term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Endocytic vesicle membrane
10
43
3.136135
0.001712
P13473,Q14108,Q5KU26,Q8WTV0,Q93050,P11279,P02786,Q03518,Q15907,Q9Y487
Localization
GO Cellular component
msigdb_gocc
72,9,201,141,208,206,209,152,216,88
2301,2302,903,2702,749,1304,209,275,499,206,669,72,1679,1155,2185,1181,890,1085,1054,1979,430,1361,2407,2589,1391,152,1424,1425,2381,1807,9,771,2779,216,201,1987,1835,141,208,1511,1350,1850,88
-0.51428752530657,-0.51428752530657,0.34734463722339803,-0.8287583635800084,0.5142163574940924,0.07415070895816572,1.6979807301199143,1.4495286247621895,0.9094287765563077,1.7057429944746445,0.6194206088649225,2.291063262623579,-0.14270834812699967,0.1684982022009186,-0.43590826117893794,0.15301100508827867,0.361689967...
3,193
Lipid droplet
9
31
3.133926
0.001725
Q8NBQ5,Q07065,Q96RL7,O43760,Q99720,Q8NF37,Q01105,Q8NBX0,Q9H6V9
Localization
GO Cellular component
msigdb_gocc
324,73,178,78,50,181,278,154,62
2542,78,1555,1175,1048,888,2790,1522,959,655,1530,890,327,2584,278,73,752,788,1811,324,154,181,1480,560,178,50,803,62,860,2247,1439
-0.6777844648834328,2.2457277457630314,-0.07407874008591195,0.15301100508827867,0.22952714396117282,0.36168996784734275,-0.9414783391764264,-0.05719278632694883,0.30380731745916084,0.6322515068949177,-0.05719278632694883,0.36168996784734275,1.2650915011001496,-0.6988844633124501,1.4406894094750298,2.28546270022205,0.51...
3,193
Predicted secreted proteins
28
48
3.128854
0.001755
Q9H6E4,Q9BTY2,P80303,P78310,O00584,Q02818,Q07021,Q15165,P43490,Q9NZ08,O94813,P84157,Q9HB40,Q9Y4P3,P04083,Q9UMX5,O94919,Q99584,P02786,Q14667,Q9BUR5,O75718,Q9BRX8,P05067,Q8N128,P61916,Q08380,P26583
Functions
Protein Atlas Protein class
protein_atlas_protein_class
778,257,14,536,285,29,799,33,535,159,794,165,42,183,692,194,199,336,209,722,213,717,611,360,123,491,251,630
285,1785,1705,2397,717,794,199,209,692,360,2282,1522,1200,1651,2460,2008,2620,630,535,2658,2659,491,536,14,1626,165,29,799,251,2437,1058,722,33,809,123,3175,990,992,336,611,257,213,3019,778,42,159,194,183
1.413939040620315,-0.213128942203161,-0.16014273539632354,-0.5745186791895069,0.5542099181825546,0.45984406883424556,1.7364816398521126,1.6979807301199143,0.5805078633245453,1.1865067348823226,-0.494489054305589,-0.05719278632694883,0.1374300649717309,-0.12538587769838372,-0.6153848387722859,-0.32228307221127694,-0.741...
3,193
Establishment of protein localization to membrane
34
87
3.128412
0.001758
P43307,Q9P0J0,P40855,Q53H12,P98194,Q9NS69,Q9H4A6,Q9Y512,Q5J8M3,O14737,Q9GZY8,O43681,Q96A33,P61026,Q99442,Q9UGP8,P31751,Q15070,Q15904,Q8N2H4,Q9Y5L4,O60725,Q15907,Q9UHB9,P46379,Q9Y5J9,Q8WWC4,Q9UPN3,Q9NPA0,Q9HD20,Q15629,P27105,P49458,Q4J6C6
Processes and pathways
GO Biological process
msigdb_gobp
0,129,386,387,522,10,268,290,550,294,299,557,174,430,432,571,564,65,323,69,602,87,216,349,351,488,357,622,239,113,114,115,374,505
1729,1013,294,715,2033,557,919,87,2827,2576,1152,1048,1676,1413,2005,3064,115,2373,2908,564,2832,2550,386,2744,0,351,694,374,890,2468,2375,2899,1979,2434,430,941,3119,522,1605,1090,2499,2438,820,893,752,65,114,323,216,505,2226,387,550,2913,2798,761,69,909,647,357,174,949,432,299,930,268,932,1952,113,1147,239,1244,10,19...
-0.177690185818539,0.25950170179577764,1.38683389940539,0.5542099181825546,-0.3409024311136362,0.8048943132507087,0.3329162614491058,2.2284083926639537,-0.9877693062177954,-0.6988844633124501,0.1684982022009186,0.22952714396117282,-0.14270834812699967,0.009297339019232754,-0.32228307221127694,-1.492956015355766,2.13295...
3,193
Protein transmembrane transport
14
24
3.125901
0.001773
O60830,O95831,O75381,Q15388,Q9NS69,Q99442,Q15629,O96008,Q99595,P49755,Q9UGP8,P31751,O43615,O14925
Processes and pathways
GO Biological process
msigdb_gobp
5,389,263,232,10,432,114,525,19,304,571,564,376,92
92,376,5,263,1152,389,525,2458,1306,564,304,2899,2434,941,232,114,639,2798,928,432,19,1327,10,571
2.2109109040904884,1.1461017884280336,3.1165747016179965,1.4845046522176364,0.1684982022009186,1.1152930343193794,0.8751148153965543,-0.6153848387722859,0.07415070895816572,0.7929788244184839,1.3408498426869389,-1.082506135737104,-0.5948794930148794,0.3184040786732402,1.6023224295792171,2.1390803803002107,0.65770683599...
3,193
Organelle membrane contact site
10
16
3.122213
0.001795
Q96TC7,Q9NTJ5,Q5XKP0,Q9Y320,Q15388,P51572,Q8NHP6,Q96S66,P27824,Q14849
Localization
GO Cellular component
msigdb_gocc
384,486,260,423,232,327,340,403,311,58
666,1125,1555,525,311,327,1807,58,232,260,340,403,384,1350,486,423
0.6194206088649225,0.1838925440088085,-0.07407874008591195,0.8751148153965543,1.3221664240422288,1.2650915011001496,-0.213128942203161,2.394036011434074,1.6023224295792171,1.5017677751833673,1.2359622824697312,1.0735225288658525,1.1358809033740525,0.05808732403364699,0.9320183829658302,1.03093867386121
3,193
Pigment granule
25
59
3.120777
0.001804
Q15286,P61019,Q92820,O14773,P08195,P07237,P49755,P27824,Q15758,O43852,P21281,P35613,Q93050,P11279,P02786,Q92542,O75955,P11166,P04843,P05023,P27105,P62820,P62258,P55209,P57088
Localization
GO Cellular component
msigdb_gocc
771,520,529,150,417,684,304,311,565,315,693,192,208,206,209,211,338,612,490,363,115,758,633,502,255
150,315,903,338,209,490,363,1078,684,1522,1413,1387,417,1559,1622,2351,612,206,1597,1443,1679,693,2620,3129,115,311,1474,2037,1972,192,866,1084,304,2257,1528,1530,890,798,502,255,520,1130,633,758,1625,2041,2589,1807,944,1429,1937,771,565,2530,2055,211,529,208,2914
1.945483805688231,1.3033138565109923,0.34734463722339803,1.2359622824697312,1.6979807301199143,0.9207519138862322,1.176476578042439,0.21440615544338357,0.5935493889180543,-0.05719278632694883,0.009297339019232754,0.02566161901174243,1.0416622545332883,-0.07407874008591195,-0.1081741936250891,-0.5342242617338631,0.70780...
3,193
Snare complex
9
17
3.119137
0.001814
O60499,O95249,Q9P2W9,Q9UNK0,O14653,Q86Y82,O15400,Q13190,Q12981
Localization
GO Cellular component
msigdb_gocc
63,229,39,429,462,442,345,253,223
2301,462,345,782,63,903,229,472,1085,2080,1424,223,253,442,1487,39,429
-0.51428752530657,0.9543830980982788,1.216317751801572,0.4735513630461408,2.346058243177083,0.34734463722339803,1.6104756568747511,0.9432286304255554,0.21440615544338357,-0.3596472519831671,0.009297339019232754,1.6266810625618235,1.5188836640650665,0.9875161701203701,-0.023739075165896593,2.572831939044648,1.0201626829...
3,193
Coated vesicle
26
89
3.116959
0.001827
P24390,Q14108,P53634,P04439,O43731,Q9BVK6,Q8N511,Q9UBR2,O00165,P49755,Q15363,Q12907,P49257,P51572,P02786,Q9NR31,O15126,O14653,Q9Y3B3,Q5VW38,P42892,P05067,Q9Y3A6,Q9Y282,P10321,Q13190
Localization
GO Cellular component
msigdb_gocc
2,9,402,275,26,415,161,293,303,304,61,574,447,327,209,594,463,462,95,101,100,360,498,119,499,253
303,1013,1440,864,2486,462,715,463,26,2366,2104,1961,2424,903,2702,2651,2182,1521,749,1304,209,275,360,1677,499,2458,2351,669,1679,1155,2,1156,100,1053,447,304,1181,1203,327,1085,2962,2659,402,1054,2604,2315,1979,1055,1390,2407,2589,1391,574,253,2265,9,1752,771,61,2294,1632,2269,1987,101,599,161,1063,1511,415,1616,1881...
1.3408498426869389,0.25950170179577764,-0.007169221259632773,0.39013449402256833,-0.6360363435663436,0.9543830980982788,0.5542099181825546,0.9543830980982788,2.6816050945494077,-0.5543007948494578,-0.3785188752723304,-0.303787854117314,-0.5948794930148794,0.34734463722339803,-0.8287583635800084,-0.7848314137948916,-0.4...
3,193
primary active transporter
13
22
3.111501
0.001861
Q96NB2,P20020,P16615,Q6P4A7,O75381,Q15388,Q9NS69,P98194,Q8N4H5,P05023,O96008,Q9BUN8,Q15758
Functions
Panther Protein class
panther_protein_class
546,291,196,166,263,232,10,522,15,363,525,147,565
2397,263,1152,525,363,1676,3064,1016,196,291,798,522,232,565,166,15,546,147,705,601,1327,10
-0.5745186791895069,1.4845046522176364,0.1684982022009186,0.8751148153965543,1.176476578042439,-0.14270834812699967,-1.492956015355766,0.25950170179577764,1.751667447018552,1.3959088234962316,0.45984406883424556,0.8866106862369233,1.6023224295792171,0.7929788244184839,1.8760367688861144,2.9120109684113684,0.84027428658...
3,193
secondary carrier transporter
12
14
3.107222
0.001889
O75746,Q9BQT8,Q9UJS0,Q96ES6,P55011,Q9BXP2,Q9H936,Q15043,Q9UBX3,Q8TB61,Q9Y6M7,O95202
Functions
Panther Protein class
panther_protein_class
350,197,169,142,558,433,593,241,57,89,189,190
350,190,558,644,241,1209,89,142,197,433,593,57,169,189
1.2064269794639189,1.7667329517528663,0.8048943132507087,0.6450133877649504,1.5693674826960398,0.1374300649717309,2.2225958317358057,1.992569263975948,1.751667447018552,1.0093338760985888,0.7446925671515504,2.39928112695771,1.854681789652418,1.7742210599427393
3,193
Sphingolipid metabolism
7
10
3.104801
0.001904
O95470,Q16880,Q13510,Q06136,P17900,P07602,P04062
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
128,140,45,110,79,20,53
252,1198,128,53,20,79,110,45,140,556
1.5188836640650665,0.1374300649717309,2.0894866813375814,2.4355304023078563,2.762496989040066,2.2457277457630314,2.1512615372917634,2.5348046058833917,2.0123785518790727,0.8167483885125356
3,193
Amino acid transport
15
20
3.094681
0.00197
O75746,P08195,Q96NB2,Q6P4A7,Q8TDW0,Q9UJS0,Q9Y619,O75915,P55011,Q9H936,O60831,Q7L0J3,Q9H2J7,Q9H9B4,Q15758
Processes and pathways
GO Biological process
msigdb_gobp
350,417,546,166,484,169,267,551,558,593,489,149,705,601,565
2346,2031,489,350,551,1078,417,558,2555,752,565,166,149,484,546,705,593,601,169,267
-0.5342242617338631,-0.3409024311136362,0.9207519138862322,1.2064269794639189,0.8167483885125356,0.21440615544338357,1.0416622545332883,0.8048943132507087,-0.6777844648834328,0.5142163574940924,0.7929788244184839,1.8760367688861144,1.952285648216789,0.9320183829658302,0.8402742865808962,0.5805078633245453,0.74469256715...
3,193
Sensorimotor neuropathy
15
29
3.086336
0.002026
P00403,Q9Y2R0,Q13217,P40939,O95831,Q5KU26,P05023,Q9NR77,Q8N2K0,Q9NZJ7,P07602,Q15120,P07196,Q9Y4W6,O60313
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
195,4,549,631,389,201,363,49,371,148,20,476,438,677,221
1249,1198,221,389,195,363,438,20,1825,3129,2010,631,866,1388,850,686,2584,2218,1342,549,476,201,371,1839,49,1460,148,4,677
0.1059833465335269,0.1374300649717309,1.6266810625618235,1.1152930343193794,1.751667447018552,1.176476578042439,0.9875161701203701,2.762496989040066,-0.23102262249362931,-1.9000405921739463,-0.32228307221127694,0.6703324293561015,0.39013449402256833,0.02566161901174243,0.4042351666901161,0.5935493889180543,-0.698884463...
