term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Predicted secreted proteins | 25 | 60 | 3.177866 | 0.001484 | Q15165,Q92520,P05067,P80303,Q9UM22,Q6P179,Q9Y287,Q8NBM8,P07858,Q02818,Q99584,P84157,P43490,Q9HB40,P26583,P04083,Q9NZ08,O75718,O75629,O00584,P14174,P22413,O60888,Q9Y4P3,Q07021 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 131,267,513,13,405,16,414,284,281,159,425,421,46,51,438,190,191,454,327,326,80,472,115,512,378 | 326,1855,115,327,454,2025,926,3134,190,647,513,2110,3076,281,3166,1114,80,1228,3339,2944,472,2504,438,46,1498,2379,1809,2981,13,421,159,378,1524,1914,2174,2122,131,16,2558,1003,284,3350,1333,1924,267,2287,425,2933,722,531,1931,1264,51,191,1794,2660,405,3381,414,512 | 1.233951351838413,-0.21393665194747497,2.046646024024901,1.233951351838413,0.961070082526128,-0.30611409685763147,0.37472066384711566,-1.0606389558982219,1.6299606471660821,0.6846286512595186,0.8741659228684505,-0.3523723803792923,-0.9965341580527574,1.3336236238545365,-1.0927799665620832,0.22545709717825904,2.455983823206309,0.13535733730271166,-1.8662601339900915,-0.8690218779880967,0.9321417422805507,-0.5541621697421181,1.0043887198247081,2.9779167973527434,-0.015734964198557747,-0.47629050319229616,-0.18331016512462858,-0.900813798450678,3.8500550386939207,1.0476193288474605,1.7975494659955786,1.1194765902923671,-0.030908945292574343,-0.24461259530598548,-0.3832747697389823,-0.3523723803792923,1.9224351248878877,3.7217303548789196,-0.5854034026110678,0.3300585863237035,1.3336236238545365,-2.0697868950068465,0.07506070309973252,-0.24461259530598548,1.3762015415441697,-0.4297244698805092,1.0476193288474605,-0.8531472312752075,0.5818477409079303,0.8596469929949846,-0.24461259530598548,0.12030055776561276,2.8051701921988266,1.6299606471660821,-0.1680153718164889,-0.6480464817522166,1.0763911704719784,-3.713117064501521,1.062010089223635,0.888674836109678 | 3,392 |
Vascular skin abnormality | 34 | 124 | 3.167363 | 0.001538 | Q96MW5,Q99643,P10644,Q06136,Q8NCH0,P31749,P51648,P53701,P07858,P04062,P00846,P10619,P04066,Q13126,O75306,P35670,O75844,P40763,Q15427,Q9BUR4,P38435,Q14108,P21359,Q9NWM8,P03886,Q8IZA0,P36543,P00403,Q9H9E3,P22413,P22830,Q08J23,Q9Y487,Q99829 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 403,530,397,147,22,23,27,411,281,32,33,35,418,43,417,430,50,307,434,182,444,74,204,340,220,355,473,92,356,472,483,361,235,374 | 1182,1675,2456,3380,2367,1855,1879,2732,2621,417,1758,50,1759,2967,2306,92,33,1022,844,220,32,418,601,3015,281,2083,35,397,1489,3203,2968,1144,2787,1732,1943,2923,204,1909,709,472,483,3189,877,2063,1438,23,2735,1595,1372,430,473,2698,444,2236,307,858,694,3289,2198,1912,1271,27,1406,3292,411,2971,1706,2649,2579,1862,2835,861,2604,2006,147,1810,3136,361,43,74,1917,1133,3020,2722,2533,434,2753,3041,2485,1578,960,3268,1445,2890,2893,1468,542,355,1385,22,1992,1745,2512,1532,403,3099,2957,530,374,182,826,655,1286,1038,356,917,340,1106,2784,1456,2939,1798,235,1566 | 0.16543634416126807,-0.12220433600304552,-0.522974005179062,-3.560386229094952,-0.47629050319229616,-0.21393665194747497,-0.22926842223566576,-0.710906100634738,-0.6323655241400963,1.0476193288474605,-0.1680153718164889,2.8318251529978857,-0.1680153718164889,-0.8849107173056833,-0.44523349939724377,2.2930986183056987,3.2806564295146425,0.3002284258115414,0.4489377993753778,1.5175365324543044,3.2937373551059523,1.0476193288474605,0.7431317115189636,-0.9326628846066711,1.3336236238545365,-0.3369402862428846,3.2151509431473015,1.0763911704719784,-0.015734964198557747,-1.1572413371765422,-0.8849107173056833,0.1954695077304166,-0.7581946761452075,-0.15273282774028654,-0.25996921007055324,-0.8531472312752075,1.573819316272094,-0.24461259530598548,0.596562227640058,0.9321417422805507,0.9176627193149094,-1.1249806168260381,0.4192837063531287,-0.32152087180770866,0.014577395414097777,3.502130832268083,-0.710906100634738,-0.07650252744056436,0.044842523349634685,1.0332188640882995,0.9321417422805507,-0.6794490424983824,0.989958989232039,-0.4142283661153823,1.2767238749913556,0.4341161923697676,0.6112661660954188,-1.4667998334603056,-0.3987451465185144,-0.24461259530598548,0.10523221520582753,3.4501901747304498,0.0297158455536117,-1.483251123536119,1.062010089223635,-0.8849107173056833,-0.13746249502499586,-0.6480464817522166,-0.6010440292225467,-0.21393665194747497,-0.7897895963070047,0.4341161923697676,-0.6166980548909288,-0.2907199213981397,1.839253870725676,-0.18331016512462858,-1.0606389558982219,1.162475796263921,3.017611640595729,2.5370126379799847,-0.24461259530598548,0.21046898250401078,-0.9326628846066711,-0.6951707365076549,-0.5697761307887955,1.018808669576008,-0.726655180985889,-0.9486089895638056,-0.5385614757094254,-0.06129269053099454,0.3598443506231174,-1.3684308687904816,0.014577395414097777,-0.8214403202477919,-0.8214403202477919,-0.00057286259791032,0.8451180196791206,1.1910943651123755,0.044842523349634685,3.553967705609741,-0.2753383056546045,-0.15273282774028654,-0.5541621697421181,-0.030908945292574343,1.0763911704719784,-1.0125383355924664,-0.8690218779880967,0.8596469929949846,1.1338192053070948,1.657978695449809,0.47854849943901234,0.6846286512595186,0.10523221520582753,0.3002284258115414,1.1910943651123755,0.38958597328502204,1.2196751063114128,0.24043388497129026,-0.7424180239388641,0.014577395414097777,-0.8531472312752075,-0.1680153718164889,1.4893416625418183,-0.04609484197467206 | 3,392 |
Signaling by hedgehog | 15 | 60 | 3.166105 | 0.001545 | Q9BUF5,Q9Y496,Q9UL46,O00231,P28072,P28070,Q9UBV2,P04350,P49721,P20618,P10644,P61289,Q06323,Q2M1P5,P49720 | Processes and pathways | Reactome Pathways | msigdb_reactome | 426,129,64,193,164,227,335,482,75,236,397,116,121,354,445 | 193,3012,1878,872,1621,1396,1701,482,1113,397,1115,2787,1230,236,929,1231,1832,1659,2168,227,164,1145,1254,1805,759,2169,1298,445,75,1211,1299,1461,1096,116,889,2141,1836,1837,696,121,2007,1275,1684,2720,503,2888,1353,354,2628,1306,2794,1692,825,1962,426,335,64,1390,1697,129 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.9176627193149094,0.22545709717825904,1.0763911704719784,0.22545709717825904,-0.7581946761452075,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,0.12030055776561276,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.09015227518848501,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,-0.00057286259791032,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,0.6112661660954188,2.0191011953082207,-0.2907199213981397,0.10523221520582753,-0.12220433600304552,-0.6951707365076549,0.888674836109678,-0.8214403202477919,0.0599574641453926,1.1910943651123755,-0.6323655241400963,0.09015227518848501,-0.7581946761452075,-0.12220433600304552,0.47854849943901234,-0.25996921007055324,1.0476193288474605,1.233951351838413,2.671459958677549,0.044842523349634685,-0.12220433600304552,1.936269398935176 | 3,392 |
