term
stringlengths
2
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overlap
int64
6
281
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int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Abnormal nerve conduction velocity
10
44
3.022928
0.002503
Q9NR77,Q99720,P07602,O95831,P02545,Q71SY5,O43681,Q9GZY8,P07196,Q00796
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,2,69,47,265,144,118,130,125,156
746,118,1776,791,47,265,125,69,1878,1222,1713,2711,2662,890,1467,1800,1155,2156,2238,2242,2349,3408,3471,156,3328,2087,2091,627,2946,144,464,300,859,2734,1053,2,130,3533,32,1064,3243,1521,1767,693
0.4117022638315761,1.7982903969638317,-0.06576592628969985,0.3803099800917596,3.0119856905575273,1.0578712931665288,1.7400910153055076,2.427791890653298,-0.098122333905974,0.15884550726049723,-0.03347806686168351,-0.42560918711049844,-0.3925286203228279,0.31734400267200297,0.06298071889501843,-0.06576592628969985,0.19067127264620573,-0.19560956934146895,-0.22824695247054547,-0.22824695247054547,-0.2609563355332265,-1.0350054838275398,-1.174345720866778,1.5350292358486646,-0.8971691305719629,-0.16304347134508207,-0.16304347134508207,0.5055225334229401,-0.5587053640309138,1.5938382520831849,0.6916031594494587,0.9973494401983068,0.34885740302862467,-0.42560918711049844,0.25413257026133235,8.21990109917503,1.7109272480905777,-1.3507131280591325,3.6085359292973544,0.25413257026133235,-0.7947358122572576,0.06298071889501843,-0.03347806686168351,0.47430803058067816
3,643
Abnormal metatarsal morphology
12
31
3.000974
0.002691
Q8WVQ1,Q96L58,Q7RTS9,Q15392,O43505,Q03252,Q9Y448,Q9H9S5,P08236,Q9Y366,Q9UBM7,O96028
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
423,303,11,45,205,207,348,347,455,290,289,87
2502,205,2412,3288,1372,87,455,1377,2145,2337,3197,592,1802,207,1396,1562,900,45,1038,11,480,423,303,2020,2390,347,1429,289,2041,290,348
-0.3265940252928932,1.2979715997804608,-0.29373844618932715,-0.8629365633590367,0.09500082791205905,2.11542427763213,0.6916031594494587,0.09500082791205905,-0.19560956934146895,-0.2609563355332265,-0.7607655898218467,0.5366787829519797,-0.06576592628969985,1.2979715997804608,0.09500082791205905,0.030894617027511038,0.31734400267200297,3.1215736355280526,0.25413257026133235,5.543953911878619,0.6607309570482511,0.7531817696547146,0.9973494401983068,-0.13054795621506413,-0.2609563355332265,0.9061816816409076,0.09500082791205905,1.027635769907882,-0.13054795621506413,1.027635769907882,0.9061816816409076
3,643
Signal transduction by p53 class mediator
8
50
2.989006
0.002799
P46379,Q8N2F6,Q9UNS2,Q01664,Q7LG56,P14174,Q13573,O75844
Processes and pathways
GO Biological process
msigdb_gobp
3,467,106,327,464,15,88,248
2323,999,2211,1366,933,1864,1217,1615,248,1616,2651,1288,15,1459,592,1086,1883,2933,3,1466,1808,1724,896,1809,1985,2249,2078,1558,2252,327,88,1817,2361,2600,464,467,481,1923,1925,1187,1928,730,2548,3334,2473,2030,1685,784,1595,106
-0.2609563355332265,0.25413257026133235,-0.22824695247054547,0.09500082791205905,0.2857692407025649,-0.098122333905974,0.15884550726049723,-0.0012581004565036626,1.118191455601226,-0.0012581004565036626,-0.3925286203228279,0.12695555655645674,4.964849362308119,0.06298071889501843,0.5366787829519797,0.2224334357534765,-0.098122333905974,-0.5587053640309138,7.00443820279511,0.06298071889501843,-0.06576592628969985,-0.03347806686168351,0.31734400267200297,-0.06576592628969985,-0.13054795621506413,-0.22824695247054547,-0.16304347134508207,0.030894617027511038,-0.22824695247054547,0.9366227945511973,2.11542427763213,-0.06576592628969985,-0.2609563355332265,-0.3595238272390506,0.6916031594494587,0.6916031594494587,0.6607309570482511,-0.098122333905974,-0.098122333905974,0.19067127264620573,-0.098122333905974,0.44303477605405855,-0.3265940252928932,-0.8971691305719629,-0.29373844618932715,-0.13054795621506413,-0.0012581004565036626,0.4117022638315761,0.030894617027511038,1.943054324684516
3,643
Organic anion transport
22
56
2.947082
0.003208
Q86VD7,Q14728,Q01650,P14174,Q7L0J3,Q9HC21,Q9Y619,P11166,O00400,O95563,Q9UBX3,P80404,Q9BQT8,Q8TB61,P53985,Q15758,P30825,P55011,Q9H2D1,P07602,P41440,Q9Y6M7
Processes and pathways
GO Biological process
msigdb_gobp
256,624,143,15,17,553,693,279,646,152,306,413,577,573,44,662,54,440,733,69,90,361
646,2793,2049,1003,2754,2219,1450,3068,152,2508,1962,1873,3218,69,704,3219,279,2331,1145,15,1622,54,2342,90,2073,44,440,413,143,2771,1395,624,1317,765,662,2274,2366,3456,17,256,1177,573,2829,2906,2907,2292,577,733,1057,553,1432,1064,306,924,693,361
0.47430803058067816,-0.4920008457387619,-0.16304347134508207,0.25413257026133235,-0.4587663248239629,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,-0.3265940252928932,-0.13054795621506413,-0.098122333905974,-0.7947358122572576,2.427791890653298,0.44303477605405855,-0.7947358122572576,1.027635769907882,-0.2609563355332265,0.19067127264620573,4.964849362308119,-0.0012581004565036626,2.707887319665007,-0.2609563355332265,2.058127752852981,-0.16304347134508207,3.1215736355280526,0.7224199472328477,0.7531817696547146,1.5938382520831849,-0.4587663248239629,0.09500082791205905,0.5055225334229401,0.12695555655645674,0.4117022638315761,0.47430803058067816,-0.22824695247054547,-0.2609563355332265,-1.1393655482262741,4.734981990697083,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.4920008457387619,-0.525313577596298,-0.525313577596298,-0.22824695247054547,0.5677772700633923,0.44303477605405855,0.25413257026133235,0.5988184783374502,0.09500082791205905,0.25413257026133235,0.9973494401983068,0.31734400267200297,0.47430803058067816,0.8756881681175116
3,643
Lytic vacuole organization
13
32
2.943006
0.00325
Q14108,P50897,Q9HC07,O75787,Q96ED9,P10253,O14773,P54802,Q8NHS3,O75503,P11117,Q9NWW5,Q14457
Processes and pathways
GO Biological process
msigdb_gobp
255,72,405,296,179,266,391,147,52,24,236,251,189
1952,391,24,296,703,3538,266,236,1086,72,2156,147,2075,801,255,189,1036,2001,771,1914,52,2180,179,2624,448,405,3337,251,2633,643,1690,1437
-0.13054795621506413,0.7838890695289682,4.11230346222967,0.9973494401983068,0.44303477605405855,-1.3862754857551036,1.0578712931665288,1.1482768495977804,0.2224334357534765,2.399583395405736,-0.19560956934146895,1.5644560394229112,-0.16304347134508207,0.3803099800917596,1.08805639508316,1.387215394486587,0.25413257026133235,-0.13054795621506413,0.4117022638315761,-0.098122333905974,2.818941470146897,-0.19560956934146895,1.446478167816503,-0.3595238272390506,0.7224199472328477,0.7838890695289682,-0.8971691305719629,1.118191455601226,-0.3595238272390506,0.5055225334229401,-0.0012581004565036626,0.09500082791205905
3,643
Vacuole
68
249
2.942146
0.003259
Q14108,P42785,P78371,O15118,Q8WTV0,Q9HD42,Q9HC07,P30511,Q01650,P10253,O14773,Q9UM22,P54802,O75503,Q8TCT8,Q8NCC3,P06280,P16278,Q9UHG3,P19474,P20645,Q9UIQ6,Q9Y487,Q07065,O75787,P15586,O14678,Q9BXS4,Q8NHS3,P42892,P00813,Q8NHP8,Q92542,P10619,Q14457,P33176,O00754,P07602,Q8IV08,P50897,P55735,Q8IY95,Q96RU3,Q9UMR5,P51790,Q93050,P08236,P51798,P41440,Q9NRA0,P04066,Q15012,O00584,P61916,P51809,P17655,O15260,Q15165,Q86YV9,Q99523,Q9BTY2,P15291,P11117,Q969Q5,O43681,O75955,Q9NQX7,Q9NUN5
Localization
GO Cellular component
msigdb_gocc
255,4,378,252,8,276,405,138,143,266,391,22,147,24,158,28,153,155,430,36,37,42,43,173,296,410,176,50,52,53,56,58,317,59,189,312,435,69,73,72,201,466,204,77,459,82,455,460,90,227,228,353,103,351,476,473,108,109,479,114,115,112,236,482,118,249,122,123
1952,2322,103,435,2792,176,391,1774,252,108,586,3187,2963,118,2860,1138,588,2700,1078,3361,24,296,249,2798,1456,2507,2328,2704,56,3617,703,228,3104,153,1013,3191,3151,1701,69,3538,1789,3106,704,455,1457,2057,1702,2143,266,59,3219,236,2144,1964,1082,2332,112,410,155,473,2869,36,37,3294,2061,3422,2927,563,3073,2658,3197,2580,3324,138,3407,2873,312,707,1624,847,3578,2661,3200,90,1086,4,53,1977,1628,2432,2935,1020,72,2237,3265,1300,2156,1552,459,3607,460,476,1805,1632,2348,1806,147,2349,201,2768,2717,1723,2586,2075,1023,2587,351,3571,2251,1636,2161,378,952,1560,2813,143,2257,622,2938,173,2772,1160,1727,1398,898,1238,3473,1030,255,2087,189,3301,1036,353,963,109,854,2532,541,1320,3390,666,2001,3126,1911,479,73,1177,466,1914,1663,28,1180,1916,58,52,3478,158,8,3356,2099,317,1417,82,482,2380,2180,1835,1050,679,574,2624,1675,204,1507,114,2111,520,3234,864,3179,683,1929,115,3642,3002,50,1933,3237,1423,3211,2115,3479,1349,1936,1350,2391,2693,2303,405,1844,276,1193,122,227,1195,123,2912,3337,2307,1850,2202,1064,739,1199,2633,1065,1944,430,2401,42,2041,22,1595,77,2043,2309,2127,2492,1690,1599,1436,3493,1437,43,1280,609,995,877
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3,643
Positive regulation of immune system process
34
129
2.917268
0.003531
P23246,P46379,Q9HCL2,P30511,P14174,Q01650,Q9NY93,P05067,Q06481,Q9BY67,P02786,Q7Z434,P30825,P00813,P23396,Q15046,Q15233,P12956,P04439,O96028,O15400,P78536,Q9NPF0,Q9BX67,Q9NRA0,P31749,Q9NUQ9,P51809,Q9NQT5,O95219,Q99538,Q9H2U1,P26583,P49770
Processes and pathways
GO Biological process
msigdb_gobp
375,3,5,138,15,143,429,29,39,304,409,420,54,56,437,566,567,83,590,87,586,216,492,488,227,592,102,476,638,235,520,522,616,618
1770,1952,1605,2792,2050,586,2215,2502,2860,2794,2796,1698,1616,235,2053,87,2757,56,1872,409,2508,590,29,2509,1789,1081,653,3256,1704,1082,83,1146,15,941,3629,942,1084,2427,1878,375,437,616,3322,2658,3197,138,54,592,2229,3297,1547,890,1548,3117,3,3440,618,3344,476,1632,3160,3118,1156,1390,216,143,1893,2938,1815,39,1310,623,1394,1395,1727,2526,1645,1479,2672,1818,1315,566,567,1037,2532,1404,3042,1246,1100,2535,969,420,2949,973,1111,2178,2015,2377,1923,2619,914,1339,2621,1261,1928,1506,3177,520,3235,919,488,304,522,3533,5,492,638,2394,2743,227,989,102,429,828,3245,3098,2308,2040,2788
-0.06576592628969985,-0.13054795621506413,-0.0012581004565036626,-0.4920008457387619,-0.16304347134508207,0.5366787829519797,-0.22824695247054547,-0.3265940252928932,-0.525313577596298,-0.4920008457387619,-0.4920008457387619,-0.03347806686168351,-0.0012581004565036626,1.1482768495977804,-0.16304347134508207,2.11542427763213,-0.4587663248239629,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,3.6353042018995785,-0.3265940252928932,-0.06576592628969985,0.2224334357534765,0.47430803058067816,-0.8287924672030076,-0.03347806686168351,0.2224334357534765,2.172563346869744,0.19067127264620573,4.964849362308119,0.2857692407025649,-2.997816021189173,0.2857692407025649,0.2224334357534765,-0.29373844618932715,-0.098122333905974,0.8145422833591529,0.7224199472328477,0.5055225334229401,-0.8971691305719629,-0.3925286203228279,-0.7607655898218467,1.623176179314646,2.707887319665007,0.5366787829519797,-0.22824695247054547,-0.8629365633590367,0.030894617027511038,0.31734400267200297,0.030894617027511038,-0.6930805097254553,7.00443820279511,-1.104482929673742,0.5055225334229401,-0.931491220478586,0.6607309570482511,-0.0012581004565036626,-0.726880811724572,-0.6930805097254553,0.19067127264620573,0.09500082791205905,1.2382387072449188,1.5938382520831849,-0.098122333905974,-0.5587053640309138,-0.06576592628969985,3.257840018273795,0.12695555655645674,0.5055225334229401,0.09500082791205905,0.09500082791205905,-0.03347806686168351,-0.3265940252928932,-0.0012581004565036626,0.06298071889501843,-0.3925286203228279,-0.06576592628969985,0.12695555655645674,0.5677772700633923,0.5677772700633923,0.25413257026133235,-0.3265940252928932,0.09500082791205905,-0.6257295573052645,0.15884550726049723,0.2224334357534765,-0.3265940252928932,0.2857692407025649,0.7531817696547146,-0.5587053640309138,0.2857692407025649,0.2224334357534765,-0.19560956934146895,-0.13054795621506413,-0.2609563355332265,-0.098122333905974,-0.3595238272390506,0.31734400267200297,0.12695555655645674,-0.3595238272390506,0.15884550726049723,-0.098122333905974,0.06298071889501843,-0.726880811724572,0.6298028841948623,-0.7947358122572576,0.31734400267200297,0.6607309570482511,0.9973494401983068,0.6298028841948623,-1.3507131280591325,6.233993929662534,0.6607309570482511,0.5055225334229401,-0.2609563355332265,-0.42560918711049844,1.2083001127798034,0.2857692407025649,1.9718833674139287,0.7531817696547146,0.3803099800917596,-0.7947358122572576,-0.6593637349435877,-0.22824695247054547,-0.13054795621506413,-0.4587663248239629
3,643
Endocytic vesicle
29
100
2.909599
0.003619
Q14108,Q4VCS5,Q8WTV0,P30511,O43493,Q5KU26,Q16625,P11717,P10321,P20645,Q06481,Q9Y487,P02786,Q9BZG1,Q14457,P33176,O00461,P51790,Q9Y4G8,Q93050,O43752,P61020,P04439,Q9H223,P51809,P08670,Q13555,Q969Q5,Q9NUN5
Localization
GO Cellular component
msigdb_gocc
255,512,8,138,142,396,541,154,532,37,39,43,409,448,189,312,70,459,81,82,454,596,590,490,476,104,105,482,123
2132,1207,70,1444,1774,586,1695,142,454,1213,2412,1449,2798,2328,3617,1872,409,590,1012,1789,104,1702,1703,532,887,1082,154,3591,2332,2513,2578,37,2658,3030,138,3520,312,1086,1155,3265,1300,2156,1552,2347,459,476,2348,1723,2805,596,1890,2075,2587,3077,2251,952,2257,1028,39,1727,2596,105,3348,255,1315,189,1036,2089,2269,902,1166,3124,2271,541,512,396,767,1655,970,1910,810,8,2015,82,482,1050,3234,448,3479,490,1937,123,3098,2041,1595,2127,43,81,1768,1204
-0.19560956934146895,0.15884550726049723,2.399583395405736,0.06298071889501843,-0.06576592628969985,0.5366787829519797,-0.03347806686168351,1.5938382520831849,0.6916031594494587,0.15884550726049723,-0.29373844618932715,0.06298071889501843,-0.4920008457387619,-0.2609563355332265,-2.342454069604444,-0.098122333905974,0.7531817696547146,0.5366787829519797,0.25413257026133235,-0.06576592628969985,1.943054324684516,-0.03347806686168351,-0.03347806686168351,0.5988184783374502,0.31734400267200297,0.2224334357534765,1.5350292358486646,-1.7470088834303552,-0.2609563355332265,-0.3265940252928932,-0.3595238272390506,3.284999162596966,-0.3925286203228279,-0.6257295573052645,1.623176179314646,-1.315246174406957,0.9670119136618348,0.2224334357534765,0.19067127264620573,-0.8287924672030076,0.12695555655645674,-0.19560956934146895,0.030894617027511038,-0.2609563355332265,0.6916031594494587,0.6607309570482511,-0.2609563355332265,-0.03347806686168351,-0.4920008457387619,0.5366787829519797,-0.098122333905974,-0.16304347134508207,-0.3595238272390506,-0.6593637349435877,-0.22824695247054547,0.2857692407025649,-0.22824695247054547,0.25413257026133235,3.257840018273795,-0.03347806686168351,-0.3595238272390506,1.943054324684516,-0.931491220478586,1.08805639508316,0.12695555655645674,1.387215394486587,0.25413257026133235,-0.16304347134508207,-0.22824695247054547,0.31734400267200297,0.19067127264620573,-0.6930805097254553,-0.22824695247054547,0.5988184783374502,0.6298028841948623,0.7838890695289682,0.4117022638315761,-0.0012581004565036626,0.2857692407025649,-0.098122333905974,0.3803099800917596,5.940175937290734,-0.13054795621506413,2.2010744460285183,0.6607309570482511,0.25413257026133235,-0.7947358122572576,0.7224199472328477,-1.174345720866778,0.6607309570482511,-0.098122333905974,1.7692119702003737,-0.6593637349435877,-0.13054795621506413,0.030894617027511038,-0.16304347134508207,3.2306497156014906,2.2579809707838456,-0.03347806686168351,0.19067127264620573
3,643
Toe walking
8
23
2.893916
0.003805
Q99720,P07602,Q8TD16,O95831,P02545,Q01082,Q9H9S5,O43681
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,69,272,47,265,365,347,118
118,47,265,394,69,754,2232,849,2073,1387,2349,2880,365,1895,959,2946,3089,272,976,2,1581,347,1064
1.7982903969638317,3.0119856905575273,1.0578712931665288,0.7838890695289682,2.427791890653298,0.4117022638315761,-0.22824695247054547,0.34885740302862467,-0.16304347134508207,0.09500082791205905,-0.2609563355332265,-0.525313577596298,0.845141841466991,-0.098122333905974,0.2857692407025649,-0.5587053640309138,-0.6593637349435877,1.0578712931665288,0.2857692407025649,8.21990109917503,0.030894617027511038,0.9061816816409076,0.25413257026133235
3,643
Receptor
14
43
2.891009
0.00384
P11717,Q99720,Q14108,P20645,O15118,O15173,Q8WTV0,P02786,O75787,Q14739,Q5KU26,Q99523,P30825,P10586
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
154,2,255,37,252,199,8,409,296,416,396,114,54,119
932,1606,1072,252,199,296,3617,409,3218,750,1012,1790,3069,2511,119,1082,154,2760,942,37,562,54,889,2162,1893,1993,255,416,418,662,396,8,2103,114,3235,2,2120,1593,3432,3585,833,3381,1951
0.2857692407025649,-0.0012581004565036626,0.2224334357534765,1.08805639508316,1.327766595224347,0.9973494401983068,-2.342454069604444,0.7531817696547146,-0.7947358122572576,0.4117022638315761,0.25413257026133235,-0.06576592628969985,-0.6593637349435877,-0.3265940252928932,1.7982903969638317,0.2224334357534765,1.5350292358486646,-0.4587663248239629,0.2857692407025649,3.284999162596966,0.5677772700633923,2.707887319665007,0.31734400267200297,-0.19560956934146895,-0.098122333905974,-0.13054795621506413,1.08805639508316,0.7531817696547146,0.7531817696547146,0.47430803058067816,0.7838890695289682,5.940175937290734,-0.16304347134508207,1.8563207862044178,-0.7947358122572576,8.21990109917503,-0.16304347134508207,0.030894617027511038,-1.069696640684267,-1.6741333670170677,0.3803099800917596,-0.9659039071751861,-0.098122333905974
3,643
Positive regulation of nf kappab transcription factor activity
11
32
2.84752
0.004406
P19474,P02786,O60858,P14373,P05067,O75955,Q96HY6,P41440,P32929,Q13049,P60900
Processes and pathways
GO Biological process
msigdb_gobp
36,409,80,395,29,249,384,90,187,188,283
2050,1001,2502,80,249,409,29,2055,2511,1704,395,36,2225,437,1149,187,1296,90,3442,283,3118,1394,188,3122,2672,1315,1563,2460,572,1834,384,1431
-0.16304347134508207,0.25413257026133235,-0.3265940252928932,2.2579809707838456,1.118191455601226,0.7531817696547146,3.6353042018995785,-0.16304347134508207,-0.3265940252928932,-0.03347806686168351,0.7838890695289682,3.3662912544280115,-0.22824695247054547,0.7224199472328477,0.19067127264620573,1.387215394486587,0.12695555655645674,2.058127752852981,-1.104482929673742,1.027635769907882,-0.6930805097254553,0.09500082791205905,1.387215394486587,-0.6930805097254553,-0.3925286203228279,0.12695555655645674,0.030894617027511038,-0.29373844618932715,0.5677772700633923,-0.06576592628969985,0.8145422833591529,0.09500082791205905
3,643
Transporter activity
44
217
2.834504
0.00459
Q9BSK2,Q86VD7,O15118,Q8WTV0,Q6NT16,Q96H78,Q8IXU6,O43772,Q01650,Q7L0J3,Q9H813,O75027,P39210,Q7KZN9,P11166,P21796,Q8N4V1,O95563,Q70HW3,Q9NWR8,Q9UBX3,Q9Y487,O43676,P53985,P16615,O75251,O14678,Q6P4Q7,Q8NHS3,Q9HD20,P30825,P03886,O15173,P00846,P45880,Q93050,O75964,P41440,Q9Y6M7,Q9H4L5,Q13423,P25705,O43681,O75380
Functions
GO Molecular function
msigdb_gomf
260,256,252,8,10,274,12,13,143,17,150,21,267,286,279,34,167,152,285,305,306,43,163,44,172,294,176,316,52,183,54,62,199,74,78,82,214,90,361,100,352,237,118,120
2751,2321,1208,3065,646,2408,453,2047,176,2793,1954,252,199,1003,1695,2411,163,3494,118,13,2754,2795,21,294,471,120,1006,3145,1450,1218,214,1698,1453,3146,651,2649,882,1372,940,152,792,500,2705,559,74,62,2967,703,1962,2054,3149,1873,2141,1012,3191,3106,1374,704,1618,1144,1291,279,2331,1145,2223,172,2869,3544,3071,1015,561,2061,3422,34,1797,2517,3112,237,1622,2971,3615,54,1713,2342,1226,1624,847,2661,267,90,78,1298,3487,2934,795,3263,459,3607,460,535,1980,2073,44,440,711,2522,1471,3159,2587,2807,351,1477,2163,2812,3079,143,2771,1028,506,352,1728,624,3301,963,1649,662,2603,2820,3042,2274,1657,10,2366,3456,719,316,285,286,17,256,2277,1177,12,671,167,1915,1501,2949,3525,52,573,2829,8,2103,82,1336,3634,3616,574,274,2906,2907,1674,1262,1263,2021,682,2737,2292,3179,577,260,3334,1347,984,2841,2115,549,2388,733,1350,100,150,1057,405,553,183,822,1193,2844,2120,2485,2912,3182,305,1432,2785,306,3463,991,2401,924,2788,2959,1596,2205,3380,43,2316,1859,1067,1280,693,694,3315,361,3537
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3,643
Serine hydrolase activity
9
22
2.801543
0.005086
Q9H3G5,Q9HB40,P42785,Q4J6C6,O75976,Q6PIU2,Q16740,O14773,P10619
Functions
GO Molecular function
msigdb_gomf
359,35,4,135,206,419,113,391,59
391,206,59,3109,2659,1973,4,3201,1980,1632,2254,113,1652,135,1042,3045,419,2005,2989,491,359,35
0.7838890695289682,1.2979715997804608,2.5402599154147643,-0.6930805097254553,-0.3925286203228279,-0.13054795621506413,6.233993929662534,-0.7607655898218467,-0.13054795621506413,-0.0012581004565036626,-0.22824695247054547,1.8563207862044178,-0.0012581004565036626,1.6524701228970238,0.25413257026133235,-0.6257295573052645,0.7531817696547146,-0.13054795621506413,-0.5921770650124923,0.6607309570482511,0.8756881681175116,3.447308651903207
3,643
Abnormality of the gallbladder
11
42
2.79602
0.005174
P22830,P04066,P07602,Q15056,Q15437,Q71SY5,O43681,O00192,Q9UBM7,O96028,Q9UIG0
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
0,228,69,462,110,144,118,389,289,87,527
2319,389,118,1610,1451,1372,87,703,228,2922,2509,69,2923,3023,1707,1878,2515,0,3199,1464,1298,1301,2157,2074,3408,1089,803,1562,462,110,569,144,3132,1334,2100,1048,2478,1064,289,527,2309,1603
