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36,087,118
Distraction osteogenesis at the proximal third of the ulna for the treatment of Masada type I/IIb deformities in children with hereditary multiple exostoses: a retrospective review of twenty cases.
International orthopaedics
Int Orthop
46
12
10.1007/s00264-022-05551-6
eng
2,022
12
null
2,022
9
10
[BACKGROUND] Ulna distraction by monolateral external fixator (MEFix) is a good option for the treatment of Masada type I and IIb deformities in children with hereditary multiple exostoses (HMEs). However, there is no consensus regarding where to perform ulnar osteotomy. Our hypothesis is that osteotomy at the proximal...
Forearm deformity; Hereditary multiple exostosis; Masada; Radial head dislocation; Ulnar lengthening
0.988
116
Orthopedics and Sports Medicine; Surgery
Medicine
2,022
36,086,752
Two novel predictive biomarkers for osteosarcoma and glycolysis pathways: A profiling study on HS2ST1 and SDC3.
Medicine
Medicine (Baltimore)
101
36
10.1097/MD.0000000000030192
eng
2,022
9
9
null
null
null
[INTRODUCTION] Prognostic biomarkers for osteosarcoma (OS) are still very few, and this study aims to examine 2 novel prognostic biomarkers for OS through combined bioinformatics and experimental approach. [MATERIALS AND METHODS] Expression profile data of OS and paraneoplastic tissues were downloaded from several onli...
null
null
null
null
null
null
36,085,413
Efficacy and safety of mirabegron for treatment of neurogenic detrusor overactivity in adults with spinal cord injury or multiple sclerosis: a systematic review.
Spinal cord
Spinal Cord
60
10
10.1038/s41393-022-00853-3
eng
2,022
10
null
2,022
9
9
[STUDY DESIGN] Systematic review. [OBJECTIVE] To evaluate the efficacy and safety of mirabegron in patients with neurogenic detrusor overactivity due to SCI or MS. [METHODS] A comprehensive search of the Pubmed, Cochrane, Scopus, and Embase databases was performed. Studies evaluating adult patients with neurogenic detr...
null
0.716
131
Rehabilitation; Medicine; Neurology; Neurology
Medicine; Neuroscience
2,022
36,085,256
Hesitancy for SARS-CoV-2 vaccines and post-vaccination flares in patients with systemic lupus erythematosus.
Vaccine
Vaccine
40
41
10.1016/j.vaccine.2022.08.068
eng
2,022
9
29
2,022
9
6
[OBJECTIVES] To study the rate of SARS-CoV-2 vaccination and post-vaccination disease flares in patients with systemic lupus erythematosus (SLE). [METHODS] Patients who fulfilled ≥ 4 of the ACR criteria for SLE were identified and their SARS-CoV-2 vaccination status was traced. Flares of SLE at 6-week post-vaccination ...
COVID-19; Flares; Hesitancy; Lupus; Vaccination
1.493
222
Immunology and Microbiology; Infectious Diseases; Molecular Medicine; Public Health, Environmental and Occupational Health; Veterinary
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Veterinary
2,022
36,084,758
Selective serotonin reuptake inhibitors and the risk of type 2 diabetes mellitus in youths.
Journal of affective disorders
J Affect Disord
318
null
10.1016/j.jad.2022.08.094
eng
2,022
12
1
2,022
9
6
[BACKGROUND] Selective serotonin reuptake inhibitors (SSRIs) have been associated with type 2 diabetes mellitus (T2DM) in youths, possibly via 5-HT2C, H1 receptors and serotonin transporter (SERT). SSRIs have similar affinity for SERT but variable affinity for 5-HT2C and H1. This study assessed whether SSRIs with stron...
Antidepressants; Children; Diabetes; SSRIs; UK
1.988
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
36,084,419
Smell and Taste Dysfunction in Pediatric Patients With SARS-CoV-2 Infection.
Pediatric neurology
Pediatr Neurol
136
null
10.1016/j.pediatrneurol.2022.07.006
eng
2,022
11
null
2,022
8
1
[INTRODUCTION] Anosmia and hypogeusia are frequent symptoms in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in adults, but their incidence in children is unknown. [OBJECTIVE] Describe the incidence and associated characteristics of olfactory and gustatory dysfunction in children with SARS-CoV-...
Ageusia; Anosmia; Children; Coronavirus; Paucisymptomatic; SARS-CoV-2
0.876
111
Pediatrics, Perinatology and Child Health; Developmental Neuroscience; Neurology; Neurology
Medicine; Neuroscience
2,022
36,084,407
Exploration of factors influencing court outcomes in cases involving minors as victims in Ghana.
Child abuse & neglect
Child Abuse Negl
133
null
10.1016/j.chiabu.2022.105853
eng
2,022
11
null
2,022
9
6
[BACKGROUND] The factors that influence positive court outcomes for cases of child sexual abuse (CSA) have been studied in other contexts but very few such studies exist for Sub-Saharan countries. Knowledge of how such cases fare in these court systems is, however, important for a global assessment of such outcomes. [O...
Case outcome; Child sexual abuse; Complainant characteristics; Conviction; Court; Court process; Ghana; Offender; Victim
null
null
null
null
null
36,084,322
Differential Biopsy Patterns Influence Associations between Multivitamin Use and Prostate Cancer Risk in the Selenium and Vitamin E Cancer Prevention Trial.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Cancer Epidemiol Biomarkers Prev
31
11
10.1158/1055-9965.EPI-22-0453
eng
2,022
11
2
null
null
null
[BACKGROUND] Multivitamin (MVI) use is a common health behavior but there is conflicting evidence from prospective studies about whether this behavior increases or decreases prostate cancer risk. [METHODS] Associations of MVI use and prostate cancer risk were evaluated using data from the Selenium and Vitamin E Cancer ...
null
null
null
null
null
null
36,083,228
Verification of the Mandarin Chinese version of Advance Care Planning Engagement Survey Scale in community-dwelling older people.
International journal of older people nursing
Int J Older People Nurs
18
1
10.1111/opn.12502
eng
2,023
1
null
2,022
9
9
[BACKGROUND] Advance care planning (ACP) has become increasingly critical for older people. The Advance Care Planning Engagement Survey (ACPES) develops targeted interventions for older people by measuring ACP-related behaviours, while previous studies focus only on advance directives. Moreover, while ACPES has English...
advance care planning; older people; reliability; scale; validity
0.765
43
Gerontology
Nursing
2,023
36,082,859
Validation of a Method to Measure the T2 Value from the Color Mapping by Hue Value.
Current medical imaging
Curr Med Imaging
19
8
10.2174/1573405618666220907110157
eng
2,023
null
null
null
null
null
[BACKGROUND] Color mapping using quantitative MRI (Magnetic Resonance Imaging) is now being reported in various medical fields to be useful in showing tissue conditions and morphological perspectives. Specifically, T2 mapping, as one of the color mapping has been used to describe cartilage conditions in orthopedics. Ho...
Blue); Green; HSV (Hue; MRI; RGB (Red; Saturation; T2 mapping; Value); color mapping; medical imaging
0.288
27
Internal Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,023
36,081,709
Initial investigation of predicting hematoma expansion for intracerebral hemorrhage using imaging biomarkers and machine learning.
Proceedings of SPIE--the International Society for Optical Engineering
Proc SPIE Int Soc Opt Eng
12036
null
10.1117/12.2610672
eng
2,022
null
null
2,022
4
4
[PURPOSE] Intracerebral Hemorrhage (ICH) is one of the most devastating types of strokes with mortality and morbidity rates ranging from about 51%-65% one year after diagnosis. Early hematoma expansion (HE) is a known cause of worsening neurological status of ICH patients. The goal of this study was to investigate whet...
Intracerebral hemorrhage; hematoma; keras neural network; machine learning; non-contrast computed tomography; receiver operating characteristic curve
null
null
null
null
null
36,081,675
Staged Head and Neck Reconstruction: Heresy or a Reasoned Approach in a Select Group of Patients?
Craniomaxillofacial trauma reconstruction
Craniomaxillofac Trauma Reconstr
15
3
10.1177/19433875211031361
eng
2,022
9
null
2,021
7
8
[STUDY DESIGN] case series. [OBJECTIVE] The restoration of defects in a single procedure with microvascular free flap reconstruction has become a mainstay of head and neck surgery. Yet in patients with complex defects and pre-existing comorbid medical conditions, a staged-reconstructive approach can enhance the safety ...
head and neck; mandibular reconstruction; microvascular reconstruction; radiation therapy
null
null
null
null
null
36,081,560
Is ICI-based therapy better than chemotherapy for metastatic NSCLC patients who develop EGFR-TKI resistance? A real-world investigation.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.920047
eng
2,022
null
null
2,022
8
23
[PURPOSE] To evaluate the outcomes of immune checkpoint inhibitor (ICI)-based treatments versus classical chemotherapy for metastatic non-small cell lung cancer (NSCLC) patients who develop epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistance and to explore the population that may benefit fr...
