term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Mitochondrial carrier protein [IPR002067]
7
11
2.551703
0.01072
Q9UJS0,P05141,Q9BQT8,P12235,Q9HC21,P12236,O43808
Sequence
InterPro Family
interpro_family
428,361,238,338,405,217,505
505,527,361,338,217,730,1112,238,1599,405,428
0.7692555416447295,0.7334243460639536,1.0384916258428032,1.1013384647454063,1.5248183397306079,0.46730587199900714,0.19322985148629535,1.446271558144171,-0.08691226787820137,0.9575234066599015,0.9243562959106226
3,193
Glycosphingolipid metabolic process
6
8
2.5504
0.01076
P06865,P06280,P16278,P17900,Q16880,P04062
Processes and pathways
GO Biological process
msigdb_gobp
293,298,11,234,273,122
122,298,293,726,11,234,273,367
2.153135324237049,1.2368621349000533,1.2514414118114898,0.46730587199900714,3.418959561273887,1.446271558144171,1.3370121237135937,1.0225160037257737
3,193
Rhizomelia
7
14
2.548125
0.01083
Q9BV10,Q15125,Q9UBM7,Q14739,Q03164,Q15392,Q96HA7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
199,294,370,147,60,63,319
1022,578,2981,1102,409,1069,60,147,294,63,1214,319,199,370
0.23726642403703146,0.6601866548649779,-1.2065841027857491,0.19322985148629535,0.9409967716069575,0.21533758545793177,2.648478537565285,1.8684775279957868,1.2514414118114898,2.6339966056994,0.12580968009238108,1.162548846164761,1.6130128562407051,1.0225160037257737
3,193
Inorganic ion transmembrane transport
40
111
2.545562
0.01091
Q15043,P21796,P27105,P13073,P78417,Q9HC07,Q06787,Q9UDW1,Q7KZN9,Q9Y6M7,Q12959,Q8IYU8,O95202,O75964,Q13423,Q9H2J7,Q9BPX6,P56385,P46934,O75027,P16615,P24539,Q9UBX3,Q9UHG3,P51798,P47985,Q96ES6,Q9BXP2,P12235,Q9UM00,Q9HD20,P42858,P00403,P61421,Q96GC9,P62942,Q8TAD4,P05141,Q8WWC4,Q6P4Q7
Processes and pathways
GO Biological process
msigdb_gobp
256,7,137,136,145,146,532,22,150,151,279,410,155,31,161,289,297,418,416,170,300,181,54,59,184,448,75,475,338,214,87,341,216,466,220,481,105,361,502,375
1234,2181,748,2264,170,1443,1493,2788,2671,31,155,1751,216,712,2449,361,2351,1134,1988,2736,727,752,1790,1709,338,136,300,1944,864,580,2092,1846,2639,2956,7,181,1997,137,3119,2894,3043,1795,1797,1617,2864,341,416,1661,448,3131,777,3156,184,2004,636,1199,418,466,530,1623,481,145,994,1111,1717,870,2463,532,2648,2551,279,161,2273,2691,2853,256,375,150,2831,410,2855,2777,876,105,502,1736,75,220,1969,3098,678,2381,297,1427,475,1973,1383,289,1599,146,87,904,54,22,1696,59,1980,824,214,1019,151
0.10296255264400622,-0.4252722805882104,0.44720170401297976,-0.4809780479553145,1.744645033106282,-0.014190283332690111,-0.03822288271037234,-0.902417991440706,-0.7760255732552376,3.0502155042807657,1.8243030426289284,-0.18686982059176915,1.5248183397306079,0.48725623745593405,-0.5955921179420027,1.0384916258428032,-0.5377405503528547,0.17094088359372295,-0.31690808027229783,-0.8385853324054076,0.46730587199900714,0.44720170401297976,-0.21241421080737602,-0.16155054834083413,1.1013384647454063,1.9329933181047383,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,-1.1364774707508174,3.5491802513502524,1.6858254775131012,-0.31690808027229783,1.9329933181047383,-1.7020688805675812,-1.034071137875609,-1.3514355919674153,-0.21241421080737602,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,1.1013384647454063,0.9243562959106226,-0.13645324700708894,0.8737391734444331,-1.7850748625508288,0.42694183408394704,-2.0464349065431278,1.6738619652882785,-0.31690808027229783,0.5847653265563068,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.7334243460639536,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,0.19322985148629535,-0.16155054834083413,0.36520852896444506,-0.5955921179420027,0.7334243460639536,-0.7452104629394918,-0.6545664545020534,1.3088453672804772,1.801854471157927,-0.4809780479553145,-0.7760255732552376,-0.9675653554604676,1.392310058750564,1.006432544850282,1.8465093473865353,-0.934824649241834,0.9409967716069575,-0.9675653554604676,-0.8703399800828923,0.36520852896444506,2.2812210779922095,0.7869794546562088,-0.16155054834083413,2.5291039002629425,1.5248183397306079,-0.2904304927178063,-1.5417758052175927,0.5462030417796385,-0.5377405503528547,1.2514414118114898,0.009638014956759703,0.8394016868466264,-0.2904304927178063,0.03326476765043723,1.280324185022697,-0.08691226787820137,1.9009921408923331,2.4176108705977826,0.3443061993948582,2.732890881137026,3.143317850644801,-0.13645324700708894,2.6556741514333573,-0.2904304927178063,0.40652433044515934,1.5376396248754793,0.259018664523886,1.8465093473865353
3,193
Outer mitochondrial membrane protein complex
12
16
2.545239
0.01092
Q6UXV4,Q8IWA4,Q8N4H5,Q9Y512,Q9NVH1,Q9NS69,Q9BUR5,Q16891,Q13505,Q15388,O96008,Q5XKP0
Localization
GO Cellular component
msigdb_gocc
449,328,41,332,270,16,335,660,51,280,651,549
1610,1316,651,3155,51,280,660,549,449,328,41,335,16,270,698,332
-0.11157482962869282,0.0566926794738131,0.5655565678430635,-2.0464349065431278,2.746560633651398,1.3088453672804772,0.5655565678430635,0.7153141117668748,0.8737391734444331,1.1321439407679112,2.8899600348937455,1.1167917984678513,3.2657379732892013,1.3509647782580774,0.5267030007716262,1.1321439407679112
3,193
Protein transmembrane transporter activity
6
10
2.544999
0.010928
O60830,Q99595,P49755,Q9NS69,O14925,Q15388
Functions
GO Molecular function
msigdb_gomf
0,3,417,16,211,280
211,0,1316,651,417,530,280,3,16,853
1.5376396248754793,4.042548479567164,0.0566926794738131,0.5655565678430635,0.9243562959106226,0.7334243460639536,1.3088453672804772,3.6753208773984025,3.2657379732892013,0.38594722827302785
3,193
Sterol metabolism
11
26
2.544661
0.010938
P35610,O75845,Q15800,Q15125,Q9UBM7,Q14739,Q9UKR5,P04035,Q15392,P04062,Q16850
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
288,224,35,294,370,147,115,245,63,122,158
858,224,2311,1787,245,122,2401,2607,288,581,2746,457,1952,2825,2913,147,294,2874,63,921,35,158,2328,370,1695,115
0.36520852896444506,1.4858962903240147,-0.5092252179873332,-0.21241421080737602,1.419454626258951,2.153135324237049,-0.5665281275626076,-0.7146987125093559,1.280324185022697,0.6601866548649779,-0.8385853324054076,0.8566305867164241,-0.2904304927178063,-0.934824649241834,-1.0678476456651755,1.8684775279957868,1.2514414118114898,-1.00064563472387,2.6339966056994,0.32323817115644027,2.975065555239934,1.8243030426289284,-0.5092252179873332,1.0225160037257737,-0.13645324700708894,2.2182584184461103
3,193
Abnormal biliary tract morphology
9
23
2.537219
0.011174
Q9Y5L0,Q9UJW0,P07602,Q14108,P09601,Q14739,Q10713,P04062,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
397,231,72,14,17,147,497,122,191
619,1708,122,72,17,1710,2891,3100,1711,2685,1324,1141,497,14,147,549,1967,1925,1223,191,231,1230,397
0.6038310370230041,-0.16155054834083413,2.153135324237049,2.5672903217950718,3.250973747172662,-0.16155054834083413,-1.034071137875609,-1.581156126510372,-0.16155054834083413,-0.7760255732552376,0.0566926794738131,0.17094088359372295,0.7869794546562088,3.309160878702859,1.8684775279957868,0.7153141117668748,-0.2904304927178063,-0.26419124276665046,0.12580968009238108,1.6497305064842487,1.4595591237186676,0.12580968009238108,0.9739374379111466
3,193
Avascular necrosis
7
23
2.534565
0.011259
Q9Y619,Q14108,O75844,Q9BUR4,P04062,Q9NZ08,P51798
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
239,14,81,188,122,287,184
2086,2033,81,2035,1786,1497,1708,122,2400,622,1401,184,2197,14,2878,1145,319,188,1481,746,3122,287,239
-0.37059222129993374,-0.3436274762646461,2.4501778760429596,-0.3436274762646461,-0.21241421080737602,-0.03822288271037234,-0.16155054834083413,2.153135324237049,-0.5665281275626076,0.6038310370230041,0.009638014956759703,1.6738619652882785,-0.4252722805882104,3.309160878702859,-1.00064563472387,0.17094088359372295,1.162548846164761,1.6738619652882785,-0.014190283332690111,0.46730587199900714,-1.7020688805675812,1.2946295225860096,1.446271558144171
3,193
Golgi cisterna
12
21
2.532336
0.011331
Q9H4A6,Q96L58,Q12893,Q10471,Q16706,P51572,O95249,P04439,Q8WVQ1,Q9Y3A3,O00461,Q15363
Localization
GO Cellular component
msigdb_gocc
426,291,325,489,362,141,348,233,311,252,28,29
28,1099,348,233,3092,141,994,2748,489,497,325,2157,29,362,1048,1259,311,291,426,3137,252
3.078186020550252,0.19322985148629535,1.070123936480939,1.446271558144171,-1.5417758052175927,1.9223825076951602,0.259018664523886,-0.8385853324054076,0.8045775073895869,0.7869794546562088,1.1321439407679112,-0.39780592754705757,3.078186020550252,1.0384916258428032,0.23726642403703146,0.10296255264400622,1.1925614229636166,1.2659284528512882,0.9243562959106226,-1.8273246014917721,1.4059236947909328
3,193
Divalent inorganic cation homeostasis
20
54
2.530126
0.011402
Q15043,Q8NE01,P51572,P78417,Q9HC07,Q8IYU8,O95202,Q96A33,Q9BPX6,P16615,P05067,O76024,Q9UM00,Q9HD20,P42858,P62942,Q16611,Q8TAD4,Q7L0J3,Q6P4Q7
Processes and pathways
GO Biological process
msigdb_gobp
256,128,141,145,146,410,155,284,297,300,438,454,214,87,341,481,355,105,108,375
1313,1274,1191,2264,454,155,2496,2449,438,1788,726,2736,802,1752,2452,300,1944,864,580,3119,3087,3043,341,141,2615,1623,481,145,994,1717,2551,2273,1043,256,2157,355,660,375,108,2831,410,128,876,105,502,284,1969,601,297,146,87,824,214,1019