Intra golgi and retrograde golgi to er traffic | 36 | 103 | 3.154145 | 0.00161 | Q9Y496,Q15363,Q6NUQ1,Q96MW5,Q13561,O00461,O43731,Q07866,P24390,Q9BUF5,Q13190,O14653,O60333,Q8TBA6,P49755,P68371,Q8TD16,O15260,O75935,Q10472,P33176,Q9NSK0,P84085,P39880,O95721,Q9UJW0,Q12981,Q9H9E3,P68402,O43752,P04350,Q13885,Q14203,O14579,Q9Y3B3,Q9P2W9 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,386,519,403,650,276,149,661,28,426,165,289,169,172,565,696,63,65,197,450,455,72,586,595,593,86,717,356,350,225,482,503,491,252,124,125 | 1726,2364,276,252,289,65,971,2265,1936,2058,149,225,169,2476,2060,197,3103,874,772,593,482,3122,1433,3150,28,455,1169,595,2548,1374,2506,2480,1297,1325,565,2378,1889,3340,2527,2379,1707,801,1680,890,1326,696,350,1948,1237,586,661,1098,450,2121,717,165,1662,650,503,491,3180,2679,1134,789,386,1604,960,733,519,2511,1384,2127,1717,2708,172,63,1531,1785,1336,403,3098,2074,1035,426,1418,1419,1748,1900,1643,356,2052,2397,72,1423,125,1751,2131,86,968,124,129,3144,1799 | -0.15273282774028654,-0.47629050319229616,1.3478254524900601,1.4186970981267617,1.3194125750424903,2.644629964151358,0.3449570020292946,-0.4297244698805092,-0.25996921007055324,-0.32152087180770866,1.8253608767518077,1.5034435722199273,1.71391040052824,-0.5385614757094254,-0.32152087180770866,1.6019075774365181,-1.0285571596923793,0.4192837063531287,0.5228837222779321,0.7577317502408601,0.9176627193149094,-1.0445906823532496,0.014577395414097777,-1.0767020329756654,3.4241806746156223,0.961070082526128,0.18045863946931265,0.7577317502408601,-0.5854034026110678,0.044842523349634685,-0.5541621697421181,-0.5385614757094254,0.09015227518848501,0.07506070309973252,0.8014705690921952,-0.47629050319229616,-0.22926842223566576,-1.8662601339900915,-0.5697761307887955,-0.47629050319229616,-0.13746249502499586,0.4933376536617622,-0.12220433600304552,0.4044403103634737,0.07506070309973252,0.6112661660954188,1.1910943651123755,-0.25996921007055324,0.13535733730271166,0.7723215542957492,0.6699770190108111,0.24043388497129026,0.9755194520783873,-0.3523723803792923,0.5818477409079303,1.741824390244023,-0.1069583132087397,0.6846286512595186,0.888674836109678,0.9031737594044319,-1.1088728099650214,-0.6637409727699075,0.21046898250401078,0.5081160512050436,1.1051243960353279,-0.07650252744056436,0.3598443506231174,0.5671226765594547,0.8741659228684505,-0.5541621697421181,0.044842523349634685,-0.3523723803792923,-0.13746249502499586,-0.6794490424983824,1.71391040052824,2.671459958677549,-0.030908945292574343,-0.1680153718164889,0.07506070309973252,1.0763911704719784,-1.0125383355924664,-0.32152087180770866,0.3002284258115414,1.0476193288474605,0.0297158455536117,0.0297158455536117,-0.15273282774028654,-0.22926842223566576,-0.09172438937674851,1.1910943651123755,-0.30611409685763147,-0.47629050319229616,2.5774251672985713,0.0297158455536117,1.977722435244023,-0.15273282774028654,-0.3523723803792923,2.4153666489525016,0.3598443506231174,1.9915235827542386,1.936269398935176,-1.0606389558982219,-0.1680153718164889 | 3,392 |
Calcium-binding protein | 11 | 21 | 3.14092 | 0.001684 | Q02818,Q99584,Q14257,Q9BRK5,P80303,P43307,P14649,P41208,Q8N163,O43852,P60660 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 159,425,99,135,13,49,54,278,279,151,119 | 151,2543,54,3189,1946,278,49,119,1522,13,159,99,1919,2891,2813,485,279,425,2289,135,2056 | 1.8114594151764092,-0.5854034026110678,2.725031627796951,-1.1249806168260381,-0.25996921007055324,1.3478254524900601,2.8451418463357636,2.0191011953082207,-0.030908945292574343,3.8500550386939207,1.7975494659955786,2.224898571271148,-0.24461259530598548,-0.8214403202477919,-0.7739851845325647,0.9176627193149094,1.3478254524900601,1.0476193288474605,-0.4297244698805092,1.9085925209979264,-0.30611409685763147 | 3,392 |
Signaling by the b cell receptor bcr | 10 | 46 | 3.135889 | 0.001713 | Q9UL46,O00231,P28072,O43865,P28070,Q08209,P49721,P20618,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,290,227,232,75,236,116,121 | 193,3012,1878,872,1621,312,1396,290,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,819,1554,1837,121,232,2007,1684,2888,1353,2794,825,1962,64,1390,1697 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,1.262475712405316,0.0297158455536117,1.3194125750424903,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,0.47854849943901234,-0.04609484197467206,-0.19861724574074396,2.0191011953082207,1.4893416625418183,-0.2907199213981397,-0.12220433600304552,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,-0.12220433600304552 | 3,392 |
Anion transmembrane transport | 12 | 46 | 3.134721 | 0.00172 | P51797,P21796,Q9UHG3,P08195,Q9BQT8,P45880,Q15041,Q9H2D1,Q9Y619,Q9UBX3,O43808,Q14728 | Processes and pathways | GO Biological process | msigdb_gobp | 228,69,90,71,393,102,248,15,87,26,219,475 | 2333,219,572,2439,1430,1623,1976,2571,2457,928,71,997,1549,69,1551,2905,102,1679,228,1406,2648,2005,1256,2120,1681,1661,475,248,2386,3264,508,2352,1083,393,15,991,1104,2473,810,26,90,1342,1905,1587,87,1567 | -0.46075549648323305,1.5175365324543044,0.7869011513881382,-0.5073997148873077,0.014577395414097777,-0.09172438937674851,-0.2753383056546045,-0.6010440292225467,-0.522974005179062,0.37472066384711566,2.5774251672985713,0.3300585863237035,-0.04609484197467206,2.6043294186857167,-0.04609484197467206,-0.8372867282398355,2.197563227073385,-0.12220433600304552,1.5034435722199273,0.0297158455536117,-0.6480464817522166,-0.2907199213981397,0.12030055776561276,-0.3523723803792923,-0.12220433600304552,-0.1069583132087397,0.9321417422805507,1.4328440873723212,-0.47629050319229616,-1.352091936483502,0.888674836109678,-0.46075549648323305,0.2553993789324403,1.0907625977334081,3.760293155258865,0.3449570020292946,0.24043388497129026,-0.522974005179062,0.4933376536617622,3.476173526807814,2.320323681373693,0.07506070309973252,-0.22926842223566576,-0.06129269053099454,2.4018122550596814,-0.04609484197467206 | 3,392 |
Intracellular calcium-sensing protein | 10 | 18 | 3.132327 | 0.001734 | Q02818,Q99584,Q14257,Q9BRK5,P80303,P41208,P14649,O43852,P60660,Q8N163 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 159,425,99,135,13,278,54,151,119,279 | 151,2543,54,1946,278,119,1522,13,159,99,1919,2891,2813,485,279,425,2289,135 | 1.8114594151764092,-0.5854034026110678,2.725031627796951,-0.25996921007055324,1.3478254524900601,2.0191011953082207,-0.030908945292574343,3.8500550386939207,1.7975494659955786,2.224898571271148,-0.24461259530598548,-0.8214403202477919,-0.7739851845325647,0.9176627193149094,1.3478254524900601,1.0476193288474605,-0.4297244698805092,1.9085925209979264 | 3,392 |
Calmodulin | 10 | 18 | 3.132327 | 0.001734 | Q02818,Q99584,Q14257,Q9BRK5,P80303,P41208,P14649,O43852,P60660,Q8N163 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 159,425,99,135,13,278,54,151,119,279 | 151,2543,54,1946,278,119,1522,13,159,99,1919,2891,2813,485,279,425,2289,135 | 1.8114594151764092,-0.5854034026110678,2.725031627796951,-0.25996921007055324,1.3478254524900601,2.0191011953082207,-0.030908945292574343,3.8500550386939207,1.7975494659955786,2.224898571271148,-0.24461259530598548,-0.8214403202477919,-0.7739851845325647,0.9176627193149094,1.3478254524900601,1.0476193288474605,-0.4297244698805092,1.9085925209979264 | 3,392 |
