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36,118,728
Bilateral asymptomatic common carotid artery stenosis: Mouse model for stroke research.
Open veterinary journal
Open Vet J
12
4
10.5455/OVJ.2022.v12.i4.7
eng
2,022
null
null
2,022
7
13
[BACKGROUND] Asymptomatic carotid artery stenosis has become more prevalent worldwide and is often associated with a poor prognosis. Numerous guidelines highlighted surgical interventions as treatment for carotid artery stenosis, but only a few recommendations were made regarding non-surgical interventions due to its l...
Animal models of disease; Carotid arteries; Mouse models; Non-communicable disease; Scientific research
0.34
22
Veterinary
Veterinary
2,022
36,117,920
Decreased cognitive function is associated with preceding severe hypoglycemia and impaired blood glucose control in the elderly individuals with type 1 diabetes.
Diabetology international
Diabetol Int
13
4
10.1007/s13340-022-00588-9
eng
2,022
10
null
2,022
5
25
[AIM/INTRODUCTION] This investigation aimed to clarify the relationship between cognitive function and blood glucose control in the elderly individuals with type 1 diabetes. [MATERIALS AND METHODS] In total, 45 patients with type 1 diabetes, age 74.9 ± 6.7 years, and HbA1c levels of 7.9 ± 0.9% were studied. Severe hypo...
Cognitive dysfunction; Elderly individuals; Hypoglycemia; Type 1 diabetes
0.642
28
Internal Medicine; Endocrinology, Diabetes and Metabolism
Medicine
2,022
36,117,894
Prevalence of Facial Asymmetry and Correction Methods for Rhinoplasty in Individuals with Deviated Nose: A Brief Review.
World journal of plastic surgery
World J Plast Surg
11
2
10.52547/wjps.11.2.18
eng
2,022
7
null
null
null
null
[BACKGROUND] Surgeons frequently perform rhinoplasty on individuals who have facial asymmetry. Patients' discontent following rhinoplasty has been linked to facial asymmetry. On the other hand, correction of a deviated nose is a tough procedure, and it is not the same as septal deviation correction. Surgeons, who often...
Asymmetrical face; Deviated nose; Facial asymmetry; Rhinoplasty
null
null
null
null
null
36,117,826
Treatment of Periprosthetic Joint Infection and Fracture-Related Infection With a Temporary Arthrodesis Made by PMMA-Coated Intramedullary Nails - Evaluation of Technique and Quality of Life in Implant-Free Interval.
Frontiers in surgery
Front Surg
9
null
10.3389/fsurg.2022.917696
eng
2,022
null
null
2,022
9
2
[BACKGROUND] Antimicrobial coating of intramedullary nails with polymethyl methacrylate (PMMA) bone cement promises infection control and stabilization for subsequent bone healing. However, when removing the implant, bone cement can debond and remain in the medullary cavity of the long bones, representing a nidus for r...
coated implants; fracture-related infection; periprosthetic joint infection; polymethyl methacrylate (PMMA); psychological outcomes; quality of life; temporary arthrodesis
0.459
48
Surgery
Medicine
2,022
36,117,627
Longitudinal monitoring of amyotrophic lateral sclerosis by diffusion tensor imaging: Power calculations for group studies.
Frontiers in neuroscience
Front Neurosci
16
null
10.3389/fnins.2022.929151
eng
2,022
null
null
2,022
8
10
[INTRODUCTION] Diffusion tensor imaging (DTI) can be used to map disease progression in amyotrophic lateral sclerosis (ALS) and therefore is a promising candidate for a biomarker in ALS. To this end, longitudinal study protocols need to be optimized and validated regarding group sizes and time intervals between visits....
Amyotrophic Lateral Sclerosis; Diffusion Tensor Imaging; longitudinal design; statistical power; study optimization
1.161
170
Neuroscience
Neuroscience
2,022
36,117,550
FOXO1 Is Present in Stomach Epithelium and Determines Gastric Cell Distribution.
Gastro hep advances
Gastro Hep Adv
1
5
10.1016/j.gastha.2022.05.005
eng
2,022
null
null
2,022
5
14
[BACKGROUND AND AIMS] Stomach cells can be converted to insulin-producing cells by Neurog3, MafA, and Pdxl over-expression. Enteroendocrine cells can be similarly made to produce insulin by the deletion of FOXO1. Characteristics and functional properties of FOXO1-expressing stomach cells are not known. [METHODS] Using ...
Cell Cycle; Diabetes Treatment; Enteroendocrine Cells; Parietal Cells; Transcription Factor
null
9
Gastroenterology; Hepatology; Medicine
Medicine
2,022
36,117,522
Integration of artificial intelligence into nursing practice.
Health and technology
Health Technol (Berl)
12
6
10.1007/s12553-022-00697-0
eng
2,022
null
null
2,022
9
14
[BACKGROUND] Artificial Intelligence (AI) is developing at a rapid pace and finding new applications across the health service team. Some professionals have voiced concerns over the implementation of AI, whilst others predict greater job opportunities in the future. Nursing practice will be directly affected and furthe...
Acceptance; Artificial intelligence; Future applications of AI; Integrate into practice; Nurse; Technology in nursing
null
null
null
null
null
36,117,495
Decellularized human amniotic membrane engraftment in combination with adipose-derived stem cells transplantation, synergistically improved diabetic wound healing.
Journal of cosmetic dermatology
J Cosmet Dermatol
21
12
10.1111/jocd.15394
eng
2,022
12
null
2,022
9
25
[BACKGROUND] One of the most important and common complications of diabetes is a disorder and defect in diabetic wound healing. [AIMS] The aim of present study was to investigate the synergistic effects of decellularized human amniotic membrane (dHAM) engraftment and adipose-derived stem cells (ADSs) transplantation in...
adipose-derived Stem Cells; diabetic Wound; human amniotic membrane
0.61
67
Dermatology
Medicine
2,022
36,117,227
Primary spindle cell tumor originating from the liver that was difficult to diagnose.
Surgical case reports
Surg Case Rep
8
1
10.1186/s40792-022-01530-6
eng
2,022
9
19
2,022
9
19
[BACKGROUND] It has been reported that hepatocellular carcinoma (HCC) with spindle cell tumor accounts for 1.8% of all HCCs, but spindle cell tumors that do not show an obvious conventional HCC are extremely rare. In this report, we describe a case of resection of a primary spindle cell tumor of the liver that was diff...
Hepatectomy; Immunostaining; Liver; Pathology; Spindle cell tumor
null
null
null
null
null
36,117,175
Misdiagnosis of carcinoma gall bladder in endemic regions.
BMC surgery
BMC Surg
22
1
10.1186/s12893-022-01793-8
eng
2,022
9
18
2,022
9
18
[BACKGROUND] Incidental carcinoma gall bladder and benign disease in radical cholecystectomy specimen is the cause of concern. We attempted to find out the incidence and reasons thereof in the present study. [METHODS] Present study is a retrospective analysis of a prospectively maintained database between July 2002 and...
Carcinoma gallbladder; Endemic region; Over-diagnosis; Radical cholecystectomy; Under-diagnosis
0.502
64
Surgery; Medicine
Medicine
2,022
36,117,092
Mortality According to Treatment in Metastatic Collecting Duct Renal Cell Carcinoma.
Clinical genitourinary cancer
Clin Genitourin Cancer
21
2
10.1016/j.clgc.2022.08.010
eng
2,023
4
null
2,022
8
26
[INTRODUCTION] Controlled contemporary analyses of mortality in metastatic collecting duct renal cell carcinoma (mcdRCC) are unavailable. We addressed this knowledge gap and tested rates of treatment and associated mortality in patients with mcdRCC. [PATIENTS AND METHODS] Within Surveillance, Epidemiology, and End Resu...
Collecting duct carcinoma; Overall mortality; RCC; SEER; Variant histology
1.056
59
Urology; Oncology
Medicine
2,023
36,116,976
Multidimensional machine learning models predicting outcomes after trauma.
Surgery
Surgery
172
6
10.1016/j.surg.2022.08.007
eng
2,022
12
null
2,022
9
16
[BACKGROUND] An emerging body of literature supports the role of individualized prognostic tools to guide the management of patients after trauma. The aim of this study was to develop advanced modeling tools from multidimensional data sources, including immunological analytes and clinical and administrative data, to pr...
null
null
null
null
null
null
36,116,867
The efficacy of religious and spiritual interventions in nursing care to promote mental, physical and spiritual health: A systematic review and meta-analysis.
Applied nursing research : ANR
Appl Nurs Res
67
null
10.1016/j.apnr.2022.151618
eng
2,022
10
null
2,022
7
16
[BACKGROUND] Spiritual interventions have proved to alleviate suffering, help the patient to prepare for end of life issues, improve quality of life, and well-being. [OBJECTIVE] This study aims to investigate the efficacy of religious and spiritual interventions in nursing care to promote mental, physical and spiritual...
