term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5
values | subtype stringclasses 24
values | subtype_key stringclasses 24
values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tetrapyrrole metabolic process | 6 | 24 | 2.374259 | 0.017584 | P22830,Q9NUN5,P30519,O14678,O75027,Q7KZN9 | Processes and pathways | GO Biological process | msigdb_gobp | 0,123,14,176,21,286 | 932,176,21,3366,2142,653,0,14,3615,2342,1544,313,2157,3502,286,1337,820,1193,492,2844,123,2786,3243,3246 | 0.2857692407025649,1.446478167816503,4.373525061543824,-0.9659039071751861,-0.19560956934146895,0.47430803058067816,9.72862962082004,5.1928477731586264,-2.2291720974867153,-0.2609563355332265,0.030894617027511038,0.9670119136618348,-0.19560956934146895,-1.244601121096576,1.027635769907882,0.12695555655645674,0.38030998... | 3,643 |
Rho gtpase cycle | 42 | 172 | 2.367756 | 0.017896 | P78371,P84095,Q86VI3,P30519,Q96N67,P06753,Q13505,Q9Y5S2,Q9UQB8,Q92888,Q96JJ3,Q86UP2,P02786,Q07960,Q07065,Q14739,O75116,Q9BXS4,P67936,Q13813,P20700,P12814,Q9NZM3,O15173,Q96RU3,Q13464,O75976,P61201,Q96F07,Q7L576,P41440,P11274,Q14185,Q8NBN3,Q9Y6M7,P08670,Q01082,Q9BT78,O75955,Q96HY6,Q96DH6,Q9UEY8 | Processes and pathways | Reactome Pathways | msigdb_reactome | 378,139,140,14,401,394,19,162,26,424,302,301,409,298,173,416,293,50,181,315,310,308,336,199,204,328,206,461,344,340,90,338,94,225,361,104,365,385,249,384,517,526 | 645,3141,1774,199,2213,1136,789,1534,293,1368,3145,249,206,1372,1782,1786,409,3218,394,1789,1142,1457,104,2800,338,2707,308,3468,3552,3629,310,563,1622,14,1382,1542,1150,2876,1547,90,793,2344,709,1153,794,849,2156,1887,2583,2240,2349,1723,461,3489,1389,2250,1156,3120,181,378,3622,139,952,365,2257,800,2259,1310,173,298,... | 0.47430803058067816,-0.726880811724572,-0.06576592628969985,1.327766595224347,-0.22824695247054547,0.19067127264620573,0.3803099800917596,0.030894617027511038,0.9973494401983068,0.09500082791205905,-0.726880811724572,1.118191455601226,1.2979715997804608,0.09500082791205905,-0.06576592628969985,-0.06576592628969985,0.75... | 3,643 |
Apical part of cell | 17 | 70 | 2.364598 | 0.01805 | P11166,P55011,P26038,Q99538,P53985,O75787,Q01650,P51790,Q9Y4G8,O14523,P30825,O43865,P78536,O75955,P41440,P05067,Q9Y6M7 | Localization | GO Cellular component | msigdb_gocc | 279,440,501,520,44,296,143,459,81,453,54,55,216,249,90,29,361 | 1770,1207,453,1444,2793,2571,1003,1004,55,1367,296,249,3617,2508,1962,2054,3149,29,1374,704,2923,1457,279,3321,941,843,1015,2061,3422,1294,2517,501,54,2342,708,2068,1624,1544,2661,2151,90,459,44,3075,440,1723,2587,216,143,1029,715,2443,2086,1315,963,1243,1650,541,2460,1500,520,2737,2292,1354,2695,2912,1520,81,3315,361 | -0.06576592628969985,0.15884550726049723,0.6916031594494587,0.06298071889501843,-0.4920008457387619,-0.3595238272390506,0.25413257026133235,0.25413257026133235,2.6800374279695216,0.09500082791205905,0.9973494401983068,1.118191455601226,-2.342454069604444,-0.3265940252928932,-0.13054795621506413,-0.16304347134508207,-0.... | 3,643 |
Visual loss | 20 | 58 | 2.362538 | 0.01815 | O14773,O75503,A2RRP1,O60313,Q96JJ3,Q8NHS3,P00403,P03886,P07602,Q15046,P50897,O15078,P00846,P52732,P51798,P04439,Q15051,O75306,Q01082,Q9NWW5 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 391,24,528,529,302,52,559,62,69,566,72,194,74,326,460,590,223,471,365,251 | 528,2210,1281,1605,391,194,1956,529,471,2137,24,748,791,2705,559,3148,74,1872,62,2967,3450,590,69,1874,1792,1707,2338,2580,592,708,3296,1019,2232,3453,72,2238,460,326,948,2242,3471,365,658,897,1728,566,223,3393,52,3276,813,2286,302,3176,3178,251,2399,1064 | 0.5988184783374502,-0.22824695247054547,0.12695555655645674,-0.0012581004565036626,0.7838890695289682,1.3575144142492008,-0.13054795621506413,0.5988184783374502,0.6607309570482511,-0.19560956934146895,4.11230346222967,0.4117022638315761,0.3803099800917596,-0.42560918711049844,0.5677772700633923,-0.726880811724572,2.371... | 3,643 |
Abnormal pyramidal sign | 30 | 130 | 2.361903 | 0.018181 | Q99720,O75298,O75027,O14773,Q9NR77,P11166,O60313,Q8N0X7,O75787,O95831,O75251,Q9H6K4,Q969N2,Q6DKK2,P20700,O00754,P07602,Q15046,P00846,Q7LG56,Q9Y4W6,Q9H9S5,P41440,P04066,O75569,Q9NZ08,O75306,O43681,P07196,Q9UEY8 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,393,21,391,32,279,529,421,296,47,294,579,318,190,310,435,69,566,74,464,608,347,90,228,350,245,471,118,125,526 | 2321,646,1605,2408,1862,435,391,1210,3251,118,529,1865,2920,21,294,393,471,3144,350,296,3363,2417,791,47,74,1872,228,125,3151,69,1874,1963,2655,3256,279,1876,2424,591,2869,2925,1222,310,1796,2228,3028,2971,753,1462,1542,1971,754,2431,3033,2232,1975,90,1548,1467,2236,1718,3036,1887,1301,2520,2583,3626,1553,710,1387,2349... | -0.2609563355332265,0.47430803058067816,-0.0012581004565036626,-0.29373844618932715,-0.098122333905974,0.7224199472328477,0.7838890695289682,0.15884550726049723,-0.8287924672030076,1.7982903969638317,0.5988184783374502,-0.098122333905974,-0.5587053640309138,4.373525061543824,0.9973494401983068,0.7838890695289682,0.6607... | 3,643 |
Paresthesia | 6 | 30 | 2.357576 | 0.018395 | Q9NR77,Q9NZ08,P07196,P06280,P54802,P05067 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,245,125,153,147,29 | 1281,1956,791,1872,1288,29,3366,153,125,2142,279,1148,2658,2580,1548,2236,1553,2242,710,147,2349,1808,3204,464,2176,2622,579,32,245,2490 | 0.12695555655645674,-0.13054795621506413,0.3803099800917596,-0.098122333905974,0.12695555655645674,3.6353042018995785,-0.9659039071751861,1.5350292358486646,1.7400910153055076,-0.19560956934146895,1.027635769907882,0.19067127264620573,-0.3925286203228279,-0.3595238272390506,0.030894617027511038,-0.22824695247054547,0.0... | 3,643 |
metalloprotease | 8 | 27 | 2.356143 | 0.018466 | P22695,P52888,Q9UIQ6,Q9NZ08,P42892,Q9NQH7,O75844,P55786 | Functions | Panther Protein class | panther_protein_class | 311,98,42,245,53,386,248,31 | 1137,2137,248,885,409,3108,2760,311,3323,1713,53,98,1554,31,658,1042,2776,1322,1188,1264,2737,1422,386,3137,245,42,608 | 0.19067127264620573,-0.19560956934146895,1.118191455601226,0.31734400267200297,0.7531817696547146,-0.6930805097254553,-0.4587663248239629,0.9670119136618348,-0.8971691305719629,-0.03347806686168351,2.763483088965262,1.9718833674139287,0.030894617027511038,3.6085359292973544,0.47430803058067816,0.25413257026133235,-0.45... | 3,643 |
Dementia | 17 | 60 | 2.355257 | 0.01851 | P03886,P20700,O60313,Q14108,P07602,P27544,O15118,P61916,O96008,Q9Y487,P00846,Q7LG56,Q14203,O43681,Q9NWW5,Q96RR1,P05067 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 62,310,529,255,69,502,252,351,500,43,74,464,415,118,251,319,29 | 1605,252,118,529,1078,881,500,2705,559,74,62,2967,703,2758,2654,29,1013,69,1376,2655,2869,310,1796,944,2228,502,753,754,1624,2661,890,1301,2242,1387,2349,351,2721,955,1992,3473,255,415,665,1827,464,3393,2608,2012,3091,2624,1675,319,3177,2482,251,1064,1521,3519,1690,43 | -0.0012581004565036626,1.08805639508316,1.7982903969638317,0.5988184783374502,0.2224334357534765,0.31734400267200297,0.6298028841948623,-0.42560918711049844,0.5677772700633923,2.371337868662573,2.512197372488192,-0.5921770650124923,0.44303477605405855,-0.4587663248239629,-0.3925286203228279,3.6353042018995785,0.2541325... | 3,643 |
Cell activation | 34 | 149 | 2.355015 | 0.018522 | Q92538,P46379,P26038,Q9HCL2,P30511,P14174,Q9Y6D9,P05067,P35579,Q9UQ84,P22466,Q9BY67,P02786,P80404,Q96L92,P30825,P00813,Q92542,P24390,P23396,P12814,Q15046,Q8WXW3,P12956,P04439,O96028,P78536,Q9NPF0,P11274,Q9NRA0,P31749,Q9NUQ9,P51809,O95219 | Processes and pathways | GO Biological process | msigdb_gobp | 515,3,501,5,138,15,555,29,280,33,38,304,409,413,575,54,56,317,562,437,308,566,468,83,590,87,216,492,338,227,592,102,476,235 | 1207,1952,3065,2792,2323,2410,2501,2215,2860,1217,235,2702,3365,87,2757,3147,56,3617,409,703,2508,590,1288,29,1873,3218,1081,653,1144,1377,3256,1704,338,1082,3193,3591,308,83,3513,15,3629,1083,1084,1620,2337,38,437,562,1148,501,138,54,592,2874,708,2229,1018,280,3200,1151,1296,1547,1086,1548,3,3155,2582,3440,3344,476,13... | 0.15884550726049723,-0.13054795621506413,-0.6593637349435877,-0.4920008457387619,-0.2609563355332265,-0.29373844618932715,-0.3265940252928932,-0.22824695247054547,-0.525313577596298,0.15884550726049723,1.1482768495977804,-0.42560918711049844,-0.9659039071751861,2.11542427763213,-0.4587663248239629,-0.726880811724572,2.... | 3,643 |
Glycerophospholipid biosynthesis | 6 | 35 | 2.349121 | 0.018818 | Q8N2A8,Q9HCL2,Q8IV08,Q9NPH0,P35790,Q8NCC3 | Processes and pathways | Reactome Pathways | msigdb_reactome | 68,5,73,111,51,28 | 3510,584,2700,2221,2651,1147,51,2232,891,3557,2934,2880,1025,3165,905,2607,73,68,3394,28,1916,602,603,358,3179,3053,2838,984,1191,5,111,2482,1196,2400,185 | -1.2798752825252815,0.5366787829519797,-0.42560918711049844,-0.22824695247054547,-0.3925286203228279,0.19067127264620573,2.8742639930235563,-0.22824695247054547,0.31734400267200297,-1.4935285643358234,-0.5587053640309138,-0.525313577596298,0.25413257026133235,-0.726880811724572,0.31734400267200297,-0.3595238272390506,2... | 3,643 |
Heterogeneous | 17 | 46 | 2.345635 | 0.018995 | Q9NR77,P11717,P03886,Q9Y3D3,Q15555,O15344,Q15051,P61916,P00846,Q9NWH9,Q14203,P02545,P06753,P07196,O75844,P05067,P29372 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,154,62,198,355,253,223,351,74,371,415,265,394,125,248,29,438 | 253,531,248,2651,74,1872,265,62,2967,1288,29,394,125,154,2331,3552,2515,438,592,708,2229,2764,2232,2933,1155,1301,460,1632,2242,2716,351,1033,415,223,355,1566,2942,3226,2997,3630,3561,2783,32,371,198,693 | 1.08805639508316,0.5988184783374502,1.118191455601226,-0.3925286203228279,2.371337868662573,-0.098122333905974,1.0578712931665288,2.512197372488192,-0.5921770650124923,0.12695555655645674,3.6353042018995785,0.7838890695289682,1.7400910153055076,1.5350292358486646,-0.2609563355332265,-1.4576838354723742,-0.3265940252928... | 3,643 |
Regulation of production of molecular mediator of immune response | 12 | 31 | 2.344264 | 0.019065 | Q96FV9,P02786,Q7Z434,P30511,Q9NQT5,P14174,Q01650,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0 | Processes and pathways | GO Biological process | msigdb_gobp | 681,409,420,138,638,15,143,590,87,429,522,227 | 2502,87,409,590,2509,653,15,1878,138,2229,1548,143,1727,2526,1404,2535,969,1737,420,2178,1923,681,914,1928,3235,3479,522,638,2394,227,429 | -0.3265940252928932,2.11542427763213,0.7531817696547146,0.5366787829519797,-0.3265940252928932,0.47430803058067816,4.964849362308119,-0.098122333905974,1.623176179314646,-0.22824695247054547,0.030894617027511038,1.5938382520831849,-0.03347806686168351,-0.3265940252928932,0.09500082791205905,-0.3265940252928932,0.285769... | 3,643 |
Pdz domain binding | 6 | 17 | 2.342349 | 0.019163 | Q9BY67,P51790,Q9Y4G8,Q9UBI6,P78536,Q9UQB8 | Functions | GO Molecular function | msigdb_gomf | 304,459,81,451,216,26 | 2793,1015,2517,1628,459,2162,216,964,1166,572,2614,304,451,1360,26,81,1951 | -0.4920008457387619,0.25413257026133235,-0.3265940252928932,-0.0012581004565036626,0.6916031594494587,-0.19560956934146895,1.2382387072449188,0.2857692407025649,0.19067127264620573,0.5677772700633923,-0.3595238272390506,0.9973494401983068,0.7224199472328477,0.12695555655645674,3.9014137223503935,2.2579809707838456,-0.0... | 3,643 |
