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36,502,276
Effect of different designs of minimally invasive cantilever resin-bonded fixed dental prostheses replacing mandibular premolar: Long-term fracture load and 3D finite element analysis.
Journal of prosthodontics : official journal of the American College of Prosthodontists
J Prosthodont
32
3
10.1111/jopr.13626
eng
2,023
3
null
2,022
12
26
[PURPOSE] To evaluate the fracture load and stress magnitude of different retainer designs of minimally invasive cantilever resin-bonded fixed dental prostheses (RBFDPs) after artificial aging. [MATERIALS AND METHODS] Fifty caries-free human mandibular molars were prepared as abutments for cantilever fixed dental prost...
cantilever; fiber-reinforced composite; finite element analysis; fracture resistance; minimally invasive; resin bonded
1.475
87
Dentistry
Dentistry
2,023
36,498,237
A Comprehensive Review of Optimal Approaches to Co-Design in Health with First Nations Australians.
International journal of environmental research and public health
Int J Environ Res Public Health
19
23
10.3390/ijerph192316166
eng
2,022
12
2
2,022
12
2
[BACKGROUND] Australia's social, structural, and political context, together with the continuing impact of colonisation, perpetuates health care and outcome disparities for First Nations Australians. A new approach led by First Nations Australians is required to address these disparities. Co-design is emerging as a val...
Aboriginal and Torres Strait Islander people; First Nations peoples; cancer; co-design; community engagement; comprehensive review; participatory action research
0.828
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,022
36,497,730
Development and Validation of a Nomogram Based on Metabolic Risk Score for Assessing Lymphovascular Space Invasion in Patients with Endometrial Cancer.
International journal of environmental research and public health
Int J Environ Res Public Health
19
23
10.3390/ijerph192315654
eng
2,022
11
25
2,022
11
25
[OBJECTIVE] This study assessed the predictive value of the metabolic risk score (MRS) for lymphovascular space invasion (LVSI) in endometrial cancer (EC) patients. [METHODS] We included 1076 patients who were diagnosed with EC between January 2006 and December 2020 in Peking University People's Hospital. All patients ...
endometrial cancer; lymphovascular space invasion; metabolism; nomogram
0.828
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,022
36,497,723
Knowledge, Attitude, Risk Perception, and Health-Related Adaptive Behavior of Primary School Children towards Climate Change: A Cross-Sectional Study in China.
International journal of environmental research and public health
Int J Environ Res Public Health
19
23
10.3390/ijerph192315648
eng
2,022
11
25
2,022
11
25
[BACKGROUND] Children are disproportionately affected by climate change while evidence regarding their adaptive behavior and relevant influencing factors is limited. [OBJECTIVES] We attempted to investigate health-related adaptive behavior towards climate change for primary school children in China and explore potentia...
adaptation; behavior; children; climate change; structural equation model (SEM)
0.828
229
Health, Toxicology and Mutagenesis; Pollution; Public Health, Environmental and Occupational Health
Environmental Science; Medicine
2,022
36,496,474
Comparison of the burden of anorexia nervosa in the Middle East and North Africa region between 1990 and 2019.
Journal of eating disorders
J Eat Disord
10
1
10.1186/s40337-022-00718-3
eng
2,022
12
10
2,022
12
10
[BACKGROUND] Anorexia nervosa (AN) is a complex and heritable psychiatric disorder, which imposes significant mortality and morbidity on sufferers globally. We aimed to report the prevalence, incidence and disability-adjusted life-years (DALYs) attributable to AN in the Middle East and North Africa (MENA) region by age...
Anorexia nervosa; Epidemiology; Incidence; Middle East and North Africa; Prevalence
0.833
54
Behavioral Neuroscience; Nutrition and Dietetics; Psychiatry and Mental Health
Medicine; Neuroscience; Nursing
2,022
36,495,949
Comparison of Race-Based and Non-Race-Based Glomerular Filtration Rate Equations for the Assessment of Renal Functional Risk Before Nephrectomy.
Urology
Urology
172
null
10.1016/j.urology.2022.11.032
eng
2,023
2
null
2,022
12
8
[OBJECTIVE] To compare the performance of race-based and race-neutral estimated glomerular filtration rate (eGFR) calculators in patients undergoing kidney surgery. [METHODS] Analysis of institutional kidneys surgeries from 2006-2021 was conducted. Demographics, serum creatinine (SCr), protein dipstick, and creatinine ...
null
0.703
197
Urology
Medicine
2,023
36,495,717
A novel interaction between extracellular vimentin and fibrinogen in fibrin formation.
Thrombosis research
Thromb Res
221
null
10.1016/j.thromres.2022.11.028
eng
2,023
1
null
2,022
12
7
[INTRODUCTION] Thrombosis is frequently manifested in critically ill patients with systemic inflammation, including sepsis and COVID-19. The coagulopathy in systemic inflammation is often associated with increased levels of fibrinogen and D-dimer. Because elevated levels of vimentin have been detected in sepsis, we sou...
COVID-19; Coagulopathy; Fibrinogen; Systemic inflammation; Vimentin; sepsis
1.098
134
Hematology
Medicine
2,023
36,495,652
Non-engagement in substance use treatment among women with an unmet need for treatment: A latent class analysis on multidimensional barriers.
Drug and alcohol dependence
Drug Alcohol Depend
242
null
10.1016/j.drugalcdep.2022.109715
eng
2,023
1
1
2,022
12
5
[BACKGROUND] Women with substance use disorders experience multifaceted barriers in accessing substance use treatment. Little is known about how these barriers may aggregate. Using a person-centered approach, this study evaluates patterns of treatment barriers and the factors associated with experiencing distinct sets ...
Barriers; Female; Latent class analysis; Substance use treatment; Women
1.632
193
Pharmacology; Pharmacology; Psychiatry and Mental Health; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,495,365
Independent risk factors for an increased incidence of thromboembolism after lung transplantation.
Journal of thrombosis and thrombolysis
J Thromb Thrombolysis
55
2
10.1007/s11239-022-02748-9
eng
2,023
2
null
2,022
12
10
[BACKGROUND] Thromboembolism (TE) after lung transplantation (LTX) is associated with increased morbidity and mortality. The aim of this study is to analyze the incidence and outcome of venous and arterial thromboembolic complications and to identify independent risk factors. [PATIENTS AND METHODS] We retrospectively a...
Lung transplantation; Metabolic syndrome; Pulmonary embolism; Stroke; Thromboembolism
0.744
83
Cardiology and Cardiovascular Medicine; Hematology
Medicine
2,023
36,494,856
Associated factors and global adherence of cervical cancer screening in 2019: a systematic analysis and modelling study.
Globalization and health
Global Health
18
1
10.1186/s12992-022-00890-w
eng
2,022
12
9
2,022
12
9
[BACKGROUND] Cervical cancer screening is vital for its prevention. Adherence is a crucial indicator that implies the individual willingness to take cervical cancer screening. We aimed to estimate the global and regional adherence rates of cervical cancer screening in 2019 and identify its associated factors among gene...
Adherence; Associated factors; Cervical cancer; Meta-analysis; Modelling study; Screening; Systematic review
2.587
87
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,022
36,494,835
Bronchial eosinophils, neutrophils, and CD8 + T cells influence asthma control and lung function in schoolchildren and adolescents with severe treatment-resistant asthma.
Respiratory research
Respir Res
23
1
10.1186/s12931-022-02259-4
eng
2,022
12
9
2,022
12
9
[BACKGROUND] Studies in adult severe treatment-resistant asthma (STRA) have demonstrated heterogeneous pathophysiology. Studies in the pediatric age group are still scarce, and few include bronchial tissue analysis. [OBJECTIVE] We investigated 6-18-year-old patients diagnosed with STRA in Sao Paulo, Brazil, by characte...
Children; Endobronchial biopsy; Inflammatory cells profile; Severe asthma; Sputum
1.753
134
Pulmonary and Respiratory Medicine
Medicine
2,022
36,494,807
Parabiosis reveals the correlation between the recruitment of circulating antigen presenting cells to the retina and the induction of spontaneous autoimmune uveoretinitis.
Journal of neuroinflammation
J Neuroinflammation
19
1
10.1186/s12974-022-02660-2
eng
2,022
12
9
2,022
12
9
[BACKGROUND] Characterizing immune cells and conditions that govern their recruitment and function in autoimmune diseases of the nervous system or in neurodegenerative processes is an area of active investigation. We sought to analyze the origin of antigen presenting cells associated with the induction of retinal autoi...
Antigen presenting cells; Autoimmunity; Microglia; Origin; Parabiosis; Retina
2.439
168
Cellular and Molecular Neuroscience; Immunology; Neurology; Neuroscience
Immunology and Microbiology; Neuroscience
2,022
36,494,697
The use of posteromedial portal for arthroscopic treatment of synovial chondromatosis of the knee: a case report.
