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40,678,050 | Glutamine potentiates cefoperazone-sulbactam activity against Pseudomonas aeruginosa by increasing membrane permeability and cellular uptake. | Frontiers in microbiology | Front Microbiol | 16 | null | 10.3389/fmicb.2025.1631646 | eng | 2,025 | null | null | 2,025 | 7 | 3 | [PURPOSES] The combination of an antibiotic with a metabolic reprogramming agent is anticipated to emerge as a promising therapeutic strategy against antibiotic-resistant bacteria, though this hypothesis requires validation through preclinical pharmacodynamic studies. [METHODS] This study evaluated the preclinical phar... | Pseudomonas aeruginosa; carbapenem resistance; cefoperazone/sulbactam; glutamine; multidrug resistance; preclinical pharmacodynamics | 1.172 | 259 | Microbiology; Microbiology | Immunology and Microbiology; Medicine | 2,024 |
40,678,026 | Levels of osteocalcin and N-terminal telopeptide of type I collagen in men with ankylosing spondylitis: associations with disease course and structural-functional status of bone tissue. | Reumatologia | Reumatologia | 63 | 3 | 10.5114/reum/201175 | eng | 2,025 | null | null | 2,025 | 6 | 20 | [INTRODUCTION] The aim was to assess osteocalcin (OC) and N-terminal telopeptide of type I collagen (NTx) levels in men with ankylosing spondylitis (AS) and evaluate their relationship with the course of the disease and the structural and functional state of bone tissue. [MATERIAL AND METHODS] The study was conducted o... | BMD; ankylosing spondylitis; markers of bone tissue; osteocalcin | 0.5 | 30 | Immunology; Immunology and Allergy; Rheumatology | Immunology and Microbiology; Medicine | 2,024 |
40,677,899 | The Effect of Mild Residual Rotational Laxity on Performance After Anterior Cruciate Ligament Reconstruction. | Orthopaedic journal of sports medicine | Orthop J Sports Med | 13 | 7 | 10.1177/23259671251352205 | eng | 2,025 | 7 | null | 2,025 | 7 | 16 | [BACKGROUND] Some patients still experience mild residual rotational laxity of the knee after anterior cruciate ligament reconstruction (ACLR). The clinical symptoms of this residual rotational laxity are controversial, and methods for evaluating the symptoms have become a focus of academic interest in recent years. It... | anterior cruciate ligament; psychological readiness; return to sports; rotational mild instability | 1.258 | 68 | Orthopedics and Sports Medicine | Medicine | 2,024 |
40,677,800 | A Long-Term Follow-Up of 2 Cases of Subclinical Acromegaly. | AACE endocrinology and diabetes | AACE Endocrinol Diabetes | 12 | 1 | 10.1016/j.aed.2025.02.003 | eng | 2,025 | null | null | 2,025 | 4 | 10 | [BACKGROUND/OBJECTIVE] Atypical presentations of acromegaly are rare. We present long-term follow-up of 2 patients with acromegaly who had nonspecific symptoms with elevated growth hormone (GH) and insulin-like growth factor-1 (IGF-1) levels but lacked classical clinical features. [CASE REPORT] The first case was a 34-... | pituitary macroadenoma; silent acromegaly; silent somatotropinoma; subclinical acromegaly | null | null | null | null | null |
40,677,794 | Successful Treatment of Hypothalamic Obesity with Tirzepatide. | AACE endocrinology and diabetes | AACE Endocrinol Diabetes | 12 | 1 | 10.1016/j.aed.2025.03.004 | eng | 2,025 | null | null | 2,025 | 4 | 10 | [BACKGROUND/OBJECTIVE] Hypothalamic obesity (HO) is a rare but severe form of obesity characterized by hypothalamic damage resulting in hyperphagia and decreased energy expenditure. Tumors involving the hypothalamus, most commonly craniopharyngiomas, frequently result in HO. Treatment is typically refractory to standar... | antiobesity medication; hypothalamic; hypothalamic obesity; obesity; tirzepatide | null | null | null | null | null |
40,677,718 | Serum GDF15 level as predictive biomarker of clinical outcome in patients with unresectable hepatocellular carcinoma treated with hepatic arterial infusion chemotherapy. | Frontiers in immunology | Front Immunol | 16 | null | 10.3389/fimmu.2025.1619387 | eng | 2,025 | null | null | 2,025 | 7 | 3 | [BACKGROUND] Hepatic arterial infusion chemotherapy (HAIC) using the FOLFOX regimen has been explored for unresectable hepatocellular carcinoma (HCC) patients, yet predictive biomarkers are lacking. This study aimed to evaluate the potential of serum growth differentiation factor 15 (GDF15) as a biomarker for predictin... | growth differentiation factor 15; hepatic arterial infusion chemotherapy; hepatocellular carcinoma; overall survival; progression-free survival; serum biomarker | 1.941 | 259 | Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,024 |
40,677,597 | Academically based regional quality improvement hubs: Advancing Medicaid's quality strategy in the state of Ohio through state-academic partnerships. | Learning health systems | Learn Health Syst | 9 | 3 | 10.1002/lrh2.10480 | eng | 2,025 | 7 | null | 2,025 | 1 | 7 | [INTRODUCTION] In 2022, the Ohio Department of Medicaid (ODM) launched a Managed Care Population Health and Quality Strategy to improve healthcare quality and equity for Medicaid Managed Care enrollees. Aligned with national quality objectives, the strategy focuses on personalized care, service coordination for complex... | Medicaid quality strategy; quality improvement hub | null | null | null | null | null |
40,677,575 | Refractory chronic diarrhea complicated with optic neuritis in a young woman: A case report. | World journal of gastrointestinal endoscopy | World J Gastrointest Endosc | 17 | 7 | 10.4253/wjge.v17.i7.106208 | eng | 2,025 | 7 | 16 | null | null | null | [BACKGROUND] Collagenous sprue is a serious intestinal malabsorption disorder characterized by dull and flattened intestinal villi with subepithelial collagen deposition. At present, fewer than 100 cases have been reported in the literature. Owing to the rarity of this disease, clinicians and pathologists have insuffic... | Case report; Chronic diarrhea; Collagenous sprue; Glucocorticoid dependence; Malabsorption; Optic neuritis | null | null | null | null | null |
40,677,286 | Value of single-center fecal calprotectin in the early diagnosis and assessment of necrotizing enterocolitis in premature infants. | Frontiers in pediatrics | Front Pediatr | 13 | null | 10.3389/fped.2025.1598448 | eng | 2,025 | null | null | 2,025 | 7 | 3 | [OBJECTIVE] To explore the value of fecal calprotectin (FC) in the early diagnosis of necrotizing enterocolitis (NEC) in premature infants. [METHODS] From September 2021 to June 2024, 84 premature infants with NEC were selected as the NEC group, and 84 premature infants with feeding intolerance (feeding intolerance gro... | assessment; disease assessment; early diagnosis; fecal calprotectin; necrotizing enterocolitis; premature infants | 0.738 | 83 | Pediatrics, Perinatology and Child Health | Medicine | 2,024 |
40,677,239 | Improving T2D machine learning-based prediction accuracy with SNPs and younger age. | Computational and structural biotechnology journal | Comput Struct Biotechnol J | 27 | null | 10.1016/j.csbj.2025.06.038 | eng | 2,025 | null | null | 2,025 | 6 | 23 | [BACKGROUND] This study aimed to evaluate whether integrating clinical and genomic data improves the performance of machine learning (ML) models for predicting Type 2 Diabetes (T2D) risk. [METHODS] Six models-Random Forest, Support Vector Machine, Linear Discriminant Analysis, Logistic Regression, Gradient Boosting Mac... | AI; Machine Learning; Predictive models; T2D | 1.561 | 92 | Biochemistry; Biophysics; Biotechnology; Computer Science Applications; Genetics; Structural Biology | Biochemistry, Genetics and Molecular Biology; Computer Science | 2,024 |
40,677,127 | Self-Management and Affecting Factors in Dialysis Patients Experiencing the Earthquake in Türkiye. | Disaster medicine and public health preparedness | Disaster Med Public Health Prep | 19 | null | 10.1017/dmp.2025.10103 | eng | 2,025 | 7 | 18 | 2,025 | 7 | 18 | [OBJECTIVES] The present study was conducted to determine self-management and influencing factors in dialysis patients who experienced the earthquake. [METHODS] The study was conducted descriptively with 125 patients receiving dialysis in a city affected by the earthquake in Türkiye. Data were collected with the "Perso... | Dialysis; Earthquake; Hemodialysis; Nursing; Self-Management; Survival; Vulnerable Populations | 0.555 | 60 | Public Health, Environmental and Occupational Health | Medicine | 2,024 |
40,677,010 | PRMT5:MEP50 Are Mediators of Treatment-Induced Neuroendocrine Differentiation in Prostate Cancer. | The Prostate | Prostate | 85 | 13 | 10.1002/pros.70006 | eng | 2,025 | 9 | null | 2,025 | 7 | 17 | [BACKGROUND] Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer responsible for an estimated 20%-30% of castration-resistant prostate cancer (CRPC) deaths. While NEPC can arise spontaneously, the majority of these cases emerge as treatment-induced NEPC (tNEPC). Our clinical and computational a... | PRMT5; drug resistance; enzalutamide; neuroendocrine | 1.071 | 138 | Urology; Oncology | Medicine | 2,024 |
40,676,927 | Barriers and Facilitators for Accessing Oral Health Care for Ukrainian Newcomers to Nova Scotia. | JDR clinical and translational research | JDR Clin Trans Res | null | null | 10.1177/23800844251352395 | eng | 2,025 | 7 | 17 | 2,025 | 7 | 17 | [INTRODUCTION] The war in Ukraine has resulted in a mass exodus of Ukrainians fleeing their country and seeking resettlement in many countries, including Canada. There is a lack of literature, particularly qualitative, that explores past experiences with oral health care in the country of origin for newcomers and the e... | Acculturation; Canada; Health insurance; Health knowledge; Language; Refugees | 0.906 | 29 | Dentistry | Dentistry | 2,024 |