0.0566926794738131,0.07992440556882748,0.12580968009238108,-0.4809780479553145,0.8566305867164241,1.8243030426289284,-0.6249367779380635,-0.5955921179420027,0.8907287812193003,-0.21241421080737602,0.46730587199900714,-0.8385853324054076,0.40652433044515934,-0.18686982059176915,-0.5955921179420027,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,-1.7020688805675812,-1.5028434769808663,-1.3514355919674153,1.1013384647454063,1.9223825076951602,-0.7146987125093559,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,-0.16155054834083413,-0.6545664545020534,-0.4809780479553145,0.23726642403703146,1.392310058750564,-0.39780592754705757,1.0543605595517835,0.5655565678430635,1.006432544850282,2.245500235348313,-0.934824649241834,0.9409967716069575,2.075908277865556,0.36520852896444506,2.2812210779922095,0.7869794546562088,1.2946295225860096,-0.2904304927178063,0.6415400506909451,1.2514414118114898,1.9009921408923331,2.4176108705977826,0.40652433044515934,1.5376396248754793,0.259018664523886
3,193
Retrograde transport endosome to golgi
11
32
2.5182
0.011796
O15498,Q13190,O15260,O60499,O75503,Q4J6C6,Q9BVK6,Q9Y5X3,P53367,O95249,Q9UID3
Processes and pathways
GO Biological process
msigdb_gobp
604,354,259,103,104,235,444,648,248,348,615
259,604,1164,2222,103,1132,1133,104,348,1897,867,1287,248,1625,354,1548,639,235,1413,926,817,1215,1866,977,444,1056,1565,1264,2178,615,984,648
1.3786129091151909,0.6227553904440447,0.1484683010782358,-0.4529950413267082,2.2812210779922095,0.17094088359372295,0.17094088359372295,2.2812210779922095,1.070123936480939,-0.26419124276665046,0.36520852896444506,0.07992440556882748,1.4059236947909328,-0.11157482962869282,1.0543605595517835,-0.062462590653624604,0.5847653265563068,1.446271558144171,0.009638014956759703,0.32323817115644027,0.40652433044515934,0.12580968009238108,-0.23818692761586824,0.28059656391052684,0.8907287812193003,0.23726642403703146,-0.062462590653624604,0.10296255264400622,-0.39780592754705757,0.6227553904440447,0.28059656391052684,0.5847653265563068
3,193
Snare interactions in vesicular transport
8
15
2.51582
0.011876
O15498,Q13190,Q9P2W9,Q12981,O60499,O15400,O95721,O95249
Processes and pathways
KEGG Pathways
msigdb_kegg
604,354,100,420,103,413,399,348
2345,798,413,604,103,1574,348,399,1360,1407,420,354,627,100,855
-0.5377405503528547,0.40652433044515934,0.9243562959106226,0.6227553904440447,2.2812210779922095,-0.08691226787820137,1.070123936480939,0.9575234066599015,0.03326476765043723,0.009638014956759703,0.9243562959106226,1.0543605595517835,0.6038310370230041,2.3075717767503545,0.38594722827302785
3,193
Snap receptor activity
8
15
2.51582
0.011876
O15498,Q13190,Q9P2W9,Q12981,O60499,O15400,O95721,O95249
Functions
GO Molecular function
msigdb_gomf
604,354,100,420,103,413,399,348
2345,798,413,604,103,1574,348,399,1360,1407,420,354,627,100,855
-0.5377405503528547,0.40652433044515934,0.9243562959106226,0.6227553904440447,2.2812210779922095,-0.08691226787820137,1.070123936480939,0.9575234066599015,0.03326476765043723,0.009638014956759703,0.9243562959106226,1.0543605595517835,0.6038310370230041,2.3075717767503545,0.38594722827302785
3,193
Regulation of cellular ph
8
22
2.515107
0.0119
Q15904,Q9Y487,Q93050,O75503,Q8N511,Q9HC07,P50897,Q9Y6M7
Processes and pathways
GO Biological process
msigdb_gobp
230,71,138,104,49,146,19,151
104,686,1134,3092,2892,1136,19,1287,3156,466,1328,230,49,315,138,819,146,1696,1980,71,2443,151
2.2812210779922095,0.5267030007716262,0.17094088359372295,-1.5417758052175927,-1.034071137875609,0.17094088359372295,3.2108682288698214,0.07992440556882748,-2.0464349065431278,0.8394016868466264,0.0566926794738131,1.4595591237186676,2.7869149799952893,1.1776036696350574,1.9329933181047383,0.40652433044515934,1.9009921408923331,-0.13645324700708894,-0.2904304927178063,2.582335824717171,-0.5665281275626076,1.8465093473865353
3,193
Regulation of ph
8
22
2.515107
0.0119
Q15904,Q9Y487,Q93050,O75503,Q8N511,Q9HC07,P50897,Q9Y6M7
Processes and pathways
GO Biological process
msigdb_gobp
230,71,138,104,49,146,19,151
104,686,1134,3092,2892,1136,19,1287,3156,466,1328,230,49,315,138,819,146,1696,1980,71,2443,151
2.2812210779922095,0.5267030007716262,0.17094088359372295,-1.5417758052175927,-1.034071137875609,0.17094088359372295,3.2108682288698214,0.07992440556882748,-2.0464349065431278,0.8394016868466264,0.0566926794738131,1.4595591237186676,2.7869149799952893,1.1776036696350574,1.9329933181047383,0.40652433044515934,1.9009921408923331,-0.13645324700708894,-0.2904304927178063,2.582335824717171,-0.5665281275626076,1.8465093473865353
3,193
Protein transmembrane transport
13
24
2.514419
0.011923
O60830,Q15629,O75381,Q99595,O95831,P49755,O43615,Q9NS69,O14925,P61619,Q15388,P31751,Q99442
Processes and pathways
GO Biological process
msigdb_gobp
0,64,193,3,194,417,414,16,211,530,280,313,359
211,414,0,193,1316,194,651,3129,669,313,417,3059,2270,530,280,64,557,3007,2832,359,3,2253,16,853
1.5376396248754793,0.9243562959106226,4.042548479567164,1.6375613175769943,0.0566926794738131,1.6375613175769943,0.5655565678430635,-1.7850748625508288,0.5462030417796385,1.1776036696350574,0.9243562959106226,-1.3886547156284181,-0.4809780479553145,0.7334243460639536,1.3088453672804772,2.62670988147732,0.6970721128067479,-1.2422071670625843,-0.934824649241834,1.0543605595517835,3.6753208773984025,-0.4529950413267082,3.2657379732892013,0.38594722827302785
3,193
Synaptic vesicle membrane
9
16
2.513373
0.011958
O60499,O76024,P20020,Q86Y82,Q15907,Q7L0J3,O43760,O95295,O15126
Localization
GO Cellular component
msigdb_gocc
103,454,580,627,306,108,125,686,436
1098,436,125,103,454,686,1990,580,1945,1287,1666,783,306,108,627,1378
0.19322985148629535,0.8907287812193003,2.09550477869399,2.2812210779922095,0.8566305867164241,0.5267030007716262,-0.31690808027229783,0.6601866548649779,-0.2904304927178063,0.07992440556882748,-0.13645324700708894,0.42694183408394704,1.207423100369303,2.245500235348313,0.6038310370230041,0.03326476765043723
3,193
Dermal atrophy
10
25
2.495532
0.012577
P10644,Q96L58,P53701,P53634,Q9H1A4,O75844,Q8NCH0,Q9NWM8,P18074,Q15392
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
225,291,456,487,504,81,82,406,569,63
2085,2033,81,1786,1708,2140,225,569,916,1105,622,2504,487,456,1667,1367,1811,2157,63,82,291,2431,504,406,719
-0.37059222129993374,-0.3436274762646461,2.4501778760429596,-0.21241421080737602,-0.16155054834083413,-0.39780592754705757,1.4858962903240147,0.6786968138424812,0.32323817115644027,0.19322985148629535,0.6038310370230041,-0.6249367779380635,0.8045775073895869,0.8566305867164241,-0.13645324700708894,0.03326476765043723,-0.21241421080737602,-0.39780592754705757,2.6339966056994,2.4420909128633217,1.2659284528512882,-0.5665281275626076,0.7869794546562088,0.9575234066599015,0.48725623745593405
3,193
Disproportionate short limb short stature
11
24
2.488149
0.012841
P10644,Q7LGA3,Q15125,Q9BV10,Q9UBM7,Q14739,Q8WVQ1,P42345,Q03164,Q15392,Q96HA7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
225,131,294,199,370,147,311,409,60,63,319
1022,578,2981,1102,225,2932,409,1069,60,3163,1631,147,294,63,432,1082,131,842,1214,311,2597,319,199,370
0.23726642403703146,0.6601866548649779,-1.2065841027857491,0.19322985148629535,1.4858962903240147,-1.101981072569348,0.9409967716069575,0.21533758545793177,2.648478537565285,-2.1845722045277824,-0.11157482962869282,1.8684775279957868,1.2514414118114898,2.6339966056994,0.9076007240012801,0.21533758545793177,1.985222235335816,0.38594722827302785,0.12580968009238108,1.1925614229636166,-0.6844855875507391,1.162548846164761,1.6130128562407051,1.0225160037257737
3,193
Regulation of autophagy
22
89
2.484104
0.012988
Q9NZ45,P21796,Q93050,P09601,P42345,O00165,O15269,P30536,Q9NZJ7,Q9Y487,P07602,O75844,P12235,P42858,Q86UE4,Q96DM3,O00443,P05141,P04062,Q9UHD9,P19474,P10619
Processes and pathways
GO Biological process
msigdb_gobp
134,7,138,17,409,45,303,58,191,71,72,81,338,341,92,357,350,361,122,379,254,127
45,1188,1098,350,1490,858,303,1060,2087,800,1574,1133,81,1317,2907,122,2576,2140,1651,361,826,72,1840,2352,802,17,127,338,254,1399,1846,2639,7,2892,58,1617,2864,1898,409,2742,341,416,2867,1901,466,2824,2049,1290,1717,1907,2869,610,760,2364,838,2588,814,548,1373,92,1418,2373,2698,665,1259,138,787,357,2562,977,3098,1523,577,3010,791,1185,2174,134,191,1781,2178,379,1980,984,1094,512,71,648,1232
2.832792341598909,0.12580968009238108,0.19322985148629535,1.0543605595517835,-0.03822288271037234,0.36520852896444506,1.207423100369303,0.21533758545793177,-0.37059222129993374,0.40652433044515934,-0.08691226787820137,0.17094088359372295,2.4501778760429596,0.0566926794738131,-1.0678476456651755,2.153135324237049,-0.6844855875507391,-0.39780592754705757,-0.13645324700708894,1.0384916258428032,0.38594722827302785,2.5672903217950718,-0.23818692761586824,-0.5377405503528547,0.40652433044515934,3.250973747172662,2.0857311239846426,1.1013384647454063,1.392310058750564,0.009638014956759703,-0.23818692761586824,-0.7452104629394918,3.5491802513502524,-1.034071137875609,2.6556741514333573,-0.11157482962869282,-1.00064563472387,-0.26419124276665046,0.9409967716069575,-0.8385853324054076,1.1013384647454063,0.9243562959106226,-1.00064563472387,-0.26419124276665046,0.8394016868466264,-0.934824649241834,-0.3436274762646461,0.07992440556882748,-0.16155054834083413,-0.26419124276665046,-1.00064563472387,0.6227553904440447,0.44720170401297976,-0.5377405503528547,0.38594722827302785,-0.6844855875507391,0.40652433044515934,0.7153141117668748,0.03326476765043723,2.359178009634381,0.009638014956759703,-0.5377405503528547,-0.7760255732552376,0.5655565678430635,0.10296255264400622,1.9329933181047383,0.42694183408394704,1.0543605595517835,-0.6545664545020534,0.28059656391052684,-1.5417758052175927,-0.03822288271037234,0.6786968138424812,-1.2422071670625843,0.42694183408394704,0.1484683010782358,-0.39780592754705757,1.9748849511122126,1.6497305064842487,-0.18686982059176915,-0.39780592754705757,1.006432544850282,-0.2904304927178063,0.28059656391052684,0.21533758545793177,0.7692555416447295,2.582335824717171,0.5847653265563068,0.12580968009238108
