound (CP-EBUS) elastography are important diagnostic methods in predicting intrathoracic lymph nodes (LNs) metastasis, but a joint analysis of the two examinations is still lacking. This study aimed to compare th...
PET/CT; diagnosis; elastography; endobronchial ultrasound; lymph nodes
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
35,992,052
Use of Eggshells as Bone Grafts around Commercially Pure Titanium Implant Screws Coated with Nano Calcium Sulfate.
International journal of biomaterials
Int J Biomater
2022
null
10.1155/2022/8722283
eng
2,022
null
null
2,022
8
10
[BACKGROUND] Implant insertion in regions with poor bone quantity, such as the posterior maxilla, is potentially associated with an increased rate of implant failure. Calcium sulfate can be used as the coating material for commercially pure titanium (CpTi) and as the bone graft material around implants when bound to eg...
null
null
null
null
null
null
36,003,177
Multimodal image analysis and subvalvular dynamics in ischemic mitral regurgitation.
JTCVS open
JTCVS Open
5
null
10.1016/j.xjon.2020.10.007
eng
2,021
3
null
2,020
10
30
[BACKGROUND] The exact geometric pathogenesis of leaflet tethering in ischemic mitral regurgitation (IMR) and the relative contribution of each component of the mitral valve complex (MVC) remain largely unknown. In this study, we sought to further elucidate mitral valve (MV) leaflet remodeling and papillary muscle dyna...
2D, two-dimensional; 3D echocardiography; 3DE, 3-dimensional echocardiography; AC, anterior commissure; ALPM, anterolateral papillary muscle; ANC, annular center; BNM, bilateral noncongruent movement; IMR, ischemic mitral regurgitation; LV, left ventricular; MI, myocardial infarction; MV, mitral valve; MVC, mitral valv...
null
15
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,021
36,004,299
Functional tricuspid valve insufficiency after cardiac transplantation: Which factor is the most important?
JTCVS open
JTCVS Open
4
null
10.1016/j.xjon.2020.07.008
eng
2,020
12
null
2,020
8
3
[OBJECTIVES] Tricuspid insufficiency (TI) is the most common valvular complication following orthotopic heart transplantation (HTx) and in serious cases is associated with increased mortality. In this study, we analyze the possible variables influencing TI following HTx and aim to identify the most important risk facto...
BMI, body mass index; BSA, body surface area; EMB, endomyocardial biopsy; HTx, heart transplantation (orthotopic); TI, tricuspid insufficiency; cardiac transplantation; myokardial biopsy; operative technique of cardiac transplantation; right atrial geometry; tricuspid valve insufficiency
null
15
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,020
36,003,874
Computer simulations of transapical mitral valve repair with neochordae implantation: Clinical implications.
JTCVS open
JTCVS Open
3
null
10.1016/j.xjon.2020.05.010
eng
2,020
9
null
2,020
6
6
[OBJECTIVES] Transapical beating heart neochordae implantation is an innovative mitral valve repair technique that has demonstrated promising clinical results in patients with primary mitral regurgitation. However, as clinical experience continues to increase, neochordae implantation criteria have not been fully standa...
AL-NC, antero-lateral neochordae; AML, anterior mitral leaflet; AV, aortic valve; FSI, fluid-structure interaction; LV, left ventricle; MR, mitral regurgitation; MV, mitral valve; NC, neochordae; PL-NC, postero-lateral neochordae; PM, papillary muscle; PML, posterior mitral leaflet; beating heart mitral valve repair; e...
null
15
Cardiology and Cardiovascular Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,020
36,058,775
The Profiles of Laryngopharyngeal Reflux in Patients With Different Vocal Fold Lesions.
Journal of voice : official journal of the Voice Foundation
J Voice
39
1
10.1016/j.jvoice.2022.08.002
eng
2,025
1
null
2,022
9
2
[OBJECTIVES] To investigate the profiles of laryngopharyngeal reflux (LPR) and the relationship between hypopharyngeal-proximal reflux episodes (HREs) and the positive rate of salivary pepsin testing in patients with vocal fold lesions (VFLs). [METHODS] The enrolled patients were divided into vocal fold cancer group (V...