Coping behaviors; Meta-analyses; Nursing care; Randomized control trials; Spiritual care
0.577
69
Nursing
Nursing
2,022
36,116,714
Serum Selenium Levels in Patients With Graves Disease With or Without Thyroid Ophthalmopathy.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Endocr Pract
28
12
10.1016/j.eprac.2022.09.001
eng
2,022
12
null
2,022
9
16
[BACKGROUND] Graves disease is one of the most common autoimmune thyroid diseases. Thyroid has the highest concentration of selenium (Se) in the body. Se plays a crucial role in the functioning of some thyroid enzymes; however, there are controversial results regarding the administration of serum Se levels in patients ...
Graves disease; Graves orbitopathy; selenium; serum; thyroid ophthalmopathy
1.003
107
Medicine; Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,116,711
Radiomics analysis of short tau inversion recovery images in cardiac magnetic resonance for the prediction of late gadolinium enhancement in patients with acute myocarditis.
Magnetic resonance imaging
Magn Reson Imaging
94
null
10.1016/j.mri.2022.09.004
eng
2,022
12
null
2,022
9
16
[RATIONALE AND OBJECTIVES] Cardiac Magnetic Resonance (CMR) imaging is recommended as the reference diagnostic non-invasive modality for myocarditis but is often limited by patients' compliance. The purpose of this study is to evaluate the validity of Radiomics applied to Short Tau Inversion Recovery (STIR) sequences, ...
Myocarditis, cardiac magnetic resonance; Radiomics
0.733
126
Biomedical Engineering; Biophysics; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Engineering; Medicine
2,022
36,116,548
A systematic review of the correlation between Trichomonas vaginalis infection and infertility.
Acta tropica
Acta Trop
236
null
10.1016/j.actatropica.2022.106693
eng
2,022
12
null
2,022
9
15
[BACKGROUND] Trichomonas vaginalis (T. vaginalis) is an extracellular flagellated protozoan parasitizing the human genital and urinary tracts. T. vaginalis infection impacts human reproductive function, but whether it causes infertility is still a matter of debate. [METHODS] In this work, we consulted 205 relevant arti...
Correlation; Infection; Infertility; Systematic review; Trichomonas vaginalis
0.751
122
Insect Science; Veterinary; Infectious Diseases; Parasitology
Agricultural and Biological Sciences; Immunology and Microbiology; Medicine; Veterinary
2,022
36,116,032
Adherence with cardiovascular medications and the outcomes in patients with coronary arterial disease: "Real-world" evidence.
Clinical cardiology
Clin Cardiol
45
12
10.1002/clc.23898
eng
2,022
12
null
2,022
9
18
[BACKGROUND] Cardiovascular medications are vital for the secondary prevention of coronary arterial disease (CAD). However, the effect of cardiovascular medication may depend on the optimal adherence of the patients. This meta-analysis aims to determine the magnitude of adherence to vascular medications that influences...
ACEI/ARB; beta-blocker; coronary heart disease; dose-response; medication adherence; risk factor; statin
0.806
89
Cardiology and Cardiovascular Medicine; Medicine
Medicine
2,022
36,115,990
The vaginal and uterine blood flow changes during the ovsynch program and its impact on the pregnancy rates in Holstein dairy cows.
BMC veterinary research
BMC Vet Res
18
1
10.1186/s12917-022-03444-9
eng
2,022
9
17
2,022
9
17
[AIM] OvSynch is a hormonal protocol for synchronization of estrus and use of artificial insemination (AI) at an optimal time without adverse effects on the ovaries or uterus. This study investigated the use of noninvasive color Doppler ultrasound to assess changes in uterine and vaginal blood flow during the Ovsynch p...
Ovsynch; Uterine blood flow; Vaginal blood flow
0.668
86
Veterinary; Medicine
Medicine; Veterinary
2,022
36,115,948
Neutralization of the Staphylococcus aureus Panton-Valentine leukocidin by African and Caucasian sera.
BMC microbiology
BMC Microbiol
22
1
10.1186/s12866-022-02636-5
eng
2,022
9
17
2,022
9
17
[BACKGROUND] The prevalence of Staphylococcus aureus isolates carrying the Panton-Valentine leukocidin (PVL) gene is higher in Africa (≈50%) compared to Europe ( 5%). The study aimed to measure anti-PVL-antibodies in Africans and Germans in a multi-center study and to test whether detected antibodies can neutralize the...
Neutralization test; Panton-Valentine leukocidin; Polymorphonuclear leukocytes; Staphylococcus aureus
0.937
147
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,022
36,115,819
Hypothermia as an Adjunctive Therapy to Percutaneous Intervention in ST-Elevation Myocardial Infarction: A Systematic Review and Meta-Analysis of Randomized Control Trials.
Cardiovascular revascularization medicine : including molecular interventions
Cardiovasc Revasc Med
47
null
10.1016/j.carrev.2022.09.005
eng
2,023
2
null
2,022
9
12
[INTRODUCTION] In the setting of acute ST-elevation myocardial infarction (STEMI), several randomized control trials (RCTs) suggested a potential benefit with the use of therapeutic hypothermia (TH). However, results from previous studies are contradictory. [METHOD] We performed a comprehensive literature search for st...
Acute coronary syndrome; Cooling; Hypothermia; Infarction size; Left ventricle ejection fraction; Percutaneous coronary intervention; STEMI
0.493
47
Cardiology and Cardiovascular Medicine; Medicine
Medicine
2,023
36,115,814
Ischemia With Nonobstructive Coronary Arteries: Insights From the ISCHEMIA Trial.
JACC. Cardiovascular imaging
JACC Cardiovasc Imaging
16
1
10.1016/j.jcmg.2022.06.015
eng
2,023
1
null
2,022
9
14
[BACKGROUND] Ischemia with nonobstructive coronary arteries (INOCA) is common clinically, particularly among women, but its prevalence among patients with at least moderate ischemia and the relationship between ischemia severity and non-obstructive atherosclerosis severity are unknown. [OBJECTIVES] The authors investig...
coronary CT angiography; ischemia; ischemia with nonobstructive coronary arteries; stress testing
null
null
null
null
null
36,115,766
Investigation of the potential of leukoreduction filters in the creation of anti-inflammatory compound.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
Transfus Apher Sci
62
1
10.1016/j.transci.2022.103520
eng
2,023
2
null
2,022
8
24
[BACKGROUND] Some viruses such as SARS, SARS-CoV-2, and MERS cause an imbalance in immune responses and leads to an acute inflammatory reaction named cytokine storm. In this situation, an anti-inflammatory component can modulate the immune system and decrease mortality. The aim of this study was investigate the potenti...
Betamethasone; IL1; IL1Ra; Leukoreduction filters; SARA-CoV-2
0.423
66
Hematology
Medicine
2,023
36,117,760
Berberine exerts antidepressant-like effects via regulating miR-34a-synaptotagmin1/Bcl-2 axis.
Chinese herbal medicines
Chin Herb Med
13
1
10.1016/j.chmed.2020.11.001
eng
2,021
1
null
2,020
12
1
[OBJECTIVE] Berberine, a cationic alkaloid first isolated in 1917, has been approved by the China Drug Administration for decades. Accumulating evidence demonstrated its antidepressant-like activities in vivo. Our previous study has shown that chronic stress leads to the upregulation of miR-34a in the hippocampus of mi...
Bcl-2; berberine; miR-34a; mitochondria; spinal morphology; synaptotagmin-1
0.199
25
Complementary and Alternative Medicine; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,021
36,119,017
bHLH transcription factor SmbHLH92 negatively regulates biosynthesis of phenolic acids and tanshinones in Salvia miltiorrhiza.
Chinese herbal medicines
Chin Herb Med
12
3
10.1016/j.chmed.2020.04.001
eng
2,020
7
null
2,020
4
19
[OBJECTIVE] Salvia miltiorrhiza is a valuable herbal medicine with tanshinone and phenolic acid as the main biological active ingredients. The biosynthetic regulation of these bioactive compounds is controlled by a set of transcription factors (TFs). The basic helix-loop-helix (bHLH) transcription factor plays an impor...
Salvia miltiorrhiza bunge; SmbHLH92; phenolic acid; tanshinone; transcription factor
null
25
Complementary and Alternative Medicine; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,020
36,176,033
Understanding the Technological Landscape of Home Health Aides: Scoping Literature Review and a Landscape Analysis of Existing mHealth Apps.
Journal of medical Internet research
J Med Internet Res
24
11
10.2196/39997
eng
2,022
11
11
2,022
11
11
[BACKGROUND] Home health aides (HHAs) provide necessary hands-on care to older adults and those with chronic conditions in their homes. Despite their integral role, HHAs experience numerous challenges in their work, including their ability to communicate with other health care professionals about patient care while car...
educational technology; home care services; home health aides; mHealth; mobile apps; mobile health; mobile phone; mobile phone apps; smartphones; technology
1.992
214
Health Informatics
Medicine
2,022
36,175,987
Assessment of awareness and knowledge of schistosomiasis among school-aged children (6-13 years) in the Okavango Delta, Botswana.
