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40,620,465
Dose-Dependent Effects of Remimazolam on Early Perioperative Neurocognitive Disorders in Elderly Colorectal Cancer Patients Undergoing Laparoscopic Surgery.
Drug design, development and therapy
Drug Des Devel Ther
19
null
10.2147/DDDT.S502910
eng
2,025
null
null
2,025
6
30
[OBJECTIVE] To study the effect of different doses of remimazolam on the maintenance of anesthesia and its impact on postoperative cognitive function in elderly patients undergoing laparoscopic colorectal surgery. [METHODS] A total of 120 elderly patients scheduled for laparoscopic colorectal surgery under general anes...
cognitive function; elderly; general anesthesia; remimazolam
1.19
108
Drug Discovery; Pharmaceutical Science; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,024
40,620,436
Electroacupuncture superiority in knee osteoarthritis: a meta-analysis of four acupuncture techniques.
Frontiers in medicine
Front Med (Lausanne)
12
null
10.3389/fmed.2025.1563715
eng
2,025
null
null
2,025
6
20
[BACKGROUND] Knee osteoarthritis is the most prevalent chronic joint disease affecting persons 50 years, which significantly impairs the patients' lives. Although acupuncture can treat knee osteoarthritis; none of the studies have compared the effectiveness of four common acupuncture techniques (electroacupuncture, fil...
acupuncture; body mass index; electroacupuncture; knee osteoarthritis; systematic review
0.962
102
Medicine
Medicine
2,024
40,620,331
Evaluation of immunization service delivery in primary healthcare centers in Akinyele and Lagelu local government areas, Oyo State, Nigeria.
SAGE open medicine
SAGE Open Med
13
null
10.1177/20503121251352974
eng
2,025
null
null
2,025
7
3
[INTRODUCTION] Primary healthcare is the most accessible and affordable form of healthcare for Nigerians. It offers primary prevention strategies such as routine immunization. Routine immunization at government facilities, including primary healthcares, is provided free of charge under Nigeria's Expanded Program on Imm...
Immunization service delivery; Nigeria; cold chain management; healthcare workers; primary healthcare
0.668
41
Medicine
Medicine
2,024
40,619,663
Antioxidant and Cytotoxic Activity of the Aporphine Alkaloid (Boldine) Against DMH-induced Colorectal Carcinogenesis in Wistar Rats: An In silico, In vitro, and In vivo study.
Medicinal chemistry (Shariqah (United Arab Emirates))
Med Chem
null
null
10.2174/0115734064358287250613065507
eng
2,025
7
3
2,025
7
3
[OBJECTIVE] The objective of this study is to investigate the role of the aporphine alkaloid boldine as a potential inhibitor of specific protein targets involved in colorectal cancer, using in silico docking and molecular dynamics simulation studies, and to evaluate its therapeutic potential in modulating the patholog...
in silico; Colorectal cancer; antioxidant.; boldine; cytotoxicity
null
null
null
null
null
40,619,481
Multiparameter pancreatic parenchyma assessment using Dual-layer Spectral-detector CT for postpancreatectomy acute pancreatitis prediction.
Abdominal radiology (New York)
Abdom Radiol (NY)
null
null
10.1007/s00261-025-05093-6
eng
2,025
7
7
2,025
7
7
[BACKGROUND] Post-pancreatectomy acute pancreatitis (PPAP) has been increasingly recognized as an independent complication since its formal definition by the International Study Group for Pancreatic Surgery (ISGPS) in 2022. This study aimed to evaluate the diagnostic accuracy of multiparameter assessment of pancreatic ...
Complications; Computed tomography; Dual layer detector; Pancreaticoduodenectomy; Pancreatitis
0.817
91
Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging; Urology; Gastroenterology
Health Professions; Medicine
2,024
40,619,219
Evaluation of Anthracycline-Induced Cardiotoxicity Using Proton Magnetic Resonance Spectroscopy Compared With Cardiac Functional Parameters - An Animal Study.
Circulation journal : official journal of the Japanese Circulation Society
Circ J
null
null
10.1253/circj.CJ-25-0108
eng
2,025
7
4
2,025
7
4
[BACKGROUND] Anthracycline-induced cardiotoxicity (AIC) poses significant challenges due to its severe adverse effects, limiting the use of anthracycline drugs (ATC). Early detection and intervention are pivotal, yet current diagnostic methods lack sensitivity. [METHODS AND RESULTS] In a prospective animal study, 20 ra...
Cardiotoxicity; Lipids; Magnetic resonance imaging; Proton magnetic resonance spectroscopy
null
null
null
null
null
40,619,056
Neurosurgical Resident Skill Development Using a Novel Simulator-Based Anterior Cervical Discectomy and Fusion Curriculum.
World neurosurgery
World Neurosurg
201
null
10.1016/j.wneu.2025.124257
eng
2,025
7
4
2,025
7
4
[BACKGROUND] Simulation-based training is increasingly integrated into surgical education as a method to enhance technical skills in a safe and reproducible environment. This dual-institution pilot study - conducted within the neurosurgery residency programs at Massachusetts General Hospital and Stanford University - e...
Education; Neurosurgery; Simulation; Spaced repetition; Surgical training; Technical skills
0.709
123
Neurology; Surgery
Medicine
2,024
40,618,795
Closing the gap: Early experience from a new Endovascular Thrombectomy service in regional and rural North Queensland, Australia.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
J Stroke Cerebrovasc Dis
34
9
10.1016/j.jstrokecerebrovasdis.2025.108390
eng
2,025
9
null
2,025
7
5
[BACKGROUND] Endovascular clot retrieval is the standard of care for acute ischemic stroke caused by large vessel occlusion. However, access to mechanical thrombectomy remains limited in rural and regional areas, where patients often require transfer to urban centres. These delays are directly associated with poorer cl...
Acute ischemic stroke; Endovascular clot retrieval treatment; Interhospital transfer; Mechanical thrombectomy; Regional and Rural stroke care
0.688
85
Rehabilitation; Cardiology and Cardiovascular Medicine; Neurology; Surgery
Medicine
2,024
40,618,745
Pharmacokinetics-driven individualized detoxification procedure in patients dependent on benzodiazepines and other GABA-A receptor modulators.
European addiction research
Eur Addict Res
null
null
10.1159/000547221
eng
2,025
7
5
2,025
7
5
[INTRODUCTION] Despite extreme inter-patient differences in the benzodiazepine (BZD) metabolism rate, patients dependent on BZDs or other GABA-A receptor modulators are treated without laboratory control. The proposed detoxification method is the first to employ concentration feedback to prevent routinely unrecognized ...
null
0.981
64
Health; Medicine; Psychiatry and Mental Health
Medicine; Social Sciences
2,024
40,618,638
Preoperative risk stratification for multifocal intrahepatic cholangiocarcinoma after liver resection: a multicenter analysis with CART model.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Eur J Surg Oncol
51
9
10.1016/j.ejso.2025.110277
eng
2,025
6
24
2,025
6
24
[BACKGROUND AND AIM] The prognostic significance of liver resection for multifocal intrahepatic cholangiocarcinoma (ICC) remains controversial and is further complicated by the lack of reliable predictive models. This study aims to develop a prognostic Classification and Regression Tree (CART) model for resectable mult...
Classification and regression tree; Intrahepatic cholangiocarcinoma; Multifocal; Prognosis; Resectable
1.153
123
Medicine; Surgery; Oncology
Medicine
2,024
40,618,530
The effects of rTMS and tDCS on repetitive/stereotypical behaviors, cognitive/executive functions in intellectually capable children and young adults with autism spectrum disorder: A systematic review and meta-analysis of randomized controlled trials.
Research in developmental disabilities
Res Dev Disabil
164
null
10.1016/j.ridd.2025.105076
eng
2,025
7
5
2,025
7
5
[OBJECTIVE] This study aims to evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) on repetitive/stereotypical behaviors and cognitive/executive functions in children and young adults with intellectually capable autism spectrum disorder (IC-ASD...
Autism; Brain Stimulation; Children and Young Adults; Repetitive Transcranial Magnetic Stimulation; Transcranial Direct Current Stimulation
0.9
117
Clinical Psychology; Developmental and Educational Psychology
Psychology
2,024
40,618,313
Comparison of single and double stapling anastomosis in restorative surgery for ulcerative colitis: short- and long-term outcomes and functional results.
Updates in surgery
Updates Surg
null
null
10.1007/s13304-025-02294-y
eng
2,025
7
6
2,025
7
6
[BACKGROUND] Ulcerative colitis (UC) often requires surgery, with restorative proctocolectomy and ileal pouch-anal anastomosis (IPAA) considered the standard treatment. While the double-stapled (DS-IPAA) anastomotic technique remains commonly used, single-stapled (SS-IPAA) techniques, including transanal IPAA (ta-IPAA)...
