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36,458,877
Defining an abnormal p53 immunohistochemical stain in Barrett's oesophagus-related dysplasia: a single-positive crypt is a sensitive and specific marker of dysplasia.
Histopathology
Histopathology
82
4
10.1111/his.14848
eng
2,023
3
null
2,023
1
16
[AIMS] p53 is an independent risk stratification marker in Barrett's oesophagus (BE), but no universally accepted definition exists for abnormal p53 staining. Herein, we assess p53 stains in two cohorts to: (1) define abnormal p53 staining in BE-related dysplasia (BERD) and (2) assess the specificity and sensitivity of...
Barrett's oesophagus; dysplasia; p53
1.392
145
Histology; Medicine; Pathology and Forensic Medicine
Medicine
2,023
36,458,578
Cholesterol Triggers Nuclear Co-Association of Androgen Receptor, p160 Steroid Coactivators, and p300/CBP-Associated Factor Leading to Androgenic Axis Transactivation in Castration-Resistant Prostate Cancer.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Cell Physiol Biochem
56
S4
10.33594/000000592
eng
2,022
12
2
null
null
null
[BACKGROUND/AIMS] Cholesterol modulates intratumoral androgenic signaling in prostate cancer; however, the molecular mechanisms underlying these changes in castration-resistant prostate cancer (CRPC) are not fully elucidated. Herein, we investigated the effect of cholesterol on androgen receptor (AR) coactivators expre...
Prostate cancer; Hypercholesterolemic model; p160
0.827
118
Physiology
Biochemistry, Genetics and Molecular Biology
2,022
36,458,518
Pathways from developmental vulnerabilities in early childhood to schizotypy in middle childhood.
The British journal of clinical psychology
Br J Clin Psychol
62
1
10.1111/bjc.12405
eng
2,023
3
null
2,022
12
2
[OBJECTIVES] Childhood disturbances in social, emotional, language, motor and cognitive functioning, and schizotypy have each been implicated as precursors of schizophrenia-spectrum disorders. We investigated whether relationships between early childhood developmental vulnerabilities and childhood schizotypy are mediat...
cognitive vulnerability; developmental antecedents; path analysis; schizophrenia-spectrum disorders; schizotaxia; schizotypy
1.73
104
Clinical Psychology; Medicine
Medicine; Psychology
2,023
36,457,725
Renoprotective effect of chronic treatment with sodium-glucose cotransporter 2 inhibitors and its associated factors in Japanese patients with chronic heart failure and diabetes.
International journal of cardiology. Heart vasculature
Int J Cardiol Heart Vasc
43
null
10.1016/j.ijcha.2022.101152
eng
2,022
12
null
2,022
11
26
[BACKGROUND] Recent clinical trials have shown that sodium-glucose cotransporter 2 (SGLT2) inhibitors have beneficial effects on renal function in heart failure patients. This study confirmed the renoprotective effect of treatment with SGLT2 inhibitors in Japanese patients with chronic heart failure and diabetes and fu...
Glomerular filtration rate; Renal function; SGLT2 inhibitor; Venous congestion
null
null
null
null
null
36,457,513
Characterizing microbiota and metabolomics analysis to identify candidate biomarkers in lung cancer.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.1058436
eng
2,022
null
null
2,022
11
15
[BACKGROUND] Lung cancer is the leading malignant disease and cause of cancer-related death worldwide. Most patients with lung cancer had insignificant early symptoms so that most of them were diagnosed at an advanced stage. In addition to factors such as smoking, pollution, lung microbiome and its metabolites play vit...
16S rRNA amplicon sequencing; biomarker; lung cancer; lung microbiota; metabolomics
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,457,504
Integrated network pharmacology and experimental verification to investigate the mechanisms of YYFZBJS against colorectal cancer via CDK1/PI3K/Akt signaling.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.961653
eng
2,022
null
null
2,022
11
15
[BACKGROUND] Colorectal cancer (CRC) is a common digestive tract malignancy with rising incidence and morbidity worldwide during recent years. Yi-Yi-Fu-Zi-Bai-Jiang-San (YYFZBJS), a traditional Chinese medicine formula, has showed positive effects against cancers. However, the mechanisms underlying its anticancer effec...
PI3K/Akt pathway; YYFZBJS; apoptosis; cell cycle; colorectal cancer; network pharmacology
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,457,177
Combining functional exercises with exercise training in COPD: a randomized controlled trial.
Physiotherapy theory and practice
Physiother Theory Pract
40
5
10.1080/09593985.2022.2148146
eng
2,024
5
null
2,022
12
1
[INTRODUCTION] Increasing physical activity in daily life (PADL) in chronic obstructive pulmonary disease (COPD), mainly in short-term training programs, is still a challenge. The combination of functional exercises with aerobic and resistance training may be a strategy to improve PADL and limitations in activities of ...
Chronic obstructive pulmonary disease; exercise training; physical activity
0.683
61
Physical Therapy, Sports Therapy and Rehabilitation
Health Professions
2,024
36,457,128
Incorporation of DNA methylation quantitative trait loci (mQTLs) in epigenome-wide association analysis: application to birthweight effects in neonatal whole blood.
Clinical epigenetics
Clin Epigenetics
14
1
10.1186/s13148-022-01385-6
eng
2,022
12
1
2,022
12
1
[BACKGROUND] Epigenome-wide association studies (EWAS) have helped to define the associations between DNA methylation and many clinicopathologic and developmental traits. Since DNA methylation is affected by genetic variation at certain loci, EWAS associations may be potentially influenced by genetic effects. However, ...
Birthweight; DNA methylation; DNA methylation quantitative trait loci (mQTL); Epigenome-wide association analysis (EWAS)
2.014
86
Developmental Biology; Genetics; Genetics; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,457,097
The value of the ACEF II score in Chinese patients with elective and non-elective cardiac surgery.
BMC cardiovascular disorders
BMC Cardiovasc Disord
22
1
10.1186/s12872-022-02946-6
eng
2,022
12
2
2,022
12
2
[OBJECTIVE] To evaluate the value of the ACEF II score in predicting postoperative hospital death and acute kidney injury requiring dialysis (AKI-D) in Chinese patients. [METHODS] This retrospective study included adult patients who underwent cardiopulmonary bypass open heart surgery between January 2010 and December 2...
Acute kidney injury; Cardiac surgery; Death; Emergency surgery; Risk assessment
0.601
76
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,456,956
When the technical is also normative: a critical assessment of measuring health inequalities using the concentration index-based indices.
Population health metrics
Popul Health Metr
20
1
10.1186/s12963-022-00299-y
eng
2,022
12
1
2,022
12
1
[BACKGROUND] Concentration index-based measures are one of the most popular tools for estimating socioeconomic-status-related health inequalities. In recent years, several variants of the concentration index have been developed that are designed to correct for deficiencies of the standard concentration index and which ...
Concentration index; Erreygers index; Income-related health inequality; Measurement of inequality; Normative values; Wagstaff index
0.955
67
Public Health, Environmental and Occupational Health; Epidemiology
Medicine
2,022
36,456,906
Dopamine receptor D3 is related to prognosis in human hepatocellular carcinoma and inhibits tumor growth.
BMC cancer
BMC Cancer
22
1
10.1186/s12885-022-10368-y
eng
2,022
12
2
2,022
12
2
[BACKGROUND] Dopamine receptors have been reported to play important roles in cancer progression. However, the role of dopamine receptor D3 (DRD3) in hepatocellular carcinoma (HCC) remains unclear. [METHODS] The expression of DRD3 was detected by immunohistochemistry and real-time qPCR. The prognostic value of DRD3 in ...
Dopamine receptor D3; ERK pathway; Hepatocellular carcinoma; Prognosis; Target therapy
1.137
171
Genetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,456,861
Comparison of peripheral extension, acquisition time, and image chromaticity of Optos, Clarus, and EIDON systems.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Graefes Arch Clin Exp Ophthalmol
261
5
10.1007/s00417-022-05923-z
eng
2,023
5
null
2,022
12
2
[PURPOSE] To evaluate differences in acquisition time, peripheral extension, and chromaticity between 3 different commercialized ultra-wide-field (UWF) fundus cameras. [METHODS] Patients were prospectively enrolled from 07/2021 to 11/2021. Patients underwent fundus photography with the following scanning protocols: (1)...
Chromaticity; Fundus camera; Optos Silverstone; Ultra-wide-field (UWF); Zeiss Clarus; iCare EIDON
null
null
null
null
null
36,456,449
Relationship of sleep regularity with device-based sedentary behavior time and physical activity time in working adults.
Sleep health
Sleep Health
9
1
10.1016/j.sleh.2022.10.002
eng
2,023
2
null
2,022
11
28
[OBJECTIVES] This study aimed to investigate the association of sleep regularity with time spent in sedentary behavior (SB) and physical activity (PA) in adults with full-time jobs. [METHODS] This was a cross-sectional study. Adults aged 21-64 years with full-time jobs were recruited between August 2019 and December 20...
