document_id
int64
185
2.68k
context
stringlengths
2.88k
70.8k
question
stringlengths
11
194
id
int64
225
5.32k
answer
stringlengths
1
933
answer_start
int64
157
69k
1,583
A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618839/ SHA: ee1b5a9618dcc4080ed100486cedd0969e80fa4d Authors: Porten, Klaudia; Rissland, Jürgen; Tigges, Almira; Broll, Susanne; Hopp, Wilfried; Lunemann, Mechthild; van Treeck, Ulrich; ...
What was the median seropresence of C. burnetti in sheep flocks not linked to human outbreaks?
5,202
1%
28,273
1,583
A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618839/ SHA: ee1b5a9618dcc4080ed100486cedd0969e80fa4d Authors: Porten, Klaudia; Rissland, Jürgen; Tigges, Almira; Broll, Susanne; Hopp, Wilfried; Lunemann, Mechthild; van Treeck, Ulrich; ...
What important risk factors to infection were found during the second case-controlled study?
5,203
close proximity to the ewe and duration of exposure
23,543
1,583
A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618839/ SHA: ee1b5a9618dcc4080ed100486cedd0969e80fa4d Authors: Porten, Klaudia; Rissland, Jürgen; Tigges, Almira; Broll, Susanne; Hopp, Wilfried; Lunemann, Mechthild; van Treeck, Ulrich; ...
What was the interquartile range of the incubation period?
5,204
16 to 24 days
22,586
1,583
A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618839/ SHA: ee1b5a9618dcc4080ed100486cedd0969e80fa4d Authors: Porten, Klaudia; Rissland, Jürgen; Tigges, Almira; Broll, Susanne; Hopp, Wilfried; Lunemann, Mechthild; van Treeck, Ulrich; ...
How many controls were used in the second case study?
5,205
36
18,033
1,583
A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618839/ SHA: ee1b5a9618dcc4080ed100486cedd0969e80fa4d Authors: Porten, Klaudia; Rissland, Jürgen; Tigges, Almira; Broll, Susanne; Hopp, Wilfried; Lunemann, Mechthild; van Treeck, Ulrich; ...
What public event was linked with the outbreak?
5,206
farmers' market
14,811
1,583
A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618839/ SHA: ee1b5a9618dcc4080ed100486cedd0969e80fa4d Authors: Porten, Klaudia; Rissland, Jürgen; Tigges, Almira; Broll, Susanne; Hopp, Wilfried; Lunemann, Mechthild; van Treeck, Ulrich; ...
What causes Q fever?
5,207
Coxiella burnetii (C. burnetii)
2,378
1,583
A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618839/ SHA: ee1b5a9618dcc4080ed100486cedd0969e80fa4d Authors: Porten, Klaudia; Rissland, Jürgen; Tigges, Almira; Broll, Susanne; Hopp, Wilfried; Lunemann, Mechthild; van Treeck, Ulrich; ...
What is Coxiella burnetii?
5,208
small, gram-negative obligate intracellular bacterium
2,413
1,583
A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618839/ SHA: ee1b5a9618dcc4080ed100486cedd0969e80fa4d Authors: Porten, Klaudia; Rissland, Jürgen; Tigges, Almira; Broll, Susanne; Hopp, Wilfried; Lunemann, Mechthild; van Treeck, Ulrich; ...
What is the primary reservoir for Coxiella burnetii?
5,209
sheep, goat and cattle
2,634
1,583
A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1618839/ SHA: ee1b5a9618dcc4080ed100486cedd0969e80fa4d Authors: Porten, Klaudia; Rissland, Jürgen; Tigges, Almira; Broll, Susanne; Hopp, Wilfried; Lunemann, Mechthild; van Treeck, Ulrich; ...
How are humans typically infected with Coxiella burnetii?
5,210
inhalation of contaminated aerosols from parturient fluids, placenta or wool
2,913
1,588
Prediction of lncRNA-protein interactions using HeteSim scores based on heterogeneous networks https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473862/ SHA: f4f9ea9e0aeb74d3601ee316b84292638c59cc53 Authors: Xiao, Yun; Zhang, Jingpu; Deng, Lei Date: 2017-06-16 DOI: 10.1038/s41598-017-03986-1 License: cc-by Abstract: Ma...
What are critical to regulate cellular biological processes?
3,687
long non-coding RNAs
354
1,588
Prediction of lncRNA-protein interactions using HeteSim scores based on heterogeneous networks https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473862/ SHA: f4f9ea9e0aeb74d3601ee316b84292638c59cc53 Authors: Xiao, Yun; Zhang, Jingpu; Deng, Lei Date: 2017-06-16 DOI: 10.1038/s41598-017-03986-1 License: cc-by Abstract: Ma...
How is the HeteSim measured used?
3,688
calculate the relatedness of objects with the same or different types
16,718
1,588
Prediction of lncRNA-protein interactions using HeteSim scores based on heterogeneous networks https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473862/ SHA: f4f9ea9e0aeb74d3601ee316b84292638c59cc53 Authors: Xiao, Yun; Zhang, Jingpu; Deng, Lei Date: 2017-06-16 DOI: 10.1038/s41598-017-03986-1 License: cc-by Abstract: Ma...
What kind of data is included in the STRING database?