Journal of medical case reports
J Med Case Rep
16
1
10.1186/s13256-022-03667-2
eng
2,022
12
10
2,022
12
10
[BACKGROUND] The synovial chondromatosis is an uncommon proliferative metaplastic process of the synovial cells that can develop in any synovial joint. An isolated primary chondromatosis of the posterior compartment of the knee is uncommon and few cases are reported in literature. Our purpose is to describe a rare case...
Arthroscopic surgery; Case report; Posterior compartment of the knee; Posteromedial portal; Synovial chondromatosis
0.284
43
Medicine
Medicine
2,022
36,494,074
Quantifying the Value of Multigene Testing in Resected Early Stage Lung Adenocarcinoma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
J Thorac Oncol
18
4
10.1016/j.jtho.2022.11.027
eng
2,023
4
null
2,022
12
6
[INTRODUCTION] Tyrosine kinase inhibitors and immune checkpoint inhibitors (ICIs), each requiring testing for precision biomarkers, have recently been approved in the adjuvant setting. We assessed the potential value of multigene testing in early lung adenocarcinoma (LUAD). [METHODS] Using a real-world clinicogenomic d...
Early disease; Genomic biomarkers; Lung cancer; Multigene testing
7.879
190
Medicine; Oncology; Pulmonary and Respiratory Medicine
Medicine
2,023
36,494,058
Clinical outcomes of COVID-19 caused by the Alpha variant compared with one by wild type in Kobe, Japan. A multi-center nested case-control study.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
J Infect Chemother
29
3
10.1016/j.jiac.2022.11.014
eng
2,023
3
null
2,022
12
6
[OBJECTIVES] The emergence of the Alpha variant of novel coronavirus 2019 (SARS-CoV-2) is a concerning issue but their clinical implications have not been investigated fully. [METHODS] We conducted a nested case-control study to compare severity and mortality caused by the Alpha variant (B.1.1.7) with the one caused by...
Alpha variant; COVID-19; Clinical outcomes
0.579
76
Infectious Diseases; Pharmacology; Microbiology
Medicine
2,023
36,493,502
Geographic information science and the United States opioid overdose crisis: A scoping review of methods, scales, and application areas.
Social science medicine (1982)
Soc Sci Med
317
null
10.1016/j.socscimed.2022.115525
eng
2,023
1
null
2,022
11
25
[BACKGROUND] The Opioid Overdose Crisis (OOC) continues to generate morbidity and mortality in the United States, outpacing other prominent accident-related reasons. Multiple disciplines have applied geographic information science (GIScience) to understand geographical patterns in opioid-related health measures. Howeve...
Bibliometrics; Geographic information science (GIScience); Geographic information systems (GIS); Opioid crisis; Scoping review; Spatial analysis; United State
null
null
null
null
null
36,490,228
Assessment tools for elder abuse: scoping review.
Revista da Escola de Enfermagem da U S P
Rev Esc Enferm USP
56
null
10.1590/1980-220X-REEUSP-2022-0115en
eng
2,022
null
null
2,022
12
5
[OBJECTIVE] to map assessment tools for elder abuse and determine the psychometric properties of each one. [METHOD] scoping review developed according to recommendations of the JBI Institute Reviewer's Manual in databases and gray literature. [RESULTS] seventeen tools were identified for measuring situations of elder a...
null
null
null
null
null
null
36,486,178
Urinary complications after penile inversion vaginoplasty in transgender women Systematic review and meta-analysis.
Canadian Urological Association journal = Journal de l'Association des urologues du Canada
Can Urol Assoc J
17
4
10.5489/cuaj.8108
eng
2,023
4
null
null
null
null
[INTRODUCTION] Penile inversion vaginoplasty (PIV) remains the gold standard technique for vaginoplasty, a gender-affirming feminizing surgery, but has been associated with urinary complications; however, there is little literature synthesizing urinary complications after PIV surgery, and there is a need to compile the...
null
null
null
null
null
null
36,484,722
Feasibility and Safety of a Powered Exoskeleton for Balance Training for People Living with Multiple Sclerosis: A Single-Group Preliminary Study (Rapper III).
Journal of rehabilitation medicine
J Rehabil Med
54
null
10.2340/jrm.v54.4544
eng
2,022
12
9
2,022
12
9
[OBJECTIVE] To evaluate the feasibility, usability, safety, and potential health benefits of using an exoskeleton device for rehabilitation of people living with multiple sclerosis. [DESIGN] Single-group preliminary study. [SUBJECTS] Eleven adults living with multiple sclerosis, with Expanded Disability Status Scores t...
null
0.887
117
Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Sports Science
Health Professions; Medicine
2,022
36,483,210
Gut microbiota alterations may increase the risk of prescription opioid use, but not vice versa: A two-sample bi-directional Mendelian randomization study.
Frontiers in microbiology
Front Microbiol
13
null
10.3389/fmicb.2022.994170
eng
2,022
null
null
2,022
11
22
[INTRODUCTION] Gut microbiota alterations are strongly associated with prescription opioid use (POU) and multisite chronic pain (MCP). However, whether or not these associations are causal remains unknown. Therefore, we aim to explore the causal relationships between them comprehensively. [METHODS] A two-sample bi-dire...
Mendelian randomization; causality; gut microbiota; metabolites; multisite chronic pain; prescription opioid use
1.19
259
Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,022
36,483,120
Feasibility of online behavioral clinical trials: The future of weight management randomized clinical trials?
Obesity science practice
Obes Sci Pract
8
6
10.1002/osp4.615
eng
2,022
12
null
2,022
5
18
[OBJECTIVE] Behavioral weight management trials are traditionally conducted in-person. The COVID-19 shutdown halted in-person operations, forcing investigators to develop new methods for remote treatment and assessment delivery without additional funding for website development or remote equipment. This study examined ...
clinical trials; ethnicity; research design; treatment
null
null
null
null
null
36,482,318
EndHiC: assemble large contigs into chromosome-level scaffolds using the Hi-C links from contig ends.
BMC bioinformatics
BMC Bioinformatics
23
1
10.1186/s12859-022-05087-x
eng
2,022
12
8
2,022
12
8
[BACKGROUND] The application of PacBio HiFi and ultra-long ONT reads have enabled huge progress in the contig-level assembly, but it is still challenging to assemble large contigs into chromosomes with available Hi-C scaffolding tools, which count Hi-C links between contigs using the whole or a large part of contig reg...
Assembly; Contig end; Hi-C; Scaffolding
1.1
251
Applied Mathematics; Biochemistry; Computer Science Applications; Molecular Biology; Structural Biology
Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics
2,022
36,482,246
Changing a clinical pathway to increase spinal anesthesia use for elective hip arthroplasty: a single-centre historical cohort study.
Canadian journal of anaesthesia = Journal canadien d'anesthesie
Can J Anaesth
70
2
10.1007/s12630-022-02371-5
eng
2,023
2
null
2,022
12
8
[PURPOSE] International consensus recommendations support neuraxial anesthesia as the preferred anesthetic technique for total hip arthroplasty. We hypothesized that an institutional initiative to promote spinal anesthesia within a clinical pathway would result in increased use of this technique. [METHODS] We reviewed ...
change implementation; clinical pathway; general anesthesia; neuraxial anesthesia; opioids; postoperative pain; spinal anesthesia; total hip arthroplasty
null
null
null
null
null
36,482,131
Linear growth and relative weight gain in childhood and bone mass in adolescence: findings from the Pelotas (Brazil) 2004 birth cohort.
Archives of osteoporosis
Arch Osteoporos
18
1
10.1007/s11657-022-01189-4
eng
2,022
12
8
2,022
12
8
[UNLABELLED] With the objective to investigate the relationship of weight and height growth with bone mass at 11 years, we found that boys who grew in weight and height, especially at 48 months, and girls, who grew in weight at 24 months and height at 11 years, gained more bone mass. [PURPOSE] To investigate independen...
Adolescent; Bone mineral density; Cohort study; Dual-energy X-ray absorptiometry; Growth
0.717
49
Orthopedics and Sports Medicine
Medicine
2,022
36,482,093
Hospital preparedness for major incidents in Sweden: a national survey with focus on mass casualty incidents.
European journal of trauma and emergency surgery : official publication of the European Trauma Society
Eur J Trauma Emerg Surg
49
2
10.1007/s00068-022-02170-z
eng
2,023
4
null
2,022
12
8
[INTRODUCTION] Mass-casualty incidents, MCI, pose a constant threat on societies all over the world. It is essential that hospital organizations systematically prepare for such situations. A method for repeated follow-up and evaluation of hospital disaster planning is much needed. [AIMS] To evaluate Swedish hospitals´ ...