3,193
Transport vesicle membrane
17
45
3.085939
0.002029
O60499,P49257,P20020,O75592,O43760,O15126,P49755,P04439,Q7L0J3,O14653,Q86Y82,Q13190,Q15907,O76024,Q15363,Q9Y3B3,O95295
Localization
GO Cellular component
msigdb_gocc
63,447,291,445,78,463,304,275,149,462,442,253,216,247,61,95,409
1249,462,715,463,2366,78,63,1961,2424,903,445,247,2651,409,2182,1521,749,1304,275,1677,499,291,1679,447,304,890,1085,2604,2315,1130,758,2589,253,771,61,2294,1632,216,149,442,2095,594,2894,95,1854
0.1059833465335269,0.9543830980982788,0.5542099181825546,0.9543830980982788,-0.5543007948494578,2.2457277457630314,2.346058243177083,-0.303787854117314,-0.5948794930148794,0.34734463722339803,0.9765264378161742,1.5358542924197818,-0.7848314137948916,1.05233382643295,-0.43590826117893794,-0.05719278632694883,0.514216357...
3,193
Liposaccharide metabolic process
12
15
3.080837
0.002064
P06865,P07686,Q16880,Q9H490,P17900,P04066,Q92643,P16278,P06280,P04062,Q99805,Q8NBX0
Processes and pathways
GO Biological process
msigdb_gobp
224,584,140,366,79,591,468,82,244,53,343,154
756,53,591,244,224,584,82,79,140,154,468,1401,663,343,366
0.5007368375870117,2.4355304023078563,0.7446925671515504,1.5526815978228736,1.6185951277994044,0.7568588077238091,2.2399742438327923,2.2457277457630314,2.0123785518790727,1.9318034306318732,0.9543830980982788,0.02566161901174243,0.6322515068949177,1.2261627415331837,1.176476578042439
3,193
Primary active transmembrane transporter activity
23
48
3.079886
0.002071
Q9P0J0,Q9UDW1,P98194,O75027,O43676,P51970,O95168,Q03518,O75306,P08574,P20020,P47985,P06576,P08183,P00403,P16615,P28288,Q15388,P13073,P05023,Q7KZN9,Q9HD20,P51798
Functions
GO Molecular function
msigdb_gomf
129,6,522,397,16,656,404,152,543,668,291,679,552,176,195,196,473,232,109,363,112,113,383
2540,832,16,397,876,543,958,1557,404,1963,847,195,363,1676,552,176,668,1153,109,196,3040,291,981,693,2547,473,2959,1284,833,962,2998,679,3049,383,656,1361,522,152,232,1507,1002,112,113,2448,129,6,2151,935
-0.6777844648834328,0.4182557487269513,2.850934877568107,1.0945079100252835,0.3759530057373177,0.8402742865808962,0.30380731745916084,-0.07407874008591195,1.0629537868319574,-0.303787854117314,0.4042351666901161,1.751667447018552,1.176476578042439,-0.14270834812699967,0.8167483885125356,1.8112225085127378,0.61942060886...
3,193
Transport
193
483
3.072479
0.002123
Q9BQE5,P24390,O60830,Q9UDW1,Q9H2D1,P61019,Q9NS69,Q9C0H2,P98194,Q8TEX9,Q8N4H5,O43676,Q9NX14,Q99595,O96008,O43169,O43731,O95197,O75306,O00461,Q96NB2,Q13505,O14949,Q9P2W9,Q00325,P06576,P21912,O43681,P55011,O75964,P45880,Q99720,P21796,Q9UGP8,P31751,Q9UBX3,Q14849,Q15758,Q96CU9,Q15363,Q12907,O60499,Q8N2H4,Q9H1E5,Q70HW3,O7543...
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
1,2,5,6,7,520,10,11,522,528,15,16,530,19,525,25,26,27,543,34,546,36,37,39,554,552,553,557,558,47,48,50,51,571,564,57,58,565,60,61,574,63,69,75,77,583,582,593,594,83,602,86,601,88,89,92,95,97,616,613,612,106,618,627,113,114,623,119,120,636,639,129,134,135,642,644,138,664,142,143,661,660,147,148,149,656,152,155,669,162,6...
394,666,844,120,1729,2301,1383,1013,2540,3036,1103,2395,2541,34,1280,832,1196,1151,2486,916,462,470,92,37,767,2032,715,2033,463,106,453,782,642,25,1787,2542,1441,1921,2487,376,2250,16,557,1076,26,2366,191,444,1788,937,2104,63,1175,2543,957,1961,623,582,5,489,397,2398,2348,876,543,958,263,903,583,1412,1557,1047,1468,350...
1.1049253152266847,0.6194206088649225,0.4042351666901161,2.1206472108366774,-0.177690185818539,-0.51428752530657,0.02566161901174243,0.25950170179577764,-0.6777844648834328,-1.4118743308181245,0.19919490676105286,-0.5745186791895069,-0.6777844648834328,2.605360668935537,0.09011573382996567,0.4182557487269513,0.13743006...
3,193
Abnormal vertebral morphology
36
107
3.064528
0.00218
Q9UM00,Q15125,P51798,O95831,Q14108,Q13045,Q9Y619,Q9UHX1,Q9UBM7,Q96L58,P51812,Q8WVQ1,Q32P28,Q6NUK1,P04062,Q9Y4P3,O95202,Q8NCH0,Q96HY6,Q8N3U4,Q96AY3,O60826,P04066,P16278,Q14739,P10644,O15228,P10619,P15586,Q6NUQ1,Q10713,Q9BV10,O75845,P16435,O96028,P54802
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
385,131,383,389,9,391,267,12,400,272,527,283,545,419,53,183,190,70,326,588,328,582,591,82,210,604,471,98,225,483,236,111,238,248,382,126
1279,2134,765,2303,471,3099,1554,2000,1705,582,3029,717,238,2862,190,389,382,53,591,684,98,604,3164,225,82,248,1652,693,3065,2620,1415,2184,2603,2549,1079,2465,2466,1180,3056,1159,383,527,126,1308,2434,891,2934,2318,1421,2410,1391,1534,236,964,391,2606,9,1207,210,2047,1771,131,1289,2294,788,545,1657,613,2271,419,483,23...
0.09011573382996567,-0.39751866108604983,0.48718206135466036,-0.51428752530657,0.9432286304255554,-1.6613953871695926,-0.07407874008591195,-0.32228307221127694,-0.16014273539632354,0.7568588077238091,-1.3852918433246575,0.5542099181825546,1.5776579775269348,-1.0347727466327314,1.7667329517528663,1.1152930343193794,1.13...
3,193
Nervous system process
33
102
3.064268
0.002182
O00264,P53611,Q13432,P50897,Q14108,Q9UQB8,P10253,P53634,P49419,O14773,Q7L576,O75915,P04062,P07196,O75844,O75592,P07686,P17900,P04035,Q92542,O60313,O60443,O75746,Q9Y5J9,Q99797,P05067,Q13641,Q99538,Q99808,O76024,P42345,Q05086,Q6P4Q7
Processes and pathways
GO Biological process
msigdb_gobp
258,510,134,8,9,269,145,402,406,150,540,551,53,438,67,445,584,79,205,211,221,96,350,488,359,360,361,365,372,247,500,503,254
2985,258,2346,150,2905,221,96,2488,1706,2987,2489,445,1468,350,67,551,247,2307,205,53,2955,2654,360,1078,2282,438,584,145,1651,1306,79,2213,1825,2906,2138,1971,1525,1080,3023,500,2910,1081,1736,406,2523,2467,8,2217,510,402,2316,1744,2378,2409,2555,1605,503,1423,2836,2499,134,2265,361,9,1313,710,752,1288,2779,732,1774,2...
-1.2811099242588615,1.5017677751833673,-0.5342242617338631,1.945483805688231,-1.1066521830470757,1.6266810625618235,2.1932323689347277,-0.6360363435663436,-0.16014273539632354,-1.2811099242588615,-0.6360363435663436,0.9765264378161742,-0.023739075165896593,1.2064269794639189,2.329750012077,0.8167483885125356,1.53585429...
3,193
Glycosaminoglycan metabolism
8
12
3.064046
0.002184
P15586,Q7LGA3,P06865,Q8NCH0,O43505,P16278,Q8TB61,P54802
Processes and pathways
Reactome Pathways
msigdb_reactome
225,132,224,70,262,82,89,126
2396,262,224,584,225,82,126,132,70,89,272,2478
-0.5745186791895069,1.4845046522176364,1.6185951277994044,0.7568588077238091,1.6185951277994044,2.2399742438327923,2.095763221365341,2.070521741578072,2.302208489423922,2.2225958317358057,1.4583294958454196,-0.6153848387722859
3,193
Regulated exocytosis
12
40
3.063534
0.002187
P16615,P61026,Q99584,P09601,P11279,P49755,O43760,Q7L0J3,Q9BRK5,Q15907,O95721,O95295
Processes and pathways
GO Biological process
msigdb_gobp
196,430,336,17,206,304,78,149,151,216,472,409
2301,1383,2031,999,2905,2366,78,409,472,1730,1596,17,1306,206,196,1679,1598,2947,1018,304,1085,2080,2011,430,1605,1423,1424,2438,752,216,505,1234,1835,149,336,151,1148,1298,978,1277
-0.51428752530657,0.02566161901174243,-0.3409024311136362,0.27435692511880505,-1.1066521830470757,-0.5543007948494578,2.2457277457630314,1.05233382643295,0.9432286304255554,-0.177690185818539,-0.09107218097239303,2.850934877568107,0.07415070895816572,1.7057429944746445,1.751667447018552,-0.14270834812699967,-0.09107218...
3,193
Abnormal retinal artery morphology
8
18
3.058467
0.002225
P10619,P06865,Q13510,P17900,P16278,Q9NZJ7,P07602,Q9Y4P3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,224,45,79,82,148,20,183
1075,224,20,584,98,2676,82,79,288,2603,2604,2318,45,1771,2611,148,2067,183
0.21440615544338357,1.6185951277994044,2.762496989040066,0.7568588077238091,2.1872987787678158,-0.8067138905481915,2.2399742438327923,2.2457277457630314,1.4049437781239236,-0.7201373856155233,-0.7201373856155233,-0.51428752530657,2.5348046058833917,-0.1953518618147444,-0.7201373856155233,1.9590621281540601,-0.340902431...
3,193
Organophosphate ester transmembrane transporter activity
9
11
3.057122
0.002235
Q9BSK2,P12235,Q6NUK1,Q9H2D1,P12236,Q99808,Q8TB61,P05141,Q9HC21
Functions
GO Molecular function
msigdb_gomf
162,259,419,7,179,372,89,284,319
444,284,259,179,866,419,89,372,162,7,319
0.9765264378161742,1.4228948856937176,1.5017677751833673,1.803880161059405,0.39013449402256833,1.0416622545332883,2.2225958317358057,1.1663992693165688,1.8971479790749635,3.043830354362099,1.293823383957412
3,193
Nucleotide transmembrane transporter activity
9
11
3.057122
0.002235
Q9BSK2,P12235,Q6NUK1,Q9H2D1,P12236,Q99808,Q8TB61,P05141,Q9HC21
Functions
GO Molecular function
msigdb_gomf
162,259,419,7,179,372,89,284,319
444,284,259,179,866,419,89,372,162,7,319
0.9765264378161742,1.4228948856937176,1.5017677751833673,1.803880161059405,0.39013449402256833,1.0416622545332883,2.2225958317358057,1.1663992693165688,1.8971479790749635,3.043830354362099,1.293823383957412
3,193
Cellular homeostasis
56
141
3.05625
0.002241
Q96TC7,Q8N183,Q9UM00,P50897,P98194,O75880,O75503,O75027,P09601,P10253,P62942,Q7L0J3,Q8N5M9,O95295,Q16611,Q8N511,P20020,P06576,Q8IYU8,P55011,Q96A33,O43819,Q9BPX6,Q9BXP2,P52789,Q9NQC3,Q9Y6M7,Q9UJZ1,O95202,Q16891,Q15904,P16615,P13473,P51572,P07686,O60826,Q93050,P02786,Q8TAD4,Q9Y487,Q15907,Q9BWH2,O00330,Q15120,Q92544,Q8WWC...
Processes and pathways
GO Biological process
msigdb_gobp
384,641,385,8,522,395,139,397,17,145,276,149,279,409,544,161,291,552,425,558,174,175,301,433,435,59,189,577,190,318,323,196,72,327,584,582,208,209,86,88,216,479,603,476,353,357,360,363,113,241,116,372,508,247,503,633
1383,1013,603,2541,916,2346,175,2488,582,397,139,395,3160,247,190,1647,409,2829,2637,209,3150,363,1676,360,1596,552,584,1387,2369,1200,17,796,2722,145,2917,72,2352,1443,2008,196,1623,2989,1501,2252,291,2288,2309,2906,3117,2185,2138,3030,3074,2930,3091,3055,2998,1081,2187,2039,8,890,924,327,3161,1799,435,1898,798,558,25...
0.02566161901174243,0.25950170179577764,0.7201675789757652,-0.6777844648834328,0.3329162614491058,-0.5342242617338631,1.8185362415383943,-0.6360363435663436,0.7568588077238091,1.0945079100252835,2.0123785518790727,1.1049253152266847,-2.361815391886055,1.5358542924197818,1.7667329517528663,-0.12538587769838372,1.0523338...