3,689
weighted protein interactions
16,316
1,588
Prediction of lncRNA-protein interactions using HeteSim scores based on heterogeneous networks https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473862/ SHA: f4f9ea9e0aeb74d3601ee316b84292638c59cc53 Authors: Xiao, Yun; Zhang, Jingpu; Deng, Lei Date: 2017-06-16 DOI: 10.1038/s41598-017-03986-1 License: cc-by Abstract: Ma...
What is the function of MALAT1?
3,690
regulates cell cycle and survival
11,065
1,554
Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444036/ SHA: ee3cc22161595e877450737882a52950fd179672 Authors: Gal-Or, Orly; Priel, Ethan; Rosenblatt, Irit; Shulman, Shiri; Kramer, Michal Date: 2017-05-11 DOI: 10.1155/2017/7535320 Licen...
What is multiple evanescent white dot syndrome?
581
a rare, sudden onset of unilateral chorioretinopathy
1,882
1,554
Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444036/ SHA: ee3cc22161595e877450737882a52950fd179672 Authors: Gal-Or, Orly; Priel, Ethan; Rosenblatt, Irit; Shulman, Shiri; Kramer, Michal Date: 2017-05-11 DOI: 10.1155/2017/7535320 Licen...
What precedes about half of the reported cases of MEWDS?
582
flu-like illness
2,345
1,554
Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444036/ SHA: ee3cc22161595e877450737882a52950fd179672 Authors: Gal-Or, Orly; Priel, Ethan; Rosenblatt, Irit; Shulman, Shiri; Kramer, Michal Date: 2017-05-11 DOI: 10.1155/2017/7535320 Licen...
What types of viruses can be diagnosed through serological testing?
583
herpes simplex virus (HSV) I-II, varicella zoster virus (VZV), West Nile virus, coxsackievirus, echovirus (subgroup of enterovirus), and corona virus
5,843
1,554
Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444036/ SHA: ee3cc22161595e877450737882a52950fd179672 Authors: Gal-Or, Orly; Priel, Ethan; Rosenblatt, Irit; Shulman, Shiri; Kramer, Michal Date: 2017-05-11 DOI: 10.1155/2017/7535320 Licen...
What type of clinical test can differentiate multiple evanescent white dot syndrome (MEWDS) from optic neuritis?
584
multimodal imaging
13,925
1,568
Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/ SHA: f2e835d2cde5f42054dbd0c20d4060721135c518 Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi Date: 2017-12-07 DOI: 10.1186/s13104-017-3063-1 License:...
What were the most common viruses sampled from nasal swabs in Ilorin, Nigeria
1,597
Parainfluenza virus 4, respiratory syncytial virus B and enterovirus
1,041
1,568
Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/ SHA: f2e835d2cde5f42054dbd0c20d4060721135c518 Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi Date: 2017-12-07 DOI: 10.1186/s13104-017-3063-1 License:...
What was the most common virus detected in community members in this sample?
1,598
Coronavirus OC43
1,285
1,568
Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/ SHA: f2e835d2cde5f42054dbd0c20d4060721135c518 Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi Date: 2017-12-07 DOI: 10.1186/s13104-017-3063-1 License:...
How bad is the burden of disease in developing countries?
1,599
2-5 times higher than in developed countries
2,063
1,568
Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/ SHA: f2e835d2cde5f42054dbd0c20d4060721135c518 Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi Date: 2017-12-07 DOI: 10.1186/s13104-017-3063-1 License:...
Where do the majority of all infectious disease outbreaks happen?
1,600
Africa
2,552
1,568
Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/ SHA: f2e835d2cde5f42054dbd0c20d4060721135c518 Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi Date: 2017-12-07 DOI: 10.1186/s13104-017-3063-1 License:...
What are some risk factors for countries to experience a high prevalence of Acute Respiratory Infections?
1,601
age, sex, overcrowding, nutritional status, socio-economic status, and where study of ARIs is currently limited
3,037
1,568
Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/ SHA: f2e835d2cde5f42054dbd0c20d4060721135c518 Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi Date: 2017-12-07 DOI: 10.1186/s13104-017-3063-1 License:...
What symptoms are associated with acute respiratory infections?
1,602
sore throat, fever, couch, running nose, vomiting, body ache, leg pain, nausea, chills, shortness of breath
6,502
1,568
Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/ SHA: f2e835d2cde5f42054dbd0c20d4060721135c518 Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi Date: 2017-12-07 DOI: 10.1186/s13104-017-3063-1 License:...
What was the most common virus detected in community samples in Ilorin, Nigeria?
1,603
Coronavirus OC43
10,380
1,568
Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/ SHA: f2e835d2cde5f42054dbd0c20d4060721135c518 Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi Date: 2017-12-07 DOI: 10.1186/s13104-017-3063-1 License:...
What was the prevalence of Coronavirus OC43 in community samples in Ilorin, Nigeria?
1,604
13.3% (95% CI 6.9-23.6%)
10,425
1,568
Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/ SHA: f2e835d2cde5f42054dbd0c20d4060721135c518 Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi Date: 2017-12-07 DOI: 10.1186/s13104-017-3063-1 License:...
What was the prevalence of Coronavirus OC 229 E/NL63 in clinical subjects in Ilorin, Nigeria?
1,605
12.5%
10,584
1,568
Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/ SHA: f2e835d2cde5f42054dbd0c20d4060721135c518 Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi Date: 2017-12-07 DOI: 10.1186/s13104-017-3063-1 License:...
What was the difference between community and clinic cases of acute respiratory infections?