Global health research and policy
Glob Health Res Policy
7
1
10.1186/s41256-022-00267-x
eng
2,022
9
30
2,022
9
30
[BACKGROUND] Schistosomiasis is a global health problem affecting 250 million people, with 90% in Sub-Saharan Africa. In Botswana, the burden is high in the Okavango delta because of the water channels. WHO recommends integrated measures, including access to clean water, sanitation, health education, and drugs to contr...
Awareness; Knowledge; Schistosomiasis
1.368
36
Health Policy; Health; Public Health, Environmental and Occupational Health; Epidemiology
Medicine; Social Sciences
2,022
36,175,896
Prognostic value of lymph node density on cancer staging system for gastric cancer without distal metastasis: a population-based analysis of SEER database.
World journal of surgical oncology
World J Surg Oncol
20
1
10.1186/s12957-022-02795-9
eng
2,022
9
29
2,022
9
29
[BACKGROUND] Accurate tumor staging is the cornerstone of tumor treatment. Current tumor staging system for gastric cancer (GC) is based on regional positive lymph nodes while ignoring the total number of examined lymph nodes. We aim to assess the prognostic value of lymph node density (LND), the ratio of positive node...
Cancer-specific survival; Gastric cancer; Lymph node density; Overall survival; SEER; Tumor staging
0.774
82
Surgery; Oncology
Medicine
2,022
36,175,832
Comparative transcriptomic analysis revealed dynamic changes of distinct classes of genes during development of the Manila clam (Ruditapes philippinarum).
BMC genomics
BMC Genomics
23
1
10.1186/s12864-022-08813-0
eng
2,022
9
29
2,022
9
29
[BACKGROUND] The Manila clam Ruditapesphilippinarum is one of the most economically important marine shellfish. However, the molecular mechanisms of early development in Manila clams are largely unknown. In this study, we collected samples from 13 stages of early development in Manila clam and compared the mRNA express...
Different developmental stages; Molecular basis; Ruditapesphilippinarum; Transcriptomics
1.107
208
Biotechnology; Genetics
Biochemistry, Genetics and Molecular Biology
2,022
36,175,758
A Qualitative Study of Perspectives of Older Adults on Deintensifying Diabetes Medications.
Journal of general internal medicine
J Gen Intern Med
38
4
10.1007/s11606-022-07828-3
eng
2,023
3
null
2,022
9
29
[BACKGROUND] While many older adults with type 2 diabetes have tight glycemic control beyond guideline-recommended targets, deintensifying (stopping or dose-reducing) diabetes medications rarely occurs. [OBJECTIVE] To explore the perspectives of older adults with type 2 diabetes around deintensifying diabetes medicatio...
adverse reactions; aging; deprescriptions; diabetes mellitus, type 2; drug-related side effects; hypoglycemia
1.732
224
Internal Medicine
Medicine
2,023
36,175,352
Design considerations for cases used in pharmacy teaching and learning using the case difficulty cube.
Currents in pharmacy teaching learning
Curr Pharm Teach Learn
14
10
10.1016/j.cptl.2022.09.008
eng
2,022
10
null
2,022
9
27
[INTRODUCTION] Learner-centered authentic learning opportunities in health science disciplines can be provided using cases to allow integration of theoretical knowledge across multiple subject areas and development of problem-solving skills. We have previously described the adaptation of the case difficulty cube (CDC),...
Assessment; Case difficulty; Cases
null
null
null
null
null
36,175,340
Medial prefrontal cortex nitric oxide modulates neuropathic pain behavior through mu opioid receptors in rats.
The Korean journal of pain
Korean J Pain
35
4
10.3344/kjp.2022.35.4.413
eng
2,022
10
1
null
null
null
[BACKGROUND] The neocortex, including the medial prefrontal cortex (mPFC), contains many neurons expressing nitric oxide synthase (NOS). In addition, increasing evidence shows that the nitric oxide (NO) and opioid systems interact in the brain. However, there have been no studies on the interaction of the opioid and NO...
Arginine; Hyperalgesia; Narcotic Antagonists; Nitric Oxide; Pain; Prefrontal Cortex; Rats.; Sciatic Nerve
0.618
36
Anesthesiology and Pain Medicine
Medicine
2,022
36,174,994
Early IL-17A Prevention Rather Than Late IL-17A Neutralization Attenuates Toluene Diisocyanate-Induced Mixed Granulocytic Asthma.
Allergy, asthma immunology research
Allergy Asthma Immunol Res
14
5
10.4168/aair.2022.14.5.528
eng
2,022
9
null
null
null
null
[PURPOSE] Interleukin (IL)-17A plays a critical role in the pathogenesis of allergic airway inflammation. Yet, the exact roles of IL-17A in asthma are still controversial. Thus, the aim of this study was to dissect the roles of IL-17A in toluene diisocyanate (TDI)-induced mixed granulocytic asthma and to assess the eff...
Asthma; IL-17A; dual effects; early intervention; toluene diisocyanate
null
null
null
null
null
36,174,977
Hydrogen sulfide protects from acute kidney injury via attenuating inflammation activated by necroptosis in dogs.
Journal of veterinary science
J Vet Sci
23
5
10.4142/jvs.22064
eng
2,022
9
null
null
null
null
[BACKGROUND] The treatment of acute kidney injury (AKI), a common disease in dogs, is limited. Therefore, an effective method to prevent AKI in veterinary clinics is particularly crucial. [OBJECTIVES] Hydrogen sulfide (H2S) is the third gaseous signal molecule involved in various physiological functions of the body. Th...
Acute kidney injury; dogs; hydrogen sulfide; inflammation; necroptosis
0.403
59
Veterinary
Veterinary
2,022
36,174,911
Profiling of the microbiota of breast milk before and after feeding with an artificial nipple.
Journal of oral biosciences
J Oral Biosci
64
4
10.1016/j.job.2022.09.004
eng
2,022
12
null
2,022
9
26
[OBJECTIVES] Breast milk is a valuable and useful source of nutrition; however, surplus milk is routinely discarded for hygiene reasons despite an unclear scientific basis. Here, we profiled the microbiota of expressed breast milk before and after feeding with an artificial nipple and examined the bacterial survival in...
Bottle feeding; Breast feeding; Microbiology; Microbiota
0.501
29
Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine
Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine
2,022
36,174,463
KLF10 deficiency in CD4[+] T cells promotes atherosclerosis progression by altering macrophage dynamics.
Atherosclerosis
Atherosclerosis
359
null
10.1016/j.atherosclerosis.2022.08.019
eng
2,022
10
null
2,022
9
13
[BACKGROUND AND AIMS] Accumulating evidence supports a critical role for CD4[+] T cells as drivers and modifiers of the chronic inflammatory response in atherosclerosis. Effector T cells have pro-atherogenic properties, whereas CD4[+] regulatory T cells (Tregs) exert suppressive activity in atherosclerosis through incr...
Atherosclerosis; CD4(+) T cell; Inflammation; KLF10; Macrophage; Treg
1.375
201
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,173,628
Economic Analysis of Infectious Disease Consultation for Staphylococcus aureus Bacteremia Among Hospitalized Patients.
JAMA network open
JAMA Netw Open
5
9
10.1001/jamanetworkopen.2022.34186
eng
2,022
9
1
2,022
9
1
[IMPORTANCE] Staphylococcus aureus bacteremia is associated with a significant burden of mortality, morbidity, and health care costs. Infectious disease consultation may be associated with reduced mortality and bacteremia recurrence rates. [OBJECTIVE] To evaluate the cost-effectiveness of infectious disease consultatio...
null
4.108
154
Medicine
Medicine
2,022
36,173,541
DiffeoRaptor: diffeomorphic inter-modal image registration using RaPTOR.
International journal of computer assisted radiology and surgery
Int J Comput Assist Radiol Surg
18
2
10.1007/s11548-022-02749-2
eng
2,023
2
null
2,022
9
29
[PURPOSE] Diffeomorphic image registration is essential in many medical imaging applications. Several registration algorithms of such type have been proposed, but primarily for intra-contrast alignment. Currently, efficient inter-modal/contrast diffeomorphic registration, which is vital in numerous applications, remain...
Diffeomorphism; Geodesic shooting; Image registration; Inter-modal; RaPTOR; SyN
0.853
71
Computer Graphics and Computer-Aided Design; Radiology, Nuclear Medicine and Imaging; Surgery; Biomedical Engineering; Computer Science Applications; Computer Vision and Pattern Recognition; Health Informatics; Medicine
Computer Science; Engineering; Medicine
2,023
36,173,318
Systemic sclerosis associated interstitial lung disease: a conceptual framework for subclinical, clinical and progressive disease.