Ventricular arrhythmia | 13 | 42 | 2.341649 | 0.019199 | P03886,P49748,P23786,P00846,O43772,Q7LG56,P02545,P10253,P42892,P09493,Q96RR1,Q8NFF5,P50336 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 62,412,200,74,13,464,265,266,53,215,319,382,313 | 13,471,1454,2705,559,74,265,62,2967,1289,2142,215,3572,266,2331,2332,3468,3552,843,1796,200,1544,3115,1546,53,2432,412,313,849,2242,2256,2259,959,1033,464,382,976,3331,2180,319,1581,2399 | 5.243267115697605,0.6607309570482511,0.06298071889501843,-0.42560918711049844,0.5677772700633923,2.371337868662573,1.0578712931665288,2.512197372488192,-0.5921770650124923,0.12695555655645674,-0.19560956934146895,1.2382387072449188,-1.6016175956969314,1.0578712931665288,-0.2609563355332265,-0.2609563355332265,-1.174345... | 3,643 |
Lymphocyte activation | 26 | 110 | 2.336534 | 0.019463 | P46379,P26038,Q9HCL2,P30511,P14174,Q9Y6D9,P35579,Q9UQ84,P22466,Q9BY67,P02786,Q96L92,P30825,P00813,Q92542,P24390,P23396,Q8WXW3,P12956,P04439,O96028,P78536,Q9NPF0,P31749,Q9NUQ9,P51809 | Processes and pathways | GO Biological process | msigdb_gobp | 3,501,5,138,15,555,280,33,38,304,409,575,54,56,317,562,437,468,83,590,87,216,492,592,102,476 | 1952,2792,2410,2215,2860,1217,2702,3365,87,2757,3147,56,409,703,2508,590,1288,1873,3218,1081,1144,1377,3256,1082,3193,83,3513,15,3629,1083,1084,38,437,562,1148,501,138,54,592,2874,708,2229,1018,280,3200,1151,1296,1547,1086,1548,3,3440,3344,476,1553,1889,1233,2436,2162,1559,1390,216,3038,1988,2080,2720,1893,2938,1815,32... | -0.13054795621506413,-0.4920008457387619,-0.29373844618932715,-0.22824695247054547,-0.525313577596298,0.15884550726049723,-0.42560918711049844,-0.9659039071751861,2.11542427763213,-0.4587663248239629,-0.726880811724572,2.6800374279695216,0.7531817696547146,0.44303477605405855,-0.3265940252928932,0.5366787829519797,0.12... | 3,643 |
Cellular monovalent inorganic cation homeostasis | 9 | 28 | 2.331018 | 0.019752 | P55011,P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7 | Processes and pathways | GO Biological process | msigdb_gobp | 440,72,405,43,296,82,251,24,361 | 24,296,1962,2054,3149,2141,1144,3322,3197,72,2156,459,3075,440,2587,1036,965,1914,1331,82,2180,405,251,1274,2401,43,3315,361 | 4.11230346222967,0.9973494401983068,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,-0.19560956934146895,0.19067127264620573,-0.8971691305719629,-0.7607655898218467,2.399583395405736,-0.19560956934146895,0.6916031594494587,-0.6593637349435877,0.7224199472328477,-0.3595238272390506,0.25413257026133235,0.285... | 3,643 |
Positive regulation of intracellular signal transduction | 30 | 160 | 2.329871 | 0.019813 | O15344,Q86VI3,P14174,P14373,O00291,Q9NY93,Q9UMX5,P05067,P19474,Q8WVQ1,P02786,Q7Z434,O75116,P00813,P32929,Q13049,Q14457,P29372,P55735,Q13464,O43707,O60858,Q9Y4G8,Q13641,Q9NRA0,Q15555,O75569,Q9NWH9,O60826,P23246 | Processes and pathways | GO Biological process | msigdb_gobp | 253,140,15,395,390,429,27,29,36,423,409,420,293,56,187,188,189,438,201,328,325,80,81,329,227,355,350,371,247,375 | 1770,390,1605,2322,1209,1444,2793,1606,2050,1001,253,2501,2502,933,557,325,1138,1076,247,80,1614,293,2796,350,3068,1616,1783,56,409,2863,1288,1289,29,3218,1012,1789,1457,1081,653,2511,654,15,395,3629,1459,1794,3258,843,36,2225,2337,375,437,1223,3322,2658,438,1540,2066,2928,2874,3520,187,708,2229,2431,1547,3117,709,1887... | -0.06576592628969985,0.7838890695289682,-0.0012581004565036626,-0.2609563355332265,0.15884550726049723,0.06298071889501843,-0.4920008457387619,-0.0012581004565036626,-0.16304347134508207,0.25413257026133235,1.08805639508316,-0.3265940252928932,-0.3265940252928932,0.2857692407025649,0.5677772700633923,0.9366227945511973... | 3,643 |
Mitochondrial transmembrane transport | 13 | 57 | 2.327254 | 0.019952 | Q9BSK2,O95563,P21796,Q9NWR8,P23786,P00846,Q9H4I9,O43772,O95831,P25705,O75027,O75964,Q8IYU8 | Processes and pathways | GO Biological process | msigdb_gobp | 260,152,34,305,200,74,244,13,47,237,21,214,257 | 1954,1283,13,2795,21,2137,1450,1218,214,1698,1372,152,47,500,74,1873,2141,3256,2331,1145,3544,34,200,3112,237,1226,3487,3264,2073,711,2522,2812,1649,2000,719,257,2949,2734,2468,3634,2906,682,320,3505,577,260,733,244,1057,3058,822,2485,305,924,2308,608,693 | -0.13054795621506413,0.12695555655645674,5.243267115697605,-0.4920008457387619,4.373525061543824,-0.19560956934146895,0.06298071889501843,0.15884550726049723,1.2382387072449188,-0.03347806686168351,0.09500082791205905,1.5350292358486646,3.0119856905575273,0.6298028841948623,2.371337868662573,-0.098122333905974,-0.19560... | 3,643 |
Nuclear inner membrane | 6 | 24 | 2.325075 | 0.020068 | P20700,Q99720,Q9UH99,Q03252,Q14739,O75844 | Localization | GO Cellular component | msigdb_gocc | 310,2,170,207,416,248 | 248,2326,3102,310,1882,890,849,3161,2250,207,1237,624,416,3043,442,2780,1829,1664,1923,2,1581,1680,170,744 | 1.118191455601226,-0.2609563355332265,-0.6930805097254553,0.9670119136618348,-0.098122333905974,0.31734400267200297,0.34885740302862467,-0.726880811724572,-0.22824695247054547,1.2979715997804608,0.15884550726049723,0.5055225334229401,0.7531817696547146,-0.6257295573052645,0.7224199472328477,-0.4587663248239629,-0.06576... | 3,643 |
Kinetic tremor | 12 | 35 | 2.323103 | 0.020174 | P20700,Q14108,P07602,Q15233,Q9Y4W6,Q01082,Q9Y448,O75027,O43681,Q9BUB7,Q9NQH7,P41440 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 310,255,69,567,608,365,348,21,118,447,386,90 | 1862,1210,2571,118,21,2758,69,1874,2925,1222,310,1293,3028,592,1971,90,2877,1885,1088,365,955,255,567,2452,3393,859,1664,2622,447,386,1064,1521,3286,348,608 | -0.098122333905974,0.15884550726049723,-0.3595238272390506,1.7982903969638317,4.373525061543824,-0.4587663248239629,2.427791890653298,-0.098122333905974,-0.5587053640309138,0.15884550726049723,0.9670119136618348,0.12695555655645674,-0.6257295573052645,0.5366787829519797,-0.13054795621506413,2.058127752852981,-0.5253135... | 3,643 |
Babinski sign | 17 | 91 | 2.320004 | 0.020341 | Q9NR77,P11166,Q99720,P20700,P07602,Q8N0X7,P00846,Q969N2,O75787,O95831,O75298,O75027,O43681,O14773,P41440,P07196,Q6DKK2 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,279,2,310,69,421,74,318,296,47,393,21,118,391,90,125,190 | 2321,646,2408,1862,435,391,1210,118,529,1865,2920,21,393,3144,296,2417,791,47,74,125,3151,69,1963,2655,3256,279,1876,2424,310,1796,2228,2971,753,1462,1542,1971,754,2431,3033,2232,1975,90,1467,3036,1301,2520,3626,1387,2349,2880,797,3471,801,1992,1238,963,964,3502,668,2452,190,2729,1407,2895,3393,421,859,2098,1918,2012,8... | -0.2609563355332265,0.47430803058067816,-0.29373844618932715,-0.098122333905974,0.7224199472328477,0.7838890695289682,0.15884550726049723,1.7982903969638317,0.5988184783374502,-0.098122333905974,-0.5587053640309138,4.373525061543824,0.7838890695289682,-0.726880811724572,0.9973494401983068,-0.29373844618932715,0.3803099... | 3,643 |
Abnormality of the ribs | 19 | 71 | 2.318804 | 0.020406 | Q7RTS9,P02545,P54802,Q9UBM7,P16278,Q9UHX1,Q96L58,P15586,O75718,Q14739,O95831,P00813,O00754,O95155,O75431,O96028,Q96HY6,O60826,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 11,265,147,289,155,171,303,410,295,416,47,56,435,307,213,87,384,247,248 | 435,3610,1210,2502,247,1005,2412,499,213,3216,295,248,3288,307,1372,47,87,56,265,3150,410,155,2145,1707,2061,2337,2927,2516,707,3297,3557,1886,1155,460,147,2434,2257,1989,1815,3270,801,1562,416,2887,1566,2889,1038,2728,2364,569,1172,3475,2003,11,1500,974,2610,2612,2183,384,303,2736,3001,2478,1852,289,171,2959,3012,1069... | 0.7224199472328477,-2.1540615170130093,0.15884550726049723,-0.3265940252928932,1.118191455601226,0.25413257026133235,-0.29373844618932715,0.6298028841948623,1.2382387072449188,-0.7947358122572576,0.9973494401983068,1.118191455601226,-0.8629365633590367,0.9670119136618348,0.09500082791205905,3.0119856905575273,2.1154242... | 3,643 |
Limb girdle muscle weakness | 10 | 28 | 2.317788 | 0.020461 | P07602,Q8TD16,Q7LG56,Q14331,P02545,P06753,Q9H9S5,Q13126,Q96RR1,Q13049 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 69,272,464,477,265,394,347,20,319,188 | 2210,1000,529,2136,3404,265,394,69,2331,890,2432,2073,2242,2349,2358,188,20,2529,477,1165,464,272,319,347,1064,2960,1604,1068 | -0.22824695247054547,0.25413257026133235,0.5988184783374502,-0.19560956934146895,-1.0350054838275398,1.0578712931665288,0.7838890695289682,2.427791890653298,-0.2609563355332265,0.31734400267200297,-0.29373844618932715,-0.16304347134508207,-0.22824695247054547,-0.2609563355332265,-0.2609563355332265,1.387215394486587,4.... | 3,643 |
Protease binding | 7 | 33 | 2.304159 | 0.021214 | P46379,P07602,O75251,P14174,P25705,O75955,P41440 | Functions | GO Molecular function | msigdb_gomf | 3,69,294,15,237,249,90 | 294,249,3617,2758,1288,3218,1012,3191,69,15,237,3424,2343,90,3,1801,2242,2349,952,1093,3082,1096,2890,1652,3045,2989,1674,319,3177,3056,1064,1593,1437 | 0.9973494401983068,1.118191455601226,-2.342454069604444,-0.4587663248239629,0.12695555655645674,-0.7947358122572576,0.25413257026133235,-0.7607655898218467,2.427791890653298,4.964849362308119,1.1482768495977804,-1.069696640684267,-0.2609563355332265,2.058127752852981,7.00443820279511,-0.06576592628969985,-0.22824695247... | 3,643 |
Hydrolase activity acting on glycosyl bonds | 13 | 31 | 2.304071 | 0.021219 | P16278,P23396,O00754,P04066,Q9BTY2,O60476,P08236,P10253,O60502,P54802,O75503,P06280,P29372 | Functions | GO Molecular function | msigdb_gomf | 155,437,435,228,115,264,455,266,84,147,24,153,438 | 435,1282,264,84,24,703,228,153,1013,3538,455,266,2512,3513,155,2869,437,3073,438,1383,1623,147,1892,3490,1997,3205,478,2455,2988,115,1757 | 0.7224199472328477,0.12695555655645674,1.0578712931665288,2.144013371443563,4.11230346222967,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,-1.3862754857551036,0.6916031594494587,1.0578712931665288,-0.3265940252928932,-1.2798752825252815,1.5350292358486646,-0.525313577596298,0.72241994723... | 3,643 |
Membrane protein proteolysis | 9 | 14 | 2.304063 | 0.021219 | P35579,Q9Y5X1,Q9NZ08,Q13464,Q16740,P78536,Q92542,Q9H300,Q8TCT8 | Processes and pathways | GO Biological process | msigdb_gobp | 280,107,245,328,113,216,317,491,158 | 1137,280,1150,216,328,113,158,3492,317,491,245,1854,608,107 | 0.19067127264620573,1.027635769907882,0.19067127264620573,1.2382387072449188,0.9366227945511973,1.8563207862044178,1.5350292358486646,-1.209424370050621,0.9670119136618348,0.6607309570482511,1.1482768495977804,-0.06576592628969985,0.5366787829519797,1.943054324684516 | 3,643 |