40,676,668 | Quantitative computed tomography analysis of bone microarchitecture is associated with rotator cuff healing. | Journal of orthopaedic surgery and research | J Orthop Surg Res | 20 | 1 | 10.1186/s13018-025-06102-6 | eng | 2,025 | 7 | 17 | 2,025 | 7 | 17 | [BACKGROUND] Rotator cuff repair in patients with osteoporosis (OP) is often hindered by poor tendon-to-bone healing and a high rate of retears, largely due to compromised bone remodeling at the repair site. However, few studies have investigated the relationship between computed tomography (CT)-based quantitative anal... | Bone microarchitecture; Osteoporosis; Quantitative computed tomography; Rotator cuff tear | 0.877 | 75 | Orthopedics and Sports Medicine; Surgery | Medicine | 2,024 |
40,676,516 | Co-occurrence of Peutz-Jeghers syndrome and unilateral multicystic dysplastic kidney: a case report. | BMC nephrology | BMC Nephrol | 26 | 1 | 10.1186/s12882-025-04340-8 | eng | 2,025 | 7 | 17 | 2,025 | 7 | 17 | [BACKGROUND] This case study aimed to evaluate the co-occurrence of Peutz-Jeghers syndrome (PJS) and unilateral multicystic dysplastic kidney (MCDK) disease through clinical and genetic analysis of a patient with both conditions. [CASE PRESENTATION] A 13-year-and-7-month-old female patient presented with typical featur... | LKB1; STK11; Case report; Multicystic dysplastic kidney; Peutz-Jeghers syndrome | 0.805 | 83 | Nephrology | Medicine | 2,024 |
40,675,884 | The Impact of Functional Status Assessed by the Barthel Index on Postoperative Outcomes in Patients Undergoing Cardiac Surgery: A Retrospective Cohort Study. | Journal of cardiothoracic and vascular anesthesia | J Cardiothorac Vasc Anesth | null | null | 10.1053/j.jvca.2025.06.044 | eng | 2,025 | 6 | 27 | 2,025 | 6 | 27 | [OBJECTIVES] To examine the impact of functional status assessed using the Barthel Index (BI) on acute kidney injury (AKI), intensive care unit (ICU) and hospital length of stay, and in-hospital mortality in patients undergoing cardiac surgery. [DESIGN] A retrospective cohort study. [SETTING] An academic hospital in Ch... | Barthel Index; acute kidney injury; cardiac surgery; mortality | 0.68 | 100 | Anesthesiology and Pain Medicine; Cardiology and Cardiovascular Medicine | Medicine | 2,024 |
40,675,550 | The diabetes gene Tcf7l2 organizes gene expression in the liver and regulates amino acid metabolism. | Molecular metabolism | Mol Metab | 99 | null | 10.1016/j.molmet.2025.102208 | eng | 2,025 | 9 | null | 2,025 | 7 | 15 | [OBJECTIVE] Though Tcf7l2 harbors the strongest genetic association with diabetes identified thus far, how it promotes metabolic disease remains unclear. Our aim was to dissect the contribution of hepatic TCF7L2. [METHODS] Mice with liver-specific knockout of Tcf7l2 produced by targeted deletion of exon 1 were subjecte... | Diabetes; Metabolism; Transcription; Zonation | 3.235 | 115 | Cell Biology; Molecular Biology | Biochemistry, Genetics and Molecular Biology | 2,024 |
40,675,517 | Identification Of ANGPT2, FLT3, IGF1, and SPP1 associated with glycolysis and PI3K/Akt signaling pathway in hepatocellular carcinoma. | Gene | Gene | 966 | null | 10.1016/j.gene.2025.149644 | eng | 2,025 | 7 | 15 | 2,025 | 7 | 15 | [BACKGROUND] Hepatocellular carcinoma (HCC) is a malignant hepatic neoplasm characterized by rapid cellular proliferation facilitated by aerobic glycolysis. Additionally, the PI3K/Akt pathway enhances angiogenesis, thereby promoting the growth of HCC cells. This study aimed to identify biomarkers associated with glycol... | Bioinformatics; Biomarkers; Glycolysis; Hepatocellular carcinoma; PI3K-Akt signaling pathway | 0.682 | 200 | Medicine; Genetics | Biochemistry, Genetics and Molecular Biology; Medicine | 2,024 |
40,675,254 | Probing impact of sleep deprivation on hippocampal neurochemistry in rats using CEST imaging and [1]H-MRS at 7.0T MRI. | Neurochemistry international | Neurochem Int | 189 | null | 10.1016/j.neuint.2025.106020 | eng | 2,025 | 7 | 15 | 2,025 | 7 | 15 | [PURPOSE] Sleep is a physiological process that plays a crucial role in maintaining cognitive functions. The hippocampus, a key brain region implicated in cognition, is particularly sensitive to sleep deprivation. we aim to investigate impact of sleep deprivation on hippocampal neurochemistry in rats using CEST imaging... | Chemical Exchange Saturation Transfer (CEST); Hippocampus; Neurochemistry; Proton magnetic resonance spectroscopy ((1)H-MRS); Sleep deprivation | 1.193 | 141 | Cell Biology; Cellular and Molecular Neuroscience | Biochemistry, Genetics and Molecular Biology; Neuroscience | 2,024 |
40,674,950 | Brain metabolic and behavioral alterations in a Down syndrome model. | Nuclear medicine and biology | Nucl Med Biol | 148-149 | null | 10.1016/j.nucmedbio.2025.109052 | eng | 2,025 | 7 | 15 | 2,025 | 7 | 15 | [PURPOSE] This work aimed to monitor the Down Syndrome Ts65Dn animal model across lifespan to detect time-dependent in vivo molecular alterations that may be associated with neurodegeneration and neuroinflammation in this model. [METHODS] Euploid and trisomic Ts65Dn animals were longitudinally evaluated at 2, 5, 14, 20... | Brain connectivity; Down syndrome; Glucose metabolism; Neuroinflammation; Ts65Dn; [(18)F]FDG PET | 0.742 | 100 | Radiology, Nuclear Medicine and Imaging; Cancer Research; Molecular Medicine | Biochemistry, Genetics and Molecular Biology; Medicine | 2,024 |
40,674,864 | Characterizing intersystem and community values to enhance opioid use disorder treatments: Communities That Heal intervention in New York. | The International journal on drug policy | Int J Drug Policy | 143 | null | 10.1016/j.drugpo.2025.104922 | eng | 2,025 | 9 | null | 2,025 | 7 | 17 | [BACKGROUND] In response to rising overdose deaths, the State of New York established multisystem coalitions in 16 counties to tackle the opioid crisis. These coalitions brought together stakeholders from various systems, including healthcare, behavioral health, criminal justice, and community-based services to address... | Community coalition; Community-based intervention; Intersystem and community values; Medications for opioid use disorder; Naloxone; Opioid use disorder; Overdose | null | null | null | null | null |
40,674,763 | Disruptive behaviors in early childhood: the influence of family practices and functionality in a Turkish sample. | The Turkish journal of pediatrics | Turk J Pediatr | 67 | 3 | 10.24953/turkjpediatr.2025.5782 | eng | 2,025 | 7 | 8 | 2,025 | 7 | 8 | [BACKGROUND] Disruptive behaviors (DB) are common problems in young children. The aim of the current study was to highlight the effect of disruptive behaviors on functionality in preschool children and their families and identify factors that may be related to functionality. [MATERIALS AND METHODS] A total of 223 patie... | children; disruptive behaviors; functionality; parenting; preschool | 0.304 | 41 | Pediatrics, Perinatology and Child Health | Medicine | 2,024 |
40,674,663 | Implementation of Quality Improvement Interventions in Medical Oncology: A Systematic Review. | JCO oncology practice | JCO Oncol Pract | null | null | 10.1200/OP-25-00289 | eng | 2,025 | 7 | 17 | 2,025 | 7 | 17 | [PURPOSE] As global cancer rates rise, the demand for effective, high-quality delivery of systemic anticancer therapy (SACT) is crucial. However, quality improvement (QI) research in medical oncology remains limited. This systematic review aims to identify and characterize QI interventions addressing quality deficits i... | null | 2.346 | 85 | Health Policy; Oncology; Oncology | Medicine; Nursing | 2,024 |
40,673,923 | pH-responsive chitosan-alginate hydrogel beads: for enhanced bioavailability and controlled release of omeprazole. | Drug development and industrial pharmacy | Drug Dev Ind Pharm | null | null | 10.1080/03639045.2025.2536620 | eng | 2,025 | 7 | 22 | 2,025 | 7 | 22 | [OBJECTIVE] To develop a pH-responsive drug delivery using chitosan-alginate hydrogel beads for enhanced therapeutic efficacy of omeprazole. [SIGNIFICANCE] The developed system offers improved drug entrapment, release profiles, and enhanced bioavailability for omeprazole compared to commercial formulation. [METHODS] pH... | Omeprazole; hydrogel; pH-responsive; protection; sustained release | 0.451 | 106 | Pharmaceutical Science; Drug Discovery; Organic Chemistry; Pharmacology | Chemistry; Pharmacology, Toxicology and Pharmaceutics | 2,024 |
40,673,861 | Donidalorsen Treatment of Hereditary Angioedema in Patients Previously on Long-Term Prophylaxis. | The journal of allergy and clinical immunology. In practice | J Allergy Clin Immunol Pract | null | null | 10.1016/j.jaip.2025.06.018 | eng | 2,025 | 7 | 17 | 2,025 | 7 | 17 | [BACKGROUND] Hereditary angioedema (HAE) is a rare, potentially life-threatening disorder characterized by episodes of tissue swelling. Donidalorsen, an investigational ligand-conjugated antisense oligonucleotide, reduces plasma prekallikrein production. [OBJECTIVE] We report an interim analysis on safety, efficacy, qu... | Disease control; Donidalorsen; Hereditary angioedema; Open-label; Phase 3; Treatment preference | null | null | null | null | null |