EGFR-TKI resistance; EGFR-sensitive mutations; combined therapy; immunotherapy; metastatic NSCLC
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,081,475
Vulnerable populations during COVID-19 response: Health-related quality of life among Chinese population and its influence due to socio-demographic factors and loneliness.
Frontiers in public health
Front Public Health
10
null
10.3389/fpubh.2022.857033
eng
2,022
null
null
2,022
8
15
[BACKGROUND] Infection control policy affected people's wellbeing during the COVID-19 pandemic, especially those vulnerable populations. This study aimed to compare the health-related quality of life (HRQoL) of the Hong Kong (HK) Chinese population under the pandemic with the normative profiles and explore its influenc...
COVID-19 pandemic; EQ-5D-5L; health-related quality of life; loneliness; vulnerable populations
1.125
119
Public Health, Environmental and Occupational Health
Medicine
2,022
36,081,468
Development of a culturally adaptable internet-based cognitive behavioral therapy for Japanese women with bulimia nervosa.
Frontiers in psychiatry
Front Psychiatry
13
null
10.3389/fpsyt.2022.942936
eng
2,022
null
null
2,022
8
23
[BACKGROUND] The process of cultural adaptation of internet-based cognitive behavioral therapy (ICBT) programs for bulimia nervosa (BN) have rarely been reported despite the potential influence of cultural adaptation of psychosocial interventions on therapeutic response. [AIM] This study aimed to illustrate development...
bulimia nervosa (BN); cultural adaptation; cultural sensitivity; ecological validity; internet-based cognitive behavioral therapy (ICBT)
1.222
134
Psychiatry and Mental Health
Medicine
2,022
36,081,449
Association Between Obstetric History and Urinary Incontinence in a Cohort of Resistance-Trained Women.
International journal of women's health
Int J Womens Health
14
null
10.2147/IJWH.S367110
eng
2,022
null
null
2,022
9
2
[PURPOSE] Urinary incontinence has the potential to reduce participation in sport and exercise and diminish athletic performance. The purpose of this study was to explore the association between obstetric history and urinary incontinence in a cohort of resistance-trained women. [PATIENTS AND METHODS] This international...
pelvic floor; pregnancy; resistance training; strength training
0.687
71
Maternity and Midwifery; Obstetrics and Gynecology; Oncology
Medicine; Nursing
2,022
36,081,298
Effect of the food processing degree on cardiometabolic health outcomes: A prospective approach in childhood.
Clinical nutrition (Edinburgh, Scotland)
Clin Nutr
41
10
10.1016/j.clnu.2022.07.034
eng
2,022
10
null
2,022
8
8
[BACKGROUND AND AIMS] Ultra-processed foods (UPF) consumption has increased greatly over the last decades but its impact on health remains unclear. This study aimed to evaluate the prospective effect of different degrees of food processing on children's cardiometabolic profile. [METHODS] Children from the Portuguese po...
Cardiometabolic health; Children; Cohort studies; Obesity; Ultra-processed foods
1.658
183
Critical Care and Intensive Care Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
36,081,294
Computer customization errors compromised the optimization of trace element repletion dose after major burns.
Clinical nutrition (Edinburgh, Scotland)
Clin Nutr
41
10
10.1016/j.clnu.2022.08.009
eng
2,022
10
null
2,022
8
19
[BACKGROUND AND AIMS] Major burns develop acute trace element (TE) deficiencies due to exudative losses of copper, selenium, and zinc from the wounds. A repletion strategy has been shown to decrease infectious and surgical complications. The TE doses have been adapted over time and the last adaptation, was not followed...
Copper; Micronutrient; Monitoring; Nutrition therapy; Prescription; Selenium
1.658
183
Critical Care and Intensive Care Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
36,076,665
Evaluation of Progesterone Receptor Antagonist and Maxi-K Channel Agonist as Neuroprotective in Feeney's Weight Drop Model of TBI.
Neurology India
Neurol India
70
4
10.4103/0028-3886.355164
eng
2,022
null
null
null
null
null
[BACKGROUND] Neuroprotection in traumatic brain injury (TBI) is an unmet medical need. [OBJECTIVE] We evaluated two agents, aglepristone (progesterone receptor antagonist) and N-salicyloyltryptamine (STP) (activator of Maxi-K channel in GH3 cells), for neuroprotection in Feeney's weight drop model of TBI. [MATERIAL AND...
Anti-progesterone; Maxi-K channel; craniotomy; neuroprotective; progesterone; traumatic brain injury; weight drop apparatus
0.448
59
Neurology; Neurology
Medicine; Neuroscience
2,022
36,076,219
Does financial literacy influence preventive health check-up behavior in Japan? a cross-sectional study.
BMC public health
BMC Public Health
22
1
10.1186/s12889-022-14079-8
eng
2,022
9
8
2,022
9
8
[BACKGROUND] General health check-ups are an important element of healthcare, as they are designed to detect diseases, thereby reducing morbidity and mortality. Recent studies have found that financial literacy promotes preventive healthcare usage and reduces risky health behaviors such as smoking, lack of exercise, an...
Financial education; Financial literacy; Health behavior; Health investment; Japan; Preventive health check-up; Rationality explanation
1.307
211
Public Health, Environmental and Occupational Health
Medicine
2,022
36,075,763
Barriers to Coronavirus Disease 19 vaccination in patients with obesity.
American journal of surgery
Am J Surg
225
2
10.1016/j.amjsurg.2022.08.021
eng
2,023
2
null
2,022
9
1
[BACKGROUND] Patients with obesity are at a high risk of severe disease and death from Coronavirus Disease 2019 (COVID-19). Vaccination offers a safe and effective means of reducing this risk. The rate of COVID-19 vaccine refusal in patients with obesity is unknown. [METHODS] Patients with obesity were administered val...
COVID-19; Obesity; Vaccination; Vaccine hesitancy
0.897
173
Medicine; Surgery
Medicine
2,023
36,075,623
Incidence and Predictors of Atrial Fibrillation in Cardiac Sarcoidosis: A Multimodality Imaging Study.
JACC. Cardiovascular imaging
JACC Cardiovasc Imaging
15
9
10.1016/j.jcmg.2022.02.025
eng
2,022
9
null
2,022
5
11
[BACKGROUND] In cardiac sarcoidosis (CS), the risk and predictors of new-onset atrial fibrillation (AF) are poorly known. [OBJECTIVES] The authors evaluated the incidence and characteristics of AF in newly diagnosed CS. [METHODS] The authors studied 118 patients (78 women, mean age 50 years) with AF-naive CS having und...
atrial fibrillation; cardiac magnetic resonance; cardiac sarcoidosis; positron emission tomography
null
null
null
null
null
36,075,579
Preoperative CA125 as a risk factor for symptom recurrence of adenomyosis after ultrasound-guided high-intensity focused ultrasound ablation surgery.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
Int J Hyperthermia
39
1
10.1080/02656736.2022.2107716
eng
2,022
null
null
null
null
null
[OBJECTIVES] To investigate the relationship between preoperative CA125 and symptom recurrence in adenomyosis after ultrasound-guided high-intensity focused ultrasound ablation surgery (FUAS). [METHODS] A total of 502 adenomyosis patients after FUAS in Affiliated Nanchong Central Hospital of North Sichuan Medical Colle...
CA125; adenomyosis; focused ultrasound ablation surgery; symptom recurrence
0.762
103
Medicine; Physiology; Physiology; Radiological and Ultrasound Technology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine
2,022
36,075,273
Artemisia argyi extract induces apoptosis in human gemcitabine-resistant lung cancer cells via the PI3K/MAPK signaling pathway.
Journal of ethnopharmacology
J Ethnopharmacol
299
null
10.1016/j.jep.2022.115658
eng
2,022
12
5
2,022
9
6
[ETHNOPHARMACOLOGICAL RELEVANCE] Artemisia argyi H. Lév. Vaniot (Asteraceae), also called "Chinese mugwort", is frequently used as a herbal medicine in China, Japan, Korea, and eastern parts of Russia. It is known as "ai ye" in China and "Gaiyou" in Japan. In ancient China, the buds and leaves of A. argyi were commonl...
Adjuvant chemotherapy; Artemisia argyi; Gemcitabine resistance; Lung cancer; Traditional Chinese medicine
0.833
243
Drug Discovery; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,022
36,074,475
Association of rs2072446 in the NGFR gene with the risk of Alzheimer's disease and amyloid-β deposition in the brain.
CNS neuroscience therapeutics
CNS Neurosci Ther
28
12
10.1111/cns.13965
eng
2,022
12
null
2,022
9
8
[INTRODUCTION AND AIMS] Alzheimer's disease (AD) is the most common form of dementia with a complex genetic background. The cause of sporadic AD (sAD) remains largely unknown. Increasing evidence shows that genetic variations play a crucial role in sAD. P75 neurotrophin receptor (p75NTR, encoded by NGFR) plays a critic...