Disaster medicine; Disaster planning; Hospital preparedness; Mass casualty incident; Surge capacity; Sweden
0.661
54
Critical Care and Intensive Care Medicine; Emergency Medicine; Orthopedics and Sports Medicine; Surgery
Medicine
2,023
36,482,021
Maintenance issues of elderly patients requiring nursing care with implant treatments in dental visiting: position paper.
International journal of implant dentistry
Int J Implant Dent
8
1
10.1186/s40729-022-00458-8
eng
2,022
12
8
2,022
12
8
[PURPOSE] Japan, with an increasing number of elderly people needing long-term care in a super-aged society, urgent needs to develop the clinical guidelines on implant maintenance for elderly people with declining independence. The purpose is to categorize the troubles encountered in the care of patients with dental im...
Dental implant; Dental visiting; Elderly people needing long-term care
null
4
Medicine
Medicine
2,022
36,481,439
Factors Associated with Adverse Outcomes in Cameroonian Patients with Traumatic Brain Injury: A Cross-Sectional Study.
World neurosurgery
World Neurosurg
172
null
10.1016/j.wneu.2022.11.136
eng
2,023
4
null
2,022
12
5
[BACKGROUND] The burden of traumatic brain injury (TBI) disproportionately affects low- and middle-income countries. In Cameroon, the estimated annual incidence rate is 572 cases per 100,000 people. This study investigated factors associated with adverse outcomes in the management of Cameroonian patients with TBI. [MET...
Global health; Global neurosurgery; Global surgery; Neurosurgery; Traumatic brain injury
0.654
123
Neurology; Surgery
Medicine
2,023
36,481,247
Ferulic acid enhances insulin secretion by potentiating L-type Ca[2+] channel activation.
Journal of integrative medicine
J Integr Med
21
1
10.1016/j.joim.2022.11.003
eng
2,023
1
null
2,022
11
23
[OBJECTIVE] To investigate the effect of ferulic acid, a natural compound, on pancreatic beta cell viability, Ca[2+] channels, and insulin secretion. [METHODS] We studied the effects of ferulic acid on rat insulinoma cell line viability using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide viability as...
Calcium channels, L-type; Diabetes mellitus, type 2; Ferulic acid; Insulin; Insulin-secreting cells; Patch-clamp techniques
0.791
50
Complementary and Alternative Medicine
Medicine
2,023
36,481,237
Integrated metabolomics and molecular docking reveal berberrubine inhibits thrombosis by regulating the vitamin K catalytic cycle in mice.
European journal of pharmacology
Eur J Pharmacol
938
null
10.1016/j.ejphar.2022.175436
eng
2,023
1
5
2,022
12
5
[OBJECTIVE] Natural product berberine was reported to inhibit platelet activation and thrombosis by suppressing the class Ⅰ PI3Kβ/Rasa3/Rap1 pathway. This study aims to investigate the effects and mechanisms of berberrubine, a main metabolite of berberine, to inhibit thrombus formation. [METHODS] Carrageenan-induced mo...
Berberrubine; Metabolomics; Molecular docking; Thrombus formation; Vitamin K catalytic Cycle
1.055
210
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,023
36,481,221
Reticular Pseudodrusen Status, ARMS2/HTRA1 Genotype, and Geographic Atrophy Enlargement: Age-Related Eye Disease Study 2 Report 32.
Ophthalmology
Ophthalmology
130
5
10.1016/j.ophtha.2022.11.026
eng
2,023
5
null
2,022
12
6
[PURPOSE] To determine whether reticular pseudodrusen (RPD) status, ARMS2/HTRA1 genotype, or both are associated with altered geographic atrophy (GA) enlargement rate and to analyze potential mediation of genetic effects by RPD status. [DESIGN] Post hoc analysis of an Age-Related Eye Disease Study 2 cohort. [PARTICIPAN...
Age-Related Eye Disease Study 2; Age-related macular degeneration; Geographic atrophy; Reticular pseudodrusen; Subretinal drusenoid deposit
4.642
297
Ophthalmology
Medicine
2,023
36,480,397
World Health Organization (WHO) risk level reductions in inpatients with alcohol use disorder and comorbid anxiety disorders.
Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors
Psychol Addict Behav
37
5
10.1037/adb0000895
eng
2,023
8
null
2,022
12
8
[OBJECTIVE] Studies have demonstrated that reduced drinking without total abstinence is associated with improved outcomes in outpatients with alcohol use disorder (AUD). We sought to examine this question in AUD inpatients who have comorbid anxiety disorders, a common presentation in AUD. [METHOD] This is a secondary a...
null
1.151
127
Clinical Psychology; Medicine; Psychiatry and Mental Health
Medicine; Psychology
2,023
36,480,203
Conceptualization of Surrogate Decision-making Among Spokespersons for Chronically Ill Patients.
JAMA network open
JAMA Netw Open
5
12
10.1001/jamanetworkopen.2022.45608
eng
2,022
12
1
2,022
12
1
[IMPORTANCE] The value of advance care planning (ACP) has been the subject of recent debate because of mixed findings. This may be, in part, because trials presume that researchers and patient spokespersons share the same understanding of the role of a surrogate decision-maker. We explored how patient surrogates concep...
null
4.108
154
Medicine
Medicine
2,022
36,480,115
Increased HLA class II risk is associated with a more aggressive presentation of clinical type 1 diabetes.
Acta paediatrica (Oslo, Norway : 1992)
Acta Paediatr
112
3
10.1111/apa.16621
eng
2,023
3
null
2,022
12
25
[AIM] To determine the association of HLA class II risk with the demographic and clinical characteristics of type 1 diabetes at diagnosis. [METHODS] We conducted a register-based retrospective cohort study of 4993 Finnish children (2169 girls) - diagnosed with type 1 diabetes under the age of 15 years in 2003-2016. The...
HLA class II; clinical characteristics; diagnosis; type 1 diabetes
null
null
null
null
null
36,479,944
The Matricellular Protein SPARC Decreases in the Lacrimal Gland At Adulthood and During Inflammation.
Investigative ophthalmology visual science
Invest Ophthalmol Vis Sci
63
13
10.1167/iovs.63.13.8
eng
2,022
12
1
null
null
null
[PURPOSE] Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein abundantly expressed in basement membranes and capsules surrounding a variety of organs and tissues. It mediates extracellular matrix organization and has been implicated in cell contraction. Here, we evaluated the expression...
null
null
null
null
null
null
36,479,644
The Association of Smoking Status and Clustering of Obesity and Depression on the Risk of Early-Onset Cardiovascular Disease in Young Adults: A Nationwide Cohort Study.
Korean circulation journal
Korean Circ J
53
1
10.4070/kcj.2022.0179
eng
2,023
1
null
2,022
11
7
[BACKGROUND AND OBJECTIVES] To evaluate the impact of smoking in young adults on the risk of cardiovascular disease (CVD) and the clustering effect of behavioral risk factors such as smoking, obesity, and depression. [METHODS] A Korean nationwide population-based cohort of a total of 3,280,826 participants aged 20-39 y...
Cardiovascular diseases; Depression; Obesity; Smoking; Young adult
0.732
45
Cardiology and Cardiovascular Medicine; Internal Medicine
Medicine
2,023
36,479,258
Assessment of Pre-existing Type 2 Diabetes Mellitus Prevalence and Risk Factors Among Colorectal Cancer Patients in King Abdulaziz Medical City, Jeddah.
Cureus
Cureus
14
12
10.7759/cureus.32216
eng
2,022
12
null
2,022
12
5
[BACKGROUND] Diabetes mellitus (DM) and cancer are recognized as non-communicable chronic disorders which are among the top ten causes of death globally. In Saudi Arabia, the prevalence of type 2 DM (T2DM) and colorectal cancer (CRC) is alarmingly high. Both T2DM and CRC share common risk factors. In this study, we aim...
body mass index (bmi); cigarette smoking; colorectal cancer; kingdom of saudi arabia (ksa); type 2 diabets mellitus
null
null
null
null
null
36,479,041
HMGA1 As a Potential Prognostic and Therapeutic Biomarker in Breast Cancer.
Disease markers
Dis Markers
2022
null
10.1155/2022/7466555
eng
2,022
null
null
2,022
11
26
[BACKGROUND] High-mobility group AT-hook1 (HMGA1) protein plays an important role in various diseases. However, the contribution of HMGA1 in breast cancer remains to be tapped. [METHODS] The expression of HMGA1 was analyzed in The Cancer Genome Atlas (TCGA) and TIMER database, and immunohistochemistry was performed in ...
null
0.662
85
Biochemistry; Clinical Biochemistry; Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,478,915
Arterial remodelling in smokers and in patients with small airway disease and COPD: implications for lung physiology and early origins of pulmonary hypertension.