40,673,511 | Comparative Risk of Atrial Fibrillation Onset in Statin-Treated Patients Initiating Icosapent Ethyl and Omega-3 Acid Ethyl Esters: A Retrospective Cohort Study. | Journal of the American Heart Association | J Am Heart Assoc | 14 | 15 | 10.1161/JAHA.124.038846 | eng | 2,025 | 8 | 5 | 2,025 | 7 | 17 | [BACKGROUND] Icosapent ethyl (IPE) and omega-3-acid ethyl esters (docosahexaenoic acid [DHA]/eicosapentaenoic acid [EPA]) are approved as adjunct therapies to statins for reducing cardiovascular events in at-risk patients. However, concerns remain regarding a potential link between IPE and atrial fibrillation (AF). We ... | atrial fibrillation; icosapent ethyl; retrospective cohort study | 2.189 | 152 | Cardiology and Cardiovascular Medicine | Medicine | 2,024 |
40,673,365 | Forest bathing improves inflammatory markers, SpO2, and subjective symptoms related to chronic obstructive pulmonary disease (COPD) in male subjects at risk of developing COPD. | Journal of occupational health | J Occup Health | 67 | 1 | 10.1093/joccuh/uiaf041 | eng | 2,025 | 1 | 7 | null | null | null | [BACKGROUND] Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide, responsible for 3.5 million deaths in 2021. Effective preventive measures are needed. Forest bathing has been reported to have positive effects on the immune system. In addition, the clean air, mild climate, phyton... | C-reactive protein; COPD; CRP; IL-6; chronic obstructive pulmonary disease; fibrinogen; forest bathing; interleukin 6 | 0.957 | 73 | Public Health, Environmental and Occupational Health | Medicine | 2,024 |
40,673,113 | Projecting lyme disease risk in the United States: A machine learning approach integrating environmental, socioeconomic and vector factors. | One health (Amsterdam, Netherlands) | One Health | 21 | null | 10.1016/j.onehlt.2025.101111 | eng | 2,025 | 12 | null | 2,025 | 6 | 13 | [OBJECTIVE] Lyme disease, caused by Borrelia burgdorferi and transmitted by blacklegged ticks (Ixodes species), is the most common vector-borne disease in the United States. Its spatiotemporal dynamics are influenced by environmental and socioeconomic factors, yet the impacts of the COVID-19 pandemic on Lyme disease re... | Blacklegged ticks; COVID-19 pandemic; Lyme disease; Machine learning | 1.202 | 43 | Infectious Diseases; Public Health, Environmental and Occupational Health | Medicine | 2,024 |
40,672,718 | Rapid On-Site Cytologic Evaluation-Facilitated Diagnosis of Fibrin-Associated Large B-Cell Lymphoma in a Right Atrial Fibrin Thrombus: A Case Report. | Case reports in oncology | Case Rep Oncol | 18 | 1 | 10.1159/000546869 | eng | 2,025 | null | null | 2,025 | 6 | 13 | [BACKGROUND] Fibrin-associated large B-cell lymphoma (FA-LBCL) is a rare extranodal lymphoma confined to fibrin deposits within cardiovascular structures and other anatomically restricted spaces. Due to its non-mass-forming nature and nonspecific clinical presentation, preoperative diagnosis remains challenging. [CASE ... | Cardiac lymphoma; Case report; Epstein-Barr virus; Fibrin-associated large B-cell lymphoma; Rapid on-site evaluation | 0.281 | 28 | Oncology | Medicine | 2,024 |
40,672,125 | Acceptability of a Microbiome-Directed Food for the Management of Children with Uncomplicated Acute Malnutrition in Maradi, Niger: Two Randomized Crossover Trials. | Current developments in nutrition | Curr Dev Nutr | 9 | 7 | 10.1016/j.cdnut.2025.107484 | eng | 2,025 | 7 | null | 2,025 | 6 | 9 | [BACKGROUND] A novel ready-to-use microbiome-directed food (MDF) has been developed for the management of acute malnutrition using ingredients that promote repair of the gut microbiota of undernourished children. [OBJECTIVES] This study aims to assess the acceptability of MDF compared with standard nutritional care amo... | Niger; acceptability; acute malnutrition; community-based management of acute malnutrition; microbiome-directed food | 0.737 | 41 | Food Science; Medicine; Nutrition and Dietetics | Agricultural and Biological Sciences; Medicine; Nursing | 2,024 |
40,671,913 | Augmentation of bone formation by sympathectomy in rats as evaluated by [[99m]Tc]Tc-MDP. | Frontiers in endocrinology | Front Endocrinol (Lausanne) | 16 | null | 10.3389/fendo.2025.1580230 | eng | 2,025 | null | null | 2,025 | 7 | 2 | [BACKGROUND] The role of the sympathetic nervous system in bone metabolism remains unclear. Given that [99m]Tc-methylene diphosphonate ([[99m]Tc]Tc-MDP) uptake reflects active bone formation and mineralization, this study aims to investigate the effects of sympathetic denervation on bone formation in rats using [[99m]T... | SPECT/CT imaging; [99m Tc]Tc-MDP; bone formation; rats; sympathectomy | 1.472 | 138 | Endocrinology, Diabetes and Metabolism | Medicine | 2,024 |
40,671,790 | Differential susceptibility to colonic ulceration in mice with genetic deletion of Prostaglandin E synthase. | Research square | Res Sq | null | null | 10.21203/rs.3.rs-6977322/v1 | eng | 2,025 | 7 | 7 | 2,025 | 7 | 7 | [BACKGROUND] Prostaglandin E2 (PGE2) exerts pleiotropic and context-dependent effects on inflammation, cancer and maintenance of intestinal mucosal homeostasis. To further define its role in intestinal diseases, we genetically inactivated its rate-limiting synthesis, Ptges, in two mouse lines. An unexpected phenotype c... | PGE2; colonic ulceration; gut microbiome; inflammatory bowel disease (IBD); mPGES-1; mouse models; non-steroidal anti-inflammatory drugs (NSAIDs) | null | null | null | null | null |
40,671,549 | Mapping disparities: identifying cancer care gaps in sexual and gender minority patients. | Journal of the National Cancer Institute. Monographs | J Natl Cancer Inst Monogr | 2025 | 69 | 10.1093/jncimonographs/lgaf030 | eng | 2,025 | 7 | 1 | null | null | null | [BACKGROUND] Sexual and gender minority (SGM) patients face disparities in cancer care, partly due to the lack of sexual orientation and gender identity (SOGI) data collection. We sought to use electronic health record-based metrics, integrated with SOGI data to characterize the SGM cancer population with the future go... | null | null | null | null | null | null |
40,671,313 | Potential Impact of Parental Origin of Inheritance on the Clinical Presentation of Familial Partial Lipodystrophy Type 2 Syndrome. | Clinical endocrinology | Clin Endocrinol (Oxf) | null | null | 10.1111/cen.15303 | eng | 2,025 | 7 | 16 | 2,025 | 7 | 16 | [CONTEXT] Familial partial lipodystrophy type 2 (FPLD2) is a rare autosomal dominant disorder caused by pathogenic variants in the LMNA gene. The influence of parental inheritance on clinical presentation has not been fully explored. [OBJECTIVE] To investigate the influence of maternal versus paternal inheritance of LM... | LMNA; body composition; fat mass; lean mass; partial lipodystrophy | 1.006 | 169 | Endocrinology; Endocrinology, Diabetes and Metabolism | Biochemistry, Genetics and Molecular Biology; Medicine | 2,024 |
40,671,191 | Criminal Trajectories Across the Dementia Timeline-A Nationwide Finnish Register Study. | International journal of geriatric psychiatry | Int J Geriatr Psychiatry | 40 | 7 | 10.1002/gps.70131 | eng | 2,025 | 7 | null | null | null | null | [OBJECTIVES] The aim of this longitudinal register study was to examine the crime counts, crime incidence and timing of criminal activity in relation to the diagnosis of Alzheimer's disease (AD), frontotemporal dementia (FTD) and Lewy body dementias (LBD). The objective was to analyse the associated risk factors and ri... | criminal behaviour; criminality; dementia; neurocognitive disorders; neuropsychiatric symptoms; older population | 1.221 | 157 | Geriatrics and Gerontology; Psychiatry and Mental Health | Medicine | 2,024 |
40,671,082 | Correlations between insertional Achilles tendinopathy and haglund's deformity: MRI and radiographic findings. | Journal of orthopaedic surgery and research | J Orthop Surg Res | 20 | 1 | 10.1186/s13018-025-06036-z | eng | 2,025 | 7 | 16 | 2,025 | 7 | 16 | [BACKGROUND] The relationship between insertional Achilles tendinopathy (IAT) and Haglund's deformity has not been fully elucidated. This study aimed to determine the optimal cutoff value of MRI-based Achilles thickness and intratendinous degeneration for IAT and further explored the correlations of IAT and Haglund's d... | Achilles tendon; Heel pain; Insertional achilles tendinopathy | 0.877 | 75 | Orthopedics and Sports Medicine; Surgery | Medicine | 2,024 |
40,670,953 | Exploring the link between screen time and severity of early childhood caries in primary molars: a cross-sectional study. | BMC oral health | BMC Oral Health | 25 | 1 | 10.1186/s12903-025-06135-7 | eng | 2,025 | 7 | 16 | 2,025 | 7 | 16 | [BACKGROUND] Early Childhood Caries (ECC) is a significant yet often overlooked paediatric health concern, particularly in India. Previous studies have linked excessive screen exposure, known as Problematic Screen Exposure (PSE), with caries in children. However, the association between PSE and the severity of ECC in t... | null | 0.843 | 80 | Dentistry | Dentistry | 2,024 |
40,670,062 | Migraine management in Saudi Arabia: An expert consensus. | Neurosciences (Riyadh, Saudi Arabia) | Neurosciences (Riyadh) | 30 | 3 | 10.17712/nsj.2025.3.20240118 | eng | 2,025 | 7 | null | null | null | null | [OBJECTIVE] To establish expert consensus on the preventive treatment of migraine in Saudi Arabia, with a focus on the use of calcitonin gene-related peptide monoclonal antibodies (CGRP mAbs), in light of the latest international guidelines and local clinical practice. [METHOD] A record-based study was performed retros... | null | null | null | null | null | null |