ADNI; Alzheimer's disease; p75NTR; polymorphism
null
null
null
null
null
36,074,415
Assessing Prognostic Value of Quantitative Neck Dissection Quality Measures in Patients With Clinically Node-Negative Oral Cavity Squamous Cell Carcinoma.
JAMA otolaryngology-- head neck surgery
JAMA Otolaryngol Head Neck Surg
148
10
10.1001/jamaoto.2022.2312
eng
2,022
10
1
null
null
null
[IMPORTANCE] In clinically localized (T1-2) oral cavity squamous cell carcinoma (OCSCC), regional lymph node metastasis is associated with a poor prognosis. Given the high propensity of subclinical nodal disease in these patients, upfront elective neck dissections (END) for patients with clinically node-negative diseas...
null
null
null
null
null
null
36,074,035
What Types of Burden Experienced by Family Caregivers of Dementia Patients Are Related to Their Life Satisfaction?
The journals of gerontology. Series A, Biological sciences and medical sciences
J Gerontol A Biol Sci Med Sci
78
6
10.1093/gerona/glac183
eng
2,023
6
1
null
null
null
[BACKGROUND] As the burdens related to dementia caregiving are vast, this study aimed to examine the relationship between life satisfaction and different types of burden reported by family caregivers of patients with dementia. [METHODS] Data from the 2019 Korea Community Health Survey were used. The association between...
Caregivers; Caregiving burden; Dementia; Life satisfaction
1.285
230
Geriatrics and Gerontology; Aging
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,073,992
Can Technology Assistance be Cost Effective in TKA? A Simulation-Based Analysis of a Risk-prioritized, Practice-specific Framework.
Clinical orthopaedics and related research
Clin Orthop Relat Res
481
1
10.1097/CORR.0000000000002375
eng
2,023
1
1
2,022
9
8
[BACKGROUND] Robotic, navigated, and patient-specific instrumentation (PSI) TKA procedures have been introduced to improve component placement precision and improve implant survivorship and other clinical outcomes. However, the best available evidence has shown that these technologies are ineffective in reducing revisi...
null
1.387
244
Medicine; Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,023
36,073,322
Efficacy and toxicity of hydrogen peroxide producing electrochemical bandages in a porcine explant biofilm model.
Journal of applied microbiology
J Appl Microbiol
133
6
10.1111/jam.15812
eng
2,022
12
null
2,022
9
22
[AIMS] Effects of H2 O2 producing electrochemical-bandages (e-bandages) on methicillin-resistant Staphylococcus aureus colonization and biofilm removal were assessed using a porcine explant biofilm model. Transport of H2 O2 produced from the e-bandage into explant tissue and associated potential toxicity were evaluated...
Staphylococcus aureus; biofilm; electroceutical; electrochemical bandage; hydrogen peroxide; porcine explant
0.774
195
Applied Microbiology and Biotechnology; Biotechnology; Medicine
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,022
36,073,024
Does promoting plant-based products in Veganuary lead to increased sales, and a reduction in meat sales? A natural experiment in a supermarket setting.
Public health nutrition
Public Health Nutr
25
11
10.1017/S1368980022001914
eng
2,022
11
null
2,022
9
8
[OBJECTIVE] To explore changes in plant-based and meat product sales during and after implementation of a multi-component in-store intervention implemented by a major UK food retailer. Secondary objectives included exploring differences by store format and area affluence. [DESIGN] The intervention increased the visibil...
Behaviour change; Food retail; Impact evaluation; Intervention; Meat reduction; Sustainable diets; Veganuary
0.874
173
Medicine; Nutrition and Dietetics; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,022
36,072,232
Ovarian cancer in Lebanese women: a 12-year comparative epidemiological study and trend analysis.
Ecancermedicalscience
Ecancermedicalscience
16
null
10.3332/ecancer.2022.1409
eng
2,022
null
null
2,022
6
13
[PURPOSE] Over the last decade, Lebanon has experienced an increase in the rate of cancer patients. The aim of this study is to investigate the incidence rates of ovarian cancer in Lebanese women over a period of 12 years and to compare them to other countries. [METHODS] Data were collected from the Lebanese National C...
Lebanon; epidemiology; gynaecology; oncology; ovarian cancer
0.665
51
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,072,066
The Findings of Pulmonary Nocardiosis on Chest High Resolution Computed Tomography: Single centre experience and review of literature.
Sultan Qaboos University medical journal
Sultan Qaboos Univ Med J
22
3
10.18295/squmj.9.2021.131
eng
2,022
8
null
2,022
8
25
[OBJECTIVES] Pulmonary nocardiosis is a rare opportunistic infection that is often encountered in immunocompromised patients, in particular those with the HIV infection and in solid organ transplant recipients. As the number of immunocompromised patients increase, the number of patients with pulmonary nocardiosis is al...
Computed Tomography; Oman; Pulmonary Nocardiosis
0.291
38
Medicine
Medicine
2,022
36,071,513
Escalation of care in children at high risk of clinical deterioration in a tertiary care children's hospital using the Bedside Pediatric Early Warning System.
BMC pediatrics
BMC Pediatr
22
1
10.1186/s12887-022-03555-0
eng
2,022
9
7
2,022
9
7
[BACKGROUND] Escalation and de-escalation are a routine part of high-quality care that should be matched with clinical needs. The aim of this study was to describe escalation of care in relation to the occurrence and timing of Pediatric Intensive Care Unit (PICU) admission in a cohort of pediatric inpatients with acute...
BedsidePEWS; Escalation of care; Intensive care; PEWS; Pediatric; Track and trigger tool; Urgent admission
0.742
106
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,071,505
Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation.
Alzheimer's research therapy
Alzheimers Res Ther
14
1
10.1186/s13195-022-01071-y
eng
2,022
9
7
2,022
9
7
[BACKGROUND] Measurements of the amyloid-β (Aβ) 42/40 ratio in blood plasma may support the early diagnosis of Alzheimer's disease and aid in the selection of suitable participants in clinical trials. Here, we compared the diagnostic performance of fully automated prototype plasma Aβ42/40 assays with and without pre-an...
Biomarker assay; Immunoprecipitation; Pre-analytical sample workup
null
null
null
null
null
36,071,483
Clinical management and acute exacerbations in patients with idiopathic pulmonary fibrosis in Spain: results from the OASIS study.
Respiratory research
Respir Res
23
1
10.1186/s12931-022-02154-y
eng
2,022
9
7
2,022
9
7
[BACKGROUND] Idiopathic pulmonary fibrosis (IPF) is a progressive disease associated with decline in lung function and poor prognosis entailing significant impairment in quality of life and high socioeconomic burden. The aim of this study was to characterize clinical management and resources utilization of patients wit...
Clinical management; Early treatment; IPF acute exacerbations; IPF management; IPF progression; Idiopathic pulmonary fibrosis (IPF)
1.753
134
Pulmonary and Respiratory Medicine
Medicine
2,022
36,071,443
Availability of services for the diagnosis and treatment of infertility in The Gambia`s public and private health facilities: a cross-sectional survey.
BMC health services research
BMC Health Serv Res
22
1
10.1186/s12913-022-08514-0
eng
2,022
9
7
2,022
9
7
[BACKGROUND] Infertility is a long-standing reproductive health issue, which affects both men and women worldwide and it is especially problematic in the Global South. In sub-Saharan Africa, understanding the current availability of diagnostic and treatment services for infertility is important because this could guide...
ART; Fertility care; Infertility services; Private care; Sub-Saharan Africa; The Gambia
0.964
157
Health Policy
Medicine
2,022
36,071,240
Improvement of Nasal Dorsal Onlay Graft Appearance after Augmentation Rhinoplasty with Costal Cartilage for Thin-Skinned Patients.
Aesthetic plastic surgery
Aesthetic Plast Surg
47
1
10.1007/s00266-022-03082-4
eng
2,023
2
null
2,022
9
7
[BACKGROUND] The camouflage of the nasal dorsum is very important for thin-skinned patients. In this study, the authors presented an improved method for these patients and evaluated the safety and efficacy of this method in augmentation rhinoplasty. [METHODS] Fifty-two thin-skinned nose Chinese patients, ranging in age...
Rhinoplasty; Rhinoplasty outcomes evaluation; Thin nasal skin
0.909
85
Surgery
Medicine
2,023
36,071,104
Costs associated with acute kidney injury in critically Ill neonates with patent Ductus arteriosus: pediatric health information system (PHIS) analysis.