3,193
Intrinsic component of golgi membrane
6
9
2.482793
0.013036
Q8TB61,O15258,Q6ZRP7,O43505,Q9Y282,Q8N2H4
Localization
GO Cellular component
msigdb_gocc
101,351,295,275,85,182
912,351,275,994,489,295,182,101,85
0.32323817115644027,1.0543605595517835,1.3229726085415559,0.259018664523886,0.8045775073895869,1.2514414118114898,1.6858254775131012,2.2988294808347165,2.4339675988258307
3,193
Intrinsic component of plasma membrane
40
76
2.482683
0.01304
Q15043,P55011,P20645,P02786,P27105,P51572,O60637,P17152,Q99797,Q9UJS0,O96005,Q9H2J7,P53985,Q8WTV0,P16615,Q9Y4G8,O43657,P11279,P05067,P35613,P11717,Q99808,Q92542,P10321,Q8N2K0,P20020,P12235,Q9UIQ6,Q13641,O15111,O15498,Q12907,P05141,Q8TAD4,P04439,Q99805,O00264,A0FGR8,O95864,Q9BTU6
Localization
GO Cellular component
msigdb_gocc
256,636,633,265,137,141,20,529,411,428,160,289,169,43,300,180,53,309,438,317,568,321,329,455,203,580,338,213,468,463,604,490,361,105,233,367,371,617,374,641
617,371,1236,463,858,604,800,53,20,374,160,1497,265,233,712,2449,438,361,2351,455,863,309,568,338,300,529,1576,580,633,137,865,888,1796,317,1450,654,141,3156,169,2004,636,731,1111,870,835,490,950,468,2853,256,2157,839,899,1338,203,1174,1175,105,929,43,329,411,367,321,2381,641,3192,1973,289,2389,848,2174,213,428,855,180
0.6038310370230041,1.006432544850282,0.10296255264400622,0.8394016868466264,0.36520852896444506,0.6227553904440447,0.40652433044515934,2.732890881137026,3.205778316696798,1.006432544850282,1.8131093029975978,-0.03822288271037234,1.3648314259575298,1.446271558144171,0.48725623745593405,-0.5955921179420027,0.8907287812193003,1.0384916258428032,-0.5377405503528547,0.8566305867164241,0.36520852896444506,1.1925614229636166,0.6786968138424812,1.1013384647454063,1.2368621349000533,0.7334243460639536,-0.08691226787820137,0.6601866548649779,0.5847653265563068,1.9329933181047383,0.36520852896444506,0.3443061993948582,-0.21241421080737602,1.162548846164761,-0.014190283332690111,0.5655565678430635,1.9223825076951602,-2.0464349065431278,1.7677180561785404,-0.31690808027229783,0.5847653265563068,0.46730587199900714,0.19322985148629535,0.36520852896444506,0.38594722827302785,0.8045775073895869,0.30200233977580343,0.8394016868466264,-0.9675653554604676,1.392310058750564,-0.39780592754705757,0.38594722827302785,0.3443061993948582,0.0566926794738131,1.575655220295083,0.1484683010782358,0.1484683010782358,2.2812210779922095,0.32323817115644027,2.871125247428219,1.1321439407679112,0.9409967716069575,1.0225160037257737,1.1473959441543768,-0.5377405503528547,0.5847653265563068,-14.388945867155861,-0.2904304927178063,1.280324185022697,-0.5377405503528547,0.38594722827302785,-0.39780592754705757,1.5376396248754793,0.9243562959106226,0.38594722827302785,1.6977216604154457
3,193
Mental deterioration
40
96
2.478872
0.01318
Q9BQE5,Q14203,P16278,P04350,O43819,Q14108,P50897,Q06787,Q96RL7,O96008,Q5XKP0,Q96RR1,P21964,P54802,P06865,O95470,O60313,P18074,Q03164,P05067,Q9NZJ7,Q9NPL8,Q9Y487,P07602,P61916,O76024,O75306,P42858,P00403,Q8WVX9,P10644,P21912,Q9UBB4,O75503,P17900,O43681,Q13510,Q10713,P04062,Q9UHD9
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
6,639,11,390,514,14,19,532,285,651,549,424,542,166,293,171,430,569,60,438,191,591,71,72,457,454,205,341,216,614,225,353,494,104,234,619,116,497,122,379
1098,858,2636,800,619,514,430,2182,1193,205,104,454,2735,171,651,216,122,2448,390,438,293,72,726,886,2791,1842,2997,225,2891,11,2091,234,569,2315,353,542,1033,1655,2610,1578,804,1617,2864,1451,341,1505,2643,19,2911,2744,1141,166,1361,2969,457,2410,1625,60,1907,2869,532,2775,497,1292,2871,116,14,639,2650,1415,549,2517,2246,2205,1732,2373,614,2425,878,977,285,424,3098,1824,3008,6,2169,591,680,2568,191,494,1978,379,2762,71
0.19322985148629535,0.36520852896444506,-0.7452104629394918,0.40652433044515934,0.6038310370230041,0.7514043268649677,0.9076007240012801,-0.4252722805882104,0.12580968009238108,1.5503857345605445,2.2812210779922095,0.8566305867164241,-0.8385853324054076,1.744645033106282,0.5655565678430635,1.5248183397306079,2.153135324237049,-0.5955921179420027,0.9739374379111466,0.8907287812193003,1.2514414118114898,2.5672903217950718,0.46730587199900714,0.3443061993948582,-0.902417991440706,-0.23818692761586824,-1.2422071670625843,1.4858962903240147,-1.034071137875609,3.418959561273887,-0.37059222129993374,1.446271558144171,0.6786968138424812,-0.5092252179873332,1.0543605595517835,0.7153141117668748,0.23726642403703146,-0.13645324700708894,-0.7146987125093559,-0.08691226787820137,0.40652433044515934,-0.11157482962869282,-1.00064563472387,-0.014190283332690111,1.1013384647454063,-0.03822288271037234,-0.7452104629394918,3.2108682288698214,-1.0678476456651755,-0.8385853324054076,0.17094088359372295,1.7791593908234755,0.03326476765043723,-1.1713430341599453,0.8566305867164241,-0.5665281275626076,-0.11157482962869282,2.648478537565285,-0.26419124276665046,-1.00064563472387,0.7334243460639536,-0.8703399800828923,0.7869794546562088,0.07992440556882748,-1.00064563472387,2.1998773817605315,3.309160878702859,0.5847653265563068,-0.7452104629394918,0.009638014956759703,0.7153141117668748,-0.6249367779380635,-0.4529950413267082,-0.4252722805882104,-0.16155054834083413,-0.5377405503528547,0.6227553904440447,-0.5665281275626076,0.36520852896444506,0.28059656391052684,1.2946295225860096,0.9243562959106226,-1.5417758052175927,-0.21241421080737602,-1.2422071670625843,3.5925647235517952,-0.39780592754705757,0.6601866548649779,0.5462030417796385,-0.6545664545020534,1.6497305064842487,0.8045775073895869,-0.2904304927178063,1.006432544850282,-0.8385853324054076,2.582335824717171
3,193
Glycosylation
17
44
2.476316
0.013275
Q96L58,Q2TAA5,Q6ZXV5,Q9BV10,Q13724,O75503,Q10471,Q16706,O60476,Q86YN1,O43505,Q9HC07,O60502,Q9Y5P6,P46977,P04062,Q9BT22
Processes and pathways
GO Biological process
msigdb_gobp
291,326,559,199,517,104,489,362,398,177,275,146,52,445,206,122,316
2605,858,2394,3012,275,398,52,1396,1166,1355,104,2089,122,687,1030,1896,206,713,833,1667,1909,489,517,872,362,326,559,1765,177,587,1214,291,1347,316,199,1973,1222,1183,146,2783,1483,1696,445,3160
-0.7146987125093559,0.36520852896444506,-0.5665281275626076,-1.2782188724392092,1.3229726085415559,0.9575234066599015,2.7397396070190534,0.009638014956759703,0.1484683010782358,0.03326476765043723,2.2812210779922095,-0.37059222129993374,2.153135324237049,0.5267030007716262,0.23726642403703146,-0.26419124276665046,1.5503857345605445,0.48725623745593405,0.38594722827302785,-0.13645324700708894,-0.26419124276665046,0.8045775073895869,0.7514043268649677,0.36520852896444506,1.0384916258428032,1.1321439407679112,0.6970721128067479,-0.18686982059176915,1.7095511162040427,0.6601866548649779,0.12580968009238108,1.2659284528512882,0.0566926794738131,1.1776036696350574,1.6130128562407051,-0.2904304927178063,0.12580968009238108,0.1484683010782358,1.9009921408923331,-0.8703399800828923,-0.014190283332690111,-0.13645324700708894,0.8907287812193003,-2.1379443966160254
3,193
Delusions
10
21
2.475319
0.013312
P49770,P21964,Q9BQE5,P04062,P07602,P42858,Q96RL7,Q9NR50,Q9UJS0,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
608,542,6,122,72,341,285,349,428,191
2086,619,122,72,886,2891,542,2044,1450,341,608,2614,1251,2154,1302,285,6,349,191,2131,428
-0.37059222129993374,0.6038310370230041,2.153135324237049,2.5672903217950718,0.3443061993948582,-1.034071137875609,0.7153141117668748,-0.3436274762646461,-0.014190283332690111,1.1013384647454063,0.6227553904440447,-0.7146987125093559,0.10296255264400622,-0.39780592754705757,0.07992440556882748,1.2946295225860096,3.5925647235517952,1.070123936480939,1.6497305064842487,-0.37059222129993374,0.9243562959106226
3,193
Cellular transition metal ion homeostasis
10
21
2.473643
0.013374
Q15043,Q15904,Q9Y487,P02786,O75027,Q8TAD4,P09601,Q8N511,P61421,P05067
Processes and pathways
GO Biological process
msigdb_gobp
256,230,71,265,170,105,17,49,466,438
1313,1274,514,801,170,1026,3153,265,438,17,1280,3043,2864,466,256,230,49,105,1383,1774,71
0.0566926794738131,0.07992440556882748,0.7514043268649677,0.40652433044515934,1.744645033106282,0.23726642403703146,-2.0464349065431278,1.3648314259575298,0.8907287812193003,3.250973747172662,0.07992440556882748,-1.3514355919674153,-1.00064563472387,0.8394016868466264,1.392310058750564,1.4595591237186676,2.7869149799952893,2.2812210779922095,0.03326476765043723,-0.18686982059176915,2.582335824717171
3,193
Abnormality of corneal stroma
6
13
2.472527
0.013416
O75845,P16278,O43505,Q13510,P04062,P10619
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
224,11,275,116,122,127
275,224,122,127,11,1615,569,916,3113,1361,116,342,2218
1.3229726085415559,1.4858962903240147,2.153135324237049,2.0857311239846426,3.418959561273887,-0.11157482962869282,0.6786968138424812,0.32323817115644027,-1.661294066844009,0.03326476765043723,2.1998773817605315,1.1013384647454063,-0.4252722805882104
3,193
Calcium signaling pathway
8
17
2.470172
0.013505
P21796,P05141,P16615,P46020,P45880,P12235,Q9Y277,P12236
Processes and pathways
KEGG Pathways
msigdb_kegg
7,361,300,486,15,338,247,217
361,1788,338,217,300,1944,864,580,7,15,486,2775,2103,1668,2273,1696,247