1,606
increased severity of illness in the clinical sample
11,074
1,568
Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719735/ SHA: f2e835d2cde5f42054dbd0c20d4060721135c518 Authors: Kolawole, Olatunji; Oguntoye, Michael; Dam, Tina; Chunara, Rumi Date: 2017-12-07 DOI: 10.1186/s13104-017-3063-1 License:...
How can countries enhance public health surveillance?
1,607
active community surveillance
13,076
1,566
Aetiology of Acute Respiratory Tract Infections in Hospitalised Children in Cyprus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720120/ SHA: efd27ff0ac04dd60838266386aaebb5df80f4fa9 Authors: Richter, Jan; Panayiotou, Christakis; Tryfonos, Christina; Koptides, Dana; Koliou, Maria; Kalogirou, Nikolas; Georgiou, Eleni...
Why do respiratory tract infections pose major public health problems?
1,608
world-wide occurrence, ease of transmission and considerable morbidity and mortality effecting people of all ages
1,878
1,566
Aetiology of Acute Respiratory Tract Infections in Hospitalised Children in Cyprus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720120/ SHA: efd27ff0ac04dd60838266386aaebb5df80f4fa9 Authors: Richter, Jan; Panayiotou, Christakis; Tryfonos, Christina; Koptides, Dana; Koliou, Maria; Kalogirou, Nikolas; Georgiou, Eleni...
How much of a greater risk are children than adults to viral infections?
1,609
two to three times more frequently
2,026
1,566
Aetiology of Acute Respiratory Tract Infections in Hospitalised Children in Cyprus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720120/ SHA: efd27ff0ac04dd60838266386aaebb5df80f4fa9 Authors: Richter, Jan; Panayiotou, Christakis; Tryfonos, Christina; Koptides, Dana; Koliou, Maria; Kalogirou, Nikolas; Georgiou, Eleni...
What is the most common infection in childhood?
1,610
acute RTI
2,079
1,566
Aetiology of Acute Respiratory Tract Infections in Hospitalised Children in Cyprus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720120/ SHA: efd27ff0ac04dd60838266386aaebb5df80f4fa9 Authors: Richter, Jan; Panayiotou, Christakis; Tryfonos, Christina; Koptides, Dana; Koliou, Maria; Kalogirou, Nikolas; Georgiou, Eleni...
What can respiratory viruses cause?
1,611
common colds, pharyngitis, croup, bronchiolitis, viral pneumonia and otitis media
2,207
1,566
Aetiology of Acute Respiratory Tract Infections in Hospitalised Children in Cyprus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720120/ SHA: efd27ff0ac04dd60838266386aaebb5df80f4fa9 Authors: Richter, Jan; Panayiotou, Christakis; Tryfonos, Christina; Koptides, Dana; Koliou, Maria; Kalogirou, Nikolas; Georgiou, Eleni...
When do respiratory infections usually happen?
1,613
during winter and early spring months
2,759
1,566
Aetiology of Acute Respiratory Tract Infections in Hospitalised Children in Cyprus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720120/ SHA: efd27ff0ac04dd60838266386aaebb5df80f4fa9 Authors: Richter, Jan; Panayiotou, Christakis; Tryfonos, Christina; Koptides, Dana; Koliou, Maria; Kalogirou, Nikolas; Georgiou, Eleni...
What are the most common viruses?
1,614
respiratory syncytial virus (RSV), influenza A and B (INF-A, INF-B) viruses, parainfluenza viruses (PIVs), and human adenoviruses (HAdVs)
2,831
1,566
Aetiology of Acute Respiratory Tract Infections in Hospitalised Children in Cyprus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720120/ SHA: efd27ff0ac04dd60838266386aaebb5df80f4fa9 Authors: Richter, Jan; Panayiotou, Christakis; Tryfonos, Christina; Koptides, Dana; Koliou, Maria; Kalogirou, Nikolas; Georgiou, Eleni...
What is the most common viral infection for infants up to 3 months old?
1,629
RSV
10,296
1,566
Aetiology of Acute Respiratory Tract Infections in Hospitalised Children in Cyprus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720120/ SHA: efd27ff0ac04dd60838266386aaebb5df80f4fa9 Authors: Richter, Jan; Panayiotou, Christakis; Tryfonos, Christina; Koptides, Dana; Koliou, Maria; Kalogirou, Nikolas; Georgiou, Eleni...
What is the incidence of RSV in children older than 3 years of age?
1,630
13%
10,507
1,548
The First Detection of Equine Coronavirus in Adult Horses and Foals in Ireland https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832964/ SHA: eee5a9068ade4c6776f189045115a90a5785e983 Authors: Nemoto, Manabu; Schofield, Warren; Cullinane, Ann Date: 2019-10-14 DOI: 10.3390/v11100946 License: cc-by Abstract: The objective...
What is the distance between the p4.7 and p12.7 genes in the Irish versus Japanese equine coronavirus variants?
2,125
544 base pairs
8,393
1,548
The First Detection of Equine Coronavirus in Adult Horses and Foals in Ireland https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832964/ SHA: eee5a9068ade4c6776f189045115a90a5785e983 Authors: Nemoto, Manabu; Schofield, Warren; Cullinane, Ann Date: 2019-10-14 DOI: 10.3390/v11100946 License: cc-by Abstract: The objective...
