term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coated vesicle
| 28
| 89
| 3.216053
| 0.0013
|
P24390,P02786,P51572,Q14108,Q15363,Q9Y3B3,O43731,P49755,O00165,Q8N511,Q9Y5X1,Q9BVK6,P55735,P05067,O15126,Q5VW38,P10321,Q9Y6Y8,Q9Y282,P42892,Q13190,Q12907,O00443,P53634,P04439,O95782,Q9UBR2,Q9Y3A6
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,265,141,14,29,30,36,417,45,49,308,444,440,438,436,68,455,476,85,91,354,490,350,487,233,485,244,513
|
45,1313,1883,350,2635,798,1394,436,36,1705,2222,2137,1355,1574,2764,2447,1194,942,485,1497,265,233,438,1990,455,3129,2354,568,1945,633,2,990,91,1069,867,417,777,1454,141,1360,2504,2267,487,1584,2321,440,1901,1247,657,2747,1625,1906,490,354,2689,14,1512,783,29,998,693,1465,2328,68,1211,49,819,1344,444,666,1221,822,1057,523,1224,720,1565,1933,244,2978,2923,1603,2028,85,513,30,308,710,476
|
2.832792341598909,0.0566926794738131,-0.26419124276665046,1.0543605595517835,-0.7452104629394918,0.40652433044515934,0.009638014956759703,0.8907287812193003,2.96913415144942,-0.16155054834083413,-0.4529950413267082,-0.39780592754705757,0.03326476765043723,-0.08691226787820137,-0.8703399800828923,-0.5955921179420027,0.12580968009238108,0.30200233977580343,0.8045775073895869,-0.03822288271037234,1.3648314259575298,1.446271558144171,0.8907287812193003,-0.31690808027229783,0.8566305867164241,-1.7850748625508288,-0.5377405503528547,0.6786968138424812,-0.2904304927178063,0.5847653265563068,3.7462657069794476,0.259018664523886,2.359178009634381,0.21533758545793177,0.36520852896444506,0.9243562959106226,0.42694183408394704,-0.014190283332690111,1.9223825076951602,0.03326476765043723,-0.6249367779380635,-0.4809780479553145,0.8045775073895869,-0.08691226787820137,-0.5092252179873332,0.8907287812193003,-0.26419124276665046,0.10296255264400622,0.5655565678430635,-0.8385853324054076,-0.11157482962869282,-0.26419124276665046,0.8045775073895869,1.0543605595517835,-0.7760255732552376,3.309160878702859,-0.03822288271037234,0.42694183408394704,3.078186020550252,0.259018664523886,0.5267030007716262,-0.014190283332690111,-0.5092252179873332,2.5972531017791676,0.12580968009238108,2.7869149799952893,0.40652433044515934,0.0566926794738131,0.8907287812193003,0.5655565678430635,0.12580968009238108,0.40652433044515934,0.23726642403703146,0.7514043268649677,0.12580968009238108,0.48725623745593405,-0.062462590653624604,-0.26419124276665046,1.4329036514563958,-1.1713430341599453,-1.0678476456651755,-0.08691226787820137,-0.31690808027229783,2.4339675988258307,0.7692555416447295,3.067058131253242,1.207423100369303,0.5070546681307051,0.8394016868466264
| 3,193
|
Membrane lipid biosynthetic process
| 11
| 20
| 3.211961
| 0.001318
|
Q06136,Q9P035,O95470,Q9H490,Q16880,Q99805,O15269,Q8NBX0,Q13510,P04062,Q96G23
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,524,171,368,273,367,303,21,116,122,159
|
303,1060,1166,171,122,1847,99,116,273,1295,21,519,1683,159,1971,367,368,707,524,2256
|
1.207423100369303,0.21533758545793177,0.1484683010782358,1.744645033106282,2.153135324237049,-0.23818692761586824,2.3075717767503545,2.1998773817605315,1.3370121237135937,0.07992440556882748,3.148622465340775,0.7514043268649677,-0.13645324700708894,1.8243030426289284,-0.2904304927178063,1.0225160037257737,1.0225160037257737,0.5070546681307051,0.7514043268649677,-0.4529950413267082
| 3,193
|
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
| 11
| 28
| 3.206624
| 0.001343
|
Q9H4A6,P24390,O43731,P49755,Q12981,Q12893,P84085,Q9P2W9,O15258,Q9Y282,P42858
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
426,2,36,417,420,325,458,100,351,85,341
|
1352,2635,351,36,1574,1169,2,990,341,1069,1241,417,2267,657,833,458,325,490,420,737,1118,1259,1215,426,1183,100,1933,85
|
0.03326476765043723,-0.7452104629394918,1.0543605595517835,2.96913415144942,-0.08691226787820137,0.1484683010782358,3.7462657069794476,0.259018664523886,1.1013384647454063,0.21533758545793177,0.10296255264400622,0.9243562959106226,-0.4809780479553145,0.5655565678430635,0.38594722827302785,0.8566305867164241,1.1321439407679112,0.8045775073895869,0.9243562959106226,0.46730587199900714,0.19322985148629535,0.10296255264400622,0.12580968009238108,0.9243562959106226,0.1484683010782358,2.3075717767503545,-0.26419124276665046,2.4339675988258307
| 3,193
|
Glycoprotein metabolic process
| 24
| 56
| 3.205769
| 0.001347
|
Q7LGA3,Q13724,O60476,O43505,Q9HC07,P62820,P35610,Q9H4A6,Q96L58,Q6ZXV5,Q86YN1,O60502,Q9Y5P6,Q8WVQ1,Q9BT22,Q2TAA5,Q92542,Q9BV10,P46977,Q8NCH0,Q9NQX7,Q10471,Q16706,Q99805
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,517,398,275,146,531,288,426,291,559,177,52,445,311,316,326,329,199,206,82,106,489,362,367
|
2605,2086,966,858,2394,3012,275,398,52,1396,1166,1355,2089,687,1030,2188,1502,288,1896,206,713,531,833,1667,1909,489,517,872,1726,362,326,559,131,1765,177,82,587,311,329,291,3098,367,2025,316,199,1973,961,1222,426,146,106,1643,1483,1696,445,3160
|
-0.7146987125093559,-0.37059222129993374,0.28059656391052684,0.36520852896444506,-0.5665281275626076,-1.2782188724392092,1.3229726085415559,0.9575234066599015,2.7397396070190534,0.009638014956759703,0.1484683010782358,0.03326476765043723,-0.37059222129993374,0.5267030007716262,0.23726642403703146,-0.4252722805882104,-0.03822288271037234,1.280324185022697,-0.26419124276665046,1.5503857345605445,0.48725623745593405,0.7334243460639536,0.38594722827302785,-0.13645324700708894,-0.26419124276665046,0.8045775073895869,0.7514043268649677,0.36520852896444506,-0.16155054834083413,1.0384916258428032,1.1321439407679112,0.6970721128067479,1.985222235335816,-0.18686982059176915,1.7095511162040427,2.4420909128633217,0.6601866548649779,1.1925614229636166,1.1321439407679112,1.2659284528512882,-1.5417758052175927,1.0225160037257737,-0.31690808027229783,1.1776036696350574,1.6130128562407051,-0.2904304927178063,0.30200233977580343,0.12580968009238108,0.9243562959106226,1.9009921408923331,2.263445511133267,-0.11157482962869282,-0.014190283332690111,-0.13645324700708894,0.8907287812193003,-2.1379443966160254
| 3,193
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 15
| 32
| 3.192339
| 0.001411
|
O75845,Q9BU89,Q15800,P30519,O00767,Q9NWT6,P16435,Q8NB78,P13674,P09601,Q32P28,Q14534,O95864,Q6UW02,Q16850
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
224,520,35,69,360,564,299,78,555,17,432,403,374,189,158
|
2605,360,1442,1940,1396,620,224,374,1652,17,555,299,69,1712,1902,1667,1365,403,35,158,432,1763,1515,189,2158,1963,78,520,2385,564,2491,2391
|
-0.7146987125093559,1.0384916258428032,-0.014190283332690111,-0.2904304927178063,0.009638014956759703,0.6038310370230041,1.4858962903240147,1.006432544850282,-0.13645324700708894,3.250973747172662,0.6970721128067479,1.2368621349000533,2.589810382359061,-0.16155054834083413,-0.26419124276665046,-0.13645324700708894,0.03326476765043723,0.9575234066599015,2.975065555239934,1.8243030426289284,0.9076007240012801,-0.18686982059176915,-0.03822288271037234,1.661830514045592,-0.39780592754705757,-0.2904304927178063,2.5057902110255577,0.7514043268649677,-0.5377405503528547,0.6970721128067479,-0.5955921179420027,-0.5377405503528547
| 3,193
|
Glycosaminoglycan metabolism
| 8
| 12
| 3.186849
| 0.001438
|
Q96L58,Q7LGA3,Q8TB61,P54802,P06865,P16278,Q8NCH0,O43505
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
291,131,101,166,293,11,82,275
|
2031,275,293,726,310,11,166,131,82,101,291,1696
|
-0.3436274762646461,1.3229726085415559,1.2514414118114898,0.46730587199900714,1.1925614229636166,3.418959561273887,1.7791593908234755,1.985222235335816,2.4420909128633217,2.2988294808347165,1.2659284528512882,-0.13645324700708894
| 3,193
|
Hydrolase activity hydrolyzing o glycosyl compounds
| 11
| 19
| 3.172486
| 0.001511
|
P54802,P10253,P06865,P06280,P16278,Q16706,P17900,O60476,O60502,P04062,Q9BTY2
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
166,102,293,298,11,362,234,398,52,122,250
|
2086,398,52,122,400,298,293,726,102,11,234,1358,166,517,1726,362,2756,250,793
|
-0.37059222129993374,0.9575234066599015,2.7397396070190534,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,0.46730587199900714,2.2900460179099036,3.418959561273887,1.446271558144171,0.03326476765043723,1.7791593908234755,0.7514043268649677,-0.16155054834083413,1.0384916258428032,-0.8385853324054076,1.4059236947909328,0.42694183408394704
| 3,193
|
Transporter
| 74
| 182
| 3.168699
| 0.001531
|
Q15043,P08183,P24390,Q9UI14,Q9BQE5,Q9Y5L0,Q8TAG9,Q93050,Q8TEX9,P28288,P51572,O95721,Q9Y6C9,Q9HC07,Q9HC21,P61619,Q9Y6M7,Q15388,O75746,O95202,Q00765,Q15363,Q9Y3B3,Q9UJS0,Q9H2J7,O43731,O43772,P49755,P56385,O15400,P53985,O75027,P16615,Q9H2V7,Q9H2D1,Q15070,Q70HW3,P24539,Q9UBX3,Q8N2H4,P11279,Q9BVK6,P55735,Q92544,Q9NZJ7,Q99808,Q9Y487,Q96ES6,P13473,P52292,Q9BXP2,P12235,Q9BSK2,P61421,P12236,Q9HD45,O95249,Q13190,Q9P2W9,Q8TB61,Q12907,O60499,Q8TAD4,Q9Y619,Q9BQT8,Q7L0J3,P17900,P05141,Q03518,Q99805,Q8IXU6,Q9Y3A6,O43760,O43808
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
256,129,2,525,6,397,518,138,395,515,141,399,144,146,405,530,151,280,527,155,546,29,30,428,289,36,162,417,418,413,169,170,300,174,47,48,50,181,54,182,309,444,440,315,191,321,71,75,204,333,475,338,212,466,217,90,348,354,100,101,490,103,105,239,238,108,234,361,111,367,117,513,125,505
|
2345,2604,1313,1314,685,1745,2635,1274,798,413,36,125,162,505,103,1131,2637,1132,2137,170,1133,527,2671,2447,155,348,2496,1194,942,399,651,712,2449,361,1134,129,727,1990,863,309,338,217,204,300,234,580,1846,2639,2,181,1997,515,1893,888,990,1797,2544,2864,654,1069,1241,867,417,141,1360,333,2721,730,2504,2267,1584,169,2321,1854,2004,2547,636,440,1199,545,418,1800,466,530,657,2747,994,1111,1625,546,870,111,1910,1250,623,1407,490,354,2689,1548,2415,2693,256,48,2156,2157,29,280,899,1921,1112,954,50,108,1730,627,117,586,182,1002,105,518,101,1865,395,1966,1259,315,931,138,787,819,1924,75,588,677,977,1522,845,367,321,6,238,2522,212,2071,444,475,1973,1221,47,289,174,1599,879,146,405,90,2808,191,2632,2256,720,100,1933,2178,54,1980,525,1646,428,855,1700,986,513,30,71,397,239,710,144,151
|
-0.5377405503528547,-0.7146987125093559,0.0566926794738131,0.0566926794738131,0.5267030007716262,-0.18686982059176915,-0.7452104629394918,0.07992440556882748,0.40652433044515934,0.9243562959106226,2.96913415144942,2.09550477869399,1.7905380137060627,0.7692555416447295,2.2812210779922095,0.17094088359372295,-0.7452104629394918,0.17094088359372295,-0.39780592754705757,1.744645033106282,0.17094088359372295,0.7334243460639536,-0.7760255732552376,-0.5955921179420027,1.8243030426289284,1.070123936480939,-0.6249367779380635,0.12580968009238108,0.30200233977580343,0.9575234066599015,0.5655565678430635,0.48725623745593405,-0.5955921179420027,1.0384916258428032,0.17094088359372295,2.0361169935164405,0.46730587199900714,-0.31690808027229783,0.36520852896444506,1.1925614229636166,1.1013384647454063,1.5248183397306079,1.5630573692038123,1.2368621349000533,1.446271558144171,0.6601866548649779,-0.23818692761586824,-0.7452104629394918,3.7462657069794476,1.6858254775131012,-0.31690808027229783,0.7514043268649677,-0.26419124276665046,0.3443061993948582,0.259018664523886,-0.21241421080737602,-0.6545664545020534,-1.00064563472387,0.5655565678430635,0.21533758545793177,0.10296255264400622,0.36520852896444506,0.9243562959106226,1.9223825076951602,0.03326476765043723,1.1167917984678513,-0.8071488815311059,0.46730587199900714,-0.6249367779380635,-0.4809780479553145,-0.08691226787820137,1.7677180561785404,-0.5092252179873332,-0.23818692761586824,-0.31690808027229783,-0.6545664545020534,0.5847653265563068,0.8907287812193003,0.12580968009238108,0.7153141117668748,0.9243562959106226,-0.21241421080737602,0.8394016868466264,0.7334243460639536,0.5655565678430635,-0.8385853324054076,0.259018664523886,0.19322985148629535,-0.11157482962869282,0.7153141117668748,0.36520852896444506,2.2364631467360248,-0.26419124276665046,0.10296255264400622,0.6038310370230041,0.009638014956759703,0.8045775073895869,1.0543605595517835,-0.7760255732552376,-0.062462590653624604,-0.5665281275626076,-0.7760255732552376,1.392310058750564,2.800152733484291,-0.39780592754705757,-0.39780592754705757,3.078186020550252,1.3088453672804772,0.3443061993948582,-0.26419124276665046,0.19322985148629535,0.30200233977580343,2.760120300435202,2.245500235348313,-0.16155054834083413,0.6038310370230041,2.1906198942531567,0.6601866548649779,1.6858254775131012,0.259018664523886,2.2812210779922095,0.7514043268649677,2.2988294808347165,-0.23818692761586824,0.9739374379111466,-0.2904304927178063,0.10296255264400622,1.1776036696350574,0.32323817115644027,1.9329933181047383,0.42694183408394704,0.40652433044515934,-0.26419124276665046,2.5291039002629425,0.6601866548649779,0.5462030417796385,0.28059656391052684,-0.03822288271037234,0.38594722827302785,1.0225160037257737,1.1473959441543768,3.5925647235517952,1.446271558144171,-0.6249367779380635,1.5376396248754793,-0.3436274762646461,0.8907287812193003,0.8394016868466264,-0.2904304927178063,0.12580968009238108,2.813285883739657,1.280324185022697,1.7330122185385242,-0.08691226787820137,0.36520852896444506,1.9009921408923331,0.9575234066599015,2.376064301841973,-0.902417991440706,1.6497305064842487,-0.7146987125093559,-0.4529950413267082,0.48725623745593405,2.3075717767503545,-0.26419124276665046,-0.39780592754705757,2.732890881137026,-0.2904304927178063,0.7514043268649677,-0.11157482962869282,0.9243562959106226,0.38594722827302785,-0.13645324700708894,0.28059656391052684,0.7692555416447295,3.067058131253242,2.582335824717171,0.9739374379111466,1.446271558144171,0.5070546681307051,1.9117156067218775,1.8465093473865353
| 3,193
|
Glycosphingolipid metabolism
| 10
| 17
| 3.16039
| 0.001576
|
P07602,P06865,P16278,P17900,Q16880,Q13510,Q8NBJ7,P04062,P10619,Q9NZJ7
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
72,293,11,234,273,116,56,122,127,191
|
617,619,122,298,293,72,726,127,2891,11,234,116,273,56,2120,707,191
|
0.6038310370230041,0.6038310370230041,2.153135324237049,1.2368621349000533,1.2514414118114898,2.5672903217950718,0.46730587199900714,2.0857311239846426,-1.034071137875609,3.418959561273887,1.446271558144171,2.1998773817605315,1.3370121237135937,2.69120665946763,-0.37059222129993374,0.5070546681307051,1.6497305064842487
| 3,193
|
Transport vesicle membrane
| 21
| 45
| 3.15264
| 0.001618
|
Q9NR31,P62820,Q15363,Q9Y3B3,P49755,Q15907,Q15437,P55735,O15126,P10321,O76024,P20020,Q9Y6Y8,Q13190,O60499,Q7L0J3,Q86Y82,O95782,P04439,O75592,O43760
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
523,531,29,30,417,306,693,440,436,455,454,580,476,354,103,108,627,485,233,620,125
|
1098,798,1394,436,1705,125,103,2137,1355,1574,620,454,2447,686,1194,942,485,1497,233,1990,455,580,1945,867,417,1287,1360,2321,440,1666,531,1625,354,783,29,998,693,306,108,627,1378,523,2978,30,476
|
0.19322985148629535,0.40652433044515934,0.009638014956759703,0.8907287812193003,-0.16155054834083413,2.09550477869399,2.2812210779922095,-0.39780592754705757,0.03326476765043723,-0.08691226787820137,0.6038310370230041,0.8566305867164241,-0.5955921179420027,0.5267030007716262,0.12580968009238108,0.30200233977580343,0.8045775073895869,-0.03822288271037234,1.446271558144171,-0.31690808027229783,0.8566305867164241,0.6601866548649779,-0.2904304927178063,0.36520852896444506,0.9243562959106226,0.07992440556882748,0.03326476765043723,-0.5092252179873332,0.8907287812193003,-0.13645324700708894,0.7334243460639536,-0.11157482962869282,1.0543605595517835,0.42694183408394704,3.078186020550252,0.259018664523886,0.5267030007716262,1.207423100369303,2.245500235348313,0.6038310370230041,0.03326476765043723,0.7514043268649677,-1.1713430341599453,3.067058131253242,0.8394016868466264
| 3,193
|
Copii coated er to golgi transport vesicle
| 15
| 31
| 3.141267
| 0.001682
|
Q13190,P49755,Q12907,P10321,P53634,Q9Y6Y8,P04439,Q9UBR2,Q9Y282,Q9BVK6,P55735,Q9Y3A6,P05067,Q15363,Q9Y3B3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
354,417,490,455,487,476,233,244,85,444,440,513,438,29,30
|
798,1394,2137,1355,1574,2447,1194,942,1497,233,438,455,867,417,487,2321,440,490,354,29,998,693,1211,444,523,244,2978,85,513,30,476
|
0.40652433044515934,0.009638014956759703,-0.39780592754705757,0.03326476765043723,-0.08691226787820137,-0.5955921179420027,0.12580968009238108,0.30200233977580343,-0.03822288271037234,1.446271558144171,0.8907287812193003,0.8566305867164241,0.36520852896444506,0.9243562959106226,0.8045775073895869,-0.5092252179873332,0.8907287812193003,0.8045775073895869,1.0543605595517835,3.078186020550252,0.259018664523886,0.5267030007716262,0.12580968009238108,0.8907287812193003,0.7514043268649677,1.4329036514563958,-1.1713430341599453,2.4339675988258307,0.7692555416447295,3.067058131253242,0.8394016868466264
| 3,193
|
Transition metal ion transport
| 7
| 14
| 3.140923
| 0.001684
|
Q15043,P02786,O75027,Q8TAD4,O15173,Q9HC07,Q9HD20
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
256,265,170,105,76,146,87
|
76,170,265,777,994,1625,2008,256,306,105,1383,879,146,87
|
2.5057902110255577,1.744645033106282,1.3648314259575298,0.42694183408394704,0.259018664523886,-0.11157482962869282,-0.31690808027229783,1.392310058750564,1.207423100369303,2.2812210779922095,0.03326476765043723,0.36520852896444506,1.9009921408923331,2.4176108705977826
| 3,193
|
Inorganic anion transport
| 11
| 27
| 3.136132
| 0.001712
|
P08183,P21796,Q9NW15,Q9C0H2,P45880,Q9Y277,Q9UBX3,Q9Y6M7,P30536,Q9UHG3,P51798
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,7,168,13,15,247,54,151,58,59,184
|
2964,619,129,3092,7,58,888,15,3156,184,1854,636,1111,870,256,1921,929,474,475,13,1928,168,54,59,247,2443,151
|