Rheumatology (Oxford, England)
Rheumatology (Oxford)
62
5
10.1093/rheumatology/keac557
eng
2,023
5
2
null
null
null
[OBJECTIVES] To establish a framework by which experts define disease subsets in systemic sclerosis associated interstitial lung disease (SSc-ILD). [METHODS] A conceptual framework for subclinical, clinical and progressive ILD was provided to 83 experts, asking them to use the framework and classify actual SSc-ILD pati...
systemic sclerosis interstitial lung disease
1.721
205
Pharmacology; Rheumatology
Medicine
2,023
36,173,242
EpiSmart Crosslinking for Keratoconus: A Phase 2 Study.
Cornea
Cornea
42
7
10.1097/ICO.0000000000003136
eng
2,023
7
1
2,022
9
28
[PURPOSE] The aim of this study was to assess changes in visual acuity after epithelium-on ("epi-on") corneal crosslinking after a diagnosis of keratoconus. [METHODS] Subjects with corneal ectatic diseases were enrolled in a prospective, randomized, controlled, open-label, multicenter trial. Subjects were randomized to...
null
1.019
141
Ophthalmology
Medicine
2,023
36,173,223
Assessment of dietary nutrient intake and its relationship to the nutritional status of children with congenital heart disease in Guangdong province of China.
Asia Pacific journal of clinical nutrition
Asia Pac J Clin Nutr
31
3
10.6133/apjcn.202209_31(3).0019
eng
2,022
null
null
null
null
null
[BACKGROUND AND OBJECTIVES] Congenital heart disease (CHD) is the common congenital malformations in children and cause malnutrition. We determine the association between dietary nutrient intake and nutritional status of children with CHD. [METHODS AND STUDY DESIGN] 428 children of age 1-10 years with CHD admitted. The...
null
null
null
null
null
null
36,173,135
Adolescent Marathon Training: Prospective Evaluation of Musculotendinous Changes During a 6-Month Endurance Running Program.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
J Ultrasound Med
42
5
10.1002/jum.16105
eng
2,023
5
null
2,022
9
29
[OBJECTIVES] Assess changes in lower extremity musculotendinous thickness, tissue echogenicity, and muscle pennation angles among adolescent runners enrolled in a 6-month distance running program. [METHODS] We conducted prospective evaluations of adolescent runners' lower extremity musculotendinous changes at three tim...
hypertrophy; intrinsic foot muscles; lower extremity; running; ultrasound imaging
0.607
108
Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine
2,023
36,172,623
Old Age is an Independent Risk Factor for Pneumonia Development in Patients with SARS-CoV-2 Omicron Variant Infection and a History of Inactivated Vaccine Injection.
Infection and drug resistance
Infect Drug Resist
15
null
10.2147/IDR.S380005
eng
2,022
null
null
2,022
9
21
[OBJECTIVE] Analyzing the risk factors for pneumonia development in breakthrough cases with a history of inactivated vaccine injection is important. The present study aimed to investigate the risk factors for pneumonia development during Omicron variant infection. [DESIGN AND METHODS] The clinical data were retrospecti...
COVID-19; Omicron; SARS-CoV-2; glucose; pneumonia
0.84
74
Infectious Diseases; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,172,231
The relationship between religious/spiritual well-being, psychiatric symptoms and addictive behaviors among young adults during the COVID-19-pandemic.
Frontiers in psychology
Front Psychol
13
null
10.3389/fpsyg.2022.942149
eng
2,022
null
null
2,022
9
12
[BACKGROUND] It is becoming increasingly apparent that the COVID-19 pandemic not only poses risks to physical health, but that it also might lead to a global mental health crisis, making the exploration of protective factors for mental well-being highly relevant. The present study seeks to investigate religious/spiritu...
COVID-19; addictive behavior; mental health; religious/spiritual well-being; young adults
0.891
212
Psychology
Psychology
2,022
36,172,105
Screening of plasma exosomal lncRNAs to identify potential biomarkers for obstructive sleep apnea.
Annals of translational medicine
Ann Transl Med
10
17
10.21037/atm-22-3818
eng
2,022
9
null
null
null
null
[BACKGROUND] Obstructive sleep apnea (OSA) is highly prevalent, but frequently undiagnosed. The existing biomarkers of OSA are relatively insensitive and inaccurate. Long non-coding RNAs (lncRNAs) have no protein-coding ability but have a role in regulating gene expression. They are stably expressed in exosomes, easily...
ENST00000592016; Obstructive sleep apnea (OSA); biomarkers; exosomes; long non-coding RNAs (lncRNAs)
null
null
null
null
null
36,172,090
Rutaecarpine prevents the malignant biological properties of breast cancer cells by the miR-149-3p/S100A4 axis.
Annals of translational medicine
Ann Transl Med
10
17
10.21037/atm-22-3765
eng
2,022
9
null
null
null
null
[BACKGROUND] Breast cancer (BC) is a frequent malignancy that endangers women's health, and its fatality rate ranks 1st among female malignancies. Research has shown that rutaecarpine (RUT), which is a Chinese herbal medicine, blocks the proliferation of cancer cells by a variety of molecular mechanisms. However, the p...
Rutaecarpine (RUT); S100A4; breast cancer (BC); miR-149-3p
null
null
null
null
null
36,172,003
Effects of high-absorption curcumin for the prevention of hypertensive heart disease: a double-blind, placebo-controlled, randomized clinical study.
European heart journal open
Eur Heart J Open
2
5
10.1093/ehjopen/oeac057
eng
2,022
9
null
2,022
9
10
[AIMS] Hypertension is a strong risk factor for heart failure with preserved ejection fraction. Curcumin has p300-specific histone acetyltransferase inhibitory activity, suppresses cardiomyocyte hypertrophy and fibrosis, and significantly reduces myocardial brain natriuretic peptide (BNP) expression without altering bl...
B-type natriuretic peptide; Cardiac hypertrophy; Curcumin; Diastolic dysfunction; Hypertension; Prevention
null
null
null
null
null
36,171,561
Non-specific symptoms and post-treatment Lyme disease syndrome in patients with Lyme borreliosis: a prospective cohort study in Belgium (2016-2020).
BMC infectious diseases
BMC Infect Dis
22
1
10.1186/s12879-022-07686-8
eng
2,022
9
28
2,022
9
28
[BACKGROUND] Patients with Lyme borreliosis (LB) may report persisting non-specific symptoms such as fatigue, widespread musculoskeletal pain or cognitive difficulties. When present for more than 6 months and causing a reduction in daily activities, this is often referred to as post-treatment Lyme disease syndrome (PTL...
Disseminated Lyme borreliosis; Erythema migrans; Lyme borreliosis; Persisting non-specific symptoms; Post-treatment Lyme disease syndrome
1.055
137
Infectious Diseases
Medicine
2,022
36,171,525
In vitro evaluation of fissure sealants' wear under erosive, abrasive and erosive/abrasive conditions.
European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry
Eur Arch Paediatr Dent
24
1
10.1007/s40368-022-00757-z
eng
2,023
2
null
2,022
9
28
[PURPOSE] To evaluate and compare the wear of selected resin-based fissure sealants with different compositions properties under erosive, abrasive, and erosive/abrasive conditions. [METHODS] Forty-five samples of the following resin-based fissure sealants were prepared: Fissurit (fluoride free), Fissurit F (with fluori...
Abrasive challenge; Erosive challenge; Fillers; Fissure sealants; Material wear
0.729
55
Dentistry; Pediatrics, Perinatology and Child Health
Dentistry; Medicine
2,023
36,171,074
Predefibrillation end-tidal CO2 and defibrillation success in out-of-hospital cardiac arrest: an observational cohort study.
Emergency medicine journal : EMJ
Emerg Med J
40
1
10.1136/emermed-2021-211951
eng
2,023
1
null
2,022
9
28
[BACKGROUND] Predefibrillation end-tidal CO2 (ETCO2) may predict defibrillation success and could guide defibrillation timing in ventricular fibrillation (VF) cardiac arrest. This relationship has only been studied using advanced airways. Our aim was to evaluate this relationship using both basic (bag-valve-mask (BVM))...
airway; resuscitation
0.956
100
Critical Care and Intensive Care Medicine; Emergency Medicine; Medicine
Medicine
2,023
36,171,044
Efficacy and safety of non-pharmacological interventions for neonatal pain: an overview of systematic reviews.
BMJ open
BMJ Open
12
9
10.1136/bmjopen-2022-062296
eng
2,022
9
28
2,022
9
28
[OBJECTIVES] To synthesise current evidence from systematic reviews (SRs) regarding the efficacy and safety of non-pharmacological interventions to prevent and treat pain in newborn infants. [DESIGN] Overview of SRs. [DATA SOURCES] We searched PubMed, Embase, Cochrane Library, Web of Science, CINAHL, Chinese National K...