40,669,703 | Suicidal thoughts and behaviors in adolescents with mood disorders: Insights from a nationally representative sample. | Journal of affective disorders | J Affect Disord | 391 | null | 10.1016/j.jad.2025.119882 | eng | 2,025 | 7 | 14 | 2,025 | 7 | 14 | [BACKGROUND] Suicide is a leading cause of death in adolescents, and major mood disorders confer a greatly increased risk. Few population-based studies have investigated the distinct and overlapping clinical correlates of suicidality in adolescents with bipolar disorder (BD) and major depressive disorder (MDD). Underst... | Adolescents; Bipolar disorder; Major depressive disorder; Suicide | 2.121 | 245 | Clinical Psychology; Psychiatry and Mental Health | Medicine; Psychology | 2,024 |
40,669,324 | Do behavioral mother-infant sleep interventions in the first six months affect maternal sleep, anxiety, and fatigue? A randomized controlled trial. | Sleep medicine | Sleep Med | 134 | null | 10.1016/j.sleep.2025.106675 | eng | 2,025 | 7 | 10 | 2,025 | 7 | 10 | [BACKGROUND] Sleep problems, fatigue, and mental health challenges are common among mothers due to infants' frequent nighttime wakings. This study examined the impact of the mother-infant behavioral sleep interventions (BSIs) on maternal sleep/health (primary) and infant sleep (secondary) in mothers of infants under si... | Culture; Infant sleep; Iran; Maternal sleep; Sleep hygiene; Tiredness and anxiety | 1.231 | 159 | Medicine | Medicine | 2,024 |
40,669,267 | Barriers and facilitators to the implementation of a midwifery-led care model: a qualitative systematic review. | Midwifery | Midwifery | 148 | null | 10.1016/j.midw.2025.104514 | eng | 2,025 | 9 | null | 2,025 | 7 | 8 | [PROBLEM] Despite the overwhelming benefits of midwifery-led care models, in many countries, for several reasons, there is a resistance to their implementation. [BACKGROUND] These care models provide both short-term and long-term advantages for mothers and newborn, demonstrate sustainability, and offer economic benefit... | Implementation science; Midwifery; Organisation & administration; Prenatal care; Systematic review | 0.981 | 91 | Maternity and Midwifery; Obstetrics and Gynecology | Medicine; Nursing | 2,024 |
40,669,249 | GDF15 attenuates sepsis-induced acute lung injury by suppressing the HIF-1α/LDHA pathway. | International immunopharmacology | Int Immunopharmacol | 163 | null | 10.1016/j.intimp.2025.115198 | eng | 2,025 | 7 | 15 | 2,025 | 7 | 15 | [BACKGROUND] Sepsis-associated acute lung injury (ALI) is characterized by endothelial inflammation and metabolic reprogramming. Growth Differentiation Factor 15 (GDF15), a stress-inducible cytokine, may regulate immunometabolic crosstalk, but its endothelial-specific role remains undefined. [METHODS] Using LPS-induced... | Acute lung injury; Endothelial dysfunction; GDF15; Immunometabolic crosstalk; Vascular hyperpermeability | 1.239 | 155 | Pharmacology; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,024 |
40,668,998 | Effect of simulated gastric acid on the mechanical properties of conventional and polypropylene mesh reinforced poly methyl methacrylate denture base resin. | Journal of Indian Prosthodontic Society | J Indian Prosthodont Soc | 25 | 3 | 10.4103/jips.jips_130_25 | eng | 2,025 | 7 | 1 | 2,025 | 7 | 16 | [AIM] Sustainability of dental polymethyl methacrylate (PMMA) in acidic environments is crucial as oral pH fluctuations can degrade the mechanical properties of denture bases. PMMA strengthening with polypropylene (PP) mesh has improved mechanical properties, but its effectiveness in acidic conditions remains underexpl... | Denture base resin; gastric acid; polymethyl methacrylate; polypropylene mesh | 0.41 | 35 | Dentistry; Oral Surgery | Dentistry | 2,024 |
40,668,865 | Molecular Phenotyping of Sepsis and Differential Response to Fluid Resuscitation. | American journal of respiratory and critical care medicine | Am J Respir Crit Care Med | null | null | 10.1164/rccm.202412-2377OC | eng | 2,025 | 7 | 16 | 2,025 | 7 | 16 | [RATIONALE] Biological heterogeneity in critical illness syndromes, such as sepsis and acute kidney injury (AKI), has hindered development of effective therapies. In sepsis-associated AKI, two molecular sub-phenotypes (SP1 and SP2) have been identified with differing characteristics, outcomes and response to vasopresso... | acute kidney injury; endothelial dysfunction; sepsis; vasopressors; volume | 5.076 | 436 | Critical Care and Intensive Care Medicine; Pulmonary and Respiratory Medicine | Medicine | 2,024 |
40,668,805 | Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic andiral Characteristics and Response to Dual and Extended Antiviral Therapy. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America | Clin Infect Dis | null | null | 10.1093/cid/ciaf383 | eng | 2,025 | 7 | 16 | 2,025 | 7 | 16 | [BACKGROUND] Immunocompromised patients remain at risk for protracted SARS-CoV-2 infections with persistent viral shedding that could pose a wider public health risk. The optimal therapeutic strategy remains unknown. [METHODS] We describe a sequential case series of immunocompromised adults with protracted SARS-CoV-2 i... | B-cell depleted; Dual antiviral therapy; Immunocompromised; Protracted Infection; SARS-CoV-2 | 2.992 | 398 | Infectious Diseases; Microbiology | Medicine | 2,024 |
40,668,711 | Dynamic Evaluation of Colitis-Associated Colorectal Cancer Using Multimodal US-OCT-NIRF System. | IEEE transactions on bio-medical engineering | IEEE Trans Biomed Eng | PP | null | 10.1109/TBME.2025.3589599 | eng | 2,025 | 7 | 16 | 2,025 | 7 | 16 | [OBJECTIVE] Colitis-associated colorectal cancer (CAC) poses a significant clinical challenge due to its poor prognosis and difficulty in distinguishing malignancy from inflammation with current imaging methods. This study aims to evaluate a multimodal endoscopic imaging system combining optical coherence tomography (O... | null | null | null | null | null | null |
40,668,513 | Using short video-based educational intervention to enhance initial acceptance to continuous positive pressure therapy in Thai obstructive sleep apnea patients in a tertiary care: a randomized controlled trial. | Sleep & breathing = Schlaf & Atmung | Sleep Breath | 29 | 4 | 10.1007/s11325-025-03419-8 | eng | 2,025 | 7 | 16 | 2,025 | 7 | 16 | [PURPOSE] Obstructive sleep apnea (OSA) is a prevalent condition associated with decreased quality of life and increased risk of cardiovascular complications. Continuous positive airway pressure (CPAP) therapy is the gold standard treatment, particularly in moderate to severe OSA. Its effectiveness depends on patient a... | Adherence; Continuous positive airway pressure; Obstructive sleep apnea syndrome | null | null | null | null | null |
40,668,056 | The Impact of Hospital-Level Median Door-to-Extracorporeal Cardiopulmonary Resuscitation Time on the Prognosis of Patients With Refractory Out-of-Hospital Cardiac Arrest. | Critical care medicine | Crit Care Med | null | null | 10.1097/CCM.0000000000006808 | eng | 2,025 | 7 | 16 | 2,025 | 7 | 16 | [OBJECTIVES] To evaluate the impact of hospital-level median door-to-extracorporeal cardiopulmonary resuscitation (ECPR) time on survival and neurologic outcomes in patients with out-of-hospital cardiac arrest (OHCA) requiring ECPR. [DESIGN] Secondary analysis of the Japanese Association for Acute Medicine OHCA registr... | extracorporeal cardiopulmonary resuscitation; neurological outcomes; out-of-hospital cardiac arrest; quality indicator; survival | 2.12 | 315 | Critical Care and Intensive Care Medicine | Medicine | 2,024 |
40,667,757 | Adding Non-Occlusive Cryoballoon Ablation in Case of Ostial-Level Pulmonary Vein Isolation or Carina Sparing Does Not Improve 1-Year Outcome After Cryoballoon Ablation (the NOCA-AF Study). | Journal of cardiovascular electrophysiology | J Cardiovasc Electrophysiol | null | null | 10.1111/jce.70011 | eng | 2,025 | 7 | 16 | 2,025 | 7 | 16 | [INTRODUCTION] Fixed-diameter cryoballoon ablation (CBA) can yield suboptimal ostial-level pulmonary vein isolation (PVI) and spare arrhythmogenic sites like the carina. The addition of non-occlusive cryoballoon ablation (NOCA) could overcome this limitation of CBA. We aimed to assess the need and effectiveness of NOCA... | atrial fibrillation; cryoballoon; pulmonary vein isolation | 1.187 | 154 | Cardiology and Cardiovascular Medicine; Physiology | Medicine | 2,024 |
40,667,507 | A full-spectrum Boswellia serrata extract with enhanced bioavailability, and its co-delivered system with curcumin alleviate pain and stiffness associated with moderate spondylitis: a randomized double-blind, placebo-controlled, 3-arm study. | Frontiers in pharmacology | Front Pharmacol | 16 | null | 10.3389/fphar.2025.1577429 | eng | 2,025 | null | null | 2,025 | 7 | 1 | [OBJECTIVE] Pain and stiffness at the neck, back, hip, and other joints due to conditions such as spondylitis or spondylosis are significant musculoskeletal concerns globally. The present study evaluated the relative efficacy of a bioavailability enhanced full-spectrum extract of Boswellia serrata Roxb. oleo-gum resin ... | Curcumin; bioavailability; boswellia; neck/back/joint pain; spondylitis | 1.22 | 175 | Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,024 |
