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36,420,208
Radiation Therapy for Relapsed or Refractory Diffuse Large B-Cell Lymphoma: What Is the Right Regimen for Palliation?
Advances in radiation oncology
Adv Radiat Oncol
7
6
10.1016/j.adro.2022.101016
eng
2,022
null
null
2,022
7
3
[PURPOSE] To report objective response rates (ORR), time to local failure (TTLF), and overall survival (OS) among patients with relapsed or refractory diffuse large B-cell lymphoma after salvage- or palliative-intent radiation therapy (RT) and to investigate whether outcomes differed with conventional versus hypofracti...
null
0.791
40
Oncology; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
36,419,876
Pan-cancer analysis of trophinin-associated protein with potential implications in clinical significance, prognosis, and tumor microenvironment in human cancers.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.971618
eng
2,022
null
null
2,022
11
7
[BACKGROUND] Trophinin-associated protein (TROAP), a cytoplasmic protein, is essential for microtubule cytoskeleton assembly. Mounting evidence demonstrates the vital role of TROAP in regulating the proliferation and migration of cells, but it is unclear how it contributes to cancer progression. [METHODS] The online po...
biomarker; immunological; pan-cancer; prognostic; trophinin-associated protein; tumor microenvironment
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,419,763
The effect of different administrations of testosterone therapy on adverse prostate events: A Bayesian network meta-analysis.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
13
null
10.3389/fendo.2022.1009900
eng
2,022
null
null
2,022
11
7
[BACKGROUND] Hypogonadism has become a major cause endangering men's health and quality of life all over the world. Testosterone Therapy (TT) is a widely accepted treatment for relieving hypogonadal symptoms. However, the effect of different administrations of TT on prostate safety is still unclear. [METHODS] We did a ...
administrations; hypogonadism; meta-analysis; prostate safety; systematic review; testosterone therapy
1.278
138
Endocrinology, Diabetes and Metabolism
Medicine
2,022
36,419,745
Professional quality of life among Spanish veterinarians.
Veterinary record open
Vet Rec Open
9
1
10.1002/vro2.50
eng
2,022
12
null
2,022
11
21
[BACKGROUND] In Spain, the perceived professional quality of life among veterinarians has not been explored. [METHODS] Veterinarians were invited to complete an online questionnaire in which they answered the Professional Quality of Life scale, the Medical Outcomes Study Social Support Survey and the Warwick-Edinburgh ...
null
0.506
21
Veterinary
Veterinary
2,022
36,419,456
Testicular Cancer Knowledge and Viewpoints of American Men.
Urology practice
Urol Pract
9
1
10.1097/UPJ.0000000000000267
eng
2,022
1
null
2,021
9
30
[INTRODUCTION] We sought to better understand the baseline knowledge and practices of the general population regarding testicular cancer (TC) and testicular self-examination (TSE) in an effort to understand whether current screening guidelines reflect their viewpoint. The U.S. Preventive Services Task Force (USPSTF) cu...
early detection of cancer; self-examination; testicular neoplasms
0.285
18
Urology
Medicine
2,022
36,419,336
Effect of Diets on Plasma and Aorta Lipidome: A Study in the apoE Knockout Mouse Model.
Molecular nutrition food research
Mol Nutr Food Res
67
2
10.1002/mnfr.202200367
eng
2,023
1
null
2,022
12
5
[SCOPE] Specific lipid molecules circulating in plasma at low concentrations have emerged as biomarkers of atherosclerotic risk. The aim of the present study is that of evaluating, in an athero-prone mouse model, how different diets can affect plasma and aorta lipidome. [METHODS AND RESULTS] Thirty-six apoE knockout mi...
aorta; atherosclerosis; cholesterol; lipidomics; mouse models
null
null
null
null
null
36,419,190
Clinical improvement of sepsis by extracorporeal centrifugal leukocyte apheresis in a porcine model.
Journal of translational medicine
J Transl Med
20
1
10.1186/s12967-022-03752-6
eng
2,022
11
22
2,022
11
22
[BACKGROUND] Extracorporeal blood purification therapies targeting removal of the downstream products of the inflammatory cascade in sepsis have failed to improve mortality. As an upstream process of the inflammatory cascade, activated white blood cells should be a potential therapeutic target for sepsis, and the effec...
Extracorporeal centrifugal leukocytapheresis; Immune modulation; Inflammation; Sepsis
1.544
153
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,419,183
Triple blockade of Ido-1, PD-L1 and MEK as a potential therapeutic strategy in NSCLC.
Journal of translational medicine
J Transl Med
20
1
10.1186/s12967-022-03730-y
eng
2,022
11
22
2,022
11
22
[BACKGROUND] Despite the recent progress in the treatment and outcome of Non Small Cell Lung Cancer (NSCLC), immunotherapy has still significant limitations reporting a significant proportion of patients not benefiting from therapy, even in patients with high PD-L1 expression. We have previously demonstrated that the c...
Checkpoint inhibitor; EMT; Ido-1; Resistance
1.544
153
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,419,178
Are all types of empathy associated with lower aggression in athletes? A cross-sectional study on Iranian athletes.
BMC psychology
BMC Psychol
10
1
10.1186/s40359-022-00985-4
eng
2,022
11
22
2,022
11
22
[BACKGROUND] This study aimed to evaluate the association between cognitive and affective empathy and aggression in a sample of Iranian athletes. [METHODS] We designed a cross-sectional study. The participants were selected by multistage random sampling among six colleges in Tehran, Iran's capital. We used the interper...
Aggression; Athletes; Empathy; Sports
0.906
49
Medicine; Psychology
Medicine; Psychology
2,022
36,419,171
The role of bone marrow on the mechanical properties of trabecular bone: a systematic review.
Biomedical engineering online
Biomed Eng Online
21
1
10.1186/s12938-022-01051-1
eng
2,022
11
23
2,022
11
23
[BACKGROUND] Accurate evaluation of the mechanical properties of trabecular bone is important, in which the internal bone marrow plays an important role. The aim of this systematic review is to investigate the roles of bone marrow on the mechanical properties of trabecular bone to better support clinical work and labor...
Bone; Bone marrow; Mechanical properties; Mechanical testing; Trabecular bone
0.663
102
Biomaterials; Biomedical Engineering; Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Engineering; Health Professions; Materials Science; Medicine
2,022
36,419,133
Effect of cup, syringe, and finger feeding on time of oral feeding of preterm neonate's: a randomized controlled clinical trial.
Journal of health, population, and nutrition
J Health Popul Nutr
41
1
10.1186/s41043-022-00336-4
eng
2,022
11
22
2,022
11
22
[BACKGROUND] The oral nutrition is big challenge for preterm neonates. Since the best oral feeding method for preterm neonates is not yet known, the present study aimed to evaluate the effect of cup, syringe, and finger feeding methods on reaching the time of full oral feeding and weight gain among preterm neonates. [M...
Cup feeding; Finger feeding; Full oral feeding; Methods of oral nutrition of preterm neonate; Syringe feeding
0.549
79
Food Science; Public Health, Environmental and Occupational Health; Health, Toxicology and Mutagenesis
Agricultural and Biological Sciences; Environmental Science; Medicine
2,022
36,419,113
The relationship of parenting style and eating behavior in preschool children.
BMC psychology
BMC Psychol
10
1
10.1186/s40359-022-00981-8
eng
2,022
11
22
2,022
11
22
[BACKGROUND] Eating behavior represents individual appetitive traits which are related to the individual's regulation of food intake. Eating behavior develops at an early age. There is some evidence that parenting styles might impact on the child's eating behavior. The aim of this study was to investigate the relations...
Eating behavior; Parenting style; Preschool; SPLASHY
0.906
49
Medicine; Psychology
Medicine; Psychology
2,022
36,419,002
International Delphi-based consensus on the appropriate use and effect of Benzydamine hydrochloride in the treatment of sore throat.
BMC primary care
BMC Prim Care
23
1
10.1186/s12875-022-01901-w
eng
2,022
11
23
2,022
11
23
[BACKGROUND] Benzydamine hydrochloride is a locally-acting Non-Steroidal Anti-Inflammatory Drug (NSAID) with combined local anesthetic and analgesic properties, indicated for the symptomatic relief of pain in acute sore throat. The aim of this study was to obtain an European Consensus among pharmacists, general practit...
Benzydamine; Delphi-based consensus; General practitioner; Oropharynx; Pharmacists; Sore throat; Symptomatic treatment of acute sore throat
0.981
95
Family Practice; Medicine
Medicine
2,022
36,418,938
A primary cardiac schwannoma of the right ventricle: a case report and literature review.
