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### Question: Does induction of autophagy improve hepatic lipid metabolism in glucose-6-phosphatase deficiency? ### Context: Glucose-6-phosphatase (G6Pase α, G6PC) deficiency, also known as von Gierke's disease or GSDIa, is the most common glycogen storage disorder. It is characterized by a decreased ability of the liv... |
### Question: Does additional surgical training increase participation in randomized controlled trials? ### Context: The prospective randomized controlled trial (PRCT) is agreeably the gold standard in reporting data on patient management. This study evaluates the impact of specialty training on the leadership, develop... |
### Question: Can health care quality indicators be transferred between countries? ### Context: To evaluate the transferability of primary care quality indicators by comparing indicators for common clinical problems developed using the same method in the UK and the USA.Quality indicators developed in the USA for a rang... |
### Question: Does uVB therapy increase 25 ( OH ) vitamin D syntheses in postmenopausal women with psoriasis? ### Context: Vitamin D3 is produced in the epidermis by ultraviolet (UV) radiation (290-315 nm) of 7-dehydrocholesterol. A similar range of 290-320 nm (broadband UVB) has been successfully used for years to tre... |
### Question: Does interaction of 8-hydroxyquinoline with soil environment mediate its ecological function? ### Context: Allelopathic functions of plant-released chemicals are often studied through growth bioassays assuming that these chemicals will directly impact plant growth. This overlooks the role of soil factors ... |
### Question: Does tc1 effector diversity show dissociated expression of granzyme B and interferon-gamma in HIV infection? ### Context: To examine antigen specific cytotoxic effector T cell diversity in HIV infected individuals.We used a panel of previously defined HLA class I-restricted HIV peptides to stimulate CD8 c... |
### Question: Is the Callander laryngoscope blade modification associated with a decreased risk of dental contact? ### Context: Dental damage may occur with laryngoscopy. The purpose of this study was twofold: to determine whether preoperative examination could predict the risk of contacting the teeth with the laryngos... |
### Question: Does low birth weight affect P-wave and QT dispersion in childhood? ### Context: The aim of our study is to investigate the effects of low birth weight (LBW) on atrial conduction and ventricular repolarization in children by using P-wave dispersion (Pw-d) and QT dispersion (QT-d) analyses. These effects h... |
### Question: Do schwann cells seeded in acellular nerve grafts improve functional recovery? ### Context: This study evaluated whether Schwann cells (SCs) from different nerve sources transplanted into cold-preserved acellular nerve grafts (CP-ANGs) would improve functional regeneration compared with nerve isografts.SC... |
### Question: Is paraoxonase-3 , a putative circulating antioxidant , systemically up-regulated in late gestation in the fetal rat , sheep , and human? ### Context: Surfactant is a successful therapeutic based on supplementing preterm infants with a substance that would normally have been up-regulated in late gestation... |
### Question: Is low serum IGF-1 a risk factor for cardiac allograft vasculopathy in cardiac transplant recipients? ### Context: Cardiac allograft vasculopathy (CAV) has an incidence of 43% at 8 years after heart transplantation with extremely limited treatment options and unclear pathogenesis. CAV constitutes a signif... |
### Question: Is quality of life less impaired in adults with congenital adrenal hyperplasia because of 21-hydroxylase deficiency than in patients with primary adrenal insufficiency? ### Context: Current replacement regimens fail to restore well-being in patients with primary adrenal insufficiency (PAI). Data on health... |
### Question: Does nutritional influence on growth and prevalence of anaemia in children during the war in Sarajevo? ### Context: To assess growth and prevalence of anaemia in hospitalised children during the war in Sarajevo.A random sample of children who were patients in the paediatric clinic over a period of six mon... |
### Question: Are head-to-head randomized trials mostly industry sponsored and almost always favor the industry sponsor? ### Context: To map the current status of head-to-head comparative randomized evidence and to assess whether funding may impact on trial design and results.From a 50% random sample of the randomized ... |
### Question: Do differences in height