Full-time jobs; Sleep variability; Social jet lag; Triaxial accelerometers
1.261
51
Behavioral Neuroscience; Health; Neuropsychology and Physiological Psychology; Social Sciences
Neuroscience; Psychology; Social Sciences
2,023
36,456,114
Severe myalgic encephalomyelitis/chronic fatigue syndrome in children and young people: a British Paediatric Surveillance Unit study.
Archives of disease in childhood
Arch Dis Child
108
3
10.1136/archdischild-2022-324319
eng
2,023
3
null
2,022
12
1
[OBJECTIVES] Primary objective: to determine the point prevalence and incidence rate of severe myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in children aged 5-16 years over 13 months. [SECONDARY OBJECTIVES] to describe the demographic features, symptoms, impact on activities of daily living, school atten...
child health; chronic fatigue syndrome; paediatrics
0.935
169
Pediatrics, Perinatology and Child Health
Medicine
2,023
36,455,905
Impact of Benzodiazepine Use on Length of Stay and 30-Day ED Visits among Hospitalized Hematopoietic Stem Cell Transplant Recipients.
Southern medical journal
South Med J
115
12
10.14423/SMJ.0000000000001481
eng
2,022
12
null
null
null
null
[OBJECTIVES] This study assesses the impact of benzodiazepine (BNZ) use on length of stay (LOS) and 30-day emergency department (ED) visits after hematopoietic stem cell transplant (HSCT). [METHODS] Adult patients (18 years and older) who underwent an allogeneic or an autologous HSCT from 2015 to 2018 at the study site...
null
null
null
null
null
null
36,455,862
Is the conservative treatment of sacral insufficiency fractures still up to date? Retrospective clinical observational study in 46 patients.
Orthopaedics traumatology, surgery research : OTSR
Orthop Traumatol Surg Res
109
2
10.1016/j.otsr.2022.103495
eng
2,023
4
null
2,022
11
28
[BACKGROUND] According to current forecasts, our society will grow older and older, so that the proportion of 6% of the German population from 2017 who were 80 years or older will increase further. The frequency of falls in this patient population lead to a further increase of sacral insufficiency fractures. [HYPOTHESI...
Fragility Fractures of the Pelvis; Sacral insufficiency fracture; geriatric medicine
null
null
null
null
null
36,455,810
The association between physical frailty and injurious falls and all-cause mortality as negative health outcomes in people living with HIV: A systematic review and meta-analysis.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Int J Infect Dis
126
null
10.1016/j.ijid.2022.11.030
eng
2,023
1
null
2,022
11
29
[OBJECTIVES] Physical frailty is one of the major concerns among older people living with HIV (PLWH). This meta-analysis aimed to explore the association between physical frailty and negative health outcomes among PLWH. [METHODS] We systematically searched six electronic databases including PubMed, Embase, Web of Scien...
HIV; Meta-analysis; Negative health outcomes; Physical frailty
1.435
140
Infectious Diseases; Medicine; Microbiology
Medicine
2,023
36,455,789
Low aerobic capacity in McArdle disease: A role for mitochondrial network impairment?
Molecular metabolism
Mol Metab
66
null
10.1016/j.molmet.2022.101648
eng
2,022
12
null
2,022
11
28
[BACKGROUND] McArdle disease is caused by myophosphorylase deficiency and results in complete inability for muscle glycogen breakdown. A hallmark of this condition is muscle oxidation impairment (e.g., low peak oxygen uptake (VO2peak)), a phenomenon traditionally attributed to reduced glycolytic flux and Krebs cycle an...
Aerobic capacity; Cytoskeleton and mitochondrial network; Glycogen; McArdle disease; Skeletal muscle
2.809
115
Cell Biology; Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,022
36,455,301
Association between premorbid sarcopenia and neurological deterioration in patients with acute ischemic stroke.
Clinical neurology and neurosurgery
Clin Neurol Neurosurg
224
null
10.1016/j.clineuro.2022.107527
eng
2,023
1
null
2,022
11
17
[OBJECTIVE] Sarcopenia is associated with poor outcomes in patients with stroke. This study aimed to investigate the association between premorbid sarcopenia and neurological deterioration (ND) in patients with acute ischemic stroke. To the best of our knowledge, there have been no studies on this topic. [METHODS] In t...
Ischemic stroke; Neurological deterioration; Older; Sarcopenia
0.608
89
Medicine; Surgery; Neurology
Medicine
2,023
36,455,142
Analysis of the Mechanism of Action of Kushen in the Treatment of Tuberculosis Based on Network Pharmacology.
Alternative therapies in health and medicine
Altern Ther Health Med
29
2
null
eng
2,023
3
null
null
null
null
[CONTEXT] Drug-resistant tuberculosis (TB), especially multidrug-resistant TB, has continued to increase and pan-drug-resistant TB and even fully drug-resistant TB have emerged, bringing great challenges to the treatment of TB. Development of new, safe, and effective antituberculosis drugs is an urgent need. [OBJECTIVE...
null
0.282
78
Complementary and Alternative Medicine; Medicine
Medicine
2,023
36,455,071
Safety and Efficacy of Repeated Corneal Collagen Crosslinking in Progressive Keratoconus.
Cornea
Cornea
42
4
10.1097/ICO.0000000000003165
eng
2,023
4
1
2,022
11
30
[PURPOSE] Keratoconus is a progressive visually impairing disorder. Despite the beneficial effects of epithelial off-crosslinking (CXL) on the stabilization of keratoconus, progression may still occur. We report the efficacy and safety of a repeated CXL for significant progression of keratoconus after a single CXL proc...
null
1.019
141
Ophthalmology
Medicine
2,023
36,454,798
Effectiveness and safety of low-dose versus standard-dose rivaroxaban and apixaban in patients with atrial fibrillation.
PloS one
PLoS One
17
12
10.1371/journal.pone.0277744
eng
2,022
null
null
2,022
12
1
[BACKGROUND] Low-dose direct oral anticoagulant (DOAC) use is quite prevalent in clinical practice, but evidence of its effectiveness and safety compared with high-dose DOAC in patients with atrial fibrillation (AF) remains limited. We aimed to assess the effectiveness and safety of low-dose and high-dose DOACs in pati...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,454,598
Systematic reviews on platelet transfusions: Is there unnecessary duplication of effort? A scoping review.
Vox sanguinis
Vox Sang
118
1
10.1111/vox.13387
eng
2,023
1
null
2,022
12
1
[BACKGROUND AND OBJECTIVES] Platelet transfusions are used across multiple patient populations to prevent and correct bleeding. This scoping review aimed to map the currently available systematic reviews (SRs) and evidence-based guidelines in the field of platelet transfusion. [MATERIALS AND METHODS] A systematic liter...
decision support; haemostasis; platelet apheresis; platelet transfusion; scoping review; thrombocytopenia; viscoelastic
0.699
96
Hematology; Medicine
Medicine
2,023
36,454,495
Unexpected results found in larvae samples from two postmortem forensic cases.
Forensic toxicology
Forensic Toxicol
40
1
10.1007/s11419-021-00601-x
eng
2,022
1
null
2,021
11
6
[PURPOSE] In forensics, entomological specimens can be used as additional/alternative matrices to detect xenobiotics when human specimens are limited in their application. Despite some advantages over implementing putrefied human remains, most medico-legal laboratories do not include entomotoxicological procedures as r...
Benzodiazepines; Entomotoxicology; Necrophagous larvae; New psychoactive substances (NPS); Postmortem; Synthetic cannabinoids
null
null
null
null
null
36,454,378
Risk Factors for Glycemic Control in Hospitalized Patients with Type 2 Diabetes Receiving Continuous Subcutaneous Insulin Infusion Therapy.
Diabetes therapy : research, treatment and education of diabetes and related disorders
Diabetes Ther
14
1
10.1007/s13300-022-01342-9
eng
2,023
1
null
2,022
12
1
[INTRODUCTION] Patients with diabetes are confronted with numerous obstacles to achieve adequate glycemic control during hospitalization. The aim of this study was to explore the risk factors associated with glycemic control in hospitalized patients with type 2 diabetes mellitus (T2DM) treated with continuous subcutane...
Continuous subcutaneous insulin infusion; Glycemic control; Hospitalized patients; Risk factors; Type 2 diabetes mellitus
0.938
59
Endocrinology, Diabetes and Metabolism; Internal Medicine
Medicine
2,023
36,453,848
The top 10 research priorities in psoriatic arthritis: a James Lind Alliance Priority Setting Partnership.
