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40,420,187
Safety evaluation of baloxavir marboxil: analysis and discussion utilizing real adverse events from the FAERS database.
BMC pharmacology toxicology
BMC Pharmacol Toxicol
26
1
10.1186/s40360-025-00940-0
eng
2,025
5
26
2,025
5
26
[BACKGROUND] As a novel anti-influenza agent, baloxavir marboxil lacks real-world safety data in large populations. Therefore, this study aimed to investigate adverse drug events (ADEs) associated with baloxavir marboxil by analyzing the Food and Drug Administration Adverse Event Reporting System (FAERS) database. [MET...
Adverse drug reactions; Baloxavir marboxil; FAERS database; Influenza; Pharmacovigilance; Signal mining analysis
null
null
null
null
null
40,420,155
The lived experience of self-injury stigma and its psychosocial impact: a thematic analysis.
BMC psychology
BMC Psychol
13
1
10.1186/s40359-025-02664-6
eng
2,025
5
26
2,025
5
26
[BACKGROUND] Non-suicidal self-injury (NSSI) represents a prevalent and significant mental health difficulty experienced by young adults. Few efforts have explored lived experience perspectives concerning the impact of NSSI stigma, despite long-standing recognition that NSSI is highly stigmatised and recent calls for m...
Anticipated stigma; Enacted stigma; Lived experience; Nonsucidal self-injury; Public stigma; Qualitative; Self-harm; Self-stigma; Stigma
1.03
49
Medicine; Psychology
Medicine; Psychology
2,024
40,420,112
Prevalence of child abuse and common mental comorbidity among university of Khartoum medical students, Khartoum, Sudan.
BMC psychiatry
BMC Psychiatry
25
1
10.1186/s12888-025-07006-9
eng
2,025
5
26
2,025
5
26
[INTRODUCTION] Child abuse and neglect are significant public health issues worldwide, with severe and lasting effects on children's mental and physical well-being. Despite being prevalent in Sub-Saharan Africa, including Sudan, limited research has been conducted on this topic. This study investigates the prevalence o...
Child abuse; Medical students; Mental health; Sudan
1.375
151
Psychiatry and Mental Health
Medicine
2,024
40,420,086
A cross-sectional survey on the relationship between metacognitive ability and completion ability among Chinese nursing students: the mediating role of perceived campus atmosphere ability and the moderation of simulation teaching method.
BMC nursing
BMC Nurs
24
1
10.1186/s12912-025-03227-1
eng
2,025
5
26
2,025
5
26
[BACKGROUND] With the continuous development of medical technology, the demand for high-quality of nursing student training is increasing, and nursing, as an important part of health care service work, is facing new challenges. In recent years, the proportion of nursing undergraduates among registered nurses in China h...
Completion ability; Mediating role; Meta-cognition; Moderation; Nursing undergraduate; Perceived campus atmosphere ability
1.272
62
Nursing
Nursing
2,024
40,420,016
The mediating roles of anxiety, loneliness, stress, and depression in the relationship between cyberbullying and non-suicidal self-injury: propensity score matching and causal mediation analysis.
BMC psychiatry
BMC Psychiatry
25
1
10.1186/s12888-025-06943-9
eng
2,025
5
26
2,025
5
26
[BACKGROUND] Non-suicidal self-injury (NSSI) not only causes direct physical harm but also severely impacts mental health, increasing the risks of psychological disorders, behavioral issues, and suicidal tendencies. With the widespread use of the internet and electronic communication tools on smartphones, such as socia...
Causal mediation analysis; Cyberbullying; Non-suicidal self-injury; Psychological characteristics
1.375
151
Psychiatry and Mental Health
Medicine
2,024
40,419,851
The decay-accelerating factor (CD55) in acute leukemia patients and its query implication in cancer pathogenesis.
Journal of the Egyptian National Cancer Institute
J Egypt Natl Canc Inst
37
1
10.1186/s43046-025-00299-7
eng
2,025
5
27
2,025
5
27
[BACKGROUND] The role of the complement system and its membrane-bound regulatory proteins (mCRPs) in the pathogenesis of cancer is still a debatable issue. The current study aimed to evaluate the role of the complement regulatory protein, the decay-accelerating factor (CD55), in the pathogenesis of acute leukemia. [MET...
ALL; AML; CD55; Complement; DAF; MCRP; ShRNA
0.561
30
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,419,139
Reverse-normal immunopurification: An effective approach for purifying recombinant erythropoietin from its analogues in doping analysis.
Journal of sport and health science
J Sport Health Sci
14
null
10.1016/j.jshs.2025.101062
eng
2,025
5
24
2,025
5
24
[BACKGROUND] Recombinant erythropoietin (rEPO) is commonly used in therapy but may be abused in sports to enhance endurance. In doping analysis, rEPO can be detected in human urine or blood samples at picogram (pg) levels based on its slightly higher molecular weight (MW) than that of endogenous EPO using western blott...
Doping analysis; Erythropoietin; Immunopurification; Western blotting
3.197
76
Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation
Health Professions; Medicine
2,024
40,418,759
Applying an intersectional climate justice lens to understand climate crisis impacts on sexual and reproductive health and rights and identify local solutions: Qualitative findings from Khulna, Bangladesh.
Women's health (London, England)
Womens Health (Lond)
21
null
10.1177/17455057251339283
eng
2,025
null
null
2,025
5
26
[BACKGROUND] Climate change has been described as the greatest health threat of the 21st century. Increased evidence of the linkages between climate change and sexual and reproductive health and rights (SRHR) is essential to achieving full realization of SRHR. [OBJECTIVE] To understand if and how women and girls' perce...
adaptive capacity; climate change; climate justice; climate vulnerability; intersectionality; resilience; sexual and reproductive health and rights
0.963
56
Medicine
Medicine
2,024
40,418,516
3D multi-phase balanced non-steady-state free precession acquisition for multi-parameter mapping.
Magma (New York, N.Y.)
MAGMA
null
null
10.1007/s10334-025-01262-2
eng
2,025
5
26
2,025
5
26
[OBJECTIVE] This study presents the 3D MP-b-nSSFP sequence for multi-parametric mapping. [METHODS] We evaluate several aspects of the 3D implementation, like the type of RF pulse (selective/non-selective), the readout duration, the undersampling pattern, and the acceleration factor. We use undersampled scans with subsp...
Extended readout; SSFP; Subspace-constrained; Transient imaging; qMRI
null
null
null
null
null
40,418,396
Identification of metabolic biomarkers and therapeutic targets in the thymoma-associated myasthenia gravis treated with methylprednisolone.
Discover oncology
Discov Oncol
16
1
10.1007/s12672-025-02700-2
eng
2,025
5
26
2,025
5
26
[OBJECTIVE] This study aims to screen and identify metabolic biomarkers and targets for methylprednisolone treatment of thymoma with myasthenia gravis (MG) through metabolomics and network pharmacology analysis, thereby improving guidance for clinical medication and treatment. [METHODS] Serum from 15 patients with thym...
Metabolomics; Myasthenia gravis; Network pharmacology; Thymoma
0.88
47
Endocrine and Autonomic Systems; Endocrinology; Endocrinology, Diabetes and Metabolism; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
40,417,460
Relationship Between Leptin and Heart Failure: A Meta-Analysis.
Global heart
Glob Heart
20
1
10.5334/gh.1434
eng
2,025
null
null
2,025
5
23
[BACKGROUND] Heart failure (HF) is a diverse and potentially fatal condition affecting more than 60 million people worldwide. Previous studies have identified a close relationship between leptin levels and HF, and that leptin levels in patients with HF are higher than those in healthy individuals. However, some studies...
HF; heart failure; leptin
1.063
55
Cardiology and Cardiovascular Medicine; Community and Home Care; Epidemiology
Medicine; Nursing
2,024
40,417,406
Shortened length of stay and its impact on total shoulder arthroplasty expenses.
Shoulder elbow
Shoulder Elbow
null
null
10.1177/17585732251344159
eng
2,025
5
23
2,025
5
23
[BACKGROUND] The volume of both anatomic and reverse total shoulder arthroplasty (TSA) has increased in the United States over the last decade. A reduction in length of stay (LOS) postoperatively is a clear way to reduce hospital costs and labor burden. This study aimed to quantify how the LOS reduction has impacted in...
Total shoulder arthroplasty; administrative expense; hospital charge; hospital cost; inpatient TSA; length of stay; osteoarthritis; reduced LOS
null
null
null
null
null
40,417,143
Combined Posterior Vitrectomy and Ahmed Valve Implantation with Prior Antiangiogenic Application for the Management of Neovascular Glaucoma: A Case Series Study.
Journal of current glaucoma practice
J Curr Glaucoma Pract
19
1
10.5005/jp-journals-10078-1462
eng
2,025
null
null
2,025
3
24
[AIM AND BACKGROUND] This study aims to evaluate the institutional interdisciplinary management protocol for neovascular glaucoma patients, focusing on a combined surgical approach involving posterior vitrectomy and Ahmed valve implantation, with previous antiangiogenic application. [MATERIALS AND METHODS] A retrospect...