3,193
Abnormal form of the vertebral bodies
32
84
3.044911
0.002327
Q9UM00,Q15125,P51798,O95831,Q13045,Q9Y619,Q9UHX1,Q9UBM7,Q96L58,P51812,Q8WVQ1,Q32P28,Q6NUK1,Q9Y4P3,O95202,Q96HY6,Q8N3U4,Q96AY3,O60826,P04066,P16278,Q14739,P10644,O15228,P15586,Q6NUQ1,Q10713,Q9BV10,O75845,P16435,O96028,P54802
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
385,131,383,389,391,267,12,400,272,527,283,545,419,183,190,326,588,328,582,591,82,210,604,471,225,483,236,111,238,248,382,126
1279,2134,765,2303,471,3099,1554,1705,582,3029,238,2862,190,389,382,591,684,604,225,82,248,1652,693,3065,2620,1415,2184,2603,2549,1079,2465,2466,1180,3056,1159,383,527,126,2434,2934,2318,2410,1391,1534,236,964,391,2606,210,2047,1771,131,1289,2294,545,1657,613,419,483,2506,588,947,283,328,1041,326,1458,272,1486,111,3027...
0.09011573382996567,-0.39751866108604983,0.48718206135466036,-0.51428752530657,0.9432286304255554,-1.6613953871695926,-0.07407874008591195,-0.16014273539632354,0.7568588077238091,-1.3852918433246575,1.5776579775269348,-1.0347727466327314,1.7667329517528663,1.1152930343193794,1.1358809033740525,0.7446925671515504,0.5935...
3,193
Lipid biosynthetic process
55
137
3.043547
0.002338
O95470,Q15125,Q53H12,Q9H7Z7,Q9UKR5,Q16880,Q8WTV0,Q9UBM7,Q9HCL2,Q8NBX0,Q53GQ0,P35610,O00767,Q92604,Q9NPH0,Q14534,Q16850,Q86YN1,Q13510,P04062,Q8NF37,Q6UWP7,Q14849,Q8NCC3,Q8NBQ5,O75592,P49748,P30536,Q9P035,Q86UL3,P04035,Q92643,Q14739,Q15392,Q99805,O95674,O15228,P28288,Q9NTJ5,P37268,Q9BY49,O95864,Q15800,Q10713,Q9H490,Q0613...
Processes and pathways
GO Biological process
msigdb_gobp
128,131,387,393,266,140,141,400,281,154,286,410,416,289,168,297,170,171,45,53,181,441,58,193,324,445,455,200,203,334,205,468,210,84,343,377,471,473,486,99,231,482,107,236,366,110,238,363,496,242,493,507,118,248,252
884,1278,864,2541,3169,416,766,471,252,1198,2905,1823,756,445,238,2862,1962,1015,128,1048,377,3139,482,2878,888,205,53,692,363,584,959,2403,2106,2460,2077,2957,3162,248,1623,3073,2309,1931,2704,2883,473,2521,200,1202,410,242,99,2793,500,2706,655,685,1084,455,2684,2948,750,3097,2981,1391,110,1092,236,3192,45,3120,868,29...
0.36168996784734275,0.09011573382996567,0.39013449402256833,-0.6777844648834328,-2.6169954275388214,1.0416622545332883,0.48718206135466036,0.9432286304255554,1.5188836640650665,0.1374300649717309,-1.1066521830470757,-0.23102262249362931,0.5007368375870117,0.9765264378161742,1.5776579775269348,-1.0347727466327314,-0.303...
3,193
Metabolism of lipids
72
180
3.030977
0.002438
O95470,Q15125,Q53H12,P09960,Q9H7Z7,P50897,Q16880,Q8WVX9,Q9UBM7,P07602,Q9NZJ7,Q9HCL2,P38435,Q53GQ0,P35610,O00767,Q15165,Q92604,Q9NPJ6,Q9NQZ5,Q15067,P23786,Q9NZ01,P48163,Q9NPH0,Q16850,Q14534,O43681,Q13510,P04062,Q8NF37,Q6UWP7,Q8IV08,P53007,Q14849,Q9UMR5,O43772,Q8NCC3,O43808,Q8NBQ5,O75448,P49748,P51648,Q8NAN2,P30536,Q9P03...
Processes and pathways
Reactome Pathways
msigdb_reactome
128,131,387,264,393,8,140,524,400,20,148,281,157,286,410,416,33,289,547,163,420,167,556,41,168,170,297,557,45,53,181,441,184,440,58,188,191,193,444,324,454,455,71,457,200,203,79,205,334,469,82,210,84,471,486,98,99,224,231,482,107,236,365,110,238,496,242,244,507,118,377,252
666,667,884,1278,864,2541,3169,416,766,471,252,1198,2905,557,191,444,1555,1175,2002,454,2739,238,1647,128,2182,1521,1048,377,482,2878,205,53,3187,848,244,224,20,584,3146,264,98,3138,2077,2957,1258,3162,82,79,2287,1154,1679,1127,2309,1931,2704,167,2883,1601,200,1202,833,2705,410,242,3031,99,157,631,1226,2706,1052,41,655...
0.6194206088649225,0.6194206088649225,0.36168996784734275,0.09011573382996567,0.39013449402256833,-0.6777844648834328,-2.6169954275388214,1.0416622545332883,0.48718206135466036,0.9432286304255554,1.5188836640650665,0.1374300649717309,-1.1066521830470757,0.8048943132507087,1.7592151429408447,0.9765264378161742,-0.074078...
3,193
Copii coated er to golgi transport vesicle
16
31
3.028185
0.00246
P49257,Q9UBR2,P05067,Q9Y3A6,P53634,P49755,P04439,Q9NR31,O14653,Q9Y282,Q13190,Q9BVK6,P10321,Q15363,Q9Y3B3,Q12907
Localization
GO Cellular component
msigdb_gocc
447,293,360,498,402,304,275,594,462,119,253,415,499,61,95,574
462,715,1961,2424,903,2651,2182,1521,1304,275,360,499,447,304,402,2604,2315,574,253,61,2294,1632,599,415,594,293,2894,119,498,95,1854
0.9543830980982788,0.5542099181825546,-0.303787854117314,-0.5948794930148794,0.34734463722339803,-0.7848314137948916,-0.43590826117893794,-0.05719278632694883,0.07415070895816572,1.4495286247621895,1.1865067348823226,0.9094287765563077,0.9765264378161742,1.3408498426869389,1.0735225288658525,-0.7201373856155233,-0.5142...
3,193
Calcium ion binding
23
80
3.017183
0.002551
P80303,O43149,Q9BRK5,Q8WVQ1,Q02818,Q6NUK1,Q9Y680,Q9UJS0,Q8IYU8,Q96A33,Q9BPX6,Q8NF37,Q9NWM8,P27824,Q14257,O43852,O95202,P16615,Q96AY3,P55327,Q99584,O60476,O75746
Functions
GO Molecular function
msigdb_gomf
14,401,151,283,29,419,40,169,425,174,301,181,182,311,186,315,190,196,328,333,336,346,350
666,1104,401,557,1076,315,346,2424,445,350,794,190,692,1791,1522,2137,1387,1860,1764,2352,3164,1256,1443,1258,196,3073,1177,1501,1445,1598,2185,311,2907,3091,2898,1654,1052,1566,1528,333,2469,963,1089,14,1805,29,2836,1452,836,1428,186,681,2871,759,2169,419,2798,969,1137,425,181,283,174,328,993,336,883,301,151,1026,764,...
0.6194206088649225,0.19919490676105286,1.0735225288658525,0.8048943132507087,0.21440615544338357,1.3033138565109923,1.216317751801572,-0.5948794930148794,0.9765264378161742,1.2064269794639189,0.45984406883424556,1.7667329517528663,0.5805078633245453,-0.213128942203161,-0.05719278632694883,-0.39751866108604983,0.0256616...
3,193
Synaptic vesicle membrane
8
16
3.015828
0.002563
O60499,P20020,O43760,Q7L0J3,Q86Y82,Q15907,O76024,O95295
Localization
GO Cellular component
msigdb_gocc
63,291,78,149,442,216,247,409
1249,463,78,63,247,409,1677,291,1679,890,1130,771,216,149,442,2095
0.1059833465335269,0.9543830980982788,2.2457277457630314,2.346058243177083,1.5358542924197818,1.05233382643295,-0.14270834812699967,1.3959088234962316,-0.14270834812699967,0.36168996784734275,0.1838925440088085,0.48718206135466036,1.6586937760640963,1.952285648216789,0.9875161701203701,-0.3596472519831671
3,193
Abnormality of head blood vessel
8
21
3.009164
0.00262
P10619,P06865,Q13510,P17900,P16278,Q9NZJ7,P07602,Q9Y4P3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
98,224,45,79,82,148,20,183
2303,1075,224,20,584,98,2676,82,79,288,2603,685,2604,2318,45,1771,1987,2611,148,2067,183
-0.51428752530657,0.21440615544338357,1.6185951277994044,2.762496989040066,0.7568588077238091,2.1872987787678158,-0.8067138905481915,2.2399742438327923,2.2457277457630314,1.4049437781239236,-0.7201373856155233,0.5935493889180543,-0.7201373856155233,-0.51428752530657,2.5348046058833917,-0.1953518618147444,-0.30378785411...
3,193
Delusions
6
21
3.007606
0.002633
Q9BQE5,Q9UJS0,Q96RL7,P07602,Q9NZJ7,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,169,178,20,148,53
765,557,53,20,1708,1258,288,2521,1032,1081,1711,2374,2015,2607,1142,178,1,1459,148,2537,169
0.48718206135466036,0.8048943132507087,2.4355304023078563,2.762496989040066,-0.16014273539632354,0.1059833465335269,1.4049437781239236,-0.656835659642823,0.2445587153188426,0.21440615544338357,-0.16014273539632354,-0.5543007948494578,-0.32228307221127694,-0.7201373856155233,0.1838925440088085,1.8112225085127378,3.26832...
3,193
Chemical homeostasis
70
182
3.001434
0.002687
Q96TC7,Q9UM00,P50897,P42785,P98194,Q6IAA8,O75503,Q8WTV0,O75880,Q9Y6C9,Q5BJF2,P09601,O75027,P62942,Q7L0J3,Q8N5M9,Q8NE01,Q9HCL2,P53985,Q86YV9,P35610,O95295,P30519,Q16611,Q8N511,P20020,Q15067,P06576,Q8IYU8,P55011,Q96A33,O43819,Q9BPX6,Q9BXP2,P52789,P04062,Q8NF37,Q9NQC3,Q9Y6M7,Q9UJZ1,O95202,Q16891,Q15904,P16615,P51572,P3053...
Processes and pathways
GO Biological process
msigdb_gobp
384,385,8,136,522,523,139,141,395,143,144,17,397,276,149,279,280,281,407,412,410,409,32,544,161,291,420,552,425,558,174,175,301,433,435,53,181,59,189,577,190,318,323,196,327,200,584,203,208,209,86,88,216,479,476,353,357,360,363,113,241,116,372,245,373,247,491,503,501,254
1383,1013,603,2541,1822,916,2346,2033,1621,245,175,2488,582,397,139,395,3160,247,2307,190,1647,409,2182,1763,209,53,2955,1730,363,1676,360,1596,552,1649,2282,584,1387,2369,1200,959,17,2428,2722,2917,2352,1443,2957,196,1623,1259,2491,2989,1966,1501,2252,291,2288,2309,2906,3117,2185,1600,2138,2831,32,200,3091,2705,410,29...
0.02566161901174243,0.25950170179577764,0.7201675789757652,-0.6777844648834328,-0.23102262249362931,0.3329162614491058,-0.5342242617338631,-0.3409024311136362,-0.1081741936250891,1.5442857407745552,1.8185362415383943,-0.6360363435663436,0.7568588077238091,1.0945079100252835,2.0123785518790727,1.1049253152266847,-2.3618...
3,193
Snap receptor activity
9
15
2.999562
0.002704
O60499,O95249,Q9P2W9,Q9UNK0,O14653,Q86Y82,O15400,Q13190,Q12981
Functions
GO Molecular function
msigdb_gomf
63,229,39,429,462,442,345,253,223
2301,462,345,782,63,903,229,472,1085,1424,223,253,442,39,429
-0.51428752530657,0.9543830980982788,1.216317751801572,0.4735513630461408,2.346058243177083,0.34734463722339803,1.6104756568747511,0.9432286304255554,0.21440615544338357,0.009297339019232754,1.6266810625618235,1.5188836640650665,0.9875161701203701,2.572831939044648,1.0201626829533696
3,193
Snare interactions in vesicular transport
9
15
2.999562
0.002704
O60499,O95249,Q9P2W9,Q9UNK0,O14653,Q86Y82,O15400,Q13190,Q12981
Processes and pathways
KEGG Pathways
msigdb_kegg
63,229,39,429,462,442,345,253,223
2301,462,345,782,63,903,229,472,1085,1424,223,253,442,39,429
-0.51428752530657,0.9543830980982788,1.216317751801572,0.4735513630461408,2.346058243177083,0.34734463722339803,1.6104756568747511,0.9432286304255554,0.21440615544338357,0.009297339019232754,1.6266810625618235,1.5188836640650665,0.9875161701203701,2.572831939044648,1.0201626829533696
3,193
Hexosyltransferase activity
14
32
2.988293
0.002805
Q6ZXV5,P06865,O43505,Q16880,P07686,P46977,P04843,Q9BV10,Q96L58,Q9BT22,Q8TCJ2,P04062,Q13126,Q2TAA5
Functions
GO Molecular function
msigdb_gomf
160,224,262,140,584,204,490,111,272,342,467,53,55,312
2134,2650,262,1705,756,2424,53,490,815,1649,224,584,1895,1861,1260,1035,204,1534,605,55,140,312,160,1136,1270,467,272,342,111,1045,997,3159
-0.39751866108604983,-0.7848314137948916,1.4845046522176364,-0.16014273539632354,0.5007368375870117,-0.5948794930148794,2.4355304023078563,0.9207519138862322,0.4321969562595515,-0.12538587769838372,1.6185951277994044,0.7568588077238091,-0.2671646500903092,-0.24903411518852805,0.1059833465335269,0.2445587153188426,1.721...