1.0384916258428032,-0.21241421080737602,1.1013384647454063,1.5248183397306079,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,3.5491802513502524,3.285196134499565,0.8045775073895869,-0.8703399800828923,-0.37059222129993374,-0.13645324700708894,-0.4809780479553145,-0.13645324700708894,1.419454626258951
3,193
Cation transmembrane transport
43
118
2.469374
0.013535
Q15043,P21796,P27105,P13073,P78417,Q9HC07,Q06787,Q9UDW1,Q7KZN9,Q9Y6M7,Q12959,Q9HC21,O95202,Q8IYU8,O75964,Q13423,Q9H2J7,O43772,Q9BPX6,P56385,Q9NW15,P46934,O75027,P16615,Q70HW3,P24539,P05067,P47985,Q96ES6,Q9BXP2,P12235,Q9UM00,Q9HD20,P42858,P00403,P61421,Q96GC9,P62942,Q8TAD4,Q9Y619,P05141,Q8WWC4,Q6P4Q7
Processes and pathways
GO Biological process
msigdb_gobp
256,7,137,136,145,146,532,22,150,151,279,405,155,410,31,161,289,162,297,418,168,416,170,300,50,181,438,448,75,475,338,214,87,341,216,466,220,481,105,239,361,502,375
1234,2181,748,162,2264,170,1443,1493,2788,2671,31,155,1751,216,712,2449,438,361,2351,1134,1988,826,2736,727,752,1790,1709,338,136,300,1944,864,580,2092,1846,2639,2956,7,181,1997,137,3119,2894,3043,1795,1797,1617,2864,341,416,1661,448,3131,777,3156,2004,636,1199,418,466,530,1623,481,145,994,1111,1717,2463,532,2648,2551,279,161,2273,2691,2853,256,2157,899,375,50,150,2831,410,2855,2777,876,105,502,1736,75,220,1969,677,3098,678,2381,297,1427,475,1973,1383,289,1599,879,146,405,87,904,168,22,1696,1980,824,214,1019,239,151
0.10296255264400622,-0.4252722805882104,0.44720170401297976,1.7905380137060627,-0.4809780479553145,1.744645033106282,-0.014190283332690111,-0.03822288271037234,-0.902417991440706,-0.7760255732552376,3.0502155042807657,1.8243030426289284,-0.18686982059176915,1.5248183397306079,0.48725623745593405,-0.5955921179420027,0.8907287812193003,1.0384916258428032,-0.5377405503528547,0.17094088359372295,-0.31690808027229783,0.38594722827302785,-0.8385853324054076,0.46730587199900714,0.44720170401297976,-0.21241421080737602,-0.16155054834083413,1.1013384647454063,1.9329933181047383,1.2368621349000533,-0.2904304927178063,0.36520852896444506,0.6601866548649779,-0.37059222129993374,-0.23818692761586824,-0.7452104629394918,-1.1364774707508174,3.5491802513502524,1.6858254775131012,-0.31690808027229783,1.9329933181047383,-1.7020688805675812,-1.034071137875609,-1.3514355919674153,-0.21241421080737602,-0.21241421080737602,-0.11157482962869282,-1.00064563472387,1.1013384647454063,0.9243562959106226,-0.13645324700708894,0.8737391734444331,-1.7850748625508288,0.42694183408394704,-2.0464349065431278,-0.31690808027229783,0.5847653265563068,0.12580968009238108,0.9243562959106226,0.8394016868466264,0.7334243460639536,-0.11157482962869282,0.8220511190203319,1.9009921408923331,0.259018664523886,0.19322985148629535,-0.16155054834083413,-0.5955921179420027,0.7334243460639536,-0.7452104629394918,-0.6545664545020534,1.3088453672804772,1.801854471157927,-0.4809780479553145,-0.7760255732552376,-0.9675653554604676,1.392310058750564,-0.39780592754705757,0.3443061993948582,1.006432544850282,2.760120300435202,1.8465093473865353,-0.934824649241834,0.9409967716069575,-0.9675653554604676,-0.8703399800828923,0.36520852896444506,2.2812210779922095,0.7869794546562088,-0.16155054834083413,2.5291039002629425,1.5248183397306079,-0.2904304927178063,0.5462030417796385,-1.5417758052175927,0.5462030417796385,-0.5377405503528547,1.2514414118114898,0.009638014956759703,0.8394016868466264,-0.2904304927178063,0.03326476765043723,1.280324185022697,-0.08691226787820137,0.36520852896444506,1.9009921408923331,0.9575234066599015,2.4176108705977826,0.3443061993948582,1.7791593908234755,3.143317850644801,-0.13645324700708894,-0.2904304927178063,0.40652433044515934,1.5376396248754793,0.259018664523886,1.446271558144171,1.8465093473865353
3,193
Calmodulin
7
14
2.46622
0.013655
Q8IYU8,Q9BPX6,Q9BRK5,Q14257,O43852,Q02818,P80303
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
410,297,167,241,372,55,24
372,2682,2322,1665,24,55,241,1412,2114,410,1047,562,297,167
1.006432544850282,-0.7760255732552376,-0.5092252179873332,-0.13645324700708894,3.1219129348274657,2.69120665946763,1.4329036514563958,0.009638014956759703,-0.37059222129993374,0.9409967716069575,0.23726642403703146,0.6970721128067479,1.2514414118114898,1.7791593908234755
3,193
Intracellular calcium-sensing protein
7
14
2.46622
0.013655
Q8IYU8,Q9BPX6,Q9BRK5,Q14257,O43852,Q02818,P80303
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
410,297,167,241,372,55,24
372,2682,2322,1665,24,55,241,1412,2114,410,1047,562,297,167
1.006432544850282,-0.7760255732552376,-0.5092252179873332,-0.13645324700708894,3.1219129348274657,2.69120665946763,1.4329036514563958,0.009638014956759703,-0.37059222129993374,0.9409967716069575,0.23726642403703146,0.6970721128067479,1.2514414118114898,1.7791593908234755
3,193
Hexosyltransferase activity
12
32
2.465157
0.013695
Q96L58,Q2TAA5,Q6ZXV5,P06865,Q9BV10,Q13126,Q10471,Q16880,P46977,O43505,P04062,Q9BT22
Functions
GO Molecular function
msigdb_gomf
291,326,559,293,199,73,489,273,206,275,122,316
2605,2394,275,1396,1166,1355,122,687,1030,1318,293,726,1064,1753,1358,945,206,1667,489,73,273,326,559,1765,1593,587,291,316,199,1222,1483,3160
-0.7146987125093559,-0.5665281275626076,1.3229726085415559,0.009638014956759703,0.1484683010782358,0.03326476765043723,2.153135324237049,0.5267030007716262,0.23726642403703146,0.0566926794738131,1.2514414118114898,0.46730587199900714,0.21533758545793177,-0.18686982059176915,0.03326476765043723,0.30200233977580343,1.5503857345605445,-0.13645324700708894,0.8045775073895869,2.5597189348802236,1.3370121237135937,1.1321439407679112,0.6970721128067479,-0.18686982059176915,-0.08691226787820137,0.6601866548649779,1.2659284528512882,1.1776036696350574,1.6130128562407051,0.12580968009238108,-0.014190283332690111,-2.1379443966160254
3,193
Regulation of mitochondrion organization
15
45
2.463894
0.013744
Q9H4A6,P21796,P02786,P05141,Q9NUQ9,Q9H3K2,O00165,Q9Y6C9,P12235,Q96A26,P42858,Q9GZY8,P30536,Q8N2A8,O14737
Processes and pathways
GO Biological process
msigdb_gobp
426,7,265,361,175,302,45,144,338,83,341,312,58,123,408
45,1098,408,2220,800,430,2223,1708,265,2140,361,1991,338,1399,7,2894,1657,58,3000,341,2685,2867,2364,3127,1962,1375,2160,123,876,2698,2163,83,1596,977,3098,2022,312,302,426,1185,792,175,1781,1310,144
2.832792341598909,0.19322985148629535,0.9409967716069575,-0.4529950413267082,0.40652433044515934,0.9076007240012801,-0.4529950413267082,-0.16155054834083413,1.3648314259575298,-0.39780592754705757,1.0384916258428032,-0.31690808027229783,1.1013384647454063,0.009638014956759703,3.5491802513502524,-1.034071137875609,-0.13645324700708894,2.6556741514333573,-1.2422071670625843,1.1013384647454063,-0.7760255732552376,-1.00064563472387,-0.5377405503528547,-1.743326090815665,-0.2904304927178063,0.03326476765043723,-0.39780592754705757,2.1436487406837603,0.36520852896444506,-0.7760255732552376,-0.39780592754705757,2.4420909128633217,-0.08691226787820137,0.28059656391052684,-1.5417758052175927,-0.31690808027229783,1.1925614229636166,1.2221896821440608,0.9243562959106226,0.1484683010782358,0.42694183408394704,1.7330122185385242,-0.18686982059176915,0.07992440556882748,1.9117156067218775
3,193
Protein localization to endoplasmic reticulum
14
34
2.4596
0.013909
Q15629,P24390,O43731,Q99442,O15258,P51572,Q9NQC3,Q15005,O43681,Q9H2M9,P61619,Q96HY6,Q9Y5M8,P46379
Processes and pathways
GO Biological process
msigdb_gobp
64,2,36,359,351,141,113,533,619,577,530,575,183,62
1394,351,619,36,1747,2310,2314,2712,1892,2,2683,62,1582,141,3059,2147,1544,2270,637,530,533,814,64,1172,2280,1215,575,359,577,113,2256,853,982,183
0.009638014956759703,1.0543605595517835,0.6038310370230041,2.96913415144942,-0.18686982059176915,-0.5092252179873332,-0.5092252179873332,-0.8071488815311059,-0.26419124276665046,3.7462657069794476,-0.7760255732552376,2.6339966056994,-0.08691226787820137,1.9223825076951602,-1.3886547156284181,-0.39780592754705757,-0.062462590653624604,-0.4809780479553145,0.5847653265563068,0.7334243460639536,0.7334243460639536,0.40652433044515934,2.62670988147732,0.1484683010782358,-0.4809780479553145,0.12580968009238108,0.6786968138424812,1.0543605595517835,0.6786968138424812,2.2364631467360248,-0.4529950413267082,0.38594722827302785,0.28059656391052684,1.6858254775131012
3,193
Establishment of protein localization to membrane
21
87
2.457876
0.013976
P43307,P27105,O60725,Q9NS69,Q9UPN3,O14737,Q96A33,Q15907,Q15070,Q8N2H4,Q9GZY8,P31751,P46379,Q15629,Q9P0J0,Q9Y512,Q9NPA0,Q9HD20,Q99442,Q15904,Q4J6C6
Processes and pathways
GO Biological process
msigdb_gobp
10,137,140,16,281,408,284,306,48,182,312,313,62,64,201,332,336,87,359,230,235
2344,1313,408,1394,858,619,1747,140,2533,2310,1316,1750,2449,1063,2314,2712,137,1657,2611,313,2543,2683,973,2097,10,62,2503,1582,1287,1950,2409,3059,1901,2270,637,530,3071,994,1717,1327,2551,2938,781,1549,814,48,64,230,306,235,2652,1295,661,2280,3007,817,182,1554,628,502,284,977,359,312,577,426,1008,1930,87,1057,336,792,16,1691,909,201,853,982,1696,1603,1014,281,1230,2083,332,1703,1272