Functional outcomes; Laparoscopic surgery of IBD; Outcomes in pouch surgery; Pouch surgery; Ulcerative colitis
0.787
44
Surgery
Medicine
2,024
40,618,138
Non-invasive neurally adjusted ventilatory assist versus nasal continuous positive airway pressure for premature infants: a systematic review and meta-analysis.
European journal of medical research
Eur J Med Res
30
1
10.1186/s40001-025-02803-0
eng
2,025
7
5
2,025
7
5
[OBJECTIVE] The purpose of this study was to compare the benefits of non-invasive neurally adjusted ventilatory assist (NIV-NAVA) versus Nasal continuous positive airway pressure (NCPAP) as respiratory support for premature infants. [METHODS] Literature on NIV-NAVA and NCPAP as respiratory support of premature infants ...
Meta-analysis; Nasal continuous positive airway pressure; Non-invasive neurally adjusted ventilatory assist; Premature infants
null
70
Medicine
Medicine
2,024
40,618,110
A two-sample Mendelian randomization study of atrial fibrillation screening, risk factor analysis, and serum uric acid levels.
Journal of cardiothoracic surgery
J Cardiothorac Surg
20
1
10.1186/s13019-025-03448-0
eng
2,025
7
5
2,025
7
5
[BACKGROUND] It aimed to explore the relationship between atrial fibrillation (AF) screening, risk factor analysis, and serum uric acid (UA) levels. By analyzing the results of AF screening and risk factors, the potential impact of serum UA levels on AF risk was further investigated. [METHODS] The study population cons...
Atrial fibrillation; MR study; Risk factors; Serum UA levels
0.485
61
Surgery; Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine
Medicine
2,024
40,617,510
Maternal Hemoglobin Concentrations in Early and Late Pregnancy and Adverse Birth Outcomes: A Nationwide Cohort Study in Sri Lanka.
The Journal of nutrition
J Nutr
null
null
10.1016/j.tjnut.2025.06.029
eng
2,025
7
3
2,025
7
3
[BACKGROUND] Maternal hemoglobin (Hb) plays a critical role in pregnancy and may influence birth outcomes. [OBJECTIVES] The study aimed to examine associations between maternal Hb in early and late pregnancy and adverse birth outcomes in a cohort of singleton pregnancies in Sri Lanka. [METHODS] This prospective study a...
adverse birth outcomes; anemia; hemoglobin; low birth weight; pregnancy; preterm birth; small-for-gestational age
1.152
306
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
40,617,366
Zhuru extracts ameliorate lipid accumulation of MASLD via suppressing the mTORC1/SREBPs pathway.
Journal of ethnopharmacology
J Ethnopharmacol
352
null
10.1016/j.jep.2025.120246
eng
2,025
8
29
2,025
7
3
[ETHNOPHARMACOLOGICAL RELEVANCE] Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent liver disease worldwide, primarily caused by poor lifestyle choices and dietary habits. Caulis Bambusae In Taenias, commonly known as Zhuru in Chinese, is a traditional Chinese medicinal material from...
Lipid accumulation; Lipid synthesis; Oxidative stress; SREBP1/2; Zhuru; mTORC1
1.142
243
Drug Discovery; Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,024
40,617,195
Women's genital self-images, their acceptance of cosmetic surgery, and evaluation the relationship.
European journal of obstetrics, gynecology, and reproductive biology
Eur J Obstet Gynecol Reprod Biol
312
null
10.1016/j.ejogrb.2025.114557
eng
2,025
8
null
2,025
7
2
[OBJECTIVE] Genital self-image and genital cosmetic surgery are gaining importance and require evaluation. This study examines women's genital self-image, attitudes toward cosmetic surgery, and the relationship between these factors. [STUDY DESIGN] This correlational study was conducted between September 2023 and March...
Cosmetic surgery; Genitalia; Self; Women
null
null
null
null
null
40,617,039
Genital self-mutilation in a schizophrenic patient: A case report.
International journal of surgery case reports
Int J Surg Case Rep
133
null
10.1016/j.ijscr.2025.111587
eng
2,025
8
null
2,025
6
30
[INTRODUCTION] Genital self-mutilation is a rare but severe form of self-inflicted injury, most commonly associated with psychiatric disorders, particularly schizophrenia. It poses significant challenges due to the need for urgent urological intervention and psychiatric stabilization. While self-harming behaviors are f...
Genital self-mutilation; Ischemic necrosis; Microsurgical reimplantation; Penile amputation
0.238
31
Surgery
Medicine
2,024
40,616,485
Associations of White Blood Cell, Platelet Count, Platelet-to-White Blood Cell Ratio with Muscle Mass among Community-Dwelling Older Adults in China.
Biomedical and environmental sciences : BES
Biomed Environ Sci
38
6
10.3967/bes2025.051
eng
2,025
6
20
null
null
null
[OBJECTIVE] This study aimed to evaluate the relationships of white blood cell (WBC) count, platelet (PLT) count, and PLT-to-WBC ratio (PWR) with muscle mass in Chinese older adults. [METHODS] This cross-sectional analysis involved 4,033 Chinese older adults aged ≥ 65 years from the Healthy Ageing and Biomarkers Cohort...
Muscle mass; Older adults; Platelet; Platelet to white blood cell ratio; White blood cell count
null
null
null
null
null
40,616,107
Factors influencing medical insurance participation and satisfaction among non-standard workers in China.
BMC health services research
BMC Health Serv Res
25
1
10.1186/s12913-025-13078-w
eng
2,025
7
5
2,025
7
5
[OBJECTIVES] Universal health coverage is the goal of China's healthcare system reform. However, with the growth of the gig economy, problems such as the failure of non-standard workers to participate in basic medical insurance continue to arise. Consequently, we investigated the factors that influence non-standard wor...
Basic medical insurance; Insurance participation status; Non-standard workers; Satisfaction with insurance policy
1.174
157
Health Policy
Medicine
2,024
40,615,849
The effects of Pranayama breathing exercise on symptom burden among women with breast cancer undergoing chemotherapy: a randomized controlled trial.
BMC complementary medicine and therapies
BMC Complement Med Ther
25
1
10.1186/s12906-025-04981-0
eng
2,025
7
4
2,025
7
4
[BACKGROUND] Pranayama breathing exercises may help reduce the burden of chemotherapy-induced symptoms in women with breast cancer. The aim of this study was to determine the effect of pranayama breathing exercise on symptom burden in women with breast cancer undergoing chemotherapy. [METHODS] In this clinical trial, 7...
Breast cancer; Chemotherapy; Pranayama breathing exercises; Symptom burden; Yoga breathing
0.741
123
Complementary and Alternative Medicine
Medicine
2,024
40,615,822
Undergraduate medical students' perspectives on research education and their confidence in research skills: a cross-sectional study from Palestine.
BMC medical education
BMC Med Educ
25
1
10.1186/s12909-025-07586-w
eng
2,025
7
4
2,025
7
4
[OBJECTIVE] Undergraduate medical research training is fundamental for developing future physicians' research competencies and promoting evidence-based practice. This study aimed to evaluate Palestinian medical students' perspectives on the adequacy of research education and examine their confidence in research skills ...
Confidence; Education; Perspectives; Research skills; Undergraduate medical students
0.947
107
Education; Medicine
Medicine; Social Sciences
2,024
40,615,793
Determinants of cervical cancer screening uptake in Lesotho: evidence from 2024 Demographic and Health Survey data.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-23593-4
eng
2,025
7
4
2,025
7
4
[INTRODUCTION] Cervical cancer affects approximately 13.1 women per 100,000 globally, with its incidence rates varying significantly across regions. Low- and middle-income countries bear the highest burden, partly due to inadequate access to preventive measures, such as regular screening and timely treatment. This stud...
Cervical cancer; Demography and health survey; Lesotho; Screening uptake
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,615,791
The efficacy and safety of antithrombotic therapy in patients undergoing TAVI: a network meta-analysis.
BMC cardiovascular disorders
BMC Cardiovasc Disord
25
1
10.1186/s12872-025-04862-x
eng
2,025
7
4
2,025
7
4
[BACKGROUND] Severe aortic stenosis (SAS) is a critical condition with high morbidity and mortality if left untreated. Transcatheter aortic valve implantation (TAVI) has emerged as a transformative therapy, especially for patients at high or intermediate surgical risk. However, the optimal post-TAVI antithrombotic ther...
Antithrombotic therapy; Bleeding risk; Mortality; Network meta-analysis; Transcatheter aortic valve implantation
0.708
76
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,614,772
Association of Preoperative Nutritional Status With Outcomes in Fronto-Orbital Advancement for Syndromic Craniosynostosis.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
J Oral Maxillofac Surg
null
null
10.1016/j.joms.2025.06.027
eng
2,025
6
17
2,025
6
17
[BACKGROUND] Calvarial vault remodeling (CVR) is a critical procedure for patients with syndromic craniosynostosis (SC), a condition associated with genetic syndromes and comorbidities that can worsen nutritional status before surgery. Despite nutritional challenges in this population, few studies have assessed how pre...
null
0.767
147
Oral Surgery; Otorhinolaryngology; Surgery
Dentistry; Medicine
2,024
40,614,565
Prognostic Value of the Right Ventricular-to-Left Ventricular Volume Ratio in Tricuspid Regurgitation.
