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40,652,138
Efficacy of Dupilumab in the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP): a multicentric real-life study.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Eur Arch Otorhinolaryngol
null
null
10.1007/s00405-025-09540-4
eng
2,025
7
12
2,025
7
12
[PURPOSE] Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with morbidity and impairment in quality of life. Lately, new biological drugs have been developed and approved for its treatment. Dupilumab was the first to be approved but long-term real-world results are still limited. [METHODS] This is a real...
Biological drug; CRSwNP; Chronic rhinosinusitis; Dupilumab; Nasal polyposis; Olfaction
0.787
94
Otorhinolaryngology; Medicine
Medicine
2,024
40,651,525
Impact of Preoperative LDL Level on Lower Extremity Revascularization Outcomes.
Annals of vascular surgery
Ann Vasc Surg
122
null
10.1016/j.avsg.2025.07.016
eng
2,025
7
10
2,025
7
10
[BACKGROUND] Recent guidelines recommend achieving low-density lipoprotein (LDL) 70 mg/dL in patients with peripheral arterial disease (PAD). This study assesses the trends in LDL testing and its impact on lower extremity revascularization (LER) outcomes in a tertiary center. [METHODS] A retrospective chart review of ...
null
0.707
87
Cardiology and Cardiovascular Medicine; Medicine; Surgery
Medicine
2,024
40,651,456
Comparison of short- and mid-term outcomes of robotic versus laparoscopic gastrectomy in high-risk patients with gastric cancer: a nationwide, multicentre cohort study.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Eur J Surg Oncol
51
10
10.1016/j.ejso.2025.110294
eng
2,025
7
3
2,025
7
3
[BACKGROUND] To compare short-term and mid-term outcomes of robotic gastrectomy (RG) versus laparoscopic gastrectomy (LG) in high-risk gastric cancer (GC) patients. [METHODS] Patients with ≥1 of the following criteria were defined as high-risk: age ≥80 years; BMI ≥30 kg/m[2]; ASA grade ≥ III; and clinical T stage (cT4)...
Gastric cancer; High-risk patients; Laparoscopic gastrectomy; Robotic
1.153
123
Medicine; Surgery; Oncology
Medicine
2,024
40,651,317
Suture-Mediated Patent Fossa Ovalis Closure: Late Clinical Outcomes and Predictors of Technical Success.
JACC. Advances
JACC Adv
4
8
10.1016/j.jacadv.2025.101991
eng
2,025
7
11
2,025
7
11
[BACKGROUND] At short-term follow-up, percutaneous suture-mediated patent fossa ovalis (PFO) closure appears as a safe and effective alternative to device-based methods. This study represents the largest cohort of patients undergoing suture-mediated PFO closure with the longest follow-up reported to date. [OBJECTIVES] ...
patent fossa ovalis; percutaneous closure; predictors; suture
null
null
null
null
null
40,649,069
Bifocal Radial Fracture/Dislocation and Distal Ulnar Fracture-A Rare Case of Proximal Forearm Instability Not Yet Classified and Literature Review.
Journal of clinical medicine
J Clin Med
14
13
10.3390/jcm14134694
eng
2,025
7
2
2,025
7
2
[INTRODUCTION] Monteggia fractures, first described by Giovanni Battista Monteggia, involve a fracture of the proximal ulna with anterior dislocation of the radial head. Bado's 1967 classification divides these injuries into four types. Rare mixed patterns exist, overlapping with other forearm injuries such as Galeazzi...
Bado; Monteggia; forearm fracture; orthopedics; trauma
0.919
132
Medicine
Medicine
2,024
40,647,440
A Multicenter Machine Learning-Based Predictive Model of Acute Toxicity in Prostate Cancer Patients Undergoing Salvage Radiotherapy (ICAROS Study).
Cancers
Cancers (Basel)
17
13
10.3390/cancers17132142
eng
2,025
6
25
2,025
6
25
[BACKGROUND] This study aimed to develop a predictive model for acute gastrointestinal (GI) and genitourinary (GU) toxicity in prostate cancer patients treated with salvage radiotherapy (SRT) post-prostatectomy, using machine learning techniques to identify key prognostic factors. [METHODS] A multicenter retrospective ...
LASSO regression; acute toxicity; androgen-deprivation therapy; gastrointestinal toxicity; genitourinary toxicity; machine learning; planning target volume; predictive model; prostate cancer; salvage radiotherapy
1.462
157
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,647,439
Performance and Prognostic Relevance of Lymph Node Assessment by One-Step Nucleic Acid Amplification Assay in Rectal Cancer: A Multicenter Study.
Cancers
Cancers (Basel)
17
13
10.3390/cancers17132141
eng
2,025
6
25
2,025
6
25
[BACKGROUND/OBJECTIVES] Lymph node metastases (LNM) undetected by standard hematoxylin and eosin (HE) have been associated with unfavorable prognosis in colorectal cancer. The One-Step Nucleic Acid Amplification (OSNA) assay has demonstrated superior sensitivity in detecting LNM compared to HE. We aimed to assess the p...
OSNA; diagnosis; lymph node metastases; prognosis; rectal carcinoma; staging
1.462
157
Oncology; Cancer Research
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,646,686
Design, synthesis, and biological evaluation of novel luteoride A derivatives against phytopathogenic fungi and bacteria.
Pest management science
Pest Manag Sci
null
null
10.1002/ps.70028
eng
2,025
7
11
2,025
7
11
[BACKGROUND] Plant diseases caused by phytopathogenic fungi and bacteria represent a critical barrier to sustainable agriculture, significantly compromising crop yield and quality. Natural products have been a significant source of effective and low-risk pesticides. In this study, a series of novel indole derivatives, ...
antimicrobial activity; complex III; indole; luteoride A; natural product
null
null
null
null
null
40,646,608
Healthcare providers' antenatal physical exercise counseling practice and its associated factors in Southwest Ethiopia: a cross-sectional study.
BMC health services research
BMC Health Serv Res
25
1
10.1186/s12913-025-13085-x
eng
2,025
7
11
2,025
7
11
[BACKGROUND] Scientific evidence has sufficiently proved that antenatal physical exercise benefits maternal, fetal, and child health. Despite the World Health Organization strongly recommends that health care providers advise pregnant women on physical exercise, many of them have reported they didn’t receive any exerci...
Antenatal physical exercise; Associated factors; Healthcare provider
1.174
157
Health Policy
Medicine
2,024
40,646,508
Translation and validation of the Chinese version of the post-intensive care syndrome questionnaire.
BMC nursing
BMC Nurs
24
1
10.1186/s12912-025-03576-x
eng
2,025
7
11
2,025
7
11
[OBJECTIVE] To translate and validate the Post-Intensive Care Syndrome (PICS) Questionnaire for use in Chinese ICU patient populations. [METHODS] Authorization was secured via email from the original author of the questionnaire. Utilizing the Brislin translation model, the questionnaire underwent Sinicization and cultu...
Assessment tool; Post-Intensive care syndrome; Reliability; Validity
1.272
62
Nursing
Nursing
2,024
40,646,438
Impact of the COVID-19 era on preventative primary care for children 0-5 years old: a scoping review.
BMC primary care
BMC Prim Care
26
1
10.1186/s12875-025-02913-y
eng
2,025
7
11
2,025
7
11
[BACKGROUND] Restrictions to routine preventative primary care well child visits (WCV) during COVID-19 may have affected a variety of outcomes for young children including growth, development, and the identification and management of developmental delays. To better understand the effect of the pandemic on these outcome...
Child development; Pandemic; Preventative care; Primary care
1.073
95
Family Practice; Medicine
Medicine
2,024
40,646,359
Safety, feasibility, and effectiveness of exercise interventions in patients with hematologic malignancy during chemotherapy: a systematic review and meta-analysis.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
33
8
10.1007/s00520-025-09748-4
eng
2,025
7
11
2,025
7
11
[PURPOSE] To evaluate the safety, feasibility, and effectiveness of exercise interventions aimed at improving the physical and/or mental health of patients with hematologic malignancies (HM) during chemotherapy. [METHODS] We systematically searched nine electronic databases for studies from their inception up to Februa...
Exercise; Fatigue; Feasibility; Hematologic malignancy; Meta-analysis; Physical fitness; Quality of life; Safety
1.109
143
Oncology; Rehabilitation; Oncology
Medicine; Nursing
2,024
40,645,912
Estimation of the incidence and prevalence of type 1 diabetes mellitus in children under 15 years of age in Spain.
Endocrinologia, diabetes y nutricion
Endocrinol Diabetes Nutr (Engl Ed)
72
7
10.1016/j.endien.2025.501591
eng
2,025
null
null
2,025
7
10
[INTRODUCTION] Epidemiological studies on type 1 diabetes mellitus (DM1) have been developed in almost all the Spanish geography, but no registry currently provides national incidence and prevalence figures. This study aims to estimate the incidence of DM1 in children under 15 years of age in Spain based on the availab...
