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40,452,777
Evidence from a Comprehensive Bioinformatics Analysis Point to Possible Therapeutic Targets for Vitiligo.
Clinical, cosmetic and investigational dermatology
Clin Cosmet Investig Dermatol
18
null
10.2147/CCID.S523231
eng
2,025
null
null
2,025
5
27
[BACKGROUND] Vitiligo is an autoimmune, hypopigmented dermatological disease for which the pathogenesis remains unclear. With limited therapeutic options, it has a significant treatment burden and adverse psychological effects for patients. [METHODS] The core method employed was Mendelian randomization (MR), which was ...
Bayesian colocalization; Mendelian randomization; drug target; molecular docking; protein quantitative trait loci; vitiligo
0.737
59
Dermatology
Medicine
2,024
40,452,541
Risk factors for HCV infection in Georgia: A case-control study.
Journal of infection in developing countries
J Infect Dev Ctries
19
5
10.3855/jidc.20658
eng
2,025
5
31
2,025
5
31
[INTRODUCTION] Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease, including cirrhosis and liver cancer. Prior studies in Georgia identified risk factors such as injection drug use (IDU), tattoos, dental cleanings, medical injections, and blood transfusion. This study explored risk factors as...
Georgia; HCV transmission; Hepatitis C; injection drug use; invasive medical procedures
0.389
64
Infectious Diseases; Medicine; Microbiology; Parasitology; Virology
Immunology and Microbiology; Medicine
2,024
40,452,520
Colopleurocutaneous fistula associated with empyema as a late complication of colorectal cancer.
Journal of infection in developing countries
J Infect Dev Ctries
19
5
10.3855/jidc.19318
eng
2,025
5
31
2,025
5
31
[INTRODUCTION] Pleurocutaneous fistula is a pathological communication of subcutaneous tissue with the pleural cavity, and can occur as a result of infectious, malignant processes and iatrogenic procedures. Colopleural fistula is rare and is mainly caused by processes in the abdomen. The appearance of empyema is usuall...
Colopleurocutaneous fistula; colorectal cancer; empyema
0.389
64
Infectious Diseases; Medicine; Microbiology; Parasitology; Virology
Immunology and Microbiology; Medicine
2,024
40,451,998
Risk of Post-polypectomy Bleeding After Colorectal Endoscopic Mucosal Resection in Patients with Chronic Kidney Disease: A Propensity-Matched Analysis of the US Collaborative Network.
Digestive diseases and sciences
Dig Dis Sci
null
null
10.1007/s10620-025-09122-8
eng
2,025
6
1
2,025
6
1
[BACKGROUND] Studies evaluating the risk of post-polypectomy bleeding (PPB) after colorectal endoscopic mucosal resection (EMR) in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) are limited. [METHODS] This retrospective cohort study utilized the U.S. Collaborative Network to assess the ri...
Chronic kidney disease; Colorectal polyps; Dialysis; Endoscopic mucosal resection; Post-polypectomy bleeding
1.004
146
Gastroenterology; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,451,677
A shake with cashew and Brazil nuts decreased lipid peroxidation but did not improve antioxidant status in individuals with overweight or obesity: A randomized crossover clinical trial.
Nutrition, metabolism, and cardiovascular diseases : NMCD
Nutr Metab Cardiovasc Dis
null
null
10.1016/j.numecd.2025.104131
eng
2,025
5
16
2,025
5
16
[BACKGROUND AND AIMS] Nuts are recognized for their potential health benefits, yet little is known about their postprandial impact on metabolic responses and oxidative stress. This study aimed to evaluate the acute effect of a shake containing a mixture of 30g cashew nuts (Anacardium occidentale L.) and 15g Brazil nuts...
Cholesterol; Insulin; Linoleic acid; Linolenic acid; Oleic acid; Palmitic acid
1.098
125
Cardiology and Cardiovascular Medicine; Medicine; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Medicine; Nursing
2,024
40,451,614
Diagnostic Ability of Transverse Axial Images Obtained by Optical Coherence Tomography for Detecting Anterior Displacement of Peripapillary Tissues in Papilledema.
Clinical & experimental ophthalmology
Clin Exp Ophthalmol
null
null
10.1111/ceo.14561
eng
2,025
6
1
2,025
6
1
[BACKGROUND] To evaluate the diagnostic ability of optical coherence tomography (OCT) images to detect posterior pole deformation and anterior displacement of the optic disc (ADOD) in papilledema before and after intracranial pressure reduction with medical treatment. Additionally, we compared the analysis of these ima...
anterior displacement of the optic disc; idiopathic intracranial hypertension; papilledema
null
null
null
null
null
40,451,457
Comparative evaluation of indirect-ELISAs based on native antigens of Clostridium chauvoei for the detection of blackleg-specific antibodies in cattle.
Anaerobe
Anaerobe
94
null
10.1016/j.anaerobe.2025.102975
eng
2,025
8
null
2,025
5
30
[OBJECTIVE] Blackleg, also known as black quarter (BQ), is an acute and lethal infection in bovines and caused by the anaerobic bacterium- Clostridium chauvoei. A killed vaccine is available for disease control, and evaluating the immune response to the vaccine or natural infection in susceptible animals is crucial for...
Antibodies; Blackleg; Clostridium chauvoei; ELISA; Flagellar; Whole cell
0.788
99
Infectious Diseases; Microbiology
Immunology and Microbiology; Medicine
2,024
40,451,447
Severe maternal and perinatal-neonatal morbidity associated with planned mode of delivery following a previous cesarean from 2003 to 2021: a population-based cohort study.
American journal of obstetrics and gynecology
Am J Obstet Gynecol
null
null
10.1016/j.ajog.2025.05.021
eng
2,025
5
30
2,025
5
30
[BACKGROUND] Worsening neonatal outcomes over time among planned vaginal births following a previous cesarean were reported in Canada; what drove the change remained unclear. [OBJECTIVE] We aimed to describe time trends in severe maternal and perinatal-neonatal morbidity associated with a planned vaginal birth vs a rep...
induced labor; oxytocin; severe maternal morbidity; trial of labor; uterine rupture; vaginal birth after cesarean
2.772
274
Obstetrics and Gynecology
Medicine
2,024
40,451,344
Association Between Caring for a Disabled Adult and Spousal Caregiver's Chronic Disease: Evidence From a National Study in China.
American journal of preventive medicine
Am J Prev Med
69
4
10.1016/j.amepre.2025.107734
eng
2,025
5
30
2,025
5
30
[INTRODUCTION] Spousal caregiving for disabled adults poses health risks, yet few studies address chronic diseases among caregivers of middle-aged and older spouses. This study explores the impact of caregiving on caregivers' chronic disease. [METHODS] Using data from the China Health and Retirement Longitudinal Study,...
null
2.078
260
Epidemiology; Public Health, Environmental and Occupational Health
Medicine
2,024
40,451,314
Transfer learning for COVID-19 predictive modeling: A multicenter study of 12 hospitals.
Annals of epidemiology
Ann Epidemiol
108
null
10.1016/j.annepidem.2025.05.013
eng
2,025
8
null
2,025
5
30
[PURPOSE] To use transfer learning to predict Intensive Care Unit admission (ICU) for COVID-19 patients in a multicenter setting. [METHODS] We trained XGBoost algorithms using demographic and laboratory predictors recorded during hospital admissions across 12 hospitals. Our goal was to identify the best-performing hosp...
COVID-19; Intensive Care Unit; Multicenter study; Transfer learning
1.2
145
Epidemiology
Medicine
2,024
40,451,285
Early mortality in patients with acute ischemic stroke after endovascular stroke therapy.
Journal of neurointerventional surgery
J Neurointerv Surg
null
null
10.1136/jnis-2025-023517
eng
2,025
6
1
2,025
6
1
[BACKGROUND/AIM] Endovascular stroke therapy (EVT) improves functional outcome and reduces mortality in patients with large vessel occlusion. However, data on risk factors for early mortality after EVT are scarce. We investigated the predictive value of clinical information already available on the day of hospital admi...
Stroke; Thrombectomy
1.634
90
Medicine; Neurology; Surgery
Medicine
2,024
40,451,175
Prevalence and Associations of Anxiety Symptoms among Young Overweight or Obese Patients with Major Depressive Disorder.
Psychopathology
Psychopathology
null
null
10.1159/000546692
eng
2,025
5
30
2,025
5
30
[INTRODUCTION] Overweight or obesity often co-occurs with depression among young adults. Major depressive disorder (MDD) frequently occurs alongside anxiety; nevertheless, research exploring the interaction between anxiety symptoms and MDD in young adults with overweight or obesity is limited. This study aimed to inves...
Anxiety; Comorbidity; Major depressive disorder; Obesity; Young adults
0.858
77
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
40,451,125
Comparison of quality, empathy and readability of physician responses versus chatbot responses to common cerebrovascular neurosurgical questions on a social media platform.