Ahmed valve; Anti-vascular endothelial growth factor; Antiglaucoma drugs; Intraocular pressure; Neovascular glaucoma; Pars plana vitrectomy
null
null
null
null
null
40,416,989
Bibliometric analysis and visualization of Connexin 43 in the field of solid tumor research(2000-2024).
Frontiers in immunology
Front Immunol
16
null
10.3389/fimmu.2025.1588828
eng
2,025
null
null
2,025
5
9
[BACKGROUND] Connexin 43 (Cx43) plays a pivotal role in tumor growth, metastasis, and disease progression. This study employs bibliometric analysis to identify key research trends and emerging hotspots in Cx43-related solid tumor research. [METHODS] In December 2024, the Web of Science Core Collection (WoSCC) database ...
Cx43; bibliometric analysis; immunity; phosphorylation; prognostic signature; resistance; solid tumor
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
40,416,836
Echocardiographic nomograms in children living at high altitude according to sex.
European heart journal. Imaging methods and practice
Eur Heart J Imaging Methods Pract
3
1
10.1093/ehjimp/qyaf053
eng
2,025
1
null
2,025
5
5
[AIMS] This study aimed to establish 2D and M-mode echocardiographic reference values for cardiac chambers, outflow tracts, and great vessels for school children living at high altitudes, differentiated between males and females. [METHODS AND RESULTS] This post hoc analysis included children with normal echocardiograph...
echocardiography; high altitude; nomogram; propensity score matching; reference value
null
null
null
null
null
40,416,799
Visual Research of Global Orphan Drug from a Bibliometric Perspective.
Drug design, development and therapy
Drug Des Devel Ther
19
null
10.2147/DDDT.S506112
eng
2,025
null
null
2,025
5
20
[OBJECTIVE] This study analyzes the current research landscape and trends in orphan drug development, providing insights for future advancements in the field. [METHODS] Gathering pertinent material from the China National Knowledge Infrastructure (CNKI) and Web of Science databases. Microsoft Office Excel 2017, VOSview...
bibliometrics; medication guarantee; orphan drug; orphan drug development; rare disease
1.19
108
Drug Discovery; Pharmaceutical Science; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,024
40,416,725
Rivaroxaban vs. enoxaparin for preventing venous thromboembolism after hip fracture operations: a retrospective cohort study.
Frontiers in surgery
Front Surg
12
null
10.3389/fsurg.2025.1483611
eng
2,025
null
null
2,025
5
9
[INTRODUCTION] Emerging evidence suggests that rivaroxaban may be effective in preventing venous thromboembolism (VTE) in patients with orthopedic trauma, resulting in fewer bleeding complications. This study aimed to evaluate the efficacy and safety of rivaroxaban compared with enoxaparin in preventing VTE in patients...
cost; enoxaparin; hip fractures; rivaroxaban; venous thromboembolism
0.541
48
Surgery
Medicine
2,024
40,416,566
Macrophage-Derived Exosomal MALAT1 Regulates Autophagy through miR-204-5p/ATG7 Axis in H9C2 Cardiomyocytes and Diabetic Rat Heart.
Acta Cardiologica Sinica
Acta Cardiol Sin
41
3
10.6515/ACS.202505_41(3).20250224D
eng
2,025
5
null
null
null
null
[BACKGROUND] Autophagy activity is tightly associated with cardiovascular disease development and progression. The effect of exosomal metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) derived from macrophages treated with high levels of glucose on autophagy in cardiomyocytes and diabetic hearts is not kno...
ATG7; Autophagy; Cardiomyocytes; Exosome; MALAT1; Macrophage
null
null
null
null
null
40,416,059
Advances in Targeted Therapy for Brain Metastases in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer: A Focus on ADCs and TKIs.
Breast cancer (Dove Medical Press)
Breast Cancer (Dove Med Press)
17
null
10.2147/BCTT.S503703
eng
2,025
null
null
2,025
5
19
[AIM] Brain metastasis remains a significant therapeutic challenge in HER2-positive breast cancer, contributing to poor prognosis and limited treatment options. This review aims to summarize recent advancements in targeted therapies for brain metastasis in HER2-positive breast cancer, with a focus on the efficacy, mech...
ADCs; HER2-positive; antibody-drug conjugates; breast cancer; human epidermal growth factor receptor 2-positive; targeted therapy
0.954
67
Medicine; Radiology, Nuclear Medicine and Imaging; Oncology; Pharmacology
Medicine
2,024
40,415,982
The Psychopathology of Problematic Smartphone Use (PSU): A Narrative Review of Burden, Mediating Factors, and Prevention.
Health science reports
Health Sci Rep
8
5
10.1002/hsr2.70843
eng
2,025
5
null
2,025
5
22
[BACKGROUND AND AIMS] Problematic smartphone use (PSU) has emerged as a growing public health concern, with increasing evidence linking it to mental health issues such as anxiety, depression, and sleep disturbances. While smartphones offer numerous benefits, excessive use can contribute to cognitive overload, emotional...
anxiety; depression; fear of missing out; insomnia; moderating factors; problematic smartphone use (PSU)
0.567
26
Medicine
Medicine
2,024
40,415,752
Comparative Evaluation of Shear Bond Strength of Fifth, Seventh, and Eighth-generation Bonding Agents in Permanent Teeth: An In Vitro Study.
International journal of clinical pediatric dentistry
Int J Clin Pediatr Dent
18
3
10.5005/jp-journals-10005-3096
eng
2,025
3
null
2,025
4
19
[AIMS AND BACKGROUND] In achieving clinical success with adhesive materials, bond strength holds significant importance. The goal of testing the strength of the bond is to establish a value for how strong the binding of an adhesive system is to the dental structures. The aim of this in vitro study is to comparatively e...
Acid etching; Adhesion; Bonding agent; Shear bond strength
0.381
18
Oral Surgery; Orthodontics; Periodontics; Pediatrics, Perinatology and Child Health
Dentistry; Medicine
2,024
40,415,733
Active Start Active Future: Feasibility of a Behaviour-Change Intervention to Reduce Sedentary Behaviour and Promote Physical Activity in Young Children with Cerebral Palsy.
Physical occupational therapy in pediatrics
Phys Occup Ther Pediatr
null
null
10.1080/01942638.2025.2506061
eng
2,025
5
26
2,025
5
26
[AIMS] Children with cerebral palsy (CP) have low physical activity (PA) and high sedentary behavior. The aim was to trial a participation-focused behavior-change intervention to increase PA and decrease sedentary behavior. [METHODS] Twelve children with CP were recruited (mean age 5 years 6 months ± 1 year 2 months, G...
Behavior change; cerebral palsy; feasibility study; participation-focused; physical activity; sedentary behavior
null
null
null
null
null
40,415,574
Full-Length Clonal Immunoglobulin Rearrangements in cfDNA: Improved Recovery and Sequencing.
Clinical chemistry
Clin Chem
71
8
10.1093/clinchem/hvaf064
eng
2,025
8
1
null
null
null
[BACKGROUND] Circulating tumor DNA present in cell-free DNA (cfDNA) serves as diagnostic, predictive, and prognostic markers in cancer patients. In lymphoma patients, clonal immunoglobulin (cIg) sequences enable accurate identification of disease states. Despite its importance, there is sparse literature surrounding th...
null
1.345
248
Biochemistry; Clinical Biochemistry; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,415,368
Nesfatin-1 Suppresses Inflammation in Bronchopulmonary Dysplasia by Regulating HMGB-1/TLR4/p65/NLRP3 Signaling Pathway.
Discovery medicine..
Discov Med
37
196
10.24976/Discov.Med.202537196.83
eng
2,025
5
null
null
null
null
[BACKGROUND] Bronchopulmonary dysplasia (BPD) is a common respiratory disease in premature infants. Nesfatin-1 is considered for the treatment of BPD. This study aimed to explore the anti-inflammatory effect of nesfatin-1 in the treatment of BPD. [METHODS] Hyperoxia-induced newborn rats and transfected primary type II ...
bronchopulmonary dysplasia; high mobility group box 1; inflammation; nesfatin-1
null
null
null
null
null
40,415,360
Mechanism Underlying Hyperbaric Oxygen's Effect on Nitric Oxide in an in Vitro Model of Traumatic Brain Injury.
Discovery medicine..
Discov Med
37
196
10.24976/Discov.Med.202537196.75
eng
2,025
5
null
null
null
null
[BACKGROUND] Hyperbaric oxygen (HBO) therapy functions as a possible therapeutic option for traumatic brain injury (TBI). The aim of this study is to detect the mechanism of HBO on TBI. [METHODS] Neurons and astrocytes isolated from healthy neonatal rat cortices were co-cultured, a TBI model was established, and cells ...
TNFR1; glutamate transporter-1; hyperbaric oxygen; nitric oxide; traumatic brain injury
null
null
null
null
null
40,415,215
Association between the serum uric acid-to-creatinine ratio and cardiovascular mortality in maintenance hemodialysis patients.