explain gender differences in the response to the oral glucose tolerance test- the AusDiab study? ### Context: To determine the extent of gender-related differences in the prevalence of glucose intolerance for the Australian population and whether body size may explain such differ... |
### Question: Do homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture? ### Context: Viperid snakebite envenomings are characterized by muscle necrosis and a deficient regenerative response.Homogenates from gastrocnemius muscles of mice injected with the venom of the ... |
### Question: Is cpG methylation and reduced expression of O6-methylguanine DNA methyltransferase associated with Helicobacter pylori infection? ### Context: The gastric epithelium genome undergoes extensive epigenetic alterations during Helicobacter pylori-induced gastritis. Expression of the gene encoding the DNA rep... |
### Question: Do iFN-γ and TNF-α induce a different modulation of interleukin-6 in systemic sclerosis fibroblasts compared to healthy controls? ### Context: To our knowledge, no previous study has evaluated the effect of interferon (IFN)-γ, tumour necrosis factor (TNF)-α, or their combination on the prototype proinflam... |
### Question: Does prostanoid EP4 receptor stimulation produce ocular hypotension by a mechanism that does not appear to involve uveoscleral outflow? ### Context: As part of a systematic elucidation of the pharmacology of prostaglandin's (PG) effects on intraocular pressure in the monkey, the prototypical selective pro... |
### Question: Is sPG10 a rare cause of spastic paraplegia in European families? ### Context: SPG10 is an autosomal dominant form of hereditary spastic paraplegia (HSP), which is caused by mutations in the neural kinesin heavy chain KIF5A gene, the neuronal motor of fast anterograde axonal transport. Only four mutations... |
### Question: Are mast cells required in the proliferation and remodeling phases of microdeformational wound therapy? ### Context: Mast cells are important in numerous inflammatory processes. They are also mechanosensitive and likely play an important role in wound healing. The authors hypothesized that mechanical alte... |
### Question: Is sanguinarine-induced apoptosis associated with an early and severe cellular glutathione depletion? ### Context: The quaternary benzophenanthridine alkaloid sanguinarine exhibits a broad range of activity, including cytotoxicity against various human tumour and normal cell lines. Here, we examined its p... |
### Question: Does cT coronary angiography predict the outcome of percutaneous coronary intervention of chronic total occlusion? ### Context: The success rate of percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) is relatively low. Further evaluation of CTO lesion with CT coronary angiography (C... |
### Question: Do traditional cardiovascular risk factors explain the minority of the variability in carotid plaque? ### Context: Subclinical atherosclerotic plaque is an important marker of increased vascular risk. Identifying factors underlying the variability in burden of atherosclerotic carotid plaque unexplained by... |
### Question: Is lymphadenectomy a prognostic marker in endometrioid adenocarcinoma of the human endometrium? ### Context: During surgery for endometrial cancer, a pelvic lymphadenectomy with or without para-aortic lymphadenectomy is performed at least in patients with risk factors (stage I, grading 2 and/or histologic... |
### Question: Is solid-surface vitrification an appropriate and convenient method for cryopreservation of isolated rat follicles? ### Context: Cryopreservation of isolated follicles may be a potential option to restore fertility in young women with cancer, because it can prevent the risks of cancer transmission. Severa... |
### Question: Does drugs and fall in older people in geriatric care settings? ### Context: Falls and their consequences constitute serious health problems in the older population. The aim was to study predisposing factors for falls among older people in geriatric care settings, focusing on drugs.This population-based s... |
### Question: Is short-latency afferent inhibition a poor predictor of individual susceptibility to rTMS-induced plasticity in the motor cortex of young and older adults? ### Context: Cortical plasticity, including long-term potentiation (LTP)-like plasticity, can be assessed non-invasively with repetitive transcranial... |
### Question: Do reactive oxygen species originating from mitochondria regulate the cardiac sodium channel? ### Context: Pyridine nucleotides regulate the cardiac Na(+) current (I(Na)) through