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36,149,506
Clinical evaluation of percutaneous endovascular radiofrequency ablation for portal vein tumor thrombus: experience in 120 patients.
Surgical endoscopy
Surg Endosc
37
2
10.1007/s00464-022-09639-3
eng
2,023
2
null
2,022
9
23
[BACKGROUND] Portal vein tumor thrombosis (PVTT) secondary to primary liver carcinoma (PLC) is commonly associated with poor prognosis and poses great challenge. This study was to evaluate the efficacy and safety of percutaneous endovascular radiofrequency ablation (RFA) in treatment of PVTT. [METHODS] Consecutive pati...
Overall survival; Portal vein; Primary liver carcinoma; Radiofrequency ablation; Thrombus
1.12
178
Surgery
Medicine
2,023
36,149,477
A novel magnetic resonance imaging scoring system for active and chronic changes in children and adolescents with juvenile idiopathic arthritis of the hip.
Pediatric radiology
Pediatr Radiol
53
3
10.1007/s00247-022-05502-8
eng
2,023
3
null
2,022
9
23
[BACKGROUND] Hip involvement predicts severe disease in juvenile idiopathic arthritis (JIA) and is accurately assessed by MRI. However, a child-specific hip MRI scoring system has not been validated. [OBJECTIVE] To test the intra- and interobserver agreement of several MRI markers for active and chronic hip changes in ...
Adolescents; Children; Hip; Inflammation; Joint damage; Juvenile idiopathic arthritis; Magnetic resonance imaging; Scoring system; Young adults
0.68
104
Pediatrics, Perinatology and Child Health; Radiology, Nuclear Medicine and Imaging
Medicine
2,023
36,149,413
Genetic drivers of Cushing's disease: Frequency and associated phenotypes.
Genetics in medicine : official journal of the American College of Medical Genetics
Genet Med
24
12
10.1016/j.gim.2022.08.021
eng
2,022
12
null
2,022
9
23
[PURPOSE] Cushing's disease (CD) is often explained by a single somatic sequence change. Germline defects, however, often go unrecognized. We aimed to determine the frequency and associated phenotypes of genetic drivers of CD in a large cohort. [METHODS] We studied 245 unrelated patients with CD (139 female, 56.7%), in...
Corticotropinoma; Exome sequencing; Germline variant; Pituitary tumor
2.745
167
Genetics; Medicine
Medicine
2,022
36,149,249
Does it fit better? Measures of physical activity among adolescents in relation to health indicators.
European journal of public health
Eur J Public Health
32
6
10.1093/eurpub/ckac138
eng
2,022
11
29
null
null
null
[BACKGROUND] Measuring physical activity (PA) is one of the pillars of successful health promotion; however, we struggle to find a tool enabling the identification of risk groups. The current standard approach of assessing moderate-to-vigorous physical activity (MVPA) every day does this inadequately. The aim of this s...
null
1.028
118
Public Health, Environmental and Occupational Health
Medicine
2,022
36,149,197
Serum immunoglobulins, C-reactive protein, and trace element level in preeclamptic Nigerian subjects.
Nigerian journal of clinical practice
Niger J Clin Pract
25
9
10.4103/njcp.njcp_1455_21
eng
2,022
9
null
null
null
null
[BACKGROUND] The mechanism involved in the pathogenesis of preeclampsia (PE) remains uncertain, and the research into a better understanding, its possible prediction, and subsequent prevention continues. [AIM] This study evaluated changes in serum immunoglobulins (IgG, IgA, and IgM), C-reactive protein, and trace eleme...
Immunoglobulin; Nigeria; preeclampsia; trace element
0.277
39
Medicine
Medicine
2,022
36,149,090
Complement dysregulation and Alzheimer's disease in Down syndrome.
Alzheimer's & dementia : the journal of the Alzheimer's Association
Alzheimers Dement
19
4
10.1002/alz.12799
eng
2,023
4
null
2,022
9
23
[INTRODUCTION] Down syndrome (DS) is associated with immune dysregulation and a high risk of early onset Alzheimer's disease (AD). Complement is a key part of innate immunity and driver of pathological inflammation, including neuroinflammation in AD. Complement dysregulation has been reported in DS; however, the patter...
Alzheimer's disease; Down syndrome; complement system; dementia; immune dysregulation
null
null
null
null
null
36,148,690
Establishing UK research priorities in smell and taste disorders: A James Lind alliance priority setting partnership.
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
Clin Otolaryngol
48
1
10.1111/coa.13985
eng
2,023
1
null
2,022
10
2
[OBJECTIVES] To determine the top 10 research priorities in Smell and Taste Disorders (SATD). [DESIGN] After steering group was established, an electronic survey was disseminated to determine the list of questions. After removing out-of-scope responses, the remainder were consolidated to create summary questions. A lit...
advocacy; anosmia; hyposmia; olfactory disorders; parosmia; phantosmia
0.646
84
Medicine; Otorhinolaryngology
Medicine
2,023
36,148,566
Analysis of Differences in DNA Damage and Repair Efficacy in Lymphocytes of Patients with Bipolar Disorder.
Turk psikiyatri dergisi = Turkish journal of psychiatry
Turk Psikiyatri Derg
33
3
10.5080/u26116
eng
2,022
null
null
null
null
null
[OBJECTIVE] The aim of this study was to determine DNA damage during euthymic and attack periods, and the oxidative metabolism states that may cause this damage in the pathophysiology of bipolar disorder. The role of DNA repair mechanisms in this process was also investigated. [METHOD] The study included a total of 90 ...
Bipolar disorder; DNA damage DNA repair.; oxidative stress
null
null
null
null
null
36,148,157
The Prognostic Value of Serum HBV-RNA during Hepatitis B Virus Infection is Related to Acute-on-Chronic Liver Failure.
Canadian journal of gastroenterology & hepatology
Can J Gastroenterol Hepatol
2022
null
10.1155/2022/8422242
eng
2,022
null
null
2,022
9
13
[BACKGROUND] Serum HBV-RNA levels can predict antiviral response in chronic hepatitis B (CHB) patients; however, its role in HBV-related ACLF (HBV-ACLF) remains unclear. Here, we determined its implications for HBV-ACLF. [METHODS] Baseline serum HBV-RNA levels were retrospectively detected in HBV-ACLF and CHB patients....
null
null
null
null
null
null
36,147,980
Effects of adjunctive pimavanserin and current antipsychotic treatment on QT interval prolongation in patients with schizophrenia.
Frontiers in psychiatry
Front Psychiatry
13
null
10.3389/fpsyt.2022.892199
eng
2,022
null
null
2,022
9
6
[BACKGROUND] Pimavanserin prolongs the QT interval, with mean increases in corrected QT (QTc) of 5-8 ms, and is currently being investigated for the treatment of negative symptoms of schizophrenia. [OBJECTIVES] To assess QT interval prolongation in 3 studies investigating once-daily pimavanserin as an adjunct to curren...
QT interval; adjunctive therapy; antipsychotics; pimavanserin; schizophrenia
1.222
134
Psychiatry and Mental Health
Medicine
2,022
36,147,697
Percutaneous full-endoscopic uniportal decompression for the treatment of symptomatic idiopathic lumbar spinal epidural lipomatosis: Technical note.
Frontiers in surgery
Front Surg
9
null
10.3389/fsurg.2022.894662
eng
2,022
null
null
2,022
9
6
[BACKGROUND] Lumbar spinal epidural lipomatosis (SEL) is a rare condition characterized by an excessive accumulation of adipose tissue within the spinal canal, compressing the dura sac and/or nerve roots. When conservative treatments fail and clinical symptoms progress quickly and seriously, surgical decompression shou...
full-endoscopic; minimally invasive surgery; percutaneous; spinal epidural lipomatosis; uniportal
0.459
48
Surgery
Medicine
2,022
36,147,647
Meta-Analysis of the Effects of Three-Dimensional Visualized Medical Techniques Hepatectomy for Liver Cancer with and without the Treatment of Sorafenib.
Evidence-based complementary and alternative medicine : eCAM
Evid Based Complement Alternat Med
2022
null
10.1155/2022/4507673
eng
2,022
null
null
2,022
9
13
[BACKGROUND] The application of medical image three-dimensional (3D) reconstruction technology can provide intuitive 3D image data support for accurate preoperative evaluation, surgical planning, and operation safety. However, there is still a lack of high-quality evidence to support whether 3D reconstruction technolog...
null
null
null
null
null
null
36,147,610
Prospective Optimization of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration Lymph Node Assessment for Lung Cancer: Three Needle Agitations Are Noninferior to 10 Agitations for Adequate Tumor Cell and DNA Yield.