Renal failure
Ren Fail
47
1
10.1080/0886022X.2025.2509787
eng
2,025
12
null
2,025
5
25
[BACKGROUND] Uric acid is a risk factor for death in hemodialysis patients, but its exact role is still unclear. The serum uric acid-to-serum creatinine (SUA/SCr) ratio is a new indicator. This study aimed to clarify the relationship between this indicator and cardiovascular death in maintenance hemodialysis patients. ...
Hemodialysis; cardiovascular mortality; creatinine; uric acid
0.84
69
Nephrology; Critical Care and Intensive Care Medicine; Medicine
Medicine
2,024
40,414,825
Adjusted Global Antiphospholipid Syndrome Score Is Associated with End-Stage Kidney Disease in Patients with ANCA-Associated Vasculitis: A Single-Centre Pilot Study.
Yonsei medical journal
Yonsei Med J
66
6
10.3349/ymj.2024.0170
eng
2,025
6
null
null
null
null
[PURPOSE] The adjusted Global Antiphospholipid Syndrome (APS) Score (aGAPSS) was developed for assessing the probability of thrombotic events in APS patients. This study investigated whether the aGAPSS at diagnosis was associated with poor outcomes during follow-up in patients with antineutrophil cytoplasmic antibody (...
Adjusted Global Anti-Phospholipid Syndrome Score; antineutrophil cytoplasmic antibody; end-stage kidney disease; predict; vasculitis
0.827
78
Medicine
Medicine
2,024
40,414,762
The Mitochondrial Signature for Predicting Outcome of Early-Stage Breast Cancer by Machine Learning.
Clinical breast cancer
Clin Breast Cancer
null
null
10.1016/j.clbc.2025.04.020
eng
2,025
5
3
2,025
5
3
[INTRODUCTION] Breast cancer, a leading female cancer worldwide, can be influenced by mitochondrial dysfunction. Dysregulation of mitochondria by the nuclear genome may cause breast cancer initiation and progression. However, the comprehensive investigation of mitochondrial-related genes as prognostic marker for the ov...
Breast cancer; Early diagnosis; Nomogram; Prognosis; Transcriptome
1.018
85
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,414,458
Addressing Subgroup-Specific Treatment Effects to Avoid Inefficient Care: The Conflict Between Statistical and Health Economic Analyses.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
Value Health
28
8
10.1016/j.jval.2025.05.004
eng
2,025
8
null
2,025
5
23
[OBJECTIVES] When patients are classified into subgroups based on previously identified heterogeneity, this heterogeneity may affect the cost-effectiveness of health interventions. Whether this heterogeneity is reflected or ignored in cost-effectiveness analysis may influence reimbursement decisions. This is illustrate...
cost-effectiveness analyses; patient heterogeneity; simulation study
1.856
138
Health Policy; Medicine; Public Health, Environmental and Occupational Health
Medicine
2,024
40,414,344
Urinary proteins from stone formers promote calcium oxalate crystallization, growth and aggregation via oxidative modifications.
Journal of advanced research
J Adv Res
null
null
10.1016/j.jare.2025.05.040
eng
2,025
5
23
2,025
5
23
[INTRODUCTION] Various urinary parameters are used for determining kidney stone risk. However, almost all of the widely used lithogenic indices rely on urinary concentrations of small molecules/ions and pH. [OBJECTIVE] To address whether urinary macromolecules (especially oxidatively modified proteins) also play a crit...
Nephrolithiasis; Oxidized protein; Risk factor; Stone modulator; Urinary protein; Urolithiasis
2.576
108
Multidisciplinary
Multidisciplinary
2,024
40,414,261
Ensuring catheter-tissue contact with intracardiac echocardiography during pulsed-field ablation improves procedure outcome in patients with atrial fibrillation.
Heart rhythm
Heart Rhythm
null
null
10.1016/j.hrthm.2025.05.045
eng
2,025
5
23
2,025
5
23
[BACKGROUND] Catheter-tissue contact is critical in creating durable lesions during pulsed-field ablation (PFA) of atrial fibrillation (AF). [OBJECTIVE] This study aimed to compare the reconnection rate of previously ablated targets using PFA with vs without intracardiac echocardiography (ICE) guidance for confirmation...
Atrial fibrillation (AF); Intracardiac echocardiography (ICE); Pulsed-field ablation (PFA); Reconnection; Recurrence
1.929
165
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,024
40,414,138
Profiling gamers: The role of mental health, attachment and social factors in gaming behaviors.
Addictive behaviors
Addict Behav
169
null
10.1016/j.addbeh.2025.108390
eng
2,025
10
null
2,025
5
22
[BACKGROUND AND AIMS] This study examines the association of mental health, social and relational contexts, and gaming-related characteristics on the psychological profiles of video game players based on emotional regulation and motivations for gaming. [METHODS] A multinomial logistic regression analysis was conducted ...
Attachment; Gaming disorder; Mental health; Online; Profiles; Social
1.638
158
Clinical Psychology; Medicine; Psychiatry and Mental Health; Toxicology
Medicine; Pharmacology, Toxicology and Pharmaceutics; Psychology
2,024
40,413,916
Growth hormone regulates deiodinase type 2 and 3 expression via GATA.
Growth hormone IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
Growth Horm IGF Res
82
null
10.1016/j.ghir.2025.101659
eng
2,025
5
21
2,025
5
21
[OBJECTIVE] Growth hormone (GH) is involved in bone and skeletal muscle growth directly or indirectly via STAT5 and/or insulin-like growth factor (IGF)-1. Thyroid hormone (TH) is essential for general cellular growth and metabolic regulation. While both GH and TH are essential for growth, their actions may partially co...
Deiodinase; Growth hormone; Thyroid hormone
null
null
null
null
null
40,413,630
Immunization information systems' implementation and characteristics across the world: a systematic review of the literature.
Expert review of vaccines
Expert Rev Vaccines
24
1
10.1080/14760584.2025.2510338
eng
2,025
12
null
2,025
7
29
[INTRODUCTION] Immunization Information Systems (IISs) are essential public health tools, supporting the management and analysis of vaccination data to aid clinical and strategic decision-making. [METHODS] Following PRISMA guidelines, this systematic review investigated global state and operational characteristics of I...
Immunization information system; immunization program; mandatory vaccination; vaccination hesitancy; vaccines
1.255
112
Drug Discovery; Pharmacology; Immunology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Pharmacology, Toxicology and Pharmaceutics
2,024
40,413,619
Programmed death-ligand 1 tumor proportion score in predicting the safety and efficacy of PD-1/PD-L1 antibody-based therapy in patients with advanced non-small cell lung cancer: A retrospective, multicenter, observational study.
Chinese medical journal
Chin Med J (Engl)
138
14
10.1097/CM9.0000000000003620
eng
2,025
7
20
2,025
5
23
[BACKGROUND] This study aimed to investigate programmed death-ligand 1 tumor proportion score in predicting the safety and efficacy of PD-1/PD-L1 antibody-based therapy in treating patients with advanced non-small cell lung cancer (NSCLC) in a real-world setting. [METHODS] This retrospective, multicenter, observational...
Immune-related adverse events; Non-small cell lung cancer; Prognosis; Tumor proportional score
1.213
84
Medicine
Medicine
2,024
40,413,524
Impact of organ donation on grief symptoms in donor families.
BMC psychology
BMC Psychol
13
1
10.1186/s40359-025-02896-6
eng
2,025
5
24
2,025
5
24
[INTRODUCTION] The aim of the study was to identify the factors that influence grief among donor families regarding organ donation. [METHODS] This cross-sectional study, utilizing an analytical approach, employed a convenience sampling method to gather data from family members. Over the three years, all families who co...
Grief symptoms; Organ donation
1.03
49
Medicine; Psychology
Medicine; Psychology
2,024
40,413,522
Further characterization and engineering of an 11-amino acid motif for enhancing recombinant soluble protein expression.
Microbial cell factories
Microb Cell Fact
24
1
10.1186/s12934-025-02738-5
eng
2,025
5
24
2,025
5
24
[BACKGROUND] Escherichia coli (E. coli) is a popular system for recombinant protein production, owing to its low cost and availability of genetic tools. However, the expression of soluble recombinant proteins remains an issue. As such, various solubility-enhancing and yield-improving methods such as the addition of fus...
Escherichia coli; Enzyme; Growth factor; Protein solubility tag; Recombinant protein expression
1.103
134
Applied Microbiology and Biotechnology; Bioengineering; Biotechnology
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Immunology and Microbiology
2,024
40,413,498
Prevalence of eating disorders in aquatic athletes: a systematic review and meta-analysis.
Annals of general psychiatry
Ann Gen Psychiatry
24
1
10.1186/s12991-025-00564-y
eng
2,025
5
24
2,025
5
24
[BACKGROUND] Aquatic athletes may face unique pressures related to body aesthetics and weight management, potentially increasing their risk of eating disorders (EDs). This systematic review and meta-analysis aimed to estimate the prevalence of EDs in aquatic athletes and assess the quality of the available evidence. [M...