Laryngopharyngeal reflux; Pepsin; Profiles; Vocal fold lesions
0.573
114
LPN and LVN; Otorhinolaryngology; Speech and Hearing
Health Professions; Medicine; Nursing
2,024
36,058,630
Young bone marrow transplantation prevents aging-related muscle atrophy in a senescence-accelerated mouse prone 10 model.
Journal of cachexia, sarcopenia and muscle
J Cachexia Sarcopenia Muscle
13
6
10.1002/jcsm.13058
eng
2,022
12
null
2,022
9
4
[BACKGROUND] Young bone marrow transplantation (YBMT) has been shown to stimulate vascular regeneration in pathological conditions, including ageing. Here, we investigated the benefits and mechanisms of the preventive effects of YBMT on loss of muscle mass and function in a senescence-associated mouse prone 10 (SAMP10)...
Aging; Bone marrow transplantation; Mouse model; Muscle stem cell; SAMP10; Sarcopenia
2.159
112
Orthopedics and Sports Medicine; Physiology
Medicine
2,022
36,058,514
Improving Adherence in Urban Youth With Asthma: Role of Community Health Workers.
The journal of allergy and clinical immunology. In practice
J Allergy Clin Immunol Pract
10
12
10.1016/j.jaip.2022.08.030
eng
2,022
12
null
2,022
9
1
[BACKGROUND] The Asthma Action at Erie Trial is a comparative effectiveness trial comparing a community health worker (CHW) versus certified asthma educator (AE-C) intervention in low-income minority children. [OBJECTIVES] Determine whether asthma medication possession, adherence, technique, and triggers differ in chil...
Asthma; Behavioral clinical trial; Certified asthma educators; Community health workers; Patient navigators; Pediatrics
null
null
null
null
null
36,058,164
Clinical outcomes of digital health in adults with cystic fibrosis.
Respiratory medicine
Respir Med
202
null
10.1016/j.rmed.2022.106970
eng
2,022
10
null
2,022
8
28
[BACKGROUND] The aim of this study was to assess the long-term clinical impact of the application of e-health as part of a virtual model of care in patients with Cystic Fibrosis (CF). [METHODS] Digital care group (DCG) were deemed suitable for using the NuvoAir Home platform to monitor their disease at home as part of ...
Cystic fibrosis; Digital health; Longer-term telehealth benefits; Virtual monitoring
1.334
145
Pulmonary and Respiratory Medicine
Medicine
2,022
36,057,944
A comprehensive quality assurance procedure for 4D CT commissioning and periodic QA.
Journal of applied clinical medical physics
J Appl Clin Med Phys
23
11
10.1002/acm2.13764
eng
2,022
11
null
2,022
9
4
[PURPOSE] The 4D computed tomography (CT) simulation is an essential procedure for tumors exhibiting breathing-induced motion. However, to date there are no established guidelines to assess the characteristics of existing systems and to describe meaningful performance. We propose a commissioning quality assurance (QA) ...
4D CT; CT simulation; quality assurance; radiotherapy; respiratory motion-management
0.629
64
Radiation; Instrumentation; Medicine; Radiology, Nuclear Medicine and Imaging
Medicine; Physics and Astronomy
2,022
36,057,756
From Weight Bias Internalization to Health-Related Quality of Life: Self-esteem and Psychopathology in Pre-bariatric Surgery Patients.
Obesity surgery
Obes Surg
32
11
10.1007/s11695-022-06261-z
eng
2,022
11
null
2,022
9
3
[INTRODUCTION] It has been reported that people seeking bariatric surgery have poor health-related quality of life (HRQoL). Weight bias internalization (WBI) is prevalent in this population and strongly associated with psychopathology and health status. However, the psychological mechanisms underlying the relationship ...