JTO clinical and research reports
JTO Clin Res Rep
3
10
10.1016/j.jtocrr.2022.100403
eng
2,022
10
null
2,022
8
30
[INTRODUCTION] Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS TBNA) is an important means of obtaining a tissue for advanced lung cancer. Optimizing the EBUS TBNA needling technique is important to maintain procedural simplicity and maximize sample quality for emerging molecular diagnostics. [ME...
Cytology smears; EBUS TBNA; Lung cancer; Molecular testing
0.923
25
Oncology; Pulmonary and Respiratory Medicine
Medicine
2,022
36,147,547
Development of Injectable and Biodegradable Needle-Type Starch Implant for Effective Intratumoral Drug Delivery and Distribution.
International journal of nanomedicine
Int J Nanomedicine
17
null
10.2147/IJN.S370194
eng
2,022
null
null
2,022
9
16
[INTRODUCTION] Compared to intravenous administration, intratumoral drug administration enables the direct delivery of drugs to tumors and mitigates the systemic absorption of drugs and associated drug-induced side effects. However, intratumoral drug administration presents several challenges. The high interstitial flu...
implant; intratumoral drug administration; photothermal therapy; starch; uniform drug distribution
1.111
193
Bioengineering; Biomaterials; Biophysics; Drug Discovery; Medicine; Organic Chemistry; Pharmaceutical Science; Nanoscience and Nanotechnology
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Materials Science; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,147,448
Transcutaneous Vagus Nerve Stimulation Combined with Rehabilitation Training in the Intervention of Upper Limb Movement Disorders After Stroke: A Systematic Review.
Neuropsychiatric disease and treatment
Neuropsychiatr Dis Treat
18
null
10.2147/NDT.S376399
eng
2,022
null
null
2,022
9
16
[INTRODUCTION] Stroke often leaves behind a wide range of functional impairments, of which limb movement disorders are more common. Approximately 85% of patients have varying degrees of upper limb motor impairment. In recent years, transcutaneous vagus nerve stimulation combined with rehabilitation training has been gr...
TVNS; meta-analysis; motor function; stroke; systematic review
0.789
98
Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience
2,022
36,147,398
Non-radiation and non-drug-induced maxillary osteomyelitis: Study of underlying risk factors, presentation, management and treatment outcomes.
Medical journal, Armed Forces India
Med J Armed Forces India
78
Suppl 1
10.1016/j.mjafi.2020.06.008
eng
2,022
9
null
2,021
2
21
[BACKGROUND] Osteomyelitis of the jawbone is mostly secondary to radiation exposure or bone remodelling drugs, with the mandible being commonly involved. Maxillary osteomyelitis risk is low owing to its high vascularity. This study was undertaken to evaluate risk factors, presentation, management and outcomes of maxill...
Diabetes; Jawbone; Mucormycosis; Necrosis; Osteonecrosis; Tooth extraction
0.327
40
Medicine
Medicine
2,022
36,147,174
An extensive surgical resection in stage T4 small cell lung cancer with cardiac invasion: A case report and literature review.
Annals of medicine and surgery (2012)
Ann Med Surg (Lond)
81
null
10.1016/j.amsu.2022.104448
eng
2,022
9
null
2,022
8
19
[INTRODUCTION AND IMPORTANCE] We report a rare case of a patient with a mass involving both the hilum and the heart, but its specific nature could not be determined. SCLC was confirmed by postoperative pathology. It revealed that radical surgical resection for T4 SCLC should be considered an important part of multimoda...
AFP, alpha fetoprotein; CT, computed tomography; Cardiac invasion; Cardiac tumour; ECG, electrocardiogram; FNA, Fine needle aspiration; Left atrium; Multi-modality treatment; NSCLC, non-small cell lung carcinoma; PET, Positron emission tomography; PSM, propensity score matching; SCLC; SCLC, small cell lung carcinoma; S...
null
null
null
null
null
36,147,144
Pre-Cerclage cervical length predicts long-term pregnancy sustenance: A case-control study.
Annals of medicine and surgery (2012)
Ann Med Surg (Lond)
81
null
10.1016/j.amsu.2022.104467
eng
2,022
9
null
2,022
8
25
[BACKGROUND] This study aimed to assess a predictor of long-term pregnancy sustenance post cervical cerclage in women with or without a medical history of cervical insufficiency. [MATERIALS AND METHODS] We included pregnant women who underwent cerclage at 12-25 weeks gestation in four perinatal medical centers between ...
Cerclage; Cervical length; Preterm birth
null
null
null
null
null
36,147,135
Trans-pedal access for endovascular revascularization in complex infra-popliteal lesions in critically ischemic limb: A cohort study.
Annals of medicine and surgery (2012)
Ann Med Surg (Lond)
81
null
10.1016/j.amsu.2022.104215
eng
2,022
9
null
2,022
7
31
[BACKGROUND] critical limb ischemia is one of the most challenging cases we face nowadays with high risk for amputation, retrograde trans-pedal angioplasty offers an alternative technique after failure of traditional ante-grade angioplasty. [PATIENTS AND METHODS] 96 patients underwent trans-pedal or trans-tibial retrog...
Critical limb ischemia; Retrograde angioplasty; Trans-pedal access
null
null
null
null
null
36,147,113
Prenatal diagnosis of rare cloacal exstrophy: A case report.
Annals of medicine and surgery (2012)
Ann Med Surg (Lond)
81
null
10.1016/j.amsu.2022.104436
eng
2,022
9
null
2,022
8
17
[INTRODUCTION AND IMPORTANCE] Cloacal Exstrophy (CE) is a rare congenital birth defect. A correct prenatal diagnosis of CE is rarely made, even when congenital abnormalities are suspected on prenatal ultrasound examination. [CASE PRESENTATION] We report a case of CE with an abdominal defect about 5.31 cm in diameter se...
Case report; Cloacal exstrophy; Omphalocele; Prenatal diagnosis; Ultrasound
null
null
null
null
null
36,143,205
The Effect of SARS-CoV-2 Vaccination on B-Cell Phenotype in Systemic Sclerosis Patients.
Journal of personalized medicine
J Pers Med
12
9
10.3390/jpm12091420
eng
2,022
8
31
2,022
8
31
[OBJECTIVE] to assess the influence of SARS-CoV-2 mRNA vaccine on B-cell phenotypes in systemic sclerosis (SSc). [METHODS] peripheral blood B-cell subpopulations were evaluated before (t1) and 3 months (t3) after the second dose of vaccine in 28 SSc patients. Peripheral blood B-cell subpopulations were evaluated in 21 ...
B cells; COVID-19; humoral response; mRNA vaccine; systemic sclerosis
0.665
62
Medicine
Medicine
2,022
36,141,850
A Systematic Review of Recreational Nitrous Oxide Use: Implications for Policy, Service Delivery and Individuals.
International journal of environmental research and public health
Int J Environ Res Public Health
19
18
10.3390/ijerph191811567
eng
2,022
9
14
2,022
9
14
[BACKGROUND] Nitrous oxide (N2O) is a dissociative anaesthetic that is sometimes used recreationally. The prevalence of N2O use is difficult to quantify but appears to be increasing. Research on N2O harms and application of harm reduction strategies are limited. The aim of this mixed method systematic review was to col...
N2O; drug use; harm reduction; health risks; nangs; nitrous oxide; psychological harm; substance addiction; systematic review
0.828
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,022
36,140,501
Three-Dimensional Heads-Up vs. Standard Operating Microscope for Cataract Surgery: A Systematic Review and Meta-Analysis.
Diagnostics (Basel, Switzerland)
Diagnostics (Basel)
12
9
10.3390/diagnostics12092100
eng
2,022
8
30
2,022
8
30
[BACKGROUND] The surgical time duration, the postoperative best-corrected visual acuity (BCVA), and the incidence rate of intraoperative complications, alongside the vision and posturing parameters, were estimated by systematic review and meta-analysis to compare the three-dimensional (3D) heads-up visualization system...
3D Heads-up surgery; Artevo 800; Ngenuity; TrueVision; cataract surgery
0.67
81
Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology
2,022
36,140,411
The Role of Intraamygdaloid Oxytocin and D2 Dopamine Receptors in Reinforcement in the Valproate-Induced Autism Rat Model.
Biomedicines
Biomedicines
10
9
10.3390/biomedicines10092309
eng
2,022
9
16
2,022
9
16
[BACKGROUND] autism spectrum disorder (ASD) is a neurodevelopmental disorder affecting around 1 out of 68 children and its incidence shows an increasing tendency. There is currently no effective treatment for ASD. In autism research, the valproate (VPA)-induced autism rodent model is widely accepted. Our previous resul...
amygdala; autism; dopamine; oxytocin; place preference; reinforcement; valproate
0.897
85
Medicine; Biochemistry, Genetics and Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,139,746
Can Photobiomodulation Therapy (PBMT) Minimize Exercise-Induced Oxidative Stress? A Systematic Review and Meta-Analysis.