Phenotypic variability | 40 | 108 | 3.122119 | 0.001796 | P46976,P00374,Q13510,Q9H061,O43707,P42224,Q6UWE0,P17900,Q13813,Q9BUF5,P00846,Q9UEY8,O60333,Q70HW3,O14979,Q9BV79,P35270,Q8WWY3,P07196,Q15427,Q8WVQ1,Q8TD16,Q6P4A7,Q14671,O60313,P23258,P09622,Q9Y4W6,P03886,P00403,P04350,P06753,Q9NZJ7,Q9NR77,Q13868,P07602,Q9Y263,Q13885,Q8NI60,P36551 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 258,4,132,12,771,788,792,146,663,426,33,688,169,44,557,48,560,682,178,434,322,63,196,457,707,582,594,739,220,92,482,610,631,108,622,117,644,503,640,377 | 2191,2877,1828,1485,557,1367,771,707,169,1879,1729,2336,2306,1269,4,92,33,844,220,482,610,178,117,2768,2133,2026,594,3378,146,1909,582,905,1595,560,377,2404,2236,1059,3282,788,1374,886,258,1376,1011,2003,1912,1405,2199,1889,953,2343,1461,2088,1378,2575,2281,2701,1599,983,2121,132,663,622,503,457,2008,2722,434,1813,1814,1986,2706,196,3043,792,44,640,1386,63,322,682,894,1960,895,426,48,12,809,2185,1264,2294,108,900,2078,2900,3314,631,1180,1752,688,2223,644,1826,1969,1798,739,994 | -0.3987451465185144,-0.8214403202477919,-0.19861724574074396,-0.015734964198557747,0.8160298348526115,0.044842523349634685,0.5228837222779321,0.596562227640058,1.71391040052824,-0.22926842223566576,-0.15273282774028654,-0.46075549648323305,-0.44523349939724377,0.10523221520582753,4.25660783544249,2.2930986183056987,3.2806564295146425,0.4489377993753778,1.5175365324543044,0.9176627193149094,0.7285214102943242,1.6859618908518097,2.0328776982252563,-0.7424180239388641,-0.3678171946564402,-0.30611409685763147,0.7577317502408601,-3.3346573519697245,1.8531384170199579,-0.24461259530598548,0.7723215542957492,0.38958597328502204,-0.07650252744056436,0.8160298348526115,1.1194765902923671,-0.4918385618163464,-0.4142283661153823,0.2703536119434672,-1.4339458950700101,0.5081160512050436,0.044842523349634685,0.4044403103634737,1.3903758478681065,0.044842523349634685,0.31514907160504646,-0.2907199213981397,-0.24461259530598548,0.0297158455536117,-0.3987451465185144,-0.22926842223566576,0.3598443506231174,-0.46075549648323305,-0.00057286259791032,-0.3369402862428846,0.044842523349634685,-0.6010440292225467,-0.4297244698805092,-0.6794490424983824,-0.07650252744056436,0.3449570020292946,-0.3523723803792923,1.9085925209979264,0.6699770190108111,0.7139008185990915,0.888674836109678,0.961070082526128,-0.2907199213981397,-0.6951707365076549,1.018808669576008,-0.18331016512462858,-0.18331016512462858,-0.2753383056546045,-0.6794490424983824,1.6159385005727454,-0.9486089895638056,0.5081160512050436,3.0043870268143222,0.6992699083324146,0.044842523349634685,2.671459958677549,1.2482182125944992,0.6259595854721536,0.4044403103634737,-0.25996921007055324,0.4044403103634737,1.0476193288474605,2.858451368283087,3.8628534229832154,0.4933376536617622,-0.3832747697389823,0.12030055776561276,-0.4297244698805092,2.1153656498312228,0.4044403103634737,-0.32152087180770866,-0.8214403202477919,-1.6154534426268758,0.7139008185990915,0.18045863946931265,-0.15273282774028654,0.6259595854721536,-0.3987451465185144,0.6992699083324146,-0.18331016512462858,-0.25996921007055324,-0.1680153718164889,0.5671226765594547,0.3449570020292946 | 3,392 |
Cytoprotection by hmox1 | 16 | 69 | 3.113921 | 0.001846 | Q9UL46,O00231,P28072,Q8N8Q8,Q86X55,P28070,P20674,P09601,P49721,P20618,P40763,P30519,P61289,Q06323,P49720,P00403 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,291,68,227,358,10,75,236,307,20,116,121,445,92 | 193,3012,1878,2903,872,852,1621,1396,2304,3014,1701,462,92,10,2307,2196,876,1656,1230,949,236,358,929,1231,1832,1659,2168,227,164,1145,20,1805,307,2672,759,2169,445,75,1211,679,1299,1096,116,889,2141,1836,1837,1379,2604,121,2007,1684,2720,2384,2888,1353,2040,68,291,3129,2794,1219,1312,825,1962,655,64,1390,1108 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,-0.8372867282398355,0.4192837063531287,0.4341161923697676,-0.09172438937674851,0.0297158455536117,-0.44523349939724377,-0.9326628846066711,-0.13746249502499586,0.9466108546188425,2.2930986183056987,3.9012117159107698,-0.44523349939724377,-0.3987451465185144,0.4192837063531287,-0.1069583132087397,0.13535733730271166,0.3598443506231174,1.4752307813901213,1.1767898212573111,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,3.5669108013937043,-0.18331016512462858,1.2767238749913556,-0.6637409727699075,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.6259595854721536,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,0.044842523349634685,-0.6166980548909288,2.0191011953082207,-0.2907199213981397,-0.12220433600304552,-0.6951707365076549,-0.47629050319229616,-0.8214403202477919,0.0599574641453926,-0.30611409685763147,2.6177703621148702,1.3194125750424903,-1.0445906823532496,-0.7581946761452075,0.1504025880743201,0.09015227518848501,0.47854849943901234,-0.25996921007055324,0.6846286512595186,2.671459958677549,0.044842523349634685,0.24043388497129026 | 3,392 |
Protein localization | 27 | 76 | 3.113394 | 0.001849 | Q9Y5Y5,Q99595,Q9Y5J9,O60830,P09601,P05067,O43681,P51648,Q13505,O75381,Q13190,Q9NS69,O43615,P46379,P21796,Q9Y3D6,Q10713,P56589,P06576,Q15388,O43808,P40855,O14734,O14925,Q9NR77,Q9Y512,Q8N4H5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 130,6,268,9,10,513,523,27,31,280,165,42,66,319,69,469,83,464,214,342,219,93,471,346,108,365,245 | 2057,471,346,1727,1226,66,523,545,219,9,280,3075,692,1857,3277,2439,3270,1702,1624,513,214,1185,3305,10,2028,997,1549,1228,69,1804,2644,2233,2624,2671,93,319,978,1272,27,1835,464,2067,3348,83,3053,165,31,664,342,2244,747,636,3379,2583,245,1783,2251,6,2656,964,3260,2936,108,42,868,1793,2849,1342,2590,1826,812,469,365,3101,268,130 | -0.32152087180770866,0.9321417422805507,1.1910943651123755,-0.15273282774028654,0.13535733730271166,2.644629964151358,0.8596469929949846,0.8305789759854734,1.5175365324543044,3.9522705239894336,1.3336236238545365,-0.9965341580527574,0.6112661660954188,-0.21393665194747497,-1.4175431235378706,-0.5073997148873077,-1.3847856707979227,-0.13746249502499586,-0.09172438937674851,0.8741659228684505,1.5316205651807586,0.16543634416126807,-1.5657532843548536,3.9012117159107698,-0.30611409685763147,0.3300585863237035,-0.04609484197467206,0.13535733730271166,2.6043294186857167,-0.18331016512462858,-0.6480464817522166,-0.4142283661153823,-0.6323655241400963,-0.6637409727699075,2.2930986183056987,1.2482182125944992,0.3449570020292946,0.10523221520582753,3.4501901747304498,-0.19861724574074396,0.9466108546188425,-0.32152087180770866,-2.035681723950639,2.428913363747869,-0.9645695362458719,1.741824390244023,3.359041854851364,0.6699770190108111,1.205389452082045,-0.4142283661153823,0.5523870051126312,0.6992699083324146,-3.4094648282561173,-0.6010440292225467,1.4469820160729245,-0.1680153718164889,-0.4142283661153823,4.1048668927725505,-0.6480464817522166,0.3598443506231174,-1.3357688144594548,-0.8531472312752075,2.1153656498312228,3.0704404222415245,0.4341161923697676,-0.1680153718164889,-0.7897895963070047,0.07506070309973252,-0.6010440292225467,-0.18331016512462858,0.4933376536617622,0.9466108546188425,1.162475796263921,-1.0125383355924664,1.3762015415441697,1.936269398935176 | 3,392 |