JACC. Advances
JACC Adv
4
8
10.1016/j.jacadv.2025.101922
eng
2,025
7
3
2,025
7
3
[BACKGROUND] Tricuspid regurgitation (TR) is associated with right ventricular (RV) remodeling; however, conventional RV metrics may not fully reflect the interplay between the right and left ventricles. [OBJECTIVES] The aim of the study was to examine the prognostic value of the right ventricular-to-left ventricular v...
magnetic resonance imaging; remodeling; right ventricle; tricuspid regurgitation
null
null
null
null
null
40,614,465
Genetic Determinants of Leukocyte Count in Nonsyndromic Cleft Lip With or Without Cleft Palate Among Asians.
International dental journal
Int Dent J
75
5
10.1016/j.identj.2025.100877
eng
2,025
7
3
2,025
7
3
[OBJECTIVES] Previous studies have shown that maternal proinflammatory status could increase the risk of nonsyndromic cleft lip with or without cleft palate (NSCL/P) in offspring. This study aimed to assess the relationship between leukocyte counts and NSCL/P. [METHODS] The NSCL/P genome-wide association study (GWAS) d...
Genetic association studies; Genetics; Inflammation; Mendelian randomization analysis; Orofacial cleft
0.972
81
Dentistry
Dentistry
2,024
40,614,437
BrainAGE latent representation clustering is associated with longitudinal disease progression in early-onset Alzheimer's disease.
Journal of neuroradiology = Journal de neuroradiologie
J Neuroradiol
52
5
10.1016/j.neurad.2025.101365
eng
2,025
7
3
2,025
7
3
[INTRODUCTION] Early-onset Alzheimer's disease (EOAD) population is a clinically, genetically and pathologically heterogeneous condition. Identifying biomarkers related to disease progression is crucial for advancing clinical trials and improving therapeutic strategies. This study aims to differentiate EOAD patients wi...
Brain age gap estimation; Clustering; Magnetic resonance imaging
null
null
null
null
null
40,614,325
Brain microstate features of patients with depression: A transcranial magnetic stimulation and electroencephalographic (TMS-EEG) study.
Psychiatry research
Psychiatry Res
351
null
10.1016/j.psychres.2025.116616
eng
2,025
9
null
2,025
6
29
[BACKGROUND] Recent studies using transcranial magnetic stimulation and electroencephalography (TMS-EEG) have revealed abnormal changes in the temporal and frequency domains associated with depression. In this cross-sectional study, we employed microstate analysis to investigate the spatio-temporal features of TMS-indu...
Depression; Electro-encephalographic; Microstate; Transcranial magnetic stimulation
1.606
187
Biological Psychiatry; Psychiatry and Mental Health
Medicine; Neuroscience
2,024
40,614,297
Evaluating the rigour and application of phenomenological studies in medical radiation science research: A methodological review.
Radiography (London, England : 1995)
Radiography (Lond)
31
5
10.1016/j.radi.2025.103019
eng
2,025
7
3
2,025
7
3
[OBJECTIVES] This review evaluates the methodological rigour of phenomenological studies in medical radiation science (MRS). It examines the frequency and accuracy of phenomenological approaches and provides recommendations to enhance qualitative rigour in future research. [KEY FINDINGS] A systematic search across thre...
Lived experiences; Medical radiation science; Methodological rigour; Phenomenological research; Qualitative methodology
0.654
43
Research and Theory; Assessment and Diagnosis; Radiological and Ultrasound Technology; Radiology, Nuclear Medicine and Imaging
Health Professions; Medicine; Nursing
2,024
40,614,290
Predicting risk of hospitalization among adult home care clients: An international perspective.
Geriatric nursing (New York, N.Y.)
Geriatr Nurs
64
null
10.1016/j.gerinurse.2025.103418
eng
2,025
null
null
2,025
7
3
[PURPOSE] The primary objective of this project was to evaluate hospital admissions among older adult clients following entry into formal home care services and to develop a risk scale to predict hospitalization. [METHODS] Study design was a secondary analysis of data generated from the interRAI Home Care tool using ne...
ED visit risk prediction; Home Care Services; Hospital admission risk prediction; InterRAI
0.914
57
Medicine; Gerontology
Medicine; Nursing
2,024
40,632,680
The productivity loss associated with HPV-related cancer mortality in Europe; years of life lost and productivity costs.
Journal of medical economics
J Med Econ
27
sup2
10.1080/13696998.2025.2528518
eng
2,024
4
null
2,025
7
9
[BACKGROUND] Human Papillomavirus (HPV) is linked to several cancers, including cervical, head and neck, vulval, vaginal, anal, and penile cancer. In 2022, HPV-related cancers accounted for an estimated 67,500 new cases annually across 27 EU states, imposing a humanistic and economic burden. This study estimates produc...
Europe; Health economics; I10; I18; cancer; economic burden; human papillomavirus; indirect costs; vaccines
0.927
58
Health Policy
Medicine
2,024
40,665,192
Remote Ischemic Preconditioning to Prevent Delayed Cerebral Ischemia Due to Vasospasm in the Treatment of Patients with Aneurysmal Subarachnoid Hemorrhage.
Neurocritical care
Neurocrit Care
null
null
10.1007/s12028-025-02324-y
eng
2,025
7
15
2,025
7
15
[BACKGROUND] Remote ischemic preconditioning (RIPC) has shown potential in reducing vasospasm-induced secondary ischemia after aneurysmal subarachnoid hemorrhage (aSAH). Research suggests RIPC may help the brain adapt to periods of reduced blood flow, thereby reducing the risk of cerebral infarction secondary to delaye...
Aneurysm rupture; Aneurysmal subarachnoid hemorrhage; DCI; Delayed cerebral ischemia; RIPC; Remote ischemic preconditioning
1.177
97
Critical Care and Intensive Care Medicine; Neurology
Medicine
2,024
40,665,144
Lifestyle interventions and medication burden in older adults: insights from the Lifestyle Intervention and Independence for Elders (LIFE) and the Sarcopenia and Physical fRailty iN older people: multi-componenT Treatment strategies (SPRINTT) trials.
European geriatric medicine
Eur Geriatr Med
null
null
10.1007/s41999-025-01266-0
eng
2,025
7
15
2,025
7
15
[PURPOSE] Polypharmacy is a growing public health problem and implementing strategies to reduce its prevalence is considered a research and clinical priority. Healthy lifestyle impacts the onset and progression of chronic conditions. Yet, there is limited understanding of how this effect influences medication use. The ...
Lifestyle intervention; Physical activity; Polypharmacy
1.009
45
Gerontology; Geriatrics and Gerontology
Medicine; Nursing
2,024
40,665,137
Comparison of differences in hematogenous metastasis among cervical cancer patients by CT-guided three-tube intracavitary brachytherapy and hybrid intracavitary and interstitial brachytherapy.
Discover oncology
Discov Oncol
16
1
10.1007/s12672-025-03202-x
eng
2,025
7
15
2,025
7
15
[OBJECTIVE] To compare whether CT-guided three-tube intracavitary brachytherapy (ICBT) and hybrid intracavitary with interstitial brachytherapy (IC/ISBT) will cause differences in the hematogenous metastasis of cervical cancer. [METHODS] A retrospective cohort study was conducted to analyze 224 patients in our hospital...
CT guidance; Cervical cancer; Hematogenous metastasis; IC/ISBT; ICBT
0.88
47
Endocrine and Autonomic Systems; Endocrinology; Endocrinology, Diabetes and Metabolism; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
40,664,866
Splanchnic hemodynamic parameters measured with 4D flow MRI can diagnose severe portal hypertension.
European radiology
Eur Radiol
null
null
10.1007/s00330-025-11799-4
eng
2,025
7
15
2,025
7
15
[OBJECTIVES] To assess the diagnostic performance of splanchnic hemodynamic parameters measured with 4D flow MRI for diagnosis of severe portal hypertension (PH; hepatic venous pressure gradient (HVPG) ≥ 12 mmHg), and prediction of liver decompensation in patients with chronic liver disease. [MATERIALS AND METHODS] Our...
Magnetic resonance imaging; Portal hypertension; Splanchnic circulation
1.535
182
Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,664,536
A multimodal lifestyle intervention complemented with epigallocatechin gallate to prevent cognitive decline in APOE- ɛ4 carriers with Subjective Cognitive Decline: a randomized, double-blinded clinical trial (PENSA study).
The journal of prevention of Alzheimer's disease
J Prev Alzheimers Dis
null
null
10.1016/j.tjpad.2025.100271
eng
2,025
7
14
2,025
7
14
[BACKGROUND] The potential of dietary compounds to enhance the effects of multimodal lifestyle interventions (MLIs) on cognition in individuals at high risk of cognitive impairment remains unclear. [OBJECTIVES] To assess whether the addition of a green tea extract enriched with epigallocatechin-3-gallate (EGCG) enhance...