Bariatric surgery; Health-related quality of life; Psychopathology; Self-esteem; Weight bias internalization
1.127
164
Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics; Surgery
Medicine; Nursing
2,022
36,057,522
Treatment of Ph-Negative Acute Lymphoblastic Leukemia in Adolescents and Young Adults with an Affordable Outpatient Pediatric Regimen.
Clinical lymphoma, myeloma leukemia
Clin Lymphoma Myeloma Leuk
22
12
10.1016/j.clml.2022.07.014
eng
2,022
12
null
2,022
8
1
[BACKGROUND] B-cell acute lymphoblastic leukemia is frequent in Hispanic adolescents and young adults. Outcomes of implementation of pediatric-inspired regimens in low-and middle-income countries are not well known. [METHODS] In this study we treated 94 adolescents and young adults with a local BFM regimen designed to ...
Ambulatory; Chemotherapy; Low-middle income country; Pediatric regimens; Treatment abandonment
null
null
null
null
null
36,057,423
Frequency of genotypic factors possibly associated with cabotegravir/rilpivirine failure in antiretroviral treatment-naïve and -experienced HIV-1- infected population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Infect Genet Evol
104
null
10.1016/j.meegid.2022.105358
eng
2,022
10
null
2,022
8
31
[OBJECTIVES] The long-acting injectable (LAI) cabotegravir (CAB) and rilpivirine (RPV) treatment offers important advantages over oral ART (antiretroviral therapy), however baseline factors possibly contributing to the CAB/RPV treatment failure were identified. The purpose of this study was to describe the frequency of...
Cabotegravir; HIV-1; Mutation; Resistance; Rilpivirine; Subtype A1/A6
0.826
118
Ecology, Evolution, Behavior and Systematics; Genetics; Infectious Diseases; Microbiology; Microbiology; Molecular Biology
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,022
36,057,246
Abdominal cocoon syndrome as rare cause of intestinal obstruction: A case report.
International journal of surgery case reports
Int J Surg Case Rep
98
null
10.1016/j.ijscr.2022.107547
eng
2,022
9
null
2,022
8
24
[INTRODUCTION] Abdominal cocoon syndrome (ACS) is a rare complication that is hardly diagnosed before surgery. Abnormal membrane in partial or total intestine can make obstruction with generalized abdomen pain. [CASE PRESENTATION] We present a case of 43-year-old man, who presented to our hospital with generalized abdo...
Abdominal cocoon syndrome; Case report; Obstruction; Surgery
0.193
31
Surgery
Medicine
2,022
36,057,143
Integration of pharmacodynamics and metabolomics reveals the therapeutic effects of 6-acetylacteoside on ovariectomy-induced osteoporosis mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Phytomedicine
106
null
10.1016/j.phymed.2022.154399
eng
2,022
11
null
2,022
8
27
[BACKGROUND] 6-acetylacteoside (6-AA) is a phenylethanoid glycoside isolated from Cistanche deserticola which had been previously proven to possess anti-osteoporotic activity previously. Currently, it is still unknown whether 6-AA plays a crucial role on the anti-osteoporotic effects of C. deserticola. [PURPOSE] To elu...
6-acetylacteoside; Bone osteoporosis; Metabolomics; Ovariectomized mice; RANKL/RANK/OPG
1.126
150
Complementary and Alternative Medicine; Drug Discovery; Pharmaceutical Science; Pharmacology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,057,130
Assessment of acute and chronic toxicity of cyantraniliprole and sulfoxaflor on honey bee (Apis mellifera) larvae.
Pest management science
Pest Manag Sci
78
12
10.1002/ps.7162
eng
2,022
12
null
2,022
9
17
[BACKGROUND] Recently, cyantraniliprole (CYA) and sulfoxaflor (SUL) have been considered as alternatives to neonicotinoid insecticides. In this study, we evaluated the acute and chronic toxicities of CYA and SUL on honey bee (Apis mellifera L.) larvae reared in vitro. [RESULTS] In the acute toxicity test, the following...