BMC cardiovascular disorders
BMC Cardiovasc Disord
22
1
10.1186/s12872-022-02941-x
eng
2,022
11
22
2,022
11
22
[BACKGROUND] Primary cardiac schwannoma remains extremely rare and difficult to distinguish from other myocardial tumours. We report a case of cardiac schwannoma that occurred in the lateral wall of the right ventricle and grew in the myocardial walls. It is the third case of schwannoma that occurred in the free wall o...
Cardiac tumour; Case report; Schwannoma
0.601
76
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,418,785
Excess costs of multiple sclerosis: a register-based study in Sweden.
The European journal of health economics : HEPAC : health economics in prevention and care
Eur J Health Econ
24
8
10.1007/s10198-022-01547-6
eng
2,023
11
null
2,022
11
23
[BACKGROUND AND OBJECTIVE] Population-based estimates of the socioeconomic burden of multiple sclerosis (MS) are limited, especially regarding primary healthcare. This study aimed to estimate the excess costs of people with MS that could be attributed to their MS, including primary healthcare. [METHODS] An observationa...
Cost of illness; Disability pension; Healthcare costs; Medical/health economics; Multiple sclerosis; Primary healthcare; Productivity losses; Propensity score matching; Real world data; Sick leave
1.08
71
Economics, Econometrics and Finance; Health Policy
Economics, Econometrics and Finance; Medicine
2,023
36,418,485
Congenital diaphragmatic hernia: phosphodiesterase-5 and Arginase inhibitors prevent pulmonary vascular hypoplasia in rat lungs.
Pediatric research
Pediatr Res
95
4
10.1038/s41390-022-02366-4
eng
2,024
3
null
2,022
11
23
[BACKGROUND] Severe pulmonary hypoplasia related to congenital diaphragmatic hernia (CDH) continues to be a potentially fatal condition despite advanced postnatal management strategies. [OBJECTIVE] To evaluate the effect of the antenatal sildenafil and 2(S)-amino-6-boronohexanoic acid (ABH-Arginase inhibitor) on lung v...
null
1.171
176
Pediatrics, Perinatology and Child Health
Medicine
2,024
36,418,161
Effects of admission systemic inflammatory indicators on clinical outcomes in patients with vertebrobasilar artery occlusion: insight from the PERSIST registry.
Journal of neurointerventional surgery
J Neurointerv Surg
15
e2
10.1136/jnis-2022-019437
eng
2,023
11
null
2,022
11
23
[BACKGROUND] Few studies have focused on the effect of systemic inflammation in vertebrobasilar artery occlusion (VBAO). The aim of this study was to investigate the relationship between inflammatory indicators and the prognosis of VBAO patients receiving endovascular treatment (EVT). [METHOD] Patients with VBAO who we...
Artery; Inflammation; Inflammatory Response; Intervention; Stroke
1.659
90
Medicine; Neurology; Surgery
Medicine
2,023
36,418,122
Prevalence of skin pressure injury in critical care patients in the UK: results of a single-day point prevalence evaluation in adult critically ill patients.
BMJ open
BMJ Open
12
11
10.1136/bmjopen-2021-057010
eng
2,022
11
23
2,022
11
23
[OBJECTIVES] Hospital-acquired pressure injuries (PIs) are a source of morbidity and mortality, and many are potentially preventable. [DESIGN] This study prospectively evaluated the prevalence and the associated factors of PIs in adult critical care patients admitted to intensive care units (ICU) in the UK. [SETTING] T...
AUDIT; Adult anaesthesia; Adult intensive critical care; PREVENTIVE MEDICINE
1.059
176
Medicine
Medicine
2,022
36,418,116
Perspectives on the COVID-19 vaccine uptake: a qualitative study of community members and health workers in Zambia.
BMJ open
BMJ Open
12
11
10.1136/bmjopen-2021-058028
eng
2,022
11
23
2,022
11
23
[OBJECTIVE] Since introduction of the programme in April 2021, COVID-19 vaccine uptake has been low at less than 20%. This study explored community members' and health workers' perspectives on the COVID-19 vaccine uptake and its influencing factors in Zambia. [STUDY DESIGN] A qualitative study employing focus group dis...
COVID-19; primary care; public health; qualitative research
1.059
176
Medicine
Medicine
2,022
36,417,398
Prevalence and characteristics of family history of sudden unexplained death and predictors of negative attitude of family members toward medical autopsy and family screening in Saudi Arabia: A cross-sectional study.
PloS one
PLoS One
17
11
10.1371/journal.pone.0277914
eng
2,022
null
null
2,022
11
23
[INTRODUCTION] Little is known about sudden unexplained death (SUD) in Saudi Arabia. Moreover, family screening and medical autopsy are not routinely performed due to perceived religious and cultural resistance. However, this has never been systematically examined. We sought to describe the prevalence and characteristi...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,417,266
Substance Use Descriptive Norms and Behaviors among US College Students: Findings from the Healthy Minds Study.
Epidemiologia (Basel, Switzerland)
Epidemiologia (Basel)
3
1
10.3390/epidemiologia3010005
eng
2,022
1
27
2,022
1
27
[BACKGROUND] Social norms have been associated with alcohol use in college populations; however, more research is needed to confirm the associations between social norms and a range of substance use behaviors during the COVID-19 pandemic. [METHODS] We analyzed data from the Healthy Minds Study (September 2020-December ...
alcohol; cannabis; norms; tobacco; vaping
null
14
Epidemiology; Medicine
Medicine
2,022
36,417,019
Ruptured pulmonary artery pseudoaneurysm treated with stent graft: case report and literature review.
CVIR endovascular
CVIR Endovasc
5
1
10.1186/s42155-022-00339-6
eng
2,022
11
22
2,022
11
22
[BACKGROUND] Hemoptysis is a severe condition, associated with a high mortality rate from asphyxiation. Less than 5% of cases come from the pulmonary arterial circulation and large pseudoaneurysm are rarely treatable by stent graft. [CASE PRESENTATION] We present the case of a 74-year-old man who suffered from a new on...
Aneurysm false; Embolization; Hemoptysis; Pulmonary artery; Stent
null
null
null
null
null
36,416,904
Reproducibility of MRI-derived liver surface nodularity score: analysis of patients with repeated MRI in various scanners.
Abdominal radiology (New York)
Abdom Radiol (NY)
48
2
10.1007/s00261-022-03744-6
eng
2,023
2
null
2,022
11
23
[PURPOSE] To assess trans-regional differences, reproducibility across different MRI scanners, and interobserver agreement of liver surface nodularity (LSN) score from routine liver MRI and to evaluate the correlation between LSN score and liver stiffness (LS) value on MR elastography. [MATERIALS AND METHODS] Ninety pa...
Fibrosis; Liver cirrhosis; Magnetic resonance imaging; Reproducibility
0.78
91
Urology; Gastroenterology; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine
2,023
36,416,603
Interplay Between the In-Vitro Cleaning Performance and Wear of Manual Toothbrushes.
Oral health preventive dentistry
Oral Health Prev Dent
20
null
10.3290/j.ohpd.b3601687
eng
2,022
11
23
2,022
11
23
[PURPOSE] This in-vitro study deals with the question of whether the wear and tear of the manual toothbrush over a simulated timeframe up to 24 months has an effect on its cleaning performance. The purpose was to find indications as to whether and when a toothbrush needs to be replaced based on its cleaning performance...
cleaning; performance; toothbrush; wear and tear
null
null
null
null
null
36,416,492
Exploratory investigation of a patient-informed low-dose psilocybin pulse regimen in the suppression of cluster headache: Results from a randomized, double-blind, placebo-controlled trial.
Headache
Headache
62
10
10.1111/head.14420
eng
2,022
11
null
2,022
11
23
[OBJECTIVE] Using a patient-informed regimen, we conducted an exploratory randomized, double-blind, placebo-controlled study to systematically investigate the effects of psilocybin in cluster headache. [BACKGROUND] Sustained reductions in cluster headache burden after limited quantities of psilocybin-containing mushroo...
cluster headache; headache; preventive treatment; psilocybin; psychedelics; transitional treatment
1.283
146
Neurology; Neurology
Medicine; Neuroscience
2,022
36,416,309
The Caged Knickerbocker: A Novel Modification to Targeted False Lumen Management in Complex Aortic Dissection.
Vascular and endovascular surgery
Vasc Endovascular Surg
57
3
10.1177/15385744221141228
eng
2,023
4
null
2,022
11
23
[INTRODUCTION] Targeted false lumen management has been described for complex presentations of aortic dissection. The "Knickerbocker" technique is often referenced and includes dilating a focal portion of an oversized endograft in the true lumen to purposefully rupture the false lumen septum, but at the expense of incr...
false lumen; knickerbocker; thoracic endovascular repair; type B aortic dissection
0.348
56
Cardiology and Cardiovascular Medicine; Medicine; Surgery
Medicine
2,023
36,416,282
α-Synuclein aggregation causes muscle atrophy through neuromuscular junction degeneration.