Epigallocatechin-3-gallate; Multimodal lifestyle intervention; Prevention
null
null
null
null
null
40,664,496
Atrial fibrillation and the risk of sudden cardiac death: incidence, impact and implications.
Heart (British Cardiac Society)
Heart
null
null
10.1136/heartjnl-2025-326003
eng
2,025
8
5
2,025
8
5
[BACKGROUND] Atrial fibrillation(AF) may be linked to increased sudden cardiac death (SCD) risk, but patients with AF are often neglected in studies on ECG risk factors for SCD. We aimed to clarify the long-term SCD incidence in AF among patients undergoing coronary angiography. [METHODS] SCD incidence was retrospectiv...
Atrial Fibrillation; Coronary artery disease; Heart Failure; SUDDEN CARDIAC DEATH
1.781
214
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,664,276
Radiation Therapy Utilization for Primary Cutaneous T-Cell Lymphoma Is Lowest Among Patients Living in the Most Geographically Accessible Areas: An Australian Study.
International journal of radiation oncology, biology, physics
Int J Radiat Oncol Biol Phys
null
null
10.1016/j.ijrobp.2025.07.054
eng
2,025
7
13
2,025
7
13
[PURPOSE] Cutaneous T-cell lymphomas (CTCL) are rare with increasing incidence. Most patients have skin-confined mycosis fungoides: a typically indolent, highly morbid, incurable disease requiring multi-lined treatment. For these patients, radiation therapy (RT) is efficacious, well-tolerated, and cost-effective; total...
null
2.058
286
Cancer Research; Oncology; Radiation; Radiology, Nuclear Medicine and Imaging
Biochemistry, Genetics and Molecular Biology; Medicine; Physics and Astronomy
2,024
40,663,875
Retrospective study on treatment outcomes of two-stage bone grafting vs. amputation in distal phalangeal osteomyelitis.
Injury
Injury
56
8
10.1016/j.injury.2025.112597
eng
2,025
8
null
2,025
7
9
[BACKGROUND] This study aims to evaluate the outcomes of two-stage bone grafting versus amputation for the treatment of distal phalangeal osteomyelitis. [METHODS] We conducted a retrospective multicenter study of 102 patients with distal phalangeal osteomyelitis, of whom 53 underwent amputation and 49 underwent two-sta...
Amputation; Bone grafting; Distal phalangeal osteomyelitis; Induced membrane
0.762
151
Emergency Medicine; Surgery; Orthopedics and Sports Medicine
Medicine
2,024
40,663,720
A Modified Bi-Muscular Flap Technique for Breast Augmentation:Does Extra Muscle Support Enhance the Stability of Smooth Implants?
Plastic and reconstructive surgery
Plast Reconstr Surg
null
null
10.1097/PRS.0000000000012280
eng
2,025
7
1
2,025
7
1
[BACKGROUND] Following the concerns of breast implant-associated anaplastic large cell lymphoma, smooth implants are being increasingly used instead. However, the lack of sufficient lower pole support for smooth implants using the dual-plane method has given rise to complications including rippling, implant malposition...
null
1.222
220
Surgery
Medicine
2,024
40,663,396
Integrative mapping of pre-existing influenza immune landscapes predicts vaccine response.
The Journal of clinical investigation
J Clin Invest
null
null
10.1172/JCI189300
eng
2,025
7
15
2,025
7
15
[BACKGROUND] Predicting individual vaccine responses is a substantial public health challenge. We developed immunaut, an open-source, data-driven framework for systems vaccinologists to analyze and predict immunological outcomes across diverse vaccination settings, beyond traditional assessments. [METHODS] Using a comp...
Adaptive immunity; Clinical Research; Immunology; Influenza; Vaccines; Virology
4.721
558
Medicine
Medicine
2,024
40,663,197
Physician Moral Injury During the COVID-19 Pandemic.
Journal of general internal medicine
J Gen Intern Med
null
null
10.1007/s11606-025-09690-5
eng
2,025
7
15
2,025
7
15
[BACKGROUND] Moral injury is defined as lasting distress due to perpetrating, failing to prevent, or witnessing acts that transgress or deeply violate one's moral or ethical code. Previous research has demonstrated that during the COVID-19 pandemic, healthcare workers were at increased risk of moral injury. However, th...
COVID-19; Moral injury; Physicians; Qualitative research
1.992
224
Internal Medicine
Medicine
2,024
40,663,140
Branched-chain amino acids and risk of major depressive disorder: a Mendelian randomization and colocalization study.
Psychopharmacology
Psychopharmacology (Berl)
null
null
10.1007/s00213-025-06851-6
eng
2,025
7
15
2,025
7
15
[AIMS] Depression is associated with numerous metabolic pathway abnormalities, and several studies have suggested a link between depression and branched chain amino acids (BCAAs) metabolic disorders. However, the precise causality and direction remain inconclusive. Consequently, this study aims to ascertain the relatio...
Branched-chain amino acids; Genome-wide association study; Major depressive disorder; Mendelian randomization; Valine
1.157
218
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,024
40,663,087
Frailty Assessment and NK Cell Function in Multiple Myeloma: a Comprehensive Analysis.
Clinical laboratory
Clin Lab
71
7
10.7754/Clin.Lab.2024.241121
eng
2,025
7
1
null
null
null
[BACKGROUND] Frailty is a clinical syndrome characterized by decreased muscle strength and endurance, as well as deterioration of multiple system functions and metabolic status. Frailty is particularly common in patients with multiple myeloma (MM), which seriously affects their quality of life. [METHODS] From January t...
null
null
null
null
null
null
40,662,758
Management of bilioenteric anastomosis leakage after major liver resection.
BJS open
BJS Open
9
4
10.1093/bjsopen/zraf075
eng
2,025
7
1
null
null
null
[BACKGROUND] Post-hepatectomy bile leakage is a challenging issue that can lead to morbidities and mortality after liver resection. This leakage can occur either from a bilioenteric anastomosis (BEA) or from the transected surface of the liver. This study investigated the incidence, risk factors, and effective manageme...
bile duct anastomosis; hepatectomy; post-hepatectomy bile leakage; post-hepatectomy complications
1.241
39
Medicine; Surgery
Medicine
2,024
40,662,650
The use of the Odds Ratio Product (ORP) and self-reported data to detect comorbid insomnia and sleep apnea.
Sleep
Sleep
null
null
10.1093/sleep/zsaf198
eng
2,025
7
15
2,025
7
15
[STUDY OBJECTIVES] To evaluate the utility of the Odds Ratio Product (ORP) in differentiating comorbid insomnia and sleep apnea (COMISA) from obstructive sleep apnea (OSA) and chronic insomnia (CIN). [METHODS] We retrospectively analyzed 9750 patients in four groups: 1) 1152 controls; 2) 2395 with CIN; 3) 2297 with OSA...
chronic insomnia; comorbid insomnia and sleep apnea; obstructive sleep apnea; odds ratio product
1.796
248
Behavioral Neuroscience; Clinical Psychology; Neurology; Neuropsychology and Physiological Psychology; Physiology
Medicine; Neuroscience; Psychology
2,024
40,662,378
First-in-human study of HDM1002, a GLP-1 receptor agonist: Safety, tolerability, pharmacokinetics and pharmacodynamics of escalating single oral doses in healthy volunteers.
Diabetes, obesity & metabolism
Diabetes Obes Metab
null
null
10.1111/dom.16610
eng
2,025
7
15
2,025
7
15
[AIMS] To evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single oral doses of HDM1002 in healthy adult participants. [MATERIALS AND METHODS] This was a first-in-human, randomized, double-blind, placebo-controlled, 2-part study. Healthy participants aged 18 to 55 years with a body ...
pharmacokinetics; type 2 diabetes mellitus
null
null
null
null
null
40,662,221
Vagal Stimulation Rescues HFpEF by Altering Cardiac Resident Macrophage Function.
Circulation research
Circ Res
137
5
10.1161/CIRCRESAHA.125.326236
eng
2,025
8
15
2,025
7
15
[BACKGROUND] We previously showed in a rat model of heart failure with preserved ejection fraction (HFpEF) that transcutaneous vagus nerve stimulation (tVNS) reduced cardiac fibrosis and inflammation. However, macrophage-mediated mechanisms through which tVNS rescues cardiac function remain poorly understood. [METHODS]...
acetylcholine; heart failure; inflammation; macrophages; vagus nerve stimulation
4.897
402
Cardiology and Cardiovascular Medicine; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,662,151
Investigation of the relationship between fluconazole susceptibility, proteinase activity and ERG11-SAP2 Expression in Candida albicans strains isolated from clinical samples.
Current medical mycology
Curr Med Mycol
10
null
10.22034/cmm.2024.345311.1585
eng
2,024
null
null
2,024
12
31
[BACKGROUND AND PURPOSE] Candida albicans is currently recognised as an opportunistic pathogen that can cause many invasive infections. Resistance mechanisms and fungal virulence factors play an important role in the effectiveness of treatment. The aim of this study was to investigate the relationship between fluconazo...