-1.1713430341599453,0.6038310370230041,2.0361169935164405,-1.5417758052175927,3.5491802513502524,2.6556741514333573,0.3443061993948582,3.285196134499565,-2.0464349065431278,1.6738619652882785,-0.23818692761586824,0.5847653265563068,0.19322985148629535,0.36520852896444506,1.392310058750564,-0.26419124276665046,0.32323817115644027,0.8394016868466264,0.8394016868466264,3.351325980333631,-0.26419124276665046,1.7791593908234755,2.732890881137026,2.6556741514333573,1.419454626258951,-0.5665281275626076,1.8465093473865353
| 3,193
|
Trans golgi network
| 25
| 67
| 3.136129
| 0.001712
|
P53365,P20645,Q7Z6M1,P61026,Q96A57,Q9HC07,O15127,Q9H4A6,P56377,Q9Y5X1,Q8N2H4,P05067,O15126,P11717,Q7Z3C6,O14828,Q9UID3,Q969E2,O60499,O00443,Q4J6C6,O75592,Q9BTU6,P04062,P53367
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
261,633,394,637,143,146,274,426,545,308,182,438,436,568,471,462,615,228,103,350,235,620,641,122,248
|
350,462,436,274,1705,1492,103,1396,2307,620,122,438,1990,568,633,2956,1847,2815,1897,777,1454,1360,261,248,545,2233,1901,637,1247,833,994,1625,1906,1910,1407,2511,838,2157,235,1211,1514,471,394,817,182,1214,1638,1215,1519,228,143,1347,1824,641,1307,666,426,1183,1974,146,2292,707,615,1603,3137,855,308
|
1.0543605595517835,0.8394016868466264,0.8907287812193003,1.3229726085415559,-0.16155054834083413,-0.03822288271037234,2.2812210779922095,0.009638014956759703,-0.5092252179873332,0.6038310370230041,2.153135324237049,0.8907287812193003,-0.31690808027229783,0.6786968138424812,0.5847653265563068,-1.1364774707508174,-0.23818692761586824,-0.934824649241834,-0.26419124276665046,0.42694183408394704,-0.014190283332690111,0.03326476765043723,1.3786129091151909,1.4059236947909328,0.7153141117668748,-0.4529950413267082,-0.26419124276665046,0.5847653265563068,0.10296255264400622,0.38594722827302785,0.259018664523886,-0.11157482962869282,-0.26419124276665046,-0.26419124276665046,0.009638014956759703,-0.6249367779380635,0.38594722827302785,-0.39780592754705757,1.446271558144171,0.12580968009238108,-0.03822288271037234,0.8394016868466264,0.9739374379111466,0.40652433044515934,1.6858254775131012,0.12580968009238108,-0.11157482962869282,0.12580968009238108,-0.03822288271037234,1.472767115384539,1.9117156067218775,0.0566926794738131,-0.21241421080737602,0.5847653265563068,0.07992440556882748,0.5655565678430635,0.9243562959106226,0.1484683010782358,-0.2904304927178063,1.9009921408923331,-0.4809780479553145,0.5070546681307051,0.6227553904440447,-0.08691226787820137,-1.8273246014917721,0.38594722827302785,1.207423100369303
| 3,193
|
Intrinsic component of mitochondrial inner membrane
| 19
| 30
| 3.131827
| 0.001737
|
O60830,Q99595,O43819,Q6P4A7,Q9NVH1,Q16891,Q9HC21,P17152,Q5XKP0,Q96NB2,Q9Y2R0,Q9H3K2,Q15070,Q13505,Q6UXV4,Q9Y512,Q9BUR5,O14925,Q16134
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,3,514,142,270,660,405,529,549,677,44,302,48,51,449,332,335,211,613
|
211,514,0,1610,1026,529,3155,2614,1111,51,48,613,660,1295,549,142,449,876,677,3,335,302,879,2387,405,270,698,44,1019,332
|
1.5376396248754793,0.7514043268649677,4.042548479567164,-0.11157482962869282,0.23726642403703146,0.7334243460639536,-2.0464349065431278,-0.7146987125093559,0.19322985148629535,2.746560633651398,2.800152733484291,0.6227553904440447,0.5655565678430635,0.07992440556882748,0.7153141117668748,1.9117156067218775,0.8737391734444331,0.36520852896444506,0.5462030417796385,3.6753208773984025,1.1167917984678513,1.2221896821440608,0.36520852896444506,-0.5377405503528547,0.9575234066599015,1.3509647782580774,0.5267030007716262,2.8520707218101506,0.259018664523886,1.1321439407679112
| 3,193
|
Hydrolase activity acting on glycosyl bonds
| 14
| 27
| 3.128762
| 0.001755
|
P54802,P10253,O75503,P06865,P06280,P16278,Q16706,P17900,O60476,P04066,O60502,P04062,Q9BTY2,O43598
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
166,102,104,293,298,11,362,234,398,400,52,122,250,446
|
2086,446,398,52,104,122,400,298,293,726,102,2676,11,234,1320,3119,1240,1358,166,2050,517,1726,362,1114,2756,250,793
|
-0.37059222129993374,0.8737391734444331,0.9575234066599015,2.7397396070190534,2.2812210779922095,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,0.46730587199900714,2.2900460179099036,-0.7760255732552376,3.418959561273887,1.446271558144171,0.0566926794738131,-1.7020688805675812,0.10296255264400622,0.03326476765043723,1.7791593908234755,-0.3436274762646461,0.7514043268649677,-0.16155054834083413,1.0384916258428032,0.19322985148629535,-0.8385853324054076,1.4059236947909328,0.42694183408394704
| 3,193
|
Glycoside hydrolase superfamily [IPR017853]
| 8
| 14
| 3.124484
| 0.001781
|
P10253,P54802,P06865,P06280,P16278,O60502,P04062,Q9BTY2
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
102,166,293,298,11,52,122,250
|
52,122,400,298,293,726,727,102,11,1358,166,1726,250,1307
|
2.7397396070190534,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,0.46730587199900714,0.46730587199900714,2.2900460179099036,3.418959561273887,0.03326476765043723,1.7791593908234755,-0.16155054834083413,1.4059236947909328,0.07992440556882748
| 3,193
|
Steroid binding
| 10
| 19
| 3.110449
| 0.001868
|
P35610,P04062,P21796,Q14849,Q14108,P45880,O15173,O00264,P30536,P38435
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
288,122,7,74,14,15,76,371,58,255
|
371,858,76,2311,122,712,2736,7,1847,2640,58,288,255,15,457,14,74,1429,1738
|
1.006432544850282,0.36520852896444506,2.5057902110255577,-0.5092252179873332,2.153135324237049,0.48725623745593405,-0.8385853324054076,3.5491802513502524,-0.23818692761586824,-0.7452104629394918,2.6556741514333573,1.280324185022697,1.392310058750564,3.285196134499565,0.8566305867164241,3.309160878702859,2.536807538431712,0.009638014956759703,-0.16155054834083413
| 3,193
|
Sphingolipid metabolism
| 8
| 10
| 3.071866
| 0.002127
|
Q06136,P07602,O95470,P17900,Q16880,Q13510,O15269,P04062
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
99,72,171,234,273,116,303,122
|
303,1060,171,122,72,234,99,116,273,347
|
1.207423100369303,0.21533758545793177,1.744645033106282,2.153135324237049,2.5672903217950718,1.446271558144171,2.3075717767503545,2.1998773817605315,1.3370121237135937,1.0857828718447309
| 3,193
|
Liposaccharide metabolic process
| 10
| 15
| 3.059063
| 0.00222
|
P06865,P06280,P16278,P17900,Q9H490,Q16880,P04066,Q99805,Q8NBX0,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
293,298,11,234,368,273,400,367,21,122
|
1166,122,400,298,293,726,11,234,273,21,519,1683,1971,367,368
|
0.1484683010782358,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,0.46730587199900714,3.418959561273887,1.446271558144171,1.3370121237135937,3.148622465340775,0.7514043268649677,-0.13645324700708894,-0.2904304927178063,1.0225160037257737,1.0225160037257737
| 3,193
|
Sterol metabolic process
| 19
| 40
| 3.056048
| 0.002243
|
Q9BQE5,P49748,Q14739,Q14534,Q16850,P35610,Q15800,Q15125,Q8WTV0,P16435,P05067,Q15392,Q14849,O75845,P48449,Q9UBM7,Q9UKR5,P04035,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
6,391,147,403,158,288,35,294,43,299,438,63,74,224,226,370,115,245,122
|
858,224,2311,1787,245,122,438,1709,2401,299,2607,3113,288,581,582,3000,226,391,1455,2746,457,1952,2825,2913,403,147,74,1411,294,2874,63,921,35,158,2328,43,6,370,1695,115
|
0.36520852896444506,1.4858962903240147,-0.5092252179873332,-0.21241421080737602,1.419454626258951,2.153135324237049,0.8907287812193003,-0.16155054834083413,-0.5665281275626076,1.2368621349000533,-0.7146987125093559,-1.661294066844009,1.280324185022697,0.6601866548649779,0.6601866548649779,-1.2422071670625843,1.4858962903240147,0.9739374379111466,-0.014190283332690111,-0.8385853324054076,0.8566305867164241,-0.2904304927178063,-0.934824649241834,-1.0678476456651755,0.9575234066599015,1.8684775279957868,2.536807538431712,0.009638014956759703,1.2514414118114898,-1.00064563472387,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,-0.5092252179873332,2.871125247428219,3.5925647235517952,1.0225160037257737,-0.13645324700708894,2.2182584184461103
| 3,193
|
Golgi apparatus subcompartment
| 37
| 92
| 3.051927
| 0.002274
|
P20645,P53365,Q7Z6M1,P61026,P51572,Q96A57,Q9HC07,O15127,O00461,Q15363,Q9H4A6,P56377,Q96L58,Q9Y5X1,Q8N2H4,Q8WVQ1,P05067,O15126,P11717,Q12893,Q7Z3C6,O14828,Q9UID3,O95249,Q969E2,P04062,O60499,O00443,Q16706,Q10471,Q4J6C6,P04439,O75592,Q10713,Q9BTU6,Q9Y3A3,P53367
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
633,261,394,637,141,143,146,274,28,29,426,545,291,308,182,311,438,436,568,325,471,462,615,348,228,122,103,350,362,489,235,233,620,497,641,252,248
|
350,28,1099,462,436,274,1705,1492,103,1396,2137,2307,620,348,2185,122,233,438,1990,3092,568,633,2956,1847,2815,1897,2503,777,1454,141,1360,261,248,545,2233,1901,637,1247,833,994,1625,1906,2748,489,1910,497,1407,325,2511,838,674,2157,29,362,235,1211,1514,471,394,817,182,1048,1214,1259,311,1638,1215,1519,228,143,291,1347,1824,2599,2381,641,1307,666,426,1183,1974,146,2292,707,615,1603,3137,855,1700,986,252,308
|
1.0543605595517835,3.078186020550252,0.19322985148629535,0.8394016868466264,0.8907287812193003,1.3229726085415559,-0.16155054834083413,-0.03822288271037234,2.2812210779922095,0.009638014956759703,-0.39780592754705757,-0.5092252179873332,0.6038310370230041,1.070123936480939,-0.4252722805882104,2.153135324237049,1.446271558144171,0.8907287812193003,-0.31690808027229783,-1.5417758052175927,0.6786968138424812,0.5847653265563068,-1.1364774707508174,-0.23818692761586824,-0.934824649241834,-0.26419124276665046,-0.6249367779380635,0.42694183408394704,-0.014190283332690111,1.9223825076951602,0.03326476765043723,1.3786129091151909,1.4059236947909328,0.7153141117668748,-0.4529950413267082,-0.26419124276665046,0.5847653265563068,0.10296255264400622,0.38594722827302785,0.259018664523886,-0.11157482962869282,-0.26419124276665046,-0.8385853324054076,0.8045775073895869,-0.26419124276665046,0.7869794546562088,0.009638014956759703,1.1321439407679112,-0.6249367779380635,0.38594722827302785,0.5462030417796385,-0.39780592754705757,3.078186020550252,1.0384916258428032,1.446271558144171,0.12580968009238108,-0.03822288271037234,0.8394016868466264,0.9739374379111466,0.40652433044515934,1.6858254775131012,0.23726642403703146,0.12580968009238108,0.10296255264400622,1.1925614229636166,-0.11157482962869282,0.12580968009238108,-0.03822288271037234,1.472767115384539,1.9117156067218775,1.2659284528512882,0.0566926794738131,-0.21241421080737602,-0.6844855875507391,-0.5377405503528547,0.5847653265563068,0.07992440556882748,0.5655565678430635,0.9243562959106226,0.1484683010782358,-0.2904304927178063,1.9009921408923331,-0.4809780479553145,0.5070546681307051,0.6227553904440447,-0.08691226787820137,-1.8273246014917721,0.38594722827302785,-0.13645324700708894,0.28059656391052684,1.4059236947909328,1.207423100369303
| 3,193
|
Molecular transducer activity
| 7
| 31
| 3.050445
| 0.002285
|
Q15629,Q9BUN8,P30536,Q8WTV0,Q14108,O15173,Q99720
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,165,58,43,14,76,26
|
1236,858,76,2351,1890,568,633,58,1898,1068,1401,1905,835,690,950,14,839,64,899,186,422,1763,43,930,1736,359,26,165,2174,2128,853
|
0.10296255264400622,0.36520852896444506,2.5057902110255577,-0.5377405503528547,-0.26419124276665046,0.6786968138424812,0.5847653265563068,2.6556741514333573,-0.26419124276665046,0.21533758545793177,0.009638014956759703,-0.26419124276665046,0.38594722827302785,0.5267030007716262,0.30200233977580343,3.309160878702859,0.38594722827302785,2.62670988147732,0.3443061993948582,1.6738619652882785,0.9243562959106226,-0.18686982059176915,2.871125247428219,0.32323817115644027,-0.16155054834083413,1.0543605595517835,3.0892345539041384,1.7905380137060627,-0.39780592754705757,-0.37059222129993374,0.38594722827302785
| 3,193
|
Golgi membrane
| 68
| 135
| 3.047661
| 0.002306
|
P24390,Q7LGA3,Q8IV08,P61026,O15260,Q9Y3E0,Q9BXS5,P51572,Q14108,O60476,O95721,Q9HC07,O43505,P61923,P61019,P62820,O00461,Q15363,Q9Y3B3,P42345,Q15382,Q9H7Z7,P56377,Q96L58,O43731,Q9H4A6,P49755,Q6ZRP7,Q14789,Q8IZA0,Q08AM6,Q8N2H4,Q9BVK6,O95295,Q9Y678,P35613,P11717,Q15392,Q8NF37,Q12893,P10321,P52292,Q9BUR5,Q96S66,Q8NCH0,Q7Z3C6,Q9Y282,Q9UM00,O95197,O95249,O15498,Q13190,Q9P2W9,Q8TB61,O15258,O60499,Q12907,Q16706,Q10471,Q86Y82,P04439,Q99640,Q8N6H7,Q92896,Q10713,Q9Y371,P53367,Q9NTJ5
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,131,262,637,259,396,666,141,14,398,399,146,275,657,656,531,28,29,30,409,548,427,545,291,36,426,417,295,674,173,690,182,444,686,710,317,568,63,318,325,455,333,335,474,82,471,85,214,86,348,604,354,100,101,351,103,490,362,489,627,233,365,500,243,497,512,248,645
|
912,28,2635,1274,798,1394,351,259,604,275,1837,36,1705,398,103,2137,1574,86,348,686,399,1497,233,2352,3092,455,863,568,1847,2,990,317,2406,1897,409,1069,1241,867,2360,417,777,141,3156,333,248,2504,2267,545,2233,2147,1622,1901,656,637,1247,657,1903,531,833,994,2748,690,489,1910,497,325,490,354,760,14,674,2776,2157,29,548,63,998,362,2417,1143,295,131,471,1962,627,926,262,173,182,500,1679,82,318,101,1048,786,1214,1259,1215,1519,243,291,1347,474,365,335,444,3089,666,961,3062,426,427,1008,1183,146,1057,645,707,2256,100,1933,1602,1696,2923,3137,214,85,986,2992,3104,512,30,396,710
|
0.32323817115644027,3.078186020550252,-0.7452104629394918,0.07992440556882748,0.40652433044515934,0.009638014956759703,1.0543605595517835,1.3786129091151909,0.6227553904440447,1.3229726085415559,-0.23818692761586824,2.96913415144942,-0.16155054834083413,0.9575234066599015,2.2812210779922095,-0.39780592754705757,-0.08691226787820137,2.4176108705977826,1.070123936480939,0.5267030007716262,0.9575234066599015,-0.03822288271037234,1.446271558144171,-0.5377405503528547,-1.5417758052175927,0.8566305867164241,0.36520852896444506,0.6786968138424812,-0.23818692761586824,3.7462657069794476,0.259018664523886,1.162548846164761,-0.5665281275626076,-0.26419124276665046,0.9409967716069575,0.21533758545793177,0.10296255264400622,0.36520852896444506,-0.5377405503528547,0.9243562959106226,0.42694183408394704,1.9223825076951602,-2.0464349065431278,1.1167917984678513,1.4059236947909328,-0.6249367779380635,-0.4809780479553145,0.7153141117668748,-0.4529950413267082,-0.39780592754705757,-0.11157482962869282,-0.26419124276665046,0.5655565678430635,0.5847653265563068,0.10296255264400622,0.5655565678430635,-0.26419124276665046,0.7334243460639536,0.38594722827302785,0.259018664523886,-0.8385853324054076,0.5267030007716262,0.8045775073895869,-0.26419124276665046,0.7869794546562088,1.1321439407679112,0.8045775073895869,1.0543605595517835,0.44720170401297976,3.309160878702859,0.5462030417796385,-0.8703399800828923,-0.39780592754705757,3.078186020550252,0.7153141117668748,2.6339966056994,0.259018664523886,1.0384916258428032,-0.5665281275626076,0.17094088359372295,1.2514414118114898,1.985222235335816,0.8394016868466264,-0.2904304927178063,0.6038310370230041,0.32323817115644027,1.3786129091151909,1.7330122185385242,1.6858254775131012,0.7869794546562088,-0.13645324700708894,2.4420909128633217,1.162548846164761,2.2988294808347165,0.23726642403703146,0.42694183408394704,0.12580968009238108,0.10296255264400622,0.12580968009238108,-0.03822288271037234,1.4329036514563958,1.2659284528512882,0.0566926794738131,0.8394016868466264,1.0384916258428032,1.1167917984678513,0.8907287812193003,-1.5028434769808663,0.5655565678430635,0.30200233977580343,-1.3886547156284181,0.9243562959106226,0.9243562959106226,0.259018664523886,0.1484683010782358,1.9009921408923331,0.23726642403703146,0.5847653265563068,0.5070546681307051,-0.4529950413267082,2.3075717767503545,-0.26419124276665046,-0.08691226787820137,-0.13645324700708894,-1.0678476456651755,-1.8273246014917721,1.5376396248754793,2.4339675988258307,0.28059656391052684,-1.2065841027857491,-1.581156126510372,0.7692555416447295,3.067058131253242,0.9739374379111466,0.5070546681307051
| 3,193
|
Tetrapyrrole binding
| 10
| 16
| 3.031005
| 0.002437
|
P30519,O43169,O15173,P09601,O00264,Q8WUJ1,Q7KZN9,Q6UW02,Q16850,Q9H7Z7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
69,46,76,17,371,179,150,189,158,427
|
371,76,46,752,17,1357,69,456,158,189,150,179,1217,679,427,2920
|
1.006432544850282,2.5057902110255577,2.832792341598909,0.44720170401297976,3.250973747172662,0.03326476765043723,2.589810382359061,0.8566305867164241,1.8243030426289284,1.661830514045592,1.8465093473865353,1.6977216604154457,0.12580968009238108,0.5462030417796385,0.9243562959106226,-1.0678476456651755
| 3,193
|
Endoplasmic reticulum to golgi vesicle mediated transport
| 24
| 66
| 3.024128
| 0.002494
|
P24390,Q9NR31,P51572,P61019,P62820,Q15363,Q9Y3B3,O43731,P49755,Q15437,Q9BVK6,P55735,Q9Y678,Q9Y6Y8,Q8NHH9,Q9Y282,Q9HCU5,O95249,O15498,Q13190,Q9P2W9,Q12907,Q9Y3A6,Q96PC5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,523,141,656,531,29,30,36,417,693,444,440,710,476,472,85,744,348,604,354,100,490,513,386
|
1532,2635,798,1394,604,2304,1837,36,2137,1355,1574,2447,348,2496,1194,942,1169,2,990,1069,867,417,141,1360,2504,2267,2321,2969,440,656,531,490,354,1723,29,998,693,1172,737,1633,1116,472,1259,1215,1681,386,444,961,1384,744,1057,904,523,2256,100,1933,2978,1979,85,986,795,513,30,1879,710,476
|
-0.062462590653624604,-0.7452104629394918,0.40652433044515934,0.009638014956759703,0.6227553904440447,-0.5092252179873332,-0.23818692761586824,2.96913415144942,-0.39780592754705757,0.03326476765043723,-0.08691226787820137,-0.5955921179420027,1.070123936480939,-0.6249367779380635,0.12580968009238108,0.30200233977580343,0.1484683010782358,3.7462657069794476,0.259018664523886,0.21533758545793177,0.36520852896444506,0.9243562959106226,1.9223825076951602,0.03326476765043723,-0.6249367779380635,-0.4809780479553145,-0.5092252179873332,-1.1713430341599453,0.8907287812193003,0.5655565678430635,0.7334243460639536,0.8045775073895869,1.0543605595517835,-0.16155054834083413,3.078186020550252,0.259018664523886,0.5267030007716262,0.1484683010782358,0.46730587199900714,-0.11157482962869282,0.19322985148629535,0.8394016868466264,0.10296255264400622,0.12580968009238108,-0.13645324700708894,0.9902400838282385,0.8907287812193003,0.30200233977580343,0.03326476765043723,0.46730587199900714,0.23726642403703146,0.3443061993948582,0.7514043268649677,-0.4529950413267082,2.3075717767503545,-0.26419124276665046,-1.1713430341599453,-0.2904304927178063,2.4339675988258307,0.28059656391052684,0.42694183408394704,0.7692555416447295,3.067058131253242,-0.23818692761586824,0.5070546681307051,0.8394016868466264