Journal of perinatology : official journal of the California Perinatal Association
J Perinatol
42
12
10.1038/s41372-022-01499-y
eng
2,022
12
null
2,022
9
7
[OBJECTIVE] Compare costs of hospitalization between critically-ill neonates with patent ductus arteriosus (PDA) who did and did not develop acute kidney injury (AKI). [STUDY DESIGN] Using the Children's Hospital Association's Pediatric Health Information System (PHIS) database, we ascertained the marginal estimated to...
null
0.98
119
Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine
2,022
36,070,861
Continuous Thermoregulatory Responses to a Mass-Participation 89-km Ultramarathon Road Race.
International journal of sports physiology and performance
Int J Sports Physiol Perform
17
11
10.1123/ijspp.2022-0043
eng
2,022
11
1
2,022
9
7
[PURPOSE] To continuously measure body core temperature (Tc) throughout a mass-participation ultramarathon in subelite recreational runners to quantify Tc magnitude and the influence of aerobic fitness and body fat. [METHODS] Twenty-three participants (19 men and 4 women; age 45 [9] y; body mass 72.0 [9.3] kg; body fat...
aerobic fitness; body fat; core temperature; dehydration; hyperthermia
1.333
102
Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,022
36,070,781
Estimation of Mycophenolic Acid Exposure in Chinese Renal Transplant Patients by a Joint Deep Learning Model.
Therapeutic drug monitoring
Ther Drug Monit
44
6
10.1097/FTD.0000000000001020
eng
2,022
12
1
null
null
null
[BACKGROUND] To predict mycophenolic acid (MPA) exposure in renal transplant recipients using a deep learning model based on a convolutional neural network with bilateral long short-term memory and attention methods. [METHODS] A total of 172 Chinese renal transplant patients were enrolled in this study. The patients we...
null
0.466
105
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,070,704
Association between Gut Microbiota with Mild Cognitive Impairment and Alzheimer's Disease in a Thai Population.
Neuro-degenerative diseases
Neurodegener Dis
22
2
10.1159/000526947
eng
2,022
null
null
2,022
9
7
[BACKGROUND] Mild cognitive impairment (MCI) and Alzheimer's disease (AD) are common in older adults. Much recent work has implicated the connection between the gut and the brain via bidirectional communication of the gastrointestinal tract and the central nervous system through biochemical signaling. Altered gut micro...
Amyloid; Microbiome; Mild cognitive impairment; Positron emission tomography
null
null
null
null
null
36,070,629
Validity of at-home rapid antigen lateral flow assay and artificial intelligence read to detect SARS-CoV-2.
Diagnostic microbiology and infectious disease
Diagn Microbiol Infect Dis
104
3
10.1016/j.diagmicrobio.2022.115763
eng
2,022
11
null
2,022
7
7
[BACKGROUND] The gold standard for COVID-19 diagnosis-reverse-transcriptase polymerase chain reaction (RT-PCR)- is expensive and often slow to yield results whereas lateral flow tests can lack sensitivity. [METHODS] We tested a rapid, lateral flow antigen (LFA) assay with artificial intelligence read (LFAIR) in subject...
Artificial intelligence; COVID-19; Diagnostic accuracy; Rapid antigen test; SARS-CoV-2; Validity
null
null
null
null
null
36,069,161
Clinical outcomes and predictors of technical failure of endoscopic transpapillary gallbladder drainage in acute cholecystitis.
Scandinavian journal of gastroenterology
Scand J Gastroenterol
58
3
10.1080/00365521.2022.2118554
eng
2,023
3
null
2,022
9
7
[BACKGROUND AND AIMS] Endoscopic transpapillary gallbladder drainage (ETGBD) has been performed as an alternative therapy against cholecystectomy in patients with acute cholecystitis. To date, few studies have reported the safety, efficacy, and factors affecting ETGBD. We evaluated the clinical outcomes and predictors ...
Acute cholecystitis; cystic duct injury; endoscopic retrograde cholangiopancreatography; endoscopic transpapillary gallbladder drainage; stones
0.669
133
Gastroenterology
Medicine
2,023
36,068,638
Prognostic factors for the development of systemic lupus erythematosus in patients with immune thrombocytopenia.
Arthritis research therapy
Arthritis Res Ther
24
1
10.1186/s13075-022-02901-y
eng
2,022
9
6
2,022
9
6
[BACKGROUND] Patients with immune thrombocytopenia (ITP) have a risk of developing systemic lupus erythematosus (SLE). We sought to examine the clinical characteristics of patients with primary ITP who later developed SLE and identified the risk factors for the development of SLE. [METHODS] We retrospectively examined ...
Antinuclear antibody; Immune thrombocytopenia; Organ bleeding; Systemic lupus erythematosus; Thrombocytopenia
null
null
null
null
null
36,068,627
Trends and correlates of intimate partner violence (IPV) victimization in Rwanda: results from the 2015 and 2020 Rwanda Demographic Health Survey (RDHS 2015 and 2020).
BMC women's health
BMC Womens Health
22
1
10.1186/s12905-022-01951-3
eng
2,022
9
6
2,022
9
6
[BACKGROUND] Intimate partner violence (IPV) is reported to be a public health issue given its magnitude and long-lasting consequences. Men are generally thought to be perpetrators of IPV, but they can also be victims. In Rwanda, the experience of men as victims has not yet been described and characterized. The aim of ...
DHS; Intimate partner violence; Rwanda; Violence victimization
0.775
73
Medicine; Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,022
36,068,582
Pulmonary function and chest computed tomography abnormalities 6-12 months after recovery from COVID-19: a systematic review and meta-analysis.
Respiratory research
Respir Res
23
1
10.1186/s12931-022-02163-x
eng
2,022
9
6
2,022
9
6
[BACKGROUND] Some coronavirus disease 2019 (COVID-19) survivors experience prolonged and varying symptoms, a condition termed post-acute COVID-19 syndrome (PACS). However, the prevalence of chronic pulmonary sequelae of PACS during long-term follow-up remains unclear. Several studies have examined this issue and report...
COVID-19; Complications; Computed tomography; Meta-analysis; Respiratory Function Tests
1.753
134
Pulmonary and Respiratory Medicine
Medicine
2,022
36,068,570
Competing at the Cybathlon championship for people with disabilities: long-term motor imagery brain-computer interface training of a cybathlete who has tetraplegia.
Journal of neuroengineering and rehabilitation
J Neuroeng Rehabil
19
1
10.1186/s12984-022-01073-9
eng
2,022
9
6
2,022
9
6
[BACKGROUND] The brain-computer interface (BCI) race at the Cybathlon championship, for people with disabilities, challenges teams (BCI researchers, developers and pilots with spinal cord injury) to control an avatar on a virtual racetrack without movement. Here we describe the training regime and results of the Ulster...
Competition; Electroencephalography (EEG); Long-term training; Motor imagery; Neurofeedback; Neurogaming; Tetraplegia
1.134
129
Health Informatics; Rehabilitation
Medicine
2,022
36,068,491
Radiation-response in primary fibroblasts of long-term survivors of childhood cancer with and without second primary neoplasms: the KiKme study.
Molecular medicine (Cambridge, Mass.)
Mol Med
28
1
10.1186/s10020-022-00520-6
eng
2,022
9
6
2,022
9
6
[BACKGROUND] The etiology and most risk factors for a sporadic first primary neoplasm in childhood or subsequent second primary neoplasms are still unknown. One established causal factor for therapy-associated second primary neoplasms is the exposure to ionizing radiation during radiation therapy as a mainstay of cance...
Differential gene expression; High dose; Low dose; NGS; Pathway analysis; RNA-Seq; Radiation experiment; Radiation response
1.245
136
Genetics; Genetics; Molecular Medicine; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,067,939
Gender disparities in shoulder and elbow publications.
Journal of shoulder and elbow surgery
J Shoulder Elbow Surg
31
12
10.1016/j.jse.2022.07.018
eng
2,022
12
null
2,022
9
5
[HYPOTHESIS/BACKGROUND] Female representation in orthopedics, and specifically shoulder and elbow surgery, lags behind other surgical subspecialities. There has been a growing interest in recent years to better characterize, and address, gender disparities in the field. The purpose of this investigation was to characte...
Shoulder; authorship; elbow; gender; publication
1.666
178
Medicine; Orthopedics and Sports Medicine; Sports Science; Surgery
Health Professions; Medicine
2,022
36,067,799
Iron Salts, High Levels of Hemoglobin and Ferritin in Pregnancy, and Development of Gestational Diabetes: A Systematic Review.
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia
Rev Bras Ginecol Obstet
44
11
10.1055/s-0042-1755460
eng
2,022
11
null
2,022
9
6
[OBJECTIVE] The aim of this study was to systematically review literature on the use of iron supplements (not including iron derived from diet), increased levels of hemoglobin and/or ferritin, and the risk of developing gestational diabetes mellitus (GDM). [DATA SOURCE] The following databases were searched, from the s...
null
0.295
32
Obstetrics and Gynecology
Medicine
2,022
36,067,447
End-of-Life Health Resource Utilization for Limited English-Proficient Patients With Advanced Non-Small-Cell Lung Cancer.