Fluconazole; Proteinase; Tolerance; Candida albicans
null
null
null
null
null
40,661,940
Longitudinal immune profiling following autologous hematopoietic stem cell transplantation in multiple sclerosis: insights into immune reconstitution and disease modulation.
Frontiers in immunology
Front Immunol
16
null
10.3389/fimmu.2025.1601223
eng
2,025
null
null
2,025
6
30
[INTRODUCTION] Autologous hematopoietic stem cell transplantation (AHSCT) is an effective treatment for relapsing remitting multiple sclerosis, yet the mechanisms underlying immune reset and sustained remission remain incompletely understood. This study provides a longitudinal immune profiling of patients undergoing AH...
flow cytometry; immune reconstitution; mass cytometry; multiple sclerosis (MS); neuroimmunology
1.941
259
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
40,661,929
Social support and recovery in acute respiratory distress syndrome survivors: a prospective cohort study.
ERJ open research
ERJ Open Res
11
4
10.1183/23120541.01113-2024
eng
2,025
7
null
2,025
7
14
[BACKGROUND] Social support (SS) may contribute to the long-term recovery of critical illness survivors. This study focuses on survivors of acute respiratory distress syndrome (ARDS) to investigate the causal relationship between SS and health-related quality of life (HRQoL) and healthcare utilisation in critically ill...
null
1.367
52
Pulmonary and Respiratory Medicine
Medicine
2,024
40,661,790
Evaluating the efficacy of curcumin plus serratiopeptidase formulation in inflammatory acne: a quasi-experimental study.
Drugs in context
Drugs Context
14
null
10.7573/dic.2025-4-2
eng
2,025
null
null
2,025
7
9
[BACKGROUND] Acne vulgaris is one of the most common dermatological illnesses affecting people worldwide. In Pakistan, approximately 9.4% of the population and between 5% and 16% of young adults are affected by acne vulgaris. Conventional therapies (topical benzoyl peroxide, retinoids, antibiotics and oral isotretinoin...
acne vulgaris; anti-inflammatory therapy; curcumin; quasi experimental; serratiopeptidase
0.775
40
Medicine; Pharmacology; Molecular Medicine
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,661,746
Development and validation of a nomogram for predicting diabetic foot ulcer risk in patients with type 2 diabetes mellitus.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
16
null
10.3389/fendo.2025.1555163
eng
2,025
null
null
2,025
6
30
[OBJECTIVE] To identify the risk factors of diabetic foot ulcer (DFU) in patients with type 2 diabetes mellitus (T2DM) and to develop and validate a nomogram prediction model for DFU occurrence in primary care setting. [METHODS] We conducted a single-center retrospective study enrolling 547 T2DM patients hospitalized a...
diabetic foot ulcer; nomogram; prediction; risk factors; type 2 diabetes mellitus
1.472
138
Endocrinology, Diabetes and Metabolism
Medicine
2,024
40,661,527
Composition of Carotid Plaques Differs Between Chinese and United States Patients: A Histology Study.
bioRxiv : the preprint server for biology
bioRxiv
null
null
10.1101/2025.06.10.658993
eng
2,025
6
13
2,025
6
13
[BACKGROUND] The clinical manifestations of cerebrovascular disease are known to differ between the Chinese and United States (U.S.) populations as do the plaque features on imaging. [OBJECTIVES] The aim of this study was to investigate and compare the histological features of excised carotid plaques from Chinese and U...
Atherosclerotic plaques; Carotid artery; Carotid endarterectomy; Histology
null
null
null
null
null
40,661,507
Mechanosensitive Endothelial METTL7A Regulates Internal m [7] G mRNA Methylation and Protects Against Atherosclerosis.
bioRxiv : the preprint server for biology
bioRxiv
null
null
10.1101/2025.05.22.655328
eng
2,025
5
26
2,025
5
26
[BACKGROUND] Internal N [7] -methylguanosine (m [7] G) is a recently identified chemical modification of mammalian mRNA and a component of the epitranscriptome. While the epitranscriptome plays a key role in regulating RNA metabolism and cellular function, the specific contribution of internal m [7] G to cardiovascular...
null
null
null
null
null
null
40,661,314
Patient-derived gastric cancer organoids model heterogeneity and stroma-mediated chemoresistance in poorly cohesive carcinoma.
Frontiers in molecular biosciences
Front Mol Biosci
12
null
10.3389/fmolb.2025.1631168
eng
2,025
null
null
2,025
6
30
[OBJECTIVE] Gastric cancer (GC) remains a leading cause of cancer-related mortality, with poorly cohesive carcinoma (PCC) exhibiting rising incidence and poor therapeutic responses. In this study, we constructed a panel of patient-derived organoids of GC and used them to understand histological accuracy and sensitivity...
drug sensitivity; gastric cancer (GC); patient-derived organoids; poorly cohesive carcinoma (PCC); tumor microenvironment
1.243
85
Biochemistry; Biochemistry, Genetics and Molecular Biology; Molecular Biology
Biochemistry, Genetics and Molecular Biology
2,024
40,661,250
Comparing Park Table - Augmented and Standard Surgical Doses in Acute Acquired Comitant Esotropia: A Retrospective Analysis.
Clinical ophthalmology (Auckland, N.Z.)
Clin Ophthalmol
19
null
10.2147/OPTH.S530750
eng
2,025
null
null
2,025
7
10
[PURPOSE] Acquired comitant esotropia (ACE) is a rare condition characterized by the sudden onset of inward eye deviation. In non-recovered cases, surgery was performed. The standard surgical dose typically leads to undercorrection, and multimodal approaches were used to enhance outcomes. The current study aimed to exp...
acquired comitant esotropia; clinical course; etiology; incidence; surgical outcomes; tertiary hospital
0.936
84
Ophthalmology
Medicine
2,024
40,660,641
Amphiregulin activation upon ZEB1 loss promotes pro-inflammatory activation and osteoclastic differentiation of macrophages in rheumatoid arthritis.
Cytokine
Cytokine
194
null
10.1016/j.cyto.2025.156993
eng
2,025
7
13
2,025
7
13
[BACKGROUND] Rheumatoid arthritis (RA) is a multifactorial autoimmune disease primarily affecting the joints. This study, grounded on bioinformatics insights, investigates the biological effects of zinc finger E-box binding homeobox 1 (ZEB1) in the context of RA and delves into the functional mechanism. [METHODS] A mur...
AREG; Inflammation; Macrophages; Osteoclastogenesis; Rheumatoid arthritis; ZEB1
1.108
142
Biochemistry; Hematology; Immunology; Immunology and Allergy; Molecular Biology
Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine
2,024
40,660,315
Application value of indocyanine green lymphography in the management of stage I/IIA microcystic lymphatic malformation of the tongue.
Head & face medicine
Head Face Med
21
1
10.1186/s13005-025-00529-2
eng
2,025
7
14
2,025
7
14
[BACKGROUND] This study aims to investigate whether indocyanine green lymphography (ICGL) facilitates the effectiveness and accuracy of current management of lingual microcystic lymphatic malformation (mLM). [METHODS] This retrospective included patients under 18 years old with mLM of the tongue staged I or IIA, who un...
Children; Indocyanine green lymphography; Microcystic lymphatic malformation; Tongue
null
null
null
null
null
40,660,276
Efficacy of long-term oral nutritional supplementation with dietary counseling on growth, body composition and bone mineralization in children with or at risk for undernutrition: a randomized controlled trial.
Nutrition journal
Nutr J
24
1
10.1186/s12937-025-01133-5
eng
2,025
7
14
2,025
7
14
[BACKGROUND] Impaired growth, accompanied by low lean mass and poor bone mineralization in undernourished children, is linked to adverse short- and long-term health outcomes. Oral nutritional supplements (ONS) promote catch-up growth, but their efficacy in improving lean mass and bone mineralization remains uninvestiga...
Catch-up growth; Fat mass; Lean mass; Stunting; Underweight; Wasting
1.221
119
Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
40,660,102
Predicting the molecular subtypes of 2021 WHO grade 4 glioma by a multiparametric MRI-based machine learning model.
BMC cancer
BMC Cancer
25
1
10.1186/s12885-025-14529-7
eng
2,025
7
14
2,025
7
14
[BACKGROUND] Accurately distinguishing the different molecular subtypes of 2021 World Health Organization (WHO) grade 4 Central Nervous System (CNS) gliomas is highly relevant for prognostic stratification and personalized treatment. [OBJECTIVES] To develop and validate a machine learning (ML) model using multiparametr...
Astrocytoma; Glioblastoma; Machine learning; Magnetic resonance imaging; Molecular subtype
1.178
171
Cancer Research; Genetics; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,659,927
Soluble Transferrin Receptor-1 in Pulmonary Hypertension Associated with COPD.