-0.2609563355332265,0.7838890695289682,1.7982903969638317,-0.0012581004565036626,0.06298071889501843,0.09500082791205905,2.11542427763213,0.44303477605405855,1.1783129469800828,-0.5587053640309138,-0.3265940252928932,2.427791890653298,-0.5587053640309138,-0.6257295573052645,-0.03347806686168351,-0.098122333905974,-0.3265940252928932,9.72862962082004,-0.7607655898218467,0.06298071889501843,0.12695555655645674,0.12695555655645674,-0.19560956934146895,-0.16304347134508207,-1.0350054838275398,0.2224334357534765,0.3803099800917596,0.030894617027511038,0.6916031594494587,1.914184390727662,0.5677772700633923,1.5938382520831849,-0.6930805097254553,0.12695555655645674,-0.16304347134508207,0.25413257026133235,-0.29373844618932715,0.25413257026133235,1.027635769907882,0.6298028841948623,-0.22824695247054547,0.030894617027511038
3,643
Platyspondyly
12
36
2.79061
0.005261
P16278,O00754,P04066,Q8WVQ1,Q96L58,Q7RTS9,Q14739,O95831,P08236,Q96HY6,P00813,P48735
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
155,435,228,423,303,11,416,47,455,384,56,339
3186,435,1958,2412,1284,3288,47,56,228,455,155,2337,2516,2147,1881,707,339,1886,1026,2257,1989,416,900,2728,1246,2366,1905,11,909,423,1112,384,303,3096,524,2312
-0.7607655898218467,0.7224199472328477,-0.13054795621506413,-0.29373844618932715,0.12695555655645674,-0.8629365633590367,3.0119856905575273,2.6800374279695216,1.1783129469800828,0.6916031594494587,1.5350292358486646,-0.2609563355332265,-0.3265940252928932,-0.19560956934146895,-0.098122333905974,0.44303477605405855,0.9061816816409076,-0.098122333905974,0.25413257026133235,-0.22824695247054547,-0.13054795621506413,0.7531817696547146,0.31734400267200297,-0.42560918711049844,0.15884550726049723,-0.2609563355332265,-0.098122333905974,5.543953911878619,0.31734400267200297,0.7531817696547146,0.2224334357534765,0.8145422833591529,0.9973494401983068,-0.6593637349435877,0.6298028841948623,-0.22824695247054547
3,643
Azurophil granule
20
75
2.790333
0.005265
P78371,P42785,P10253,P06280,P16278,Q07065,P15586,Q92542,P10619,O00754,P07602,P08236,P04066,O00584,P61916,O15260,Q9BTY2,P15291,O43681,Q9NQX7
Localization
GO Cellular component
msigdb_gocc
378,4,266,153,155,173,410,317,59,435,69,455,228,103,351,108,115,112,118,122
2322,103,435,108,586,118,2700,1078,1456,2704,228,153,1013,3191,1701,69,3538,455,266,59,3219,1964,1082,2332,112,410,155,2869,3294,563,3197,3324,707,3200,4,2935,2237,3265,1300,476,1805,1632,1806,2349,1023,351,2161,378,2813,2938,173,1238,2087,2532,2001,1663,1916,317,1417,1835,1507,2111,3179,683,115,3211,2115,2693,122,2912,2202,1064,1199,2492,609
-0.2609563355332265,1.943054324684516,0.7224199472328477,1.914184390727662,0.5366787829519797,1.7982903969638317,-0.42560918711049844,0.2224334357534765,0.06298071889501843,-0.42560918711049844,1.1783129469800828,1.5350292358486646,0.25413257026133235,-0.7607655898218467,-0.03347806686168351,2.427791890653298,-1.3862754857551036,0.6916031594494587,1.0578712931665288,2.5402599154147643,-0.7947358122572576,-0.13054795621506413,0.2224334357534765,-0.2609563355332265,1.8563207862044178,0.7531817696547146,1.5350292358486646,-0.525313577596298,-0.8629365633590367,0.5677772700633923,-0.7607655898218467,-0.8971691305719629,0.44303477605405855,-0.7607655898218467,6.233993929662534,-0.5587053640309138,-0.22824695247054547,-0.8287924672030076,0.12695555655645674,0.6607309570482511,-0.06576592628969985,-0.0012581004565036626,-0.06576592628969985,-0.2609563355332265,0.25413257026133235,0.8756881681175116,-0.19560956934146895,0.8145422833591529,-0.4920008457387619,-0.5587053640309138,1.4760406150941263,0.15884550726049723,-0.16304347134508207,-0.3265940252928932,-0.13054795621506413,-0.0012581004565036626,-0.098122333905974,0.9670119136618348,0.09500082791205905,-0.06576592628969985,0.06298071889501843,-0.16304347134508207,-0.726880811724572,0.47430803058067816,1.8563207862044178,-0.7607655898218467,-0.16304347134508207,-0.3925286203228279,1.7692119702003737,-0.525313577596298,-0.19560956934146895,0.25413257026133235,0.19067127264620573,-0.29373844618932715,0.5366787829519797
3,643
Transport of small molecules
39
171
2.788968
0.005288
O15118,Q8WTV0,P20618,P30519,Q01650,O75027,P28072,P60900,P11166,P21796,Q8N4V1,O00231,Q70HW3,Q9UBX3,Q9NWR8,Q9Y487,P28074,P28070,P53985,P16615,P02786,Q6PIU2,Q9HD20,Q9UBI6,P30825,Q9BPX6,P49721,P55011,P45880,P51790,Q93050,P51798,Q9Y6M7,P61916,Q13555,Q9UNS2,Q9H4I9,Q99436,Q8IYU8
Processes and pathways
Reactome Pathways
msigdb_reactome
252,8,137,14,143,21,146,283,279,34,167,278,285,306,305,43,41,164,44,172,409,419,183,451,54,320,60,440,78,459,82,460,361,351,105,106,244,121,257
278,3316,3249,646,1135,3142,252,1003,1609,21,2137,3144,1615,3254,2417,2798,1372,2328,3617,1787,409,1962,2054,3149,1873,1010,3150,1374,704,1702,653,1377,279,2331,1145,751,172,3406,2577,1015,2514,137,2061,3422,1795,34,2517,2762,1461,1621,2802,563,3222,164,146,41,1622,14,3424,54,2342,2229,1225,846,889,3425,2932,1624,3578,2661,1464,1975,3034,78,2153,2878,60,1229,459,3607,460,2348,44,3075,440,3267,2349,283,949,2587,351,3163,2523,3078,2251,3202,1477,1392,952,143,3269,658,1561,2985,1093,2672,105,2597,3540,1485,963,662,965,3042,1041,3456,419,285,1741,1177,257,167,1745,2949,3525,573,2829,8,2468,2013,2284,82,1050,2907,1264,121,1507,3235,2737,2292,320,2113,3056,2841,2115,491,3533,244,183,822,1193,2844,2485,305,451,741,306,526,2401,2308,554,2788,2563,106,2205,43,608,1280,694,876,361
1.027635769907882,-0.8971691305719629,-0.8287924672030076,0.47430803058067816,0.19067127264620573,-0.726880811724572,1.08805639508316,0.25413257026133235,-0.0012581004565036626,4.373525061543824,-0.19560956934146895,-0.726880811724572,-0.0012581004565036626,-0.8287924672030076,-0.29373844618932715,-0.4920008457387619,0.09500082791205905,-0.2609563355332265,-2.342454069604444,-0.06576592628969985,0.7531817696547146,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,-0.098122333905974,0.25413257026133235,-0.726880811724572,0.09500082791205905,0.44303477605405855,-0.03347806686168351,0.47430803058067816,0.09500082791205905,1.027635769907882,-0.2609563355332265,0.19067127264620573,0.4117022638315761,1.4760406150941263,-1.0350054838275398,-0.3595238272390506,0.25413257026133235,-0.3265940252928932,1.623176179314646,-0.16304347134508207,-1.069696640684267,-0.06576592628969985,3.528055524230381,-0.3265940252928932,-0.4587663248239629,0.06298071889501843,-0.0012581004565036626,-0.4920008457387619,0.5677772700633923,-0.7947358122572576,1.5055575321040489,1.5644560394229112,3.2306497156014906,-0.0012581004565036626,5.1928477731586264,-1.069696640684267,2.707887319665007,-0.2609563355332265,-0.22824695247054547,0.15884550726049723,0.34885740302862467,0.31734400267200297,-1.069696640684267,-0.5587053640309138,-0.0012581004565036626,-1.63783022894056,-0.3925286203228279,0.06298071889501843,-0.13054795621506413,-0.6257295573052645,2.286376867508823,-0.19560956934146895,-0.525313577596298,2.5402599154147643,0.15884550726049723,0.6916031594494587,-2.042021033479733,0.6916031594494587,-0.2609563355332265,3.1215736355280526,-0.6593637349435877,0.7224199472328477,-0.8287924672030076,-0.2609563355332265,1.027635769907882,0.2857692407025649,-0.3595238272390506,0.8756881681175116,-0.726880811724572,-0.3265940252928932,-0.6593637349435877,-0.22824695247054547,-0.7607655898218467,0.06298071889501843,0.09500082791205905,0.2857692407025649,1.5938382520831849,-0.8287924672030076,0.47430803058067816,0.030894617027511038,-0.5921770650124923,0.2224334357534765,-0.3925286203228279,1.943054324684516,-0.3595238272390506,-1.3862754857551036,0.06298071889501843,0.2857692407025649,0.47430803058067816,0.2857692407025649,-0.6257295573052645,0.25413257026133235,-1.1393655482262741,0.7531817696547146,1.027635769907882,-0.03347806686168351,0.19067127264620573,1.08805639508316,1.5055575321040489,-0.03347806686168351,-0.5587053640309138,-1.315246174406957,0.5677772700633923,-0.4920008457387619,5.940175937290734,-0.29373844618932715,-0.13054795621506413,-0.22824695247054547,2.2010744460285183,0.25413257026133235,-0.525313577596298,0.15884550726049723,1.7692119702003737,0.06298071889501843,-0.7947358122572576,-0.42560918711049844,-0.22824695247054547,0.9670119136618348,-0.16304347134508207,-0.6257295573052645,-0.4920008457387619,-0.16304347134508207,0.6607309570482511,-1.3507131280591325,1.1482768495977804,1.4168698692908286,0.3803099800917596,0.19067127264620573,-0.4920008457387619,-0.29373844618932715,0.9973494401983068,0.7224199472328477,0.44303477605405855,0.9973494401983068,0.6298028841948623,-0.2609563355332265,-0.22824695247054547,0.5988184783374502,-0.4587663248239629,-0.3265940252928932,1.943054324684516,-0.19560956934146895,3.2306497156014906,0.5366787829519797,0.15884550726049723,0.47430803058067816,0.34885740302862467,0.8756881681175116
3,643
Anion transport
31
84
2.781916
0.005404
Q14728,Q86VD7,P14174,Q01650,Q7L0J3,Q9H813,Q9HC21,Q9Y619,Q9Y666,Q9UHG3,P11166,P21796,O00400,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,P80404,Q15758,P30825,O43865,P55011,Q9H2D1,P07602,P45880,P51790,P51798,P41440,Q9Y6M7,O43681
Processes and pathways
GO Biological process
msigdb_gobp
624,256,15,143,17,150,553,693,694,430,279,34,646,152,306,577,44,573,413,662,54,55,440,733,69,78,459,460,90,361,118
3065,646,2793,2049,1003,118,2754,55,2219,1450,3068,152,2508,1962,1873,3218,69,1374,704,1144,3219,279,2331,1145,15,34,1622,3615,54,2342,90,78,459,3607,460,2073,44,1555,440,413,2812,143,2771,1395,2672,624,1317,765,963,662,3124,3042,2274,1657,2366,3456,17,256,1177,573,2829,2906,2907,1262,2292,577,2841,1424,733,150,1057,553,1844,1432,1064,306,430,924,2205,2640,693,694,3315,361
-0.6593637349435877,0.47430803058067816,-0.4920008457387619,-0.16304347134508207,0.25413257026133235,1.7982903969638317,-0.4587663248239629,2.6800374279695216,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,-0.3265940252928932,-0.13054795621506413,-0.098122333905974,-0.7947358122572576,2.427791890653298,0.09500082791205905,0.44303477605405855,0.19067127264620573,-0.7947358122572576,1.027635769907882,-0.2609563355332265,0.19067127264620573,4.964849362308119,3.528055524230381,-0.0012581004565036626,-2.2291720974867153,2.707887319665007,-0.2609563355332265,2.058127752852981,2.286376867508823,0.6916031594494587,-2.042021033479733,0.6916031594494587,-0.16304347134508207,3.1215736355280526,0.030894617027511038,0.7224199472328477,0.7531817696547146,-0.4920008457387619,1.5938382520831849,-0.4587663248239629,0.09500082791205905,-0.3925286203228279,0.5055225334229401,0.12695555655645674,0.4117022638315761,0.2857692407025649,0.47430803058067816,-0.6930805097254553,-0.6257295573052645,-0.22824695247054547,-0.0012581004565036626,-0.2609563355332265,-1.1393655482262741,4.734981990697083,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.4920008457387619,-0.525313577596298,-0.525313577596298,0.15884550726049723,-0.22824695247054547,0.5677772700633923,-0.4920008457387619,0.09500082791205905,0.44303477605405855,1.5644560394229112,0.25413257026133235,0.5988184783374502,-0.06576592628969985,0.09500082791205905,0.25413257026133235,0.9973494401983068,0.7531817696547146,0.31734400267200297,-0.19560956934146895,-0.3595238272390506,0.47430803058067816,0.47430803058067816,-0.8629365633590367,0.8756881681175116
3,643
Carboxylic acid transport
7
38
2.762729
0.005732
P07602,P53985,P14174,Q01650,Q7L0J3,P30825,P41440
Processes and pathways
GO Biological process
msigdb_gobp
69,44,15,143,17,54,90
2793,2049,1003,2219,1450,3068,152,2508,3218,69,704,15,1622,54,2342,90,2073,44,440,413,143,2771,1317,765,662,3456,17,1177,2829,2906,2907,577,733,1057,1064,306,924,693
-0.4920008457387619,-0.16304347134508207,0.25413257026133235,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,-0.3265940252928932,-0.7947358122572576,2.427791890653298,0.44303477605405855,4.964849362308119,-0.0012581004565036626,2.707887319665007,-0.2609563355332265,2.058127752852981,-0.16304347134508207,3.1215736355280526,0.7224199472328477,0.7531817696547146,1.5938382520831849,-0.4587663248239629,0.12695555655645674,0.4117022638315761,0.47430803058067816,-1.1393655482262741,4.734981990697083,0.19067127264620573,-0.4920008457387619,-0.525313577596298,-0.525313577596298,0.5677772700633923,0.44303477605405855,0.25413257026133235,0.25413257026133235,0.9973494401983068,0.31734400267200297,0.47430803058067816
3,643
Sensorimotor neuropathy
13
40
2.757459
0.005825
Q9NR77,P03886,O60313,P07602,P00846,Q7LG56,O95831,Q5KU26,P39210,P41440,Q9Y2R0,P07196,P00403
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,62,529,69,74,464,47,396,267,90,219,125,559
1605,2212,529,1616,47,2705,559,74,62,2967,2054,125,69,1221,2065,1971,2711,267,2232,90,1885,2238,2242,2349,2880,1238,3328,2091,396,668,464,859,813,2622,1053,32,3006,1064,219,608
-0.0012581004565036626,-0.22824695247054547,0.5988184783374502,-0.0012581004565036626,3.0119856905575273,-0.42560918711049844,0.5677772700633923,2.371337868662573,2.512197372488192,-0.5921770650124923,-0.16304347134508207,1.7400910153055076,2.427791890653298,0.15884550726049723,-0.16304347134508207,-0.13054795621506413,-0.42560918711049844,1.0578712931665288,-0.22824695247054547,2.058127752852981,-0.098122333905974,-0.22824695247054547,-0.22824695247054547,-0.2609563355332265,-0.525313577596298,0.15884550726049723,-0.8971691305719629,-0.16304347134508207,0.7838890695289682,0.47430803058067816,0.6916031594494587,0.34885740302862467,0.3803099800917596,-0.3595238272390506,0.25413257026133235,3.6085359292973544,-0.5921770650124923,0.25413257026133235,1.2382387072449188,0.5366787829519797
3,643
Regulation of lymphocyte activation
8
58
2.755989
0.005851
Q9NUQ9,Q9HCL2,P22466,P14174,P12956,P30825,P00813,O96028
Processes and pathways
GO Biological process
msigdb_gobp
102,5,38,15,83,54,56,87
1952,2792,2410,2215,2860,3365,87,2757,56,409,2508,590,1081,1377,3256,1082,83,15,3629,1084,38,437,138,54,592,2874,708,1547,1548,3440,3344,1390,3038,1815,1395,2526,2267,1315,1404,1100,2535,969,1737,468,2015,978,2619,681,914,1339,2621,1928,5,492,638,102,2788,555
-0.13054795621506413,-0.4920008457387619,-0.29373844618932715,-0.22824695247054547,-0.525313577596298,-0.9659039071751861,2.11542427763213,-0.4587663248239629,2.6800374279695216,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.2224334357534765,0.09500082791205905,-0.8287924672030076,0.2224334357534765,2.172563346869744,4.964849362308119,-2.997816021189173,0.2224334357534765,3.257840018273795,0.7224199472328477,1.623176179314646,2.707887319665007,0.5366787829519797,-0.525313577596298,0.44303477605405855,0.030894617027511038,0.030894617027511038,-1.104482929673742,-0.931491220478586,0.09500082791205905,-0.6257295573052645,-0.06576592628969985,0.09500082791205905,-0.3265940252928932,-0.22824695247054547,0.12695555655645674,0.09500082791205905,0.2224334357534765,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.6916031594494587,-0.13054795621506413,0.2857692407025649,-0.3595238272390506,0.47430803058067816,0.31734400267200297,0.12695555655645674,-0.3595238272390506,-0.098122333905974,6.233993929662534,0.6607309570482511,0.5055225334229401,1.9718833674139287,-0.4587663248239629,0.5988184783374502
3,643
Organic acid transmembrane transport
10
35
2.751665
0.005929
P11166,O95563,Q9UBX3,P23786,P53985,O43772,Q01650,O14678,P30825,P41440
Processes and pathways
GO Biological process
msigdb_gobp
279,152,306,200,44,13,143,176,54,90
176,13,2219,1450,3068,152,3218,1374,704,279,200,1622,54,592,364,1224,2342,90,3264,2073,44,143,2771,1317,662,1177,2829,2906,2907,577,733,1057,306,924,693
1.446478167816503,5.243267115697605,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,-0.7947358122572576,0.09500082791205905,0.44303477605405855,1.027635769907882,1.327766595224347,-0.0012581004565036626,2.707887319665007,0.5366787829519797,0.845141841466991,0.15884550726049723,-0.2609563355332265,2.058127752852981,-0.8287924672030076,-0.16304347134508207,3.1215736355280526,1.5938382520831849,-0.4587663248239629,0.12695555655645674,0.47430803058067816,0.19067127264620573,-0.4920008457387619,-0.525313577596298,-0.525313577596298,0.5677772700633923,0.44303477605405855,0.25413257026133235,0.9973494401983068,0.31734400267200297,0.47430803058067816
3,643
Membrane lipid metabolic process
13
44
2.745473
0.006042
P16278,P04066,P07602,Q8NBX0,P50897,Q16739,Q8NCC3,O60512,Q9NWW5,Q9NRA0,Q969N2,Q96G23,P06280
Processes and pathways
GO Biological process
msigdb_gobp
155,228,69,331,72,330,28,85,251,227,318,159,153
746,2212,2216,85,1777,701,703,228,153,1013,69,3538,155,2869,1797,502,1968,72,2938,2166,3473,330,1900,905,569,809,331,28,1921,318,159,2020,1117,426,2388,227,251,1758,2488,1432,1064,2847,1199,2565
0.4117022638315761,-0.22824695247054547,-0.22824695247054547,2.144013371443563,-0.06576592628969985,0.44303477605405855,0.44303477605405855,1.1783129469800828,1.5350292358486646,0.25413257026133235,2.427791890653298,-1.3862754857551036,1.5350292358486646,-0.525313577596298,-0.06576592628969985,0.6298028841948623,-0.13054795621506413,2.399583395405736,-0.5587053640309138,-0.19560956934146895,-1.174345720866778,0.9366227945511973,-0.098122333905974,0.31734400267200297,0.5677772700633923,0.3803099800917596,0.9366227945511973,3.768713037747525,-0.098122333905974,0.9670119136618348,1.5350292358486646,-0.13054795621506413,0.2224334357534765,0.7531817696547146,-0.2609563355332265,1.2083001127798034,1.118191455601226,-0.03347806686168351,-0.29373844618932715,0.09500082791205905,0.25413257026133235,-0.4920008457387619,0.19067127264620573,-0.3265940252928932
3,643
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
8
20
2.74323
0.006084
Q02818,P07942,Q06481,Q8NBJ4,Q07065,O43493,Q9BTY2,P05067
Processes and pathways
Reactome Pathways
msigdb_reactome
65,126,39,75,173,142,115,29
142,2698,881,29,3150,126,3257,1706,2513,843,65,39,173,1238,2448,3583,1246,301,75,115
1.5938382520831849,-0.42560918711049844,0.31734400267200297,3.6353042018995785,-0.726880811724572,1.7109272480905777,-0.8287924672030076,-0.03347806686168351,-0.3265940252928932,0.34885740302862467,2.4840986629825825,3.257840018273795,1.4760406150941263,0.15884550726049723,-0.29373844618932715,-1.6741333670170677,0.15884550726049723,0.9973494401983068,2.371337868662573,1.8563207862044178
3,643
Secretory granule membrane
14
75
2.739837
0.006147
P11717,P42785,P07602,Q9NQX7,Q06481,P84095,O15260,O75787,P30519,Q07065,Q93050,P15291,P10253,O75592
Localization
GO Cellular component
msigdb_gocc
154,4,69,122,39,139,108,296,14,173,82,112,266,186
932,108,1003,789,1534,1613,2700,1078,186,296,2798,1456,1872,1012,69,266,532,3219,1082,154,2332,112,3552,1084,560,563,14,3424,2343,889,3200,4,709,795,1300,2156,476,2241,596,1890,2075,3268,1156,3120,139,39,173,1395,2528,3348,2598,1315,3611,3042,2604,667,2001,1909,1916,973,317,82,482,3447,3179,1933,2115,1354,122,2912,1064,1199,1599,1280,1860
0.2857692407025649,1.914184390727662,0.25413257026133235,0.3803099800917596,0.030894617027511038,-0.0012581004565036626,-0.42560918711049844,0.2224334357534765,1.387215394486587,0.9973494401983068,-0.4920008457387619,0.06298071889501843,-0.098122333905974,0.25413257026133235,2.427791890653298,1.0578712931665288,0.5988184783374502,-0.7947358122572576,0.2224334357534765,1.5350292358486646,-0.2609563355332265,1.8563207862044178,-1.4576838354723742,0.2224334357534765,0.5677772700633923,0.5677772700633923,5.1928477731586264,-1.069696640684267,-0.2609563355332265,0.31734400267200297,-0.7607655898218467,6.233993929662534,0.44303477605405855,0.3803099800917596,0.12695555655645674,-0.19560956934146895,0.6607309570482511,-0.22824695247054547,0.5366787829519797,-0.098122333905974,-0.16304347134508207,-0.8287924672030076,0.19067127264620573,-0.6930805097254553,1.623176179314646,3.257840018273795,1.4760406150941263,0.09500082791205905,-0.3265940252928932,-0.931491220478586,-0.3595238272390506,0.12695555655645674,-2.1540615170130093,-0.6257295573052645,-0.3595238272390506,0.47430803058067816,-0.13054795621506413,-0.098122333905974,-0.098122333905974,0.2857692407025649,0.9670119136618348,2.2010744460285183,0.6607309570482511,-1.104482929673742,-0.726880811724572,-0.098122333905974,-0.16304347134508207,0.12695555655645674,1.7692119702003737,-0.525313577596298,0.25413257026133235,0.19067127264620573,0.030894617027511038,0.15884550726049723,-0.06576592628969985
3,643
Slowly progressive
12
58
2.731523
0.006304
Q9NR77,Q99720,Q8IV08,O00584,O75787,O95831,P02545,O43707,O14773,P41440,Q13049,P07196
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,2,73,103,296,47,265,325,391,90,188,125
1605,103,391,1000,2571,325,2136,3404,296,2417,791,47,265,2054,125,2331,1876,2064,1295,1971,2711,2662,90,2432,946,849,1155,1301,1387,2585,188,415,2087,2529,477,2091,1039,1320,3043,3502,2452,2729,2946,73,859,813,2830,3177,2,2112,1581,3533,32,1849,1850,2785,2960,608