Cyantraniliprole; honey bee larvae; sulfoxaflor; toxicity assessment
null
null
null
null
null
36,056,887
Impact of secondary mitral valve chordal cutting on valve geometry in obstructive hypertrophic cardiomyopathy with marked septal hypertrophy.
European heart journal. Cardiovascular Imaging
Eur Heart J Cardiovasc Imaging
24
5
10.1093/ehjci/jeac179
eng
2,023
4
24
null
null
null
[AIMS] In patients with obstructive hypertrophic cardiomyopathy (HCM) and mild septal thickness undergoing myectomy, resecting fibrotic anterior mitral leaflet (AML) secondary chordae moves the mitral valve (MV) away from the outflow tract and ejection flow, reducing the need for a deep septal excision. Aim of the pres...
chordal cutting; hypertrophic cardiomyopathy; septal myectomy
null
null
null
null
null
36,056,859
Tannic Acid, as a Structural Moiety Coupled to a Protein Antigen, Exhibiting a Molecular-structure Adjuvant Activity for Antibody Specificity Enhancement.
Protein and peptide letters
Protein Pept Lett
29
11
10.2174/0929866529666220902152147
eng
2,022
null
null
null
null
null
[BACKGROUND] An antigen is a small foreign substance, such as a microorganism structural protein, that may trigger an immune response once inside the body. Antigens are preferentially used rather than completely attenuated microorganisms to develop safe vaccines. Unfortunately, not all antigens are able to induce an im...
Adjuvant; cell-mediated immunity; humoral immunity; immunogenicity; tannic acid; vaccine adjuvant
null
null
null
null
null
36,056,852
miRNA-1260b Promotes Breast Cancer Cell Migration and Invasion by Downregulating CCDC134.
Current gene therapy
Curr Gene Ther
23
1
10.2174/1566523222666220901112314
eng
2,023
null
null
null
null
null
[BACKGROUND] Breast cancer (BRCA) is the most common type of cancer among women worldwide. MiR-1260b has been widely demonstrated to participate in multiple crucial biological functions of cancer tumorigenesis, but its functional effect and mechanism in human breast cancer have not been fully understood. [METHODS] qRT-...
Breast cancer; CCDC134; MAPK signaling pathways; cancer cell; miR-1260b; tumor
null
null
null
null
null
36,056,757
Metagenomic analysis of the fecal microbiome in colorectal cancer patients compared to healthy controls as a function of age.
Cancer medicine
Cancer Med
12
3
10.1002/cam4.5197
eng
2,023
2
null
2,022
9
3
[BACKGROUND AND AIMS] Colorectal cancer (CRC) incidence is increasing in young patients without a clear etiology. Emerging data have implicated the fecal microbiome in CRC carcinogenesis. However, its impact on young onset CRC is poorly defined. [METHODS] We performed a meta-analysis of fecal metagenomics sequencing da...
Fusobacterium nucleatum, colibactin; young-onset colorectal cancer
1.174
95
Oncology; Radiology, Nuclear Medicine and Imaging; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,056,709
Elevated gamma-glutamyl transferase to high-density lipoprotein cholesterol ratio has a non-linear association with incident diabetes mellitus: A second analysis of a cohort study.
Journal of diabetes investigation
J Diabetes Investig
13
12
10.1111/jdi.13900
eng
2,022
12
null
2,022
9
3
[OBJECTIVE] Evidence regarding the association between the GGT/HDL-c ratio and incident diabetes is still limited. On that account, our research aims to survey the link of the GGT/HDL-c ratio with the risk of diabetes. [METHODS] In this retrospective cohort study, data of 15,171 participants who participated in the med...
Cox proportional-hazards regression model; Diabetes
0.992
75
Medicine; Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,022
36,056,273
Associated factors on physical activity among childhood cancer survivors in Mainland China: a qualitative exploration applied health belief model.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
30
11
10.1007/s00520-022-07324-8
eng
2,022
11
null
2,022
9
3
[PURPOSE] Regular physical activity (PA) is essential for childhood cancer survivors (CCS), yet most CCS have difficulty participating in it. The level of PA participation among CCS in China is lower than those of western countries, leading to a worse long-term survival of CCS in China. Here, the study aims to explore ...