Lung
Lung
203
1
10.1007/s00408-025-00833-3
eng
2,025
7
14
2,025
7
14
[PURPOSE] The pulmonary vascular involvement of COPD ranges from severe airway obstruction without pulmonary hypertension (PH) to mild airway obstruction with severe PH. Iron-dependent molecular regulators like hypoxia-inducible factor-2 (HIF-2) may contribute to these phenotypic variations. We explored the role of sol...
Biomarker; COPD; Iron; Pulmonary hypertension; Soluble transferrin receptor-1
1.007
74
Pulmonary and Respiratory Medicine
Medicine
2,024
40,659,518
Extralobar pulmonary sequestration as an intraabdominal tumour.
Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti
Rozhl Chir
104
4
10.48095/ccrvch2025155
eng
2,025
null
null
null
null
null
[INTRODUCTION] Pulmonary sequestration is a rare congenital anomaly of the lower respiratory tract, usually diagnosed in childhood. It involves lung parenchyma that has abnormal or absent communication with the tracheobronchial tree. The blood supply is not connected to the pulmonary circulation but comes from the syst...
congenital lung malformations; extralobar lung sequestration; intraabdominal tumour
null
null
null
null
null
40,659,437
Technostress among digital generations nurse educators in South-Central Mindanao Philippines.
Journal of professional nursing : official journal of the American Association of Colleges of Nursing
J Prof Nurs
59
null
10.1016/j.profnurs.2025.04.015
eng
2,025
null
null
2,025
5
1
[BACKGROUND] Technostress is a modern adaptation issue resulting from the difficulty of adapting to technological use. Integrating technology in teaching and learning during the sudden shift of teaching modalities exposes nursing educators to technostress. [AIM] To determine and compare the levels of technostress exper...
Digital immigrant; Digital native; Nurse-educator; Philippines; Technostress
1.022
67
Medicine; Nursing
Medicine; Nursing
2,024
40,659,079
Influence of extraoral scan body design on accuracy of scans recorded using four intraoral and one desktop scanner, with and without AI features: An In Vitro Study.
Journal of dentistry
J Dent
161
null
10.1016/j.jdent.2025.105970
eng
2,025
7
12
2,025
7
12
[OBJECTIVES] The aim of this in vitro study was to evaluate the impact of extraoral scan body (ESB) design on the scanning accuracy of a digitized facebow fork along with the attached ESB, using four intraoral scanners (IOS) and one extraoral desktop scanner (EOS), with and without the assistance of the available integ...
Artificial intelligence; Extraoral scanbody; Face scan; Intraoral scanner; Scanning accuracy; Virtual mounting; Virtual patient
1.53
146
Dentistry
Dentistry
2,024
40,658,749
Quality of life in patients with heart failure and implantable cardioverter defibrillator. Results from 9 274 patients in 42 outpatient heart failure clinics in the National Norwegian Heart Failure Registry.
European heart journal. Quality of care clinical outcomes
Eur Heart J Qual Care Clin Outcomes
null
null
10.1093/ehjqcco/qcaf062
eng
2,025
7
14
2,025
7
14
[AIMS] Patients with heart failure (HF) have increased risk of sudden cardiac death, and treatment with an implantable cardioverter defibrillator (ICD) has become standard treatment for selected patient groups. HF is associated with impaired quality of life (QoL), but studies on QoL in patients with HF and ICD attendin...
Heart failure; Implantable cardioverter defibrillator; Outpatient clinic; quality of life
null
null
null
null
null
40,658,500
A Systematic Review Supporting the Endocrine Society Clinical Practice Guideline on Management of Primary Aldosteronism.
The Journal of clinical endocrinology and metabolism
J Clin Endocrinol Metab
110
9
10.1210/clinem/dgaf290
eng
2,025
8
7
null
null
null
[CONTEXT] Primary aldosteronism (PA) is a leading endocrine cause of secondary hypertension. [OBJECTIVE] To support the development of the Endocrine Society Clinical Practice Guideline on managing PA. [DATA SOURCE] MEDLINE, Embase, Scopus, and others were searched on October 4, 2024. [STUDY SELECTION] Studies were sele...
Endocrine Society; guidelines; meta-analysis; primary aldosteronism; systematic review
2.183
400
Biochemistry; Biochemistry; Clinical Biochemistry; Endocrinology; Endocrinology, Diabetes and Metabolism; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,658,184
Nodal metastasis in surgically treated sinonasal squamous cell carcinoma.
Discover oncology
Discov Oncol
16
1
10.1007/s12672-025-02899-0
eng
2,025
7
14
2,025
7
14
[OBJECTIVES] Tumor factors such as subsite and stage impact the risk of lymph node metastasis (LNM) and overall risk in sinonasal squamous cell carcinoma (SNSCC). We sought to identify the rates of patients presenting with or without clinical LNM for different tumor subsites and stages of surgically-treated SNSCC, dete...
Head and neck; Lymph node dissection; Nodal metastasis; Squamous cell carcinoma
0.88
47
Endocrine and Autonomic Systems; Endocrinology; Endocrinology, Diabetes and Metabolism; Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
40,658,078
Prevalent vertebral fractures and the diabetic bone paradox in women who sustain a hip fracture: a cross-sectional study.
European journal of physical and rehabilitation medicine
Eur J Phys Rehabil Med
null
null
10.23736/S1973-9087.25.08894-X
eng
2,025
7
14
2,025
7
14
[BACKGROUND] Patients with type 2 diabetes mellitus (T2DM) have enhanced fracture risk despite high bone mineral density (BMD), a phenomenon known as the diabetic bone paradox. Consistently with the paradox, hip fractures occur at higher BMD in women with T2DM than in controls. However, no studies have addressed BMD in...
null
0.975
79
Physical Therapy, Sports Therapy and Rehabilitation; Rehabilitation
Health Professions; Medicine
2,024
40,657,971
Longitudinal Study of Changes in Retinal Curvature and its Relationship With Myopia Shift in Chinese Children.
Investigative ophthalmology visual science
Invest Ophthalmol Vis Sci
66
9
10.1167/iovs.66.9.37
eng
2,025
7
1
null
null
null
[PURPOSE] The purpose of this study was to investigate longitudinal changes in retinal curvature (RC) among Chinese children and its relationship with myopia progression. [METHODS] This 12-month longitudinal study included children aged 6 to 16 years, divided into groups based on changes in spherical equivalent refract...
null
null
null
null
null
null
40,657,968
Toward the Characterization of the Human Core Ocular Surface Microbiome.
Investigative ophthalmology visual science
Invest Ophthalmol Vis Sci
66
9
10.1167/iovs.66.9.40
eng
2,025
7
1
null
null
null
[PURPOSE] The field of ocular surface microbiome (OSM) research suggests its involvement in ocular surface (OS) health and disease. However, existing OSM data are heterogeneous. This study aims to provide a whole-metagenome shotgun sequencing-based description of the healthy core ocular surface microbiome (COSM), encom...
null
null
null
null
null
null
40,657,591
Interventions that strengthen the care workforce: a realist synthesis review.
Health affairs scholar
Health Aff Sch
3
7
10.1093/haschl/qxaf128
eng
2,025
7
null
2,025
6
28
[INTRODUCTION] Health systems depend on care workers to provide "hands-on" direct care with eating, dressing, and other needs, as well as indirect care with household tasks, meals, and transport. Care workers are in high demand to support growing populations who need help in daily life, yet they often fall outside of h...
care workers; health human resources; workforce planning
null
null
null
null
null
40,657,289
Age-sex differences in Alzheimer's and related dementias burden and risk factors in east and Southeast Asia: results from the 2021 GBD study.
Frontiers in aging neuroscience
Front Aging Neurosci
17
null
10.3389/fnagi.2025.1562148
eng
2,025
null
null
2,025
6
27
[BACKGROUND] Alzheimer's disease and related dementias (ADRD) significant global public health challenges, leading to severe disability in patients and placing a heavy burden on caregivers. However, epidemiological studies focusing on ADRD in specific regions remain limited. This study aims to comprehensively analyze a...
East and Southeast Asia; GBD (2021) database; age-sex differences; burden of disease; risk factor
1.479
135
Cognitive Neuroscience; Aging
Biochemistry, Genetics and Molecular Biology; Neuroscience
2,024
40,656,786
Novel risk prediction model for major adverse cardiovascular events in minimally invasive mitral valve surgery: a retrospective study.
Cardiovascular diagnosis and therapy
Cardiovasc Diagn Ther
15
3
10.21037/cdt-2025-25
eng
2,025
6
30
2,025
6
26
[BACKGROUND] Minimally invasive mitral valve surgery (MIMVS) has become the standard procedure for treating mitral valve pathologies. However, the existing cardiac risk model fails to consider the distinctive perfusion and ventilation techniques of MIMVS, leading to inaccurate prediction of perioperative risks. This st...
Minimally invasive mitral valve surgery (MIMVS); major adverse cardiovascular events (MACEs); mitral valve surgery; risk prediction model
0.707
47
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,656,666
Prevalence, antimicrobial susceptibility patterns, and associated risk factors of Enterococci species in healthcare and community settings in Ethiopia: a systematic review and meta-analysis.