| 3,193
|
Cholesterol metabolism with bloch and kandutschrussell pathways
| 12
| 25
| 2.992885
| 0.002764
|
P35610,O75845,P48449,Q15800,Q15125,O00767,Q9UBM7,Q14739,O95864,P04035,Q15392,Q16850
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
288,224,226,35,294,360,370,147,374,245,63,158
|
360,1985,224,1750,374,245,2401,1579,288,581,226,1401,2746,2825,2913,403,147,294,2874,63,921,35,158,1828,370
|
1.0384916258428032,-0.31690808027229783,1.4858962903240147,-0.18686982059176915,1.006432544850282,1.419454626258951,-0.5665281275626076,-0.08691226787820137,1.280324185022697,0.6601866548649779,1.4858962903240147,0.009638014956759703,-0.8385853324054076,-0.934824649241834,-1.0678476456651755,0.9575234066599015,1.8684775279957868,1.2514414118114898,-1.00064563472387,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,-0.21241421080737602,1.0225160037257737
| 3,193
|
Aminoglycan metabolic process
| 9
| 12
| 2.990011
| 0.00279
|
Q96L58,Q7LGA3,P54802,P06865,P16278,P04066,Q8NCH0,O43505,P15586
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
291,131,166,293,11,400,82,275,310
|
275,485,400,293,726,310,11,166,1625,131,82,291
|
1.3229726085415559,0.8045775073895869,0.9575234066599015,1.2514414118114898,0.46730587199900714,1.1925614229636166,3.418959561273887,1.7791593908234755,-0.11157482962869282,1.985222235335816,2.4420909128633217,1.2659284528512882
| 3,193
|
Nuclear outer membrane endoplasmic reticulum membrane network
| 130
| 285
| 2.980923
| 0.002874
|
P24390,Q9P035,Q9BQE5,Q92643,P43307,Q13724,Q14108,P09601,Q15005,P61619,O75915,Q99720,Q8N0U8,Q15363,Q9Y3B3,Q15382,Q5BJF2,Q15800,O43731,Q8N511,O43865,Q9H2M9,Q15392,Q15629,P30519,Q14849,O75844,Q9Y282,Q9HD20,O95197,Q86UE4,Q06136,Q9P2W9,Q8TB61,Q9NQC3,Q86XL3,Q03518,Q9UKR5,P51648,O60725,P51572,Q14739,Q96KC8,Q9UBV2,Q9BRR6,Q16850,Q96G23,Q9BUN8,O95470,P67812,Q86YN1,Q5VUD6,Q9Y5M8,Q9BV10,Q8N2K0,P46977,Q9UM00,Q96GC9,P07099,O75845,P48449,Q8TCT9,Q07065,Q15904,Q53GQ0,P04439,P04035,Q9Y4P3,P38435,Q8IV08,O15260,P50402,Q12959,Q96RL7,Q9NZ08,Q96A33,Q70UQ0,P57088,P35610,Q15125,P16615,P16435,Q6NUM9,O15269,Q8WVQ1,Q9BT22,P35613,Q8NF37,Q2TAA5,Q9UBU6,Q6NUQ4,Q9NPA0,P52292,Q9BUR5,Q92604,Q9NZ01,Q99442,Q13190,O00767,Q99640,Q9H490,Q9UBM7,O00264,O43852,O95864,Q6UWP7,Q96PC5,Q9Y5L0,Q14534,A1L0T0,P42345,Q9H3N1,P49755,Q12981,O95674,Q9BVK6,Q99735,P55735,P06493,P10321,O76024,Q96S66,Q8NHH9,Q7Z3C6,P62942,Q12907,Q86UL3,Q10471,Q9Y3A6,Q8N5M9
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,524,6,519,10,517,14,17,533,530,528,26,27,29,30,548,32,35,36,49,553,577,63,64,69,74,81,85,87,86,92,99,100,101,113,112,111,115,130,140,141,147,148,154,153,158,159,165,171,172,177,178,183,199,203,206,214,220,222,224,226,227,229,230,236,233,245,253,255,262,259,266,279,285,287,284,283,282,288,294,300,299,301,303,311,316,317,318,326,331,334,336,333,335,343,347,359,354,360,365,368,370,371,372,374,385,386,397,403,407,409,425,417,420,415,444,442,440,439,455,454,474,472,471,481,490,492,489,513,511
|
617,407,1352,371,1098,2605,360,2635,798,771,1572,2261,1394,259,303,1060,2304,800,36,372,553,1985,1396,140,1166,1355,1574,81,224,528,454,1317,2734,2311,1888,2447,86,2496,171,1194,942,1750,415,374,2036,1787,1497,245,233,687,1030,439,3105,222,2314,2352,17,455,2452,299,300,1066,1447,1847,2931,2,1946,3087,865,2843,2718,69,3043,2144,1579,990,288,317,581,255,1896,409,1451,10,206,1069,226,1285,1241,867,1582,417,1757,266,756,141,130,1360,333,2504,2267,2321,2969,440,282,3059,2147,1622,1544,656,637,1247,1545,530,713,657,2823,810,2150,481,2461,172,2238,1667,111,1954,99,229,489,1365,490,279,420,354,1668,2273,517,14,872,2365,838,403,147,74,533,1549,814,2240,294,29,548,63,998,693,64,921,35,230,2417,158,326,236,32,661,1172,178,1336,301,737,334,954,385,283,875,471,92,492,1338,112,177,262,2831,1732,27,203,49,2373,511,1554,318,1003,472,1175,2067,101,1341,587,2594,227,1118,929,1865,1259,311,877,1818,343,519,2332,1683,1342,284,1640,1050,159,220,1969,575,148,386,285,1971,474,359,365,26,442,6,153,2025,2120,316,631,165,335,199,1054,3142,444,1429,1738,1973,961,577,425,368,1008,1092,744,87,880,336,113,645,682,707,347,287,524,909,2256,2128,100,1933,1602,370,331,154,853,115,3137,214,2490,85,938,884,513,30,2963,253,397,183,3160,710,1833
|
0.6038310370230041,0.9409967716069575,0.03326476765043723,1.006432544850282,0.19322985148629535,-0.7146987125093559,1.0384916258428032,-0.7452104629394918,0.40652433044515934,0.42694183408394704,-0.08691226787820137,-0.4809780479553145,0.009638014956759703,1.3786129091151909,1.207423100369303,0.21533758545793177,-0.5092252179873332,0.40652433044515934,2.96913415144942,1.006432544850282,0.6970721128067479,-0.31690808027229783,0.009638014956759703,1.9223825076951602,0.1484683010782358,0.03326476765043723,-0.08691226787820137,2.4501778760429596,1.4858962903240147,0.7334243460639536,0.8566305867164241,0.0566926794738131,-0.8385853324054076,-0.5092252179873332,-0.26419124276665046,-0.5955921179420027,2.4176108705977826,-0.6249367779380635,1.744645033106282,0.12580968009238108,0.30200233977580343,-0.18686982059176915,0.9243562959106226,1.006432544850282,-0.3436274762646461,-0.21241421080737602,-0.03822288271037234,1.419454626258951,1.446271558144171,0.5267030007716262,0.23726642403703146,0.8907287812193003,-1.6209927176562446,1.4989473958627886,-0.5092252179873332,-0.5377405503528547,3.250973747172662,0.8566305867164241,-0.5955921179420027,1.2368621349000533,1.2368621349000533,0.21533758545793177,-0.014190283332690111,-0.23818692761586824,-1.101981072569348,3.7462657069794476,-0.2904304927178063,-1.5028434769808663,0.36520852896444506,-0.9675653554604676,-0.8071488815311059,2.589810382359061,-1.3514355919674153,-0.39780592754705757,-0.08691226787820137,0.259018664523886,1.280324185022697,1.162548846164761,0.6601866548649779,1.392310058750564,-0.26419124276665046,0.9409967716069575,-0.014190283332690111,3.4750650461264545,1.5503857345605445,0.21533758545793177,1.4858962903240147,0.07992440556882748,0.10296255264400622,0.36520852896444506,-0.08691226787820137,0.9243562959106226,-0.18686982059176915,1.3648314259575298,0.44720170401297976,1.9223825076951602,2.015915696016737,0.03326476765043723,1.1167917984678513,-0.6249367779380635,-0.4809780479553145,-0.5092252179873332,-1.1713430341599453,0.8907287812193003,1.2946295225860096,-1.3886547156284181,-0.39780592754705757,-0.11157482962869282,-0.062462590653624604,0.5655565678430635,0.5847653265563068,0.10296255264400622,-0.062462590653624604,0.7334243460639536,0.48725623745593405,0.5655565678430635,-0.934824649241834,0.40652433044515934,-0.39780592754705757,0.8220511190203319,-0.5955921179420027,1.7330122185385242,-0.4529950413267082,-0.13645324700708894,2.2364631467360248,-0.2904304927178063,2.3075717767503545,1.4595591237186676,0.8045775073895869,0.03326476765043723,0.8045775073895869,1.3088453672804772,0.9243562959106226,1.0543605595517835,-0.13645324700708894,-0.4809780479553145,0.7514043268649677,3.309160878702859,0.36520852896444506,-0.5377405503528547,0.38594722827302785,0.9575234066599015,1.8684775279957868,2.536807538431712,0.7334243460639536,-0.062462590653624604,0.40652433044515934,-0.4529950413267082,1.2514414118114898,3.078186020550252,0.7153141117668748,2.6339966056994,0.259018664523886,0.5267030007716262,2.62670988147732,0.32323817115644027,2.975065555239934,1.4595591237186676,-0.5665281275626076,1.8243030426289284,1.1321439407679112,1.446271558144171,3.0502155042807657,0.5655565678430635,0.1484683010782358,1.6977216604154457,0.0566926794738131,1.2221896821440608,0.46730587199900714,1.1167917984678513,0.30200233977580343,0.9902400838282385,1.2946295225860096,0.36520852896444506,0.8394016868466264,2.359178009634381,0.8045775073895869,0.0566926794738131,2.2364631467360248,1.7095511162040427,1.3786129091151909,-0.934824649241834,-0.16155054834083413,3.083720150229578,1.575655220295083,2.7869149799952893,-0.5377405503528547,0.7692555416447295,-0.062462590653624604,1.162548846164761,0.259018664523886,0.8394016868466264,0.1484683010782358,-0.3436274762646461,2.2988294808347165,0.0566926794738131,0.6601866548649779,-0.6844855875507391,1.472767115384539,0.19322985148629535,0.32323817115644027,-0.23818692761586824,0.10296255264400622,1.1925614229636166,0.36520852896444506,-0.21241421080737602,1.1013384647454063,0.7514043268649677,-0.5092252179873332,-0.13645324700708894,0.0566926794738131,1.2946295225860096,-0.11157482962869282,0.23726642403703146,1.8243030426289284,1.5248183397306079,-0.2904304927178063,0.6786968138424812,1.8575229481079278,0.9902400838282385,1.2946295225860096,-0.2904304927178063,0.8394016868466264,1.0543605595517835,1.0384916258428032,3.0892345539041384,0.8907287812193003,3.5925647235517952,1.8354362171377097,-0.31690808027229783,-0.37059222129993374,1.1776036696350574,0.6038310370230041,1.7905380137060627,1.1167917984678513,1.6130128562407051,0.23726642403703146,-1.8700849622133329,0.8907287812193003,0.009638014956759703,-0.16155054834083413,-0.2904304927178063,0.30200233977580343,0.6786968138424812,0.9243562959106226,1.0225160037257737,0.259018664523886,0.21533758545793177,0.46730587199900714,2.4176108705977826,0.36520852896444506,1.1167917984678513,2.2364631467360248,0.5847653265563068,0.5462030417796385,0.5070546681307051,1.0857828718447309,1.2946295225860096,0.7514043268649677,0.3443061993948582,-0.4529950413267082,-0.37059222129993374,2.3075717767503545,-0.26419124276665046,-0.08691226787820137,1.0225160037257737,1.1321439407679112,1.8354362171377097,0.38594722827302785,2.2182584184461103,-1.8273246014917721,1.5376396248754793,-0.5955921179420027,2.4339675988258307,0.32323817115644027,0.36520852896444506,0.7692555416447295,3.067058131253242,-1.1364774707508174,1.4059236947909328,0.9739374379111466,1.6858254775131012,-2.1379443966160254,0.5070546681307051,-0.21241421080737602
| 3,193
|
Endoplasmic reticulum organization
| 20
| 40
| 2.977756
| 0.002904
|
P61026,Q5J8M3,P61619,Q00765,Q96A33,Q15363,P57088,Q12981,Q9H2M9,P46379,Q15629,Q9NPA0,Q8NHH9,O95197,Q9P2W9,Q12907,Q9NQC3,O43681,A0FGR8,Q8N5M9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
637,661,530,546,284,29,282,420,577,62,64,336,472,86,100,490,113,619,617,511
|
617,2949,1098,1440,1394,619,1747,2447,86,2496,62,867,282,637,530,546,490,420,1549,814,29,64,661,1172,2280,511,1554,1003,472,284,2120,577,1384,880,336,113,707,909,2256,100
|
0.6038310370230041,-1.1364774707508174,0.19322985148629535,-0.014190283332690111,0.009638014956759703,0.6038310370230041,-0.18686982059176915,-0.5955921179420027,2.4176108705977826,-0.6249367779380635,2.6339966056994,0.36520852896444506,1.2946295225860096,0.5847653265563068,0.7334243460639536,0.7153141117668748,0.8045775073895869,0.9243562959106226,-0.062462590653624604,0.40652433044515934,3.078186020550252,2.62670988147732,0.5655565678430635,0.1484683010782358,-0.4809780479553145,0.7692555416447295,-0.062462590653624604,0.259018664523886,0.8394016868466264,1.2946295225860096,-0.37059222129993374,0.6786968138424812,0.03326476765043723,0.36520852896444506,1.1167917984678513,2.2364631467360248,0.5070546681307051,0.3443061993948582,-0.4529950413267082,2.3075717767503545
| 3,193
|
Steroid metabolic process
| 25
| 67
| 2.976777
| 0.002913
|
Q9BQE5,P49748,Q14739,Q14534,Q16850,P35610,Q15800,Q15125,Q8WTV0,P16435,O95470,P30536,P05067,Q15392,Q14849,Q99538,O75845,P48449,Q53GQ0,Q9UBM7,Q9UKR5,Q13510,P04035,P04062,P38435
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
6,391,147,403,158,288,35,294,43,299,171,58,438,63,74,346,224,226,236,370,115,116,245,122,255
|
966,858,224,2311,171,1787,245,122,712,438,3184,1709,2401,2842,299,1847,2640,2607,3112,515,58,3113,288,581,255,582,3000,226,391,2744,1324,1455,2746,457,1952,2825,2463,116,2913,403,147,74,1411,294,2874,63,1671,1463,921,35,158,236,2328,784,550,43,2975,346,3008,6,1738,3062,370,1695,1437,115,2762
|
0.28059656391052684,0.36520852896444506,1.4858962903240147,-0.5092252179873332,1.744645033106282,-0.21241421080737602,1.419454626258951,2.153135324237049,0.48725623745593405,0.8907287812193003,-3.200072430029395,-0.16155054834083413,-0.5665281275626076,-0.9675653554604676,1.2368621349000533,-0.23818692761586824,-0.7452104629394918,-0.7146987125093559,-1.661294066844009,0.7514043268649677,2.6556741514333573,-1.661294066844009,1.280324185022697,0.6601866548649779,1.392310058750564,0.6601866548649779,-1.2422071670625843,1.4858962903240147,0.9739374379111466,-0.8385853324054076,0.0566926794738131,-0.014190283332690111,-0.8385853324054076,0.8566305867164241,-0.2904304927178063,-0.934824649241834,-0.5955921179420027,2.1998773817605315,-1.0678476456651755,0.9575234066599015,1.8684775279957868,2.536807538431712,0.009638014956759703,1.2514414118114898,-1.00064563472387,2.6339966056994,-0.13645324700708894,-0.014190283332690111,0.32323817115644027,2.975065555239934,1.8243030426289284,1.446271558144171,-0.5092252179873332,0.42694183408394704,0.7153141117668748,2.871125247428219,-1.1713430341599453,1.0857828718447309,-1.2422071670625843,3.5925647235517952,-0.16155054834083413,-1.3886547156284181,1.0225160037257737,-0.13645324700708894,0.009638014956759703,2.2182584184461103,-0.8385853324054076
| 3,193
|
membrane trafficking regulatory protein
| 6
| 18
| 2.945069
| 0.003229
|
P24390,O43731,Q8WTV0,P13473,Q14108,O43760
|
Functions
|
Panther Protein class
|
panther_protein_class
|
2,36,43,204,14,125
|
2604,1314,36,125,2496,309,204,2,14,2156,2157,43,1259,819,1149,1221,2256,720
|
-0.7146987125093559,0.0566926794738131,2.96913415144942,2.09550477869399,-0.6249367779380635,1.1925614229636166,1.5630573692038123,3.7462657069794476,3.309160878702859,-0.39780592754705757,-0.39780592754705757,2.871125247428219,0.10296255264400622,0.40652433044515934,0.17094088359372295,0.12580968009238108,-0.4529950413267082,0.48725623745593405
| 3,193
|
Intra golgi and retrograde golgi to er traffic
| 51
| 99
| 2.94435
| 0.003236
|
P24390,P20645,P53365,Q7Z6M1,O15260,Q14203,P04350,O60476,O95721,Q9BVA1,P61923,P62820,O00461,Q15363,Q9Y3B3,Q12756,Q8IWJ2,O43731,P49755,Q12981,Q13409,Q15042,Q13561,O14653,Q13509,Q9H2M9,Q8N2H4,Q9BVK6,Q9Y678,P11717,Q9Y496,P68371,P84085,P83436,P43034,P52732,Q9UID3,Q6NUQ1,O95249,Q13885,O15498,Q13190,Q9P2W9,O60499,Q9UJW0,Q16706,Q10471,Q8N6H7,O75935,Q5VZE5,Q9BUF5
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
2,633,261,394,259,639,390,398,399,404,657,531,28,29,30,778,817,36,417,420,812,814,813,798,691,577,182,444,710,568,857,320,458,833,583,596,615,737,348,612,604,354,100,103,231,362,489,500,240,242,378
|
1352,1233,28,2635,798,259,604,1101,2304,36,398,103,1131,1574,240,2312,1535,348,399,390,568,1169,633,2,972,990,1897,583,2503,2865,1754,1069,417,596,2266,261,2504,2267,2547,831,657,531,1624,320,2824,833,458,2152,1511,489,778,420,354,812,691,813,612,639,1913,2325,814,3004,29,362,242,737,394,817,182,500,1679,1048,1118,1214,1215,2759,1347,1927,2780,2168,378,404,444,2170,1007,1928,961,577,1183,880,2295,100,1933,615,231,30,857,710,1162
|
0.03326476765043723,0.10296255264400622,3.078186020550252,-0.7452104629394918,0.40652433044515934,1.3786129091151909,0.6227553904440447,0.19322985148629535,-0.5092252179873332,2.96913415144942,0.9575234066599015,2.2812210779922095,0.17094088359372295,-0.08691226787820137,1.4329036514563958,-0.5092252179873332,-0.062462590653624604,1.070123936480939,0.9575234066599015,0.9739374379111466,0.6786968138424812,0.1484683010782358,0.5847653265563068,3.7462657069794476,0.28059656391052684,0.259018664523886,-0.26419124276665046,0.6601866548649779,-0.6249367779380635,-1.00064563472387,-0.18686982059176915,0.21533758545793177,0.9243562959106226,0.6415400506909451,-0.4809780479553145,1.3786129091151909,-0.6249367779380635,-0.4809780479553145,-0.6545664545020534,0.38594722827302785,0.5655565678430635,0.7334243460639536,-0.11157482962869282,1.1473959441543768,-0.934824649241834,0.38594722827302785,0.8566305867164241,-0.39780592754705757,-0.03822288271037234,0.8045775073895869,0.42694183408394704,0.9243562959106226,1.0543605595517835,0.40652433044515934,0.5267030007716262,0.40652433044515934,0.6227553904440447,0.5847653265563068,-0.26419124276665046,-0.5092252179873332,0.40652433044515934,-1.2422071670625843,3.078186020550252,1.0384916258428032,1.4329036514563958,0.46730587199900714,0.9739374379111466,0.40652433044515934,1.6858254775131012,0.7869794546562088,-0.13645324700708894,0.23726642403703146,0.19322985148629535,0.12580968009238108,0.12580968009238108,-0.8385853324054076,0.0566926794738131,-0.26419124276665046,-0.8703399800828923,-0.39780592754705757,1.006432544850282,0.9575234066599015,0.8907287812193003,-0.39780592754705757,0.259018664523886,-0.26419124276665046,0.30200233977580343,0.6786968138424812,0.1484683010782358,0.36520852896444506,-0.4809780479553145,2.3075717767503545,-0.26419124276665046,0.6227553904440447,1.4595591237186676,3.067058131253242,0.38594722827302785,0.5070546681307051,0.17094088359372295
| 3,193
|
Protein localization
| 34
| 73
| 2.94192
| 0.003262
|
O60830,P51648,Q99595,P21796,P50402,P28288,Q9NS69,P09601,O75874,Q15388,O75746,Q15067,Q9UJS0,Q8N4H5,O43615,Q13011,Q13505,Q3ZCQ8,A8MXV4,P05067,Q9NR77,P46379,Q9BY49,O75381,Q9Y512,O15228,P12235,O14925,P12236,Q13190,Q8NBU5,Q5JRX3,Q10713,O43808
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,130,3,7,266,515,16,17,277,280,527,421,428,41,414,431,51,557,429,438,61,62,322,193,332,578,338,211,217,354,628,625,497,505
|