NEONATOLOGY; Neonatal intensive critical care; PAIN MANAGEMENT
1.059
176
Medicine
Medicine
2,022
36,170,299
Expression of periodontitis susceptibility genes in human gingiva using single-cell RNA sequencing.
Journal of periodontal research
J Periodontal Res
57
6
10.1111/jre.13057
eng
2,022
12
null
2,022
9
28
[OBJECTIVE] Single-cell transcriptomics was used to determine the possible cell-type specificity of periodontitis susceptibility genes. [BACKGROUND] The last decade has witnessed remarkable advances in the field of human genomics. Despite many advances, the genetic factors associated with or contributing to the periodo...
genetics; pathogenesis; periodontitis; single-cell RNA sequencing
0.816
102
Periodontics
Dentistry
2,022
36,169,642
Stability testing of gadoteridol and gadobenate dimeglumine formulations under exposure to high-intensity focused ultrasound.
The British journal of radiology
Br J Radiol
95
1140
10.1259/bjr.20220619
eng
2,022
12
1
2,022
10
14
[OBJECTIVE] Contrast-enhanced MRI could be useful to guide high-intensity focused ultrasound treatment (HIFU), but the effects of HIFU on gadolinium-based agents is not known. Here, we tested in vitro the stability of gadoteridol and gadobenate dimeglumine, two widely used MR contrast agents, after exposure to HIFU at ...
null
0.757
128
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
36,169,353
Formal Closure of Endoscopic Endonasal Skull Base Defects With a "Bow Tie" Tri-Layer Graft.
The Laryngoscope
Laryngoscope
133
7
10.1002/lary.30407
eng
2,023
7
null
2,022
9
28
[OBJECTIVE] Risk factors for a postoperative cerebrospinal fluid leak (CSF) after surgery include an intraoperative high flow of CSF, elevated body mass index, defect size, and defect site. In our prior series, a high postoperative CSF leak rate for tumors of the central skull base (planum, sella, and clivus) appeared ...
CSF leak; bilayer button; cerebrospinal leak; endoscopic; expanded endonasal; gasket seal graft; nasal septal flap; nasoseptal flap; pituitary surgery; skull base defect
1.128
183
Otorhinolaryngology
Medicine
2,023
36,169,280
Residual disease activity and treatment intensification in systemic lupus erythematosus: A cross-sectional study to quantify the need for new therapies.
Lupus
Lupus
31
14
10.1177/09612033221129776
eng
2,022
12
null
2,022
9
28
[OBJECTIVE] The proportion of SLE patients with residual disease activity in routine settings is variable. We assessed disease activity state in patients during their most recent visit, and whether patients with residual activity were offered therapy intensification. [METHODS] Cross-sectional study of consecutive lupus...
disease activity; systemic lupus erythematosus; treatment intensification
0.822
122
Rheumatology
Medicine
2,022
36,168,181
Rates of Missed Injuries in the Prehospital Setting Are Unrelated to the Gender of the Medical Provider: A Retrospective Study.
The Israel Medical Association journal : IMAJ
Isr Med Assoc J
24
9
null
eng
2,022
9
null
null
null
null
[BACKGROUND] Medical organizations worldwide aim for equity and diversity in the medical profession to improve care quality. Data on whether the caregiver gender affects outcomes in the prehospital setting are essential but scarce compared to available in-hospital studies. [OBJECTIVES] To analyze the rates of missed in...
null
null
null
null
null
null
36,167,949
Evaluation of Levetiracetam Dosing Strategies for Seizure Prophylaxis Following Traumatic Brain Injury.
Neurocritical care
Neurocrit Care
38
2
10.1007/s12028-022-01599-9
eng
2,023
4
null
2,022
9
27
[BACKGROUND] Although levetiracetam has been increasingly used as an alternative to phenytoin for early posttraumatic seizure prophylaxis following traumatic brain injury (TBI), an optimal dosing strategy has not been elucidated. The objective of this study is to determine whether different dosing strategies of levetir...
Antiepileptic drugs; Early posttraumatic seizures; Traumatic brain injury
1.104
97
Critical Care and Intensive Care Medicine; Neurology
Medicine
2,023
36,167,689
A retrospective review of patients who sustained traumatic brain injury in Ireland 2014-2019.
Injury
Injury
53
11
10.1016/j.injury.2022.09.013
eng
2,022
11
null
2,022
9
13
[INTRODUCTION] Traumatic brain injury (TBI) is the most significant cause of death and disability resulting from major trauma. The aim of this study is to describe the demographics of TBI patients, the current pathways of care and outcomes in the Republic of Ireland from 2014 to 2019. [METHODS] We performed a retrospec...
Brain injury; Neurosurgery; Trauma; Trauma systems
0.698
151
Surgery; Emergency Medicine; Orthopedics and Sports Medicine
Medicine
2,022
36,167,680
Circular RNA hsa_circ_0000915 promotes propranolol resistance of hemangioma stem cells in infantile haemangiomas.
Human genomics
Hum Genomics
16
1
10.1186/s40246-022-00416-w
eng
2,022
9
27
2,022
9
27
[BACKGROUND] Propranolol is a first-line clinical drug for infantile haemangiomas (IH) therapy. Nevertheless, resistance to propranolol is observed in some patients with IH. Circular RNAs (circRNAs) has been increasingly reported to act as a pivotal regulator in tumor progression. However, the underlying mechanism of c...
Circ_0000915; Infantile haemangiomas; Propranolol resistance; RNF187; miR-890
1.308
73
Drug Discovery; Genetics; Molecular Medicine; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
2,022
36,167,504
Risk stratification and pathway analysis based on graph neural network and interpretable algorithm.
BMC bioinformatics
BMC Bioinformatics
23
1
10.1186/s12859-022-04950-1
eng
2,022
9
27
2,022
9
27
[BACKGROUND] Pathway-based analysis of transcriptomic data has shown greater stability and better performance than traditional gene-based analysis. Until now, some pathway-based deep learning models have been developed for bioinformatic analysis, but these models have not fully considered the topological features of pa...
Deep learning; Graph neural network; Interpretability; Pathway; Risk classification
1.1
251
Applied Mathematics; Biochemistry; Computer Science Applications; Molecular Biology; Structural Biology
Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics
2,022
36,167,413
Load-dependent inverted U-shaped connectivity of the default mode network in schizophrenia during a working-memory task: evidence from a replication functional MRI study.
Journal of psychiatry neuroscience : JPN
J Psychiatry Neurosci
47
5
10.1503/jpn.220053
eng
2,022
null
null
2,022
9
27
[BACKGROUND] Working-memory deficit is associated with aberrant degree distribution of the brain connectome in schizophrenia. However, the brain neural mechanism underlying the degree redistribution pattern in schizophrenia is still uncertain. [METHODS] We examined the functional degree distribution of the connectome i...
null
null
null
null
null
null
36,167,252
Association of Virtual Interviews With Residency Application Geographic Diversity and Match.
Academic pediatrics
Acad Pediatr
23
5
10.1016/j.acap.2022.09.016
eng
2,023
7
null
2,022
9
24
[OBJECTIVE] We sought to assess whether the change from in-person to virtual interviews was associated with differences in applicant and match location geography. [METHODS] We conducted a retrospective study of all U.S. applicants to a large pediatric residency. Distances from applicants to our residency program (appli...
diversity; geography; recruitment; workforce
1.241
99
Pediatrics, Perinatology and Child Health
Medicine
2,023
36,166,959
Emotional arousal in patients with functional movement disorders: A pupillometry study.
Journal of psychosomatic research
J Psychosom Res
162
null
10.1016/j.jpsychores.2022.111043
eng
2,022
11
null
2,022
9
16
[OBJECTIVE] Pathophysiology explanations for functional movement disorders often assume a role for emotional hyperarousal. Pupillometry is a validated method for evaluation of emotional arousal by detecting changes in pupil size in response to emotional stimuli. In a case-control study design, we aimed to study objecti...
Affective ratings; Conversion disorder; Emotional arousal; Motor functional neurological disorder; Pupillometry; Scanpath
1.131
182
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
36,166,516
Race Differences in Patient-Reported Symptoms during Chemotherapy among Women with Early-Stage Hormone Receptor-Positive Breast Cancer.
Cancer epidemiology, biomarkers prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Cancer Epidemiol Biomarkers Prev
32
2
10.1158/1055-9965.EPI-22-0692
eng
2,023
2
6
null
null
null
[BACKGROUND] Symptom burden differences may contribute to racial disparities in breast cancer survival. We compared symptom changes from before to during chemotherapy among women with breast cancer. [METHODS] This observational study followed a cohort of Black and White women diagnosed with Stage I-III, hormone recepto...
null
null
null
null
null
null
36,166,472
Cost-Effectiveness of Colorectal Cancer Surveillance in Hodgkin Lymphoma Survivors Treated with Procarbazine and/or Infradiaphragmatic Radiotherapy.