Antioxidants (Basel, Switzerland)
Antioxidants (Basel)
11
9
10.3390/antiox11091671
eng
2,022
8
27
2,022
8
27
[UNLABELLED] Oxidative stress induced by exercise has been a research field in constant growth, due to its relationship with the processes of fatigue, decreased production of muscle strength, and its ability to cause damage to the cell. In this context, photobiomodulation therapy (PBMT) has emerged as a resource capabl...
exercise; laser therapy; oxidative damage; phototherapy; reactive species
1.084
133
Biochemistry; Clinical Biochemistry; Food Science; Physiology; Cell Biology; Molecular Biology
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
2,022
36,139,641
Real-World Outcomes and Treatments Patterns Prior and after the Introduction of First-Line Immunotherapy for the Treatment of Metastatic Non-Small Cell Lung Cancer.
Cancers
Cancers (Basel)
14
18
10.3390/cancers14184481
eng
2,022
9
15
2,022
9
15
[BACKGROUND] This study provides insights into the treatment use and outcomes of metastatic non-small cell lung cancer (NSCLC) patients in a real-world setting prior to and after the availability of immuno-oncology (IO) regimens in the first line (1L). [METHODS] Metastatic NSCLC patients, who initiated systemic 1L anti...
cancer immunotherapy; first-line treatment; immune checkpoint inhibitors (ICIs); non-small cell lung cancers (NSCLC); observational study; overall survival (OS); real-world evidence; real-world progression-free survival (rwPFS)
1.312
157
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,139,002
Determining Whether Sex and Zygosity Modulates the Association between APOE4 and Psychosis in a Neuropathologically-Confirmed Alzheimer's Disease Cohort.
Brain sciences
Brain Sci
12
9
10.3390/brainsci12091266
eng
2,022
9
19
2,022
9
19
[BACKGROUND] The APOE4 allele is a genetic risk factor for developing late-onset Alzheimer's disease (AD). Previous work by our group revealed that female APOE4 homozygotes with Lewy body (LB) pathology were more likely to experience psychosis compared to female APOE4 non-carriers, whereas in males there was no APOE4 d...
APOE; Lewy body; neuropsychiatric; psychosis
0.752
78
Neuroscience
Neuroscience
2,022
36,138,874
A Metabolic Plasticity-Based Signature for Molecular Classification and Prognosis of Lower-Grade Glioma.
Brain sciences
Brain Sci
12
9
10.3390/brainsci12091138
eng
2,022
8
26
2,022
8
26
[BACKGROUND] Glioma is one of the major health problems worldwide. Biomarkers for predicting the prognosis of Glioma are still needed. [METHODS] The transcriptome data and clinic information on Glioma were obtained from the CGGA, TCGA, GDC, and GEO databases. The immune infiltration status in the clusters was compared....
glioma; metabolic signature; prognosis
0.752
78
Neuroscience
Neuroscience
2,022
36,138,508
Priapism Produced by Penile Metastasis from Colon Cancer.
Archivos espanoles de urologia
Arch Esp Urol
75
6
10.56434/j.arch.esp.urol.20227506.84
eng
2,022
8
null
null
null
null
[INTRODUCTION AND OBJECTIVE] The penile metastasis is a rare clinical entity. The objective is to present the first documented case report of penile metastasis from right colon. [CLINICAL CASE] A case of a 78-year-old man who was diagnosed with penile metastasis from right colon. The patient came to our consultation co...
colon; metastasis; penile; priapism
null
null
null
null
null
36,138,502
Utilidad del Renograma Diurético tras la Pieloplastia en la Población Pediátrica. ¿Es Necesario de Rutina?
Archivos espanoles de urologia
Arch Esp Urol
75
6
10.56434/j.arch.esp.urol.20227506.78
eng
2,022
8
null
null
null
null
[PURPOSE] The diuretic renal scan (MAG3) continues being the gold standard to test the improvement of the urinary drainage after pyeloplasty. Recent researches suggest that there are certain parameters of ultrasound (US) that may indicate an adequate urinary drainage during the follow-up. Our aim is to prove if the mea...
anteroposterior diameter; pyeloplasty; renal scan; ureteropelvic junction obstruction
null
null
null
null
null
36,138,416
Semi-quantitative analysis of cannabinoids in hemp (Cannabis sativa L.) using gas chromatography coupled to mass spectrometry.
Journal of cannabis research
J Cannabis Res
4
1
10.1186/s42238-022-00161-w
eng
2,022
9
22
2,022
9
22
[BACKGROUND] Hemp (Cannabis sativa L.) is a producer of cannabinoids. These organic compounds are of increasing interest due to their potential applications in the medicinal field. Advances in analytical methods of identifying and quantifying these molecules are needed. [METHOD] This study describes a new method of can...
Cannabinoids; Extraction; GC-MS; Industrial hemp; Low-abundance; Trichomes
null
22
Complementary and Alternative Medicine; Health; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
2,022
36,138,368
Factors associated with duration of breastfeeding in women giving birth for the first time.
BMC pregnancy and childbirth
BMC Pregnancy Childbirth
22
1
10.1186/s12884-022-05038-7
eng
2,022
9
22
2,022
9
22
[OBJECTIVE] To examine maternal, psychosocial, and pregnancy factors associated with breastfeeding for at least 6 months in those giving birth for the first time. [METHODS] We performed a planned secondary analysis of an observational cohort study of 5249 women giving birth for the first time. Women were contacted at l...
Breastfeeding; Longevity; Nulliparous patients
1.034
122
Obstetrics and Gynecology
Medicine
2,022
36,137,912
An integrative review of clinician-administered comforting touch interventions and acute stress responses of preterm infants.
Journal of pediatric nursing
J Pediatr Nurs
67
null
10.1016/j.pedn.2022.08.020
eng
2,022
null
null
2,022
9
20
[PROBLEM] Preterm infants experience numerous stressors in the neonatal intensive care unit. Non-pharmacological interventions, including maternal comforting touch, reduce stress responses of preterm infants; however, the effects of clinician-administered comforting touch are unclear. The purpose of this integrative re...
Neonatal nursing; Pain management; Premature infant; Stress; Touch
0.566
78
Pediatrics
Nursing
2,022
36,137,741
Brain neuronal and glial damage during acute COVID-19 infection in absence of clinical neurological manifestations.
Journal of neurology, neurosurgery, and psychiatry
J Neurol Neurosurg Psychiatry
93
12
10.1136/jnnp-2022-329933
eng
2,022
12
null
2,022
9
22
[BACKGROUND] To assess whether SARS-CoV-2 infection may affect the central nervous system, specifically neurons and glia cells, even without clinical neurological involvement. [METHODS] In this single centre prospective study, serum levels of neurofilament light chain (sNfL) and glial fibrillar acidic protein (sGFAp) w...
COVID-19
3.178
244
Neurology; Psychiatry and Mental Health; Surgery
Medicine
2,022
36,137,614
Long-term outcomes of very early treated infantile-onset Pompe disease with short-term steroid premedication: experiences from a nationwide newborn screening programme.
Journal of medical genetics
J Med Genet
60
5
10.1136/jmg-2022-108675
eng
2,023
5
null
2,022
9
22
[BACKGROUND] Starting enzyme replacement therapy (ERT) before severe irreversible muscular damage occurs is important in infantile-onset Pompe disease (IOPD). This long-term follow-up study demonstrates our diagnostic and treatment strategies for IOPD and compares our clinical outcomes with those of other medical centr...
Disease Management; Early Diagnosis; Genetics, Medical; Pediatrics
1.69
194
Genetics; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,137,212
A Nonexercise Prediction of Peak Oxygen Uptake for Patients With Cardiovascular Disease: DATA FROM THE FITNESS REGISTRY AND THE IMPORTANCE OF EXERCISE INTERNATIONAL DATABASE (FRIEND).
Journal of cardiopulmonary rehabilitation and prevention
J Cardiopulm Rehabil Prev
43
2
10.1097/HCR.0000000000000722
eng
2,023
3
1
2,022
9
22
[PURPOSE] Nonexercise predictions of peak oxygen uptake (V˙ o2peak) are used clinically, yet current equations were developed from cohorts of apparently healthy individuals and may not be applicable to individuals with cardiovascular disease (CVD). Our purpose was to develop a CVD-specific nonexercise prediction equati...
null
null
null
null
null
null
36,137,124
Unilateral cathodal transcranial direct current stimulation over the parietal area modulates postural control depending with eyes open and closed.