40,667,444 | Association between triglyceride glucose-waist-adjusted waist index and incident stroke in Chinese adults: a prospective cohort study. | Frontiers in nutrition | Front Nutr | 12 | null | 10.3389/fnut.2025.1612864 | eng | 2,025 | null | null | 2,025 | 7 | 1 | [OBJECTIVE] Current literature lacks evidence on the association between the triglyceride glucose-weight-adjusted waist index (TyG-WWI) and incident stroke. Therefore, this study aims to elucidate the relationship between TyG-WWI and stroke risk in a nationally representative cohort of middle-aged and elderly Chinese a... | TYG-WWI; insulin resistance; nonlinear association; smooth curve fitting; stroke | 1.115 | 94 | Food Science; Nutrition and Dietetics; Endocrinology, Diabetes and Metabolism | Agricultural and Biological Sciences; Medicine; Nursing | 2,024 |
40,666,395 | Analysis of Cases of Mild Head Trauma Resulting in Fatal Outcome from the Doctor Helicopter Registry Data. | Journal of emergencies, trauma, and shock | J Emerg Trauma Shock | 18 | 2 | 10.4103/jets.jets_87_24 | eng | 2,025 | null | null | 2,025 | 6 | 19 | [INTRODUCTION] In cases of mild head trauma, there have been no comprehensive studies on cases that resulted in death. This study aims to conduct a factor analysis of mild head trauma cases resulting in death. Patients with Glasgow Coma Scale (GCS) scores of 14 or 15 in the Japan Doctor Helicopter (DH) Registration Sys... | Fatal outcome; helicopter; mild head injury | 0.309 | 42 | Emergency Medicine | Medicine | 2,024 |
40,666,213 | The relationship between work addiction and addictions to social media, shopping, food, caffeine, and nicotine. | Australian journal of psychology | Aust J Psychol | 77 | 1 | 10.1080/00049530.2025.2486774 | eng | 2,025 | null | null | 2,025 | 4 | 2 | [PURPOSE] Work addiction is a relatively underexplored behaviour compared to other forms of addiction. Existing research predominantly focuses on the antecedents and consequences of work addiction. However, studies examining its relationship with other types of addiction are notably limited. Therefore the present study... | Work addiction; addiction comorbidity; behavioural addictions; caffeine addiction; food addiction; nicotine addiction; shopping addiction; social media addiction | 1.477 | 56 | Psychology | Psychology | 2,024 |
40,666,178 | Tanshinone IIA alleviates liver fibrosis by suppressing hepatic stellate cell proliferation via ERK/cyclin D1/p-Smad3L signaling axis. | Iranian journal of basic medical sciences | Iran J Basic Med Sci | 28 | 5 | 10.22038/ijbms.2025.83092.17962 | eng | 2,025 | null | null | null | null | null | [OBJECTIVES] Liver fibrosis (LF) is a critical stage in chronic liver disease progression, and effective therapeutic drugs are currently lacking. Tanshinone IIA (Tan IIA), a monomer extracted from Salvia miltiorrhiza, shows potential in treating LF. This research aims to discuss the antifibrotic efficacy and underlying... | Hepatic stellate cells; Liver fibrosis; Tanshinone IIA | null | null | null | null | null |
40,666,159 | Case Report: Overlooked Skin Melanoma Unveiled by Gastric Metastasis. | F1000Research | F1000Res | 13 | null | 10.12688/f1000research.155815.4 | eng | 2,024 | null | null | 2,025 | 7 | 3 | [BACKGROUND] Gastric metastasis from melanoma is rare and often presents as an unexpected finding, rarely revealing an underlying primary skin melanoma. [CASE PRESENTATION] We report a case of a 62-year-old male who presented with abdominal pain, dyspepsia, anorexia, and weight loss. On physical examination abdominal m... | Digestive endoscopy; Gastric metastasis; Histopathology; Melanoma; Multi-organ metastases | 0.537 | 119 | Arts and Humanities; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Library and Information Sciences; Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences | Arts and Humanities; Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics; Social Sciences | 2,024 |
40,665,776 | The Effectiveness of Oxytocin for Preventing Postpartum Haemorrhage: An Individual Participant Data Meta-Analysis. | BJOG : an international journal of obstetrics and gynaecology | BJOG | null | null | 10.1111/1471-0528.18279 | eng | 2,025 | 7 | 16 | 2,025 | 7 | 16 | [BACKGROUND] Post-partum haemorrhage (PPH) is a common complication of labour. [OBJECTIVE] To assess the effectiveness of oxytocin in comparison to no treatment for preventing PPH. [SELECTION CRITERIA] Published and unpublished randomised controlled trials (RCTs) comparing systemic oxytocin to placebo or no interventio... | oxytocin; postpartum haemorrhage; randomised controlled trial | 1.786 | 195 | Obstetrics and Gynecology | Medicine | 2,024 |
40,665,668 | Impact of Warmed Irrigation Fluid During Shoulder Arthroscopy on Patient Temperature, Recovery, and Cognitive Function: A Prospective Analysis of Influencing Factors. | Orthopaedic surgery | Orthop Surg | 17 | 8 | 10.1111/os.70123 | eng | 2,025 | 8 | null | 2,025 | 7 | 15 | [OBJECTIVE] To investigate the effects of warmed irrigation fluid during shoulder arthroscopy on patient temperature regulation, recovery outcomes, and cognitive function. [METHODS] A randomized single-blind prospective study (Level II) and a total of 85 patients who underwent shoulder arthroscopy at our hospital from ... | Montreal Cognitive Assessment; arthroscopy; hypothermia; irrigation | 0.724 | 46 | Surgery; Orthopedics and Sports Medicine | Medicine | 2,024 |
40,665,331 | MicroRNAs in the diagnosis of osteoarthritis: a systematic review and meta-analysis of observational studies. | Journal of orthopaedic surgery and research | J Orthop Surg Res | 20 | 1 | 10.1186/s13018-025-06059-6 | eng | 2,025 | 7 | 15 | 2,025 | 7 | 15 | [BACKGROUND] In recent years, the diagnostic and prognostic values of microRNAs (miRNAs) in different diseases have been extensively studied. Therefore, a meta-analysis of miRNAs has been performed to unravel whether miRNAs could be novel diagnostic markers for osteoarthritis (OA). [METHODS] In this meta-analysis, Coch... | Diagnosis; Meta-analysis; MiRNA; Osteoarthritis | 0.877 | 75 | Orthopedics and Sports Medicine; Surgery | Medicine | 2,024 |
40,665,315 | Impact of diabetes mellitus on myocardial function and clinical outcomes in patients with significant aortic regurgitation. | Cardiovascular diabetology | Cardiovasc Diabetol | 24 | 1 | 10.1186/s12933-025-02843-0 | eng | 2,025 | 7 | 15 | 2,025 | 7 | 15 | [BACKGROUND] Type 2 diabetes mellitus (T2DM) causes myocardial dysfunction and has been linked to an increased risk of unfavorable cardiovascular events. However, the additive effects of T2DM on myocardial function and its association with clinical outcomes in patients with aortic regurgitation (AR) is undetermined. Th... | Aortic regurgitation; Diabetes mellitus; Echocardiography; Myocardial function; Strain | 3.353 | 121 | Cardiology and Cardiovascular Medicine; Endocrinology, Diabetes and Metabolism; Internal Medicine | Medicine | 2,024 |
40,665,292 | Interpretable prediction of hospital mortality in bleeding critically ill patients based on machine learning and SHAP. | BMC medical informatics and decision making | BMC Med Inform Decis Mak | 25 | 1 | 10.1186/s12911-025-03101-9 | eng | 2,025 | 7 | 15 | 2,025 | 7 | 15 | [BACKGROUND] Hemorrhage is a prevalent and critical condition in the intensive care unit (ICU), characterized by high incidence, elevated mortality rates, and substantial therapeutic challenges. Accurate prediction of mortality in patients with hemorrhage is essential for developing personalized prevention and treatmen... | Hemorrhage; Intensive care unit; Prediction; SHAP; XGBoost | 1.041 | 107 | Computer Science Applications; Health Policy; Health Informatics | Computer Science; Medicine | 2,024 |
40,712,730 | Barriers to immediate postpartum long-acting reversible contraceptive provision in China: A qualitative study from the perspective of service providers. | Contraception | Contraception | null | null | 10.1016/j.contraception.2025.111040 | eng | 2,025 | 7 | 23 | 2,025 | 7 | 23 | [OBJECTIVES] This study aimed to explore the barriers to immediate postpartum long-acting reversible contraception provision (LARC) from the perspective of obstetric health care providers in China. [STUDY DESIGN] The qualitative study involved hospital deputy directors, obstetric department chiefs, doctors, and nurses ... | Barriers; In-depth interview; Long-acting reversible contraception; Postpartum; Service providers | 1.334 | 118 | Obstetrics and Gynecology; Reproductive Medicine | Medicine | 2,024 |
40,712,709 | Temporal and geographical trends in anticoagulant therapy and catheter ablation for atrial fibrillation in Japan, 2014-2022. | Journal of cardiology | J Cardiol | null | null | 10.1016/j.jjcc.2025.07.008 | eng | 2,025 | 7 | 23 | 2,025 | 7 | 23 | [BACKGROUND] In the past decade, treatment of atrial fibrillation (AF) has dramatically changed. Geographical variations and associated factors influencing implementation of anticoagulant therapy and catheter ablation for AF have not been completely elucidated. This study aimed to investigate the temporal and geographi... | Atrial fibrillation; Catheter ablation; Direct oral anticoagulants; Socioeconomic status | 0.915 | 66 | Cardiology and Cardiovascular Medicine | Medicine | 2,024 |
40,712,433 | MetInfilt: A prospective trial highlighting the importance of the histological growth pattern in brain metastases. | Translational oncology | Transl Oncol | 60 | null | 10.1016/j.tranon.2025.102480 | eng | 2,025 | 10 | null | 2,025 | 7 | 24 | [BACKGROUND] While the histological growth pattern (HGP) of liver metastases is frequently evaluated, the same attention is often absent for brain metastases despite evidence suggesting its prognostic significance. This oversight may stem from the lack of a standardized method for assessing the HGP at the macro-metasta... | Brain metastasis; CONVIVO; HGP; MMPI; MRI; MetInfilt; meningeal metastasis | 1.408 | 78 | Oncology; Cancer Research | Biochemistry, Genetics and Molecular Biology; Medicine | 2,024 |