JCO oncology practice
JCO Oncol Pract
18
10
10.1200/OP.22.00110
eng
2,022
10
null
2,022
9
6
[PURPOSE] Limited English-proficient (LEP) patients with non-small-cell lung cancer (NSCLC) may receive less palliative care services and more likely to receive aggressive end-of-life (EoL) care. Goals of this retrospective cohort study are to compare access to community palliative home care (CPHC), do not resuscitate ...
null
1.349
85
Health Policy; Oncology; Oncology
Medicine; Nursing
2,022
36,067,374
Gleason Grade 1 Prostate Cancer Volume at Biopsy Is Associated With Upgrading but Not Adverse Pathology or Recurrence After Radical Prostatectomy: Results From a Large Institutional Cohort.
The Journal of urology
J Urol
209
1
10.1097/JU.0000000000002956
eng
2,023
1
null
2,022
9
6
[PURPOSE] Clinical guidelines suggest that for low-grade, clinically localized prostate cancer, patients with higher volume of disease at diagnosis may benefit from definitive therapy, although the data remain unclear. Our objective was to determine associations between low-grade prostate cancer volume and outcomes in ...
prostatectomy; prostatic neoplasms; watchful waiting
1.938
291
Urology
Medicine
2,023
36,067,353
Kinetic parameters related to nitrogen uptake in 'Okinawa' peach rootstocks are altered by 'Chimarrita' scion Nitrogen uptake in 'Okinawa' peach rootstock.
Journal of the science of food and agriculture
J Sci Food Agric
103
2
10.1002/jsfa.12203
eng
2,023
1
30
2,022
10
28
[BACKGROUND] The kinetic parameters of peach rootstock are a major factor contributing to its nitrogen (N) uptake efficiency, which directly affects the yield and quality parameters. However, the impact of grafting on N kinetic parameters is not sufficiently known as rootstocks are grafted with other scion cultivars be...
Michaelis-Menten constant; Prunus persica L; maximum uptake rate; minimal concentration; nutrient influx
null
null
null
null
null
36,067,143
A single-centre study on predictors and determinants of pubertal delay and growth impairment in Epidermolysis Bullosa.
PloS one
PLoS One
17
9
10.1371/journal.pone.0274072
eng
2,022
null
null
2,022
9
6
[BACKGROUND] Delayed puberty is a possible complication of Epidermolysis Bullosa (EB), though the actual incidence is still unknown. In chronic illnesses delayed puberty should be correctly managed since, if untreated, can have detrimental effects on adult height attainment, peak bone mass achievement and psychological...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,067,113
Surface-Acoustic-Wave (SAW)-Driven Device for Three-Dimensional Cell Manipulation.
IEEE transactions on bio-medical engineering
IEEE Trans Biomed Eng
70
3
10.1109/TBME.2022.3201990
eng
2,023
3
null
2,023
2
17
[UNLABELLED] Cell orientation is a necessary step in micromanipulation, which significantly affects the outcomes of cell manipulation. Existing cell orientation techniques include the trial-and-error manual approach that suffers from low efficiency, the mechanical contact approaches that have problems of being invasive...
null
null
null
null
null
null
36,066,786
Meningioma in patients exposed to progestin drugs: results from a real-life screening program.
Journal of neuro-oncology
J Neurooncol
160
1
10.1007/s11060-022-04124-2
eng
2,022
10
null
2,022
9
6
[PURPOSE] To report the results of systematic meningioma screening program implemented by French authorities in patients exposed to progestin therapies (cyproterone (CPA), nomegestrol (NA), and chlormadinone (CMA) acetate). [METHODS] We conducted a prospective monocentric study on patients who, between September 2018 a...
Chlormadinone acetate; Cyproterone acetate; Mass screening; Meningioma; Nomegestrol acetate
1.178
141
Neurology; Neurology; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,022
36,066,660
Shorter versus longer duration of Amoxicillin-based treatment for pediatric patients with community-acquired pneumonia: a systematic review and meta-analysis.
European journal of pediatrics
Eur J Pediatr
181
11
10.1007/s00431-022-04603-8
eng
2,022
11
null
2,022
9
6
[UNLABELLED] Streptococcus pneumoniae is the most common typical bacterial cause of pneumonia among children. The World Health Organization (WHO) recommends a 5-day Amoxicillin-based empiric treatment. However, longer treatments are frequently used. This study aimed to compare shorter and longer Amoxicillin regimens fo...
Antibiotics; Children; Community-acquired pneumonia; Duration of therapy; Short-course treatment
1.036
115
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,066,514
Diagnosis and Treatment of Myelodysplastic Syndromes: A Review.
JAMA
JAMA
328
9
10.1001/jama.2022.14578
eng
2,022
9
6
null
null
null
[IMPORTANCE] Myelodysplastic neoplasms (MDS), formerly known as myelodysplastic syndromes, are clonal hematopoietic malignancies that cause morphologic bone marrow dysplasia along with anemia, neutropenia, or thrombocytopenia. MDS are associated with an increased risk of acute myeloid leukemia (AML). The yearly inciden...
null
null
null
null
null
null
36,066,345
How Does Health-Related Quality of Life Change Over Time in Cancer Survivors Following an Admission to the Intensive Care Unit?: An Integrative Review.
Cancer nursing
Cancer Nurs
47
2
10.1097/NCC.0000000000001157
eng
null
null
null
2,022
12
11
[BACKGROUND] Cancer survivors account for 15% to 20% of all intensive care unit (ICU) admissions. In general ICU populations, patients are known to experience reduced health-related quality of life (HRQoL). However, little is known about HRQoL impacts among cancer survivors following a critical illness in ICU. [OBJECTI...
null
null
null
null
null
null
36,066,318
Glomerular macrophage index (GMI) in kidney transplant biopsies is associated with graft outcome.
Clinical transplantation
Clin Transplant
36
12
10.1111/ctr.14816
eng
2,022
12
null
2,022
9
22
[BACKGROUND] Macrophages in renal transplants have been shown to participate in antibody-mediated rejection and are associated with impaired renal function. We calculated the glomerular macrophage index (GMI) in a large transplant biopsy cohort, studied its quantity in different diagnostic groups, to clarify its possib...
glomerular macrophage index; graft outcome; macrophage; rejection; renal transplant biopsies
0.842
90
Transplantation
Medicine
2,022
36,065,982
Transcriptome analysis of the response to thyroid hormone in Xenopus neural stem and progenitor cells.
Developmental dynamics : an official publication of the American Association of Anatomists
Dev Dyn
252
2
10.1002/dvdy.535
eng
2,023
2
null
2,022
9
19
[BACKGROUND] The thyroid hormones-thyroxine (T4) and 3,5,3'triiodothyronine (T3)-regulate the development of the central nervous system (CNS) in vertebrates by acting in different cell types. Although several T3 target genes have been identified in the brain, the changes in the transcriptome in response to T3 specifica...
mitochondria; neural stem and progenitor cells; proteasome; ribosome biogenesis; thyroid hormone
null
null
null
null
null
36,065,739
Examining the concordance of retinal ganglion cell counts generated using measures of structure and function.
Ophthalmic physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
Ophthalmic Physiol Opt
42
6
10.1111/opo.13041
eng
2,022
11
null
2,022
9
6
[PURPOSE] There are several indirect methods used to estimate retinal ganglion cell (RGC) count in an individual eye, but there is limited information as to the agreement between these methods. In this work, RGC receptive field (RGC-RF) count underlying a spot stimulus (0.43°, Goldmann III) was calculated and compared ...
peripheral grating resolution acuity; retinal ganglion cell count; structure-function relationship
null
null
null
null
null
36,065,722
Altered biventricular function in neonatal hypoxic-ischaemic encephalopathy: a case-control echocardiographic study.
Cardiology in the young
Cardiol Young
33
9
10.1017/S1047951122002839
eng
2,023
9
null
2,022
9
6
[BACKGROUND] In newborns with hypoxic-ischaemic encephalopathy, more profound altered right and left ventricular function has been associated with mortality or brain injury. Mechanisms underlying cardiac dysfunction in this population are thought to be related to the persistence of increased pulmonary vascular resistan...
Brain injury; cardiac dysfunction; hypoxic-ischaemic encephalopathy; speckle-tracking echocardiography; therapeutic hypothermia
0.379
68
Cardiology and Cardiovascular Medicine; Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,023
36,065,360
The efficacy profiles of concurrent chemoradiotherapy with intensity-modulated radiotherapy followed by durvalumab in patients with unresectable stage III non-small cell lung cancer: A multicenter retrospective cohort study.