Autoimmunity; Autoinmunidad; Diabetes tipo 1; Epidemiology; Incidence; Incidencia; Prevalence; Prevalencia; Spain; Type 1 diabetes
0.453
35
Endocrinology, Diabetes and Metabolism; Nutrition and Dietetics; Endocrinology
Biochemistry, Genetics and Molecular Biology; Medicine; Nursing
2,024
40,645,845
Association of sleep patterns with microvascular complications in individuals with type 2 diabetes: A prospective cohort study.
Sleep health
Sleep Health
null
null
10.1016/j.sleh.2025.05.010
eng
2,025
7
10
2,025
7
10
[BACKGROUND] This study aimed to explore the association between sleep patterns and the risk of microvascular complications in patients with type 2 diabetes. [METHODS AND RESULTS] Using UK Biobank data, we included the findings for 19,996 patients with type 2 diabetes who were free of diabetic microvascular complicatio...
Diabetes mellitus, type 2; Diabetic nephropathy; Diabetic neuropathies; Diabetic retinopathy; Sleep
1.285
51
Behavioral Neuroscience; Health; Neuropsychology and Physiological Psychology; Social Sciences
Neuroscience; Psychology; Social Sciences
2,024
40,645,575
Validation of Pedal Acceleration Time for the Assessment of Perfusion in Patients with Chronic Limb-Threatening Ischemia.
Annals of vascular surgery
Ann Vasc Surg
121
null
10.1016/j.avsg.2025.07.014
eng
2,025
7
9
2,025
7
9
[BACKGROUND] Accurate hemodynamic assessment of perfusion is critical in managing patients with chronic limb-threatening ischemia (CLTI). Traditional methods such as ankle-brachial index (ABI) and toe pressures (TPs) may be inadequate due to arterial calcification and toe amputations. Pedal acceleration time (PAT), a n...
null
0.707
87
Cardiology and Cardiovascular Medicine; Medicine; Surgery
Medicine
2,024
40,644,955
Embedding relationships in hope: A qualitative study on the hope experience of patients with colorectal cancer based on Snyder's hope theory.
European journal of oncology nursing : the official journal of European Oncology Nursing Society
Eur J Oncol Nurs
77
null
10.1016/j.ejon.2025.102916
eng
2,025
8
null
2,025
6
6
[PURPOSE] To explore colorectal cancer patients' experiences and feelings of hope, and to analyse their connotations and characteristics, and provide a basis for developing hope-related measures and interventions. [METHODS] This interpretative phenomenological study employed semi-structured interviews outline based on ...
Colorectal Neoplasms; Embedded relationships; Hope; Qualitative study
0.936
74
Medicine; Oncology
Medicine; Nursing
2,024
40,644,859
Chronic kidney disease facilitates TNF-α + neutrophils dysfunction and progression in oral squamous cell carcinoma.
International immunopharmacology
Int Immunopharmacol
162
null
10.1016/j.intimp.2025.115184
eng
2,025
9
23
2,025
7
10
[BACKGROUND AND AIMS] The risk of cancer in patients with chronic kidney disease (CKD), particularly in those on dialysis is high. However, the underlying mechanism remains unclear. Moreover, the involvement of CKD in the progression of oral squamous cell carcinoma (OSCC) is still not fully understood. In this study, w...
Chronic kidney disease; Oral squamous cell carcinoma
1.239
155
Pharmacology; Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,643,319
An evidence gap map of the personalized medicine in bladder cancer.
Personalized medicine
Per Med
null
null
10.1080/17410541.2025.2530918
eng
2,025
7
11
2,025
7
11
[OBJECTIVE] The study aims to develop an Evidence Gap Map (EGM) to summarize the current evidence cited in personalized medicine (PM) in bladder cancer, focusing on systematic reviews and high-level evidence syntheses. [METHODS] The review involved a comprehensive search in databases up to June 2024, and involved a two...
Biomarkers; Personalized medicine; bladder cancer; clinical evidence; evidence gap map; precision oncology; targeted therapy
0.459
38
Medicine; Molecular Medicine; Pharmacology
Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,643,171
Bidirectional two-sample Mendelian randomization analysis reveals a causal effect of chronic pain on chronic kidney diseases and renal function.
Clinical nephrology
Clin Nephrol
null
null
10.5414/CN111662
eng
2,025
7
11
2,025
7
11
[OBJECTIVE] A growing body of research has shown a connection between chronic pain and chronic kidney disease (CKD). However, it is unclear if these correlations point to a cause-and-effect link. Our goal is to investigate the causal link between renal function or CKD and chronic pain. [MATERIALS AND METHODS] Using gen...
null
null
null
null
null
null
40,643,141
Lamina-preserving, Type II Posterior Column Osteotomies (PCOs) for Correction of Adult (Thoraco) Lumbar Scoliosis.
Clinical spine surgery
Clin Spine Surg
null
null
10.1097/BSD.0000000000001872
eng
2,025
7
11
2,025
7
11
[STUDY DESIGN] Operative video and supplemental manuscript. [OBJECTIVE] To present a step-by-step approach to performing lamina-preserving lumbar posterior column osteotomies (PCO) for correction of adult thoracolumbar scoliosis. [SUMMARY OF BACKGROUND DATA] Outcomes of operations for adult thoracolumbar spinal deformi...
Ponte osteotomy; Smith-Petersen osteotomy; adult scoliosis; interlaminar fusion; posterior column osteotomy; thoracolumbar
0.774
45
Surgery; Neurology; Orthopedics and Sports Medicine
Medicine
2,024
40,642,892
Inavolisib for HR-Positive, HER2-Negative Advanced Breast Cancer: Clinical Trials and Patient Access Implication.
American journal of clinical oncology
Am J Clin Oncol
null
null
10.1097/COC.0000000000001209
eng
2,025
7
11
2,025
7
11
[OBJECTIVES] Breast cancer remains the most prevalent cancer among women in the United States, with hormone receptor-positive (HR+) and HER2-negative subtypes comprising a significant proportion of cases. Despite advancements in treatment, resistance to endocrine therapies remains a substantial clinical challenge, espe...
PIK3CA mutation; advanced breast cancer; clinical trials; inavolisib; patient access
0.696
93
Cancer Research; Oncology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,642,844
Considerations of Fertility in Elite Sportswomen: A Narrative Review.
BJOG : an international journal of obstetrics and gynaecology
BJOG
null
null
10.1111/1471-0528.18283
eng
2,025
7
11
2,025
7
11
[BACKGROUND] Increasingly more women are participating in professional and recreational sports. Whilst vigorous intensity physical activity is considered beneficial, evidence demonstrates higher rates of menstrual disturbance in elite athletes. There is less clear evidence on the impact of elite-level exercise on ferti...
assisted reproduction; athlete; exercise; fertility; in vitro fertilisation; menstrual disorder; sportswoman
1.786
195
Obstetrics and Gynecology
Medicine
2,024
40,642,293
Exercise delays aging: evidence from telomeres and telomerase -a systematic review and meta-analysis of randomized controlled trials.
Frontiers in physiology
Front Physiol
16
null
10.3389/fphys.2025.1627292
eng
2,025
null
null
2,025
6
26
[OBJECTIVE] To systematically evaluate the regulatory effects of exercise intervention on telomere length (TL) and telomerase activity (TA), and to provide evidence for formulating precise exercise prescriptions based on telomere protection. [METHODS] Databases including China National Knowledge Infrastructure, Wanfang...
aging; exercise; meta analysis; telomerase; telomeres
1.023
175
Physiology; Physiology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,642,236
Global burden of alcoholic cardiomyopathy in middle-aged men (1990-2021) and projections to 2050: a systematic analysis of the Global Burden of Disease 2021 data.
Frontiers in public health
Front Public Health
13
null
10.3389/fpubh.2025.1608351
eng
2,025
null
null
2,025
6
26
[OBJECTIVE] Alcoholic cardiomyopathy (ACM) is a severe cardiovascular condition caused by chronic excessive alcohol consumption, leading to heart failure, increased morbidity, and mortality. This study aimed to comprehensively analyze the global burden of ACM among middle-aged males from 1990 to 2021 using the Global B...
Global Burden of Disease; alcoholic cardiomyopathy; disability-adjusted life years; epidemiology; forecasting; mortality
1.027
119
Public Health, Environmental and Occupational Health
Medicine
2,024
40,642,167
Low prognostic nutritional index predicts poor outcome in newly diagnosed angioimmunoblastic T-cell lymphoma.
Frontiers in nutrition
Front Nutr
12
null
10.3389/fnut.2025.1622691
eng
2,025
null
null
2,025
6
26
[BACKGROUND] Angioimmunoblastic T-cell lymphoma (AITL) is a rare subtype of peripheral T-cell lymphoma, characterized by an aggressive disease course and poor prognosis. The prognostic nutritional index (PNI), which reflects nutritional and immune status, has emerged as a potential prognostic factor in various cancers....
albumin; angioimmunoblastic T-cell lymphoma; lymphocyte; prognosis; prognostic nutritional index; risk models
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
40,641,732
Assessing Vascular Biomarkers and Their Association with Hypertension in Paediatric Chronic Kidney Disease.