429,1022,966,211,578,414,619,1747,505,0,193,3066,1610,2788,2927,527,277,1316,651,438,1134,752,3184,17,3129,338,217,1654,7,2640,1997,515,3113,3125,3155,973,62,266,1507,130,1324,2409,3059,2102,497,431,354,51,421,280,557,625,2280,41,2832,628,1967,3,3009,322,2253,61,16,698,2256,1697,428,2979,1230,2298,332,1703,1272
|
0.9076007240012801,0.23726642403703146,0.28059656391052684,1.5376396248754793,0.6601866548649779,0.9243562959106226,0.6038310370230041,-0.18686982059176915,0.7692555416447295,4.042548479567164,1.6375613175769943,-1.426290709801661,-0.11157482962869282,-0.902417991440706,-1.101981072569348,0.7334243460639536,1.3088453672804772,0.0566926794738131,0.5655565678430635,0.8907287812193003,0.17094088359372295,0.44720170401297976,-3.200072430029395,3.250973747172662,-1.7850748625508288,1.1013384647454063,1.5248183397306079,-0.13645324700708894,3.5491802513502524,-0.7452104629394918,-0.31690808027229783,0.7514043268649677,-1.661294066844009,-1.743326090815665,-2.0464349065431278,0.28059656391052684,2.6339966056994,1.3648314259575298,-0.03822288271037234,2.015915696016737,0.0566926794738131,-0.5665281275626076,-1.3886547156284181,-0.37059222129993374,0.7869794546562088,0.9076007240012801,1.0543605595517835,2.746560633651398,0.9243562959106226,1.3088453672804772,0.6970721128067479,0.6038310370230041,-0.4809780479553145,2.8899600348937455,-0.934824649241834,0.6038310370230041,-0.2904304927178063,3.6753208773984025,-1.2422071670625843,1.1473959441543768,-0.4529950413267082,2.6412527563805264,3.2657379732892013,0.5267030007716262,-0.4529950413267082,-0.13645324700708894,0.9243562959106226,-1.1713430341599453,0.12580968009238108,-0.4809780479553145,1.1321439407679112,-0.13645324700708894,0.10296255264400622
| 3,193
|
Increased bone mineral density
| 10
| 24
| 2.938159
| 0.003302
|
Q15043,P54802,Q15125,Q13126,Q14108,Q14739,Q9Y4P3,P04062,P51798,Q15392
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
256,166,294,73,14,147,253,122,184,63
|
1708,122,569,916,2956,2681,2818,1285,184,166,2969,2506,2100,73,14,147,256,1810,294,63,1858,319,2339,253
|
-0.16155054834083413,2.153135324237049,0.6786968138424812,0.32323817115644027,-1.1364774707508174,-0.7760255732552376,-0.934824649241834,0.07992440556882748,1.6738619652882785,1.7791593908234755,-1.1713430341599453,-0.6249367779380635,-0.37059222129993374,2.5597189348802236,3.309160878702859,1.8684775279957868,1.392310058750564,-0.21241421080737602,1.2514414118114898,2.6339966056994,-0.23818692761586824,1.162548846164761,-0.5092252179873332,1.4059236947909328
| 3,193
|
Carbohydrate derivative transport
| 10
| 16
| 2.935406
| 0.003331
|
Q99808,Q8TB61,P07602,P05141,P61916,Q8WTV0,P12235,Q9HC21,P12236,Q9NZJ7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
321,101,72,361,457,43,338,405,217,191
|
912,505,361,72,338,217,654,457,835,1112,101,929,43,321,405,191
|
0.32323817115644027,0.7692555416447295,1.0384916258428032,2.5672903217950718,1.1013384647454063,1.5248183397306079,0.5655565678430635,0.8566305867164241,0.38594722827302785,0.19322985148629535,2.2988294808347165,0.32323817115644027,2.871125247428219,1.1473959441543768,0.9575234066599015,1.6497305064842487
| 3,193
|
Steroid biosynthesis
| 10
| 12
| 2.916159
| 0.003544
|
O75845,P48449,P35610,Q15800,Q15125,P38571,Q9UBM7,Q14534,Q15392,Q16850
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
224,226,288,35,294,582,370,403,63,158
|
224,288,581,582,226,403,294,63,921,35,158,370
|
1.4858962903240147,1.280324185022697,0.6601866548649779,0.6601866548649779,1.4858962903240147,0.9575234066599015,1.2514414118114898,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,1.0225160037257737
| 3,193
|
Cytochrome complex assembly
| 9
| 13
| 2.909958
| 0.003615
|
P47985,Q69YU5,P53701,Q6DKK2,O43819,Q9Y2R0,Q15070,Q7KZN9,Q9BSK2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
448,8,456,363,514,44,48,150,212
|
514,1026,448,456,48,8,363,150,630,1427,212,1230,44
|
0.7514043268649677,0.23726642403703146,0.8737391734444331,0.8566305867164241,2.800152733484291,3.5371028334084,1.0384916258428032,1.8465093473865353,0.6038310370230041,0.009638014956759703,1.5376396248754793,0.12580968009238108,2.8520707218101506
| 3,193
|
Metal ion transmembrane transporter activity
| 15
| 24
| 2.904713
| 0.003676
|
Q15043,Q9H2J7,P55011,P61619,Q8TAD4,P16615,P20020,Q9BXP2,P05023,Q9HC07,Q9UM00,Q9HD20,Q9Y6M7,O95202,Q6P4Q7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
256,289,636,530,105,300,580,475,712,146,214,87,151,155,375
|
155,712,2449,1988,2736,727,300,580,636,530,994,1717,256,375,876,105,1736,475,1973,289,146,87,214,151
|
1.8243030426289284,0.48725623745593405,-0.5955921179420027,-0.31690808027229783,-0.8385853324054076,0.46730587199900714,1.2368621349000533,0.6601866548649779,0.5847653265563068,0.7334243460639536,0.259018664523886,-0.16155054834083413,1.392310058750564,1.006432544850282,0.36520852896444506,2.2812210779922095,-0.16155054834083413,0.8394016868466264,-0.2904304927178063,1.280324185022697,1.9009921408923331,2.4176108705977826,1.5376396248754793,1.8465093473865353
| 3,193
|
Proton transmembrane transporter activity
| 15
| 34
| 2.896546
| 0.003773
|
P47985,Q13423,P56385,Q93050,Q9Y487,P05141,P13073,Q96ES6,P12235,P24539,Q7KZN9,Q9UDW1,P00403,O95202,O75964
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
448,161,418,138,71,361,136,75,338,181,150,22,216,155,31
|
2671,31,155,216,361,1134,752,1790,338,136,2092,1846,2639,181,1997,1795,1797,1617,2864,448,3131,3156,1199,418,466,1111,161,150,138,75,1599,22,1980,71
|
-0.7760255732552376,3.0502155042807657,1.8243030426289284,1.5248183397306079,1.0384916258428032,0.17094088359372295,0.44720170401297976,-0.21241421080737602,1.1013384647454063,1.9329933181047383,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,1.6858254775131012,-0.31690808027229783,-0.21241421080737602,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,0.8737391734444331,-1.7850748625508288,-2.0464349065431278,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.19322985148629535,1.801854471157927,1.8465093473865353,1.9329933181047383,2.5291039002629425,-0.08691226787820137,3.143317850644801,-0.2904304927178063,2.582335824717171
| 3,193
|
Secondary alcohol metabolic process
| 20
| 44
| 2.888084
| 0.003876
|
Q9BQE5,P49748,Q14739,Q14534,O75874,Q16850,P35610,Q15800,Q15125,Q8WTV0,P16435,P48735,P05067,Q15392,Q14849,O75845,P48449,Q9UBM7,P04035,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
6,391,147,403,277,158,288,35,294,43,299,314,438,63,74,224,226,370,245,122
|
858,2263,224,277,2311,1787,245,122,438,1709,2401,299,2607,3113,288,581,3000,226,314,391,3058,1507,1455,2746,457,1952,2825,2913,403,147,74,1411,294,2874,63,921,35,158,2328,43,3009,6,370,1695
|
0.36520852896444506,-0.4809780479553145,1.4858962903240147,1.3088453672804772,-0.5092252179873332,-0.21241421080737602,1.419454626258951,2.153135324237049,0.8907287812193003,-0.16155054834083413,-0.5665281275626076,1.2368621349000533,-0.7146987125093559,-1.661294066844009,1.280324185022697,0.6601866548649779,-1.2422071670625843,1.4858962903240147,1.1776036696350574,0.9739374379111466,-1.3886547156284181,-0.03822288271037234,-0.014190283332690111,-0.8385853324054076,0.8566305867164241,-0.2904304927178063,-0.934824649241834,-1.0678476456651755,0.9575234066599015,1.8684775279957868,2.536807538431712,0.009638014956759703,1.2514414118114898,-1.00064563472387,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,-0.5092252179873332,2.871125247428219,-1.2422071670625843,3.5925647235517952,1.0225160037257737,-0.13645324700708894
| 3,193
|
Mitochondrial respiratory chain complex assembly
| 16
| 36
| 2.886297
| 0.003898
|
P47985,O43676,O95831,Q69YU5,Q9P0J0,Q9Y512,Q9Y2R0,O43819,Q6DKK2,Q15070,O95168,O75306,Q9BRT2,Q9BSK2,Q9H061,Q96CU9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
448,34,194,8,201,332,44,514,363,48,593,205,630,212,57,126
|
2134,34,514,1443,205,1942,1026,593,2350,194,3070,448,1583,2868,48,2416,1209,8,363,1553,2832,1257,126,630,1427,212,2169,57,1642,719,2175,201,1230,44,332,649
|
-0.39780592754705757,2.9927281115085713,0.7514043268649677,-0.014190283332690111,1.5503857345605445,-0.2904304927178063,0.23726642403703146,0.6415400506909451,-0.5377405503528547,1.6375613175769943,-1.426290709801661,0.8737391734444331,-0.08691226787820137,-1.00064563472387,2.800152733484291,-0.5665281275626076,0.12580968009238108,3.5371028334084,1.0384916258428032,-0.062462590653624604,-0.934824649241834,0.10296255264400622,2.09550477869399,0.6038310370230041,0.009638014956759703,1.5376396248754793,-0.39780592754705757,2.6699756767430465,-0.11157482962869282,0.48725623745593405,-0.39780592754705757,1.6006322940022837,0.12580968009238108,2.8520707218101506,1.1321439407679112,0.5847653265563068
| 3,193
|
ER-Golgi transport
| 21
| 51
| 2.878984
| 0.00399
|
P24390,Q9NR31,P51572,P61923,P61019,P62820,Q15363,O43731,P49755,Q12981,Q15437,P55735,Q9Y678,P84085,Q9Y282,O95197,Q9HCU5,O95249,O15498,Q9P2W9,Q8N6H7
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
2,523,141,657,656,531,29,36,417,420,693,440,710,458,85,86,744,348,604,100,500
|
2635,1394,604,2304,1837,36,2137,1574,2447,86,348,1194,942,1169,2,990,1069,867,417,141,2504,2267,2321,2547,440,656,657,531,458,420,1723,29,998,693,1172,737,1633,1116,500,1679,1259,1681,2168,744,523,100,1933,85,986,795,710
|
-0.7452104629394918,0.009638014956759703,0.6227553904440447,-0.5092252179873332,-0.23818692761586824,2.96913415144942,-0.39780592754705757,-0.08691226787820137,-0.5955921179420027,2.4176108705977826,1.070123936480939,0.12580968009238108,0.30200233977580343,0.1484683010782358,3.7462657069794476,0.259018664523886,0.21533758545793177,0.36520852896444506,0.9243562959106226,1.9223825076951602,-0.6249367779380635,-0.4809780479553145,-0.5092252179873332,-0.6545664545020534,0.8907287812193003,0.5655565678430635,0.5655565678430635,0.7334243460639536,0.8566305867164241,0.9243562959106226,-0.16155054834083413,3.078186020550252,0.259018664523886,0.5267030007716262,0.1484683010782358,0.46730587199900714,-0.11157482962869282,0.19322985148629535,0.7869794546562088,-0.13645324700708894,0.10296255264400622,-0.13645324700708894,-0.39780592754705757,0.46730587199900714,0.7514043268649677,2.3075717767503545,-0.26419124276665046,2.4339675988258307,0.28059656391052684,0.42694183408394704,0.5070546681307051
| 3,193
|
Active ion transmembrane transporter activity
| 24
| 41
| 2.871294
| 0.004088
|
Q15043,P55011,P13073,Q7KZN9,Q9UDW1,P41440,Q9Y6M7,O95202,Q9H2J7,P16615,P51798,P47985,Q96ES6,P20020,Q9BXP2,P05023,P12235,Q9HD20,P61421,P00403,P12236,P53007,P08195,P05141
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
256,636,136,150,22,654,151,155,289,300,184,448,75,580,475,712,338,87,466,216,217,730,727,361
|
155,216,712,2449,361,1134,727,752,1790,338,217,136,300,580,2092,1846,2639,1795,888,1617,2864,654,448,3156,184,730,636,466,994,1111,870,256,150,75,475,289,1599,87,22,1980,151
|
1.8243030426289284,1.5248183397306079,0.48725623745593405,-0.5955921179420027,1.0384916258428032,0.17094088359372295,0.46730587199900714,0.44720170401297976,-0.21241421080737602,1.1013384647454063,1.5248183397306079,1.9329933181047383,1.2368621349000533,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,-0.21241421080737602,0.3443061993948582,-0.11157482962869282,-1.00064563472387,0.5655565678430635,0.8737391734444331,-2.0464349065431278,1.6738619652882785,0.46730587199900714,0.5847653265563068,0.8394016868466264,0.259018664523886,0.19322985148629535,0.36520852896444506,1.392310058750564,1.8465093473865353,2.5291039002629425,0.8394016868466264,1.280324185022697,-0.08691226787820137,2.4176108705977826,3.143317850644801,-0.2904304927178063,1.8465093473865353
| 3,193
|
Abnormal circulating lipid concentration
| 28
| 79
| 2.859998
| 0.004236
|
P23786,P22830,Q9Y5L0,P50402,P49748,Q14739,Q9UJS0,Q15800,O43772,Q15125,P06280,O95470,Q8N511,P31751,Q15392,Q9NZJ7,O75381,P07602,Q9BV10,P61916,O75844,P42858,Q9BTV4,O75845,Q15904,Q9NVI7,Q9UBM7,Q9Y4P3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,260,397,266,391,147,428,35,162,294,298,171,49,313,63,191,193,72,199,457,81,341,483,224,230,369,370,253
|
1393,3012,748,162,193,1610,606,81,224,1026,171,1708,298,1318,72,1032,3055,260,4,570,1105,313,3113,2818,1358,3125,581,582,973,1618,341,2866,867,391,266,1853,2911,1324,1542,2616,2409,1800,457,2506,1906,2009,2102,489,759,3163,2691,147,1810,294,63,921,35,230,923,2328,3158,1339,49,2698,877,1681,1683,483,199,1642,1183,369,191,370,2339,428,937,253,397
|
0.009638014956759703,-1.2782188724392092,0.44720170401297976,1.7905380137060627,1.6375613175769943,-0.11157482962869282,0.6227553904440447,2.4501778760429596,1.4858962903240147,0.23726642403703146,1.744645033106282,-0.16155054834083413,1.2368621349000533,0.0566926794738131,2.5672903217950718,0.23726642403703146,-1.3886547156284181,1.3786129091151909,3.6003046943759847,0.6786968138424812,0.19322985148629535,1.1776036696350574,-1.661294066844009,-0.934824649241834,0.03326476765043723,-1.743326090815665,0.6601866548649779,0.6601866548649779,0.28059656391052684,-0.11157482962869282,1.1013384647454063,-1.00064563472387,0.36520852896444506,0.9739374379111466,1.3648314259575298,-0.23818692761586824,-1.0678476456651755,0.0566926794738131,-0.062462590653624604,-0.7146987125093559,-0.5665281275626076,-0.21241421080737602,0.8566305867164241,-0.6249367779380635,-0.26419124276665046,-0.31690808027229783,-0.37059222129993374,0.8045775073895869,0.44720170401297976,-2.1845722045277824,-0.7760255732552376,1.8684775279957868,-0.21241421080737602,1.2514414118114898,2.6339966056994,0.32323817115644027,2.975065555239934,1.4595591237186676,0.32323817115644027,-0.5092252179873332,-2.1379443966160254,0.0566926794738131,2.7869149799952893,-0.7760255732552376,0.36520852896444506,-0.13645324700708894,-0.13645324700708894,0.8220511190203319,1.6130128562407051,-0.11157482962869282,0.1484683010782358,1.0225160037257737,1.6497305064842487,1.0225160037257737,-0.5092252179873332,0.9243562959106226,0.32323817115644027,1.4059236947909328,0.9739374379111466
| 3,193
|
Serine hydrolase activity
| 9
| 17
| 2.852343
| 0.00434
|
Q9H3G5,O14773,Q9HB40,Q4J6C6,P67812,P42785,Q16740,O75976,P10619
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
38,264,42,235,172,18,185,437,127
|
264,800,437,127,1539,2358,1711,18,2936,1402,487,172,185,235,625,38,42
|
1.3648314259575298,0.40652433044515934,0.8907287812193003,2.0857311239846426,-0.062462590653624604,-0.5377405503528547,-0.16155054834083413,3.226034750624375,-1.101981072569348,0.009638014956759703,0.8045775073895869,1.7330122185385242,1.6738619652882785,1.446271558144171,0.6038310370230041,2.926986348323763,2.8899600348937455
| 3,193
|
Mitochondrial membrane organization
| 21
| 47
| 2.847067
| 0.004412
|
P52789,Q9NVH1,P45880,Q9NS69,P17152,O95202,O14737,Q5XKP0,Q9H3K2,Q15070,O60313,Q13505,Q6UXV4,Q8IWA4,Q9P0J0,Q9Y512,Q9BUR5,P12235,Q16611,P05141,Q8WWC4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
516,270,15,16,529,155,408,549,302,48,430,51,449,328,201,332,335,338,355,361,502
|
1313,408,430,1610,1316,2735,155,2140,361,1063,1841,338,529,2894,1657,2543,3155,3000,15,2685,2867,516,51,48,355,660,557,1295,549,449,328,1375,2160,502,2163,335,302,16,270,698,201,1310,1230,1019,332,1703,1272
|
0.0566926794738131,0.9409967716069575,0.9076007240012801,-0.11157482962869282,0.0566926794738131,-0.8385853324054076,1.8243030426289284,-0.39780592754705757,1.0384916258428032,0.21533758545793177,-0.23818692761586824,1.1013384647454063,0.7334243460639536,-1.034071137875609,-0.13645324700708894,-0.6545664545020534,-2.0464349065431278,-1.2422071670625843,3.285196134499565,-0.7760255732552376,-1.00064563472387,0.7514043268649677,2.746560633651398,2.800152733484291,1.0543605595517835,0.5655565678430635,0.6970721128067479,0.07992440556882748,0.7153141117668748,0.8737391734444331,1.1321439407679112,0.03326476765043723,-0.39780592754705757,0.7869794546562088,-0.39780592754705757,1.1167917984678513,1.2221896821440608,3.2657379732892013,1.3509647782580774,0.5267030007716262,1.6006322940022837,0.07992440556882748,0.12580968009238108,0.259018664523886,1.1321439407679112,-0.13645324700708894,0.10296255264400622
| 3,193
|
secondary carrier transporter
| 10
| 14
| 2.844896
| 0.004443
|
Q15043,Q8TB61,Q9BQT8,Q96ES6,Q9BXP2,Q9UBX3,Q9Y6M7,O75746,O95202,Q9UJS0
|
Functions
|
Panther Protein class
|
panther_protein_class
|
256,101,238,75,475,54,151,527,155,428
|
527,155,636,870,256,954,101,75,238,475,1599,54,428,151
|
0.7334243460639536,1.8243030426289284,0.5847653265563068,0.36520852896444506,1.392310058750564,0.30200233977580343,2.2988294808347165,2.5291039002629425,1.446271558144171,0.8394016868466264,-0.08691226787820137,2.732890881137026,0.9243562959106226,1.8465093473865353
| 3,193
|
Organic acid transmembrane transporter activity
| 17
| 20
| 2.836024
| 0.004568
|
Q15758,P08183,Q9H2J7,Q96NB2,Q9H9B4,P08195,Q02978,P53985,Q9Y619,P33527,Q9BQT8,Q9H2D1,Q9UBX3,P41440,O75746,Q9UJS0,P53007
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
899,129,289,677,879,727,870,169,239,888,238,47,54,654,527,428,730
|
2181,527,129,727,888,654,730,169,870,899,954,677,238,47,289,1599,879,54,428,239
|
-0.4252722805882104,0.7334243460639536,2.0361169935164405,0.46730587199900714,0.3443061993948582,0.5655565678430635,0.46730587199900714,1.7677180561785404,0.36520852896444506,0.3443061993948582,0.30200233977580343,0.5462030417796385,1.446271558144171,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,2.732890881137026,0.9243562959106226,1.446271558144171
| 3,193
|
Metal ion homeostasis
| 30
| 79
| 2.835256
| 0.004579
|
Q8NE01,Q15043,P02786,P51572,P09601,P78417,Q9HC07,Q8IYU8,O95202,Q96A33,Q9BPX6,O75027,P16615,Q8N511,P05067,P30519,Q9Y487,O76024,Q9BXP2,Q9UM00,Q9HD20,P42858,P61421,P62942,Q16611,Q15904,Q8TAD4,Q7L0J3,Q8WWC4,Q6P4Q7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,256,265,141,17,145,146,410,155,284,297,170,300,49,438,69,71,454,475,214,87,341,466,481,355,230,105,108,502,375