Rheumatology (Oxford, England)
Rheumatology (Oxford)
62
8
10.1093/rheumatology/keac676
eng
2,023
8
1
null
null
null
[OBJECTIVES] To identify and prioritize the top 10 research questions for PsA. [METHODS] The British Psoriatic Arthritis Consortium (BritPACT) formed a Priority Setting Partnership (PSP) comprising of people living with PsA, carers and clinicians, supported by the James Lind Alliance (JLA). This PSP followed the establ...
James Lind Alliance; Priority Setting Partnership; consensus; psoriatic arthritis
1.721
205
Pharmacology; Rheumatology
Medicine
2,023
36,453,835
Operator versus material influence on film thickness using adhesive resin cement or pre-heated resin composite.
Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]
J Esthet Restor Dent
35
3
10.1111/jerd.12988
eng
2,023
4
null
2,022
12
1
[OBJECTIVE] There is a growing interest in using pre-heated composites instead of dual-cured cements when luting indirect restorations. This study evaluated the film thickness obtained from two pre-heated composites and two resin cements, by two different operators. The influence of the materials and the level of exper...
film thickness; luting cements; operator expertise level; pre-heated resin composites
1.086
79
Dentistry
Dentistry
2,023
36,453,729
Anteromedialization Tibial Tubercle Osteotomy Improves Patellar Contact Forces: A Cadaveric Model of Patellofemoral Dysplasia.
The American journal of sports medicine
Am J Sports Med
51
2
10.1177/03635465221138287
eng
2,023
2
null
2,022
12
1
[BACKGROUND] Patellofemoral (PF) dysplasia is common in patients with recurrent patellar instability. Tibial tubercle osteotomy (TTO) is performed with goals of correcting patellar maltracking and redistributing contact forces across the PF joint. The biomechanical effects of TTO in the setting of PF dysplasia have not...
Elmslie Trillat; Fulkerson; anteromedialization; patellar instability; patellofemoral; tibial tubercle osteotomy; trochlear dysplasia
2.363
277
Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,023
36,453,459
A novel comprehensive radiation shielding system eliminates need for personal lead aprons in the catheterization laboratory.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography Interventions
Catheter Cardiovasc Interv
101
1
10.1002/ccd.30490
eng
2,023
1
null
2,022
12
1
[OBJECTIVES] This clinical study evaluated the efficacy of a novel radiation shielding system for the cardiac catheterization laboratory designed to provide comprehensive protection that obviates the need for personal lead aprons. [BACKGROUND] Invasive Cardiologists are exposed to occupational health hazards related di...
occupational hazard; occupational health; radiation safety
0.948
134
Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,023
36,453,343
Clinical presentation and treatment outcomes of an algorithmic approach to uveal effusion syndrome.
Indian journal of ophthalmology
Indian J Ophthalmol
70
12
10.4103/ijo.IJO_1221_22
eng
2,022
12
null
null
null
null
[PURPOSE] To describe the clinical features and treatment outcomes in spontaneous uveal effusion syndrome (UES). [METHODS] A 10-year retrospective chart review of UES patients from a tertiary eye center was carried out. Optical coherence tomography (OCT), fundus fluorescein angiography, and ultrasound biomicroscopy (UB...
Anterior chamber maintainer; UES; exudative RD; ocular ultrasonography; sclerectomy; sub-retinal fluid drainage; uveal effusion syndrome
0.666
79
Ophthalmology
Medicine
2,022
36,453,316
Safety and efficacy of Aurolab aqueous drainage implant in refractory glaucoma: A prospective study.
Indian journal of ophthalmology
Indian J Ophthalmol
70
12
10.4103/ijo.IJO_1391_22
eng
2,022
12
null
null
null
null
[PURPOSE] This study was conducted to assess the intraocular pressure (IOP) control and postoperative complications following a non-valved glaucoma drainage device (GDD) surgery in refractory glaucoma. [METHODS] This was a prospective interventional study conducted on patients with glaucoma refractory to maximal medica...
Aurolab aqueous drainage implant (AADI); glaucoma drainage device; glaucoma surgery; intraocular pressure (IOP); refractory glaucoma
0.666
79
Ophthalmology
Medicine
2,022
36,453,306
Efficacy of dorzolamide in improving ocular blood flow in patients with open-angle glaucoma: The Indian carbonic anhydrase inhibitor trial.
Indian journal of ophthalmology
Indian J Ophthalmol
70
12
10.4103/ijo.IJO_1055_22
eng
2,022
12
null
null
null
null
[PURPOSE] Impaired ocular blood flow is an important risk factor in the pathogenesis of open-angle glaucoma (OAG). Studies have reported that dorzolamide 2% may be effective in improving ocular blood flow (OBF) in OAG patients. The objective of this study was to determine the efficacy of dorzolamide 2% (DORZOX, Cipla L...
Dorzolamide; end diastolic velocity; ocular perfusion pressure; open-angle glaucoma
0.666
79
Ophthalmology
Medicine
2,022
36,453,283
Tropoelastin Improves Post-Infarct Cardiac Function.
Circulation research
Circ Res
132
1
10.1161/CIRCRESAHA.122.321123
eng
2,023
1
6
2,022
12
1
[BACKGROUND] Myocardial infarction (MI) is among the leading causes of death worldwide. Following MI, necrotic cardiomyocytes are replaced by a stiff collagen-rich scar. Compared to collagen, the extracellular matrix protein elastin has high elasticity and may have more favorable properties within the cardiac scar. We ...
collagen; echocardiography; elastin; heart; myocardial infarction; therapeutics; tropoelastin
4.903
402
Cardiology and Cardiovascular Medicine; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,023
36,453,165
Sleep-Opt-In: A Randomized Controlled Pilot Study to Improve Sleep and Glycemic Variability in Adults With Type 1 Diabetes.
The science of diabetes self-management and care
Sci Diabetes Self Manag Care
49
1
10.1177/26350106221136495
eng
2,023
2
null
2,022
12
1
[PURPOSE] The purpose of this study was to evaluate the feasibility and acceptability of a technology-assisted behavioral sleep intervention (Sleep-Opt-In) and to examine the effects of Sleep-Opt-In on sleep duration and regularity, glucose indices, and patient-reported outcomes. Short sleep duration and irregular slee...
null
0.855
85
Health Professions; Health; Endocrinology, Diabetes and Metabolism
Health Professions; Medicine; Social Sciences
2,023
36,453,040
Accelerated discharge after aseptic revision knee arthroplasty is not associated with early readmission and reoperation.
The bone joint journal
Bone Joint J
104-B
12
10.1302/0301-620X.104B12.BJJ-2022-0372.R2
eng
2,022
12
null
null
null
null
[AIMS] In the last decade, perioperative advancements have expanded the use of outpatient primary total knee arthroplasty (TKA). Despite this, there remains limited data on expedited discharge after revision TKA. This study compared 30-day readmissions and reoperations in patients undergoing revision TKA with a hospita...
Accelerated discharge; Anesthesiologists; Aseptic revision; Revision total knee; Short-stay arthroplasty; TKAs; cancer; chronic obstructive pulmonary disease; diabetes mellitus; hypertension; medical comorbidities; primary total knee arthroplasty; revision surgeries; revision total knee arthroplasty
null
null
null
null
null
36,452,189
An Incidental Detection of a Cryptic Complex Chromosome Rearrangement Found During NGS Based PGT-SR: A Case Report.
Journal of reproduction infertility
J Reprod Infertil
23
4
10.18502/jri.v23i4.10817
eng
2,022
null
null
null
null
null
[BACKGROUND] Complex chromosome rearrangements (CCRs) involve more than 2 chromosomal breakpoints and cause the exchanges of chromosomal segments between two or more chromosomes. The carriers of CCRs have normal phenotypes, but they have a higher risk of reproductive failure. [CASE PRESENTATION] This paper presents a c...
Chromosomal translocation; Chromosome abnormalities; Next generation sequencing; Preimplantation genetic testing
null
null
null
null
null
36,452,081
Confirmation of the southern African distribution of the marine sponge Hymeniacidon perlevis (Montagu, 1814) in the context of its global dispersal.
PeerJ
PeerJ
10
null
10.7717/peerj.14388
eng
2,022
null
null
2,022
11
25
[BACKGROUND] Intertidal rocky shore surveys along the South African coastline (∼3,000 km) have demonstrated the presence and abundance of the encrusting orange sponge Hymeniacidon perlevis (Montagu, 1814), a well-known globally distributed species. After analysing the southern African populations, we gained a better un...
Barcoding; COI; Haplotype networks; ITS; Population structure; Porifera; Rocky intertidal area; Southern Africa; Temperate coasts
0.695
124
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,022
36,452,033
Birefringence effect studies of collagen formed by nonenzymatic glycation using dual-retarder Mueller polarimetry.
Journal of biomedical optics
J Biomed Opt
27
8
10.1117/1.JBO.27.8.087001
eng
2,022
8
null
2,022
8
4
[SIGNIFICANCE] Nonenzymatic glycation of collagen covalently attaches an addition of sugar molecules that initially were involved in a reversibly reaction with amino groups on the protein. Due to the ultimate formation of stable irreversible advanced glycation end products, the process of glycation leads to abnormal ir...
