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### Question: Do brainstem-vermis and brainstem-tentorium angles allow accurate categorization of fetal upward rotation of cerebellar vermis? ### Context: To evaluate the role of the brainstem-vermis (BV) and brainstem-tentorium (BT) angles in the differential diagnosis of upward rotation of the fetal cerebellar vermis... |
### Question: Does zoledronic acid induce significant and long-lasting modifications of circulating angiogenic factors in cancer patients? ### Context: The commercial availability of zoledronic acid, a third generation bisphosphonate, prompted us to evaluate the modifications in angiogenic cytokines levels after a sing... |
### Question: Is inflammatory cytokines in chronic heart failure : interleukin-8 associated with adverse outcome . Results from CORONA? ### Context: We investigated the ability of prototypical inflammatory cytokines to predict clinical outcomes in a large population of patients with chronic systolic heart failure (HF).... |
### Question: Are blood Cultures Useful in the Evaluation of Children with Uncomplicated Superficial Skin and Soft Tissue Infections? ### Context: Blood cultures (BCs) are commonly performed on children admitted to hospital for skin and soft tissue infections (SSTIs). In recent years, this practice has been questioned ... |
### Question: Do specific intraluminal nutrients alter mucosal blood flow during gut ischemia/reperfusion? ### Context: We have previously demonstrated in a rodent model the differential effects that specific intraluminal nutrients exert on gut ischemia/reperfusion (I/R) injury. Alanine was shown to amplify, whereas gl... |
### Question: Does standardized technique of laparoscopic pelvic and para-aortic lymphadenectomy in gynecologic cancer optimize the perioperative outcomes? ### Context: The main objective of this study is to illustrate the effectiveness and the safety of standardized technique of laparoscopic lymphadenectomy (LNE), new... |
### Question: Do serum monocyte chemotactic protein-1 concentrations distinguish patients with ankylosing spondylitis from patients with mechanical low back pain? ### Context: This study aimed to identify potential blood-derived biomarkers distinguishing patients with ankylosing spondylitis from those with mechanical l... |
### Question: Is femoral nerve `` sheath '' for inguinal paravascular lumbar plexus block found in human cadavers? ### Context: To determine if a femoral nerve sheath capable of conveying local anesthetic to the lumbar plexus and the obturator nerve exists in human cadavers.Injection of methylene blue dye into the femo... |
### Question: Is male scarcity associated with higher prevalence of premature gestation and low birth weight births across the United States? ### Context: Modern adverse birth outcomes may partially result from mechanisms evolved to evaluate environmental conditions and regulate maternal investment trade-offs. Male sca... |
### Question: Is liver Cirrhosis Independently Associated With 90-Day Mortality in ARDS Patients? ### Context: In a few studies, cirrhosis has been associated with increased mortality in patients with acute respiratory distress syndrome (ARDS). These studies were, however, conducted mostly before 2000. Over the last 15... |
### Question: Are circulating levels of DNA-histone complex and dsDNA independent prognostic factors of disseminated intravascular coagulation? ### Context: Neutrophils can be induced to release DNA combined with histones. The resulting neutrophil extracellular trap (NET) provides a scaffold for growing hemostatic plug... |
### Question: Modeling population pharmacokinetics of lidocaine: should cardiac output be included as a patient factor? ### Context: Inclusion of cardiac output and other physiologic parameters, in addition to or instead of, demographic variables might improve the population pharmacokinetic modeling of lidocaine.Thirty... |
### Question: Does the stress hormone adrenocorticotropin enhance sympathetic outflow to the muscle vascular bed in humans? ### Context: To examine the role of adrenocorticotropin in the regulation of the sympathetic outflow to the muscle vascular bed in healthy female humans.Eight healthy, nonsmoking female subjects (... |
### Question: Laparoscopic Distal Pancreatectomy in Benign or Premalignant Pancreatic Lesions: Is It Really More Cost-Effective than Open Approach? ### Context: Data regarding the quality of life in patients undergoing laparoscopic distal pancreatectomy are lacking and no studies have reported a real cost-effectiveness... |
### Question: Do minor changes in the hemagglutinin of