Childhood cancer survivors (CCS); Health belief model (HBM); Physical activity (PA); Qualitative analysis
0.984
143
Oncology
Medicine
2,022
36,056,169
Oncological and functional outcomes of transoral laser surgery for hypopharyngeal carcinoma.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Eur Arch Otorhinolaryngol
280
2
10.1007/s00405-022-07622-1
eng
2,023
2
null
2,022
9
3
[BACKGROUND] Surgical resection or radiotherapy (RT) are standard approaches for early-staged hypopharyngeal squamous cell carcinoma (HPSCC). Transoral laser microsurgery (TOLMS) seems to provide good oncological and functional results with few local complications. The aim of our study was to analyze the outcomes of TO...
Head and neck cancer; Hypopharyngeal cancer; Laser; Surgery; Transoral
0.792
94
Otorhinolaryngology; Medicine
Medicine
2,023
36,055,935
Sleep health among U.S. Hispanic/Latinx children: An examination of correlates of meeting sleep duration recommendations.
Sleep health
Sleep Health
8
6
10.1016/j.sleh.2022.07.002
eng
2,022
12
null
2,022
8
30
[OBJECTIVES] The objective of this study was to examine the association between sociodemographic, behavioral, and environmental factors and adherence to sleep duration recommendations among 1165 U.S. Hispanic/Latinx children. [METHODS] In this cross-sectional study, the following parent-reported variables were examined...
Hispanic/Latino children; Racial/ethnic disparities; Sleep duration; Sleep health
1.16
51
Behavioral Neuroscience; Health; Neuropsychology and Physiological Psychology; Social Sciences
Neuroscience; Psychology; Social Sciences
2,022
36,055,283
Race/Ethnicity and Perception of Care: Does Patient-Provider Concordance Matter?
American journal of perinatology
Am J Perinatol
41
S 01
10.1055/s-0042-1755548
eng
2,024
5
null
2,022
9
2
[OBJECTIVE] We determine whether racial concordance between postpartum patients and obstetric providers (dyads) impacts the perception of quality of care among people undergoing intrapartum obstetrical procedures. [STUDY DESIGN] This is a prospective cohort study of postpartum people who underwent operative vaginal or ...
null
0.713
87
Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine
2,024
36,055,087
WDR5 drives the development of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition and cancer-associated fibroblasts formation.
Pathology, research and practice
Pathol Res Pract
238
null
10.1016/j.prp.2022.154076
eng
2,022
10
null
2,022
8
17
[BACKGROUND] WD repeat domain 5 (WDR5) has been indicated to be involved in tumor progression, however, its role in cervical cancer (CC) has not been investigated yet. [METHODS] A total of 350 pairs of CC tissues and para-carcinoma tissues (PCT) were collected. Primary human cervical epithelial cells (hCECs) and cancer...
C-X-C motif chemokine ligand 8; Cancer-associated fibroblasts; Cervical squamous cell carcinoma; Epithelial-mesenchymal transition; WD repeat domain 5
0.652
72
Pathology and Forensic Medicine; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,054,491
Prevalence and outcome of lymphopenia in the Paediatric Intensive Care Unit: A prospective observational study.
Journal of paediatrics and child health
J Paediatr Child Health
58
12
10.1111/jpc.16183
eng
2,022
12
null
2,022
8
20
[AIM] Leukopenia (lymphopenia or neutropenia) may be an important marker of altered immunity and risk in children with critical illness. We aimed to evaluate the prevalence, course, and outcome of leukopenia in children admitted to Paediatric Intensive Care Unit (PICU). [METHODS] All consecutive children (n = 200) admi...
cardiopulmonary bypass; children; cytopenia; intensive care unit; lymphocytopenia
0.475
90
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,054,241
Craniofacial morphology in adults with osteogenesis imperfecta-A cross-sectional study.