3,193
Inorganic anion transport
19
27
2.984338
0.002842
Q9Y277,Q9C0H2,Q96S66,Q00325,O43681,P55011,P45880,P08183,Q9BXP2,P21796,Q9UBX3,Q9Y6M7,P30536,Q9NW15,Q8TDW0,Q9UHG3,Q9H0H5,Q15043,P51798
Processes and pathways
GO Biological process
msigdb_gobp
135,11,403,554,557,558,48,176,433,51,57,189,200,220,484,105,627,241,383
3036,557,176,2722,51,200,833,48,3161,383,1898,558,554,644,241,3026,484,403,433,11,627,220,57,105,135,2211,189
-1.4118743308181245,0.8048943132507087,1.8112225085127378,-0.8509667351664257,2.5007588066882245,1.7364816398521126,0.4182557487269513,2.515439795372476,-2.3972018839891502,1.1358809033740525,-0.2671646500903092,0.8048943132507087,0.8167483885125356,0.6450133877649504,1.5693674826960398,-1.3589269339837995,0.9320183829...
3,193
SNARE protein
8
12
2.983486
0.00285
O60499,O95249,Q9P2W9,Q9UNK0,O14653,Q86Y82,O15400,Q13190
Functions
Panther Protein class
panther_protein_class
63,229,39,429,462,442,345,253
2301,462,345,63,229,472,1085,1424,253,442,39,429
-0.51428752530657,0.9543830980982788,1.216317751801572,2.346058243177083,1.6104756568747511,0.9432286304255554,0.21440615544338357,0.009297339019232754,1.5188836640650665,0.9875161701203701,2.572831939044648,1.0201626829533696
3,193
SNARE protein
8
12
2.983486
0.00285
O60499,O95249,Q9P2W9,Q9UNK0,O14653,Q86Y82,O15400,Q13190
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
63,229,39,429,462,442,345,253
2301,462,345,63,229,472,1085,1424,253,442,39,429
-0.51428752530657,0.9543830980982788,1.216317751801572,2.346058243177083,1.6104756568747511,0.9432286304255554,0.21440615544338357,0.009297339019232754,1.5188836640650665,0.9875161701203701,2.572831939044648,1.0201626829533696
3,193
Ventricular hypertrophy
18
36
2.976693
0.002914
O43772,Q13724,P12235,Q6NUK1,P00403,O75844,P23786,P02545,O75880,P21912,O75431,P54098,Q9BV10,P10253,P06280,O75208,P40939,Q15233
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
191,511,259,419,195,67,167,643,395,553,583,686,111,145,244,563,631,673
1279,191,563,583,67,395,691,195,643,244,145,1651,259,1861,553,167,1795,1260,962,2657,631,2745,1035,686,2218,799,2412,511,673,419,1477,2767,947,841,111,1881
0.09011573382996567,1.7592151429408447,0.7929788244184839,0.7568588077238091,2.329750012077,1.1049253152266847,0.5805078633245453,1.751667447018552,0.6450133877649504,1.5526815978228736,1.9658133945446885,-0.12538587769838372,1.5017677751833673,-0.24903411518852805,0.8167483885125356,1.8618274754931423,-0.2131289422031...
3,193
Mitochondrial nucleotide transporter subfamily
8
9
2.974291
0.002937
Q9BSK2,P12235,Q6NUK1,Q9H2D1,Q70HW3,P12236,P05141,Q9HC21
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
162,259,419,7,77,179,284,319
444,284,259,179,419,77,162,7,319
0.9765264378161742,1.4228948856937176,1.5017677751833673,1.803880161059405,1.0416622545332883,2.2514617717609795,1.8971479790749635,3.043830354362099,1.293823383957412
3,193
Rhog gtpase cycle
10
34
2.973844
0.002941
P49257,P50402,Q6IAA8,Q86XL3,P02786,Q14739,O15173,P42167,Q13190,O95202
Processes and pathways
Reactome Pathways
msigdb_reactome
447,261,523,335,209,210,56,249,253,190
56,782,1557,190,1647,209,1078,2355,1417,249,447,261,890,1604,2163,1205,2358,2293,1231,253,1749,1428,210,1507,1317,523,540,733,335,1777,2534,1026,1587,1375
2.39928112695771,0.4735513630461408,-0.07407874008591195,1.7667329517528663,-0.12538587769838372,1.6979807301199143,0.21440615544338357,-0.5342242617338631,0.009297339019232754,1.5358542924197818,0.9765264378161742,1.4931547427369818,0.36168996784734275,-0.09107218097239303,-0.41664798954862137,0.1374300649717309,-0.53...
3,193
Cytochrome complex assembly
8
13
2.967446
0.003003
Q15070,Q9BSK2,Q9Y2R0,O43819,Q7KZN9,Q69YU5,Q6DKK2,P53701
Processes and pathways
GO Biological process
msigdb_gobp
65,162,4,175,112,22,219,317
175,395,679,317,65,22,219,112,712,910,162,862,4
1.8185362415383943,1.1049253152266847,0.6065201023101452,1.3033138565109923,2.3406400045953175,2.745828206525584,1.6427531946624607,2.1451816415421097,0.5673949130081869,0.34734463722339803,1.8971479790749635,0.4042351666901161,3.129385678191442
3,193
Mitochondrial carrier protein [IPR002067]
10
11
2.94862
0.003192
O75746,O43808,P12235,Q6NUK1,Q9BQT8,Q9UJS0,P12236,P53007,P05141,Q9HC21
Sequence
InterPro Family
interpro_family
350,444,259,419,197,169,179,440,284,319
444,350,284,259,179,440,419,197,593,319,169
0.9765264378161742,1.2064269794639189,1.4228948856937176,1.5017677751833673,1.803880161059405,0.9875161701203701,1.0416622545332883,1.751667447018552,0.7446925671515504,1.293823383957412,1.854681789652418
3,193
Mitochondrial calcium ion transport
13
16
2.941004
0.003272
Q99623,Q8WWC4,Q9Y277,Q10713,Q8IYU8,Q9BPX6,O95202,P45880,Q8NE86,P21796,Q9Y4W6,Q96TA2,Q9UJZ1
Processes and pathways
Reactome Pathways
msigdb_reactome
388,357,135,236,425,301,190,48,724,51,677,348,577
2072,190,51,786,48,236,425,724,357,1239,348,388,301,577,135,677
-0.3596472519831671,1.7667329517528663,2.5007588066882245,0.4735513630461408,2.515439795372476,1.5859138151123813,1.0201626829533696,0.5542099181825546,1.1964900873490003,0.12175448251162654,1.216317751801572,1.125611440557737,1.350128868152097,0.7810014179820873,2.051351117777622,0.6194206088649225
3,193
Protein transporter activity
10
13
2.932908
0.003358
Q9Y5J9,O60830,Q15388,Q9NS69,Q9HD20,O96008,P49755,Q99595,Q9UGP8,O14925
Functions
GO Molecular function
msigdb_gomf
488,5,232,10,113,525,304,19,571,92
92,5,1152,525,304,941,232,647,19,113,10,571,488
2.2109109040904884,3.1165747016179965,0.1684982022009186,0.8751148153965543,1.3408498426869389,0.3184040786732402,1.6023224295792171,0.6450133877649504,2.8113998714497686,2.1451816415421097,3.0024397548003465,0.7929788244184839,0.9320183829658302
3,193
Abnormality of the cerebrospinal fluid
52
137
2.928488
0.003406
Q9P0J0,Q8N183,Q15125,P40855,O95831,O43505,Q9UBM7,Q9NX14,O43676,Q96L58,Q16625,P07602,Q6PI48,P51970,Q9NZJ7,P18074,O75306,P21964,Q6NUK1,P23786,Q03252,O43681,P55011,O43819,P07237,Q9NR77,P48651,P54098,P04062,Q96CU9,P53701,O95202,Q9HC21,P00403,Q8N3U4,O60826,Q9NPL8,Q15392,O43464,P20700,O00330,P10644,Q9Y5P6,O15360,P11166,Q9H49...
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
129,641,131,386,389,262,400,530,16,272,532,20,533,656,148,653,543,288,419,167,680,557,558,175,684,49,685,686,53,60,317,190,319,195,588,582,727,84,716,719,603,604,747,481,612,366,236,109,112,248,382,383
2540,603,2541,832,765,2303,481,885,716,262,16,557,175,1499,2001,582,876,543,1442,958,1557,2035,769,190,847,389,382,195,53,1356,684,20,2076,604,612,109,1258,248,653,3040,1224,719,3065,288,167,2372,2959,2493,1601,938,1795,1128,2549,2356,1079,2793,386,3012,1034,685,2582,1037,3049,2217,383,656,2112,317,2604,686,558,2113,10...
-0.6777844648834328,0.7201675789757652,-0.6777844648834328,0.4182557487269513,0.48718206135466036,-0.51428752530657,0.9320183829658302,0.36168996784734275,0.5542099181825546,1.4845046522176364,2.850934877568107,0.8048943132507087,1.8185362415383943,-0.04041324981336907,-0.32228307221127694,0.7568588077238091,0.37595300...
3,193
Hormone metabolic process
14
32
2.92687
0.003424
O95470,O75844,Q8NBQ5,Q9UBR2,P42892,P30536,Q9HB40,Q6NUM9,P05023,Q8TAD4,P16435,Q14849,Q53GQ0,Q8NBN7
Processes and pathways
GO Biological process
msigdb_gobp
128,67,324,293,100,200,42,207,363,86,248,58,286,287
1823,67,1962,128,363,959,2008,2957,248,200,100,3149,850,2887,58,1939,286,207,809,287,324,86,896,2818,898,2839,42,827,400,293,2877,531
-0.23102262249362931,2.329750012077,-0.303787854117314,2.0894866813375814,1.176476578042439,0.30380731745916084,-0.32228307221127694,-1.2051532199617174,1.5358542924197818,1.7364816398521126,2.181344630255124,-2.189902884432974,0.4042351666901161,-1.0585470825916556,2.394036011434074,-0.28541547461577405,1.413939040620...
3,193
Golgi apparatus subcompartment
39
92
2.91718
0.003532
P98194,Q9H4A6,Q96L58,Q7Z3C6,P04439,Q8WVQ1,P11717,O00461,Q9UNK0,Q8TBA6,P61026,P04062,Q9Y3A3,Q15363,P46459,O60499,O14578,O75592,Q8N2H4,Q12893,P51572,O15126,Q16706,Q5VYK3,Q10471,Q8WVM8,O14828,Q4J6C6,O95249,Q969E2,P05067,O15127,Q10713,Q9NXE4,Q14789,Q9HC07,Q9BTU6,Q8IWJ2,Q96A57
Localization
GO Cellular component
msigdb_gocc
522,268,272,660,275,283,669,34,429,688,430,53,185,61,694,63,578,445,69,456,327,463,465,599,605,734,470,505,229,358,360,106,236,753,369,116,507,761,121
864,34,578,470,463,106,2366,1221,63,1705,1961,2105,445,229,2916,53,275,360,1677,2722,669,1155,3065,2309,2792,1033,694,1181,1203,327,1085,2111,2638,1038,2660,1979,430,1055,1746,522,2589,1391,2115,605,2116,236,1424,456,1807,868,369,2779,61,465,505,599,2296,660,822,761,69,688,947,734,283,1271,1480,1663,358,121,272,777,236...
0.39013449402256833,2.605360668935537,0.7689615842364066,0.9432286304255554,0.9543830980982788,2.163357703140536,-0.5543007948494578,0.12175448251162654,2.346058243177083,-0.16014273539632354,-0.303787854117314,-0.3785188752723304,0.9765264378161742,1.6104756568747511,-1.1309875400384923,2.4355304023078563,1.4495286247...
3,193
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
13
32
2.916071
0.003545
P30519,O00767,Q32P28,O75592,O95864,Q14534,Q16850,Q6UW02,Q15800,O75845,P09601,P13674,P16435
Functions
GO Molecular function
msigdb_gomf
32,416,545,445,482,297,170,74,107,238,17,464,248
2134,416,1123,2000,1705,445,238,482,684,17,464,248,32,1975,2585,1534,1452,297,107,170,545,2088,1661,74,2766,2020,615,1043,2861,873,2394,1887
-0.39751866108604983,1.0416622545332883,0.1838925440088085,-0.32228307221127694,-0.16014273539632354,0.9765264378161742,1.5776579775269348,0.9320183829658302,0.5935493889180543,2.850934877568107,0.9543830980982788,1.5358542924197818,2.637217657100284,-0.303787854117314,-0.6988844633124501,-0.05719278632694883,-0.007169...
3,193
Abnormal chorioretinal morphology
13
27
2.915687
0.003549
Q8IY17,P40855,Q5XKP0,P52732,O75381,O43505,Q9Y619,Q10713,O60826,Q9NX14,P04439,P53701,P40939
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
640,386,260,509,263,262,267,236,582,530,275,317,631
999,262,1704,582,263,1468,2654,275,1128,386,631,1527,509,317,2375,1090,1391,236,964,260,2730,640,1063,649,530,267,1821
0.27435692511880505,1.4845046522176364,-0.16014273539632354,0.7568588077238091,1.4845046522176364,-0.023739075165896593,-0.7848314137948916,1.4495286247621895,0.1838925440088085,1.125611440557737,0.6703324293561015,-0.05719278632694883,0.8980485194817284,1.3033138565109923,-0.5543007948494578,0.21440615544338357,0.0256...