influenza A ( H1N1 ) 2009 virus alter its antigenic properties? ### Context: The influenza A(H1N1)2009 virus has been the dominant type of influenza A virus in Finland during the 2009-2010 and 2010-2011 epidemic seasons. We analyzed the antigenic characteristics of... |
### Question: Is cytomegalovirus , and possibly Epstein-Barr virus , shedding in breast milk associated with HIV-1 transmission by breastfeeding? ### Context: Postnatal HIV-1 mother-to-child transmission (MTCT) occurs in spite of antiretroviral therapy. Co-infections in breast milk with cytomegalovirus (CMV) and Epstei... |
### Question: Is twist1 involved in trophoblast syncytialization by regulating GCM1? ### Context: The multinucleated syncytiotrophoblast (STB) is maintained and regenerated by the fusion of underlying cytotrophoblast cells (CTBs) and is responsible for a number of functions in the human placenta. Deficiencies in this s... |
### Question: Does fK506 increase permeability in rat intestine by inhibiting mitochondrial function? ### Context: Under normal physiological conditions, the intestine presents an adenosine triphosphate (ATP)-dependent barrier to luminal contents. Disruption of this barrier function can occur when cellular metabolism i... |
### Question: Does hepatic vascular endothelial growth factor regulate recruitment of rat liver sinusoidal endothelial cell progenitor cells? ### Context: After liver injury, bone marrow-derived liver sinusoidal endothelial cell progenitor cells (BM SPCs) repopulate the sinusoid as liver sinusoidal endothelial cells (L... |
### Question: Does affiliation of physician groups with one another produce higher quality primary care? ### Context: Recent reports have emphasized the importance of delivery systems in improving health care quality. However, few prior studies have assessed differences in primary care quality between physician groups ... |
### Question: Does spontaneous high systemic oxygen delivery increase survival rate in awake sheep during sustained endotoxemia? ### Context: To study the natural evolution of systemic oxygen delivery (Do2) and oxygen consumption (Vo2) in sheep infused with low or high doses of endotoxin.Prospective, controlled experim... |
### Question: Does overexpression of Cks1 increase the radiotherapy resistance of esophageal squamous cell carcinoma? ### Context: The Cks1 protein is a member of the highly conserved family of Cks/Suc1 proteins, which interact with Cdks, and was found to be an essential cofactor for efficient Skp2-dependent ubiquitina... |
### Question: Does coagulation-driven platelet activation reduce cholestatic liver injury and fibrosis in mice? ### Context: The coagulation cascade has been shown to participate in chronic liver injury and fibrosis, but the contribution of various thrombin targets, such as protease activated receptors (PARs) and fibri... |
### Question: Do beta1 and beta3 integrins cooperate to induce syndecan-4-containing cross-linked actin networks in human trabecular meshwork cells? ### Context: To characterize the molecular composition of cross-linked actin networks (CLANs) and the regulation of their formation by integrins in normal human trabecular... |
### Question: Does furosemide diminish ¹⁸F-fluoroethylcholine uptake in prostate cancer in vivo? ### Context: (18)F-Fluoroethylcholine ((18)F-FECh) is excreted via the urinary system with high activity accumulation in the urinary bladder. Furosemide and oral hydration can be administered concomitantly to reduce urinary... |
### Question: Is activation of UPR Signaling Pathway Associated With the Malignant Progression and Poor Prognosis in Prostate Cancer? ### Context: Currently, the role of UPR signaling in prostate cancer (PCa) is unclear. To evaluate the relationship between UPR signaling pathway and the prognosis of PCa, we explored th... |
### Question: Extended-spectrum betalactamases producing Escherichia coli: a new health-care associated infection threat? ### Context: Study the health-care associated infection risk due to Extended-Spectrum Betalactamases Producing Escherichia coli (ESBL Esc) isolated from diagnostic samples.Descriptive, longitudinal ... |
### Question: Does preeclampsia alter milk neurotrophins and long chain polyunsaturated fatty acids? ### Context: To examine the levels of breast milk neurotrophins 1.5, 3.5, and 6 months of lactation and long chain polyunsaturated fatty acids (LCPUFA) at day 3, 1.5, 2.5, 3.5 and 6 months of lactation in mothers with p... |
### Question: Does dNA-PKcs expression predict response to radiotherapy in prostate cancer? ### Context: Double-strand breaks, the most lethal DNA lesions induced