PloS one
PLoS One
17
9
10.1371/journal.pone.0269145
eng
2,022
null
null
2,022
9
22
[OBJECTIVE] Cathodal transcranial direct current stimulation (C-tDCS) is generally assumed to inhibit cortical excitability. The parietal cortex contributes to multisensory information processing in the postural control system, and this processing is proposed to be different between the right and left hemispheres and s...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,137,119
Prevalence, causes, and factors associated with obstructed labour among mothers who gave birth at public health facilities in Mojo Town, Central Ethiopia, 2019: A cross-sectional study.
PloS one
PLoS One
17
9
10.1371/journal.pone.0275170
eng
2,022
null
null
2,022
9
22
[BACKGROUND] Obstructed labour is a type of abnormal labour that is one of the causes of obstetric complications such as maternal and fetal mortality and morbidity. Early detection is the key to reducing complications. [OBJECTIVE] This study aimed to assess the prevalence, causes, and factors associated with obstructed...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,136,762
Bioavailability and cardiovascular effects of adrenaline administered by Anapen 500 μg auto-injector in healthy volunteers.
British journal of clinical pharmacology
Br J Clin Pharmacol
89
3
10.1111/bcp.15545
eng
2,023
3
null
2,022
10
10
[AIMS] Anaphylaxis guidelines recommend intramuscular adrenaline, commonly 300 μg administered using an auto-injector device. However, overweight/obese patients may require a higher adrenaline dose for adequate cardiovascular (CV) response. This study evaluated the pharmacokinetics (PK) and pharmacodynamic (PD) CV prof...
Anapen; adrenaline; anaphylaxis; auto-injector; cardiovascular responses; pharmacodynamic; pharmacokinetic
1.046
176
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,136,443
I Smoke Alone: Indirect Effects of Solitary Cannabis Use on Negative Consequences Through Coping Motives.
Journal of studies on alcohol and drugs
J Stud Alcohol Drugs
83
5
10.15288/jsad.21-00200
eng
2,022
9
null
null
null
null
[OBJECTIVE] Using cannabis in solitary contexts is associated with greater cannabis use problems than using cannabis in social contexts. However, it remains unclear why solitary use predicts greater problems. Consistent with a social learning perspective, the current study examined whether cannabis use motives mediated...
null
1.115
141
Health; Psychiatry and Mental Health; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
2,022
36,136,437
The Typology of Alcohol Use Disorder: Latent Class Analyses of a Population-Based Swedish Sample.
Journal of studies on alcohol and drugs
J Stud Alcohol Drugs
83
5
10.15288/jsad.21-00409
eng
2,022
9
null
null
null
null
[OBJECTIVE] The purpose of this study was to clarify the clinical heterogeneity of alcohol use disorder (AUD) in a national Swedish sample of affected individuals using latent class analysis. [METHOD] Using a Swedish population-based sample of AUD cases ascertained from medical, criminal, and pharmacy registries (n = 2...
null
1.115
141
Health; Psychiatry and Mental Health; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
2,022
36,136,238
Diabetes Mellitus May Exacerbate Liver Injury in Patients with COVID-19: A Single-Center, Observational, Retrospective Study.
Diabetes therapy : research, treatment and education of diabetes and related disorders
Diabetes Ther
13
11-12
10.1007/s13300-022-01318-9
eng
2,022
12
null
2,022
9
22
[INTRODUCTION] The spread of coronavirus disease 2019 (COVID-19) is having a profound effect on global health. In this study, we investigated early predictors of severe prognosis from the perspective of liver injury and risk factors for severe liver injury in patients with COVID-19. [METHODS] We examined prognostic mar...
Aminotransferase; COVID-19; Diabetes mellitus; Fibrosis-4; Prognostic marker; SARS-CoV-2
1.039
59
Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,022
36,136,232
Rapid Onset and Sustained Efficacy of Lasmiditan Among Japanese Patients with Migraine: Prespecified Analyses of a Randomized Controlled Trial.
Neurology and therapy
Neurol Ther
11
4
10.1007/s40120-022-00403-2
eng
2,022
12
null
2,022
9
22
[INTRODUCTION] Rapid onset and sustained efficacy are important for acute migraine treatment. Global phase 3 trials have demonstrated the early onset and sustained efficacy of the 5-HT1F receptor agonist lasmiditan. In this prespecified analysis of the MONONOFU study, we assessed the onset and sustained efficacy of las...
Headache; Japan; Lasmiditan; Migraine disorders; Onset of action; Pain freedom; Sustained efficacy
0.923
41
Neurology; Neurology
Medicine; Neuroscience
2,022
36,135,178
Higher NADH Dehydrogenase [Ubiquinone] Iron-Sulfur Protein 8 (NDUFS8) Serum Levels Correlate with Better Insulin Sensitivity in Type 1 Diabetes.
Current issues in molecular biology
Curr Issues Mol Biol
44
9
10.3390/cimb44090266
eng
2,022
8
26
2,022
8
26
[OBJECTIVE] The aim of the study was to evaluate NADH dehydrogenase [ubiquinone] iron-sulfur protein 8 (NDUFS8) serum concentration as a marker of Complex I, and the relationship with insulin resistance in type 1 diabetes mellitus (T1DM). [DESIGN AND METHODS] Participants were adults with T1DM, recruited over the cours...
diabetes mellitus; insulin resistance; mitochondria
null
null
null
null
null
36,133,787
Potential Targets and Action Mechanism of Gastrodin in the Treatment of Attention-Deficit/Hyperactivity Disorder: Bioinformatics and Network Pharmacology Analysis.
Evidence-based complementary and alternative medicine : eCAM
Evid Based Complement Alternat Med
2022
null
10.1155/2022/3607053
eng
2,022
null
null
2,022
9
12
[OBJECTIVE] Gastrodin is a main medicinal component of traditional Chinese medicine (TCM) Gastrodia elata Blume (G. elata), presenting the potential for the treatment of attention-deficit/hyperactivity disorder (ADHD). However, the underlying targets and action mechanisms of the treatment have not been identified. [MET...
null
null
null
null
null
null
36,131,538
Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy.
Hepatology (Baltimore, Md.)
Hepatology
77
3
10.1002/hep.32800
eng
2,023
3
1
2,023
2
17
[BACKGROUND AND AIMS] In biliary atresia, serum bilirubin is commonly used to predict outcomes after Kasai portoenterostomy (KP). Infants with persistently high levels invariably need liver transplant, but those achieving normalized levels have a less certain disease course. We hypothesized that serum bile acid levels ...
null
null
null
null
null
null
36,131,367
Retinal neuroblast migration and ganglion cell layer organization require the cytoskeletal-interacting protein Mllt11.
Developmental dynamics : an official publication of the American Association of Anatomists
Dev Dyn
252
2
10.1002/dvdy.540
eng
2,023
2
null
2,022
10
4
[BACKGROUND] The vertebrate retina is an organized laminar structure comprised of distinct cell types populating three nuclear layers. During development, each retinal cell type follows a stereotypical temporal order of genesis, differentiation, and migration, giving rise to its stratified organization. Once born, the ...
Mllt11/Af1q; migration; retina; retinal lamination; retinogenesis
null
null
null
null
null
36,131,342
Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system.
Cardiovascular diabetology
Cardiovasc Diabetol
21
1
10.1186/s12933-022-01623-4
eng
2,022
9
21
2,022
9
21
[BACKGROUND] Post-acute sequelae of COVID-19 (PASC), also now known as long COVID, has become a major global health and economic burden. Previously, we provided evidence that there is a significant insoluble fibrin amyloid microclot load in the circulation of individuals with long COVID, and that these microclots entra...
Antibodies; Failed fibrinolysis; Kallikrein; Long COVID; Microclots; Platelet factor 4; Platelet hyperactivation; von Willebrand factor
2.361
121
Cardiology and Cardiovascular Medicine; Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,022
36,131,257
Association between cortisol and aging-related hippocampus volume changes in community-dwelling older adults: a 7-year follow-up study.
BMC geriatrics
BMC Geriatr
22
1
10.1186/s12877-022-03455-z
eng
2,022
9
21
2,022
9
21
[BACKGROUND] Identifying peripheral biomarkers related to modifiable risk factors to prevent dementia at an early stage will be extremely beneficial. We have been studying how older adults can maintain their mental health and continue to live in a familiar community. The aim of this study is to investigate the associat...
Cognitive function; Cortisol; Hippocampus; MRI; Voxel-based morphometry
1.127
112
Geriatrics and Gerontology
Medicine
2,022
36,131,225
Thoracic posterior spinal instrumented fusion vs. thoracic anterior spinal tethering for adolescent idiopathic scoliosis with a minimum of 2-year follow-up: a cost comparison of index and revision operations.
Spine deformity
Spine Deform
11
2
10.1007/s43390-022-00586-6
eng
2,023
3
null
2,022
9
21
[PURPOSE] To compare direct costs of index and revision operations of thoracic posterior spinal instrumented fusion (TPSIF) and thoracic anterior spinal tethering (TAST) for adolescent idiopathic thoracic scoliosis in children. [METHODS] Children (ages 11-18 years) who underwent TPSIF and TAST (2/2013-9/2019) were revi...