Cancer epidemiology, biomarkers prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Cancer Epidemiol Biomarkers Prev
31
12
10.1158/1055-9965.EPI-22-0019
eng
2,022
12
5
null
null
null
[BACKGROUND] Hodgkin lymphoma survivors treated with infradiaphragmatic radiotherapy (IRT) and/or procarbazine have an increased risk of developing colorectal cancer. We investigated the cost-effectiveness of colorectal cancer surveillance in Dutch Hodgkin lymphoma survivors to determine the optimal surveillance strate...
null
null
null
null
null
null
36,166,285
Trends in Effectiveness of Organizational eHealth Interventions in Addressing Employee Mental Health: Systematic Review and Meta-analysis.
Journal of medical Internet research
J Med Internet Res
24
9
10.2196/37776
eng
2,022
9
27
2,022
9
27
[BACKGROUND] Mental health conditions are considered the leading cause of disability, sickness absence, and long-term work incapacity. eHealth interventions provide employees with access to psychological assistance. There has been widespread implementation and provision of eHealth interventions in the workplace as an i...
eHealth; employee; mental health; mobile phone; systematic review
1.992
214
Health Informatics
Medicine
2,022
36,166,152
OCT-Based Biomarkers are Associated with Systemic Inflammation in Patients with Treatment-Naïve Diabetic Macular Edema.
Ophthalmology and therapy
Ophthalmol Ther
11
6
10.1007/s40123-022-00576-x
eng
2,022
12
null
2,022
9
27
[INTRODUCTION] Diabetic macular edema (DME) is one of the major sight-threatening complications of diabetic retinopathy, which is associated with retinal inflammation. However, it is still unknown whether DME is associated with systemic inflammation. The study aimed to investigate the association between systemic infla...
Biomarker; Diabetic macular edema; Inflammation; Optical coherence tomography
1.02
42
Ophthalmology
Medicine
2,022
36,165,979
Intraoral Repair of Chipping Due to Cohesive Failure-Results of a Nationwide Survey Among Dentists in Germany.
The International journal of prosthodontics
Int J Prosthodont
36
2
10.11607/ijp.7098
eng
2,023
5
null
2,023
5
24
[PURPOSE] To survey the materials favored by dentists for intraoral repair of cohesive chipping. [MATERIALS AND METHODS] From August 2019 to February 2020, dentists were surveyed to determine the frequency of cohesive chipping experienced within the last 3 months and to identify their preferred approaches for intraoral...
null
0.746
110
Oral Surgery; Medicine
Dentistry; Medicine
2,023
36,165,904
The use of crista galli morphology and morphometry in sex determination: a cone-beam computed tomography study.
Folia morphologica
Folia Morphol (Warsz)
81
4
10.5603/FM.a2022.0077
eng
2,022
null
null
2,022
9
27
[BACKGROUND] The morphology of crista galli (CG) varies from one individual to another and its structure may be pneumatized or compact bone. This study purposed to investigate the morphometry of the CG on cone-beam computed tomography (CBCT) scans, to apply morphological classification based on the characteristics of t...
cone-beam computed tomography; crista galli; morphology; olfactory fossa; pneumatization; sex determination
0.304
39
Anatomy; Histology
Medicine
2,022
36,165,511
Identification of key modules and hub genes for eosinophilic asthma by weighted gene co-expression network analysis.
The Journal of asthma : official journal of the Association for the Care of Asthma
J Asthma
60
5
10.1080/02770903.2022.2128372
eng
2,023
5
null
2,022
10
6
[OBJECTIVE] Eosinophilic asthma (EA) is one of the most important asthma phenotypes with distinct features. However, its genetic characteristics are not fully understood. This study aimed to investigate the transcriptome features and to identify hub genes of EA. [METHODS] Differentially expressed genes (DEGs) analysis,...
Eosinophilic asthma; WGCNA; gene expression; hub genes
0.609
80
Medicine; Pediatrics, Perinatology and Child Health; Pulmonary and Respiratory Medicine; Immunology and Allergy
Medicine
2,023
36,165,497
A Cross-Sectional Descriptive Analysis of Diversity, Equity, and Inclusion Presence Among United States Occupational and Environmental Medicine Residency Program Websites.
Journal of occupational and environmental medicine
J Occup Environ Med
65
3
10.1097/JOM.0000000000002714
eng
2,023
3
1
2,022
9
27
[OBJECTIVE] To evaluate the presence of diversity, equity, and inclusion (DEI) among US occupational and environmental medicine (OEM) residency program websites. [METHODS] In January to February 2022, two independent reviewers evaluated the websites of all 24 US accredited OEM residency programs and documented the pres...
null
0.714
130
Public Health, Environmental and Occupational Health
Medicine
2,023
36,164,949
Cross-sectional analysis of tobacco addiction in hospitalized COVID-19 patients.
Tuberkuloz ve toraks
Tuberk Toraks
70
3
10.5578/tt.20229704
eng
2,022
9
null
null
null
null
[INTRODUCTION] The COVID-19 pandemic has become an important health issue with consequences for special populations since 2019. Tobacco use is an important public health issue and tobacco users are a risk group for lung infections. [MATERIALS AND METHODS] The aim of this study is to obtain information about disease pre...
null
null
null
null
null
null
36,164,772
Racial Differences in Emergency Department Visit Characteristics and Management of Preadolescents at Risk of Suicide.
Psychiatric services (Washington, D.C.)
Psychiatr Serv
74
3
10.1176/appi.ps.202100608
eng
2,023
3
1
2,022
9
27
[OBJECTIVE] Suicide rates and frequency of pediatric emergency department (ED) visits for suicidal thoughts and behaviors have increased among Black preadolescents in the United States in recent years. This study examined whether characteristics of ED visits and treatment management of preadolescents with suicidal thou...
Black children; Child psychiatry/general; Emergency psychiatry; emergency department; preadolescents; suicide prevention
1.543
174
Medicine; Psychiatry and Mental Health
Medicine
2,023
36,164,629
Serum Caveolin-1 Level is Inversely Associated with Serum Vaspin, Visfatin, and HbA1c in Newly Diagnosed Men with Type-2 Diabetes.
Reports of biochemistry molecular biology
Rep Biochem Mol Biol
11
2
10.52547/rbmb.11.2.299
eng
2,022
7
null
null
null
null
[BACKGROUND] The fluctuation in serum caveolin-1 (Cav-1) concentrations is an important indicator of many diseases. Irrespective of the actual cause, a significant reduction of serum Cav-1 is associated with a significant increase in insulin secretion and hyperinsulinemia. The aim of the current study was to evaluate t...
Caveolin-1; HbA1c; Insulin resistance; T2DM; Vaspin; Visfatin
null
null
null
null
null
36,164,406
Radiographic factors associated with inferior alveolar nerve exposure during mandibular third molar surgery and their influence on neurosensory deficit: A prospective study.
Journal of oral biology and craniofacial research
J Oral Biol Craniofac Res
12
6
10.1016/j.jobcr.2022.08.025
eng
2,022
null
null
2,022
9
10
[INTRODUCTION] The inferior alveolar nerve (IAN) can occasionally be observed in the extraction socket of the mandibular third molar (M3M) intraoperatively. Exposure of inferior alveolar neurovascular bundle during surgery primarily depends upon the absence of bony cortex between the canal and root of impacted third mo...
Cone beam computed; Cone beam computed tomography, CBCT; Cortex of inferior alveolar canal; Impacted mandibular third molar; Mandibular third molar, M3M; Nerve exposure; Orthopantomography; Orthopantomography, Panoramic radiography, OPG; Paresthesia; Tomography
0.475
39
Dentistry; Otorhinolaryngology
Dentistry; Medicine
2,022
36,163,696
Predictors of histologic response to dietary therapy in eosinophilic oesophagitis.
Alimentary pharmacology therapeutics
Aliment Pharmacol Ther
56
10
10.1111/apt.17221
eng
2,022
11
null
2,022
9
26
[BACKGROUND] Dietary therapy successfully treats eosinophilic oesophagitis (EoE), but limited data exist on predictors of patient response. [AIMS] To determine response rates and to identify predictors of histologic response to elimination diets in adults with EoE METHODS: This was a retrospective, single-centre study ...
dietary therapy; eosinophilic oesophagitis; oesophagitis; oesophagus
null
null
null
null
null
36,163,686
Suicidality and relief of depressive symptoms with intermittent theta burst stimulation in a sham-controlled randomized clinical trial.
Acta psychiatrica Scandinavica
Acta Psychiatr Scand
146
6
10.1111/acps.13502
eng
2,022
12
null
2,022
10
14
[OBJECTIVES] Suicidality is a serious public health problem and is closely associated with the severity of depression. In this work, we examined the effects of accelerated intermittent theta burst stimulation (iTBS) on suicidal status, risk factors for suicide, and severity of depressive symptoms in subjects with major...