by ionizing radiation, are mainly repaired by the nonhomologous end-joining system. The expression of the nonhomologous end-joining pathway has never been st... |
### Question: Length of prostate biopsy cores: does it impact cancer detection? ### Context: The detection of prostate carcinoma relies on adequate sampling. We aimed to evaluate whether core length is a significant biopsy parameter in the detection of cancer, especially in the low risk cancer category group.We retrosp... |
### Question: Is microalbuminuria more consistent in the presence of cardiovascular risk factors? ### Context: The use of microalbuminuria (MAU) to screen for cardiovascular and renal risk might be hampered by its intermittent character. This prospective observational study assessed traditional risk factors in presumed... |
### Question: Does acute administration of 17beta-estradiol reduce endothelin-1 release during pacing-induced ischemia? ### Context: To assess whether acute administration of 17beta-estradiol reduces pacing-induced cardiac release of endothelin-1 in female menopausal patients with coronary artery disease.Endothelin-1 i... |
### Question: Is cord blood insulin-like peptide 3 ( INSL3 ) but not testosterone reduced in idiopathic cryptorchidism? ### Context: Cryptorchidism, the most frequent congenital malformation in full-term male newborns, increases the risk of hypofertility and testicular cancer. Most cases remain idiopathic but epidemiol... |
### Question: Does the expression of murine cutaneous late phase reaction require both IgE antibodies and CD4 T cells? ### Context: Exposure of atopic patients to a specific allergen evokes an immediate response which is followed, in many cases, by a late phase reaction (LPR) some hours later. Here we have examined the... |
### Question: Does social context explain race disparities in obesity among women? ### Context: National data do not account for race differences in health risks resulting from racial segregation or the correlation between race and socioeconomic status. Therefore, these data may inaccurately attribute differences in ob... |
### Question: Does bone Regeneration be Promoted by Orally Administered Bovine Lactoferrin in a Rabbit Tibial Distraction Osteogenesis Model? ### Context: Lactoferrin, an iron-binding glycoprotein which belongs to the transferrin family, has been shown to promote bone growth. However, reports regarding effects of lacto... |
### Question: Does surface electrical stimulation perturbation context determine the presence of error reduction in swallowing hyolaryngeal kinematics? ### Context: Error-based learning (EBL) involves gradually reducing movement errors caused by a perturbation. When the perturbation has been unexpectedly removed, exagg... |
### Question: Is increasing complexity of algorithms the price for higher accuracy? ### Context: The algorithmic approach to guidelines has been introduced and promoted on a large scale since the 1970s. This study aims at comparing the performance of three algorithms for the management of chronic cough in patients with... |
### Question: Are iL-1beta-induced iNOS expression , NO release and loss in metabolic cell viability resistant to inhibitors of ceramide synthase and sphingomyelinase in INS 832/13 cells? ### Context: Emerging evidence indicates regulatory roles for ceramide in the metabolic dysfunction of the islet beta cell. Recently... |
### Question: Does prolonged hyperoxia preconditioning attenuate behavioral symptoms of 6-hydroxydopamine-induced Parkinsonism? ### Context: Several lines of evidences show that hyperoxia preconditioning provides neuronal protection against central nervous system ischemic damages. Common pathways including mitochondria... |
### Question: Does anxiety affect coping with chronic pain? ### Context: To evaluate whether symptoms of emotional distress related to pain affect patients' use of pain coping strategies. Relations between anxiety responses, as assessed by the Pain Anxiety Symptoms Scale, and coping strategies, as assessed by the Copin... |
### Question: Does pretreatment staging positron emission tomography/computed tomography in patients with inflammatory breast cancer influence radiation treatment field designs? ### Context: Positron emission tomography/computed tomography (PET/CT) is increasingly being utilized for staging of inflammatory breast cance... |
### Question: Does flaxseed reduce plasma cholesterol and atherosclerotic lesion formation in ovariectomized Golden Syrian hamsters? ### Context: Dietary modification contributes significantly in reducing cardiovascular disease (CVD) risk factors including lowering