Abnormal tissue metabolite concentration | 10 | 16 | 3.101801 | 0.001923 | O75381,P06280,Q9Y5Y5,Q9NZJ7,O43681,P17900,P56589,P07602,P06865,P40855 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 280,601,130,631,523,146,464,117,215,93 | 523,280,601,215,117,2269,146,93,1272,1835,464,636,1841,631,1826,130 | 0.8596469929949846,1.3336236238545365,0.7431317115189636,1.5316205651807586,2.0328776982252563,-0.4297244698805092,1.8531384170199579,2.2930986183056987,0.10523221520582753,-0.19861724574074396,0.9466108546188425,0.6992699083324146,-0.19861724574074396,0.7139008185990915,-0.18331016512462858,1.936269398935176 | 3,392 |
Mapk6 mapk4 signaling | 9 | 48 | 3.087759 | 0.002017 | Q9UL46,O00231,Q9HCE1,P28072,P28070,P49721,P61289,Q06323,Q16181 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,230,164,227,75,116,121,126 | 193,3012,1878,872,1621,2303,1396,1701,796,2787,1230,236,1435,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,1573,116,889,2141,1836,2142,121,1274,2007,2888,1353,126,2794,825,1962,230,1220,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,-0.44523349939724377,0.0297158455536117,-0.13746249502499586,0.4933376536617622,-0.7581946761452075,0.13535733730271166,1.4752307813901213,0.014577395414097777,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,-0.06129269053099454,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.3678171946564402,2.0191011953082207,0.10523221520582753,-0.2907199213981397,-0.8214403202477919,0.0599574641453926,1.9639130348690015,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,1.5034435722199273,0.1504025880743201,2.671459958677549,0.044842523349634685 | 3,392 |
Abc family proteins mediated transport | 12 | 53 | 3.081931 | 0.002057 | Q9UL46,O00231,P28072,P28070,O75027,Q9UBV2,P49721,P20618,P61289,Q06323,P49720,P40855 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,39,335,75,236,116,121,445,93 | 193,3012,1878,872,1621,2333,1396,39,1701,1593,1625,928,1230,2546,236,929,1231,1832,1659,2168,227,164,1145,2233,1805,93,759,2169,445,75,1211,1299,1461,464,1096,116,889,2141,1836,121,2007,1275,2888,1353,2286,2794,825,1962,654,2741,335,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,-0.46075549648323305,0.0297158455536117,3.136320692524441,-0.13746249502499586,-0.07650252744056436,-0.09172438937674851,0.37472066384711566,0.13535733730271166,-0.5854034026110678,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.4142283661153823,-0.18331016512462858,2.2930986183056987,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,-0.00057286259791032,0.9466108546188425,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,0.10523221520582753,-0.8214403202477919,0.0599574641453926,-0.4297244698805092,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,0.6846286512595186,-0.710906100634738,1.233951351838413,2.671459958677549,0.044842523349634685 | 3,392 |
Golgi cisterna | 11 | 31 | 3.075931 | 0.002098 | Q11206,Q15363,Q9Y3A3,Q8NBZ7,Q8TBA6,Q8NBN3,Q10713,O00461,Q08378,Q8WVQ1,Q9Y6B6 | Localization | GO Cellular component | msigdb_gocc | 353,386,98,134,172,113,83,276,352,322,158 | 276,1568,618,772,2372,2135,948,3238,2579,352,1682,1098,450,83,353,2530,2242,386,1604,113,134,172,1414,322,1336,989,1200,869,1515,98,158 | 1.3478254524900601,-0.06129269053099454,0.7139008185990915,0.5228837222779321,-0.47629050319229616,-0.3678171946564402,0.3598443506231174,-1.2706332542898442,-0.6010440292225467,1.1910943651123755,-0.12220433600304552,0.24043388497129026,0.9755194520783873,2.428913363747869,1.1910943651123755,-0.5697761307887955,-0.4142283661153823,1.1051243960353279,-0.07650252744056436,2.074158219188792,1.9085925209979264,1.71391040052824,0.0297158455536117,1.2482182125944992,0.07506070309973252,0.3449570020292946,0.16543634416126807,0.4341161923697676,-0.015734964198557747,2.2522022302138622,1.8114594151764092 | 3,392 |
Ion transport | 62 | 221 | 3.075693 | 0.0021 | O15173,Q9BQT8,P05067,Q8N4V1,Q9H2D1,O43681,P61421,P31749,P47985,Q9UBX3,P62258,P00846,Q13555,O43865,O75027,P24941,Q70HW3,Q9HD20,P35670,Q6KCM7,O75844,Q96GC9,P04083,O60831,Q6P4A7,P21796,P08195,P33176,Q13423,O75964,P21359,Q7KZN9,Q9UNH7,Q9NWR8,P14174,P11413,Q9UDW1,P24539,Q9Y619,P06576,Q9UHG3,O43808,Q9C0H2,Q14728,P36543,P00403,Q04917,P51797,P22413,Q8IYU8,P45880,P20674,Q08209,Q08722,Q8TAD4,Q8NEW0,Q8TB61,P07602,Q9H813,Q15041,Q9H4I9,P27105 | Processes and pathways | GO Biological process | msigdb_gobp | 1,393,513,529,15,523,526,23,537,26,283,33,34,290,39,547,44,176,430,562,50,186,190,572,196,69,71,455,588,73,204,329,461,207,80,337,82,463,87,214,90,219,95,475,473,92,474,228,472,485,102,358,232,490,110,109,508,117,381,248,380,376 | 2962,2434,1828,2903,852,1485,1250,1,2333,523,771,2663,219,290,1972,572,39,2639,2569,996,2368,1857,2439,50,1430,784,73,1518,1253,1623,1624,92,33,3134,190,2373,1976,1730,2229,513,2571,2457,214,2502,3076,1431,117,1432,928,71,1185,2135,2543,2196,3378,2803,337,997,1549,876,1370,80,2231,1116,2787,3204,1658,358,950,3347,2923,204,69,472,1118,463,547,2644,376,1295,1628,2233,1979,2458,775,786,1551,23,1980,455,1595,430,2403,1860,473,2236,2905,102,2506,585,2139,537,3035,878,1679,228,1406,1888,2648,2005,2481,2979,1256,979,2237,1982,954,526,2140,2834,283,819,2314,3178,2120,2579,1681,1770,2701,908,1661,861,474,983,2446,232,490,3221,1302,933,588,34,1352,475,248,1134,2242,2386,2534,562,1445,2890,196,863,3264,44,329,961,2285,485,2684,529,1413,1360,1687,109,110,508,2352,1719,1472,2179,749,2779,186,2217,1083,1244,2762,1788,1928,2289,393,3069,95,1748,2492,15,702,2614,380,381,991,1104,1020,2473,176,810,2424,867,2427,207,631,26,82,1481,90,2298,2398,1342,1999,2299,2329,1723,461,1905,2056,1587,739,87,1567 | 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| 3,392 |
Cognitive impairment | 52 | 177 | 3.072632 | 0.002122 | Q9Y5Y5,Q9BQE5,Q13510,P05067,P35637,Q99643,O43681,Q6DKK2,P17900,P10644,P31749,Q9Y287,P54802,Q9H6K4,O95831,P04062,P00846,O75381,O75306,P35670,P35270,Q7LG56,P07196,P50897,Q9Y4U1,Q9NZ08,Q5XKP0,Q14108,O43464,P21359,P22626,Q10713,P56589,Q9Y619,P06865,O95319,P03886,P40855,P00403,P06280,P36543,Q08209,P04350,Q9NZJ7,Q9Y487,Q14203,Q05639,P07602,Q9NWW5,Q9Y263,Q9NPL8,Q5JTZ9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 130,7,132,513,263,530,523,144,146,397,23,414,154,156,30,32,33,280,417,430,560,174,178,55,325,191,200,74,203,204,328,83,464,87,215,600,220,93,92,601,473,232,482,631,235,491,620,117,118,644,643,505 | 1828,2132,1457,203,523,2304,707,1346,417,280,632,693,2336,600,1269,30,1624,92,33,1022,220,32,1975,482,1939,513,601,215,178,117,2269,1940,1209,2026,1227,3149,397,3378,997,3123,1144,1657,146,1732,1943,1057,2923,204,1909,709,2696,328,1733,1762,1493,2309,1040,23,560,263,430,473,2236,93,2002,2672,886,1235,2377,2198,1376,887,1272,55,2885,3197,1835,2199,953,1094,154,1706,1461,464,1378,800,2834,1809,1131,2701,1381,2529,3220,982,3153,620,983,232,83,934,1328,1213,2202,132,74,491,1149,1917,1897,2241,2556,2605,505,1986,200,144,3297,2175,3043,985,2754,174,2125,2467,2563,1279,2319,1959,2357,1960,895,3372,3243,2288,1961,1284,2218,1787,2762,530,2536,1034,7,1615,1261,1263,156,1264,643,867,1388,2017,900,2078,2918,118,191,631,1180,1874,688,2155,1342,1875,1456,2938,2992,644,414,1248,3073,235,325,739,994,130,87 | -0.19861724574074396,-0.3678171946564402,-0.00057286259791032,1.573819316272094,0.8596469929949846,-0.44523349939724377,0.596562227640058,0.0599574641453926,1.0476193288474605,1.3336236238545365,0.6992699083324146,0.6112661660954188,-0.46075549648323305,0.7431317115189636,0.10523221520582753,3.37208282113663,-0.09172438937674851,2.2930986183056987,3.2806564295146425,0.3002284258115414,1.5175365324543044,3.2937373551059523,-0.2753383056546045,0.9176627193149094,-0.25996921007055324,0.8741659228684505,0.7431317115189636,1.5316205651807586,1.6859618908518097,2.0328776982252563,-0.4297244698805092,-0.25996921007055324,0.1504025880743201,-0.30611409685763147,0.13535733730271166,-1.0767020329756654,1.0763911704719784,-3.3346573519697245,0.3300585863237035,-1.0445906823532496,0.1954695077304166,-0.1069583132087397,1.8531384170199579,-0.15273282774028654,-0.25996921007055324,0.2703536119434672,-0.8531472312752075,1.573819316272094,-0.24461259530598548,0.596562227640058,-0.6794490424983824,1.233951351838413,-0.15273282774028654,-0.1680153718164889,-0.015734964198557747,-0.44523349939724377,0.2852966167197613,3.502130832268083,0.8160298348526115,1.3762015415441697,1.0332188640882995,0.9321417422805507,-0.4142283661153823,2.2930986183056987,-0.2907199213981397,-0.6637409727699075,0.4044403103634737,0.13535733730271166,-0.47629050319229616,-0.3987451465185144,0.044842523349634685,0.4044403103634737,0.10523221520582753,2.725031627796951,-0.8214403202477919,-1.141103441123685,-0.19861724574074396,-0.3987451465185144,0.3598443506231174,0.24043388497129026,1.8114594151764092,-0.13746249502499586,-0.00057286259791032,0.9466108546188425,0.044842523349634685,0.4933376536617622,-0.7897895963070047,-0.18331016512462858,0.21046898250401078,-0.6794490424983824,0.044842523349634685,-0.5697761307887955,-1.2057460042171027,0.3449570020292946,-1.0767020329756654,0.7139008185990915,0.3449570020292946,1.4893416625418183,2.428913363747869,0.37472066384711566,0.07506070309973252,0.1504025880743201,-0.3987451465185144,1.9085925209979264,2.5370126379799847,0.9031737594044319,0.1954695077304166,-0.24461259530598548,-0.22926842223566576,-0.4142283661153823,-0.5854034026110678,-0.6166980548909288,0.888674836109678,-0.2753383056546045,1.5878678564641069,1.8670145354751024,-1.4997187103625877,-0.3832747697389823,-0.9486089895638056,0.3449570020292946,-0.726655180985889,1.6999404710130017,-0.3523723803792923,-0.522974005179062,-0.5854034026110678,0.10523221520582753,-0.44523349939724377,-0.25996921007055324,-0.46075549648323305,-0.25996921007055324,0.4044403103634737,-2.7506928200117002,-1.2706332542898442,-0.4297244698805092,-0.25996921007055324,0.10523221520582753,-0.3987451465185144,-0.1680153718164889,-0.726655180985889,0.8596469929949846,-0.5697761307887955,0.3002284258115414,4.015957502394453,-0.07650252744056436,0.12030055776561276,0.12030055776561276,1.8114594151764092,0.12030055776561276,0.6992699083324146,0.4341161923697676,0.044842523349634685,-0.2907199213981397,0.4044403103634737,-0.32152087180770866,-0.8372867282398355,2.0328776982252563,1.6299606471660821,0.7139008185990915,0.18045863946931265,-0.21393665194747497,0.6259595854721536,-0.3678171946564402,0.07506070309973252,-0.21393665194747497,0.014577395414097777,-0.8531472312752075,-0.900813798450678,0.6992699083324146,1.062010089223635,0.13535733730271166,-0.9805445753920402,1.4893416625418183,1.2482182125944992,0.5671226765594547,0.3449570020292946,1.936269398935176,2.4018122550596814 | 3,392 |
Organic acid transport | 12 | 51 | 3.042668 | 0.002345 | Q6P4A7,P31751,P08195,P21359,P23786,Q9H2D1,P14174,Q9Y619,P31749,Q9UBX3,O43808,P04083 | Processes and pathways | GO Biological process | msigdb_gobp | 196,101,71,204,205,15,80,87,23,26,219,190 | 2333,2663,219,572,2439,1430,1623,2523,3188,190,2457,1940,928,71,3378,80,204,205,2233,1323,1551,23,101,1571,2905,1093,2648,2005,1256,3178,2120,1661,248,1134,2386,2890,196,961,2352,1083,393,15,702,991,1104,2424,26,1342,2590,469,87 | -0.46075549648323305,-0.6637409727699075,1.5175365324543044,0.7869011513881382,-0.5073997148873077,0.014577395414097777,-0.09172438937674851,-0.5697761307887955,-1.1249806168260381,1.6299606471660821,-0.522974005179062,-0.25996921007055324,0.37472066384711566,2.5774251672985713,-3.3346573519697245,2.455983823206309,1.573819316272094,1.573819316272094,-0.4142283661153823,0.07506070309973252,-0.04609484197467206,3.502130832268083,2.197563227073385,-0.06129269053099454,-0.8372867282398355,0.24043388497129026,-0.6480464817522166,-0.2907199213981397,0.12030055776561276,-1.1088728099650214,-0.3523723803792923,-0.1069583132087397,1.4328440873723212,0.21046898250401078,-0.47629050319229616,-0.8214403202477919,1.6159385005727454,0.3598443506231174,-0.46075549648323305,0.2553993789324403,1.0907625977334081,3.760293155258865,0.6112661660954188,0.3449570020292946,0.24043388497129026,-0.4918385618163464,3.476173526807814,0.07506070309973252,-0.6010440292225467,0.9466108546188425,2.4018122550596814 | 3,392 |
Transport to the golgi and subsequent modification | 28 | 85 | 3.032348 | 0.002427 | Q15363,Q96MW5,Q13561,O43731,Q13813,P24390,Q9Y6B6,Q9BUF5,Q5JRA6,Q13190,O14653,P04066,Q15436,P49755,O15027,O75935,P84085,Q92734,Q9UJW0,Q11206,Q9H9E3,P04350,Q13885,Q14203,Q96PC5,O14579,O60512,Q9Y3B3 | Processes and pathways | Reactome Pathways | msigdb_reactome | 386,403,650,149,663,28,158,426,423,165,289,418,435,565,194,197,586,467,86,353,356,482,503,491,243,252,618,124 | 1426,252,289,2132,194,1568,971,2265,149,618,1856,2060,197,1184,772,815,1519,418,482,948,1433,28,1169,2506,2480,1297,1325,565,3340,2527,2379,1191,2971,1707,801,1680,890,1326,696,1237,586,1381,1682,353,2530,1683,1302,165,1662,650,663,503,491,3180,1044,386,435,1604,2463,423,1667,2127,1717,1414,1531,467,1785,1336,403,243,1035,426,1418,1900,356,1122,1751,86,2189,968,124,3144,158,1799,921 | 0.014577395414097777,1.4186970981267617,1.3194125750424903,-0.3678171946564402,1.6159385005727454,-0.06129269053099454,0.3449570020292946,-0.4297244698805092,1.8253608767518077,0.7139008185990915,-0.21393665194747497,-0.32152087180770866,1.6019075774365181,0.16543634416126807,0.5228837222779321,0.47854849943901234,-0.030908945292574343,1.0476193288474605,0.9176627193149094,0.3598443506231174,0.014577395414097777,3.4241806746156223,0.18045863946931265,-0.5541621697421181,-0.5385614757094254,0.09015227518848501,0.07506070309973252,0.8014705690921952,-1.8662601339900915,-0.5697761307887955,-0.47629050319229616,0.16543634416126807,-0.8849107173056833,-0.13746249502499586,0.4933376536617622,-0.12220433600304552,0.4044403103634737,0.07506070309973252,0.6112661660954188,0.13535733730271166,0.7723215542957492,0.044842523349634685,-0.12220433600304552,1.1910943651123755,-0.5697761307887955,-0.12220433600304552,0.09015227518848501,1.741824390244023,-0.1069583132087397,0.6846286512595186,0.6699770190108111,0.888674836109678,0.9031737594044319,-1.1088728099650214,0.2852966167197613,1.1051243960353279,1.018808669576008,-0.07650252744056436,-0.522974005179062,1.0476193288474605,-0.1069583132087397,-0.3523723803792923,-0.13746249502499586,0.0297158455536117,-0.030908945292574343,0.9466108546188425,-0.1680153718164889,0.07506070309973252,1.0763911704719784,1.461110906640378,0.3002284258115414,1.0476193288474605,0.0297158455536117,-0.22926842223566576,1.1910943651123755,0.22545709717825904,-0.15273282774028654,2.4153666489525016,-0.3832747697389823,0.3598443506231174,1.9915235827542386,-1.0606389558982219,1.8114594151764092,-0.1680153718164889,0.38958597328502204 | 3,392 |