Mueller polarimetry; birefringence; collagen; nonenzymatic glycation
0.824
165
Atomic and Molecular Physics, and Optics; Electronic, Optical and Magnetic Materials; Biomaterials; Biomedical Engineering
Engineering; Materials Science; Physics and Astronomy
2,022
36,452,025
A qualitative exploration of the views of paramedics regarding the identification of cardiovascular risk factors in the pre-hospital environment.
British paramedic journal
Br Paramed J
7
1
10.29045/14784726.2022.06.7.1.19
eng
2,022
6
1
null
null
null
[BACKGROUND] Cardiovascular disease remains the most prominent cause of death in England. Healthcare professionals have been encouraged to identify cardiovascular risk factors (CVRFs). The aim of this study was to explore how paramedics contribute to the identification of CVRFs in the pre-hospital setting, through thei...
cardiovascular disease; paramedic; risk factors
null
null
null
null
null
36,451,897
Antenatal care in Nepal: a qualitative study into missed opportunities in the first trimester.
AJOG global reports
AJOG Glob Rep
2
4
10.1016/j.xagr.2022.100127
eng
2,022
11
null
2,022
11
4
[BACKGROUND] Use of timely antenatal care has been identified as key to facilitating healthy pregnancies worldwide. Although considerable investment has been made to enhance maternal health services in Nepal, approximately one-third of women do not attend antenatal care until after the first trimester (late). These wom...
South Asia; focus groups; folic acid; low-income countries; pregnancy care; ultrasound scanning
0.312
11
Obstetrics and Gynecology
Medicine
2,022
36,451,512
Automated identification and quantification of traumatic brain injury from CT scans: Are we there yet?
Medicine
Medicine (Baltimore)
101
47
10.1097/MD.0000000000031848
eng
2,022
11
25
null
null
null
[BACKGROUND] The purpose of this study was to conduct a systematic review for understanding the availability and limitations of artificial intelligence (AI) approaches that could automatically identify and quantify computed tomography (CT) findings in traumatic brain injury (TBI). [METHODS] Systematic review, in accord...
null
null
null
null
null
null
36,451,360
Alterations in metamemory capacity and neural correlates in a subtype of subjective cognitive decline.
NeuroImage. Clinical
Neuroimage Clin
36
null
10.1016/j.nicl.2022.103255
eng
2,022
null
null
2,022
11
7
[BACKGROUNDS] Subjective cognitive decline (SCD), one of the important clinical indicators for preclinical Alzheimer's disease (AD), is primarily defined as self-perceived cognitive decline without objective evidence for cognitive impairment. However, the accuracy of their self-evaluation of cognition is unclear. This ...
Cortical thickness; Metamemory; Slight cognitive impairment; Subjective cognitive decline; fMRI
null
null
null
null
null
36,451,220
5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages.
Journal of inflammation (London, England)
J Inflamm (Lond)
19
1
10.1186/s12950-022-00319-6
eng
2,022
11
30
2,022
11
30
[BACKGROUND] Acute lung injury (ALI) arises from sepsis or bacterial infection, which are life-threatening respiratory disorders that cause the leading cause of death worldwide. 5-Methoxyflavone, a methylated flavonoid, is gaining increased attention for its various health benefits. In the current study, we investigate...
5-Methoxyflavone; Acute lung injury; LPS; Methylated flavonoid; Nrf2
0.341
12
Cardiology and Cardiovascular Medicine
Medicine
2,001
36,451,204
Safety of linezolid in patients with decreased renal function and trough monitoring: a systematic review and meta-analysis.
BMC pharmacology toxicology
BMC Pharmacol Toxicol
23
1
10.1186/s40360-022-00628-9
eng
2,022
11
30
2,022
11
30
[BACKGROUND] Linezolid causes hematological toxicity, mostly thrombocytopenia, which leads to treatment discontinuation and failure. Recent studies revealed that during linezolid therapy, the incidence of treatment-related hematological toxicity is significantly higher in patients with decreased renal function (DRF) th...
Hematological toxicity; Linezolid; Renal; Thrombocytopenia; Trough concentrations
null
null
null
null
null
36,451,109
Radiomics-based prediction of response to immune checkpoint inhibitor treatment for solid cancers using computed tomography: a real-world study of two centers.
BMC cancer
BMC Cancer
22
1
10.1186/s12885-022-10344-6
eng
2,022
11
30
2,022
11
30
[BACKGROUND] Immune checkpoint inhibitors (ICIs) represent an approved treatment for various cancers; however, only a small proportion of the population is responsive to such treatment. We aimed to develop and validate a plain CT-based tool for predicting the response to ICI treatment among cancer patients. [METHODS] D...
Radiomics; immune checkpoint inhibitor; marker; predictive model; response
1.137
171
Genetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,450,324
Comparison between human olfactory sensitivity in the fasted and fed states: A systematic review and meta-analysis.
Appetite
Appetite
181
null
10.1016/j.appet.2022.106395
eng
2,023
2
1
2,022
11
28
[INTRODUCTION] Olfaction is tightly regulated by internal status such as hunger level. The influence of fasted and fed states on olfactory sensitivity in humans has reached mixed results. This study aims to systematically review, integrate and meta-analyze evidence of the impact of fasting on olfactory sensitivity in h...
Fasting; Fasting time; Food odor; Meta-analyses; Non-food odor; Olfactory sensitivity
1.265
190
Nutrition and Dietetics; Psychology
Nursing; Psychology
2,023
36,450,290
Nirmatrelvir/Ritonavir Prescription Rate and Outcomes in Coronavirus Disease 2019: A Single Center Study.
Infection chemotherapy
Infect Chemother
54
4
10.3947/ic.2022.0123
eng
2,022
12
null
2,022
11
18
[BACKGROUND] Nirmatrelvir/ritonavir was Korea's first oral antiviral agent to treat coronavirus disease 2019 (COVID-19). We analyzed the nirmatrelvir/ritonavir prescription rate and treatment outcomes in treatment-eligible patients with COVID-19 receiving home-based care. [MATERIALS AND METHODS] We retrospectively coll...
COVID-19; Nirmatrelvir and Ritonavir Drug Combination; Outcome
null
null
null
null
null
36,449,870
The Combination of the Mini-Punch Technique and Photodynamic Therapy for the Treatment of Mandibular Keloids and Hypertrophic Scars.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
Dermatol Surg
48
12
10.1097/DSS.0000000000003621
eng
2,022
12
1
2,022
10
21
[BACKGROUND] Mandibular keloids and hypertrophic scars can exert significant effects on the appearance of a patient. However, current treatments are not effective in all cases. Consequently, it is vital to identify a safe and effective treatment method. [OBJECTIVE] To investigate the therapeutic effect of the mini-punc...
null
0.56
146
Dermatology; Medicine; Surgery
Medicine
2,022
36,449,672
Epidemiology of ectopia lentis and outcomes after surgery in a Danish population.
Journal of cataract and refractive surgery
J Cataract Refract Surg
48
12
10.1097/j.jcrs.0000000000001008
eng
2,022
12
1
null
null
null
[PURPOSE] To describe the causes of ectopia lentis (EL) and the outcomes after surgery in a Danish population. [SETTING] The Eye Clinic Rigshospitalet and Kennedy Center in Copenhagen. [DESIGN] Retrospective cohort study. [METHODS] Medical records of patients with nontraumatic EL born after 1980 and seen at the Eye Cli...
null
0.741
169
Surgery; Ophthalmology; Sensory Systems
Medicine; Neuroscience
2,022
36,449,502
Experience of switching from a daily to a less frequent administration of injection treatments.
PloS one
PLoS One
17
11
10.1371/journal.pone.0278293
eng
2,022
null
null
2,022
11
30
[BACKGROUND] Daily injections of recombinant human growth hormone are the standard of care to treat growth failure due to pediatric growth hormone deficiency (GHD). While effective, daily injections are burdensome and can compromise adherence. In recent years, novel injection treatments requiring less frequent administ...
null
0.885
467
Multidisciplinary
Multidisciplinary
2,022
36,449,307
Association of Interleukin 6 Inhibition With Ziltivekimab and the Neutrophil-Lymphocyte Ratio: A Secondary Analysis of the RESCUE Clinical Trial.
JAMA cardiology
JAMA Cardiol
8
2
10.1001/jamacardio.2022.4277
eng
2,023
2
1
null
null
null
[IMPORTANCE] The neutrophil-lymphocyte ratio (NLR) independently predicts atherosclerotic events and is a potential biomarker for residual inflammatory risk. Interleukin (IL) 1β inhibition reduces the NLR, but whether inhibition of IL-6, a cytokine downstream of IL-1, also lowers the NLR is uncertain. [OBJECTIVE] To ev...
null
6.231
127
Cardiology and Cardiovascular Medicine
Medicine
2,023
36,449,153
Treatment and follow-up of late onset intra hepatic bile duct stones in congenital biliary dilatation.