40,712,369 | Enhancing cardiac hemodynamic and pulsatility in heart failure via deep reinforcement learning: An in-silico and in-vitro validation study of percutaneous ventricular assist devices. | Computer methods and programs in biomedicine | Comput Methods Programs Biomed | 270 | null | 10.1016/j.cmpb.2025.108975 | eng | 2,025 | 10 | null | 2,025 | 7 | 18 | [BACKGROUND AND OBJECTIVE] Percutaneous ventricular assist devices (pVADs) are critical for bridging heart failure (HF) patients to recovery or transplantation, yet existing control strategies-constant speed control and preprogrammed pulsatile control-lack adaptability to dynamic physiological variations, leading to re... | Adaptive control; Deep reinforcement learning; Heart failure; Hemodynamics; Pulsatility; Ventricular assist devices | 1.13 | 150 | Computer Science Applications; Health Informatics; Software | Computer Science; Medicine | 2,024 |
40,712,347 | The impact of COVID-19 and socio-economic crisis on primary hyperparathyroidism patients in Lebanon: A trend to operate more acute and advanced-stage cases. | American journal of otolaryngology | Am J Otolaryngol | 46 | 5 | 10.1016/j.amjoto.2025.104713 | eng | 2,025 | 7 | 22 | 2,025 | 7 | 22 | [BACKGROUNDS] Evaluate contribution of COVID-19 pandemic, the socio-economic crisis, and explosion of Beirut port to a concerning trend of operating on more advanced-stage in primary hyperparathyroism (PHPT). [METHODS] We included all patients operated for PHPT between 1997 and 2024. Two groups were established: Group ... | Advanced stage disease; COVID-19; Economic crisis; Primary hyperparathyroidism; Surgery | null | null | null | null | null |
40,711,413 | The Impact of Screw Density on the Outcomes of Adolescent Idiopathic Scoliosis Correction Surgery: A Multicenter Retrospective Study. | Journal of investigative surgery : the official journal of the Academy of Surgical Research | J Invest Surg | 38 | 1 | 10.1080/08941939.2025.2531589 | eng | 2,025 | 12 | null | 2,025 | 7 | 25 | [BACKGROUND] To evaluate the efficacy of low screw density constructs versus high screw density constructs in adolescent idiopathic scoliosis (AIS) surgery. [METHODS] Data were collected from AIS patients who underwent pedicle screw fixation surgery at two medical centers. Patients were stratified into low and high scr... | AIS; adolescent idiopathic scoliosis; radiographic; screw density; short-term outcomes | 0.595 | 48 | Surgery | Medicine | 2,024 |
40,711,156 | Increased Cardiovascular Mortality in Hemodialysis: The Role of Chronic Inflammation, Complement Activation, and Non-Biocompatibility. | Toxins | Toxins (Basel) | 17 | 7 | 10.3390/toxins17070345 | eng | 2,025 | 7 | 10 | 2,025 | 7 | 10 | [BACKGROUND] Chronic kidney disease (CKD) is an established global health problem, with the increased prevalence of vascular inflammation, accelerated atherogenesis, and thrombotic risk all contributing to overall cardiovascular risk. The major CKD-specific risk factor is presumed to be the accumulation of uremic toxin... | biocompatibility; chronic inflammation; complement activation; hemodialysis; immunological; mortality; peritoneal dialysis | 1.051 | 128 | Health, Toxicology and Mutagenesis; Toxicology | Environmental Science; Pharmacology, Toxicology and Pharmaceutics | 2,024 |
40,711,083 | Using Respiratory Gas Analyzers to Determine Resting Metabolic Rate in Adults: A Systematic Review of Validity Studies. | Sports (Basel, Switzerland) | Sports (Basel) | 13 | 7 | 10.3390/sports13070198 | eng | 2,025 | 6 | 22 | 2,025 | 6 | 22 | [BACKGROUND] Correct assessment of resting metabolic rate (RMR) is fundamental for estimating total energy expenditure in both clinical nutrition and sports sciences research. Various methods have been proposed for RMR determination, including predictive equations, isotopic dilution techniques, and indirect calorimetry... | energetic expenditure; indirect calorimetry; reproducibility of results; validation study | 0.922 | 48 | Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation | Health Professions; Medicine | 2,024 |
40,710,959 | The Speech Intelligibility Index: Tutorial and Applications for Children Who Are Deaf and Hard of Hearing. | American journal of audiology | Am J Audiol | null | null | 10.1044/2025_AJA-24-00267 | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [PURPOSE] Speech audibility refers to how much access a listener has to the acoustic cues that comprise spoken communication. The Speech Intelligibility Index (SII) is a measure of speech audibility that has had increasing use in pediatric audiology to quantify auditory access with and without hearing aids. This tutori... | null | 0.684 | 57 | Speech and Hearing | Health Professions | 2,024 |
40,709,991 | Subcutaneous Panniculitis-like T-Cell Lymphoma: Diagnostic Challenge and Successful Multimodal Management with Integra[®] Dermal Matrix-Case Report and Review of the Literature. | Diseases (Basel, Switzerland) | Diseases | 13 | 7 | 10.3390/diseases13070201 | eng | 2,025 | 6 | 30 | 2,025 | 6 | 30 | [BACKGROUND/OBJECTIVES] Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare and aggressive cutaneous lymphoma, often misdiagnosed due to nonspecific clinical features. Early diagnosis and treatment remain challenging. [METHODS] We report the case of a 31-year-old female with a chronic non-healing gluteal w... | chemotherapy; dermal matrix; lymphoma; soft tissue defects | 0.851 | 26 | Medicine | Medicine | 2,024 |
40,709,867 | A Meta-Analysis of ChatGPT's Performance on Dermatology Specialty-Level (Board-Style) Certification QuestionsAbstract. | Indian dermatology online journal | Indian Dermatol Online J | null | null | 10.4103/idoj.idoj_1250_24 | eng | 2,025 | 7 | 23 | 2,025 | 7 | 23 | [BACKGROUND AND OBJECTIVE] ChatGPT, an advanced artificial intelligence chatbot, has shown promise in various medical applications, including dermatology. This meta-analysis evaluates its performance on dermatology specialty (board-style) certification questions based on evidence from multiple studies. [MATERIALS AND M... | null | 0.532 | 24 | Dermatology; Immunology and Allergy; Infectious Diseases; Microbiology | Medicine | 2,024 |
40,709,085 | A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma. | Frontiers in pharmacology | Front Pharmacol | 16 | null | 10.3389/fphar.2025.1605515 | eng | 2,025 | null | null | 2,025 | 7 | 10 | [INTRODUCTION] Hepatocellular carcinoma (HCC) ranks among the three most prevalent cancer-related diseases in terms of incidence. Hence, exploring drugs for HCC therapy is of great significance. Compounds with a diaryl urea structure have been reported to exhibit a broad range of biological activities, including antica... | RAS/RAF/MEK/ERK; bioactive compound; cell proliferation; diaryl urea derivative; hepatocellular carcinoma | 1.22 | 175 | Pharmacology; Pharmacology | Medicine; Pharmacology, Toxicology and Pharmaceutics | 2,024 |
40,708,650 | Pancreatic stone protein inhibits pyroptosis of pancreatic acinar cells in sepsis-associated pancreatic injury. | Frontiers in medicine | Front Med (Lausanne) | 12 | null | 10.3389/fmed.2025.1566728 | eng | 2,025 | null | null | 2,025 | 7 | 10 | [INTRODUCTION] Sepsis-associated pancreatic injury (SPI) is characterized by an increased incidence and significantly higher mortality rates. However, its underlying pathogenesis remains inadequately understood. As an acute-phase protein secreted by the pancreas, the role of pancreatic stone protein/regenerating protei... | pancreatic injury; pancreatic stone protein; pyroptosis; regenerating protein; sepsis | 0.962 | 102 | Medicine | Medicine | 2,024 |
40,708,521 | Comprehensive Meta-Analysis on the Impact of the MDM2 SNP 309 T>G Gene Variant in Leukemia Susceptibility. | Current pharmaceutical design | Curr Pharm Des | null | null | 10.2174/0113816128368759250527073556 | eng | 2,025 | 7 | 23 | 2,025 | 7 | 23 | [INTRODUCTION] Genetic factors play a significant role in the development of leukemia. The overexpression of MDM2 is associated with the progression of certain leukemias. This meta-analysis investigates the relationship between the MDM2 SNP 309T>G and various forms of leukemia across global populations. [METHODS] A com... | AML; CML.; MDM2 309 SNP T>G; leukemia; meta-analysis; rs2279744 | 0.611 | 190 | Drug Discovery; Pharmacology | Pharmacology, Toxicology and Pharmaceutics | 2,024 |
40,708,112 | Neighborhood sociome factors and pediatric asthma exacerbations: Protective role of tree crown density and importance of pharmacy access in Chicago's south side. | Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology | Pediatr Allergy Immunol | 36 | 7 | 10.1111/pai.70127 | eng | 2,025 | 7 | null | null | null | null | [BACKGROUND] Pediatric asthma exacerbations remain a critical public health concern, particularly in historically underserved urban settings. [OBJECTIVE] This study investigates sociome factors-the social context of disease-associated with asthma exacerbations among children living in Chicago's South Side, leveraging c... | Chicago; SDOH; health disparities; pediatric asthma; social determinants of health; sociome; trees | 1.269 | 108 | Pediatrics, Perinatology and Child Health; Immunology; Immunology and Allergy | Immunology and Microbiology; Medicine | 2,024 |