What is the difference between the Tokachi09 and Irish coronavirus genomic sequences?
2,126
148-nucleotide insertion
8,679
1,548
The First Detection of Equine Coronavirus in Adult Horses and Foals in Ireland https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832964/ SHA: eee5a9068ade4c6776f189045115a90a5785e983 Authors: Nemoto, Manabu; Schofield, Warren; Cullinane, Ann Date: 2019-10-14 DOI: 10.3390/v11100946 License: cc-by Abstract: The objective...
What suggests that Irish equine coronaviruses may have a low genetic diversity?
2,127
high level of homology between viruses
10,276
1,548
The First Detection of Equine Coronavirus in Adult Horses and Foals in Ireland https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832964/ SHA: eee5a9068ade4c6776f189045115a90a5785e983 Authors: Nemoto, Manabu; Schofield, Warren; Cullinane, Ann Date: 2019-10-14 DOI: 10.3390/v11100946 License: cc-by Abstract: The objective...
Where have most outbreaks of equine coronavirus occurred in the United States?
2,128
adult riding, racing and show horses
11,305
1,574
Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907881/ SHA: ef821e34873d4752ecae41cd9dfc08a5e6db45e2 Authors: Hughes, Michelle M; Englund, Janet A; Kuypers, Jane; Tielsch, James M; Khatry, Subarna K; Shrestha, Laxman; LeClerq...
What kind of pertussis vaccine is used in middle and high income countries?
2,167
acellular
2,107
1,574
Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907881/ SHA: ef821e34873d4752ecae41cd9dfc08a5e6db45e2 Authors: Hughes, Michelle M; Englund, Janet A; Kuypers, Jane; Tielsch, James M; Khatry, Subarna K; Shrestha, Laxman; LeClerq...
Where is the highest rate of childhood pertussis globally?
2,168
Southeast Asia
3,290
1,574
Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907881/ SHA: ef821e34873d4752ecae41cd9dfc08a5e6db45e2 Authors: Hughes, Michelle M; Englund, Janet A; Kuypers, Jane; Tielsch, James M; Khatry, Subarna K; Shrestha, Laxman; LeClerq...
What type of pertussis vaccine has been recently recommended by the WHO?
2,169
whole cell pertussis vaccines
3,739
1,574
Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907881/ SHA: ef821e34873d4752ecae41cd9dfc08a5e6db45e2 Authors: Hughes, Michelle M; Englund, Janet A; Kuypers, Jane; Tielsch, James M; Khatry, Subarna K; Shrestha, Laxman; LeClerq...
What are the clinical symptoms of pertussis?
2,170
apnea, cyanosis, cough with vomit, or whoop/whooping cough
6,426
1,574
Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907881/ SHA: ef821e34873d4752ecae41cd9dfc08a5e6db45e2 Authors: Hughes, Michelle M; Englund, Janet A; Kuypers, Jane; Tielsch, James M; Khatry, Subarna K; Shrestha, Laxman; LeClerq...
What type of swabs are used to sample patients with pertussis?
2,171
mid-nasal nylon flocked
6,206
1,574
Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907881/ SHA: ef821e34873d4752ecae41cd9dfc08a5e6db45e2 Authors: Hughes, Michelle M; Englund, Janet A; Kuypers, Jane; Tielsch, James M; Khatry, Subarna K; Shrestha, Laxman; LeClerq...
How frequently do pertussis outbreaks peak?
2,173
every 2 to 4 years
16,315
1,574
Population-Based Pertussis Incidence and Risk Factors in Infants Less Than 6 Months in Nepal https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907881/ SHA: ef821e34873d4752ecae41cd9dfc08a5e6db45e2 Authors: Hughes, Michelle M; Englund, Janet A; Kuypers, Jane; Tielsch, James M; Khatry, Subarna K; Shrestha, Laxman; LeClerq...
What is the WHO criteria for a pertussis infection?
2,174
a minimum of 2 weeks of cough, whoop, or posttussive vomiting
17,093
1,581
Estimating Sensitivity of Laboratory Testing for Influenza in Canada through Modelling https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722738/ SHA: f3a5b128f4800dbbb0f49ee409acb2c0216e24dc Authors: Schanzer, Dena L.; Garner, Michael J.; Hatchette, Todd F.; Langley, Joanne M.; Aziz, Samina; Tam, Theresa W. S. Date: 200...
What is used by the Canadian Public Health System to identify periods of influenza activity?
2,175
weekly proportion of laboratory tests that are positive for influenza
404
1,581
Estimating Sensitivity of Laboratory Testing for Influenza in Canada through Modelling https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722738/ SHA: f3a5b128f4800dbbb0f49ee409acb2c0216e24dc Authors: Schanzer, Dena L.; Garner, Michael J.; Hatchette, Todd F.; Langley, Joanne M.; Aziz, Samina; Tam, Theresa W. S. Date: 200...
Why is laboratory confirmation of influenza infection not commonly performed?
2,176
diagnosis will often not alter patient management, a paucity of real-time, accurate, inexpensive testing methods [4] and because influenza is not recognized as the etiology of the clinical presentation
1,987
1,581
Estimating Sensitivity of Laboratory Testing for Influenza in Canada through Modelling https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722738/ SHA: f3a5b128f4800dbbb0f49ee409acb2c0216e24dc Authors: Schanzer, Dena L.; Garner, Michael J.; Hatchette, Todd F.; Langley, Joanne M.; Aziz, Samina; Tam, Theresa W. S. Date: 200...