Pediatric surgery international
Pediatr Surg Int
39
1
10.1007/s00383-022-05321-w
eng
2,022
11
30
2,022
11
30
[PURPOSE] The postoperative course after surgery for congenital biliary dilatation (CBD) has some complications. Intrahepatic bile duct (IHBD) stones were known as a late complication. We report on the treatment and long-term follow-up of postoperative IHBD stones in our department. [METHODS] Patients who underwent CBD...
Congenital biliary dilatation; Double-balloon enteroscopy; Intrahepatic bile duct; Percutaneous transhepatic cholangiodrainage
0.575
78
Medicine; Pediatrics, Perinatology and Child Health; Surgery
Medicine
2,022
36,449,085
Difference in the fibular attachment structure between the superior and inferior fascicles of the anterior talofibular ligament using ultrasonography and histological examinations.
Surgical and radiologic anatomy : SRA
Surg Radiol Anat
44
12
10.1007/s00276-022-03049-9
eng
2,022
12
null
2,022
11
30
[PURPOSE] The anterior talofibular ligament (ATFL) is divided into superior (SB) and inferior bands (IB). Although the differences in length and width are known, the structure of the fibular attachment had not been elucidated. The present study aimed to clarify the differences in the fibular attachment structure betwee...
Ankle anatomy; Anterior talofibular ligament (ATFL); Double bands; Enthesis structure; Histological study
0.408
75
Anatomy; Surgery; Pathology and Forensic Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,022
36,448,869
The IlluminOss® System: a solution in elderly patients with upper limbs bone metastases.
European review for medical and pharmacological sciences
Eur Rev Med Pharmacol Sci
26
1 Suppl
10.26355/eurrev_202211_30291
eng
2,022
11
null
null
null
null
[OBJECTIVE] The IlluminOss® System (IS) based on photodynamic bone stabilization (PBS) is a recent option in between the minimally invasive surgical techniques available to treat bone metastases when medical or radiation therapy is neither effective nor indicated, and major surgery is not possible. In this study, the r...
null
null
null
null
null
null
36,448,767
Geriatric Nutritional Risk Index as a Predictor of Prognosis in Metastatic Renal Cell Carcinoma Treated with Nivolumab.
Nutrition and cancer
Nutr Cancer
75
2
10.1080/01635581.2022.2152061
eng
2,023
null
null
2,022
11
30
[BACKGROUND] The Geriatric Nutritional Risk Index (GNRI) has been reported as a screening tool to assess the nutrition-related risk with mortality in older patients and those with the various diseases. However, the prognostic value of GNRI in metastatic renal cell carcinoma (mRCC) patients receiving nivolumab therapy r...
null
0.627
135
Medicine; Nutrition and Dietetics; Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine; Nursing
2,023
36,448,753
Psychometric properties of the Arabic version of the meaningful use of speech scale (Arabic MUSS).
Disability and rehabilitation
Disabil Rehabil
45
25
10.1080/09638288.2022.2148299
eng
2,023
12
null
2,022
11
30
[PURPOSE] To examine the construct, discriminative, and predictive validity, and the test-retest reliability of the Arabic Meaningful Use of Speech Scale (MUSS). [METHODS] Parents of 102 children with cochlear implantation (CI) with a matching control group of 102 children with normal hearing completed the Arabic-MUSS ...
Arabic; Cochlear implantation; Meaningful Use of Speech Scale; children; psychometrics
0.796
140
Rehabilitation
Medicine
2,023
36,448,735
Fingerprick blood samples to measure serum natalizumab concentrations.
Multiple sclerosis (Houndmills, Basingstoke, England)
Mult Scler
29
3
10.1177/13524585221136448
eng
2,023
3
null
2,022
11
30
[BACKGROUND] Natalizumab via subcutaneous administration was recently approved for patients with multiple sclerosis. [OBJECTIVE] In light of personalized extended dosing, in which treatment intervals are prolonged to a concentration cut-off, it would be preferable to measure natalizumab drug concentrations in capillary...
Multiple sclerosis; capillary; extended interval dosing; fingerprick; natalizumab
null
null
null
null
null
36,448,307
Olfactory-gustatory simultaneity judgments: A preliminary study on the congruency-dependent temporal window of multisensory binding.
Brain and behavior
Brain Behav
13
1
10.1002/brb3.2821
eng
2,023
1
null
2,022
11
30
[BACKGROUND] A greater congruency of audio and video expands the temporal binding window (TBW). A similar phenomenon may occur with a combination of odor and taste, which are the main components of flavor. [OBJECTIVE] TBW is defined as the temporal resolution of synchrony perception. The larger the TBW, the lower the r...
congruency; simultaneity judgment; synchrony perception; temporal binding window
0.908
69
Behavioral Neuroscience
Neuroscience
2,023
36,447,896
Endoscopically observed outer membrane of chronic subdural hematoma after endovascular embolization of middle meningeal artery.
Surgical neurology international
Surg Neurol Int
13
null
10.25259/SNI_886_2022
eng
2,022
null
null
2,022
11
11
[BACKGROUND] Embolization of the middle meningeal artery (MMA) has been established for chronic subdural hematoma (CSDH). Neuroendoscopic observation of the outer membrane of the hematoma was carried out after embolization. The treatment mechanism of embolization is discussed, focusing on the vasculature and inflammati...
Chronic subdural hematoma; Embolization; Inflammation; Neuroendoscope; Outer membrane
0.256
48
Surgery; Neurology
Medicine
2,022
36,447,885
Failure of tandem flow diversion for intracranial aneurysms: Literature review and illustrative case.
Surgical neurology international
Surg Neurol Int
13
null
10.25259/SNI_944_2022
eng
2,022
null
null
2,022
11
11
[BACKGROUND] Flow diverters are becoming one of the main endovascular procedures used to treat aneurysms. Flow diverter devices (FDDs) have multiple types approved for endovascular procedure use. Although their indications are not well described, they are usually used for large or giant, wide-necked, and recurrent aneu...
Flow diverter devices; Intracranial aneurysms; Stent migration
0.256
48
Surgery; Neurology
Medicine
2,022
36,447,829
Recurrent Cushing Syndrome From Metastatic Adrenocortical Carcinoma With Fumarate Hydratase Allelic Variant.
AACE clinical case reports
AACE Clin Case Rep
8
6
10.1016/j.aace.2022.09.003
eng
2,022
null
null
2,022
9
17
[BACKGROUND] Adrenal Cushing syndrome (CS) is usually benign in etiology; however, although rarely, it can be due to adrenocortical carcinoma (ACC); in which case, diagnosis and management are quite complicated. [CASE REPORT] A 34-year-old woman presented with worsening confusion, weight gain, new-onset diabetes, and h...
ACC, adrenocortical carcinoma; ACTH, adrenocorticotropic hormone; CS, Cushing syndrome; CT, computed tomography; adrenal cancer; adrenal mass; hypercortisolism; metastases
0.288
15
Endocrinology, Diabetes and Metabolism
Medicine
2,022
36,447,804
Urinary Screening in Asymptomatic Indian Children: A Cross Sectional Epidemiological Study.
EJIFCC
EJIFCC
33
3
null
eng
2,022
10
null
2,022
10
28
[BACKGROUND AND AIMS] Early detection and management of renal abnormalities in children can reduce the progression of paediatric chronic kidney disease. Currently, data on the prevalence of routine abnormal urinary parameters are scarce in Indian population. This study aims to identify the prevalence of asymptomatic ki...
chronic kidney disease; hematuria; pediatric population; proteinuria; urinary screening
null
null
null
null
null
36,447,628
The Effects of Six Weeks of Fasted Aerobic Exercise on Body Shape and Blood Biochemical Index in Overweight and Obese Young Adult Males.
Journal of exercise science and fitness
J Exerc Sci Fit
21
1
10.1016/j.jesf.2022.11.003
eng
2,023
1
null
2,022
11
11
[BACKGROUND/OBJECTIVE] The effects of fasted aerobic exercise on body composition and whether it causes adverse effects remain controversial. This study was to compare the effects of fasted and non-fasted aerobic exercise on body shape and blood biochemical indexes in overweight and obese young adult males, and observe...
Adverse effects; Blood biochemical index; Body shape index; Fasting aerobic exercise; Obesity
0.743
35
Pharmaceutical Science; Pharmacology; Physical Therapy, Sports Therapy and Rehabilitation; Public Health, Environmental and Occupational Health; Sports Science
Health Professions; Medicine; Nursing; Pharmacology, Toxicology and Pharmaceutics
2,023
36,447,384
Lived experiences of end-of-life communication among nursing home staff: An interpretive phenomenological study.