Aquatic athletes; Athlete mental health; Disordered eating; Eating disorders; Sports psychology
1.465
62
Psychiatry and Mental Health
Medicine
2,024
40,413,451
Distribution of CCR5-Delta32, CCR2-64I, and SDF1-3'A host genetic factors in HIV-infected and uninfected individuals in Luanda, Angola.
AIDS research and therapy
AIDS Res Ther
22
1
10.1186/s12981-025-00751-7
eng
2,025
5
24
2,025
5
24
[BACKGROUND] The HIV/AIDS pandemic remains a public health concern. Studies on host genetic polymorphisms that confer resistance to HIV-1 infection or delay HIV disease progression are scarce in African countries. Herein, we investigate the proportion of the mutated phenotype of the AIDS-related polymorphisms CCR5-Delt...
AIDS-related gene variants; Allelic frequency; Angola; HIV
0.943
51
Molecular Medicine; Pharmacology; Virology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,024
40,413,425
Comparison between transtracheal and intravenous 2% lignocaine in attenuating hemodynamic stress response following direct laryngoscopy and endotracheal intubation: a randomized controlled trial.
BMC anesthesiology
BMC Anesthesiol
25
1
10.1186/s12871-025-03102-1
eng
2,025
5
24
2,025
5
24
[BACKGROUND AND AIMS] Lignocaine is used through various routes to mitigate the hemodynamic surge associated with laryngoscopy and endotracheal intubation during general anesthesia. This study hypothesized that post-induction administration of transtracheal 2% lignocaine at 1.5 mg/kg would have a similar effect to intr...
Hemodynamics; Tracheal Intubation; Transtracheal Injection
0.753
58
Anesthesiology and Pain Medicine
Medicine
2,024
40,413,416
The impact of nuchal ligament ossification resection on cervical stability after modified laminoplasty: a long-term follow-up study.
BMC musculoskeletal disorders
BMC Musculoskelet Disord
26
1
10.1186/s12891-025-08729-2
eng
2,025
5
24
2,025
5
24
[STUDY DESIGN] A retrospective study. [OBJECTIVES] This study aims to investigate the relationship between the resection of ossification of the nuchal ligament (ONL), its morphological features, and cervical stability following modified laminoplasty. [METHODS] We retrospectively reviewed the data of patients diagnosed ...
Cervical stability; Degenerative cervical myelopathy (DCM); Laminoplasty; Muscle-ligament complex (MLC); Ossification of the nuchal ligament (ONL)
0.805
131
Orthopedics and Sports Medicine; Rheumatology
Medicine
2,024
40,412,628
The efficacy and safety of dapagliflozin in pediatric heart failure.
International journal of cardiology
Int J Cardiol
435
null
10.1016/j.ijcard.2025.133384
eng
2,025
9
15
2,025
5
22
[BACKGROUND] SGLT2 inhibitors (SGLT2i) have consolidated their position as first-line therapeutic agents in adult heart failure. However, there is minimal data on pediatric population. We conducted an observational study to evaluate efficacy and safety of Dapagliflozin in pediatric heart failure. [METHODS] Patients les...
Dapagliflozin; Dilated cardiomyopathy; Heart failure; Pediatrics; Sodium-glucose cotransporter 2 inhibitors
1.132
155
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,412,604
Right atrial cardioneuroablation of asystolic reflex syncope.
Heart rhythm
Heart Rhythm
null
null
10.1016/j.hrthm.2025.05.038
eng
2,025
5
22
2,025
5
22
[BACKGROUND] Cardioneuroablation (CNA) should focus on the vagal ganglia located in the right atrium close to the sinoatrial and the atrioventricular nodes. [OBJECTIVE] The study aimed to evaluate the efficacy and safety of right atrial CNA. [METHODS] Patients with severe, asystolic reflex syncope identified by implant...
AV node; Asystole; Catheter ablation; Implantable loop recorder; Neurally-mediated syncope; Reflex syncope; Sinoatrial node; Syncope; Tilt testing
1.929
165
Cardiology and Cardiovascular Medicine; Physiology
Medicine
2,024
40,412,484
Combining Radiation Therapy With Immune Checkpoint Inhibitors for the Management of Muscle-Invasive Bladder Cancer: A Comprehensive Systematic Review From the Y-ECI ROSC EORTC Group.
Practical radiation oncology
Pract Radiat Oncol
null
null
10.1016/j.prro.2025.05.004
eng
2,025
5
22
2,025
5
22
[PURPOSE] This review aims to evaluate the efficacy and safety of combining immune checkpoint inhibitors (ICI) with RT in the treatment of non-metastatic MIBC, focusing on neoadjuvant and bladder preservation strategies. [METHODS AND MATERIALS] A systematic literature review was conducted from January 2000 to December ...
null
1.011
57
Radiology, Nuclear Medicine and Imaging; Oncology
Medicine
2,024
40,412,238
Opportunities to improve mentorship of underrepresented minority nurse faculty on the tenure track: A Delphi study.
Nursing outlook
Nurs Outlook
73
4
10.1016/j.outlook.2025.102437
eng
2,025
null
null
2,025
5
23
[BACKGROUND] Mentorship is essential for supporting doctorally prepared nurses transitioning into academic roles and for addressing the escalating nurse faculty shortage. [PURPOSE] The objective of this study was to gain consensus on barriers, facilitators, and metrics of successful mentorship of doctorally prepared un...
Mentorship; Nurse faculty; URM; Underrepresented minority
1.195
76
Nursing
Nursing
2,024
40,412,012
Robot-assisted liver surgery reduces complication rates while maintaining equivalent outcome quality compared to open liver surgery.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Eur J Surg Oncol
51
9
10.1016/j.ejso.2025.110167
eng
2,025
5
16
2,025
5
16
[INTRODUCTION] Resecting liver surgery has been dominated by open surgical approaches (OLR). Minimal invasive procedures such as robotic liver surgery (RLR) are technically challenging but may reduce the surgical trauma and complication rates. [OBJECTIVES AND METHODS] This study aims to compare the outcomes of RLR and ...
Hepatobiliary surgery; Minimal invasive liver surgery; Oncologic surgery; Robotic liver surgery
1.153
123
Medicine; Surgery; Oncology
Medicine
2,024
40,411,933
Intrinsic foot muscles size and quality changes after impairment-based rehabilitation in patients with chronic ankle instability.
Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine
Phys Ther Sport
74
null
10.1016/j.ptsp.2025.05.008
eng
2,025
7
null
2,025
5
17
[OBJECTIVE] To determine IFMs size and quality using US imaging following rehabilitation in patients with CAI. [DESIGN] Prospective cohort study. [SETTINGS] University Laboratory. [PARTICIPANTS] 26 patients with CAI (age:21.9 ± 3.5 yrs; 18F, 8M) completed 8 clinician-supervised rehabilitation sessions over a 4-week per...
Ankle instability; Echogenicity; Foot core; Postural control
1.002
66
Medicine; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,024
40,411,775
A combined prospective and retrospective comparative study evaluating renal outcomes after switching from TDF + FTC + EFV to TDF/3TC/DTG (TLD) vs. DTG + 3TC in virologically suppressed Thai people with HIV.
HIV research clinical practice
HIV Res Clin Pract
26
1
10.1080/25787489.2025.2509379
eng
2,025
12
null
2,025
5
24
[BACKGROUND] TDF/3TC/DTG (TLD) has been adopted as the first-line therapy for all people with HIV according to the WHO 2019 and Thai HIV guidelines. As a result, people with HIV in Thailand on TDF/FTC/EFV are switched to TLD. However, increasing data demonstrate the efficacy and renal safety of the TDF-sparing dual the...
Dolutegravir; TLD regimen; dual therapy; renal outcomes; switch
null
null
null
null
null
40,411,760
Mitral valve surgery after failed transcatheter intervention for mitral regurgitation: surgical techniques, challenges and outcomes.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Eur J Cardiothorac Surg
67
6
10.1093/ejcts/ezaf179
eng
2,025
6
3
null
null
null
[OBJECTIVES] This review article aims to examine the surgical approach to patients with failed mitral transcatheter edge-to-edge repair (M-TEER), focusing on operative challenges, decision-making and contemporary outcome data. Technical considerations, including device removal and the management of complex mitral valve...
Mitral regurgitation; Mitral transcatheter edge-to-edge repair; Mitral valve repair; Mitral valve replacement
1.033
158
Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,024
40,411,696
CD155 as a prognostic and predictive biomarker in acute myeloid leukemia.
Discover oncology
Discov Oncol
16
1
10.1007/s12672-025-02665-2
eng
2,025
5
24
2,025
5
24
[BACKGROUND] Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy with different molecular and genetic alterations. CD155 is expressed on myeloid cells and serves as a recognition molecule for natural killer (NK) cells to induce cytotoxicity. This study aimed to assess the prognostic and predictive ...
Acute Myeloid Leukemia; CD155; Survival
0.88
47
Endocrine and Autonomic Systems; Endocrinology; Endocrinology, Diabetes and Metabolism; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
40,411,478
Is It Feasible to Screen for Fetal De Novo or Paternally Inherited Pathogenic Single Nucleotide Variants in Maternal Plasma Cell-Free DNA? A Systematic Literature Review.