40,707,917 | A systematic scoping review of mentor training in medical education between 2000 and 2024. | BMC medical education | BMC Med Educ | 25 | 1 | 10.1186/s12909-025-07353-x | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [BACKGROUND] Effective mentoring in medical education facilitates professional development amongst mentees and mentors, improves patient care and outcomes, as well as advances the reputation of the host organisation. Much of this success is guided, assessed and overseen by the mentor. Yet, mentor training remains incon... | Medical schools; Medicine; Mentee; Mentor; Mentor training; Mentoring; Professional identity formation | 0.947 | 107 | Education; Medicine | Medicine; Social Sciences | 2,024 |
40,707,901 | Beyond labels: determining the true type of blood gas samples in ICU patients through supervised machine learning. | BMC medical informatics and decision making | BMC Med Inform Decis Mak | 25 | 1 | 10.1186/s12911-025-03115-3 | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [BACKGROUND] In the Intensive Care Unit (ICU), data stored in patient data management systems (PDMS) is commonly used in clinical practice and research. Parameters from point-of-care arterial blood gas (BG) analysis are used in the diagnosis and definition of syndromes such as sepsis and ARDS, but manual entry of the b... | Adult; Biochemistry; Blood gas; ICU; Intensive care; Pediatric; Supervised machine learning | 1.041 | 107 | Computer Science Applications; Health Policy; Health Informatics | Computer Science; Medicine | 2,024 |
40,707,745 | Attitudes of Gastroenterologists Regarding Preoperative Anxiety Prior to Colonoscopy: A Cross-Sectional Study. | Digestive diseases and sciences | Dig Dis Sci | null | null | 10.1007/s10620-025-09239-w | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [BACKGROUND] Colonoscopy is often considered by patients to be an anxiety-provoking procedure. Studies have investigated different approaches to help alleviate anxiety prior to colonoscopies. However, there have been no investigations of gastroenterologists and their attitudes towards pre-procedural anxiety of patients... | Anxiety; Colonoscopy; Education; Survey | 1.004 | 146 | Gastroenterology; Physiology | Biochemistry, Genetics and Molecular Biology; Medicine | 2,024 |
40,707,312 | Exploring experiences of orthognathic surgery: A Reddit-based content analysis. | Journal of the World federation of orthodontists | J World Fed Orthod | null | null | 10.1016/j.ejwf.2025.06.001 | eng | 2,025 | 7 | 23 | 2,025 | 7 | 23 | [BACKGROUND] Gaps in presurgical consultations may lead individuals to seek information and support on the internet. Social media, including Reddit, may offer emotional reassurance and peer-driven insights. This study aims to explore key themes, user sentiment, and Reddit's role in shaping orthognathic surgery experien... | Orthodontics; Orthognathic surgery; Patient experiences; Reddit | 0.963 | 19 | Orthodontics | Dentistry | 2,024 |
40,707,283 | Accuracy of continuous glucose monitoring during noncardiac surgery: a prospective, blinded observational multicentre cohort study. | British journal of anaesthesia | Br J Anaesth | null | null | 10.1016/j.bja.2025.05.057 | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [BACKGROUND] Hyperglycaemia after noncardiac surgery is rarely detected outside of the critical care environment, yet occurs commonly and is associated with excess complications including infections and myocardial injury. Systematic, prospectively collected data regarding the accuracy of continuous glucose monitoring c... | complications; glucose monitoring; hyperglycaemia; noncardiac surgery; perioperative care | 2.36 | 222 | Anesthesiology and Pain Medicine | Medicine | 2,024 |
40,707,243 | VISUAL FLOW study: Ophthalmologic outcomes following carotid aneurysm treatment using a flow-diverter stent covering the origin of the ophthalmic artery in patients under dual antiplatelet therapy with aspirin and ticagrelor. | Journal of neurointerventional surgery | J Neurointerv Surg | null | null | 10.1136/jnis-2025-023462 | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [INTRODUCTION] The use of flow-diverting stents (FDS) for intracranial aneurysms has become common practice. This study aimed to evaluate ophthalmologic outcomes following carotid-ophthalmic aneurysm treatment with an FDS covering the origin of the ophthalmic artery in patients receiving aspirin and ticagrelor, through... | Aneurysm; Flow Diverter; Orbit; Platelets | 1.634 | 90 | Medicine; Neurology; Surgery | Medicine | 2,024 |
40,706,465 | The Nursing Student Self-Efficacy in Clinical Skills Scale (NSSE-CS): A development and psychometric validation study. | Nurse education in practice | Nurse Educ Pract | 87 | null | 10.1016/j.nepr.2025.104479 | eng | 2,025 | 7 | 18 | 2,025 | 7 | 18 | [AIM] Develop and validate a scale that measures nursing students' self-efficacy (SE) in performing core clinical skills typically acquired during undergraduate clinical placements. [BACKGROUND] Student perceptions of SE can enhance motivation, foster improvement and serve as a robust predictor of academic achievement.... | Baccalaureate nursing education; Clinical competence; Nursing students; Professional education; Self-assessment; Self-efficacy | 1.129 | 68 | Education; Medicine; Nursing | Medicine; Nursing; Social Sciences | 2,024 |
40,705,971 | The Association Between Autoimmune Rheumatic Diseases and Depression: A Two-Sample Bidirectional Mendelian Randomization. | Psychiatry | Psychiatry | null | null | 10.1080/00332747.2025.2528526 | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [BACKGROUND] Although prior observational studies have indicated an association between depression and autoimmune rheumatic diseases (ARDs), the underlying causal relationship remains unclear. [METHODS] A two-sample bidirectional Mendelian randomization (MR) study was conducted to explore the causal link between depres... | null | null | null | null | null | null |
40,705,942 | Characteristics of Hemodialysis Patients and Renal Transplant Recipients Undergoing Cardiovascular Intervention: Is It Possible to Predict Cardiac Risk? | Brazilian journal of cardiovascular surgery | Braz J Cardiovasc Surg | 40 | 4 | 10.21470/1678-9741-2024-0291 | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [INTRODUCTION] Cardiovascular problems are one of the major causes of morbidity and mortality among renal transplant and hemodialysis patients. This study evaluates the preoperative risk factors and postoperative outcomes in patients undergoing heart surgery. [METHODS] A total of 83 patients (47 post-renal transplant r... | Acute Kidney Injury; Cardiac Surgical Procedures; Insulin Resistance.; Renal Dialysis; Selection Bias | 0.341 | 36 | Cardiology and Cardiovascular Medicine; Medicine; Surgery | Medicine | 2,024 |
40,705,937 | Living Will: A Cross-Sectional Study on the Perspective, Knowledge, and Clinical Use of General Practitioners in Portugal. | Journal of evaluation in clinical practice | J Eval Clin Pract | 31 | 5 | 10.1111/jep.70213 | eng | 2,025 | 8 | null | null | null | null | [RATIONALE] In Portugal, living wills-legal documents allowing individuals to express healthcare preferences in case of future incapacity-have been recognized since 2012. Despite this, public engagement remains limited, and previous studies have highlighted both public unawareness and knowledge gaps among healthcare pr... | Advance Directives; General Practitioners; advance care planning; living will; primary care | 0.799 | 91 | Health Policy; Public Health, Environmental and Occupational Health | Medicine | 2,024 |
40,705,782 | Clinical outcomes of a novel single-stage cartilage repair technique using calcified cartilage zone debridement with hyalofast. | PloS one | PLoS One | 20 | 7 | 10.1371/journal.pone.0328978 | eng | 2,025 | null | null | 2,025 | 7 | 24 | [INTRODUCTION] This study aims to determine the clinical outcomes of a new technique of cartilage repair surgery, using calcified cartilage zone debridement coupled with Hyalofast and bone marrow aspirate concentrate, in terms of pain and functional outcomes. [METHODS] This was a retrospective case series in 19 patient... | null | 0.803 | 467 | Multidisciplinary | Multidisciplinary | 2,024 |
40,705,613 | Cognitive performance fatigability, perceived fatigability, and trait fatigue in post-COVID-19 condition: A cross-sectional study. | Neuropsychology | Neuropsychology | null | null | 10.1037/neu0001020 | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [OBJECTIVE] Earlier research on fatigue in post-COVID-19 condition (PCC) has mainly studied subjective fatigue, either over a prolonged period (trait fatigue) or in relation to a certain situation (state fatigue) in the form of perceived fatigability. Another aspect of state fatigue, cognitive performance fatigability,... | null | 1.002 | 150 | Neuropsychology and Physiological Psychology | Psychology | 2,024 |
40,705,116 | A prospective, multi-centre trial of PSMA-PET compared to FDG-PET for staging of newly diagnosed high risk prostate cancer. | EJNMMI research | EJNMMI Res | 15 | 1 | 10.1186/s13550-025-01265-z | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [BACKGROUND] Despite being a potentially attractive alternative molecular imaging modality due to wider availability and association with lethal disease in advanced prostate cancer, the role of fluorodeoxyglucose (FDG)- positron emission tomography (PET) at initial diagnosis compared to Prostate Specific Membrane Antig... | 18F-FDG; Cancer staging; PET/CT; PSMA; Prostate cancer; Prostate-specific membrane antigen | 0.94 | 58 | Radiology, Nuclear Medicine and Imaging | Medicine | 2,024 |