Journal of advanced nursing
J Adv Nurs
79
2
10.1111/jan.15489
eng
2,023
2
null
2,022
11
29
[AIMS] To explore and understand lived experiences of end-of-life communication among nursing home staff. [DESIGN] Interpretive phenomenological study. [METHODS] In-person, semi-structured, in-depth interviews were conducted from May to August 2021 with 21 nursing home staff members involved in end-of-life communicatio...
communication; end of life; hermeneutics; lifeworld existentials; nurse; nursing home; qualitative study
1.218
187
Nursing
Nursing
2,023
36,447,216
Evaluation of a skills-based peer-led art therapy online-group for people with emotion dysregulation.
Borderline personality disorder and emotion dysregulation
Borderline Personal Disord Emot Dysregul
9
1
10.1186/s40479-022-00203-y
eng
2,022
11
30
2,022
11
30
[OBJECTIVE] We developed and piloted a novel art-based online skills program led by a peer mental health professional with lived experience of complex mental health, including Borderline Personality Disorder (BPD). Key challenges of living with BPD and emotion dysregulation were addressed through artmaking informed by ...
Borderline personality disorder; Emotional dysregulation; Group therapy; Intentional peer support; Lived experience; Online art therapy; Peer; Psychotherapy; Qualitative research
1.394
37
Clinical Psychology; Psychiatry and Mental Health; Biological Psychiatry
Medicine; Neuroscience; Psychology
2,022
36,457,974
The impact on health-related quality of life of mixed mental and physical multimorbidity in adults aged 60 years and older: secondary analysis of primary care data.
Archives of medical science : AMS
Arch Med Sci
18
6
10.5114/aoms.2020.92914
eng
2,022
null
null
2,020
2
6
[INTRODUCTION] Given the number of patients with mental conditions who receive treatment within the primary care (PC) context, and the high prevalence of multimorbidity (especially in older people), there is a need to study mental-physical multimorbidity (MPM) in this population and context. This study sought to identi...
geriatric psychiatry; multimorbidity; primary health care; quality of life
0.799
66
Medicine
Medicine
2,022
36,508,985
Etiology of pulmonary hypertension in multiple myeloma: A case series and literature review.
Respiratory medicine
Respir Med
206
null
10.1016/j.rmed.2022.107071
eng
2,023
1
null
2,022
12
7
[BACKGROUND] Multiple myeloma is often complicated by pulmonary hypertension through a variety of mechanisms. These mechanisms include pulmonary hypertension (PH) due to concomitant cardiac amyloid, high output heart failure due to anemia or lytic bone lesions, chronic thromboembolic pulmonary hypertension (CTEPH), tox...
null
1.18
145
Pulmonary and Respiratory Medicine
Medicine
2,023
36,508,935
Cannabis use in Attention - Deficit/Hyperactivity Disorder (ADHD): A scoping review.
Journal of psychiatric research
J Psychiatr Res
157
null
10.1016/j.jpsychires.2022.11.029
eng
2,023
1
null
2,022
11
25
[INTRODUCTION] Treatments for Adult ADHD include stimulants, two non-stimulant medications, as well as cognitive-behavioral therapy (CBT). These pharmacological agents are often associated with side effects, contributing to poor treatment adherence. Patients with ADHD have regularly stated that cannabis has helped impr...
ADHD; Cannabidiol; Cannabis; Review; THC; Treatment
1.553
172
Biological Psychiatry; Psychiatry and Mental Health
Medicine; Neuroscience
2,023
36,508,855
Impact of surgery on fertility among patients with deep infiltrating endometriosis.
European journal of obstetrics, gynecology, and reproductive biology
Eur J Obstet Gynecol Reprod Biol
280
null
10.1016/j.ejogrb.2022.12.004
eng
2,023
1
null
2,022
12
7
[OBJECTIVE] The aim of the study was to investigate pregnancy and live birth rate after surgical resection of rectosigmoid deep infiltrating endometriosis (DIE), and study if complications affect these rates. [STUDY DESIGN] Historical case series. 193 patients with rectosigmoid DIE and pregnancy intention undergoing a ...
Assisted reproductive technologies; Bowel endometriosis; Colorectal resection; Deep infiltrating endometriosis; Pregnancy rate
null
null
null
null
null
36,508,271
Unravelling the Mechanistic Role of ACE2 and TMPRSS2 in Hypertension: A Risk Factor for COVID-19.
Current hypertension reviews
Curr Hypertens Rev
18
2
10.2174/1573402118666220816090809
eng
2,022
null
null
null
null
null
[BACKGROUND] This review explores the mechanistic action of angiotensin-converting enzyme- 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2) in the renin-angiotensinaldosterone system (RAAS) that predisposes hypertensive patients to the adverse outcome of severe COVID-19. [METHODS AND RESULTS] Entry of SARS-CoV-2 ...
ACE2; ACEI; ARBs; COVID-19; RAAS; TMPRSS2; hypertension
null
null
null
null
null
36,508,249
The Global, Regional, and National Burden and Trends of NAFLD in 204 Countries and Territories: An Analysis From Global Burden of Disease 2019.
JMIR public health and surveillance
JMIR Public Health Surveill
8
12
10.2196/34809
eng
2,022
12
12
2,022
12
12
[BACKGROUND] Nonalcoholic fatty liver disease (NAFLD) poses a substantial socioeconomic burden and is becoming the fastest growing driver of chronic liver disease, potentially accompanied by a poor prognosis. [OBJECTIVE] We aim to elucidate the global and regional epidemiologic changes in NAFLD during the past 30 years...
Global Burden of Disease Study 2019; diabetes mellitus type 2; disability-adjusted life-years; epidemiologic change; incidence; ischemic heart disease; mortality; non-alcoholic fatty liver disease; prevalence; stroke
1.547
64
Health Informatics; Public Health, Environmental and Occupational Health
Medicine
2,022
36,508,244
Social Media Recruitment Strategies to Recruit Pregnant Women Into a Longitudinal Observational Cohort Study: Usability Study.
Journal of medical Internet research
J Med Internet Res
24
12
10.2196/40298
eng
2,022
12
12
2,022
12
12
[BACKGROUND] Use of social media for study recruitment is becoming increasingly common. Previous studies have typically focused on using Facebook; however, there are limited data to support the use of other social media platforms for participant recruitment, notably in the context of a pregnancy study. [OBJECTIVE] Our ...
Facebook; Instagram; Twitter; fraudulent responses; pregnancy; questionnaires; recruitment; social media; surveys
1.992
214
Health Informatics
Medicine
2,022
36,508,169
Prelacrimal Approach to Maxillary Sinus Pathology.
American journal of rhinology & allergy
Am J Rhinol Allergy
37
3
10.1177/19458924221144860
eng
2,023
5
null
2,022
12
12
[BACKGROUND] Access to the anterior, lateral, inferior, and inferomedial maxillary sinus has been a limitation of the middle meatal antrostomy. Expanded techniques such as the modified medial maxillectomy provide access to many of these areas but require remucosalization, and crusting can occur during the recovery phas...
endoscopic endonasal surgery; endoscopic nasal and sinus surgery; maxillary sinus neoplasms; paranasal sinus diseases; paranasal sinus neoplasms
null
null
null
null
null
36,507,598
Clinical practice guidelines on interventional management of low back pain: A synthesis of recommendations.
PM & R : the journal of injury, function, and rehabilitation
PM R
15
8
10.1002/pmrj.12930
eng
2,023
8
null
null
null
null
[OBJECTIVE] To summarize the recommendations on the interventional management of subacute and chronic nonradicular low back pain (LBP) from the 21 quality-appraised clinical practice guidelines (CPGs) identified in a previously published paper: "Quality of Clinical Practice Guidelines on Interventional Management of Lo...
null
null
null
null
null
null
36,507,484
Establishment of a formula for the estimation of kidney depth in adults and its effect on glomerular filtration rate assessment.
Translational andrology and urology
Transl Androl Urol
11
11
10.21037/tau-22-614
eng
2,022
11
null
null
null
null
[BACKGROUND] Gates' analysis method for kidney depth (KD) calculation is the only way to determine the glomerular filtration rate (GFR) of the kidney in clinical practice, which posits that the influence of KD on the GFR is more important than other factors. Computed tomography (CT) measurement of the donor KD can impr...
99mTc-DTPA renal dynamic imaging; Renal depth; glomerular filtration rate (GFR)
0.603
57
Reproductive Medicine; Urology
Medicine
2,022
36,507,134
Vacuum-assisted staged omphalocele reduction: A preliminary report.
Frontiers in pediatrics
Front Pediatr
10
null
10.3389/fped.2022.1053568
eng
2,022
null
null
2,022
11
24
[INTRODUCTION] Omphalocele represents a rare congenital abdominal wall defect. In giant omphalocele, due to the viscero-abdominal disproportion, gradual reintegration of eviscerated organs is often associated with medical challenges. We report our preliminary experience combining staged gravitational reduction with vac...