cholesterol and atherosclerosis. The purpose of this s... |
### Question: Does disruption of hemochromatosis protein and transferrin receptor 2 cause iron-induced liver injury in mice? ### Context: Mutations in hemochromatosis protein (HFE) or transferrin receptor 2 (TFR2) cause hereditary hemochromatosis (HH) by impeding production of the liver iron-regulatory hormone, hepcidi... |
### Question: Do hepatocytes undergo epithelial-mesenchymal transition in liver fibrosis in mice? ### Context: The origin of fibrogenic cells in liver fibrosis remains controversial. We assessed the emerging concept that hepatocytes contribute to production of extracellular matrix (ECM) in liver fibrosis through epithe... |
### Question: Do behavioral health services use among heads of homeless and housed poor families? ### Context: This study compares the use of and cost for behavioral health services among heads of homeless and housed poor families.Medicaid records for 59,135 heads of families receiving Temporary Assistance to Needy Fam... |
### Question: Revisiting endotracheal self-extubation in the surgical and trauma intensive care unit: Are they all fine? ### Context: Endotracheal self-extubation (ESE) is a serious health care concern. We designed this study to test our hypothesis that not all patients with ESE are successful in spontaneous breathing ... |
### Question: Does four-week multidisciplinary cardiac rehabilitation produce similar improvements in exercise capacity and quality of life to a 10-week program? ### Context: Cardiac rehabilitation (CR) is widely accepted as beneficial for patients with myocardial infarction (MI) and coronary artery bypass graft (CABG)... |
### Question: Does serum immunosuppressive acid protein predict lymph node metastases in patients with renal cell carcinoma? ### Context: To evaluate the usefulness of serum immunosuppressive acid protein (IAP) as a marker for lymph node metastases in patients with renal cell carcinoma.Serum IAP levels were studied in ... |
### Question: Does exogenous phosphatidylethanolamine induce apoptosis of human hepatoma HepG2 cells via the bcl-2/Bax pathway? ### Context: To investigate the signaling pathways implicated in phosphatidylethanolamine (PE)-induced apoptosis of human hepatoma HepG2 cells.Inhibitory effects of PE on human hepatoma HepG2 ... |
### Question: Altering the pattern of panretinal photocoagulation: could the visual field for driving be preserved? ### Context: To identify the area of retina required to provide the visual field for driving and to investigate whether the pattern of panretinal photocoagulation (PRP) for proliferative diabetic retinopa... |
### Question: Can Decision Support Help Patients With Spinal Stenosis Make a Treatment Choice? ### Context: A prospective, randomized study on patients with lumbar spinal stenosis who received a decision support intervention to facilitate their treatment choice.The aim of this study was to assess the impact of telephon... |
### Question: Does complement component C5a predict restenosis after superficial femoral artery balloon angioplasty? ### Context: To investigate whether balloon angioplasty of the superficial femoral artery (SFA) increases serum levels of C5a and whether C5a predicts risk of restenosis.C5a antigen was measured at basel... |
### Question: Does [ Parental anxiety increase pre-operative anxiety in the paediatric patient subjected to day surgery ]? ### Context: To evaluate the pre-operative anxiety associated with parental anxiety in children subjected to day surgery, by studying the parent-child behaviour and interaction in the surgical envi... |
### Question: Does resveratrol via activation of AMPK lower blood pressure in DOCA-salt hypertensive mice? ### Context: Resveratrol, a phytoalexin, is reported to activate AMP-activated protein kinase (AMPK) in vascular cells. Activation of AMPK induces vasorelaxation to lower blood pressure (BP). Whether resveratrol v... |
### Question: Does roxithromycin inhibit transforming growth factor-beta production by cultured human mesangial cells? ### Context: Transforming growth factor-beta (TGF-beta) plays an important role in progression of renal injury. However, few materials which inhibit TGF-beta have been known. Roxithromycin (ROX), macro... |
### Question: Are normally sighted, visually impaired, and blind pedestrians accurate and reliable at making street crossing decisions? ### Context: The purpose of this study is to measure the accuracy and reliability of normally sighted, visually impaired, and blind pedestrians at making street crossing decisions usin... |
### Question: Is early childhood stunting associated