ERJ open research
ERJ Open Res
8
4
10.1183/23120541.00254-2022
eng
2,022
10
null
2,022
12
5
[INTRODUCTION] Pulmonary vascular remodelling in chronic obstructive pulmonary disease (COPD) has detrimental consequences for lung physiology. The aim of our study was to provide a comprehensive size-based morphometric quantification of pulmonary arterial remodelling in smokers and in patients with small airway diseas...
null
1.304
52
Pulmonary and Respiratory Medicine
Medicine
2,022
36,478,873
Prevalence and correlates of knowledge and practices regarding infection prevention and control, and triage in primary healthcare settings: A cross-sectional study in Bangladesh.
Infection prevention in practice
Infect Prev Pract
5
1
10.1016/j.infpip.2022.100258
eng
2,023
3
null
2,022
11
18
[BACKGROUND] Despite the high prevalence of healthcare-acquired infection in resource-limited settings, healthcare workers' (HCWs') knowledge and practices of infection prevention and control (IPC) and triage are not well-researched. We examined thisin Bangladesh's primary healthcare facilities (HCFs) during the COVID-...
Bangladesh; COVID-19; Infection prevention and control; Knowledge; Practices; Triage
0.547
16
Public Health, Environmental and Occupational Health; Infectious Diseases
Medicine
2,023
36,478,767
Assessment of reporting quality in randomized controlled trials of acupuncture for labor pain.
Frontiers in pain research (Lausanne, Switzerland)
Front Pain Res (Lausanne)
3
null
10.3389/fpain.2022.999162
eng
2,022
null
null
2,022
11
21
[OBJECTIVE] To evaluate the reporting quality of randomized controlled trials (RCTs) of acupuncture for labor pain, and to explore relevant factors for facilitating reporting transparency and integrity for future RCTs. [METHOD] Eight Chinese and English databases were systematically searched from their inception until ...
CONSORT; RCTs; STRICTA; acupuncture; labor pain
null
20
Anesthesiology and Pain Medicine; Health Professions; Neuroscience; Public Health, Environmental and Occupational Health
Health Professions; Medicine; Neuroscience
2,022
36,478,731
Risk cognition, agricultural cooperatives training, and farmers' pesticide overuse: Evidence from Shandong Province, China.
Frontiers in public health
Front Public Health
10
null
10.3389/fpubh.2022.1032862
eng
2,022
null
null
2,022
11
21
[INTRODUCTION] Pesticides are widely and excessively used in the world. Reducing pesticide overuse is an important measure to protect the environment and human health. [METHODS] Based on the survey data of 518 farmers in Shandong Province, China, using the Logit model to empirically test the effect of risk cognition on...
agricultural cooperatives; moderating effect; pesticide overuse; risk cognition; training
1.125
119
Public Health, Environmental and Occupational Health
Medicine
2,022
36,478,703
Percutaneous transhepatic cholangial drainage combined with intra-tumoral iodine-125 seeds implantation and chemotherapy for locally progressive pancreatic head cancer with obstructive jaundice.
Journal of contemporary brachytherapy
J Contemp Brachytherapy
14
5
10.5114/jcb.2022.121563
eng
2,022
10
null
2,022
11
30
[PURPOSE] To investigate the clinical efficacy of percutaneous transhepatic cholangial drainage (PTCD) combined with intra-tumoral iodine-125 ([125]I) particle implantation and chemotherapy in the treatment of locally advanced pancreatic head cancer (LAPHC) with obstructive jaundice. [MATERIAL AND METHODS] Twenty-one p...
locally advanced pancreatic head carcinoma; malignant obstructive jaundice; percutaneous transhepatic cholangial drainage; radioactive 125I seed implantation therapy
0.386
34
Oncology; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
36,478,652
Statins and Clinical Outcomes in Patients With Low to Moderate Risk but With Non-obstructive Carotid Plaques: The SCOPE-CP Study.
Korean circulation journal
Korean Circ J
52
12
10.4070/kcj.2022.0154
eng
2,022
12
null
null
null
null
[BACKGROUND AND OBJECTIVES] Some individuals exhibit discrepancies between risk classifications assessed using clinical factors and those obtained by vascular imaging. We aimed to evaluate whether statins provide clinical outcome benefits in patients classified as having low to moderate cardiovascular risk but with car...
Atherosclerosis; Drug therapy; Health care; Outcome assessment; Ultrasonography
0.76
45
Cardiology and Cardiovascular Medicine; Internal Medicine
Medicine
2,022
36,478,514
Marked weight loss on liraglutide 3.0 mg: Real-life experience of a Swiss cohort with obesity.
Obesity (Silver Spring, Md.)
Obesity (Silver Spring)
31
1
10.1002/oby.23596
eng
2,023
1
null
2,022
12
7
[OBJECTIVE] This study investigated the effectiveness of liraglutide 3.0 mg daily in combination with a standardized multidisciplinary intervention on body weight and body composition changes in a real-life setting. [METHODS] A prospective, observational cohort study design was used. Adult patients with BMI  35 kg/m[2]...
null
1.586
234
Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine; Nutrition and Dietetics
Biochemistry, Genetics and Molecular Biology; Medicine; Nursing
2,023
36,478,192
Assessing an active distracting technique during primary mandibular molar pulpotomy (randomized controlled trial).
Clinical and experimental dental research
Clin Exp Dent Res
9
2
10.1002/cre2.702
eng
2,023
4
null
2,022
12
8
[OBJECTIVES] This study aims to evaluate the effectiveness of two different distraction techniques (Audio Video Distraction/Video Game Distraction) in the management of anxious pediatric patients during dental treatment. [MATERIALS AND METHODS] One hundred and five children were randomly divided into three groups; Grou...
child; dental anxiety; video games
0.541
27
Dentistry
Dentistry
2,023
36,477,784
Simultaneously reassuring and unsettling: a longitudinal qualitative study of community anticipatory medication prescribing for older patients.
Age and ageing
Age Ageing
51
12
10.1093/ageing/afac293
eng
2,022
12
5
null
null
null
[BACKGROUND] The prescription of injectable anticipatory medications is widely accepted by clinicians to be key in facilitating effective last-days-of-life symptom control. Community end-of-life care and admission avoidance is particularly strongly advocated for older patients. However, patient and informal caregiver v...
anticipatory prescribing; decision-making; end-of-life care; home palliative care; older people; qualitative methods
1.738
175
Aging; Geriatrics and Gerontology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,477,687
Assessment of the performance and challenges in the implementation of the test, treat and track (T3) strategy for malaria control among children under-five years in Ghana.
PloS one
PLoS One
17
12
10.1371/journal.pone.0278602
eng
2,022
null
null
2,022
12
7
[BACKGROUND] The World Health Organization recommended the Test, Treat and Track (T3) strategy for malaria control that, every suspected malaria case should be tested prior to treatment with Artemisinin-based combination therapy (ACT) and tracked. We assessed the performance and challenges in the implementation of T3 s...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,477,647
Microvascular anastomosis of the human lacrimal gland: a concept study towards transplantation of the human lacrimal gland.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Graefes Arch Clin Exp Ophthalmol
261
5
10.1007/s00417-022-05933-x
eng
2,023
5
null
2,022
12
7
[INTRODUCTION] Severe aqueous tear deficiency is caused by primary or secondary main lacrimal gland insufficiency. The transplantation of a human lacrimal gland could become a potential treatment option to provide physiological tears with optimal properties. To this end, we performed an ex vivo study to develop a surgi...
Dry eye; Lacrimal gland; Microvascular anastomosis; Transplantation
null
null
null
null
null
36,477,595
Infection after surgical implant generation network (SIGN) nailing in treatment of long bone shaft fractures in Ethiopia: analysis of a 4-year results.
European journal of orthopaedic surgery traumatology : orthopedie traumatologie
Eur J Orthop Surg Traumatol
33
3
10.1007/s00590-022-03454-1
eng
2,023
4
null
2,022
12
7
[BACKGROUND] One of the challenge to manage long bone fracture is the risk of infection. Intramedullary nailing is the standard treatment of long bone shaft fractures. Infection from the surgical site during orthopedic management is posing postoperative burdens in different perspectives like patient perspectives and he...
Factors; Infection; Long bone fracture; Prevalence; SIGN nail
null
null
null
null
null
36,477,403
Current role of systematic biopsy in diagnosis of clinically significant prostate cancer in primary combined MRI-targeted biopsy: a high-volume single-center study.
World journal of urology
World J Urol
41
1
10.1007/s00345-022-04230-w
eng
2,023
1
null
2,022
12
7
[PURPOSE] Additive systematic biopsy (SB) contributes to prostate cancer (PCA) detection in MRI-targeted biopsy (TB). However, the reasons for this are not yet clear. We compared the performance of TB, SB and the combined approach (CB) in biopsy-naive men to determine the added value of SB for tumor grading and spatial...