Adolescent idiopathic scolosis; Anterior vertebral body tethering; Direct costs; Posterior fusion; Reoperation; Revisions
0.798
41
Orthopedics and Sports Medicine
Medicine
2,023
36,130,707
A wide clinical spectrum of pulmonary affection in subjects with community-acquired Klebsiella pneumoniae liver abscess (CA-KPLA).
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
J Infect Chemother
29
1
10.1016/j.jiac.2022.09.011
eng
2,023
1
null
2,022
9
18
[BACKGROUND] Klebsiella pneumoniae is a major pathogen of bacterial liver abscess in Asia. Particularly, patients with community-acquired Klebsiella pneumoniae liver abscess (CA-KPLA) tend to have a higher risk of invasive infection and pulmonary is a common invasive infectious site, making it a global clinical crisis....
Antibiotic therapy; Community-acquired; Klebsiella pneumoniae liver abscess; Nomogram; Pulmonary affection
0.579
76
Infectious Diseases; Pharmacology; Microbiology
Medicine
2,023
36,130,655
Comparative transcriptome reveals the effect of IFITM1 on differential resistance to duck hepatitis A virus genotype 3 in Pekin ducks.
Virus research
Virus Res
322
null
10.1016/j.virusres.2022.198930
eng
2,022
12
null
2,022
9
18
[BACKGROUND] Duck viral hepatitis (DVH) has a significant economic impact on duck industry, and duck hepatitis A virus genotype 3 (DHAV-3) is the most prevalent pathogen of DVH in Asian duck industry. The detailed study connecting differentially expressed genes (DEGs) and the differential resistance to DHAV-3 have not ...
DHAV-3; Gene expression; IFITM1; Pekin duck; Transcriptome analysis
1.034
151
Cancer Research; Infectious Diseases; Virology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,022
36,130,413
Predictors of maternal knowledge on early childhood development in highly marginalized communities in Mexico: Implications for public policy.
Acta psychologica
Acta Psychol (Amst)
230
null
10.1016/j.actpsy.2022.103743
eng
2,022
10
null
2,022
9
18
[INTRODUCTION] Efforts to identify the predictors of maternal knowledge on Early Child Development (ECD) have proven inconclusive thus far, particularly with respect to socially deprived contexts in Low- and Middle-Income Countries (LMICs). We quantified the extent of ECD knowledge among mothers who were the primary ca...
Early childhood development; Maternal knowledge; Mexico; Poverty
0.64
116
Arts and Humanities; Developmental and Educational Psychology; Experimental and Cognitive Psychology; Medicine
Arts and Humanities; Medicine; Psychology
2,022
36,130,187
Associations of Immunogenicity and Reactogenicity After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA-1273 Vaccine in the COVE and TeenCOVE Trials.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Clin Infect Dis
76
2
10.1093/cid/ciac780
eng
2,023
1
13
null
null
null
[BACKGROUND] The reactogenicity and immunogenicity of coronavirus disease 2019 (COVID-19) vaccines are well studied. Little is known regarding the relationship between immunogenicity and reactogenicity of COVID-19 vaccines. [METHODS] This study assessed the association between immunogenicity and reactogenicity after 2 ...
SARS-CoV-2; immunogenicity; mRNA-1273; reactogenicity; solicited adverse reactions
3.308
398
Infectious Diseases; Microbiology
Medicine
2,023
36,130,093
Effects of habitat disturbance on the reproductive ecology of Arum pictum ssp. sagittifolium: from pollination to seedling recruitment.
Annals of botany
Ann Bot
130
6
10.1093/aob/mcac120
eng
2,022
12
16
null
null
null
[BACKGROUND AND AIMS] The loss of natural habitats may strongly affect the fitness of plants that depend on animals for reproduction. However, very little is known regarding the differential effects of habitat disturbance on the distinct phases of the reproductive cycle of plants, especially in non-rewarding species. [...
Arum pictum ssp. sagittifolium; Mediterranean ecosystems; bird dispersal; deceptive pollination; habitat loss; land-use changes; reproductive output; seed germination; seedling establishment
1.213
215
Plant Science
Agricultural and Biological Sciences
2,022
36,129,996
Glycemia Reduction in Type 2 Diabetes - Glycemic Outcomes.
The New England journal of medicine
N Engl J Med
387
12
10.1056/NEJMoa2200433
eng
2,022
9
22
null
null
null
[BACKGROUND] The comparative effectiveness of glucose-lowering medications for use with metformin to maintain target glycated hemoglobin levels in persons with type 2 diabetes is uncertain. [METHODS] In this trial involving participants with type 2 diabetes of less than 10 years' duration who were receiving metformin a...
null
26.015
1,231
Medicine
Medicine
2,022
36,129,904
Effects of neuromuscular gait modification strategies on indicators of knee joint load in people with medial knee osteoarthritis: A systematic review and meta-analysis.
PloS one
PLoS One
17
9
10.1371/journal.pone.0274874
eng
2,022
null
null
2,022
9
21
[OBJECTIVES] This systematic review aimed to determine the effects of neuromuscular gait modification strategies on indicators of medial knee joint load in people with medial knee osteoarthritis. [METHODS] Databases (Embase, MEDLINE, Cochrane Central, CINAHL and PubMed) were searched for studies of gait interventions a...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,129,804
Dietary Factors and Early-Onset Colorectal Cancer in the United States-an Ecologic Analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Cancer Epidemiol Biomarkers Prev
32
2
10.1158/1055-9965.EPI-22-0442
eng
2,023
2
6
null
null
null
[BACKGROUND] Incidence of early-onset colorectal cancer (EOCRC; e.g., diagnosed before age 50) in the United States has increased substantially since the 1990s but the underlying reasons remain unclear. [METHODS] We examined the ecologic associations between dietary factors and EOCRC incidence in adults aged 25-49 duri...
null
null
null
null
null
null
36,129,580
Fracture incidence in children and adolescents 0-19 years old in Mexico: a 12-year cross-sectional analysis.
Archives of osteoporosis
Arch Osteoporos
17
1
10.1007/s11657-022-01162-1
eng
2,022
9
21
2,022
9
21
[UNLABELLED] The objective was to know the behavior of fractures in Mexican children and adolescents. According to our study, fractures in Mexican male children and adolescents seem to be decreasing; however, we still need more national studies to know the possible causes of these fractures. [PURPOSE] To describe the t...
Adolescent; Age factors; Bone; Child; Epidemiology; Fractures; Incidence; Risk management
0.717
49
Orthopedics and Sports Medicine
Medicine
2,022
36,129,196
Prenatal exposure to a natural disaster and early development of psychiatric disorders during the preschool years: stress in pregnancy study.
Journal of child psychology and psychiatry, and allied disciplines
J Child Psychol Psychiatry
64
7
10.1111/jcpp.13698
eng
2,023
7
null
2,022
9
21
[BACKGROUND] Growing evidence shows an association between in utero exposure to natural disasters and child behavioral problems, but we still know little about the development of specific psychopathology in preschool-aged children. [METHODS] Preschool children (n = 163, mean age = 3.19, 85.5% racial and ethnic minoriti...
Natural disasters; anxiety; developmental psychopathology; disruptive behavior; sex differences
3.133
252
Developmental and Educational Psychology; Pediatrics, Perinatology and Child Health; Psychiatry and Mental Health
Medicine; Psychology
2,023
36,128,967
Recognition of early warning signs and symptoms - the first steps on the road to Autism Spectrum Disorder diagnosis.
Annali dell'Istituto superiore di sanita
Ann Ist Super Sanita
58
3
10.4415/ANN_22_03_07
eng
2,022
null
null
null
null
null
[OBJECTIVE] To identify developmental symptoms reported at firsts doctor visits by parents of children later diagnosed with Autism Spectrum Disorder (ASD). [DESIGN] Cohort study. [SETTING] The study was conducted in the Department of Psychiatry Research of "Prof. Dr. Alexandru Obregia" Clinical Psychiatry Hospital from...
null
null
null
null
null
null
36,128,941
How (where) Does Music Background Hamper Driver Behaviour?
Human factors
Hum Factors
66
4
10.1177/00187208221127939
eng
2,024
4
null
2,022
9
21
[OBJECTIVE] The current study examined the effects of music on Hazard Perception - a skill that serves as a proxy for safe driving. [BACKGROUND] There is contradictory evidence whether or not music engagement leads to decremented driver performance and compromises traffic safety. [METHOD] In the study, 36 participants ...
driver distraction; in-car music; models of driving; music effects; video-based hazard perception test
1.479
148
Applied Psychology; Behavioral Neuroscience; Human Factors and Ergonomics
Neuroscience; Psychology; Social Sciences
2,024
36,128,479
County-Level Characteristics Associated with Variation in ESKD Mortality in the United States, 2010-2018.