Clinical neurology and neurosurgery
Clin Neurol Neurosurg
255
null
10.1016/j.clineuro.2025.108986
eng
2,025
8
null
2,025
5
28
[BACKGROUND] Social media platforms are utilized by patients prior to scheduling formal consultations and also serve as a means of pursuing second opinions. Cerebrovascular pathologies require regular surveillance and specialized care. In recent years, chatbots have been trained to provide information on neurosurgical ...
Artificial intelligence; Chatbot; Large language models; Social media; Vascular neurosurgery
0.594
89
Medicine; Surgery; Neurology
Medicine
2,024
40,450,842
Calf circumference is a useful muscle mass marker for predicting length of stay and mortality: A secondary analysis of a cohort study in hospitalized individuals.
Nutrition (Burbank, Los Angeles County, Calif.)
Nutrition
138
null
10.1016/j.nut.2025.112819
eng
2,025
10
null
2,025
4
26
[OBJECTIVE] To evaluate the accuracy of calf circumference (CC) and determine its association with clinical outcomes of hospitalized patients. [METHODS] This is a secondary analysis of a prospective cohort study of inpatient. CC values were adjusted by body mass index (BMI) to remove adiposity's confounding effects: th...
Calf circumference; Hospital mortality; Inpatients; Length of stay; Muscle mass
0.961
168
Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics
Medicine; Nursing
2,024
40,450,787
Assessment of thyroid-associated ophthalmopathy activity using corrected standardised uptake value maximum (SUVmax) and uptake ratios from 99Tcm-diethylene triamine pentaacetic acid single photon emission computed tomography/computed tomography (99Tcm-DTPA SPECT/CT) imaging.
Clinical radiology
Clin Radiol
86
null
10.1016/j.crad.2025.106946
eng
2,025
7
null
2,025
5
6
[AIM] This study evaluated the utility of corrected maximum standardized uptake value (SUVmax) in assessing thyroid-associated ophthalmopathy (TAO) activity through 99Tcm-diethylene triamine pentaacetic acid (99Tcm-DTPA) SPECT/CT imaging. [MATERIALS AND METHODS] A total of 166 orbits from 83 TAO patients were analyzed,...
null
0.622
110
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,450,733
Prognostic value of health-related quality of life in patients with acute dyspnoea: a cohort study.
Swiss medical weekly
Swiss Med Wkly
155
null
10.57187/s.3785
eng
2,025
4
15
2,025
4
15
[BACKGROUND] Self-reported health-related quality of life is an established prognostic tool in stable outpatients. However, its prognostic relevance in patients presenting with an acute onset of symptoms such as acute dyspnoea is largely unknown. [METHODS] This major unmet clinical need was addressed in a secondary ana...
null
null
null
null
null
null
40,450,298
Understanding the clinical morbidity and mortality of fibrodysplasia ossificans progressiva: a systematic literature review.
Orphanet journal of rare diseases
Orphanet J Rare Dis
20
1
10.1186/s13023-025-03763-8
eng
2,025
5
31
2,025
5
31
[BACKGROUND] Fibrodysplasia ossificans progressiva (FOP) is an autosomal dominant ultra-rare disease characterized by progressive episodic multi-focal heterotopic ossification of skeletal muscle, ligaments, tendons, and fascia. Comprehensive characterization and understanding of the natural disease history of FOP, incl...
Comorbidity; Epidemiology; Fibrodysplasia ossificans progressiva; Medication use; Mortality; Systematic literature review
1.269
143
Genetics; Medicine; Pharmacology
Medicine
2,024
40,450,209
Sex and age differences in cortisol levels during glucagon stimulation test in children.
BMC pediatrics
BMC Pediatr
25
1
10.1186/s12887-025-05784-5
eng
2,025
5
31
2,025
5
31
[BACKGROUND] Previous studies of glucagon stimulation test (GST) in children have shown variable results regarding the utility and reliability of the cortisol response to this test and its correlation with clinical parameters. The aim of this study was to assess cortisol levels at GST and to evaluate how clinical param...
Child; Childhood; Cortisol; Glucagon test; Sex-differences
0.734
106
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,450,194
Long-Term Oncological Outcomes After Complete Mesocolic Excision Versus Standard Resection for Right-Sided Colon Cancer: A Propensity Score Matching Analysis.
Journal of gastrointestinal cancer
J Gastrointest Cancer
56
1
10.1007/s12029-025-01248-2
eng
2,025
5
31
2,025
5
31
[BACKGROUND] Complete mesocolic excision (CME) has not gained wide diffusion, mainly due to its technical complexity and unclear oncological benefits. We investigated the long-term outcomes of patients with right-sided colon cancer who underwent CME surgery compared to those treated with conventional surgery (NCME). [M...
Complete mesocolic excision; Local recurrence; Propensity score matching; Right colon cancer
0.516
54
Gastroenterology; Oncology
Medicine
2,024
40,449,955
NeoPred: dual-phase CT AI forecasts pathologic response to neoadjuvant chemo-immunotherapy in NSCLC.
Journal for immunotherapy of cancer
J Immunother Cancer
13
5
10.1136/jitc-2025-011773
eng
2,025
5
31
2,025
5
31
[BACKGROUND] Accurate preoperative prediction of major pathological response or pathological complete response after neoadjuvant chemo-immunotherapy remains a critical unmet need in resectable non-small-cell lung cancer (NSCLC). Conventional size-based imaging criteria offer limited reliability, while biopsy confirmati...
Adjuvant; Immunotherapy; Lung Cancer
4.22
136
Cancer Research; Immunology; Immunology and Allergy; Molecular Medicine; Oncology; Pharmacology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,449,843
Differential MYC Phosphorylation Drives the Divergent Cholangiocyte Response to Stress.
Cellular and molecular gastroenterology and hepatology
Cell Mol Gastroenterol Hepatol
19
10
10.1016/j.jcmgh.2025.101547
eng
2,025
5
29
2,025
5
29
[BACKGROUND AND AIMS] In primary sclerosing cholangitis (PSC), some cholangiocytes undergo cell cycle arrest (senescence), whereas others proliferate (ductular reaction). Our aim was to determine the mechanisms driving this divergent response. [METHODS] We analyzed PSC and control liver tissue by immunofluorescence for...
Ductular Reaction; Primary Sclerosing Cholangitis; Proliferation; Senescence
3.069
75
Gastroenterology; Hepatology
Medicine
2,024
40,449,382
Mesenchymal circulating tumor cells as prognostic markers in HCC Post-Transplantation: Sirolimus as a potential therapeutic Modulator.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Eur J Surg Oncol
51
9
10.1016/j.ejso.2025.110147
eng
2,025
5
15
2,025
5
15
[BACKGROUND] The prognostic value of CTCs for post-LT tumor recurrence remains insufficiently studied, and the associations between CTCs and immunosuppressants remain unclear. [METHODS] This study analyzed 277 HCC patients undergoing liver transplantation. MCTC and ECTC levels were measured from the day of surgery to o...
Hepatocellular carcinoma recurrence; Liver transplantation; Mesenchymal circulating tumor cells; Sirolimus
1.153
123
Medicine; Surgery; Oncology
Medicine
2,024
40,449,239
Effects of motivational interviews and hippotherapy on the digital game addiction levels of adolescents: Randomized controlled clinical trial.
Journal of pediatric nursing
J Pediatr Nurs
84
null
10.1016/j.pedn.2025.05.024
eng
2,025
5
30
2,025
5
30
[AIM] The increasing prevalence of digital game addiction in children and adolescent remains a significant public health problem worldwide. This randomized controlled study was carried out to determine the effects of motivational interviews based on the information-motivation-behavioral skills model, health education, ...
Adolescent; Digital game addiction; Hippotherapy; Information-motivation-behavioral skills model; Nursing
0.798
78
Pediatrics
Nursing
2,024
40,449,078
Temperament and risk of disability pensions in early middle age: A 22-year follow-up study of the northern Finland birth cohort 1966.
Journal of psychosomatic research
J Psychosom Res
195
null
10.1016/j.jpsychores.2025.112172
eng
2,025
8
null
2,025
5
29
[OBJECTIVES] We examined whether temperament traits, individual biological tendencies to react to stimuli, predict disability pensions. [METHODS] We surveyed the temperament traits (novelty seeking, harm avoidance, reward dependence and persistence) of the Northern Finland Birth Cohort 1966 Study participants (n = 4713...
Disability retirement; Harm avoidance; Personality; Temperament
1.308
182
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
40,448,547
An Electronic Clinical Surveillance System to Reduce Failure to Follow Up Abnormal Lab Results and Failure to Order Needed Tests: Description and Methods.
The journal of applied laboratory medicine
J Appl Lab Med
null
null
10.1093/jalm/jfaf073
eng
2,025
5
31
2,025
5
31
[BACKGROUND] Failure to follow up abnormal test results in a timely manner is a widespread issue in outpatient settings. The etiologies of this problem are multidimensional and vary across settings. While there is currently no widely used intervention to address these issues, multiple studies have noted that there is a...
null
0.603
31
Analytical Chemistry; Biochemistry; Chemical Engineering; Pathology and Forensic Medicine; Clinical Biochemistry
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Medicine
2,024
40,448,422
Number of Remaining Teeth and Obesity in Chilean Older Adults.