3,193
Abnormal choroid morphology
13
27
2.915687
0.003549
Q8IY17,P40855,Q5XKP0,P52732,O75381,O43505,Q9Y619,Q10713,O60826,Q9NX14,P04439,P53701,P40939
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
640,386,260,509,263,262,267,236,582,530,275,317,631
999,262,1704,582,263,1468,2654,275,1128,386,631,1527,509,317,2375,1090,1391,236,964,260,2730,640,1063,649,530,267,1821
0.27435692511880505,1.4845046522176364,-0.16014273539632354,0.7568588077238091,1.4845046522176364,-0.023739075165896593,-0.7848314137948916,1.4495286247621895,0.1838925440088085,1.125611440557737,0.6703324293561015,-0.05719278632694883,0.8980485194817284,1.3033138565109923,-0.5543007948494578,0.21440615544338357,0.0256...
3,193
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
10
28
2.91558
0.00355
P24390,O15258,Q9P2W9,Q12893,Q6NUQ1,Q9H4A6,P49755,Q9Y282,O43731,Q12981
Processes and pathways
GO Biological process
msigdb_gobp
2,355,39,456,483,268,304,119,26,223
844,2486,355,26,903,2213,2,1156,1081,1053,1602,304,2659,1390,1746,1057,456,574,223,483,871,734,1480,268,2061,39,2101,119
0.4042351666901161,-0.6360363435663436,1.1964900873490003,2.6816050945494077,0.34734463722339803,-0.4553008972742839,3.21572160468917,0.1684982022009186,0.21440615544338357,0.22952714396117282,-0.09107218097239303,1.3408498426869389,-0.7848314137948916,0.02566161901174243,-0.177690185818539,0.22952714396117282,0.965482...
3,193
Abnormal vascular physiology
13
47
2.908674
0.00363
Q6NUK1,P00403,O75844,P51798,P05067,Q14108,Q14739,P06280,P04062,Q9NWM8,Q9Y4P3,Q8IZA0,Q9NZ08
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
419,195,67,383,360,9,210,244,53,182,183,93,159
864,1123,1705,1789,2035,67,1520,195,1304,643,53,1356,360,244,1651,1652,981,3065,1333,2185,2760,1128,2603,1976,1084,383,656,2113,2318,1534,1092,9,2748,210,1771,493,419,93,947,1063,2206,182,159,2067,2480,183,1821
0.39013449402256833,0.1838925440088085,-0.16014273539632354,-0.213128942203161,-0.3409024311136362,2.329750012077,-0.05719278632694883,1.751667447018552,0.07415070895816572,0.6450133877649504,2.4355304023078563,0.04192461851956566,1.1865067348823226,1.5526815978228736,-0.12538587769838372,-0.12538587769838372,0.2891251...
3,193
Endomembrane system organization
63
167
2.905265
0.003669
Q96MW5,P50402,P61019,Q14108,P02545,Q6IAA8,O14964,Q9H4A6,Q9UQB8,Q8NHH9,Q7Z3C6,Q8N5M9,Q9BVK6,O95197,Q96GC9,O95295,A0FGR8,Q5J8M3,Q9P2W9,O43681,Q8TBA6,Q96A33,P61026,Q00765,P49755,P31751,Q9NQC3,Q15363,Q12907,P46459,P49257,O14578,O75844,O94901,P16615,Q14203,Q9BTV4,Q86XL3,O43760,O75955,O15027,P20700,Q8N1F7,O95721,Q9Y3B3,Q1298...
Processes and pathways
GO Biological process
msigdb_gobp
777,261,520,9,643,523,767,268,269,271,660,279,415,27,156,409,666,550,39,557,688,174,430,431,304,564,59,61,574,694,447,578,67,690,196,710,460,335,78,338,715,719,477,472,95,223,351,487,613,498,497,752,753,239,369,114,626,245,507,761,758,253,255
666,1889,2301,2302,1249,578,916,1646,2346,767,1331,715,245,2542,2905,557,78,919,2104,1961,2105,2348,903,1789,1047,67,338,690,2651,27,1647,409,472,643,1596,785,1387,196,2581,719,2309,2906,2138,564,1018,2356,1033,1180,866,1081,1736,351,694,940,447,304,261,1181,890,3161,1109,1086,255,2163,520,1130,430,941,758,2041,818,174...
0.6194206088649225,-0.2671646500903092,-0.51428752530657,-0.51428752530657,0.1059833465335269,0.7689615842364066,0.3329162614491058,-0.12538587769838372,-0.5342242617338631,0.48718206135466036,0.05808732403364699,0.5542099181825546,1.5442857407745552,-0.6777844648834328,-1.1066521830470757,0.8048943132507087,2.24572774...
3,193
Basolateral plasma membrane
17
42
2.903721
0.003688
Q14254,P08195,P35613,P20020,P11166,P55011,P05023,P02786,Q15043,Q9Y6M7,O75955,Q99808,P53985,Q12959,Q6P4Q7,P78310,P57105
Localization
GO Cellular component
msigdb_gocc
671,417,192,291,612,558,363,209,241,189,338,372,407,625,254,536,222
1383,999,338,1254,209,692,363,1676,1522,417,1559,612,1792,2008,1524,2284,1177,291,1827,833,1128,192,866,407,798,558,222,1568,536,1091,1424,2499,625,2438,1313,671,241,254,2534,372,189,2773
0.02566161901174243,0.27435692511880505,1.2359622824697312,0.1059833465335269,1.6979807301199143,0.5805078633245453,1.176476578042439,-0.14270834812699967,-0.05719278632694883,1.0416622545332883,-0.07407874008591195,0.7078077588474234,-0.213128942203161,-0.32228307221127694,-0.05719278632694883,-0.494489054305589,0.153...
3,193
Calcium ion transport
19
52
2.900454
0.003726
Q9UM00,P98194,P62942,Q96GC9,Q16611,P08195,P20020,Q8IYU8,Q9BPX6,P21796,O95202,Q9UJZ1,O75844,P16615,P30536,Q8WWC4,Q9HC07,O76024,P62258
Processes and pathways
GO Biological process
msigdb_gobp
385,522,276,156,544,417,291,425,301,51,190,577,67,196,200,357,116,247,633
1249,999,2488,1222,2072,67,247,190,1730,1676,1596,1522,1387,417,1792,2403,2352,196,1623,1501,291,51,3117,200,3091,1128,1081,1089,941,633,276,2378,522,1605,1423,2836,2193,1425,2381,544,2330,425,724,357,1400,156,898,301,116,577,385,677
0.1059833465335269,0.27435692511880505,-0.6360363435663436,0.12175448251162654,-0.3596472519831671,2.329750012077,1.5358542924197818,1.7667329517528663,-0.177690185818539,-0.14270834812699967,-0.09107218097239303,-0.05719278632694883,0.02566161901174243,1.0416622545332883,-0.213128942203161,-0.5745186791895069,-0.53422...
3,193
Monovalent inorganic cation homeostasis
15
29
2.892355
0.003824
Q8N511,Q15904,P50897,P06576,O75503,Q93050,P05023,Q9BXP2,Q9HC07,Q9Y5X3,Q9Y487,Q05086,Q9Y6M7,Q92544,O95295
Processes and pathways
GO Biological process
msigdb_gobp
161,323,8,552,139,208,363,433,116,373,88,503,189,353,409
139,409,1730,363,1676,552,2722,2906,2138,8,890,3161,798,558,1361,503,323,161,353,208,1063,433,116,2478,2151,88,373,2211,189
2.0123785518790727,1.05233382643295,-0.177690185818539,1.176476578042439,-0.14270834812699967,0.8167483885125356,-0.8509667351664257,-1.1066521830470757,-0.39751866108604983,3.0232917146470886,0.36168996784734275,-2.3972018839891502,0.45984406883424556,0.8048943132507087,0.04192461851956566,0.9094287765563077,1.2842897...
3,193
Amino acid transmembrane transport
11
13
2.8891
0.003863
O75746,P08195,Q96NB2,Q8TDW0,Q9UJS0,Q9Y619,O75915,Q9H936,O60831,Q9H9B4,Q15758
Processes and pathways
GO Biological process
msigdb_gobp
350,417,546,484,169,267,551,593,489,601,565
489,350,551,1078,417,565,484,546,705,593,601,169,267
0.9207519138862322,1.2064269794639189,0.8167483885125356,0.21440615544338357,1.0416622545332883,0.7929788244184839,0.9320183829658302,0.8402742865808962,0.5805078633245453,0.7446925671515504,0.7324623353077244,1.854681789652418,1.4758172511688186
3,193
Peptide metabolic process
125
414
3.08496
0.002036
P00374,P63220,P62263,O75821,O75874,P26373,O75503,Q9Y2L1,Q15046,P42892,Q02543,Q14011,P42574,P23588,Q969T7,P15880,P29692,P62750,P62244,P62241,Q9BSH4,Q15363,P05067,Q9Y3D3,O60506,O60841,Q9C0B1,P18621,P41252,P62277,P49207,Q07020,P61009,Q8WU90,P61254,P82930,Q9NVS2,Q9P2E9,P51114,Q9UI10,Q9UIQ6,O14773,P51116,P61927,P42766,P4959...
Processes and pathways
GO Biological process
msigdb_gobp
2,516,514,500,501,506,28,572,557,45,551,555,47,545,54,544,546,550,549,548,613,76,77,626,579,580,102,585,588,594,589,596,111,112,593,116,668,670,133,675,145,136,139,147,149,150,632,160,640,156,161,643,163,652,171,650,644,168,727,725,169,718,743,178,731,734,190,204,197,195,688,215,694,699,235,708,707,702,233,234,230,245,...
2907,1444,1099,2973,2067,1635,1842,136,1734,1021,2070,2455,3483,1954,2631,390,579,178,632,3345,580,875,1186,28,1187,1450,1452,500,1188,501,2459,877,466,3606,1274,3307,2081,2,688,2854,957,746,168,77,882,195,2716,410,1861,884,1648,1966,1369,2368,230,2560,470,817,1194,1195,1650,1284,1371,2184,544,438,3442,245,585,2186,137...
-0.5300158691897872,0.13497055902126676,0.29456889269544306,-0.5729515086483371,-0.10945505514571849,0.05417132380796351,-0.02730624012991288,1.48941744476724,0.013516920484463254,0.3340648152239322,-0.10945505514571849,-0.27573700123213735,-1.4635939304590377,-0.06829720991097807,-0.3598559520850405,0.8339285658166788...
3,643
Peptide biosynthetic process
109
366
3.054392
0.002255
P00374,P63220,P62263,O75821,P26373,Q9Y2L1,Q15046,Q02543,Q14011,P23588,Q969T7,P15880,P29692,P62750,P62244,P62241,Q9BSH4,Q15363,P05067,Q9Y3D3,O60506,O60841,Q9C0B1,P18621,P41252,P62277,P49207,Q07020,Q8WU90,P61254,P82930,Q9NVS2,Q9P2E9,P51114,Q9UI10,P51116,P61927,P42766,P49590,O60573,Q9Y3U8,P61247,P46778,P35268,Q04637,P6284...
Processes and pathways
GO Biological process
msigdb_gobp
2,516,514,500,506,572,557,551,555,545,54,544,546,550,549,548,613,76,77,626,579,580,102,585,588,594,589,596,112,593,116,668,670,133,675,139,147,149,150,632,160,640,156,161,643,163,652,650,644,168,727,725,169,718,743,178,731,734,190,197,195,215,694,699,235,708,707,702,234,700,245,260,285,280,276,275,309,313,324,325,355,3...
2907,1444,1099,2067,1635,1842,1734,1021,2070,3483,1954,2631,390,579,178,632,3345,580,875,1186,1187,1452,500,1188,2459,3606,1274,2081,2,957,746,168,77,882,195,2716,410,1861,884,1648,1966,1369,2368,470,817,1194,1195,1650,1371,2184,544,438,3442,245,585,2186,1374,962,1974,2375,395,545,2090,366,2473,506,1039,694,1975,3203,3...
-0.5300158691897872,0.13497055902126676,0.29456889269544306,-0.10945505514571849,0.05417132380796351,-0.02730624012991288,0.013516920484463254,0.3340648152239322,-0.10945505514571849,-1.4635939304590377,-0.06829720991097807,-0.3598559520850405,0.8339285658166788,0.6062504027368125,1.2752051474731445,0.5678121408781559,...
3,643
Tchem
92
370
2.665999
0.007676
P42785,P63151,O00754,Q13126,O75874,Q9H7B4,P11766,Q5BJF2,P49327,P07099,Q8NCG7,P45880,Q92820,Q96B36,Q15046,P42892,P30519,P42574,O14936,P25098,P06737,Q8WTV0,O60502,Q01433,Q86U86,Q86X55,P05067,Q9UPP1,Q9H773,Q9UBM7,P10619,P41252,Q13535,Q06124,Q02818,Q00796,Q9UIQ6,P07384,P09601,O14733,Q13526,P04062,O15382,O60725,P48449,P4349...
Drugs and Diseases
Pharos IDG Category
pharos_protein_category
1,515,497,9,501,14,503,16,512,21,562,29,564,36,557,45,46,47,538,52,542,61,65,66,604,605,77,624,85,86,583,588,598,595,118,141,145,138,155,153,171,167,165,179,181,211,209,237,232,230,229,228,246,268,259,256,288,271,270,304,291,295,289,302,294,300,329,320,342,341,375,381,363,362,364,368,369,398,406,429,412,410,452,448,439...
1180,1546,1547,1842,497,1548,1843,153,341,289,1101,2550,538,2068,806,1102,3548,3117,684,1551,1952,1364,3482,165,2713,1736,2282,270,271,342,2074,65,1272,179,1638,1025,3157,2914,501,3398,2287,1106,3120,3373,1275,2983,1962,2786,956,1456,2464,1643,3637,167,3070,1859,3022,957,2984,746,77,228,2181,362,410,2557,542,229,21,196...