Sultan Qaboos University medical journal
Sultan Qaboos Univ Med J
25
1
10.18295/squmj.10.2024.056
eng
2,025
5
2
null
null
null
[OBJECTIVES] This study aimed to examine the correlation between children with chronic kidney disease (CKD) and endothelial dysfunction biomarkers, including asymmetric dimethylarginine (ADMA), angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A), as well as blood pressure and cardiovascular risk. [...
Cardiovascular Risk; Cells; Chronic Renal Failure; Egypt; Hypertension; Vascular Endothelial Growth Factor; Vascular Remodeling: Biomarkers
0.391
38
Medicine
Medicine
2,024
40,641,715
Evidence-Based Medicine: Knowledge, attitudes and practices among senior medical students and interns in Oman.
Sultan Qaboos University medical journal
Sultan Qaboos Univ Med J
25
1
10.18295/2075-0528.2857
eng
2,025
5
2
null
null
null
[OBJECTIVES] Evidence-based medicine (EBM) provides a systematic method for navigating an extensive repository of information and making well-informed judgements regarding patient care. This study aimed to evaluate the clinical knowledge, attitudes and practices related to EBM among medical students and interns in Oman...
Attitudes; Evidence-Based Medicine; Health Knowledge; Internship and Residency; Medical Education; Oman; Practice; Surveys and Questionnaires
0.391
38
Medicine
Medicine
2,024
40,641,607
Analysis of surgical complications and risk factors in genital feminization surgery: a retrospective cohort study of 407 transgender women.
Sexual medicine
Sex Med
13
3
10.1093/sexmed/qfaf045
eng
2,025
6
null
2,025
7
10
[BACKGROUND] Penile inversion vulvo-vaginoplasty with addition of a scrotal skin graft is a widely used technique in genital feminizing surgery for trans women. [AIM] To identify the types and frequencies of complications following genital feminizing surgery and assess associated risk factors. [METHODS] A retrospective...
genital feminizing surgery; genital reassignment; genital reconstruction; transwoman; vulvo-vaginoplasty
0.654
36
Dermatology; Psychiatry and Mental Health; Reproductive Medicine; Urology; Behavioral Neuroscience; Endocrinology; Endocrinology, Diabetes and Metabolism
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
40,641,594
The Effect of Minimal-Dose S-Ketamine Administration Post-Surgery on Opioids Consumption and Functional Rehabilitation Exercises in Patients Undergoing Minimally Invasive Radical Resection of Esophageal Cancer.
Therapeutics and clinical risk management
Ther Clin Risk Manag
21
null
10.2147/TCRM.S527262
eng
2,025
null
null
2,025
7
5
[STUDY OBJECTIVE] To examine the impact of minimal-dose S-ketamine on postoperative analgesia in patients undergoing minimally invasive radical resection for esophageal cancer, with a focus on reducing opioid consumption, enhancing analgesic quality, and facilitating postoperative recovery. [METHODS] A total of 216 pat...
S-ketamine; esophageal cancer; minimal dose; postoperative analgesia
0.699
74
Pharmacology, Toxicology and Pharmaceutics; Safety Research; Chemical Health and Safety; Medicine; Pharmacology
Chemical Engineering; Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences
2,024
40,641,541
Comparative Assessments of PET and ASL MR Perfusion in the Evaluation of Early Dementia.
Acta medica Lituanic
Acta Med Litu
32
1
10.15388/Amed.2025.32.1.10
eng
2,025
null
null
2,025
2
18
[BACKGROUND] Overtly morbid dementing diseases have a prodromal MCI (mild cognitive impairment) phase which is crucial to recognize. Clinical scores provide an easy bedside assessment tool for holistic cognitive evaluation but fail to provide lead time. While routine biomarkers of brain atrophy are late to appear, non-...
MRI; dementia; neurodegeneration
null
null
null
null
null
40,641,539
Neuropsychiatric Manifestations of Lyme Disease: A Literature Review of Psychiatric and Cognitive Impacts.
Acta medica Lituanic
Acta Med Litu
32
1
10.15388/Amed.2025.32.1.17
eng
2,025
null
null
2,025
2
18
[BACKGROUND] Lyme disease can lead to neuropsychiatric symptoms like depression, anxiety, and cognitive issues, often mimicking primary psychiatric disorders. This paper examines the connection between Lyme disease and neuropsychiatric outcomes to improve diagnosis and treatment. [MATERIALS AND METHODS] The PubMed data...
Lyme disease; borreliosis; neuropsychiatric symptoms; psychiatric disorders
null
null
null
null
null
40,641,160
Management of analgesia in cardiac surgery.
Pain management
Pain Manag
null
null
10.1080/17581869.2025.2532359
eng
2,025
7
10
2,025
7
10
[BACKGROUND] Pain management in cardiac surgery remains a critical component of perioperative care, influencing recovery, patient satisfaction, and outcomes. Traditional opioid-based analgesia is associated with significant adverse effects, prompting the exploration of multimodal strategies, including regional anesthes...
Cardiac surgery; ERAS; analgesia; perioperative management; regional anesthesia
null
null
null
null
null
40,640,996
Scattering as part of the protection afforded by nanoparticulate filters - An example with tris-biphenyl triazine.
International journal of cosmetic science
Int J Cosmet Sci
null
null
10.1111/ics.70001
eng
2,025
7
10
2,025
7
10
[OBJECTIVE] Tris-biphenyl triazine (TBPT) is an organic nanoparticulate UV filter for use in sunscreens. Thanks to its chemical structure and particulate properties, the effectiveness of TBPT is associated with both absorption and scattering processes. In our study, we evaluated how much of the UV protection of TBPT is...
UV protection; absorbance; scattering
0.694
83
Chemistry; Colloid and Surface Chemistry; Dermatology; Drug Discovery; Pharmaceutical Science; Aging
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,640,960
Family-related adversity and positive youth development: the role of psychological distress, hopelessness and hostility.
BMC psychology
BMC Psychol
13
1
10.1186/s40359-025-03098-w
eng
2,025
7
10
2,025
7
10
[BACKGROUND] The family is a very important institution that provides relationships and contexts for adolescents and can activate a trajectory of their positive development. Family-related adversity can endanger this development via associated negative emotions, such as feelings of hopelessness, hostility, and psycholo...
Family-related adversity; Hopelessness; Hostility; Positive youth development; Psychological distress
1.03
49
Medicine; Psychology
Medicine; Psychology
2,024
40,640,927
Exploring factors that shaped Syrian refugees integration into Lebanon's national health system using Kingdon's Multiple Streams Framework.
Conflict and health
Confl Health
18
Suppl 1
10.1186/s13031-025-00680-2
eng
2,025
7
10
2,025
7
10
[BACKGROUND] Since the start of the Syrian conflict in 2011, neighboring country Lebanon has hosted the largest number of refugees per capita in the world. To meet refugees' health care needs, Lebanon adopted an integrated model of care. This paper explores the key factors and events that have shaped the policy on the ...
Health system; Lebanon; Policy analysis; Refugees
1.392
51
Health; Public Health, Environmental and Occupational Health
Medicine; Social Sciences
2,024
40,640,899
Differences in macrophage pyroptosis and polarization induced by nano-/micro-calcium oxalate crystals.
Journal of nanobiotechnology
J Nanobiotechnology
23
1
10.1186/s12951-025-03549-x
eng
2,025
7
10
2,025
7
10
[OBJECTIVE] This study aimed to compare the differences in pyroptosis and polarization of macrophages induced by different sizes of calcium oxalate monohydrate (COM) crystals and discuss the mechanism of kidney stone formation. [METHODS] COM crystals with sizes of about 100 nm, 500 nm, 2.5 μm, and 10 μm were synthesize...
Calcium oxalate crystals; Inflammation; Macrophages; Polarization; Pyroptosis
2.282
125
Applied Microbiology and Biotechnology; Bioengineering; Biomedical Engineering; Medicine; Molecular Medicine; Nanoscience and Nanotechnology; Pharmaceutical Science
Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Engineering; Immunology and Microbiology; Materials Science; Medicine; Pharmacology, Toxicology and Pharmaceutics
2,024
40,640,893
Exosomes derived from hypoxia-preconditioned M2 macrophages alleviate degeneration in knee osteoarthritis through the miR‑124‑3p/STAT3 axis.
Journal of translational medicine
J Transl Med
23
1
10.1186/s12967-025-06808-5
eng
2,025
7
10
2,025
7
10
[BACKGROUND] M2 macrophages-derived exosomes (M2φ-Exos) have been demonstrated to effectively alleviate osteoarthritis (OA) in animal models. Hypoxic preconditioning is commonly used to enhance the biological effects of stem cell-derived exosomes, but its impact on M2φ-Exos remains unclear. This study aims to investiga...
Exosomes; Hypoxic preconditioning; M2 macrophages; Osteoarthritis; STAT3; miR-124-3p
1.997
153
Biochemistry, Genetics and Molecular Biology; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,640,881
Preconception health beliefs and intentions predict behaviours among expectant male partners: a cross-sectional study.
Archives of public health = Archives belges de sante publique
Arch Public Health
83
1
10.1186/s13690-025-01627-y
eng
2,025
7
10
2,025
7
10
[BACKGROUND] The preconception period allows couples to plan and prepare for pregnancy. However, males can often consider this integral public health topic as a female domain. To better understand and support behaviour change for males before conception, this study aimed to identify and explore the preconception and pr...