Gerodontology
Gerodontology
null
null
10.1111/ger.12827
eng
2,025
5
31
2,025
5
31
[OBJECTIVES] To investigate whether the number of remaining teeth was associated with obesity among Chilean older people. [BACKGROUND] Contradictory findings on the associations between cumulative tooth loss, chewing discomfort and the consumption of fruits and vegetables in older people have been reported; moreover, f...
Chile; functional dentition; obesity; older adults; remaining teeth; tooth loss
0.796
69
Dentistry; Geriatrics and Gerontology
Dentistry; Medicine
2,024
40,448,356
Descriptive analysis of national bovine viral diarrhoea test data in England (2016-2023).
The Veterinary record
Vet Rec
null
null
10.1002/vetr.5325
eng
2,025
5
30
2,025
5
30
[BACKGROUND] Bovine viral diarrhoea (BVD) is an endemic disease in the UK. In England, a voluntary control and eradication scheme, BVDFree England, has been running since 2016. [METHODS] We analysed test results from 7005 herds that were submitted to BVDFree England between 2016 and 2023 to investigate changes in the p...
null
0.403
116
Veterinary; Medicine
Medicine; Veterinary
2,024
40,448,260
Aromatase inhibitors therapy and major osteoporotic fracture risk in postmenopausal breast cancer patients: a nationwide real-world cohort study.
Breast cancer research : BCR
Breast Cancer Res
27
1
10.1186/s13058-025-02050-5
eng
2,025
5
30
2,025
5
30
[BACKGROUND] The increased risk of fractures associated with aromatase inhibitors (AIs) therapy has been well established in clinical trials; however, data on Asian populations remain limited. Furthermore, the impact of AIs on fracture risk across different age groups and breast cancer stages has not been thoroughly in...
Aromatase inhibitors; Breast cancer; Major osteoporotic fractures; Tamoxifen
2.202
182
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,448,221
Compositional and functional gut microbiota alterations in mild cognitive impairment: links to Alzheimer's disease pathology.
Alzheimer's research therapy
Alzheimers Res Ther
17
1
10.1186/s13195-025-01769-9
eng
2,025
5
30
2,025
5
30
[BACKGROUND] Emerging evidence highlights the bidirectional communication between the gut microbiota and the brain, suggesting a potential role for gut dysbiosis in Alzheimer's disease (AD) pathology and cognitive decline. Existing literature on gut microbiota lacks species-level insights. This study investigates gut m...
APOE; Amyloid PET; Gut microbiome; Gut-brain axis; Mild cognitive impairment; Plasma pTau181; Shotgun metagenomics
null
null
null
null
null
40,448,206
Upregulation of miR-17-3p is associated with HbF in patients with β-thalassemia and induces γ-globin expression by targeting BCL11A.
Orphanet journal of rare diseases
Orphanet J Rare Dis
20
1
10.1186/s13023-025-03806-0
eng
2,025
5
30
2,025
5
30
[BACKGROUND] Large number of microRNAs (miRNAs) have been found to be dysregulated in β-thalassemia, but their roles in β-thalassemia are poorly reported. This study aims to investigate the clinical significance of miR-17-3p in β-thalassemia, and to elucidate its regulatory effect on erythropoiesis and γ-globin express...
BCL11A; Erythropoiesis; HbF; miR-17-3p
1.269
143
Genetics; Medicine; Pharmacology
Medicine
2,024
40,448,121
Promoting data-driven decision-making in Jordan: strengthening national health information system and achieving consensus on core set of health system indicators.
Reproductive health
Reprod Health
22
Suppl 1
10.1186/s12978-025-01988-1
eng
2,025
5
31
2,025
5
31
[BACKGROUND] A well-functioning health information system (HIS) is foundational for strong health systems and the achievement of the Sustainable Development Goals. In Jordan, the national HIS, overseen by the Ministry of Health, faces challenges related to overlapping data collection, data availability gaps, and operat...
Adolescent indicators; Consensus meetings; Core health systems; Data-driven decision-making; Health information system; Indicators; Jordan; Maternal and child health indicators; Refugee health indicators
1.275
84
Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,024
40,448,100
Social contextual factors, social support and accessibility of social services in the health and life satisfaction of family caregivers in Hong Kong.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-23307-w
eng
2,025
5
30
2,025
5
30
[PURPOSE] Health issues and life satisfaction among family caregivers have attracted significant public and scholarly attention, but research on socio-demographic and social contextual factors contributing to family caregivers' burdens remains limited in scope. This study aims to assess the factors associated with subj...
Caregiver burden; Family caregiver; Health; Life satisfaction; Mental health; Social support
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,448,095
An objective test to assess upper limb functionality in patients with breast cancer-related lymphedema: investigation of the psychometric properties of the upper limb functional test (ULIFT).
BMC women's health
BMC Womens Health
25
1
10.1186/s12905-025-03829-6
eng
2,025
5
30
2,025
5
30
[BACKGROUND] Although upper limb (UL) functionality was reported to be adversely affected in patients with breast cancer- related lymphedema (BCRL), there is currently no validated, objective performance-based assessment tool designed to evaluate UL function in this population. The Upper Limb Functional Test (ULIFT) wa...
Breast cancer; Physical functional performance; Reproducibility; Upper extremity lymphedema
0.925
73
Medicine; Obstetrics and Gynecology; Reproductive Medicine
Medicine
2,024
40,448,088
Applying the theory of planned behavior to examine breastfeeding determinants in countries of the Gulf Cooperation Council: a systematic review.
International breastfeeding journal
Int Breastfeed J
20
1
10.1186/s13006-025-00739-z
eng
2,025
5
30
2,025
5
30
[BACKGROUND] Appropriate and timely nutrition during infancy constitutes a critical window of opportunity to ensure proper growth and development. Despite the established benefits of breastfeeding (BF), the proportions of breastfed infants remain disappointingly low in countries of the Gulf Cooperation Council (GCC). U...
Attitudes; Beliefs; Breastfeeding; Gulf Cooperation Council; Intentions; Perceived behavioral control; Subjective norms; Systematic review; Theory of planned behavior
0.989
60
Obstetrics and Gynecology; Pediatrics, Perinatology and Child Health
Medicine
2,024
40,448,081
Behavior of test specificity under an imperfect gold standard: findings from a simulation study and analysis of real-world oncology data.
BMC medical research methodology
BMC Med Res Methodol
25
1
10.1186/s12874-025-02603-4
eng
2,025
5
30
2,025
5
30
[BACKGROUND] Gold standards used in validation of new tests may be imperfect, with sensitivity or specificity less than 100%. The impact of imperfection in a gold standard on measured test attributes has been demonstrated formally, but its relevance in real-world oncology research may not be well understood. [METHODS] ...
Death; Endpoint; Gold standard; Mortality; Prevalence; Sensitivity; Specificity; Suppression; Test; Validation
1.669
176
Epidemiology; Health Informatics
Medicine
2,024
40,448,069
Weight-related bullying in schools: a review of school anti-bullying policies.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-23170-9
eng
2,025
5
30
2,025
5
30
[INTRODUCTION] Weight is reported to be the most common target for bullying at school - far more common than other targets such as ethnicity, religion or sexual orientation. Research suggests weight bias and stigma - including negative beliefs, attitudes and discriminatory behaviours related to a person's weight - is p...
Bias; Bullying; Obesity; Policy; School; Stigma; UK; Victimisation; Weight
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,447,897
Color differences of intraprocedural bleeding between white light and red dichromatic imaging during endoscopic submucosal dissection: a post hoc analysis of a multicenter, open-label, randomized controlled trial (with videos).
Surgical endoscopy
Surg Endosc
39
7
10.1007/s00464-025-11809-y
eng
2,025
7
null
2,025
5
30
[BACKGROUND] Red dichromatic imaging (RDI) is an image-enhanced endoscopy expected to improve the visibility of bleeding source. We aimed to analyze color difference and hemostasis time between white light imaging (WLI) and RDI during endoscopic submucosal dissection (ESD). [METHODS] This was a single-center post hoc a...
Color difference; Image-enhanced endoscopy; Red dichromatic imaging
1.023
178
Surgery
Medicine
2,024
40,447,865
Regulation of Autophagy by the Cdk1/p53/p21 Feedback Loop in an Interstitial Cystitis/Bladder Pain Syndrome Cell Model: Implications for Inflammatory Response.
International urogynecology journal
Int Urogynecol J
null
null
10.1007/s00192-025-06169-z
eng
2,025
5
30
2,025
5
30
[INTRODUCTION AND HYPOTHESIS] The Cdk1/p53/p21 feedback loop could play an important role in maintaining a consistently high urinary tract epithelial permeability. This study is aimed at elucidating whether this feedback loop is associated with the inadequate autophagic response and the heightened inflammatory response...