0.25491371452005795,0.09465600693820425,0.09465600693820425,-0.02730624012991288,0.6826983338672731,0.09465600693820425,-0.02730624012991288,1.3828179266851532,0.9087374424306347,0.9830256571422673,0.29456889269544306,-0.3177156982737179,0.6445452047790015,-0.10945505514571849,0.4516181396968097,0.29456889269544306,-1....
3,643
Cellular responses to stimuli
103
353
2.573826
0.010058
Q9Y5K8,P63220,Q15008,P62263,P26373,P49721,P28072,P10412,Q96B36,Q9Y2L1,Q14203,Q02543,P30519,O43242,P15880,P62750,P62244,P62241,Q86X55,Q9BSH4,Q7Z5J4,P28070,P30043,P18621,P62277,P49207,Q13535,Q07020,P61254,Q16763,Q9BTX1,Q92530,Q8NFH4,P60900,O14773,P61927,Q15185,P42766,Q969H8,Q9Y3U8,P09601,P46778,P61247,O14733,P35268,P6284...
Processes and pathways
Reactome Pathways
msigdb_reactome
534,516,517,514,506,17,507,24,36,572,556,551,46,539,544,550,549,548,605,613,83,88,587,585,594,589,598,596,593,120,135,144,656,140,136,147,148,149,151,160,155,156,640,153,161,163,647,176,722,727,185,182,190,738,195,688,215,695,691,699,708,239,704,702,234,700,232,778,252,791,245,244,800,260,745,746,753,751,758,324,325,35...
1100,2909,2276,2709,1951,2279,3577,153,136,1549,807,2281,539,361,1553,1023,343,1185,2911,3346,1025,3157,1451,2980,2460,2553,467,2784,1961,878,2081,745,2785,2786,688,2290,2787,2854,1277,2984,746,882,195,2716,2181,1110,1111,1458,1190,2367,691,1966,1369,155,244,2468,24,1557,1281,411,817,3123,1561,2298,544,1651,2790,1562,1...
0.29456889269544306,-0.5300158691897872,-0.19226770706505575,-0.40215692054232677,-0.06829720991097807,-0.19226770706505575,-2.2175622857850827,1.3828179266851532,1.48941744476724,0.09465600693820425,0.4516181396968097,-0.19226770706505575,0.6445452047790015,0.8713988558774409,0.09465600693820425,0.3340648152239322,0.9...
3,643
Alcohol binding
6
19
2.511685
0.012016
Q14108,P21796,O15118,P45880,O14735,Q14849
Functions
GO Molecular function
msigdb_gomf
13,15,48,29,207,60
207,48,2975,2912,2917,2920,15,1566,820,439,698,29,2932,13,2493,60,3333,1625,286
1.1665459322940055,2.570770098965035,-0.5729515086483371,-0.5300158691897872,-0.5300158691897872,-0.5300158691897872,4.697366544048904,0.09465600693820425,0.4516181396968097,0.7585865338726075,0.5292285936168137,3.3256950141393116,-0.5300158691897872,4.725249991921275,-0.27573700123213735,2.3421857971160014,-1.01080062...
3,643
Amide biosynthetic process
118
405
2.451972
0.014208
P00374,P63220,P62263,O75821,P26373,P50897,Q9UMR5,Q9Y2L1,Q96G23,Q15046,Q02543,Q14011,P23588,Q969T7,P15880,P29692,P62750,P62244,P62241,Q9BSH4,Q15363,P05067,Q9Y3D3,O60506,O60841,Q9C0B1,P18621,P41252,P62277,P49207,Q07020,Q8WU90,P61254,P82930,Q9NVS2,Q9P2E9,P51114,Q9UI10,P51116,P61927,P42766,P49590,O60573,Q9Y3U8,P61247,P4677...
Processes and pathways
GO Biological process
msigdb_gobp
2,516,514,500,506,34,35,572,41,557,551,555,545,54,544,546,550,549,548,613,76,77,626,579,580,102,585,588,594,589,596,112,593,116,668,670,133,675,139,147,149,150,632,160,640,156,161,643,163,652,650,644,168,167,727,725,169,718,743,178,731,734,190,197,195,215,694,691,698,699,235,708,707,702,234,700,245,260,285,280,276,275,...
2907,1444,1099,2067,1635,1842,1548,3548,1551,1952,1734,1021,2070,3483,1954,2631,390,2075,579,178,632,3345,580,875,1186,1187,1450,1452,500,1188,2459,3606,1274,2081,2555,1745,2,167,957,746,168,77,882,195,2716,410,1861,884,691,2293,1648,1966,1369,2368,3024,2986,1969,470,817,1194,1195,1650,1371,2184,544,438,3442,245,585,21...
-0.5300158691897872,0.13497055902126676,0.29456889269544306,-0.10945505514571849,0.05417132380796351,-0.02730624012991288,0.09465600693820425,-1.9306856680737758,0.09465600693820425,-0.06829720991097807,0.013516920484463254,0.3340648152239322,-0.10945505514571849,-1.4635939304590377,-0.06829720991097807,-0.359855952085...
3,643
Transsulfuration and onecarbon metabolism
6
19
2.423457
0.015374
P00374,O43865,P04818,P31153,P42898,P23526
Processes and pathways
WikiPathways
msigdb_wp
2,342,168,292,210,209
3016,342,2,168,2085,885,209,505,292,894,1573,210,1662,3127,1580,1505,1819,1939,1949
-0.6160438250868361,0.9087374424306347,6.3179115988383705,1.3111906687344248,-0.10945505514571849,0.41258737723718314,1.1665459322940055,0.6826983338672731,0.9830256571422673,0.41258737723718314,0.09465600693820425,1.1665459322940055,0.05417132380796351,-0.7026954003659576,0.09465600693820425,0.13497055902126676,0.0135...
3,643
Protease inhibitor
6
11
2.421807
0.015444
P11047,P30086,Q92530,P05067,P27105,P98170
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
437,5,144,77,323,482
469,77,437,323,5,2930,1986,482,144,2603,2445
0.7207115392909282,2.008261432781888,0.7585865338726075,0.9459458711683172,5.9074558563010005,-0.5300158691897872,-0.06829720991097807,0.7207115392909282,1.48941744476724,-0.3177156982737179,-0.23392071524847363
3,643
Regulation of blood pressure
8
20
2.270496
0.023178
P42785,P09493,Q9UIQ6,P11766,Q9NZ08,P42892,Q9HB40,P09601
Processes and pathways
GO Biological process
msigdb_gobp
1,321,145,503,288,45,18,155
2287,2854,2465,321,155,503,504,1,45,758,3377,2310,3289,2805,1076,1089,18,288,145,2274
-0.19226770706505575,-0.48723769204762063,-0.27573700123213735,0.9459458711683172,1.3828179266851532,0.6826983338672731,0.6826983338672731,6.941235345355567,2.667506925248244,0.4904978954465923,-1.10018555437503,-0.19226770706505575,-0.9220131979581028,-0.4446177734057036,0.3340648152239322,0.3340648152239322,4.2730493...
3,643
Infectious disease
116
378
2.20183
0.027677
P63220,Q99720,Q15008,P62263,P26373,P49721,P28072,P46108,Q9UQB8,Q02543,Q13263,O43242,P15880,P62750,P62244,P62241,P29084,P05067,P28070,O43747,P18621,P51948,P14314,P62277,P49207,Q07020,P61254,P54709,Q92747,Q9BTX1,Q92530,Q8NFH4,P60900,Q86VN1,P61927,Q15185,P42766,Q9Y3U8,P30876,P09601,P46778,P61247,O14733,P35268,P62841,Q9Y6W...
Processes and pathways
Reactome Pathways
msigdb_reactome
516,3,517,514,506,17,507,511,26,551,554,539,544,550,549,548,70,77,88,578,585,104,106,594,589,596,593,591,658,135,144,656,140,655,147,148,149,160,637,155,156,640,153,161,163,164,651,174,647,718,182,190,195,689,215,693,695,699,710,709,708,702,234,700,786,784,783,252,791,245,262,260,257,749,750,753,758,269,762,312,297,299...
1098,1100,2909,2276,1363,947,3591,1951,269,153,1549,807,3198,3068,2070,1271,2281,539,578,342,2074,1850,1638,875,1025,1741,3157,3578,1451,2980,2981,468,1960,1746,3347,2464,1277,689,2291,2637,2292,2465,3374,77,2788,195,2716,2985,2181,2557,1861,2466,1458,1646,3023,1190,1966,1967,1369,2183,155,1034,1749,3452,3072,1752,817,...
0.29456889269544306,0.29456889269544306,-0.5300158691897872,-0.19226770706505575,0.17511680853070935,0.3734036151295807,-2.411501085055282,-0.06829720991097807,1.0199782856151238,1.3828179266851532,0.09465600693820425,0.4516181396968097,-0.7899645203664171,-0.6592920437768817,-0.10945505514571849,0.21509709788496337,-0...
3,643
Postural tremor
8
20
2.173698
0.029728
O75569,P35637,Q14108,O75306,O14773,Q9H6K4,Q06787,P03886
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
465,107,13,225,136,220,374,94
136,683,225,465,2554,2080,94,1277,2718,107,1481,374,13,3004,2039,1818,220,3369,570,1094
1.48941744476724,0.5292285936168137,1.1300876488525198,0.7207115392909282,-0.3177156982737179,-0.10945505514571849,1.8034426544617923,0.21509709788496337,-0.40215692054232677,1.6997007641594284,0.13497055902126676,0.8713988558774409,4.725249991921275,-0.5729515086483371,-0.06829720991097807,0.013516920484463254,1.16654...
3,643
Protein k63 linked ubiquitination
10
17
2.142075
0.032187
Q96J02,Q63HN8,P61088,Q9ULT8,Q9UNE7,Q16763,Q9Y263,P19474,Q9C0C9,Q96FW1
Processes and pathways
GO Biological process
msigdb_gobp
333,328,901,679,1094,120,869,87,490,989
1842,1027,1642,2370,87,901,2001,2494,120,328,989,333,490,679,2267,1094,869
-0.02730624012991288,0.3340648152239322,0.05417132380796351,-0.23392071524847363,1.837822692730858,0.41258737723718314,-0.06829720991097807,-0.27573700123213735,1.630028026177886,0.9459458711683172,0.3734036151295807,0.9459458711683172,0.7207115392909282,0.5678121408781559,-0.1507788561777983,0.3340648152239322,0.45161...
3,643
Cellular amide metabolic process
143
495
2.129262
0.033233
P00374,P63220,P62263,Q8NCC3,O75821,O75874,P26373,O75503,P50897,Q9UMR5,Q9Y2L1,Q96G23,Q15046,P42892,Q02543,Q14011,P42574,P23588,Q969T7,P15880,P29692,P62750,P62244,P62241,Q9BSH4,Q15363,P05067,Q9Y3D3,O60506,O60841,Q9C0B1,P18621,P41252,P62277,P49207,Q07020,P61009,Q8WU90,P61254,P82930,Q9NVS2,Q9P2E9,P51114,Q9UI10,Q9UIQ6,O1477...
Processes and pathways
GO Biological process
msigdb_gobp
2,516,514,8,500,501,506,28,34,35,572,41,557,45,551,555,47,545,54,544,546,550,549,548,613,76,77,626,579,580,102,585,588,594,589,596,111,112,593,116,668,670,133,675,145,136,139,147,149,150,632,160,640,156,161,643,163,652,171,650,644,168,167,727,725,169,187,718,743,178,177,731,734,190,204,742,197,195,688,215,694,691,698,6...
2907,1444,177,1099,2973,2067,1635,1842,1548,3116,136,3548,1551,1952,1734,1021,2070,2455,3483,1954,2631,390,2075,579,178,632,3345,580,875,1186,28,1187,1450,1452,500,1188,501,2459,877,466,3606,1274,3307,2081,1275,2555,1745,2,688,2853,3159,167,2854,957,2984,746,168,77,882,195,2716,274,410,1861,229,3236,884,691,2293,1648,1...
-0.5300158691897872,0.13497055902126676,1.2752051474731445,0.29456889269544306,-0.5729515086483371,-0.10945505514571849,0.05417132380796351,-0.02730624012991288,0.09465600693820425,-0.7026954003659576,1.48941744476724,-1.9306856680737758,0.09465600693820425,-0.06829720991097807,0.013516920484463254,0.3340648152239322,-...
3,643
Mucosal telangiectasiae
6
11
2.122507
0.033795
Q8IZA0,P10619,Q92889,P19447,P06280,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,583,611,257,274,96
274,583,1751,888,257,2373,597,96,2807,32,611
1.0199782856151238,0.6062504027368125,0.013516920484463254,0.41258737723718314,1.056805212881239,-0.23392071524847363,0.6062504027368125,1.8034426544617923,-0.4446177734057036,3.1718471218172124,0.6062504027368125
3,643
Golgi apparatus
56
336
2.121762
0.033858
Q9UBF8,Q9BZH6,Q9BQA1,P24390,Q15334,Q9Y282,Q14108,Q9GZZ9,O14773,Q969H8,Q9UQB8,P06280,O75503,Q8IZA0,Q8NCM8,P50897,Q8NB49,Q15392,P35613,Q96PU5,Q8N1B4,Q9BXS5,P04062,O15118,P80303,Q12907,O43505,Q99805,Q15036,Q04721,O15258,Q92542,Q15363,P20645,P05067,O15127,O15027,Q7Z5K2,Q14677,P82094,Q8IUD2,O14735,P48739,Q9UHD1,P49755,O4390...