-0.0012581004565036626,1.943054324684516,0.7838890695289682,0.25413257026133235,-0.3595238272390506,0.9366227945511973,-0.19560956934146895,-1.0350054838275398,0.9973494401983068,-0.29373844618932715,0.3803099800917596,3.0119856905575273,1.0578712931665288,-0.16304347134508207,1.7400910153055076,-0.2609563355332265,-0.098122333905974,-0.16304347134508207,0.12695555655645674,-0.13054795621506413,-0.42560918711049844,-0.3925286203228279,2.058127752852981,-0.29373844618932715,0.2857692407025649,0.34885740302862467,0.19067127264620573,0.12695555655645674,0.09500082791205905,-0.3595238272390506,1.387215394486587,0.7531817696547146,-0.16304347134508207,-0.3265940252928932,0.6607309570482511,-0.16304347134508207,0.25413257026133235,0.12695555655645674,-0.6257295573052645,-1.244601121096576,-0.29373844618932715,-0.42560918711049844,-0.5587053640309138,2.399583395405736,0.34885740302862467,0.3803099800917596,-0.4920008457387619,-0.726880811724572,8.21990109917503,-0.16304347134508207,0.030894617027511038,-1.3507131280591325,3.6085359292973544,-0.06576592628969985,-0.06576592628969985,-0.4587663248239629,-0.5587053640309138,0.5366787829519797
3,643
Apical plasma membrane
15
54
2.725438
0.006422
P11166,P55011,P26038,P53985,O75787,Q01650,P51790,Q9Y4G8,O14523,P30825,O43865,P78536,O75955,P41440,Q9Y6M7
Localization
GO Cellular component
msigdb_gocc
279,440,501,44,296,143,459,81,453,54,55,216,249,90,361
1770,1207,453,2793,2571,1003,55,1367,296,249,2508,1962,2054,3149,1374,704,2923,1457,279,3321,941,843,1015,2061,2517,501,54,2342,2068,1624,1544,2661,90,459,44,3075,440,2587,216,143,2443,1315,963,1650,541,2460,2737,2292,1354,2695,2912,1520,81,361
-0.06576592628969985,0.15884550726049723,0.6916031594494587,-0.4920008457387619,-0.3595238272390506,0.25413257026133235,2.6800374279695216,0.09500082791205905,0.9973494401983068,1.118191455601226,-0.3265940252928932,-0.13054795621506413,-0.16304347134508207,-0.726880811724572,0.09500082791205905,0.44303477605405855,-0.5587053640309138,0.06298071889501843,1.027635769907882,-0.8971691305719629,0.2857692407025649,0.34885740302862467,0.25413257026133235,-0.16304347134508207,-0.3265940252928932,0.6298028841948623,2.707887319665007,-0.2609563355332265,-0.16304347134508207,-0.0012581004565036626,0.030894617027511038,-0.3925286203228279,2.058127752852981,0.6916031594494587,3.1215736355280526,-0.6593637349435877,0.7224199472328477,-0.3595238272390506,1.2382387072449188,1.5938382520831849,-0.29373844618932715,0.12695555655645674,0.2857692407025649,-0.0012581004565036626,0.5988184783374502,-0.29373844618932715,-0.42560918711049844,-0.22824695247054547,0.12695555655645674,-0.3925286203228279,-0.525313577596298,0.06298071889501843,2.2579809707838456,0.8756881681175116
3,643
Cell recognition
6
26
2.712015
0.006688
P78371,Q9BY67,Q8WTV0,P45880,P15291,P05067
Processes and pathways
GO Biological process
msigdb_gobp
378,304,8,78,112,29
1606,2409,2922,29,112,1084,2334,501,889,78,1467,1468,2237,1470,2437,378,1647,396,3305,8,1184,2377,1342,304,1847,1443
-0.0012581004565036626,-0.29373844618932715,-0.5587053640309138,3.6353042018995785,1.8563207862044178,0.2224334357534765,-0.2609563355332265,0.6298028841948623,0.31734400267200297,2.286376867508823,0.06298071889501843,0.06298071889501843,-0.22824695247054547,0.06298071889501843,-0.29373844618932715,0.8145422833591529,-0.0012581004565036626,0.7838890695289682,-0.8629365633590367,5.940175937290734,0.19067127264620573,-0.2609563355332265,0.12695555655645674,0.9973494401983068,-0.06576592628969985,0.09500082791205905
3,643
Transmembrane receptor protein serine threonine kinase signaling pathway
12
54
2.705191
0.006827
Q8WUH2,P49354,Q06481,Q92896,Q9UIQ6,Q8N0X7,P08670,Q01082,Q8N3R9,Q13573,Q8N1F7,P78536
Processes and pathways
GO Biological process
msigdb_gobp
133,229,39,136,42,421,104,365,148,88,342,216
646,2322,2049,2502,1288,3218,1457,104,1791,1459,3322,3520,1384,1296,229,1155,3299,2436,1025,216,365,1893,2081,39,1994,2671,88,1484,1163,2270,2271,1097,1098,419,1909,421,342,148,1664,133,136,2378,1049,1923,1261,2023,2026,42,2562,1855,3138,744,2406,1132
0.47430803058067816,-0.2609563355332265,-0.16304347134508207,-0.3265940252928932,0.12695555655645674,-0.7947358122572576,0.06298071889501843,1.943054324684516,-0.06576592628969985,0.06298071889501843,-0.8971691305719629,-1.315246174406957,0.09500082791205905,0.12695555655645674,1.1783129469800828,0.19067127264620573,-0.8629365633590367,-0.29373844618932715,0.25413257026133235,1.2382387072449188,0.845141841466991,-0.098122333905974,-0.16304347134508207,3.257840018273795,-0.13054795621506413,-0.3925286203228279,2.11542427763213,0.06298071889501843,0.19067127264620573,-0.22824695247054547,-0.22824695247054547,0.2224334357534765,0.2224334357534765,0.7531817696547146,-0.098122333905974,0.7531817696547146,0.9061816816409076,1.5644560394229112,-0.0012581004565036626,1.6817203809689008,1.6524701228970238,-0.2609563355332265,0.25413257026133235,-0.098122333905974,0.15884550726049723,-0.13054795621506413,-0.13054795621506413,3.2306497156014906,-0.3265940252928932,-0.06576592628969985,-0.6930805097254553,0.44303477605405855,-0.2609563355332265,0.2224334357534765
3,643
Parkinsonism
9
31
2.699325
0.006948
Q99720,P07602,O75569,O96008,O75787,Q14203,Q9Y4W6,Q96RR1,P05067
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,69,350,500,296,415,608,319,29
1078,350,296,500,703,29,69,591,2225,1713,754,1301,2242,2349,1984,2721,955,1895,1992,415,963,1827,2624,1675,319,3177,2,1064,2562,1690,608
0.2224334357534765,0.8756881681175116,0.9973494401983068,0.6298028841948623,0.44303477605405855,3.6353042018995785,2.427791890653298,0.5366787829519797,-0.22824695247054547,-0.03347806686168351,0.4117022638315761,0.12695555655645674,-0.22824695247054547,-0.2609563355332265,-0.13054795621506413,-0.42560918711049844,0.2857692407025649,-0.098122333905974,-0.13054795621506413,0.7531817696547146,0.2857692407025649,-0.06576592628969985,-0.3595238272390506,-0.0012581004565036626,0.9670119136618348,-0.726880811724572,8.21990109917503,0.25413257026133235,-0.3265940252928932,-0.0012581004565036626,0.5366787829519797
3,643
Peripheral demyelination
7
19
2.695275
0.007033
Q9NR77,P20700,P03886,P07602,P00846,O43681,P07196
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,310,62,69,74,118,125
118,74,62,2967,125,69,591,1878,310,1882,1155,3471,365,3091,32,1357,1064,1272,1279
1.7982903969638317,2.371337868662573,2.512197372488192,-0.5921770650124923,1.7400910153055076,2.427791890653298,0.5366787829519797,-0.098122333905974,0.9670119136618348,-0.098122333905974,0.19067127264620573,-1.174345720866778,0.845141841466991,-0.6593637349435877,3.6085359292973544,0.12695555655645674,0.25413257026133235,0.15884550726049723,0.15884550726049723
3,643
Endocytosis
35
139
2.68799
0.007188
Q14108,Q08380,O15118,Q8WTV0,P84095,Q5KU26,O14976,O00291,Q5VW38,P05067,P35579,P11717,P20645,Q06481,P02786,Q96ED9,Q9BZG1,Q14457,Q9NZM3,P50897,Q96RU3,Q13464,P51790,P30533,Q9NPF0,P41440,Q9H223,Q14185,Q15075,Q9Y5X1,O15260,Q99523,P57105,O75955,Q9NUN5
Processes and pathways
GO Biological process
msigdb_gobp
255,254,252,8,139,396,392,390,23,29,280,154,37,39,409,179,448,189,336,72,204,328,459,457,492,90,490,94,354,107,108,114,238,249,123
1206,390,1605,834,2322,3610,392,252,108,2860,588,1367,1078,249,2798,2328,3617,1787,409,29,3218,1012,3191,1702,1703,3572,1704,154,941,3024,942,1084,1794,1879,2578,37,3322,1711,3197,457,3520,280,90,655,1155,72,1300,2156,459,476,2348,238,1723,596,3571,1809,3077,1557,1389,1156,2251,139,3079,952,2813,39,955,3270,254,540,328,2596,1030,3348,255,2267,94,1402,189,2088,2089,2530,354,2269,1166,2727,3083,3042,1246,396,2093,23,3305,2946,1494,1411,1329,1915,3355,3597,8,2377,1050,3518,179,204,114,2687,1676,448,490,3003,1937,492,2554,123,3313,2307,336,872,1944,2957,3604,2401,3098,3063,2958,1854,3609,1595,3285,1596,743,1436,1204,107,2407,1525,583
0.15884550726049723,0.7838890695289682,-0.0012581004565036626,0.34885740302862467,-0.2609563355332265,-2.1540615170130093,0.7838890695289682,1.08805639508316,1.914184390727662,-0.525313577596298,0.5366787829519797,0.09500082791205905,0.2224334357534765,1.118191455601226,-0.4920008457387619,-0.2609563355332265,-2.342454069604444,-0.06576592628969985,0.7531817696547146,3.6353042018995785,-0.7947358122572576,0.25413257026133235,-0.7607655898218467,-0.03347806686168351,-0.03347806686168351,-1.6016175956969314,-0.03347806686168351,1.5350292358486646,0.2857692407025649,-0.6257295573052645,0.2857692407025649,0.2224334357534765,-0.06576592628969985,-0.098122333905974,-0.3595238272390506,3.284999162596966,-0.8971691305719629,-0.03347806686168351,-0.7607655898218467,0.6916031594494587,-1.315246174406957,1.027635769907882,2.058127752852981,0.47430803058067816,0.19067127264620573,2.399583395405736,0.12695555655645674,-0.19560956934146895,0.6916031594494587,0.6607309570482511,-0.2609563355332265,1.1482768495977804,-0.03347806686168351,0.5366787829519797,-1.5654960467228805,-0.06576592628969985,-0.6593637349435877,0.030894617027511038,0.09500082791205905,0.19067127264620573,-0.22824695247054547,1.623176179314646,-0.6593637349435877,0.2857692407025649,-0.4920008457387619,3.257840018273795,0.2857692407025649,-0.8287924672030076,1.08805639508316,0.5988184783374502,0.9366227945511973,-0.3595238272390506,0.25413257026133235,-0.931491220478586,1.08805639508316,-0.22824695247054547,2.0006717808585845,0.09500082791205905,1.387215394486587,-0.16304347134508207,-0.16304347134508207,-0.3265940252928932,0.8756881681175116,-0.22824695247054547,0.19067127264620573,-0.42560918711049844,-0.6593637349435877,-0.6257295573052645,0.15884550726049723,0.7838890695289682,-0.16304347134508207,4.295431147653506,-0.8629365633590367,-0.5587053640309138,0.06298071889501843,0.09500082791205905,0.12695555655645674,-0.098122333905974,-0.931491220478586,-1.820239680626571,5.940175937290734,-0.2609563355332265,0.25413257026133235,-1.2798752825252815,1.446478167816503,1.327766595224347,1.8563207862044178,-0.3925286203228279,-0.0012581004565036626,0.7224199472328477,0.6607309570482511,-0.5921770650124923,-0.098122333905974,0.6607309570482511,-0.3265940252928932,1.7692119702003737,-0.8629365633590367,-0.22824695247054547,0.9366227945511973,0.34885740302862467,-0.098122333905974,-0.5587053640309138,-1.8938214246167355,-0.2609563355332265,-0.6593637349435877,-0.6257295573052645,-0.5587053640309138,-0.06576592628969985,-2.042021033479733,0.030894617027511038,-0.8287924672030076,0.030894617027511038,0.44303477605405855,0.09500082791205905,0.19067127264620573,1.943054324684516,-0.2609563355332265,0.06298071889501843,0.5677772700633923
3,643
Abnormal muscle fiber morphology
22
75
2.676117
0.007448
Q99720,P51114,O96008,P02545,P06753,P05067,P13807,O60313,Q70HW3,O43676,Q7Z406,O95831,Q9BPX6,Q96RR1,Q13049,P00403,P03886,P23786,P00846,Q7LG56,Q9H9S5,P07196
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,504,500,265,394,29,533,529,285,163,300,47,320,319,188,559,62,200,74,464,347,125
2408,2049,1000,163,1776,529,2136,3404,2647,47,500,2705,559,74,265,62,2967,2922,29,394,125,2923,1376,3257,2331,533,2927,944,200,753,754,2662,890,2432,849,1155,504,3607,2073,1022,2242,2349,1809,1989,2358,188,959,2087,2529,1096,807,3043,285,464,2606,300,3047,2898,2538,2734,976,1675,319,2,320,1581,3181,733,347,2305,2789,2960,608,1604,1068
-0.29373844618932715,-0.16304347134508207,0.25413257026133235,1.5055575321040489,-0.06576592628969985,0.5988184783374502,-0.19560956934146895,-1.0350054838275398,-0.3925286203228279,3.0119856905575273,0.6298028841948623,-0.42560918711049844,0.5677772700633923,2.371337868662573,1.0578712931665288,2.512197372488192,-0.5921770650124923,-0.5587053640309138,3.6353042018995785,0.7838890695289682,1.7400910153055076,-0.5587053640309138,0.09500082791205905,-0.8287924672030076,-0.2609563355332265,0.5988184783374502,-0.5587053640309138,0.2857692407025649,1.327766595224347,0.4117022638315761,0.4117022638315761,-0.3925286203228279,0.31734400267200297,-0.29373844618932715,0.34885740302862467,0.19067127264620573,0.6298028841948623,-2.042021033479733,-0.16304347134508207,0.25413257026133235,-0.22824695247054547,-0.2609563355332265,-0.06576592628969985,-0.13054795621506413,-0.2609563355332265,1.387215394486587,0.2857692407025649,-0.16304347134508207,-0.3265940252928932,0.2224334357534765,0.3803099800917596,-0.6257295573052645,1.027635769907882,0.6916031594494587,-0.3595238272390506,0.9973494401983068,-0.6257295573052645,-0.525313577596298,-0.3265940252928932,-0.42560918711049844,0.2857692407025649,-0.0012581004565036626,0.9670119136618348,8.21990109917503,0.9670119136618348,0.030894617027511038,-0.726880811724572,0.44303477605405855,0.9061816816409076,-0.22824695247054547,-0.4587663248239629,-0.5587053640309138,0.5366787829519797,0.030894617027511038,0.25413257026133235
3,643
Positive regulation of immune effector process
16
43
2.654072
0.007953
Q9NUQ9,Q9BY67,Q06481,P02786,Q7Z434,P51809,P30511,P14174,Q01650,O15400,O95219,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0
Processes and pathways
GO Biological process
msigdb_gobp
102,304,39,409,420,476,138,15,143,586,235,590,87,429,522,227
586,2502,2860,2796,235,87,1872,409,2508,590,2509,653,3256,1082,15,1878,138,2229,3297,1548,476,143,39,1727,2526,2532,2535,969,420,2178,2377,1923,914,1928,3235,304,522,638,2394,227,102,429,3098
0.5366787829519797,-0.3265940252928932,-0.525313577596298,-0.4920008457387619,1.1482768495977804,2.11542427763213,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,-0.3265940252928932,0.47430803058067816,-0.8287924672030076,0.2224334357534765,4.964849362308119,-0.098122333905974,1.623176179314646,-0.22824695247054547,-0.8629365633590367,0.030894617027511038,0.6607309570482511,1.5938382520831849,3.257840018273795,-0.03347806686168351,-0.3265940252928932,-0.3265940252928932,-0.3265940252928932,0.2857692407025649,0.7531817696547146,-0.19560956934146895,-0.2609563355332265,-0.098122333905974,0.31734400267200297,-0.098122333905974,-0.7947358122572576,0.9973494401983068,0.6298028841948623,0.5055225334229401,-0.2609563355332265,1.2083001127798034,1.9718833674139287,0.7531817696547146,-0.6593637349435877
3,643
Anion transmembrane transport
22
50
2.65383
0.007958
Q86VD7,Q14728,Q01650,Q9HC21,Q9Y619,Q9Y666,Q9UHG3,P21796,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,Q15758,P30825,P55011,Q9H2D1,P45880,P51790,P51798,P41440,Q9Y6M7
Processes and pathways
GO Biological process
msigdb_gobp
256,624,143,553,693,694,430,34,152,306,577,44,573,662,54,440,733,78,459,460,90,361
1003,2754,2219,1450,3068,152,1962,1873,3218,1374,704,2331,1145,34,54,2342,90,78,459,3607,460,2073,44,440,2812,143,2771,2672,624,1317,662,3042,256,1177,573,2829,2906,577,733,1057,553,1844,306,430,924,2205,2640,693,694,361
0.25413257026133235,-0.4587663248239629,-0.22824695247054547,0.06298071889501843,-0.6593637349435877,1.5350292358486646,-0.13054795621506413,-0.098122333905974,-0.7947358122572576,0.09500082791205905,0.44303477605405855,-0.2609563355332265,0.19067127264620573,3.528055524230381,2.707887319665007,-0.2609563355332265,2.058127752852981,2.286376867508823,0.6916031594494587,-2.042021033479733,0.6916031594494587,-0.16304347134508207,3.1215736355280526,0.7224199472328477,-0.4920008457387619,1.5938382520831849,-0.4587663248239629,-0.3925286203228279,0.5055225334229401,0.12695555655645674,0.47430803058067816,-0.6257295573052645,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.4920008457387619,-0.525313577596298,0.5677772700633923,0.44303477605405855,0.25413257026133235,0.5988184783374502,-0.06576592628969985,0.9973494401983068,0.7531817696547146,0.31734400267200297,-0.19560956934146895,-0.3595238272390506,0.47430803058067816,0.47430803058067816,0.8756881681175116
3,643
Inability to walk
14
91
2.646675
0.008129
Q9NR77,P11166,Q99720,Q96N66,Q7RTS9,P00846,O75787,Q71SY5,Q9H9S5,O75503,Q96RR1,Q96CU9,P07196,Q9GZY8
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,279,2,358,11,74,296,144,347,24,319,92,125,130
1605,2049,2499,746,2212,2216,2136,24,296,2417,1869,791,2653,74,125,1874,3320,279,2331,591,1878,2225,1796,2339,844,1968,2972,753,754,1973,2431,2661,3033,1975,1882,1301,3441,2241,1387,797,3158,1809,2079,2168,1562,2885,3473,2529,899,1317,963,1165,666,1825,2729,144,1409,464,11,2606,1323,2895,544,673,860,812,2012,813,2180,2381,2182,92,3518,358,401,1675,319,2020,3178,2,2549,3181,130,1936,347,32,1197,3243,1946,2207,1068
-0.0012581004565036626,-0.16304347134508207,-0.3265940252928932,0.4117022638315761,-0.22824695247054547,-0.22824695247054547,-0.19560956934146895,4.11230346222967,0.9973494401983068,-0.29373844618932715,-0.098122333905974,0.3803099800917596,-0.3925286203228279,2.371337868662573,1.7400910153055076,-0.098122333905974,-0.8971691305719629,1.027635769907882,-0.2609563355332265,0.5366787829519797,-0.098122333905974,-0.22824695247054547,-0.06576592628969985,-0.2609563355332265,0.34885740302862467,-0.13054795621506413,-0.5921770650124923,0.4117022638315761,0.4117022638315761,-0.13054795621506413,-0.29373844618932715,-0.3925286203228279,-0.6257295573052645,-0.13054795621506413,-0.098122333905974,0.12695555655645674,-1.104482929673742,-0.22824695247054547,0.09500082791205905,0.3803099800917596,-0.726880811724572,-0.06576592628969985,-0.16304347134508207,-0.19560956934146895,0.030894617027511038,-0.525313577596298,-1.174345720866778,-0.3265940252928932,0.31734400267200297,0.12695555655645674,0.2857692407025649,0.19067127264620573,0.47430803058067816,-0.06576592628969985,-0.42560918711049844,1.5938382520831849,0.09500082791205905,0.6916031594494587,5.543953911878619,-0.3595238272390506,0.12695555655645674,-0.525313577596298,0.5988184783374502,0.47430803058067816,0.34885740302862467,0.3803099800917596,-0.13054795621506413,0.3803099800917596,-0.19560956934146895,-0.2609563355332265,-0.19560956934146895,2.0294198239892403,-1.2798752825252815,0.8756881681175116,0.7838890695289682,-0.0012581004565036626,0.9670119136618348,-0.13054795621506413,-0.726880811724572,8.21990109917503,-0.3265940252928932,-0.726880811724572,1.7109272480905777,-0.098122333905974,0.9061816816409076,3.6085359292973544,0.19067127264620573,-0.7947358122572576,-0.098122333905974,-0.19560956934146895,0.25413257026133235
3,643
Aplasia hypoplasia involving the vertebral column
6
17
2.63626
0.008383
P16278,P04066,Q7RTS9,O95831,Q14739,Q96HY6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
155,228,11,47,416,384
1210,2412,47,228,455,1377,155,707,1973,3297,1893,416,1566,1905,11,974,384
0.15884550726049723,-0.29373844618932715,3.0119856905575273,1.1783129469800828,0.6916031594494587,0.09500082791205905,1.5350292358486646,0.44303477605405855,-0.13054795621506413,-0.8629365633590367,-0.098122333905974,0.7531817696547146,0.030894617027511038,-0.098122333905974,5.543953911878619,0.2857692407025649,0.8145422833591529
3,643
Anion transmembrane transporter activity
25
57
2.632373
0.008479
Q86VD7,Q14728,Q01650,Q9H813,Q9HC21,Q9Y619,Q9Y666,P11166,P21796,O00400,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,Q15758,P30825,P55011,Q9H2D1,P45880,P51790,P51798,P41440,Q9Y6M7,O43681
Functions
GO Molecular function
msigdb_gomf
256,624,143,150,553,693,694,279,34,646,152,306,577,44,573,662,54,440,733,78,459,460,90,361,118
3065,646,2793,1003,118,2754,1450,152,1962,1873,704,1144,279,2331,1145,34,54,2342,90,78,459,3607,460,2073,44,440,143,2771,624,963,662,3042,2274,1657,2366,3456,256,1177,573,2829,2906,2907,1262,2292,577,2841,733,150,1057,553,306,924,2205,693,694,3315,361
-0.6593637349435877,0.47430803058067816,-0.4920008457387619,0.25413257026133235,1.7982903969638317,-0.4587663248239629,0.06298071889501843,1.5350292358486646,-0.13054795621506413,-0.098122333905974,0.44303477605405855,0.19067127264620573,1.027635769907882,-0.2609563355332265,0.19067127264620573,3.528055524230381,2.707887319665007,-0.2609563355332265,2.058127752852981,2.286376867508823,0.6916031594494587,-2.042021033479733,0.6916031594494587,-0.16304347134508207,3.1215736355280526,0.7224199472328477,1.5938382520831849,-0.4587663248239629,0.5055225334229401,0.2857692407025649,0.47430803058067816,-0.6257295573052645,-0.22824695247054547,-0.0012581004565036626,-0.2609563355332265,-1.1393655482262741,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.4920008457387619,-0.525313577596298,-0.525313577596298,0.15884550726049723,-0.22824695247054547,0.5677772700633923,-0.4920008457387619,0.44303477605405855,1.5644560394229112,0.25413257026133235,0.5988184783374502,0.9973494401983068,0.31734400267200297,-0.19560956934146895,0.47430803058067816,0.47430803058067816,-0.8629365633590367,0.8756881681175116
3,643
Positive regulation of cell activation
17
47
2.631193
0.008509
P23396,Q9NUQ9,Q9HCL2,Q15046,P04439,P51809,P02786,P30511,P14174,P12956,O95219,P30825,Q9NPF0,P00813,O96028,Q9NRA0,P31749
Processes and pathways
GO Biological process
msigdb_gobp
437,102,5,566,590,476,409,138,15,83,235,54,492,56,87,227,592
1952,2792,2215,2860,235,87,2757,56,409,2508,590,1081,3256,1082,83,15,3629,437,138,54,592,1547,1548,3440,476,1632,1390,1815,1395,1727,2526,1315,566,3621,1100,2535,969,2015,2619,914,1928,5,492,638,227,102,2788