Clinical and translational radiation oncology
Clin Transl Radiat Oncol
37
null
10.1016/j.ctro.2022.08.010
eng
2,022
11
null
2,022
8
23
[PURPOSE] Intensity-modulated radiotherapy (IMRT) is currently used more commonly than 3-dimensional conformal radiation for definitive thoracic radiation. We examined the efficacy profiles of concurrent chemoradiotherapy (CCRT) with IMRT after durvalumab became clinically available. [METHODS] We reviewed the clinical ...
3D-CRT, 3-dimensional conformal radiation therapy; 95% CI, 95% confidence interval; AE, adverse event; CCRT, concurrent chemoradiotherapy; Concurrent chemoradiotherapy; Durvalumab consolidation; FEV1, forced expiratory volume in 1 second; HR, hazard ratio; IMRT, intensity-modulated radiotherapy; IO, immune-oncology; In...
1.104
37
Radiology, Nuclear Medicine and Imaging; Oncology
Medicine
2,022
36,065,278
Perception Towards COVID-19 Related Symptoms and Traditional Medicine Used for Their Management Among Patients and Their Attendants in Ethiopian Comprehensive Specialized Hospitals: A Cross-Sectional Study.
Infection and drug resistance
Infect Drug Resist
15
null
10.2147/IDR.S380211
eng
2,022
null
null
2,022
8
30
[BACKGROUND] Since the beginning of the pandemic, scientists and researchers are highly engaged in the discovery and production of vaccines and specific treatments for COVID-19. In China, the National Health Commission has declared the use of herbal medicine combined with Western medicine as a treatment for COVID-19 an...
COVID-19; Ethiopia; complementary and alternative medicine
0.84
74
Infectious Diseases; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,065,156
Multimodal Magnetic Resonance Imaging Depicts Widespread and Subregion Specific Anomalies in the Thalamus of Early-Psychosis and Chronic Schizophrenia Patients.
Schizophrenia bulletin
Schizophr Bull
49
1
10.1093/schbul/sbac113
eng
2,023
1
3
null
null
null
[BACKGROUND AND HYPOTHESIS] Although the thalamus has a central role in schizophrenia pathophysiology, contributing to sensory, cognitive, and sleep alterations, the nature and dynamics of the alterations occurring within this structure remain largely elusive. Using a multimodal magnetic resonance imaging (MRI) approac...
MRI; early-psychosis; microstructure; nuclei; schizophrenia; thalamus
2.249
228
Psychiatry and Mental Health
Medicine
2,023
36,064,726
Analytical performance of a canine ELISA monocyte chemoattractant protein-1 assay for use in cats and evaluation of circulating levels in normal weight and obese cats.
Acta veterinaria Scandinavica
Acta Vet Scand
64
1
10.1186/s13028-022-00640-3
eng
2,022
9
5
2,022
9
5
[BACKGROUND] In human and murine obesity, adipose tissue dwelling macrophages and adipocytes produce monocyte chemoattractant protein-1 (MCP-1) leading to systemic low-grade inflammation. The aim of the study was to validate a canine MCP-1 ELISA assay for use in cats and to investigate whether a difference in MCP-1 con...
Feline; Inflammation; MCP-1; Obesity; Sensitivity; Specificity; Validation
0.555
68
Veterinary; Medicine
Medicine; Veterinary
2,022
36,064,618
Potential benefits of a virtual, home-based combined exercise and mindfulness training program for HSC transplant survivors: a single-arm pilot study.
BMC sports science, medicine rehabilitation
BMC Sports Sci Med Rehabil
14
1
10.1186/s13102-022-00554-7
eng
2,022
9
5
2,022
9
5
[PURPOSE] Impaired quality of life (QOL) including reduced physical fitness is a recognized late effect of hemopoietic cell transplantation (HCT). Guided exercise and mindfulness-based stress management (MBSM) programs have shown promise, mainly in the inpatient setting. We aimed to examine the feasibility of a virtual...
Allogeneic HCT; Mindfulness; Physical exercise; QOL; Telehealth
null
null
null
null
null
36,064,550
MICAL2 contributes to gastric cancer cell migration via Cdc42-dependent activation of E-cadherin/β-catenin signaling pathway.
Cell communication and signaling : CCS
Cell Commun Signal
20
1
10.1186/s12964-022-00952-x
eng
2,022
9
5
2,022
9
5
[BACKGROUND] Gastric cancer is a common and lethal human malignancy worldwide and cancer cell metastasis is the leading cause of cancer-related mortality. MICAL2, a flavoprotein monooxygenase, is an important regulator of epithelial-to-mesenchymal transition. The aim of this study was to explore the effects of MICAL2 o...
Gastric cancer; MICAL2; Migration
1.868
98
Biochemistry; Cell Biology; Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,022
36,064,517
Exploring student perceptions of empathy development during medical school - A phenomenological study.
Patient education and counseling
Patient Educ Couns
105
12
10.1016/j.pec.2022.08.015
eng
2,022
12
null
2,022
8
29
[OBJECTIVE] Empathy is an essential attribute of a good doctor. There are multiple dimensions to empathy, yet many curricula are limited to empathy display. This study's aim was to understand the relationship between teaching, learning and development of empathy from the perspective of medical students. [METHODS] A qua...
Communication; Empathy; Learning; Medical education; Medical-students; Phenomenology; Physician-patient relationship; Teaching
1
168
Medicine
Medicine
2,022
36,064,310
Identification of COX4I2 as a hypoxia-associated gene acting through FGF1 to promote EMT and angiogenesis in CRC.
Cellular molecular biology letters
Cell Mol Biol Lett
27
1
10.1186/s11658-022-00380-2
eng
2,022
9
5
2,022
9
5
[BACKGROUND] Current evidence suggests that the hypoxic tumor microenvironment further aggravates tumor progression, leading to poor therapeutic outcomes. There is as yet no biomarker capable of evaluating the hypoxic state of the tumor. The cytochrome c oxidase (COX) subunit is crucial to the mitochondrial respiratory...
Angiogenesis; COX4I2; Cancer-associated fibroblasts; Colorectal cancer; Fibroblast growth factor 1
null
null
null
null
null
36,064,129
Questionable Long-Term Results of the Extended Provisional Extension to Induce Complete Attachment (E-PETTICOAT) Technique in the Management of Chronic Type B Aortic Dissection.
Annals of vascular surgery
Ann Vasc Surg
89
null
10.1016/j.avsg.2022.08.012
eng
2,023
2
null
2,022
9
5
[BACKGROUND] Published interim results of the extended provisional extension to induce complete attachment (e-PETTICOAT) technique suggested favorable remodeling in chronic type B Aortic Dissection (cTBAD). This report presents long-term results of the e-PETTICOAT technique for the management of cTBAD (without aneurysm...
null
0.616
87
Cardiology and Cardiovascular Medicine; Medicine; Surgery
Medicine
2,023
36,062,283
Diagnostic Accuracy of the Apparent Diffusion Coefficient for Microvascular Invasion in Hepatocellular Carcinoma: A Meta-analysis.
Journal of clinical and translational hepatology
J Clin Transl Hepatol
10
4
10.14218/JCTH.2021.00254
eng
2,022
8
28
2,022
1
4
[BACKGROUND AND AIMS] Microvascular invasion (MVI) is a major risk factor for the early recurrence of hepatocellular carcinoma (HCC) and it seriously worsens the prognosis. Accurate preoperative evaluation of the presence of MVI could greatly benefit the treatment management and prognosis prediction of HCC patients. Th...
Diagnostic accuracy; Diffusion-weighted imaging; Hepatocellular carcinoma; Meta-analysis; Microvascular invasion
0.768
54
Hepatology
Medicine
2,022
36,062,194
Curcumin Inhibits Hyperandrogen-Induced IRE1α-XBP1 Pathway Activation by Activating the PI3K/AKT Signaling in Ovarian Granulosa Cells of PCOS Model Rats.
Oxidative medicine and cellular longevity
Oxid Med Cell Longev
2022
null
10.1155/2022/2113293
eng
2,022
null
null
2,022
8
24
[BACKGROUND] Hyperandrogenism is a common characteristic of polycystic ovary syndrome (PCOS). Long-term, continuous exposure to hyperandrogenic environments may cause excessive endoplasmic reticulum (ER) stress in ovarian granulosa cells (GCs). Curcumin is a polyphenol extracted from turmeric rhizomes which has several...
null
1.324
170
Biochemistry; Medicine; Aging; Cell Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,062,096
Association of family wellbeing with forwarding and verifying COVID-19-related information, and mediation of family communication quality.
Frontiers in public health
Front Public Health
10
null
10.3389/fpubh.2022.948955
eng
2,022
null
null
2,022
8
17
[OBJECTIVE] We assessed the associations of family wellbeing with verifying and subsequently forwarding COVID-19-related information to family members and the mediating effect of the quality of family communication on these associations among Chinese adults in Hong Kong. [METHODS] Under the Jockey Club SMART Family-Lin...