Therapeutic advances in infectious disease
Ther Adv Infect Dis
12
null
10.1177/20499361251354905
eng
2,025
null
null
2,025
7
8
[BACKGROUND] Enterococci are significant contributors to healthcare-associated infections in Ethiopia. [OBJECTIVES] This systematic review and meta-analysis synthesize data on the prevalence, antimicrobial susceptibility patterns, and associated risk factors for Enterococcus infections in Ethiopia. [DESIGN] Systematic ...
AMR; Enterococci; antimicrobial resistance; associated risk factors; prevalence
1.197
34
Infectious Diseases; Pharmacology
Medicine
2,024
40,656,494
Endoscopic endonasal drainage of a foreign body-associated brain abscess.
Surgical neurology international
Surg Neurol Int
16
null
10.25259/SNI_90_2025
eng
2,025
null
null
2,025
6
6
[BACKGROUND] Although brain abscesses (BA) are uncommon, they represent a significant clinical challenge due to their potential for high morbidity and mortality. When combined with the presence of foreign bodies (FB), such as those resulting from penetrating craniofacial trauma, the management of BA becomes even more c...
Brain abscess; Endonasal endoscopic; Foreign body; Sublabial transmaxillary
0.351
48
Neurology; Surgery
Medicine
2,024
40,655,886
Arthroscopic Debridement and Proximal Fibular Osteotomy in the management of knee Osteoarthritis: A Descriptive Longtudinal Study.
JNMA; journal of the Nepal Medical Association
JNMA J Nepal Med Assoc
62
278
10.31729/jnma.8778
eng
2,024
10
null
2,024
10
31
[INTRODUCTION] Knee osteoarthritis commonly occurs in the medial compartment. Arthroscopic debridement eases pain by irrigating debris and inflammatory cytokines. Proximal fibular osteotomy shifts the loading force more laterally from the medial compartment, eliminating pain and delaying degenerative progression. This ...
arthroscopic debridement; knee osteoarthritis; proximal fibular osteotomy
null
null
null
null
null
40,655,808
Exploration of the Role of Music Therapy in Reducing Dental Anxiety.
Journal of pharmacy bioallied sciences
J Pharm Bioallied Sci
17
Suppl 2
10.4103/jpbs.jpbs_85_25
eng
2,025
6
null
2,025
6
18
[BACKGROUND] A large percentage of patients suffer from dental anxiety, which often results in poor oral health and avoidance of dental treatment. One noninvasive, reasonably priced strategy that may help with anxiety management is music therapy. [MATERIALS AND METHODS] For this randomized controlled experiment, 60 ind...
Anxiety reduction; Modified Dental Anxiety Scale (MDAS); dental anxiety; music therapy; patient comfort
null
null
null
null
null
40,655,674
Comparative Evaluation of Demineralized Freeze-Dried Bone Allograft Combined with 0.75% Boric Acid Gel versus Demineralized Freeze-Dried Bone Allograft Alone in the Management of Subclass-B Furcation Defects.
Journal of pharmacy bioallied sciences
J Pharm Bioallied Sci
17
Suppl 2
10.4103/jpbs.jpbs_1824_24
eng
2,025
6
null
2,025
6
18
[AIM] This study aims to compare the efficacy of demineralized freeze-dried bone allograft (DFDBA) combined with 0.75% boric acid gel versus DFDBA alone in managing subclass-B furcation defects. [METHODS] A split-mouth clinical trial design was adopted, involving 20 sites with bilateral Grade B furcation defects in fir...
Boric acid gel; chronic periodontitis; demineralized freeze-dried bone allograft
null
null
null
null
null
40,655,586
Comparative Evaluation of Antimicrobial Photodynamic Therapy Using Methylene Blue (660 nm Diode Laser) and Indocyanine Green (810 nm Diode Laser) in the Management of Chronic Periodontitis: A Clinical and Microbiological Study.
Journal of pharmacy bioallied sciences
J Pharm Bioallied Sci
17
Suppl 2
10.4103/jpbs.jpbs_1823_24
eng
2,025
6
null
2,025
6
18
[AIM] The purpose of this study was to compare the microbiological and clinical effects of antimicrobial photodynamic therapy (aPDT) in treating chronic periodontitis by using indocyanine green (ICG) with an 810 nm diode laser and methylene blue (MB) with a 660 nm diode laser as adjuncts to scaling and root planing (SR...
Chronic periodontitis; indocyanine green; methylene blue; periodontopathogens; photodynamic therapy; polymerase chain reaction
null
null
null
null
null
40,655,539
Possibility of screening for mild cognitive impairment via an eye tracking-based cognitive scale.
Frontiers in aging
Front Aging
6
null
10.3389/fragi.2025.1532550
eng
2,025
null
null
2,025
6
27
[INTRODUCTION] The Montreal Cognitive Assessment (MoCA) is widely used as a screening test for mild cognitive impairment (MCI). However, the MoCA takes approximately 15 min to administer and evaluate by skilled examiners, such as medical professionals. This study assessed whether an eye tracking-based cognitive scale u...
eye tracking-based cognitive scale; mild cognitive impairment; screening; virtual reality
1.455
20
Genetics; Molecular Biology; Physiology; Aging
Biochemistry, Genetics and Molecular Biology
2,024
40,655,494
Mediating Role of Physical Activity in the Relationship between Personality Traits and Body Mass Index (BMI) among the Participants of the Employees' Health Cohort Study of Iran (EHCSIR): A Generalized Structural Equation Modeling.
Iranian journal of public health
Iran J Public Health
54
6
10.18502/ijph.v54i6.18905
eng
2,025
6
null
null
null
null
[BACKGROUND] Considering the high importance of the problem of obesity and its related factors, we aimed to investigate the mediating role of physical activity in the relationship between personality traits and body mass index (BMI) in the participants of the employees' health cohort study of Iran (EHCSIR) using genera...
Body mass index; Personality; Physical activity; Statistical models; Structural equation modeling
0.489
60
Public Health, Environmental and Occupational Health
Medicine
2,024
40,655,402
Real-World effectiveness of eculizumab in atypical hemolytic uremic syndrome: a retrospective study from Western China.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
16
null
10.3389/fendo.2025.1568082
eng
2,025
null
null
2,025
6
27
[OBJECTIVE] To evaluate the real-world efficacy and safety of eculizumab in atypical hemolytic uremic syndrome (aHUS) within a Western Chinese cohort, with emphasis on treatment initiation timing and renal outcomes. [METHODS] We conducted a retrospective analysis of 17 aHUS patients treated at Sichuan Provincial People...
China; atypical hemolytic uremic syndrome; eculizumab; efficiency; retrospective study; safety
1.472
138
Endocrinology, Diabetes and Metabolism
Medicine
2,024
40,655,401
Hashimoto's thyroiditis and nanophthalmos in Gabriele-de Vries syndrome: a case report.
Frontiers in endocrinology
Front Endocrinol (Lausanne)
16
null
10.3389/fendo.2025.1583190
eng
2,025
null
null
2,025
6
27
[BACKGROUND] Gabriele-de Vries syndrome (GADEVS, OMIM 617557) is a rare autosomal dominant disorder caused by pathogenic variants in the YY1 gene. This report describes a case of GADEVS with concurrent Hashimoto's thyroiditis (HT) and nanophthalmos, a previously unreported association. [CASE PRESENTATION] We present a ...
Gabriele-de Vries syndrome; YY1; adolescent; case report; nanophthalmos
1.472
138
Endocrinology, Diabetes and Metabolism
Medicine
2,024
40,655,257
Reduced quadriceps deficit following dry arthroscopy compared to standard fluid arthroscopy at the time of MPFL reconstruction.
Journal of experimental orthopaedics
J Exp Orthop
12
3
10.1002/jeo2.70367
eng
2,025
7
null
2,025
7
13
[PURPOSE] Recurrent patellar dislocations (RPDs) are prevalent, particularly among adolescents. The 'Menu à la carte' technique facilitates personalized management of each patient through reconstruction of the medial patellofemoral ligament (MPFL) while simultaneously addressing other anatomical factors that may contri...
MPFL; RPD; arthrogenic muscle inhibition; dry arthroscopy; knee; quadriceps deficit
0.937
39
Orthopedics and Sports Medicine
Medicine
2,024
40,655,215
Spatial disparities of antenatal care utilization among pregnant women in sub-Saharan Africa-Bayesian geo-additive modelling approach.
Frontiers in public health
Front Public Health
13
null
10.3389/fpubh.2025.1517724
eng
2,025
null
null
2,025
6
27
[BACKGROUND] Antenatal care (ANC) is critical for ensuring healthy pregnancies and positive birth outcomes. Despite its importance, significant disparities in ANC access and utilization exist across sub-Saharan Africa (SSA), influenced by various socioeconomic, geographical, and systemic factors. This study aimed to an...