-0.13054795621506413,-0.4920008457387619,-0.22824695247054547,-0.525313577596298,1.1482768495977804,2.11542427763213,-0.4587663248239629,2.6800374279695216,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.2224334357534765,-0.8287924672030076,0.2224334357534765,2.172563346869744,4.964849362308119,-2.997816021189173,0.7224199472328477,1.623176179314646,2.707887319665007,0.5366787829519797,0.030894617027511038,0.030894617027511038,-1.104482929673742,0.6607309570482511,-0.0012581004565036626,0.09500082791205905,-0.06576592628969985,0.09500082791205905,-0.03347806686168351,-0.3265940252928932,0.12695555655645674,0.5677772700633923,-2.4183808791889665,0.2224334357534765,-0.3265940252928932,0.2857692407025649,-0.13054795621506413,-0.3595238272390506,0.31734400267200297,-0.098122333905974,6.233993929662534,0.6607309570482511,0.5055225334229401,1.2083001127798034,1.9718833674139287,-0.4587663248239629
3,643
Cytokine production
25
112
2.61964
0.008802
Q9HCL2,P30511,P14174,Q01650,P14373,Q9NY93,P05067,P19474,Q06481,Q9BY67,Q7Z434,O75787,O75116,Q9Y6M1,Q13049,P23396,Q8IV08,Q8WXW3,P78536,P41440,Q9NRA0,Q9NUQ9,P17655,Q01082,O75955
Processes and pathways
GO Biological process
msigdb_gobp
5,138,15,143,395,429,29,36,39,304,420,296,293,324,188,437,73,468,216,90,227,102,473,365,249
1527,1209,1210,1001,2502,2574,1216,2794,293,3216,296,249,1698,2757,1872,703,2508,2863,590,29,1012,1789,1457,1081,653,1792,2511,3256,1704,15,395,941,473,1878,36,2225,1015,437,1148,616,2928,138,3615,3407,3520,2229,2764,1296,1547,90,756,709,3156,795,1557,1156,216,3038,2881,365,143,800,1815,39,1310,1394,1395,188,1092,2672,2267,1038,1097,1098,420,73,2609,2828,468,2178,1749,2100,1834,978,1923,2621,1674,863,3176,3177,3053,919,3002,304,3479,522,5,2394,227,989,102,429,828,1358,3098,2308,1689,3556,1204,1951,1443,324
0.030894617027511038,0.15884550726049723,0.15884550726049723,0.25413257026133235,-0.3265940252928932,-0.3595238272390506,0.15884550726049723,-0.4920008457387619,0.9973494401983068,-0.7947358122572576,0.9973494401983068,1.118191455601226,-0.03347806686168351,-0.4587663248239629,-0.098122333905974,0.44303477605405855,-0.3265940252928932,-0.525313577596298,0.5366787829519797,3.6353042018995785,0.25413257026133235,-0.06576592628969985,0.06298071889501843,0.2224334357534765,0.47430803058067816,-0.06576592628969985,-0.3265940252928932,-0.8287924672030076,-0.03347806686168351,4.964849362308119,0.7838890695289682,0.2857692407025649,0.6607309570482511,-0.098122333905974,3.3662912544280115,-0.22824695247054547,0.25413257026133235,0.7224199472328477,0.19067127264620573,0.5055225334229401,-0.5587053640309138,1.623176179314646,-2.2291720974867153,-1.0350054838275398,-1.315246174406957,-0.22824695247054547,-0.4587663248239629,0.12695555655645674,0.030894617027511038,2.058127752852981,0.4117022638315761,0.44303477605405855,-0.726880811724572,0.3803099800917596,0.030894617027511038,0.19067127264620573,1.2382387072449188,-0.6257295573052645,-0.525313577596298,0.845141841466991,1.5938382520831849,0.3803099800917596,-0.06576592628969985,3.257840018273795,0.12695555655645674,0.09500082791205905,0.09500082791205905,1.387215394486587,0.2224334357534765,-0.3925286203228279,-0.22824695247054547,0.25413257026133235,0.2224334357534765,0.2224334357534765,0.7531817696547146,2.399583395405736,-0.3595238272390506,-0.4920008457387619,0.6916031594494587,-0.19560956934146895,-0.03347806686168351,-0.16304347134508207,-0.06576592628969985,0.2857692407025649,-0.098122333905974,-0.3595238272390506,-0.0012581004565036626,0.34885740302862467,-0.726880811724572,-0.726880811724572,-0.6257295573052645,0.31734400267200297,-0.5921770650124923,0.9973494401983068,-1.174345720866778,0.6298028841948623,6.233993929662534,-0.2609563355332265,1.2083001127798034,0.2857692407025649,1.9718833674139287,0.7531817696547146,0.3803099800917596,0.12695555655645674,-0.6593637349435877,-0.22824695247054547,-0.0012581004565036626,-1.4576838354723742,0.19067127264620573,-0.098122333905974,0.09500082791205905,0.9670119136618348
3,643
Distal muscle weakness
14
70
2.616394
0.008886
Q9NR77,Q99720,Q7Z406,Q8TD16,P00846,Q14203,O95831,P02545,Q71SY5,P06753,P39210,P41440,P07196,Q00796
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,2,300,272,74,415,47,265,144,394,267,90,125,156
2049,746,2212,3404,2417,791,1782,47,74,265,394,125,2142,1376,3257,1221,1878,2927,944,1971,754,1544,2711,267,2232,2662,90,890,2432,1800,1155,2156,2073,2242,2716,2349,2880,3471,156,2358,1992,415,2087,2529,1165,2363,3502,627,668,1825,2729,2946,144,464,300,3047,3393,272,2830,2622,1675,1053,2,577,32,1274,1767,608,1604,1068
-0.16304347134508207,0.4117022638315761,-0.22824695247054547,-1.0350054838275398,-0.29373844618932715,0.3803099800917596,-0.06576592628969985,3.0119856905575273,2.371337868662573,1.0578712931665288,0.7838890695289682,1.7400910153055076,-0.19560956934146895,0.09500082791205905,-0.8287924672030076,0.15884550726049723,-0.098122333905974,-0.5587053640309138,0.2857692407025649,-0.13054795621506413,0.4117022638315761,0.030894617027511038,-0.42560918711049844,1.0578712931665288,-0.22824695247054547,-0.3925286203228279,2.058127752852981,0.31734400267200297,-0.29373844618932715,-0.06576592628969985,0.19067127264620573,-0.19560956934146895,-0.16304347134508207,-0.22824695247054547,-0.42560918711049844,-0.2609563355332265,-0.525313577596298,-1.174345720866778,1.5350292358486646,-0.2609563355332265,-0.13054795621506413,0.7531817696547146,-0.16304347134508207,-0.3265940252928932,0.19067127264620573,-0.2609563355332265,-1.244601121096576,0.5055225334229401,0.47430803058067816,-0.06576592628969985,-0.42560918711049844,-0.5587053640309138,1.5938382520831849,0.6916031594494587,0.9973494401983068,-0.6257295573052645,-1.0004082879139022,1.0578712931665288,-0.4920008457387619,-0.3595238272390506,-0.0012581004565036626,0.25413257026133235,8.21990109917503,0.5677772700633923,3.6085359292973544,0.15884550726049723,-0.03347806686168351,0.5366787829519797,0.030894617027511038,0.25413257026133235
3,643
Cell adhesion
14
41
2.61447
0.008937
P35579,P07942,P35580,Q08380,P35221,Q9BY67,Q9BQT9,Q96F07,Q92797,P10586,O00192,Q9BX67,P00813,P05067
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
280,126,222,254,534,304,275,344,149,119,389,488,56,29
389,789,1076,1959,56,3149,29,3218,1012,126,119,3257,3468,942,1620,843,534,708,280,222,1633,2162,2259,254,1395,1993,1031,1033,1315,1996,2271,855,149,1049,344,574,275,488,304,1587,1443
0.7838890695289682,0.3803099800917596,0.2224334357534765,-0.13054795621506413,2.6800374279695216,-0.726880811724572,3.6353042018995785,-0.7947358122572576,0.25413257026133235,1.7109272480905777,1.7982903969638317,-0.8287924672030076,-1.174345720866778,0.2857692407025649,-0.0012581004565036626,0.34885740302862467,0.5988184783374502,0.44303477605405855,1.027635769907882,1.2083001127798034,-0.0012581004565036626,-0.19560956934146895,-0.22824695247054547,1.08805639508316,0.09500082791205905,-0.13054795621506413,0.25413257026133235,0.25413257026133235,0.12695555655645674,-0.13054795621506413,-0.22824695247054547,0.34885740302862467,1.5644560394229112,0.25413257026133235,0.9061816816409076,0.5677772700633923,1.0578712931665288,0.6607309570482511,0.9973494401983068,0.030894617027511038,0.09500082791205905
3,643
Lipid binding
30
157
2.60825
0.009101
Q14108,O15118,Q8WTV0,O94788,O14773,Q9UM22,O00291,Q8NCC3,P11717,P21796,Q06481,P28070,A6NIH7,P07602,P50897,O15173,Q96RU3,P45880,Q9Y4G8,O15254,Q9H4L5,Q15075,P61916,Q9Y5X1,Q53T59,Q01082,Q9NS86,O95219,Q9NWW5,Q6ZVM7
Functions
GO Molecular function
msigdb_gomf
255,252,8,9,391,22,390,28,154,34,39,164,46,69,72,199,204,78,81,89,100,354,351,107,366,365,117,235,251,381
1206,46,932,390,1605,834,2322,453,3510,391,1774,2571,252,199,89,3101,2216,2963,1004,529,1213,588,2700,1367,3144,9,2417,2798,235,2507,1787,703,2508,2054,3191,69,1080,3106,1081,3256,2144,3023,2800,154,1378,3591,560,34,1797,1293,2762,164,3196,1381,3615,592,3261,1225,2431,847,78,3035,709,2934,72,3265,3157,1804,1302,3558,2159,2349,3515,2244,351,3120,2163,1392,365,39,3411,507,540,2596,2528,1030,255,2088,3301,1163,2530,964,354,902,366,666,1572,381,2537,1494,1911,2372,1410,2948,28,2900,3477,8,515,1921,3308,1049,1050,980,575,204,1263,3235,3179,1676,2999,3630,2688,2114,1347,984,3212,1424,549,2479,3213,100,2116,2482,117,2695,251,1432,1064,1944,3008,2308,1854,22,3285,1596,1855,2564,3585,3493,1437,2206,81,107,433,2407,1525
0.15884550726049723,3.0942250631129866,0.2857692407025649,0.7838890695289682,-0.0012581004565036626,0.34885740302862467,-0.2609563355332265,0.6916031594494587,-1.2798752825252815,0.7838890695289682,-0.06576592628969985,-0.3595238272390506,1.08805639508316,1.327766595224347,2.0867958206204555,-0.6930805097254553,-0.22824695247054547,-0.5921770650124923,0.25413257026133235,0.5988184783374502,0.15884550726049723,0.5366787829519797,-0.42560918711049844,0.09500082791205905,-0.726880811724572,5.816916168706705,-0.29373844618932715,-0.4920008457387619,1.1482768495977804,-0.3265940252928932,-0.06576592628969985,0.44303477605405855,-0.3265940252928932,-0.16304347134508207,-0.7607655898218467,2.427791890653298,0.2224334357534765,-0.6930805097254553,0.2224334357534765,-0.8287924672030076,-0.19560956934146895,-0.6257295573052645,-0.4920008457387619,1.5350292358486646,0.09500082791205905,-1.7470088834303552,0.5677772700633923,3.528055524230381,-0.06576592628969985,0.12695555655645674,-0.4587663248239629,1.5055575321040489,-0.7607655898218467,0.09500082791205905,-2.2291720974867153,0.5366787829519797,-0.8287924672030076,0.15884550726049723,-0.29373844618932715,0.34885740302862467,2.286376867508823,-0.6257295573052645,0.44303477605405855,-0.5587053640309138,2.399583395405736,-0.8287924672030076,-0.726880811724572,-0.06576592628969985,0.12695555655645674,-1.4935285643358234,-0.19560956934146895,-0.2609563355332265,-1.2798752825252815,-0.22824695247054547,0.8756881681175116,-0.6930805097254553,-0.19560956934146895,0.09500082791205905,0.845141841466991,3.257840018273795,-1.0350054838275398,0.6298028841948623,0.5988184783374502,-0.3595238272390506,-0.3265940252928932,0.25413257026133235,1.08805639508316,-0.16304347134508207,-0.8629365633590367,0.19067127264620573,-0.3265940252928932,0.2857692407025649,0.8756881681175116,0.31734400267200297,0.845141841466991,0.47430803058067816,0.030894617027511038,0.8145422833591529,-0.3265940252928932,0.06298071889501843,-0.098122333905974,-0.2609563355332265,0.09500082791205905,-0.5587053640309138,3.768713037747525,-0.525313577596298,-1.174345720866778,5.940175937290734,0.6298028841948623,-0.098122333905974,-0.8629365633590367,0.25413257026133235,0.25413257026133235,0.2857692407025649,0.5677772700633923,1.327766595224347,0.15884550726049723,-0.7947358122572576,-0.726880811724572,-0.0012581004565036626,-0.5921770650124923,-3.1552041982193537,-0.3925286203228279,-0.16304347134508207,0.12695555655645674,0.2857692407025649,-0.7607655898218467,0.09500082791205905,0.5988184783374502,-0.29373844618932715,-0.7607655898218467,1.9718833674139287,-0.16304347134508207,-0.29373844618932715,1.8273265764439528,-0.3925286203228279,1.118191455601226,0.09500082791205905,0.25413257026133235,-0.098122333905974,-0.5921770650124923,-0.22824695247054547,-0.06576592628969985,4.373525061543824,-0.8287924672030076,0.030894617027511038,-0.06576592628969985,-0.3265940252928932,-1.6741333670170677,-1.209424370050621,0.09500082791205905,-0.19560956934146895,2.2579809707838456,1.943054324684516,0.7531817696547146,-0.2609563355332265,0.06298071889501843
3,643
Dysphagia
39
144
2.597772
0.009383
Q05639,Q99720,Q01105,Q14108,O15344,O15118,Q9HD42,Q8IZA0,Q8N3U4,P06753,P05067,Q9NR77,O60313,Q9UHX1,Q8N0X7,P15586,Q14203,Q14739,Q96RR1,P29372,P03886,P20700,P55011,O95155,P07602,Q15233,P00846,Q7LG56,Q9Y4W6,P48735,P17480,P61916,O75569,O75306,Q14331,P42356,Q8NFF5,Q9UEY8,Q9GZY8
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
622,2,505,255,253,252,276,141,673,394,29,32,529,171,421,410,415,416,319,438,62,310,440,307,69,567,74,464,608,339,591,351,350,471,477,617,382,526,130
1605,1862,1210,2049,252,253,2504,529,1078,2136,471,3145,350,1284,881,2417,1869,307,2649,1782,3103,3147,74,1872,62,2967,703,2654,29,394,69,1080,1874,2142,1375,2058,3257,2512,2331,410,591,1707,1221,310,1796,1148,2339,2971,438,3260,753,754,2431,617,1882,890,339,1301,2073,2242,1088,1387,440,2349,797,1471,3158,3471,351,2252,1025,2590,1026,952,505,2721,622,2358,1309,955,3270,1992,3473,255,415,2087,477,899,416,964,1165,567,1096,2820,2454,1827,464,3047,1044,141,421,3088,673,2898,382,813,3091,2612,3518,2835,980,2624,1675,319,2736,3176,3178,2,3054,2549,2387,1054,3416,130,3418,1056,276,32,826,1850,1064,689,1852,1521,2913,526,1522,171,2562,928,1203,2312,1765,608
-0.0012581004565036626,-0.098122333905974,0.15884550726049723,-0.16304347134508207,1.08805639508316,1.08805639508316,-0.3265940252928932,0.5988184783374502,0.2224334357534765,-0.19560956934146895,0.6607309570482511,-0.726880811724572,0.8756881681175116,0.12695555655645674,0.31734400267200297,-0.29373844618932715,-0.098122333905974,0.9670119136618348,-0.3925286203228279,-0.06576592628969985,-0.6930805097254553,-0.726880811724572,2.371337868662573,-0.098122333905974,2.512197372488192,-0.5921770650124923,0.44303477605405855,-0.3925286203228279,3.6353042018995785,0.7838890695289682,2.427791890653298,0.2224334357534765,-0.098122333905974,-0.19560956934146895,0.09500082791205905,-0.16304347134508207,-0.8287924672030076,-0.3265940252928932,-0.2609563355332265,0.7531817696547146,0.5366787829519797,-0.03347806686168351,0.15884550726049723,0.9670119136618348,-0.06576592628969985,0.19067127264620573,-0.2609563355332265,-0.5921770650124923,0.7224199472328477,-0.8287924672030076,0.4117022638315761,0.4117022638315761,-0.29373844618932715,0.5055225334229401,-0.098122333905974,0.31734400267200297,0.9061816816409076,0.12695555655645674,-0.16304347134508207,-0.22824695247054547,0.2224334357534765,0.09500082791205905,0.7224199472328477,-0.2609563355332265,0.3803099800917596,0.06298071889501843,-0.726880811724572,-1.174345720866778,0.8756881681175116,-0.22824695247054547,0.25413257026133235,-0.3595238272390506,0.25413257026133235,0.2857692407025649,0.6298028841948623,-0.42560918711049844,0.5055225334229401,-0.2609563355332265,0.12695555655645674,0.2857692407025649,-0.8287924672030076,-0.13054795621506413,-1.174345720866778,1.08805639508316,0.7531817696547146,-0.16304347134508207,0.6607309570482511,0.31734400267200297,0.7531817696547146,0.2857692407025649,0.19067127264620573,0.5677772700633923,0.2224334357534765,-0.4920008457387619,-0.29373844618932715,-0.06576592628969985,0.6916031594494587,-0.6257295573052645,0.25413257026133235,1.623176179314646,0.7531817696547146,-0.6593637349435877,0.47430803058067816,-0.525313577596298,0.8145422833591529,0.3803099800917596,-0.6593637349435877,-0.3595238272390506,-1.2798752825252815,-0.4920008457387619,0.2857692407025649,-0.3595238272390506,-0.0012581004565036626,0.9670119136618348,-0.42560918711049844,-0.726880811724572,-0.726880811724572,8.21990109917503,-0.6257295573052645,-0.3265940252928932,-0.2609563355332265,0.25413257026133235,-1.0350054838275398,1.7109272480905777,-1.0350054838275398,0.25413257026133235,1.0578712931665288,3.6085359292973544,0.3803099800917596,-0.06576592628969985,0.25413257026133235,0.47430803058067816,-0.06576592628969985,0.06298071889501843,-0.525313577596298,0.6298028841948623,0.06298071889501843,1.5055575321040489,-0.3265940252928932,0.31734400267200297,0.19067127264620573,-0.22824695247054547,-0.03347806686168351,0.5366787829519797
3,643
Signaling receptor regulator activity
8
23
2.574595
0.010036
P49354,P22466,P43490,P14174,Q15375,P30533,Q9UMX5,P05067
Functions
GO Molecular function
msigdb_gomf
229,38,71,15,418,457,27,29
29,2509,1081,15,1084,38,616,457,71,229,2584,2521,3515,2433,3079,2082,2269,418,1044,677,492,27,2405
3.6353042018995785,-0.3265940252928932,0.2224334357534765,4.964849362308119,0.2224334357534765,3.257840018273795,0.5055225334229401,0.6916031594494587,2.399583395405736,1.1783129469800828,-0.3595238272390506,-0.3265940252928932,-1.2798752825252815,-0.29373844618932715,-0.6593637349435877,-0.16304347134508207,-0.22824695247054547,0.7531817696547146,0.25413257026133235,0.47430803058067816,0.6607309570482511,3.795309279757627,-0.2609563355332265
3,643
Exopeptidase activity
11
34
2.572909
0.010085
Q9H3G5,Q9HB40,P42785,Q9UIQ6,Q9NZ08,O75976,O14773,Q9NQH7,O75844,P10619,P55786
Functions
GO Molecular function
msigdb_gomf
359,35,4,42,245,206,391,386,248,59,31
391,248,206,409,2222,59,3108,3323,2659,1544,4,3298,1554,1632,31,2883,3347,2773,2776,1322,2005,1417,913,3395,1188,3179,359,3554,35,386,3241,3137,245,42
0.7838890695289682,1.118191455601226,1.2979715997804608,0.7531817696547146,-0.22824695247054547,2.5402599154147643,-0.6930805097254553,-0.8971691305719629,-0.3925286203228279,0.030894617027511038,6.233993929662534,-0.8629365633590367,0.030894617027511038,-0.0012581004565036626,3.6085359292973544,-0.525313577596298,-0.931491220478586,-0.4587663248239629,-0.4587663248239629,0.12695555655645674,-0.13054795621506413,0.09500082791205905,0.31734400267200297,-1.0004082879139022,0.19067127264620573,-0.726880811724572,0.8756881681175116,-1.4576838354723742,3.447308651903207,0.8145422833591529,-0.7947358122572576,-0.6930805097254553,1.1482768495977804,3.2306497156014906
3,643
Azurophil granule membrane
7
25
2.572345
0.010101
P42785,P07602,O15260,Q07065,P15291,P10253,Q9NQX7
Localization
GO Cellular component
msigdb_gocc
4,69,108,173,112,266,122
108,2700,1078,1456,69,266,3219,1082,2332,112,563,3200,4,1300,476,173,2001,1916,317,3179,2115,122,2912,1064,1199
1.914184390727662,-0.42560918711049844,0.2224334357534765,0.06298071889501843,2.427791890653298,1.0578712931665288,-0.7947358122572576,0.2224334357534765,-0.2609563355332265,1.8563207862044178,0.5677772700633923,-0.7607655898218467,6.233993929662534,0.12695555655645674,0.6607309570482511,1.4760406150941263,-0.13054795621506413,-0.098122333905974,0.9670119136618348,-0.726880811724572,-0.16304347134508207,1.7692119702003737,-0.525313577596298,0.25413257026133235,0.19067127264620573
3,643
Nucleophile aminohydrolases, N-terminal [IPR029055]
6
17
2.556909
0.010561
P28070,P28074,P20618,P28072,Q99436,P49721
Sequence
InterPro Superfamily
interpro_homologous_superfamily
164,41,137,146,121,60
3142,1875,137,2762,1461,1621,2802,3222,164,146,41,2878,60,283,2525,2358,121
-0.726880811724572,-0.098122333905974,1.623176179314646,-0.4587663248239629,0.06298071889501843,-0.0012581004565036626,-0.4920008457387619,-0.7947358122572576,1.5055575321040489,1.5644560394229112,3.2306497156014906,-0.525313577596298,2.5402599154147643,1.027635769907882,-0.3265940252928932,-0.2609563355332265,1.7692119702003737
3,643
Supranuclear gaze palsy
7
20
2.543319
0.010981
Q99720,P07602,O15118,P61916,Q14203,Q96RR1,Q969N2
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,69,252,351,415,319,318
1862,1210,252,703,69,2655,3260,754,2242,2349,351,1992,415,318,1675,319,2,1064,2913,526
-0.098122333905974,0.15884550726049723,1.08805639508316,0.44303477605405855,2.427791890653298,-0.3925286203228279,-0.8287924672030076,0.4117022638315761,-0.22824695247054547,-0.2609563355332265,0.8756881681175116,-0.13054795621506413,0.7531817696547146,0.9670119136618348,-0.0012581004565036626,0.9670119136618348,8.21990109917503,0.25413257026133235,-0.525313577596298,0.6298028841948623
3,643
Neuron death
17
76
2.538717
0.011126
Q99720,Q01105,P50897,P17655,P30511,Q15392,Q13464,O95831,Q96A26,Q15375,Q92542,P31751,P07196,Q99538,Q969N2,Q9UMX5,P05067
Processes and pathways
GO Biological process
msigdb_gobp
2,505,72,473,138,45,328,47,243,418,317,364,125,520,318,27,29
1606,3495,2861,3068,881,885,47,703,3291,2863,1288,29,1010,2509,125,1457,2866,653,1791,1704,840,473,138,592,364,3520,708,1548,3155,2582,757,2236,1800,1801,72,1301,2584,1723,2806,3163,2251,2769,3079,505,2721,506,2168,328,2596,1401,1240,567,418,45,1902,2455,317,318,243,3332,1923,2624,3177,520,2,1056,2391,2631,779,2038,3569,1274,1594,27,1855,1768
-0.0012581004565036626,-1.244601121096576,-0.525313577596298,-0.6593637349435877,0.31734400267200297,0.31734400267200297,3.0119856905575273,0.44303477605405855,-0.8629365633590367,-0.525313577596298,0.12695555655645674,3.6353042018995785,0.25413257026133235,-0.3265940252928932,1.7400910153055076,0.06298071889501843,-0.525313577596298,0.47430803058067816,-0.06576592628969985,-0.03347806686168351,0.34885740302862467,0.6607309570482511,1.623176179314646,0.5366787829519797,0.845141841466991,-1.315246174406957,0.44303477605405855,0.030894617027511038,-0.726880811724572,-0.3595238272390506,0.4117022638315761,-0.22824695247054547,-0.06576592628969985,-0.06576592628969985,2.399583395405736,0.12695555655645674,-0.3595238272390506,-0.03347806686168351,-0.4920008457387619,-0.726880811724572,-0.22824695247054547,-0.4587663248239629,-0.6593637349435877,0.6298028841948623,-0.42560918711049844,0.6298028841948623,-0.19560956934146895,0.9366227945511973,-0.3595238272390506,0.09500082791205905,0.15884550726049723,0.5677772700633923,0.7531817696547146,3.1215736355280526,-0.098122333905974,-0.29373844618932715,0.9670119136618348,0.9670119136618348,1.1482768495977804,-0.8971691305719629,-0.098122333905974,-0.3595238272390506,-0.726880811724572,0.6298028841948623,8.21990109917503,0.25413257026133235,-0.2609563355332265,-0.3595238272390506,0.4117022638315761,-0.13054795621506413,-1.5294661704120023,0.15884550726049723,0.030894617027511038,3.795309279757627,-0.06576592628969985,-0.03347806686168351