with lower developmental levels in the subsequent generation of children? ### Context: Linear growth retardation (stunting) is associated with lower adult cognition, educational attainment, and income. These effects, together with possible effects of stunting on birt... |
### Question: Can the organization of a binary mix be predicted from the surface energy, cohesion parameter and particle size of its components? ### Context: The aim of this study was to relate the organization of several binary mixes with three physical parameters (surface energy, cohesion parameter, and particle size... |
### Question: Requiring both avoidance and emotional numbing in DSM-V PTSD: will it help? ### Context: The proposed DSM-V criteria for posttraumatic stress disorder (PTSD) specifically require both active avoidance and emotional numbing symptoms for a diagnosis. In DSM-IV, since both are included in the same cluster, a... |
### Question: Do lactose-Free Milk or Soy-Based Formulas Improve Caregivers ' Distress or Perceptions of Difficult Infant Behavior? ### Context: The aim of the study was to test the hypothesis that caregiver-reported difficulties in infant behavior and caregivers' distress will significantly improve on lactose-free (LF... |
### Question: Does addition of long-distance heart procurement promote changes in heart transplant waiting list status? ### Context: Evaluate the addition of long-distance heart procurement on a heart transplant program and the status of heart transplant recipients waiting list.Between September 2006 and October 2012, ... |
### Question: Accuracy of real-time 3-dimensional echocardiography in the assessment of mitral prolapse. Is transesophageal echocardiography still mandatory? ### Context: Segmental analysis in mitral prolapse is important to decide the chances of valvular repair. Multiplane transesophageal echocardiography (TEE) is the... |
### Question: Is morning hypertension in chronic kidney disease sustained type , but not surge type? ### Context: We have shown that as renal function deteriorates, the circadian blood pressure (BP) rhythm shifts to a nondipper pattern and the duration until nocturnal BP decline [dipping time (DT)] is prolonged. We inv... |
### Question: Does miR-17-92 facilitate neuronal differentiation of transplanted neural stem/precursor cells under neuroinflammatory conditions? ### Context: Neural stem/precursor cells (NSCs) are of particular interest because of their potential application in cell therapy for brain damage. However, most brain injury ... |
### Question: Does next-generation sequencing of the Chrysanthemum nankingense ( Asteraceae ) transcriptome permit large-scale unigene assembly and SSR marker discovery? ### Context: Simple sequence repeats (SSRs) are ubiquitous in eukaryotic genomes. Chrysanthemum is one of the largest genera in the Asteraceae family.... |
### Question: Do myeloid-Derived Vascular Endothelial Growth Factor and Hypoxia-Inducible Factor Are Dispensable for Ocular Neovascularization -- Brief Report? ### Context: Ocular neovascularization (ONV) is a pathological feature of sight-threatening human diseases, such as diabetic retinopathy and age-related macular... |
### Question: Is long-term therapy with sorafenib associated with pancreatic atrophy? ### Context: Although the short-term adverse effects of sorafenib are well known, few data exist on long-term toxicity. The objective of the present study was to investigate the prevalence of pancreatic atrophy among a cohort of patie... |
### Question: Does dietary creatine supplementation affect some haematological indices , or indices of muscle damage and hepatic and renal function? ### Context: The use of creatine (Cr) as a nutritional supplement to aid athletic performance has gained widespread popularity among athletes. However, concerns have recen... |
### Question: Does an Immunohistochemical Survey of SNARE Proteins show Distinct Patterns of Expression in Hematolymphoid Neoplasia? ### Context: Five proteins from the soluble N-ethylmaleimide-sensitive factor activating protein receptor (SNARE) complex family were studied in normal hematopoietic cells in bone marrow;... |
### Question: Does multimodality imaging demonstrate trafficking of liposomes preferentially to ischemic myocardium? ### Context: Nanoparticles may serve as a promising means to deliver novel therapeutics to the myocardium following myocardial infarction. We sought to determine whether lipid-based liposomal nanoparticl... |
### Question: Does intensive rehabilitation permit early return to sport without compromising the clinical outcome after arthroscopic autologous chondrocyte