Orthodontics craniofacial research
Orthod Craniofac Res
26
2
10.1111/ocr.12607
eng
2,023
5
null
2,022
9
8
[OBJECTIVES] The aim of this study was to compare the craniofacial and neurocranial morphology of adults with osteogenesis imperfecta (OI) with controls and to elucidate whether osseous origin impacts on morphological deviations in OI. [MATERIALS AND METHODS] Fifty-four adults (mean age 45.8) with OI type I, 14 adults ...
bone diseases; cephalometry; osteogenesis; regression analysis
null
null
null
null
null
36,054,168
Incident heart failure, arrhythmias and cardiovascular outcomes with sodium-glucose cotransporter 2 (SGLT2) inhibitor use in patients with diabetes: Insights from a global federated electronic medical record database.
Diabetes, obesity metabolism
Diabetes Obes Metab
25
2
10.1111/dom.14854
eng
2,023
2
null
2,022
9
27
[AIM] To investigate the impact of sodium-glucose cotransporter 2 (SGLT2) inhibitors on the risk of incident heart failure and adverse cardiovascular outcomes. [METHODS] All patients with diabetes who were registered between January 2018 and December 2019 were identified from a federated electronic medical record datab...
SGLT2 inhibitors; cardiovascular outcomes; diabetic; incident heart failure; prognosis
null
null
null
null
null
36,054,149
Clinical characteristics and 1-year outcomes in hospitalized patients with heart failure with preserved ejection fraction: results from the China Cardiovascular Association Database-Heart Failure Center Registry.
European journal of heart failure
Eur J Heart Fail
24
11
10.1002/ejhf.2654
eng
2,022
11
null
2,022
9
11
[AIM] We aimed to evaluate clinical characteristics and 1-year outcomes in hospitalized patients with heart failure with preserved ejection fraction (HFpEF) from China. Factors associated with outcomes (hospitalization for HF [HHF] and cardiovascular [CV] death) were assessed. [METHOD AND RESULTS] Data were from the Ch...
Epidemiology; Heart failure with preserved ejection fraction; Population study; Prognosis
null
null
null
null
null
36,054,033
Development and validation of prognostic nomograms in patients with ascending type of nasopharyngeal carcinoma: Retrospective study based on SEER database.
Head neck
Head Neck
44
12
10.1002/hed.27172
eng
2,022
12
null
2,022
8
20
[BACKGROUND] Nomograms specifically used to predict the prognosis of ascending type nasopharyngeal carcinoma (NPC) have not been constructed. [METHODS] Data of ascending type (T3-4N0-1M0) NPC from the Surveillance, Epidemiology, and End Results (SEER) database between 2004 and 2015 were extracted. [RESULTS] Altogether ...
ascending type; nasopharyngeal carcinoma; nomogram; prognosis; survival
null
null
null
null
null
36,053,938
Timing of initiation of renal replacement therapy for patients with acute kidney injury: A meta-analysis of RCTs.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
Ther Apher Dial
27
2
10.1111/1744-9987.13914
eng
2,023
4
null
2,022
8
30
[PURPOSE] To assess the effects of delayed versus early renal replacement therapy (RRT) initiation for patients with AKI. [METHODS] Related RCTs of RRT initiated at different times published on PubMed, Web of Science, Embase, and Cochrane Library were searched. [RESULTS] Fifteen RCTs studies with 5395 patients were inc...
initiation; meta-analysis; randomized controlled trials; renal replacement therapy
0.419
62
Hematology; Nephrology
Medicine
2,023
36,053,598
Universal language development screening: comparative performance of two questionnaires.
BMJ paediatrics open
BMJ Paediatr Open
6
1
10.1136/bmjpo-2021-001324
eng
2,022
1
null
null
null
null
[BACKGROUND AND OBJECTIVE] Low language ability in early childhood is a strong predictor of later psychopathology as well as reduced school readiness, lower educational attainment, employment problems and involvement with the criminal justice system. Assessment of early language development is universally offered in ma...
health services research
0.845
35
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,053,451
The cognitive functions and seizure outcomes of patients with low-grade epilepsy-associated neuroepithelial tumors.