Beliefs; Intentions; Male; Preconception; Pregnancy planning
null
null
null
null
null
40,640,857
Shifting epidemic trends and severity in pediatric Mycoplasma pneumoniae infections in the post-COVID-19 era.
Italian journal of pediatrics
Ital J Pediatr
51
1
10.1186/s13052-025-02064-x
eng
2,025
7
10
2,025
7
10
[BACKGROUND] While non-pharmaceutical interventions (NPIs) implemented for COVID-19 have been shown to affect the epidemiology of respiratory pathogens, the impact of China's prolonged NPIs on Mycoplasma pneumoniae (MP) remains unclear. This study aimed to analyze the MP test positivity rates, as well as assessing dise...
COVID-19; Clinical severity; Epidemic trends; Mycoplasma pneumoniae; Non-pharmaceutical interventions
0.836
65
Pediatrics, Perinatology and Child Health
Medicine
2,024
40,640,805
The Mirror of Erised: a retrospective population-wide study of Czech all-cause mortality data by COVID-19 vaccination status.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-23619-x
eng
2,025
7
10
2,025
7
10
[BACKGROUND] In this study, we investigated the association between COVID-19 vaccination status and all-cause mortality (ACM) rate in the population of the Czech Republic between January 2020 and December 2022. [METHODS] In this retrospective study based on official population-wide individual (record-level) data, we an...
All-cause mortality; COVID-19; Healthy user bias; Healthy vaccinee effect; Individual-level data; Vaccination status; Vaccine effectiveness
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,640,750
Exploring and evaluating the in vitro antifungal, antibiofilm and antitoxin efficacy of Artabotrys brachypetalus Benth. against Candida spp. and its toxicity in vivo assays.
BMC complementary medicine and therapies
BMC Complement Med Ther
25
1
10.1186/s12906-025-04877-z
eng
2,025
7
10
2,025
7
10
[BACKGROUND] Given the few studies found in the literature and the search for new substances with antifungal and antivirulence activities against Candida spp., the use of natural products provides us with an effective treatment of infections with minimized side effects. This study was aimed at evaluating the toxicity a...
A. brachypetalus; Candida spp.; Antifungal activity; Antivirulence; Biofilm; Hemolytic; Phospholipase; Proteinase
0.741
123
Complementary and Alternative Medicine
Medicine
2,024
40,640,641
Enhancing decision-making strategies in treatment for unruptured intracranial aneurysms: a novel analytical approach using PHASES, ELAPSS and UIATS scores for microsurgical clipping outcome prediction.
Neurosurgical review
Neurosurg Rev
48
1
10.1007/s10143-025-03683-y
eng
2,025
7
11
2,025
7
11
[OBJECTIVE] The management of unruptured intracranial aneurysms (UIA) is complex, balancing the risks of surgical intervention against aneurysm rupture. The PHASES, ELAPSS, and UIATS scoring systems have been developed to assist in clinical decision-making, but their efficacy in predicting surgical outcome remains uncl...
ELAPSS score; PHASES score; Predictive analysis; Surgical outcome; UIATS score; Unruptured intracranial aneurysms
0.978
77
Medicine; Surgery; Neurology
Medicine
2,024
40,640,628
First use of augmented reality headset in minimally invasive general surgery: seeing is believing.
Surgical endoscopy
Surg Endosc
null
null
10.1007/s00464-025-11985-x
eng
2,025
7
10
2,025
7
10
[BACKGROUND] Augmented reality (AR) is an evolving technology with the potential to transform surgical practice. By superimposing digital information onto the surgeon's field of view, AR headsets provide an unobstructed view of the minimally invasive operative field, eliminating the need to divert attention to external...
Augmented reality; Endoscopy; Laparoscopy; Minimally invasive surgery; Spatial computing
1.023
178
Surgery
Medicine
2,024
40,640,618
A comparison of high efficiency and traditional benign anorectal operating room days: a cohort study.
Surgical endoscopy
Surg Endosc
null
null
10.1007/s00464-025-11956-2
eng
2,025
7
10
2,025
7
10
[BACKGROUND] High efficiency (HE) operating rooms (OR) describe the intentional grouping of surgical cases according to case complexity, anesthetic, and nursing requirement. This approach has the potential to increase case volumes while protecting patient outcomes. [OBJECTIVE] Comparison of a HE to a Traditional model ...
Benign anorectal; Cost reduction; High efficiency; Quality improvement
1.023
178
Surgery
Medicine
2,024
40,640,428
Association between sleep quality and life satisfaction and self-efficacy among women with gynecological cancer in West China: A cross-sectional study.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Support Care Cancer
33
8
10.1007/s00520-025-09734-w
eng
2,025
7
11
2,025
7
11
[OBJECTIVE] To estimate the sleep quality in patients with gynecological cancer and to determine the association between sleep quality and life satisfaction, self-efficacy, and clinical and demographic factors. [METHODS] A cross-sectional online survey was conducted at a tertiary hospital in Chengdu, China, involving a...
Gynecological cancer; Pittsburgh sleep quality index (PSQI); Satisfaction with life; Self-efficacy; Sleep quality
1.109
143
Oncology; Rehabilitation; Oncology
Medicine; Nursing
2,024
40,640,020
Preliminary Data on Cortical and Acoustical Correlates of Voice Training Under Internal vs External Focus of Attention Conditions.
Journal of voice : official journal of the Voice Foundation
J Voice
null
null
10.1016/j.jvoice.2025.06.013
eng
2,025
7
9
2,025
7
9
[PURPOSE] Prior research has emphasized the superiority of an external focus of attention for motor learning. According to the Constrained Action Hypothesis, an external focus encourages automaticity by directing attention to movement outcomes, while an internal focus is thought to impair learning by promoting controll...
null
0.573
114
LPN and LVN; Otorhinolaryngology; Speech and Hearing
Health Professions; Medicine; Nursing
2,024
40,640,002
Leveraging NSQIPP testicular torsion process measures: Initial survey of the NSQIPP testicular torsion collaborative.
Journal of pediatric urology
J Pediatr Urol
null
null
10.1016/j.jpurol.2025.06.030
eng
2,025
6
25
2,025
6
25
[BACKGROUND] Testicular torsion is a pediatric emergency that poses a time-sensitive risk to the testicle. Best practices for testicular torsion protocols remain unclear. We convened the Testicular Torsion Collaborative, leveraging National Surgical Quality Improvement Program Pediatric (NSQIPP) Testicular Torsion Proc...
Quality improvement; Testis; Torsion
0.75
63
Pediatrics, Perinatology and Child Health; Urology
Medicine
2,024
40,639,927
Alzheimer's disease basics: we all should know.
Neurological research
Neurol Res
null
null
10.1080/01616412.2025.2529560
eng
2,025
7
10
2,025
7
10
[BACKGROUND] Alzheimer's disease (AD) is the most common cause of dementia worldwide, affecting over 55 million individuals and projected to rise drastically in the coming decades. Characterized by progressive cognitive decline and memory impairment, AD involves complex pathological mechanisms including amyloid-beta (A...
amyloid-beta; dementia; neurodegeneration; tau
0.549
88
Medicine; Neurology; Neurology
Medicine; Neuroscience
2,024
40,639,546
Longitudinal measurement invariance of EURO-D scale across 27 countries in SHARE wave 8 and wave 9: A cross-country alignment study.
Journal of affective disorders
J Affect Disord
390
null
10.1016/j.jad.2025.119852
eng
2,025
7
8
2,025
7
8
[BACKGROUND] The EURO-D is a widely used measure of 12 depressive symptoms among middle-aged and older adults in Europe. The present study aims to evaluate the psychometric properties and measurement invariance of EURO-D across gender, age, time, and countries. [METHODS] This study utilized population-representative sa...
Alignment; Depressive symptoms; Europe; Measurement invariance; Older adults; SHARE
2.121
245
Clinical Psychology; Psychiatry and Mental Health
Medicine; Psychology
2,024
40,639,230
Menopausal stage transitions and associations with overall and domain-specific perceived stress in middle-aged Korean women.
Maturitas
Maturitas
200
null
10.1016/j.maturitas.2025.108660
eng
2,025
7
5
2,025
7
5
[BACKGROUND] The menopausal transition, closely linked to later-life health, involves substantial physiological and psychological changes, potentially increasing perceived stress. However, longitudinal studies have reported inconsistent results, with limited data for Asian women, despite the potential for perceived str...
Menopausal transition; Menopause; Middle-aged Korean women; Perceived stress inventory; Straw+10
1.218
136
Biochemistry, Genetics and Molecular Biology; Obstetrics and Gynecology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,639,138
Exploring Humanities Education in Chinese Dental Schools: Perspectives From Faculty Members and Students.
International dental journal
Int Dent J
75
5
10.1016/j.identj.2025.100868
eng
2,025
7
9
2,025
7
9
[OBJECTIVE] To evaluate the status quo of humanities education in Chinese dental institutions and identify improvement areas. [METHODS] A nationwide cross-sectional study across 20 representative Chinese dental institutions employed survey questionnaires developed through literature review and expert consultations. The...