40,704,902 | Mitochondrial Fitness Science Communication: A Qualitative Study. | Journal of the American Geriatrics Society | J Am Geriatr Soc | null | null | 10.1111/jgs.70019 | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [BACKGROUND] Geroscience explores aging at the cellular level. We developed a lay-friendly science communication intervention (MitoFit) that addresses healthy aging through mitochondrial fitness. The intervention aims to promote physical activity by educating aging adults about optimizing mitochondrial function to prom... | geroscience; mitochondrial fitness; older adults; physical activity; science communication | 1.889 | 273 | Geriatrics and Gerontology | Medicine | 2,024 |
40,704,643 | Timing of stroke risk reassessment in atrial fibrillation patients with CHA2DS2-VA score of 0 or 1: the Norwegian AFNOR study. | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology | Europace | null | null | 10.1093/europace/euaf145 | eng | 2,025 | 7 | 24 | 2,025 | 7 | 24 | [BACKGROUND AND AIMS] Stroke risk in atrial fibrillation (AF) patients increases over time, but the optimal reassessment interval remains unclear. This study evaluated changes in the CHA2DS2-VA score in AF patients with low (score 0) or intermediate (score 1) stroke risk and explored appropriate reassessment intervals.... | atrial fibrillation; dynamic care; reassessment; risk factors; stroke prevention | null | null | null | null | null |
40,704,226 | CHIP toolkit: Social mapping and transect walk for childhood infection and pollution - A comparative study across four cities (Jaipur, Jakarta, Antofagasta, and Istanbul). | One health (Amsterdam, Netherlands) | One Health | 21 | null | 10.1016/j.onehlt.2025.101126 | eng | 2,025 | 12 | null | 2,025 | 7 | 9 | [BACKGROUND] The Sustainable Development Goals Agenda 2030 underscores the value of sustainable cities, clean water, sanitation, and well-being. In-spite of several improvements, the under-five mortality rates remain quite high, especially in inadequately serviced peri-urban settlements, wherein the environmental condi... | Childhood infections; Environmental health; One health; Social mapping; Sustainable development; Transect walks; Urban slums | 1.202 | 43 | Infectious Diseases; Public Health, Environmental and Occupational Health | Medicine | 2,024 |
40,704,128 | Childhood cigarette smoking is associated with health-related quality of life in older US adults. | Tobacco induced diseases | Tob Induc Dis | 23 | null | 10.18332/tid/204009 | eng | 2,025 | null | null | 2,025 | 7 | 23 | [INTRODUCTION] Childhood smoking onset is associated with chronic obstructive pulmonary disease (COPD), independent of current smoking and smoking history. Its association with lower quality of life has not been tested. We examined the association between childhood smoking and measures of global health among older US a... | childhood smoking; cigarette smoking; health-related quality of life | 0.665 | 41 | Health; Medicine; Public Health, Environmental and Occupational Health | Medicine; Social Sciences | 2,024 |
40,704,087 | Dynamic Femur Fracture Brace vs Hip Spica Cast for Pediatric Femoral Shaft Fractures: A Retrospective Comparative Cohort Study. | Journal of the Pediatric Orthopaedic Society of North America | J Pediatr Soc North Am | 12 | null | 10.1016/j.jposna.2025.100203 | eng | 2,025 | 8 | null | 2,025 | 5 | 23 | [BACKGROUND] Femoral shaft fractures constitute 1.6% of pediatric fractures and are a leading cause of pediatric orthopaedic hospitalization. The prefabricated DF2 functional brace offers an alternative to traditional spica casting, which is effective but has limitations. This study compares short-term outcomes and com... | Femoral shaft fracture; Functional brace; Pediatric fracture; Spica cast | null | null | null | null | null |
40,703,882 | Lipid Profile Pattern among Women Screened for Hyperglycaemia in Pregnancy at the University of Jos Teaching Hospital, Nigeria. | Nigerian medical journal : journal of the Nigeria Medical Association | Niger Med J | 66 | 2 | 10.71480/nmj.v66i2.516 | eng | 2,025 | null | null | 2,025 | 6 | 16 | [BACKGROUND] Hyperglycaemia in pregnancy (HIP) represents one of the most common medical challenges in pregnancy and the leading cause of adverse pregnancy outcomes the world over. Normal pregnancy is characterized by physiological adaptations such as progressive gestation-dependent increases in maternal triglycerides ... | Dyslipidaemia; Hyperglycaemia In Pregnancy; Lipids; Lipoproteins; Small Dense LDL Cholestero | null | null | null | null | null |
40,703,870 | Pattern of electrocardiographic and echocardiographic findings amongst Nigeria national football team players. | Nigerian medical journal : journal of the Nigeria Medical Association | Niger Med J | 66 | 2 | 10.71480/nmj.v66i2.594 | eng | 2,025 | null | null | 2,025 | 6 | 16 | [BACKGROUND] Cardiac adaptations in athletes, particularly football players, often result in distinct electrocardiographic (ECG) and echocardiographic changes. This study evaluates these cardiac patterns in Nigerian national football players compared to matched non-athlete controls. [METHODOLOGY] A case-control study w... | Echocardiography; Electrocardiography; Hypertrophic Cardiomyopathy; Nigerian National Football Team | null | null | null | null | null |
40,703,753 | Cinnamaldehyde ameliorates obesity-induced nephropathy in C57BL/6 mice via modulation of AMPK/ACC and NF-kB pathways. | Iranian journal of basic medical sciences | Iran J Basic Med Sci | 28 | 7 | 10.22038/ijbms.2025.83913.18157 | eng | 2,025 | null | null | null | null | null | [OBJECTIVES] Chronic kidney disease (CKD) is a life-threatening condition often resulting from obesity and other pathologies. The present study assesses the nephroprotective effect of Cinnamaldehyde against high-fat diet (HFD) obesity-associated nephropathy in rodents. [MATERIALS AND METHODS] The molecular docking anal... | AMPK pathway; Cinnamaldehyde; Inflammation; NF-kB pathway; Oxidative stress | null | null | null | null | null |
40,703,273 | Comparison of analgesic effects between betamethasone and dexamethasone in total knee arthroplasty: a prospective randomized controlled trial. | Frontiers in medicine | Front Med (Lausanne) | 12 | null | 10.3389/fmed.2025.1575417 | eng | 2,025 | null | null | 2,025 | 7 | 9 | [BACKGROUND] Corticosteroids such as dexamethasone and betamethasone are widely used for local infiltration analgesia in total knee arthroplasty (TKA). However, the analgesic efficacy of these two glucocorticoids in TKA cocktail therapy remains unknown. Therefore, this study aims to compare the analgesic efficacy and s... | betamethasone; cocktail therapy; dexamethasone; pain; total knee arthroplasty | 0.962 | 102 | Medicine | Medicine | 2,024 |
40,703,137 | Clustering of electronic health records in atrial fibrillation patients and impact on prognosis and patient trajectories: a UK linked-dataset study. | European heart journal. Digital health | Eur Heart J Digit Health | 6 | 4 | 10.1093/ehjdh/ztaf032 | eng | 2,025 | 7 | null | 2,025 | 4 | 5 | [AIMS] Atrial fibrillation (AF) is characterized by heterogeneity in presentation, comorbidity profile and prognosis, with different AF subphenotypes having been previously suggested. Mental health disorders are common in the AF population. The current classification of AF, based on episode duration, fails to capture t... | Anxiety; Atrial fibrillation; Depression; Electronic health records; Unsupervised Machine Learning | 1.494 | 21 | Cardiology and Cardiovascular Medicine | Medicine | 2,024 |
40,703,115 | Synthetic electrocardiograms for Brugada syndrome: from data generation to expert cardiologists evaluation. | European heart journal. Digital health | Eur Heart J Digit Health | 6 | 4 | 10.1093/ehjdh/ztaf039 | eng | 2,025 | 7 | null | 2,025 | 4 | 24 | [AIMS] Synthetic electrocardiograms (ECGs) for inherited cardiac diseases may overcome the issue related to data scarcity for artificial intelligence (AI)-based algorithms. This study aimed to evaluate experienced cardiologists' ability to differentiate synthetic and real Brugada ECGs. [METHODS AND RESULTS] A total of ... | AI-enabled ECG; Artificial Intelligence; Brugada Syndrome; Cardiogenetics; Machine learning; Synthetic ECG | 1.494 | 21 | Cardiology and Cardiovascular Medicine | Medicine | 2,024 |
40,702,914 | Postoperative Pain After Root Canal Preparation With Different Instruments in Primary Teeth: A Systematic Review and Meta-Analysis. | Clinical and experimental dental research | Clin Exp Dent Res | 11 | 4 | 10.1002/cre2.70180 | eng | 2,025 | 8 | null | null | null | null | [OBJECTIVE] This systematic review and meta-analysis aimed to evaluate the effectiveness of different instrumentation systems in reducing postoperative pain following root canal preparation in primary teeth. [MATERIAL AND METHODS] The present study was conducted in accordance with PRISMA guidelines and registered on PR... | endodontic treatment; mechanical instrumentation; pain; primary teeth; pulpectomy; root canal preparation | 0.64 | 27 | Dentistry | Dentistry | 2,024 |
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