Journal of cachexia, sarcopenia and muscle
J Cachexia Sarcopenia Muscle
14
1
10.1002/jcsm.13123
eng
2,023
2
null
2,022
11
23
[BACKGROUND] Sarcopenia is common in patients with Parkinson's disease (PD), showing mitochondrial oxidative stress in skeletal muscle. The aggregation of α-synuclein (α-Syn) to induce oxidative stress is a key pathogenic process of PD; nevertheless, we know little about its potential role in regulating peripheral nerv...
Area; Muscle atrophy; Neuromuscular junction; Oxidative stress; Parkinson's disease
2.816
112
Orthopedics and Sports Medicine; Physiology
Medicine
2,023
36,416,254
Rate of atypical nodal metastases in surgically treated HPV-associated oropharyngeal squamous cell carcinoma.
Head neck
Head Neck
45
2
10.1002/hed.27256
eng
2,023
2
null
2,022
11
23
[BACKGROUND] Understanding of nodal metastasis in patients with HPV+ oropharyngeal squamous cell carcinoma (OPSCC) is warranted. [METHODS] Patients with HPV+ OPSCC who underwent neck dissection (ND) between 2016 and 2021 were reviewed. Pathology reports were reviewed for lymph node (LN) metastases. Noncontiguous metast...
HPV; neck dissection; nodal metastasis; oropharyngeal squamous cell carcinoma
null
null
null
null
null
36,416,196
Global burden of disease attributable to high systolic blood pressure in older adults, 1990-2019: an analysis for the Global Burden of Disease Study 2019.
European journal of preventive cardiology
Eur J Prev Cardiol
30
10
10.1093/eurjpc/zwac273
eng
2,023
8
1
null
null
null
[AIMS] High systolic blood pressure (HSBP), a significant public health challenge, has not been systematically studied in the elderly population in the context of global aging. Understanding the temporal trends of the disease burden associated with HSBP in the elderly population is essential to control and mitigate the...
Disease burden; High systolic blood pressure; Old adult
1.866
130
Cardiology and Cardiovascular Medicine; Epidemiology
Medicine
2,023
36,416,053
Operative treatment in non-emergency sports injuries: a sports medicine clinic experience.
The Physician and sportsmedicine
Phys Sportsmed
51
6
10.1080/00913847.2022.2151325
eng
2,023
12
null
2,022
11
28
[PURPOSE] To elucidate referrals from sports medicine clinic (SMC) to orthopedics, consensus rates among physicians and surgeons on surgical need in these patients, and reasoning of the patients who refused to have surgery despite the recommendations by both groups in non-emergency sports injury patients. [METHODS] We ...
Sports injuries; injury epidemiology; referral rates; surgical treatment
0.804
58
Physical Therapy, Sports Therapy and Rehabilitation; Orthopedics and Sports Medicine; Sports Science
Health Professions; Medicine
2,023
36,415,998
Replacing sedentary time with light activity was associated with less adiposity across several depots in African ancestry men.
Obesity (Silver Spring, Md.)
Obesity (Silver Spring)
30
12
10.1002/oby.23582
eng
2,022
12
null
null
null
null
[OBJECTIVE] The aim of this study was to determine whether displacement of sedentary time with activity was cross-sectionally associated with less adiposity among Black Caribbean men in the Tobago Health Study. [METHODS] Objectively assessed activity was categorized as sedentary ( 1.5 metabolic equivalents; METs), ligh...
null
1.826
234
Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine; Nutrition and Dietetics
Biochemistry, Genetics and Molecular Biology; Medicine; Nursing
2,022
36,415,964
Racial disparities among older adults with acute myocardial infarction: The SILVER-AMI study.
Journal of the American Geriatrics Society
J Am Geriatr Soc
71
2
10.1111/jgs.18084
eng
2,023
2
null
2,022
11
23
[BACKGROUND] Despite an aging population, little is known about racial disparities in aging-specific functional impairments and mortality among older adults hospitalized for acute myocardial infarction (AMI). [METHODS] We analyzed data from patients aged 75 years or older who were hospitalized for AMI at 94 US hospital...
Black/African American; acute myocardial infarction; functional impairment; health care disparities; race
1.872
273
Geriatrics and Gerontology
Medicine
2,023
36,415,800
Application of Different Continuous Renal Replacement Therapy Hemofilter in Patients with Septic Shock Complicated with Acute Renal Injury.
Iranian journal of public health
Iran J Public Health
51
10
10.18502/ijph.v51i10.10990
eng
2,022
10
null
null
null
null
[BACKGROUND] We aimed to compare the clinical effects of continuous renal replacement therapy (CRRT) with different hemofilters in patients with septic shock and acute kidney injury (AKI). [METHODS] Thirty patients with septic shock complicated with AKI admitted to The Fourth Affiliated Hospital of Anhui Medical Univer...
Acute kidney injury; Continuous renal replacement therapy; Septic shock
0.358
60
Public Health, Environmental and Occupational Health
Medicine
2,022
36,415,772
Chlorpromazine as Treatment for Refractory Agitation Associated with Pediatric Delirium.
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
J Pediatr Pharmacol Ther
27
8
10.5863/1551-6776-27.8.725
eng
2,022
null
null
2,022
11
17
[OBJECTIVE] Delirium and agitation can be devastating and prolong the length of hospitalization. As part of our continuous improvement efforts, we implemented the use of intermittent chlorpromazine therapy to target refractory agitation associated with hyperactive or mixed delirium (RAA-D). The purpose of this study wa...
antipsychotic; chlorpromazine; critical illness; delirium; pediatric
null
null
null
null
null
36,472,114
Comparison of the Pathogenicity of SARS-CoV-2 Delta and Omicron Variants by Analyzing the Expression Patterns of Immune Response Genes in K18-hACE2 Transgenic Mice.
Frontiers in bioscience (Landmark edition)
Front Biosci (Landmark Ed)
27
11
10.31083/j.fbl2711316
eng
2,022
11
30
null
null
null
[BACKGROUND] The recently emerged variants of the severe acute respiratory coronavirus 2 (SARS-CoV-2) pose a threat to public health. Understanding the pathogenicity of these variants is a salient factor in the development of effective SARS-CoV-2 therapeutics. This study aimed to compare the expression patterns of gene...
Delta; Omicron; SARS-CoV-2; apoptosis; cytokines; viral pathogenicity
null
null
null
null
null
36,471,638
The effect of the endoscopic device Endocuff™/Endocuff vision™ on quality standards in colonoscopy: A systematic review and meta-analysis of randomized trials.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Colorectal Dis
25
4
10.1111/codi.16444
eng
2,023
4
null
2,022
12
28
[AIM] The adenoma detection rate (ADR) is an important quality measure, with a high ADR reflecting high-quality colonoscopy. This systematic review and meta-analysis aimed to assess the effects of Endocuff™/Endocuff Vision™-assisted colonoscopy (EAC) versus standard colonoscopy (SC) on ADR and other clinical, patient a...
ADR; Endocuff; Endocuff vision; adenoma; colonoscopy
1.164
110
Gastroenterology
Medicine
2,023
36,471,636
Application of computer-assisted surgery in pediatric mediastinal tumor surgery.
The international journal of medical robotics + computer assisted surgery : MRCAS
Int J Med Robot
19
2
10.1002/rcs.2489
eng
2,023
4
null
2,022
12
11
[BACKGROUND] Computer-assisted Surgery system (CAS) is an effective medical imaging simulation tool, which is widely used in preoperative planning of surgery. The objective of this study is to investigate the clinical application of CAS in pediatric mediastinal tumor resection. [METHODS] This retrospective study invest...
3D reconstruction; children; computer-assisted surgery; mediastinal tumors; precision surgery
null
null
null
null
null
36,471,446
Identification and validation of an E2F-related gene signature for predicting recurrence-free survival in human prostate cancer.
Cancer cell international
Cancer Cell Int
22
1
10.1186/s12935-022-02791-9
eng
2,022
12
5
2,022
12
5
[BACKGROUND] It is well-established that biochemical recurrence is detrimental to prostate cancer (PCa). In the present study, we explored the mechanisms underlying PCa progression. [METHODS] Five cohorts from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus databases were used to perform gene set variation a...
Biochemical recurrence; E2F; GEO; Gene signature; Prostate cancer; TCGA
1.145
90
Genetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,471,350
The causal relationship between white blood cell counts and hepatocellular carcinoma: a Mendelian randomization study.
European journal of medical research
Eur J Med Res
27
1
10.1186/s40001-022-00900-y
eng
2,022
12
6
2,022
12
6
[BACKGROUND] Most of hepatocellular carcinoma (HCC) arises on the background of chronic inflammation. The presence of infiltrating inflammatory cells is associated with tumour initiation, progression and clinical response to treatment. The influence of white blood cell (WBC) subtype counts on HCC progression remains un...