Transforming growth factor beta receptor signaling pathway | 6 | 31 | 2.30063 | 0.021413 | Q8WUH2,Q06481,Q92896,Q8N3R9,Q13573,P78536 | Processes and pathways | GO Biological process | msigdb_gobp | 133,39,136,148,88,216 | 2322,2049,2502,1288,3218,1457,1791,3520,1296,229,1155,2436,216,39,2671,88,2270,2271,1909,148,133,136,2378,1049,1923,2562,1855,3138,744,2406,1132 | -0.2609563355332265,-0.16304347134508207,-0.3265940252928932,0.12695555655645674,-0.7947358122572576,0.06298071889501843,-0.06576592628969985,-1.315246174406957,0.12695555655645674,1.1783129469800828,0.19067127264620573,-0.29373844618932715,1.2382387072449188,3.257840018273795,-0.3925286203228279,2.11542427763213,-0.22... | 3,643 |
Trans golgi network vesicle budding | 12 | 42 | 2.296565 | 0.021644 | P11717,P20645,P51809,P02786,Q9Y5X1,P15586,O43493,O75976,Q99523,O14976,Q9H3P7,P05067 | Processes and pathways | Reactome Pathways | msigdb_reactome | 154,37,476,409,107,410,142,206,114,392,523,29 | 2321,1952,834,1774,392,142,2963,2860,588,1367,206,409,29,1702,1703,2144,154,410,37,1155,1300,476,1556,1889,2768,3571,952,2257,1160,1727,2596,2088,3600,1663,3355,515,2014,114,1933,523,107,2407 | -0.2609563355332265,-0.13054795621506413,0.34885740302862467,-0.06576592628969985,0.7838890695289682,1.5938382520831849,-0.5921770650124923,-0.525313577596298,0.5366787829519797,0.09500082791205905,1.2979715997804608,0.7531817696547146,3.6353042018995785,-0.03347806686168351,-0.03347806686168351,-0.19560956934146895,1.... | 3,643 |
Protein processing | 18 | 51 | 2.284054 | 0.022368 | P35579,Q9Y366,Q92896,P17655,O75787,Q15392,O75976,Q96F07,Q9BXS4,Q9H9S5,P42892,O75503,Q9NQH7,O75844,Q92542,Q9H300,Q969M3,P78536 | Processes and pathways | GO Biological process | msigdb_gobp | 280,290,136,473,296,45,206,344,50,347,53,24,386,248,317,491,356,216 | 3101,2137,24,296,248,206,2799,3148,3190,3191,1791,3406,473,3470,280,53,3298,2244,2245,2254,216,658,1561,2986,45,3501,1652,1042,3085,2989,1500,3492,317,136,356,344,2833,1264,520,2737,3179,50,491,347,2842,386,2400,2308,3285,290,608 | -0.6930805097254553,-0.19560956934146895,4.11230346222967,0.9973494401983068,1.118191455601226,1.2979715997804608,-0.4920008457387619,-0.726880811724572,-0.7607655898218467,-0.7607655898218467,-0.06576592628969985,-1.0350054838275398,0.6607309570482511,-1.174345720866778,1.027635769907882,2.763483088965262,-0.862936563... | 3,643 |
Monovalent inorganic cation homeostasis | 9 | 32 | 2.282382 | 0.022467 | P55011,P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7 | Processes and pathways | GO Biological process | msigdb_gobp | 440,72,405,43,296,82,251,24,361 | 24,296,1289,1962,2054,3149,2141,1144,3322,3197,72,2156,459,3075,440,2587,1036,965,1914,1331,82,2612,2180,405,251,1274,2401,43,2407,694,3315,361 | 4.11230346222967,0.9973494401983068,0.12695555655645674,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,-0.19560956934146895,0.19067127264620573,-0.8971691305719629,-0.7607655898218467,2.399583395405736,-0.19560956934146895,0.6916031594494587,-0.6593637349435877,0.7224199472328477,-0.3595238272390506,0.254... | 3,643 |
Muscle stiffness | 8 | 22 | 2.28203 | 0.022488 | P11166,P07602,P23786,P00846,P53985,Q15392,P52732,P06753 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 279,69,200,74,44,45,326,394 | 3363,2652,74,394,69,279,200,1717,412,326,44,2242,797,45,2729,1915,2011,2112,3535,1064,3519,1692 | -0.9659039071751861,-0.3925286203228279,2.371337868662573,0.7838890695289682,2.427791890653298,1.027635769907882,1.327766595224347,-0.03347806686168351,0.7531817696547146,0.9366227945511973,3.1215736355280526,-0.22824695247054547,0.3803099800917596,3.1215736355280526,-0.42560918711049844,-0.098122333905974,-0.130547956... | 3,643 |
External side of plasma membrane | 12 | 27 | 2.281682 | 0.022508 | P02786,P17655,P30511,O75787,Q01650,P51790,P15291,P42892,O75955,P00813,P00390,P41440 | Localization | GO Cellular component | msigdb_gocc | 409,473,138,296,143,459,112,53,249,56,25,90 | 1003,296,249,3365,25,56,3617,409,2508,3218,1012,3150,1374,1082,2760,112,942,473,2658,138,90,53,2236,459,143,1031,512 | 0.25413257026133235,0.9973494401983068,1.118191455601226,-0.9659039071751861,3.9014137223503935,2.6800374279695216,-2.342454069604444,0.7531817696547146,-0.3265940252928932,-0.7947358122572576,0.25413257026133235,-0.726880811724572,0.09500082791205905,0.2224334357534765,-0.4587663248239629,1.8563207862044178,0.28576924... | 3,643 |
Regulation of synapse structure or activity | 10 | 34 | 2.281464 | 0.022521 | Q14012,P50897,Q9BQT9,Q14203,Q13641,Q15375,Q12834,Q7L576,Q9UQB8,P05067 | Processes and pathways | GO Biological process | msigdb_gobp | 379,72,275,415,329,418,284,340,26,29 | 932,29,1701,2144,3221,843,3111,2974,72,2349,1723,1023,3077,2437,3079,2721,284,329,379,415,1564,418,1097,1567,340,1186,2624,275,1056,522,3063,1853,743,26 | 0.2857692407025649,3.6353042018995785,-0.03347806686168351,-0.19560956934146895,-0.7947358122572576,0.34885740302862467,-0.6930805097254553,-0.5921770650124923,2.399583395405736,-0.2609563355332265,-0.03347806686168351,0.25413257026133235,-0.6593637349435877,-0.29373844618932715,-0.6593637349435877,-0.42560918711049844... | 3,643 |
Response to transforming growth factor beta | 8 | 39 | 2.278291 | 0.022709 | Q8WUH2,P49354,Q06481,Q92896,O75116,Q8N3R9,Q13573,P78536 | Processes and pathways | GO Biological process | msigdb_gobp | 133,229,39,136,293,148,88,216 | 2322,2134,2049,2502,293,1288,3218,1457,1791,3520,1296,2712,3117,229,1155,2436,216,39,1479,328,2671,88,2270,2271,1909,148,133,1749,136,2378,1049,1923,1192,2562,1855,3138,744,2406,1132 | -0.2609563355332265,-0.19560956934146895,-0.16304347134508207,-0.3265940252928932,0.9973494401983068,0.12695555655645674,-0.7947358122572576,0.06298071889501843,-0.06576592628969985,-1.315246174406957,0.12695555655645674,-0.42560918711049844,-0.6930805097254553,1.1783129469800828,0.19067127264620573,-0.2937384461893271... | 3,643 |
Lipid localization | 16 | 94 | 2.276458 | 0.022819 | Q9H4L5,Q99720,Q14108,P11166,P07602,P22466,O15118,Q8WTV0,P23786,P61916,Q16739,O15260,O43772,P14174,O14678,P35790 | Processes and pathways | GO Biological process | msigdb_gobp | 100,2,255,279,69,38,252,8,200,351,330,108,13,15,176,51 | 1206,3527,453,176,252,108,1003,13,2754,1214,1369,1455,1286,2221,2651,2653,3617,1787,703,2508,1012,3191,69,3538,1874,1374,1704,279,15,2869,1797,1293,38,200,1622,3615,592,364,1224,2342,1225,51,2934,3264,351,2881,2163,1392,2938,1815,255,2673,3301,330,3042,3371,2001,3456,810,3593,2900,8,1336,1923,574,1263,2,3630,2688,3553,... | 0.15884550726049723,-1.3507131280591325,0.6916031594494587,1.446478167816503,1.08805639508316,1.914184390727662,0.25413257026133235,5.243267115697605,-0.4587663248239629,0.15884550726049723,0.09500082791205905,0.06298071889501843,0.12695555655645674,-0.22824695247054547,-0.3925286203228279,-0.3925286203228279,-2.342454... | 3,643 |
Abnormal biliary tract morphology | 6 | 26 | 2.273669 | 0.022986 | Q14108,P07602,O15078,P14174,O43681,Q9NUN5 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 255,69,194,15,118,123 | 194,118,265,703,69,653,15,3437,1973,3155,1802,2238,2242,658,803,255,416,1491,2378,2621,2483,123,1064,1202,2789,1604 | 1.3575144142492008,1.7982903969638317,1.0578712931665288,0.44303477605405855,2.427791890653298,0.47430803058067816,4.964849362308119,-1.104482929673742,-0.13054795621506413,-0.726880811724572,-0.06576592628969985,-0.22824695247054547,-0.22824695247054547,0.47430803058067816,0.3803099800917596,1.08805639508316,0.7531817... | 3,643 |
Membrane protein ectodomain proteolysis | 6 | 11 | 2.271692 | 0.023105 | P35579,Q9Y5X1,Q9NZ08,P78536,Q92542,Q8TCT8 | Processes and pathways | GO Biological process | msigdb_gobp | 280,107,245,216,317,158 | 1137,280,1150,216,328,158,3492,317,245,1854,107 | 0.19067127264620573,1.027635769907882,0.19067127264620573,1.2382387072449188,0.9366227945511973,1.5350292358486646,-1.209424370050621,0.9670119136618348,1.1482768495977804,-0.06576592628969985,1.943054324684516 | 3,643 |
Abnormal circulating lipid concentration | 21 | 79 | 2.268174 | 0.023319 | P22830,O43772,P02545,Q9UBM7,P06280,P49748,P28070,Q15392,Q14739,Q969N2,P07602,Q15056,P23786,Q03252,O43707,O75431,P61916,P31751,O75844,Q9NUN5,Q9UIG0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,13,265,289,153,412,164,45,416,318,69,462,200,207,325,213,351,364,248,123,527 | 1210,325,1610,13,3483,213,2647,248,1451,1285,701,3617,265,153,1011,69,2143,3623,2333,0,200,164,888,364,3514,3199,1623,3343,2150,3578,1464,2232,1467,794,412,849,3264,1802,3386,2238,2716,2880,798,351,1089,2257,207,1159,507,3328,959,416,462,45,1566,3168,2532,965,2942,1170,1914,3132,3517,976,813,318,1581,3001,3280,123,1197... | 0.15884550726049723,0.9366227945511973,-0.0012581004565036626,5.243267115697605,-1.209424370050621,1.2382387072449188,-0.3925286203228279,1.118191455601226,0.06298071889501843,0.12695555655645674,0.44303477605405855,-2.342454069604444,1.0578712931665288,1.5350292358486646,0.25413257026133235,2.427791890653298,-0.195609... | 3,643 |
Adaptive immune response | 15 | 49 | 2.261684 | 0.023717 | Q9UQ84,Q9NUQ9,P10321,Q9BY67,P02786,Q9NZ08,P30511,Q9NQT5,O15400,P14373,P04439,P00813,Q9BX67,O96028,P78536 | Processes and pathways | GO Biological process | msigdb_gobp | 33,102,532,304,409,245,138,638,586,395,590,56,488,87,216 | 586,2502,1217,87,3147,56,1872,409,2508,590,1081,532,3256,1704,3513,395,138,2229,1385,1296,1547,1086,1548,1553,1632,216,3038,1028,2938,1310,2526,1031,1404,2535,969,2776,1737,1923,681,3311,914,1928,488,304,638,102,245,3063,33 | 0.5366787829519797,-0.3265940252928932,0.15884550726049723,2.11542427763213,-0.726880811724572,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.2224334357534765,0.5988184783374502,-0.8287924672030076,-0.03347806686168351,-1.2798752825252815,0.7838890695289682,1.623176179... | 3,643 |
Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 11 | 37 | 2.258773 | 0.023898 | Q9UQ84,Q9NUQ9,Q9BY67,P02786,P30511,Q9NQT5,P04439,P00813,O15400,O96028,P78536 | Processes and pathways | GO Biological process | msigdb_gobp | 33,102,304,409,138,638,590,56,586,87,216 | 586,2502,1217,87,3147,56,1872,409,2508,590,1081,3256,1704,3513,138,2229,1385,1296,1086,1548,1553,1632,216,2938,1310,2526,1404,2535,969,1737,681,914,1928,304,638,102,33 | 0.5366787829519797,-0.3265940252928932,0.15884550726049723,2.11542427763213,-0.726880811724572,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.2224334357534765,-0.8287924672030076,-0.03347806686168351,-1.2798752825252815,1.623176179314646,-0.22824695247054547,0.09500082... | 3,643 |
Myotube differentiation | 6 | 17 | 2.258585 | 0.023909 | P35579,Q8IV08,Q96TA1,Q99523,O75955,P41440 | Processes and pathways | GO Biological process | msigdb_gobp | 280,73,333,114,249,90 | 249,3218,473,280,90,1086,3270,1816,1165,1097,73,333,114,1422,1937,2031,2036 | 1.118191455601226,-0.7947358122572576,0.6607309570482511,1.027635769907882,2.058127752852981,0.2224334357534765,-0.8287924672030076,-0.06576592628969985,0.19067127264620573,0.2224334357534765,2.399583395405736,0.9366227945511973,1.8563207862044178,0.09500082791205905,-0.098122333905974,-0.13054795621506413,-0.130547956... | 3,643 |