Curriculum; Dental education; Empathy; Humanities education
0.972
81
Dentistry
Dentistry
2,024
40,638,458
Does gastrostomy make a difference in children with congenital Zika syndrome growth?
Revista da Associacao Medica Brasileira (1992)
Rev Assoc Med Bras (1992)
71
6
10.1590/1806-9282.20241670
eng
2,025
null
null
2,025
7
7
[INTRODUCTION] Children diagnosed with congenital Zika syndrome often experience stomatognathic disorders that may compromise caloric intake via oral feeding. [OBJECTIVE] The aim of this study was to assess the effects of gastrostomy on the growth and nutritional parameters of children with congenital Zika syndrome. [M...
null
0.319
51
Medicine
Medicine
2,024
40,637,961
Complications in vertebral body tethering: what are the short term effects on patient reported outcomes?
Spine deformity
Spine Deform
null
null
10.1007/s43390-025-01107-x
eng
2,025
7
10
2,025
7
10
[INTRODUCTION] Vertebral body tethering (VBT) has continued to gain popularity for the treatment of idiopathic scoliosis (IS); however, complication and reoperation rates have been reported as high as 25%. There is a paucity of data on the clinical and long-term outcomes of VBT. The purpose of this study is to determin...
Complications; Short term results; Vertebral body tethering
0.778
41
Orthopedics and Sports Medicine
Medicine
2,024
40,688,293
Nutritional status of patients with driver gene mutation-negative non-small cell lung cancer after postoperative adjuvant chemotherapy.
Journal of thoracic disease
J Thorac Dis
17
6
10.21037/jtd-2025-822
eng
2,025
6
30
2,025
6
17
[BACKGROUND] Non-small cell lung cancer (NSCLC) remains a significant challenge for public health and is closely associated with malnutrition; however, few studies have attempted to examine the malnutrition experienced by patients with driver gene-negative NSCLC who have undergone combined chemotherapy after surgery. T...
Non-small cell lung cancer (NSCLC); diagnostic efficacy; negative for driver gene mutations; prognostic nutritional index
0.624
95
Pulmonary and Respiratory Medicine
Medicine
2,024
40,687,685
Risk of fracture with sodium-glucose cotransporter-2 inhibitors in patients with type 2 diabetes: an updated meta-analysis of randomized controlled trials.
International journal of physiology, pathophysiology and pharmacology
Int J Physiol Pathophysiol Pharmacol
17
3
10.62347/EGNK3393
eng
2,025
null
null
2,025
6
15
[BACKGROUND] Type 2 diabetes mellitus (T2DM) increases the risk of fractures. This meta-analysis compared the effects of sodium-glucose cotransporter-2 inhibitors (SGLT-2i) and dipeptidyl peptidase-4 inhibitors (DPP-4i) on fracture risk in patients with T2DM. [METHOD] A systematic search of PubMed, Web of Science, Emba...
Type 2 diabetes mellitus; cohort studies; dipeptidyl peptidase-4 inhibitors; elderly patients; fracture risk; sodium-glucose cotransporter-2 inhibitors
null
null
null
null
null
40,687,564
Association between red blood cell distribution width-to-albumin ratio and in-hospital mortality in patients with congestive heart failure combined with chronic kidney disease.
Frontiers in cardiovascular medicine
Front Cardiovasc Med
12
null
10.3389/fcvm.2025.1563512
eng
2,025
null
null
2,025
7
4
[BACKGROUND] This study aimed to explore the relationship between the blood cell distribution width-to-albumin ratio (RAR) and in-hospital mortality in patients with congestive heart failure (CHF) combined with chronic kidney disease (CKD). [METHODS] The patients' information was collected from the Medical Information ...
blood cell distribution width-to-albumin ratio; in-hospital mortality; machine learning algorithms; mediation analysis
0.975
81
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,687,547
Prevalence and Genotype Distribution of Human Papillomavirus Among Males in Shantou, China (2019-2023).
Health science reports
Health Sci Rep
8
7
10.1002/hsr2.71094
eng
2,025
7
null
2,025
7
18
[BACKGROUND AND AIMS] Human papillomavirus (HPV) is one of the most prevalent sexually transmitted infections globally, posing significant public health challenges. However, research in China has largely focused on female populations, with limited data on male HPV prevalence and genotype distribution. This study aims t...
China; HPV genotyping; HPV prevalence; Shantou; epidemiology of HPV in males; human papillomavirus
0.567
26
Medicine
Medicine
2,024
40,687,323
Endoscopic Biliary Drainage in Malignant Biliary Strictures: A Prospective Analysis Based on Real-World Data.
Gastroenterology research
Gastroenterology Res
18
4
10.14740/gr2046
eng
2,025
8
null
2,025
6
16
[BACKGROUND] Endoscopic biliary drainage has emerged as the standard treatment for palliative drainage in malignant biliary strictures (MBS). [METHODS] This prospective study aimed to investigate the outcomes of patients diagnosed with MBS who underwent biliary drainage through endoscopic retrograde cholangiopancreatog...
Biliary stricture; Cholangiocarcinoma; Endoscopic stenting; Malignant
null
1
Gastroenterology
Medicine
2,024
40,687,310
Beyond the consult: Outcomes following pediatric VAD referral.
JHLT open
JHLT Open
9
null
10.1016/j.jhlto.2025.100318
eng
2,025
8
null
2,025
6
20
[BACKGROUND] Little is known about patients who are referred for ventricular assist device (VAD) therapy but not implanted. The purpose of this study is to describe their outcomes at 1-year post initial consultation. [METHODS] Retrospective analysis for patients referred to our VAD services between 01/2019 and 12/2023....
Cardiomyopathy; Congenital heart disease; Pediatrics; Referral timing; Ventricular assist device
null
null
null
null
null
40,687,206
Biomechanical analysis of retroperitoneal 360° anterior lumbar interbody hybrid stabilization constructs for degenerative conditions: A finite element investigation.
Journal of orthopaedics
J Orthop
67
null
10.1016/j.jor.2025.06.034
eng
2,025
9
null
2,025
7
7
[BACKGROUND] Segmental fusion utilizing interbody cages and pedicle screw fixation (PSF) remains the predominant surgical intervention for managing chronic low back pain. However, the biomechanical efficacy of combining anterior interbody cages with hybrid stabilization techniques, particularly in the context of retrop...
Adjacent segment disease; Cage subsidence; Finite element model; Fusion; Hybrid stabilization; Interbody cage; Lumbosacral spine
0.67
41
Orthopedics and Sports Medicine
Medicine
2,024
40,687,147
Integrated Single-Cell and Spatial Transcriptomic Analysis Identifies ISR-Related Genes Driving Immune Regulation in Parkinson's Disease.
Journal of inflammation research
J Inflamm Res
18
null
10.2147/JIR.S521744
eng
2,025
null
null
2,025
7
15
[BACKGROUND] Parkinson's disease (PD) is a progressive neurodegenerative disorder marked by motor dysfunction and dopaminergic neuron loss. Although its genetic and molecular underpinnings have been increasingly studied, the pathways driving PD progression remain unclear. The integrated stress response (ISR), a conserv...
DDIT4; bioinformatics; integrated stress response; single-cell transcriptomics; spatial transcriptomics
1.14
58
Immunology; Immunology and Allergy
Immunology and Microbiology; Medicine
2,024
40,687,115
Gait and balance dysfunction are associated with cognitive performance only in men with Parkinson's disease.
Clinical parkinsonism & related disorders
Clin Park Relat Disord
13
null
10.1016/j.prdoa.2025.100363
eng
2,025
null
null
2,025
7
5
[INTRODUCTION] Parkinson's disease (PD) can cause locomotor dysfunction and cognitive impairment and these symptoms are often associated. This study assesses relationships between comprehensive cognitive performance and locomotor function domains: gait, balance, and mobility, in men and women with PD. [METHODS] Sixty P...
null
null
null
null
null
null
40,686,851
Not so great expectations: The role of price and name information in the nocebo effect.
Exploratory research in clinical and social pharmacy
Explor Res Clin Soc Pharm
19
null
10.1016/j.rcsop.2025.100630
eng
2,025
9
null
2,025
6
28
[BACKGROUND] The perception of taking a generic medication can result in reduced efficacy and increased side effects, despite equivalence to brand name medications under double blind conditions. It may be that cues typically associated with generics, including lower price and more complex name, exacerbate negative expe...
Drug names; Expectations; Generic medication; Nocebo effect; Price; Side effects
0.514
12
Pharmacy; Health, Toxicology and Mutagenesis; Pharmacology
Environmental Science; Health Professions; Medicine
2,024
40,686,723
Bibliometric analysis of colchicine in cardiovascular health: trends, key contributors, and global collaborations.
Turkish journal of medical sciences
Turk J Med Sci
55
3
10.55730/1300-0144.6003
eng
2,025
null
null
2,025
3
26
[BACKGROUND/AIM] The study aims to systematically analyze the body of literature concerning the effects of colchicine on the cardiovascular system, providing a comprehensive evaluation of the current knowledge and highlighting the clinical and scientific relevance of colchicine in this field. [MATERIALS AND METHODS] Da...