3,643
Abnormal femoral neck morphology
16
43
2.535531
0.011228
P16278,O00754,P55011,P04066,Q8WVQ1,Q96L58,Q9Y487,Q7RTS9,O75718,O95831,P02545,O75431,O75530,O75844,P11274,Q96HY6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
155,435,440,228,423,303,43,11,295,47,265,213,86,248,338,384
834,435,2412,213,86,295,248,47,265,228,338,155,2337,2147,3197,707,2933,3117,2713,1802,3626,440,2434,900,806,1038,2364,11,423,2612,1048,1112,384,303,2185,3052,3096,524,2041,3012,43,1069,693
0.34885740302862467,0.7224199472328477,-0.29373844618932715,1.2382387072449188,2.11542427763213,0.9973494401983068,1.118191455601226,3.0119856905575273,1.0578712931665288,1.1783129469800828,0.9061816816409076,1.5350292358486646,-0.2609563355332265,-0.19560956934146895,-0.7607655898218467,0.44303477605405855,-0.5587053640309138,-0.6930805097254553,-0.42560918711049844,-0.06576592628969985,-2.919565762049335,0.7224199472328477,-0.29373844618932715,0.31734400267200297,0.3803099800917596,0.25413257026133235,-0.2609563355332265,5.543953911878619,0.7531817696547146,-0.3595238272390506,0.25413257026133235,0.2224334357534765,0.8145422833591529,0.9973494401983068,-0.19560956934146895,-0.6257295573052645,-0.6593637349435877,0.6298028841948623,-0.13054795621506413,-0.5921770650124923,3.2306497156014906,0.25413257026133235,0.47430803058067816
3,643
Response to oxygen levels
17
71
2.534997
0.011245
P11166,Q9Y487,P02786,P00846,P80404,P17655,P30519,O95831,P02545,O75116,O43707,Q96A26,P00813,O75592,P78536,Q14457,P55786
Processes and pathways
GO Biological process
msigdb_gobp
279,43,409,74,413,473,14,47,265,293,325,243,56,186,216,189,31
2916,3186,325,293,471,186,2966,3103,47,3148,56,74,265,409,2967,3291,1288,3149,3190,3150,653,279,2513,942,473,1221,1222,2148,14,2972,592,1973,2661,1086,2069,2236,1301,1721,31,2587,216,413,1989,2671,1240,189,661,2091,965,1903,1907,3275,1914,1330,1331,1749,243,1923,2833,3235,2292,3561,2631,1059,3481,784,2043,2562,43,1768,1603
-0.5587053640309138,-0.7607655898218467,0.9366227945511973,0.9973494401983068,0.6607309570482511,1.387215394486587,-0.5921770650124923,-0.6930805097254553,3.0119856905575273,-0.726880811724572,2.6800374279695216,2.371337868662573,1.0578712931665288,0.7531817696547146,-0.5921770650124923,-0.8629365633590367,0.12695555655645674,-0.726880811724572,-0.7607655898218467,-0.726880811724572,0.47430803058067816,1.027635769907882,-0.3265940252928932,0.2857692407025649,0.6607309570482511,0.15884550726049723,0.15884550726049723,-0.19560956934146895,5.1928477731586264,-0.5921770650124923,0.5366787829519797,-0.13054795621506413,-0.3925286203228279,0.2224334357534765,-0.16304347134508207,-0.22824695247054547,0.12695555655645674,-0.03347806686168351,3.6085359292973544,-0.3595238272390506,1.2382387072449188,0.7531817696547146,-0.13054795621506413,-0.3925286203228279,0.15884550726049723,1.387215394486587,0.47430803058067816,-0.16304347134508207,0.2857692407025649,-0.098122333905974,-0.098122333905974,-0.8287924672030076,-0.098122333905974,0.12695555655645674,0.12695555655645674,-0.03347806686168351,1.1482768495977804,-0.098122333905974,-0.4920008457387619,-0.7947358122572576,-0.22824695247054547,-1.4935285643358234,-0.3595238272390506,0.25413257026133235,-1.174345720866778,0.4117022638315761,-0.13054795621506413,-0.3265940252928932,3.2306497156014906,-0.03347806686168351,0.030894617027511038
3,643
Endocytic vesicle membrane
13
50
2.533421
0.011296
P11717,Q14108,P20645,Q06481,Q8WTV0,Q9Y487,P02786,Q13555,P30511,O43493,Q5KU26,Q93050,Q9BZG1
Localization
GO Cellular component
msigdb_gocc
154,255,37,39,8,43,409,105,138,142,396,82,448
1695,142,1449,2798,2328,3617,1872,409,590,532,1082,154,3591,2332,2578,37,2658,138,1155,2156,1552,476,2348,2805,1890,2587,2251,952,2257,1028,39,1727,105,3348,255,1036,902,1166,3124,396,767,970,8,82,1050,3234,448,3479,2041,43
-0.03347806686168351,1.5938382520831849,0.06298071889501843,-0.4920008457387619,-0.2609563355332265,-2.342454069604444,-0.098122333905974,0.7531817696547146,0.5366787829519797,0.5988184783374502,0.2224334357534765,1.5350292358486646,-1.7470088834303552,-0.2609563355332265,-0.3595238272390506,3.284999162596966,-0.3925286203228279,1.623176179314646,0.19067127264620573,-0.19560956934146895,0.030894617027511038,0.6607309570482511,-0.2609563355332265,-0.4920008457387619,-0.098122333905974,-0.3595238272390506,-0.22824695247054547,0.2857692407025649,-0.22824695247054547,0.25413257026133235,3.257840018273795,-0.03347806686168351,1.943054324684516,-0.931491220478586,1.08805639508316,0.25413257026133235,0.31734400267200297,0.19067127264620573,-0.6930805097254553,0.7838890695289682,0.4117022638315761,0.2857692407025649,5.940175937290734,2.2010744460285183,0.25413257026133235,-0.7947358122572576,0.7224199472328477,-1.174345720866778,-0.13054795621506413,3.2306497156014906
3,643
Impaired proprioception
17
48
2.525104
0.011566
Q9NR77,Q5THJ4,P20700,P41440,Q8IV08,Q8N0X7,P00846,Q9Y448,O75298,Q9H6K4,O14773,P54802,Q5TAQ9,Q96RR1,Q9Y619,P07196,Q00796
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,668,310,90,73,421,74,348,393,579,391,147,627,319,693,125,156
1770,646,391,1210,2571,2504,393,2417,791,74,2509,125,3256,1221,1878,310,1971,2662,90,2242,147,1387,2349,156,1989,955,801,1238,3328,2091,627,668,2729,2946,73,421,2012,1675,319,2112,1423,579,32,3519,2562,348,693,876
-0.06576592628969985,0.47430803058067816,0.7838890695289682,0.15884550726049723,-0.3595238272390506,-0.3265940252928932,0.7838890695289682,-0.29373844618932715,0.3803099800917596,2.371337868662573,-0.3265940252928932,1.7400910153055076,-0.8287924672030076,0.15884550726049723,-0.098122333905974,0.9670119136618348,-0.13054795621506413,-0.3925286203228279,2.058127752852981,-0.22824695247054547,1.5644560394229112,0.09500082791205905,-0.2609563355332265,1.5350292358486646,-0.13054795621506413,0.2857692407025649,0.3803099800917596,0.15884550726049723,-0.8971691305719629,-0.16304347134508207,0.5055225334229401,0.47430803058067816,-0.42560918711049844,-0.5587053640309138,2.399583395405736,0.7531817696547146,-0.13054795621506413,-0.0012581004565036626,0.9670119136618348,-0.16304347134508207,0.09500082791205905,0.5677772700633923,3.6085359292973544,-1.2798752825252815,-0.3265940252928932,0.9061816816409076,0.47430803058067816,0.34885740302862467
3,643
Immune effector process
25
84
2.522648
0.011647
Q92538,P30511,P14174,Q01650,Q9NY93,P05067,Q9UQ84,Q06481,Q9BY67,P02786,Q7Z434,P00813,P33176,Q15046,P04439,O96028,O15400,P78536,P11274,Q9NRA0,Q9NUQ9,P51809,Q9NQT5,O95219,Q9H2U1
Processes and pathways
GO Biological process
msigdb_gobp
515,138,15,143,429,29,33,39,304,409,420,56,312,566,590,87,586,216,338,227,102,476,638,235,522
1207,586,2502,2860,1217,2646,2796,235,87,3147,56,1872,409,2508,590,1288,29,2509,1701,1081,653,3256,1704,338,1082,3591,3513,15,1084,1878,138,2874,3520,312,2229,1385,3297,1296,1086,1548,2712,476,1553,1632,1233,2161,216,143,1893,2938,39,1310,1395,1727,2526,566,1165,2532,1404,2535,969,1737,420,2993,2178,515,2377,1923,681,914,1928,3235,304,3479,522,638,2394,227,102,3337,429,3098,1855,33
0.15884550726049723,0.5366787829519797,-0.3265940252928932,-0.525313577596298,0.15884550726049723,-0.3925286203228279,-0.4920008457387619,1.1482768495977804,2.11542427763213,-0.726880811724572,2.6800374279695216,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,0.12695555655645674,3.6353042018995785,-0.3265940252928932,-0.03347806686168351,0.2224334357534765,0.47430803058067816,-0.8287924672030076,-0.03347806686168351,0.9061816816409076,0.2224334357534765,-1.7470088834303552,-1.2798752825252815,4.964849362308119,0.2224334357534765,-0.098122333905974,1.623176179314646,-0.525313577596298,-1.315246174406957,0.9670119136618348,-0.22824695247054547,0.09500082791205905,-0.8629365633590367,0.12695555655645674,0.2224334357534765,0.030894617027511038,-0.42560918711049844,0.6607309570482511,0.030894617027511038,-0.0012581004565036626,0.15884550726049723,-0.19560956934146895,1.2382387072449188,1.5938382520831849,-0.098122333905974,-0.5587053640309138,3.257840018273795,0.12695555655645674,0.09500082791205905,-0.03347806686168351,-0.3265940252928932,0.5677772700633923,0.19067127264620573,-0.3265940252928932,0.09500082791205905,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.7531817696547146,-0.5921770650124923,-0.19560956934146895,0.6298028841948623,-0.2609563355332265,-0.098122333905974,0.47430803058067816,0.31734400267200297,-0.098122333905974,-0.7947358122572576,0.9973494401983068,-1.174345720866778,0.6298028841948623,0.5055225334229401,-0.2609563355332265,1.2083001127798034,1.9718833674139287,-0.8971691305719629,0.7531817696547146,-0.6593637349435877,-0.06576592628969985,3.6085359292973544
3,643
Clumsiness
7
18
2.515118
0.011899
Q9NR77,P07602,P06753,O14773,O43681,O75503,Q96RR1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,69,394,391,118,24,319
1770,435,391,1210,118,2504,24,394,69,753,3473,964,2452,2729,319,32,1064,2913
-0.06576592628969985,0.7224199472328477,0.7838890695289682,0.15884550726049723,1.7982903969638317,-0.3265940252928932,4.11230346222967,0.7838890695289682,2.427791890653298,0.4117022638315761,-1.174345720866778,0.2857692407025649,-0.29373844618932715,-0.42560918711049844,0.9670119136618348,3.6085359292973544,0.25413257026133235,-0.525313577596298
3,643
Regulation of blood pressure
6
22
2.510976
0.01204
Q9HB40,P42785,Q9UIQ6,Q9NZ08,P42892,P09493
Processes and pathways
GO Biological process
msigdb_gobp
35,4,42,245,53,215
296,3291,2054,215,653,1378,1015,2580,4,53,2519,1301,413,1095,2776,2612,519,3533,35,245,42,2407
0.9973494401983068,-0.8629365633590367,-0.16304347134508207,1.2382387072449188,0.47430803058067816,0.09500082791205905,0.25413257026133235,-0.3595238272390506,6.233993929662534,2.763483088965262,-0.3265940252928932,0.12695555655645674,0.7531817696547146,0.2224334357534765,-0.4587663248239629,-0.3595238272390506,0.6298028841948623,-1.3507131280591325,3.447308651903207,1.1482768495977804,3.2306497156014906,-0.2609563355332265
3,643
Endoplasmic reticulum lumen
16
69
2.509169
0.012102
Q02818,P07942,Q14257,Q06481,O00584,Q86UP2,Q8NBJ4,Q9NZ08,Q07065,O43493,Q9BTY2,O43681,Q9NWW5,P78536,Q8IXB1,P05067
Localization
GO Cellular component
msigdb_gocc
65,126,299,39,103,301,75,245,173,142,115,118,251,216,218,29
103,3610,2642,1956,142,118,2698,1958,295,881,1700,29,3150,126,3220,1704,3257,2656,1219,1706,2513,843,2516,3322,2658,1711,3197,2066,3030,457,1886,1632,3515,216,65,39,173,1238,1093,299,2941,1997,2448,3583,2728,1246,2776,2730,301,218,75,2826,3548,1663,1503,2950,1112,2833,2293,1581,115,3001,737,251,1942,245,3283,1768,372
1.943054324684516,-2.1540615170130093,-0.3925286203228279,-0.13054795621506413,1.5938382520831849,1.7982903969638317,-0.42560918711049844,-0.13054795621506413,0.9973494401983068,0.31734400267200297,-0.03347806686168351,3.6353042018995785,-0.726880811724572,1.7109272480905777,-0.7947358122572576,-0.03347806686168351,-0.8287924672030076,-0.3925286203228279,0.15884550726049723,-0.03347806686168351,-0.3265940252928932,0.34885740302862467,-0.3265940252928932,-0.8971691305719629,-0.3925286203228279,-0.03347806686168351,-0.7607655898218467,-0.16304347134508207,-0.6257295573052645,0.6916031594494587,-0.098122333905974,-0.0012581004565036626,-1.2798752825252815,1.2382387072449188,2.4840986629825825,3.257840018273795,1.4760406150941263,0.15884550726049723,0.2224334357534765,0.9973494401983068,-0.5587053640309138,-0.13054795621506413,-0.29373844618932715,-1.6741333670170677,-0.42560918711049844,0.15884550726049723,-0.4587663248239629,-0.42560918711049844,0.9973494401983068,1.2382387072449188,2.371337868662573,-0.4920008457387619,-1.421932600442622,-0.0012581004565036626,0.06298071889501843,-0.5587053640309138,0.2224334357534765,-0.4920008457387619,-0.22824695247054547,0.030894617027511038,1.8563207862044178,-0.5921770650124923,0.44303477605405855,1.118191455601226,-0.098122333905974,1.1482768495977804,-0.8287924672030076,-0.03347806686168351,0.845141841466991
3,643
Vesicle lumen
29
131
2.508809
0.012114
Q08380,P78371,P20618,P14174,Q8N2G8,P06280,P05067,P16278,O00231,Q8WVQ1,P15586,P00813,Q13813,P10619,O00754,P12814,O15078,Q8NBX0,Q13464,O43707,P12956,Q7L576,Q9NUQ9,P04066,O00584,P61916,Q9BTY2,O43681,Q99436
Localization
GO Cellular component
msigdb_gocc
254,378,137,15,398,153,29,155,278,423,410,56,315,59,435,308,194,331,328,325,83,340,102,228,103,351,115,118,121
278,3316,1135,2322,1209,103,435,611,194,1609,118,325,1284,3103,2704,2757,56,228,2922,2758,29,153,1011,2509,3191,1701,3538,2510,1789,455,1457,3528,1081,3435,59,1704,2144,1964,3193,308,83,1146,1876,15,2868,3468,410,155,1965,2869,2577,1620,2426,137,3294,2063,1461,3222,3197,3324,3407,2709,707,1623,3425,2710,2432,2935,2237,1229,1805,1632,1806,2349,1023,351,1025,2161,2255,378,2813,2938,254,2167,2442,2985,1238,328,315,1239,2087,2268,1485,1097,1173,340,1106,1741,398,2899,676,1663,331,423,677,1417,1835,3092,980,1675,121,1507,2111,683,2293,115,2837,3211,2693,3240,2306,102,2202,3063,2203,2563,2637,2492,2567,609,877
1.027635769907882,-0.8971691305719629,0.19067127264620573,-0.2609563355332265,0.15884550726049723,1.943054324684516,0.7224199472328477,0.5055225334229401,1.3575144142492008,-0.0012581004565036626,1.7982903969638317,0.9366227945511973,0.12695555655645674,-0.6930805097254553,-0.42560918711049844,-0.4587663248239629,2.6800374279695216,1.1783129469800828,-0.5587053640309138,-0.4587663248239629,3.6353042018995785,1.5350292358486646,0.25413257026133235,-0.3265940252928932,-0.7607655898218467,-0.03347806686168351,-1.3862754857551036,-0.3265940252928932,-0.06576592628969985,0.6916031594494587,0.06298071889501843,-1.3507131280591325,0.2224334357534765,-1.104482929673742,2.5402599154147643,-0.03347806686168351,-0.19560956934146895,-0.13054795621506413,-0.7607655898218467,0.9670119136618348,2.172563346869744,0.19067127264620573,-0.098122333905974,4.964849362308119,-0.525313577596298,-1.174345720866778,0.7531817696547146,1.5350292358486646,-0.13054795621506413,-0.525313577596298,-0.3595238272390506,-0.0012581004565036626,-0.29373844618932715,1.623176179314646,-0.8629365633590367,-0.16304347134508207,0.06298071889501843,-0.7947358122572576,-0.7607655898218467,-0.8971691305719629,-1.0350054838275398,-0.42560918711049844,0.44303477605405855,-0.0012581004565036626,-1.069696640684267,-0.42560918711049844,-0.29373844618932715,-0.5587053640309138,-0.22824695247054547,0.15884550726049723,-0.06576592628969985,-0.0012581004565036626,-0.06576592628969985,-0.2609563355332265,0.25413257026133235,0.8756881681175116,0.25413257026133235,-0.19560956934146895,-0.22824695247054547,0.8145422833591529,-0.4920008457387619,-0.5587053640309138,1.08805639508316,-0.19560956934146895,-0.29373844618932715,-0.5921770650124923,0.15884550726049723,0.9366227945511973,0.9670119136618348,0.15884550726049723,-0.16304347134508207,-0.22824695247054547,0.06298071889501843,0.2224334357534765,0.19067127264620573,0.9061816816409076,0.2224334357534765,-0.03347806686168351,0.7838890695289682,-0.525313577596298,0.47430803058067816,-0.0012581004565036626,0.9366227945511973,0.7531817696547146,0.47430803058067816,0.09500082791205905,-0.06576592628969985,-0.6593637349435877,0.2857692407025649,-0.0012581004565036626,1.7692119702003737,0.06298071889501843,-0.16304347134508207,0.47430803058067816,-0.22824695247054547,1.8563207862044178,-0.4920008457387619,-0.7607655898218467,-0.3925286203228279,-0.7947358122572576,-0.22824695247054547,1.9718833674139287,-0.19560956934146895,-0.6257295573052645,-0.19560956934146895,-0.3265940252928932,-0.3595238272390506,-0.29373844618932715,-0.3265940252928932,0.5366787829519797,0.34885740302862467
3,643
Abnormal peripheral myelination
10
35
2.507014
0.012176
Q9NR77,P20700,P03886,P07602,P00846,P02545,Q01082,P39210,O43681,P07196
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,310,62,69,74,265,365,267,118,125
746,118,1776,791,1454,74,265,62,2967,125,69,591,1878,310,2228,267,1882,1155,2156,2242,3471,365,2363,627,464,813,3091,1675,1423,3533,32,1357,1064,1272,1279
0.4117022638315761,1.7982903969638317,-0.06576592628969985,0.3803099800917596,0.06298071889501843,2.371337868662573,1.0578712931665288,2.512197372488192,-0.5921770650124923,1.7400910153055076,2.427791890653298,0.5366787829519797,-0.098122333905974,0.9670119136618348,-0.22824695247054547,1.0578712931665288,-0.098122333905974,0.19067127264620573,-0.19560956934146895,-0.22824695247054547,-1.174345720866778,0.845141841466991,-0.2609563355332265,0.5055225334229401,0.6916031594494587,0.3803099800917596,-0.6593637349435877,-0.0012581004565036626,0.09500082791205905,-1.3507131280591325,3.6085359292973544,0.12695555655645674,0.25413257026133235,0.15884550726049723,0.15884550726049723
3,643
Immunoglobulin-like fold [IPR013783]
12
37
2.499341
0.012442
P10321,O15344,Q9BY67,Q8IZA0,P30511,Q8NAT1,Q15375,P08236,P10586,Q9BX67,O75592,Q92545
Sequence
InterPro Superfamily
interpro_homologous_superfamily
532,253,304,141,138,480,418,455,119,488,186,226
1072,253,1695,1005,2412,186,1782,1872,590,455,532,119,2337,138,889,2520,2162,2257,1395,1993,1031,2529,418,1909,2730,141,480,973,1184,226,727,488,304,1199,1362,1951,1443
0.2224334357534765,1.08805639508316,-0.03347806686168351,0.25413257026133235,-0.29373844618932715,1.387215394486587,-0.06576592628969985,-0.098122333905974,0.5366787829519797,0.6916031594494587,0.5988184783374502,1.7982903969638317,-0.2609563355332265,1.623176179314646,0.31734400267200297,-0.3265940252928932,-0.19560956934146895,-0.22824695247054547,0.09500082791205905,-0.13054795621506413,0.25413257026133235,-0.3265940252928932,0.7531817696547146,-0.098122333905974,-0.42560918711049844,1.623176179314646,0.6607309570482511,0.2857692407025649,0.19067127264620573,1.2083001127798034,0.44303477605405855,0.6607309570482511,0.9973494401983068,0.19067127264620573,0.12695555655645674,-0.098122333905974,0.09500082791205905
3,643
Plasma membrane organization
11
37
2.499305
0.012444
P35579,P41440,Q9HD42,Q16739,P16615,Q9Y5X1,Q01082,Q8N3R9,O75955,Q9UQB8,Q96CP7
Processes and pathways
GO Biological process
msigdb_gobp
280,90,276,330,172,107,365,148,249,26,64
2793,2963,249,3106,1704,172,592,364,280,90,1628,1155,365,2938,1727,1398,1165,330,3042,148,3356,64,574,549,2388,2391,276,3337,739,1854,1596,26,1690,2404,3493,1437,107
-0.4920008457387619,-0.5921770650124923,1.118191455601226,-0.6930805097254553,-0.03347806686168351,1.4760406150941263,0.5366787829519797,0.845141841466991,1.027635769907882,2.058127752852981,-0.0012581004565036626,0.19067127264620573,0.845141841466991,-0.5587053640309138,-0.03347806686168351,0.09500082791205905,0.19067127264620573,0.9366227945511973,-0.6257295573052645,1.5644560394229112,-0.931491220478586,2.512197372488192,0.5677772700633923,0.5988184783374502,-0.2609563355332265,-0.2609563355332265,1.0578712931665288,-0.8971691305719629,0.44303477605405855,-0.06576592628969985,0.030894617027511038,3.9014137223503935,-0.0012581004565036626,-0.2609563355332265,-1.209424370050621,0.09500082791205905,1.943054324684516
3,643
Proximal muscle weakness
20
65
2.496938
0.012527
Q99720,P51114,Q8TD16,P02545,P06753,Q13126,P10253,Q00796,O60313,Q7Z406,Q9BPX6,Q96RR1,Q13049,P50336,P00846,Q7LG56,Q9H9S5,Q8NAT1,Q8NFF5,P07196
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,504,272,265,394,20,266,156,529,300,320,319,188,313,74,464,347,480,382,125
2049,529,2136,3404,791,1782,74,265,3450,394,125,2142,1376,266,3257,3623,2331,2332,3406,1878,1796,2927,944,753,754,1544,2711,313,849,1155,504,2073,2242,2349,156,2358,188,20,1992,3473,959,2087,2529,1165,1039,1320,464,2606,300,3047,480,382,2538,272,976,813,319,2,320,577,1581,3181,347,2960,1068
-0.16304347134508207,0.5988184783374502,-0.19560956934146895,-1.0350054838275398,0.3803099800917596,-0.06576592628969985,2.371337868662573,1.0578712931665288,-1.1393655482262741,0.7838890695289682,1.7400910153055076,-0.19560956934146895,0.09500082791205905,1.0578712931665288,-0.8287924672030076,-2.7252579017752425,-0.2609563355332265,-0.2609563355332265,-1.0350054838275398,-0.098122333905974,-0.06576592628969985,-0.5587053640309138,0.2857692407025649,0.4117022638315761,0.4117022638315761,0.030894617027511038,-0.42560918711049844,0.9670119136618348,0.34885740302862467,0.19067127264620573,0.6298028841948623,-0.16304347134508207,-0.22824695247054547,-0.2609563355332265,1.5350292358486646,-0.2609563355332265,1.387215394486587,4.39950530014643,-0.13054795621506413,-1.174345720866778,0.2857692407025649,-0.16304347134508207,-0.3265940252928932,0.19067127264620573,0.25413257026133235,0.12695555655645674,0.6916031594494587,-0.3595238272390506,0.9973494401983068,-0.6257295573052645,0.6607309570482511,0.8145422833591529,-0.3265940252928932,1.0578712931665288,0.2857692407025649,0.3803099800917596,0.9670119136618348,8.21990109917503,0.9670119136618348,0.5677772700633923,0.030894617027511038,-0.726880811724572,0.9061816816409076,-0.5587053640309138,0.25413257026133235