generation of reactive oxygen species (ROS).We investigated the source of ROS induced by elevated NADH.In human embryonic kidne... |
### Question: Does hydrogen sulfide inhibit MPP ( + ) -induced apoptosis in PC12 cells? ### Context: Hydrogen sulfide (H2S) is a well-known cytotoxic gas. Recently it has been shown to protect neurons against oxidative stress caused by glutamate, hypochlorous acid (HOCl), and beta-amyloid. The aim of the present study ... |
### Question: Does insulin-like growth factor binding protein-3 lead to insulin resistance in adipocytes? ### Context: Transgenic mice overexpressing IGF binding protein-3 (IGFBP-3) have insulin resistance with reduced uptake of 2-deoxyglucose in muscle and adipose tissue.Our aim was to investigate the effects of IGFBP... |
### Question: Is delayed colo-anal anastomosis an alternative to prophylactic diverting stoma after total mesorectal excision for middle and low rectal carcinomas? ### Context: After total mesorectal excision (TME), a low colorectal or colo-anal anastomosis is usually performed. A prophylactic covering stoma is often u... |
### Question: Does vitamin D alter genes involved in follicular development and steroidogenesis in human cumulus granulosa cells? ### Context: Vitamin D deficiency is common among reproductive-aged women and has a role in female reproduction.This study evaluated the role of 1,25-dihydroxyvitamin D3 (vit D3) in ovarian ... |
### Question: Is fear of Movement Associated With Objective and Subjective Physical Activity Levels in Chronic Nonspecific Low Back Pain? ### Context: To assess the association of physical activity measures, derived with an accelerometer and a self-reported questionnaire, with fear of movement in patients with chronic ... |
### Question: Does glucagon-like peptide 1/glucagon receptor dual agonism reverse obesity in mice? ### Context: Oxyntomodulin (OXM) is a glucagon-like peptide 1 (GLP-1) receptor (GLP1R)/glucagon receptor (GCGR) dual agonist peptide that reduces body weight in obese subjects through increased energy expenditure and decr... |
### Question: Does simvastatin reduce neointimal thickening in low-density lipoprotein receptor-deficient mice after experimental angioplasty without changing plasma lipids? ### Context: Statins exert antiinflammatory and antiproliferative actions independent of cholesterol lowering. To determine whether these actions ... |
### Question: Does long segment ileal transposition lead to early amelioration of glucose control in the diabetic obese Zucker rat? ### Context: Fast delivery of food to the terminal ileum is thought to be pathophysiologically responsible for type 2 diabetes remission after obesity surgery. Imitating this effect, ileal... |
### Question: Does resveratrol preserve myocardial function and perfusion in remote nonischemic myocardium in a swine model of metabolic syndrome? ### Context: Resveratrol has been shown to reverse some of the detrimental effects of metabolic syndrome (MetS). We sought to define the impact of supplemental resveratrol o... |
### Question: Does drug-induced deactivation of inhibitory networks predict pathological gambling in PD? ### Context: Some patients with Parkinson disease (PD) develop pathological gambling when treated with dopamine agonists (DAs). However, little is known about DA-induced changes in neuronal networks that may underpi... |
### Question: Psoriasis: is it the tip of the iceberg for the quality of life of patients and their families? ### Context: To evaluate the impact of psoriasis on patients' and their relatives' quality of life (QoL).Eighty patients with their accompanying family members were included in the study. For measuring health r... |
### Question: Does norepinephrine-induced vasoconstriction result in decreased blood volume in dialysis patients? ### Context: Hypotension during haemodialysis results from an inadequate cardiovascular response to ultrafiltration-induced hypovolaemia. It has been suggested that plasma volume could be increased as a res... |
### Question: Do class A dioscorins of various yam species suppress ovalbumin-induced allergic reactions? ### Context: Dioscorins, the primary storage proteins in yam tubers, of different species exhibited varying immunomodulatory activities in mice. We inferred that this might be attributed to the various isoforms in ... |
### Question: Does serotonin ( 5-hydroxytryptamine ) transporter inhibition cause bone loss in adult mice independently of estrogen deficiency? ### Context: Selective serotonin reuptake inhibitors (SSRIs) treat depression by antagonizing the serotonin (5-hydroxytryptamine) transporter (5-HTT). These drugs may also have... |
### Question: Are health care providers still smoking? ### Context: Smoking by health care professionals poses a barrier to interventions with patients. This study reports smoking status changes among health care professionals using the Tobacco Use Supplement-Current Population Surveys (TUS-CPS).TUS-CPS self-reported s... |
### Question: Surgical treatment of familial adenomatous polyposis: ileorectal anastomosis or restorative proctolectomy? ### Context: Controversy regarding the best operative choice for familial adenomatous polyposis lays between the morbidity of restorative proctocolectomy and the supposed mortality due to rectal canc... |
### Question: Is serum Surfactant Protein D Associated with Atherosclerosis of the Carotid Artery in Patients on Maintenance Hemodialysis? ### Context: Surfactant protein-D (SP-D) is an inflammatory modulator that has been associated with cardiovascular disease-related mortality, estimated glomerular filtration rate, a... |
### Question: Does application of HIV-1 genotypic-resistance testing prevent the evolution of further resistance mutations in heavily pretreated patients? ### Context: Resistance-associated mutations in HIV-1 evolve even under highly active antiretroviral therapy.To evaluate the clinical efficacy of genotypic-resistanc... |
### Question: Does male adiposity impair clinical pregnancy rate by in vitro fertilization without affecting day 3 embryo quality? ### Context: Male adiposity is detrimental for achieving clinical pregnancy rate (CPR) following assisted reproductive technologies (ART). The hypothesis that the association of male adipos... |
### Question: Can experts in acetabular fracture care determine hip stability after posterior wall fractures using plain radiographs and computed tomography? ### Context: Hip stability status after a posterior wall acetabular fracture involving 20%-50% of the posterior wall is difficult to determine. However, noted exp... |
### Question: Does size matter? ### Context: Excess pulmonary to systemic blood flow ratio (Qp/Qs) correlates with hemodynamic instability and mortality after modified Norwood operation. Studies suggest that maximal oxygen delivery occurs at a Qp/Qs of around 1. The use of a rather small modified Blalock-Taussig shunt ... |
### Question: Does health behaviors among people with epilepsy -- result from the 2010 National Health Interview Survey? ### Context: This study aimed to estimate and compare the prevalence of selected health behavior-alcohol use, cigarette smoking, physical activity, and sufficient sleep-between people with and withou... |
### Question: Is an endothelial nitric oxide synthase gene mutation a risk factor in the origin of intraventricular hemorrhage? ### Context: Studies have shown decreased levels of nitric oxide (NO), the product of endothelial NO synthase (eNOS) gene activity, in infants with respiratory conditions and intraventricular ... |
### Question: Does shear stress-induced activation of the AMP-activated protein kinase regulate FoxO1a and angiopoietin-2 in endothelial cells? ### Context: Phosphorylation of forkhead box O (FoxO) transcription factors induces their nuclear exclusion and proteosomal degradation. Here, we investigated the effect of flu... |
### Question: Does the association between anomalous self-experience and suicidality in first-episode schizophrenia seem mediated by depression? ### Context: A recent hypothesis is that suicidality in schizophrenia may be linked to the patients' altered basic self-awareness or sense of self, termed self-disorders (SDs)... |
### Question: Do hydroxyurea and trimidox enhance the radiation effect in human pancreatic adenocarcinoma cells? ### Context: Pancreatic cancer remains the most lethal of all common human malignancies with a 5-year survival rate of lower than 5%. Adjuvant and neoadjuvant preoperative and postoperative chemo-radiotherap... |
### Question: Is increased expression of vascular endothelial growth factor-C and nuclear CXCR4 in hepatocellular carcinoma correlated with lymph node metastasis and poor outcome? ### Context: Lymph node metastasis (LNM) is a chief cause of morbidity and mortality in patients with hepatocellular carcinoma (HCC) after h... |
### Question: Are wound complications after a kidney transplant more common with modern immunosuppression? ### Context: The most common surgical complication after a kidney transplant is likely related to the wound. The purpose of this analysis was to determine the incidence of, and risk factors for, wound complication... |
### Question: Is unsedated colonoscopy introduced to