Columbia Suicidality Rating Scale; accelerated intermittent theta burst; anti-suicide effect; antidepressant effect; randomized clinical trial
2.444
174
Psychiatry and Mental Health
Medicine
2,022
36,163,646
How to assess, detect, and manage joint involvement in the era of transformational therapies: Role of point-of-care ultrasound.
Haemophilia : the official journal of the World Federation of Hemophilia
Haemophilia
29
1
10.1111/hae.14657
eng
2,023
1
null
2,022
9
26
[BACKGROUND] Patients with haemophilia experience recurring hemarthroses, mainly involving knees, elbows and ankles, which lead to haemophilic arthropathy, the major chronic complication of haemophilia. With new approaches to haemophilia treatment leading to fewer joint bleeds and, in some cases, no bleeding events, as...
haemarthrosis; haemophilia A; haemorrhage; joint diseases; ultrasound
1.316
107
Genetics; Hematology; Medicine
Medicine
2,023
36,163,203
Effects of sequential aeromedical evacuations following traumatic brain injury in swine.
Injury
Injury
53
11
10.1016/j.injury.2022.09.004
eng
2,022
11
null
2,022
9
15
[INTRODUCTION] Traumatic brain injuries (TBI) represent a significant percentage of critical injuries in military conflicts. Following injury, wounded warfighters are often subjected to multiple aeromedical evacuations (AE) and associated hypobaria, yet the impact in TBI patients remains to be characterized. This study...
Aeromedical evacuation; Fluid-percussion injury; Hypobaria; Inflammation; TBI
0.698
151
Surgery; Emergency Medicine; Orthopedics and Sports Medicine
Medicine
2,022
36,163,177
Long noncoding RNA TUG1 induces angiogenesis of endothelial progenitor cells and dissolution of deep vein thrombosis.
Thrombosis journal
Thromb J
20
1
10.1186/s12959-022-00413-y
eng
2,022
9
26
2,022
9
26
[OBJECTIVE] Long non-coding RNA (lncRNA) essentially controls many physiological and pathological processes of deep vein thrombosis (DVT). Based on that, lncRNA taurine upregulated gene 1 (TUG1)-involved angiogenesis of endothelial progenitor cells (EPCs) and dissolution of DVT was explored. [METHODS] In the in-vitro e...
3-Hydroxy-3-methylglutaryl coenzyme a reductase; Angiogenesis; Deep vein thrombosis; Endothelial progenitor cells; Long noncoding RNA taurine upregulated gene 1; microRNA-92a-3p
0.699
51
Hematology
Medicine
2,022
36,163,156
Bilateral Ultrasound-Guided Erector Spinae Plane Block for Pectus Excavatum Surgery: A Retrospective Propensity-Score Study.
Journal of cardiothoracic and vascular anesthesia
J Cardiothorac Vasc Anesth
36
12
10.1053/j.jvca.2022.08.018
eng
2,022
12
null
2,022
8
27
[OBJECTIVE] Pectus excavatum (PE) repair is burdened by severe postoperative pain. This retrospective study aimed to determine whether the analgesic effect of ultrasound-guided erector spinae plane block (ESPB) plus standard intravenous analgesia (SIVA) might be superior to SIVA alone in pain control after PE surgical ...
Nuss procedure; Ravitch procedure; erector spinae plane block; pectus excavatum surgery; regional anesthesia; thoracic anesthesia
0.694
100
Anesthesiology and Pain Medicine; Cardiology and Cardiovascular Medicine
Medicine
2,022
36,163,043
Seasonal responses and host uniqueness of gut microbiome of Japanese macaques in lowland Yakushima.
Animal microbiome
Anim Microbiome
4
1
10.1186/s42523-022-00205-9
eng
2,022
9
27
2,022
9
27
[BACKGROUND] Changes in the gut microbial composition is an important response to cope with the seasonal fluctuations in the environment such as food availability. We examined the bacterial gut microbiome of the wild nonhuman primate, Japanese macaque (Macaca fuscata) in Yakushima over 13 months by noninvasive continuo...
16S rRNA; Diet shift; Food intake; Gut bacteria; Nonhuman primates; Wild animal
null
null
null
null
null
36,162,980
Nonlinear relationship with saturation effect observed between neutrophil to high-density lipoprotein cholesterol ratio and atherosclerosis in a health examination population: a cross-sectional study.
BMC cardiovascular disorders
BMC Cardiovasc Disord
22
1
10.1186/s12872-022-02869-2
eng
2,022
9
26
2,022
9
26
[BACKGROUND] The relationships between inflammatory indexes and atherosclerosis as well as those between blood lipid indexes and atherosclerosis have been widely studied, but the relationship between the neutrophil to high-density lipoprotein cholesterol ratio (NHR) and atherosclerosis had not been investigated until t...
Atherosclerosis; Ba-PWV; Brachial-ankle pulse wave velocity; NHR
0.601
76
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,162,898
FINDINGS AND FUTURE DIRECTIONS FROM A SMOKING CESSATION TRIAL UTILIZING A CLINICAL DECISION SUPPORT TOOL.
The journal of evidence-based dental practice
J Evid Based Dent Pract
22
3
10.1016/j.jebdp.2022.101747
eng
2,022
9
null
2,022
5
20
[BACKGROUND] Tobacco smoking is the leading cause of disease, death, and disability in the United States. Dental practitioners are advised to provide evidence-based smoking cessation interventions to their patients, yet dental practitioners frequently fail to deliver brief smoking cessation advice. [OBJECTIVES] To test...
Decision support systems, clinical; Dental hygienists; Dentists; Randomized controlled trials; Smoking cessation
0.869
45
Dentistry
Dentistry
2,022
36,162,823
Effects of writers, erasers and readers within miRNA-related m6A modification in cancers.
Cell proliferation
Cell Prolif
56
1
10.1111/cpr.13340
eng
2,023
1
null
2,022
9
26
[BACKGROUND] As one of the most abundant post-transcriptional mRNA modifications, N6-methyladenosine (m6A) has attracted extensive attention from scientists. Emerging evidence indicates that m6A modification plays a significant role in cancer-related signalling pathways. Existing research demonstrates that m6A modifica...
null
1.951
102
Cell Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,162,806
Disentangling the influences of parental genetics on offspring's cognition, education, and psychopathology via genetic and phenotypic pathways.
Journal of child psychology and psychiatry, and allied disciplines
J Child Psychol Psychiatry
64
3
10.1111/jcpp.13708
eng
2,023
3
null
2,022
9
26
[BACKGROUND] Specific pathways of intergenerational transmission of behavioral traits remain unclear. Here, we aim to investigate how parental genetics influence offspring cognition, educational attainment, and psychopathology in youth. [METHODS] Participants for the discovery sample were 2,189 offspring (aged 6-14 yea...
Genetics; cognition; educational attainment; gene-environment correlation; intergenerational transmission; polygenic scores
3.133
252
Developmental and Educational Psychology; Pediatrics, Perinatology and Child Health; Psychiatry and Mental Health
Medicine; Psychology
2,023
36,162,652
Pre-partum HRV as a predictor of postpartum depression: The potential use of a smartphone application for physiological recordings.
Journal of affective disorders
J Affect Disord
319
null
10.1016/j.jad.2022.09.056
eng
2,022
12
15
2,022
9
23
[BACKGROUND] This study aimed to investigate the role of a time-domain Heart Rate Variability index (the root mean square of successive difference between NN intervals, rMSSD) as a predictor of the onset of postpartum depression. HRV has been related to an increased risk of depression in the general population. However...
Depressive symptoms; Heart rate variability; Postpartum depression; Pregnancy; Smartphone application
1.988
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
36,162,063
Effect of Single Housing on Innate Immune Activation in Immunodeficiency Virus-Infected Pigtail Macaques (Macaca nemestrina) as a Model of Psychosocial Stress in Acute HIV Infection.
Psychosomatic medicine
Psychosom Med
84
8
10.1097/PSY.0000000000001132
eng
2,022
10
1
2,022
9
7
[OBJECTIVE] Simian immunodeficiency virus (SIV) infection of macaques recapitulates many aspects of HIV pathogenesis and is similarly affected by both genetic and environmental factors. Psychosocial stress is associated with immune system dysregulation and worse clinical outcomes in people with HIV. This study assessed...
null
1.105
214
Developmental and Educational Psychology; Psychiatry and Mental Health; Applied Psychology
Medicine; Psychology
2,022
36,161,999
CLINICAL CHARACTERISTICS AND PROGNOSTIC FACTORS AFFECTING CLINICAL OUTCOMES IN CYTOMEGALOVIRUS RETINITIS WITH OR WITHOUT HIV INFECTION.
Retina (Philadelphia, Pa.)