Causal relationship; HCC; White blood cells
0.812
70
Medicine
Medicine
2,022
36,471,313
The pathophysiologic significance of lymphocyte subset determination in children with infectious mononucleosis, mycoplasma pneumonia and Henoch-Schönlein purpura.
BMC pediatrics
BMC Pediatr
22
1
10.1186/s12887-022-03770-9
eng
2,022
12
6
2,022
12
6
[OBJECTIVE] This study aimed to explore lymphocyte subset determinations as an aid to understanding the pathophysiology of infectious mononucleosis (IM), pneumonia due to mycoplasma infection (P-MI) and Henoch-Schönlein purpura in children. [METHODS] The peripheral blood lymphocyte subsets of 45 children with IM, 20 ch...
Cell subsets; Children; Infectious mononucleosis; Pneumonia
0.742
106
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,471,293
Childhood trauma and psychological sub-health among Chinese adolescents: the mediating effect of Internet addiction.
BMC psychiatry
BMC Psychiatry
22
1
10.1186/s12888-022-04384-2
eng
2,022
12
5
2,022
12
5
[BACKGROUND] The factors related to psychological sub-health (PSH) have been widely described, but the research on the mechanism behind the complex relationship between childhood trauma and PSH is limited. This study investigated the current situation and risk factors of PSH among Chinese adolescents. And further, expl...
Adolescents; Childhood trauma; Internet addiction; Psychological sub-health
1.291
151
Psychiatry and Mental Health
Medicine
2,022
36,471,258
Effect of different low doses of intrathecal morphine (0.1 and 0.2 mg) on pain and vital functions in patients undergoing total hip arthroplasty: a randomised controlled study.
BMC anesthesiology
BMC Anesthesiol
22
1
10.1186/s12871-022-01919-8
eng
2,022
12
5
2,022
12
5
[BACKGROUND] Orthopaedic surgeries are among the most painful procedures. By adding low-dose morphine to intrathecal bupivacaine for spinal anaesthesia, the analgesic effect can be improved. The objeсtive of the study was tо compare the efficacy and safety of lоw-dоse (0.1 mg аnd 0.2 mg) intrаtheсаl mоrphine (ITM). [ME...
Hip replacement; Multimodal analgesia; Postoperative pain; Orthopaedic surgery; Spinal morphine
0.609
58
Anesthesiology and Pain Medicine
Medicine
2,022
36,471,024
Quantifying Agglomerate-to-Wall Impaction in Dry Powder Inhalers.
Pharmaceutical research
Pharm Res
40
1
10.1007/s11095-022-03446-0
eng
2,023
1
null
2,022
12
5
[PURPOSE] The probability of agglomerate-to-wall collision was quantified using a unique image processing technique applied to high-speed microscopic images. The study aimed to investigate the effects of flow rate and particle size on the percentage of colliding agglomerates detected within an in-house powder dispersio...
dispersion mechanisms; dry powder inhalers; high-speed imaging
0.707
235
Biotechnology; Organic Chemistry; Pharmaceutical Science; Pharmacology; Pharmacology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,470,819
Educational and research needs in hypothyroidism of primary care physicians in the Community of Madrid.
Endocrinologia, diabetes y nutricion
Endocrinol Diabetes Nutr (Engl Ed)
69
10
10.1016/j.endien.2022.11.030
eng
2,022
12
null
2,022
12
2
[AIM] To document the opinion of primary care physicians on hypothyroidism and explore their educational and research needs. [METHODS] A web-based survey was released through Healthcare Management offices in Madrid to be answered anonymously by the doctors at the health centers. [RESULTS] Five hundred and forty-six out...
Education; Encuesta; Hipotiroidismo; Hypothyroidism; Primary care; Research; Survey
0.327
35
Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics; Endocrinology
Biochemistry, Genetics and Molecular Biology; Medicine; Nursing
2,022
36,470,775
Fallen angels and forgotten heroes: A descriptive qualitative study exploring the impact of the angel and hero narrative on critical care nurses.
Australian critical care : official journal of the Confederation of Australian Critical Care Nurses
Aust Crit Care
36
1
10.1016/j.aucc.2022.11.008
eng
2,023
1
null
2,022
12
2
[BACKGROUND] During the COVID-19 pandemic, the use of the labels 'heroes' and 'angels' to describe nurses (and especially critical care nurses) became prevalent. While often well intentioned, the use of these labels may not be the most positive image of nurses and the nursing profession. Critical care nurses have not p...
Covid-19; Critical care nurses; Emergency nursing; Healthcare workers; Hero narrative; Intensive care nursing; Nursing; Qualitative research; Thematic analysis
0.825
50
Critical Care Nursing; Emergency Nursing
Nursing
2,023
36,470,774
Evaluation of ferritin and the ferritin index as prognostic biomarkers in septic shock.
Australian critical care : official journal of the Confederation of Australian Critical Care Nurses
Aust Crit Care
36
5
10.1016/j.aucc.2022.10.012
eng
2,023
9
null
2,022
12
2
[BACKGROUND] Ferritin, an acute phase reactant, and the ferritin index (FI = observed ferritin level/upper limit of normal level for age and sex) may be prognostic biomarkers in septic shock and cardiac surgery patients. [OBJECTIVE] The purpose of this exploratory study is to assess the outcome associations of ferritin...
Cardiac surgery; Ferritin; Ferritin index; Hospital length of stay; ICU length of stay; Intensive care; Mortality; Septic shock
0.825
50
Critical Care Nursing; Emergency Nursing
Nursing
2,023
36,470,707
The effect of medicare and screening guidelines on colorectal cancer outcomes.
Journal of the National Medical Association
J Natl Med Assoc
115
1
10.1016/j.jnma.2022.09.006
eng
2,023
2
null
2,022
12
5
[BACKGROUND] Colorectal cancer screening has been shown effective at reducing stage at presentation, but there is differential uptake of screening based on insurance status. We sought to determine the population-level effect of Medicare and screening guidelines on colorectal screening by race and region. [METHODS] Data...
Colorectal cancer; Medicare; Racism; Screening
0.913
87
Medicine
Medicine
2,023
36,470,571
Rehabilitation of patients after CAR T-cell therapy. Experiences on 5 patients.
Transplant immunology
Transpl Immunol
76
null
10.1016/j.trim.2022.101770
eng
2,023
2
null
2,022
12
5
[OBJECTIVE] CAR T-cell therapy is an effective treatment for various relapsed or refractory haemato-oncological diseases. However, this therapy results in significant immunosuppression that lasts for months. Whether these patients are at risk during a rehabilitation stay, e.g., due to infections, has not yet been answe...
CAR T-cell therapy; Infection; Rehabilitation; Safety
0.515
68
Transplantation; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,023
36,470,462
Preterm Birth Is Associated With Adverse Cardiac Remodeling and Worse Outcomes in Patients With a Functional Single Right Ventricle.
The Journal of pediatrics
J Pediatr
255
null
10.1016/j.jpeds.2022.11.033
eng
2,023
4
null
2,022
12
5
[OBJECTIVE] To assess the effects of preterm birth on cardiac structure and function and transplant-free survival in patients with hypoplastic left heart syndrome and associated anomalies throughout the staged palliation process. [STUDY DESIGN] Data from the Single Ventricle Reconstruction trial were used to assess the...
Norwood procedure; Pediatric cardiology; cardiac remodeling; cardiac surgery; hypoplastic left heart syndrome; prematurity
1.043
246
Pediatrics, Perinatology and Child Health
Medicine
2,023
36,470,340
Biology, bionomics and life-table studies of Anopheles stephensi (Diptera: Culicidae) in Sri Lanka and estimating the vectorial potential using mathematical approximations.
Parasitology international
Parasitol Int
93
null
10.1016/j.parint.2022.102715
eng
2,023
4
null
2,022
12
2
[BACKGROUND] Anopheles stephensi is an invasive mosquito in Sri Lanka that can potentially transmit malaria. The transmission intensity is linked with biology, bionomic and behavioral aspects of a vector that are associated with the Vectorial Capacity (VC). However, the influence of larval conditions eventually affects...
An. stephensi; Bionomics; Life-table; Vectorial capacity
null
null
null
null
null
36,470,212
The Optimization of Guideline-Directed Medical Therapy during Hospitalization among Patients with Heart Failure with Reduced Ejection Fraction in Daily Clinical Practice.
Cardiology
Cardiology
148
1
10.1159/000528505
eng
2,023
null
null
2,022
12
5
[INTRODUCTION] Hospitalization due to heart failure (HF) progression is associated with poor prognosis. This highlights the role of the implementation of guideline-directed medical therapy (GDMT) in improving the morbidity and mortality of patients with heart failure with reduced ejection fraction (HFrEF). There are li...