Biopsy method; Clinically significant prostate cancer; Perifocal saturation biopsy; adjacent sectors; Systematic biopsy
0.975
104
Urology
Medicine
2,023
36,477,184
Time series analysis of in-hospital maternal case fatality ratio in the postpartum period according to pregnancy risks and route of delivery in the regions of Brazil, 2010-2019.
Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil
Epidemiol Serv Saude
31
3
10.1590/S2237-96222022000300011
eng
2,022
null
null
2,022
12
2
[OBJECTIVE] to analyze in-hospital maternal case fatality ratio in the postpartum period according to pregnancy risks and route of delivery, within the Brazilian National Health System, Brazil and macro-regions, 2010-2019. [METHODS] this was an ecological time-series study, using data from the Hospital Information Syst...
null
0.706
32
Multidisciplinary; Medicine; Epidemiology
Medicine; Multidisciplinary
2,022
36,476,653
Hypophosphatasia as a plausible cause of vitamin B6 associated mouth pain: a case-report.
Scandinavian journal of pain
Scand J Pain
23
2
10.1515/sjpain-2022-0108
eng
2,023
4
25
2,022
12
9
[BACKGROUND] Mouth pain has been associated with abnormal vitamin B6 levels. Hypophosphatasia is a rare genetic disease, which causes imbalances between B6 vitamers. We report the case of a patient with hypophosphatasia and burning mouth pain. [CASE PRESENTATION] A 39-year old Caucasian male with chronic burning mouth ...
burning mouth syndrome; case report; hypophosphatasia; mouth pain; vitamin B6
0.585
39
Anesthesiology and Pain Medicine; Neurology
Medicine
2,023
36,476,629
WHO Functioning and Disability Disaggregation (FDD11) tool: a reliable approach for disaggregating data by disability.
Archives of public health = Archives belges de sante publique
Arch Public Health
80
1
10.1186/s13690-022-01001-2
eng
2,022
12
7
2,022
12
7
[BACKGROUND] There is a global scarcity of good quality disability data, which has contributed to a lack of political will to address the challenges that persons with disabilities face. The current paper proposes a way forward to overcome this gap by demonstrating the psychometric properties of the World Health Organiz...
Disability; Disaggregation; Functioning; Psychometric properties
null
null
null
null
null
36,476,590
Medium- to long-term outcomes of vaginally assisted laparoscopic sacrocolpopexy in the treatment of stage III-IV pelvic organ prolapse.
BMC women's health
BMC Womens Health
22
1
10.1186/s12905-022-02105-1
eng
2,022
12
7
2,022
12
7
[BACKGROUND] Vaginally assisted laparoscopic sacrocolpopexy (VALS) refers to the placement of synthetic meshes through the vagina in addition to traditional laparoscopic sacrocolpopexy. In this study, we aimed to investigate the medium- to long-term efficacy and safety of VALS for treating stage III-IV pelvic organ pro...
Efficacy; Medium- to long-term outcomes; Pelvic organ prolapse; Safety; Vaginally assisted laparoscopic sacrocolpopexy
0.775
73
Medicine; Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,022
36,476,543
Augmented-Medication CardioPulmonary Resuscitation Trials in out-of-hospital cardiac arrest: a pilot randomized controlled trial.
Critical care (London, England)
Crit Care
26
1
10.1186/s13054-022-04248-x
eng
2,022
12
7
2,022
12
7
[BACKGROUND] Previously conducted physician-centered trials on the usefulness of vasopressin have yielded negative results; thus, patient-oriented trials have been warranted. We hypothesize that Augmented-Medication CardioPulmonary Resuscitation could be helpful for selected patients with out-of-hospital cardiac arrest...
Epinephrine; Out-of-hospital cardiac arrest; Resuscitation; Vasopressin
3.577
229
Critical Care and Intensive Care Medicine
Medicine
2,022
36,476,456
In-utero HIV exposure and cardiometabolic health among children 5-8 years: findings from a prospective birth cohort in South Africa.
AIDS (London, England)
AIDS
37
1
10.1097/QAD.0000000000003412
eng
2,023
1
1
2,022
10
19
[OBJECTIVE] To evaluate if in-utero HIV exposure is associated with adverse cardiometabolic health outcomes at 5-8 years of age. [DESIGN] Prospective cohort study. [METHODS] We enrolled a random sample of HIV-exposed but uninfected (HEU) and HIV-unexposed children from the Drakenstein Child Health study, a longitudinal...
null
1.401
233
Immunology; Immunology and Allergy; Infectious Diseases
Immunology and Microbiology; Medicine
2,023
36,476,435
Design, Synthesis, Molecular Docking, Dynamics and in vitro Evaluation of Novel 2-substituted-1-hydroxyethane-1, 1-bis(phosphonic acid) Derivatives as Human Farnesyl Pyrophosphate Synthase Inhibitors with Expected Anticancer Activity.
Current pharmaceutical design
Curr Pharm Des
29
1
10.2174/1381612829666221202114947
eng
2,023
null
null
null
null
null
[BACKGROUND] Nitrogenous bisphosphonates (NBPs) are the major class of drugs that are used to treat osteoporosis. Recently, bisphosphonates (BPs) were reported to have an anticancer effect. These agents feature a high affinity that enables them to bind strongly to the human farnesyl pyrophosphate synthase enzyme. The c...
Bisphosphonates; HFPPS; breast cancer; lung cancer; molecular docking; molecular dynamics
0.586
190
Drug Discovery; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,023
36,476,289
Pleural effusions are associated with adverse outcomes after cardiac surgery: a propensity-matched analysis.
Journal of cardiothoracic surgery
J Cardiothorac Surg
17
1
10.1186/s13019-022-02050-y
eng
2,022
12
7
2,022
12
7
[BACKGROUND] Pleural effusions commonly occur in patients recovering from cardiac surgery; however, the impact on outcomes is not well characterized. The purpose of this study is to characterize the clinical outcomes of cardiac surgery patients with pleural effusion. [METHODS] All patients undergoing cardiac surgery be...
Cardiac surgery; Intensive care medicine; Intensive care unit; Mortality; Outcomes; Pleural effusions; Postoperative
0.451
61
Surgery; Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022
36,476,091
Age and Five-Year Outcomes After Carotid Artery Stenting in Symptomatic Carotid Stenosis: A Retrospective Cohort Study.
Vascular and endovascular surgery
Vasc Endovascular Surg
57
4
10.1177/15385744221145147
eng
2,023
5
null
2,022
12
7
[BACKGROUND] Several clinical trials have reported that periprocedural risk of carotid artery stenting (CAS) increase with age. China is experiencing one of the most rapid transitions to an aging society, while the clinical outcomes of CAS in real-world China are still limited. The study aimed to compare the periproced...
age; carotid artery stenting; death; long-term outcome; stroke
0.348
56
Cardiology and Cardiovascular Medicine; Medicine; Surgery
Medicine
2,023
36,475,826
Identifying Core Competencies for Remote Delivery of Psychological Interventions: A Rapid Review.
Psychiatric services (Washington, D.C.)
Psychiatr Serv
74
3
10.1176/appi.ps.202100677
eng
2,023
3
1
2,022
12
7
[OBJECTIVE] The COVID-19 pandemic led to a rapid shift toward remote delivery of psychological interventions and transition to voice-only and video communication platforms. However, agreement is lacking on key competencies that are aligned with equitable approaches for standardized training and supervision of remote ps...
Competence; Coronavirus/COVID-19; Mental health; Psychological intervention; Research/service delivery; Telemedicine
1.543
174
Medicine; Psychiatry and Mental Health
Medicine
2,023
36,475,245
Renal Function Abnormalities among Patients with Acute Stroke at a Tertiary Hospital in Ethiopia.
Ethiopian journal of health sciences
Ethiop J Health Sci
32
6
10.4314/ejhs.v32i6.15
eng
2,022
11
null
null
null
null
[BACKGROUND] Stroke is the leading cause of neurological disability and the second commonest cause of death globally. Despite the fact that renal dysfunction is a common comorbidity of stroke, there is no data on the prevalence of renal dysfunction among patients with acute stroke in Ethiopia. The aim of this study was...
Acute stroke; Ethiopia; Mortality; Renal dysfunction
null
null
null
null
null
36,475,131
An Open-Labeled Randomized Prospective Multi-center Study to Evaluate the Efficacy and Safety of Intra-articular Injection of OSSINEXT™, an Autologous Growth Factor Concentrate (AGFC) Compared to Hyaluronic Acid (HA) in Knee Osteoarthritis.