Autophagy; Cdk1/p53/p21; Feedback loop; Inflammatory response
0.778
109
Obstetrics and Gynecology; Urology
Medicine
2,024
40,447,864
Female Urinary Incontinence in Africa: Prevalence Estimates from a Systematic Review and Meta-Analysis.
International urogynecology journal
Int Urogynecol J
null
null
10.1007/s00192-025-06146-6
eng
2,025
5
30
2,025
5
30
[INTRODUCTION] This systematic review and meta-analysis aimed to investigate the prevalence of urinary incontinence (UI) among women in African countries. Different types of UI, racial distributions, geographic locations, and methodological approaches were analyzed and compared. [METHODS] A systematic search was conduc...
Africa; Female; Prevalence; Urinary incontinence
0.778
109
Obstetrics and Gynecology; Urology
Medicine
2,024
40,447,552
Is low heart rate variability associated with cardiometabolic dysfunction in children with obesity? A cross-sectional study.
Nutrition, metabolism, and cardiovascular diseases : NMCD
Nutr Metab Cardiovasc Dis
null
null
10.1016/j.numecd.2025.104116
eng
2,025
5
6
2,025
5
6
[BACKGROUND AND AIM] Children with obesity have impaired cardiac function and increased risk of cardiometabolic dysfunction. We investigated children with obesity and low heart rate variability (HRV) in terms of anthropometric parameters, insulin resistance, food addiction (FA), and blood pressure, comparing them with ...
Autonomic nervous system; Childhood obesity; Cortisol; Food addiction; Heart rate variability
1.098
125
Cardiology and Cardiovascular Medicine; Medicine; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Medicine; Nursing
2,024
40,447,195
Introduction of allergenic foods after treatment with omalizumab.
The Journal of allergy and clinical immunology
J Allergy Clin Immunol
156
2
10.1016/j.jaci.2025.05.014
eng
2,025
8
null
2,025
5
28
[BACKGROUND] Omalizumab has been shown to increase reaction thresholds to allergenic foods during treatment. Little is known about its potential to permit introduction of allergenic foods. [OBJECTIVE] The aim of this study was to examine introduction of allergenic foods after stopping treatment with omalizumab. [METHOD...
Omalizumab; anti-IgE; food allergy
3.935
350
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
40,447,107
One-stop shopping for recovery? A systematic review of the evidence on U.S. recovery community centers.
Journal of substance use and addiction treatment
J Subst Use Addict Treat
175
null
10.1016/j.josat.2025.209723
eng
2,025
8
null
2,025
5
28
[BACKGROUND] Increased recognition of the need for community-based substance use disorder (SUD) recovery support services (RSS) to complement and extend clinical care efforts has led to growth in a variety of RSS including recovery community centers (RCCs). Given increased national focus on expanding RCC research, this...
Peer recovery support service; Recovery; Recovery coaching; Recovery community centers; Recovery support services
1.461
127
Medicine; Psychiatry and Mental Health
Medicine
2,024
40,447,029
Association between residential greenspace and anaemia prevalence among Indian women of reproductive age.
Environmental research
Environ Res
282
null
10.1016/j.envres.2025.121985
eng
2,025
10
1
2,025
5
28
[BACKGROUND] Anaemia, characterised by low haemoglobin (Hb) levels, is a serious health issue for women of reproductive age (WRA). A few studies, with inconclusive evidence, suggest that increasing residential greenspace may help reduce the anaemia burden. However, the relationship between greenspace and anaemia and th...
Anaemia; Enhanced vegetation index; Greenspaces; Haemoglobin levels; National Family Health Survey; Nitrogen dioxide; Particulate matter
1.822
196
Biochemistry; Environmental Science; Public Health, Environmental and Occupational Health
Biochemistry, Genetics and Molecular Biology; Environmental Science; Medicine
2,024
40,446,557
Paediatric ventriculoperitoneal shunt obstruction and cerebrospinal fluid protein.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
J Clin Neurosci
137
null
10.1016/j.jocn.2025.111341
eng
2,025
7
null
2,025
5
29
[BACKGROUND] Ventriculoperitoneal shunt (VPS) insertion is a life-saving intervention for hydrocephalus. Device failure is extremely common, and carries immense morbidity for patients, their families, and the healthcare system. Predicting shunt obstruction remains a substantial challenge. Clinically, cerebrospinal flui...
CSF Protein; Hydrocephalus; Obstruction; Shunt failure
0.654
104
Medicine; Surgery; Neurology; Neurology; Physiology
Medicine; Neuroscience
2,024
40,446,148
Comparative Efficacy of MultiModal AI Methods in Screening for Major Depressive Disorder: Machine Learning Model Development Predictive Pilot Study.
JMIR formative research
JMIR Form Res
9
null
10.2196/56057
eng
2,025
5
30
2,025
5
30
[BACKGROUND] Conventional approaches for major depressive disorder (MDD) screening rely on two effective but subjective paradigms: self-rated scales and clinical interviews. Artificial intelligence (AI) can potentially contribute to psychiatry, especially through the use of objective data such as objective audiovisual ...
MDD; artificial intelligence; computational psychiatry; facial action unit; major depressive disorder; multimodal analysis; multiparadigm analysis
0.723
31
Health Informatics; Medicine
Medicine
2,024
40,446,076
Evaluating Artificial Intelligence-Based Writing Assistance Among Published Orthopaedic Studies: Detection and Trends for Future Interpretation.
The Journal of bone and joint surgery. American volume
J Bone Joint Surg Am
null
null
10.2106/JBJS.24.01462
eng
2,025
5
30
2,025
5
30
[BACKGROUND] The integration of artificial intelligence (AI), particularly large language models (LLMs), into scientific writing has led to questions about its ethics, prevalence, and impact in orthopaedic literature. While tools have been developed to detect AI-generated content, the interpretation of AI detection per...
null
null
null
null
null
null
40,445,619
Initiating Injectable Buprenorphine in People Hospitalized With Infections: A Randomized Clinical Trial.
JAMA network open
JAMA Netw Open
8
5
10.1001/jamanetworkopen.2025.13000
eng
2,025
5
1
2,025
5
1
[IMPORTANCE] Hospitalizations are increasing in the US due to infections related to opioid use disorder (OUD); however, few patients have treatment with medications for OUD (MOUD) initiated. Injectable long-acting buprenorphine (LAB) could help improve MOUD receipt and infection treatment completion. [OBJECTIVE] To com...
null
3.546
154
Medicine
Medicine
2,024
40,445,565
Ultrasound-based statistical shape modeling for prognosis in unstable hip dysplasia.
The ultrasound journal
Ultrasound J
17
1
10.1186/s13089-025-00419-3
eng
2,025
5
30
2,025
5
30
[BACKGROUND] Current methods to classify developmental dysplasia of the hip (DDH) on ultrasound (US) images, such as the Graf method, provide limited prognostic information. This study aimed to improve the prediction of the clinical course and outcome at age five of decentered hips, diagnosed on the first US made in th...
DDH; Dysplasia; Hip; Neonatal; SSM; Statistical shape modeling; Ultrasound; Unstable
0.784
43
Radiology, Nuclear Medicine and Imaging; Radiological and Ultrasound Technology
Health Professions; Medicine
2,024
40,445,422
Absolute blood levels and kinetics of neurofilament light (NFL) chains for neurological prognosis in comatose patients after cardiac arrest.
Annals of intensive care
Ann Intensive Care
15
1
10.1186/s13613-025-01491-7
eng
2,025
5
30
2,025
5
30
[INTRODUCTION] Despite current guidelines, the prognosis of comatose patients after cardiac arrest (CA) remains indeterminate in approximately 50% of patients. Neurofilament light (NFL) chain, a biomarker of neuronal injury, appears to be a promising tool with better prognostic value compared to neuron-specific enolase...
Biomarkers; Cardiac arrest; Coma; Neurofilament light chain; Neuron-specific enolase; Neuropronostication
1.576
85
Critical Care and Intensive Care Medicine
Medicine
2,024
40,445,384
Impact of innate lymphoid cell type 2 in chronic lymphocytic leukemia on the function of treg and CD8[+] T cells through IL-9.
Cancer immunology, immunotherapy : CII
Cancer Immunol Immunother
74
7
10.1007/s00262-025-04082-4
eng
2,025
5
30
2,025
5
30
[OBJECTIVE] This study investigated the impact of innate lymphoid cell type 2 (ILC2s) on the function of regulatory T cells (Treg) and CD8[+] T cells in chronic lymphocytic leukemia (CLL) through IL-9. [METHODS] Peripheral blood samples were collected from CLL patients (n = 52) and healthy controls (n = 30). ILC2 propo...