Localization
GO Cellular component
msigdb_gocc
268,267,266,4,264,12,13,287,136,151,26,274,28,32,33,34,307,37,39,174,173,312,167,48,49,183,51,187,184,300,189,204,76,196,77,78,317,84,326,216,356,207,212,242,346,343,341,223,108,222,384,385,123,376,363,118
2065,2168,3258,1546,629,1547,222,1844,1636,3577,871,207,341,136,1182,806,317,48,388,78,189,462,3482,1845,2455,2848,2910,1737,51,578,631,1738,873,343,223,2714,3019,2851,2633,28,1187,1450,1961,3307,3373,1107,2080,502,1745,2715,1746,1643,3637,167,689,2465,77,274,1111,1646,3023,1967,2183,1968,3071,1112,1750,363,886,3375,13...
-0.10945505514571849,-0.1507788561777983,-0.8778452693963296,0.09465600693820425,0.5678121408781559,0.09465600693820425,1.1300876488525198,-0.02730624012991288,0.05417132380796351,-2.2175622857850827,0.41258737723718314,1.1665459322940055,0.9087374424306347,1.48941744476724,0.25491371452005795,0.4516181396968097,0.9459...
3,643
Glycosaminoglycan metabolism
8
15
2.104716
0.035316
Q9UHD1,P06865,P15586,P08236,O43505,Q8TB61,O75330,P54802
Processes and pathways
Reactome Pathways
msigdb_reactome
242,229,44,320,51,376,208,62
389,51,208,1028,229,3236,320,44,886,62,3586,1079,376,2034,242
0.8339285658166788,2.5383635486138947,1.1665459322940055,0.3340648152239322,1.1300876488525198,-0.8338288049592498,0.9459458711683172,2.667506925248244,0.41258737723718314,2.3091930241401677,-2.3142656298623137,0.3340648152239322,0.8713988558774409,-0.06829720991097807,1.1300876488525198
3,643
Glycoside hydrolase superfamily [IPR017853]
6
17
2.083468
0.037209
O60502,P10253,P06865,P04062,P06280,P54802
Sequence
InterPro Superfamily
interpro_homologous_superfamily
65,132,229,167,274,62
65,167,3070,274,229,3236,1647,320,132,886,697,62,2203,1788,3502,1526,1624
2.209691409571193,1.3111906687344248,-0.6592920437768817,1.0199782856151238,1.1300876488525198,-0.8338288049592498,0.05417132380796351,0.9459458711683172,1.5247309273550007,0.41258737723718314,0.5292285936168137,2.3091930241401677,-0.1507788561777983,0.013516920484463254,-1.555887732745047,0.13497055902126676,0.0946560...
3,643
Ovoid vertebral bodies
6
9
2.003044
0.045173
Q9Y3A5,P15586,P49585,Q5F1R6,Q99575,P54802
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
739,44,755,602,186,62
44,886,755,62,1386,602,2034,186,739
2.667506925248244,0.41258737723718314,0.4904978954465923,2.3091930241401677,0.17511680853070935,0.6062504027368125,-0.06829720991097807,1.2752051474731445,0.5292285936168137
3,643
Sensory perception of light stimulus
7
18
1.990259
0.046562
Q6P4Q7,P50897,P11047,O76024,Q9H6K4,Q15555,P53611
Processes and pathways
GO Biological process
msigdb_gobp
306,34,437,467,220,119,157
2366,465,467,1859,437,2791,34,157,711,1311,119,306,1610,2754,3093,220,3323,1355
-0.23392071524847363,0.7207115392909282,0.7207115392909282,-0.02730624012991288,0.7585865338726075,-0.4446177734057036,3.078707997499416,1.3828179266851532,0.5292285936168137,0.21509709788496337,1.630028026177886,0.9830256571422673,0.09465600693820425,-0.40215692054232677,-0.6592920437768817,1.1665459322940055,-0.96633...
3,643
Preaxial hand polydactyly
6
13
1.972477
0.048555
Q8NCM8,O43909,Q96EX3,O96028,Q5H8A4,Q9UHX1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,343,330,103,218,456
343,1855,103,1895,2006,218,33,330,3465,1712,2833,456,624
0.9087374424306347,-0.02730624012991288,1.7343826773873927,-0.02730624012991288,-0.06829720991097807,1.1665459322940055,3.1098247993659944,0.9459458711683172,-1.3718718400106042,0.05417132380796351,-0.4446177734057036,0.7585865338726075,0.6062504027368125
3,643
Lysosome
27
56
3.903037
0.000095
Q14108,O15118,P10253,O14773,P54802,O75503,Q8NCC3,P06280,P16278,P11717,P20645,Q9Y487,P15586,Q8NHS3,P10619,O00754,P07602,P50897,Q9UMR5,Q93050,P08236,P04066,Q15012,P61916,Q99523,P11117,O43681
Processes and pathways
KEGG Pathways
msigdb_kegg
255,252,266,391,147,24,28,153,155,154,37,43,410,52,59,435,69,72,77,82,455,228,353,351,114,236,118
2321,1952,435,2792,391,252,118,2860,24,703,228,153,1013,69,3538,455,1702,1703,266,59,236,1082,154,2332,410,155,2869,37,707,3578,72,1632,147,2768,2587,351,3571,952,1160,3473,255,353,965,28,52,2014,82,114,520,1933,1064,2401,3008,77,1436,43
-0.2609563355332265,-0.13054795621506413,0.7224199472328477,-0.4920008457387619,0.7838890695289682,1.08805639508316,1.7982903969638317,-0.525313577596298,4.11230346222967,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,2.427791890653298,-1.3862754857551036,0.6916031594494587,-0.03347806686...
3,643
SLC superfamily of solute carriers
28
55
3.723241
0.000197
Q9BSK2,Q86VD7,Q9HC07,Q96H78,Q6NT16,Q8IXU6,O43772,Q01650,Q7L0J3,Q9HC21,Q9Y619,Q9Y666,Q9Y6C9,Q8N1S5,P11166,O00400,Q70HW3,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,Q15758,P30825,P55011,Q9H2D1,P41440,Q9Y6M7
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
260,256,405,274,10,12,13,143,17,553,693,694,695,671,279,646,285,152,306,577,44,573,662,54,440,733,90,361
646,13,2754,1450,1372,152,1962,1873,704,279,2331,1145,54,90,2073,44,440,2812,143,2771,963,662,2274,1657,10,2366,3456,285,17,256,12,671,3525,573,1502,274,2906,2907,2292,577,260,2115,733,1350,1057,405,553,1064,306,924,2788,693,694,695,361
0.47430803058067816,5.243267115697605,-0.4587663248239629,0.06298071889501843,0.09500082791205905,1.5350292358486646,-0.13054795621506413,-0.098122333905974,0.44303477605405855,1.027635769907882,-0.2609563355332265,0.19067127264620573,2.707887319665007,2.058127752852981,-0.16304347134508207,3.1215736355280526,0.7224199...
3,643
Vacuolar membrane
34
147
3.565765
0.000363
Q14108,P42785,O15118,Q8WTV0,Q9HD42,P30511,Q01650,P10253,O75503,Q8TCT8,P20645,Q9UIQ6,Q9Y487,Q07065,O75787,O14678,Q9BXS4,Q8NHS3,P42892,Q92542,P10619,P07602,Q8IV08,P55735,Q93050,P41440,Q9NRA0,O15260,Q99523,P15291,P11117,O75955,Q9NQX7,Q9NUN5
Localization
GO Cellular component
msigdb_gocc
255,4,252,8,276,138,143,266,24,158,37,42,43,173,296,176,50,52,53,317,59,69,73,201,82,90,227,108,114,112,236,249,122,123
1952,2792,176,252,108,586,2963,2860,1138,2700,1078,24,296,249,2798,1456,2507,2328,3617,703,3104,3191,69,3106,704,1457,2057,1702,266,59,3219,236,2144,1082,2332,112,37,2061,3422,2927,563,2580,138,2873,312,1624,2661,3200,90,1086,4,53,1628,1300,2156,459,3607,460,476,2348,201,2768,2717,2586,2075,2587,3571,2251,1636,952,143,...
-0.13054795621506413,-0.4920008457387619,1.446478167816503,1.08805639508316,1.914184390727662,0.5366787829519797,-0.5921770650124923,-0.525313577596298,0.19067127264620573,-0.42560918711049844,0.2224334357534765,4.11230346222967,0.9973494401983068,1.118191455601226,-0.4920008457387619,0.06298071889501843,-0.32659402529...
3,643
Lysosomal lumen
21
37
3.383474
0.000716
Q14108,P10253,O14773,P54802,Q9UM22,P06280,P16278,P15586,Q8NHP8,P10619,O00754,P07602,Q8IV08,P50897,Q9UMR5,P08236,P04066,O00584,P61916,P11117,O43681
Localization
GO Cellular component
msigdb_gocc
255,266,391,147,22,153,155,410,58,59,435,69,73,72,77,455,228,103,351,236,118
103,435,391,118,703,228,153,1013,69,3538,1789,455,266,59,236,2144,2332,410,155,2869,707,847,3578,2432,72,147,351,3473,255,73,1663,58,520,3002,1064,22,77
1.943054324684516,0.7224199472328477,0.7838890695289682,1.7982903969638317,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,2.427791890653298,-1.3862754857551036,-0.06576592628969985,0.6916031594494587,1.0578712931665288,2.5402599154147643,1.1482768495977804,-0.19560956934146895,-0.26095633...
3,643
Peptidase activity
37
124
3.370601
0.00075
P42785,Q4J6C6,Q9HD42,P20618,O14773,P28072,Q8TCT8,P60900,P55786,Q9HB40,Q9UIQ6,P28070,P28074,P02786,Q9BXS4,P42892,Q92542,P10619,P49721,P22695,O75976,O15484,P78536,Q9H300,Q9H3G5,Q96K76,P52888,Q9NQH7,P17655,Q9NZ08,Q93009,Q16740,Q9BT78,Q99538,Q99436,O75844,Q9UPT9
Functions
GO Molecular function
msigdb_gomf
4,135,276,137,391,146,158,283,31,35,42,164,41,409,50,53,317,59,60,311,206,209,216,491,359,485,98,386,473,245,481,113,385,520,121,248,124
745,1135,391,1212,209,2216,1137,2137,248,206,2052,2327,2966,885,409,2864,3151,2222,59,3108,3109,2760,473,137,311,2802,164,146,41,3323,2659,3030,1544,1973,1019,4,53,1977,3201,2878,60,3298,1229,1631,98,1980,1554,1632,1888,31,283,2245,2254,216,3614,2355,2883,658,3347,803,2773,2361,2986,113,1652,135,2891,1042,3085,3045,277...
0.4117022638315761,0.19067127264620573,0.7838890695289682,0.15884550726049723,1.268129085929357,-0.22824695247054547,0.19067127264620573,-0.19560956934146895,1.118191455601226,1.2979715997804608,-0.16304347134508207,-0.2609563355332265,-0.5921770650124923,0.31734400267200297,0.7531817696547146,-0.525313577596298,-0.726...
3,643
Action tremor
21
60
3.319455
0.000902
Q99720,Q14108,O75027,O14773,Q9NR77,O75787,Q9H6K4,Q9BUB7,P03886,P20700,P07602,Q15233,P00846,Q9Y4W6,Q9Y448,P41440,O75569,O75306,Q01082,O43681,Q9NQH7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,255,21,391,32,296,579,447,62,310,69,567,74,608,348,90,350,471,365,118,386
1862,391,1210,2571,118,21,471,350,296,791,1782,2705,74,62,2967,2758,2654,69,1874,2925,1222,2225,310,1293,3028,592,1971,754,90,2877,1885,2242,1088,1387,365,955,255,567,1042,2452,3491,1407,3393,859,1664,2622,1675,3177,2,2112,447,579,386,32,1064,1521,2562,3286,348,608
-0.098122333905974,0.7838890695289682,0.15884550726049723,-0.3595238272390506,1.7982903969638317,4.373525061543824,0.6607309570482511,0.8756881681175116,0.9973494401983068,0.3803099800917596,-0.06576592628969985,-0.42560918711049844,2.371337868662573,2.512197372488192,-0.5921770650124923,-0.4587663248239629,-0.39252862...
3,643
Predicted secreted proteins
19
64
3.256048
0.00113
P07942,Q08380,P14174,Q9UM22,Q9UMX5,P05067,Q9HB40,P22466,O75718,Q8WUJ1,Q8NDZ4,Q02818,P43490,Q9H9S5,P80303,O00584,Q9NZ08,Q15165,Q9BTY2
Functions
Protein Atlas Protein class
protein_atlas_protein_class
126,254,15,22,27,29,35,38,295,49,63,65,71,347,93,103,245,109,115
103,1606,1958,649,295,749,2138,1787,409,2508,29,2509,3191,126,1081,1704,3257,15,2760,1084,38,2516,616,3407,71,2584,2521,3515,351,2162,93,3614,657,65,1310,254,2082,1993,1031,109,2776,3592,1574,1744,676,3593,63,49,1182,468,677,2950,3560,115,3553,488,3554,2029,347,35,245,22,27,1603
1.943054324684516,-0.0012581004565036626,-0.13054795621506413,0.47430803058067816,0.9973494401983068,0.4117022638315761,-0.19560956934146895,-0.06576592628969985,0.7531817696547146,-0.3265940252928932,3.6353042018995785,-0.3265940252928932,-0.7607655898218467,1.7109272480905777,0.2224334357534765,-0.03347806686168351,-...