|
1313,1274,1191,514,2264,801,170,1026,3153,454,155,2496,265,3144,2535,712,2449,438,1788,726,2736,802,17,1752,2452,300,1944,864,580,1280,3119,3087,69,3043,2864,341,141,2615,2004,636,466,1623,481,145,994,1717,2551,2689,2273,1043,256,2157,230,355,660,375,108,2831,410,49,2777,128,876,105,502,284,1969,601,297,475,1383,1774,146,87,824,214,71,1019,648
|
0.0566926794738131,0.07992440556882748,0.12580968009238108,0.7514043268649677,-0.4809780479553145,0.40652433044515934,1.744645033106282,0.23726642403703146,-2.0464349065431278,0.8566305867164241,1.8243030426289284,-0.6249367779380635,1.3648314259575298,-1.9133658565796359,-0.6545664545020534,0.48725623745593405,-0.5955921179420027,0.8907287812193003,-0.21241421080737602,0.46730587199900714,-0.8385853324054076,0.40652433044515934,3.250973747172662,-0.18686982059176915,-0.5955921179420027,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,0.07992440556882748,-1.7020688805675812,-1.5028434769808663,2.589810382359061,-1.3514355919674153,-1.00064563472387,1.1013384647454063,1.9223825076951602,-0.7146987125093559,-0.31690808027229783,0.5847653265563068,0.8394016868466264,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,-0.16155054834083413,-0.6545664545020534,-0.7760255732552376,-0.4809780479553145,0.23726642403703146,1.392310058750564,-0.39780592754705757,1.4595591237186676,1.0543605595517835,0.5655565678430635,1.006432544850282,2.245500235348313,-0.934824649241834,0.9409967716069575,2.7869149799952893,-0.8703399800828923,2.075908277865556,0.36520852896444506,2.2812210779922095,0.7869794546562088,1.2946295225860096,-0.2904304927178063,0.6415400506909451,1.2514414118114898,0.8394016868466264,0.03326476765043723,-0.18686982059176915,1.9009921408923331,2.4176108705977826,0.40652433044515934,1.5376396248754793,2.582335824717171,0.259018664523886,0.5847653265563068
| 3,193
|
Carboxylic acid transport
| 25
| 33
| 2.830446
| 0.004648
|
Q15758,P55011,P33527,P28288,Q8TDW0,P41440,O75915,O75746,Q9UJS0,Q9H2J7,Q96NB2,P53985,Q15042,Q9H2D1,Q9UBX3,Q9NZJ7,P07602,P53007,Q9H9B4,O60831,P08195,Q02978,Q9Y619,Q9BQT8,Q7L0J3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
899,636,888,515,929,654,528,527,428,289,677,169,814,47,54,191,72,730,879,478,727,870,239,238,108
|
2181,1571,478,527,528,1889,2351,72,727,1710,515,888,654,730,169,636,3114,870,814,899,954,108,929,677,238,47,289,1599,879,191,54,428,239
|
-0.4252722805882104,-0.08691226787820137,0.8220511190203319,0.7334243460639536,0.7334243460639536,-0.26419124276665046,-0.5377405503528547,2.5672903217950718,0.46730587199900714,-0.16155054834083413,0.7514043268649677,0.3443061993948582,0.5655565678430635,0.46730587199900714,1.7677180561785404,0.5847653265563068,-1.661294066844009,0.36520852896444506,0.40652433044515934,0.3443061993948582,0.30200233977580343,2.245500235348313,0.32323817115644027,0.5462030417796385,1.446271558144171,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,1.6497305064842487,2.732890881137026,0.9243562959106226,1.446271558144171
| 3,193
|
Golgi associated vesicle
| 11
| 27
| 2.829311
| 0.004665
|
P24390,O43731,P49755,P11717,O95782,Q8N511,P61923,Q9BVK6,P05067,Q15363,Q9Y3B3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,36,417,568,485,49,657,444,438,29,30
|
2635,36,1705,485,438,1990,568,2,990,1069,417,1454,2504,2267,1901,1247,657,1625,1906,29,49,1259,444,1057,1933,30,710
|
-0.7452104629394918,2.96913415144942,-0.16155054834083413,0.8045775073895869,0.8907287812193003,-0.31690808027229783,0.6786968138424812,3.7462657069794476,0.259018664523886,0.21533758545793177,0.9243562959106226,-0.014190283332690111,-0.6249367779380635,-0.4809780479553145,-0.26419124276665046,0.10296255264400622,0.5655565678430635,-0.11157482962869282,-0.26419124276665046,3.078186020550252,2.7869149799952893,0.10296255264400622,0.8907287812193003,0.23726642403703146,-0.26419124276665046,3.067058131253242,0.5070546681307051
| 3,193
|
Membrane lipid catabolic process
| 8
| 11
| 2.814364
| 0.004887
|
P06865,P06280,O95470,P17900,P04066,P50897,Q13510,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
293,298,171,234,400,19,116,122
|
171,122,400,298,293,726,234,19,116,442,707
|
1.744645033106282,2.153135324237049,0.9575234066599015,1.2368621349000533,1.2514414118114898,0.46730587199900714,1.446271558144171,3.2108682288698214,2.1998773817605315,0.8907287812193003,0.5070546681307051
| 3,193
|
Disproportionate short stature
| 13
| 29
| 2.811421
| 0.004932
|
P10644,Q7LGA3,Q9UHX1,Q15125,Q9BV10,P16278,Q9UBM7,Q14739,Q8WVQ1,P42345,Q03164,Q15392,Q96HA7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
225,131,37,294,199,11,370,147,311,409,60,63,319
|
1022,578,2981,1102,225,11,2932,1712,409,1069,60,3163,1631,147,2325,294,63,432,1082,131,842,1214,311,2597,319,575,199,370,37
|
0.23726642403703146,0.6601866548649779,-1.2065841027857491,0.19322985148629535,1.4858962903240147,3.418959561273887,-1.101981072569348,-0.16155054834083413,0.9409967716069575,0.21533758545793177,2.648478537565285,-2.1845722045277824,-0.11157482962869282,1.8684775279957868,-0.5092252179873332,1.2514414118114898,2.6339966056994,0.9076007240012801,0.21533758545793177,1.985222235335816,0.38594722827302785,0.12580968009238108,1.1925614229636166,-0.6844855875507391,1.162548846164761,0.6786968138424812,1.6130128562407051,1.0225160037257737,2.9330756917337433
| 3,193
|
Ion transmembrane transport
| 64
| 154
| 2.808139
| 0.004983
|
Q15043,P08183,P21796,P27105,P13073,Q9C0H2,Q6P4A7,P45880,P78417,Q9HC07,Q06787,Q9UDW1,P61619,Q7KZN9,O75915,Q9Y6M7,O95202,Q12959,Q9HC21,Q8IYU8,O75964,Q9UJS0,Q13423,Q9H2J7,O43772,Q9BPX6,P56385,Q9NW15,P53985,O75027,P16615,P46934,Q9H2D1,Q70HW3,Q14728,P24539,Q9UBX3,Q9UHG3,P51798,P05067,P47985,Q96ES6,Q9BXP2,O75844,P12235,Q9UM00,Q9HD20,P42858,P00403,P12236,P61421,Q96GC9,P62942,Q16611,O60831,Q8TB61,Q8TAD4,Q9Y619,Q9BQT8,P05141,Q8WWC4,Q9Y277,Q6P4Q7,O43808
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
256,129,7,137,136,13,142,15,145,146,532,22,530,150,528,151,155,279,405,410,31,428,161,289,162,297,418,168,169,170,300,416,47,50,305,181,54,59,184,438,448,75,475,81,338,214,87,341,216,217,466,220,481,355,478,101,105,239,238,361,502,247,375,505
|
2964,1234,2181,748,162,505,553,2264,478,170,2887,1443,1493,2788,527,81,528,2671,31,155,1751,216,712,2449,438,361,2351,1134,1988,826,2736,129,727,752,3092,1790,1709,338,217,136,300,1944,864,580,2092,1846,2639,2956,7,181,1997,137,3119,2894,3043,1795,888,1797,1617,2864,654,341,15,416,1661,448,3131,777,3156,184,730,169,2004,636,1199,418,466,530,1623,481,145,994,1111,1717,870,2463,532,2648,2551,279,161,714,2273,2691,305,1808,2853,256,2157,899,355,142,375,50,150,2831,410,2855,2777,876,105,101,929,502,1736,75,220,1969,677,3098,678,2381,297,238,1427,1054,475,13,1973,1383,47,289,1599,879,146,405,87,1057,904,168,54,22,1696,59,1980,428,824,214,247,2083,1019,239,2443,151
|
-1.1713430341599453,0.10296255264400622,-0.4252722805882104,0.44720170401297976,1.7905380137060627,0.7692555416447295,0.6970721128067479,-0.4809780479553145,0.8220511190203319,1.744645033106282,-1.034071137875609,-0.014190283332690111,-0.03822288271037234,-0.902417991440706,0.7334243460639536,2.4501778760429596,0.7334243460639536,-0.7760255732552376,3.0502155042807657,1.8243030426289284,-0.18686982059176915,1.5248183397306079,0.48725623745593405,-0.5955921179420027,0.8907287812193003,1.0384916258428032,-0.5377405503528547,0.17094088359372295,-0.31690808027229783,0.38594722827302785,-0.8385853324054076,2.0361169935164405,0.46730587199900714,0.44720170401297976,-1.5417758052175927,-0.21241421080737602,-0.16155054834083413,1.1013384647454063,1.5248183397306079,1.9329933181047383,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,-1.1364774707508174,3.5491802513502524,1.6858254775131012,-0.31690808027229783,1.9329933181047383,-1.7020688805675812,-1.034071137875609,-1.3514355919674153,-0.21241421080737602,0.3443061993948582,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,0.5655565678430635,1.1013384647454063,3.285196134499565,0.9243562959106226,-0.13645324700708894,0.8737391734444331,-1.7850748625508288,0.42694183408394704,-2.0464349065431278,1.6738619652882785,0.46730587199900714,1.7677180561785404,-0.31690808027229783,0.5847653265563068,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.7334243460639536,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,0.19322985148629535,-0.16155054834083413,0.36520852896444506,-0.5955921179420027,0.7334243460639536,-0.7452104629394918,-0.6545664545020534,1.3088453672804772,1.801854471157927,0.48725623745593405,-0.4809780479553145,-0.7760255732552376,1.207423100369303,-0.21241421080737602,-0.9675653554604676,1.392310058750564,-0.39780592754705757,0.3443061993948582,1.0543605595517835,1.9117156067218775,1.006432544850282,2.760120300435202,1.8465093473865353,-0.934824649241834,0.9409967716069575,-0.9675653554604676,-0.8703399800828923,0.36520852896444506,2.2812210779922095,2.2988294808347165,0.32323817115644027,0.7869794546562088,-0.16155054834083413,2.5291039002629425,1.5248183397306079,-0.2904304927178063,0.5462030417796385,-1.5417758052175927,0.5462030417796385,-0.5377405503528547,1.2514414118114898,1.446271558144171,0.009638014956759703,0.23726642403703146,0.8394016868466264,3.351325980333631,-0.2904304927178063,0.03326476765043723,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,1.9009921408923331,0.9575234066599015,2.4176108705977826,0.23726642403703146,0.3443061993948582,1.7791593908234755,2.732890881137026,3.143317850644801,-0.13645324700708894,2.6556741514333573,-0.2904304927178063,0.9243562959106226,0.40652433044515934,1.5376396248754793,1.419454626258951,-0.3436274762646461,0.259018664523886,1.446271558144171,-0.5665281275626076,1.8465093473865353
| 3,193
|
Protein transporter activity
| 9
| 13
| 2.797369
| 0.005152
|
O60830,Q99595,P49755,Q8NBU5,Q9NS69,O14925,Q9HD20,P61619,Q15388
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,3,417,628,16,211,87,530,280
|
211,0,1316,651,417,530,280,628,3,87,16,853,1703
|
1.5376396248754793,4.042548479567164,0.0566926794738131,0.5655565678430635,0.9243562959106226,0.7334243460639536,1.3088453672804772,0.6038310370230041,3.6753208773984025,2.4176108705977826,3.2657379732892013,0.38594722827302785,-0.13645324700708894
| 3,193
|
Organelle subcompartment
| 157
| 357
| 2.789702
| 0.005276
|
P24390,Q9P035,Q9BQE5,Q92643,P43307,Q13724,Q14108,P09601,Q15005,P61619,O75915,Q99720,Q8N0U8,O00461,Q15363,Q9Y3B3,Q00765,Q5BJF2,Q15382,P56377,Q15800,O43731,Q8N511,O43865,Q9H2M9,Q96HY6,Q15392,P11717,Q15629,P30519,Q14849,O75844,Q9Y282,Q9HD20,O95197,Q86UE4,Q06136,Q9P2W9,Q8TB61,O60499,Q9NQC3,Q86XL3,Q03518,Q9UKR5,P04062,P51648,O60725,P51572,Q96A57,Q9HC07,Q14739,Q96KC8,Q9UBV2,Q9BRR6,Q16850,Q96G23,Q9BUN8,O95470,P67812,Q86YN1,Q5VUD6,Q8N2H4,Q9Y5M8,Q9BV10,Q8N2K0,P46977,Q9UM00,Q96GC9,P07099,O75845,P48449,Q8TCT9,Q969E2,Q07065,Q15904,Q53GQ0,Q4J6C6,P04439,P04035,Q9Y4P3,Q9Y3A3,P53367,P38435,P53365,Q8IV08,O15260,P50402,O15127,Q12959,Q96RL7,Q9NZ08,Q96A33,Q70UQ0,P57088,P35610,Q96L58,Q15125,P16615,P16435,Q6NUM9,Q9Y5X1,O15269,Q8WVQ1,Q9BT22,P35613,Q8NF37,Q12893,Q2TAA5,Q9UBU6,Q6NUQ4,Q9NPA0,P52292,Q9BUR5,Q92604,Q9NZ01,O95249,Q99442,Q13190,O00443,O00767,Q16706,Q99640,Q9H490,Q9UBM7,O00264,O43852,O95864,Q6UWP7,Q96PC5,Q7Z6M1,Q14534,A1L0T0,P42345,Q9H4A6,Q9H3N1,P49755,Q12981,O95674,Q9BVK6,Q99735,P55735,P06493,P05067,O15126,P10321,O76024,Q96S66,Q8NHH9,Q7Z3C6,O14828,P62942,Q12907,Q86UL3,Q10471,Q10713,Q9Y3A6,Q8N5M9
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,524,6,519,10,517,14,17,533,530,528,26,27,28,29,30,546,32,548,545,35,36,49,553,577,575,63,568,64,69,74,81,85,87,86,92,99,100,101,103,113,112,111,115,122,130,140,141,143,146,147,148,154,153,158,159,165,171,172,177,178,182,183,199,203,206,214,220,222,224,226,227,228,229,230,236,235,233,245,253,252,248,255,261,262,259,266,274,279,285,287,284,283,282,288,291,294,300,299,301,308,303,311,316,317,318,325,326,331,334,336,333,335,343,347,348,359,354,350,360,362,365,368,370,371,372,374,385,386,394,403,407,409,426,425,417,420,415,444,442,440,439,438,436,455,454,474,472,471,462,481,490,492,489,497,513,511
|
617,407,1352,371,1098,350,28,2605,360,1099,2635,798,462,771,1572,1394,436,274,259,303,1060,2304,800,36,1705,1492,372,553,1985,103,1396,140,1166,2137,2307,1355,1574,620,81,224,528,454,1317,2734,2311,1888,2447,86,348,2496,2185,171,1194,942,1750,415,374,2036,1787,1497,245,122,233,687,1030,438,439,222,2314,2352,1990,17,3092,455,568,2452,299,300,1066,1447,633,2956,1847,2931,2,1946,3087,865,2815,2843,2718,69,3043,2144,1579,990,288,317,581,255,1896,1897,409,10,2503,206,1069,226,1285,1241,867,1582,417,266,777,1454,756,141,130,1360,333,261,248,2504,2267,2321,2969,440,545,282,2233,3059,2147,1622,1901,1544,656,637,1247,1545,530,713,657,810,2150,481,2461,172,833,2238,994,1625,546,1906,1667,111,1954,99,229,2748,489,1910,497,1365,1407,325,490,279,420,354,1668,2273,2511,517,14,872,2365,838,403,147,674,74,2693,533,1549,814,2240,294,2157,29,548,63,998,693,64,921,35,230,362,2417,158,326,235,236,32,661,1172,178,1336,1211,1514,301,737,334,954,385,283,875,471,394,92,492,1338,112,177,262,817,2831,1732,27,182,203,49,2373,511,1554,318,1003,472,1175,2067,101,1048,1341,587,2594,227,929,1865,1214,1259,311,1638,877,1215,1818,343,1519,519,2332,228,1683,1342,284,143,1640,1050,159,220,1969,575,148,291,1347,386,285,1971,474,359,365,1824,26,442,2599,2381,6,153,2025,2120,316,641,631,165,335,199,1054,3142,444,1307,666,1429,1738,1973,961,577,425,368,426,1008,1183,1974,1092,146,744,87,880,336,113,2292,645,682,707,347,287,524,909,2256,2128,100,1933,1602,370,331,154,853,615,1603,115,3137,214,855,2490,1700,85,986,938,884,252,513,30,2963,253,183,308,3160,710,1833
|
0.6038310370230041,0.9409967716069575,0.03326476765043723,1.006432544850282,0.19322985148629535,1.0543605595517835,3.078186020550252,-0.7146987125093559,1.0384916258428032,0.19322985148629535,-0.7452104629394918,0.40652433044515934,0.8394016868466264,0.42694183408394704,-0.08691226787820137,0.009638014956759703,0.8907287812193003,1.3229726085415559,1.3786129091151909,1.207423100369303,0.21533758545793177,-0.5092252179873332,0.40652433044515934,2.96913415144942,-0.16155054834083413,-0.03822288271037234,1.006432544850282,0.6970721128067479,-0.31690808027229783,2.2812210779922095,0.009638014956759703,1.9223825076951602,0.1484683010782358,-0.39780592754705757,-0.5092252179873332,0.03326476765043723,-0.08691226787820137,0.6038310370230041,2.4501778760429596,1.4858962903240147,0.7334243460639536,0.8566305867164241,0.0566926794738131,-0.8385853324054076,-0.5092252179873332,-0.26419124276665046,-0.5955921179420027,2.4176108705977826,1.070123936480939,-0.6249367779380635,-0.4252722805882104,1.744645033106282,0.12580968009238108,0.30200233977580343,-0.18686982059176915,0.9243562959106226,1.006432544850282,-0.3436274762646461,-0.21241421080737602,-0.03822288271037234,1.419454626258951,2.153135324237049,1.446271558144171,0.5267030007716262,0.23726642403703146,0.8907287812193003,0.8907287812193003,1.4989473958627886,-0.5092252179873332,-0.5377405503528547,-0.31690808027229783,3.250973747172662,-1.5417758052175927,0.8566305867164241,0.6786968138424812,-0.5955921179420027,1.2368621349000533,1.2368621349000533,0.21533758545793177,-0.014190283332690111,0.5847653265563068,-1.1364774707508174,-0.23818692761586824,-1.101981072569348,3.7462657069794476,-0.2904304927178063,-1.5028434769808663,0.36520852896444506,-0.934824649241834,-0.9675653554604676,-0.8071488815311059,2.589810382359061,-1.3514355919674153,-0.39780592754705757,-0.08691226787820137,0.259018664523886,1.280324185022697,1.162548846164761,0.6601866548649779,1.392310058750564,-0.26419124276665046,-0.26419124276665046,0.9409967716069575,3.4750650461264545,-0.6249367779380635,1.5503857345605445,0.21533758545793177,1.4858962903240147,0.07992440556882748,0.10296255264400622,0.36520852896444506,-0.08691226787820137,0.9243562959106226,1.3648314259575298,0.42694183408394704,-0.014190283332690111,0.44720170401297976,1.9223825076951602,2.015915696016737,0.03326476765043723,1.1167917984678513,1.3786129091151909,1.4059236947909328,-0.6249367779380635,-0.4809780479553145,-0.5092252179873332,-1.1713430341599453,0.8907287812193003,0.7153141117668748,1.2946295225860096,-0.4529950413267082,-1.3886547156284181,-0.39780592754705757,-0.11157482962869282,-0.26419124276665046,-0.062462590653624604,0.5655565678430635,0.5847653265563068,0.10296255264400622,-0.062462590653624604,0.7334243460639536,0.48725623745593405,0.5655565678430635,0.40652433044515934,-0.39780592754705757,0.8220511190203319,-0.5955921179420027,1.7330122185385242,0.38594722827302785,-0.4529950413267082,0.259018664523886,-0.11157482962869282,0.7153141117668748,-0.26419124276665046,-0.13645324700708894,2.2364631467360248,-0.2904304927178063,2.3075717767503545,1.4595591237186676,-0.8385853324054076,0.8045775073895869,-0.26419124276665046,0.7869794546562088,0.03326476765043723,0.009638014956759703,1.1321439407679112,0.8045775073895869,1.3088453672804772,0.9243562959106226,1.0543605595517835,-0.13645324700708894,-0.4809780479553145,-0.6249367779380635,0.7514043268649677,3.309160878702859,0.36520852896444506,-0.5377405503528547,0.38594722827302785,0.9575234066599015,1.8684775279957868,0.5462030417796385,2.536807538431712,-0.7760255732552376,0.7334243460639536,-0.062462590653624604,0.40652433044515934,-0.4529950413267082,1.2514414118114898,-0.39780592754705757,3.078186020550252,0.7153141117668748,2.6339966056994,0.259018664523886,0.5267030007716262,2.62670988147732,0.32323817115644027,2.975065555239934,1.4595591237186676,1.0384916258428032,-0.5665281275626076,1.8243030426289284,1.1321439407679112,1.446271558144171,1.446271558144171,3.0502155042807657,0.5655565678430635,0.1484683010782358,1.6977216604154457,0.0566926794738131,0.12