3,643
Limb muscle weakness
18
89
2.491181
0.012732
Q9NR77,Q99720,Q8N0X7,P00846,Q7RTS9,Q7Z406,Q14203,Q14739,P02545,P06753,O75298,Q13126,P39210,Q96RR1,Q13049,P07196,P50336,Q00796
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,2,421,74,11,300,415,416,265,394,393,20,267,319,188,125,313,156
2210,646,2049,746,2212,2504,393,2417,791,74,265,2054,394,125,3151,2142,3256,2331,1878,753,592,1544,2431,2711,267,2232,2662,2432,1800,313,849,1155,2156,2073,2242,2716,1387,2349,2880,797,2585,156,1989,801,897,188,20,3473,959,415,2087,2529,416,566,964,2091,1165,1096,2889,1039,2363,1320,3502,1825,2946,464,11,300,3047,3393,421,976,813,2286,3231,2830,2622,1675,319,1053,3176,2,577,1581,32,3519,2960,608,1068
-0.22824695247054547,0.47430803058067816,-0.16304347134508207,0.4117022638315761,-0.22824695247054547,-0.3265940252928932,0.7838890695289682,-0.29373844618932715,0.3803099800917596,2.371337868662573,1.0578712931665288,-0.16304347134508207,0.7838890695289682,1.7400910153055076,-0.726880811724572,-0.19560956934146895,-0.8287924672030076,-0.2609563355332265,-0.098122333905974,0.4117022638315761,0.5366787829519797,0.030894617027511038,-0.29373844618932715,-0.42560918711049844,1.0578712931665288,-0.22824695247054547,-0.3925286203228279,-0.29373844618932715,-0.06576592628969985,0.9670119136618348,0.34885740302862467,0.19067127264620573,-0.19560956934146895,-0.16304347134508207,-0.22824695247054547,-0.42560918711049844,0.09500082791205905,-0.2609563355332265,-0.525313577596298,0.3803099800917596,-0.3595238272390506,1.5350292358486646,-0.13054795621506413,0.3803099800917596,0.31734400267200297,1.387215394486587,4.39950530014643,-1.174345720866778,0.2857692407025649,0.7531817696547146,-0.16304347134508207,-0.3265940252928932,0.7531817696547146,0.5677772700633923,0.2857692407025649,-0.16304347134508207,0.19067127264620573,0.2224334357534765,-0.525313577596298,0.25413257026133235,-0.2609563355332265,0.12695555655645674,-1.244601121096576,-0.06576592628969985,-0.5587053640309138,0.6916031594494587,5.543953911878619,0.9973494401983068,-0.6257295573052645,-1.0004082879139022,0.7531817696547146,0.2857692407025649,0.3803099800917596,-0.22824695247054547,-0.7947358122572576,-0.4920008457387619,-0.3595238272390506,-0.0012581004565036626,0.9670119136618348,0.25413257026133235,-0.726880811724572,8.21990109917503,0.5677772700633923,0.030894617027511038,3.6085359292973544,-1.2798752825252815,-0.5587053640309138,0.5366787829519797,0.25413257026133235
3,643
Positive regulation of production of molecular mediator of immune response
10
26
2.489166
0.012804
P02786,Q7Z434,P30511,P14174,Q01650,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0
Processes and pathways
GO Biological process
msigdb_gobp
409,420,138,15,143,590,87,429,522,227
2502,87,409,590,2509,15,1878,138,2229,1548,143,1727,2526,2535,969,420,2178,1923,914,1928,3235,522,638,2394,227,429
-0.3265940252928932,2.11542427763213,0.7531817696547146,0.5366787829519797,-0.3265940252928932,4.964849362308119,-0.098122333905974,1.623176179314646,-0.22824695247054547,0.030894617027511038,1.5938382520831849,-0.03347806686168351,-0.3265940252928932,-0.3265940252928932,0.2857692407025649,0.7531817696547146,-0.19560956934146895,-0.098122333905974,0.31734400267200297,-0.098122333905974,-0.7947358122572576,0.6298028841948623,0.5055225334229401,-0.2609563355332265,1.2083001127798034,0.7531817696547146
3,643
Sphingolipid metabolic process
10
34
2.489023
0.012809
P16278,P07602,P50897,Q16739,Q8NCC3,O60512,Q9NWW5,Q9NRA0,Q96G23,P06280
Processes and pathways
GO Biological process
msigdb_gobp
155,69,72,330,28,85,251,227,159,153
746,2212,85,701,703,153,1013,69,3538,155,2869,1797,502,1968,72,2938,2166,3473,330,1900,905,809,28,159,426,2388,227,251,1758,2488,1432,1064,2847,1199
0.4117022638315761,-0.22824695247054547,2.144013371443563,0.44303477605405855,0.44303477605405855,1.5350292358486646,0.25413257026133235,2.427791890653298,-1.3862754857551036,1.5350292358486646,-0.525313577596298,-0.06576592628969985,0.6298028841948623,-0.13054795621506413,2.399583395405736,-0.5587053640309138,-0.19560956934146895,-1.174345720866778,0.9366227945511973,-0.098122333905974,0.31734400267200297,0.3803099800917596,3.768713037747525,1.5350292358486646,0.7531817696547146,-0.2609563355332265,1.2083001127798034,1.118191455601226,-0.03347806686168351,-0.29373844618932715,0.09500082791205905,0.25413257026133235,-0.4920008457387619,0.19067127264620573
3,643
FAD/NAD(P)-binding domain superfamily [IPR036188]
6
21
2.486779
0.012891
Q9UHG3,Q8NB78,O95831,P00390,Q96CU9,P50336
Sequence
InterPro Superfamily
interpro_homologous_superfamily
430,128,47,25,92,313
1864,47,25,2143,1798,753,1462,891,313,2935,2673,2774,2272,857,128,676,1415,92,2118,430,434
-0.098122333905974,3.0119856905575273,3.9014137223503935,-0.19560956934146895,-0.06576592628969985,0.4117022638315761,0.06298071889501843,0.31734400267200297,0.9670119136618348,-0.5587053640309138,-0.3925286203228279,-0.4587663248239629,-0.22824695247054547,0.34885740302862467,1.7109272480905777,0.47430803058067816,0.09500082791205905,2.0294198239892403,-0.16304347134508207,0.7531817696547146,0.7531817696547146
3,643
Calcium ion import
9
17
2.486382
0.012905
P21796,Q9NWR8,P16615,Q9H4I9,P14373,Q9BPX6,O75844,Q8IYU8,Q9NRA0
Processes and pathways
GO Biological process
msigdb_gobp
34,305,172,244,395,320,248,257,227
436,248,395,172,1084,34,2517,708,3079,257,2949,2468,320,244,227,305,608
0.7224199472328477,1.118191455601226,0.7838890695289682,1.4760406150941263,0.2224334357534765,3.528055524230381,-0.3265940252928932,0.44303477605405855,-0.6593637349435877,1.08805639508316,-0.5587053640309138,-0.29373844618932715,0.9670119136618348,1.1482768495977804,1.2083001127798034,0.9973494401983068,0.5366787829519797
3,643
Disproportionate short stature
10
27
2.485357
0.012942
O00116,P16278,Q9UHX1,Q8WVQ1,Q7RTS9,Q15392,O75718,Q96HY6,Q9Y366,Q9UBM7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
374,155,171,423,11,45,295,384,290,289
374,584,2412,295,3288,1377,155,2516,707,1086,2713,1403,416,900,45,2728,1172,3413,11,1500,423,2183,384,3001,289,171,290
0.8145422833591529,0.5366787829519797,-0.29373844618932715,0.9973494401983068,-0.8629365633590367,0.09500082791205905,1.5350292358486646,-0.3265940252928932,0.44303477605405855,0.2224334357534765,-0.42560918711049844,0.09500082791205905,0.7531817696547146,0.31734400267200297,3.1215736355280526,-0.42560918711049844,0.19067127264620573,-1.0350054838275398,5.543953911878619,0.06298071889501843,0.7531817696547146,-0.19560956934146895,0.8145422833591529,-0.5921770650124923,1.027635769907882,1.5055575321040489,1.027635769907882
3,643
Immunity
16
81
2.482442
0.013049
Q9UQ84,P46379,P10321,Q8IV08,Q15233,O00584,Q9BY67,Q7Z434,Q9NZ08,P30511,Q8WXW3,P14174,O60858,P12956,Q9H2U1,P23246
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
33,3,532,73,567,103,304,420,245,138,468,15,80,83,522,375
1209,103,1365,1210,2410,2574,2794,80,2796,1616,1537,1872,2508,2863,590,1081,532,1704,83,1146,15,1083,1084,1878,2225,375,2762,616,138,1547,890,3,1888,797,1390,3038,1028,1310,1394,2441,1092,2084,715,1031,2814,1563,567,2531,2776,2455,1575,420,1828,73,2993,1111,468,2178,1258,1834,3311,2621,1261,1677,919,3002,304,3211,3479,522,2394,987,989,3242,1356,245,3063,926,33,1692,2496
0.15884550726049723,1.943054324684516,0.09500082791205905,0.15884550726049723,-0.29373844618932715,-0.3595238272390506,-0.4920008457387619,2.2579809707838456,-0.4920008457387619,-0.0012581004565036626,0.030894617027511038,-0.098122333905974,-0.3265940252928932,-0.525313577596298,0.5366787829519797,0.2224334357534765,0.5988184783374502,-0.03347806686168351,2.172563346869744,0.19067127264620573,4.964849362308119,0.2224334357534765,0.2224334357534765,-0.098122333905974,-0.22824695247054547,0.8145422833591529,-0.4587663248239629,0.5055225334229401,1.623176179314646,0.030894617027511038,0.31734400267200297,7.00443820279511,-0.098122333905974,0.3803099800917596,0.09500082791205905,-0.6257295573052645,0.25413257026133235,0.12695555655645674,0.09500082791205905,-0.29373844618932715,0.2224334357534765,-0.16304347134508207,0.44303477605405855,0.25413257026133235,-0.4920008457387619,0.030894617027511038,0.5677772700633923,-0.3265940252928932,-0.4587663248239629,-0.29373844618932715,0.030894617027511038,0.7531817696547146,-0.06576592628969985,2.399583395405736,-0.5921770650124923,0.2224334357534765,0.6916031594494587,-0.19560956934146895,0.15884550726049723,-0.06576592628969985,-0.8629365633590367,-0.3595238272390506,0.15884550726049723,-0.0012581004565036626,0.31734400267200297,-0.5921770650124923,0.9973494401983068,-0.7607655898218467,-1.174345720866778,0.6298028841948623,-0.2609563355332265,0.2857692407025649,0.2857692407025649,-0.7947358122572576,0.12695555655645674,1.1482768495977804,-0.6257295573052645,0.31734400267200297,3.6085359292973544,-0.0012581004565036626,-0.29373844618932715
3,643
Biliary tract abnormality
7
30
2.482149
0.013059
Q14108,P07602,O15078,P14174,O43681,O96028,Q9NUN5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
255,69,194,15,118,87,123
194,118,1372,87,265,703,69,653,15,3437,1973,3155,1802,2238,2242,658,803,1562,255,416,1491,2378,2621,3212,2483,123,1064,1202,2789,1604
1.3575144142492008,1.7982903969638317,0.09500082791205905,2.11542427763213,1.0578712931665288,0.44303477605405855,2.427791890653298,0.47430803058067816,4.964849362308119,-1.104482929673742,-0.13054795621506413,-0.726880811724572,-0.06576592628969985,-0.22824695247054547,-0.22824695247054547,0.47430803058067816,0.3803099800917596,0.030894617027511038,1.08805639508316,0.7531817696547146,0.06298071889501843,-0.2609563355332265,-0.3595238272390506,-0.7607655898218467,-0.29373844618932715,1.7692119702003737,0.25413257026133235,0.19067127264620573,-0.4587663248239629,0.030894617027511038
3,643
Incoordination
15
76
2.480622
0.013115
Q9NR77,O00754,P07602,Q7RTS9,P00846,O75787,P06753,Q9H9S5,O14773,O43681,O75530,O75503,Q96RR1,Q9NUN5,Q6DKK2
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,435,69,11,74,296,394,347,391,118,86,24,319,123,190
1770,1862,435,391,1210,2571,118,2504,1078,3404,24,86,296,791,1454,74,703,394,69,3257,2331,1876,1796,844,753,2431,2232,1718,1885,2073,2242,2349,2880,797,3162,505,2721,2358,658,3473,959,2087,964,1165,668,2452,190,2729,1827,464,11,1493,1106,3276,1834,2622,728,2624,319,820,3178,3212,347,1429,3535,32,123,1849,1850,1064,1521,2913,1274,1853,1068,693
-0.06576592628969985,-0.098122333905974,0.7224199472328477,0.7838890695289682,0.15884550726049723,-0.3595238272390506,1.7982903969638317,-0.3265940252928932,0.2224334357534765,-1.0350054838275398,4.11230346222967,2.11542427763213,0.9973494401983068,0.3803099800917596,0.06298071889501843,2.371337868662573,0.44303477605405855,0.7838890695289682,2.427791890653298,-0.8287924672030076,-0.2609563355332265,-0.098122333905974,-0.06576592628969985,0.34885740302862467,0.4117022638315761,-0.29373844618932715,-0.22824695247054547,-0.03347806686168351,-0.098122333905974,-0.16304347134508207,-0.22824695247054547,-0.2609563355332265,-0.525313577596298,0.3803099800917596,-0.726880811724572,0.6298028841948623,-0.42560918711049844,-0.2609563355332265,0.47430803058067816,-1.174345720866778,0.2857692407025649,-0.16304347134508207,0.2857692407025649,0.19067127264620573,0.47430803058067816,-0.29373844618932715,1.387215394486587,-0.42560918711049844,-0.06576592628969985,0.6916031594494587,5.543953911878619,0.06298071889501843,0.2224334357534765,-0.8287924672030076,-0.06576592628969985,-0.3595238272390506,0.44303477605405855,-0.3595238272390506,0.9670119136618348,0.3803099800917596,-0.726880811724572,-0.7607655898218467,0.9061816816409076,0.09500082791205905,-1.3507131280591325,3.6085359292973544,1.7692119702003737,-0.06576592628969985,-0.06576592628969985,0.25413257026133235,0.06298071889501843,-0.525313577596298,0.15884550726049723,-0.06576592628969985,0.25413257026133235,0.47430803058067816
3,643
Golgi apparatus
61
235
2.471804
0.013443
O15344,Q92896,Q9HC07,Q6NT16,Q7RTS9,Q8IXU6,Q8IZA0,O43493,Q8TD16,Q9HD45,Q86SX3,O60476,Q5KU26,O14976,Q5VW38,P05067,Q8IYS2,P16278,P11717,O00231,Q9HB40,Q8NCH0,Q8WVQ1,P22466,Q08379,O75071,Q9NPR9,Q02818,O60499,O15127,P50897,O00461,Q8NBJ4,Q8IWJ2,Q5VU43,Q93050,Q9H9S5,O43752,O60512,Q9H3P7,Q9BX67,P80303,Q969M3,Q8NBN3,Q9BRK5,O60637,Q6ZVM7,Q15012,Q5SRI9,Q9NX62,Q96CN9,P35606,O15260,Q99523,Q01082,P15291,O75955,P10586,O95456,Q8TBA6,A4D1U4
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
253,136,405,10,11,12,141,142,272,277,271,264,396,392,23,29,157,155,154,278,35,422,423,38,414,40,48,65,196,195,72,70,75,465,208,82,347,454,85,523,488,93,356,225,96,220,381,353,478,231,368,474,108,114,365,112,249,119,250,383,246
1070,528,246,2569,1952,278,70,2133,1530,1445,392,1608,195,1002,1073,108,253,1003,2215,2962,2858,2859,142,3402,454,1533,264,1865,196,85,220,837,1217,40,3496,2412,3067,249,700,1140,250,2651,590,29,3319,653,119,3220,154,112,155,3070,1797,38,562,2801,2763,2340,1383,3199,474,2932,3116,1019,1628,1629,2713,795,1802,1155,1020,72,3386,1553,1302,3558,2241,2521,2243,1889,2768,3571,2254,93,2881,2591,1477,365,65,2938,2438,414,1159,1160,3620,3121,564,2444,1402,2941,3600,353,963,3205,3581,542,396,666,478,3602,2775,208,2679,23,3349,2452,2945,2001,10,3045,1905,3596,2776,1907,2821,971,2003,381,11,1575,629,271,1741,771,3624,810,2277,465,1179,12,1411,157,141,2280,3353,3306,2463,1329,75,225,422,3525,1746,383,272,1416,2829,423,677,515,136,2103,82,2612,2379,356,2613,1259,2181,368,3232,2951,3051,604,2543,2623,2185,2686,1505,1263,114,982,2952,3427,96,2294,1344,2909,1841,2296,488,1347,3237,3506,1268,2300,3239,1350,523,3554,2479,3213,2694,347,3214,35,405,1844,277,1193,48,2553,871,1125,3377,3183,737,231,1520,3604,2489,2400,3062,1946,2914,3008,1593,2851,927,2854,743,1362,832,1439,610
0.2224334357534765,0.5988184783374502,1.118191455601226,-0.3595238272390506,-0.13054795621506413,1.027635769907882,2.399583395405736,-0.19560956934146895,0.030894617027511038,0.06298071889501843,0.7838890695289682,-0.0012581004565036626,1.3575144142492008,0.25413257026133235,0.2224334357534765,1.914184390727662,1.08805639508316,0.25413257026133235,-0.22824695247054547,-0.5921770650124923,-0.525313577596298,-0.525313577596298,1.5938382520831849,-1.0350054838275398,0.6916031594494587,0.030894617027511038,1.0578712931665288,-0.098122333905974,1.3575144142492008,2.144013371443563,1.2083001127798034,0.34885740302862467,0.15884550726049723,3.2306497156014906,-1.244601121096576,-0.29373844618932715,-0.6593637349435877,1.118191455601226,0.44303477605405855,0.19067127264620573,1.118191455601226,-0.3925286203228279,0.5366787829519797,3.6353042018995785,-0.8971691305719629,0.47430803058067816,1.7982903969638317,-0.7947358122572576,1.5350292358486646,1.8563207862044178,1.5350292358486646,-0.6593637349435877,-0.06576592628969985,3.257840018273795,0.5677772700633923,-0.4920008457387619,-0.4587663248239629,-0.2609563355332265,0.09500082791205905,-0.7607655898218467,0.6607309570482511,-0.5587053640309138,-0.6930805097254553,0.25413257026133235,-0.0012581004565036626,-0.0012581004565036626,-0.42560918711049844,0.3803099800917596,-0.06576592628969985,0.19067127264620573,0.25413257026133235,2.399583395405736,-1.0004082879139022,0.030894617027511038,0.12695555655645674,-1.4935285643358234,-0.22824695247054547,-0.3265940252928932,-0.22824695247054547,-0.098122333905974,-0.4587663248239629,-1.5654960467228805,-0.22824695247054547,2.0006717808585845,-0.525313577596298,-0.3595238272390506,0.06298071889501843,0.845141841466991,2.4840986629825825,-0.5587053640309138,-0.29373844618932715,0.7531817696547146,0.19067127264620573,0.19067127264620573,-2.3803772184572165,-0.6930805097254553,0.5677772700633923,-0.29373844618932715,0.09500082791205905,-0.5587053640309138,-1.8938214246167355,0.8756881681175116,0.2857692407025649,-0.7607655898218467,-1.63783022894056,0.5988184783374502,0.7838890695289682,0.47430803058067816,0.6607309570482511,-1.8938214246167355,-0.4587663248239629,1.2979715997804608,-0.3925286203228279,4.295431147653506,-0.931491220478586,-0.29373844618932715,-0.5587053640309138,-0.13054795621506413,5.593769792208002,-0.6257295573052645,-0.098122333905974,-1.7835801457881182,-0.4587663248239629,-0.098122333905974,-0.4920008457387619,0.2857692407025649,-0.13054795621506413,0.8145422833591529,5.543953911878619,0.030894617027511038,0.5055225334229401,1.0578712931665288,-0.03347806686168351,0.4117022638315761,-2.763967375035913,0.3803099800917596,-0.22824695247054547,0.6916031594494587,0.19067127264620573,5.444068869967951,0.09500082791205905,1.5350292358486646,1.623176179314646,-0.22824695247054547,-0.931491220478586,-0.8629365633590367,-0.29373844618932715,0.12695555655645674,2.371337868662573,1.2083001127798034,0.7531817696547146,-1.315246174406957,-0.03347806686168351,0.8145422833591529,1.0578712931665288,0.09500082791205905,-0.4920008457387619,0.7531817696547146,0.47430803058067816,0.6298028841948623,1.6524701228970238,-0.16304347134508207,2.2010744460285183,-0.3595238272390506,-0.2609563355332265,0.8756881681175116,-0.3595238272390506,0.15884550726049723,-0.19560956934146895,0.845141841466991,-0.7947358122572576,-0.5587053640309138,-0.6257295573052645,0.5366787829519797,-0.3265940252928932,-0.3595238272390506,-0.19560956934146895,-0.3925286203228279,0.06298071889501843,0.15884550726049723,1.8563207862044178,0.2857692407025649,-0.5587053640309138,-1.069696640684267,2.0006717808585845,-0.22824695247054547,0.12695555655645674,-0.525313577596298,-0.06576592628969985,-0.22824695247054547,0.6607309570482511,0.12695555655645674,-0.7947358122572576,-1.244601121096576,0.15884550726049723,-0.22824695247054547,-0.7947358122572576,0.12695555655645674,0.6298028841948623,-1.4576838354723742,-0.29373844618932715,-0.7607655898218467,-0.3925286203228279,0.9061816816409076,-0.7607655898218467,3.447308651903207,0.7838890695289682,-0.06576592628969985,1.0578712931665288,0.19067127264620573,3.0119856905575273,-0.3265940252928932,0.34885740302862467,0.2224334357534765,-0.9659039071751861,-0.726880811724572,0.44303477605405855,1.1783129469800828,0.06298071889501843,-1.8938214246167355,-0.29373844618932715,-0.2609563355332265,-0.6257295573052645,-0.098122333905974,-0.525313577596298,-0.5921770650124923,0.030894617027511038,-0.4920008457387619,0.31734400267200297,-0.4920008457387619,0.44303477605405855,0.12695555655645674,0.3803099800917596,0.09500082791205905,0.5366787829519797
3,643
Proteasome core complex
6
15
2.469558
0.013528
P28070,P28074,P20618,P28072,Q99436,P49721
Localization
GO Cellular component
msigdb_gocc
164,41,137,146,121,60
3142,137,2762,1461,1621,2802,3222,164,146,41,2878,60,283,2013,121
-0.726880811724572,1.623176179314646,-0.4587663248239629,0.06298071889501843,-0.0012581004565036626,-0.4920008457387619,-0.7947358122572576,1.5055575321040489,1.5644560394229112,3.2306497156014906,-0.525313577596298,2.5402599154147643,1.027635769907882,-0.13054795621506413,1.7692119702003737
3,643
Neuron apoptotic process
13
49
2.463366
0.013764
Q99720,Q01105,P50897,Q13464,Q96A26,O95831,Q15375,P31751,P07196,Q99538,Q969N2,Q92542,P05067
Processes and pathways
GO Biological process
msigdb_gobp
2,505,72,328,243,47,418,364,125,520,318,317,29
1606,3495,2861,881,885,47,703,3291,2863,1288,29,2509,125,1457,653,1791,840,364,3520,708,1548,3155,2582,757,2236,1800,72,1301,2584,1723,2806,3079,505,506,328,1401,567,418,317,318,243,3332,3177,520,2,1056,779,1855,1768
-0.0012581004565036626,-1.244601121096576,-0.525313577596298,0.31734400267200297,0.31734400267200297,3.0119856905575273,0.44303477605405855,-0.8629365633590367,-0.525313577596298,0.12695555655645674,3.6353042018995785,-0.3265940252928932,1.7400910153055076,0.06298071889501843,0.47430803058067816,-0.06576592628969985,0.34885740302862467,0.845141841466991,-1.315246174406957,0.44303477605405855,0.030894617027511038,-0.726880811724572,-0.3595238272390506,0.4117022638315761,-0.22824695247054547,-0.06576592628969985,2.399583395405736,0.12695555655645674,-0.3595238272390506,-0.03347806686168351,-0.4920008457387619,-0.6593637349435877,0.6298028841948623,0.6298028841948623,0.9366227945511973,0.09500082791205905,0.5677772700633923,0.7531817696547146,0.9670119136618348,0.9670119136618348,1.1482768495977804,-0.8971691305719629,-0.726880811724572,0.6298028841948623,8.21990109917503,0.25413257026133235,0.4117022638315761,-0.06576592628969985,-0.03347806686168351