What types of viral infections are monitored through Canada's Respiratory Virus Detection Surveillance System (RVDSS)?
2,177
nfluenza, respiratory syncytial virus (RSV), para-influenza virus (PIV), and adenovirus
3,914
1,593
Can’t RIDD off viruses https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061530/ SHA: ef58c6e2790539f30df14acc260ae2af4b5f3d1f Authors: Bhattacharyya, Sankar Date: 2014-06-18 DOI: 10.3389/fmicb.2014.00292 License: cc-by Abstract: The mammalian genome has evolved to encode a battery of mechanisms, to mitigate a progress...
What is discussed in this publication?
2,466
the potential anti-virus activity of inositol-requiring enzyme 1 (IRE1), a well characterized effector of the cellular homeostatic response to an overloading of the endoplasmic reticulum (ER) protein-folding capacity. IRE1, an ER-membrane-resident ribonuclease (RNase), upon activation catalyses regulated cleavage of se...
582
1,593
Can’t RIDD off viruses https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061530/ SHA: ef58c6e2790539f30df14acc260ae2af4b5f3d1f Authors: Bhattacharyya, Sankar Date: 2014-06-18 DOI: 10.3389/fmicb.2014.00292 License: cc-by Abstract: The mammalian genome has evolved to encode a battery of mechanisms, to mitigate a progress...
What is discussed in this publication?
2,467
The review first discusses the anti-viral mechanism of the OAS/RNaseL system and evasion tactics employed by different viruses. This is followed by a review of the RIDD pathway and its potential effect on the stability of viral RNAs.
1,536
1,593
Can’t RIDD off viruses https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061530/ SHA: ef58c6e2790539f30df14acc260ae2af4b5f3d1f Authors: Bhattacharyya, Sankar Date: 2014-06-18 DOI: 10.3389/fmicb.2014.00292 License: cc-by Abstract: The mammalian genome has evolved to encode a battery of mechanisms, to mitigate a progress...
What is reported in this publication?
2,468
comparison of the enzymatic activity of the two RNases followed by deliberations on the physiological consequences of their activation.
1,788
1,593
Can’t RIDD off viruses https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061530/ SHA: ef58c6e2790539f30df14acc260ae2af4b5f3d1f Authors: Bhattacharyya, Sankar Date: 2014-06-18 DOI: 10.3389/fmicb.2014.00292 License: cc-by Abstract: The mammalian genome has evolved to encode a battery of mechanisms, to mitigate a progress...
What is the conclusion regarding IRE1 and RNaseL proteins?
2,469
In the context of a virus infection, the pathway leading from both these proteins have the potential to lead to cell death. Notwithstanding the fact that this might be an efficient way of virus clearance, it also portends pathological outcomes for the infected organism. Future research would probably lead to design of ...
28,670
1,550
Nearly Complete Genome Sequence of an Echovirus 30 Strain from a Cluster of Aseptic Meningitis Cases in California, September 2017 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953510/ SHA: f0c4d40e1879dd1a049298f151940ac168b5f5a7 Authors: Pan, Chao-Yang; Huynh, Thalia; Padilla, Tasha; Chen, Alice; Ng, Terry Fei Fan...
What is the structure of an Echovirus?
2,988
nonenveloped, single-stranded, positive-sense RNA
796
1,550
Nearly Complete Genome Sequence of an Echovirus 30 Strain from a Cluster of Aseptic Meningitis Cases in California, September 2017 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953510/ SHA: f0c4d40e1879dd1a049298f151940ac168b5f5a7 Authors: Pan, Chao-Yang; Huynh, Thalia; Padilla, Tasha; Chen, Alice; Ng, Terry Fei Fan...
What diseases are associated with echoviruses?
2,989
respiratory illness, hand-foot-and-mouth disease, and aseptic meningitis,
1,020
1,550
Nearly Complete Genome Sequence of an Echovirus 30 Strain from a Cluster of Aseptic Meningitis Cases in California, September 2017 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953510/ SHA: f0c4d40e1879dd1a049298f151940ac168b5f5a7 Authors: Pan, Chao-Yang; Huynh, Thalia; Padilla, Tasha; Chen, Alice; Ng, Terry Fei Fan...
In California, to where are meningitis cases reported according to the California Code of Regulations?
2,990
California Department of Public Health (CDPH)
1,220
1,550
Nearly Complete Genome Sequence of an Echovirus 30 Strain from a Cluster of Aseptic Meningitis Cases in California, September 2017 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953510/ SHA: f0c4d40e1879dd1a049298f151940ac168b5f5a7 Authors: Pan, Chao-Yang; Huynh, Thalia; Padilla, Tasha; Chen, Alice; Ng, Terry Fei Fan...
According to the California Code of Regulations, when should a meningitis case be reported?
2,991
within 1 day of identification
1,266
1,550
Nearly Complete Genome Sequence of an Echovirus 30 Strain from a Cluster of Aseptic Meningitis Cases in California, September 2017 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953510/ SHA: f0c4d40e1879dd1a049298f151940ac168b5f5a7 Authors: Pan, Chao-Yang; Huynh, Thalia; Padilla, Tasha; Chen, Alice; Ng, Terry Fei Fan...
Where is the Viral and Rickettsial Disease Laboratory located?