3,643
Abnormality of peripheral nerves
11
51
3.224761
0.001261
Q9NR77,Q99720,P07602,O95831,P02545,Q71SY5,P39210,O43681,Q9GZY8,P07196,Q00796
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,2,69,47,265,144,267,118,130,125,156
746,2212,118,1776,791,1456,47,265,125,69,1878,1222,1713,2711,267,2662,890,1467,1800,1155,2156,2238,2242,2349,3408,3471,156,3328,2087,2091,627,1825,2946,144,464,300,859,2734,813,2612,1675,1053,2,130,3533,32,1064,3243,1521,1767,693
0.4117022638315761,-0.22824695247054547,1.7982903969638317,-0.06576592628969985,0.3803099800917596,0.06298071889501843,3.0119856905575273,1.0578712931665288,1.7400910153055076,2.427791890653298,-0.098122333905974,0.15884550726049723,-0.03347806686168351,-0.42560918711049844,1.0578712931665288,-0.3925286203228279,0.3173...
3,643
Organic acid transport
15
53
3.216902
0.001296
P11166,O95563,Q9UBX3,P23786,Q96H78,P80404,O43772,P53985,P14174,Q01650,Q7L0J3,O14678,P31751,P30825,P41440
Processes and pathways
GO Biological process
msigdb_gobp
279,152,306,200,274,413,13,44,15,143,17,176,364,54,90
176,2793,2049,1003,13,2754,2219,1450,3068,152,1286,2653,2508,3218,1874,1374,704,279,15,200,1622,54,592,364,1224,2342,90,3264,2073,44,440,413,143,2771,1317,765,662,3456,719,17,1177,2829,274,2906,2907,577,733,1057,306,924,1764,874,693
1.446478167816503,-0.4920008457387619,-0.16304347134508207,0.25413257026133235,5.243267115697605,-0.4587663248239629,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,0.12695555655645674,-0.3925286203228279,-0.3265940252928932,-0.7947358122572576,-0.098122333905974,0.09500082791205905,0.44...
3,643
Molecular transducer activity
18
41
3.184449
0.00145
P11717,Q99720,Q14108,Q4VCS5,P20645,O15118,Q9P2E9,Q8WTV0,P22466,O15173,Q15629,O75787,Q9NWH9,Q5KU26,Q15375,Q99523,P10586,Q9NRA0
Functions
GO Molecular function
msigdb_gomf
154,2,255,512,37,252,407,8,38,199,509,296,371,396,418,114,119,227
1606,1072,252,199,3495,296,3218,1012,119,154,942,37,38,3615,1296,1976,2236,2669,1893,1395,1993,255,418,509,662,512,396,3305,8,2103,547,114,2,3056,227,371,407,991,1593,3432,877
-0.0012581004565036626,0.2224334357534765,1.08805639508316,1.327766595224347,-1.244601121096576,0.9973494401983068,-0.7947358122572576,0.25413257026133235,1.7982903969638317,1.5350292358486646,0.2857692407025649,3.284999162596966,3.257840018273795,-2.2291720974867153,0.12695555655645674,-0.13054795621506413,-0.22824695...
3,643
Vacuolar lumen
23
69
3.182698
0.001459
Q14108,P78371,P10253,O14773,P54802,Q9UM22,P06280,P16278,P15586,Q8NHP8,P10619,O00754,P07602,Q8IV08,P50897,Q9UMR5,P08236,P04066,O00584,P61916,Q9BTY2,P11117,O43681
Localization
GO Cellular component
msigdb_gocc
255,378,266,391,147,22,153,155,410,58,59,435,69,73,72,77,455,228,103,351,115,236,118
2322,103,435,391,118,2704,703,228,153,1013,3191,1701,69,3538,1789,455,266,59,236,2144,1964,2332,410,155,2869,3294,3197,3324,707,847,3578,2432,2935,72,2237,1805,1632,1806,147,2349,1023,351,2161,378,2813,2938,1238,3473,255,2087,73,1663,58,1417,1835,1507,2111,520,683,115,3002,3211,2693,2202,1064,22,77,2492,609
-0.2609563355332265,1.943054324684516,0.7224199472328477,0.7838890695289682,1.7982903969638317,-0.42560918711049844,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,-0.7607655898218467,-0.03347806686168351,2.427791890653298,-1.3862754857551036,-0.06576592628969985,0.6916031594494587,1.05787...
3,643
Endopeptidase activity
24
70
3.168755
0.001531
Q4J6C6,P20618,O14773,P28072,Q8TCT8,P60900,P28070,P28074,Q9BXS4,P42892,Q92542,P49721,P22695,O15484,P78536,Q9H300,Q96K76,P52888,P17655,Q9NZ08,Q93009,Q16740,Q99436,O75844
Functions
GO Molecular function
msigdb_gomf
135,137,391,146,158,283,164,41,50,53,317,60,311,209,216,491,485,98,473,245,481,113,121,248
391,209,2216,1137,2137,248,2327,2864,3151,3109,2760,473,137,311,2802,164,146,41,2659,3030,1973,1019,53,1977,3201,2878,60,1631,98,1632,1888,283,2254,216,658,803,2773,2361,113,1652,135,1042,3085,3045,2776,601,2989,675,158,3492,317,1921,3133,2378,481,485,730,1264,121,520,2737,3179,50,1422,491,245,2638,1132,1769,608
0.7838890695289682,1.268129085929357,-0.22824695247054547,0.19067127264620573,-0.19560956934146895,1.118191455601226,-0.2609563355332265,-0.525313577596298,-0.726880811724572,-0.6930805097254553,-0.4587663248239629,0.6607309570482511,1.623176179314646,0.9670119136618348,-0.4920008457387619,1.5055575321040489,1.56445603...
3,643
Protease
27
89
3.077885
0.002085
P42785,Q4J6C6,O14773,P28072,Q8TCT8,P55786,Q9HB40,Q9UIQ6,P28074,P42892,P10619,O75976,O15484,P78536,Q9H300,Q9H3G5,Q96K76,P52888,Q9NQH7,P17655,Q9NZ08,Q93009,Q16740,Q99538,Q99436,O75844,Q9UPT9
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
4,135,391,146,158,31,35,42,41,53,59,206,209,216,491,359,485,98,386,473,245,481,113,520,121,248,124
745,1135,391,209,1137,2137,248,206,2327,2966,885,3151,2222,59,3108,2760,473,146,41,3323,2659,1973,1019,4,53,1977,3201,3298,1631,98,1980,1554,1632,1888,31,2245,2254,216,3614,2355,2773,2361,2986,113,1652,135,1042,3085,2776,1322,2005,601,2989,675,158,3492,1921,3133,2378,481,3311,914,485,1188,730,1264,121,3177,520,2737,142...
0.4117022638315761,0.19067127264620573,0.7838890695289682,1.268129085929357,0.19067127264620573,-0.19560956934146895,1.118191455601226,1.2979715997804608,-0.2609563355332265,-0.5921770650124923,0.31734400267200297,-0.726880811724572,-0.22824695247054547,2.5402599154147643,-0.6930805097254553,-0.4587663248239629,0.66073...
3,643
Positive regulation of cytokine production
19
67
3.073878
0.002113
P30511,P14174,Q01650,P14373,Q9NY93,P05067,Q9BY67,Q7Z434,O75787,O75116,Q13049,P23396,Q8WXW3,P78536,P41440,Q9NRA0,Q9NUQ9,Q01082,O75955
Processes and pathways
GO Biological process
msigdb_gobp
138,15,143,395,429,29,304,420,296,293,188,437,468,216,90,227,102,365,249
1209,1210,1001,2502,1216,2794,293,296,249,1698,2757,2508,2863,590,29,1789,1081,653,2511,3256,1704,15,395,1878,2225,437,616,2928,138,2229,2764,1296,90,756,795,1557,216,2881,365,143,800,1815,1394,188,1092,2672,2267,1097,420,468,2178,1749,1834,978,1923,1674,3177,3053,919,304,522,2394,227,989,102,429,2308
0.15884550726049723,0.15884550726049723,0.25413257026133235,-0.3265940252928932,0.15884550726049723,-0.4920008457387619,0.9973494401983068,0.9973494401983068,1.118191455601226,-0.03347806686168351,-0.4587663248239629,-0.3265940252928932,-0.525313577596298,0.5366787829519797,3.6353042018995785,-0.06576592628969985,0.222...
3,643
Cell surface
30
95
3.070144
0.00214
Q4VCS5,P26038,Q8WTV0,Q9BQT9,P30511,P14174,Q01650,O75298,Q9H813,P00390,P05067,P11717,P10321,P02786,O75787,P42892,P00813,O75592,P51790,Q13641,P30533,O15484,P78536,P41440,P17655,Q9NWH9,Q99523,P25705,P15291,O75955
Localization
GO Cellular component
msigdb_gocc
512,501,8,275,138,15,143,393,150,25,29,154,532,409,296,53,56,186,459,329,457,209,216,90,473,371,114,237,112,249
1072,1073,1003,209,1137,393,531,186,296,249,3365,25,56,3617,1872,409,2508,590,29,3218,2141,3190,1012,3150,3191,1374,704,1457,2866,1081,532,3256,1704,887,1082,154,2656,15,2760,112,942,473,1084,843,237,501,2658,2066,3030,138,457,2229,90,53,2236,459,1888,2159,216,1308,143,1893,1310,1395,1727,2082,1894,1398,2596,2528,329,2...
0.2224334357534765,0.2224334357534765,0.25413257026133235,1.268129085929357,0.19067127264620573,0.7838890695289682,0.5988184783374502,1.387215394486587,0.9973494401983068,1.118191455601226,-0.9659039071751861,3.9014137223503935,2.6800374279695216,-2.342454069604444,-0.098122333905974,0.7531817696547146,-0.3265940252928...
3,643
transporter
15
66
3.065733
0.002171
Q9NR77,Q15012,P55735,P53985,O43772,Q9HD45,Q01650,Q9C0E2,Q567V2,P39210,O43681,Q8N1F7,P41440,Q9NUN5,Q99805
Functions
Panther Protein class
panther_protein_class
32,353,201,44,13,277,143,175,18,267,118,342,90,123,426
556,2917,2792,3511,2135,836,1283,118,13,648,1216,2795,2701,884,1972,2431,267,90,2934,2345,850,1386,1980,2073,44,1555,1982,201,798,2807,2163,143,2440,2268,353,417,18,1657,722,342,1498,861,3307,975,1331,2102,679,1837,2021,682,426,2292,3333,175,733,1350,1352,277,32,123,1763,3339,2308,2316,1604,693
0.5677772700633923,-0.5587053640309138,-0.4920008457387619,-1.2798752825252815,-0.19560956934146895,0.34885740302862467,0.12695555655645674,1.7982903969638317,5.243267115697605,0.47430803058067816,0.15884550726049723,-0.4920008457387619,-0.42560918711049844,0.31734400267200297,-0.13054795621506413,-0.29373844618932715,...
3,643
Receptor
12
33
3.065347
0.002174
Q9NR77,P11717,Q14108,P20645,Q8WTV0,O75787,A6NIH7,Q13641,Q567V2,P57105,P39210,Q9UQB8
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
32,154,255,37,8,296,46,329,18,238,267,26
46,2135,1695,2860,3483,296,2798,2328,3218,154,37,267,1976,238,540,329,255,3041,18,3045,3305,2822,8,1669,3056,1352,636,32,3377,360,3400,26,1443
3.0942250631129866,-0.19560956934146895,-0.03347806686168351,-0.525313577596298,-1.209424370050621,0.9973494401983068,-0.4920008457387619,-0.2609563355332265,-0.7947358122572576,1.5350292358486646,3.284999162596966,1.0578712931665288,-0.13054795621506413,1.1482768495977804,0.5988184783374502,0.9366227945511973,1.088056...
3,643
Abnormal peripheral nervous system physiology
12
55
3.036004
0.002397
Q9NR77,Q99720,P07602,Q7Z406,O95831,P02545,Q71SY5,P39210,O43681,Q9GZY8,P07196,Q00796
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,2,69,300,47,265,144,267,118,130,125,156
746,2212,118,1776,529,791,1456,47,265,125,69,1878,1222,310,1713,2711,267,2662,890,1467,1800,1155,2156,2238,2242,2349,3408,3471,156,3328,3490,2087,2091,627,1825,2946,144,464,300,859,2734,813,1675,1053,2,130,3533,2482,32,988,1064,3243,1521,1767,693
0.4117022638315761,-0.22824695247054547,1.7982903969638317,-0.06576592628969985,0.5988184783374502,0.3803099800917596,0.06298071889501843,3.0119856905575273,1.0578712931665288,1.7400910153055076,2.427791890653298,-0.098122333905974,0.15884550726049723,0.9670119136618348,-0.03347806686168351,-0.42560918711049844,1.05787...
3,643
Juvenile onset
16
46
3.024299
0.002492
P35579,Q9NR77,P16278,O15118,P22466,Q03252,P02545,P06753,Q14566,Q8NHS3,P39210,O75027,P54802,P07196,P41440,P06280
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
280,32,155,252,38,207,265,394,380,52,267,21,147,125,90,153
391,252,21,2652,265,2758,153,394,125,155,38,2064,707,280,3296,3578,267,1296,90,1467,618,2715,849,1155,2666,460,147,798,207,2358,1645,3473,1818,380,2533,3412,3393,52,1668,2612,2115,1936,2743,32,3245,1604
0.7838890695289682,1.08805639508316,4.373525061543824,-0.3925286203228279,1.0578712931665288,-0.4587663248239629,1.5350292358486646,0.7838890695289682,1.7400910153055076,1.5350292358486646,3.257840018273795,-0.16304347134508207,0.44303477605405855,1.027635769907882,-0.8629365633590367,-1.63783022894056,1.05787129316652...
3,643