Cureus
Cureus
14
11
10.7759/cureus.31058
eng
2,022
11
null
2,022
11
3
[BACKGROUND] Osteoarthritis (OA) is known as degenerative arthritis and is the second most common rheumatologic problem with a prevalence of 22%-39% in India. Knee OA (KOA) is a major cause of mobility impairment, particularly among females. Non-surgical treatment options for KOA include intra-articular injections of p...
growth factor; hyaluronic acid; ikdc; knee osteoarthritis; koos; vas; womac
null
null
null
null
null
36,475,049
Distribution of multiple chalazia in eyelids of pediatrics requiring surgery in southeast China: a hospital-based cross-sectional study.
World journal of pediatric surgery
World J Pediatr Surg
5
3
10.1136/wjps-2021-000408
eng
2,022
null
null
2,022
5
16
[BACKGROUND] Multiple chalazia are common in children, and many are treated by surgery. However, the distribution of different types of multiple chalazia has not been studied. This research aimed to investigate the location and number of multiple chalazia in pediatrics who need surgical treatments. [METHODS] Patients w...
Ophthalmology; Pediatrics; Surgery, Plastic
null
null
null
null
null
36,474,760
Applications of transcriptomics in support of drug development for osteoarthritis.
Osteoarthritis and cartilage open
Osteoarthr Cartil Open
3
4
10.1016/j.ocarto.2021.100221
eng
2,021
12
null
2,021
11
18
[OBJECTIVE] Understanding the heterogeneity and pathophysiology of osteoarthritis (OA) is critical to support the development of tailored disease-modifying treatments. To this aim, transcriptomics tools are highly relevant to delineate dysregulated molecular pathways and identify new therapeutic targets. [METHODS] We r...
DMOADs; Molecular profiling; Osteoarthritis; Transcriptomics
null
18
Biomedical Engineering; Orthopedics and Sports Medicine; Rehabilitation
Engineering; Medicine
2,021
36,474,627
High platelet distribution width can independently predict testicular survival in testicular torsion among patients with steady-state sickle cell anemia.
World journal of pediatric surgery
World J Pediatr Surg
5
1
10.1136/wjps-2021-000358
eng
2,022
null
null
2,022
1
5
[OBJECTIVE] This study aimed to evaluate the predictive value of platelet volume indices (PVI), such as mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT), as prognostic indicators of testicular viability in torsion patients with steady-state sickle cell anemia (SCA) who underwent sur...
biochemistry; hematology; pain; pediatrics
null
null
null
null
null
36,474,624
Addressing barriers to evidence-based medicine in pediatric surgery: an introduction to the Canadian Association of Paediatric Surgeons Evidence-Based Resource.
World journal of pediatric surgery
World J Pediatr Surg
5
1
10.1136/wjps-2021-000332
eng
2,022
null
null
2,022
1
5
[BACKGROUND] Pediatric surgical practice lags behind medicine in presence and use of evidence, primarily due to time constraints of using existing tools that are not specific to pediatric surgery, lack of sufficient patient data and unstructured pediatric surgery training methods. [METHOD] We developed, disseminated an...
evidence-based medicine; pediatrics
null
null
null
null
null
36,474,553
Evaluating the Optimal Operating Table Height for ProSeal-LMA™ Insertion.
International journal of clinical practice
Int J Clin Pract
2022
null
10.1155/2022/5118362
eng
2,022
null
null
2,022
11
17
[INTRODUCTION] ProSeal-Laryngeal Mask Airway™ (P-LMA™) is one of the commonly used laryngeal mask airways. Despite the proper insertion technique, suboptimal positioning and airway morbidity still occurs. This study explored the possibility of the operating table height position affecting successful P-LMA™ placement. [...
null
0.606
121
Medicine
Medicine
2,022
36,474,248
Investigating the pathways between swift trust and team creativity among nursing student teams in Taiwan: A moderated mediation model.
BMC nursing
BMC Nurs
21
1
10.1186/s12912-022-01118-3
eng
2,022
12
7
2,022
12
7
[BACKGROUND] Considerable theoretical and empirical work indicates that a multitude of factors are associated with team creativity in an organizational context. The complex relationships between the contributors, however, are not well understood in nursing education. This study was to take a process view investigating ...
Communication; Education; Helping behavior; Nursing; Taiwan; Trust
0.769
62
Nursing
Nursing
2,022
36,473,756
Automated Analysis of Phonoarticulatory Diadochokinesis in Tamil Speakers.
Journal of voice : official journal of the Voice Foundation
J Voice
39
3
10.1016/j.jvoice.2022.11.007
eng
2,025
5
null
2,022
12
5
[OBJECTIVES] Diadochokinetic rate (DDK) quantifies the laryngeal and oral muscle coordination, but there are insufficient baseline evidence exist, that limits the effectiveness of computerized DDK evaluation in assessing motor speech control. In the end, this study will give normative data on age and gender effects on ...
Age; Gender; Laryngeal Diadochokinetic rate; Normative data; Oral Diadochokinetic rate; Tamil speakers
0.573
114
LPN and LVN; Otorhinolaryngology; Speech and Hearing
Health Professions; Medicine; Nursing
2,024
36,473,478
Interventions to improve access to clinical trials in urologic oncology.
Canadian Urological Association journal = Journal de l'Association des urologues du Canada
Can Urol Assoc J
17
3
10.5489/cuaj.8011
eng
2,023
3
null
null
null
null
[INTRODUCTION] Most cancer patients are never enrolled in clinical trials, resulting in missed potential therapeutic benefits to patients and barriers to drug development and approval. With a focus on urologic oncology clinical trials, we reviewed the current literature on barriers to accrual and present effective inte...
null
null
null
null
null
null
36,473,400
Changing trends and factors influencing anticoagulant use in patients with acute ischemic stroke and NVAF at discharge in the NOACs era.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
32
2
10.1016/j.jstrokecerebrovasdis.2022.106905
eng
2,023
2
null
2,022
12
5
[OBJECTIVES] We sought to explore the trends and influencing factors of the use of anticoagulants in patients with acute ischemic stroke and non-valvular atrial fibrillation (NVAF) at discharge in the era of novel oral anticoagulants (NOACs). [METHODS] We recruited consecutive inpatients with acute ischemic stroke and ...
Acute ischemic stroke; Anticoagulants; Influencing factors; NOACs; Non-valvular atrial fibrillation; Trends
0.678
85
Rehabilitation; Cardiology and Cardiovascular Medicine; Neurology; Surgery
Medicine
2,023
36,473,399
Risk of, and risk factors for, vasculopathy associated with acute herpes zoster.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
32
2
10.1016/j.jstrokecerebrovasdis.2022.106891
eng
2,023
2
null
2,022
12
5
[OBJECTIVES] We aimed to summarize the known risk of vasculopathy (stroke, myocardial infarction [MI], and transient ischemic attack [TIA]) after herpes zoster (HZ) and the impact of antiviral treatment and vaccination against HZ on the risk of vasculopathy. [MATERIALS AND METHODS] A narrative literature review was con...
Antiviral treatment; Herpes zoster; Myocardial infarction; Shingles; Stroke; Transient ischemic attack; Vaccination; Vasculopathy
0.678
85
Rehabilitation; Cardiology and Cardiovascular Medicine; Neurology; Surgery
Medicine
2,023
36,472,874
Association of Glucose-Lowering Drugs With Outcomes in Patients With Diabetes Before Hospitalization for COVID-19: A Systematic Review and Network Meta-analysis.
JAMA network open
JAMA Netw Open
5
12
10.1001/jamanetworkopen.2022.44652
eng
2,022
12
1
2,022
12
1
[IMPORTANCE] Patients with COVID-19 have a high prevalence of diabetes, and diabetes and blood glucose control are determinants of intensive care unit admission and mortality. [OBJECTIVE] To evaluate the association between COVID-19-related adverse outcomes and 8 antihyperglycemic drugs in patients with diabetes who we...
null
4.108
154
Medicine
Medicine
2,022
36,472,773
The Global Landscape of Manufacturers of Follow-on Biologics: An Overview of Five Major Biosimilar Markets and 15 Countries.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy
BioDrugs
37
2
10.1007/s40259-022-00568-0
eng
2,023
3
null
2,022
12
6
[BACKGROUND] Current knowledge is limited about which manufacturers are active in the global field of biopharmaceutical product development and how many unique follow-on biologics are approved in global markets. [OBJECTIVE] This study aimed to provide a cross-sectional overview of manufacturers of follow-on biologics a...
null
1.796
84
Biotechnology; Medicine; Pharmacology; Pharmacology
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,023
36,472,727
Identification of novel PIEZO1::CBFA2T3 and INO80C::SETBP1 fusion genes in an acute myeloid leukemia patient by RNA-seq.
Molecular biology reports
Mol Biol Rep
50
2
10.1007/s11033-022-08138-x
eng
2,023
2
null
2,022
12
6
[BACKGROUND] Fusion genes are recurrent molecular aberrations in acute myeloid leukemia, with significant diagnostic and therapeutic value. The identification of novel fusion genes provides advanced biomarkers for diagnosis and facilitates the discovery of drug targets. [METHODS] Bone marrow sample was extracted from a...