CD8+ T cells; Chronic lymphocytic leukemia; IL-9; Regulatory T cells (Treg); Type 2 innate lymphoid cells (ILC2s)
1.716
142
Cancer Research; Immunology; Immunology and Allergy; Medicine; Oncology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,024
40,445,356
The role of vitamin D deficiency in the development and severity of oral lichen planus: a case-control study.
Clinical oral investigations
Clin Oral Investig
29
6
10.1007/s00784-025-06398-y
eng
2,025
5
30
2,025
5
30
[OBJECTIVES] Examine the responsibility of Vitamin D (VD) deficit as a risk element in the development and severity of oral lichen planus (OLP) considering dietary habits, sex, sun exposure, socioeconomic class and psychological factors. [MATERIALS AND METHODS] Blood samples from 35 OLP patients and 35 healthy controls...
Anxiety; Depression; Oral lichen planus; Serum vitamin D; Severity; Sun exposure; Vitamin D deficiency
0.983
108
Dentistry
Dentistry
2,024
40,445,262
Positive changes in employment status are associated with reduced alcohol use frequency at discharge from outpatient specialty treatment.
Alcohol, clinical experimental research
Alcohol Clin Exp Res (Hoboken)
49
6
10.1111/acer.70044
eng
2,025
6
null
2,025
5
30
[BACKGROUND] Workforce engagement can provide structure, income, feelings of accomplishment, and personal contacts, growing an individual's recovery capital (RC). Employed individuals are also more likely to complete addiction treatment. We sought to investigate whether changes in employment status from alcohol treatme...
TEDS; addiction medicine; encounter; epidemiology; trajectory
null
null
null
null
null
40,445,200
Association between sleep-disordered breathing and moderate to severe depression in systemic lupus erythematosus: the TRUMP2-SLE study.
Modern rheumatology
Mod Rheumatol
null
null
10.1093/mr/roaf047
eng
2,025
5
30
2,025
5
30
[OBJECTIVES] Depression is a common mood disorder in systemic lupus erythematosus (SLE) patients, affecting quality of life and medication adherence. Sleep-disordered breathing (SDB) is a known contributor to depression in the general population, but its prevalence and impact on depression in SLE remain unclear. This s...
depression; sleep-disordered breathing; systemic lupus erythematosus
0.821
71
Medicine; Rheumatology
Medicine
2,024
40,444,814
Pre-treatment lysis time of plasma-derived fibrin clots and bleeding in patients on oral anticoagulants for atrial fibrillation in the ARISTOTLE trial.
European heart journal
Eur Heart J
null
null
10.1093/eurheartj/ehaf347
eng
2,025
5
30
2,025
5
30
[BACKGROUND AND AIMS] Oral anticoagulation reduces stroke risk in patients with atrial fibrillation (AF) but increases bleeding. Longer fibrin clot lysis time has been shown to predict adverse cardiovascular outcomes in acute coronary syndromes. This study explored relationships between fibrin clot lysis time at random...
Anticoagulation; Atrial fibrillation; Bleeding; Fibrinolysis
null
null
null
null
null
40,444,807
The use of water flosser in implant-supported fixed prosthesis: a narrative review and the opinion of Italian dental hygienists.
Minerva dental and oral science
Minerva Dent Oral Sci
74
4
10.23736/S2724-6329.25.05105-8
eng
2,025
8
null
2,025
5
30
[INTRODUCTION] The aim of the present study was to evaluate the opinion of Italian dental hygienists about the use of domiciliary water flosser for the oral hygiene of implant-supported fixed prostheses. [EVIDENCE ACQUISITION] A narrative review of the literature is presented, and a digital questionnaire was shared on ...
null
0.297
35
Oral Surgery; Otorhinolaryngology; Surgery
Dentistry; Medicine
2,024
40,444,622
ARL6IP1 Inhibits Breast Cancer Tumor Progression by Targeting OLFM4 to Regulate Glycolysis.
Combinatorial chemistry high throughput screening
Comb Chem High Throughput Screen
null
null
10.2174/0113862073358595250211053816
eng
2,025
5
27
2,025
5
27
[BACKGROUND] ARL6IP1 has been linked to cancer progression, but its precise role in BC, particularly in metabolism and its interaction with an OLFM4, remains unclear. [AIMS] This study aimed to investigate the role of ADP-ribosylation factor-like 6 interacting protein 1 (ARL6IP1) in breast cancer (BC) cell behavior and...
ARL6P1; Breast cancer; OLFM4; glycolysis; tumor progression.
null
null
null
null
null
40,444,243
Chronic BPAF exposure differentially enhances fat deposition in mice fed normal or high-fat diets via lipid metabolism dysregulation.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
16
null
10.3389/fendo.2025.1571076
eng
2,025
null
null
2,025
5
15
[BACKGROUND] Bisphenol AF (BPAF), an alternative to Bisphenol A (BPA), is increasingly utilized in various industrial applications, yet its toxicological profile remains incompletely understood. This study aims to investigate the impact of BPAF exposure on obesity and lipid metabolism in male mice subjected to either a...
BPAF; fat accumulation; high-fat diet; lipid metabolism; obesity
1.472
138
Endocrinology, Diabetes and Metabolism
Medicine
2,024
40,444,222
Using technology to provide individualized respite for caregivers in rural communities.
Frontiers in health services
Front Health Serv
5
null
10.3389/frhs.2025.1575763
eng
2,025
null
null
2,025
5
15
[INTRODUCTION] Caregiving for older adults-by family and friends-is an essential component of the U.S. health and long-term care systems. Though often rewarding, caregiving is associated with higher rates of poor health. Respite is valued by caregivers and associated with positive outcomes; however, access is limited. ...
caregivers; older adults; respite; rural health; technology
0.956
13
Medicine
Medicine
2,024
40,443,677
Clinical characteristics, prognosis, and predictive modeling in class IV ± V lupus nephritis.
Frontiers in immunology
Front Immunol
16
null
10.3389/fimmu.2025.1580146
eng
2,025
null
null
2,025
5
15
[OBJECTIVE] The objective of this study is to compare the clinical features and survival outcomes of class IV ± V lupus nephritis (LN) patients, identify risk factors, and develop an accurate prognostic model. [METHODS] This study enrolled patients diagnosed with class IV ± V LN by renal biopsy at Xijing Hospital from ...
lupus nephritis; machine learning; prognostic model; risk factors
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
40,443,516
Comparison of thoracoscopy-guided thoracic paravertebral block and patient-controlled intravenous analgesia for postoperative analgesia after uniportal thoracoscopic pulmonary wedge resection: a prospective randomized controlled trial.
Frontiers in medicine
Front Med (Lausanne)
12
null
10.3389/fmed.2025.1554515
eng
2,025
null
null
2,025
5
15
[INTRODUCTION] Patients often experience persistent, intense pain following uniportal thoracoscopic pulmonary wedge resection (UTPWR). This pain is usually intervened with patient-controlled intravenous analgesia (PCIA) or thoracoscopic-guided thoracic paravertebral block (TG-TPB), a novel peripheral nerve block techni...
patient-controlled intravenous analgesic; postoperative analgesia; pulmonary wedge resection; thoracic paravertebral block; thoracoscopic-guided; uniportal thoracoscopy
0.962
102
Medicine
Medicine
2,024
40,443,190
Prevalence of Mental Health Disorders in General Practice from 2014 to 2024: A literature review and discussion paper.
Irish journal of psychological medicine
Ir J Psychol Med
null
null
10.1017/ipm.2025.24
eng
2,025
5
30
2,025
5
30
[BACKGROUND] Many consultations in primary care involve patients with mental health problems, and primary care is typically the place where many such patients initially seek help. While considerable research has examined the prevalence of mental health disorders in primary care, relatively few papers have examined this...
Family practice; general practice; mental health disorders; prevalence; primary care; screening
0.699
37
History and Philosophy of Science; Applied Psychology; Psychiatry and Mental Health
Arts and Humanities; Medicine; Psychology
2,024
40,443,087
Maternal and perinatal outcomes of birth center births compared to planned home births: A nation-wide, propensity-matched analysis.
The journal of obstetrics and gynaecology research
J Obstet Gynaecol Res
51
6
10.1111/jog.16329
eng
2,025
6
null
null
null
null
[AIMS] Rates of community births, including home and birth center births, have steadily increased in recent decades. Safety outcomes of community births have primarily been compared to hospital births. This study compares maternal and infant morbidity between birth centers and home births in the United States. [METHODS...
birth center; complications; home birth
0.586
68
Medicine; Obstetrics and Gynecology
Medicine
2,024
40,442,801
DNA barcoding of Culicoides biting midges (Diptera: Ceratopogonidae) and detection of Leishmania and other trypanosomatids in southern Thailand.
Parasites vectors
Parasit Vectors
18
1
10.1186/s13071-025-06812-0
eng
2,025
5
29
2,025
5
29
[BACKGROUND] Biting midges of the genus Culicoides play an important role in the transmission of pathogenic arboviruses and parasites. Thailand has documented more than 100 species of Culicoides; however, several cryptic species complexes remain to be clarified. Recent studies in areas with leishmaniasis indicate that ...