3,643
Abnormal femoral neck head morphology
17
51
2.461214
0.013847
P16278,O00754,P55011,P04066,Q8WVQ1,Q96L58,Q9Y487,Q7RTS9,O75718,Q14739,P02545,O95831,O75431,O75530,O75844,P11274,Q96HY6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
155,435,440,228,423,303,43,11,295,416,265,47,213,86,248,338,384
834,435,1958,2412,213,86,295,248,47,265,228,338,155,2337,2147,3197,707,3031,2933,3117,2713,1802,3626,440,2434,416,900,806,1038,2364,1905,2003,3413,11,2458,423,2612,1048,1112,384,303,2185,3052,3003,3096,524,2041,3012,43,1069,693
0.34885740302862467,0.7224199472328477,-0.13054795621506413,-0.29373844618932715,1.2382387072449188,2.11542427763213,0.9973494401983068,1.118191455601226,3.0119856905575273,1.0578712931665288,1.1783129469800828,0.9061816816409076,1.5350292358486646,-0.2609563355332265,-0.19560956934146895,-0.7607655898218467,0.44303477605405855,-0.6257295573052645,-0.5587053640309138,-0.6930805097254553,-0.42560918711049844,-0.06576592628969985,-2.919565762049335,0.7224199472328477,-0.29373844618932715,0.7531817696547146,0.31734400267200297,0.3803099800917596,0.25413257026133235,-0.2609563355332265,-0.098122333905974,-0.13054795621506413,-1.0350054838275398,5.543953911878619,-0.29373844618932715,0.7531817696547146,-0.3595238272390506,0.25413257026133235,0.2224334357534765,0.8145422833591529,0.9973494401983068,-0.19560956934146895,-0.6257295573052645,-0.5921770650124923,-0.6593637349435877,0.6298028841948623,-0.13054795621506413,-0.5921770650124923,3.2306497156014906,0.25413257026133235,0.47430803058067816
3,643
Regulation of ph
8
24
2.457298
0.013999
P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7
Processes and pathways
GO Biological process
msigdb_gobp
72,405,43,296,82,251,24,361
24,296,1962,2141,1144,3322,3197,72,2156,459,2587,1036,965,1914,1331,82,2180,405,251,1274,2401,43,3315,361
4.11230346222967,0.9973494401983068,-0.13054795621506413,-0.19560956934146895,0.19067127264620573,-0.8971691305719629,-0.7607655898218467,2.399583395405736,-0.19560956934146895,0.6916031594494587,-0.3595238272390506,0.25413257026133235,0.2857692407025649,-0.098122333905974,0.12695555655645674,2.2010744460285183,-0.19560956934146895,0.7838890695289682,1.118191455601226,0.15884550726049723,-0.2609563355332265,3.2306497156014906,-0.8629365633590367,0.8756881681175116
3,643
Regulation of cellular ph
8
24
2.457298
0.013999
P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7
Processes and pathways
GO Biological process
msigdb_gobp
72,405,43,296,82,251,24,361
24,296,1962,2141,1144,3322,3197,72,2156,459,2587,1036,965,1914,1331,82,2180,405,251,1274,2401,43,3315,361
4.11230346222967,0.9973494401983068,-0.13054795621506413,-0.19560956934146895,0.19067127264620573,-0.8971691305719629,-0.7607655898218467,2.399583395405736,-0.19560956934146895,0.6916031594494587,-0.3595238272390506,0.25413257026133235,0.2857692407025649,-0.098122333905974,0.12695555655645674,2.2010744460285183,-0.19560956934146895,0.7838890695289682,1.118191455601226,0.15884550726049723,-0.2609563355332265,3.2306497156014906,-0.8629365633590367,0.8756881681175116
3,643
Biological adhesion
43
200
2.455423
0.014072
P07942,Q08380,Q9HCL2,Q8WTV0,Q9BQT9,Q13136,Q92797,Q9UM22,O00192,Q9UQB8,P05067,P46939,P35579,Q9BY67,Q96JJ3,P02786,P16615,P80404,O75116,Q15375,Q9UBT7,P30825,P00813,O14936,P23396,P12814,Q13464,O43707,Q13641,Q14168,Q96F07,P09493,P78536,Q9BX67,P41440,P11274,Q14185,Q9NUQ9,P35580,P15291,P57105,O75955,P10586
Processes and pathways
GO Biological process
msigdb_gobp
126,254,5,8,275,269,149,22,389,26,29,281,280,304,302,409,172,413,293,418,323,54,56,436,437,308,328,325,329,211,344,215,216,488,90,338,94,102,222,112,238,249,119
2916,1207,389,1952,3065,2792,3610,1606,436,1607,1072,1448,2215,325,789,1076,1959,293,3496,1005,2136,249,1783,1786,2757,56,409,2508,590,3149,29,3218,2141,1012,3150,3191,126,1457,3069,1081,215,119,1377,3256,3257,338,308,3468,112,941,3552,3629,172,942,1084,1620,843,2337,2063,437,501,2658,1968,54,592,2709,2874,534,708,2068,280,222,889,2932,1547,90,3325,2712,3117,281,3440,1630,1801,1155,3344,2240,1554,1633,238,2244,1723,1890,3268,3368,3409,3077,1557,1156,3120,2162,216,3038,413,1477,1988,3079,2259,2938,1815,1310,1029,3270,254,1395,1727,1398,2940,803,269,1993,1994,328,1896,329,1031,1033,3225,2267,211,94,1402,1315,1996,1166,418,3541,2601,2271,855,1097,904,1246,3169,1323,8,1184,1331,2015,1334,3173,149,978,1049,2619,344,574,1186,1339,2621,302,863,2737,275,2549,488,304,489,2389,1513,3057,3533,3213,2116,1269,5,1192,2742,102,1587,1686,783,1200,1760,323,2037,990,1361,22,2636,928,26,1362,2566,2206,2496,1859,1204,1951,1443,555
-0.5587053640309138,0.15884550726049723,0.7838890695289682,-0.13054795621506413,-0.6593637349435877,-0.4920008457387619,-2.1540615170130093,-0.0012581004565036626,0.7224199472328477,-0.0012581004565036626,0.2224334357534765,0.06298071889501843,-0.22824695247054547,0.9366227945511973,0.3803099800917596,0.2224334357534765,-0.13054795621506413,0.9973494401983068,-1.244601121096576,0.25413257026133235,-0.19560956934146895,1.118191455601226,-0.06576592628969985,-0.06576592628969985,-0.4587663248239629,2.6800374279695216,0.7531817696547146,-0.3265940252928932,0.5366787829519797,-0.726880811724572,3.6353042018995785,-0.7947358122572576,-0.19560956934146895,0.25413257026133235,-0.726880811724572,-0.7607655898218467,1.7109272480905777,0.06298071889501843,-0.6593637349435877,0.2224334357534765,1.2382387072449188,1.7982903969638317,0.09500082791205905,-0.8287924672030076,-0.8287924672030076,0.9061816816409076,0.9670119136618348,-1.174345720866778,1.8563207862044178,0.2857692407025649,-1.4576838354723742,-2.997816021189173,1.4760406150941263,0.2857692407025649,0.2224334357534765,-0.0012581004565036626,0.34885740302862467,-0.2609563355332265,-0.16304347134508207,0.7224199472328477,0.6298028841948623,-0.3925286203228279,-0.13054795621506413,2.707887319665007,0.5366787829519797,-0.42560918711049844,-0.525313577596298,0.5988184783374502,0.44303477605405855,-0.16304347134508207,1.027635769907882,1.2083001127798034,0.31734400267200297,-0.5587053640309138,0.030894617027511038,2.058127752852981,-0.8971691305719629,-0.42560918711049844,-0.6930805097254553,1.027635769907882,-1.104482929673742,-0.0012581004565036626,-0.06576592628969985,0.19067127264620573,-0.931491220478586,-0.22824695247054547,0.030894617027511038,-0.0012581004565036626,1.1482768495977804,-0.22824695247054547,-0.03347806686168351,-0.098122333905974,-0.8287924672030076,-0.9659039071751861,-1.0350054838275398,-0.6593637349435877,0.030894617027511038,0.19067127264620573,-0.6930805097254553,-0.19560956934146895,1.2382387072449188,-0.6257295573052645,0.7531817696547146,0.06298071889501843,-0.13054795621506413,-0.6593637349435877,-0.22824695247054547,-0.5587053640309138,-0.06576592628969985,0.12695555655645674,0.25413257026133235,-0.8287924672030076,1.08805639508316,0.09500082791205905,-0.03347806686168351,0.09500082791205905,-0.5587053640309138,0.3803099800917596,1.0578712931665288,-0.13054795621506413,-0.13054795621506413,0.9366227945511973,-0.098122333905974,0.9366227945511973,0.25413257026133235,0.25413257026133235,-0.7947358122572576,-0.22824695247054547,1.268129085929357,2.0006717808585845,0.09500082791205905,0.12695555655645674,-0.13054795621506413,0.19067127264620573,0.7531817696547146,-1.3862754857551036,-0.3595238272390506,-0.22824695247054547,0.34885740302862467,0.2224334357534765,0.31734400267200297,0.15884550726049723,-0.726880811724572,0.12695555655645674,5.940175937290734,0.19067127264620573,0.12695555655645674,-0.13054795621506413,0.12695555655645674,-0.726880811724572,1.5644560394229112,0.2857692407025649,0.25413257026133235,-0.3595238272390506,0.9061816816409076,0.5677772700633923,0.19067127264620573,0.12695555655645674,-0.3595238272390506,0.9973494401983068,0.34885740302862467,-0.42560918711049844,1.0578712931665288,-0.3265940252928932,0.6607309570482511,0.9973494401983068,0.6607309570482511,-0.2609563355332265,0.06298071889501843,-0.6257295573052645,-1.3507131280591325,-0.7607655898218467,-0.16304347134508207,0.15884550726049723,6.233993929662534,0.19067127264620573,-0.42560918711049844,1.9718833674139287,0.030894617027511038,-0.0012581004565036626,0.4117022638315761,0.19067127264620573,-0.03347806686168351,0.9670119136618348,-0.13054795621506413,0.2857692407025649,0.12695555655645674,4.373525061543824,-0.3595238272390506,0.31734400267200297,3.9014137223503935,0.12695555655645674,-0.3265940252928932,-0.19560956934146895,-0.29373844618932715,-0.06576592628969985,0.19067127264620573,-0.098122333905974,0.09500082791205905,0.5988184783374502
3,643
Phospholipid binding
29
106
2.453656
0.014141
Q92538,Q13045,Q14108,Q8WTV0,Q9H1P3,O14773,Q9UM22,O00291,Q8NCC3,Q9Y5X2,O60313,P21796,Q06481,Q96L92,P20073,P07602,P50897,P45880,Q9Y4G8,O14523,O60749,Q15075,Q9Y5X1,Q53T59,Q01082,Q9NS86,O95219,Q9NWW5,Q6ZVM7
Functions
GO Molecular function
msigdb_gomf
515,507,255,8,549,391,22,390,28,433,529,34,39,575,560,69,72,78,81,453,588,354,107,366,365,117,235,251,381
1206,390,834,2322,453,391,1774,2571,3101,2216,2963,1004,529,1213,588,2700,1367,235,1787,2508,3191,69,1080,3106,1081,2144,3023,3591,560,34,1797,1381,592,3261,2431,78,3035,709,2934,72,3265,1302,3558,2163,365,39,3411,507,2596,2528,1030,255,2088,1163,2530,354,902,366,666,1572,381,1494,1911,2372,1410,2948,28,3477,8,515,1921,3308,1049,575,3179,2999,2688,2114,984,3212,1424,549,2479,3213,2116,117,2695,251,1432,1064,1944,3008,2308,1854,22,3285,1596,1855,3585,1437,2206,81,107,433,2407,1525
0.15884550726049723,0.7838890695289682,0.34885740302862467,-0.2609563355332265,0.6916031594494587,0.7838890695289682,-0.06576592628969985,-0.3595238272390506,-0.6930805097254553,-0.22824695247054547,-0.5921770650124923,0.25413257026133235,0.5988184783374502,0.15884550726049723,0.5366787829519797,-0.42560918711049844,0.09500082791205905,1.1482768495977804,-0.06576592628969985,-0.3265940252928932,-0.7607655898218467,2.427791890653298,0.2224334357534765,-0.6930805097254553,0.2224334357534765,-0.19560956934146895,-0.6257295573052645,-1.7470088834303552,0.5677772700633923,3.528055524230381,-0.06576592628969985,0.09500082791205905,0.5366787829519797,-0.8287924672030076,-0.29373844618932715,2.286376867508823,-0.6257295573052645,0.44303477605405855,-0.5587053640309138,2.399583395405736,-0.8287924672030076,0.12695555655645674,-1.4935285643358234,-0.19560956934146895,0.845141841466991,3.257840018273795,-1.0350054838275398,0.6298028841948623,-0.3595238272390506,-0.3265940252928932,0.25413257026133235,1.08805639508316,-0.16304347134508207,0.19067127264620573,-0.3265940252928932,0.8756881681175116,0.31734400267200297,0.845141841466991,0.47430803058067816,0.030894617027511038,0.8145422833591529,0.06298071889501843,-0.098122333905974,-0.2609563355332265,0.09500082791205905,-0.5587053640309138,3.768713037747525,-1.174345720866778,5.940175937290734,0.6298028841948623,-0.098122333905974,-0.8629365633590367,0.25413257026133235,0.5677772700633923,-0.726880811724572,-0.5921770650124923,-0.3925286203228279,-0.16304347134508207,0.2857692407025649,-0.7607655898218467,0.09500082791205905,0.5988184783374502,-0.29373844618932715,-0.7607655898218467,-0.16304347134508207,1.8273265764439528,-0.3925286203228279,1.118191455601226,0.09500082791205905,0.25413257026133235,-0.098122333905974,-0.5921770650124923,-0.22824695247054547,-0.06576592628969985,4.373525061543824,-0.8287924672030076,0.030894617027511038,-0.06576592628969985,-1.6741333670170677,0.09500082791205905,-0.19560956934146895,2.2579809707838456,1.943054324684516,0.7531817696547146,-0.2609563355332265,0.06298071889501843
3,643
Abnormality of the peripheral nervous system
23
108
2.446171
0.014438
Q99720,Q71SY5,P02545,P39210,O00192,Q9UBM7,Q96EK5,P06280,Q00796,Q9NR77,Q7Z406,O95831,P42892,Q96RR1,P50336,P20700,P07602,O15078,Q8WXW3,P41440,O43681,P07196,Q9GZY8
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,144,265,267,389,289,425,153,156,32,300,47,53,319,313,310,69,194,468,90,118,125,130
389,1210,194,746,2212,585,118,1696,1776,529,1078,881,791,1454,1456,47,265,703,153,125,69,3538,3572,1878,1222,310,2515,1713,1971,3296,2764,2711,267,1546,2662,90,53,890,2933,1467,1800,313,1155,2156,1301,2238,2074,2242,2349,3408,3471,156,1989,2721,955,658,3328,3490,2087,899,964,2091,2887,627,1825,1407,2946,1827,144,464,300,859,673,2608,2734,468,813,1334,2100,425,2835,728,2624,1675,319,1053,3177,2,3561,130,3212,821,3533,2482,32,2556,988,2034,1064,3243,1521,289,2490,1853,2565,1767,1604,693
0.7838890695289682,0.15884550726049723,1.3575144142492008,0.4117022638315761,-0.22824695247054547,0.5366787829519797,1.7982903969638317,-0.03347806686168351,-0.06576592628969985,0.5988184783374502,0.2224334357534765,0.31734400267200297,0.3803099800917596,0.06298071889501843,0.06298071889501843,3.0119856905575273,1.0578712931665288,0.44303477605405855,1.5350292358486646,1.7400910153055076,2.427791890653298,-1.3862754857551036,-1.6016175956969314,-0.098122333905974,0.15884550726049723,0.9670119136618348,-0.3265940252928932,-0.03347806686168351,-0.13054795621506413,-0.8629365633590367,-0.4587663248239629,-0.42560918711049844,1.0578712931665288,0.030894617027511038,-0.3925286203228279,2.058127752852981,2.763483088965262,0.31734400267200297,-0.5587053640309138,0.06298071889501843,-0.06576592628969985,0.9670119136618348,0.19067127264620573,-0.19560956934146895,0.12695555655645674,-0.22824695247054547,-0.16304347134508207,-0.22824695247054547,-0.2609563355332265,-1.0350054838275398,-1.174345720866778,1.5350292358486646,-0.13054795621506413,-0.42560918711049844,0.2857692407025649,0.47430803058067816,-0.8971691305719629,-1.209424370050621,-0.16304347134508207,0.31734400267200297,0.2857692407025649,-0.16304347134508207,-0.525313577596298,0.5055225334229401,-0.06576592628969985,0.09500082791205905,-0.5587053640309138,-0.06576592628969985,1.5938382520831849,0.6916031594494587,0.9973494401983068,0.34885740302862467,0.47430803058067816,-0.3595238272390506,-0.42560918711049844,0.6916031594494587,0.3803099800917596,0.12695555655645674,-0.16304347134508207,0.7531817696547146,-0.4920008457387619,0.44303477605405855,-0.3595238272390506,-0.0012581004565036626,0.9670119136618348,0.25413257026133235,-0.726880811724572,8.21990109917503,-1.4935285643358234,1.7109272480905777,-0.7607655898218467,0.3803099800917596,-1.3507131280591325,-0.29373844618932715,3.6085359292973544,-0.3265940252928932,0.2857692407025649,-0.13054795621506413,0.25413257026133235,-0.7947358122572576,0.06298071889501843,1.027635769907882,-0.29373844618932715,-0.06576592628969985,-0.3265940252928932,-0.03347806686168351,0.030894617027511038,0.47430803058067816
3,643
Positive regulation of cytokine production involved in immune response
7
13
2.43641
0.014834
Q7Z434,P30511,P14174,Q01650,Q9NY93,Q9H2U1,Q9NRA0
Processes and pathways
GO Biological process
msigdb_gobp
420,138,15,143,429,522,227
2502,590,15,1878,138,143,420,2178,1923,522,2394,227,429
-0.3265940252928932,0.5366787829519797,4.964849362308119,-0.098122333905974,1.623176179314646,1.5938382520831849,0.7531817696547146,-0.19560956934146895,-0.098122333905974,0.6298028841948623,-0.2609563355332265,1.2083001127798034,0.7531817696547146
3,643
Foot dorsiflexor weakness
9
33
2.433621
0.014949
Q9NR77,Q99720,Q9BQT8,Q7LG56,Q14739,P02545,P06753,P39210,P07196
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,2,577,464,416,265,394,267,125
2210,2049,746,2212,2504,791,265,2054,394,125,2711,267,2432,1800,2156,2242,1387,2349,2585,959,2529,416,566,2889,2363,1825,2946,464,2830,2,577,32,2960
-0.22824695247054547,-0.16304347134508207,0.4117022638315761,-0.22824695247054547,-0.3265940252928932,0.3803099800917596,1.0578712931665288,-0.16304347134508207,0.7838890695289682,1.7400910153055076,-0.42560918711049844,1.0578712931665288,-0.29373844618932715,-0.06576592628969985,-0.19560956934146895,-0.22824695247054547,0.09500082791205905,-0.2609563355332265,-0.3595238272390506,0.2857692407025649,-0.3265940252928932,0.7531817696547146,0.5677772700633923,-0.525313577596298,-0.2609563355332265,-0.06576592628969985,-0.5587053640309138,0.6916031594494587,-0.4920008457387619,8.21990109917503,0.5677772700633923,3.6085359292973544,-0.5587053640309138
3,643
Production of molecular mediator of immune response
14
41
2.431135
0.015052
Q9UQ84,P20585,Q96FV9,P02786,Q7Z434,P30511,Q9NQT5,P14174,Q01650,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0
Processes and pathways
GO Biological process
msigdb_gobp
33,309,681,409,420,138,638,15,143,590,87,429,522,227
2502,1217,87,409,590,2509,653,3256,3513,15,1878,309,1148,138,2229,1548,1553,1390,143,1727,2526,1404,2535,969,1737,420,1256,2178,1923,681,914,1928,3235,3479,522,638,2394,227,429,33,1692
-0.3265940252928932,0.15884550726049723,2.11542427763213,0.7531817696547146,0.5366787829519797,-0.3265940252928932,0.47430803058067816,-0.8287924672030076,-1.2798752825252815,4.964849362308119,-0.098122333905974,0.9670119136618348,0.19067127264620573,1.623176179314646,-0.22824695247054547,0.030894617027511038,0.030894617027511038,0.09500082791205905,1.5938382520831849,-0.03347806686168351,-0.3265940252928932,0.09500082791205905,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.7531817696547146,0.15884550726049723,-0.19560956934146895,-0.098122333905974,0.47430803058067816,0.31734400267200297,-0.098122333905974,-0.7947358122572576,-1.174345720866778,0.6298028841948623,0.5055225334229401,-0.2609563355332265,1.2083001127798034,0.7531817696547146,3.6085359292973544,-0.0012581004565036626
3,643
Regulation of response to external stimulus
37
150
2.425855
0.015272
P30511,P14174,Q9UMX5,Q96G23,P05067,P60900,P19474,Q06481,Q9BY67,P28070,Q7Z434,P80404,P00813,O75592,O43657,O94874,O14936,P55011,Q15046,Q15233,Q13641,P12956,Q13573,P78536,Q9BX67,P11274,P80303,Q9NUQ9,Q96RK4,P51809,Q9NZ08,Q9NWH9,O95219,P10586,Q99538,O75844,P23246
Processes and pathways
GO Biological process
msigdb_gobp
138,15,27,159,29,283,36,39,304,164,420,413,56,186,557,558,436,440,566,567,329,83,88,216,488,338,93,102,519,476,245,371,235,119,520,248,375
1605,1606,2050,436,2211,2502,557,2860,2794,1614,3496,2796,3216,186,248,749,1698,558,1616,235,2053,56,3617,1872,703,2508,590,29,1789,1457,1081,119,338,1082,83,1146,15,942,1794,2427,36,2337,375,2762,616,3322,2658,164,3197,2928,3198,138,2874,3520,2342,3297,756,890,2712,1630,3344,476,1632,1888,440,797,3546,283,3160,1156,1390,216,3038,93,413,1235,2258,2938,1815,39,1310,1394,1395,1727,1479,2672,88,329,2814,566,567,2531,1037,2271,1404,1097,856,3579,3042,1098,2946,1909,420,1323,3530,1743,859,1180,2949,973,2828,1111,2683,2100,159,2621,2109,1261,2624,519,1506,3176,3177,520,1117,1752,2294,919,3236,488,304,3479,3533,2552,989,102,371,1356,245,828,784,1358,3184,3098,27,1855,927,1692,1132,2496
-0.0012581004565036626,-0.0012581004565036626,-0.16304347134508207,0.7224199472328477,-0.22824695247054547,-0.3265940252928932,0.5677772700633923,-0.525313577596298,-0.4920008457387619,-0.0012581004565036626,-1.244601121096576,-0.4920008457387619,-0.7947358122572576,1.387215394486587,1.118191455601226,0.4117022638315761,-0.03347806686168351,0.5677772700633923,-0.0012581004565036626,1.1482768495977804,-0.16304347134508207,2.6800374279695216,-2.342454069604444,-0.098122333905974,0.44303477605405855,-0.3265940252928932,0.5366787829519797,3.6353042018995785,-0.06576592628969985,0.06298071889501843,0.2224334357534765,1.7982903969638317,0.9061816816409076,0.2224334357534765,2.172563346869744,0.19067127264620573,4.964849362308119,0.2857692407025649,-0.06576592628969985,-0.29373844618932715,3.3662912544280115,-0.2609563355332265,0.8145422833591529,-0.4587663248239629,0.5055225334229401,-0.8971691305719629,-0.3925286203228279,1.5055575321040489,-0.7607655898218467,-0.5587053640309138,-0.7607655898218467,1.623176179314646,-0.525313577596298,-1.315246174406957,-0.2609563355332265,-0.8629365633590367,0.4117022638315761,0.31734400267200297,-0.42560918711049844,-0.0012581004565036626,-0.931491220478586,0.6607309570482511,-0.0012581004565036626,-0.098122333905974,0.7224199472328477,0.3803099800917596,-1.421932600442622,1.027635769907882,-0.726880811724572,0.19067127264620573,0.09500082791205905,1.2382387072449188,-0.6257295573052645,2.0006717808585845,0.7531817696547146,0.15884550726049723,-0.22824695247054547,-0.5587053640309138,-0.06576592628969985,3.257840018273795,0.12695555655645674,0.09500082791205905,0.09500082791205905,-0.03347806686168351,0.06298071889501843,-0.3925286203228279,2.11542427763213,0.9366227945511973,-0.4920008457387619,0.5677772700633923,0.5677772700633923,-0.3265940252928932,0.25413257026133235,-0.22824695247054547,0.09500082791205905,0.2224334357534765,0.34885740302862467,-1.63783022894056,-0.6257295573052645,0.2224334357534765,-0.5587053640309138,-0.098122333905974,0.7531817696547146,0.12695555655645674,-1.3507131280591325,-0.03347806686168351,0.34885740302862467,0.19067127264620573,-0.5587053640309138,0.2857692407025649,-0.4920008457387619,0.2224334357534765,-0.3925286203228279,-0.16304347134508207,1.5350292358486646,-0.3595238272390506,-0.16304347134508207,0.15884550726049723,-0.3595238272390506,0.6298028841948623,0.06298071889501843,-0.726880811724572,-0.726880811724572,0.6298028841948623,0.2224334357534765,-0.03347806686168351,-0.22824695247054547,0.31734400267200297,-0.7947358122572576,0.6607309570482511,0.9973494401983068,-1.174345720866778,-1.3507131280591325,-0.3265940252928932,0.2857692407025649,1.9718833674139287,0.845141841466991,0.12695555655645674,1.1482768495977804,0.3803099800917596,0.4117022638315761,0.12695555655645674,-0.726880811724572,-0.6593637349435877,3.795309279757627,-0.06576592628969985,0.31734400267200297,-0.0012581004565036626,0.2224334357534765,-0.29373844618932715