Functional motor deficit | 43 | 148 | 3.024953 | 0.002487 | O75298,P46976,Q13510,Q9NQX3,O14773,P35637,Q9H2D1,O43681,P46020,P10644,P40939,P31749,P53701,P04062,P00846,O14653,O75787,P35670,Q7LG56,P07196,Q9BUK6,Q8TD16,Q93063,O43292,P23786,Q92734,Q9NWM8,O95319,P03886,P00403,P61978,Q08209,P06753,Q9NZJ7,Q9NR77,Q9BQP7,Q13472,Q05639,P07602,Q8IUX1,Q7RTS9,Q15041,Q07021 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 385,258,132,532,140,263,15,523,525,397,277,23,411,32,33,289,429,430,174,178,57,63,577,571,205,467,340,600,220,92,349,232,610,631,108,496,621,620,117,250,507,248,378 | 2191,1828,2941,289,140,571,523,2304,385,1829,429,1758,2336,600,2746,2747,92,2371,33,220,32,610,178,1431,117,2133,3149,397,997,3123,1294,2748,1057,1909,1550,205,2830,1232,1859,3189,2547,1979,2309,1040,23,263,430,2599,952,2236,277,886,525,258,1376,1912,878,2861,3197,2276,2648,411,953,2343,1461,2887,2649,349,1131,2701,1630,3153,620,1599,378,232,1600,934,621,132,1352,3180,2951,1917,248,664,1354,2533,1741,3041,1813,1986,1987,3043,985,174,507,2147,250,2467,2094,1279,1100,640,1386,63,1959,467,2357,2011,2251,577,1960,895,2487,3372,2288,1961,1284,1034,2289,496,57,1261,1263,15,2588,1264,2473,867,532,108,2425,2428,340,631,2742,1481,2224,1875,1826,1125,1651,1798,1566,994,1674,2496 | -0.3987451465185144,-0.19861724574074396,-0.8690218779880967,1.3194125750424903,1.8808822458505576,0.7869011513881382,0.8596469929949846,-0.44523349939724377,1.1051243960353279,-0.19861724574074396,1.0332188640882995,-0.1680153718164889,-0.46075549648323305,0.7431317115189636,-0.726655180985889,-0.726655180985889,2.2930986183056987,-0.47629050319229616,3.2806564295146425,1.5175365324543044,3.2937373551059523,0.7285214102943242,1.6859618908518097,0.014577395414097777,2.0328776982252563,-0.3678171946564402,-1.0767020329756654,1.0763911704719784,0.3300585863237035,-1.0445906823532496,0.09015227518848501,-0.726655180985889,0.2703536119434672,-0.24461259530598548,-0.04609484197467206,1.573819316272094,-0.7897895963070047,0.13535733730271166,-0.21393665194747497,-1.1249806168260381,-0.5854034026110678,-0.2753383056546045,-0.44523349939724377,0.2852966167197613,3.502130832268083,1.3762015415441697,1.0332188640882995,-0.6166980548909288,0.3598443506231174,-0.4142283661153823,1.3478254524900601,0.4044403103634737,0.8596469929949846,1.3903758478681065,0.044842523349634685,-0.24461259530598548,0.4192837063531287,-0.8056079589553966,-1.141103441123685,-0.4297244698805092,-0.6480464817522166,1.062010089223635,0.3598443506231174,-0.46075549648323305,-0.00057286259791032,-0.8214403202477919,-0.6480464817522166,1.1910943651123755,0.21046898250401078,-0.6794490424983824,-0.09172438937674851,-1.0767020329756654,0.7139008185990915,-0.07650252744056436,1.1194765902923671,1.4893416625418183,-0.07650252744056436,0.37472066384711566,0.7139008185990915,1.9085925209979264,0.0599574641453926,-1.1088728099650214,-0.8690218779880967,-0.24461259530598548,1.4328440873723212,0.6699770190108111,0.0599574641453926,-0.5697761307887955,-0.15273282774028654,-0.9486089895638056,-0.18331016512462858,-0.2753383056546045,-0.2753383056546045,-0.9486089895638056,0.3449570020292946,1.6999404710130017,0.888674836109678,-0.3678171946564402,1.4328440873723212,-0.522974005179062,-0.3369402862428846,0.10523221520582753,0.24043388497129026,0.6992699083324146,0.044842523349634685,2.671459958677549,-0.25996921007055324,0.9466108546188425,-0.46075549648323305,-0.2907199213981397,-0.4142283661153823,0.7869011513881382,-0.25996921007055324,0.4044403103634737,-0.5385614757094254,-2.7506928200117002,-0.4297244698805092,-0.25996921007055324,0.10523221520582753,0.3002284258115414,-0.4297244698805092,0.9031737594044319,2.725031627796951,0.12030055776561276,0.12030055776561276,3.760293155258865,-0.6010440292225467,0.12030055776561276,-0.522974005179062,0.4341161923697676,0.8596469929949846,2.1153656498312228,-0.4918385618163464,-0.4918385618163464,1.2196751063114128,0.7139008185990915,-0.710906100634738,-0.00057286259791032,-0.3987451465185144,-0.21393665194747497,-0.18331016512462858,0.22545709717825904,-0.09172438937674851,-0.1680153718164889,-0.04609484197467206,0.3449570020292946,-0.1069583132087397,-0.5385614757094254 | 3,392 |
Fc epsilon receptor fceri signaling | 10 | 53 | 3.018054 | 0.002544 | Q9UL46,O00231,P28072,O43865,P28070,Q08209,P49721,P20618,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,290,227,232,75,236,116,121 | 193,3012,1878,1318,872,1621,312,1396,290,1701,1230,3204,236,929,1231,1832,1659,1322,2168,227,164,1145,2063,1805,759,2169,445,75,1211,1299,1096,1001,116,889,2141,1836,1554,2142,1837,121,232,1274,2007,1684,2888,1353,1867,2794,825,1962,64,1390,1697 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.07506070309973252,0.4192837063531287,-0.09172438937674851,1.262475712405316,0.0297158455536117,1.3194125750424903,-0.13746249502499586,0.13535733730271166,-1.1572413371765422,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,0.07506070309973252,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.32152087180770866,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,0.3300585863237035,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.04609484197467206,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,1.4893416625418183,0.10523221520582753,-0.2907199213981397,-0.12220433600304552,-0.8214403202477919,0.0599574641453926,-0.21393665194747497,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,-0.12220433600304552 | 3,392 |
Regulation of leukocyte migration | 9 | 27 | 2.99666 | 0.00273 | Q11206,Q5JRA6,P09601,P00813,Q08722,P14174,P31749,Q07021,P04083 | Processes and pathways | GO Biological process | msigdb_gobp | 353,423,10,11,490,80,23,378,190 | 1828,2025,11,190,513,1114,10,80,2062,1322,3189,2063,1911,23,2549,2140,2142,1574,1132,378,490,353,423,1687,1669,684,2614 | -0.19861724574074396,-0.30611409685763147,3.888431750187672,1.6299606471660821,0.8741659228684505,0.22545709717825904,3.9012117159107698,2.455983823206309,-0.32152087180770866,0.07506070309973252,-1.1249806168260381,-0.32152087180770866,-0.24461259530598548,3.502130832268083,-0.5854034026110678,-0.3678171946564402,-0.3678171946564402,-0.06129269053099454,0.21046898250401078,1.1194765902923671,0.9031737594044319,1.1910943651123755,1.0476193288474605,-0.12220433600304552,-0.1069583132087397,0.6259595854721536,-0.6166980548909288 | 3,392 |