COI gene; Culicoides biting midges; Leishmania martiniquensis; Leishmania orientalis; Thailand
null
null
null
null
null
40,442,630
The relative validity of the updated Menzies Remote Short-Item Dietary Assessment Tool (MRSDAT) for use with remote Aboriginal and Torres Strait Islander children and adults.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-23233-x
eng
2,025
5
29
2,025
5
29
[BACKGROUND] This study aimed to determine the relative validity of dietary quality index scores estimated using the updated version of the Menzies Remote Short-item Dietary Assessment Tool (MRSDAT), a food frequency questionnaire developed for use with remote Indigenous communities in Australia. [METHODS] This validat...
Australia; Diet; Dietary assessment; First Nations; Food; Indigenous; Public health; Questionnaire
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,442,616
Comparison of non-intubated and intubated video-assisted thoracoscopic surgery for perioperative complications-a systematic review and meta-analysis.
BMC anesthesiology
BMC Anesthesiol
25
1
10.1186/s12871-025-03154-3
eng
2,025
5
29
2,025
5
29
[BACKGROUND] Non-intubated video-assisted thoracic surgery (NIVATS) avoids lung injury and intubation-related complications from mechanical ventilation, but the intraoperative safety and postoperative recovery quality of NIVATS remain controversial. Consequently, we systematically assessed the viability and safety of n...
Length of hospital stay; Meta-analysis; Non-intubated anesthesia; PPCs; Thoracic surgery; VATS
0.753
58
Anesthesiology and Pain Medicine
Medicine
2,024
40,442,349
Assessment measures for chemotherapy-induced peripheral neuropathy among pediatric oncology patients: an updated systematic review.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
33
6
10.1007/s00520-025-09515-5
eng
2,025
5
29
2,025
5
29
[OBJECTIVE] To update the systematic review of assessment tools on chemotherapy-induced peripheral neuropathy (CIPN) for pediatric oncology patients based on the evidence available after the published review in 2020. [DATA SOURCES] Seven English-language databases (PubMed, CINAHL, PsycINFO, EMBASE, the Cochrane Central...
Assessment measure; Chemotherapy-induced peripheral neuropathy; Pediatric oncology; Systematic review
1.109
143
Oncology; Rehabilitation; Oncology
Medicine; Nursing
2,024
40,441,877
Pregnant patients requiring emergency general surgery: a scoping review of diagnostic and management strategies.
Canadian journal of surgery. Journal canadien de chirurgie
Can J Surg
68
3
10.1503/cjs.001124
eng
2,025
null
null
2,025
5
29
[BACKGROUND] About 1%-2% of pregnant patients develop conditions that require emergency general surgery (EGS). The diagnosis and management of these conditions can be challenging, as surgeons must carefully balance the needs of the pregnant patient and the developing fetus. We sought to summarize the latest literature ...
null
null
null
null
null
null
40,441,597
Ferulic acid methylester improves the comorbidity of insomnia and anxiety in a rat model of PCPA-induced sleep disorder by activating DRN 5-HT neurons.
Neuroscience letters
Neurosci Lett
859-861
null
10.1016/j.neulet.2025.138276
eng
2,025
7
13
2,025
5
27
[OBJECTIVE] Previous studies have indicated that ferulic acid possesses sedative and hypnotic functions. As a derivative of ferulic acid, ferulic acid methylester (FAM) exhibits stronger activity and lower toxicity than ferulic acid. This study is intended to establish a rat model of insomnia induced by PCPA, with the ...
5-hydroxytryptamine neurons; Anxiety; Dorsal raphe nucleus; Ferulic acid methylester; Insomnia
0.766
194
Neuroscience
Neuroscience
2,024
40,441,040
Turmerone-loaded nanocarriers effectively induced apoptosis and attenuated cancerous phenotype inin vitroandin vivoHCC models.
Colloids and surfaces. B, Biointerfaces
Colloids Surf B Biointerfaces
254
null
10.1016/j.colsurfb.2025.114830
eng
2,025
10
null
2,025
5
27
[BACKGROUND] Hepatocellular carcinoma (HCC) still has a high mortality rate and an increasing prevalence trend. Therefore, improving treatment methods is essential for the management of this cancer. Turmerones, which are the main volatile natural components of Curcuma longa Linn, have shown a number of beneficial biolo...
Apoptosis; Drug delivery; Hepatocellular carcinoma; Niosome; Turmerone
null
null
null
null
null
40,440,787
An international survey on withdrawing the ketogenic diet therapy for epilepsy.
Epilepsy behavior : EB
Epilepsy Behav
171
null
10.1016/j.yebeh.2025.110481
eng
2,025
5
28
2,025
5
28
[BACKGROUND] While initiation and maintenance guidelines for ketogenic diet therapies (KDT) are well established, evidence guiding KDT discontinuation remains limited. We aim to explore practices surrounding KDT weaning and identify key factors influencing clinical decisions. [METHODS] An online 24-question survey was ...
Drug Resistant Epilepsy; Epilepsy; Ketogenic diet; Survey; Weaning
null
null
null
null
null
40,440,704
Maternal Immunization With RSVpreF Vaccine: Effectiveness in Preventing Respiratory Syncytial Virus-associated Hospitalizations in Infants Under 6 Months in Argentina: Multicenter Case-control Study.
The Pediatric infectious disease journal
Pediatr Infect Dis J
null
null
10.1097/INF.0000000000004878
eng
2,025
5
28
2,025
5
28
[BACKGROUND] Respiratory syncytial virus (RSV) is a leading cause of morbidity and mortality in infants, particularly in those under 6 months. Starting March 2024, Argentina implemented the bivalent RSVpreF vaccine for pregnant women between 32.0 and 36.6 weeks of gestation during the RSV season. This report study aime...
effectiveness; hospitalization; infants; maternal immunization; respiratory syncytial virus
0.784
160
Pediatrics, Perinatology and Child Health; Infectious Diseases; Microbiology
Medicine
2,024
40,440,515
An Exercise Intervention May Counteract the Degradation of Nerve Conduction from Age-Related Disuse.
Medicine and science in sports and exercise
Med Sci Sports Exerc
null
null
10.1249/MSS.0000000000003767
eng
2,025
5
29
2,025
5
29
[PURPOSE] The purpose was two-fold: first, to determine the effects of resistance training on nerve conduction velocity (NCV), and second, to determine if changes in NCV are dependent on age. We hypothesized that training would result in faster nerve conduction in both young and older adults, albeit to a lesser extent ...
AGING; MOTOR NERVE CONDUCTION VELOCITY; NERVE DETERORIATION; RESISTANCE TRAINING
1.442
271
Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; Sports Science
Health Professions; Medicine
2,024
40,440,465
Social Defeat and Psychosis in the United States: A Replication and Critical Reconceptualization.
Schizophrenia bulletin
Schizophr Bull
null
null
10.1093/schbul/sbaf081
eng
2,025
5
29
2,025
5
29
[BACKGROUND AND HYPOTHESIS] The social defeat hypothesis posits that exclusion and discrimination experienced by socially marginalized populations predict psychotic experiences (PEs), particularly when perceived as defeatist. However, its emphasis on individual-level factors may obscure the role of structural and syste...
discrimination; exclusion; police violence; psychotic experiences; structural racism; systemic inequity
2.138
228
Psychiatry and Mental Health
Medicine
2,024
40,439,954
Real-Life Growth Hormone Treatment Patterns in Children from China: A Report from Two Databases.
Advances in therapy
Adv Ther
42
7
10.1007/s12325-025-03204-9
eng
2,025
7
null
2,025
5
29
[INTRODUCTION] Although recombinant human growth hormone (rhGH) treatment has been established in China for many years for treating short stature (SS), there exists a lacuna on the current status and potential problems associated with effective usage of rhGH. The objective of this study is to investigate the real-world...
Growth hormone; Growth hormone deficiency; Idiopathic short stature; Recombinant human growth hormone; Small for gestational age
1.236
89
Medicine; Pharmacology
Medicine
2,024
40,439,269
A Qualitative Study of Collegiate Student-Athlete Experiences of Recovery After Concussion.
The Journal of head trauma rehabilitation
J Head Trauma Rehabil
null
null
10.1097/HTR.0000000000001067
eng
2,025
5
15
2,025
5
15
[OBJECTIVE] Social and cultural dynamics surrounding expectations of athletes may influence recovery after sport-related concussion. Qualitative investigations narrowly focus on reporting, or specific age groups or sports. We explore how collegiate student-athletes experience concussion recovery; manage diagnosis, symp...
interviews; qualitative research; recovery; sport-related concussion; symptoms
0.944
119
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation; Neurology
Health Professions; Medicine
2,024
40,438,983
Germline PARN Variants in Telomere Biology Disorders and Challenges in Variant Curation.