VAC; congenital abdominal wall defect; giant omphalocele; staged omphalocele reduction; vacuum therapy
0.798
83
Pediatrics, Perinatology and Child Health
Medicine
2,022
36,506,404
DWI-FLAIR mismatch guided thrombolysis in patients without large-vessel occlusion: real-world data from a comprehensive stroke centre.
Heliyon
Heliyon
8
12
10.1016/j.heliyon.2022.e12069
eng
2,022
12
null
2,022
12
5
[INTRODUCTION] A significant proportion of ischaemic stroke patients present with unknown symptom onset time. DWI-FLAIR mismatch on MRI can help to identify those eligible for thrombolysis. We set out to analyse the short-term efficacy and safety of thrombolysis in a real-world setting. [METHODS] A retrospective single...
Acute ischaemic stroke; Alteplase; DWI-FLAIR mismatch; Thrombolysis
0.609
115
Multidisciplinary
Multidisciplinary
2,022
36,505,791
ZNF24 regulates the progression of KRAS mutant lung adenocarcinoma by promoting SLC7A5 translation.
Frontiers in oncology
Front Oncol
12
null
10.3389/fonc.2022.1043177
eng
2,022
null
null
2,022
11
23
[BACKGROUND] Clinical treatment of RAS mutant cancers is challenging because of the complexity of the Ras signaling pathway. SLC7A5 is a newly discovered downstream gene of the Ras signaling pathway, but the regulatory mechanism is unclear. We aimed to explore the molecular mechanism and role in KRAS mutant lung adenoc...
KRAS mutation; SLC7A5; ZNF24; lung adenocarcinoma; protein interaction
1.138
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,505,668
Effectiveness of Smartphone-Based Lifestyle Interventions on Women with Gestational Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Psychology research and behavior management
Psychol Res Behav Manag
15
null
10.2147/PRBM.S389562
eng
2,022
null
null
2,022
12
5
[BACKGROUND] Gestational diabetes mellitus (GDM) is a condition that causes poor glucose tolerance during pregnancy and usually resolves after birth. Having GDM impacts the mother and baby. Smartphone-based lifestyle interventions may offer innovative solutions. [AIM] To examine the effects of smartphone-based lifestyl...
gestational diabetes mellitus; lifestyle interventions; meta-analysis; smartphone; systematic review; women
0.92
56
Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,022
36,505,617
Burden of diabetic foot syndrome in rural community: Need for screening and health promotion.
Journal of family medicine and primary care
J Family Med Prim Care
11
9
10.4103/jfmpc.jfmpc_1947_21
eng
2,022
9
null
2,022
10
14
[CONTEXT] Living with diabetes can be difficult since it can affect the patient in many ways. Diabetic foot syndrome (DFS) is described as a group of symptoms where neuropathy reduced blood supply and infection leads to tissue breakdown and morbidity. [AIM] This study aims to determine the prevalence of DFS and associa...
Diabetic foot syndrome; monofilament; peripheral neuropathy; rural areas; screening
null
null
null
null
null
36,505,379
Neurocognitive function in patients with atrial fibrillation undergoing pulmonary vein isolation.
Frontiers in cardiovascular medicine
Front Cardiovasc Med
9
null
10.3389/fcvm.2022.1000799
eng
2,022
null
null
2,022
11
25
[BACKGROUND] Atrial fibrillation (AF) is associated with cognitive dysfunction. However, neurocognitive function in AF patients undergoing pulmonary vein isolation (PVI) has not been well studied. The aim of this analysis is to compare neurocognitive function in patients who did or did not undergo PVI. [MATERIALS AND M...
Montreal Cognitive Assessment; atrial fibrillation; inverse probability of treatment weighting; neurocognitive function; propensity score; pulmonary vein isolation
1.391
81
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,505,372
Gender-based time discrepancy in diagnosis of coronary artery disease based on data analytics of electronic medical records.
Frontiers in cardiovascular medicine
Front Cardiovasc Med
9
null
10.3389/fcvm.2022.969325
eng
2,022
null
null
2,022
11
24
[BACKGROUND] Women continue to have worse Coronary Artery Disease (CAD) outcomes than men. The causes of this discrepancy have yet to be fully elucidated. The main objective of this study is to detect gender discrepancies in the diagnosis and treatment of CAD. [METHODS] We used data analytics to risk stratify ~32,000 p...
Coronary Artery Disease; big data; cardiac catheterization; coronary artery bypass grafting (CABG); electronic medical record; gender-based discrepancies
1.391
81
Cardiology and Cardiovascular Medicine
Medicine
2,022
36,505,305
Effects of PD-1 inhibitor combined with anti-angiogenic drugs on efficacy and immune function of non-small cell lung cancer.
American journal of translational research
Am J Transl Res
14
11
null
eng
2,022
null
null
2,022
11
15
[OBJECTIVE] To investigate the effect of PD-1 inhibitor combined with anti-angiogenic drugs on the therapeutic efficacy and immune function of patients with non-small cell lung cancer (NSCLC). [METHODS] Clinical data of 60 NSCLC patients who admitted to a regional Hospital of Traditional Chinese Medicine from May 2020 ...
PD-1 inhibitor; anti-angiogenic drugs; immunity; non-small cell lung cancer
null
null
null
null
null
36,505,286
MiR-216b targets CPEB4 to suppress colorectal cancer progression through inhibiting IL-10-mediated M2 polarization of tumor-associated macrophages.
American journal of translational research
Am J Transl Res
14
11
null
eng
2,022
null
null
2,022
11
15
[OBJECTIVES] The M2 polarization of tumor-associated macrophages (TAMs) facilitates the growth, invasion and metastasis of tumor cells. Here, we investigated the role of miR-216b in the M2 polarization of TAMs in colorectal cancer (CRC). [METHODS] The expression of genes were examined by quantitative real-time polymera...
CPEB4; Colorectal cancer; IL-10; M2 polarization; miR-216b; tumor-associated macrophages
null
null
null
null
null
36,505,236
Brevibacillus laterosporus BL1, a promising probiotic, prevents obesity and modulates gut microbiota in mice fed a high-fat diet.
Frontiers in nutrition
Front Nutr
9
null
10.3389/fnut.2022.1050025
eng
2,022
null
null
2,022
11
24
[SCOPE] Probiotics are a potential preventive strategy for obesity. However, with discrete efficacy and limited species of probiotics, there is a demand for novel strains with excellent anti-obesity properties. This study aimed to investigate the effects of Brevibacillus laterosporus BL1 on preventing obesity in high-f...
Brevibacillus laterosporus; gut microbiota; high-fat diet; lipid metabolism; obesity
0.875
94
Food Science; Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Agricultural and Biological Sciences; Medicine; Nursing
2,022
36,504,923
Association of Serum Vitamin D level and COVID-19 infection: A Case-control Study.
Qatar medical journal
Qatar Med J
2022
4
10.5339/qmj.2022.48
eng
2,022
null
null
2,022
12
5
[BACKGROUND] Vitamin D is considered a potent modulator of the immune system, albeit its role in COVID-19 infection is a matter of debate. The present study aimed to estimate the association between serum vitamin D levels and COVID-19 among people in Qatar. [METHODS] This case-control study, approved by the Institution...
COVID-19; Qatar; RT-PCR; SARS-CoV-2; Serum 25(OH)D; Vitamin D Deficiency
0.235
16
Medicine
Medicine
2,022
36,504,618
Medical students' attitudes and perceptions of influenza and SARS-CoV-2 vaccination in Cyprus.
Germs
Germs
12
2
10.18683/germs.2022.1321
eng
2,022
6
null
2,022
6
30
[INTRODUCTION] Infectious diseases constitute a significant problem globally and healthcare professionals (HCP) show suboptimal vaccination rates. We aimed to evaluate the determinants affecting vaccination against influenza and SARS-CoV-2 among medical students in Cyprus. [METHODS] We conducted a cross-sectional study...
COVID-19; SARS-CoV-2; influenza; medical students; prevention; vaccination
0.375
23
Epidemiology; Immunology and Microbiology; Infectious Diseases; Microbiology; Public Health, Environmental and Occupational Health
Immunology and Microbiology; Medicine
2,022
36,504,606
Clinical factors predictive of Gram-negative bloodstream infection at the Emergency Department.
Germs
Germs
12
2
10.18683/germs.2022.1325
eng
2,022
6
null
2,022
6
30
[INTRODUCTION] Bloodstream infection is a common condition at the Emergency Department (ED). Appropriate antibiotic therapy is also crucial for patients with bloodstream infection particularly at the ED. This study therefore aimed to find clinical factors predictive of types of bacterial pathogens in bloodstream infect...