Journal of neuro-oncology
J Neurooncol
160
1
10.1007/s11060-022-04076-7
eng
2,022
10
null
2,022
9
2
[PURPOSE] The aim of the study was to evaluate the cognitive functions and seizure outcomes of patients with low-grade epilepsy-associated neuroepithelial tumors (LEATs). [METHODS] We retrospectively reviewed the clinical data of patients who underwent preoperative neuropsychological evaluations and subsequent epilepsy...
Brain tumor; Cognition; Epilepsy; Risk factor; Seizure outcome; Surgery
1.178
141
Neurology; Neurology; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,022
36,053,369
Multiple-site decontamination regimen decreases acquired infection incidence in mechanically ventilated COVID-19 patients.
Annals of intensive care
Ann Intensive Care
12
1
10.1186/s13613-022-01057-x
eng
2,022
9
2
2,022
9
2
[BACKGROUND] Among strategies that aimed to prevent acquired infections (AIs), selective decontamination regimens have been poorly studied in the COVID-19 setting. We assessed the impact of a multiple-site decontamination (MSD) regimen on the incidence of bloodstream infections (BSI) and ventilator-associated pneumonia...
Bacteremia; COVID-19; Chlorhexidine; Critical care; Mortality; Mupirocin; Pneumonia; Selective digestive decontamination
2.616
85
Critical Care and Intensive Care Medicine
Medicine
2,022
36,053,286
Educational considerations based on medical student use of polygenic risk information and apparent race in a simulated consultation.
Genetics in medicine : official journal of the American College of Medical Genetics
Genet Med
24
11
10.1016/j.gim.2022.08.004
eng
2,022
11
null
2,022
9
2
[PURPOSE] To craft evidence-based educational approaches related to polygenic risk score (PRS) implementation, it is crucial to forecast issues and biases that may arise when PRS are introduced in clinical care. [METHODS] Medical students (N = 84) were randomized to a simulated primary care encounter with a Black or Wh...
Clinical simulation; Common disease; Health equity; Polygenic risk scores; Race
2.745
167
Genetics; Medicine
Medicine
2,022
36,053,063
Stage-dependent differential influence of metabolic and structural networks on memory across Alzheimer's disease continuum.
eLife
Elife
11
null
10.7554/eLife.77745
eng
2,022
9
2
2,022
9
2
[BACKGROUND] Large-scale neuronal network breakdown underlies memory impairment in Alzheimer's disease (AD). However, the differential trajectories of the relationships between network organisation and memory across pathology and cognitive stages in AD remain elusive. We determined whether and how the influences of ind...
Alzheimer's disease; amyloid; human; medicine; memory; metabolic network; mild cognitive impairment; neuroscience; structural network; tau
4.251
225
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Neuroscience
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Neuroscience
2,022
36,052,897
Efficacy of Intraoperative Low Dose Intravenous Amiodarone in Pharmacologic Cardioversion in Patients with Preoperative Atrial Fibrillation Presenting for Mitral Valve Replacement Surgery Randomized Control Trial.
The heart surgery forum
Heart Surg Forum
25
4
10.1532/hsf.4901
eng
2,022
7
27
2,022
7
27
[BACKGROUND] Atrial fibrillation (AF) is the most common form of dysrhythmia observed in the clinical field, causing multiple morbidities, such as thromboembolic complications. Hence, the maintenance of sinus rhythm is superior to rate control. This study tests the efficacy of single- and low-dose amiodarone on the per...
null
0.224
42
Surgery; Cardiology and Cardiovascular Medicine
Medicine
2,022
36,052,859
Psychomotor agitation and irritability in adolescents with manic episode: Clinical data from three inpatient units.