Colchicine; bibliometric analysis; cardiovascular health
0.386
44
Medicine
Medicine
2,024
40,686,715
Short-term efficacy and safety of nondamaging retinal laser therapy for retinitis pigmentosa-associated cystoid macular edema.
Turkish journal of medical sciences
Turk J Med Sci
55
3
10.55730/1300-0144.6012
eng
2,025
null
null
2,025
4
17
[BACKGROUND/AIM] To evaluate the short-term efficacy and safety of nondamaging retinal laser therapy (NRT) for retinitis pigmentosa-associated cystoid macular edema (RP-CME) and analyze anatomical and functional outcomes. [MATERIALS AND METHODS] A retrospective case series of 40 eyes from 30 patients with RP-CME was co...
Retinitis pigmentosa; central macular thickness; cystoid macular edema; micropulse laser; nondamaging retinal laser therapy; visual acuity
0.386
44
Medicine
Medicine
2,024
40,686,704
Medicolegal evaluation of pediatric patients with injection neuropathy.
Turkish journal of medical sciences
Turk J Med Sci
55
3
10.55730/1300-0144.6021
eng
2,025
null
null
2,025
4
28
[BACKGROUND/AIM] Injection neuropathy (IN) is a rare but preventable form of iatrogenic nerve injury, particularly affecting the sciatic nerve when intramuscular injections are administered incorrectly. While IN is uncommon in high-income countries, it remains a significant public health issue in Türkiye, especially in...
Injection neuropathy; children; diclofenac sodium; forensic medicine; malpractice; sciatic nerve injury
0.386
44
Medicine
Medicine
2,024
40,686,449
Artificial intelligence in radiology: diagnostic sensitivity of ChatGPT for detecting hemorrhages in cranial computed tomography scans.
Diagnostic and interventional radiology (Ankara, Turkey)
Diagn Interv Radiol
null
null
10.4274/dir.2025.253456
eng
2,025
7
21
2,025
7
21
[PURPOSE] Chat Generative Pre-trained Transformer (ChatGPT)-4V, a large language model developed by OpenAI, has been explored for its potential application in radiology. This study assesses ChatGPT-4V's diagnostic performance in identifying various types of intracranial hemorrhages in non-contrast cranial computed tomo...
Artificial intelligence; ChatGPT; computed tomography; hematoma; intracranial hemorrhages
0.478
57
Radiology, Nuclear Medicine and Imaging; Cardiology and Cardiovascular Medicine
Medicine
2,024
40,686,277
Dynamics of Oxygen Reserve Index and Arterial Oxygen Partial Pressure in Children: A Prospective Observational Study.
Paediatric anaesthesia
Paediatr Anaesth
null
null
10.1111/pan.70014
eng
2,025
7
21
2,025
7
21
[AIMS] The Oxygen Reserve Index (ORI) is a novel, noninvasive parameter that reflects moderate hyperoxic states. However, its relationship with PaO2 in the pediatric population remains poorly understood. We investigated the ORI-PaO2 relationship during pediatric cardiac surgery and identified its influencing factors. [...
arterial oxygen partial pressure; cardiac surgery; children; hyperoxia; oxygen reserve index
0.658
102
Anesthesiology and Pain Medicine; Pediatrics, Perinatology and Child Health
Medicine
2,024
40,686,216
Lung Single-Cell Transcriptomics Reveal Diverging Pathobiology and Opportunities for Precision Targeting in Scleroderma-Associated Versus Idiopathic Pulmonary Arterial Hypertension.
Circulation. Genomic and precision medicine
Circ Genom Precis Med
null
null
10.1161/CIRCGEN.124.004936
eng
2,025
7
21
2,025
7
21
[BACKGROUND] Pulmonary arterial hypertension (PAH) involves progressive cellular and molecular change within the pulmonary vasculature, leading to increased vascular resistance. Current therapies targeting nitric oxide, endothelin, and prostacyclin pathways yield variable treatment responses. Patients with systemic scl...
apoptosis; fibroblasts; lung; nitric oxide; transcriptome
null
null
null
null
null
40,685,062
Navigating an unexpected creatinine result during a pre-intravenous contrast renal function workup.
Clinical biochemistry
Clin Biochem
139
null
10.1016/j.clinbiochem.2025.110979
eng
2,025
7
18
2,025
7
18
[BACKGROUND] Increasing chronic disease incidence drives intravenous (IV) contrast-based diagnostic imaging. While IV procedure is largely safe, contrast-induced neuropathy risk in patients with predisposing factors demand pre-IV renal assessment. Although common, point-of-care creatinine (POC) tests are prone to gener...
Creatinine; IV contrast; Index of individuality; Patient-centered metrics; Reference change value; Renal assessment; Subject-based reference interval
0.613
130
Clinical Biochemistry; Medicine
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,683,963
Longitudinal study of risk factors predicting cannabis use disorder in UK young adults and adolescents.
Communications medicine
Commun Med (Lond)
5
1
10.1038/s43856-025-01018-y
eng
2,025
7
19
2,025
7
19
[BACKGROUND] Cannabis use disorder (CUD) affects up to 1 in 5 people who try cannabis. In order to develop effective interventions to prevent and treat CUD, it is important to identify the factors that predict it. This longitudinal study investigated whether eight potential risk factors predicted CUD levels at 12-month...
null
2.098
28
Assessment and Diagnosis; Epidemiology; Internal Medicine; Medicine; Public Health, Environmental and Occupational Health
Medicine; Nursing
2,024
40,683,770
Real-World Evidence on Outcomes and Safety of Ropeginterferon Alfa-2b in Patients With Myeloproliferative Neoplasms: A Retrospective Cohort Study.
Clinical lymphoma, myeloma & leukemia
Clin Lymphoma Myeloma Leuk
null
null
10.1016/j.clml.2025.06.011
eng
2,025
6
25
2,025
6
25
[BACKGROUND] Ropeginterferon alfa-2b-njft (ropegIFN) has demonstrated superior efficacy over hydroxyurea in polycythemia vera (PV); however, real-world data on its application across Philadelphia chromosome-negative (Ph-) myeloproliferative neoplasms (MPNs) remain limited. [PATIENTS AND METHODS] This retrospective coho...
Essential thrombocythemia; Interferon; Myelofibrosis; Polycythemia vera; Prefibrotic primary myelofibrosis
null
null
null
null
null
40,683,583
Epidemiology and molecular characterization of multidrug-resistant Mycobacterium tuberculosis among patients with pulmonary symptoms in Kaduna State, Nigeria.
Acta tropica
Acta Trop
269
null
10.1016/j.actatropica.2025.107748
eng
2,025
9
null
2,025
7
17
[BACKGROUND] The emergence and spread of multidrug-resistant tuberculosis (MDR-TB) is a critical-priority global health problem that requires molecular-based surveillance to understand its extent of transmission. [MATERIALS AND METHODS] Sputa from 360 patients with pulmonary symptoms were collected and processed for cu...
Isoniazid resistance; MDR-TB; Mycobacterium tuberculosis; Rifampicin resistance; rpoB genes
0.752
122
Insect Science; Veterinary; Infectious Diseases; Parasitology
Agricultural and Biological Sciences; Immunology and Microbiology; Medicine; Veterinary
2,024
40,683,392
Outcome of Debridement, Antibiotics, and Implant Retention for Treatment of Late Acute Hematogenous Periprosthetic Joint Infections.
The Journal of arthroplasty
J Arthroplasty
null
null
10.1016/j.arth.2025.07.008
eng
2,025
7
17
2,025
7
17
[BACKGROUND] Late acute hematogenous periprosthetic joint infections (LAHPJIs) pose a unique challenge to the arthroplasty surgeon. While debridement, antibiotics, and implant retention (DAIR) is a common method for treatment, success rates vary widely. Our study aimed to provide clarity on the efficacy of DAIR in trea...
debridement and implant retention; late acute hematogenous prosthetic joint infection; prosthetic joint infection; total hip arthroplasty; total knee arthroplasty
1.951
171
Orthopedics and Sports Medicine
Medicine
2,024
40,683,360
Satellitosis/in-transit metastasis in cutaneous squamous cell carcinoma: Risk factors and the prognostic significance.
Journal of the American Academy of Dermatology
J Am Acad Dermatol
null
null
10.1016/j.jaad.2025.07.029
eng
2,025
7
17
2,025
7
17
[BACKGROUND] Satellitosis or in-transit metastasis (S-ITM) from cutaneous squamous cell carcinoma (cSCC) is associated with poor outcomes but is not included in current staging guidelines. [OBJECTIVE] To determine risk factors and prognostic significance of S-ITM. [METHODS] This cohort study included 8,901 patients wit...
cutaneous squamous cell carcinoma; in-transit-metastases; outcomes; risk factors; satellitosis
1.315
256
Dermatology
Medicine
2,024
40,683,110
Longitudinal association between plasma epidermal growth factor and the progression of anxiety and depressive symptoms in Parkinson's disease.