Molecular genetics genomic medicine
Mol Genet Genomic Med
13
6
10.1002/mgg3.70107
eng
2,025
6
null
null
null
null
[BACKGROUND] PARN encodes poly(A)-specific ribonuclease, a 3 exoribonuclease important in regulating RNA stability and maturation. Rare germline PARN variants have been reported in telomere biology disorders (TBDs) leading to its inclusion on gene panels for bone marrow failure syndromes and pulmonary diseases. [METHOD...
PARN; dyskeratosis congenita; germline variant; telomere; telomere biology disorder; variant curation
null
null
null
null
null
40,438,744
E-learning success evaluation in Lebanon during wartime: An extension of Delone and McLean IS success model.
F1000Research
F1000Res
14
null
10.12688/f1000research.163914.1
eng
2,025
null
null
2,025
4
28
[BACKGROUND] In the fast-paced digital world, e-learning has become the most convenient medium for higher education institutions to provide scalable education. It is used to provide a flexible educational process through the employment of new technologies. Due to the impact of the war on education in Lebanon during fal...
Delone and Mclean; E-learning; Lebanon; higher education; information system.; learning outcomes; war
0.537
119
Arts and Humanities; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Library and Information Sciences; Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
Arts and Humanities; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
2,024
40,438,436
Prevalence of Visual Impairment and Associated Factors among Adult Glaucoma Patients Attending Tertiary Eye Care Center in Gondar, Ethiopia, 2022.
Ethiopian journal of health sciences
Ethiop J Health Sci
34
6
10.4314/ejhs.v34i6.11
eng
2,024
11
null
null
null
null
[BACKGROUND] Glaucoma is a group of eye diseases characterized by damage to the optic nerve, often associated with increased intraocular pressure. Untreated damage from glaucoma can cause irreversible vision loss, making it one of the leading global causes of blindness. This study aimed to determine the prevalence of v...
Adult; Ethiopia; Glaucoma; Gondar; Visual impairment
null
null
null
null
null
40,438,357
Retinal and choroidal blood flow changes in dialysis patients assessed by wide-field swept-source optical coherence tomography angiography.
Frontiers in medicine
Front Med (Lausanne)
12
null
10.3389/fmed.2025.1524503
eng
2,025
null
null
2,025
5
14
[PURPOSE] The study utilized wide-field swept-source optical coherence tomography angiography (SS-OCTA) to examine the alterations in retinal and choroidal blood flow in patients with end-stage renal disease (ESRD) before and after hemodialysis. [METHODS] Forty-two eyes of 24 participants with end-stage renal disease w...
blood flow; choroid; hemodialysis; perfusion area
0.962
102
Medicine
Medicine
2,024
40,438,330
Validation of the Hebrew version of the Community Assessment of Psychic Experiences in a sample of Israeli Hebrew speakers.
Frontiers in psychiatry
Front Psychiatry
16
null
10.3389/fpsyt.2025.1548310
eng
2,025
null
null
2,025
5
14
[INTRODUCTION] The Community Assessment of Psychic Experiences (CAPE-42) is a reliable tool to assess psychotic experiences (PEs) in clinical and non-clinical populations, in research and clinical settings. [METHODS] To investigate cultural differences in PEs and control for pathological behavior in non-clinical groups...
CAPE-42; Hebrew; cross-validation; psychometric properties; psychosis
1.192
134
Psychiatry and Mental Health
Medicine
2,024
40,437,987
Early net ultrafiltration thresholds and mortality in critically ill patients with septic acute kidney injury receiving continuous renal replacement therapy.
Renal failure
Ren Fail
47
1
10.1080/0886022X.2025.2511277
eng
2,025
12
null
2,025
5
29
[BACKGROUND] Net ultrafiltration (NUF) rates correlate with outcomes in critically ill patients on continuous renal replacement therapy (CRRT), but optimal strategies for septic acute kidney injury (AKI) are unclear. This study evaluated early NUF rates and survival in septic AKI. [METHODS] A retrospective cohort of 21...
Net ultrafiltration; acute kidney injury; continuous renal replacement therapy; sepsis
0.84
69
Nephrology; Critical Care and Intensive Care Medicine; Medicine
Medicine
2,024
40,437,855
Meta-Analysis of Thermal Versus Pulse Field Ablation for Pulmonary Vein Isolation Durability in Atrial Fibrillation: Insights From Repeat Ablation.
Clinical cardiology
Clin Cardiol
48
6
10.1002/clc.70151
eng
2,025
6
null
null
null
null
[PURPOSE] Pulsed field ablation (PFA) represents an innovative technique for pulmonary vein isolation (PVI), exhibiting promising efficacy and safety in initial clinical studies. However, the long-term durability of PVI and reconnection patterns following PFA are not as well-characterized compared to those associated w...
PVI durability; atrial fibrillation; pulsed field ablation; thermal ablation
0.83
89
Cardiology and Cardiovascular Medicine; Medicine
Medicine
2,024
40,437,721
Mild cognitive impairment and its associated factors amongst the older people attending government health clinics in Kuantan.
The Medical journal of Malaysia
Med J Malaysia
80
3
null
eng
2,025
5
null
null
null
null
[INTRODUCTION] Malaysia is undergoing a demographic transition towards an aging population, resulting in an anticipated rise in the number of older individuals at risk of developing dementia. Mild cognitive impairment (MCI) represents an intermediate clinical stage between normal cognition and dementia, characterized b...
null
null
null
null
null
null
40,437,616
Analysis of clinical characteristics and risk factors for Staphylococcus aureus disseminated infection secondary to acute osteoarticular infections in children.
Italian journal of pediatrics
Ital J Pediatr
51
1
10.1186/s13052-025-02007-6
eng
2,025
5
28
2,025
5
28
[BACKGROUND] The aim of this study was to investigate the risk factors associated with Staphylococcus aureus (S. aureus) disseminated infection (DSAI) that occurs secondarily to acute osteoarticular infections (OAI) in children. [METHODS] A retrospective analysis of 131 pediatric patients with acute OAI (July 2012-Marc...
Staphylococcus aureus; Children; Disseminated infection; Osteoarticular infection; Osteomyelitis
0.836
65
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,437,569
Transphobia in the United Kingdom: a public health crisis.
International journal for equity in health
Int J Equity Health
24
1
10.1186/s12939-025-02509-z
eng
2,025
5
28
2,025
5
28
[BACKGROUND] The moral panic surrounding trans, non-binary, and gender diverse (TGD) lives in the United Kingdom (UK) has been incited by high-level political and government actors and exacerbated by pervasive misinformation in social and press media. This hostile environment contributes to increasing interpersonal vio...
Hate crime; Healthcare access; Minority stress; Non-binary; Public health; Public health crisis; Transgender; Transphobia; United Kingdom
1.707
93
Health Policy; Public Health, Environmental and Occupational Health
Medicine
2,024
40,437,528
Effects of ammonia exposure on the expression of IL-1β, CRH, and lep-a1 genes in common carp (Cyprinus carpio).
BMC veterinary research
BMC Vet Res
21
1
10.1186/s12917-025-04749-1
eng
2,025
5
28
2,025
5
28
[BACKGROUND] Common carp is one of the most economically important freshwater fish species globally. Ammonia exposure, a frequent challenge in aquaculture, can lead to significant economic losses. This study investigated the impact of un-ionized ammonia (UIA) exposure on the expression profiles of three key genes in co...
Cyprinus carpio; Leptin; Pro-inflammatory cytokines; RT-qPCR; Stress response; Un-ionized ammonia
0.723
86
Veterinary; Medicine
Medicine; Veterinary
2,024
40,437,523
Co-inhibition of Notch1 and ChK1 triggers genomic instability and melanoma cell death increasing the lifespan of mice bearing melanoma brain metastasis.
Journal of experimental clinical cancer research : CR
J Exp Clin Cancer Res
44
1
10.1186/s13046-025-03411-w
eng
2,025
5
28
2,025
5
28
[BACKGROUND] Melanoma brain metastases (MBM) are a leading cause of death in patients with advanced disease. MBM treatment relay on targeted and immunotherapy and on stereotactic radiosurgery as gold standard. Life expectancy has improved significantly with these therapies however, targeted therapy is short lived and o...
Anti-Notch1 antibody; ChK1 inhibition; DNA damage; Genomic instability; Melanoma brain metastases
null
null
null
null
null
40,437,464
Suture lasso combined with lateral plate in comminuted transolecranon fracture-dislocations of the elbow.
BMC surgery
BMC Surg
25
1
10.1186/s12893-025-02972-z
eng
2,025
5
28
2,025
5
28
[OBJECTIVE] The objective of this study was to evaluate the effectiveness of suture lasso combined with lateral plate in comminuted transolecranon fracture-dislocations of the elbow. [METHOD] We retrospectively reviewed 13 patients with comminuted transolecranon fracture-dislocations of the elbow. Our study included 6 ...
Comminuted fracture of proximal ulna; Coronoid fracture; Lateral plate; Suture Lasso; Transolecranon fracture-dislocations
0.572
64
Medicine; Surgery
Medicine
2,024
40,437,370
Single-cell data combined with phenotypes improves variant interpretation.