Acute; Gene fusion; Leukemia; Myeloid; RNA-seq
0.649
96
Medicine; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,474,639
Perioperative mortality in children in a tertiary teaching hospital in Nigeria: a prospective study.
World journal of pediatric surgery
World J Pediatr Surg
4
1
10.1136/wjps-2020-000237
eng
2,021
null
null
2,021
3
23
[BACKGROUND] Perioperative mortality is one of the tools that can help to assess the adequacy of healthcare delivery in a nation. This audit was conducted to determine the 24-hour, 7-day and 30-day perioperative mortality rates and the predictors of mortality in a pediatric surgical cohort. [METHODS] This was a prospec...
anesthetics; sudden infant death
null
null
null
null
null
36,475,068
CCL2 induces articular chondrocyte MMP expression through ERK and p38 signaling pathways.
Osteoarthritis and cartilage open
Osteoarthr Cartil Open
3
1
10.1016/j.ocarto.2020.100136
eng
2,021
3
null
2,021
1
6
[OBJECTIVE] In previous studies, we determined an association between increased serum and articular cartilage levels of CCL2 with osteoarthritis (OA) progression, cartilage damage and increased MMP13 in cartilage. Here we analyzed CCL2 downstream signaling mediators that lead to gene expression of cartilage catabolic m...
Cartilage; Cell signaling; Chemokines; Osteoarthritis
null
18
Biomedical Engineering; Orthopedics and Sports Medicine; Rehabilitation
Engineering; Medicine
2,021
36,474,888
Symptomatic knee osteoarthritis is associated with worse but stable quality of life and physical function regardless of the compartmental involvement: Data from the OAI.
Osteoarthritis and cartilage open
Osteoarthr Cartil Open
2
4
10.1016/j.ocarto.2020.100117
eng
2,020
12
null
2,020
11
1
[OBJECTIVE] To test whether combined patellofemoral and tibiofemoral osteoarthritis (OA), in addition to symptoms, is associated with greater changes in quality of life and objective physical function measures when compared with asymptomatic isolated tibiofemoral osteoarthritis. [DESIGN] Of the 4796 participants in the...
Knee osteoarthritis; Physical function; Quality of life; Symptoms
null
18
Biomedical Engineering; Orthopedics and Sports Medicine; Rehabilitation
Engineering; Medicine
2,020
36,474,889
Framework for modulating ambulatory load in the context of in vivo mechanosensitivity of articular cartilage.
Osteoarthritis and cartilage open
Osteoarthr Cartil Open
2
4
10.1016/j.ocarto.2020.100108
eng
2,020
12
null
2,020
10
9
[OBJECTIVE] Different stress modalities have been used to provoke a load induced mechanoresponse in blood markers of articular cartilages. The challenge in in vivo experiments is to alter specific loading characteristics. Here, we aimed to develop a load modification framework that changes ambulatory load magnitude wit...
Ambulatory biomechanics; Bodyweight support; In vivo cartilage mechanosensitivity; Load modification
null
18
Biomedical Engineering; Orthopedics and Sports Medicine; Rehabilitation
Engineering; Medicine
2,020
36,474,915
Early prediction of acute kidney injury in neonates with cardiac surgery.
World journal of pediatric surgery
World J Pediatr Surg
3
2
10.1136/wjps-2019-000107
eng
2,020
null
null
2,020
6
25
[BACKGROUND] Acute kidney injury (AKI) occurs in 42%-64% of the neonatal patients experiencing cardiac surgery, contributing to postoperative morbidity and mortality. Current diagnostic criteria, which are mainly based on serum creatinine and hourly urine output, are not sufficiently sensitive and precise to diagnose n...
cardiac surgery; intensive care; neonatology; nephrology
null
null
null
null
null
36,474,555
Effect of total joint replacement in hip osteoarthritis on serum COMP and its correlation with mechanical-functional parameters of gait analysis.
Osteoarthritis and cartilage open
Osteoarthr Cartil Open
2
1
10.1016/j.ocarto.2020.100034
eng
2,020
3
null
2,020
2
5
[OBJECTIVE] To study the effect of total hip replacement (THR) on serum cartilage oligomeric matrix protein concentration (sCOMP) and its correlation with joint loading during gait in patients with unilateral hip osteoarthritis. [DESIGN] In this prospective multimodal (clinical, biomechanical, biochemical) study blood ...
COMP; Gait analysis; Joint loading; Osteoarthritis; Serum biomarker; Total hip arthroplasty
null
18
Biomedical Engineering; Orthopedics and Sports Medicine; Rehabilitation
Engineering; Medicine
2,020
36,533,946
Effect of Delayed Anterior Cruciate Ligament Reconstruction on Repair of Concomitant Medial Meniscus Tears in Young Athletes.
The American journal of sports medicine
Am J Sports Med
51
2
10.1177/03635465221142325
eng
2,023
2
null
2,022
12
19
[BACKGROUND] Delayed anterior cruciate ligament (ACL) reconstruction (ACLR) is associated with an increased risk of meniscal injury. Limited data are available regarding the relationship between surgical delay and meniscal repairability in the setting of ACLR in young patients. [PURPOSE] To determine whether time from ...
ACL reconstruction; ACL tear; meniscal repair; meniscal tear; surgical delay
2.363
277
Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,023
36,533,924
Pediatric acquired brain injury resources for educators: a multi-year scan of Canadian-relevant internet resources.
Brain injury
Brain Inj
37
4
10.1080/02699052.2022.2158230
eng
2,023
3
21
2,022
12
19
[BACKGROUND] Acquired Brain Injury (ABI) is the leading cause of death and disability in children, yet educators report a lack of knowledge about ABI and supporting students with ABI. With no formal learning about ABI, education professionals may turn to the internet for information. [OBJECTIVES] To find online resourc...
Environmental scan; acquired brain injury; educators; students; traumatic brain injury
0.645
122
Developmental and Educational Psychology; Neurology; Neuroscience
Medicine; Neuroscience; Psychology
2,023
36,533,899
Long-term outcomes of aplastic anemia with cytogenetic abnormalities at diagnosis.
European journal of haematology
Eur J Haematol
110
4
10.1111/ejh.13913
eng
2,023
4
null
2,023
1
7
[OBJECTIVES] To elucidate the clinical characteristics of AA patients with cytogenetic abnormalities. [METHODS] We retrospectively screened 30 patients (30/1206, 2.5%) with cytogenetic abnormalities from 1206 patients with severe and very severe AA who received immunosuppressive therapy (IST) during the years 2012-2019...
Aplastic anemia; Cytogenetic abnormalities; Immunosuppressive therapy
0.944
99
Medicine; Hematology
Medicine
2,023
36,533,881
Quantification of MR spectra by deep learning in an idealized setting: Investigation of forms of input, network architectures, optimization by ensembles of networks, and training bias.
Magnetic resonance in medicine
Magn Reson Med
89
5
10.1002/mrm.29561
eng
2,023
5
null
2,022
12
19
[PURPOSE] The aims of this work are (1) to explore deep learning (DL) architectures, spectroscopic input types, and learning designs toward optimal quantification in MR spectroscopy of simulated pathological spectra; and (2) to demonstrate accuracy and precision of DL predictions in view of inherent bias toward the tra...
active learning; bias; deep learning; ensemble of networks; magnetic resonance spectroscopy; model fitting; quantification
1.343
257
Radiology, Nuclear Medicine and Imaging
Medicine
2,023
36,533,600
Intravenous immunoglobulin for acute exacerbation of fibrotic idiopathic interstitial pneumonias.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG
Sarcoidosis Vasc Diffuse Lung Dis
39
4
10.36141/svdld.v39i4.13682
eng
2,022
12
19
2,022
12
19
[BACKGROUND AND AIM] Acute exacerbation (AE) of idiopathic pulmonary fibrosis (IPF) is a fatal condition with no established treatment. Intravenous immunoglobulin (IVIG) is a unique therapy with both anti-inflammatory and anti-infective effects. Therefore, we hypothesized that IVIG may have a positive effect on AE of i...
null
0.519
66
Medicine; Immunology and Allergy; Internal Medicine; Pulmonary and Respiratory Medicine
Medicine
2,022
36,533,501
Building and Sustaining Community Partnerships: An Organizational Network Analysis in a Low-resource Neighborhood.
Progress in community health partnerships : research, education, and action
Prog Community Health Partnersh
16
4
10.1353/cpr.2022.0073
eng
2,022
null
null
null
null
null
[BACKGROUND] Launched in 2012, the Claremont Healthy Village Initiative (CHVI) is a partnership focused on fostering community collaboration, addressing the social determinants of health, and reducing health disparities. Partners include local community centers, schools, after-school programs, health care providers, a ...
null
null
null
null
null
null
36,533,299
Severe malaria-related disability in African children: a scoping review.