Guideline-directed medical therapy; Heart failure; Heart failure with reduced ejection fraction; Pharmacotherapy; Worsening heart failure
0.547
77
Cardiology and Cardiovascular Medicine; Pharmacology
Medicine
2,023
36,469,993
Establishment of CT diagnostic reference levels (DRLs) for a Singapore healthcare cluster.
Radiography (London, England : 1995)
Radiography (Lond)
29
1
10.1016/j.radi.2022.11.002
eng
2,023
1
null
2,022
12
5
[INTRODUCTION] The use of computed tomography (CT) in healthcare institutions has increased rapidly in recent years. The Singapore Health Services (SingHealth) cluster of healthcare institutions has taken the first step in establishing a local cluster-wide CT Diagnostic Reference Levels (DRL) in Singapore. CT dose data...
Computed tomography; Diagnostic imaging; Diagnostic reference levels; Dose optimisation; Patient safety; Radiation dose
0.68
43
Assessment and Diagnosis; Research and Theory; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine; Nursing
2,023
36,469,668
Optic nerve involvement in CACNA1F-related disease: observations from a multicentric case series.
Ophthalmic genetics
Ophthalmic Genet
44
2
10.1080/13816810.2022.2132514
eng
2,023
4
null
2,022
12
5
[BACKGROUND] Congenital Stationary Night Blindness (CSNB) constitutes a group of non-progressive retinal disorders characterized by disturbances in scotopic vision and/or by a delay in adaptation to darkness, as well as by low visual acuity, myopia, nystagmus, and strabismus. Color vision and fundus appearance tend to ...
CACNA1F gene; congenital stationary night blindness; ganglion cell loss; myopia; optic neuropathy
0.509
47
Ophthalmology; Pediatrics, Perinatology and Child Health; Genetics
Medicine
2,023
36,469,284
Racial/Ethnic Differences in Sexually Transmitted Infection Testing Among Transgender Men and Nonbinary Assigned Female at Birth Young Adults in the United States: a National Study.
Journal of racial and ethnic health disparities
J Racial Ethn Health Disparities
10
6
10.1007/s40615-022-01467-4
eng
2,023
12
null
2,022
12
5
[BACKGROUND] Sexually transmitted infections (STIs) cause a major burden of disease in the United States (US)-especially among structurally marginalized populations, including transgender and nonbinary people, individuals assigned female at birth (AFAB), Black and Latinx/e individuals, and young adults. Although screen...
Health disparities; Race/ethnicity; Racism; Sexually transmitted infection testing; Transgender health
1.55
56
Anthropology; Health Policy; Health; Public Health, Environmental and Occupational Health; Sociology and Political Science
Medicine; Social Sciences
2,023
36,468,401
Influence of insurance status on the postoperative outcomes of cytoreductive surgery and HIPEC.
Journal of surgical oncology
J Surg Oncol
127
4
10.1002/jso.27147
eng
2,023
3
null
2,022
12
5
[BACKGROUND] Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is increasingly performed for peritoneal surface malignancies but remains associated with significant morbidity. Scant research is available regarding the impact of insurance status on postoperative outcomes. [METHODS] Patients...
HIPEC; appendiceal cancer; disparities; medicaid; medicare; peritoneal surface malignancies
0.81
136
Surgery; Medicine; Oncology
Medicine
2,023
36,468,242
Identification of proline, 1-pyrroline-5-carboxylate and glutamic acid as biomarkers of depression reflecting brain metabolism using carboxylomics, a new metabolomics method.
Psychiatry and clinical neurosciences
Psychiatry Clin Neurosci
77
4
10.1111/pcn.13517
eng
2,023
4
null
2,022
12
22
[AIM] Depression is a psychiatric disease which is accompanied by metabolic disorder. Though depression has been widely studied, its metabolism is yet to be illustrated. We aimed to manifest the underlying mechanisms to diagnose depression. [METHODS] One hundred thirty serum samples, including 65 patients and 65 health...
SPCSDCarboxyl; biomarker identification; co-occurrence analysis; depression; iPath
1.25
96
Medicine; Neurology; Neurology; Neuroscience; Psychiatry and Mental Health
Medicine; Neuroscience
2,023
36,468,117
Investigation of the relationship between contact lens design parameters and refractive changes in Ortho-K.
Heliyon
Heliyon
8
11
10.1016/j.heliyon.2022.e11699
eng
2,022
11
null
2,022
11
19
[PURPOSE] To investigate the relationship between Ortho-K contact lens design parameters and refractive power change of the eye through a parametric mathematical representation. [METHODS] The current study utilises fully anonymized records of 249 eyes, 132 right eyes, and 117 left eyes from subjects aged 14.1 ± 4.0 yea...
Contact lenses; Cornea; Eye; Ortho-K; Target power change
0.609
115
Multidisciplinary
Multidisciplinary
2,022
36,468,062
Segmentation and differentiation of periventricular and deep white matter hyperintensities in 2D T2-FLAIR MRI based on a cascade U-net.
Frontiers in neurology
Front Neurol
13
null
10.3389/fneur.2022.1021477
eng
2,022
null
null
2,022
11
17
[BACKGROUND] White matter hyperintensities (WMHs) are a subtype of cerebral small vessel disease and can be divided into periventricular WMHs (pvWMHs) and deep WMHs (dWMHs). pvWMHs and dWMHs were proved to be determined by different etiologies. This study aimed to develop a 2D Cascade U-net (Cascade U) for the segmenta...
2D T2-FLAIR; cascade U-net; deep white matter hyperintensities; image segmentation; periventricular white matter hyperintensities
0.978
118
Neurology; Neurology
Medicine; Neuroscience
2,022
36,467,505
Development and Validation of a Combined Ferroptosis and Immune Prognostic Model for Melanoma.
Journal of oncology
J Oncol
2022
null
10.1155/2022/1840361
eng
2,022
null
null
2,022
11
24
[BACKGROUND] Melanoma development and progression are significantly influenced by ferroptosis and the immune microenvironment. However, there are no reliable biomarkers for melanoma prognosis prediction based on ferroptosis and immunological response. [METHODS] Ferroptosis-related genes (FRGs) were retrieved from the F...
null
null
null
null
null
null
36,467,477
Clinical characteristics and genetics of ten Chinese children with PRRT2-associated neurological diseases.
Frontiers in pediatrics
Front Pediatr
10
null
10.3389/fped.2022.997088
eng
2,022
null
null
2,022
11
17
[BACKGROUND] Proline-rich transmembrane protein 2 (PRRT2) plays an important role in the central nervous system and mutations in the gene are implicated in a variety of neurological disorders. This study aimed to summarize the clinical characteristics and gene expression analysis of neurological diseases related to the...
expression; nervous system-related diseases; proline-rich transmembrane protein 2 (PRRT2); synaptosome-associated protein 25 (SNAP 25); whole-exome genome sequencing
0.798
83
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,467,462
Growth Hormone Response to L-Arginine Alone and Combined with Different Doses of Growth Hormone-Releasing Hormone: A Systematic Review and Meta-Analysis.
International journal of endocrinology
Int J Endocrinol
2022
null
10.1155/2022/8739289
eng
2,022
null
null
2,022
11
23
[BACKGROUND] Arginine (ARG) can modulate growth hormone (GH) release by suppressing its endogenous inhibitory regulator, somatostatin. ARG also induces the release of the GH-releasing hormone (GHRH). This study aims to review the effects of L-arginine supplementation alone and combined with GHRH in different doses on G...
null
null
null
null
null
null
36,467,307
Proprioceptive Neuromuscular Facilitation Neck Pattern and Trunk Specific Exercise on Trunk Control and Balance-an Experimental Study.
International journal of therapeutic massage bodywork
Int J Ther Massage Bodywork
15
4
10.3822/ijtmb.v15i4.727
eng
2,022
12
null
2,022
12
1
[BACKGROUND] Most stroke survivors continue to live with disabilities and may require physical rehabilitation to control the trunk and balance during the post-stroke period. The cause of lack of trunk control and balance among stroke patients is the weakened trunk muscle strength. [PURPOSE] To study the effect of propr...
balance; neck pattern; proprioceptive neuromuscular facilitation; stroke; trunk control; trunk-specific exercise
null
null
null
null
null
36,467,120
A case of herpes zoster ophthalmicus with optic neuritis of the total length of the optic nerve in the orbital space and ischemic optic neuropathy.
American journal of ophthalmology case reports
Am J Ophthalmol Case Rep
28
null
10.1016/j.ajoc.2022.101756
eng
2,022
12
null
2,022
11
23
[PURPOSE] We herein report a case of optic neuritis and ischemic optic neuropathy associated with herpes zoster ophthalmicus and decreased visual acuity. [OBSERVATIONS] A 65-year-old man with no special medical history had a headache on the right side in December 2019, and a few days later, a facial rash appeared on th...