-0.5377405503528547,0.0566926794738131,0.9409967716069575,0.009638014956759703,0.36520852896444506,0.6038310370230041,-0.18686982059176915,1.9223825076951602,-0.6545664545020534,-0.5092252179873332,0.0566926794738131,-0.18686982059176915,-0.5955921179420027,0.21533758545793177,-0.5092252179873332,-0.8071488815311059,1.9329933181047383,-0.13645324700708894,-0.7146987125093559,1.1776036696350574,-0.6545664545020534,-0.7760255732552376,0.28059656391052684,-0.37059222129993374,3.4750650461264545,2.6339966056994,-0.6249367779380635,-0.08691226787820137,0.07992440556882748,-0.2904304927178063,-0.5665281275626076,-1.3886547156284181,-0.26419124276665046,-0.4809780479553145,0.5847653265563068,0.7334243460639536,-1.426290709801661,0.259018664523886,-0.16155054834083413,0.0566926794738131,-0.6545664545020534,-1.101981072569348,0.42694183408394704,-0.062462590653624604,0.40652433044515934,2.800152733484291,2.62670988147732,1.4595591237186676,1.207423100369303,1.446271558144171,-0.7452104629394918,0.07992440556882748,0.5655565678430635,-0.4809780479553145,-1.2422071670625843,0.40652433044515934,1.6858254775131012,-0.062462590653624604,0.6038310370230041,0.7869794546562088,1.2946295225860096,0.28059656391052684,1.0543605595517835,1.1925614229636166,0.6786968138424812,0.9243562959106226,0.259018664523886,-0.26419124276665046,2.4176108705977826,0.23726642403703146,1.1167917984678513,0.42694183408394704,3.2657379732892013,-0.13645324700708894,0.3443061993948582,1.6006322940022837,0.38594722827302785,0.28059656391052684,-0.13645324700708894,-0.08691226787820137,0.259018664523886,1.3088453672804772,0.12580968009238108,-0.3436274762646461,1.1321439407679112,-0.13645324700708894,0.10296255264400622
3,193
Rho gtpases activate iqgaps
7
12
2.453818
0.014135
Q13885,P68371,Q13576,P04350,Q86VI3,Q9BVA1,Q9BUF5
Processes and pathways
Reactome Pathways
msigdb_reactome
612,320,135,390,433,404,378
390,2189,1502,1323,1622,320,691,135,612,433,378,404
0.9739374379111466,-0.4252722805882104,-0.03822288271037234,0.0566926794738131,-0.11157482962869282,1.1473959441543768,0.5267030007716262,1.9435485068003742,0.6227553904440447,0.9076007240012801,1.006432544850282,0.9575234066599015
3,193
Hormone metabolic process
11
32
2.453445
0.01415
Q53GQ0,Q8TAD4,Q9HB40,O95470,P16435,Q6NUM9,Q14849,O75844,Q9UBR2,P30536,P42892
Processes and pathways
GO Biological process
msigdb_gobp
236,105,42,171,299,301,74,81,244,58,91
1165,81,2397,171,712,567,1654,2842,299,58,91,3151,1324,2197,74,1463,236,301,1861,501,550,105,1341,2975,1969,3008,42,1092,370,244,2762,884
0.1484683010782358,2.4501778760429596,-0.5665281275626076,1.744645033106282,0.48725623745593405,0.6786968138424812,-0.13645324700708894,-0.9675653554604676,1.2368621349000533,2.6556741514333573,2.359178009634381,-2.0015302332107483,0.0566926794738131,-0.4252722805882104,2.536807538431712,-0.014190283332690111,1.446271558144171,1.2221896821440608,-0.23818692761586824,0.7869794546562088,0.7153141117668748,2.2812210779922095,0.0566926794738131,-1.1713430341599453,-0.2904304927178063,-1.2422071670625843,2.8899600348937455,0.21533758545793177,1.0225160037257737,1.4329036514563958,-0.8385853324054076,0.36520852896444506
3,193
Leukocyte mediated cytotoxicity
6
14
2.446373
0.01443
P68371,O15400,Q9NUQ9,P04439,P07437,P11279
Processes and pathways
GO Biological process
msigdb_gobp
320,413,175,233,401,309
413,1705,2575,1497,233,401,309,972,1360,487,320,930,175,1389
0.9243562959106226,-0.16155054834083413,-0.6844855875507391,-0.03822288271037234,1.446271558144171,0.9575234066599015,1.1925614229636166,0.28059656391052684,0.03326476765043723,0.8045775073895869,1.1473959441543768,0.32323817115644027,1.7330122185385242,0.03326476765043723
3,193
Er to golgi anterograde transport
30
82
2.444583
0.014502
P24390,Q14203,P04350,Q9BVA1,P61923,P62820,Q15363,Q9Y3B3,O43731,P49755,Q14789,Q13509,Q9BVK6,P55735,P68371,Q12893,P84085,Q9Y6Y8,O95249,Q13885,O15498,Q13190,Q12907,Q9UJW0,P53634,Q8N6H7,O75935,Q9UBR2,Q9BUF5,Q96PC5
Processes and pathways
Reactome Pathways
msigdb_reactome
2,639,390,404,657,531,29,30,36,417,674,691,444,440,320,325,458,476,348,612,604,354,490,231,487,500,240,244,378,386
1532,2635,798,3157,1394,604,1101,1837,36,2137,1574,240,2447,348,1194,942,390,1169,2,990,2503,2865,1754,1069,867,417,2266,2504,2267,487,2321,2547,440,831,657,531,1624,320,833,458,1327,325,490,2551,354,812,691,813,1041,612,639,1913,674,29,998,1172,1116,500,1679,1214,1259,1215,1681,2759,1347,386,2168,378,404,444,961,1183,744,2295,1933,244,231,986,30,710,1162,476
-0.062462590653624604,-0.7452104629394918,0.40652433044515934,-2.1379443966160254,0.009638014956759703,0.6227553904440447,0.19322985148629535,-0.23818692761586824,2.96913415144942,-0.39780592754705757,-0.08691226787820137,1.4329036514563958,-0.5955921179420027,1.070123936480939,0.12580968009238108,0.30200233977580343,0.9739374379111466,0.1484683010782358,3.7462657069794476,0.259018664523886,-0.6249367779380635,-1.00064563472387,-0.18686982059176915,0.21533758545793177,0.36520852896444506,0.9243562959106226,-0.4809780479553145,-0.6249367779380635,-0.4809780479553145,0.8045775073895869,-0.5092252179873332,-0.6545664545020534,0.8907287812193003,0.38594722827302785,0.5655565678430635,0.7334243460639536,-0.11157482962869282,1.1473959441543768,0.38594722827302785,0.8566305867164241,0.0566926794738131,1.1321439407679112,0.8045775073895869,-0.6545664545020534,1.0543605595517835,0.40652433044515934,0.5267030007716262,0.40652433044515934,0.23726642403703146,0.6227553904440447,0.5847653265563068,-0.26419124276665046,0.5462030417796385,3.078186020550252,0.259018664523886,0.1484683010782358,0.19322985148629535,0.7869794546562088,-0.13645324700708894,0.12580968009238108,0.10296255264400622,0.12580968009238108,-0.13645324700708894,-0.8385853324054076,0.0566926794738131,0.9902400838282385,-0.39780592754705757,1.006432544850282,0.9575234066599015,0.8907287812193003,0.30200233977580343,0.1484683010782358,0.46730587199900714,-0.4809780479553145,-0.26419124276665046,1.4329036514563958,1.4595591237186676,0.28059656391052684,3.067058131253242,0.5070546681307051,0.17094088359372295,0.8394016868466264
3,193
Calcium-binding protein
7
16
2.438149
0.014763
Q9BPX6,Q9BRK5,P43307,Q14257,O43852,Q02818,P80303
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
297,167,10,241,372,55,24
372,3087,2682,10,2322,1665,24,55,241,1412,2114,410,1047,562,297,167
1.006432544850282,-1.5028434769808663,-0.7760255732552376,3.4750650461264545,-0.5092252179873332,-0.13645324700708894,3.1219129348274657,2.69120665946763,1.4329036514563958,0.009638014956759703,-0.37059222129993374,0.9409967716069575,0.23726642403703146,0.6970721128067479,1.2514414118114898,1.7791593908234755
3,193
Monooxygenase activity
7
9
2.4367
0.014822
Q9BU89,Q15800,P30519,P09601,Q14534,Q6UW02,Q16850
Functions
GO Molecular function
msigdb_gomf
520,35,69,17,403,189,158
620,17,69,1902,403,35,158,189,520
0.6038310370230041,3.250973747172662,2.589810382359061,-0.26419124276665046,0.9575234066599015,2.975065555239934,1.8243030426289284,1.661830514045592,0.7514043268649677
3,193
Exocytic vesicle
21
41
2.435158
0.014885
Q9UI14,P61026,Q96A57,P50897,O15400,Q15019,Q15907,Q9BVK6,Q9BT78,P11279,Q9GZY8,P05067,O15126,Q92542,O76024,P20020,P61421,O60499,Q7L0J3,Q86Y82,O43760
Localization
GO Cellular component
msigdb_gocc
525,637,143,19,413,692,306,444,443,309,312,438,436,329,454,580,466,103,108,627,125
1098,1571,436,413,125,103,454,686,438,1990,309,580,1945,3119,19,1287,1454,3156,1901,1666,637,466,1407,2689,3077,692,783,2157,306,1143,108,627,329,1378,1767,143,443,444,312,525,986
0.19322985148629535,-0.08691226787820137,0.8907287812193003,0.9243562959106226,2.09550477869399,2.2812210779922095,0.8566305867164241,0.5267030007716262,0.8907287812193003,-0.31690808027229783,1.1925614229636166,0.6601866548649779,-0.2904304927178063,-1.7020688805675812,3.2108682288698214,0.07992440556882748,-0.014190283332690111,-2.0464349065431278,-0.26419124276665046,-0.13645324700708894,0.5847653265563068,0.8394016868466264,0.009638014956759703,-0.7760255732552376,-1.4643510697454634,0.5267030007716262,0.42694183408394704,-0.39780592754705757,1.207423100369303,0.17094088359372295,2.245500235348313,0.6038310370230041,1.1321439407679112,0.03326476765043723,-0.18686982059176915,1.9117156067218775,0.8907287812193003,0.8907287812193003,1.1925614229636166,0.7514043268649677,0.28059656391052684
3,193
Inorganic anion transmembrane transporter activity
8
21
2.432388
0.015
P21796,Q9NW15,Q9C0H2,P45880,Q9Y277,Q9UBX3,Q9Y6M7,P51798
Functions
GO Molecular function
msigdb_gomf
7,168,13,15,247,54,151,184
2964,619,3092,7,888,15,3156,184,636,870,256,1921,929,474,475,13,168,54,247,2443,151
-1.1713430341599453,0.6038310370230041,-1.5417758052175927,3.5491802513502524,0.3443061993948582,3.285196134499565,-2.0464349065431278,1.6738619652882785,0.5847653265563068,0.36520852896444506,1.392310058750564,-0.26419124276665046,0.32323817115644027,0.8394016868466264,0.8394016868466264,3.351325980333631,1.7791593908234755,2.732890881137026,1.419454626258951,-0.5665281275626076,1.8465093473865353
3,193
Recruitment of numa to mitotic centrosomes
24
36
2.431818
0.015023
Q14203,P04350,P07437,Q9BVA1,P30153,O94927,Q13409,Q13561,Q9BSJ2,Q13509,Q96RT7,Q96CS2,P06493,P68371,Q15154,Q9H6D7,P43034,P61163,Q96CW5,Q13885,O75935,O95684,Q7Z4H7,Q9BUF5
Processes and pathways
Reactome Pathways
msigdb_reactome
639,390,401,404,917,290,812,813,959,691,576,574,439,320,585,197,583,831,741,612,240,118,376,378
240,290,118,390,439,401,1063,917,1658,583,1107,831,2410,1623,1624,320,812,691,813,612,2274,639,1913,2776,585,1916,976,376,574,741,576,2381,959,378,404,197
1.4329036514563958,1.2659284528512882,2.1813172981447764,0.9739374379111466,0.8907287812193003,0.9575234066599015,0.21533758545793177,0.32323817115644027,-0.13645324700708894,0.6601866548649779,0.19322985148629535,0.38594722827302785,-0.5665281275626076,-0.11157482962869282,-0.11157482962869282,1.1473959441543768,0.40652433044515934,0.5267030007716262,0.40652433044515934,0.6227553904440447,-0.4809780479553145,0.5847653265563068,-0.26419124276665046,-0.8703399800828923,0.6601866548649779,-0.26419124276665046,0.28059656391052684,1.006432544850282,0.6786968138424812,0.46730587199900714,0.6786968138424812,-0.5377405503528547,0.30200233977580343,1.006432544850282,0.9575234066599015,1.6253223144467295