COVID-19; fact-check; family wellbeing; information overload; information sharing; misinformation
1.125
119
Public Health, Environmental and Occupational Health
Medicine
2,022
36,061,378
Genotypes and clinical intervention of patients with neurofibromatosis type 1 associated dystrophic scoliosis.
Frontiers in pediatrics
Front Pediatr
10
null
10.3389/fped.2022.918136
eng
2,022
null
null
2,022
8
18
[OBJECTIVE] To analyze the genotypic characteristics of patients with neurofibromatosis type 1 (NF1) associated dystrophic scoliosis and to summarize the outcomes of the surgical treatment of these patients. [METHODS] Exome sequencing (ES) combined with multiplex ligation-dependent probe amplification (MLPA) was used f...
NF1; dystrophic scoliosis; exome sequencing; growing-rod surgery; mutation detection rate; posterior spinal fusion
0.798
83
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,061,284
Cooperative Extension professionals' knowledge and attitudes toward the opioid epidemic: Implications for capacity development and outreach.
Frontiers in psychiatry
Front Psychiatry
13
null
10.3389/fpsyt.2022.958335
eng
2,022
null
null
2,022
8
17
[INTRODUCTION] Worsening of the opioid epidemic amplifies calls for involvement of the nationwide Cooperative Extension System (Extension) in addressing this crisis. Understanding knowledge and attitudes among Extension professionals who directly interact with communities is critical given identified needs for increase...
Cooperative Extension; Extension educators; capacity development; needs assessment; opioid crisis; opioid epidemic; professional development; substance use prevention
1.222
134
Psychiatry and Mental Health
Medicine
2,022
36,061,279
Psychological distress and its influencing factors among psychiatric nurses in China: A cross-sectional study.
Frontiers in psychiatry
Front Psychiatry
13
null
10.3389/fpsyt.2022.948786
eng
2,022
null
null
2,022
8
17
[BACKGROUND] Psychiatric nurses often face abuse, attacks, escape, suicides, and other situations related to the care of patients with mental disorders, which are more likely to induce psychological distress. [AIMS] This study aimed to examine the relationship between coping styles and psychological distress among Chin...
China; coping styles; psychiatric nurse; psychological distress; sleep quality
1.222
134
Psychiatry and Mental Health
Medicine
2,022
36,060,523
Animal Brucellosis: Seropositivity rates, Isolation and Molecular Detection in Southern and Central Ethiopia.
Veterinary medicine (Auckland, N.Z.)
Vet Med (Auckl)
13
null
10.2147/VMRR.S372455
eng
2,022
null
null
2,022
8
27
[INTRODUCTION] Brucellosis is a neglected bacterial zoonosis with serious veterinary and public health importance throughout the world. A cross-sectional study on animal brucellosis was conducted aiming to estimate seroprevalence and molecular detection. [METHODS] Blood samples were collected from a total of 4274 indiv...
Brucella melitensis; camel; neglected bacterial diseases; zoonosis
0.103
23
Small Animals
Veterinary
2,018
36,060,193
Development of an institutional protocol for percutaneous dilatational tracheostomy in critically ill COVID-19 patients: Initial experience.
Journal of anaesthesiology, clinical pharmacology
J Anaesthesiol Clin Pharmacol
38
Suppl 1
10.4103/joacp.joacp_495_21
eng
2,022
7
null
2,022
6
15
[BACKGROUND AND AIMS] Percutaneous dilatational tracheostomy (PDT) may improve the outcome in critically ill COVID-19 patients on mechanical ventilation. However, the timing of performing tracheostomy may be controversial, and it is an aerosol-generating procedure with a potential risk of viral exposure to healthcare w...
Coronavirus disease 2019; mechanical ventilation; percutaneous dilatational tracheostomy
0.41
48
Anesthesiology and Pain Medicine; Pharmacology, Toxicology and Pharmaceutics; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,060,124
Downregulation of miR-221-3p by LncRNA TUG1 Promoting the Healing of Closed Tibial Fractures in Mice.
BioMed research international
Biomed Res Int
2022
null
10.1155/2022/1624446
eng
2,022
null
null
2,022
8
26
[OBJECTIVE] To probe into the effect of LncRNA TUG1 on the healing of closed tibial fracture in mice. [METHODS] The closed tibial fracture model of mice was established, selecting the mouse osteoblast line MC3T3-E1, with the cells separated into four groups. The expression levels of TUG1 and miR-221-3p were determined ...
null
0.64
203
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,022
36,060,045
Factors Associated with 5-year Glaucomatous Progression in Glaucoma Suspect Eyes: A Retrospective Longitudinal Study.
Journal of current glaucoma practice
J Curr Glaucoma Pract
16
1
10.5005/jp-journals-10078-1350
eng
2,022
null
null
null
null
null
[PURPOSE] Using demographic, clinical, visual field, and optical coherence tomography (OCT) variables to study the association of 5-year glaucomatous progression in glaucoma suspect eyes. [PATIENTS AND METHODS] This is a retrospective longitudinal clinical study. Inclusion criteria consisted of glaucoma suspect eyes (i...
Glaucoma suspect; Glaucomatous progression; Ocular hypertension; Optical coherence tomography (OCT); Retinal nerve fiber layer (RNFL); Risk factors; Visual field; Visual field index
null
null
null
null
null
36,059,705
High expression of nectin-1 indicates a poor prognosis and promotes metastasis in hepatocellular carcinoma.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.953529
eng
2,022
null
null
2,022
8
18
[OBJECTIVES] Nectins are a new class of cell-adhesion molecules that play an important role in tumorigenesis and disease progression. The aim of this study was to investigate the prognostic and pathogenetic roles of nectins in hepatocellular carcinoma (HCC). [METHODS] The expression levels of the nectin family in HCC a...
cell proliferation; hepatocellular carcinoma; metastasis; nectin-1; prognostic
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,059,138
Population pharmacokinetic/pharmacodynamic study suggests continuous infusion of ceftaroline daily dose in ventilated critical care patients with early-onset pneumonia and augmented renal clearance.
The Journal of antimicrobial chemotherapy
J Antimicrob Chemother
77
11
10.1093/jac/dkac299
eng
2,022
10
28
null
null
null
[OBJECTIVES] Ceftaroline could be suitable to treat early-onset ventilator-associated pneumonia (VAP) because of its antibacterial spectrum. However, augmented renal clearance (ARC) is frequent in ICU patients and may affect ceftaroline pharmacokinetics and efficacy. The objective of the study was to explore the impact...
null
1.382
229
Infectious Diseases; Microbiology; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,115,566
Major Genetic Motifs in Pituitary Adenomas: A Practical Literature Update.
World neurosurgery
World Neurosurg
169
null
10.1016/j.wneu.2022.09.036
eng
2,023
1
null
2,022
9
14
[BACKGROUND] The literature includes many studies examining the genetic abnormalities that influence pituitary adenomas (PAs). We aimed to state the collective knowledge on the genetic underpinnings of PAs by organizing, summarizing, and consolidating the literature to serve as a comprehensive review for scientists and...
Familial; Genetics; Germline; Mutation; Pituitary adenoma; Sporadic
0.654
123
Neurology; Surgery
Medicine
2,023
36,115,256
Age, GH/IGF-1 levels, tumor volume, T2 hypointensity, and tumor subtype rather than proliferation and invasion are all reliable predictors of biochemical response to somatostatin analogue therapy in patients with acromegaly: A clinicopathological study.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
Growth Horm IGF Res
67
null
10.1016/j.ghir.2022.101502
eng
2,022
12
null
2,022
9
9
[PURPOSE] To determine whether biochemical responses to long-acting forms of first-generation somatostatin analogue (SSA) therapy in patients with acromegaly could be predicted from baseline and postoperative hormone concentrations, and tumor radiological and histopathological characteristics. [METHODS] A total of 68 p...
Acromegaly; Biochemical response; Growth hormone; Insulin-like growth factor-1; Somatostatin analogues
null
null
null
null
null
36,115,177
Intraoperative changes in medial joint gap after posterior femoral condylar resection, posterior osteophyte removal, and femoral component placement during primary total knee arthroplasty.
The Knee
Knee
39
null
10.1016/j.knee.2022.08.008
eng
2,022
12
null
2,022
9
14
[BACKGROUND] "Mid-flexion stability" is important for superior patient satisfaction following total knee arthroplasty (TKA). Thus, it is important to control medial joint gap intraoperatively as a countermeasure. However, reports on the precise intraoperative changes in medial joint gap during TKA are scarce. This stud...
Component gap; Medial joint gap; Posterior clearance; Posterior condylar offset; Pre-cut technique; Total knee arthroplasty
0.782
98
Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,022
36,115,077
CT radiomics combined with clinical variables for predicting the overall survival of hepatocellular carcinoma patients after hepatectomy.