Sepsis; fever; risk factor; sex
0.375
23
Epidemiology; Immunology and Microbiology; Infectious Diseases; Microbiology; Public Health, Environmental and Occupational Health
Immunology and Microbiology; Medicine
2,022
36,504,421
Sex-specific differences in T-cell immune dysregulation and aberrant response to inflammatory stimuli in offspring exposed to maternal chronic inflammation.
American journal of reproductive immunology (New York, N.Y. : 1989)
Am J Reprod Immunol
89
3
10.1111/aji.13665
eng
2,023
3
null
2,022
12
28
[PROBLEMS] Maternal chronic inflammation (MI) can adversely affect offspring's immune development resulting in dysregulation of splenic T cells. Interleukin 1 beta (IL-1β) contributes to mediating inflammation in the placenta to induce fetal toxicity and cause long-term postnatal sequelae. In this study, we investigate...
T-cell immunity development; Treg/Teff balance; maternal chronic inflammation
0.887
119
Obstetrics and Gynecology; Reproductive Medicine; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,023
36,504,349
Comparing vitamin B2 versus 5% dextrose in water for optimal ureteric jet visualisation at the time of pelvic reconstructive surgery: A randomised controlled trial.
BJOG : an international journal of obstetrics and gynaecology
BJOG
130
6
10.1111/1471-0528.17363
eng
2,023
5
null
2,023
1
5
[OBJECTIVE] To compare preoperative vitamin B2 versus intraoperative cystoscopy distension using 5% dextrose in water (D5W) for ureteric jet visualisation during pelvic reconstructive surgery. [DESIGN] Double-blinded, randomised controlled trial. [SETTING] Three tertiary hospitals in Toronto, Canada. [POPULATION] Adult...
cystoscopy; pelvic reconstructive surgery; randomised controlled trial; ureter patency; ureter visualisation
1.858
195
Obstetrics and Gynecology
Medicine
2,023
36,504,288
Surgery for subacromial impingement syndrome and occupational biomechanical risk factors in a 16-year prospective study among male construction workers.
Scandinavian journal of work, environment health
Scand J Work Environ Health
49
2
10.5271/sjweh.4075
eng
2,023
3
1
2,022
12
12
[OBJECTIVE] The aim of this study was to assess the association between occupational biomechanical exposures and the occurrence of surgical treatment for subacromial impingement syndrome (SIS). [METHODS] A cohort of 220 295 male constructions workers who participated in a national occupational health surveillance progr...
null
null
null
null
null
null
36,503,941
Intimate Female Partner Homicide Suicide: demographic and psychopathology aspects of perpetrators and a potential not yet classified diagnostic entityAnalyses of data taken from newspapers in Italy from 2009 to 2019.
Rivista di psichiatria
Riv Psichiatr
57
6
10.1708/3922.39073
eng
2,022
null
null
null
null
null
[INTRODUCTION] The homicide of the female partner followed by suicide of the perpetrator (Intimate Female Partner Homicide Suicide - IFPHS) has been a growing phenomenon over last years, but its psychosocial and psychopathological aspects have not been analyzed in-depth yet. [PURPOSE] The aim of this study was to inves...
null
null
null
null
null
null
36,503,814
Neurological prognostic factors for human herpes virus 6/7-associated acute encephalopathy in children: A single-center study.
Brain development
Brain Dev
45
2
10.1016/j.braindev.2022.10.005
eng
2,023
2
null
2,022
10
26
[AIM] To identify prognostic factors for severe neurological sequelae and epileptic seizures in children with human herpes virus (HHV) 6/7-associated acute encephalopathy (AE). [METHODS] We retrospectively studied pediatric cases of HHV6/7-associated AE between April 2011 and March 2021. Neurological sequelae were asse...
Acute encephalopathy; Coma; Epilepsy; Human herpes virus 6/7; Prognosis
null
null
null
null
null
36,503,497
Female sex workers and police violence during the Covid-19 health crisis in 2020-2021: results from the EPIC multi-country community-based research program in Argentina.
Harm reduction journal
Harm Reduct J
19
1
10.1186/s12954-022-00714-5
eng
2,022
12
12
2,022
12
12
[BACKGROUND] Female sex workers (FSW) have been disproportionately impacted by the Covid-19 crisis. Data show increases of police violence toward key populations (KP), likely a consequence of their role in enforcing health government measures. This study aimed to identify factors associated with police violence experie...
Argentina; Community-based organizations; Covid-19; Female sex worker; Police violence
1.414
71
Medicine; Psychiatry and Mental Health; Public Health, Environmental and Occupational Health
Medicine
2,022
36,503,483
Analysis of correlations between gut microbiota, stool short chain fatty acids, calprotectin and cardiometabolic risk factors in postmenopausal women with obesity: a cross-sectional study.
Journal of translational medicine
J Transl Med
20
1
10.1186/s12967-022-03801-0
eng
2,022
12
12
2,022
12
12
[BACKGROUND] Microbiota and its metabolites are known to regulate host metabolism. In cross-sectional study conducted in postmenopausal women we aimed to assess whether the microbiota, its metabolites and gut barrier integrity marker are correlated with cardiometabolic risk factors and if microbiota is different betwee...
Cardiometabolic risk; Menopause; Metabolism; Microbiota; Obesity; SCFA
1.544
153
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,022
36,503,200
Possibility of independent use of the yes/no Angoff and Hofstee methods for the standard setting of the Korean Medical Licensing Examination written test: a descriptive study.
Journal of educational evaluation for health professions
J Educ Eval Health Prof
19
null
10.3352/jeehp.2022.19.33
eng
2,022
null
null
2,022
12
12
[PURPOSE] This study aims to apply the yes/no Angoff and Hofstee methods to actual Korean Medical Licensing Examination (KMLE) 2022 written examination data to estimate cut scores for the written KMLE. [METHODS] Fourteen panelists gathered to derive the cut score of the 86th KMLE written examination data using the yes/...
Educational measurement; Humans; Physicians; Republic of Korea; Undergraduate medical education
0.917
25
Education; Health Professions
Health Professions; Social Sciences
2,022
36,502,809
Cesarean delivery rates based on time and indication using the Robson Ten-Group Classification System: Assessment at a Turkish tertiary center.
The journal of obstetrics and gynaecology research
J Obstet Gynaecol Res
49
3
10.1111/jog.15522
eng
2,023
3
null
2,022
12
11
[OBJECTIVE] This study aimed to evaluate increasing cesarean delivery (CD) rates, their causes, and changes over the years in a Turkish tertiary center using the Robson Ten-Group Classification System (RTGCS). [METHODS] Data of deliveries involving birth weight of ≥500 g or ≥24 weeks of gestation period from 2013 to 20...
Robson classification; cesarean delivery; cesarean rate; health systems
0.576
68
Medicine; Obstetrics and Gynecology
Medicine
2,023
36,502,656
A case of prune belly syndrome: Experience from a regional hospital in Togo.
International journal of surgery case reports
Int J Surg Case Rep
102
null
10.1016/j.ijscr.2022.107812
eng
2,023
1
null
2,022
11
29
[INTRODUCTION AND IMPORTANCE] Prune Belly syndrome is a rare congenital condition first reported in 1939. It is a malformative disease associated with high mortality. We report a neonatal case in a regional hospital in Togo. [PRESENTATION OF CASE] A 4-month-old male infant was brought to the hospital by his uncle becau...
Abdomen; Cryptorchidism; Hypoplasia; Prune belly; Syndrome; Togo
0.227
31
Surgery
Medicine
2,023
36,502,347
First year impacts of the COVID-19 pandemic on pediatric physiatrists.
Journal of pediatric rehabilitation medicine
J Pediatr Rehabil Med
15
4
10.3233/PRM-220012
eng
2,022
null
null
null
null
null
[PURPOSE] The objective of this study was to determine how the COVID-19 pandemic impacted the work and compensation of pediatric physiatrists during the first year of the pandemic. [METHODS] Pediatric physiatrists were surveyed in the spring of 2021 about how the first year of the COVID-19 pandemic impacted their pract...
COVID-19; Physiatry; pandemic; workforce
null
null
null
null
null
36,502,319
Clinical and Economic Assessment in Early-Stage Dementia by Severity and Amyloid-β Status: A 5-Year Retrospective Claims Study of GERAS-US Patients.
Journal of Alzheimer's disease : JAD
J Alzheimers Dis
91
2
10.3233/JAD-220415
eng
2,023
null
null
null
null
null
[BACKGROUND] The high burden of dementia and Alzheimer's disease (AD) increases substantially as disease progresses. Characterizing early patterns of health care utilization among patients who develop cognitive impairment may deepen our understanding of early disease trajectory and potentially facilitate timely diagnos...
Amyloid; burden of illness; comorbidity; dementia; economic burden; health care utilization; mild cognitive impairment
1.172
188
Clinical Psychology; Geriatrics and Gerontology; Medicine; Psychiatry and Mental Health; Neuroscience
Medicine; Neuroscience; Psychology
2,023