2,992
CDPH
1,499
1,550
Nearly Complete Genome Sequence of an Echovirus 30 Strain from a Cluster of Aseptic Meningitis Cases in California, September 2017 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953510/ SHA: f0c4d40e1879dd1a049298f151940ac168b5f5a7 Authors: Pan, Chao-Yang; Huynh, Thalia; Padilla, Tasha; Chen, Alice; Ng, Terry Fei Fan...
What type of reference genome was used in the study?
2,993
E-30
3,206
1,550
Nearly Complete Genome Sequence of an Echovirus 30 Strain from a Cluster of Aseptic Meningitis Cases in California, September 2017 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953510/ SHA: f0c4d40e1879dd1a049298f151940ac168b5f5a7 Authors: Pan, Chao-Yang; Huynh, Thalia; Padilla, Tasha; Chen, Alice; Ng, Terry Fei Fan...
What was the read coverage for the E-30 genome in this study?
2,994
260-fold
3,462
1,550
Nearly Complete Genome Sequence of an Echovirus 30 Strain from a Cluster of Aseptic Meningitis Cases in California, September 2017 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953510/ SHA: f0c4d40e1879dd1a049298f151940ac168b5f5a7 Authors: Pan, Chao-Yang; Huynh, Thalia; Padilla, Tasha; Chen, Alice; Ng, Terry Fei Fan...
What are the structural regions of the enterovirus polyprotein in this study?
2,995
one structural (P1-capsid) and two nonstructural (P2 and P3) regions
4,508
1,572
iNR-Drug: Predicting the Interaction of Drugs with Nuclear Receptors in Cellular Networking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975431/ SHA: ee55aea26f816403476a7cb71816b8ecb1110329 Authors: Fan, Yue-Nong; Xiao, Xuan; Min, Jian-Liang; Chou, Kuo-Chen Date: 2014-03-19 DOI: 10.3390/ijms15034915 License: cc-by...
What can nuclear receptors regulate?
1,635
homeostasis, differentiation, embryonic development, and organ physiology
2,040
1,572
iNR-Drug: Predicting the Interaction of Drugs with Nuclear Receptors in Cellular Networking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975431/ SHA: ee55aea26f816403476a7cb71816b8ecb1110329 Authors: Fan, Yue-Nong; Xiao, Xuan; Min, Jian-Liang; Chou, Kuo-Chen Date: 2014-03-19 DOI: 10.3390/ijms15034915 License: cc-by...
What are associated with cancer, diabetes, inflammatory disease, and osteoporosis?
3,258
Nuclear receptors (NRs)
332
1,572
iNR-Drug: Predicting the Interaction of Drugs with Nuclear Receptors in Cellular Networking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975431/ SHA: ee55aea26f816403476a7cb71816b8ecb1110329 Authors: Fan, Yue-Nong; Xiao, Xuan; Min, Jian-Liang; Chou, Kuo-Chen Date: 2014-03-19 DOI: 10.3390/ijms15034915 License: cc-by...
What are nuclear receptors (NRs)?
3,259
class of ligand-inducible transcription factors
1,939
1,572
iNR-Drug: Predicting the Interaction of Drugs with Nuclear Receptors in Cellular Networking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975431/ SHA: ee55aea26f816403476a7cb71816b8ecb1110329 Authors: Fan, Yue-Nong; Xiao, Xuan; Min, Jian-Liang; Chou, Kuo-Chen Date: 2014-03-19 DOI: 10.3390/ijms15034915 License: cc-by...
What biological factors for nuclear receptors regulate?
3,260
homeostasis, differentiation, embryonic development, and organ physiology
2,040
1,572
iNR-Drug: Predicting the Interaction of Drugs with Nuclear Receptors in Cellular Networking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975431/ SHA: ee55aea26f816403476a7cb71816b8ecb1110329 Authors: Fan, Yue-Nong; Xiao, Xuan; Min, Jian-Liang; Chou, Kuo-Chen Date: 2014-03-19 DOI: 10.3390/ijms15034915 License: cc-by...
How many families are in the NR superfamily?
3,261
seven
2,172
1,572
iNR-Drug: Predicting the Interaction of Drugs with Nuclear Receptors in Cellular Networking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975431/ SHA: ee55aea26f816403476a7cb71816b8ecb1110329 Authors: Fan, Yue-Nong; Xiao, Xuan; Min, Jian-Liang; Chou, Kuo-Chen Date: 2014-03-19 DOI: 10.3390/ijms15034915 License: cc-by...
What is a prerequisite to make a molecular docking study feasible?
3,262
a reliable 3D (three dimensional) structure of the target protein
3,102
1,572
iNR-Drug: Predicting the Interaction of Drugs with Nuclear Receptors in Cellular Networking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975431/ SHA: ee55aea26f816403476a7cb71816b8ecb1110329 Authors: Fan, Yue-Nong; Xiao, Xuan; Min, Jian-Liang; Chou, Kuo-Chen Date: 2014-03-19 DOI: 10.3390/ijms15034915 License: cc-by...
What tool can be used to determine the 3D structure of proteins?
3,263
X-ray crystallography
3,208
1,572
iNR-Drug: Predicting the Interaction of Drugs with Nuclear Receptors in Cellular Networking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975431/ SHA: ee55aea26f816403476a7cb71816b8ecb1110329 Authors: Fan, Yue-Nong; Xiao, Xuan; Min, Jian-Liang; Chou, Kuo-Chen Date: 2014-03-19 DOI: 10.3390/ijms15034915 License: cc-by...