Protein homooligomerization | 6 | 48 | 2.250674 | 0.024406 | Q99720,Q06481,O94788,Q4G0X4,P14174,P32929 | Processes and pathways | GO Biological process | msigdb_gobp | 2,39,9,91,15,187 | 3527,2963,9,3364,1372,3147,2922,3291,2576,15,187,1970,1542,754,1150,3439,2158,2982,39,3166,414,2526,3606,211,1732,662,91,3391,1825,3305,1255,2734,1669,2382,2624,3178,2,2737,2738,320,447,549,490,1937,2199,3519,926,1692 | -1.3507131280591325,-0.5921770650124923,5.816916168706705,-0.9659039071751861,0.09500082791205905,-0.726880811724572,-0.5587053640309138,-0.8629365633590367,-0.3595238272390506,4.964849362308119,1.387215394486587,-0.13054795621506413,0.030894617027511038,0.4117022638315761,0.19067127264620573,-1.104482929673742,-0.1956... | 3,643 |
Rhoa gtpase cycle | 14 | 52 | 2.249598 | 0.024474 | P41440,O15173,P02786,Q86VI3,Q86UP2,Q07960,Q13464,P30519,O75116,O75955,Q96HY6,Q92888,P11274,Q8NBN3 | Processes and pathways | Reactome Pathways | msigdb_reactome | 90,199,409,140,301,298,328,14,293,249,384,424,338,225 | 645,199,2213,789,1534,293,249,1782,409,338,3468,563,1622,14,90,793,2344,709,794,1887,2240,3120,1310,298,3444,1643,2940,3121,328,3225,1315,416,965,1404,855,301,140,225,974,1330,424,1834,1835,384,863,1424,2389,3568,2556,988,3007,2037 | 0.47430803058067816,1.327766595224347,-0.22824695247054547,0.3803099800917596,0.030894617027511038,0.9973494401983068,1.118191455601226,-0.06576592628969985,0.7531817696547146,0.9061816816409076,-1.174345720866778,0.5677772700633923,-0.0012581004565036626,5.1928477731586264,2.058127752852981,0.3803099800917596,-0.26095... | 3,643 |
Carbohydrate derivative transport | 6 | 23 | 2.248307 | 0.024557 | Q86VD7,P07602,P61916,Q8WTV0,Q9HC21,P41440 | Processes and pathways | GO Biological process | msigdb_gobp | 256,69,351,8,553,90 | 2751,646,1003,2754,1873,69,2331,1145,90,351,1395,2274,2366,256,1177,573,2829,8,1336,2292,553,1432,1064 | -0.4587663248239629,0.47430803058067816,0.25413257026133235,-0.4587663248239629,-0.098122333905974,2.427791890653298,-0.2609563355332265,0.19067127264620573,2.058127752852981,0.8756881681175116,0.09500082791205905,-0.22824695247054547,-0.2609563355332265,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.492000... | 3,643 |
Joint contracture of the hand | 13 | 57 | 2.247507 | 0.024608 | Q9NR77,O95155,Q8WVQ1,Q8IZA0,Q15392,P02545,Q71SY5,P06753,P42892,O75530,O75844,P11274,P07196 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,307,423,141,45,265,144,394,53,86,248,338,125 | 1210,2919,2502,2794,499,86,248,307,265,394,125,338,2145,2925,2337,2927,844,3197,2711,1546,53,3117,1802,2667,798,2257,3328,1646,959,899,3389,765,45,1038,1172,3304,2893,144,141,1668,423,2541,2017,728,2736,2021,447,2193,869,32,1853,2041,2854,2565,1279,1767,693 | 0.15884550726049723,-0.5587053640309138,-0.3265940252928932,-0.4920008457387619,0.6298028841948623,2.11542427763213,1.118191455601226,0.9670119136618348,1.0578712931665288,0.7838890695289682,1.7400910153055076,0.9061816816409076,-0.19560956934146895,-0.5587053640309138,-0.2609563355332265,-0.5587053640309138,0.34885740... | 3,643 |
Positive regulation of adaptive immune response | 7 | 18 | 2.246703 | 0.024659 | Q9NUQ9,P02786,P30511,P04439,P00813,O15400,O96028 | Processes and pathways | GO Biological process | msigdb_gobp | 102,409,138,590,56,586,87 | 586,2502,87,56,1872,409,590,3256,138,1548,2526,2535,969,1923,914,1928,638,102 | 0.5366787829519797,-0.3265940252928932,2.11542427763213,2.6800374279695216,-0.098122333905974,0.7531817696547146,0.5366787829519797,-0.8287924672030076,1.623176179314646,0.030894617027511038,-0.3265940252928932,-0.3265940252928932,0.2857692407025649,-0.098122333905974,0.31734400267200297,-0.098122333905974,0.5055225334... | 3,643 |
Tight junction | 13 | 40 | 2.244058 | 0.024829 | P35579,P12814,P35580,P35221,Q7Z406,O43707,Q92797,P31751,Q8N3R9,Q9BX67,Q13813,Q16625,O14936 | Processes and pathways | KEGG Pathways | msigdb_kegg | 280,308,222,534,300,325,149,364,148,488,315,541,436 | 436,1074,325,1613,1289,2057,3023,841,308,1147,1968,2429,592,364,534,708,280,222,2347,1633,1723,1636,1637,1025,3165,2938,1029,315,1402,1166,541,300,148,149,2614,488,1199,2037,2404,1951 | 0.7224199472328477,0.2224334357534765,0.9366227945511973,-0.0012581004565036626,0.12695555655645674,-0.16304347134508207,-0.6257295573052645,0.34885740302862467,0.9670119136618348,0.19067127264620573,-0.13054795621506413,-0.29373844618932715,0.5366787829519797,0.845141841466991,0.5988184783374502,0.44303477605405855,1.... | 3,643 |
Transmembrane transport | 67 | 254 | 2.241705 | 0.02498 | Q9BSK2,Q86VD7,Q8WTV0,O96008,Q07820,Q6NT16,Q15629,O43772,Q8IXU6,Q01650,Q96H78,Q7L0J3,Q9HC07,O75298,Q99442,O75027,P39210,Q9HC21,Q7KZN9,P05067,Q16625,P46939,Q9UHG3,P11166,P21796,Q8N4V1,O95563,Q70HW3,P22466,Q06481,Q9NWR8,Q9UBX3,Q9BQT8,P53985,Q8TB61,O95831,Q96GC9,P16615,O14678,O75251,Q8NHS3,Q9HD20,P30825,O43865,Q6P4Q7,Q9BPX... | Processes and pathways | GO Biological process | msigdb_gobp | 260,256,8,500,506,10,509,13,12,143,274,17,405,393,547,21,267,553,286,29,541,281,430,279,34,167,152,285,38,39,305,306,577,44,573,47,574,172,176,294,52,183,54,55,316,320,559,561,440,200,74,78,325,459,214,460,90,338,227,361,352,244,114,237,364,248,257 | 2751,1207,2321,3065,646,2408,2047,176,2793,1954,1003,1283,325,13,2754,55,1534,2795,2219,21,2646,294,393,1368,3483,2137,1450,248,3068,1218,214,1698,1372,152,2053,47,500,2705,559,74,2967,703,1962,2054,3149,29,1873,3218,2141,1012,3191,3151,3106,1374,704,1618,1144,3572,1291,3256,279,338,840,2331,1145,2223,172,3406,3544,242... | -0.4587663248239629,0.15884550726049723,-0.2609563355332265,-0.6593637349435877,0.47430803058067816,-0.29373844618932715,-0.16304347134508207,1.446478167816503,-0.4920008457387619,-0.13054795621506413,0.25413257026133235,0.12695555655645674,0.9366227945511973,5.243267115697605,-0.4587663248239629,2.6800374279695216,0.0... | 3,643 |
Glycosidase | 9 | 20 | 2.241447 | 0.024997 | P16278,O00754,P04066,Q9BTY2,O60476,P10253,O60502,P54802,P06280 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 155,435,228,115,264,266,84,147,153 | 435,1282,264,84,703,228,153,1013,3538,455,266,155,1383,1623,147,1892,3490,1997,3205,115 | 0.7224199472328477,0.12695555655645674,1.0578712931665288,2.144013371443563,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,-1.3862754857551036,0.6916031594494587,1.0578712931665288,1.5350292358486646,0.09500082791205905,-0.0012581004565036626,1.5644560394229112,-0.098122333905974,-1.20942... | 3,643 |
Neuromuscular junction | 6 | 20 | 2.240742 | 0.025043 | Q7L0J3,P57105,Q14168,P07196,P05067,P46939 | Localization | GO Cellular component | msigdb_gocc | 17,238,211,125,29,281 | 1533,29,3218,125,1377,3257,3406,280,3117,281,238,3079,1398,211,1166,418,1096,17,2898,2619 | 0.030894617027511038,3.6353042018995785,-0.7947358122572576,1.7400910153055076,0.09500082791205905,-0.8287924672030076,-1.0350054838275398,1.027635769907882,-0.6930805097254553,1.027635769907882,1.1482768495977804,-0.6593637349435877,0.09500082791205905,1.268129085929357,0.19067127264620573,0.7531817696547146,0.2224334... | 3,643 |
Vitamin transport | 7 | 10 | 2.237164 | 0.025276 | P11166,Q9H2D1,Q8WTV0,O14678,Q9NPF0,Q9HC21,P41440 | Processes and pathways | GO Biological process | msigdb_gobp | 279,733,8,176,492,553,90 | 176,703,279,2342,847,90,8,733,553,492 | 1.446478167816503,0.44303477605405855,1.027635769907882,-0.2609563355332265,0.34885740302862467,2.058127752852981,5.940175937290734,0.44303477605405855,0.5988184783374502,0.6607309570482511 | 3,643 |
Overlap between signal transduction pathways contributing to lmna laminopathies | 9 | 15 | 2.234049 | 0.02548 | P11802,P48729,P49354,Q9Y2U8,P02545,P42166,O75844,O60725,P35222 | Processes and pathways | WikiPathways | msigdb_wp | 841,439,229,744,265,793,248,587,708 | 587,248,265,841,708,793,2344,439,229,1801,849,1232,1816,1689,744 | 0.5366787829519797,1.118191455601226,1.0578712931665288,0.34885740302862467,0.44303477605405855,0.3803099800917596,-0.2609563355332265,0.7224199472328477,1.1783129469800828,-0.06576592628969985,0.34885740302862467,0.15884550726049723,-0.06576592628969985,-0.0012581004565036626,0.44303477605405855 | 3,643 |
Interferon gamma signaling | 6 | 14 | 2.232611 | 0.025575 | P19474,O15344,P10321,Q13555,P30511,P29372 | Processes and pathways | Reactome Pathways | msigdb_reactome | 36,253,532,105,138,438 | 253,1872,590,532,1794,36,438,138,756,2938,1815,2441,105,1563 | 1.08805639508316,-0.098122333905974,0.5366787829519797,0.5988184783374502,-0.06576592628969985,3.3662912544280115,0.7224199472328477,1.623176179314646,0.4117022638315761,-0.5587053640309138,-0.06576592628969985,-0.29373844618932715,1.943054324684516,0.030894617027511038 | 3,643 |
Cell activation involved in immune response | 14 | 42 | 2.23078 | 0.025696 | Q92538,Q9UQ84,Q15046,Q96FV9,P51809,P02786,P30511,Q9NQT5,P11274,O95219,P00813,Q9NRA0,O96028,P05067 | Processes and pathways | GO Biological process | msigdb_gobp | 515,33,566,681,476,409,138,638,338,235,56,227,87,29 | 1207,2860,1217,235,87,56,409,2508,1288,29,1081,653,3256,338,1082,3591,3513,1084,138,1296,1086,1548,476,1553,1233,1893,1727,2526,566,2532,2535,969,1737,515,681,914,1928,638,227,3098,1855,33 | 0.15884550726049723,-0.525313577596298,0.15884550726049723,1.1482768495977804,2.11542427763213,2.6800374279695216,0.7531817696547146,-0.3265940252928932,0.12695555655645674,3.6353042018995785,0.2224334357534765,0.47430803058067816,-0.8287924672030076,0.9061816816409076,0.2224334357534765,-1.7470088834303552,-1.27987528... | 3,643 |
Postural tremor | 8 | 21 | 2.228565 | 0.025843 | Q9NR77,P03886,P20700,Q14108,O75569,P00846,O75306,O14773 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,62,310,255,350,74,471,391 | 391,1210,471,350,791,1782,2705,74,62,2967,2654,310,754,1387,955,255,3177,2112,579,32,2562 | 0.7838890695289682,0.15884550726049723,0.6607309570482511,0.8756881681175116,0.3803099800917596,-0.06576592628969985,-0.42560918711049844,2.371337868662573,2.512197372488192,-0.5921770650124923,-0.3925286203228279,0.9670119136618348,0.4117022638315761,0.09500082791205905,0.2857692407025649,1.08805639508316,-0.726880811... | 3,643 |
Abnormality of the shoulder girdle musculature | 11 | 38 | 2.226974 | 0.025949 | P07602,Q9Y487,Q8TD16,Q7LG56,Q14331,P02545,P06753,Q9H9S5,Q96RR1,Q13049,P07196 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 69,43,272,464,477,265,394,347,319,188,125 | 2210,1605,1000,2502,529,1005,2136,3404,2412,265,394,125,69,3257,2331,2337,890,2432,849,2242,2349,1815,2358,188,959,477,464,272,976,319,1581,347,1064,2490,43,1604,1068,1069 | -0.22824695247054547,-0.0012581004565036626,0.25413257026133235,-0.3265940252928932,0.5988184783374502,0.25413257026133235,-0.19560956934146895,-1.0350054838275398,-0.29373844618932715,1.0578712931665288,0.7838890695289682,1.7400910153055076,2.427791890653298,-0.8287924672030076,-0.2609563355332265,-0.2609563355332265,... | 3,643 |
Intermediate filament protein, conserved site [IPR018039] | 6 | 8 | 2.226422 | 0.025986 | P07197,P20700,P08670,Q03252,P02545,P07196 | Sequence | InterPro Conserved site | interpro_conserved_site | 221,310,104,207,265,125 | 265,125,221,104,310,757,207,510 | 1.0578712931665288,1.7400910153055076,1.2083001127798034,1.943054324684516,0.9670119136618348,0.4117022638315761,1.2979715997804608,0.6298028841948623 | 3,643 |