INLA; antenatal care contacts; geo-additive; spatial disparities; sub-Saharan Africa
1.027
119
Public Health, Environmental and Occupational Health
Medicine
2,024
40,655,052
Multidrug Resistance Gram-negative Bacteria in Intensive Care Unit of Tertiary Care Hospital: A Descriptive Cross-sectional Study.
JNMA; journal of the Nepal Medical Association
JNMA J Nepal Med Assoc
62
277
10.31729/jnma.8747
eng
2,024
9
null
2,024
9
30
[INTRODUCTION] Antimicrobial resistance is global health problem, amongst major causes for mortality. It is one of the hinderance for achievement of Sustainable Goal 3 (Good health and well-being) of World Health Organization. Multidrug resistant gram negative bacteria are major threat to humanity especially patients a...
acinetobacter; gram negative bacteria; intensive care unit; multi drug resistance
null
null
null
null
null
40,654,614
High-Resolution Spatial Proteomics Characterises Colorectal Cancer Consensus Molecular Subtypes.
bioRxiv : the preprint server for biology
bioRxiv
null
null
10.1101/2025.05.07.652478
eng
2,025
7
8
2,025
7
8
[BACKGROUND] Identification of the consensus molecular subtypes (CMS) opened significant potential for understanding the tumor biology and intertumoral heterogeneity of colorectal cancer (CRC). However, molecular subtyping in CRC traditionally relies on bulk transcriptomics, therefore, lacks spatial and single-cell lev...
null
null
null
null
null
null
40,654,130
Chronic Glymphatic Dysfunction Modulates Domain-Specific Cognitive Recovery After Stroke: A DTI-ALPS Lesion Stratification Study.
CNS neuroscience therapeutics
CNS Neurosci Ther
31
7
10.1111/cns.70512
eng
2,025
7
null
null
null
null
[BACKGROUND AND AIMS] Glymphatic dysfunction may exacerbate post-stroke cognitive impairment (PSCI) via impaired metabolic waste clearance. However, longitudinal dynamics of glymphatic function during the chronic stroke phase (3-12 months) and links to cognitive recovery remain unclear. This study aimed to characterize...
chronic stroke; cognitive recovery; glymphatic system
null
null
null
null
null
40,653,572
Adherence to 24-h Movement Guidelines in children: a systematic review and meta-analysis.
European journal of pediatrics
Eur J Pediatr
184
8
10.1007/s00431-025-06308-0
eng
2,025
7
14
2,025
7
14
[UNLABELLED] Adherence to the 24-h Movement Guidelines (physical activity [PA], screen time [ST], and sleep duration) has been associated with positive health outcomes. However, meta-analyses on overall adherence to these guidelines among children remain limited. This study aimed to report children's adherence to the 2...
Accelerometer; Moderate to vigorous physical activity; Questionnaire; Screen time; Sleep duration
0.934
115
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,653,301
Five Year Outcomes of the Fabulous Stent System in the Management of Complicated Type B Aortic Dissection: A Prospective Multicentre Study.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Eur J Vasc Endovasc Surg
null
null
10.1016/j.ejvs.2025.07.020
eng
2,025
7
11
2,025
7
11
[OBJECTIVE] This study aimed to assess the 5 year follow up results from a prospective, single arm, multicentre study evaluating the efficacy of the Fabulous stent system (DiNovA Meditech, Hangzhou, China) in the treatment of complicated Stanford type B aortic dissection (cTBAD). [METHODS] From December 2017 to October...
Aortic remodelling; Bare stent; Fabulous; PETTICOAT; Type B aortic dissection
1.512
144
Cardiology and Cardiovascular Medicine; Surgery
Medicine
2,024
40,653,257
The Effect of Metagenomic Sequencing on Patient Clinical Outcomes for Intraocular Infections: A Multicenter Randomized Controlled Trial.
American journal of ophthalmology
Am J Ophthalmol
279
null
10.1016/j.ajo.2025.07.003
eng
2,025
7
11
2,025
7
11
[OBJECTIVE] To determine whether the addition of an unbiased test, metagenomic sequencing of intraocular fluid, compared to standard-of-care diagnostics alone, leads to better patient outcomes in presumed infectious intraocular inflammatory eye diseases. [DESIGN] A randomized controlled trial was conducted from May 202...
null
2.103
221
Ophthalmology
Medicine
2,024
40,652,960
How Does Thrombocytopenia Affect Outcomes in Head and Neck Cancer Surgery With Free Flap Reconstruction?
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
J Oral Maxillofac Surg
null
null
10.1016/j.joms.2025.06.225
eng
2,025
6
26
2,025
6
26
[BACKGROUND] Thrombocytopenia is associated with a variety of medical comorbidities seen in patients with head and neck cancer. However, it remains unclear if and how thrombocytopenia affects surgical outcomes. [PURPOSE] The purpose of this study was to measure the association between thrombocytopenia and 30-day advers...
null
0.767
147
Oral Surgery; Otorhinolaryngology; Surgery
Dentistry; Medicine
2,024
40,652,886
Admission to specialised neurocritical units and association with clinical outcomes.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
J Clin Neurosci
139
null
10.1016/j.jocn.2025.111471
eng
2,025
7
12
2,025
7
12
[BACKGROUND] Globally, managing critically ill adults with acute brain injuries (ABIs) in specialised neurocritical units (NCCUs) is associated with improved survival, but this has not been assessed in Australia. This study aims to determine in adults with an ABI if admission to a general intensive care unit (ICU) or a...
Brain injuries; Cerebral haemorrhage; Critical care; Intensive care units; Ischaemic stroke; Subarachnoid haemorrhage
0.654
104
Medicine; Surgery; Neurology; Neurology; Physiology
Medicine; Neuroscience
2,024
40,652,781
Plasma kynurenine pathway metabolites in association with diabetes: A cross-sectional study.
Clinical nutrition (Edinburgh, Scotland)
Clin Nutr
51
null
10.1016/j.clnu.2025.07.003
eng
2,025
8
null
2,025
7
7
[BACKGROUND] Abnormalities of the kynurenine pathway of tryptophan catabolism have been linked with an increased risk of cardiovascular disease. However, the association between kynurenine pathway metabolism and diabetes remains unclear. [METHODS] We conducted a secondary analysis of the baseline data of 796 adults fro...
Diabetes; Kynurenine pathway; Plasma metabolites; Tryptophan
2.212
183
Critical Care and Intensive Care Medicine; Nutrition and Dietetics
Medicine; Nursing
2,024
40,652,675
Autonomic arousal and heart rate variability in functional somatic disorder - a cross-sectional population-based study.
Journal of psychosomatic research
J Psychosom Res
196
null
10.1016/j.jpsychores.2025.112193
eng
2,025
7
6
2,025
7
6
[OBJECTIVE] The bodily distress syndrome (BDS) checklist has proven to be useful diagnostic aid and as screening tool for functional somatic disorder (FSD). It has been hypotheses that the symptoms clusters of the checklist represent autonomic activity. This study aims to investigate associations between autonomic acti...
BSD checklist; Chronic stress, general population; Epidemiology; Functional somatic disorders; Heart rate variability
1.308
182
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
40,652,613
The relationship between care dependency and self-efficacy in older adult patients with chronic obstructive pulmonary disease.
Heart lung : the journal of critical care
Heart Lung
74
null
10.1016/j.hrtlng.2025.07.004
eng
2,025
7
12
2,025
7
12
[BACKGROUND] Chronic obstructive pulmonary disease is a chronic, progressive and irreversible disease and is an important health problem with significant effects on the life status of older adult patients. However, the effect of care dependency on self-efficacy in older adult patients with chronic obstructive pulmonary...
Care dependency; Chronic obstructive pulmonary disease; Geriatric; Nursing; Self-efficacy
null
null
null
null
null
40,652,207
Knowledge, attitudes, and practices of Chinese college students towards novel psychoactive substances.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-23644-w
eng
2,025
7
12
2,025
7
12
[BACKGROUND] This study aimed to investigate the knowledge, attitudes, and practices (KAP) among Chinese college students regarding novel psychoactive substances (NPS), where practices specifically refer to behaviors related to NPS access and usage patterns. [METHODS] An online questionnaire was used to collect demogra...
Attitudes; Designer drugs; Health; Knowledge; Practice; Universities
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,652,204
Parents' experience in pediatric Tuina treatment program for congenital muscular torticollis in infants and children: qualitative findings from individual interviews.
BMC complementary medicine and therapies
BMC Complement Med Ther
25
1
10.1186/s12906-025-05000-y
eng
2,025
7
12
2,025
7
12
[BACKGROUND] Pediatric tuina treatment program is an intervention of traditional Chinese medicine that involves specific manual techniques applied to the bodies of infants and children to promote health and treat conditions such as congenital muscular torticollis (CMT). This study was conducted to understand facilitato...
Chinese medicine; Congenital muscular torticollis; Family care; Massage; Qualitative research
0.741
123
Complementary and Alternative Medicine
Medicine
2,024