580968009238108,-0.03822288271037234,1.2221896821440608,0.46730587199900714,1.1167917984678513,0.30200233977580343,0.9902400838282385,1.2946295225860096,0.36520852896444506,0.8394016868466264,0.9739374379111466,2.359178009634381,0.8045775073895869,0.0566926794738131,2.2364631467360248,1.7095511162040427,1.3786129091151909,0.40652433044515934,-0.934824649241834,-0.16155054834083413,3.083720150229578,1.6858254775131012,1.575655220295083,2.7869149799952893,-0.5377405503528547,0.7692555416447295,-0.062462590653624604,1.162548846164761,0.259018664523886,0.8394016868466264,0.1484683010782358,-0.3436274762646461,2.2988294808347165,0.23726642403703146,0.0566926794738131,0.6601866548649779,-0.6844855875507391,1.472767115384539,0.32323817115644027,-0.23818692761586824,0.12580968009238108,0.10296255264400622,1.1925614229636166,-0.11157482962869282,0.36520852896444506,0.12580968009238108,-0.21241421080737602,1.1013384647454063,-0.03822288271037234,0.7514043268649677,-0.5092252179873332,1.472767115384539,-0.13645324700708894,0.0566926794738131,1.2946295225860096,1.9117156067218775,-0.11157482962869282,0.23726642403703146,1.8243030426289284,1.5248183397306079,-0.2904304927178063,0.6786968138424812,1.8575229481079278,1.2659284528512882,0.0566926794738131,0.9902400838282385,1.2946295225860096,-0.2904304927178063,0.8394016868466264,1.0543605595517835,1.0384916258428032,-0.21241421080737602,3.0892345539041384,0.8907287812193003,-0.6844855875507391,-0.5377405503528547,3.5925647235517952,1.8354362171377097,-0.31690808027229783,-0.37059222129993374,1.1776036696350574,0.5847653265563068,0.6038310370230041,1.7905380137060627,1.1167917984678513,1.6130128562407051,0.23726642403703146,-1.8700849622133329,0.8907287812193003,0.07992440556882748,0.5655565678430635,0.009638014956759703,-0.16155054834083413,-0.2904304927178063,0.30200233977580343,0.6786968138424812,0.9243562959106226,1.0225160037257737,0.9243562959106226,0.259018664523886,0.1484683010782358,-0.2904304927178063,0.21533758545793177,1.9009921408923331,0.46730587199900714,2.4176108705977826,0.36520852896444506,1.1167917984678513,2.2364631467360248,-0.4809780479553145,0.5847653265563068,0.5462030417796385,0.5070546681307051,1.0857828718447309,1.2946295225860096,0.7514043268649677,0.3443061993948582,-0.4529950413267082,-0.37059222129993374,2.3075717767503545,-0.26419124276665046,-0.08691226787820137,1.0225160037257737,1.1321439407679112,1.8354362171377097,0.38594722827302785,0.6227553904440447,-0.08691226787820137,2.2182584184461103,-1.8273246014917721,1.5376396248754793,0.38594722827302785,-0.5955921179420027,-0.13645324700708894,2.4339675988258307,0.28059656391052684,0.32323817115644027,0.36520852896444506,1.4059236947909328,0.7692555416447295,3.067058131253242,-1.1364774707508174,1.4059236947909328,1.6858254775131012,1.207423100369303,-2.1379443966160254,0.5070546681307051,-0.21241421080737602
| 3,193
|
Sphingolipid metabolism
| 7
| 12
| 2.785743
| 0.005341
|
Q06136,P06280,P16278,O95470,Q16880,Q13510,P04062
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
99,298,11,171,273,116,122
|
303,1060,619,171,122,298,2891,11,99,116,273,707
|
1.207423100369303,0.21533758545793177,0.6038310370230041,1.744645033106282,2.153135324237049,1.2368621349000533,-1.034071137875609,3.418959561273887,2.3075717767503545,2.1998773817605315,1.3370121237135937,0.5070546681307051
| 3,193
|
serine protease
| 8
| 18
| 2.785423
| 0.005346
|
Q9H3G5,Q8N2K0,Q9HB40,Q4J6C6,P67812,P42785,Q16740,P10619
|
Functions
|
Panther Protein class
|
panther_protein_class
|
38,203,42,235,172,18,185,127
|
264,800,565,127,2538,1539,2358,1711,18,2936,172,185,235,203,2959,38,42,2633
|
1.3648314259575298,0.40652433044515934,0.6786968138424812,2.0857311239846426,-0.6545664545020534,-0.062462590653624604,-0.5377405503528547,-0.16155054834083413,3.226034750624375,-1.101981072569348,1.7330122185385242,1.6738619652882785,1.446271558144171,1.575655220295083,-1.1364774707508174,2.926986348323763,2.8899600348937455,-0.7146987125093559
| 3,193
|
Clumsiness
| 9
| 22
| 2.781593
| 0.005409
|
O14773,P07602,O75503,O00165,Q13510,P42858,Q9NR77,Q15067,Q9NZJ7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
264,72,104,45,116,341,61,421,191
|
45,2086,264,1393,619,514,104,2450,72,2891,2610,1578,341,1328,116,421,1860,2246,424,61,191,1978
|
2.832792341598909,-0.37059222129993374,1.3648314259575298,0.009638014956759703,0.6038310370230041,0.7514043268649677,2.2812210779922095,-0.5955921179420027,2.5672903217950718,-1.034071137875609,-0.7146987125093559,-0.08691226787820137,1.1013384647454063,0.0566926794738131,2.1998773817605315,0.9243562959106226,-0.23818692761586824,-0.4529950413267082,0.9243562959106226,2.6412527563805264,1.6497305064842487,-0.2904304927178063
| 3,193
|
Sphingolipid biosynthetic process
| 8
| 14
| 2.779167
| 0.00545
|
Q06136,O95470,Q16880,Q99805,Q13510,O15269,P04062,Q96G23
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,171,273,367,116,303,122,159
|
303,1060,171,122,1847,99,116,273,1295,159,367,707,524,2256
|
1.207423100369303,0.21533758545793177,1.744645033106282,2.153135324237049,-0.23818692761586824,2.3075717767503545,2.1998773817605315,1.3370121237135937,0.07992440556882748,1.8243030426289284,1.0225160037257737,0.5070546681307051,0.7514043268649677,-0.4529950413267082
| 3,193
|
Abnormality of femur morphology
| 21
| 75
| 2.773437
| 0.005547
|
Q7LGA3,P16278,P04066,Q14739,Q96A33,Q96L58,Q9UHX1,P06280,P16435,Q8WVQ1,P51798,Q9NZJ7,Q96HA7,O95831,Q9Y487,P07602,Q9BV10,O75844,O00443,Q9Y619,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
131,11,400,147,284,291,37,298,299,311,184,191,319,194,71,72,199,81,350,239,122
|
1022,350,2605,2086,1393,650,1396,2981,1610,2183,1102,81,1707,194,2036,1708,122,400,2140,298,725,72,669,11,299,2956,1501,1136,3018,3155,2642,1069,184,1140,2770,636,2270,147,2325,1369,2915,432,2277,737,2878,131,2830,1146,842,2697,2974,1214,311,284,600,319,575,291,1347,1425,1426,199,1154,1481,1183,2783,746,1263,191,37,2218,2029,71,1647,239
|
0.23726642403703146,1.0543605595517835,-0.7146987125093559,-0.37059222129993374,0.009638014956759703,0.5655565678430635,0.009638014956759703,-1.2065841027857491,-0.11157482962869282,-0.4252722805882104,0.19322985148629535,2.4501778760429596,-0.16155054834083413,1.6375613175769943,-0.3436274762646461,-0.16155054834083413,2.153135324237049,0.9575234066599015,-0.39780592754705757,1.2368621349000533,0.46730587199900714,2.5672903217950718,0.5462030417796385,3.418959561273887,1.2368621349000533,-1.1364774707508174,-0.03822288271037234,0.17094088359372295,-1.2782188724392092,-2.0464349065431278,-0.7452104629394918,0.21533758545793177,1.6738619652882785,0.17094088359372295,-0.8703399800828923,0.5847653265563068,-0.4809780479553145,1.8684775279957868,-0.5092252179873332,0.03326476765043723,-1.0678476456651755,0.9076007240012801,-0.4809780479553145,0.46730587199900714,-1.00064563472387,1.985222235335816,-0.934824649241834,0.17094088359372295,0.38594722827302785,-0.7760255732552376,-1.1713430341599453,0.12580968009238108,1.1925614229636166,1.2946295225860096,0.6415400506909451,1.162548846164761,0.6786968138424812,1.2659284528512882,0.0566926794738131,0.009638014956759703,0.009638014956759703,1.6130128562407051,0.17094088359372295,-0.014190283332690111,0.1484683010782358,-0.8703399800828923,0.46730587199900714,0.10296255264400622,1.6497305064842487,2.9330756917337433,-0.4252722805882104,-0.31690808027229783,2.582335824717171,-0.11157482962869282,1.446271558144171
| 3,193
|
Nucleobase containing compound transmembrane transporter activity
| 8
| 13
| 2.760758
| 0.005767
|
Q99808,Q8TB61,P05141,Q9H2D1,P12235,Q9HC21,Q9BSK2,P12236
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
321,101,361,47,338,405,212,217
|
912,505,361,338,217,654,1171,1112,101,321,212,47,405
|
0.32323817115644027,0.7692555416447295,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.5655565678430635,0.1484683010782358,0.19322985148629535,2.2988294808347165,1.1473959441543768,1.5376396248754793,2.813285883739657,0.9575234066599015
| 3,193
|
Biliary tract abnormality
| 7
| 26
| 2.755765
| 0.005856
|
P07602,Q14108,P09601,Q14739,P04062,O95202,Q9NZJ7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
72,14,17,147,122,155,191
|
619,155,1168,1708,122,72,17,1710,2891,3100,1711,2685,1324,1141,497,2200,14,147,549,1967,1925,1223,191,231,1230,397
|
0.6038310370230041,1.8243030426289284,0.1484683010782358,-0.16155054834083413,2.153135324237049,2.5672903217950718,3.250973747172662,-0.16155054834083413,-1.034071137875609,-1.581156126510372,-0.16155054834083413,-0.7760255732552376,0.0566926794738131,0.17094088359372295,0.7869794546562088,-0.4252722805882104,3.309160878702859,1.8684775279957868,0.7153141117668748,-0.2904304927178063,-0.26419124276665046,0.12580968009238108,1.6497305064842487,1.4595591237186676,0.12580968009238108,0.9739374379111466
| 3,193
|
Endopeptidase activity
| 25
| 61
| 2.747044
| 0.006014
|
P28072,Q9BYT8,O14773,Q92643,P60900,Q99797,Q9NZ08,Q14674,P67812,Q16740,P28070,P49721,Q92542,O75844,Q99538,P42892,Q8TCT9,O43847,Q4J6C6,P53634,Q5JRX3,Q9UBR2,Q10713,P40818,P28074
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
381,521,264,519,402,411,287,547,172,185,570,65,329,81,346,91,227,605,235,487,625,244,497,622,495
|
264,800,605,2788,81,826,1539,1654,2402,970,775,3124,570,381,495,2358,2718,1711,622,2742,91,974,2936,2644,65,1663,1664,487,2987,402,172,497,780,547,2588,185,235,625,2109,1815,227,329,519,1767,1967,1866,2021,1262,932,1424,346,411,2564,521,287,1781,244,1438,647,1606,1019
|
1.3648314259575298,0.40652433044515934,0.6227553904440447,-0.902417991440706,2.4501778760429596,0.38594722827302785,-0.062462590653624604,-0.13645324700708894,-0.5665281275626076,0.28059656391052684,0.42694183408394704,-1.743326090815665,0.6786968138424812,0.9902400838282385,0.7869794546562088,-0.5377405503528547,-0.8071488815311059,-0.16155054834083413,0.6038310370230041,-0.8385853324054076,2.359178009634381,0.28059656391052684,-1.101981072569348,-0.7452104629394918,2.6193923777828645,-0.13645324700708894,-0.13645324700708894,0.8045775073895869,-1.2065841027857491,0.9575234066599015,1.7330122185385242,0.7869794546562088,0.42694183408394704,0.7153141117668748,-0.6844855875507391,1.6738619652882785,1.446271558144171,0.6038310370230041,-0.37059222129993374,-0.21241421080737602,1.472767115384539,1.1321439407679112,0.7514043268649677,-0.18686982059176915,-0.2904304927178063,-0.23818692761586824,-0.31690808027229783,0.10296255264400622,0.32323817115644027,0.009638014956759703,1.0857828718447309,0.9409967716069575,-0.6545664545020534,0.7514043268649677,1.2946295225860096,-0.18686982059176915,1.4329036514563958,0.009638014956759703,0.5847653265563068,-0.08691226787820137,0.259018664523886
| 3,193
|
Abnormal circulating cholesterol concentration
| 19
| 37
| 2.745815
| 0.006036
|
P50402,Q14739,Q9UJS0,Q15800,Q15125,Q8N511,Q15392,Q9NZJ7,P07602,Q9BV10,P38571,P61916,P42858,Q9BTV4,O75845,Q15904,Q10471,Q9NVI7,Q9UBM7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
266,147,428,35,294,49,63,191,72,199,582,457,341,483,224,230,489,369,370
|
3012,1610,224,1708,1318,72,3113,581,582,341,2866,266,2911,1800,457,1906,489,759,2691,147,294,63,921,35,230,2328,1339,49,2698,877,483,199,1183,369,191,370,428
|
-1.2782188724392092,-0.11157482962869282,1.4858962903240147,-0.16155054834083413,0.0566926794738131,2.5672903217950718,-1.661294066844009,0.6601866548649779,0.6601866548649779,1.1013384647454063,-1.00064563472387,1.3648314259575298,-1.0678476456651755,-0.21241421080737602,0.8566305867164241,-0.26419124276665046,0.8045775073895869,0.44720170401297976,-0.7760255732552376,1.8684775279957868,1.2514414118114898,2.6339966056994,0.32323817115644027,2.975065555239934,1.4595591237186676,-0.5092252179873332,0.0566926794738131,2.7869149799952893,-0.7760255732552376,0.36520852896444506,0.8220511190203319,1.6130128562407051,0.1484683010782358,1.0225160037257737,1.6497305064842487,1.0225160037257737,0.9243562959106226
| 3,193
|
Protein targeting to mitochondrion
| 19
| 48
| 2.735693
| 0.006225
|
O60830,Q99595,P51572,Q9NS69,Q15388,Q99797,O14737,Q8N4H5,O43615,O00165,Q9GZY8,P30536,O95831,Q9P0J0,Q9Y512,O14925,P55786,O95429,Q10713
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,3,141,16,280,411,408,41,414,45,312,58,194,201,332,211,218,373,497
|
45,2085,408,211,800,414,0,2788,1316,2735,2889,373,2907,194,651,1063,3129,1399,58,2543,867,2867,141,218,2849,497,280,1917,557,1295,625,1962,41,2832,2779,3,411,312,2253,16,201,1781,2921,1310,512,332,1703,1272
|
2.832792341598909,-0.37059222129993374,0.9409967716069575,1.5376396248754793,0.40652433044515934,0.9243562959106226,4.042548479567164,-0.902417991440706,0.0566926794738131,-0.8385853324054076,-1.034071137875609,1.006432544850282,-1.0678476456651755,1.6375613175769943,0.5655565678430635,0.21533758545793177,-1.7850748625508288,0.009638014956759703,2.6556741514333573,-0.6545664545020534,0.36520852896444506,-1.00064563472387,1.9223825076951602,1.5248183397306079,-0.9675653554604676,0.7869794546562088,1.3088453672804772,-0.26419124276665046,0.6970721128067479,0.07992440556882748,0.6038310370230041,-0.2904304927178063,2.8899600348937455,-0.934824649241834,-0.8703399800828923,3.6753208773984025,0.9409967716069575,1.1925614229636166,-0.4529950413267082,3.2657379732892013,1.6006322940022837,-0.18686982059176915,-1.0678476456651755,0.07992440556882748,0.7692555416447295,1.1321439407679112,-0.13645324700708894,0.10296255264400622
| 3,193
|
Organophosphate ester transmembrane transporter activity
| 8
| 11
| 2.734632
| 0.006245
|
Q99808,Q8TB61,P05141,Q9H2D1,P12235,Q9HC21,Q9BSK2,P12236
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
321,101,361,47,338,405,212,217
|
505,361,338,217,654,1112,101,321,212,47,405
|
0.7692555416447295,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.5655565678430635,0.19322985148629535,2.2988294808347165,1.1473959441543768,1.5376396248754793,2.813285883739657,0.9575234066599015
| 3,193
|
Nucleotide transmembrane transporter activity
| 8
| 11
| 2.734632
| 0.006245
|
Q99808,Q8TB61,P05141,Q9H2D1,P12235,Q9HC21,Q9BSK2,P12236
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
321,101,361,47,338,405,212,217
|
505,361,338,217,654,1112,101,321,212,47,405
|
0.7692555416447295,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.5655565678430635,0.19322985148629535,2.2988294808347165,1.1473959441543768,1.5376396248754793,2.813285883739657,0.9575234066599015
| 3,193
|
Nuclear inner membrane
| 7
| 19
| 2.731641
| 0.006302
|
Q9H1E5,Q5SNT2,P50402,O75844,Q14728,Q14739,Q99720
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
98,393,266,81,305,147,26
|
81,861,2315,1451,1505,266,2823,1404,2009,1460,305,147,1335,393,1146,26,483,98,683
|
2.4501778760429596,0.36520852896444506,-0.5092252179873332,-0.014190283332690111,-0.03822288271037234,1.3648314259575298,-0.934824649241834,0.009638014956759703,-0.31690808027229783,-0.014190283332690111,1.207423100369303,1.8684775279957868,0.0566926794738131,0.9739374379111466,0.17094088359372295,3.0892345539041384,0.8220511190203319,2.3162732124688055,0.5462030417796385
| 3,193
|
Cherry red spot of the macula
| 6
| 9
| 2.730959
| 0.006315
|
P07602,P16278,P17900,Q13510,P10619,Q9NZJ7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
72,11,234,116,127,191
|
293,72,726,127,2228,11,234,116,191
|
1.2514414118114898,2.5672903217950718,0.46730587199900714,2.0857311239846426,-0.4529950413267082,3.418959561273887,1.446271558144171,2.1998773817605315,1.6497305064842487
| 3,193
|
Golgi organization
| 25
| 59
| 2.717705
| 0.006574
|
O15260,Q9Y2L5,P61019,P50570,P62820,Q15363,Q9Y3B3,Q9H4A6,Q8IWJ2,P49755,Q14789,Q9BVK6,P48729,P06493,Q8NCM8,Q9Y6Y8,Q8NHH9,P42858,Q96GC9,Q9UID3,Q13190,Q9P2W9,Q12907,Q9BTU6,Q9Y3A6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
259,795,656,777,531,29,30,426,817,417,674,444,688,439,842,476,472,341,220,615,354,100,490,641,513
|
1099,1163,1440,1394,259,2304,2137,2307,1574,439,2892,1136,1852,1897,341,688,867,417,777,1622,656,531,2236,833,2100,490,354,674,29,1633,976,1962,817,842,472,2067,1048,1214,1215,1519,220,1347,2599,2381,641,444,426,2122,1008,1183,100,615,1484,2027,1700,795,513,30,476
|
0.19322985148629535,0.1484683010782358,-0.014190283332690111,0.009638014956759703,1.3786129091151909,-0.5092252179873332,-0.39780592754705757,-0.5092252179873332,-0.08691226787820137,0.8907287812193003,-1.034071137875609,0.17094088359372295,-0.23818692761586824,-0.26419124276665046,1.1013384647454063,0.5267030007716262,0.36520852896444506,0.9243562959106226,0.42694183408394704,-0.11157482962869282,0.5655565678430635,0.7334243460639536,-0.4529950413267082,0.38594722827302785,-0.37059222129993374,0.8045775073895869,1.0543605595517835,0.5462030417796385,3.078186020550252,-0.11157482962869282,0.28059656391052684,-0.2904304927178063,0.40652433044515934,0.38594722827302785,0.8394016868466264,-0.3436274762646461,0.23726642403703146,0.12580968009238108,0.12580968009238108,-0.03822288271037234,1.5248183397306079,0.0566926794738131,-0.6844855875507391,-0.5377405503528547,0.5847653265563068,0.8907287812193003,0.9243562959106226,-0.37059222129993374,0.259018664523886,0.1484683010782358,2.3075717767503545,0.6227553904440447,-0.014190283332690111,-0.31690808027229783,-0.13645324700708894,0.42694183408394704,0.7692555416447295,3.067058131253242,0.8394016868466264
| 3,193
|
Lipid droplet
| 12
| 31
| 2.712856
| 0.006671
|
Q8NF37,Q9H6V9,P48449,Q9H4M9,Q07065,Q96RL7,Q01105,P51572,Q8NBX0,Q99720,O43760,Q8NBQ5
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
318,96,226,452,229,285,488,141,21,26,125,550
|
2304,125,1985,1131,1750,1787,2576,1988,567,226,2047,1287,141,2969,488,229,814,921,1472,550,21,318,1215,1050,285,26,452,96,880,2441,1833
|