Translational oncology
Transl Oncol
26
null
10.1016/j.tranon.2022.101536
eng
2,022
12
null
2,022
9
15
[PURPOSE] To establish a model for assessing the overall survival (OS) of the hepatocellular carcinoma (HCC) patients after hepatectomy based on the clinical and radiomics features. [METHODS] This study recruited a total of 267 patients with HCC, which were randomly divided into the training (N = 188) and validation (N...
Hepatectomy; Hepatocellular carcinoma; Prognosis; Radiomics
1.15
78
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,115,011
Determinants of COVID-19 vaccine uptake among healthcare professionals and the general population in Cyprus: A web-based cross-sectional survey.
Journal of evaluation in clinical practice
J Eval Clin Pract
28
6
10.1111/jep.13764
eng
2,022
12
null
2,022
9
17
[OBJECTIVE] This study aims to examine the factors influencing COVID-19 vaccine uptake among healthcare professionals (HCPs) and the general population in Cyprus. [METHODS] A web-based cross-sectional study was conducted (November 2021-January 2022), using a self-administered, anonymous questionnaire to collect informa...
COVID-19; Cyprus; SARS-CoV-2; healthcare professionals; vaccination coverage; vaccination uptake
0.782
91
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,022
36,114,593
Real-world outcomes of cisplatin, capecitabine, and gemcitabine with either epirubicin (PEXG) or docetaxel (PDXG) as first-line palliative treatment in metastatic or unresectable locally advanced pancreatic adenocarcinoma.
Asia-Pacific journal of clinical oncology
Asia Pac J Clin Oncol
19
5
10.1111/ajco.13845
eng
2,023
10
null
2,022
9
16
[BACKGROUND] First-line palliative chemotherapy regimens in advanced pancreatic adenocarcinoma include triplet chemotherapy with 5-fluorouracil, oxaliplatin, and irinotecan, and the doublet of nab-paclitaxel plus gemcitabine. Use of triplet chemotherapy in real-world populations is limited by tolerability and nab-pacli...
PDXG; PEXG; pancreatic adenocarcinoma; pancreatic cancer
0.531
45
Medicine; Oncology
Medicine
2,023
36,114,514
The role of DNA demethylation in liver to pancreas transdifferentiation.
Stem cell research & therapy
Stem Cell Res Ther
13
1
10.1186/s13287-022-03159-6
eng
2,022
9
16
2,022
9
16
[BACKGROUND] Insulin producing cells generated by liver cell transdifferentiation, could serve as an attractive source for regenerative medicine. The present study assesses the relationship between DNA methylation pTFs induced liver to pancreas transdifferentiation. [RESULTS] The transdifferentiation process is associa...
Cell replacement therapy for diabetes; DNA methylation; Epigenetic modifications; Liver; Pancreas; Pancreatic transcription factors; Transdifferentiation
null
null
null
null
null
36,114,476
Cranial fasciitis in children: clinicoradiology features and management.
BMC pediatrics
BMC Pediatr
22
1
10.1186/s12887-022-03610-w
eng
2,022
9
17
2,022
9
17
[BACKGROUND] Cranial fasciitis (CF) is a rare benign fibroproliferative lesion of the skull. To date, the summarized radiologic characteristics and the subtype of the disease have not been reported. our purpose was to summarize the characteristic clinicoradiology features and management of CF and to improve the knowled...
Children; Cranial fasciitis; Management; Tomography
0.742
106
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,114,087
The Impact of Sharing Drug Rebates at the Point of Sale on Out-of-Pocket Payments for Enrollees in Employer-Sponsored Insurance.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
Value Health
26
2
10.1016/j.jval.2022.08.001
eng
2,023
2
null
2,022
9
14
[OBJECTIVES] This study aimed to estimate the impact of sharing drug rebates at the point of sale on out-of-pocket spending by linking estimated rebates to administrative claims data for employer-sponsored insurance enrollees in 2018. [METHODS] We applied the drug rebate rate to the retail price of each brand name drug...
drug rebates; employer-sponsored insurance; out-of-pocket savings; patient affordability; premium
1.507
138
Health Policy; Medicine; Public Health, Environmental and Occupational Health
Medicine
2,023
36,113,983
Diagnosis of hepatocellular carcinoma based on salivary protein glycopatterns and machine learning algorithms.
Clinical chemistry and laboratory medicine
Clin Chem Lab Med
60
12
10.1515/cclm-2022-0715
eng
2,022
11
25
2,022
9
19
[OBJECTIVES] Hepatocellular carcinoma (HCC) is difficult to diagnose early and progresses rapidly, making it one of the most deadly malignancies worldwide. This study aimed to evaluate whether salivary glycopattern changes combined with machine learning algorithms could help in the accurate diagnosis of HCC. [METHODS] ...
glycopatterns; hepatocellular carcinoma; lectin microarrays; machine learning; saliva
1.266
127
Biochemistry; Clinical Biochemistry; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,113,381
Pancreatic fibrosis by extracellular volume fraction using Contrast-enhanced computed tomography and relationship with pancreatic cancer.
European journal of radiology
Eur J Radiol
156
null
10.1016/j.ejrad.2022.110522
eng
2,022
11
null
2,022
9
11
[PURPOSE] This study aimed to assess the relationship between pancreatic fibrosis measured by the extracellular volume fraction (ECV) using contrast-enhanced computed tomography (CT) and the histologic pancreatic fibrosis fraction and investigate the relationship between pancreatic fibrosis and pancreatic cancer. [METH...
Contrast Media; Diagnostic Imaging; Fibrosis; Multidetector Computed Tomography
0.939
139
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
36,113,192
Associations between muscle mass/strength and healthcare costs/use for patients with cancer: A systematic literature review.
Cancer treatment and research communications
Cancer Treat Res Commun
33
null
10.1016/j.ctarc.2022.100633
eng
2,022
null
null
2,022
9
9
[PURPOSE] To review published scientific evidence evaluating the potential associations between muscle mass/strength and healthcare use/costs for patients with cancer. [METHODS] In accordance with the predefined protocol for a systematic literature review, studies assessing potential associations between muscle mass/st...
Cancer; Healthcare costs; Muscle mass/strength; Systematic review
0.674
29
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,112,821
Newborn screening for propionic, methylmalonic acidemia and vitamin B12 deficiency. Analysis of 588,793 newborns.
Journal of pediatric endocrinology metabolism : JPEM
J Pediatr Endocrinol Metab
35
10
10.1515/jpem-2022-0340
eng
2,022
10
26
2,022
9
19
[OBJECTIVES] We present the results of our experience in the diagnosis and follow up of the positive cases for propionic, methylmalonic acidemias and cobalamin deficiencies (PA/MMA/MMAHC) since the Expanded Newborn Screening was implemented in Madrid Region. [METHODS] Dried blood samples were collected 48 h after birth...
inborn error of metabolism; methymalonic acidemia; neonatal screening; propionic acidemia; tandem mass spectrometry; vitamin B12
null
null
null
null
null
36,112,570
Factors affecting patient satisfaction in refugee health centers in Turkey.
PloS one
PLoS One
17
9
10.1371/journal.pone.0274316
eng
2,022
null
null
2,022
9
16
[BACKGROUND] Turkey hosts an estimated 3.7 million Syrian refugees. Syrian refugees have access to free primary care provided through Refugee Health Centers(RHC). We aimed to determine factors that influence patient satisfaction in refugee health centers. [METHODS] The study was a cross-sectional quantitative study. A ...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,112,482
Systematic review and meta-analysis for 2023 clinical practice guidelines of the Japan Research Committee of the Ministry of Health, Labour, and Welfare for Intractable Vasculitis for the management of ANCA-associated vasculitis.
Modern rheumatology
Mod Rheumatol
33
5
10.1093/mr/roac114
eng
2,023
8
25
null
null
null
[OBJECTIVES] The objective of this study is to provide evidence for the revision of clinical practice guidelines for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis by the Japan Research Committee for Intractable Vasculitis. [METHODS] PubMed, CENTRAL, and the Japan Medical Abstracts S...
ANCA-associated vasculitis; GRADE system; granulomatosis with polyangiitis; microscopic polyangiitis; systematic review
0.727
71
Medicine; Rheumatology
Medicine
2,023
36,112,429
Assessment of height growth in Indian children using growth centiles and growth curves.
Annals of human biology
Ann Hum Biol
49
5-6
10.1080/03014460.2022.2107238
eng
2,022
9
null
null
null
null
[BACKGROUND] Growth centiles and growth curves are two ways to present child anthropometry; however, they differ in the type of data used, the method of analysis, the biological parameters fitted and the form of interpretation. [AIM] To fit and compare height growth centiles and curves in Indian children. [SUBJECTS AND...
GAMLSS; Height centiles; India; SITAR; growth curves
0.453
70
Epidemiology; Genetics; Physiology; Public Health, Environmental and Occupational Health; Aging
Biochemistry, Genetics and Molecular Biology; Medicine
2,022