Herpes zoster ophthalmicus; Ischemic optic neuropathy; Optic neuritis; Varicella-zoster virus (VZV)
null
null
null
null
null
36,466,710
Analysis of Cytokine Levels in Meibum and Clinical Correlations with Meibomian Gland Dysfunction.
Disease markers
Dis Markers
2022
null
10.1155/2022/4259067
eng
2,022
null
null
2,022
11
23
[OBJECTIVES] This study is aimed at investigating the difference of meibum chemokines in MGD subjects with different degrees of MGD and the correlations of meibum chemokines with ocular surface parameters. [METHODS] Twenty MGD subjects (MQ score 8) and twenty MGD subjects (MQ score ≤ 8) were enrolled to examine ocular...
null
0.662
85
Biochemistry; Clinical Biochemistry; Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,466,554
Research of the Active Components and Potential Mechanisms of Qingfei Gujin Decoction in the Treatment of Osteosarcoma Based on Network Pharmacology and Molecular Docking Technology.
Computational and mathematical methods in medicine
Comput Math Methods Med
2022
null
10.1155/2022/7994425
eng
2,022
null
null
2,022
11
23
[AIM] Qingfei Gujin Decoction (QGD) has been shown to be effective against osteosarcoma. This research was aimed at investigating the main active ingredients and potential mechanisms of QGD acting on osteosarcoma through network pharmacology and molecular docking techniques. [METHODS] The active ingredients and targets...
null
null
null
null
null
null
36,466,493
Comparison of craniofacial morphology in individuals with and without hypodontia with a special focus on the number of congenitally missing teeth.
Frontiers in public health
Front Public Health
10
null
10.3389/fpubh.2022.1013862
eng
2,022
null
null
2,022
11
18
[BACKGROUND] Hypodontia might negatively affect dental function and esthetics, what might affect patients' self-esteem, communication behavior, professional performance and thus quality of life. The aim of this study was to estimate the influence of number of congenital missing teeth on dentofacial features. [METHODS] ...
congenital anomalies; craniofacial morphology; esthetics; hypodontia; lateral cephalography
1.125
119
Public Health, Environmental and Occupational Health
Medicine
2,022
36,465,902
Innovative approaches to service integration addressing the unmet needs of irritable bowel syndrome patients and new approaches for the needs of IBS patients.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.998838
eng
2,022
null
null
2,022
11
16
[BACKGROUND] Irritable bowel syndrome (IBS) is a common multifactorial condition that affects the large intestine and is characterized by chronic and relapsing abdominal pain and altered bowel habit. IBS is due to a combination of genetic, environmental and dietary factors. It's usually a lifelong problem very frustrat...
digital health; irritable bowel syndrome; mHealth; nutrition; physical activity
0.926
102
Medicine
Medicine
2,022
36,465,807
Mortality-Related Risk Factors and Novel Antimicrobial Regimens for Carbapenem-Resistant Enterobacteriaceae Infections: A Systematic Review.
Infection and drug resistance
Infect Drug Resist
15
null
10.2147/IDR.S390635
eng
2,022
null
null
2,022
11
28
[OBJECTIVE] Carbapenem-resistant Enterobacteriaceae (CRE) has become a significant public health problem in the last decade. We aimed to explore the risk factors of mortality in patients with CRE infections and to focus on the current evidence on antimicrobial regimens for CRE infections, particularly from the perspect...
CRE; antimicrobial; carbapenem resistant Enterobacteriaceae; mortality; risk factors; treatment
0.84
74
Infectious Diseases; Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,022
36,465,613
Predictive ability of obesity- and lipid-related indicators for metabolic syndrome in relatively healthy Chinese adults.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
13
null
10.3389/fendo.2022.1016581
eng
2,022
null
null
2,022
11
18
[BACKGROUND AND OBJECTIVE] Metabolic syndrome (MetS) is an important risk factor for cardiovascular complications and kidney damage. Obesity- and lipid-related indices are closely related to MetS, and different indices have different predictive abilities for MetS. This study aimed to evaluate the predictive value of ei...
adults; healthy; lipid; lipid accumulation product; metabolic syndrome; obesity
1.278
138
Endocrinology, Diabetes and Metabolism
Medicine
2,022
36,465,611
The association between body mass index and risk of preoperative oxygenation impairment in patients with the acute aortic syndrome.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
13
null
10.3389/fendo.2022.1018369
eng
2,022
null
null
2,022
11
17
[OBJECTIVE] The study aimed to determine the relationship between body mass index (BMI) and the risk of acute aortic syndrome (AAS) with preoperative oxygenation impairment. [METHODS] A meta-analysis of published observational studies involving BMI and AAS with preoperative oxygenation impairment was conducted. A total...
acute aortic syndrome; body mass index; obesity; overweight; preoperative oxygenation impairment
1.278
138
Endocrinology, Diabetes and Metabolism
Medicine
2,022
36,465,321
Low-energy Pulsed Electromagnetic Field Therapy Reduces Pain in Fibromyalgia: A Randomized Single-blind Controlled Pilot Study.
Rheumatology and immunology research
Rheumatol Immunol Res
3
2
10.2478/rir-2022-0013
eng
2,022
6
null
2,022
7
6
[OBJECTIVES] Fibromyalgia symptoms have a significant impact on the quality of life and respond poorly to medications. It has been hypothesized that the use of low-energy pulsed electromagnetic field (PEMF) induces neuroprotective effects that may interfere with pain perception. We explored the efficacy of PEMF in pati...
diffuse pain syndrome; fatigue; quality of life; widespread pain
null
null
null
null
null
36,465,307
Screen time and adolescents' mental health before and after the COVID-19 lockdown in Switzerland: A natural experiment.
Frontiers in psychiatry
Front Psychiatry
13
null
10.3389/fpsyt.2022.981881
eng
2,022
null
null
2,022
11
16
[BACKGROUND] During the COVID-19 lockdown in 2020, adolescents' mental health was largely undermined. A general increment in screen time was reported. However, the long-term effects of the latter on adolescents' mental health are still little explored. [METHODS] In the present natural experiment, we investigated these ...
COVID-19; adolescents; lockdown; longitudinal; mental health; natural experiment; screen time; social media
1.222
134
Psychiatry and Mental Health
Medicine
2,022
36,465,288
Neural activity in adults with major depressive disorder differs from that in healthy individuals: A resting-state functional magnetic resonance imaging study.
Frontiers in psychiatry
Front Psychiatry
13
null
10.3389/fpsyt.2022.1028518
eng
2,022
null
null
2,022
11
17
[OBJECTIVE] Currently, findings regarding resting-state functional magnetic resonance imaging studies of major depressive disorder (MDD) are inconsistent. In contrast to the previously used a priori seed-based functional connectivity analyses, this study employed whole-brain exploratory analyses and aimed to explore ne...
MRI; brain; functional connectivity; major depressive disorder; resting-state
1.222
134
Psychiatry and Mental Health
Medicine
2,022
36,465,208
Comparison of the Effects of Acute Appendicitis and Chronic Cholecystitis on Intestinal Mucosal Function During Surgery.
Cureus
Cureus
14
11
10.7759/cureus.30953
eng
2,022
11
null
2,022
11
1
[OBJECTIVE] The objective of this study is to explore the effect of acute appendicitis and chronic cholecystitis on inflammatory factors and intestinal mucosal function during operation. [METHODS] This was a prospective cohort study. Forty-four patients including those who underwent elective cholecystectomy (Group A, n...
acute appendicitis; chronic cholecystitis; inflammatory factors; intestinal mucosal function; intestinal permeability
null
null
null
null
null
36,464,979
Preoperative health-related quality of life is independently associated with postoperative mortality risk following total hip or knee arthroplasty : seven to eight years' follow-up.
Bone joint open
Bone Jt Open
3
12
10.1302/2633-1462.312.BJO-2022-0131.R1
eng
2,022
12
null
null
null
null
[AIMS] The primary aim was to assess whether preoperative health-related quality of life (HRQoL) was associated with postoperative mortality following total hip arthroplasty (THA) and knee arthroplasty (KA). Secondary aims were to assess whether patient demographics/comorbidities and/or joint-specific function were ass...
Comorbidities; Cox regression analysis; EQ-5D; arthroplasty; arthroplasty register; chronic obstructive pulmonary disease; connective tissue disease; diabetes; hip; knee; knee arthroplasty (KA); mortality; quality of life; total hip or knee arthroplasty; waiting list
null
null
null
null
null
36,464,965
Knowledge of vascular access among hemodialysis unit nurses and its influencing factors: a cross-sectional study.