Intermediate filament, rod domain [IPR039008] | 6 | 8 | 2.226422 | 0.025986 | P07197,P20700,P08670,Q03252,P02545,P07196 | Sequence | InterPro Domain | interpro_domain | 221,310,104,207,265,125 | 265,125,221,104,310,757,207,510 | 1.0578712931665288,1.7400910153055076,1.2083001127798034,1.943054324684516,0.9670119136618348,0.4117022638315761,1.2979715997804608,0.6298028841948623 | 3,643 |
Positive regulation of immune response | 22 | 82 | 2.22455 | 0.026111 | P46379,P49770,P30511,Q06481,Q9BY67,P02786,Q7Z434,P00813,P23396,Q15046,Q15233,P12956,P04439,O96028,O15400,Q9NRA0,Q9NUQ9,P51809,Q9NQT5,O95219,P26583,P23246 | Processes and pathways | GO Biological process | msigdb_gobp | 3,618,138,39,304,409,420,56,437,566,567,83,590,87,586,227,102,476,638,235,616,375 | 2050,586,2502,2860,2794,1698,1616,235,87,56,1872,409,2508,590,1789,1081,3256,1704,1082,83,1146,941,1084,2427,375,437,616,3197,138,2229,3297,1547,890,1548,3117,3,618,3344,476,3160,3118,1390,2938,39,1310,623,1394,1395,1727,2526,1645,1479,1818,566,567,1037,1404,2535,969,420,1111,1923,914,1339,1261,1928,1506,3177,3235,919,... | -0.16304347134508207,0.5366787829519797,-0.3265940252928932,-0.525313577596298,-0.4920008457387619,-0.03347806686168351,-0.0012581004565036626,1.1482768495977804,2.11542427763213,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,-0.06576592628969985,0.2224334357534765,-0.82... | 3,643 |
Mitochondrial carrier domain superfamily [IPR023395] | 10 | 24 | 2.224473 | 0.026117 | Q9BSK2,Q86VD7,Q70HW3,Q9UBX3,Q96H78,Q9BQT8,O43772,Q9HC21,Q9Y619,Q9Y6C9 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 260,256,285,306,274,577,13,553,693,695 | 13,2754,1450,1873,2331,1145,2073,2812,2771,2274,2366,285,256,1502,274,577,260,733,553,1064,306,924,693,695 | 5.243267115697605,-0.4587663248239629,0.06298071889501843,-0.098122333905974,-0.2609563355332265,0.19067127264620573,-0.16304347134508207,-0.4920008457387619,-0.4587663248239629,-0.22824695247054547,-0.2609563355332265,1.027635769907882,1.08805639508316,0.06298071889501843,1.0578712931665288,0.5677772700633923,1.088056... | 3,643 |
Mitochondrial substrate/solute carrier [IPR018108] | 10 | 24 | 2.224473 | 0.026117 | Q9BSK2,Q86VD7,Q70HW3,Q9UBX3,Q96H78,Q9BQT8,O43772,Q9HC21,Q9Y619,Q9Y6C9 | Sequence | InterPro Repeat | interpro_repeat | 260,256,285,306,274,577,13,553,693,695 | 13,2754,1450,1873,2331,1145,2073,2812,2771,2274,2366,285,256,1502,274,577,260,733,553,1064,306,924,693,695 | 5.243267115697605,-0.4587663248239629,0.06298071889501843,-0.098122333905974,-0.2609563355332265,0.19067127264620573,-0.16304347134508207,-0.4920008457387619,-0.4587663248239629,-0.22824695247054547,-0.2609563355332265,1.027635769907882,1.08805639508316,0.06298071889501843,1.0578712931665288,0.5677772700633923,1.088056... | 3,643 |
SLC25 family of mitochondrial transporters | 10 | 24 | 2.224473 | 0.026117 | Q9BSK2,Q86VD7,Q70HW3,Q9UBX3,Q96H78,Q9BQT8,O43772,Q9HC21,Q9Y619,Q9Y6C9 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 260,256,285,306,274,577,13,553,693,695 | 13,2754,1450,1873,2331,1145,2073,2812,2771,2274,2366,285,256,1502,274,577,260,733,553,1064,306,924,693,695 | 5.243267115697605,-0.4587663248239629,0.06298071889501843,-0.098122333905974,-0.2609563355332265,0.19067127264620573,-0.16304347134508207,-0.4920008457387619,-0.4587663248239629,-0.22824695247054547,-0.2609563355332265,1.027635769907882,1.08805639508316,0.06298071889501843,1.0578712931665288,0.5677772700633923,1.088056... | 3,643 |
Regulation of immune response | 34 | 136 | 2.216455 | 0.02666 | Q07666,P23246,P46379,P30511,Q5KU26,P14373,Q8TCT8,P19474,Q06481,Q9BY67,P28070,P02786,Q7Z434,Q9NPR9,P00813,O43657,P23396,Q15046,Q15233,P12956,P04439,O96028,O15400,P41440,P11274,Q9NRA0,Q9NUQ9,P51809,Q9NZ08,Q9NQT5,O95219,O75955,P26583,P49770 | Processes and pathways | GO Biological process | msigdb_gobp | 623,375,3,138,396,395,158,36,39,304,164,409,420,48,56,557,437,566,567,83,590,87,586,90,338,227,102,476,245,638,235,249,616,618 | 1952,1209,2050,586,1695,2501,2502,557,2860,2794,2796,3216,249,1698,1616,235,87,56,1872,409,2508,590,1789,1457,1081,653,2511,3256,1704,338,1082,83,1146,395,941,1084,1794,2427,36,375,437,2762,616,164,3197,138,3520,2229,3297,1547,90,890,1548,2712,3117,3,618,3344,476,3626,797,3160,3118,2436,1390,3038,2938,1815,39,1310,623,... | -0.13054795621506413,0.15884550726049723,-0.16304347134508207,0.5366787829519797,-0.03347806686168351,-0.3265940252928932,-0.3265940252928932,0.5677772700633923,-0.525313577596298,-0.4920008457387619,-0.4920008457387619,-0.7947358122572576,1.118191455601226,-0.03347806686168351,-0.0012581004565036626,1.1482768495977804... | 3,643 |
Clathrin coated vesicle | 12 | 55 | 2.210709 | 0.027056 | P11717,Q14108,P20645,P02786,Q9Y5X1,O43493,Q99523,O43752,P42892,O00291,Q5VW38,Q9NUN5 | Localization | GO Cellular component | msigdb_gocc | 154,255,37,409,107,142,114,454,53,390,23,123 | 1770,1952,390,834,1444,142,2860,454,1213,1367,2798,2328,3617,409,1702,1703,2144,154,2578,37,53,795,1155,2347,1887,476,2348,2805,2075,3571,2251,952,2257,2596,255,2088,902,3083,23,3355,2180,1050,114,2627,1933,1349,1936,1844,123,3313,2633,3063,1595,107,1525 | -0.06576592628969985,-0.13054795621506413,0.7838890695289682,0.34885740302862467,0.06298071889501843,1.5938382520831849,-0.525313577596298,0.6916031594494587,0.15884550726049723,0.09500082791205905,-0.4920008457387619,-0.2609563355332265,-2.342454069604444,0.7531817696547146,-0.03347806686168351,-0.03347806686168351,-0... | 3,643 |
Ciliary transition zone | 6 | 11 | 2.209134 | 0.027165 | Q15051,Q15555,O15078,A6NIH7,Q9Y366,Q9UPN4 | Localization | GO Cellular component | msigdb_gocc | 223,355,194,46,290,388 | 46,194,3296,2151,1486,223,1243,355,519,388,290 | 3.0942250631129866,1.3575144142492008,-0.8629365633590367,-0.19560956934146895,0.06298071889501843,1.2083001127798034,0.15884550726049723,0.8756881681175116,0.6298028841948623,0.8145422833591529,1.027635769907882 | 3,643 |
Impaired pain sensation | 11 | 21 | 2.208147 | 0.027234 | Q9NR77,Q13045,O15269,O95714,O95831,O95140,P39210,P07196,P17480,Q14683,Q00796 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,507,746,652,47,791,267,125,591,899,156 | 746,2212,791,1454,652,47,125,591,1878,267,1467,1301,2349,3471,1809,156,507,899,1825,980,32 | 0.4117022638315761,-0.22824695247054547,0.3803099800917596,0.06298071889501843,0.47430803058067816,3.0119856905575273,1.7400910153055076,0.5366787829519797,-0.098122333905974,1.0578712931665288,0.06298071889501843,0.12695555655645674,-0.2609563355332265,-1.174345720866778,-0.06576592628969985,1.5350292358486646,0.62980... | 3,643 |
Regulation of adaptive immune response | 9 | 24 | 2.206549 | 0.027346 | Q9NUQ9,P02786,P30511,Q9NQT5,P14373,P04439,P00813,O15400,O96028 | Processes and pathways | GO Biological process | msigdb_gobp | 102,409,138,638,395,590,56,586,87 | 586,2502,87,56,1872,409,2508,590,1081,3256,395,138,1548,2526,1404,2535,969,1737,1923,681,914,1928,638,102 | 0.5366787829519797,-0.3265940252928932,2.11542427763213,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.2224334357534765,-0.8287924672030076,0.7838890695289682,1.623176179314646,0.030894617027511038,-0.3265940252928932,0.09500082791205905,-0.3265940252928932,0.285769240... | 3,643 |
Neutrophil degranulation | 35 | 184 | 2.205526 | 0.027417 | P42785,P78371,P84095,P20618,P30519,P14174,Q8N2G8,P10253,P06280,P16278,P11717,O00231,Q8WVQ1,Q07065,O75787,P15586,Q92542,P10619,Q13813,O00754,P07602,O15078,Q13464,Q93050,P12956,Q7L576,P04066,O00584,P61916,O15260,Q9BTY2,P15291,O43681,Q99436,Q9NQX7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 4,378,139,137,14,15,398,266,153,155,154,278,423,173,296,410,317,59,315,435,69,194,328,82,83,340,228,103,351,108,115,112,118,121,122 | 278,3316,932,1135,2322,1209,103,435,611,194,108,1609,118,1534,2700,1078,296,1284,2798,3103,1456,2704,2757,1872,228,2922,2758,590,153,1011,2509,1012,3191,3151,1701,69,3538,2510,1789,455,1457,3528,1081,2222,3435,2511,266,532,59,3219,2144,1964,1082,154,3193,83,1146,2332,1876,3109,15,2868,3468,112,410,3552,155,1965,2869,10... | 1.027635769907882,-0.8971691305719629,0.2857692407025649,0.19067127264620573,-0.2609563355332265,0.15884550726049723,1.943054324684516,0.7224199472328477,0.5055225334229401,1.3575144142492008,1.914184390727662,-0.0012581004565036626,1.7982903969638317,0.030894617027511038,-0.42560918711049844,0.2224334357534765,0.99734... | 3,643 |
Abnormality of the calf | 20 | 71 | 2.202723 | 0.027614 | Q7RTS9,Q13126,Q9NR77,P16278,Q8WVQ1,Q8N0X7,Q96L58,O75718,O95831,O00754,Q15056,P08236,O75431,P51798,Q9NX62,Q9NWH9,Q01082,Q96HY6,Q9NUQ7,Q9UIG0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 11,20,32,155,423,421,303,295,47,435,462,455,213,460,231,371,365,384,524,527 | 3186,435,1610,2861,2412,499,213,295,3288,1784,652,47,2651,1288,455,3108,155,2145,3406,2337,1710,2147,707,3199,1973,2765,2933,1886,460,1089,365,2257,2258,1893,20,900,462,2887,3302,2728,3304,3413,11,2458,421,1500,3132,2610,423,2612,384,303,728,3575,3001,2195,3096,32,3006,524,3182,371,231,1852,527,2041,2854,2960,1603,1069... | -0.7607655898218467,0.7224199472328477,-0.0012581004565036626,-0.525313577596298,-0.29373844618932715,0.6298028841948623,1.2382387072449188,0.9973494401983068,-0.8629365633590367,-0.06576592628969985,0.47430803058067816,3.0119856905575273,-0.3925286203228279,0.12695555655645674,0.6916031594494587,-0.6930805097254553,1.... | 3,643 |
Vascular skin abnormality | 29 | 135 | 2.200119 | 0.027798 | P22830,Q14108,Q8IZA0,Q8WVM7,P02545,Q13126,O00192,Q9UBM7,P06280,P16278,P35579,Q8NCH0,Q96L58,Q9Y487,Q96JJ3,Q14739,Q969N2,P10619,P03886,O95155,P00846,P51798,P78536,Q9UQE7,P04066,O75306,Q15437,Q14331,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,255,141,400,265,20,389,289,153,155,280,422,303,43,302,416,318,59,62,307,74,460,216,496,228,471,110,477,248 | 1281,389,1210,1696,1958,1777,1960,1614,471,3363,248,307,2650,1141,2705,559,74,1872,265,62,2967,703,228,153,2055,1792,59,1377,2512,3108,3552,155,942,3406,2925,1222,2337,1796,2515,0,2658,888,3197,2581,592,1881,708,280,1624,3382,847,2661,1296,1019,2933,3557,794,2236,1885,2583,460,3626,948,2074,2158,1387,797,3571,216,1477,... | 0.12695555655645674,0.7838890695289682,0.15884550726049723,-0.03347806686168351,-0.13054795621506413,-0.06576592628969985,-0.13054795621506413,-0.0012581004565036626,0.6607309570482511,-0.9659039071751861,1.118191455601226,0.9670119136618348,-0.3925286203228279,0.19067127264620573,-0.42560918711049844,0.567777270063392... | 3,643 |
Abnormality of extrapyramidal motor function | 21 | 80 | 2.199378 | 0.027851 | Q99720,P98175,O96008,P06753,P05067,P16278,P11166,O75787,Q14203,O75251,Q9H6K4,Q9BPX6,Q96RR1,Q6DKK2,P07602,Q15056,Q7LG56,Q9Y4W6,O75569,Q9NWW5,Q9UIG0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 2,134,500,394,29,155,279,296,415,294,579,320,319,190,69,462,464,608,350,251,527 | 2499,1610,1078,294,350,296,3363,500,3147,703,29,394,1013,69,3538,1875,279,841,2331,155,591,2869,2925,1222,2225,3113,1713,3199,3153,1225,754,3325,1301,2242,1088,2349,797,1984,1089,134,2080,2721,955,1895,1992,415,3123,963,462,807,190,2893,1827,464,3132,2011,2108,2624,1675,319,3176,3177,2,320,1755,1423,579,2118,3535,251,1... | -0.3265940252928932,-0.0012581004565036626,0.2224334357534765,0.9973494401983068,0.8756881681175116,0.9973494401983068,-0.9659039071751861,0.6298028841948623,-0.726880811724572,0.44303477605405855,3.6353042018995785,0.7838890695289682,0.25413257026133235,2.427791890653298,-1.3862754857551036,-0.098122333905974,1.027635... | 3,643 |