Prenatal diagnosis
Prenat Diagn
45
9
10.1002/pd.6822
eng
2,025
8
null
2,025
5
24
[OBJECTIVE] Monogenic disorders (MDs), often associated with developmental delay, intellectual disability, hypotonia, or dysmorphic facial features, typically go undetected during pregnancy. These disorders are frequently caused by de novo single nucleotide variants (SNVs), which are not currently covered by routine no...
maternal plasma; monogenic disorders; noninvasive prenatal testing; paternal inheritance; prenatal screening; single nucleotide polymorphism
0.932
110
Obstetrics and Gynecology; Genetics
Medicine
2,024
40,411,337
Knowledge of HIV status among men aged 20-35 years in Lusaka, Zambia: Findings from a pilot time location sampling survey in the "Yaba Guy Che" (for the guys) study.
Tropical medicine international health : TM IH
Trop Med Int Health
30
7
10.1111/tmi.14128
eng
2,025
7
null
2,025
5
24
[OBJECTIVES] We conducted a pilot time location sampling survey with young men aged 20-35 years in Lusaka, Zambia and aimed to describe knowledge of HIV status and determine factors associated with knowledge of HIV status. [METHODS] Hotspots where men congregate were identified in a densely populated community in Lusak...
HIV testing; Zambia; feasibility; men; time location sampling
null
null
null
null
null
40,410,733
Phenotypes of successful living among adolescents with HIV in Rwanda: a latent profile analysis.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-23138-9
eng
2,025
5
23
2,025
5
23
[BACKGROUND] HIV remains a major public health concern globally, and 85% of adolescents with HIV (AWH) live in Sub-Saharan Africa (SSA). Despite advances in treatment and prevention efforts, adolescents continue to be disproportionately affected by HIV and are a group with poor adherence to antiretroviral medication. W...
Adolescent; HIV; Latent profile analysis; Phenotypes; Successful living
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,410,331
Imaging in staging, treatment planning, and monitoring of hepatocellular carcinoma for local and locoregional therapies: consensus recommendations from EORTC and ESGAR.
European radiology
Eur Radiol
null
null
10.1007/s00330-025-11699-7
eng
2,025
5
23
2,025
5
23
[BACKGROUND] Periinterventional imaging of patients with hepatocellular carcinoma (HCC) during local and locoregional therapies plays a crucial role in clinical outcome by guiding treatment allocation, planning, and application. However, there is a considerable variety in clinical routine in terms of timing, modality, ...
Ablation; Hepatocellular carcinoma; Imaging; SBRT; TACE
1.535
182
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,410,031
Effects of COVID-19-Associated Pulmonary Aspergillosis (CAPA) on the prognosis of severe COVID-19: Clinical characteristics and risk factors in a second-level hospital from Southern Spain.
Enfermedades infecciosas y microbiologia clinica (English ed.)
Enferm Infecc Microbiol Clin (Engl Ed)
null
null
10.1016/j.eimce.2025.05.004
eng
2,025
5
22
2,025
5
22
[INTRODUCTION] SARS-CoV-2 infection patients face infectious complications, including fungal infections. COVID-19-Associated Pulmonary Aspergillosis (CAPA) is linked to SARS-CoV-2 damage, corticosteroids, and pulmonary diseases. Diagnostic uncertainties persist, and this study aims to contribute evidence on CAPA risk f...
Aspergillosis; Aspergilosis; COVID-19; Critical care; Cuidados intensivos; Immunosuppression
0.337
49
Infectious Diseases; Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,024
40,409,764
Deep learning-based automatic differentiation of acute angle closure with or without zonulopathy using ultrasound biomicroscopy: a comparison of diagnostic performance with ophthalmologists.
BMJ open ophthalmology
BMJ Open Ophthalmol
10
1
10.1136/bmjophth-2024-002114
eng
2,025
5
22
2,025
5
22
[OBJECTIVE] This study aims to develop ultrasound biomicroscopy (UBM)-based artificial intelligence (AI) models for preoperative differentiation of acute angle closure (AAC) with or without zonulopathy and to compare their comprehensive diagnostic performance against ophthalmologists as a cross-sectional study. [METHOD...
Angle; Anterior chamber; Glaucoma
0.908
28
Ophthalmology
Medicine
2,024
40,409,580
Evaluation of a web app-based music intervention on pain during wound closure in the emergency department: The EMERGENCE randomized controlled trial.
Anaesthesia, critical care pain medicine
Anaesth Crit Care Pain Med
44
4
10.1016/j.accpm.2025.101545
eng
2,025
8
null
2,025
5
21
[BACKGROUND] Wound suturing in emergency departments is a potentially stressful and painful experience for patients. Web app-based music intervention is known as an effective adjuvant treatment for the management of physical pain and anxiety in various medical fields. Only two studies have assessed the effectiveness of...
Anxiety; Emergency; Music care; Musicotherapy; Pain; Wound closure
null
null
null
null
null
40,409,468
Vitamin D3 and marine ω-3 fatty acids supplementation and leukocyte telomere length: 4-year findings from the VITamin D and OmegA-3 TriaL (VITAL) randomized controlled trial.
The American journal of clinical nutrition
Am J Clin Nutr
122
1
10.1016/j.ajcnut.2025.05.003
eng
2,025
7
null
2,025
5
21
[BACKGROUND] Limited studies suggest that vitamin D or omega 3 fatty acids (n-3 FAs) supplementation may be beneficial for telomere maintenance, however, evidence from large randomized clinical trial is lacking. [OBJECTIVE] We aimed to determine whether vitamin D or n-3 FAs supplementation reduce leukocyte telomere len...
aging; telomere length; vitamin D
2.111
390
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
40,409,365
Impact of clinical target volume utilization on outcomes in patients with non-spine bone oligometastases treated with stereotactic ablative radiation therapy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Radiother Oncol
209
null
10.1016/j.radonc.2025.110948
eng
2,025
8
null
2,025
5
21
[PURPOSE] To compare local failure, marginal failure, and toxicity in non-spine bone metastases (NSBMs) treated with versus without a CTV for stereotactic ablative radiotherapy (SABR). [METHODS] The study included all patients in British Columbia treated with SABR for NSBMs on the SABR-5 trial (November 2016 - July 202...
Clinical Target Volume; Non-Spine Bone Metastases; Stereotactic Ablative Body Radiotherapy
1.738
189
Hematology; Oncology; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,409,174
"Salvage surgery for vestibular schwannomas after failed stereotactic radiosurgery or radiation: A systematic review and meta-analysis".
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
J Clin Neurosci
137
null
10.1016/j.jocn.2025.111330
eng
2,025
7
null
2,025
5
22
[INTRODUCTION] Stereotactic radiosurgery effectively controls vestibular schwannoma (VS). However, in certain cases, microsurgical resection may be necessary for tumor progression after radiosurgery or, after failure of the latter. The results on the safety and efficacy of salvage surgery for VS are still unclear, with...
Radiotherapy; Salvage Surgery; Stereotactic Radiosurgery; Vestibular Schwannomas
0.654
104
Medicine; Surgery; Neurology; Neurology; Physiology
Medicine; Neuroscience
2,024
40,409,064
Acculturative stress, body image ideals, body dissatisfaction, and eating pathology among Black, Asian, and Latina women.
Eating behaviors
Eat Behav
57
null
10.1016/j.eatbeh.2025.101992
eng
2,025
4
null
2,025
5
17
[BACKGROUND] Research supports the relation between acculturative stress and eating pathology across racially and ethnically diverse groups of women. However, relatively few studies have examined mechanisms of this link. The current study addressed these gaps by examining the potential roles of thin-, muscular-, and ho...
Acculturative stress; Body dissatisfaction; Body image ideal-internalization; Eating pathology
0.908
91
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
40,408,783
Anaphase promoting complex subunit 10 is a potential diagnostic and prognostic biomarker in oral squamous cell carcinoma.
Archives of oral biology
Arch Oral Biol
176
null
10.1016/j.archoralbio.2025.106296
eng
2,025
8
null
2,025
5
15
[OBJECTIVE] To explore the role of anaphase promoting complex subunit 10 (ANAPC10) in both the diagnosis and prognosis of oral squamous cell carcinoma (OSCC). [DESIGN] ANAPC10 expressions in OSCC tissues and adjacent normal tissues were analysed using TCGA and GEO databases. Its clinical prognostic significance was eva...
Anaphase promoting complex subunit 10; Cell cycle; Immune infiltration; Oral squamous cell carcinoma; RNA splicing
0.63
109
Dentistry; Medicine; Otorhinolaryngology; Cell Biology
Biochemistry, Genetics and Molecular Biology; Dentistry; Medicine
2,024
40,408,167
Sedative-hypnotics are associated with additional risk of suicide in older adults: a population-based case-control study.
Sleep
Sleep
null
null
10.1093/sleep/zsaf136
eng
2,025
5
23
2,025
5
23
[STUDY OBJECTIVES] To examine the pattern of sedative-hypnotic prescriptions associated with the risk of suicide behavior among older adults with and without insomnia. [METHODS] The study included 8 319 suicide cases and age- and sex-matched controls from the population-wide National Health Insurance Research Database....