ensure access acceptable to a subgroup of veterans? ### Context: Nurses for monitoring and recovery are required for sedated colonoscopy. A nursing shortage necessitated discontinuation of sedated colonoscopy at a VA academic training program.Elements of a case serie... |
### Question: Does the type of urinary diversion after radical cystectomy significantly impact on the patient 's quality of life? ### Context: In this study, we used a previously well-validated survey to assess the impact of different forms of urinary diversion on overall quality of life in patients with bladder cancer... |
### Question: Does cerebral hypoxia-ischemia stimulate cytokine gene expression in perinatal rats? ### Context: We tested the hypothesis that cerebral hypoxia-ischemia selectively stimulates interleukin-1 beta (IL-1 beta) and tumor necrosis factor-alpha (TNF-alpha) gene expression in brain regions susceptible to irreve... |
### Question: Spontaneous tegmen defect and semicircular canal dehiscence: same etiopathogenic entity? ### Context: To describe the clinical and radiologic features of associated spontaneous tegmen defects (STDs) with semicircular canal dehiscences (SCCDs) and to postulate a novel etiopathogenic hypothesis of these pa... |
### Question: Is ultrasonographic evidence that bedrest after embryo transfer useless? ### Context: To demonstrate the effect of immediate ambulation after embryo transfer on the intrauterine location of the transfer content.Prospective observational randomized controlled study.Fifty-seven patients (47.5%) had one air ... |
### Question: Procollagen propeptides: serum markers for atrial fibrosis? ### Context: Atrial fibrosis and its spatial heterogeneity are regarded as a substrate for the perpetuation of atrial arrhythmias. During collagen synthesis and degradation, collagen propeptides and telopeptides are released into the blood. This ... |
### Question: Intrauterine growth restriction at term: induction or spontaneous labour? ### Context: To test the hypothesis that in pregnancies with a clinically suspected growth restricted foetus at term, induction of labour is as safe as expectant management, and does not lead to increased obstetrical interventions o... |
### Question: Does long-term lactation protect premenopausal women against hypertension risk? ### Context: Little is known about the long-term effect of lactation on maternal cardiovascular health except for a few animal or human experimental studies. The objective of this study was to examine the effects of lactation ... |
### Question: Does loss of heterozygosity in critical genome regions predict a local relapse in patients after laryngectomy? ### Context: Patients, who had an upper aerodigestive tract malignancy, have a high incidence of succeeding tumor development. This has been attributed to the role of "field cancerization" in car... |
### Question: Do estimating the Preoperative Corneal Power With Scheimpflug Imaging in Eyes That Have Undergone Myopic LASIK? ### Context: To investigate whether the Estimated Pre-Refractive SimK accurately predicts the preoperative corneal power (K) in eyes with previous myopic femtosecond laser-assisted LASIK (FS-LAS... |
### Question: Does surface coating to improve the metal-cement bonding in cemented femur stem? ### Context: Hydrolytic debonding of the metal-cement interface is one of the main reasons for aseptic loosening in cemented hip arthroplasty.BiContact femur stems (CoCrMo-/TiAl6V4-alloy) were coated by a silica/silane interl... |
### Question: Does forskolin induce myosin light chain dephosphorylation in bovine trabecular meshwork cells? ### Context: Enhanced contractility of the actin cytoskeleton in trabecular meshwork (TM) cells is implicated in increased resistance to aqueous humor outflow. In this study, we have investigated effects of for... |
### Question: Does vaginal anti-incontinence surgery affect sexual satisfaction? ### Context: To evaluate the sexual satisfaction rates of women who underwent tension-free vaginal tape (TVT) procedure for stress urinary incontinence and compare it with the results of Burch-colposuspension.A self-administered questionna... |
### Question: Does early effective suppression of inflammation in rheumatoid arthritis reduce radiographic progression? ### Context: To evaluate the effect of early 'aggressive' drug treatment on radiographic progression in patients with recent-onset rheumatoid arthritis (RA), compared to conventional stepwise increasi... |
### Question: Preeclampsia: immunologic alteration of Nitabuch's membrane? ### Context: To determine if preeclampsia is an immunologic disease process consistent with a host-vs.