Gait ataxia | 21 | 77 | 2.198657 | 0.027902 | Q14108,O15118,O14773,Q9P0J1,Q9NR77,Q5THJ4,Q96RR1,Q5H8A4,P03886,P20700,O00754,P07602,Q8IV08,P00846,Q7LG56,Q03252,Q9Y4W6,P41440,P17480,O43681,P07196 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 255,252,391,689,32,668,319,569,62,310,435,69,73,74,464,207,608,90,591,118,125 | 1862,435,391,2571,252,2216,118,2503,74,62,2967,2654,125,3151,69,2512,2331,1876,591,2925,1222,2225,310,1798,3028,844,2972,753,1971,2431,1975,90,2713,1885,1301,2238,2242,1387,797,2768,207,955,658,1238,1562,3328,1646,255,899,1565,3124,1404,569,668,2452,1407,464,73,3393,2830,1050,2832,980,2622,319,3210,32,1197,1849,1850,10... | -0.098122333905974,0.7224199472328477,0.7838890695289682,-0.3595238272390506,1.08805639508316,-0.22824695247054547,1.7982903969638317,-0.3265940252928932,2.371337868662573,2.512197372488192,-0.5921770650124923,-0.3925286203228279,1.7400910153055076,-0.726880811724572,2.427791890653298,-0.3265940252928932,-0.26095633553... | 3,643 |
Early endosome | 35 | 118 | 2.19737 | 0.027994 | Q8WUH2,Q9HD42,Q9HC07,Q96C92,P30511,Q96PE3,P14373,Q5VW38,P05067,Q9Y5X2,P11717,Q8N4V1,P10321,Q06481,Q9UIQ6,P02786,Q96L92,Q9Y6W5,Q92542,Q8IV08,P51790,O43752,P61020,P04439,O15400,P41440,Q9H223,Q567U6,Q15075,Q86YV9,Q99523,P31751,O95219,O75955,Q9NWW5 | Localization | GO Cellular component | msigdb_gocc | 133,276,405,273,138,402,395,23,29,433,154,167,532,39,42,409,575,583,317,73,459,454,596,590,586,90,490,224,354,479,114,364,235,249,251 | 3141,2321,1606,1774,586,454,1004,1213,588,1078,3361,249,938,235,885,3617,1872,409,2508,590,29,532,3256,154,395,1794,1879,2578,3322,3073,3197,1149,138,3407,364,2229,1019,90,655,1300,459,596,2075,2587,3077,1557,2257,2258,39,801,2596,3473,1030,3348,2361,2530,963,354,2269,1166,224,2093,767,23,1655,1494,2823,810,479,73,167,... | -0.726880811724572,-0.2609563355332265,-0.0012581004565036626,-0.06576592628969985,0.5366787829519797,0.6916031594494587,0.25413257026133235,0.15884550726049723,0.5366787829519797,0.2224334357534765,-0.9659039071751861,1.118191455601226,0.2857692407025649,1.1482768495977804,0.31734400267200297,-2.342454069604444,-0.098... | 3,643 |
Abnormal enchondral ossification | 9 | 30 | 2.196065 | 0.028087 | O00116,Q8WVQ1,Q96L58,Q7RTS9,Q14739,P08236,Q96HY6,O96028,Q9UBM7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 374,423,303,11,416,455,384,87,289 | 374,2412,3483,1372,87,455,1377,2337,1973,847,1464,1802,2434,1562,3328,416,900,1566,2364,11,1500,423,2183,384,303,524,289,2400,3012,693 | 0.8145422833591529,-0.29373844618932715,-1.209424370050621,0.09500082791205905,2.11542427763213,0.6916031594494587,0.09500082791205905,-0.2609563355332265,-0.13054795621506413,0.34885740302862467,0.06298071889501843,-0.06576592628969985,-0.29373844618932715,0.030894617027511038,-0.8971691305719629,0.7531817696547146,0.... | 3,643 |
Metalloprotease | 7 | 28 | 2.195779 | 0.028108 | P52888,Q9UIQ6,Q9NZ08,O75976,P42892,P78536,P55786 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 98,42,245,206,53,216,31 | 1135,1137,2137,248,206,885,2222,3108,2760,53,98,31,216,1042,2776,1322,3133,1188,1264,2737,1422,3554,386,3241,3137,245,42,608 | 0.19067127264620573,0.19067127264620573,-0.19560956934146895,1.118191455601226,1.2979715997804608,0.31734400267200297,-0.22824695247054547,-0.6930805097254553,-0.4587663248239629,2.763483088965262,1.9718833674139287,3.6085359292973544,1.2382387072449188,0.25413257026133235,-0.4587663248239629,0.12695555655645674,-0.693... | 3,643 |
Glycoside hydrolase superfamily [IPR017853] | 8 | 16 | 2.194623 | 0.028191 | P16278,P04066,Q9BTY2,P08236,P10253,O60502,P54802,P06280 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 155,228,115,455,266,84,147,153 | 84,703,228,153,1013,3538,704,455,266,155,1623,147,1997,478,115,3002 | 2.144013371443563,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,-1.3862754857551036,0.44303477605405855,0.6916031594494587,1.0578712931665288,1.5350292358486646,-0.0012581004565036626,1.5644560394229112,-0.13054795621506413,0.6607309570482511,1.8563207862044178,-0.5921770650124923 | 3,643 |
Disproportionate short limb short stature | 7 | 22 | 2.189929 | 0.028529 | O00116,Q8WVQ1,Q7RTS9,Q15392,O75718,Q9Y366,Q9UBM7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 374,423,11,45,295,290,289 | 374,584,2412,295,3288,1377,2516,1086,2713,1403,416,45,2728,1172,3413,11,1500,423,2183,3001,289,290 | 0.8145422833591529,0.5366787829519797,-0.29373844618932715,0.9973494401983068,-0.8629365633590367,0.09500082791205905,-0.3265940252928932,0.2224334357534765,-0.42560918711049844,0.09500082791205905,0.7531817696547146,3.1215736355280526,-0.42560918711049844,0.19067127264620573,-1.0350054838275398,5.543953911878619,0.062... | 3,643 |
Enzyme linked receptor protein signaling pathway | 25 | 131 | 2.185938 | 0.02882 | Q8WUH2,Q92896,Q8N3R9,O00291,Q9UQB8,P11717,Q06481,Q9UIQ6,Q8N0X7,Q15375,P43490,Q96TA1,Q9Y4G8,Q96F07,Q13573,Q8N1F7,P78536,Q7L576,P49354,P08670,Q9NWH9,Q99523,Q01082,P31751,P10586 | Processes and pathways | GO Biological process | msigdb_gobp | 133,136,148,390,26,154,39,42,421,418,71,333,81,344,88,342,216,340,229,104,371,114,365,364,119 | 2132,390,646,834,2322,788,2793,1606,2049,1774,3101,2502,2700,1367,3404,701,1288,1289,3218,1457,104,1791,119,154,841,2760,3629,2425,1459,1794,2427,3322,3073,3197,592,364,3520,1384,708,2431,1296,71,2712,3117,709,229,2519,1801,1155,2156,3344,3299,2075,2436,1389,1156,1025,216,365,1893,2938,2081,1815,39,1479,1994,2671,88,32... | -0.19560956934146895,0.7838890695289682,0.47430803058067816,0.34885740302862467,-0.2609563355332265,0.3803099800917596,-0.4920008457387619,-0.0012581004565036626,-0.16304347134508207,-0.06576592628969985,-0.6930805097254553,-0.3265940252928932,-0.42560918711049844,0.09500082791205905,-1.0350054838275398,0.4430347760540... | 3,643 |
Basal part of cell | 17 | 61 | 2.184376 | 0.028935 | P11166,P42785,Q9BY67,P02786,P53985,Q9NWH9,Q96N67,Q01650,Q14168,P15291,Q6P4Q7,P57105,P30825,O75955,P41440,Q9Y6M7,O14936 | Localization | GO Cellular component | msigdb_gocc | 279,4,304,409,44,371,401,143,211,112,316,238,54,249,90,361,436 | 2132,1207,436,1003,3496,249,938,3617,409,2508,1962,2054,3149,3191,704,1457,279,3023,2760,112,941,3552,942,843,1015,2517,501,54,3520,2342,708,889,90,4,44,3075,440,238,3546,2162,143,2259,1029,1727,1398,2267,211,1315,963,662,1041,316,1323,3173,401,863,2292,304,371,361,583 | -0.19560956934146895,0.15884550726049723,0.7224199472328477,0.25413257026133235,-1.244601121096576,1.118191455601226,0.2857692407025649,-2.342454069604444,0.7531817696547146,-0.3265940252928932,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,-0.7607655898218467,0.44303477605405855,0.06298071889501843,1.027... | 3,643 |
Splenomegaly | 24 | 98 | 2.183088 | 0.029029 | Q14108,O15118,P14174,P02545,P10253,P54802,O00192,P16278,P11166,P28070,Q15392,P15586,Q14739,P00813,O14936,O00754,P07602,P08236,P11274,P04066,P61916,Q9NZ08,Q15437,Q96HY6 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 255,252,15,265,266,147,389,155,279,164,45,410,416,56,436,435,69,455,338,228,351,245,110,384 | 389,1952,834,435,2792,436,252,1777,1960,2646,748,3363,1141,2757,56,1872,265,703,228,2922,1288,3366,2509,2055,69,455,266,279,3023,2969,338,840,3108,15,410,155,842,1878,2061,2515,2428,2658,164,1622,2659,592,1714,1544,3382,3578,2933,2236,1020,2238,460,2074,2716,147,3408,351,2591,2256,1893,2938,658,803,3473,2672,255,416,45... | 0.7838890695289682,-0.13054795621506413,0.34885740302862467,0.7224199472328477,-0.4920008457387619,0.7224199472328477,1.08805639508316,-0.06576592628969985,-0.13054795621506413,-0.3925286203228279,0.4117022638315761,-0.9659039071751861,0.19067127264620573,-0.4587663248239629,2.6800374279695216,-0.098122333905974,1.0578... | 3,643 |
Abnormal acetabulum morphology | 7 | 24 | 2.180259 | 0.029238 | P16278,Q8WVQ1,Q96L58,Q7RTS9,O75718,P08236,Q9Y366 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 155,423,303,11,295,455,290 | 2321,1952,2412,295,1784,455,155,2765,2352,1989,806,1905,11,1500,423,3231,2180,1112,303,3096,524,2041,290,2316 | -0.2609563355332265,-0.13054795621506413,-0.29373844618932715,0.9973494401983068,-0.06576592628969985,0.6916031594494587,1.5350292358486646,-0.4587663248239629,-0.2609563355332265,-0.13054795621506413,0.3803099800917596,-0.098122333905974,5.543953911878619,0.06298071889501843,0.7531817696547146,-0.7947358122572576,-0.1... | 3,643 |
Organelle inner membrane | 84 | 224 | 5.138736 | 0 | Q567V2,O60830,Q96CU9,Q99720,Q13505,O76031,O43772,Q9UDW1,P14406,O43676,Q9H2D1,Q99595,O95831,Q70HW3,O95202,O95168,O75844,Q13423,Q96DV4,Q9BRJ2,Q9BSK2,Q9BYC9,Q14739,Q9Y619,Q9H2W6,Q7KZN9,O75306,Q9BQT8,Q9UBX3,Q9UDX5,O75964,Q5SNT2,Q9Y6C9,Q9H061,Q9Y2R0,P53701,Q6UXV4,Q9P032,P49748,Q10713,P15954,O43819,O75027,O95299,P12236,P2378... | Localization | GO Cellular component | msigdb_gocc | 2,8,9,13,15,508,26,42,44,46,50,56,58,64,555,554,68,77,621,622,623,625,91,92,627,95,97,109,110,111,106,118,128,126,138,135,141,687,148,661,648,640,641,642,647,650,659,663,185,723,724,700,712,225,699,221,243,246,264,258,299,305,335,330,321,325,353,351,348,372,368,362,402,409,388,431,438,426,417,499,502,488,486,473 | 3175,1790,321,362,853,46,26,640,1461,8,641,1975,1068,97,998,1069,1887,1888,473,243,68,2335,1223,106,508,258,554,1379,555,642,859,58,800,699,1074,2488,2734,1159,1544,1633,1988,2178,2618,1161,647,2970,388,44,2868,648,299,1637,2561,2082,2562,1315,700,417,2870,2263,650,1163,2682,2625,745,1083,2829,2089,2000,1556,2831,1084,... | -2.537457890708034,-0.17716618352898394,0.8217925949426864,0.7497224929294436,0.30141428148632216,2.6081164823979903,3.481516904512842,0.4540235095844826,-0.014168302611951702,5.710127312386168,0.4540235095844826,-0.25994298419798034,0.1847155783283068,1.7328021609675641,0.22383486656935098,0.1847155783283068,-0.218448... | 3,193 |
Endoplasmic reticulum | 109 | 464 | 4.918473 | 0.000001 | Q9H6V9,Q14108,P30519,P80303,Q99720,P43307,Q9BQE5,Q9UQB8,P24390,Q5BJF2,O60725,Q03518,Q06136,P09601,P30536,Q02818,Q9HD20,Q9BZF3,Q96G23,O75844,Q15392,P13674,Q8TDW0,Q16880,Q15629,P35610,Q7L0J3,P10619,Q14739,Q9Y680,Q12959,Q9UMX5,Q13555,P42858,O75845,Q16850,O75503,Q9UKR5,P48449,Q9NZ08,O43731,Q9BRK5,Q15800,O95864,Q14257,P6226... | Localization | GO Cellular component | msigdb_gocc | 1,6,7,12,13,16,19,21,22,23,29,30,31,35,53,55,59,62,65,68,75,80,81,86,85,84,88,90,91,101,103,112,108,107,105,115,116,127,121,133,139,147,150,153,157,162,166,168,175,186,184,191,199,195,194,209,202,201,223,221,222,217,213,235,227,248,251,250,245,270,259,288,292,286,278,283,309,310,316,328,322,319,361,350,349,348,373,371,... | 470,1061,1877,637,1969,1219,2925,2164,2771,471,2990,319,928,1972,2330,2481,589,441,3131,851,996,2550,201,789,2332,693,2671,2993,694,139,322,2607,2070,1716,795,2672,29,1067,2552,695,796,1540,116,1796,385,68,105,507,856,1225,697,1226,2612,2171,2554,1979,2775,1889,2172,1799,799,1228,213,698,859,1722,153,2733,1380,645,2968... | 0.603398739242378,0.1847155783283068,-0.21844879395768765,0.4540235095844826,-0.25994298419798034,0.10581674080916348,-0.9072118013025617,-0.34356283749264765,-0.7301162059779877,0.603398739242378,-1.0421318380239888,0.8217925949426864,0.26273353937402294,-0.25994298419798034,-0.4280193129695504,-0.5133061398194652,0.4... | 3,193 |