implantation in highly competitive athletes? ### Context: Despite improvement in treatment for articular cartilage lesions, prolonged recovery still precludes earl... |
### Question: Is early proteinuria a strong indicator of donor renal lesions , ischemia-reperfusion injury and immunological aggression? ### Context: Early proteinuria is associated with reduced long-term graft survival. However, the determinants and mechanisms of proteinuria early after transplantation have not been i... |
### Question: Are high stable serum adiponectin levels associated with a better outcome in prevalent dialysis patients? ### Context: Our aim was to evaluate the prognostic value of 2 measurements of serum adiponectin levels for all-cause mortality and cardiovascular (CV) mortality in uremic patients.We analyzed 184 pat... |
### Question: Does aprotinin reduce blood loss in off-pump coronary artery bypass ( OPCAB ) surgery? ### Context: Effects of aprotinin in off-pump coronary artery bypass (OPCAB) surgery have not yet been described. This study analyses hemostasiologic changes and potential benefit in OPCAB patients treated with aprotini... |
### Question: Does protein kinase C theta play a fundamental role in different types of chronic colitis? ### Context: Dysregulated host/microbial interactions induce the development of colitis by activating deleterious acquired immune responses. Activation of CD4(+) T cells is mainly induced through signaling machinery... |
### Question: Is the T1799A BRAF mutation present in iris melanoma? ### Context: An activating mutation in exon 15 of the BRAF gene has been found in a high proportion of cutaneous pigmented lesions, but only in one case of uveal melanoma. Iris melanoma is the least common uveal melanoma and displays a less aggressive ... |
### Question: Is postural response of low-frequency component of heart rate variability an increased risk for mortality in patients with coronary artery disease? ### Context: We examined whether autonomic functions assessed by heart rate variability (HRV) during standardized head-up tilt testing (HUTT) predict risk for... |
### Question: Do most parents think receiving human papillomavirus vaccine would encourage sexual activity in their children? ### Context: To determine whether parents think receiving human papillomavirus (HPV) vaccine encourages sexual activity in their children.Parents of children 9 to 17 years old living in Georgia ... |
### Question: Hamstring anterior cruciate ligament reconstruction: is it necessary to sacrifice the gracilis? ### Context: The purpose of this study was to determine if there was a difference in the clinical results of anterior cruciate ligament (ACL) reconstruction when using the semitendinosus tendon (ST) alone versu... |
### Question: Do morphologic indicators predict the stage of chromatin condensation of human germinal vesicle oocytes recovered from stimulated cycles? ### Context: To assess germinal vesicles (GV) recovered from stimulated cycles by means of morphometric and morphologic examination (using contrast-phase and image anal... |
### Question: Do epileptic seizures predict outcome in patients with oligodendroglioma? ### Context: Many patients with an oligodendroglioma (OD) experience seizures, some of which become refractory to anti-epileptic drugs (AEDs). This study aims (1) to quantify the rate of seizures and medically refractory epilepsy in... |
### Question: Does medical students' preference of test format (computer-based vs. paper-based) have an influence on performance? ### Context: Computer-based examinations (CBE) ensure higher efficiency with respect to producibility and assessment compared to paper-based examinations (PBE). However, students often have ... |
### Question: Is pain-related fear associated with avoidance of spinal motion during recovery from low back pain? ### Context: A longitudinal assessment of the association between pain-related fear and joint motions in 36 participants with subacute low back pain.To determine how the psychologic construct of pain-relate... |
### Question: Does thrombin receptor levels in platelet concentrate during storage and their impact on platelet functionality? ### Context: Quality control of platelet (PLT) concentrates is challenging, due to PLT lesions, which are difficult to detect with routine methods. The search for reliable PLT lesion biomarkers... |
### Question: Are serum levels of angiopoietin-related growth factor increased in preeclampsia? ### Context: Preeclampsia is a serious complication in pregnancy with an increased future cardiovascular and metabolic risk for both mother and newborn. Recently, angiopoietin-related