Z-drugs; benzodiazepines; depression; sleep; violent means
1.796
248
Behavioral Neuroscience; Clinical Psychology; Neurology; Neuropsychology and Physiological Psychology; Physiology
Medicine; Neuroscience; Psychology
2,024
40,408,104
Dynamic Computed Tomography Findings as Indicators of Uterine Artery Embolization in Postpartum Hemorrhage.
JAMA network open
JAMA Netw Open
8
5
10.1001/jamanetworkopen.2025.12209
eng
2,025
5
1
2,025
5
1
[IMPORTANCE] Postpartum hemorrhage (PPH) remains the leading cause of maternal mortality globally. Although traditional management relies on blood loss quantification, identifying cases resistant to conventional treatment remains challenging, potentially delaying crucial interventions. [OBJECTIVE] To determine the prev...
null
3.546
154
Medicine
Medicine
2,024
40,407,949
Impact of surgical approach on complications by sex following ventral and incisional hernia repair.
Hernia : the journal of hernias and abdominal wall surgery
Hernia
29
1
10.1007/s10029-025-03371-2
eng
2,025
5
23
2,025
5
23
[PURPOSE] Female patients are more likely than male patients to experience postoperative complications following hernia repair, but the drivers of this phenomenon remain unexplored. Whether surgical approach differentially impacts the likelihood of postoperative complications by sex following ventral and incisional her...
Hernia care; Outcomes; Sex-based inequity; Ventral and incisional hernia repair
1.102
89
Surgery
Medicine
2,024
40,407,934
Factors Influencing the Efficacy and Safety of Monoclonal Antibody Biologics in Chronic Obstructive Pulmonary Disease: A Meta-analysis of Randomized Controlled Trials.
Lung
Lung
203
1
10.1007/s00408-025-00795-6
eng
2,025
3
14
2,025
3
14
[BACKGROUND] Monoclonal antibody therapies targeting specific inflammatory pathways have shown potential in treating chronic obstructive pulmonary disease (COPD). However, the efficacy and safety of these treatments across different patient phenotypes remain uncertain. [METHODS] This meta-analysis included 15 registere...
COPD; Exacerbation; Meta-analysis; Monoclonal antibodies
1.007
74
Pulmonary and Respiratory Medicine
Medicine
2,024
40,407,922
Is Akin fixation necessary in the Percutaneous Chevron and Akin osteotomies (PECA) technique? A retrospective comparative study with 2-year follow-up.
European journal of orthopaedic surgery traumatology : orthopedie traumatologie
Eur J Orthop Surg Traumatol
35
1
10.1007/s00590-025-04316-2
eng
2,025
5
23
2,025
5
23
[BACKGROUND] Minimally invasive or percutaneous techniques for correcting hallux valgus (HV) have been increasingly prominent in scientific publications. However, the Akin osteotomy has received little attention. The aim of this study was to evaluate whether there is a difference between fixation or non-fixation of the...
AOFAS; Akin osteotomy; Chevron osteotomy; Forefoot surgery; Hallux valgus; Minimally invasive surgery; PECA; Percutaneous surgery
null
null
null
null
null
40,407,861
A cost-effectiveness analysis comparing single-inhaler extrafine beclomethasone/formoterol/glycopyrronium bromide against other SITTs in adult patients with uncontrolled asthma in England.
Health economics review
Health Econ Rev
15
1
10.1186/s13561-025-00640-9
eng
2,025
5
23
2,025
5
23
[BACKGROUND] In patients with asthma uncontrolled by a medium or high-strength (MS/HS) inhaled corticosteroid (ICS) plus long-acting β2-agonist (LABA), according to Global Initiative for Asthma (GINA) guidelines, a maintenance therapy option is the addition of a long-acting muscarinic antagonist (LAMA) via single-inhal...
Asthma; Cost-effectiveness; England; Exacerbations; Network meta-analysis; Single-inhaler triple therapy
0.915
41
Health Policy
Medicine
2,024
40,407,845
Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) study: a seven- and twelve-year prospective analysis of occupational exposures and health outcomes among police officers.
International archives of occupational and environmental health
Int Arch Occup Environ Health
98
4-5
10.1007/s00420-025-02142-x
eng
2,025
7
null
2,025
5
23
[OBJECTIVE] Overall, police officers have higher rates of several adverse health conditions (e.g., cardiovascular health profiles and post-traumatic stress disorder (PTSD)) compared to persons in many other occupations. Our objective was to conduct a comparative study of occupational exposures and health outcomes among...
Cardiovascular disease; Depression; Health; PTSD; Police officers; Stress
1.051
105
Public Health, Environmental and Occupational Health
Medicine
2,024
40,407,639
Effectiveness of a multimodal physiotherapy program in fighter pilots with flight-related neck pain: A randomized controlled trial.
PM R : the journal of injury, function, and rehabilitation
PM R
null
null
10.1002/pmrj.13399
eng
2,025
5
23
2,025
5
23
[BACKGROUND] Flight-related neck pain constitutes a clinical entity related to the performance, occupational health, and flight safety of fighter pilots. [OBJECTIVE] To investigate whether a multimodal physiotherapy program combining supervised motor control exercises with laser-guided feedback and interferential curre...
null
null
null
null
null
null
40,406,936
Prenatal Diagnosis of Foetal Structural Anomalies Using Medium-Coverage Whole Genome Sequencing (CMA-Seq): A Large-Scale Comparative Study With CMA in 3973 Pregnancies.
BJOG : an international journal of obstetrics and gynaecology
BJOG
132
10
10.1111/1471-0528.18222
eng
2,025
9
null
2,025
5
23
[OBJECTIVE] To evaluate the feasibility and effectiveness of medium-coverage whole genome sequencing (CMA-seq) for prenatal diagnosis of foetal structural anomalies, and to compare its performance with conventional chromosomal microarray analysis (CMA). [DESIGN] A prospective clinical study combined with a systematic m...
chromosomal abnormalities; foetal structural anomalies; prenatal diagnosis; whole genome sequencing
1.786
195
Obstetrics and Gynecology
Medicine
2,024
40,406,542
Vancomycin dosing in neonates: enhancing outcomes using population pharmacokinetics and simulation.
Frontiers in antibiotics
Front Antibiot
4
null
10.3389/frabi.2025.1568931
eng
2,025
null
null
2,025
5
8
[INTRODUCTION] Optimizing vancomycin dosing in neonates is a critical yet complex goal. Traditional trough concentration-based dosing strategies correlate poorly with therapeutic efficacy and often fail to account for the significant renal function variability and drug clearance in neonates. The 24-hour area under the ...
dosing regimens; neonatology; population pharmacokinetics; simulations; the probability of target attainment; vancomycin
null
null
null
null
null
40,406,134
Development and validation of an ARID1A-related immune genes risk model in evaluating prognosis and immune therapeutic efficacy for gastric cancer patients: a translational study.
Frontiers in immunology
Front Immunol
16
null
10.3389/fimmu.2025.1541491
eng
2,025
null
null
2,025
4
28
[BACKGROUND] Mutations in the ARID1A gene, an integral component of the SWI/SNF complex, are prevalent, affecting prognosis and immune response in several malignancies, including gastric cancer (GC). The aim of this study was to identify ARID1A mutation-associated immune genes to construct an ARID1A-related immune gene...
ARID1A; gastric cancer; immune gene risk model; molecular docking; prognosis
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
40,405,976
Identification and validation of immune-related and inflammation-related genes in endometriosis.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
16
null
10.3389/fendo.2025.1545670
eng
2,025
null
null
2,025
5
8
[AIM] Endometriosis is characterized by immune evasion and progressive inflammation. This study aimed to identify key genes related to immune and inflammation in endometriosis. [METHODS] Differentially expressed genes between patients with and without endometriosis were identified from the GEO database. Furthermore, im...
biomarker; endometriosis; immunity; inflammation; machine learning
1.472
138
Endocrinology, Diabetes and Metabolism
Medicine
2,024
40,405,962
Correlation study of tumor-infiltrating lymphocytes (TILs) and subtypes analysis before and after neoadjuvant chemotherapy in triple-negative breast cancer.
Gland surgery
Gland Surg
14
4
10.21037/gs-2024-537
eng
2,025
4
30
2,025
4
17
[BACKGROUND] In recent years, neoadjuvant chemotherapy (NACT) has become an increasingly important treatment for triple-negative breast cancer (TNBC). As the most immunogenic subtype of breast cancer, it is imperative to comprehensively study the immune microenvironment of TNBC and the effects of NACT on it. Our study ...
Triple-negative breast cancer (TNBC); immune cell subset; neoadjuvant chemotherapy (NACT); programmed cell death ligand 1 (PD-L1); tumor-infiltrating lymphocytes (TILs)
0.492
43
Surgery
Medicine
2,024
40,405,718
Navigating Cultural Stress and Mental Health: A Longitudinal Study of Parent-Adolescent Dynamics Among Former Soviet Union Families.