-graft reaction by examining differences in immunoglobulin deposition at the maternal fetal interface (Nitabuch's layer) in preeclamptic patien... |
### Question: Can practice guidelines be transported effectively to different settings? ### Context: Although clinical guidelines have become increasingly popular as a means to reduce variation in care, increase efficiency, and improve patient outcomes, little is known about their effectiveness when they are transporte... |
### Question: Does the presence of one feature of borderline personality disorder have clinical significance? ### Context: In the draft proposal for DSM-5, the Work Group for Personality and Personality Disorders recommended that dimensional ratings of personality disorders replace DSM-IV's categorical approach toward ... |
### Question: Does metastatic Lymph Node Ratio of Central Neck Compartment have Predictive Values for Locoregional Recurrence in Papillary Thyroid Microcarcinoma? ### Context: This study aimed to evaluate the significance of metastatic lymph node ratio (the ratio between the metastatic lymph node and the harvested lymp... |
### Question: Does bath Concentration of Anionic Contrast Agents Affect Their Diffusion and Distribution in Articular Cartilage In Vitro? ### Context: Differences in contrast agent diffusion reflect changes in composition and structure of articular cartilage. However, in clinical application the contrast agent concentr... |
### Question: Are human enterovirus and rhinovirus infections associated with otitis media in a prospective birth cohort study? ### Context: Human enteroviruses (HEVs) and rhinoviruses (HRVs) have been linked to acute otitis media (AOM).The present study evaluates the aforementioned association in a birth cohort settin... |
### Question: Are patient-reported and physician-estimated adherence to HAART : social and clinic center-related factors associated with discordance? ### Context: To evaluate the rate of discordance between patients and physicians on adherence to highly active antiretroviral therapy (HAART) and identify factors related... |
### Question: Is estrogen induction of smooth muscle differentiation of human prostatic stromal cells mediated by transforming growth factor-beta? ### Context: The differentiation of prostatic fibroblasts into smooth muscle cells is regarded as the key step in the development of periurethral stromal nodules. Intraprost... |
### Question: Do physicians overestimate effects of acupuncture treatment? ### Context: Physicians' ratings about their patients' pain prove to be invalid compared to patients' ratings. This is especially true if pain rating acts as an indicator for therapy outcome. The aim of this study was to compare physicians' and ... |
### Question: Do ced-4 and proto-oncogene tfg-1 antagonistically regulate cell size and apoptosis in C. elegans? ### Context: Cell-size-control systems, coupled with apoptotic- and cell-proliferation-regulatory mechanisms, determine the overall dimensions of organs and organisms, and their dysregulation can lead to tum... |
### Question: Are platelets a possible regulator of human endometrial re-epithelialization during menstruation? ### Context: The human endometrium periodically breaks down and regenerates. As platelets have been reported to contribute to the tissue remodeling process, we examined the possible involvement of platelets i... |
### Question: Do synthesis and characterization of wollastonite glass-ceramics for dental implant applications? ### Context: To synthesize a glass-ceramic (GC) that is suitable for non-metallic one-piece dental implant application.Three glasses in a SiO2-Al2O3-CaO-CaF2-K2O-B2O3-P2O5-CeO2-Y2O3 system were produced by we... |
### Question: Does vitamin E have a dual effect of anti-inflammatory and antioxidant activities in acetic acid-induced ulcerative colitis in rats? ### Context: Increased free radical production, decreased antioxidant capacity and excessive inflammation are well-known features in the pathogenesis of inflammatory bowel d... |
### Question: Do neck kinematics correlate with pain intensity, neck disability or with fear of motion? ### Context: This study aimed to investigate the relationship between cervical kinematics and subjective measures, including pain intensity, disability, and fear of motion.Twenty-five patients (19 females, 6 males; m... |
### Question: Are pheochromocytomas detected by biochemical screening in predisposed subjects associated with lower prevalence of clinical and biochemical manifestations and smaller tumors than pheochromocytomas detected by signs and