Transporter activity | 44 | 161 | 4.74982 | 0.000002 | Q96ES6,O60830,P04062,Q8NBU5,Q99808,Q9Y6M7,O43772,Q03518,Q8IXU6,P21796,Q99797,Q9NS69,Q9UDW1,P51798,O43676,Q9H2D1,Q6N075,Q8WTV0,P30536,Q99595,Q9HD20,Q9BZF3,Q15388,Q70HW3,P45880,Q9Y487,Q9C0H2,Q13423,O14925,Q8TDW0,P53007,Q7L0J3,Q9HC07,Q9Y619,Q7KZN9,O75306,P53985,Q9BQT8,Q9UBX3,O75964,Q93050,O75746,P08183,Q14728 | Functions | GO Molecular function | msigdb_gomf | 5,8,259,263,289,25,26,30,36,37,166,41,42,170,46,50,172,51,53,56,59,62,304,64,69,73,76,77,321,81,325,88,89,92,95,97,102,109,110,106,252,243,120,246 | 636,3175,2950,1790,2991,321,2481,589,46,694,26,638,8,641,1068,97,998,1888,243,1223,106,1309,554,1379,555,642,800,699,259,2255,3167,1074,2488,2677,2929,120,1464,1159,3111,2178,2778,1161,647,388,1805,2780,2561,2181,2082,2182,2739,37,1388,1163,2682,743,2625,53,1083,1811,2000,2745,868,2630,1733,69,808,2354,2270,1090,2091,3... | 0.4540235095844826,-2.537457890708034,-0.9519864382224174,-0.17716618352898394,-1.0421318380239888,0.8217925949426864,-0.5133061398194652,0.49166307589473773,2.6081164823979903,0.41618190889414125,3.481516904512842,0.4540235095844826,5.710127312386168,0.4540235095844826,0.1847155783283068,1.7328021609675641,0.223834866... | 3,193 |
Organelle subcompartment | 93 | 357 | 4.61821 | 0.000004 | Q9NQC3,Q14108,P30519,Q99720,P43307,Q9BQE5,P24390,Q5BJF2,O60725,Q03518,Q06136,P09601,Q9HD20,Q9BZF3,Q96G23,Q969E2,O75844,Q15392,Q8TDW0,Q15629,P35610,Q9HC07,Q14739,Q16706,O00461,Q12959,Q13555,O75845,Q16850,Q9UKR5,P48449,Q9NZ08,Q12893,O43731,Q15800,O95864,Q9UBV2,Q9BRR6,Q9Y282,Q9BUN8,Q8TCJ2,P06493,P04035,Q9H2M9,P04439,Q96HY... | Localization | GO Cellular component | msigdb_gocc | 537,6,7,13,16,19,22,23,29,30,31,35,59,62,65,67,68,75,81,85,84,89,91,98,100,103,108,105,115,127,121,133,136,139,150,153,168,175,186,184,199,195,194,209,202,223,222,217,211,213,212,235,251,250,270,259,292,286,278,283,309,328,339,337,336,322,327,319,326,361,348,371,366,410,411,384,393,427,423,419,416,459,454,456,467,462,4... | 470,1061,1877,1219,2925,211,100,2164,471,2892,2990,319,384,928,1972,2330,212,550,3131,851,996,2332,2671,139,2482,1460,322,2607,1716,592,2672,29,1067,2552,2861,796,1540,2774,68,105,507,856,1226,2612,2171,2554,1979,2775,1981,1889,1631,799,1228,213,698,859,153,2733,645,2968,194,259,202,860,1157,3057,195,931,1382,1898,2777... | 0.603398739242378,0.1847155783283068,-0.21844879395768765,0.10581674080916348,-0.9072118013025617,1.033866168077631,1.7008953568023113,-0.34356283749264765,0.603398739242378,-0.8626367719544891,-1.0421318380239888,0.8217925949426864,0.7134182805889118,0.26273353937402294,-0.25994298419798034,-0.4280193129695504,1.03386... | 3,193 |
Nuclear outer membrane endoplasmic reticulum membrane network | 75 | 285 | 4.548141 | 0.000005 | Q9NQC3,Q9H3N1,Q9NZ08,Q14108,P30519,Q9UM00,Q9Y4P3,O43731,Q99720,P43307,Q9BQE5,P24390,Q5BJF2,Q15800,O95864,Q9HBH5,Q13190,Q92604,O60725,Q03518,Q06136,P57088,P09601,Q86XL3,Q9UBV2,Q86YN1,Q53GQ0,P61009,Q9BRR6,P46977,Q9Y282,Q9BUN8,Q5J8M3,Q9HD20,Q9BZF3,Q10471,Q96G23,Q8TCJ2,O75844,Q9P2W9,P06493,P04035,Q96RL7,Q9H2M9,Q15392,O4385... | Localization | GO Cellular component | msigdb_gocc | 537,270,133,6,7,410,411,139,13,16,19,22,23,150,153,292,393,286,29,30,31,278,35,283,168,309,427,423,175,419,186,184,454,59,62,328,65,199,68,467,195,194,462,209,75,322,319,202,81,361,85,84,223,496,222,91,217,213,103,235,348,366,477,470,108,471,105,480,115,251,250,371,483,127,121 | 470,1061,1877,1219,2925,2164,471,2990,319,928,1972,2548,2330,3131,851,996,2332,2671,139,322,2607,1716,2672,29,1067,796,1540,68,105,507,856,1226,2612,2171,2554,1979,2775,1889,799,1228,213,698,859,153,2733,645,2968,194,202,860,1157,195,2995,931,1382,1898,35,1077,2259,935,1805,1637,2622,1388,2624,22,1164,2495,937,2827,163... | 0.603398739242378,0.1847155783283068,-0.21844879395768765,0.10581674080916348,-0.9072118013025617,-0.34356283749264765,0.603398739242378,-1.0421318380239888,0.8217925949426864,0.26273353937402294,-0.25994298419798034,-0.5562590173955732,-0.4280193129695504,-1.5046126429246862,0.30141428148632216,0.22383486656935098,-0.... | 3,193 |
Transmembrane transport | 35 | 211 | 4.452613 | 0.000008 | Q9UHG3,Q96ES6,O60830,Q9Y6M7,O43772,Q03518,Q8IXU6,P21796,Q99797,Q9NS69,Q9UDW1,P51798,Q9H2D1,Q8WTV0,Q99595,O95831,Q9HD20,Q70HW3,O75844,P45880,Q9C0H2,Q13423,Q8TDW0,Q15629,Q7L0J3,Q9HC07,Q9Y619,Q7KZN9,P53985,Q12959,Q9BQT8,Q9UBX3,P42858,O75964,P08183 | Processes and pathways | GO Biological process | msigdb_gobp | 4,5,8,25,26,30,36,37,166,41,42,170,50,51,56,58,59,64,68,69,76,77,81,85,88,89,92,95,102,103,109,110,107,106,120 | 636,1879,2950,1790,2991,321,853,997,26,638,2607,2673,8,363,641,2333,1068,1376,797,1887,243,68,507,1223,106,1309,555,999,58,800,699,259,2255,3167,3057,1074,1893,2073,2488,2677,2617,801,2929,120,1464,1159,3111,2178,2618,2778,1465,261,1161,647,388,1805,2491,1467,2181,2082,2182,2739,2346,37,650,1163,2682,936,3096,743,1165,... | 0.4540235095844826,-0.21844879395768765,-0.9519864382224174,-0.17716618352898394,-1.0421318380239888,0.8217925949426864,0.30141428148632216,0.22383486656935098,3.481516904512842,0.4540235095844826,-0.5994172002524207,-0.6427799465527326,5.710127312386168,0.7497224929294436,0.4540235095844826,-0.4280193129695504,0.18471... | 3,193 |
Transporters | 85 | 359 | 4.430086 | 0.000009 | Q14108,Q99720,P24390,Q5BJF2,Q9Y6M7,O43772,Q03518,Q8IXU6,O60637,Q9H2D1,Q8WTV0,Q5VW38,Q9HD20,Q70HW3,Q9NR77,Q969E2,O75844,P45880,Q9C0H2,P07602,Q8TDW0,Q15629,Q9HC07,Q9Y619,O95782,P53985,Q12959,Q9BQT8,Q9UBX3,Q13555,Q9Y6C9,Q9H061,P08183,Q9BTX1,Q9BRK5,Q92544,P81605,Q9NZJ7,Q9UBV2,P51798,Q8NE00,P46934,Q6N075,Q9BUN8,P14635,Q8TCJ... | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 6,13,22,23,25,26,30,36,39,50,51,52,59,64,66,67,68,69,76,79,81,85,89,92,94,102,103,109,110,108,128,126,120,132,147,146,149,167,168,170,173,169,172,184,179,199,195,194,202,200,225,212,252,243,270,258,289,278,307,297,330,325,354,382,373,366,363,410,388,384,393,419,416,413,457,459,454,462,446,441,496,492,502,488,470 | 470,2249,689,2950,1970,2858,2925,1065,1144,1145,787,2991,200,384,2548,2481,212,550,441,3131,1066,472,2409,694,2482,26,638,2607,1461,1305,794,297,854,39,2411,551,413,1150,363,641,796,2484,797,1629,2609,243,68,507,1798,856,1225,258,2171,2730,1979,2821,555,1889,1155,2614,2172,94,644,800,699,2615,1890,194,1983,2928,202,189... | 0.603398739242378,-0.3856868930458746,0.41618190889414125,-0.9519864382224174,-0.25994298419798034,-0.8182620339173361,-0.9072118013025617,0.1847155783283068,0.1453758906367192,0.1453758906367192,0.33988043265628903,-1.0421318380239888,1.0686319460690494,0.7134182805889118,-0.5562590173955732,-0.5133061398194652,1.0338... | 3,193 |
Transport | 102 | 483 | 4.325108 | 0.000015 | Q96ES6,O60830,Q96CU9,A6NIH7,Q99720,Q13432,Q13505,Q9BQE5,P24390,Q9Y6M7,O43772,Q03518,Q8IXU6,P21796,Q9NS69,Q9UDW1,O43676,Q9H2D1,Q99595,Q9HD20,Q9BZF3,Q70HW3,Q969E2,P45880,Q9Y487,Q9C0H2,Q8TDW0,Q15629,O43169,Q7L0J3,Q9Y619,O43396,O95782,O75306,O00461,P53985,Q9BQT8,Q9UBX3,O75964,Q9Y6C9,P08183,Q9BTX1,Q12893,O43731,O95864,Q9NZJ... | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 5,8,9,11,13,14,15,19,22,25,26,30,36,37,41,42,46,50,56,59,62,64,67,69,73,76,81,85,87,88,92,93,94,97,100,102,109,110,106,128,120,132,136,139,153,167,170,172,186,184,189,197,198,213,212,233,231,252,243,246,270,289,316,304,302,339,327,319,321,325,361,357,354,382,380,365,363,362,410,384,393,438,425,426,417,416,413,457,456,4... | 439,470,1877,11,2249,689,1879,1301,3175,2950,1970,2328,2546,100,1065,1790,1144,787,2990,927,319,384,321,362,549,2548,2330,2481,212,550,1066,789,472,87,1714,2332,93,1793,2409,853,2993,46,694,997,139,2482,26,638,2069,1305,854,592,1375,2411,2169,2552,413,1150,8,363,641,1720,3019,1068,97,998,797,1540,1069,1629,1888,2609,16... | 0.640258997817798,0.603398739242378,-0.21844879395768765,5.130323467956688,-0.3856868930458746,0.41618190889414125,-0.21844879395768765,0.06603905308700285,-2.537457890708034,-0.9519864382224174,-0.25994298419798034,-0.4280193129695504,-0.5562590173955732,1.7008953568023113,0.1847155783283068,-0.17716618352898394,0.145... | 3,193 |
Mitochondrial envelope | 105 | 305 | 4.038474 | 0.000054 | Q567V2,Q9NVH0,Q9NZ45,O60830,Q96CU9,Q13505,O76031,O43772,Q13057,P09601,Q16611,P21796,Q9NS69,Q8IWA4,Q9UDW1,P14406,O43676,Q9H2D1,P30536,Q99595,O95831,Q70HW3,O95202,O95168,P45880,Q13423,Q96DV4,Q9BRJ2,Q9BSK2,O43169,Q9BYC9,Q9H2W6,Q9Y619,Q9NQG6,Q7KZN9,O75306,Q9BQT8,Q9UBX3,Q9UDX5,O75964,P78537,Q9Y6C9,Q9H061,Q96AY3,Q9GZY8,Q9Y2R... | Localization | GO Cellular component | msigdb_gocc | 2,539,542,8,9,15,508,26,515,35,571,37,41,574,42,44,46,50,53,56,58,64,555,554,69,77,621,622,623,87,625,627,92,629,95,97,109,110,111,106,604,128,126,672,137,138,135,141,684,687,148,661,648,151,640,641,642,645,647,637,650,167,659,663,185,723,724,714,700,712,692,200,698,231,243,264,263,313,299,305,304,335,331,330,321,325,3... | 637,3175,1219,2925,1790,2771,2329,200,321,362,692,1792,87,2671,853,46,26,640,1461,1716,8,641,1975,1068,97,1376,998,1069,1887,1888,473,243,2335,1223,106,508,1309,2821,554,1379,555,642,698,859,58,800,645,699,1074,2488,2734,1159,1544,1633,35,1988,2178,2618,1724,1161,647,2970,388,44,2868,648,299,1386,1637,1806,2561,2082,37... | 0.4540235095844826,-2.537457890708034,0.10581674080916348,-0.9072118013025617,-0.17716618352898394,-0.7301162059779877,-0.4280193129695504,1.0686319460690494,0.8217925949426864,0.7497224929294436,0.41618190889414125,-0.17716618352898394,1.8277698868878607,-0.6427799465527326,0.30141428148632216,2.6081164823979903,3.481... | 3,193 |
Ion transmembrane transporter activity | 25 | 99 | 3.734374 | 0.000188 | Q96ES6,Q9Y6M7,O43772,P21796,Q9UDW1,P51798,Q9H2D1,Q6N075,Q9HD20,Q70HW3,P45880,Q9Y487,Q9C0H2,Q13423,Q8TDW0,Q9HC07,Q9Y619,Q7KZN9,P53985,Q9BQT8,Q9UBX3,O75964,Q93050,O75746,Q14728 | Functions | GO Molecular function | msigdb_gomf | 5,25,26,37,42,170,50,172,59,64,69,73,76,77,81,89,92,95,102,109,110,106,252,243,246 | 2950,2991,694,26,638,243,1223,106,555,699,2255,3167,1074,2488,2677,2929,1464,1159,3111,2178,2778,1161,647,388,1805,2181,2082,2182,2739,37,1163,2682,1083,1811,2000,2745,2630,1733,69,808,2354,3171,170,325,102,877,1170,1562,1479,2874,2959,1655,1657,952,77,246,1929,884,1580,172,2517,1187,488,667,64,95,1683,354,970,81,2711,... | -0.9519864382224174,-1.0421318380239888,0.41618190889414125,3.481516904512842,0.4540235095844826,0.9638462735845957,0.10581674080916348,1.6044026869650967,0.529103559661836,0.41618190889414125,-0.3856868930458746,-2.1841159131798,0.1847155783283068,-0.5133061398194652,-0.6427799465527326,-0.9072118013025617,-0.01416830... | 3,193 |