Retina
43
1
10.1097/IAE.0000000000003631
eng
2,023
1
1
null
null
null
[PURPOSE] To explore the clinical features and outcomes of cytomegalovirus retinitis (CMVR) in patients with HIV and non-HIV. [METHODS] This retrospective cohort study included all patients with CMVR in National Taiwan University Hospital from 2013 to 2018. Demographic data, clinical characteristics, CMVR recurrence, a...
null
1.214
149
Medicine; Ophthalmology
Medicine
2,023
36,161,845
Screen time and its correlates among children aged 3-10 years during COVID-19 pandemic in Nepal: a community-based cross-sectional study.
BMJ open ophthalmology
BMJ Open Ophthalmol
7
1
10.1136/bmjophth-2022-001052
eng
2,022
8
null
null
null
null
[OBJECTIVE] This study aims to determine the prevalence of high screen time among schoolchildren aged 3-10 years in Bhaktapur, its correlates and the parents' strategies to reduce screen time during the COVID-19 pandemic in Nepal. [METHODS AND ANALYSIS] This cross-sectional descriptive study was conducted during March ...
COVID-19; Child health (paediatrics); Public health
0.913
28
Ophthalmology
Medicine
2,022
36,161,207
Factors associated with medication non-adherence among patients with severe mental disorder - A cross sectional study in a tertiary care centre.
Exploratory research in clinical and social pharmacy
Explor Res Clin Soc Pharm
7
null
10.1016/j.rcsop.2022.100178
eng
2,022
9
null
2,022
9
12
[BACKGROUND] Medications are an essential treatment modality of mental disorders. There is limited scientific literature on medication non-adherence among patients in Severe Mental Disorders with respect to patient-related factors. The current study explores the factors associated with medication non-adherence in such ...
Attitude; Caregiver; Medication adherence; Mental disorders; Psychotropics; Stigma
null
12
Health, Toxicology and Mutagenesis; Pharmacology; Pharmacy
Environmental Science; Health Professions; Medicine
2,022
36,161,101
MiR-495-3p depletion contributes to myocardial ischemia/reperfusion injury in cardiomyocytes by targeting TNC.
Regenerative therapy
Regen Ther
21
null
10.1016/j.reth.2022.08.007
eng
2,022
12
null
2,022
9
12
[BACKGROUND] Tenascin-C (TNC) has been found to abnormally express in myocardial ischemia/reperfusion injury (MI/RI), but its effect on cardiomyocytes apoptosis is unknown and is worthy of investigation. [METHODS] H9C2 cells were given hypoxia/reoxygenation (H/R) treatment to obtain the replica of MI/RI in vitro. The e...
Apoptosis; Ca2+ overload; Inflammation; Myocardial ischemia/reperfusion injury; Tenascin-C; microRNA-495-3p
0.802
37
Biomaterials; Biomedical Engineering; Developmental Biology
Biochemistry, Genetics and Molecular Biology; Engineering; Materials Science
2,022
36,161,064
Workers compensation patients experiencing depression report meaningful improvement in mental health scores after anterior cervical discectomy and fusion.
Journal of clinical orthopaedics and trauma
J Clin Orthop Trauma
34
null
10.1016/j.jcot.2022.102020
eng
2,022
11
null
2,022
9
11
[BACKGROUND] Mental health has been demonstrated to affect postoperative outcomes. No prior literature has reported the relationship between preoperative mental health on outcomes following anterior cervical discectomy and fusion (ACDF) in the Workers Compensation (WC) population. [METHODS] WC claimants who underwent p...
ACDF; MCID; Mental health; PROMs; Workers' compensation
0.508
45
Orthopedics and Sports Medicine
Medicine
2,022
36,160,811
SVEAT score outperforms HEART score in patients admitted to a chest pain observation unit.
World journal of cardiology
World J Cardiol
14
8
10.4330/wjc.v14.i8.454
eng
2,022
8
26
null
null
null
[BACKGROUND] Timely and accurate identification of subgroup at risk for major adverse cardiovascular events among patients presenting with acute chest pain remains a challenge. Currently available risk stratification scores are suboptimal. Recently, a new scoring system called the Symptoms, history of Vascular disease,...
Acute chest pain; Risk stratification tool
null
null
null
null
null
36,160,648
Oxidized low-density lipoprotein stimulates CD206 positive macrophages upregulating CD44 and CD133 expression in colorectal cancer with high-fat diet.
World journal of gastroenterology
World J Gastroenterol
28
34
10.3748/wjg.v28.i34.4993
eng
2,022
9
14
null
null
null
[BACKGROUND] Oxidized low-density lipoprotein (ox-LDL), which is abnormally increased in the serum of colorectal cancer (CRC) patients consuming a high-fat diet (HFD), may be one of the risk factors for the development of CRC. Ox-LDL exerts a regulatory effect on macrophages and may influence CRC through the tumor micr...
CD133; CD206 positive macrophages; CD44; Oxidized low-density lipoprotein
null
null
null
null
null
36,160,539
Can resilience promote calling among Chinese nurses in intensive care units during the COVID-19 pandemic? The mediating role of thriving at work and moderating role of ethical leadership.
Frontiers in psychology
Front Psychol
13
null
10.3389/fpsyg.2022.847536
eng
2,022
null
null
2,022
9
7
[BACKGROUND] Nurses working in the intensive care unit (ICU) clung tenaciously to their job during the COVID-19 pandemic in spite of enduring stressed psychological and physical effects as a result of providing nursing care for the infected patients, which indicates that they possessed a high degree of professionalism ...
COVID-19 pandemic; ICU nurse; calling; ethical leadership; resilience; thriving at work
0.891
212
Psychology
Psychology
2,022
36,160,115
Potential Biomarkers and Signaling Pathways Associated with the Pathogenesis of Primary Ameloblastoma: A Systems Biology Approach.
International journal of dentistry
Int J Dent
2022
null
10.1155/2022/3316313
eng
2,022
null
null
2,022
9
16
[OBJECTIVE] Ameloblastoma is a benign odontogenic tumor that may lead to ameloblastic carcinoma. This study aimed to determine potential signaling pathways and biological processes, critical genes and their regulating transcription factors (TFs), and miRNAs, as well as protein kinases involved in the etiology of primar...
null
0.47
57
Dentistry
Dentistry
2,022
36,159,914
Prescribing behavior of antidepressants for depressive disorders: A systematic review.
Frontiers in psychiatry
Front Psychiatry
13
null
10.3389/fpsyt.2022.918040
eng
2,022
null
null
2,022
9
9
[OBJECTIVE] Guidelines for the prescription of antidepressants for Depressive Disorders (DD) have been in place for a long time. However, there is a lack of systematic information on the prescribing behavior of antidepressants in evidence-based clinical practice in psychopharmacotherapy of depressive disorders. This ma...
antidepressants; depressive disorder; prescribing behavior; psychopharmacotherapy; systematic review
1.222
134
Psychiatry and Mental Health
Medicine
2,022
36,159,901
Nasal vestibular furunculosis: Summarised case series.
World journal of otorhinolaryngology - head and neck surgery
World J Otorhinolaryngol Head Neck Surg
8
3
10.1016/j.wjorl.2020.12.003
eng
2,022
9
null
2,022
5
23
[OBJECTIVE] Nasal vestibular furunculosis (NVF) is characterized by an acute localized infection of the hair follicle in the skin lining of the nasal vestibule. This study provides an up-to-date narrative analysis on NVF, its presentation, complications and management. [METHODS] A literature search was conducted electr...
Furunculosis; Nasal dermatology; Staph aureus
0.567
30
Otorhinolaryngology; Surgery
Medicine
2,022
36,159,877
Causal effects of gut microbiota on diabetic retinopathy: A Mendelian randomization study.
Frontiers in immunology
Front Immunol
13
null
10.3389/fimmu.2022.930318
eng
2,022
null
null
2,022
9
8
[BACKGROUND] Previous researches have implicated a vital association between gut microbiota (GM) and diabetic retinopathy (DR) based on the association of the "gut-retina" axis. But their causal relationship has not been elucidated. [METHODS] Instrumental variables of 211 GM taxa were obtained from genome wide associat...
Mendelian randomization; causality; diabetic retinopathy; gut microbiota; gut-retina axis
2.022
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,022
36,159,564
Deqi Sensation to Predict Acupuncture Effect on Functional Dyspepsia: A Machine Learning Study.
Evidence-based complementary and alternative medicine : eCAM
Evid Based Complement Alternat Med
2022
null
10.1155/2022/4824575
eng
2,022
null
null
2,022
9
14
[OBJECTIVES] The aim of the study was to predict the effect of acupuncture for treating functional dyspepsia (FD) using the support vector machine (SVM) techniques based on initial deqi sensations of patients. [METHODS] This retrospective study involved 90 FD patients who had received four weeks of acupuncture treatmen...
null
null
null
null
null
null