What are the shortcomings of X-ray crystallography?
3,264
time-consuming and expensive
3,293
1,572
iNR-Drug: Predicting the Interaction of Drugs with Nuclear Receptors in Cellular Networking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975431/ SHA: ee55aea26f816403476a7cb71816b8ecb1110329 Authors: Fan, Yue-Nong; Xiao, Xuan; Min, Jian-Liang; Chou, Kuo-Chen Date: 2014-03-19 DOI: 10.3390/ijms15034915 License: cc-by...
What types of proteins are difficult to crystallize?
3,265
membrane proteins
3,401
1,572
iNR-Drug: Predicting the Interaction of Drugs with Nuclear Receptors in Cellular Networking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975431/ SHA: ee55aea26f816403476a7cb71816b8ecb1110329 Authors: Fan, Yue-Nong; Xiao, Xuan; Min, Jian-Liang; Chou, Kuo-Chen Date: 2014-03-19 DOI: 10.3390/ijms15034915 License: cc-by...
Where were the data collected for this study?
3,266
KEGG (Kyoto Encyclopedia of Genes and Genomes)
6,509
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
Who performed the sampling procedures?
3,680
veterinarians
2,560
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
When were the fecal samples collected?
3,681
from November 2004 to November 2014
2,855
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
What reference genome was used in the study?
3,682
BatCoV HKU10
4,900
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
What is the length of the replicase gene ORF1ab?
3,684
20.4 kb
12,855
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
What type of coronavirus was detected in R. affinis and R. sinicus species?
3,683
BtCoV/Rh/YN2012
11,997
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
What is a natural reservoir of coronavirus?
3,675
Bats
430
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
What is the genome size of the coronavirus?
3,676
26-32 kb
1,871
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
What is the structure of the coronavirus?
3,677
enveloped, non-segmented, positive-strand RNA viruses
1,786
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
What animals do gamma and delta coronavirus mainly infect?
3,678
birds
2,226
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
How many types of coronaviruses are known to cause human disease?
3,679
Six
2,275
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
What plays a role in regulating the immune response to a viral infection?
3,685
NF-κB
21,628
1,576
Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521148/ SHA: ee14de143337eec0e9708f8139bfac2b7b8fdd27 Authors: Wang, Ning; Luo, Chuming; Liu, Haizhou; Yang, Xinglou; Hu, Ben; Zhang, Wei; Li, Bei; Zhu, Yan; Zhu, Guangj...
What is the conclusion of the coronavirus long-term surveillance studies?
3,686
Rhinolophus bats seem to harbor a wide diversity of CoVs
28,444
1,590
In Vitro Antiviral Activity of Circular Triple Helix Forming Oligonucleotide RNA towards Feline Infectious Peritonitis Virus Replication https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950953/ SHA: f5ad2323eb387f6e271e2842bb2cc4a33504fde3 Authors: Choong, Oi Kuan; Mehrbod, Parvaneh; Tejo, Bimo Ario; Omar, Abdul Rahman...
What is the cause of Feline Infectious Peritonitis (FIP)?
4,051
FIP virus (FIPV)
503
1,590
In Vitro Antiviral Activity of Circular Triple Helix Forming Oligonucleotide RNA towards Feline Infectious Peritonitis Virus Replication https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950953/ SHA: f5ad2323eb387f6e271e2842bb2cc4a33504fde3 Authors: Choong, Oi Kuan; Mehrbod, Parvaneh; Tejo, Bimo Ario; Omar, Abdul Rahman...
What is the molecular structure of Feline Infectious Peritonitis Virus?
4,052
enveloped virus with a nonsegmented, positive sense, single-stranded RNA genome
1,635
1,590
In Vitro Antiviral Activity of Circular Triple Helix Forming Oligonucleotide RNA towards Feline Infectious Peritonitis Virus Replication https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950953/ SHA: f5ad2323eb387f6e271e2842bb2cc4a33504fde3 Authors: Choong, Oi Kuan; Mehrbod, Parvaneh; Tejo, Bimo Ario; Omar, Abdul Rahman...
How is FECV detected in cats?
4,053
shedding in their faeces
2,578
1,590
In Vitro Antiviral Activity of Circular Triple Helix Forming Oligonucleotide RNA towards Feline Infectious Peritonitis Virus Replication https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950953/ SHA: f5ad2323eb387f6e271e2842bb2cc4a33504fde3 Authors: Choong, Oi Kuan; Mehrbod, Parvaneh; Tejo, Bimo Ario; Omar, Abdul Rahman...
What type of vaccine is used to protect against FIPV infection?
4,055
an attenuated, temperature-sensitive strain of type II FIPV
2,958
1,590
In Vitro Antiviral Activity of Circular Triple Helix Forming Oligonucleotide RNA towards Feline Infectious Peritonitis Virus Replication https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950953/ SHA: f5ad2323eb387f6e271e2842bb2cc4a33504fde3 Authors: Choong, Oi Kuan; Mehrbod, Parvaneh; Tejo, Bimo Ario; Omar, Abdul Rahman...
Why is their controversy surrounding the FIPV vaccine?