-0.5092252179873332,2.09550477869399,-0.31690808027229783,0.17094088359372295,-0.18686982059176915,-0.21241421080737602,-0.6844855875507391,-0.31690808027229783,0.6786968138424812,1.4858962903240147,-0.3436274762646461,0.07992440556882748,1.9223825076951602,-1.1713430341599453,0.8045775073895869,1.4595591237186676,0.40652433044515934,0.32323817115644027,-0.014190283332690111,0.7153141117668748,3.148622465340775,1.162548846164761,0.12580968009238108,0.23726642403703146,1.2946295225860096,3.0892345539041384,0.8737391734444331,2.324934091671502,0.36520852896444506,-0.5665281275626076,-0.21241421080737602
| 3,193
|
Transmembrane transport
| 91
| 211
| 2.712249
| 0.006683
|
O60830,Q99595,P23786,P21796,P52789,P28288,Q9C0H2,P45880,Q9NS69,Q06787,Q9UDW1,P61619,O75915,O75964,Q8WTV0,Q9H2D1,Q70HW3,Q9UBX3,Q9UHG3,Q15629,Q96ES6,O75844,Q9HD20,Q8TB61,Q8TAD4,Q7L0J3,Q03518,Q8IXU6,P04062,Q8NE01,P08183,P27105,P13073,Q6P4A7,P78417,Q9HC07,Q7KZN9,Q9Y6M7,O95202,Q13423,O43772,Q9NW15,P53985,O75027,Q9H2V7,P24539,P51798,O75381,O95831,O14925,Q9UM00,Q9BSK2,P00403,P12236,Q96GC9,Q9Y619,Q9BQT8,Q9Y277,P38435,Q15043,Q12959,Q15388,Q9H2J7,Q9BPX6,P16615,Q14728,P31751,Q99808,P12235,P42858,Q16625,Q16611,Q99442,P05141,Q6P4Q7,Q9HC21,Q8IYU8,Q99797,Q9UJS0,P49755,P56385,P46934,O43615,P05067,P47985,Q9BXP2,P61421,P62942,O60831,Q8WWC4,O43808
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,3,4,7,516,515,13,15,16,532,22,530,528,31,43,47,50,54,59,64,75,81,87,101,105,108,111,117,122,128,129,137,136,142,145,146,150,151,155,161,162,168,169,170,174,181,184,193,194,211,214,212,216,217,220,239,238,247,255,256,279,280,289,297,300,305,313,321,338,341,342,355,359,361,375,405,410,411,428,417,418,416,414,438,448,475,466,481,478,502,505
|
912,2604,2964,1234,2181,211,414,748,162,505,553,2264,0,478,170,2887,1443,1493,193,2788,527,81,528,2671,31,1316,155,1751,194,651,216,122,712,2449,438,361,2351,1788,1134,1988,826,1653,2736,129,727,752,3092,1790,3129,863,669,1709,338,217,136,300,1944,864,580,2092,1846,2639,2956,7,4,181,1997,137,3119,515,2894,3043,313,1795,1579,888,1797,1617,255,2864,654,341,15,416,1661,448,3131,417,2867,1853,777,3156,184,516,730,169,2004,636,1199,418,3059,2270,466,530,1623,481,145,994,1111,1717,870,111,2463,2197,532,2648,2551,279,161,714,2273,2691,305,1808,2853,256,2157,280,64,899,922,355,342,2327,557,1112,954,142,375,2973,50,150,108,3007,2831,117,410,2855,2832,2777,128,876,105,101,2594,929,43,502,1736,75,220,1969,677,359,3098,3,678,411,321,2381,297,238,1427,212,1054,475,2289,1429,13,1973,1383,47,289,174,1599,879,2253,146,405,87,1057,904,2808,16,168,54,22,853,1696,59,1980,428,824,1311,214,247,2083,1019,239,2443,151
|
0.32323817115644027,-0.7146987125093559,-1.1713430341599453,0.10296255264400622,-0.4252722805882104,1.5376396248754793,0.9243562959106226,0.44720170401297976,1.7905380137060627,0.7692555416447295,0.6970721128067479,-0.4809780479553145,4.042548479567164,0.8220511190203319,1.744645033106282,-1.034071137875609,-0.014190283332690111,-0.03822288271037234,1.6375613175769943,-0.902417991440706,0.7334243460639536,2.4501778760429596,0.7334243460639536,-0.7760255732552376,3.0502155042807657,0.0566926794738131,1.8243030426289284,-0.18686982059176915,1.6375613175769943,0.5655565678430635,1.5248183397306079,2.153135324237049,0.48725623745593405,-0.5955921179420027,0.8907287812193003,1.0384916258428032,-0.5377405503528547,-0.21241421080737602,0.17094088359372295,-0.31690808027229783,0.38594722827302785,-0.13645324700708894,-0.8385853324054076,2.0361169935164405,0.46730587199900714,0.44720170401297976,-1.5417758052175927,-0.21241421080737602,-1.7850748625508288,0.36520852896444506,0.5462030417796385,-0.16155054834083413,1.1013384647454063,1.5248183397306079,1.9329933181047383,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,-1.1364774707508174,3.5491802513502524,3.6003046943759847,1.6858254775131012,-0.31690808027229783,1.9329933181047383,-1.7020688805675812,0.7514043268649677,-1.034071137875609,-1.3514355919674153,1.1776036696350574,-0.21241421080737602,-0.08691226787820137,0.3443061993948582,-0.21241421080737602,-0.11157482962869282,1.392310058750564,-1.00064563472387,0.5655565678430635,1.1013384647454063,3.285196134499565,0.9243562959106226,-0.13645324700708894,0.8737391734444331,-1.7850748625508288,0.9243562959106226,-1.00064563472387,-0.23818692761586824,0.42694183408394704,-2.0464349065431278,1.6738619652882785,0.7514043268649677,0.46730587199900714,1.7677180561785404,-0.31690808027229783,0.5847653265563068,0.12580968009238108,0.9243562959106226,-1.3886547156284181,-0.4809780479553145,0.8394016868466264,0.7334243460639536,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,0.19322985148629535,-0.16155054834083413,0.36520852896444506,2.2364631467360248,-0.5955921179420027,-0.4252722805882104,0.7334243460639536,-0.7452104629394918,-0.6545664545020534,1.3088453672804772,1.801854471157927,0.48725623745593405,-0.4809780479553145,-0.7760255732552376,1.207423100369303,-0.21241421080737602,-0.9675653554604676,1.392310058750564,-0.39780592754705757,1.3088453672804772,2.62670988147732,0.3443061993948582,0.32323817115644027,1.0543605595517835,1.1013384647454063,-0.5092252179873332,0.6970721128067479,0.19322985148629535,0.30200233977580343,1.9117156067218775,1.006432544850282,-1.1713430341599453,2.760120300435202,1.8465093473865353,2.245500235348313,-1.2422071670625843,-0.934824649241834,2.1906198942531567,0.9409967716069575,-0.9675653554604676,-0.934824649241834,-0.8703399800828923,2.075908277865556,0.36520852896444506,2.2812210779922095,2.2988294808347165,-0.6844855875507391,0.32323817115644027,2.871125247428219,0.7869794546562088,-0.16155054834083413,2.5291039002629425,1.5248183397306079,-0.2904304927178063,0.5462030417796385,1.0543605595517835,-1.5417758052175927,3.6753208773984025,0.5462030417796385,0.9409967716069575,1.1473959441543768,-0.5377405503528547,1.2514414118114898,1.446271558144171,0.009638014956759703,1.5376396248754793,0.23726642403703146,0.8394016868466264,-0.4809780479553145,0.009638014956759703,3.351325980333631,-0.2904304927178063,0.03326476765043723,2.813285883739657,1.280324185022697,1.7330122185385242,-0.08691226787820137,0.36520852896444506,-0.4529950413267082,1.9009921408923331,0.9575234066599015,2.4176108705977826,0.23726642403703146,0.3443061993948582,-0.902417991440706,3.2657379732892013,1.7791593908234755,2.732890881137026,3.143317850644801,0.38594722827302785,-0.13645324700708894,2.6556741514333573,-0.2904304927178063,0.9243562959106226,0.40652433044515934,0.07992440556882748,1.5376396248754793,1.419454626258951,-0.3436274762646461,0.259018664523886,1.446271558144171,-0.5665281275626076,1.8465093473865353
| 3,193
|
Lipid transporter activity
| 7
| 16
| 2.710795
| 0.006712
|
P08183,Q14849,P61916,P17900,Q7Z3C6,P30536,Q96GC9
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
129,74,457,234,471,58,220
|
858,129,863,234,1847,515,58,888,1241,457,74,954,471,220,1429,1738
|
0.36520852896444506,2.0361169935164405,0.36520852896444506,1.446271558144171,-0.23818692761586824,0.7514043268649677,2.6556741514333573,0.3443061993948582,0.10296255264400622,0.8566305867164241,2.536807538431712,0.30200233977580343,0.8394016868466264,1.5248183397306079,0.009638014956759703,-0.16155054834083413
| 3,193
|
Cellular ion homeostasis
| 31
| 87
| 2.708346
| 0.006762
|
Q15043,Q93050,P02786,P51572,P09601,P78417,P50897,Q9HC07,Q9Y6M7,Q8IYU8,O95202,Q96A33,Q9BPX6,O75027,P16615,Q8N511,Q92544,P05067,Q9Y487,O76024,Q9UM00,Q9HD20,P42858,P61421,P62942,Q16611,Q15904,O75503,Q8TAD4,Q7L0J3,Q8WWC4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
256,138,265,141,17,145,19,146,151,410,155,284,297,170,300,49,315,438,71,454,214,87,341,466,481,355,230,104,105,108,502
|
1313,1274,2181,514,2264,801,170,104,1026,3153,454,155,2496,686,265,712,2449,438,1788,1134,726,2736,802,17,3092,2714,1752,2452,300,1944,864,580,1280,2892,3119,3087,1136,3043,2864,341,19,1287,141,3156,2615,2004,636,466,1623,481,145,994,1717,1328,2273,1043,256,2157,230,355,660,108,2831,410,49,876,105,502,315,138,284,819,1969,601,297,1383,1774,146,87,1696,1980,824,214,71,1019,2443,151
|
0.0566926794738131,0.07992440556882748,-0.4252722805882104,0.7514043268649677,-0.4809780479553145,0.40652433044515934,1.744645033106282,2.2812210779922095,0.23726642403703146,-2.0464349065431278,0.8566305867164241,1.8243030426289284,-0.6249367779380635,0.5267030007716262,1.3648314259575298,0.48725623745593405,-0.5955921179420027,0.8907287812193003,-0.21241421080737602,0.17094088359372295,0.46730587199900714,-0.8385853324054076,0.40652433044515934,3.250973747172662,-1.5417758052175927,-0.8071488815311059,-0.18686982059176915,-0.5955921179420027,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,0.07992440556882748,-1.034071137875609,-1.7020688805675812,-1.5028434769808663,0.17094088359372295,-1.3514355919674153,-1.00064563472387,1.1013384647454063,3.2108682288698214,0.07992440556882748,1.9223825076951602,-2.0464349065431278,-0.7146987125093559,-0.31690808027229783,0.5847653265563068,0.8394016868466264,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,-0.16155054834083413,0.0566926794738131,-0.4809780479553145,0.23726642403703146,1.392310058750564,-0.39780592754705757,1.4595591237186676,1.0543605595517835,0.5655565678430635,2.245500235348313,-0.934824649241834,0.9409967716069575,2.7869149799952893,0.36520852896444506,2.2812210779922095,0.7869794546562088,1.1776036696350574,1.9329933181047383,1.2946295225860096,0.40652433044515934,-0.2904304927178063,0.6415400506909451,1.2514414118114898,0.03326476765043723,-0.18686982059176915,1.9009921408923331,2.4176108705977826,-0.13645324700708894,-0.2904304927178063,0.40652433044515934,1.5376396248754793,2.582335824717171,0.259018664523886,-0.5665281275626076,1.8465093473865353
| 3,193
|
Organic acid transport
| 30
| 45
| 2.705198
| 0.006826
|
Q15758,P08183,P55011,P23786,P33527,P28288,Q6P4A7,P41440,O75915,O75746,Q9UJS0,Q9H2J7,Q96NB2,O43772,P53985,Q15042,Q9H2D1,Q9UBX3,P31751,P09455,P53007,Q9H9B4,O60831,P08195,Q02978,P11166,Q9Y619,Q9BQT8,Q7L0J3,O43808
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
899,129,636,4,888,515,142,654,528,527,428,289,677,162,169,814,47,54,313,567,730,879,478,727,870,863,239,238,108,505
|
2181,1571,162,505,478,527,528,1750,3084,1889,2351,2186,129,727,567,863,1710,4,515,313,1579,888,654,1853,730,169,636,3114,870,814,899,954,142,108,929,677,238,47,289,1599,879,54,428,2979,239
|
-0.4252722805882104,-0.08691226787820137,1.7905380137060627,0.7692555416447295,0.8220511190203319,0.7334243460639536,0.7334243460639536,-0.18686982059176915,-1.5028434769808663,-0.26419124276665046,-0.5377405503528547,-0.4252722805882104,2.0361169935164405,0.46730587199900714,0.6786968138424812,0.36520852896444506,-0.16155054834083413,3.6003046943759847,0.7514043268649677,1.1776036696350574,-0.08691226787820137,0.3443061993948582,0.5655565678430635,-0.23818692761586824,0.46730587199900714,1.7677180561785404,0.5847653265563068,-1.661294066844009,0.36520852896444506,0.40652433044515934,0.3443061993948582,0.30200233977580343,1.9117156067218775,2.245500235348313,0.32323817115644027,0.5462030417796385,1.446271558144171,2.813285883739657,1.280324185022697,-0.08691226787820137,0.36520852896444506,2.732890881137026,0.9243562959106226,-1.1713430341599453,1.446271558144171
| 3,193
|
Secondary active transmembrane transporter activity
| 11
| 22
| 2.693756
| 0.007065
|
Q15043,Q9H2J7,P53985,P05141,Q96ES6,P12235,Q9UBX3,Q9Y6M7,P12236,O95202,P51798
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
256,289,169,361,75,338,54,151,217,155,184
|
155,361,727,338,217,654,3156,184,730,169,636,1111,870,256,899,876,75,475,289,1599,54,151
|
1.8243030426289284,1.0384916258428032,0.46730587199900714,1.1013384647454063,1.5248183397306079,0.5655565678430635,-2.0464349065431278,1.6738619652882785,0.46730587199900714,1.7677180561785404,0.5847653265563068,0.19322985148629535,0.36520852896444506,1.392310058750564,0.3443061993948582,0.36520852896444506,2.5291039002629425,0.8394016868466264,1.280324185022697,-0.08691226787820137,2.732890881137026,1.8465093473865353
| 3,193
|
MFS transporter superfamily [IPR036259]
| 6
| 10
| 2.69108
| 0.007122
|
Q99808,P53985,Q96ES6,Q9H2V7,Q7L0J3,Q14728
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
321,169,75,174,108,305
|
863,654,169,305,342,1921,108,75,321,174
|
0.36520852896444506,0.5655565678430635,1.7677180561785404,1.207423100369303,1.1013384647454063,-0.26419124276665046,2.245500235348313,2.5291039002629425,1.1473959441543768,1.7330122185385242
| 3,193
|
Sphingolipid metabolism in senescence
| 6
| 12
| 2.682901
| 0.007299
|
Q06136,P16278,Q13510,O15269,P04062,Q96G23
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
99,11,116,303,122,159
|
303,122,1788,725,652,11,728,1136,409,99,116,159
|
1.207423100369303,2.153135324237049,-0.21241421080737602,0.46730587199900714,0.5655565678430635,3.418959561273887,0.46730587199900714,0.17094088359372295,0.9409967716069575,2.3075717767503545,2.1998773817605315,1.8243030426289284
| 3,193
|
Nucleotide transport
| 8
| 13
| 2.680606
| 0.007349
|
Q99808,Q8TB61,P05141,Q9H2D1,P12235,Q9HC21,Q9BSK2,P12236
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
321,101,361,47,338,405,212,217
|
505,361,338,217,654,835,1112,101,929,321,212,47,405
|
0.7692555416447295,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.5655565678430635,0.38594722827302785,0.19322985148629535,2.2988294808347165,0.32323817115644027,1.1473959441543768,1.5376396248754793,2.813285883739657,0.9575234066599015
| 3,193
|
primary active transporter
| 7
| 22
| 2.679037
| 0.007383
|
Q9H2J7,O75381,Q9BUN8,Q8N4H5,Q6P4A7,Q9NS69,Q15388
|
Functions
|
Panther Protein class
|
panther_protein_class
|
289,193,165,41,142,16,280
|
1167,193,1316,651,712,2449,2712,1614,300,580,2004,994,280,899,142,41,677,165,289,879,2253,16
|
0.1484683010782358,1.6375613175769943,0.0566926794738131,0.5655565678430635,0.48725623745593405,-0.5955921179420027,-0.8071488815311059,-0.11157482962869282,1.2368621349000533,0.6601866548649779,-0.31690808027229783,0.259018664523886,1.3088453672804772,0.3443061993948582,1.9117156067218775,2.8899600348937455,0.5462030417796385,1.7905380137060627,1.280324185022697,0.36520852896444506,-0.4529950413267082,3.2657379732892013
| 3,193
|
Ensheathment of neurons
| 12
| 26
| 2.656492
| 0.007896
|
Q92542,O15228,P53634,Q16880,Q7L576,Q15058,Q12959,P31751,O75746,P42345,Q9NR77,P18074
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
329,578,487,273,345,366,279,313,527,409,61,569
|
578,940,527,726,569,313,1502,409,608,487,279,1251,1955,366,1811,273,345,329,2959,1218,1380,61,2131,2080,1093,1019
|
0.6601866548649779,0.30200233977580343,0.7334243460639536,0.46730587199900714,0.6786968138424812,1.1776036696350574,-0.03822288271037234,0.9409967716069575,0.6227553904440447,0.8045775073895869,1.3088453672804772,0.10296255264400622,-0.2904304927178063,1.0225160037257737,-0.21241421080737602,1.3370121237135937,1.0857828718447309,1.1321439407679112,-1.1364774707508174,0.12580968009238108,0.03326476765043723,2.6412527563805264,-0.37059222129993374,-0.3436274762646461,0.21533758545793177,0.259018664523886
| 3,193
|
membrane traffic protein
| 22
| 63
| 2.645268
| 0.008163
|
Q9Y2T2,Q9UI14,P20645,Q9H223,Q8TAG9,A6NIH7,P43307,Q9UQ16,P51572,Q13432,Q96RL7,Q9NX40,Q00765,O60313,P78537,Q8N2H4,P11717,Q96FZ7,Q9H4M9,Q12907,O95782,Q96PC5
|
Functions
|
Panther Protein class
|
panther_protein_class
|
258,525,633,522,518,9,10,667,141,25,285,286,546,430,572,182,568,588,452,490,485,386
|
9,1313,1098,1440,1705,430,2137,1133,2764,485,568,633,1893,2455,973,1619,10,2503,867,777,141,2547,3059,2747,572,546,1910,1250,490,25,1172,926,182,518,1735,1966,1681,787,1344,1051,588,386,977,285,2168,666,522,822,847,452,1183,1057,3025,2731,286,2632,1264,2530,525,1484,667,986,258
|
3.4750650461264545,0.0566926794738131,0.19322985148629535,-0.014190283332690111,-0.16155054834083413,0.9076007240012801,-0.39780592754705757,0.17094088359372295,-0.8703399800828923,0.8045775073895869,0.6786968138424812,0.5847653265563068,-0.26419124276665046,-0.5955921179420027,0.28059656391052684,-0.11157482962869282,3.4750650461264545,-0.6249367779380635,0.36520852896444506,0.42694183408394704,1.9223825076951602,-0.6545664545020534,-1.3886547156284181,-0.8385853324054076,0.6786968138424812,0.7153141117668748,-0.26419124276665046,0.10296255264400622,0.8045775073895869,3.105660523374089,0.1484683010782358,0.32323817115644027,1.6858254775131012,0.7514043268649677,-0.16155054834083413,-0.2904304927178063,-0.13645324700708894,0.42694183408394704,0.0566926794738131,0.23726642403703146,0.6601866548649779,0.9902400838282385,0.28059656391052684,1.2946295225860096,-0.39780592754705757,0.5655565678430635,0.7514043268649677,0.40652433044515934,0.38594722827302785,0.8737391734444331,0.1484683010782358,0.23726642403703146,-1.2782188724392092,-0.8071488815311059,1.2946295225860096,-0.7146987125093559,0.10296255264400622,-0.6249367779380635,0.7514043268649677,-0.014190283332690111,0.5655565678430635,0.28059656391052684,1.392310058750564
| 3,193
|
Sterol biosynthetic process
| 11
| 24
| 2.6402
| 0.008286
|
O75845,P48449,Q15800,Q15125,P16435,Q9UBM7,Q14739,Q9UKR5,P04035,Q15392,Q16850
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
224,226,35,294,299,370,147,115,245,63,158
|
224,2311,1787,245,1709,2401,299,581,3000,226,1455,2746,2825,2913,403,147,294,2874,63,921,35,158,370,115
|
1.4858962903240147,-0.5092252179873332,-0.21241421080737602,1.419454626258951,-0.16155054834083413,-0.5665281275626076,1.2368621349000533,0.6601866548649779,-1.2422071670625843,1.4858962903240147,-0.014190283332690111,-0.8385853324054076,-0.934824649241834,-1.0678476456651755,0.9575234066599015,1.8684775279957868,1.2514414118114898,-1.00064563472387,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,1.0225160037257737,2.2182584184461103
| 3,193
|
Coated vesicle membrane
| 19
| 57
| 2.632095