3,193
Cellular monovalent inorganic cation homeostasis
8
26
2.423064
0.01539
Q15904,Q9Y487,Q93050,O75503,Q8N511,Q9HC07,P50897,Q9Y6M7
Processes and pathways
GO Biological process
msigdb_gobp
230,71,138,104,49,146,19,151
104,686,712,2449,1134,3092,2892,1136,19,1287,3156,2004,636,466,1328,230,49,315,138,819,146,1696,1980,71,2443,151
2.2812210779922095,0.5267030007716262,0.48725623745593405,-0.5955921179420027,0.17094088359372295,-1.5417758052175927,-1.034071137875609,0.17094088359372295,3.2108682288698214,0.07992440556882748,-2.0464349065431278,-0.31690808027229783,0.5847653265563068,0.8394016868466264,0.0566926794738131,1.4595591237186676,2.7869149799952893,1.1776036696350574,1.9329933181047383,0.40652433044515934,1.9009921408923331,-0.13645324700708894,-0.2904304927178063,2.582335824717171,-0.5665281275626076,1.8465093473865353
3,193
Mitochondrial protein import
18
35
2.422824
0.0154
O60830,Q99595,P21796,Q8N4H5,O43615,Q9Y512,Q5JRX3,Q9NS69,P12235,Q13505,Q3ZCQ8,O14925,Q10713,Q15388,P12236,O75746,O96008,Q9UJS0
Processes and pathways
Reactome Pathways
msigdb_reactome
0,3,7,41,414,332,625,16,338,51,557,211,497,280,217,527,651,428
211,414,0,3066,1610,2788,527,1316,651,1134,752,3129,338,217,7,1997,3155,1507,497,51,280,557,625,41,2832,3,3009,2253,16,698,428,1230,332,1703,1272
1.5376396248754793,0.9243562959106226,4.042548479567164,-1.426290709801661,-0.11157482962869282,-0.902417991440706,0.7334243460639536,0.0566926794738131,0.5655565678430635,0.17094088359372295,0.44720170401297976,-1.7850748625508288,1.1013384647454063,1.5248183397306079,3.5491802513502524,-0.31690808027229783,-2.0464349065431278,-0.03822288271037234,0.7869794546562088,2.746560633651398,1.3088453672804772,0.6970721128067479,0.6038310370230041,2.8899600348937455,-0.934824649241834,3.6753208773984025,-1.2422071670625843,-0.4529950413267082,3.2657379732892013,0.5267030007716262,0.9243562959106226,0.12580968009238108,1.1321439407679112,-0.13645324700708894,0.10296255264400622
3,193
Sphingolipid pathway
6
9
2.420755
0.015488
Q06136,O95470,Q16880,Q13510,P04062,Q96G23
Processes and pathways
WikiPathways
msigdb_wp
99,171,273,116,122,159
303,1060,171,122,3096,99,116,273,159
1.207423100369303,0.21533758545793177,1.744645033106282,2.153135324237049,-1.5417758052175927,2.3075717767503545,2.1998773817605315,1.3370121237135937,1.8243030426289284
3,193
Tetrapyrrole binding
11
17
2.555854
0.010593
Q7KZN9,O43169,Q16850,O00264,Q9NRV9,P09601,Q8WUJ1,O15173,Q9H7Z7,P22033,P30519
Functions
GO Molecular function
msigdb_gomf
34,3,72,230,108,16,49,86,87,26,30
230,86,3,924,16,525,26,30,415,72,34,49,1343,248,1815,87,108
1.3957065387939775,2.3141287494435288,4.538070853810301,0.2845952066465906,3.569896002615672,0.6895204380991842,3.3115497465465826,3.2359184398648075,0.8916563244233383,2.4150687298866993,3.120881360315947,2.763623938626272,0.02005630675687408,1.3453623026039885,-0.21301107990823281,2.299582999979804,2.137439917028965
3,158
Vitamin transport
7
10
2.527982
0.011472
P41440,O14678,P11166,P38435,Q9H2D1,Q9HC21,Q8WTV0
Processes and pathways
GO Biological process
msigdb_gobp
352,324,90,205,81,219,153
324,430,90,205,352,153,81,219,1941,1123
1.0875520381228632,0.8553812456932677,2.285005355240521,1.5116725479401998,1.017012356409468,1.8006928640223112,2.38638442152182,1.4622272217645225,-0.27814567078633884,0.16390374170685057
3,158
Vitamin transmembrane transporter activity
6
9
2.520403
0.011722
P41440,O14678,P38435,Q9H2D1,Q9HC21,P11166
Functions
GO Molecular function
msigdb_gomf
352,324,205,81,219,90
324,430,90,205,352,81,219,1941,1123
1.0875520381228632,0.8553812456932677,2.285005355240521,1.5116725479401998,1.017012356409468,2.38638442152182,1.4622272217645225,-0.27814567078633884,0.16390374170685057
3,158
Mitochondrial nucleotide transporter subfamily
7
8
2.457419
0.013994
Q70HW3,P12236,Q9H2D1,Q6NUK1,Q9HC21,P12235,O43808
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
39,608,81,495,219,276,191
191,607,276,608,495,39,81,219
1.6255994131631313,0.5764726853733471,1.2091538203670413,0.5764726853733471,0.7267565302959491,2.9379860023464293,2.38638442152182,1.4622272217645225
3,158
Amino acid import
7
9
2.437322
0.014796
Q15758,Q96NB2,P30825,Q9H9B4,Q9UPY5,P08195,O75915
Processes and pathways
GO Biological process
msigdb_gobp
416,322,387,557,298,461,122
122,1198,461,387,570,416,322,557,298
2.0017562121267485,0.1026646339122274,0.8005763108055255,0.9456831946575108,0.6332504843645337,0.8916563244233383,1.1050658553906163,0.6520630652256373,1.174645451401165
3,158
Fatty acid transmembrane transport
6
7
2.39954
0.016416
P50416,O14678,P28288,P23786,O43772,P11166
Processes and pathways
GO Biological process
msigdb_gobp
67,324,386,107,112,90
324,112,90,107,386,447,67
1.0875520381228632,2.062404795850602,2.285005355240521,2.137439917028965,0.9456831946575108,0.8371655762723303,2.5285896871776092
3,158
Cristae formation
8
10
2.370288
0.017774
O95202,Q5XKP0,Q9Y4W6,Q6UXV4,Q96E52,Q9Y512,Q9NX63,Q9BUR5
Processes and pathways
GO Biological process
msigdb_gobp
196,106,592,145,436,376,316,187
196,614,106,145,436,187,1153,316,592,376
1.5770182117754088,0.5764726853733471,2.152345252225145,1.8632174365294025,0.8553812456932677,1.6417128095285944,0.14355800544070552,1.1225318181233481,0.6143814788140437,0.9814476823334446
3,158
Epiphyseal stippling
6
10
2.325094
0.020067
O00116,Q14739,P08236,P38435,O75381,Q15738
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
224,253,235,205,113,181
224,2395,113,235,2085,205,398,253,181,1260
1.4290524817880874,-0.5458927047153141,2.062404795850602,1.3789687523304992,-0.3660890405758847,1.5116725479401998,0.9277252404864844,1.3284931338845052,1.6577864035634409,0.08211600805520915
3,158
Left ventricular systolic dysfunction
6
10
2.316019
0.020557
O75844,P49748,Q7LG56,Q9UHN1,P12235,P22413
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
97,129,402,407,276,27
97,782,276,27,129,1741,402,518,1548,407
2.2263727003912277,0.40298796762993605,1.2091538203670413,3.299002303914967,1.955900389628187,-0.1914530239598831,0.9277252404864844,0.7081659633011456,-0.08478723501183005,0.9277252404864844
3,158
Amino-acid transport
7
10
2.309121
0.020937
Q15758,Q96NB2,P30825,Q9UPY5,P08195,Q6P4A7,Q8TD22
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
416,322,387,298,461,46,498
461,387,416,46,498,322,1287,850,557,298
0.8005763108055255,0.9456831946575108,0.8916563244233383,2.790743261240197,0.7267565302959491,1.1050658553906163,0.061498752291908376,0.3637731497479283,0.6520630652256373,1.174645451401165
3,158
Dicarboxylic acid transmembrane transporter activity
6
8
2.242234
0.024946
Q15758,P41440,Q02978,Q9BQT8,Q9UBX3,O75746
Functions
GO Molecular function
msigdb_gomf
416,352,306,147,182,469
469,352,306,416,147,619,182,801
0.7822020382068811,1.017012356409468,1.13995021488938,0.8916563244233383,1.8632174365294025,0.5764726853733471,1.6577864035634409,0.40298796762993605
3,158
Mitochondrial long chain fatty acid betaoxidation
11
13
2.233892
0.02549
P49748,P50416,P40939,O60488,P23786,P22307,P42126,O43772,P11310,Q16836,P33121
Processes and pathways
WikiPathways
msigdb_wp
129,67,260,69,107,609,79,112,364,493,447
112,69,656,364,609,107,447,260,79,129,67,493,1722
2.062404795850602,2.4436302614050165,0.5191767799228211,0.9992548415205185,0.5764726853733471,2.137439917028965,0.8371655762723303,1.3115796618320061,2.38638442152182,1.955900389628187,2.5285896871776092,0.7267565302959491,-0.16997070939394682
3,158
Ether metabolic process
6
10
2.228184
0.025868
O00116,P07099,P34913,Q6PIU2,Q7L5N7,O15228
Processes and pathways
GO Biological process
msigdb_gobp
224,33,8,109,210,370
224,370,33,8,685,1912,488,109,210,671
1.4290524817880874,0.9814476823334446,3.120881360315947,4.399980885657888,0.4999611899716947,-0.27814567078633884,0.7452924964887262,2.1225009119684284,1.4952326929339315,0.5191767799228211
3,158
Mitochondrial carrier protein [IPR002067]
9
11
2.223093
0.02621
Q9H936,P12236,Q6NUK1,Q9BQT8,Q9HC21,O75746,P12235,O43808,P53007
Sequence
InterPro Family
interpro_family
619,608,495,147,219,469,276,191,344
191,469,607,276,608,344,495,147,619,219,801
1.6255994131631313,0.7822020382068811,0.5764726853733471,1.2091538203670413,0.5764726853733471,1.0347205324208402,0.7267565302959491,1.8632174365294025,0.5764726853733471,1.4622272217645225,0.40298796762993605
3,158
Class i peroxisomal membrane protein import
8
10
2.218446
0.026524
P28288,O75381,Q9NR77,Q9Y3D6,P51648,P40855,Q8TB36,O43808
Processes and pathways
Reactome Pathways
msigdb_reactome
386,113,606,582,84,398,283,191
191,113,386,398,84,812,645,283,606,582
1.6255994131631313,2.062404795850602,0.9456831946575108,0.9277252404864844,2.3286427577430664,0.3834113757849999,0.5383336290729737,1.2091538203670413,0.59545567248021,0.6332504843645337
3,158
Transport of inorganic cations anions and amino acids oligopeptides
9
13
2.203873
0.027533
Q15758,P30626,P04920,P30825,Q9Y6M7,Q70HW3,Q9UPY5,P08195,Q9UBX3
Processes and pathways
Reactome Pathways
msigdb_reactome
416,192,285,387,593,39,298,461,182
285,461,192,387,1446,416,39,1287,850,619,182,298,593
1.1919228549907164,0.8005763108055255,1.6094459955732547,0.9456831946575108,-0.04263501903286422,0.8916563244233383,2.9379860023464293,0.061498752291908376,0.3637731497479283,0.5764726853733471,1.6577864035634409,1.174645451401165,0.6143814788140437