symptoms? ### Context: Sporadic pheochromocytomas are detected by clinical signs and s... |
### Question: Does laparoscopic surgery inhibit the proliferation and metastasis of cervical cancer cells? ### Context: The present study is to investigate the effect of laparoscopic surgery on the proliferation and metastasis of cervical cancer cells.A total of 40 patients with phase I squamous cell carcinoma of the c... |
### Question: Is the influenza vaccination rate of elderly patients affected by raising the vaccination rate of the staff at their primary health care clinics? ### Context: Influenza vaccination of community-dwelling elderly is widely recommended. Observational studies have shown a strong association between physicians... |
### Question: Do long-term outcome in 44 horses with stifle lameness after arthroscopic exploration and debridement? ### Context: To (1) examine the outcome in horses with osteoarthritis or intra-articular soft tissue injuries of the stifle after arthroscopic exploration and debridement and (2) to determine any imaging... |
### Question: Is markers of susceptibility to acute rheumatic fever : the B-cell antigen D8/17 robust as a marker in South Africa? ### Context: Acute rheumatic fever and its chronic sequelae, rheumatic cardiac disease, and neuropsychiatric movement disorders, remain major public health problems in South Africa. Early i... |
### Question: Can the neurovascular compression volume of the trigeminal nerve on magnetic resonance cisternography predict the success of local anesthetic block after initial treatment by the carbamazepine? ### Context: Whether NVC volume on magnetic resonance (MR) cisternography might be related to the success of loc... |
### Question: Does immunosuppressant FK506 decrease the intracellular magnesium in the human osteoblast cell by inhibiting the ERK1/2 pathway? ### Context: Previous studies reported that FK506 influences bone mineralizing and hypomagnesemia, and also has immune modifying properties. This study examined whether or not t... |
### Question: Is There a Safe Lipoaspirate Volume? ### Context: No concrete data exist to support a specific volume at which liposuction becomes unsafe; surgeons rely on their own estimates, professional organization advisories, or institutional or government-imposed restrictions. This study represents the first attemp... |
### Question: Is a body mass index of 23 kg/m² a reliable marker of protein-energy wasting in hemodialysis patients? ### Context: To evaluate the body composition and inflammatory status in patients on hemodialysis (HD) according to the cutoff of 23 kg/m² for the body mass index (BMI).Forty-seven patients (30 men, 11 d... |
### Question: Is low number of omental preadipocytes with high leptin and low adiponectin secretion associated with high fasting plasma glucose levels in obese subjects? ### Context: This study investigates whether fasting plasma glucose (FPG) levels in obese subjects are associated with the number of preadipocytes and... |
### Question: Does interaction Between Gastric Carcinoma Cells and Neural Cells promote Perineural Invasion by a Pathway Involving VCAM1? ### Context: Perineural invasion (PNI) is one of the important routes for local spread of gastric carcinoma associated with poor prognosis. However, the exact cellular characteristic... |
### Question: Are nutrition and inflammation serum biomarkers associated with 12-week mortality among malnourished adults initiating antiretroviral therapy in Zambia? ### Context: A low body mass index (BMI) at antiretroviral therapy (ART) initiation is a strong predictor of mortality among HIV-infected adults in resou... |
### Question: Are plasma acylated ghrelin levels higher in patients with chronic atrophic gastritis? ### Context: Ghrelin is mainly produced by the endocrine cells of the gastric oxyntic mucosa. For this reason we decided to investigate the modification of the circulating levels not only of total but also of acylated g... |
### Question: Does gender affect response to a brief clinic-based smoking intervention? ### Context: Although recent reviews suggest few gender differences in smoking-cessation outcomes, it is important to establish whether gender differences exist in response to the brief interventions increasingly recommended as part... |
### Question: CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated? ### Context: In chronic pancreatitis (CP), alterations in several genes have so far been described, but only small cohorts have been extensively investigated for all predisposing genes.660 patients wi... |
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