Psychoneuroendocrinology
Psychoneuroendocrinology
180
null
10.1016/j.psyneuen.2025.107551
eng
2,025
7
14
2,025
7
14
[OBJECTIVE] Parkinson's disease (PD) is marked by a high incidence of neuropsychiatric symptoms that significantly impact the patients' quality of life. Biomarkers for monitoring anxiety and depressive symptoms in patients with PD are currently scarce. Epidermal growth factor (EGF), a neuroprotective growth factor, is ...
Anxiety; Depression; EGF; Parkinson's disease
1.454
210
Endocrine and Autonomic Systems; Endocrinology; Endocrinology, Diabetes and Metabolism; Psychiatry and Mental Health; Biological Psychiatry
Biochemistry, Genetics and Molecular Biology; Medicine; Neuroscience
2,024
40,683,093
Risk of anxiety disorders after epilepsy diagnosis: A nationwide retrospective cohort study.
Epilepsy & behavior : E&B
Epilepsy Behav
171
null
10.1016/j.yebeh.2025.110602
eng
2,025
7
18
2,025
7
18
[OBJECTIVE] To evaluate the long-term psychiatric consequences of an epilepsy diagnosis on the incidence of anxiety disorders among patients in South Korea. [METHOD] This study utilized data from the Korean National Health Insurance Service spanning 2002-2013 to analyze longitudinal risks and contributing factors for a...
Anxiety disorders; Cohort studies; Epilepsy; Risk factors; South Korea
null
null
null
null
null
40,683,078
Is it time to expand the surgical criteria? The psychosocial impact of pectus excavatum in pediatrics.
Surgery
Surgery
185
null
10.1016/j.surg.2025.109546
eng
2,025
7
18
2,025
7
18
[BACKGROUND] The physiologic sequelae of pectus excavatum are well known; however, the impact on body image remains understudied. We aimed to assess the psychosocial impact of pectus excavatum in children and congruency with their parents. [METHODS] The Pediatric Quality-of-Life Inventory 4.0, Severity Measure for Soci...
null
null
null
null
null
null
40,682,749
Unveiling the hidden risks: 90-day mortality and complications in older adults with proximal femur fractures.
Aging clinical and experimental research
Aging Clin Exp Res
37
1
10.1007/s40520-025-03134-0
eng
2,025
7
19
2,025
7
19
[BACKGROUND] Proximal femur fractures (PFF) are the most common fracture type worldwide, particularly in geriatric patients. Despite advancement in treatment, mortality rates in this patient group remain high. [AIMS] The aim of this study was to analyze potential factors, influencing the 90-day mortality rate and compl...
Geriatric; Mortality; Proximal femur fracture; Risk factors
1.144
95
Aging; Geriatrics and Gerontology
Biochemistry, Genetics and Molecular Biology; Medicine
2,024
40,682,491
Investigating the Consequences of Measurement Error of Gradually More Sophisticated Long-Term Personal Exposure Models in Assessing Health Effects: The London Study (MELONS).
Research report (Health Effects Institute)
Res Rep Health Eff Inst
2025
227
null
eng
2,025
5
null
null
null
null
[INTRODUCTION] Cohort studies have been widely used to estimate the effects of long-term exposure to air pollutants on health outcomes. The nature of the exposure (i.e., personal exposure to outdoor-generated pollution) and the large number of participants in cohorts preclude measuring individual exposure longitudinall...
null
null
null
null
null
null
40,682,254
Effect of 3-mercaptopyruvate sulfurtransferase (3-MST) inhibitors on contractile responses in porcine coronary artery.
British journal of pharmacology
Br J Pharmacol
null
null
10.1111/bph.70141
eng
2,025
7
18
2,025
7
18
[BACKGROUND AND PURPOSE] Hydrogen sulphide (H2S) is synthesised endogenously through cystathionine β-synthase (CBS), cystathionine γ-lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3-MST). Although exogenous H2S is known to produce vasodilatation, the vascular effect of H2S produced through 3-MST is unknown. In t...
coronary vessels; hydrogen sulphide; vasoconstriction
2.344
252
Pharmacology
Pharmacology, Toxicology and Pharmaceutics
2,024
40,681,978
The development and validation of the irrational beliefs scale for people living with HIV.
BMC public health
BMC Public Health
25
1
10.1186/s12889-025-23611-5
eng
2,025
7
18
2,025
7
18
[OBJECTIVE] To develop a culturally adapted scale measuring HIV-related irrational beliefs among PLHIV in China, and to examine its psychometric properties. [METHODS] The study was conducted from 05/2022 to 11/2023 with four stages. Stage 1: a pool of items was constructed through semi-structured interviews with 48 PLH...
Irrational beliefs; People living with HIV; Reliability and validity; Scale development
1.359
211
Public Health, Environmental and Occupational Health
Medicine
2,024
40,681,972
Innovative nitric oxide delivery technology for postoperative pulmonary hypertension in congenital heart disease patients: a clinical trial.
BMC cardiovascular disorders
BMC Cardiovasc Disord
25
1
10.1186/s12872-025-04967-3
eng
2,025
7
18
2,025
7
18
[BACKGROUND] Inhaled nitric oxide (iNO) is a selective pulmonary vasodilator with therapeutic benefits for pulmonary hypertension patients. Traditional cylinder-based iNO delivery systems are costly and complex, creating unmet medical needs. This study evaluated the safety and efficacy of a novel electrochemical nitric...
Congenital heart disease; Electrochemical nitric oxide generator; Pulmonary hypertension
0.708
76
Cardiology and Cardiovascular Medicine
Medicine
2,024
40,681,947
Surgical outcomes in diffuse leptomeningeal glioneuronal tumours: a systematic review and individual patient data meta-analysis.
Neurosurgical review
Neurosurg Rev
48
1
10.1007/s10143-025-03732-6
eng
2,025
7
19
2,025
7
19
[OBJECTIVE] Diffuse leptomeningeal glioneuronal (DLGNT) tumours are rare entities whose tumour characteristics and surgical outcomes have eluded clarification. We present the first survival analysis to date. [METHODS] A systematic search of the Medline, EMBASE, SCOPUS, Google Scholar and Cochrane Database of Systematic...
null
0.978
77
Medicine; Surgery; Neurology
Medicine
2,024
40,681,101
Precision Treatment of Cryptogenic Brain Abscesses: Metagenomic Next-generation Sequencing and Imaging for Recurrence Control.
World neurosurgery
World Neurosurg
201
null
10.1016/j.wneu.2025.124288
eng
2,025
7
16
2,025
7
16
[OBJECTIVE] To investigate the precision diagnosis and treatment strategies for cryptogenic brain abscesses, integrating multimodal imaging (320-slice computed tomography + 3.0 T magnetic resonance imaging) and metagenomic next-generation sequencing (mNGS) technology to optimize treatment regimens and control recurrenc...
Cryptogenic brain abscess; Metagenomic sequencing; Personalized therapy; Treatment efficacy
0.709
123
Neurology; Surgery
Medicine
2,024
40,680,947
Forced oscillatory technique R5-19 values correlate with spirometry FEV1/FVC in severe eosinophilic asthma. An observational, prospective, cohort study.
Respiratory medicine
Respir Med
247
null
10.1016/j.rmed.2025.108260
eng
2,025
7
16
2,025
7
16
[INTRODUCTION] Severe asthma affects 3-10 % of asthmatic patients. Biologic therapies can act as disease modifying agents in severe asthma. The prevalence of small airways dysfunction (SAD) increases with asthma severity. Forced Oscillatory Technique (FOT) is a reliable method for studying small airways. The aim of the...
Eosinophils; FOT; Oscillometry; R5-19; Severe asthma; Small airways disease
1.063
145
Pulmonary and Respiratory Medicine
Medicine
2,024
40,680,379
A bibliometric analysis of clear aligner therapy research articles published over 5 years - 2020-2024.
International orthodontics
Int Orthod
23
3
10.1016/j.ortho.2025.101039
eng
2,025
7
17
2,025
7
17
[OBJECTIVE] To identify and evaluate research articles regarding clear aligner therapy (CAT) published between 2020 and 2024 inclusive. [METHODS] A systematic strategy was employed to search the Web of Science Core Collection (Clarivate Analytics, Philadelphia, Pa) and the Incites Journal Citation Reports (Clarivate An...
Bibliometric study; Clear aligner therapy; Orthodontics; Research methodology
0.653
24
Orthodontics
Dentistry
2,024
40,680,235
Comparing the Performance of Machine Learning Models and Conventional Risk Scores for Predicting Major Adverse Cardiovascular Cerebrovascular Events After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction: Systematic Review and Meta-Analysis.
Journal of medical Internet research
J Med Internet Res
27
null
10.2196/76215
eng
2,025
7
18
2,025
7
18
[BACKGROUND] Machine learning (ML) models may offer greater clinical utility than conventional risk scores, such as the Thrombolysis in Myocardial Infarction (TIMI) and Global Registry of Acute Coronary Events (GRACE) risk scores. However, there is a lack of knowledge on whether ML or traditional models are better at p...
machine learning; mortality; myocardial infarction; patient readmission; percutaneous coronary intervention; prediction algorithm; statistical model
1.992
214
Health Informatics
Medicine
2,024
40,680,170
Spatiotemporal analysis of Crohn's disease reveals PECAM2 signaling at the basis of inflammation-to-fibrosis transition.