3,158
Retinal vascular tortuosity
6
16
2.196516
0.028055
Q15056,O43709,O75306,P21964,P03886,P03905
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
328,116,152,58,29,184
1522,116,152,806,29,184,58,1275,1655,1496,328,1343,1215,987,2023,395
-0.08478723501183005,2.0472948818905308,1.8163800774976575,0.3834113757849999,3.2485817472122127,1.6417128095285944,2.612484803818415,0.061498752291908376,-0.1485635494914289,-0.06367496504356772,1.0875520381228632,0.02005630675687408,0.1026646339122274,0.24462498968873161,-0.3219585207950413,0.9456831946575108
3,158
Glycerol ether metabolic process
6
8
2.183556
0.028995
O00116,Q6IAN0,Q6PIU2,Q8WVX9,Q7L5N7,O15228
Processes and pathways
GO Biological process
msigdb_gobp
224,488,109,671,210,370
224,370,685,1912,488,109,210,671
1.4290524817880874,0.9814476823334446,0.4999611899716947,-0.27814567078633884,0.7452924964887262,2.1225009119684284,1.4952326929339315,0.5191767799228211
3,158
Solute anion antiporter activity
6
7
2.149391
0.031603
P41440,P04920,Q9UPY5,P12236,Q02978,P12235
Functions
GO Molecular function
msigdb_gomf
352,285,298,608,306,276
285,607,276,608,352,306,298
1.1919228549907164,0.5764726853733471,1.2091538203670413,0.5764726853733471,1.017012356409468,1.13995021488938,1.174645451401165
3,158
Mitochondrial complex iv assembly
6
12
2.147439
0.031758
Q7KZN9,P15954,P00403,P13073,P10606,P14406
Processes and pathways
WikiPathways
msigdb_wp
34,325,267,173,431,91
1069,1126,267,1300,431,173,91,325,1130,34,772,540
0.18418282942859027,0.14355800544070552,1.2776187715585925,0.04081235702067276,0.8553812456932677,1.6898150509964927,2.285005355240521,1.0875520381228632,0.14355800544070552,3.120881360315947,0.4225033519714953,0.6895204380991842
3,158
SLC25 family of mitochondrial transporters
17
20
2.145665
0.0319
Q9H936,Q70HW3,Q9Y6C9,P12236,Q00325,Q9H2D1,O43772,Q02978,Q9BQT8,Q6NUK1,Q9UBX3,Q9HC21,O75746,P12235,Q9NZJ7,O43808,P53007
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
619,39,143,608,463,81,112,306,147,495,182,219,469,276,154,191,344
112,191,469,607,276,608,344,463,306,495,39,147,81,619,219,154,182,801,1262,143
2.062404795850602,1.6255994131631313,0.7822020382068811,0.5764726853733471,1.2091538203670413,0.5764726853733471,1.0347205324208402,0.8005763108055255,1.13995021488938,0.7267565302959491,2.9379860023464293,1.8632174365294025,2.38638442152182,0.5764726853733471,1.4622272217645225,1.8006928640223112,1.6577864035634409,0.40298796762993605,0.08211600805520915,1.8787557838516555
3,158
Mitochondrial carrier domain superfamily [IPR023395]
17
20
2.145665
0.0319
Q9H936,Q70HW3,Q9Y6C9,P12236,Q00325,Q9H2D1,O43772,Q02978,Q9BQT8,Q6NUK1,Q9UBX3,Q9HC21,O75746,P12235,Q9NZJ7,O43808,P53007
Sequence
InterPro Superfamily
interpro_homologous_superfamily
619,39,143,608,463,81,112,306,147,495,182,219,469,276,154,191,344
112,191,469,607,276,608,344,463,306,495,39,147,81,619,219,154,182,801,1262,143
2.062404795850602,1.6255994131631313,0.7822020382068811,0.5764726853733471,1.2091538203670413,0.5764726853733471,1.0347205324208402,0.8005763108055255,1.13995021488938,0.7267565302959491,2.9379860023464293,1.8632174365294025,2.38638442152182,0.5764726853733471,1.4622272217645225,1.8006928640223112,1.6577864035634409,0.40298796762993605,0.08211600805520915,1.8787557838516555
3,158
Mitochondrial substrate/solute carrier [IPR018108]
17
20
2.145665
0.0319
Q9H936,Q70HW3,Q9Y6C9,P12236,Q00325,Q9H2D1,O43772,Q02978,Q9BQT8,Q6NUK1,Q9UBX3,Q9HC21,O75746,P12235,Q9NZJ7,O43808,P53007
Sequence
InterPro Repeat
interpro_repeat
619,39,143,608,463,81,112,306,147,495,182,219,469,276,154,191,344
112,191,469,607,276,608,344,463,306,495,39,147,81,619,219,154,182,801,1262,143
2.062404795850602,1.6255994131631313,0.7822020382068811,0.5764726853733471,1.2091538203670413,0.5764726853733471,1.0347205324208402,0.8005763108055255,1.13995021488938,0.7267565302959491,2.9379860023464293,1.8632174365294025,2.38638442152182,0.5764726853733471,1.4622272217645225,1.8006928640223112,1.6577864035634409,0.40298796762993605,0.08211600805520915,1.8787557838516555
3,158
L alpha amino acid transmembrane transport
8
12
2.140446
0.032319
Q15758,Q15041,P30825,Q9UPY5,P08195,O60831,O75746,O75915
Processes and pathways
GO Biological process
msigdb_gobp
416,570,387,298,461,56,469,122
56,469,122,1198,461,387,570,416,619,801,298,1262
2.6263659087678035,0.7822020382068811,2.0017562121267485,0.1026646339122274,0.8005763108055255,0.9456831946575108,0.6332504843645337,0.8916563244233383,0.5764726853733471,0.40298796762993605,1.174645451401165,0.08211600805520915
3,158
P-type ATPase [IPR001757]
7
8
2.122535
0.033793
P05023,P98194,P23634,P35670,Q9HD20,P16615,P20020
Sequence
InterPro Family
interpro_family
726,512,542,763,269,140,277
726,140,277,542,763,512,843,269
0.46135218218264096,1.8787557838516555,1.2091538203670413,0.6708195936494596,0.4225033519714953,0.7081659633011456,0.3637731497479283,1.2776187715585925
3,158
P-type ATPase, phosphorylation site [IPR018303]
7
8
2.122535
0.033793
P05023,P98194,P23634,P35670,Q9HD20,P16615,P20020
Sequence
InterPro PTM
interpro_ptm
726,512,542,763,269,140,277
726,140,277,542,763,512,843,269
0.46135218218264096,1.8787557838516555,1.2091538203670413,0.6708195936494596,0.4225033519714953,0.7081659633011456,0.3637731497479283,1.2776187715585925
3,158
P-type ATPase, haloacid dehalogenase domain [IPR044492]
7
8
2.122535
0.033793
P05023,P98194,P23634,P35670,Q9HD20,P16615,P20020
Sequence
InterPro Domain
interpro_domain
726,512,542,763,269,140,277
726,140,277,542,763,512,843,269
0.46135218218264096,1.8787557838516555,1.2091538203670413,0.6708195936494596,0.4225033519714953,0.7081659633011456,0.3637731497479283,1.2776187715585925
3,158
P-type ATPase, cytoplasmic domain N [IPR023299]
7
8
2.122535
0.033793
P05023,P98194,P23634,P35670,Q9HD20,P16615,P20020
Sequence
InterPro Superfamily
interpro_homologous_superfamily
726,512,542,763,269,140,277
726,140,277,542,763,512,843,269
0.46135218218264096,1.8787557838516555,1.2091538203670413,0.6708195936494596,0.4225033519714953,0.7081659633011456,0.3637731497479283,1.2776187715585925
3,158
P-type ATPase, transmembrane domain superfamily [IPR023298]
7
8
2.122535
0.033793
P05023,P98194,P23634,P35670,Q9HD20,P16615,P20020
Sequence
InterPro Superfamily
interpro_homologous_superfamily
726,512,542,763,269,140,277
726,140,277,542,763,512,843,269
0.46135218218264096,1.8787557838516555,1.2091538203670413,0.6708195936494596,0.4225033519714953,0.7081659633011456,0.3637731497479283,1.2776187715585925
3,158
P-type ATPase, A domain superfamily [IPR008250]
7
8
2.122535
0.033793
P05023,P98194,P23634,P35670,Q9HD20,P16615,P20020
Sequence
InterPro Superfamily
interpro_homologous_superfamily
726,512,542,763,269,140,277
726,140,277,542,763,512,843,269
0.46135218218264096,1.8787557838516555,1.2091538203670413,0.6708195936494596,0.4225033519714953,0.7081659633011456,0.3637731497479283,1.2776187715585925
3,158
Positive regulation of response to endoplasmic reticulum stress
6
9
2.113628
0.034547
P57088,Q9UHD9,Q07812,Q4ZIN3,Q9UMX0,P51572
Processes and pathways
GO Biological process
msigdb_gobp
661,341,209,114,155,527
724,1007,1331,527,661,209,114,341,155
0.46135218218264096,0.22454297991627103,0.02005630675687408,0.6895204380991842,0.5191767799228211,1.4952326929339315,2.062404795850602,1.0523796720755456,1.8006928640223112
3,158
P-type ATPases
8
9
2.103564
0.035417
P05023,P98194,P23634,P35670,P05026,P16615,P20020,P54709
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
726,512,542,763,286,140,277,730
726,286,140,277,542,763,730,512,843
0.46135218218264096,1.1919228549907164,1.8787557838516555,1.2091538203670413,0.6708195936494596,0.4225033519714953,0.46135218218264096,0.7081659633011456,0.3637731497479283
3,158
Regulation of steroid biosynthetic process
8
11
2.102836
0.03548
Q6P1A2,Q13510,P30536,P16435,O94905,Q13131,Q9UHI6,O75477
Processes and pathways
GO Biological process
msigdb_gobp
193,643,104,705,474,733,257,124
124,474,726,705,104,733,643,1112,193,1260,257
1.986506418312162,0.763774215698525,0.46135218218264096,0.48068645890860423,2.1672170851267882,0.46135218218264096,0.5383336290729737,0.16390374170685057,1.5932523359955717,0.08211600805520915,1.3284931338845052
3,158
Long chain fatty acid transport
8
14
2.101116
0.035631
P50416,P14174,O14678,P28288,P11166,P23786,O43772,O14975
Processes and pathways
GO Biological process
msigdb_gobp
67,6,324,386,90,107,112,59
324,59,112,656,2563,2329,90,6,107,386,447,67,1628,2284
1.0875520381228632,2.5985749452384983,2.062404795850602,0.5191767799228211,-0.6610487295793153,-0.5004387275975467,2.285005355240521,4.4106989500597615,2.137439917028965,0.9456831946575108,0.8371655762723303,2.5285896871776092,-0.12723096454080488,-0.45532380107244474
3,158
oxidase
6
13
2.095259
0.036148
P36551,P15954,P13073,P50336,P14406,O14548
Functions
Panther Protein class
panther_protein_class
296,325,173,141,91,95
95,1126,1266,831,431,173,91,325,1130,296,141,1755,2377
2.2410794907590836,0.14355800544070552,0.061498752291908376,0.3637731497479283,0.8553812456932677,1.6898150509964927,2.285005355240521,1.0875520381228632,0.14355800544070552,1.174645451401165,1.8787557838516555,-0.1914530239598831,-0.5231229824007191
3,158
L amino acid transport
9
14
2.092426
0.0364
Q15758,Q15041,P30825,Q9H9B4,Q9UPY5,P08195,O60831,O75746,O75915
Processes and pathways
GO Biological process
msigdb_gobp
416,570,387,557,298,461,56,469,122
56,469,122,1198,461,387,570,416,1287,619,557,801,298,1262