Disability and rehabilitation
Disabil Rehabil
46
1
10.1080/09638288.2022.2157053
eng
2,024
1
null
2,022
12
19
[PURPOSE] Disability is a consequence of severe malaria for a significant proportion of African children. This scoping review aims to describe the impact of severe malaria on African children according to current literature using an international biopsychical classification and framework of disability and functioning. ...
Africa; Severe malaria; children; disability; scoping review
0.972
140
Rehabilitation
Medicine
2,024
36,533,223
Factors influencing the mental health of caregivers of children with cerebral palsy.
Frontiers in pediatrics
Front Pediatr
10
null
10.3389/fped.2022.920744
eng
2,022
null
null
2,022
11
30
[OBJECTIVES] Caregivers of children with cerebral palsy have a huge burden which might affect their mental health. This study aimed to determine the different factors affecting the mental health of caregivers of children with cerebral palsy and to raise awareness among healthcare providers. [METHODS] A cross-sectional ...
anxiety; caregivers; cerebral palsy; depression; stress
0.798
83
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,531,864
Chemotherapy Dose Shapes the Expression of Immune-Interacting Markers on Cancer Cells.
Cellular and molecular bioengineering
Cell Mol Bioeng
15
6
10.1007/s12195-022-00742-y
eng
2,022
12
null
2,022
10
1
[INTRODUCTION] Tumor and immune cells interact through a variety of cell-surface proteins that can either restrain or promote tumor progression. The impacts of cytotoxic chemotherapy dose and delivery route on this interaction profile remain incompletely understood, and could support the development of more effective c...
Chemo-immunotherapy; Controlled drug release; Doxorubicin; Tumor immune interaction
0.734
48
Biochemistry, Genetics and Molecular Biology; Modeling and Simulation
Biochemistry, Genetics and Molecular Biology; Mathematics
2,022
36,531,736
One-year results from the Assessing MICRO-vascular resistances via IMR to predict outcome in ST-elevation myocardial infarction patients with multivessel disease undergoing primary PCI (AMICRO) trial.
Frontiers in cardiovascular medicine
Front Cardiovasc Med
9
null
10.3389/fcvm.2022.1051174
eng
2,022
null
null
2,022
12
2
[BACKGROUND] In ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary angioplasty (PPCI) the index of microcirculatory resistance (IMR) correlates to the extent of myocardial damage and left ventricular (LV) function recovery. Data on the IMR time-course and impact on clinical out...
STEMI; fractional flow reserve (FFR); microvascular resistance; multivessel disease (MVD)
1.391
81
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,531,637
A case of Legionnaires' disease with severe rhabdomyolysis misdiagnosed as COVID-19.
Heliyon
Heliyon
8
12
10.1016/j.heliyon.2022.e12341
eng
2,022
12
null
2,022
12
10
[BACKGROUND] COVID-19 case numbers have begun to rise with the recently reported Omicron variant. In the last two years, COVID-19 is the first diagnosis that comes to mind when a patient is admitted with respiratory symptoms and pulmonary ground-glass opacities. However, other causes should be kept in mind as well. Her...
COVID-19 pandemic; Legionella; Rhabdomyolysis; SARS-CoV-2
0.609
115
Multidisciplinary
Multidisciplinary
2,022
36,531,510
Prevalence and clinical characteristics of T2DM patients with OTUD3 gene rs78466831 SNP at a single academic center in China.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
13
null
10.3389/fendo.2022.1059641
eng
2,022
null
null
2,022
12
2
[BACKGROUND] A novel, rare OTUD3 c.863GA (rs78466831) in humans has been reported associated with diabetes, but the prevalence and clinical characteristics of T2DM patients with rs78466831 have not been reported before. [OBJECTIVE] To investigate the prevalence and clinical characteristics of T2DM patients with rs78466...
OTUD3; clinical characteristics; diabetes retinopathy; gene; type 2 diabetes
1.278
138
Endocrinology, Diabetes and Metabolism
Medicine
2,022
36,531,049
Gastrectomy for cancer beyond life expectancy. A comprehensive analysis of oncological gastric surgery in Germany between 2008 and 2018.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.1032443
eng
2,022
null
null
2,022
11
30
[INTRODUCTION] Major gastric surgery for distal esophageal and gastric cancer has a strong impact on the quality of life, morbidity, and mortality. Especially in elderly patients reaching their life expectancy, the responsible use and extent of gastrectomy are imperative to achieve a balance between harm and benefit. I...
clinical outcome; comorbidity; elderly patients; esophageal cancer; gastrectomy; gastric cancer; mortality
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,531,037
Construction of machine learning-based models for cancer outcomes in low and lower-middle income countries: A scoping review.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.976168
eng
2,022
null
null
2,022
12
1
[BACKGROUND] The impact and utility of machine learning (ML)-based prediction tools for cancer outcomes including assistive diagnosis, risk stratification, and adjunctive decision-making have been largely described and realized in the high income and upper-middle-income countries. However, statistical projections have ...
artificial intelligence; cancer; low-income countries; lower-middle-income countries; machine learning
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,531,015
Non-tumoral uptake of [68]Ga-FAPI-04 PET: A retrospective study.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.989595
eng
2,022
null
null
2,022
12
1
[OBJECTIVE] Fibroblast activation protein (FAP)-targeting radiopharmaceutical based on the FAP-specific inhibitor (FAPI) is considered as a potential alternative agent to FDG for tumor-specific imaging. However, FAP is also expressed in normal adult tissues. The aim of this study was to explore the image features of no...
68 Ga-FAPI-04; SUV; benign uptake; multicenter retrospective study; physiological uptake
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,530,925
Retinal changes in patients with idiopathic inflammatory myopathies: A case-control study in the MyoCite cohort.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.1065960
eng
2,022
null
null
2,022
11
30
[BACKGROUND] Retinal changes are the window to systemic vasculature. Therefore, we explored retinal changes in patients with Idiopathic inflammatory myopathies (IIM) as a surrogate for vascular health. [METHODS] Adult and Juvenile IIM patients (2017 ACR/EULAR criteria), visiting a tertiary care center in 2021 were enro...
idiopathic inflammatory myositis; myopathy; retina; vascular health; vasculopathy
0.926
102
Medicine
Medicine
2,022
36,530,871
Cortisol awake response imbalance as an indicator of acute central serous chorioretinopathy: Relationship with choriocapillaris and choroidal features.
Frontiers in medicine
Front Med (Lausanne)
9
null
10.3389/fmed.2022.1030352
eng
2,022
null
null
2,022
11
30
[PURPOSE] The purpose of the present study was to measure in central serous chorioretinopathy (CSC) the salivary cortisol awake response (CAR) delta percentage (Δ%) variation, a distinct and robust indicator of cortisol rhythm during wakefulness, commonly proposed as a marker of hypothalamic-pituitary adrenal (HPA) axi...
central serous chorioretinopathy (CSC); choroidal vascularity index (CVI); flow signal void area; optical coherence tomography (OCT); optical coherence tomography angiography (OCTA); salivary cortisol awake response; subfoveal choroidal thickness
0.926
102
Medicine
Medicine
2,022
36,530,680
Development of a multi-component tobacco cessation training package utilizing multiple approaches of intervention development for health care providers and patients attending non-communicable disease clinics of Punjab, India.
Frontiers in public health
Front Public Health
10
null
10.3389/fpubh.2022.1053428
eng
2,022
null
null
2,022
12
2
[BACKGROUND] Providing patients with personalized tobacco cessation counseling that is culturally sensitive, and disease-specific from healthcare providers (HCPs) as part of their routine consultations is an approach that could be incorporated, using existing healthcare systems such as the Non-Communicable Disease (NCD...
India; NCD clinics; behavior; intervention development; multi-component; socio-cultural; tobacco cessation
1.125
119
Public Health, Environmental and Occupational Health
Medicine
2,022
36,530,663
Seroepidemiology of pertussis in the east of China: Estimates of incidence of infection in adolescents and adults pre- and post-COVID-19.
Frontiers in public health
Front Public Health
10
null
10.3389/fpubh.2022.1054617
eng
2,022
null
null
2,022
12
1
[INTRODUCTION] The dramatic decrease in the number of reported cases of pertussis during COVID-19 pandemic has been underestimated. The objective was to compare the estimated incidence rate of pertussis in populations pre- and post-COVID-19 pandemic by analyzing the anti-pertussis toxin (anti-PT) IgG and anti-filamento...
adolescents and adults; antibodies; pertussis; seroprevalence; vaccination
1.125
119
Public Health, Environmental and Occupational Health
Medicine
2,022