Clinical child psychology and psychiatry
Clin Child Psychol Psychiatry
28
4
10.1177/13591045221125331
eng
2,023
10
null
2,022
9
2
[OBJECTIVES] We aimed to investigate the characteristics of adolescents with Bipolar disorder-I with irritability and agitation (Mania+IA) compared to those without irritability and agitation (Mania-IA) in a multi-center representative sample. [METHODS] Data of 145 patients from three tertiary-care inpatient units betw...
bipolar disorder; childhood; irritability; mania; psychomotor agitation
0.808
67
Pediatrics, Perinatology and Child Health; Clinical Psychology; Medicine; Psychiatry and Mental Health
Medicine; Psychology
2,023
36,052,826
Development of PharmPAL: A Collaborative Practice Pharmacy Clinic in Ambulatory Palliative Care.
The American journal of hospice palliative care
Am J Hosp Palliat Care
40
5
10.1177/10499091221120593
eng
2,023
5
null
2,022
9
2
[BACKGROUND] Increased access to interprofessional palliative care is needed in ambulatory oncology settings. To achieve this, Dana-Farber Cancer Institute launched a collaborative drug therapy management clinic, PharmPAL, where credentialed advanced practice pharmacists lead independent patient visits. [METHODS] As pa...
Interprofessional; collaborative drug therapy management; collaborative practice; medication management; oncology; pharmacy
null
null
null
null
null
36,052,717
Gr1+ myeloid-derived suppressor cells participate in the regulation of lung-gut axis during mouse emphysema model.
Bioscience reports
Biosci Rep
42
9
10.1042/BSR20221041
eng
2,022
9
30
null
null
null
[BACKGROUND] Chronic obstructive pulmonary disease (COPD) is often accompanied by intestinal symptoms. Myeloid-derived suppressor cells (MDSCs) possess immunosuppressive ability in cancer, chronic inflammation, and infection. The aim of this study was to verify the distribution of MDSCs in emphysema mouse model and par...
COPD; Emphysema; MDSCs; lung-gut axis; macrophages
null
null
null
null
null
36,052,569
Ixazomib combined with lenalidomide and dexamethasone chemotherapy for newly diagnosed multiple myeloma in China-Compared with bortezomib/lenalidomide/dexamethasone.
Cancer medicine
Cancer Med
12
3
10.1002/cam4.5198
eng
2,023
2
null
2,022
9
2
[BACKGROUND] To compare the response and safety of Ixazomib/Lenalidomide/Dexamethasone (IRd) and Bortezomib/Lenalidomide/Dexamethasone (VRd) treatment in newly diagnosed multiple myeloma (MM). [METHODS] This was a single-center retrospective analysis in Xiangtan Central Hospital. A total of 52 newly diagnosed MM patien...
Ixazomib; adverse events; bortezomib; newly diagnosed multiple myeloma; real world
1.174
95
Oncology; Radiology, Nuclear Medicine and Imaging; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,052,273
The Association of IL7R rs6897932 with Risk of Multiple Sclerosis in Southern Chinese.
Neuropsychiatric disease and treatment
Neuropsychiatr Dis Treat
18
null
10.2147/NDT.S376066
eng
2,022
null
null
2,022
8
26
[OBJECTIVE] To investigate the association between IL7R rs6897932 and multiple sclerosis (MS) in southern Chinese people. [METHODS] In total, 147 MS patients and 530 healthy controls were recruited according to the revised McDonald criteria. The TaqMan method was used for genotyping. [RESULTS] With genetic models, we c...
IL7R; interleukin; multiple sclerosis; single-nucleotide polymorphism
0.789
98
Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience
2,022
36,052,100
Longitudinal changes in COVID-19 concern and stress: Pandemic fatigue overrides individual differences in caution.
Journal of public health research
J Public Health Res
11
3
10.1177/22799036221119011
eng
2,022
7
null
2,022
8
26
[BACKGROUND] Pandemic fatigue describes a phenomenon whereby individuals experience a decrease in COVID-19 concern over time, despite their risk for infection remaining stable, or even increasing. Individual differences in the experience of pandemic fatigue may have important implications for people's adherence to publ...
COVID fatigue; COVID-19; Pandemic fatigue; growth mixture modeling; latent class analysis
0.565
30
Public Health, Environmental and Occupational Health
Medicine
2,022