2.6263659087678035,0.7822020382068811,2.0017562121267485,0.1026646339122274,0.8005763108055255,0.9456831946575108,0.6332504843645337,0.8916563244233383,0.061498752291908376,0.5764726853733471,0.6520630652256373,0.40298796762993605,1.174645451401165,0.08211600805520915
3,158
Posterior embryotoxon
6
16
2.090961
0.036532
Q9Y4P3,Q15056,O75381,P40855,O43709,P21964
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
395,328,113,398,116,58
1522,116,113,58,1275,398,415,1655,1496,328,985,1343,1215,987,2023,395
-0.08478723501183005,2.0472948818905308,2.062404795850602,2.612484803818415,0.061498752291908376,0.9277252404864844,0.8916563244233383,-0.1485635494914289,-0.06367496504356772,1.0875520381228632,0.24462498968873161,0.02005630675687408,0.1026646339122274,0.24462498968873161,-0.3219585207950413,0.9456831946575108
3,158
Mib complex
7
11
2.079057
0.037612
Q5HYI7,Q5XKP0,Q13505,Q6UXV4,Q9Y512,Q9NX63,Q9BUR5
Localization
GO Cellular component
msigdb_gocc
487,106,174,145,376,316,187
1194,2402,174,614,487,106,145,187,1153,316,376
0.1026646339122274,-0.5458927047153141,1.6898150509964927,0.5764726853733471,0.7452924964887262,2.152345252225145,1.8632174365294025,1.6417128095285944,0.14355800544070552,1.1225318181233481,0.9814476823334446
3,158
Lamin binding
6
8
2.069495
0.0385
Q14739,Q9ULX6,P42167,Q5JTV8,Q5SNT2,O94901
Functions
GO Molecular function
msigdb_gomf
253,701,241,749,118,429
429,1200,241,253,749,118,815,701
0.8553812456932677,0.1026646339122274,1.362187424133538,1.3284931338845052,0.4419579509419327,2.0472948818905308,0.3834113757849999,0.4999611899716947
3,158
Endoplasmic reticulum tubular network
7
13
2.058516
0.039541
Q9H6H4,Q8NHH9,Q13586,P50402,P61026,Q00765,Q9NQC3
Localization
GO Cellular component
msigdb_gocc
139,404,411,57,157,220,62
57,157,220,1497,411,1803,1078,546,404,716,139,937,62
2.6263659087678035,1.7849679388816513,1.445661130467825,-0.06367496504356772,0.9097163905743372,-0.21301107990823281,0.18418282942859027,0.6708195936494596,0.9277252404864844,0.48068645890860423,1.8942574017354559,0.2845952066465906,2.5985749452384983
3,158
L amino acid transmembrane transporter activity
7
10
2.055151
0.039864
Q15758,Q9H936,P30825,Q9H9B4,Q9UPY5,P08195,O75746
Functions
GO Molecular function
msigdb_gomf
416,619,387,557,298,461,469
469,461,387,416,1287,619,557,801,298,1262
0.7822020382068811,0.8005763108055255,0.9456831946575108,0.8916563244233383,0.061498752291908376,0.5764726853733471,0.6520630652256373,0.40298796762993605,1.174645451401165,0.08211600805520915
3,158
Regulation of steroid metabolic process
11
15
2.036841
0.041666
Q6P1A2,P49748,P34913,Q13510,P30536,P16435,O94905,Q6IAA8,Q13131,Q9UHI6,O75477
Processes and pathways
GO Biological process
msigdb_gobp
193,129,8,643,104,705,474,401,733,257,124
124,474,726,705,104,8,129,733,643,1112,401,193,1260,257,1682
1.986506418312162,0.763774215698525,0.46135218218264096,0.48068645890860423,2.1672170851267882,4.399980885657888,1.955900389628187,0.46135218218264096,0.5383336290729737,0.16390374170685057,0.9277252404864844,1.5932523359955717,0.08211600805520915,1.3284931338845052,-0.1485635494914289
3,158
Peroxisome organization
7
12
2.035386
0.041812
O14678,P28288,O75381,Q7Z434,Q9GZY8,Q9Y3D6,P40855
Processes and pathways
GO Biological process
msigdb_gobp
324,386,113,177,50,582,398
1156,324,1231,113,609,386,398,177,1851,50,826,582
0.12314513367219083,1.0875520381228632,0.08211600805520915,2.062404795850602,0.5764726853733471,0.9456831946575108,0.9277252404864844,1.673820412313262,-0.23464547108069847,2.750023299518009,0.3834113757849999,0.6332504843645337
3,158
Ppar signaling pathway
13
18
2.012582
0.044159
P50416,O60488,Q9UKU0,O14975,P23786,O00767,P22307,P11310,Q15067,P48163,P33121,O95864,O15254
Processes and pathways
KEGG Pathways
msigdb_kegg
67,69,70,59,107,75,609,364,597,526,447,123,189
75,59,189,69,656,123,2293,364,609,107,447,526,67,1539,597,1626,1628,70
2.400741995826197,2.5985749452384983,1.6255994131631313,2.4436302614050165,0.5191767799228211,2.0017562121267485,-0.47783923318812466,0.9992548415205185,0.5764726853733471,2.137439917028965,0.8371655762723303,0.6895204380991842,2.5285896871776092,-0.08478723501183005,0.59545567248021,-0.12723096454080488,-0.12723096454080488,2.4436302614050165
3,158
Ppar signaling pathway
13
18
2.012582
0.044159
P50416,O60488,Q9UKU0,O14975,P23786,O00767,P22307,P11310,Q15067,P48163,P33121,O95864,O15254
Processes and pathways
WikiPathways
msigdb_wp
67,69,70,59,107,75,609,364,597,526,447,123,189
75,59,189,69,656,123,2293,364,609,107,447,526,67,1539,597,1626,1628,70
2.400741995826197,2.5985749452384983,1.6255994131631313,2.4436302614050165,0.5191767799228211,2.0017562121267485,-0.47783923318812466,0.9992548415205185,0.5764726853733471,2.137439917028965,0.8371655762723303,0.6895204380991842,2.5285896871776092,-0.08478723501183005,0.59545567248021,-0.12723096454080488,-0.12723096454080488,2.4436302614050165
3,158
Porphyrin and chlorophyll metabolism
8
14
2.006205
0.044834
Q7KZN9,P36551,P08236,P50336,P09601,P22830,Q96EY8,P30519
Processes and pathways
KEGG Pathways
msigdb_kegg
34,296,235,141,16,21,248,30
3044,2329,235,2592,16,21,30,296,141,2133,415,1709,34,248
-1.3766514779344772,-0.5004387275975467,1.3789687523304992,-0.6843466318407745,3.569896002615672,3.3863568791785137,3.2359184398648075,1.174645451401165,1.8787557838516555,-0.3882750295201283,0.8916563244233383,-0.16997070939394682,3.120881360315947,1.3453623026039885
3,158
Ion transport by p type atpases
10
12
1.995478
0.045991
P30626,P05023,P98194,P23634,P35670,P05026,Q9HD20,P16615,P20020,P54709
Processes and pathways
Reactome Pathways
msigdb_reactome
192,726,512,542,763,286,269,140,277,730
726,286,140,277,542,192,763,730,512,1576,843,269
0.46135218218264096,1.1919228549907164,1.8787557838516555,1.2091538203670413,0.6708195936494596,1.6094459955732547,0.4225033519714953,0.46135218218264096,0.7081659633011456,-0.10597238172521264,0.3637731497479283,1.2776187715585925
3,158
Oxidase
9
17
1.979844
0.047721
O15254,P49748,O43169,Q9H845,P36551,P15954,P11310,P14406,O14548
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
189,129,3,392,296,325,364,91,95
95,189,3,1126,831,431,364,2594,91,325,1130,885,296,129,597,1755,392
2.2410794907590836,1.6255994131631313,4.538070853810301,0.14355800544070552,0.3637731497479283,0.8553812456932677,0.9992548415205185,-0.6843466318407745,2.285005355240521,1.0875520381228632,0.14355800544070552,0.3243100651574681,1.174645451401165,1.955900389628187,0.59545567248021,-0.1914530239598831,0.9456831946575108
3,158
Cytochrome complex
11
17
1.975791
0.048178
Q7KZN9,P31930,P15954,P00403,P13073,Q9UDW1,O14949,P10606,P14406,P22695,O14548
Localization
GO Cellular component
msigdb_gocc
34,659,325,267,173,175,211,431,91,626,95
1069,95,211,267,924,1300,431,173,91,1161,325,1130,626,659,34,175,702
0.18418282942859027,2.2410794907590836,1.478750996384843,1.2776187715585925,0.2845952066465906,0.04081235702067276,0.8553812456932677,1.6898150509964927,2.285005355240521,0.12314513367219083,1.0875520381228632,0.14355800544070552,0.5574321335531693,0.5191767799228211,3.120881360315947,1.6898150509964927,0.4999611899716947
3,158
Amino acid transmembrane transporter activity
9
12
1.963406
0.049599
Q15758,Q96NB2,Q9H936,P30825,Q9H9B4,Q9UPY5,P08195,Q9UJS0,O75746
Functions
GO Molecular function
msigdb_gomf
416,322,619,387,557,298,461,801,469
469,461,387,416,322,1287,850,619,557,801,298,1262
0.7822020382068811,0.8005763108055255,0.9456831946575108,0.8916563244233383,1.1050658553906163,0.061498752291908376,0.3637731497479283,0.5764726853733471,0.6520630652256373,0.40298796762993605,1.174645451401165,0.08211600805520915
3,158
Abnormal epiphyseal ossification
9
15
1.960613
0.049924
O00116,Q14739,P08236,P38435,Q96HY6,O75381,P40855,Q15738,Q96L58
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
224,253,235,205,465,113,398,181,218
224,2395,113,235,2085,205,398,253,1454,181,532,465,218,1260,722
1.4290524817880874,-0.5458927047153141,2.062404795850602,1.3789687523304992,-0.3660890405758847,1.5116725479401998,0.9277252404864844,1.3284931338845052,-0.04263501903286422,1.6577864035634409,0.6895204380991842,0.8005763108055255,1.4622272217645225,0.08211600805520915,0.48068645890860423
3,158
Transporter activity
46
161
4.772788
0.000002
P13073,Q9BSK2,Q9H2V7,Q96ES6,O95202,O60830,Q8WTV0,Q9Y487,Q8TAD4,O43772,Q9NS69,P08183,Q7Z3C6,P21796,P04062,Q99595,Q9H2D1,Q14849,P45880,P51798,O14925,Q9UM00,Q8IXU6,Q7L0J3,Q9BQT8,Q9UDW1,Q7KZN9,Q6N075,Q9Y619,O43676,O00299,Q15388,Q9H936,O75964,P53985,O15118,Q03518,Q70HW3,Q9C0H2,Q9Y6M7,P30536,Q9HC21,Q9P0J0,P41440,Q9UBX3,Q9Y277
Functions
GO Molecular function
msigdb_gomf
253,255,271,12,262,17,18,153,280,23,24,147,278,26,158,32,35,294,38,291,169,310,48,53,56,59,192,328,72,73,198,205,78,81,82,208,87,88,94,102,100,112,249,243,259,260
1715,592,198,1762,1763,169,208,435,73,624,23,874,17,673,1344,526,323,1912,1160,2613,81,2728,1385,2935,262,3055,1388,959,158,2991,2644,1161,1962,1864,2969,147,2061,651,2396,2115,2695,527,751,253,1821,350,3096,2647,1166,3009,2649,26,2318,554,2779,752,1968,100,1866,1259,1723,1208,1091,2959,243,38,1093,2701,1262,1495,3182,1869,291,722,2168,2999,1630,82,1211,1827,1355,2554,2074,1131,3026,1733,1687,479,87,458,1640,1102,1177,294,1504,205,1835,2440,1325,328,2290,1643,2026,1589,88,192,53,278,48,2092,1796,2599,280,638,824,18,1113,793,12,2411,1372,1187,2572,32,831,664,2919,56,255,3059,698,1232,2767,94,2768,35,1852,271,78,1234,469,112,483,2873,24,1290,249,259,59,867,1710,1025,310,391,260,153,2393,72,987,102,1240
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3,193