4,056
the vaccine contains type 2 strain, whereas type 1 viruses are more prevalent in the field
3,185
1,590
In Vitro Antiviral Activity of Circular Triple Helix Forming Oligonucleotide RNA towards Feline Infectious Peritonitis Virus Replication https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950953/ SHA: f5ad2323eb387f6e271e2842bb2cc4a33504fde3 Authors: Choong, Oi Kuan; Mehrbod, Parvaneh; Tejo, Bimo Ario; Omar, Abdul Rahman...
For how long was the denatured polyacrylamide gel polymerized?
4,057
30 minutes
6,326
1,590
In Vitro Antiviral Activity of Circular Triple Helix Forming Oligonucleotide RNA towards Feline Infectious Peritonitis Virus Replication https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950953/ SHA: f5ad2323eb387f6e271e2842bb2cc4a33504fde3 Authors: Choong, Oi Kuan; Mehrbod, Parvaneh; Tejo, Bimo Ario; Omar, Abdul Rahman...
How was the binding strength measured?
4,058
nano Isothermal Titration Calorimeter (ITC)
7,176
1,578
Inhibitory Effect and Possible Mechanism of Action of Patchouli Alcohol against Influenza A (H2N2) Virus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264369/ SHA: f2d842780b9928cc70f38a4458553f2431877603 Authors: Wu, Huaxing; Li, Beili; Wang, Xue; Jin, Mingyuan; Wang, Guonian Date: 2011-08-03 DOI: 10.3390/molecules...
What was the focus of this study?
4,070
the anti-influenza A (H2N2) virus activity of patchouli alcohol
376
1,578
Inhibitory Effect and Possible Mechanism of Action of Patchouli Alcohol against Influenza A (H2N2) Virus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264369/ SHA: f2d842780b9928cc70f38a4458553f2431877603 Authors: Wu, Huaxing; Li, Beili; Wang, Xue; Jin, Mingyuan; Wang, Guonian Date: 2011-08-03 DOI: 10.3390/molecules...
What do neuroaminidase inhibitors target?
4,071
NA glycoproteins of influenza A and B virus
2,050
1,578
Inhibitory Effect and Possible Mechanism of Action of Patchouli Alcohol against Influenza A (H2N2) Virus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264369/ SHA: f2d842780b9928cc70f38a4458553f2431877603 Authors: Wu, Huaxing; Li, Beili; Wang, Xue; Jin, Mingyuan; Wang, Guonian Date: 2011-08-03 DOI: 10.3390/molecules...
What is the function of neuroaminidase in the influenza virus?
4,072
cleave the α-ketosidic linkage between terminal sialic acid and an adjacent sugar residue
2,227
1,578
Inhibitory Effect and Possible Mechanism of Action of Patchouli Alcohol against Influenza A (H2N2) Virus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264369/ SHA: f2d842780b9928cc70f38a4458553f2431877603 Authors: Wu, Huaxing; Li, Beili; Wang, Xue; Jin, Mingyuan; Wang, Guonian Date: 2011-08-03 DOI: 10.3390/molecules...
What is Tamiflu?
4,073
NA inhibitor
2,733
1,578
Inhibitory Effect and Possible Mechanism of Action of Patchouli Alcohol against Influenza A (H2N2) Virus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264369/ SHA: f2d842780b9928cc70f38a4458553f2431877603 Authors: Wu, Huaxing; Li, Beili; Wang, Xue; Jin, Mingyuan; Wang, Guonian Date: 2011-08-03 DOI: 10.3390/molecules...
What was the test for the level of cytotoxicity used in this study?
4,074
CC 50
4,844
1,578
Inhibitory Effect and Possible Mechanism of Action of Patchouli Alcohol against Influenza A (H2N2) Virus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264369/ SHA: f2d842780b9928cc70f38a4458553f2431877603 Authors: Wu, Huaxing; Li, Beili; Wang, Xue; Jin, Mingyuan; Wang, Guonian Date: 2011-08-03 DOI: 10.3390/molecules...
What method was used to measure the inhibition of viral replication?
4,075
MTT method
13,705
1,578
Inhibitory Effect and Possible Mechanism of Action of Patchouli Alcohol against Influenza A (H2N2) Virus https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264369/ SHA: f2d842780b9928cc70f38a4458553f2431877603 Authors: Wu, Huaxing; Li, Beili; Wang, Xue; Jin, Mingyuan; Wang, Guonian Date: 2011-08-03 DOI: 10.3390/molecules...
What was the conclusion of this study?
4,076
patchouli alcohol possesses anti-influenza A (H2N2) virus activity
18,530
1,584
Viral and bacterial co-infection in severe pneumonia triggers innate immune responses and specifically enhances IP-10: a translational study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138590/ SHA: ef3d6cabc804e5eb587b34249b539c1b5efa4cc4 Authors: Hoffmann, Jonathan; Machado, Daniela; Terrier, Olivier; Pouzol, Ste...
What statistical tests were used to compare categorical variables?
5,211
Chi-square test and Fisher's exact test
29,985
1,584
Viral and bacterial co-infection in severe pneumonia triggers innate immune responses and specifically enhances IP-10: a translational study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138590/ SHA: ef3d6cabc804e5eb587b34249b539c1b5efa4cc4 Authors: Hoffmann, Jonathan; Machado, Daniela; Terrier, Olivier; Pouzol, Ste...
What was a severe limitation of this study?
5,212
unable to evaluate the levels of immunomodulators in the serum samples of a control group
23,550