| 0.008486
|
P24390,P20645,Q9NR31,P02786,Q14108,P61923,Q15363,Q9Y3B3,O43731,P49755,Q8N511,Q15437,P55735,P11717,P10321,Q9Y6Y8,Q13190,O95782,P04439
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,633,523,265,14,657,29,30,36,417,49,693,440,568,455,476,354,485,233
|
1313,1883,2635,798,1394,36,1705,2137,1355,1574,2764,2447,1194,942,485,1497,265,233,1990,455,2354,568,1945,633,2,990,1069,867,417,1360,2504,2267,1584,2321,440,657,2747,1625,354,14,1512,783,29,998,693,2328,49,1344,523,1224,1933,2978,2923,2028,30,710,476
|
0.0566926794738131,-0.26419124276665046,-0.7452104629394918,0.40652433044515934,0.009638014956759703,2.96913415144942,-0.16155054834083413,-0.39780592754705757,0.03326476765043723,-0.08691226787820137,-0.8703399800828923,-0.5955921179420027,0.12580968009238108,0.30200233977580343,0.8045775073895869,-0.03822288271037234,1.3648314259575298,1.446271558144171,-0.31690808027229783,0.8566305867164241,-0.5377405503528547,0.6786968138424812,-0.2904304927178063,0.5847653265563068,3.7462657069794476,0.259018664523886,0.21533758545793177,0.36520852896444506,0.9243562959106226,0.03326476765043723,-0.6249367779380635,-0.4809780479553145,-0.08691226787820137,-0.5092252179873332,0.8907287812193003,0.5655565678430635,-0.8385853324054076,-0.11157482962869282,1.0543605595517835,3.309160878702859,-0.03822288271037234,0.42694183408394704,3.078186020550252,0.259018664523886,0.5267030007716262,-0.5092252179873332,2.7869149799952893,0.0566926794738131,0.7514043268649677,0.12580968009238108,-0.26419124276665046,-1.1713430341599453,-1.0678476456651755,-0.31690808027229783,3.067058131253242,0.5070546681307051,0.8394016868466264
| 3,193
|
Abnormality of head blood vessel
| 7
| 21
| 2.630298
| 0.008531
|
P07602,P16278,P17900,Q13510,Q9Y4P3,P10619,Q9NZJ7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
72,11,234,116,253,127,191
|
1393,885,293,72,726,127,2228,11,234,542,2818,1285,2321,2506,116,1810,2328,2332,191,2339,253
|
0.009638014956759703,0.3443061993948582,1.2514414118114898,2.5672903217950718,0.46730587199900714,2.0857311239846426,-0.4529950413267082,3.418959561273887,1.446271558144171,0.7153141117668748,-0.934824649241834,0.07992440556882748,-0.5092252179873332,-0.6249367779380635,2.1998773817605315,-0.21241421080737602,-0.5092252179873332,-0.5092252179873332,1.6497305064842487,-0.5092252179873332,1.4059236947909328
| 3,193
|
Inner mitochondrial membrane organization
| 13
| 21
| 2.629126
| 0.00856
|
Q6UXV4,Q9P0J0,Q9Y512,Q9NVH1,Q9H3K2,Q9BUR5,Q16891,O60313,Q13505,Q8WWC4,P17152,O95202,Q5XKP0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
449,201,332,270,302,335,660,430,51,502,529,155,549
|
430,1610,1316,155,529,3155,51,660,1295,549,449,502,335,302,270,698,201,1019,332,1703,1272
|
0.9076007240012801,-0.11157482962869282,0.0566926794738131,1.8243030426289284,0.7334243460639536,-2.0464349065431278,2.746560633651398,0.5655565678430635,0.07992440556882748,0.7153141117668748,0.8737391734444331,0.7869794546562088,1.1167917984678513,1.2221896821440608,1.3509647782580774,0.5267030007716262,1.6006322940022837,0.259018664523886,1.1321439407679112,-0.13645324700708894,0.10296255264400622
| 3,193
|
Mitochondrial nucleotide transporter subfamily
| 7
| 9
| 2.624752
| 0.008671
|
P05141,Q9H2D1,P12235,Q70HW3,Q9HC21,Q9BSK2,P12236
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
361,47,338,50,405,212,217
|
505,361,338,217,1112,50,212,47,405
|
0.7692555416447295,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.19322985148629535,2.760120300435202,1.5376396248754793,2.813285883739657,0.9575234066599015
| 3,193
|
Copi dependent golgi to er retrograde traffic
| 21
| 52
| 2.620181
| 0.008788
|
P24390,O15260,P04350,Q9BVA1,P61923,P62820,Q15363,Q9Y3B3,O43731,P49755,Q12981,Q13509,Q9BVK6,Q9Y678,P68371,P84085,P52732,Q13885,Q9P2W9,Q8N6H7,Q9BUF5
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
2,259,390,404,657,531,29,30,36,417,420,691,444,710,320,458,596,612,100,500,378
|
1352,1233,2635,259,2304,36,1574,2312,1535,390,1169,2,972,990,2503,1069,417,596,2504,2267,2547,657,531,320,458,2152,1511,778,420,691,612,2325,29,737,500,1679,1215,1927,2780,2168,378,404,444,2170,1007,1928,961,100,1933,30,857,710
|
0.03326476765043723,0.10296255264400622,-0.7452104629394918,1.3786129091151909,-0.5092252179873332,2.96913415144942,-0.08691226787820137,-0.5092252179873332,-0.062462590653624604,0.9739374379111466,0.1484683010782358,3.7462657069794476,0.28059656391052684,0.259018664523886,-0.6249367779380635,0.21533758545793177,0.9243562959106226,0.6415400506909451,-0.6249367779380635,-0.4809780479553145,-0.6545664545020534,0.5655565678430635,0.7334243460639536,1.1473959441543768,0.8566305867164241,-0.39780592754705757,-0.03822288271037234,0.42694183408394704,0.9243562959106226,0.5267030007716262,0.6227553904440447,-0.5092252179873332,3.078186020550252,0.46730587199900714,0.7869794546562088,-0.13645324700708894,0.12580968009238108,-0.26419124276665046,-0.8703399800828923,-0.39780592754705757,1.006432544850282,0.9575234066599015,0.8907287812193003,-0.39780592754705757,0.259018664523886,-0.26419124276665046,0.30200233977580343,2.3075717767503545,-0.26419124276665046,3.067058131253242,0.38594722827302785,0.5070546681307051
| 3,193
|
Transport to the golgi and subsequent modification
| 33
| 85
| 2.617552
| 0.008856
|
P24390,Q14203,P04350,O60476,P04066,Q9BVA1,P61923,P62820,Q15363,Q9Y3B3,O43731,P49755,Q14789,Q13509,Q9BVK6,P55735,P68371,Q12893,P84085,Q9Y6Y8,O95249,Q13885,O15498,Q13190,Q12907,Q9UJW0,Q16706,P53634,Q8N6H7,O75935,Q9UBR2,Q9BUF5,Q96PC5
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
2,639,390,398,400,404,657,531,29,30,36,417,674,691,444,440,320,325,458,476,348,612,604,354,490,231,362,487,500,240,244,378,386
|
1532,2635,798,3157,1394,604,1101,1837,36,398,2137,1574,240,2447,348,1194,942,400,390,1169,2,990,2503,2865,1754,1069,867,417,2266,2504,2267,487,2321,2547,440,831,657,531,1624,320,833,458,1327,325,490,2551,354,812,691,813,1041,612,639,1913,674,29,998,362,1172,1116,500,1679,1214,1259,1215,1681,2759,1347,386,2168,378,404,444,961,1183,744,2295,1933,244,231,986,30,710,1162,476
|
-0.062462590653624604,-0.7452104629394918,0.40652433044515934,-2.1379443966160254,0.009638014956759703,0.6227553904440447,0.19322985148629535,-0.23818692761586824,2.96913415144942,0.9575234066599015,-0.39780592754705757,-0.08691226787820137,1.4329036514563958,-0.5955921179420027,1.070123936480939,0.12580968009238108,0.30200233977580343,0.9575234066599015,0.9739374379111466,0.1484683010782358,3.7462657069794476,0.259018664523886,-0.6249367779380635,-1.00064563472387,-0.18686982059176915,0.21533758545793177,0.36520852896444506,0.9243562959106226,-0.4809780479553145,-0.6249367779380635,-0.4809780479553145,0.8045775073895869,-0.5092252179873332,-0.6545664545020534,0.8907287812193003,0.38594722827302785,0.5655565678430635,0.7334243460639536,-0.11157482962869282,1.1473959441543768,0.38594722827302785,0.8566305867164241,0.0566926794738131,1.1321439407679112,0.8045775073895869,-0.6545664545020534,1.0543605595517835,0.40652433044515934,0.5267030007716262,0.40652433044515934,0.23726642403703146,0.6227553904440447,0.5847653265563068,-0.26419124276665046,0.5462030417796385,3.078186020550252,0.259018664523886,1.0384916258428032,0.1484683010782358,0.19322985148629535,0.7869794546562088,-0.13645324700708894,0.12580968009238108,0.10296255264400622,0.12580968009238108,-0.13645324700708894,-0.8385853324054076,0.0566926794738131,0.9902400838282385,-0.39780592754705757,1.006432544850282,0.9575234066599015,0.8907287812193003,0.30200233977580343,0.1484683010782358,0.46730587199900714,-0.4809780479553145,-0.26419124276665046,1.4329036514563958,1.4595591237186676,0.28059656391052684,3.067058131253242,0.5070546681307051,0.17094088359372295,0.8394016868466264
| 3,193
|
Macromolecule transmembrane transporter activity
| 6
| 11
| 2.613871
| 0.008952
|
O60830,Q99595,P49755,Q9NS69,O14925,Q15388
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,3,417,16,211,280
|
211,0,1316,651,417,1171,530,280,3,16,853
|
1.5376396248754793,4.042548479567164,0.0566926794738131,0.5655565678430635,0.9243562959106226,0.1484683010782358,0.7334243460639536,1.3088453672804772,3.6753208773984025,3.2657379732892013,0.38594722827302785
| 3,193
|
Copi mediated anterograde transport
| 24
| 60
| 2.613027
| 0.008974
|
P24390,Q14203,P04350,Q9BVA1,P61923,P62820,Q15363,Q9Y3B3,O43731,P49755,Q14789,Q13509,Q9BVK6,P68371,Q12893,P84085,O95249,Q13885,O15498,Q13190,Q9UJW0,Q8N6H7,O75935,Q9BUF5
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
2,639,390,404,657,531,29,30,36,417,674,691,444,320,325,458,348,612,604,354,231,500,240,378
|
2635,798,3157,604,1101,36,2137,240,348,390,1169,2,990,2503,2865,1754,1069,417,2266,2504,2267,2547,831,657,531,1624,320,833,458,1327,325,2551,354,812,691,813,1041,612,639,1913,674,29,500,1679,1214,1215,2759,1347,2168,378,404,444,961,1183,2295,1933,231,30,710,1162
|
-0.7452104629394918,0.40652433044515934,-2.1379443966160254,0.6227553904440447,0.19322985148629535,2.96913415144942,-0.39780592754705757,1.4329036514563958,1.070123936480939,0.9739374379111466,0.1484683010782358,3.7462657069794476,0.259018664523886,-0.6249367779380635,-1.00064563472387,-0.18686982059176915,0.21533758545793177,0.9243562959106226,-0.4809780479553145,-0.6249367779380635,-0.4809780479553145,-0.6545664545020534,0.38594722827302785,0.5655565678430635,0.7334243460639536,-0.11157482962869282,1.1473959441543768,0.38594722827302785,0.8566305867164241,0.0566926794738131,1.1321439407679112,-0.6545664545020534,1.0543605595517835,0.40652433044515934,0.5267030007716262,0.40652433044515934,0.23726642403703146,0.6227553904440447,0.5847653265563068,-0.26419124276665046,0.5462030417796385,3.078186020550252,0.7869794546562088,-0.13645324700708894,0.12580968009238108,0.12580968009238108,-0.8385853324054076,0.0566926794738131,-0.39780592754705757,1.006432544850282,0.9575234066599015,0.8907287812193003,0.30200233977580343,0.1484683010782358,-0.4809780479553145,-0.26419124276665046,1.4595591237186676,3.067058131253242,0.5070546681307051,0.17094088359372295
| 3,193
|
Corneal opacity
| 18
| 52
| 2.592052
| 0.009541
|
O75845,O75381,P51648,Q06136,P06280,P16278,P53701,Q9NVI7,P04066,O75844,O43505,Q9UBM7,Q13510,Q16625,Q9Y4P3,P04062,O95202,P10619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
224,193,130,99,298,11,456,369,400,81,275,370,116,342,253,122,155,127
|
2086,1393,463,275,1024,3040,1941,2981,193,81,224,2035,155,1168,1708,122,400,298,1943,127,11,1615,569,916,3113,2818,973,3120,130,596,456,1361,2409,2506,1906,99,690,2200,116,1810,1915,1858,342,1112,2917,369,719,370,2339,2218,253,1232
|
-0.37059222129993374,0.009638014956759703,0.8394016868466264,1.3229726085415559,0.23726642403703146,-1.3514355919674153,-0.2904304927178063,-1.2065841027857491,1.6375613175769943,2.4501778760429596,1.4858962903240147,-0.3436274762646461,1.8243030426289284,0.1484683010782358,-0.16155054834083413,2.153135324237049,0.9575234066599015,1.2368621349000533,-0.2904304927178063,2.0857311239846426,3.418959561273887,-0.11157482962869282,0.6786968138424812,0.32323817115644027,-1.661294066844009,-0.934824649241834,0.28059656391052684,-1.7020688805675812,2.015915696016737,0.6415400506909451,0.8566305867164241,0.03326476765043723,-0.5665281275626076,-0.6249367779380635,-0.26419124276665046,2.3075717767503545,0.5267030007716262,-0.4252722805882104,2.1998773817605315,-0.21241421080737602,-0.26419124276665046,-0.23818692761586824,1.1013384647454063,0.19322985148629535,-1.0678476456651755,1.0225160037257737,0.48725623745593405,1.0225160037257737,-0.5092252179873332,-0.4252722805882104,1.4059236947909328,0.12580968009238108
| 3,193
|
Cis golgi network
| 6
| 14
| 2.582769
| 0.009801
|
P24390,O43731,P49755,Q16706,O00461,O95249
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,36,417,362,28,348
|
28,1837,36,348,2,417,994,674,362,1048,1259,1215,2381,513
|
3.078186020550252,-0.23818692761586824,2.96913415144942,1.070123936480939,3.7462657069794476,0.9243562959106226,0.259018664523886,0.5462030417796385,1.0384916258428032,0.23726642403703146,0.10296255264400622,0.12580968009238108,-0.5377405503528547,0.7692555416447295
| 3,193
|
Dementia
| 25
| 58
| 2.581248
| 0.009844
|
Q14203,P04350,Q14108,Q06787,Q96RL7,O96008,Q96RR1,P06865,O60313,P05067,Q9NZJ7,Q9Y487,P07602,P61916,O76024,P42858,P00403,Q8WVX9,P21912,Q9UBB4,P17900,O43681,Q13510,P04062,Q9UHD9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
639,390,14,532,285,651,424,293,430,438,191,71,72,457,454,341,216,614,353,494,234,619,116,122,379
|
1098,858,2636,800,619,430,1193,454,651,216,122,2448,390,438,293,72,1842,2997,2891,234,2315,353,1033,1655,2610,1578,804,1617,2864,341,1505,2744,1141,1361,2969,457,1907,532,2871,116,14,639,1415,2205,1732,2373,614,2425,977,285,424,3098,1824,680,191,494,379,71
|
0.19322985148629535,0.36520852896444506,-0.7452104629394918,0.40652433044515934,0.6038310370230041,0.9076007240012801,0.12580968009238108,0.8566305867164241,0.5655565678430635,1.5248183397306079,2.153135324237049,-0.5955921179420027,0.9739374379111466,0.8907287812193003,1.2514414118114898,2.5672903217950718,-0.23818692761586824,-1.2422071670625843,-1.034071137875609,1.446271558144171,-0.5092252179873332,1.0543605595517835,0.23726642403703146,-0.13645324700708894,-0.7146987125093559,-0.08691226787820137,0.40652433044515934,-0.11157482962869282,-1.00064563472387,1.1013384647454063,-0.03822288271037234,-0.8385853324054076,0.17094088359372295,0.03326476765043723,-1.1713430341599453,0.8566305867164241,-0.26419124276665046,0.7334243460639536,-1.00064563472387,2.1998773817605315,3.309160878702859,0.5847653265563068,0.009638014956759703,-0.4252722805882104,-0.16155054834083413,-0.5377405503528547,0.6227553904440447,-0.5665281275626076,0.28059656391052684,1.2946295225860096,0.9243562959106226,-1.5417758052175927,-0.21241421080737602,0.5462030417796385,1.6497305064842487,0.8045775073895869,1.006432544850282,2.582335824717171
| 3,193
|
Exopeptidase activity
| 13
| 31
| 2.573946
| 0.010055
|
Q9H3G5,O14773,P02786,Q9HB40,Q92820,O75844,P42785,Q9UIQ6,Q9UBR2,P55786,Q9NZ08,O75976,P10619
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
38,264,265,42,364,81,18,213,244,218,287,437,127
|
264,81,437,265,1789,127,2715,2815,2358,1450,18,3095,487,218,3044,780,875,1552,364,1342,844,2564,38,1929,42,2215,2943,1776,287,244,213
|
1.3648314259575298,2.4501778760429596,0.8907287812193003,1.3648314259575298,-0.21241421080737602,2.0857311239846426,-0.8071488815311059,-0.934824649241834,-0.5377405503528547,-0.014190283332690111,3.226034750624375,-1.5417758052175927,0.8045775073895869,1.5248183397306079,-1.3514355919674153,0.42694183408394704,0.36520852896444506,-0.062462590653624604,1.0384916258428032,0.0566926794738131,0.38594722827302785,-0.6545664545020534,2.926986348323763,-0.26419124276665046,2.8899600348937455,-0.4252722805882104,-1.101981072569348,-0.18686982059176915,1.2946295225860096,1.4329036514563958,1.5376396248754793
| 3,193
|
mitochondria
| 6
| 11
| 2.572686
| 0.010091
|
Q8IWA4,P21796,Q9NVH1,P45880,Q9Y277,Q15388
|
Localization
|
OpenCell Localization
|
opencell_localization
|
328,7,270,15,247,280
|
1316,2735,7,15,2365,280,328,330,523,270,247
|
0.0566926794738131,-0.8385853324054076,3.5491802513502524,3.285196134499565,-0.5377405503528547,1.3088453672804772,1.1321439407679112,1.1321439407679112,0.7514043268649677,1.3509647782580774,1.419454626258951
| 3,193
|
Abnormal retinal artery morphology
| 7
| 18
| 2.570559
| 0.010153
|
P07602,P16278,P17900,Q13510,Q9Y4P3,P10619,Q9NZJ7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
72,11,234,116,253,127,191
|
885,293,72,726,127,2228,11,234,542,2818,2321,2506,116,1810,2332,191,2339,253
|
0.3443061993948582,1.2514414118114898,2.5672903217950718,0.46730587199900714,2.0857311239846426,-0.4529950413267082,3.418959561273887,1.446271558144171,0.7153141117668748,-0.934824649241834,-0.5092252179873332,-0.6249367779380635,2.1998773817605315,-0.21241421080737602,-0.5092252179873332,1.6497305064842487,-0.5092252179873332,1.4059236947909328
| 3,193
|
Abnormality of epiphysis morphology
| 17
| 56
| 2.567846
| 0.010233
|
O75381,O95831,Q7LGA3,Q96L58,Q96HA7,P10644,O00443,Q15125,Q9Y619,P16278,P16435,Q9HC07,Q14739,Q8WVQ1,O95202,P51798,P38435
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
193,194,131,291,319,225,350,294,239,11,299,146,147,311,155,184,255
|
1022,350,578,1396,2981,193,506,155,194,1168,225,11,299,2956,1501,1711,255,3155,973,184,1140,2409,2270,3034,1906,2197,778,2200,147,2325,294,921,2277,1172,737,2878,131,2830,956,842,311,2597,319,575,291,1426,1481,1183,146,2783,746,370,2218,1983,2029,239
|
0.23726642403703146,1.0543605595517835,0.6601866548649779,0.009638014956759703,-1.2065841027857491,1.6375613175769943,0.7692555416447295,1.8243030426289284,1.6375613175769943,0.1484683010782358,1.4858962903240147,3.418959561273887,1.2368621349000533,-1.1364774707508174,-0.03822288271037234,-0.16155054834083413,1.392310058750564,-2.0464349065431278,0.28059656391052684,1.6738619652882785,0.17094088359372295,-0.5665281275626076,-0.4809780479553145,-1.314626024117389,-0.26419124276665046,-0.4252722805882104,0.42694183408394704,-0.4252722805882104,1.8684775279957868,-0.5092252179873332,1.2514414118114898,0.32323817115644027,-0.4809780479553145,0.1484683010782358,0.46730587199900714,-1.00064563472387,1.985222235335816,-0.934824649241834,0.30200233977580343,0.38594722827302785,1.1925614229636166,-0.6844855875507391,1.162548846164761,0.6786968138424812,1.2659284528512882,0.009638014956759703,-0.014190283332690111,0.1484683010782358,1.9009921408923331,-0.8703399800828923,0.46730587199900714,1.0225160037257737,-0.4252722805882104,-0.2904304927178063,-0.31690808027229783,1.446271558144171
| 3,193
|
Subsets and Splits
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