BMC genomics
BMC Genomics
26
1
10.1186/s12864-025-11711-w
eng
2,025
5
28
2,025
5
28
[BACKGROUND] Whole genome sequencing offers significant potential to improve the diagnosis and treatment of rare diseases by enabling the identification of thousands of rare, potentially pathogenic variants. Existing variant prioritisation tools can be complemented by approaches that incorporate phenotype specificity a...
Interpretable models; Machine learning; Random forest; Rare disease; Variant prioritisation; Whole Genome sequencing
1.003
208
Biotechnology; Genetics
Biochemistry, Genetics and Molecular Biology
2,024
40,437,362
TcMYB73, a salicylic acid-responsive R2R3-MYB transcription factor, positively regulates paclitaxel biosynthesis in Taxus chinensis in direct and indirect ways.
BMC plant biology
BMC Plant Biol
25
1
10.1186/s12870-025-06755-9
eng
2,025
5
28
2,025
5
28
[BACKGROUND] Paclitaxel (Taxol) is an invaluable secondary metabolite extracted from Taxus species, wildly utilized in cancer therapeutics. Salicylic acid (SA), an important phytohormone, substantially elevates paclitaxel accumulation in Taxus cell suspension cultures. However, the molecular mechanisms governing SA-ind...
Paclitaxel biosynthesis; R2R3-MYB transcription factor; Salicylic acid signal; Taxus chinensis; TcWRKY33
1.134
159
Plant Science
Agricultural and Biological Sciences
2,024
40,437,308
Visual field outcomes after cataract surgery with or without microinvasive glaucoma surgery in open-angle glaucoma: a systematic review and meta-analysis of RCTs reporting visual field results.
International ophthalmology
Int Ophthalmol
45
1
10.1007/s10792-025-03579-2
eng
2,025
5
28
2,025
5
28
[PURPOSE] To compare the benefits of combining microinvasive glaucoma surgery (MIGS) with cataract surgery (CS) for visual field (VF) preservation in patients with primary open-angle glaucoma (POAG) and coexisting cataracts. [METHODS] A systematic review and meta-analysis were conducted on randomised controlled trials ...
Cataract surgery; Glaucoma; MIGS; Microinvasive glaucoma surgery; Visual field
0.642
57
Ophthalmology
Medicine
2,024
40,436,732
Bacterial load comparison of enteroaggregative Escherichia coli (EAEC) by real-time PCR (qPCR) between children with diarrhea and asymptomatic infection.
Enfermedades infecciosas y microbiologia clinica (English ed.)
Enferm Infecc Microbiol Clin (Engl Ed)
null
null
10.1016/j.eimce.2025.05.003
eng
2,025
5
27
2,025
5
27
[INTRODUCTION] Enteroaggregative Escherichia coli (EAEC) is a pathotype of diarrheagenic E. coli (DEC) that causes acute and persistent diarrhoea in children, HIV-infected patients and travelers. However, EAEC can also be isolated in people without diarrhoea. The aim of this study was to evaluated if the EAEC bacterial...
Diarrhea and asymptomatic infection; EAEC; qPCR
0.337
49
Infectious Diseases; Microbiology; Microbiology
Immunology and Microbiology; Medicine
2,024
40,436,455
Functional vision tests as clinical trial outcome measures in ophthalmology: a scoping review.
BMJ open
BMJ Open
15
5
10.1136/bmjopen-2024-097970
eng
2,025
5
27
2,025
5
27
[OBJECTIVES] To identify currently available functional vision tests and evaluate their use as clinical trial outcome measures in ophthalmology. [DESIGN] Scoping review using the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-analysis Extension for Scoping Reviews) guidelines. [METHODS] A literat...
Clinical Trial; GENETICS; OPHTHALMOLOGY
1.016
176
Medicine
Medicine
2,024
40,436,214
Feilike mixture targeting the STAT1-NLRP3 axis represses the pyroptosis of epithelial cells to alleviate Mycoplasma pneumoniae pneumonia.
Microbial pathogenesis
Microb Pathog
206
null
10.1016/j.micpath.2025.107754
eng
2,025
9
null
2,025
5
26
[BACKGROUND] Mycoplasma pneumoniae (MP) is one of the most important pathogens causing respiratory tract infections in children. Feilike mixture (FLKM), as a classical traditional Chinese medicine serving as an ancillary treatment for pneumonia, has not yet been fully elucidated regarding its specific mechanisms in dis...
Feilike mixture; Mycoplasma pneumoniae pneumonia; NLRP3; Pyroptosis; STAT1
0.825
107
Infectious Diseases; Microbiology
Immunology and Microbiology; Medicine
2,024
40,435,878
The Predictive Value of Basic Laparoscopic Evaluations on Complex Cases Using the Society for Improving Medical Procedural Learning Database.
The Journal of surgical research
J Surg Res
311
null
10.1016/j.jss.2025.04.041
eng
2,025
7
null
2,025
5
27
[INTRODUCTION] The transference of technical skills from basic to complex procedures is assumed-but untested-during training and board certification. We examine whether resident performance on frequently performed, basic laparoscopic procedures can predict performance on their first complex laparoscopic procedure. [MET...
Competency-based medical education; Component skills; Entrustable professional activities; Machine learning; Surgical education
0.736
131
Surgery
Medicine
2,024
40,435,590
Comparative Evaluation of analgesic efficacy of ketamine and magnesium sulfate as adjuvants to bupivacaine for scalp block in supratentorial Craniotomy: A Randomized, Double-Blind clinical study.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
J Clin Neurosci
137
null
10.1016/j.jocn.2025.111347
eng
2,025
7
null
2,025
5
27
[BACKGROUND] Effective pain management during craniotomy is crucial for optimizing hemodynamics, recovery, and patient satisfaction. This study evaluated the efficacy of ketamine and magnesium sulfate as adjuvants to bupivacaine in preemptive scalp blocks, focusing on hemodynamics, postoperative pain, and analgesic con...
Adjuvants; Analgesia; Craniotomy; Ketamine; Magnesium sulfate; Scalp block
0.654
104
Medicine; Surgery; Neurology; Neurology; Physiology
Medicine; Neuroscience
2,024
40,485,085
Esthetic Outcome of a Universal Shade Resin Composite Placed Before Nonvital Tooth Bleaching.
Operative dentistry
Oper Dent
50
3
10.2341/24-099-T
eng
2,025
5
1
null
null
null
[OBJECTIVE] In this case report, we describe the use of a universal shade resin composite to restore a discolored tooth before nonvital tooth bleaching. The intent of this procedure is to maintain an acceptable color match, eliminating the need for subsequent replacement of the restoration after bleaching. [METHODS] A ...
null
0.714
96
Dentistry; Medicine
Dentistry; Medicine
2,024
40,485,056
Cognitive and Emotional Health in Long COVID: a Cross-Sectional Study in Brazil.
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists
Arch Clin Neuropsychol
null
null
10.1093/arclin/acaf054
eng
2,025
6
9
2,025
6
9
[OBJECTIVE] Long COVID is characterized by persistent symptoms following a COVID-19 infection, including cognitive and emotional impairment. Brazil has one of the highest rates of COVID-19 infections globally, but there are still few studies assessing the long-term impact of the disease on mental health in this populat...
Brazil; COVID-19; Cognitive deficits; Emotion; Long COVID; Neuropsychological assessment
0.715
119
Clinical Psychology; Medicine; Neuropsychology and Physiological Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
40,484,783
Baseline CT-derived tumor burden and liquid biopsy as biomarkers to predict survival in patients with metastatic solid cancer.
Diagnostic and interventional imaging
Diagn Interv Imaging
null
null
10.1016/j.diii.2025.06.002
eng
2,025
6
7
2,025
6
7
[PURPOSE] The purpose of this study was to evaluate baseline tumor burden from liquid biopsy (LB) and computed tomography (CT) as prognostic biomarkers and whether their combination refines stratification in metastatic solid cancers. [MATERIALS AND METHODS] This retrospective cohort study included 1065 patients. Eligib...
Biomarkers; Computed tomography; Liquid biopsy; Prognosis; Tumor burden
1.838
63
Medicine; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine
2,024
40,484,780
Combination regimen of intravesical docetaxel, gemcitabine, and cisplatin in patients with BCG-unresponsive bladder cancer: clinical outcomes and genomic correlations.
Urologic oncology
Urol Oncol
null
null
10.1016/j.urolonc.2025.05.012
eng
2,025
6
7
2,025
6
7
[PURPOSE] Approximately 40% of non-muscle invasive bladder cancer patients who are treated with Bacillus Calmette-Guerin will experience treatment failure and recurrence. Many patients either refuse or are medically unfit for radical cystectomy. We aim to determine the efficacy and long-term durability of the novel tri...
BCG; Bladder cancer; Intravesical instillation
0.855
89
Urology; Oncology
Medicine
2,024