3,643
Abnormality of the metaphysis
14
61
2.424188
0.015343
P16278,Q8WVQ1,Q96L58,Q9HC07,Q7RTS9,P48735,Q14739,O95831,Q13126,P51798,O75530,Q9Y366,P00813,Q96HY6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
155,423,303,405,11,339,416,47,20,460,86,290,56,384
834,2502,1865,1960,1005,86,1284,3288,1141,47,2651,56,1288,2055,3150,155,2337,2147,707,1973,2713,3557,339,1802,460,2434,2257,2937,1893,1815,1640,20,416,900,3389,1038,2364,2605,11,2458,1500,423,2612,2180,2183,384,303,728,3052,2195,405,1270,3096,3006,524,2956,1852,2400,744,290,3012
0.34885740302862467,-0.3265940252928932,-0.098122333905974,-0.13054795621506413,0.25413257026133235,2.11542427763213,0.12695555655645674,-0.8629365633590367,0.19067127264620573,3.0119856905575273,-0.3925286203228279,2.6800374279695216,0.12695555655645674,-0.16304347134508207,-0.726880811724572,1.5350292358486646,-0.2609563355332265,-0.19560956934146895,0.44303477605405855,-0.13054795621506413,-0.42560918711049844,-1.4935285643358234,0.9061816816409076,-0.06576592628969985,0.6916031594494587,-0.29373844618932715,-0.22824695247054547,-0.5587053640309138,-0.098122333905974,-0.06576592628969985,-0.0012581004565036626,4.39950530014643,0.7531817696547146,0.31734400267200297,-1.0004082879139022,0.25413257026133235,-0.2609563355332265,-0.3595238272390506,5.543953911878619,-0.29373844618932715,0.06298071889501843,0.7531817696547146,-0.3595238272390506,-0.19560956934146895,-0.19560956934146895,0.8145422833591529,0.9973494401983068,0.44303477605405855,-0.6257295573052645,-0.19560956934146895,0.7838890695289682,0.15884550726049723,-0.6593637349435877,-0.5921770650124923,0.6298028841948623,-0.5587053640309138,-0.06576592628969985,-0.2609563355332265,0.44303477605405855,1.027635769907882,-0.5921770650124923
3,643
Coxa vara
6
16
2.422851
0.015399
Q8WVQ1,Q9Y487,Q7RTS9,O75718,O95831,Q96HY6
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
423,43,11,295,47,384
2412,295,47,2147,1802,2434,2364,11,423,2612,1112,384,3052,524,3012,43
-0.29373844618932715,0.9973494401983068,3.0119856905575273,-0.19560956934146895,-0.06576592628969985,-0.29373844618932715,-0.2609563355332265,5.543953911878619,0.7531817696547146,-0.3595238272390506,0.2224334357534765,0.8145422833591529,-0.6257295573052645,0.6298028841948623,-0.5921770650124923,3.2306497156014906
3,643
Organic anion transmembrane transporter activity
17
37
2.422387
0.015419
P11166,Q86VD7,Q14728,O00400,O95563,Q9UBX3,Q9H2D1,P41440,Q9BQT8,P53985,Q8TB61,Q01650,Q15758,P30825,Q9HC21,Q9Y619,Q9Y6M7
Functions
GO Molecular function
msigdb_gomf
279,256,624,646,152,306,733,90,577,44,573,143,662,54,553,693,361
646,2793,1003,2754,1450,152,1873,704,279,2331,1145,54,2342,90,2073,44,143,2771,624,662,2274,2366,3456,256,1177,573,2906,2907,2292,577,733,1057,553,306,924,693,361
0.47430803058067816,-0.4920008457387619,0.25413257026133235,-0.4587663248239629,0.06298071889501843,1.5350292358486646,-0.098122333905974,0.44303477605405855,1.027635769907882,-0.2609563355332265,0.19067127264620573,2.707887319665007,-0.2609563355332265,2.058127752852981,-0.16304347134508207,3.1215736355280526,1.5938382520831849,-0.4587663248239629,0.5055225334229401,0.47430803058067816,-0.22824695247054547,-0.2609563355332265,-1.1393655482262741,1.08805639508316,0.19067127264620573,0.5677772700633923,-0.525313577596298,-0.525313577596298,-0.22824695247054547,0.5677772700633923,0.44303477605405855,0.25413257026133235,0.5988184783374502,0.9973494401983068,0.31734400267200297,0.47430803058067816,0.8756881681175116
3,643
Abnormality of femur morphology
22
76
2.416486
0.015671
O00116,Q7RTS9,P02545,P06280,P16278,Q9UHX1,Q8WVQ1,Q96L58,Q9Y487,O75718,Q14739,O95831,O00754,P55011,P07602,O75431,P51798,O75530,P11274,P04066,Q96HY6,O75844
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
374,11,265,153,155,171,423,303,43,295,416,47,435,440,69,213,460,86,338,228,384,248
374,834,3186,435,1210,585,1958,2412,213,86,295,248,1784,47,2651,265,703,228,1288,153,69,338,155,2145,2337,2147,3197,707,2764,3031,2933,3117,2713,1802,460,3626,1022,440,2434,416,900,806,1038,2728,2364,1905,2003,3413,11,2458,1664,1500,2610,423,2612,1048,1112,384,303,2185,3052,3001,3561,3003,3096,524,2034,3182,1064,1852,171,2041,3012,43,1069,693
0.8145422833591529,0.34885740302862467,-0.7607655898218467,0.7224199472328477,0.15884550726049723,0.5366787829519797,-0.13054795621506413,-0.29373844618932715,1.2382387072449188,2.11542427763213,0.9973494401983068,1.118191455601226,-0.06576592628969985,3.0119856905575273,-0.3925286203228279,1.0578712931665288,0.44303477605405855,1.1783129469800828,0.12695555655645674,1.5350292358486646,2.427791890653298,0.9061816816409076,1.5350292358486646,-0.19560956934146895,-0.2609563355332265,-0.19560956934146895,-0.7607655898218467,0.44303477605405855,-0.4587663248239629,-0.6257295573052645,-0.5587053640309138,-0.6930805097254553,-0.42560918711049844,-0.06576592628969985,0.6916031594494587,-2.919565762049335,0.25413257026133235,0.7224199472328477,-0.29373844618932715,0.7531817696547146,0.31734400267200297,0.3803099800917596,0.25413257026133235,-0.42560918711049844,-0.2609563355332265,-0.098122333905974,-0.13054795621506413,-1.0350054838275398,5.543953911878619,-0.29373844618932715,-0.0012581004565036626,0.06298071889501843,-0.3595238272390506,0.7531817696547146,-0.3595238272390506,0.25413257026133235,0.2224334357534765,0.8145422833591529,0.9973494401983068,-0.19560956934146895,-0.6257295573052645,-0.5921770650124923,-1.4935285643358234,-0.5921770650124923,-0.6593637349435877,0.6298028841948623,-0.13054795621506413,-0.726880811724572,0.25413257026133235,-0.06576592628969985,1.5055575321040489,-0.13054795621506413,-0.5921770650124923,3.2306497156014906,0.25413257026133235,0.47430803058067816
3,643
Negative regulation of cell population proliferation
23
112
2.411701
0.015878
P98175,O94788,Q71SY5,P02545,Q9Y366,Q96G23,P05067,Q9NR77,P22466,Q06481,Q15392,Q96DY7,Q13049,Q14457,Q96TA1,Q01664,Q13641,Q9Y4G8,P52756,P09493,P25705,P15291,P57105
Processes and pathways
GO Biological process
msigdb_gobp
134,9,144,265,290,159,29,32,38,39,45,61,188,189,333,327,329,81,210,215,237,112,238
3185,2134,2793,436,1774,2211,933,1611,350,2648,9,791,265,3291,1288,29,2055,215,653,2511,1377,112,3024,3570,2225,38,2064,237,2338,3615,2709,534,708,2229,2431,1296,1547,756,3325,849,210,3157,3345,238,3546,3120,1025,3038,134,1988,1560,327,2258,39,3080,1561,897,3620,2082,803,188,2168,2442,564,1562,1994,329,2267,1095,189,45,2725,1037,1404,3501,2728,1098,1171,2454,1909,144,2006,1108,1045,3173,2683,978,61,2619,159,1339,2621,333,3176,3235,2385,2687,1580,3561,489,2119,32,824,3431,582,3246,3184,1689,290,3248,81,555
-0.7607655898218467,-0.19560956934146895,-0.4920008457387619,0.7224199472328477,-0.06576592628969985,-0.22824695247054547,0.2857692407025649,-0.0012581004565036626,0.8756881681175116,-0.3925286203228279,5.816916168706705,0.3803099800917596,1.0578712931665288,-0.8629365633590367,0.12695555655645674,3.6353042018995785,-0.16304347134508207,1.2382387072449188,0.47430803058067816,-0.3265940252928932,0.09500082791205905,1.8563207862044178,-0.6257295573052645,-1.5654960467228805,-0.22824695247054547,3.257840018273795,-0.16304347134508207,1.1482768495977804,-0.2609563355332265,-2.2291720974867153,-0.42560918711049844,0.5988184783374502,0.44303477605405855,-0.22824695247054547,-0.29373844618932715,0.12695555655645674,0.030894617027511038,0.4117022638315761,-0.8971691305719629,0.34885740302862467,1.268129085929357,-0.726880811724572,-0.931491220478586,1.1482768495977804,-1.421932600442622,-0.6930805097254553,0.25413257026133235,-0.6257295573052645,1.6524701228970238,-0.13054795621506413,0.030894617027511038,0.9366227945511973,-0.22824695247054547,3.257840018273795,-0.6593637349435877,0.030894617027511038,0.31734400267200297,-2.3803772184572165,-0.16304347134508207,0.3803099800917596,1.387215394486587,-0.19560956934146895,-0.29373844618932715,0.5677772700633923,0.030894617027511038,-0.13054795621506413,0.9366227945511973,-0.22824695247054547,0.2224334357534765,1.387215394486587,3.1215736355280526,-0.42560918711049844,0.25413257026133235,0.09500082791205905,-1.244601121096576,-0.42560918711049844,0.2224334357534765,0.19067127264620573,-0.29373844618932715,-0.098122333905974,1.5938382520831849,-0.13054795621506413,0.2224334357534765,0.25413257026133235,-0.726880811724572,-0.3925286203228279,0.2857692407025649,2.5402599154147643,-0.3595238272390506,1.5350292358486646,0.12695555655645674,-0.3595238272390506,0.9366227945511973,-0.726880811724572,-0.7947358122572576,-0.2609563355332265,-0.3925286203228279,0.030894617027511038,-1.4935285643358234,0.6607309570482511,-0.16304347134508207,3.6085359292973544,0.3803099800917596,-1.069696640684267,0.5677772700633923,-0.7947358122572576,-0.726880811724572,-0.0012581004565036626,1.027635769907882,-0.7947358122572576,2.2579809707838456,0.5988184783374502
3,643
Tetrapyrrole binding
6
23
2.408938
0.015999
Q16850,O15173,P30519,O43169,Q8WUJ1,Q9NUN5
Functions
GO Molecular function
msigdb_gomf
67,199,14,263,49,123
932,199,263,2705,1618,653,2428,14,948,67,1492,286,49,724,1337,820,3561,2693,1193,492,1061,123,609
0.2857692407025649,1.327766595224347,1.0578712931665288,-0.42560918711049844,-0.0012581004565036626,0.47430803058067816,-0.29373844618932715,5.1928477731586264,0.2857692407025649,2.4559635740626335,0.06298071889501843,1.027635769907882,2.9569963157150747,0.44303477605405855,0.12695555655645674,0.3803099800917596,-1.4935285643358234,-0.3925286203228279,0.19067127264620573,0.6607309570482511,0.25413257026133235,1.7692119702003737,0.5366787829519797
3,643
Membrane invagination
7
17
2.40777
0.01605
P35579,Q06481,P84095,Q9Y5X1,P51790,Q14457,Q14185
Processes and pathways
GO Biological process
msigdb_gobp
280,39,139,107,459,189,94
1774,2963,1213,942,280,459,476,1723,1156,139,39,3348,94,189,3042,1925,107
-0.06576592628969985,-0.5921770650124923,0.15884550726049723,0.2857692407025649,1.027635769907882,0.6916031594494587,0.6607309570482511,-0.03347806686168351,0.19067127264620573,1.623176179314646,3.257840018273795,-0.931491220478586,2.0006717808585845,1.387215394486587,-0.6257295573052645,-0.098122333905974,1.943054324684516
3,643
Regulation of immune effector process
19
54
2.402645
0.016277
Q96FV9,P30511,P14174,Q01650,Q9NY93,Q9BY67,Q06481,P02786,Q7Z434,P04439,O96028,O15400,P11274,Q9NRA0,Q9NUQ9,P51809,Q9NQT5,O95219,Q9H2U1
Processes and pathways
GO Biological process
msigdb_gobp
681,138,15,143,429,304,39,409,420,590,87,586,338,227,102,476,638,235,522
586,2502,2860,2796,235,87,1872,409,2508,590,2509,1081,653,3256,338,1082,15,1084,1878,138,3520,2229,3297,1548,2712,476,143,39,1310,1395,1727,2526,2532,1404,2535,969,1737,420,2178,2377,1923,681,914,1928,3235,304,3479,522,638,2394,227,102,429,3098
0.5366787829519797,-0.3265940252928932,-0.525313577596298,-0.4920008457387619,1.1482768495977804,2.11542427763213,-0.098122333905974,0.7531817696547146,-0.3265940252928932,0.5366787829519797,-0.3265940252928932,0.2224334357534765,0.47430803058067816,-0.8287924672030076,0.9061816816409076,0.2224334357534765,4.964849362308119,0.2224334357534765,-0.098122333905974,1.623176179314646,-1.315246174406957,-0.22824695247054547,-0.8629365633590367,0.030894617027511038,-0.42560918711049844,0.6607309570482511,1.5938382520831849,3.257840018273795,0.12695555655645674,0.09500082791205905,-0.03347806686168351,-0.3265940252928932,-0.3265940252928932,0.09500082791205905,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.7531817696547146,-0.19560956934146895,-0.2609563355332265,-0.098122333905974,0.47430803058067816,0.31734400267200297,-0.098122333905974,-0.7947358122572576,0.9973494401983068,-1.174345720866778,0.6298028841948623,0.5055225334229401,-0.2609563355332265,1.2083001127798034,1.9718833674139287,0.7531817696547146,-0.6593637349435877
3,643
Proteasome, subunit alpha/beta [IPR001353]
6
14
2.400558
0.01637
P28070,P28074,P20618,P28072,Q99436,P49721
Sequence
InterPro Family
interpro_family
164,41,137,146,121,60
3142,137,2762,1461,1621,2802,3222,164,146,41,2878,60,283,121
-0.726880811724572,1.623176179314646,-0.4587663248239629,0.06298071889501843,-0.0012581004565036626,-0.4920008457387619,-0.7947358122572576,1.5055575321040489,1.5644560394229112,3.2306497156014906,-0.525313577596298,2.5402599154147643,1.027635769907882,1.7692119702003737
3,643
Shoulder girdle muscle weakness
7
17
2.399971
0.016396
P07602,Q8TD16,Q7LG56,P06753,Q9H9S5,Q96RR1,Q13049
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
69,272,464,394,347,319,188
1000,2136,394,69,2331,890,2432,2242,2349,188,477,464,272,319,347,1064,1604
0.25413257026133235,-0.19560956934146895,0.7838890695289682,2.427791890653298,-0.2609563355332265,0.31734400267200297,-0.29373844618932715,-0.22824695247054547,-0.2609563355332265,1.387215394486587,0.6607309570482511,0.6916031594494587,1.0578712931665288,0.9670119136618348,0.9061816816409076,0.25413257026133235,0.030894617027511038
3,643
Developmental maturation
7
44
2.393976
0.016667
Q8N2A8,P22466,O94788,P07196,Q12834,O75503,P05067
Processes and pathways
GO Biological process
msigdb_gobp
68,38,9,125,284,24,29
2792,999,2860,1864,2796,24,296,9,703,3255,29,125,1080,2143,840,3436,3406,2925,38,1968,708,3035,2713,1301,459,2437,1396,801,284,2596,1166,1899,1245,718,3169,2607,68,1328,3427,1933,1064,1853,452,2496
-0.4920008457387619,0.25413257026133235,-0.525313577596298,-0.098122333905974,-0.4920008457387619,4.11230346222967,0.9973494401983068,5.816916168706705,0.44303477605405855,-0.8287924672030076,3.6353042018995785,1.7400910153055076,0.2224334357534765,-0.19560956934146895,0.34885740302862467,-1.104482929673742,-1.0350054838275398,-0.5587053640309138,3.257840018273795,-0.13054795621506413,0.44303477605405855,-0.6257295573052645,-0.42560918711049844,0.12695555655645674,0.6916031594494587,-0.29373844618932715,0.09500082791205905,0.3803099800917596,1.027635769907882,-0.3595238272390506,0.19067127264620573,-0.098122333905974,0.15884550726049723,0.44303477605405855,-0.726880811724572,-0.3595238272390506,2.4559635740626335,0.12695555655645674,-1.069696640684267,-0.098122333905974,0.25413257026133235,-0.06576592628969985,0.7224199472328477,-0.29373844618932715
3,643
Dysostosis multiplex
6
8
2.393415
0.016692
P16278,O00754,P04066,P15586,P54802,P10619
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
155,435,228,410,147,59
435,228,455,59,410,155,147,2180
0.7224199472328477,1.1783129469800828,0.6916031594494587,2.5402599154147643,0.7531817696547146,1.5350292358486646,1.5644560394229112,-0.19560956934146895
3,643
Intrinsic component of organelle membrane
55
149
2.380307
0.017298
Q86XL3,O15118,Q9P2E9,O96008,Q15629,P30511,Q8N2H4,Q99595,Q7L0J3,Q13505,Q99442,Q9HCU5,O75298,Q9Y5Z9,Q8TCT8,Q9HC21,Q9UBM7,O95563,Q8N4V1,P10321,Q9UH99,Q9NWR8,Q86UP2,Q8TB61,Q14739,Q15070,P42892,Q9BPX6,Q9BUB7,Q969N2,Q5H8A4,P50336,Q5SNT2,Q9Y282,Q16891,O60499,Q9H3K2,O43505,Q9Y2U8,Q9Y4W6,Q6P4A7,O43752,O75431,P61020,P04439,O95070,O95470,Q9Y2R0,Q9NX63,Q5T9L3,Q9H4I9,P57105,Q9NXW2,O75844,Q9GZY8
Localization
GO Cellular component
msigdb_gocc
513,252,407,500,509,138,672,682,17,19,547,687,393,291,158,553,289,152,167,532,170,305,301,573,416,417,53,320,447,318,569,313,442,193,568,196,734,205,744,608,719,454,213,596,590,700,701,219,494,767,244,238,782,248,130
1206,2751,1772,1954,252,1073,1695,2216,2858,205,454,2754,2504,196,2795,393,213,248,1285,881,2326,1698,3102,700,791,701,152,500,1872,590,3497,532,2331,2332,1015,2578,2658,1711,3030,138,3031,53,313,3264,2156,1887,2351,238,596,2807,1477,2812,1028,1159,2527,19,1484,416,962,1317,417,902,1649,509,2774,3501,568,905,3581,569,3474,442,767,1491,3045,719,1173,809,971,17,301,513,810,1176,3275,1177,2462,2007,672,167,2994,1498,1664,2949,573,158,3492,2012,1921,318,3231,1048,3634,2543,2906,2020,547,682,320,2688,1581,447,3056,3553,2114,130,734,244,1057,2118,553,687,1193,2392,1847,2844,1355,305,494,782,2488,2847,3007,407,289,2400,3062,170,1593,2959,193,219,744,874,1603,608,786,291,995
0.15884550726049723,-0.4587663248239629,-0.06576592628969985,-0.13054795621506413,1.08805639508316,0.2224334357534765,-0.03347806686168351,-0.22824695247054547,-0.525313577596298,1.2979715997804608,0.6916031594494587,-0.4587663248239629,-0.3265940252928932,1.3575144142492008,-0.4920008457387619,0.7838890695289682,1.2382387072449188,1.118191455601226,0.12695555655645674,0.31734400267200297,-0.2609563355332265,-0.03347806686168351,-0.6930805097254553,0.44303477605405855,0.3803099800917596,0.44303477605405855,1.5350292358486646,0.6298028841948623,-0.098122333905974,0.5366787829519797,-1.244601121096576,0.5988184783374502,-0.2609563355332265,-0.2609563355332265,0.25413257026133235,-0.3595238272390506,-0.3925286203228279,-0.03347806686168351,-0.6257295573052645,1.623176179314646,-0.6257295573052645,2.763483088965262,0.9670119136618348,-0.8287924672030076,-0.19560956934146895,-0.098122333905974,-0.2609563355332265,1.1482768495977804,0.5366787829519797,-0.4920008457387619,0.06298071889501843,-0.4920008457387619,0.25413257026133235,0.19067127264620573,-0.3265940252928932,4.451389856938803,0.06298071889501843,0.7531817696547146,0.2857692407025649,0.12695555655645674,0.7531817696547146,0.31734400267200297,-0.0012581004565036626,0.6298028841948623,-0.4587663248239629,-1.244601121096576,0.5677772700633923,0.31734400267200297,-1.63783022894056,0.5677772700633923,-1.174345720866778,0.7224199472328477,0.4117022638315761,0.06298071889501843,-0.6257295573052645,0.44303477605405855,0.19067127264620573,0.3803099800917596,0.2857692407025649,4.734981990697083,0.9973494401983068,0.6298028841948623,0.3803099800917596,0.19067127264620573,-0.8287924672030076,0.19067127264620573,-0.29373844618932715,-0.13054795621506413,0.47430803058067816,1.5055575321040489,-0.5921770650124923,0.06298071889501843,-0.0012581004565036626,-0.5587053640309138,0.5677772700633923,1.5350292358486646,-1.209424370050621,-0.13054795621506413,-0.098122333905974,0.9670119136618348,-0.7947358122572576,0.25413257026133235,-4.5798467158688725,-0.3265940252928932,-0.525313577596298,-0.13054795621506413,0.5988184783374502,0.47430803058067816,0.9670119136618348,-0.3925286203228279,0.030894617027511038,0.7224199472328477,-0.6257295573052645,-1.4576838354723742,-0.16304347134508207,1.7109272480905777,0.44303477605405855,1.1482768495977804,0.25413257026133235,-0.16304347134508207,0.5988184783374502,0.47430803058067816,0.19067127264620573,-0.2609563355332265,-0.06576592628969985,-0.4920008457387619,0.12695555655645674,0.9973494401983068,0.6607309570482511,0.4117022638315761,-0.29373844618932715,-0.4920008457387619,-0.5921770650124923,0.7838890695289682,1.027635769907882,-0.2609563355332265,-0.6257295573052645,1.5055575321040489,0.030894617027511038,-0.5587053640309138,1.387215394486587,1.2382387072449188,0.44303477605405855,0.34885740302862467,0.030894617027511038,0.5366787829519797,0.4117022638315761,1.027635769907882,0.2857692407025649
3,643
serine protease
7
19
2.376862
0.017461
Q9H3G5,Q9HB40,P42785,Q4J6C6,Q16740,O14773,P10619
Functions
Panther Protein class
panther_protein_class
359,35,4,135,113,391,59
391,59,3220,3109,2659,1973,4,3201,2254,113,1652,135,2005,2989,859,491,359,35,3464
0.7838890695289682,2.5402599154147643,-0.7947358122572576,-0.6930805097254553,-0.3925286203228279,-0.13054795621506413,6.233993929662534,-0.7607655898218467,-0.22824695247054547,1.8563207862044178,-0.0012581004565036626,1.6524701228970238,-0.13054795621506413,-0.5921770650124923,0.34885740302862467,0.6607309570482511,0.8756881681175116,3.447308651903207,-1.1393655482262741
3,643
Regulation of b cell activation
6
19
2.375492
0.017526
P02786,Q9NQT5,P14174,Q9NPF0,P00813,O96028
Processes and pathways
GO Biological process
msigdb_gobp
409,638,15,492,56,87
2410,87,56,409,15,1548,2526,1404,1100,2535,969,1737,681,914,1339,1928,492,638,2788
-0.29373844618932715,2.11542427763213,2.6800374279695216,0.7531817696547146,4.964849362308119,0.030894617027511038,-0.3265940252928932,0.09500082791205905,0.2224334357534765,-0.3265940252928932,0.2857692407025649,-0.03347806686168351,0.47430803058067816,0.31734400267200297,0.12695555655645674,-0.098122333905974,0.6607309570482511,0.5055225334229401,-0.4587663248239629
3,643