growth factor (AGF) was introduced as a ... |
### Question: Does digital gene expression tag profiling of bat digits provide robust candidates contributing to wing formation? ### Context: As the only truly flying mammals, bats use their unique wing - consisting of four elongated digits (digits II-V) connected by membranes - to power their flight. In addition to th... |
### Question: Does s-Nitrosylation of p47 ( phox ) enhance phosphorylation by casein kinase 2? ### Context: Leukocyte NADPH oxidase, which is active in neutrophils, is a membrane-bound enzyme that catalyzes the reduction of oxygen to O2(-) by using NADPH as an electron donor. Previously, we reported that casein kinase ... |
### Question: Are [ Parameters of oxygen uptake and carbon dioxide output ventilatory efficiency during exercise index of circulatory function in normal subjects ]? ### Context: To observe oxygen uptake efficiency plateau (OUEP, i.e.highest V˙O2/V˙E) and carbon dioxide output efficiency (lowest V˙E/V˙CO2) parameter cha... |
### Question: Does heart rate recovery predict clinical worsening in patients with pulmonary arterial hypertension? ### Context: Reduced heart rate recovery after exercise is associated with increased mortality in cardiopulmonary diseases.We sought to evaluate the association between heart rate recovery at 1 minute of ... |
### Question: Does short-term zinc supplementation attenuate Helicobacter felis-induced gastritis in the mouse? ### Context: Mucosal damage by H. pylori infection is mainly caused by neutrophils producing large quantities of reactive oxygen species (ROS). Metallothionein (MT) an intracellular, low-molecular, cysteine-r... |
### Question: Is music Beneficial for Awake Craniotomy Patients : A Qualitative Study? ### Context: Patients undergoing awake craniotomy may experience high levels of stress. Minimizing anxiety benefits patients and surgeons. Music has many therapeutic effects in altering human mood and emotion. Tonality of music as co... |
### Question: Does chronic angiotensin converting inhibition influence renal hemodynamic and function during cardiac surgery? ### Context: Treatment with angiotensin-converting enzyme (ACE) inhibitors affects the autoregulation of renal blood flow and glomerular filtration and provides renal protective effects. The pur... |
### Question: Is abnormal gastroesophageal flap valve highly associated with gastroesophageal reflux disease among subjects undergoing routine endoscopy in Taiwan? ### Context: Gastroesophageal flap valve (GEFV) grade predicts severe gastroesophageal reflux disease in Caucasians, but its role in other populations is un... |
### Question: Does liver ENPP1 protein increase with remission of type 2 diabetes after gastric bypass surgery? ### Context: Type 2 diabetes mellitus (T2DM) is a progressive disease resulting from increasing insulin resistance and reduced pancreatic β-cell insulin secretion. Ectonucleotide pyrophosphatase/phosphodieste... |
### Question: Do cancer incidence and mortality among beta-naphthylamine and benzidine dye workers in Moscow? ### Context: Cancer incidence and mortality were evaluated among 4581 aniline dye production workers in Moscow.A historical cohort was assembled and followed-up from 1 January 1975 to 31 December 1989. Moscow d... |
### Question: Does plasminogen activator-1 overexpression decrease experimental postthrombotic vein wall fibrosis by a non-vitronectin-dependent mechanism? ### Context: Factors associated with postthrombotic syndrome are known clinically, but the underlying cellular processes at the vein wall are not well delineated. P... |
### Question: Efficient funding: a path to improving Aboriginal healthcare in Australia? ### Context: To identify the factors that contribute to the under-resourcing of Aboriginal health and to explore the impact that funding arrangements have on the implementation of Aboriginal health policy.Qualitative study based on... |
### Question: Are ePS15R , TASP1 , and PRPF3 novel disease candidate genes targeted by HNF4alpha splice variants in hepatocellular carcinomas? ### Context: The orphan nuclear receptor HNF4alpha is a member of the hepatic transcription factor network. This protein plays a pivotal role in liver development and hepatocell... |
### Question: Are low serum mannose-binding lectin levels associated with inflammation and apoptosis in early surveillance allograft biopsies? ### Context: Mannose-binding lectin (MBL) is a protein of the innate immune system that participates in host defense and the tissue injury/repair process, enhancing the clearanc... |
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