Journal of adolescence
J Adolesc
97
6
10.1002/jad.12522
eng
2,025
8
null
2,025
5
23
[INTRODUCTION] Cultural stressors during migration can shape family dynamics and impact mental health outcomes. This study investigates the relationship between cultural stress, parent-adolescent communication, and psychological well-being among Former Soviet Union (FSU) immigrant families in Israel. [METHODS] This lon...
Former Soviet Union; cultural stress; mental health
1.506
145
Developmental and Educational Psychology; Pediatrics, Perinatology and Child Health; Psychiatry and Mental Health; Social Psychology
Medicine; Psychology
2,024
40,450,559
Understanding affiliate stigma among significant others of adults with hearing loss: a cross-sectional survey in Australia, the UK, and the US.
International journal of audiology
Int J Audiol
64
sup1
10.1080/14992027.2025.2505979
eng
2,025
4
null
2,025
6
1
[OBJECTIVES] To understand the international experiences of affiliate stigma among significant others of adults with hearing loss; and associations between third-party hearing disability and affiliate stigma. [DESIGN] Cross-sectional online survey and descriptive analyses. [STUDY SAMPLE] 313 significant others of adult...
affiliate stigma; audiology; cross-sectional survey; hearing aids; hearing loss
0.941
102
Linguistics and Language; Speech and Hearing
Health Professions; Social Sciences
2,024
40,459,134
Assessment of the Efficacy of the Hemoglobin, Albumin, Lymphocyte, and Platelet Score in Predicting Recurrence of Atrial Fibrillation Following Cryo-Balloon Ablation.
Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir
Turk Kardiyol Dern Ars
53
4
10.5543/tkda.2025.54829
eng
2,025
6
null
null
null
null
[OBJECTIVE] The Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score has gained interest as a potential predictive biomarker for various clinical outcomes across multiple diseases. This study aimed to evaluate the efficacy of the HALP score in predicting the recurrence of atrial fibrillation (AF) following cryo-b...
null
null
null
null
null
null
40,458,990
Cycle regimens for endometrial preparation prior to frozen embryo transfer.
The Cochrane database of systematic reviews
Cochrane Database Syst Rev
6
6
10.1002/14651858.CD003414.pub4
eng
2,025
6
3
2,025
6
3
[BACKGROUND] Frozen-thawed embryo transfer (FET) use increases the cumulative pregnancy rate, reduces cost and is relatively simple to undertake. FET is performed using different cycle regimens: spontaneous ovulatory (natural) cycles; cycles in which the endometrium is artificially prepared by oestrogen and progesteron...
null
1.623
341
Medicine; Pharmacology
Medicine
2,024
40,458,784
Acute stress disorder in patients with traumatic spinal cord injury: risk factors and coping strategies.
Frontiers in psychiatry
Front Psychiatry
16
null
10.3389/fpsyt.2025.1555589
eng
2,025
null
null
2,025
5
19
[BACKGROUND] Traumatic Spinal Cord Injury (TSCI) exerts a profound negative impact on patients' psychological well-being and daily life. The objective of this study is to dissect the comorbidity of Acute Stress Disorder (ASD) among TSCI patients, identify its contributing factors, and construct a predictive model to pr...
acute stress disorder; care; nursing; traumatic spinal cord injury; treatment
1.192
134
Psychiatry and Mental Health
Medicine
2,024
40,458,777
The mediating role of self-control between physical activity and mobile phone addiction in adolescents: a meta-analytic structural equation modeling approach.
Frontiers in psychiatry
Front Psychiatry
16
null
10.3389/fpsyt.2025.1446872
eng
2,025
null
null
2,025
5
19
[BACKGROUND AND OBJECTIVES] With the rapid advancement of information technology, adolescent cell phone addiction has emerged as a pressing and urgent issue. The combined influence of physical activity (PA) and self-control (SC) on mobile phone addiction (MPA) in adolescents has been investigated in previous studies. H...
adolescents; meta-analysis; mobile phone addiction; physical activity; self-control; structural equation modeling
1.192
134
Psychiatry and Mental Health
Medicine
2,024
40,458,725
The CENPN/STAT3/USP37 signaling axis promotes invasion, migration and metastasis in nasopharyngeal carcinoma.
Frontiers in oncology
Front Oncol
15
null
10.3389/fonc.2025.1536574
eng
2,025
null
null
2,025
5
19
[BACKGROUND] Nasopharyngeal carcinoma (NPC) metastasis is the main cause of poor treatment outcomes and death in nasopharyngeal carcinoma patients. Previously, we reported that centromere protein N (CENPN) is closely related to the pathogenesis, radiotherapy resistance and chemotherapy resistance of nasopharyngeal carc...
CENPN; STAT3; USP37; metastasis; nasopharyngeal carcinoma; transcriptional regulation
1.075
156
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,458,590
Tattoo-less chest wall and regional nodal irradiation using surface imaging.
Technical innovations & patient support in radiation oncology
Tech Innov Patient Support Radiat Oncol
34
null
10.1016/j.tipsro.2025.100310
eng
2,025
6
null
2,025
4
23
[PURPOSE/OBJECTIVE] Skin tattoos represent the standard for surface alignment and setup of breast cancer radiotherapy yet contribute to adverse cosmesis and patient dissatisfaction. With the advent of contemporary surface imaging technology, we evaluated setup accuracy, time, and dosimetric parameters between tradition...
AlignRT; Breast cancer; Surface imaging; Tattoo-less
null
null
null
null
null
40,458,128
Incarceration of the Afferent Loop into the Sutured Closed Mesenteric Defect after Gastrectomy Followed by Billroth-II Reconstruction for Gastric Cancer: Two Case Reports.
Surgical case reports
Surg Case Rep
11
1
10.70352/scrj.cr.25-0167
eng
2,025
null
null
2,025
5
29
[INTRODUCTION] Internal hernia is a critical complication after laparoscopic gastrectomy with Roux-en-Y, Billroth-II or double tract reconstruction. It is recommended that mesenteric defects should be closed to prevent internal hernias. We reported two patients who developed internal hernias, in which the afferent loop...
Billroth-II reconstruction; gastric cancer; internal hernia; laparoscopic surgery; mesenteric defect
null
null
null
null
null
40,458,039
Evaluation of antigen agnostic anti-tumor activity and immune memory induced by CBX-15 (alphalex[TM]-MMAE) in the rat.
Immunotherapy
Immunotherapy
17
7
10.1080/1750743X.2025.2510189
eng
2,025
5
null
2,025
6
3
[AIMS] To determine whether using a pH-sensitive peptide (CBX-15) for antigen-independent targeting of MMAE to tumors induced anti-tumor efficacy via direct and immunological mechanisms in the rat tumor model. [METHODS] CBX-15 was assessed for its ability to kill tumor cells and induce immunogenic cell death (ICD) in f...
CBX-15; anti-tumor cytotoxicity; immune memory; immunogenic cell death; monomethyl auristatin E; pH-low insertion peptide
null
null
null
null
null
40,457,508
The influence of the food environment on diet quality: Insights from an extensive household survey in Ethiopia, focusing on women of reproductive age.
BMC nutrition
BMC Nutr
11
1
10.1186/s40795-025-01097-z
eng
2,025
6
2
2,025
6
2
[BACKGROUND] Undernutrition is a significant challenge in Ethiopia, where limited dietary diversity and widespread micronutrient deficiencies affect millions, especially women of reproductive age. Although much research has explored dietary gaps and practices, the impact of the food environment (FE) on diet quality rem...
Diet quality; Ethiopia; Food access; Food environment; Food systems; Household; Women of reproductive age
0.656
36
Medicine; Nutrition and Dietetics; Public Health, Environmental and Occupational Health; Endocrinology, Diabetes and Metabolism
Medicine; Nursing
2,024
40,457,473
Serum IL-40 is elevated in systemic sclerosis and is linked to disease activity, gastrointestinal involvement, immune regulation and fibrotic processes.
Arthritis research & therapy
Arthritis Res Ther
27
1
10.1186/s13075-025-03570-3
eng
2,025
6
2
2,025
6
2
[BACKGROUND] Interleukin 40 (IL-40) is a cytokine implicated in malignancies and rheumatic disorders. Its association with fibrotic mediators has been previously described. Since inflammation and fibrosis are hallmarks of systemic sclerosis (SSc), we aimed to analyze the role of IL-40 in SSc. [METHODS] IL-40 levels wer...
Biomarkers; Interleukin 40; Systemic sclerosis
null
null
null
null
null
40,457,419
COVID-19 risk perception moderates the relationships between health risk behaviors clustering and anxiety-depression comorbidity in adolescents.
BMC psychology
BMC Psychol
13
1
10.1186/s40359-025-02937-0
eng
2,025
6
2
2,025
6
2
[BACKGROUND] Mental health problems were certainly widespread during the COVID-19 pandemic. The study aimed to examine the associations between clustering patterns of health risk behaviors (HRBs) and anxiety-depression comorbidity among Chinese adolescents, and further explore the moderating role of COVID-19 risk perce...