Kidney360
Kidney360
3
5
10.34067/KID.0007872021
eng
2,022
5
26
2,022
3
3
[BACKGROUND] Geographic and neighborhood-level factors, such as poverty and education, have been associated with an increased risk for incident ESKD, likelihood of receiving pre-ESKD care, and likelihood of receiving a transplant. However, few studies have examined whether these same factors are associated with ESKD mo...
United States; clinical nephrology; disparity; end stage kidney disease; epidemiology and outcomes; kidney disease; mortality; neighborhood; risk factors; socioeconomic
null
26
Medicine; Nephrology
Medicine
2,022
36,128,024
COVID-19 Vaccine Survey among Healthcare Workers. A Community Experience.
Spartan medical research journal
Spartan Med Res J
7
2
10.51894/001c.35628
eng
2,022
null
null
2,022
9
6
[INTRODUCTION] In December 2019, the coronavirus (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) made its first appearance in Wuhan, China with a pandemic declared by March 2020. As the death toll continued to rise, the Centers for Diseases Control and Prevention (CDC) recommended heal...
COVID-19; Covid-19 vaccination; Covid-19 vaccine Survey; Vaccine Hesitancy
null
null
null
null
null
36,127,932
Evaluation of ECG Repolarization Parameters in a Worker Cohort Working the Night Shift.
Journal of the Saudi Heart Association
J Saudi Heart Assoc
34
3
10.37616/2212-5043.1309
eng
2,022
null
null
2,022
8
15
[OBJECTIVES] Night Shift work is an increasingly common working order that affects human well-being and it is little known about its arrhythmic role in the cardiovascular system. We aimed to investigate the effect of working at night shifts on P-wave dispersion (Pd), QT and QTc dispersions (QTd, QTcd resp) on surface e...
Night work; P-wave dispersion; QTc dispersion; Shift work; Shift worker
0.247
25
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,127,775
Volumetric Absorptive Microsampling for the Therapeutic Drug Monitoring of Everolimus in Patients Who Have Undergone Liver Transplant.
Therapeutic drug monitoring
Ther Drug Monit
45
2
10.1097/FTD.0000000000001033
eng
2,023
4
1
null
null
null
[BACKGROUND] Therapeutic drug monitoring (TDM) of everolimus is required to prevent organ rejection in patients who have undergone transplant. Volumetric absorptive microsampling (VAMS) is a minimally invasive method for accurately collecting a small amount of blood from a patient's fingers. This study aimed to assess ...
null
0.591
105
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,127,751
Effect of Behcet's disease-associated oral ulcers on oral health related quality of life.
Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry
Spec Care Dentist
43
4
10.1111/scd.12782
eng
2,023
null
null
2,022
9
20
[AIM] The current study assessed the clinical characteristics of patients suffering from Behcet's disease (BD)-associated oral ulcers and investigated the effect of these oral ulcers on the oral health-related quality of life (OHRQoL). [METHODS] This study included BD patients suffering from active oral ulcers, defined...
Behcet's disease; OHIP-14; OHRQoL; composite index; oral ulcers; quality of life
0.366
51
Dentistry
Dentistry
2,023
36,127,750
Validation of the Achalasia Patient-Reported Outcomes Questionnaire.
Alimentary pharmacology & therapeutics
Aliment Pharmacol Ther
56
10
10.1111/apt.17230
eng
2,022
11
null
2,022
9
20
[BACKGROUND] Achalasia is a debilitating major motor disorder of the oesophagus. Hypervigilance and symptom-specific anxiety substantially impact dysphagia symptom reporting, and quality of life is a critical patient outcome. Earlier achalasia symptom scales did not consider these constructs in their psychometric devel...
null
null
null
null
null
null
36,127,735
DNA methylation underpins the epigenomic landscape regulating genome transcription in Arabidopsis.
Genome biology
Genome Biol
23
1
10.1186/s13059-022-02768-x
eng
2,022
9
20
2,022
9
20
[BACKGROUND] It is challenging to determine the effect of DNA methylation on the epigenetic landscape and the function in higher organisms due to the lack of DNA methylation-free mutants. [RESULTS] Here, the analysis of a recently generated Arabidopsis mutant completely devoid of DNA methylation reveals that DNA methyl...
Chromatin state; DNA methylation-free plant; Histone modification
null
null
null
null
null
36,126,941
Reliability of Y Balance Test in Runners With Intellectual Disability.
Journal of sport rehabilitation
J Sport Rehabil
32
1
10.1123/jsr.2022-0030
eng
2,023
1
1
2,022
9
20
[CONTEXT] The Y Balance Test (YBT) is a simple, reliable, cost-effective screening test. It is used to evaluate dynamic balance as well as to determine the potential risk of injury of the lower limbs. The reliability of YBT has been widely reported in the general population. However, there are no studies evaluating the...
dynamic balance; intraclass correlation; short-distance running
0.58
66
Biophysics; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine
2,023
36,126,905
A case series of perioperative anaphylaxis to cefazolin during kidney transplant and review of literature.
Transplant immunology
Transpl Immunol
75
null
10.1016/j.trim.2022.101720
eng
2,022
12
null
2,022
9
17
[BACKGROUND] Intraoperative anaphylaxis is a life threatening and multiorgan system hypersensitivity reaction that frequently leads to cessation of operations. Despite the incidence of Cefazolin allergy being on the rise, the cases of anaphylaxis to Cefazolin during surgeries and its management are seldom reported. [CA...
Anaphylaxis; Cefazolin; Kidney transplant
0.355
68
Immunology and Allergy; Transplantation; Immunology
Immunology and Microbiology; Medicine
2,022
36,126,423
Association of fetal heart rate short term variability pattern during term labor with neonatal morbidity and small for gestational age status.
European journal of obstetrics, gynecology, and reproductive biology
Eur J Obstet Gynecol Reprod Biol
278
null
10.1016/j.ejogrb.2022.08.026
eng
2,022
11
null
2,022
9
5
[OBJECTIVE] To assess the association of fetal heart rate short-term variability (STV) pattern during term labor with both neonatal composite morbidity (cord blood pH ≤ 7.10 and/or neonatal intensive care unit admission and/or Apgar score at 5 min 7) and small for gestational age (SGA) status. [STUDY DESIGN] Retrospect...
FHR; Fetal acidosis; Neonatal outcomes; SGA; STV; Short term variability; Small for gestational age; cCTG
null
null
null
null
null
36,126,407
Identification of Pinelliae Rhizoma and its counterfeit species based on enzymatic signature peptides from toxic proteins.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Phytomedicine
107
null
10.1016/j.phymed.2022.154451
eng
2,022
12
null
2,022
9
11
[BACKGROUND] Pinelliae Rhizoma (PR), a toxic medication, with long history, is commonly used for eliminating phlegm. Due to the shortage of wild resources and the relative lacking of cultivation technology, it is often confused with its counterfeit species in the market, such as Typhonii Rhizoma (TR), Arisaematis Rhizo...
Pinelliae Rhizoma; Proteogenomics; Signature peptides; Species authentication; Toxicity
1.126
150
Complementary and Alternative Medicine; Drug Discovery; Pharmaceutical Science; Pharmacology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,126,087
Socioeconomic inequalities in the risk factors of noncommunicable diseases (hypertension and diabetes) among Bangladeshi population: Evidence based on population level data analysis.
PloS one
PLoS One
17
9
10.1371/journal.pone.0274978
eng
2,022
null
null
2,022
9
20
[BACKGROUND] Noncommunicable diseases (NCDs) such as hypertension and diabetes are among the most fatal disease and prevalent among the adult population worldwide, including Bangladesh, and pose a public health threat. Understanding the socioeconomic inequalities linked to NCD risk factors can aid in the development of...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,125,563
Effects of acute intravenous lipopolysaccharide administration on the plasma lipidome and metabolome in lactating Holstein cows experiencing hyperlipidemia.
Metabolomics : Official journal of the Metabolomic Society
Metabolomics
18
10
10.1007/s11306-022-01928-1
eng
2,022
9
19
2,022
9
19
[INTRODUCTION] The effects of lipopolysaccharides (i.e., endotoxin; LPS) on metabolism are poorly defined in lactating dairy cattle experiencing hyperlipidemia. [OBJECTIVES] Our objective was to explore the effects of acute intravenous LPS administration on metabolism in late-lactation Holstein cows experiencing hyperl...
Dairy cow; Lipidome; Lipopolysaccharide; Metabolome
0.762
103
Biochemistry; Clinical Biochemistry; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,125,425
Frequency and Pattern of Rheumatoid Arthritis in a Tertiary Hospital in Maiduguri, North-Eastern Nigeria.