Journal of Crohn's & colitis
J Crohns Colitis
null
null
10.1093/ecco-jcc/jjaf130
eng
2,025
7
18
2,025
7
18
[BACKGROUND AND AIMS] Crohn's disease is a chronic inflammatory disease of the bowel, often complicated by fibrotic strictures, for which medical treatment is lacking, and surgery is commonly required. The mechanisms underlying the progression from chronic inflammation to fibrosis are not yet defined. We aim to unravel...
Chronic inflammation; fibrosis; spatial transcriptomics
null
null
null
null
null
40,680,169
Impact of Severe Skeletal Muscle Loss During the Waiting Period on Prognosis in Lung Transplantation for Interstitial Lung Disease.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Eur J Cardiothorac Surg
67
8
10.1093/ejcts/ezaf240
eng
2,025
8
2
null
null
null
[OBJECTIVES] This study aimed to evaluate the impact of skeletal muscle loss during the waiting period on postoperative outcomes following lung transplantation for interstitial lung disease. [METHODS] This retrospective analysis included adult patients with interstitial lung disease who underwent deceased- or living-do...
interstitial lung disease; lung transplantation; sarcopenia; skeletal muscle density; skeletal muscle mass
1.033
158
Cardiology and Cardiovascular Medicine; Medicine; Pulmonary and Respiratory Medicine; Surgery
Medicine
2,024
40,680,104
Unlocking the Treatment Code for Uveitis: The Potential Role of Epigenetics.
Current eye research
Curr Eye Res
null
null
10.1080/02713683.2025.2528245
eng
2,025
7
18
2,025
7
18
[PURPOSE] To systematically explore the multi-dimensional mechanisms of the epigenetic regulatory network in uveitis, address the challenges faced by traditional treatments, and provide new ideas and directions for the precise diagnosis and treatment of this disease. [METHODS] A systematic review was conducted on the e...
DNA methylation; Uveitis; epigenetics; histone modification; non-coding RNA
0.693
94
Ophthalmology; Cellular and Molecular Neuroscience; Sensory Systems
Medicine; Neuroscience
2,024
40,679,998
Effect of the TIM-3/Gal-9 signaling pathway on macrophage polarization in peri-implantitis.
PloS one
PLoS One
20
7
10.1371/journal.pone.0328258
eng
2,025
null
null
2,025
7
18
[INTRODUCTION] Peri-implantitis (PI) is a common complication of oral implant surgeries. Understanding the role of T-cell immunoglobulin and mucin domain-containing protein 3 (TIM-3) and its ligand galectin-9 (Gal-9) in PI is essential for advancing treatment strategies. This study investigated the effect of the TIM-3/...
null
0.803
467
Multidisciplinary
Multidisciplinary
2,024
40,679,788
circRNA_Atp8a1 Promotes Glycolytic Reprogramming in Damage of Intestinal Mucosal Barrier by Upregulating IGF2 through miR-200b-3p.
Tissue engineering and regenerative medicine
Tissue Eng Regen Med
null
null
10.1007/s13770-025-00737-6
eng
2,025
7
18
2,025
7
18
[BACKGROUND] This study investigated a circRNA (Circ_Atp8a1) in regulating intestinal epithelial repair in intestinal mucosal barrier damage. [METHODS] A mouse model of intestinal mucosal barrier damage caused by burn injury was constructed. Skin and intestinal histopathologic changes in injured and control mice were c...
Burn associated intestinal injury; Competing endogenous RNA; Glycolytic reprogramming; Intestinal barrier function; miR-200b-3p/IGF2 axis
0.978
43
Biomedical Engineering; Medicine
Engineering; Medicine
2,024
40,679,481
Parental perceptions and gender as predictors of changes in children's understanding of how to use a power wheelchair.
Disability and rehabilitation. Assistive technology
Disabil Rehabil Assist Technol
null
null
10.1080/17483107.2025.2533510
eng
2,025
7
18
2,025
7
18
[PURPOSE] To explore: (1) Whether parental perceptions predicted children's understanding of how to use a power wheelchair (PWC), as assessed via the Assessment of Learning Powered mobility use (ALP) across a study period, and (2) Relationships between child characteristics and ALP scores. [MATERIALS AND METHODS] Data ...
Power wheelchairs; cerebral palsy; gamified power mobility training; parental perceptions; pediatrics; power mobility; power wheelchair skills training
null
null
null
null
null
40,679,111
Association Between Cholesterol Remnants and Cardiac Structure and Function: The Copenhagen City Heart Study.
Echocardiography (Mount Kisco, N.Y.)
Echocardiography
42
7
10.1111/echo.70249
eng
2,025
7
null
null
null
null
[AIMS] A causal relationship between ischemic heart disease and cholesterol remnants (CR) has been suggested by genetic studies. We studied whether CR are associated with alterations in cardiac structure and function, as evaluated by sensitive echocardiographic measures in individuals without known heart disease. [METH...
cholesterol remnants; echocardiography; epidemiology; lipids
0.353
74
Cardiology and Cardiovascular Medicine; Medicine; Radiology, Nuclear Medicine and Imaging
Medicine
2,024
40,678,785
Incidentally Diagnosed Asymptomatic COVID-19 Does Not Increase Total Complication Risk in Total Joint Arthroplasty.
Arthroplasty today
Arthroplast Today
34
null
10.1016/j.artd.2025.101745
eng
2,025
8
null
2,025
7
2
[BACKGROUND] Impacts of asymptomatic perioperative coronavirus disease 2019 (COVID-19) on total knee (TKA) and hip arthroplasty (THA) outcomes remains unknown. [METHODS] We retrospectively reviewed asymptomatically screened COVID-19 cases undergoing primary TKA or THA between 2020 and 2022. Ninety-day complications, in...
Coronavirus; Joint replacement; Postoperative complications; Preoperative screening; SARS-CoV-2; Silent infection
0.918
32
Orthopedics and Sports Medicine; Surgery
Medicine
2,024
40,678,778
Association between non-high-density lipoprotein cholesterol-to-high-density lipoprotein cholesterol ratio and the risk of gestational diabetes: a retrospective study.
Frontiers in nutrition
Front Nutr
12
null
10.3389/fnut.2025.1617225
eng
2,025
null
null
2,025
7
3
[BACKGROUND] Previous studies have shown an association between non-high-density lipoprotein cholesterol (non-HDL-C)-to-HDL-C ratio (NHHR) and diabetes; however, its impact on pregnant women remains unclear. This study aims to explore the association between NHHR in early to mid-pregnancy and the incidence of gestation...
RCS curve; ROC curve; association; gestational diabetes mellitus; non-HDL-to-HDL cholesterol ratio
1.115
94
Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism
Agricultural and Biological Sciences; Medicine; Nursing
2,024
40,678,634
Physician professional motivation and online knowledge sharing for patient education: a perspective of motivation theory.
Frontiers in public health
Front Public Health
13
null
10.3389/fpubh.2025.1629272
eng
2,025
null
null
2,025
7
3
[AIMS] Drawing on motivation theory, this study aims to investigate the effect of professional motivation on online knowledge sharing for patient education with considering the contingencies of online experience and offline expertise. [METHODS] Based on a panel dataset comprising 11,839 physicians with 24,389 physician...
offline expertise; online experience; online knowledge sharing; patient education; professional motivation
1.027
119
Public Health, Environmental and Occupational Health
Medicine
2,024
40,678,397
Dosimetric evaluation of cone beam computed tomography-guided online adaptive radiotherapy in gastric mucosa-associated lymphoid tissue lymphoma.
Technical innovations & patient support in radiation oncology
Tech Innov Patient Support Radiat Oncol
35
null
10.1016/j.tipsro.2025.100321
eng
2,025
9
null
2,025
6
25
[INTRODUCTION] This study evaluated dosimetric values of cone beam computed tomography (CBCT)-guided online adaptive radiotherapy (oART) in patients with gastric mucosa-associated lymphoid tissue (MALT) lymphoma, accounting for interfractional and intrafractional motion. [METHODS] Four patients with stage I gastric MAL...
CBCT; Gastric MALT; Intrafractional motion; Online adaptive radiotherapy
null
null
null
null
null
40,678,085
Effect of orbitotomy on surgical freedom in Endoscopic Transorbital Approach (ETOA) to the skull base: An anatomical study.
Brain & spine
Brain Spine
5
null
10.1016/j.bas.2025.104300
eng
2,025
null
null
2,025
6
18
[INTRODUCTION] To investigate the angle of attacks and surgical freedom in different extents of orbitotomy for Endoscopic Transorbital Approach to the skull base. [BACKGROUND] Endoscopic Transorbital Approach is gaining popularity among skull base surgeons over the last decade.The surgery can be performed with or witho...
Endoscopic transorbital surgery; Orbitotomy; Surgical freedom
null
null
null
null
null