Mitochondrial protein containing complex | 43 | 145 | 3.70386 | 0.000212 | Q567V2,O60830,Q96CU9,Q9NYK5,Q6UXV4,Q13505,P13073,O76031,P53597,P15954,O95299,Q96A35,P12236,P21796,Q9Y6M9,Q9NS69,Q8IWA4,Q9UDW1,P14406,Q96RQ3,O43676,Q16795,P22695,Q9P0M9,O00330,Q99595,Q15388,O95168,O14925,Q96DV4,Q9BRJ2,Q9BYC9,Q9H2W6,Q6P1L8,Q14197,O75306,Q5T653,Q8N4H5,P21953,O75964,P54098,P82930,O14949 | Localization | GO Cellular component | msigdb_gocc | 2,8,9,409,141,15,388,508,511,648,642,431,647,37,438,41,574,42,44,578,46,426,417,185,412,56,304,554,321,621,622,625,627,353,351,97,486,231,595,106,114,368,362 | 3175,412,1369,1790,321,362,1883,46,1537,8,1068,97,998,1069,1888,1223,106,508,1309,554,1379,642,800,699,1074,2488,1897,1159,1544,1804,1988,1990,2178,1992,1161,647,388,44,2868,648,2561,2082,37,1315,595,417,1163,2682,2625,1165,745,1083,2089,2000,2831,1084,808,2354,1087,2091,1243,943,944,751,2635,511,114,1477,1170,1562,201... | -2.537457890708034,0.6769313036646232,0.026043738945028046,-0.17716618352898394,0.8217925949426864,0.7497224929294436,-0.21844879395768765,2.6081164823979903,-0.05459618476215373,5.710127312386168,0.1847155783283068,1.7328021609675641,0.22383486656935098,0.1847155783283068,-0.21844879395768765,0.10581674080916348,1.604... | 3,193 |
Mitochondria | 115 | 404 | 3.697443 | 0.000218 | Q9NUJ1,Q9NVH0,Q9NZ45,O60830,Q96CU9,Q13505,Q8WVV9,Q8TC07,O76031,P53597,O43772,Q9NS69,Q8IWA4,Q96RQ3,Q9H2D1,Q16740,Q9H019,Q99595,O95831,Q8TAE8,Q70HW3,O95168,O95202,P28070,P45880,Q13423,P13674,Q16880,Q969Z0,Q96DV4,Q9BYC9,Q9H2W6,Q9H7Z7,Q9NQG6,Q7KZN9,O75306,Q9UBX3,Q9UDX5,P21953,O75964,P36957,P54098,P60903,Q9Y6C9,Q96AY3,Q1512... | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 0,539,542,8,9,15,526,525,508,511,26,41,574,578,50,49,581,56,58,63,64,554,555,558,69,77,80,86,620,621,625,627,628,629,95,97,110,111,595,106,597,114,602,128,672,131,137,138,135,141,687,144,148,664,661,151,640,641,642,158,647,637,649,166,650,182,224,214,231,242,263,290,294,285,280,308,306,299,305,304,335,331,330,320,321,3... | 637,3175,412,1369,1790,320,321,362,1883,2817,2550,789,3153,2671,853,26,640,1537,1461,1716,1374,8,641,1975,97,1376,1977,1069,1887,1888,1306,473,242,1072,1223,106,508,1309,2926,2821,554,1379,555,642,58,2555,800,1380,1311,3073,2414,1891,1074,342,2488,1381,1897,1159,2930,1804,1988,1990,2178,2618,1992,1724,344,1161,647,388,... | 0.4540235095844826,-2.537457890708034,0.6769313036646232,0.026043738945028046,-0.17716618352898394,0.8217925949426864,0.8217925949426864,0.7497224929294436,-0.21844879395768765,-0.7740882787487618,-0.5562590173955732,0.33988043265628903,-1.8884072030304302,-0.6427799465527326,0.30141428148632216,3.481516904512842,0.454... | 3,193 |
Intrinsic component of organelle membrane | 42 | 124 | 3.639278 | 0.000273 | Q9BTV4,Q9UM00,Q9GZY8,Q9Y2R0,O60830,Q9Y4P3,Q6UXV4,O94901,Q13505,Q6ZRP7,Q96K12,P57088,Q03518,Q86XL3,Q15286,Q86YN1,Q9Y282,Q9BUN8,Q99595,P17152,O43505,Q5J8M3,P42892,Q15388,Q10471,O75844,Q15070,P57105,O15258,O14925,P04439,Q9UH99,Q15629,Q99442,Q8NC56,Q7L0J3,Q92643,Q14739,O15126,Q6P4A7,A0FGR8,Q5SNT2 | Localization | GO Cellular component | msigdb_gocc | 402,410,137,138,8,411,141,258,15,396,287,278,30,283,425,309,186,184,56,299,178,454,188,304,328,68,330,446,441,321,202,225,85,496,221,88,222,91,212,488,470,118 | 470,636,471,321,2481,212,441,178,638,640,592,8,1069,68,2335,856,1309,258,2821,799,800,2968,202,1077,1161,2418,299,2181,2081,2495,937,1639,2831,188,2633,749,1004,2435,2095,278,446,1912,2874,2959,1655,30,328,1012,15,1573,91,2283,330,1931,425,304,85,663,571,3164,1330,1414,454,118,1841,488,141,396,88,1505,283,2961,309,574,... | 0.603398739242378,0.4540235095844826,0.603398739242378,0.8217925949426864,-0.5133061398194652,1.033866168077631,0.640258997817798,1.1719772075302926,0.4540235095844826,0.4540235095844826,0.49166307589473773,5.710127312386168,0.1847155783283068,2.1365684786427637,-0.4280193129695504,0.30141428148632216,0.066039053087002... | 3,193 |
Amide binding | 26 | 100 | 3.583524 | 0.000339 | Q9NZ08,O43731,O00154,P55786,P49748,P24390,Q03518,Q9UIQ6,P45877,P21796,Q9NZJ7,Q9NQX7,Q8WTV0,P49327,P42892,Q15388,P45880,Q15392,P07602,P04439,P35610,P11498,P05165,Q9Y680,Q5SW96,P50747 | Functions | GO Molecular function | msigdb_gomf | 133,139,256,18,148,22,30,32,277,37,167,45,51,54,188,304,69,75,79,202,84,344,342,101,229,244 | 256,1969,1219,1970,1144,787,2329,2166,1973,139,2411,1306,1309,1311,2968,202,342,79,1896,2777,1077,344,2079,2623,37,1080,1729,22,1164,2495,1165,346,84,1731,2429,2690,1084,1733,188,277,69,3079,54,148,1241,1242,244,1560,2505,1561,18,2439,2874,2834,2098,2791,2101,1827,3004,30,2277,2199,1490,2699,1257,2201,2577,2373,2450,30... | 0.9285879028743135,-0.25994298419798034,0.10581674080916348,-0.25994298419798034,0.1453758906367192,0.33988043265628903,-0.4280193129695504,-0.34356283749264765,-0.25994298419798034,1.4078086405789536,-0.47055931834629494,0.06603905308700285,0.06603905308700285,0.06603905308700285,-0.996960006644522,1.0686319460690494,... | 3,193 |
Ion transport | 31 | 200 | 3.5197 | 0.000432 | Q9UHG3,Q96ES6,Q9Y6M7,O43772,P21796,Q9NZJ7,Q9UDW1,P51798,Q9H2D1,P46934,P30536,Q9HD20,Q70HW3,O75844,P45880,Q9C0H2,Q13423,P07602,Q8TDW0,Q7L0J3,Q9HC07,Q9Y619,Q7KZN9,P53985,Q12959,Q9BQT8,Q9UBX3,Q13555,P42858,O75964,P08183 | Processes and pathways | GO Biological process | msigdb_gobp | 4,5,25,26,37,167,42,170,50,169,53,59,64,68,69,76,77,79,81,88,89,92,95,102,103,109,110,108,107,106,120 | 689,2950,2925,1790,2991,2547,1882,589,694,997,26,638,2607,2673,363,641,2333,1068,1376,1887,243,68,507,1223,106,856,555,999,800,699,1890,2928,1632,2255,3167,3057,1074,1893,2073,2488,2677,2617,79,2929,120,1464,1159,3111,2178,2778,1991,261,1161,647,388,1726,2680,1805,2491,1467,2181,2082,2182,2739,2346,37,1163,596,2682,936... | 0.41618190889414125,-0.9519864382224174,-0.9072118013025617,-0.17716618352898394,-1.0421318380239888,-0.5562590173955732,-0.21844879395768765,0.49166307589473773,0.41618190889414125,0.22383486656935098,3.481516904512842,0.4540235095844826,-0.5994172002524207,-0.6427799465527326,0.7497224929294436,0.4540235095844826,-0.... | 3,193 |
Ion transmembrane transport | 25 | 154 | 3.365468 | 0.000764 | Q9UHG3,Q96ES6,Q9Y6M7,O43772,P21796,Q9UDW1,P51798,Q9H2D1,Q9HD20,Q70HW3,O75844,P45880,Q9C0H2,Q13423,Q8TDW0,Q9HC07,Q9Y619,Q7KZN9,P53985,Q12959,Q9BQT8,Q9UBX3,P42858,O75964,P08183 | Processes and pathways | GO Biological process | msigdb_gobp | 4,5,25,26,37,42,170,50,59,64,68,69,76,77,81,89,92,95,102,103,109,110,107,106,120 | 2950,1790,2991,997,26,638,2607,2673,363,641,2333,1068,1376,1887,243,68,507,1223,106,555,999,699,2255,3167,3057,1074,1893,2488,2677,2617,2929,120,1464,1159,3111,2178,261,1161,647,388,1805,2491,1467,2181,2082,2182,2739,2346,37,1163,2682,936,3096,1165,2998,1083,1811,2000,2745,2630,1733,107,69,169,2434,808,2354,1091,3171,1... | -0.9519864382224174,-0.17716618352898394,-1.0421318380239888,0.22383486656935098,3.481516904512842,0.4540235095844826,-0.5994172002524207,-0.6427799465527326,0.7497224929294436,0.4540235095844826,-0.4280193129695504,0.1847155783283068,0.026043738945028046,-0.21844879395768765,0.9638462735845957,2.1365684786427637,0.566... | 3,193 |
Transporter | 37 | 182 | 3.345881 | 0.00082 | Q96ES6,O43731,Q92544,Q9BQE5,Q99808,P24390,Q9Y6M7,O43772,Q9HD45,Q03518,Q8IXU6,Q9NZJ7,Q9H2D1,Q6N075,Q15388,Q96FZ7,Q70HW3,Q15070,Q9Y487,P56377,O14653,P53007,Q9Y3A6,Q7L0J3,Q9HC07,Q9BTX7,Q8TAD4,Q9Y619,O95487,Q93050,P53985,Q9BQT8,Q96AX1,Q9UBX3,Q9Y6C9,O75746,P08183 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 5,139,146,19,289,22,25,26,156,30,36,167,50,172,304,189,64,330,73,327,319,325,361,88,89,357,354,92,213,252,102,109,233,110,128,243,120 | 689,1879,1301,1065,1144,787,2990,927,319,341,139,3155,26,638,592,1375,2411,2169,2552,641,1629,243,1223,1979,555,1981,1889,1228,213,1073,800,2255,3167,1074,2488,120,1464,2777,2778,2737,1161,647,2418,1805,2780,2181,2182,2739,22,1163,2682,743,1235,1811,1472,2000,2351,2630,1733,1906,2270,874,1090,2435,3085,1560,2505,325,22... | 0.41618190889414125,-0.21844879395768765,0.06603905308700285,0.1847155783283068,0.1453758906367192,0.33988043265628903,-1.0421318380239888,0.26273353937402294,0.8217925949426864,0.7858464474140958,1.4078086405789536,-1.8884072030304302,3.481516904512842,0.4540235095844826,0.49166307589473773,0.026043738945028046,-0.470... | 3,193 |
Mitochondrion organization | 35 | 189 | 3.343803 | 0.000826 | Q9GZY8,Q9Y2R0,O60830,Q96CU9,O95429,Q6UXV4,P04062,Q13505,P55786,Q9GZT3,Q5JRX3,P21796,Q99797,Q9BUK6,Q9NS69,P14406,O43676,P30536,Q99595,P17152,O95831,Q69YU5,Q15388,O75153,P45880,Q15070,O14925,Q16706,O75306,Q5T9A4,Q8N4H5,Q9UDX5,P42858,Q9Y6C9,Q9H061 | Processes and pathways | GO Biological process | msigdb_gobp | 137,138,8,9,140,141,259,15,18,290,158,37,166,313,41,44,46,53,56,299,58,305,304,60,69,330,321,98,97,372,231,111,107,128,126 | 1709,637,3056,1301,3175,2925,2606,321,1971,2671,853,46,640,1461,8,60,1628,1068,97,1376,1069,1887,1888,1541,2335,1309,2821,554,555,642,2927,140,2863,58,800,2175,1890,259,3073,1891,1074,2415,1633,1545,2618,2620,1161,44,299,475,37,3096,2625,2085,1165,2497,53,2743,2089,2427,1642,2831,2500,107,69,808,2934,1396,874,3144,1818... | -0.13609598281271182,0.4540235095844826,-1.178830334389834,0.06603905308700285,-2.537457890708034,-0.9072118013025617,-0.5994172002524207,0.8217925949426864,-0.25994298419798034,-0.6427799465527326,0.30141428148632216,2.6081164823979903,0.4540235095844826,-0.014168302611951702,5.710127312386168,2.405017553399409,-0.095... | 3,193 |
Tdark | 95 | 333 | 3.209411 | 0.00133 | Q9Y3B3,Q96ES6,O60830,Q96CN7,Q969T7,Q86YQ8,Q86U38,Q7L8L6,Q5TFE4,Q8IXU6,Q9BWJ5,Q8IYS2,P14406,Q5VW38,Q9HD20,Q9NR77,Q969E2,Q8TDW0,Q5JSZ5,Q15629,O75964,Q5SNT2,Q9UKR5,Q96DM3,O43731,Q9Y2W6,O94915,Q9HD45,Q9Y305,Q8N128,Q5C9Z4,Q8NE00,Q6N075,Q9P0M9,Q9BV19,Q9H9Y2,Q9Y6J9,Q8IXT5,Q9NXF1,Q8NC56,Q7Z4H3,O15126,Q9H1I8,Q9BQ61,Q8N4H5,Q9BWH... | Drugs and Diseases | Pharos IDG Category | pharos_protein_category | 547,5,8,528,28,523,522,520,519,36,579,575,44,52,59,66,67,81,82,85,106,118,127,123,139,143,152,156,160,159,164,173,172,185,190,192,193,207,224,221,219,212,236,234,231,254,250,245,273,288,293,285,284,309,312,307,316,306,299,305,338,335,334,359,357,353,352,373,368,399,400,401,403,409,397,395,386,428,430,431,435,423,454,46... | 439,2605,785,2162,1709,786,636,995,212,440,3153,853,139,1304,1974,2070,8,1719,741,1308,106,152,386,3162,2865,3111,44,648,299,1638,2691,3098,1736,2190,809,2438,423,2442,950,752,2100,1407,659,368,712,1251,245,753,814,1658,1659,3116,2025,481,352,818,2283,1577,395,85,1937,2843,1839,2029,453,2452,164,454,82,1668,1416,118,61... | 0.640258997817798,-0.5994172002524207,0.33988043265628903,-0.34356283749264765,-0.13609598281271182,0.33988043265628903,0.4540235095844826,0.22383486656935098,1.033866168077631,0.640258997817798,-1.8884072030304302,0.30141428148632216,1.4078086405789536,0.06603905308700285,-0.25994298419798034,-0.30164793499149467,5.71... | 3,193 |
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