West African journal of medicine
West Afr J Med
39
9
null
eng
2,022
9
16
null
null
null
[BACKGROUND] Rheumatoid arthritis (RA) is considered rare and mild in Africa, its exact burden is unknown. [OBJECTIVES] To determine the pattern of RA and medications used in its management at University of Maiduguri Teaching Hospital (UMTH), Nigeria. [METHODS] A retrospective cross-sectional study of RA patients, aged...
Disease activity management; Investigations; Northeastern Nigeria; Rheumatoid arthritis
null
null
null
null
null
36,124,902
Efficacy of surgical skin preparation with chlorhexidine in alcohol according to the concentration required to prevent surgical site infection: meta-analysis.
BJS open
BJS Open
6
5
10.1093/bjsopen/zrac111
eng
2,022
9
2
null
null
null
[BACKGROUND] A combination of chlorhexidine gluconate and alcohol (CHG-alcohol) is recommended for surgical skin preparation to prevent surgical site infection (SSI). Although more than 1 per cent CHG-alcohol is recommended to prevent catheter-related bloodstream infections, there is no consensus regarding the concentr...
null
1.149
39
Medicine; Surgery
Medicine
2,022
36,124,853
Alternative quinolone-resistance pathway caused by simultaneous horizontal gene transfer in Haemophilus influenzae.
The Journal of antimicrobial chemotherapy
J Antimicrob Chemother
77
12
10.1093/jac/dkac312
eng
2,022
11
28
null
null
null
[BACKGROUND] Quinolone-resistant bacteria are known to emerge via the accumulation of mutations in a stepwise manner. Recent studies reported the emergence of quinolone low-susceptible Haemophilus influenzae ST422 isolates harbouring two relevant mutations, although ST422 isolates harbouring one mutation were never ide...
null
1.382
229
Infectious Diseases; Microbiology; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,124,739
Benefit of Risk-stratified Prophylactic Treatment on Clinical Outcome in Postoperative Crohn's Disease.
Journal of Crohn's colitis
J Crohns Colitis
17
3
10.1093/ecco-jcc/jjac139
eng
2,023
4
3
null
null
null
[BACKGROUND AND AIMS] Whereas immediate postoperative treatment has shown effectiveness in reducing endoscopic postoperative recurrence [POR], evidence regarding the clinical benefit is limited. We compared rates of clinical POR in Crohn's disease [CD] patients receiving immediate prophylactic treatment with rates in p...
Inflammatory bowel disease; postoperative recurrence; prevention; risk stratification
null
null
null
null
null
36,124,692
Self-reported health and adverse outcomes among women living with symptoms of angina or unspecific chest pain but no diagnosis of obstructive coronary artery disease-findings from the DenHeart study.
European journal of cardiovascular nursing
Eur J Cardiovasc Nurs
22
5
10.1093/eurjcn/zvac085
eng
2,023
7
19
null
null
null
[AIMS] The objectives were to describe differences in self-reported health at discharge between women diagnosed with angina or unspecific chest pain and investigate the association between self-reported health and adverse outcomes within 3 years. [METHODS AND RESULTS] Data from a national cohort study were used, includ...
Angina pectoris; Chest pain; Patient-reported outcomes; Revascularization
0.898
66
Advanced and Specialized Nursing; Medical and Surgical Nursing; Medicine; Cardiology and Cardiovascular Medicine
Medicine; Nursing
2,023
36,124,645
Nutritionally adequate and environmentally respectful diets are possible for different diet groups: an optimized study from the NutriNet-Santé cohort.
The American journal of clinical nutrition
Am J Clin Nutr
116
6
10.1093/ajcn/nqac253
eng
2,022
12
19
null
null
null
[BACKGROUND] Research has shown that vegetarian diets have a low environmental impact, but few studies have examined the environmental impacts and nutritional adequacy of these diets together, even though vegetarian diets can lead to nutritional issues. [OBJECTIVES] Our objective was to optimize and compare 6 types of ...
diet optimization; healthy diets; meat consumers; nutritional references; plant-based diets; sustainable diets; vegetarians
1.96
390
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,022
36,124,219
A novel chest CT severity score in COVID-19 and its correlation with severity and prognosis of the lung disease: A retrospective cohort study.
Annals of medicine and surgery (2012)
Ann Med Surg (Lond)
82
null
10.1016/j.amsu.2022.104692
eng
2,022
10
null
2,022
9
15
[BACKGROUND] HRCT chest has a high sensitivity in the diagnosis of patients with COVID-19 infection. Through our study, we intend to evaluate the diagnostic accuracy and inter-reader variability of a semi-quantitative CT severity score, a novel parameter designed for risk stratification and prognostication of COVID-19 ...
Coronavirus; Cough; Covid-19; Pneumonia; hrct
null
null
null
null
null
36,123,842
Efficacy of decitabine combined with allogeneic hematopoietic stem cell transplantation in the treatment of recurrent and refractory acute myeloid leukemia (AML): A systematic review and meta-analysis.
Medicine
Medicine (Baltimore)
101
37
10.1097/MD.0000000000030644
eng
2,022
9
16
null
null
null
[BACKGROUND] This analysis aimed to assess the effect of decitabine combined with allogeneic hematopoietic stem cell transplantation (allo-HSCT) in treating recurrent and refractory acute myeloid leukemia. [METHOD] The present analysis was carried out according to the principles of Preferred Reporting Items for Systema...
null
null
null
null
null
null
36,123,715
Case report: genetic analysis of a child with 18q deletion syndrome and developmental dysplasia of the hip.
BMC medical genomics
BMC Med Genomics
15
1
10.1186/s12920-022-01345-2
eng
2,022
9
19
2,022
9
19
[OBJECTIVE] To analyze the genotypes and phenotypes of a child with developmental dysplasia of the hip (DDH), developmental delays, recurrent fever, hypothyroidism and cleft palate. [METHODS] G-banding karyotyping analysis and next-generation sequencing (NGS) were performed for the patient. The genotypes of the parents...
18q deletion syndrome; Developmental dysplasia of the hip; HSPG2; fever; Next-generation sequencing
0.892
99
Genetics; Genetics
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,123,711
The immune microenvironment of HPV-positive and HPV-negative oropharyngeal squamous cell carcinoma: a multiparametric quantitative and spatial analysis unveils a rationale to target treatment-naïve tumors with immune checkpoint inhibitors.
Journal of experimental clinical cancer research : CR
J Exp Clin Cancer Res
41
1
10.1186/s13046-022-02481-4
eng
2,022
9
20
2,022
9
20
[BACKGROUND] Immune checkpoint inhibitors (ICI) are approved for treatment of recurrent or metastatic oropharyngeal head and neck squamous cell carcinoma in the first- and second-line settings. However, only 15-20% of patients benefit from this treatment, a feature increasingly ascribed to the peculiar characteristics ...
Gene expression profile; Head and neck squamous cell carcinoma; Human papillomavirus; Immunotherapy; Multiplex immunofluorescence; Oropharyngeal carcinoma; Sex; Tumor microenvironment
null
null
null
null
null
36,123,543
Transanally assisted lateral pelvic lymph node dissection for rectal cancer.
Surgical endoscopy
Surg Endosc
37
2
10.1007/s00464-022-09617-9
eng
2,023
2
null
2,022
9
19
[BACKGROUND] Although lateral pelvic lymph node dissection (LLND) might be an effective approach for patients with rectal cancer with lateral lymph node metastasis, it is technically challenging because of the anatomical complexity and location of the deep pelvis. An assistance by transanal approach might be useful for...
LLND; Rectal cancer; Transanal
1.12
178
Surgery
Medicine
2,023
36,123,415
Regional Patterns of Hospital-Level Guideline Adherence in Gastric Cancer: An Analysis of the National Cancer Database.
Annals of surgical oncology
Ann Surg Oncol
30
1
10.1245/s10434-022-12549-2
eng
2,023
1
null
2,022
9
19
[BACKGROUND] Adherence to evidence-based guidelines for gastric cancer is low, particularly at the hospital level, despite a strong association with improved overall survival (OS). We aimed to evaluate patterns of hospital and regional adherence to National Comprehensive Cancer Network guidelines for gastric cancer. [M...
null
1.037
210
Surgery; Oncology
Medicine
2,023
36,123,255
Patient Safety Initiatives in Cosmetic Breast Surgery: A Systematic Review.
Journal of plastic, reconstructive aesthetic surgery : JPRAS
J Plast Reconstr Aesthet Surg
75
11
10.1016/j.bjps.2022.06.099
eng
2,022
11
null
2,022
6
28
[BACKGROUND] Improved patient safety (PS) in cosmetic breast surgery relies upon high-quality evidence. The objective of this study was to systematically review the existing evidence for PS and quality improvement (QI) in cosmetic breast surgery. [METHODS] A systematic review of published plastic surgery literature fro...