Annals of palliative medicine
Ann Palliat Med
11
11
10.21037/apm-22-1204
eng
2,022
11
null
null
null
null
[BACKGROUND] Nurses in hemodialysis (HD) units are the main performers in the maintenance and management of HD patients' vascular access, and the cognition degree of their specialized knowledge of vascular access directly affects the quality of vascular access management. However, most of the investigations on the cogn...
HD unit nurses; Vascular access; influencing factors; knowledge
null
null
null
null
null
36,464,964
The efficacy and safety of an improved percutaneous peritoneal dialysis catheter placement technique in urgent-start peritoneal dialysis patients: a retrospective cohort study.
Annals of palliative medicine
Ann Palliat Med
11
11
10.21037/apm-22-1270
eng
2,022
11
null
null
null
null
[BACKGROUND] Urgent-start peritoneal dialysis has high catheterization skill requirements and that early complications. The optimal catheter placement method remains debatable in urgent-start peritoneal dialysis patients. Safe and effective peritoneal dialysis catheterization is needed in clinical work. [METHODS] We re...
Peritoneal dialysis; artificial ascites; percutaneous puncture; rectus sheath tunneling; urgent start
null
null
null
null
null
36,464,926
Teachers' motivational prosody: A pre-registered experimental test of children's reactions to tone of voice used by teachers.
The British journal of educational psychology
Br J Educ Psychol
93
2
10.1111/bjep.12567
eng
2,023
6
null
2,022
12
4
[BACKGROUND] Teachers' behaviours drive motivational climates that shape children's engagement and well-being in the classroom, but few studies examine how specific teachers' behaviours such as wording, body language, or voice contribute to these outcomes in isolation of one another. [AIMS] This pre-registered experime...
education; motivation; prosody; self-determination theory; teachers
1.738
120
Developmental and Educational Psychology; Education
Psychology; Social Sciences
2,023
36,464,851
To what extent do post-traumatic mental health and other problems reflect pre-existing problems? Findings from the prospective comparative population-based VICTIMS-study.
The International journal of social psychiatry
Int J Soc Psychiatry
69
4
10.1177/00207640221140287
eng
2,023
6
null
2,022
12
4
[BACKGROUND] Findings from prospective studies question the assumption that mental health problems observed in traumatized adults mainly reflect the effects of potentially traumatic events. [AIMS] Aim of the present comparative prospective study is to clarify the extent to which victims of potentially traumatic events ...
PTSD; anxiety; depression; financial; legal; prospective
1.649
86
Medicine; Psychiatry and Mental Health
Medicine
2,023
36,464,699
Association of bisphosphonates with diabetes risk and glycemic control: a meta-analysis.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
Osteoporos Int
34
2
10.1007/s00198-022-06616-3
eng
2,023
2
null
2,022
12
5
[UNLABELLED] Previous evidence suggests that bisphosphonates may improve glycemic control. The present meta-analysis, comprising seven studies with 1,233,844 participants, demonstrated that bisphosphonate use was significantly associated with a lower risk of diabetes. However, in the randomized controlled trial subgrou...
Bisphosphonates; Diabetes mellitus; Glycemic control; Meta-analysis; Osteoporosis
1.111
201
Endocrinology, Diabetes and Metabolism; Medicine
Medicine
2,023
36,464,653
Allograft corneal ring segment for keratoconus management: Istanbul nomogram clinical results.
European journal of ophthalmology
Eur J Ophthalmol
null
null
10.1177/11206721221142995
eng
2,022
12
4
2,022
12
4
[PURPOSE] To evaluate the clinical feasibility and visual outcomes of allograft corneal ring segment implantation for the treatment of keratoconus. [METHODS] This case series, included forty-four eyes of 32 patients with a 6-month follow-up. All cases were treated according to the Istanbul nomogram. In the Istanbul Nom...
CAIRS; KeraNatural; allograft corneal ring; intracorneal ring segment; keratoconus
0.595
69
Medicine; Ophthalmology
Medicine
2,022
36,464,571
Use of Transcutaneous Electrical Nerve Stimulation to Alleviate Thirst After Surgery: A Randomized Controlled Trial.
Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses
J Perianesth Nurs
38
2
10.1016/j.jopan.2022.07.010
eng
2,023
4
null
2,022
12
1
[PURPOSE] This prospective study investigated the preventive effect of transcutaneous electrical nerve stimulation (TENS) for postoperative thirst. [DESIGN] This experimental study was conducted with the CONSORT checklist. [METHODS] A total of 105 surgical patients who received general anesthesia were recruited from a ...
TENS; cholecystectomy; general anesthesia; oral moisture wetness; postoperative thirst
0.408
41
Medical and Surgical Nursing
Nursing
2,023
36,464,510
Using research-practice-policy partnerships to mitigate the effects of childhood trauma on educator burnout.
Child abuse neglect
Child Abuse Negl
142
Pt 1
10.1016/j.chiabu.2022.105941
eng
2,023
8
null
2,022
12
2
[BACKGROUND] The effects of COVID-19 pandemic on children have been immense. [OBJECTIVE] In this commentary, we argue for the need to utilize research-practice-policy partnerships to address the issue of educator burnout and Secondary Traumatic Stress. [PARTICIPANTS AND SETTING] Education systems have the potential to ...
Burnout; Child abuse; Research-practice-policy partnership; Secondary trauma
null
null
null
null
null
36,463,934
Brief communication: Vitamin D serum levels in American tegumentary leishmaniasis from an endemic area in Northeast Brazil.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
Braz J Infect Dis
27
1
10.1016/j.bjid.2022.102720
eng
2,023
null
null
2,022
12
2
[INTRODUCTION] The pathogenesis of cutaneous and mucosal leishmaniasis is associated with different immune responses. Vitamin D may modulate the immune system. Here we evaluate the association of vitamin D levels with the severity of the clinical forms of cutaneous and mucosal leishmaniasis. [METHODS] We conducted an o...
Cutaneous leishmaniasis; Leishmaniasis; Mucocutaneous leishmaniasis; Vitamin D
0.594
59
Infectious Diseases; Microbiology
Medicine
2,023
36,463,791
Patient safety competencies of nursing students.
Nurse education today
Nurse Educ Today
121
null
10.1016/j.nedt.2022.105666
eng
2,023
2
null
2,022
11
29
[BACKGROUND] Patient safety is an essential principle of healthcare and an indispensable element of contemporary nursing care. [OBJECTIVE] This study aims to evaluate the patient safety competencies in nursing students. [METHODS] This descriptive study was conducted with the participation of 191 nursing students, who r...
Nursing; Nursing students; Patient safety; Patient safety competencies
1.091
109
Education; Nursing
Nursing; Social Sciences
2,023
36,463,547
Pertuzumab, trastuzumab, and docetaxel for Chinese patients with previously untreated HER2-positive locally recurrent or metastatic breast cancer (PUFFIN): final analysis of a phase III, randomized, double-blind, placebo-controlled study.
Breast cancer research and treatment
Breast Cancer Res Treat
197
3
10.1007/s10549-022-06775-1
eng
2,023
2
null
2,022
12
4
[PURPOSE] PUFFIN (NCT02896855), a Chinese bridging study in patients with previously untreated HER2-positive locally recurrent or metastatic breast cancer, assessed consistency of efficacy and safety of pertuzumab plus trastuzumab and docetaxel versus placebo, trastuzumab, and docetaxel, with CLEOPATRA (NCT00567190). [...
Chinese; HER2; Locally recurrent breast cancer; Metastatic breast cancer; Pertuzumab
1.267
184
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,463,326
Gene expression associations with body mass index in the Multi-Ethnic Study of Atherosclerosis.
International journal of obesity (2005)
Int J Obes (Lond)
47
2
10.1038/s41366-022-01240-x
eng
2,023
2
null
2,022
12
3
[BACKGROUND/OBJECTIVES] Obesity, defined as excessive fat accumulation that represents a health risk, is increasing in adults and children, reaching global epidemic proportions. Body mass index (BMI) correlates with body fat and future health risk, yet differs in prediction by fat distribution, across populations and b...
null
1.504
258
Endocrinology, Diabetes and Metabolism; Medicine; Nutrition and Dietetics
Medicine; Nursing
2,023
36,463,233
TREM2 activation alleviates neural damage via Akt/CREB/BDNF signalling after traumatic brain injury in mice.
Journal of neuroinflammation
J Neuroinflammation
19
1
10.1186/s12974-022-02651-3
eng
2,022
12
3
2,022
12
3
[BACKGROUND] Neuroinflammation is one of the most important processes in secondary injury after traumatic brain injury (TBI). Triggering receptor expressed on myeloid cells 2 (TREM2) has been proven to exert neuroprotective effects in neurodegenerative diseases and stroke by modulating neuroinflammation, and promoting ...