Adolescents; Anxiety-depression; Behaviors risk; COVID-19; Comorbidity; Health risk; Perception
1.03
49
Medicine; Psychology
Medicine; Psychology
2,024
40,457,404
Modulation of cerebrospinal fluid secretion facilitated by serotonergic and noradrenergic receptors in the rat choroid plexus.
Fluids and barriers of the CNS
Fluids Barriers CNS
22
1
10.1186/s12987-025-00666-5
eng
2,025
6
2
2,025
6
2
[BACKGROUND] The intracranial pressure (ICP) increases at night, partly due to an elevated rate of cerebrospinal fluid (CSF) secretion, which may have therapeutic implications for pressure-related disorders. With similar diurnal regulation in nocturnal rodents and diurnal humans, the diurnally fluctuating CSF dynamics ...
CSF; Choroid plexus; Diurnal; ICP; Noradrenaline
1.931
71
Cellular and Molecular Neuroscience; Developmental Neuroscience; Medicine; Neurology
Medicine; Neuroscience
2,024
40,457,393
Mapping ethical issues encompassing end-of-life care for persons experiencing severe and persistent mental illness: a qualitative study.
BMC medical ethics
BMC Med Ethics
26
1
10.1186/s12910-025-01234-0
eng
2,025
6
2
2,025
6
2
[BACKGROUND] Persons experiencing severe and persistent mental illness (SPMI) represent a small but vulnerable group in mental health care and society. Research on this population is limited, despite significant ethical challenges in their care. These challenges include the severity of their illness, limited social net...
End-of-life care; Ethics; Severe and persistent mental illness (SPMI)
1.082
66
Health Policy; Health; Issues, Ethics and Legal Aspects
Medicine; Nursing; Social Sciences
2,024
40,457,367
Barriers to and enablers of availability and integration of palliative care into routine services at Charlotte Maxeke Johannesburg Academic Hospital, South Africa.
BMC palliative care
BMC Palliat Care
24
1
10.1186/s12904-025-01778-3
eng
2,025
6
2
2,025
6
2
[BACKGROUND] The prevalence of chronic diseases among the South African population is increasing. The incidence of cancers is high and expected to double by 2030 while the HIV burden is disproportionately high. These are indicators of the need for palliative care services in the South African health system. While some ...
Barriers; CFIR; Enablers; Integration; Palliative care
1.046
62
Medicine
Medicine
2,024
40,457,182
Home-based geriatric rehabilitation after inpatient rehabilitation: a redesign and feasibility study.
BMC geriatrics
BMC Geriatr
25
1
10.1186/s12877-025-06043-z
eng
2,025
6
2
2,025
6
2
[BACKGROUND] There is a shift from inpatient to home-based geriatric rehabilitation (HBGR), and potential benefits are demonstrated. Previously, a theoretical HBGR model, version 1.0, has been developed, outlining its essential components. However, clear guidance on the practical design and organisation of HBGR in ever...
Blended eHealth; Co-creation; Community care nursing; Feasibility study; Goal setting; Healthcare professionals; Home-based geriatric rehabilitation; MRC framework; Older adults; Support system
1.335
112
Geriatrics and Gerontology
Medicine
2,024
40,456,512
Special Topic Burnout: Examining Health Professional Trainee Burnout: Lessons Learned Using Qualitative Inquiry to Elicit Rich Data.
Applied clinical informatics
Appl Clin Inform
null
null
10.1055/a-2624-5482
eng
2,025
6
2
2,025
6
2
[BACKGROUND] Health professional (HP) trainee burnout is hard to capture. There are many validated quantitative tools to assess trainee burnout, but fewer qualitative methodological tools that can elicit rich and trustworthy qualitative data on HP trainee burnout. [OBJECTIVE] Report the process, results, and lessons le...
null
0.843
47
Computer Science Applications; Health Informatics; Health Information Management
Computer Science; Health Professions; Medicine
2,024
40,455,342
Effect of Antiretroviral Therapy and Vitamin E Supplementation on Total Antioxidant Capacity in Children Living with HIV.
Indian pediatrics
Indian Pediatr
62
8
10.1007/s13312-025-00111-8
eng
2,025
8
null
2,025
6
2
[OBJECTIVES] To assess the total antioxidant capacity (TAC) in children living with HIV (CLHIV) and to evaluate the effect of antiretroviral therapy (ART) and vitamin E supplementation on TAC. [METHODS] The study included CLHIV on ART ≥ 2 years, ART-naïve CLHIV and healthy controls. CLHIV on ART ≥ 2 years received vita...
Alpha-tocopherol; CLHIV; HAART; Nutrition; Oxidative stress
0.38
63
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,455,319
Reliability of the da Vinci robotic surgical system: a systematic review and pooled analysis of technical failures.
World journal of urology
World J Urol
43
1
10.1007/s00345-025-05732-z
eng
2,025
6
2
2,025
6
2
[PURPOSE] Millions of patients undergo robot-assisted surgery. This technology carries potential risks to perioperative safety. Despite the widespread adoption of robotic platforms, data on the frequency of system malfunctions remain limited. We systematically reviewed and pooled data on the da Vinci robotic system mal...
Da Vinci system; Instrument malfunction; Robotic surgery; Robotic surgery complications; Technical failures
1.055
104
Urology
Medicine
2,024
40,454,422
Clinical Outcomes and in vivo Aberrometry Following the Implantation of a Monofocal IOL with Positive Asphericity.
Clinical ophthalmology (Auckland, N.Z.)
Clin Ophthalmol
19
null
10.2147/OPTH.S519332
eng
2,025
null
null
2,025
5
28
[PURPOSE] To evaluate ocular aberrations, visual and refractive outcomes in eyes implanted with a monofocal intraocular lens (IOL) with a positive asphericity profile. [PATIENTS AND METHODS] This prospective observational study included 42 eyes (27 patients) that underwent routine cataract surgery and implantation of R...
enhanced monofocal IOL; intermediate vision; monofocal IOL; spherical aberration
0.936
84
Ophthalmology
Medicine
2,024
40,454,085
Surgical Management of Destructive Thyroiditis Triggered by Neoadjuvant Immune Checkpoint Inhibitor Therapy in Locally Advanced Non-Small Cell Lung Cancer: A Case Report.
Surgical case reports
Surg Case Rep
11
1
10.70352/scrj.cr.25-0104
eng
2,025
null
null
2,025
5
28
[INTRODUCTION] The use of immune checkpoint inhibitors (ICIs) as neoadjuvant therapies for locally advanced and resectable non-small cell lung cancer is increasing. As a result, immune-related adverse events (irAEs) may be observed before surgery and may require preoperative intervention. We report the case of a patien...
destructive thyroiditis; immune-related adverse event; non-small cell lung cancer; surgery
null
null
null
null
null
40,453,907
Clonal dissemination and persistence of Carbapenem-resistant bla KPC-2 harbouring Klebsiella pneumoniae ST307 in a Tertiary Hospital in the Republic of Korea.
JAC-antimicrobial resistance
JAC Antimicrob Resist
7
3
10.1093/jacamr/dlaf090
eng
2,025
6
null
2,025
5
30
[OBJECTIVES] We investigated the epidemiological patterns of carbapenem-resistant, bla KPC-2 harbouring Klebsiella pneumoniae (K. pneumoniae) ST 307 isolates in a tertiary hospital in South Korea between 2019 and 2021 and compared them to isolates collected from 25 hospitals through a nationwide survey, using whole gen...
null
1.063
29
Infectious Diseases; Microbiology; Immunology; Immunology and Allergy; Microbiology
Immunology and Microbiology; Medicine
2,024
40,453,682
Association of total, plant, and animal protein intake with hypertension among type 2 diabetic patients in Azar cohort population: A cross-sectional study.
Health promotion perspectives
Health Promot Perspect
15
1
10.34172/hpp.025.43378
eng
2,025
5
null
2,025
5
6
[BACKGROUND] The existing research on the relationship between dietary protein intake and hypertension has mainly centered on the general population, with limited information available for adults with type 2 diabetes (T2DM). Therefore, this study was conducted to explore the association of total, plant, and animal prot...
Cross-sectional studies; Diabetes mellitus; Dietary proteins; Hypertension; Type 2
null
null
null
null
null
40,453,185
Chemo-radiotherapy after neoadjuvant chemotherapy and radical hysterectomy in women with stage IB-IIB cervical cancer: Do we need to change the therapeutic approach? A cohort study.
Surgery in practice and science
Surg Pract Sci
21
null
10.1016/j.sipas.2025.100284
eng
2,025
6
null
2,025
4
28
[BACKGROUND] Chemoradiotherapy is recommended as the standard treatment for advanced cervical cancer, and neoadjuvant chemotherapy (NACT) can be beneficial for patients on long radiotherapy waiting lists. This study aimed to evaluate the need for chemoradiotherapy after NACT and radical hysterectomy in women with stage...
Cervical cancer; Chemo-radiotherapy; Neoadjuvant chemotherapy; Progression-free survival; Radical hysterectomy
0.281
8
Otorhinolaryngology; Surgery; Urology
Medicine
2,024