Anaplastic large cell lymphoma; Antisepsis; Breast implants; Cosmetic breast surgery; Infection; Patient safety; Quality improvement; Seroma
null
null
null
null
null
36,121,843
Digestive tolerability and acceptability of Fibersol-2 in healthy and diarrheal children 1-3 years old at a rural facility, Bangladesh: Results from a four arm exploratory study.
PloS one
PLoS One
17
9
10.1371/journal.pone.0274302
eng
2,022
null
null
2,022
9
19
[BACKGROUND] Fibersol-2 has some beneficial effects on human health. We aimed to evaluate the digestive tolerability and acceptability of Fibersol-2 in healthy and diarrheal children, as well as improvement in stool consistencies in young diarrheal children. [METHODS] Sixty children of either sex, aged 1-3 years having...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,121,669
Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease: Two Phase 3 Randomized Placebo-Controlled Trials.
JAMA neurology
JAMA Neurol
79
11
10.1001/jamaneurol.2022.2909
eng
2,022
11
1
null
null
null
[IMPORTANCE] Alzheimer disease (AD), a neurodegenerative disease characterized by β-amyloid plaques and τ tangles in the brain, represents an unmet medical need with no fully approved therapeutics to modify disease progression. [OBJECTIVE] To investigate the safety and efficacy of crenezumab, a humanized monoclonal imm...
null
null
null
null
null
null
36,121,141
Reciprocal effects of mathematics performance, school engagement and burnout during adolescence.
The British journal of educational psychology
Br J Educ Psychol
93
1
10.1111/bjep.12548
eng
2,023
3
null
2,022
9
19
[BACKGROUND] Transitioning into adolescence while simultaneously facing greater academic demands as the level of education increases often entails both academic challenges and general declines in students' school-related well-being. Still, however, relatively little is known about the causal relationship between studen...
cross-lagged panel model; longitudinal relations; mathematics performance; school burnout; school engagement
1.738
120
Developmental and Educational Psychology; Education
Psychology; Social Sciences
2,023
36,120,736
Clinical analysis of high-intensity focused ultrasound (HIFU) combined with hysteroscopy-guided suction curettage (HGSC) in patients with cervical pregnancy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
Int J Hyperthermia
39
1
10.1080/02656736.2022.2123565
eng
2,022
null
null
null
null
null
[OBJECTIVE] To evaluate the effectiveness of high-intensity focused ultrasound (HIFU) combined with hysteroscopy-guided suction curettage (HGSC) in treating cervical pregnancy. [MATERIALS AND METHODS] This is a retrospective study. Seven patients with cervical pregnancy who visited the Third Xiangya Hospital of Central...
Ultrasound-guided HIFU ablation; cervical pregnancy; hysteroscopy-guided suction curettage
0.762
103
Medicine; Physiology; Physiology; Radiological and Ultrasound Technology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine
2,022
36,120,401
Detection of ADHD From EOG Signals Using Approximate Entropy and Petrosain's Fractal Dimension.
Journal of medical signals and sensors
J Med Signals Sens
12
3
10.4103/jmss.jmss_119_21
eng
2,022
null
null
2,022
7
26
[BACKGROUND] Previous research has shown that eye movements are different in patients with attention deficit hyperactivity disorder (ADHD) and healthy people. As a result, electrooculogram (EOG) signals may also differ between the two groups. Therefore, the aim of this study was to investigate the recorded EOG signals ...
Approximate entropy; Petrosian's fractal dimension; attention deficit hyperactivity disorder; electrooculogram; neural gas; support vector machine
null
null
null
null
null
36,120,282
Assessment of Parental Perceptions of Socio-Psychological Factors, Unmet Dental Needs, and Barriers to Utilise Oral Health Care in Autistic Children.
Cureus
Cureus
14
8
10.7759/cureus.27950
eng
2,022
8
null
2,022
8
12
[INTRODUCTION] Parents' participation is crucial in the dental health intervention of children with autism spectrum disorder (ASD). Parenting children with ASD is extremely stressful and challenging. Parents and other caregivers have a responsibility to care for and raise children with ASD. Parental perception of the c...
austism; dental caries; health care service; oral hygeine status; parents; perception; questionnaire; unmet need; validity
null
null
null
null
null
36,119,961
It's Not You, It's SOSA: A Case Study on Breaking Up With an FDA-Cleared Susceptibility Testing System's Oxacillin Results for Staphylococcus spp. Other Than S. aureus and S. lugdunensis.
Open forum infectious diseases
Open Forum Infect Dis
9
9
10.1093/ofid/ofac421
eng
2,022
9
null
2,022
8
17
[BACKGROUND] In 2021, the Clinical and Laboratory Standards Institute revised its susceptible oxacillin minimum inhibitory concentration (MIC) breakpoint for Staphylococcus spp. other than S. aureus and S. lugdunensis (SOSA) from ≤0.25 to ≤0.5 µg/mL. Here, we describe the response to this breakpoint change, which at th...
VITEK 2; antimicrobial susceptibility testing; breakpoint; coagulase-negative Staphylococcus spp; oxacillin
1.498
74
Infectious Diseases; Oncology
Medicine
2,022
36,119,744
Inflammatory bowel disease and cardiovascular disease: A two-sample Mendelian randomization analysis.
Frontiers in cardiovascular medicine
Front Cardiovasc Med
9
null
10.3389/fcvm.2022.927120
eng
2,022
null
null
2,022
9
2
[BACKGROUND] Although epidemiological studies have shown a positive relationship between inflammatory bowel disease (IBD) and risk of cardiovascular disease (CVD) outcomes, a solid causal relationship has not been established. Thus, a two-sample Mendelian randomization (MR) study was conducted to explore the potential ...
Mendelian randomization; cardiovascular diseases; causation; genome-wide association study; inflammatory bowel disease
1.391
81
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,119,705
The ratio of serum neuron-specific enolase level to admission glasgow coma scale score is associated with diffuse axonal injury in patients with moderate to severe traumatic brain injury.
Frontiers in neurology
Front Neurol
13
null
10.3389/fneur.2022.887818
eng
2,022
null
null
2,022
9
1
[BACKGROUND] Moderate to severe traumatic brain injury (TBI) is frequently accompanied by diffuse axonal injury (DAI). Considering the low sensitivity of computed tomography (CT) examination for microbleeds and axonal damage, identification of DAI is difficult using conventional diagnostic methods in the acute phase. N...
biomarker; diffuse axonal injury; early diagnosis; neuron specific enolase; traumatic brain injury
0.978
118
Neurology; Neurology
Medicine; Neuroscience
2,022
36,119,352
Clinical profile of hemophilia B patients from Karnataka.
Journal of family medicine and primary care
J Family Med Prim Care
11
6
10.4103/jfmpc.jfmpc_1773_21
eng
2,022
6
null
2,022
6
30
[BACKGROUND] The most prevalent severe inherited hemorrhagic condition is hemophilia, which means "love of blood." Hemophilia A and B are caused by a lack or malfunction of the factor VIII and factor IX proteins. [OBJECTIVE] The present study is to determine the prevalence and clinical profile of hereditary coagulation...
Epidemiology; F9 gene; Karnataka; hemophilia B
null
null
null
null
null
36,119,173
Clinical profile and spectrum of bacteriuria in patients with diabetes: An analytical study.
Journal of family medicine and primary care
J Family Med Prim Care
11
6
10.4103/jfmpc.jfmpc_1779_21
eng
2,022
6
null
2,022
6
30
[INTRODUCTION] Diabetes is one of the modern-day epidemics with a spectrum of complications. Urinary tract infections (UTI) are common among patients with diabetes, and often it goes unnoticed in the initial period, which can later lead to complications. This study was planned to find out the magnitude of the problem o...
Bacteriuria; UTI; diabetes
null
null
null
null
null
36,119,134
Effects of FTY720 on Neural Cell Behavior in Two and Three-Dimensional Culture and in Compression Spinal Cord Injury.
Cellular and molecular bioengineering
Cell Mol Bioeng
15
4
10.1007/s12195-022-00724-0
eng
2,022
8
null
2,022
4
8
[INTRODUCTION] The present study aimed to evaluate the effects of FTY720 as a neuromodulatory drug on the behaviors of neural stem/progenitor cells (NS/PCs) in two-dimensional (2-D) and three-dimensional (3-D) cultures and in spinal cord injury (SCI). [METHODS] The NS/PCs isolated from the ganglionic eminence of the 13...
FTY720; Migration; Neural stem cells; Proliferation; Spinal cord injury; Survival
0.734
48
Biochemistry, Genetics and Molecular Biology; Modeling and Simulation
Biochemistry, Genetics and Molecular Biology; Mathematics
2,022