Cognitive deficits; Neural apoptosis; Neuroinflammation; TREM2; Traumatic brain injury
2.439
168
Cellular and Molecular Neuroscience; Immunology; Neurology; Neuroscience
Immunology and Microbiology; Neuroscience
2,022
36,463,223
Culture, church, and collective: a qualitative study about gambling harm prevention and reduction in Aotearoa/New Zealand-a Tongan male perspective.
Harm reduction journal
Harm Reduct J
19
1
10.1186/s12954-022-00717-2
eng
2,022
12
3
2,022
12
3
[BACKGROUND] In New Zealand, Pacific people continue to be more at risk of gambling harm than the general population, despite increasing public health efforts and treatment service provisions introduced to address this social and health issue. In looking at why this is so, our first concern was to ask why the delivery ...
Church; Community; Cultural; Gambling; Gambling harm providers; Talanoa
1.414
71
Medicine; Psychiatry and Mental Health; Public Health, Environmental and Occupational Health
Medicine
2,022
36,462,787
New biopsy after antibiotic treatment: effect on outcomes of assisted reproduction in patients with infertility and chronic endometritis.
Reproductive biomedicine online
Reprod Biomed Online
45
6
10.1016/j.rbmo.2022.07.020
eng
2,022
12
null
2,022
8
7
[RESEARCH QUESTION] What is the effect of chronic endometritis on patients with infertility, the necessity of endometrial re-examination and the effect of improving chronic endometritis after one cycle of antibiotic treatment on pregnancy outcomes? [DESIGN] Infertile patients (n = 4003) who underwent IVF and intracytop...
Antibiotic therapy; Chronic endometritis; Endometrial biopsy; Pregnancy outcome
0.948
139
Obstetrics and Gynecology; Reproductive Medicine; Developmental Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,462,465
Comparison of five Anti-SARS-CoV-2 antibody assays across three doses of BNT162b2 reveals insufficient standardization of SARS-CoV-2 serology.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
J Clin Virol
158
null
10.1016/j.jcv.2022.105345
eng
2,023
1
null
2,022
11
25
[OBJECTIVES] To investigate the comparability of WHO standard referenced commercial SARS-CoV-2 antibody tests over three doses of BNT162b2 vaccine and up to 14 months. [METHODS] 114 subjects (without previous SARS-CoV-2 infection or immunosuppressive medication) vaccinated with three doses of BNT162b2 were included in ...
Antibody assays; SARS-CoV-2; Serology; Standardization; Vaccination
1.344
129
Infectious Diseases; Virology
Immunology and Microbiology; Medicine
2,023
36,461,842
Complication rate of overlapping versus nonoverlapping functional and stereotactic surgery: a retrospective cohort study.
Journal of neurosurgery
J Neurosurg
138
4
10.3171/2022.8.JNS212363
eng
2,023
4
1
2,022
9
30
[OBJECTIVE] Overlapping surgery, in which one attending surgeon manages two overlapping operating rooms (ORs) and is present for all the critical portions of each procedure, is an important policy that improves healthcare access for patients and case volumes for surgeons and surgical trainees. Despite several studies d...
complications; concurrent; functional neurosurgery; outcomes; overlapping surgery; stereotactic
1.173
244
Neurology; Surgery
Medicine
2,023
36,461,023
Development of an indirect ELISA using a novel linear epitope at the C-terminal region of the VP2 protein to specifically detect antibodies against Senecavirus A.
Virology journal
Virol J
19
1
10.1186/s12985-022-01934-8
eng
2,022
12
2
2,022
12
2
[BACKGROUND] Senecavirus A (SVA) is a pathogen that has recently caused porcine idiopathic vesicular disease (PIVD). The clinical signs are similar to those of foot-and-mouth disease, porcine vesicular disease, and vesicular stomatitis. Therefore, identification of SVA as a cause of PIVD is important to eliminate this ...
Diagnosis; ELISA; Epitope; Senecavirus A; VP2
1.092
104
Infectious Diseases; Virology
Immunology and Microbiology; Medicine
2,022
36,461,020
How midwives and nurses experience implementing ten steps to successful breastfeeding: a qualitative case study in an Indonesian maternity care facility.
International breastfeeding journal
Int Breastfeed J
17
1
10.1186/s13006-022-00524-2
eng
2,022
12
3
2,022
12
3
[BACKGROUND] The in-hospital stay following childbirth is a critical time for education and support of new mothers to establish breastfeeding. The WHO/UNICEF 'Ten Steps to Successful Breastfeeding (Ten Steps)' was launched globally in 1989 to encourage maternity services to educate and support mothers to breastfeed. Th...
null
0.99
60
Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine
2,022
36,460,305
Generative adversarial networks for modelling clinical biomarker profiles with race/ethnicity.
British journal of clinical pharmacology
Br J Clin Pharmacol
89
5
10.1111/bcp.15623
eng
2,023
5
null
2,022
12
20
[AIMS] Modelling biomarker profiles for under-represented race/ethnicity groups are challenging because the underlying studies frequently do not have sufficient participants from these groups. The aim was to investigate generative adversarial networks (GANs), an artificial intelligence technology that enables realistic...
artificial intelligence; biomarkers; generative adversarial networks
1.046
176
Pharmacology; Pharmacology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,460,217
Retinopathy as an independent predictor of all-cause mortality in individuals with type 2 diabetes.
Diabetes metabolism
Diabetes Metab
49
2
10.1016/j.diabet.2022.101413
eng
2,023
3
null
2,022
11
29
[AIMS] To assess whether the presence and grade of diabetic retinopathy (DR) predict all-cause mortality, independent of risk factors for cardiovascular disease (CVD) and other complications, including diabetes-related kidney disease (DKD) and CVD, in individuals with type 2 diabetes mellitus. [METHODS] Prospective coh...
All-cause mortality; Cardiovascular disease; Diabetes-related kidney disease; Diabetic retinopathy; Type 2 diabetes
null
null
null
null
null
36,460,034
Vitamin K supplementation and bone mineral density in dialysis: results of the double-blind, randomized, placebo-controlled RenaKvit trial.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Nephrol Dial Transplant
38
10
10.1093/ndt/gfac315
eng
2,023
9
29
null
null
null
[BACKGROUND] Vitamin K deficiency is highly prevalent in patients on dialysis and may contribute to their low bone mineral density (BMD) and increased risk of fracture. This study investigated the effect of menaquinone-7 (MK-7) supplementation on BMD in patients on chronic dialysis. [METHODS] In a multicentre, double-b...
bone mineral density; chronic kidney disease; end-stage kidney disease; menaquinone-7; mineral and bone disorder
1.414
203
Medicine; Nephrology; Transplantation
Medicine
2,023
36,460,005
Musculoskeletal Injuries in Elite Collegiate Tenpin Bowling Athletes.
Journal of sport rehabilitation
J Sport Rehabil
32
3
10.1123/jsr.2022-0127
eng
2,023
3
1
2,022
12
2
[CONTEXT] Collegiate tenpin bowling participation is increasing. Accordingly, the experience level of athletes participating, factors related to performance, as well as training workload and sport specialization are likely evolving. However, literature regarding injury rates remains extremely limited. The purpose of th...
athletic training; physical therapy; prevention; rehabilitation
0.58
66
Biophysics; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science
Biochemistry, Genetics and Molecular Biology; Health Professions; Medicine
2,023
36,459,364
Multimorbidity prevalence and chronic disease patterns among tuberculosis survivors in a high-income setting.
Canadian journal of public health = Revue canadienne de sante publique
Can J Public Health
114
2
10.17269/s41997-022-00711-y
eng
2,023
4
null
2,022
12
2
[OBJECTIVES] Multimorbidity is the presence of two or more chronic health conditions. Tuberculosis (TB) survivors are known to have higher prevalence of multimorbidity, although prevalence estimates from high-income low-TB incidence jurisdictions are not available and potential differences in the patterns of chronic di...
Chronic disease; Matched group; Multimorbidity; Propensity score; Routinely collected health data; Tuberculosis
null
null
null
null
null
36,459,175
Exact Basilar Artery Occlusion Location Indicates Stroke Etiology and Recanalization Success in Patients Eligible for Endovascular Stroke Treatment.
Clinical neuroradiology
Clin Neuroradiol
33
2
10.1007/s00062-022-01236-0
eng
2,023
6
null
2,022
12
2
[INTRODUCTION] Endovascular stroke treatment (EST) is commonly performed for acute basilar artery occlusion (BAO). We aimed to identify the role of the exact location of BAO in patients receiving EST regarding the stroke etiology, recanalization success and prediction of favorable clinical outcome. [METHODS] Retrospect...
Basilar artery occlusion; Clinical outcome prediction; Mechanical thrombectomy; Recanalization success; Stroke; Stroke causes
0.794
43
Radiology, Nuclear Medicine and Imaging; Neurology
Medicine
2,023