SLC25 family of mitochondrial transporters | 6 | 22 | 2.995187 | 0.002743 | Q70HW3,Q9H2D1,Q9BSK2,Q9Y6C9,Q9Y619,Q9UBX3 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 44,15,114,213,87,26 | 2663,219,2439,2571,997,1549,2648,1681,1661,562,1445,44,393,114,15,991,2473,631,26,1342,87,213 | -0.6637409727699075,1.5175365324543044,-0.5073997148873077,-0.6010440292225467,0.3300585863237035,-0.04609484197467206,-0.6480464817522166,-0.12220433600304552,-0.1069583132087397,0.8160298348526115,0.014577395414097777,3.0043870268143222,1.0907625977334081,2.074158219188792,3.760293155258865,0.3449570020292946,-0.522974005179062,0.7139008185990915,3.476173526807814,0.07506070309973252,2.4018122550596814,1.5456956922416358 | 3,392 |
Mitochondrial carrier domain superfamily [IPR023395] | 6 | 22 | 2.995187 | 0.002743 | Q70HW3,Q9H2D1,Q9BSK2,Q9Y6C9,Q9Y619,Q9UBX3 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 44,15,114,213,87,26 | 2663,219,2439,2571,997,1549,2648,1681,1661,562,1445,44,393,114,15,991,2473,631,26,1342,87,213 | -0.6637409727699075,1.5175365324543044,-0.5073997148873077,-0.6010440292225467,0.3300585863237035,-0.04609484197467206,-0.6480464817522166,-0.12220433600304552,-0.1069583132087397,0.8160298348526115,0.014577395414097777,3.0043870268143222,1.0907625977334081,2.074158219188792,3.760293155258865,0.3449570020292946,-0.522974005179062,0.7139008185990915,3.476173526807814,0.07506070309973252,2.4018122550596814,1.5456956922416358 | 3,392 |
Mitochondrial substrate/solute carrier [IPR018108] | 6 | 22 | 2.995187 | 0.002743 | Q70HW3,Q9H2D1,Q9BSK2,Q9Y6C9,Q9Y619,Q9UBX3 | Sequence | InterPro Repeat | interpro_repeat | 44,15,114,213,87,26 | 2663,219,2439,2571,997,1549,2648,1681,1661,562,1445,44,393,114,15,991,2473,631,26,1342,87,213 | -0.6637409727699075,1.5175365324543044,-0.5073997148873077,-0.6010440292225467,0.3300585863237035,-0.04609484197467206,-0.6480464817522166,-0.12220433600304552,-0.1069583132087397,0.8160298348526115,0.014577395414097777,3.0043870268143222,1.0907625977334081,2.074158219188792,3.760293155258865,0.3449570020292946,-0.522974005179062,0.7139008185990915,3.476173526807814,0.07506070309973252,2.4018122550596814,1.5456956922416358 | 3,392 |
Clec7a dectin 1 signaling | 10 | 49 | 2.982206 | 0.002862 | Q9UL46,O00231,P28072,O43865,P28070,Q08209,P49721,P20618,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,290,227,232,75,236,116,121 | 193,3012,1878,872,1621,312,1396,290,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,2675,1001,116,889,2141,1836,1837,2604,121,232,2007,1684,2888,1353,1867,1258,2794,825,1962,64,1390,1697 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,1.262475712405316,0.0297158455536117,1.3194125750424903,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,-0.6637409727699075,0.3300585863237035,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,-0.6166980548909288,2.0191011953082207,1.4893416625418183,-0.2907199213981397,-0.12220433600304552,-0.8214403202477919,0.0599574641453926,-0.21393665194747497,0.12030055776561276,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,-0.12220433600304552 | 3,392 |
Paraparesis | 8 | 31 | 2.973946 | 0.00294 | P04062,Q9Y5Y5,Q13510,Q5XKP0,P21359,Q6DKK2,Q9Y619,Q9H6K4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,130,132,200,204,144,87,156 | 429,1758,2108,3188,32,204,1909,2309,263,1147,953,1461,2649,2701,2174,934,1213,132,1741,200,144,1468,2467,1959,156,867,2428,1798,739,130,87 | 1.0332188640882995,-0.1680153718164889,-0.3523723803792923,-1.1249806168260381,3.2937373551059523,1.573819316272094,-0.24461259530598548,-0.44523349939724377,1.3762015415441697,0.1954695077304166,0.3598443506231174,-0.00057286259791032,-0.6480464817522166,-0.6794490424983824,-0.3832747697389823,0.37472066384711566,0.1504025880743201,1.9085925209979264,-0.15273282774028654,1.5878678564641069,1.8670145354751024,-0.00057286259791032,-0.522974005179062,-0.25996921007055324,1.8114594151764092,0.4341161923697676,-0.4918385618163464,-0.1680153718164889,0.5671226765594547,1.936269398935176,2.4018122550596814 | 3,392 |
Signaling by notch4 | 8 | 44 | 2.973869 | 0.002941 | Q9UL46,O00231,P28072,P28070,P49721,P61289,P31749,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,116,23,121 | 193,3012,1878,872,1621,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,23,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,634,1837,121,2007,3081,1684,1353,2794,2418,825,1962,64,1390,2495 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,3.502130832268083,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,0.6992699083324146,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.9965341580527574,-0.12220433600304552,0.0599574641453926,-0.7581946761452075,-0.4918385618163464,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,-0.5385614757094254 | 3,392 |
Abnormality of pulmonary circulation | 10 | 32 | 2.963218 | 0.003044 | P04062,Q14108,P21359,O75844,Q8IZA0,P00403,P31749,P03886,Q9Y4U1,Q9NZ08 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,74,204,50,355,92,23,220,325,191 | 3196,50,3103,795,92,1022,844,220,32,358,2923,204,472,2644,23,788,2198,1271,1406,1026,74,2951,1578,790,1445,355,1640,1848,2615,191,2920,325 | -1.141103441123685,2.8318251529978857,-1.0285571596923793,0.4933376536617622,2.2930986183056987,0.3002284258115414,0.4489377993753778,1.5175365324543044,3.2937373551059523,1.1767898212573111,-0.8531472312752075,1.573819316272094,0.9321417422805507,-0.6480464817522166,3.502130832268083,0.5081160512050436,-0.3987451465185144,0.10523221520582753,0.0297158455536117,0.3002284258115414,2.5370126379799847,-0.8690218779880967,-0.06129269053099454,0.5081160512050436,0.014577395414097777,1.1910943651123755,-0.09172438937674851,-0.19861724574074396,-0.6166980548909288,1.6299606471660821,-0.8372867282398355,1.2482182125944992 | 3,392 |
Abnormal vertebral morphology | 36 | 120 | 2.95114 | 0.003166 | Q6NUQ1,P16435,P00813,P10644,Q8NCH0,P31749,P54802,O60826,O95831,P04062,Q5JRA6,P10619,P04066,Q8TAA9,Q96HY6,Q15436,P34059,Q15427,Q8NFV4,Q8WVQ1,Q9UJX6,Q9UHX1,O75718,Q14108,P21359,Q10713,Q9Y619,Q2M1P5,Q9H9E3,P22413,P61978,O96028,Q7RTS9,Q9Y4P3,Q32P28,Q15056 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 519,516,11,397,22,23,154,409,30,32,423,35,418,296,432,435,180,434,440,322,324,67,454,74,204,83,87,354,356,472,349,226,507,512,249,253 | 3116,2436,2456,1727,1252,2193,2367,2664,1855,409,2964,454,3363,3270,1253,30,226,11,32,418,1113,514,35,397,3135,2477,1144,516,2643,950,2923,204,472,2504,2996,23,2735,180,649,2646,2310,2311,2671,3291,858,694,3373,3191,1406,3292,154,1378,1130,349,1193,2445,980,2508,2529,2835,861,83,1600,587,1633,74,1950,1133,2679,253,2722,434,435,2753,354,249,423,2043,1445,519,3297,507,1528,625,3328,720,2449,2562,22,1306,440,296,1530,322,842,2655,432,1692,3285,2957,2687,723,2257,356,1264,1071,2055,1072,2616,2784,67,2975,324,2329,2190,2001,2939,512,2475,87 | -1.0445906823532496,-0.5073997148873077,-0.522974005179062,-0.15273282774028654,0.12030055776561276,-0.3987451465185144,-0.47629050319229616,-0.6637409727699075,-0.21393665194747497,1.062010089223635,-0.8849107173056833,0.961070082526128,-2.415077244875179,-1.3847856707979227,0.12030055776561276,3.37208282113663,1.5034435722199273,3.888431750187672,3.2937373551059523,1.0476193288474605,0.22545709717825904,0.8741659228684505,3.2151509431473015,1.0763911704719784,-1.0606389558982219,-0.5385614757094254,0.1954695077304166,0.8741659228684505,-0.6480464817522166,0.3598443506231174,-0.8531472312752075,1.573819316272094,0.9321417422805507,-0.5541621697421181,-0.9167311709438607,3.502130832268083,-0.710906100634738,1.671974639280965,0.6846286512595186,-0.6480464817522166,-0.44523349939724377,-0.44523349939724377,-0.6637409727699075,-1.483251123536119,0.4341161923697676,0.6112661660954188,-2.876341695882973,-1.1249806168260381,0.0297158455536117,-1.483251123536119,1.8114594151764092,0.044842523349634685,0.21046898250401078,1.1910943651123755,0.16543634416126807,-0.5073997148873077,0.3449570020292946,-0.5541621697421181,-0.5697761307887955,-0.7897895963070047,0.4341161923697676,2.428913363747869,-0.07650252744056436,0.7723215542957492,-0.09172438937674851,2.5370126379799847,-0.25996921007055324,0.21046898250401078,-0.6637409727699075,1.4186970981267617,-0.6951707365076549,1.018808669576008,1.018808669576008,-0.726655180985889,1.1910943651123755,1.4328440873723212,1.0476193288474605,-0.30611409685763147,0.014577395414097777,0.8741659228684505,-1.4997187103625877,0.888674836109678,-0.030908945292574343,0.7139008185990915,-1.7153094321192972,0.5818477409079303,-0.5073997148873077,-0.5854034026110678,3.553967705609741,0.09015227518848501,1.0043887198247081,1.3051922828493479,-0.030908945292574343,1.2482182125944992,0.4637485581792443,-0.6480464817522166,1.0332188640882995,-0.12220433600304552,-1.4339458950700101,-0.8690218779880967,-0.6637409727699075,0.5818477409079303,-0.4142283661153823,1.1910943651123755,0.12030055776561276,0.2703536119434672,-0.30611409685763147,0.2703536119434672,-0.6166980548909288,-0.7424180239388641,2.644629964151358,-0.8849107173056833,1.2482182125944992,-0.44523349939724377,-0.3832747697389823,-0.2753383056546045,-0.8531472312752075,0.888674836109678,-0.522974005179062,2.4018122550596814 | 3,392 |
Golgi cisterna membrane | 10 | 24 | 2.942467 | 0.003256 | Q11206,Q15363,Q9Y3A3,Q8NBZ7,Q8NBN3,Q10713,O00461,Q08378,Q8WVQ1,Q9Y6B6 | Localization | GO Cellular component | msigdb_gocc | 353,386,98,134,113,83,276,352,322,158 | 276,618,2135,948,3238,2579,352,1682,1098,450,83,353,2530,386,113,134,1414,322,1336,989,869,1515,98,158 | 1.3478254524900601,0.7139008185990915,-0.3678171946564402,0.3598443506231174,-1.2706332542898442,-0.6010440292225467,1.1910943651123755,-0.12220433600304552,0.24043388497129026,0.9755194520783873,2.428913363747869,1.1910943651123755,-0.5697761307887955,1.1051243960353279,2.074158219188792,1.9085925209979264,0.0297158455536117,1.2482182125944992,0.07506070309973252,0.3449570020292946,0.4341161923697676,-0.015734964198557747,2.2522022302138622,1.8114594151764092 | 3,392 |
Protein transporter activity | 6 | 18 | 2.940383 | 0.003278 | Q99595,Q9Y5J9,O60830,Q9NS69,Q9HD20,Q15388 | Functions | GO Molecular function | msigdb_gomf | 6,268,9,42,176,342 | 346,9,1702,1624,1488,565,2067,2834,2120,1029,342,1783,6,176,42,1649,3101,268 | 1.1910943651123755,3.9522705239894336,-0.13746249502499586,-0.09172438937674851,-0.015734964198557747,0.8014705690921952,-0.32152087180770866,-0.7897895963070047,-0.3523723803792923,0.3002284258115414,1.205389452082045,-0.1680153718164889,4.1048668927725505,1.6999404710130017,3.0704404222415245,-0.09172438937674851,-1.0125383355924664,1.3762015415441697 | 3,392 |
Cation transport | 42 | 165 | 2.934294 | 0.003343 | O15173,P05067,Q8N4V1,P61421,P31749,P47985,P62258,P00846,Q13555,O43865,O75027,P24941,Q70HW3,Q9HD20,P35670,Q6KCM7,O75844,Q96GC9,P21796,P08195,P33176,Q13423,O75964,Q7KZN9,Q9UNH7,Q9NWR8,P11413,Q9UDW1,P24539,Q9Y619,P06576,O43808,Q04917,P36543,P00403,Q8IYU8,P20674,Q08209,Q8TAD4,Q8NEW0,Q9H4I9,P27105 | Processes and pathways | GO Biological process | msigdb_gobp | 1,513,529,526,23,537,283,33,34,290,39,547,44,176,430,562,50,186,69,71,455,588,73,329,461,207,337,82,463,87,214,219,474,473,92,485,358,232,110,109,380,376 | 2962,1828,2903,852,1485,1250,1,771,2663,219,290,1972,39,2569,996,2368,1857,50,784,73,1518,1253,92,33,3134,2373,1730,2229,513,2571,2457,214,2502,3076,1431,1432,71,1185,2543,2196,2803,337,997,876,1370,2231,1116,2787,3204,1658,358,950,3347,2923,69,1118,463,547,2644,376,1295,1628,1979,2458,775,786,1551,23,1980,455,1595,430,2403,1860,473,2236,2506,585,2139,537,3035,878,1679,1888,2481,2979,1256,979,2237,1982,954,526,2140,2834,283,819,2314,3178,2120,2579,1681,1770,2701,908,861,474,983,2446,232,3221,1302,933,588,34,1352,2242,2386,2534,562,863,44,329,2285,485,2684,529,1687,109,110,1719,1472,2179,749,2779,186,2217,1083,2762,1788,1928,2289,2492,702,2614,380,991,1104,1020,2473,176,867,2427,207,82,1481,2398,1999,2299,2329,1723,461,2056,739,87,1567 | -0.8849107173056833,-0.19861724574074396,-0.8372867282398355,0.4341161923697676,-0.015734964198557747,0.12030055776561276,4.357302273053826,0.5228837222779321,-0.6637409727699075,1.5175365324543044,1.3194125750424903,-0.2753383056546045,3.136320692524441,-0.6010440292225467,0.3300585863237035,-0.47629050319229616,-0.21393665194747497,2.8318251529978857,0.5081160512050436,2.563961827278685,-0.030908945292574343,0.12030055776561276,2.2930986183056987,3.2806564295146425,-1.0606389558982219,-0.47629050319229616,-0.15273282774028654,-0.4142283661153823,0.8741659228684505,-0.6010440292225467,-0.522974005179062,1.5316205651807586,-0.5541621697421181,-0.9965341580527574,0.014577395414097777,0.014577395414097777,2.5774251672985713,0.16543634416126807,-0.5854034026110678,-0.3987451465185144,-0.7739851845325647,1.2196751063114128,0.3300585863237035,0.4192837063531287,0.044842523349634685,-0.4142283661153823,0.22545709717825904,-0.7581946761452075,-1.1572413371765422,-0.1069583132087397,1.1767898212573111,0.3598443506231174,-2.018657093338504,-0.8531472312752075,2.6043294186857167,0.22545709717825904,0.9466108546188425,0.8305789759854734,-0.6480464817522166,1.1194765902923671,0.09015227518848501,-0.09172438937674851,-0.2753383056546045,-0.522974005179062,0.5228837222779321,0.5081160512050436,-0.04609484197467206,3.502130832268083,-0.2753383056546045,0.961070082526128,-0.07650252744056436,1.0332188640882995,-0.4918385618163464,-0.21393665194747497,0.9321417422805507,-0.4142283661153823,-0.5541621697421181,0.7723215542957492,-0.3678171946564402,0.8451180196791206,-0.9486089895638056,0.4192837063531287,-0.12220433600304552,-0.22926842223566576,-0.5385614757094254,-0.900813798450678,0.12030055776561276,0.3449570020292946,-0.4142283661153823,-0.2753383056546045,0.3598443506231174,0.8596469929949846,-0.3678171946564402,-0.7897895963070047,1.3336236238545365,0.47854849943901234,-0.44523349939724377,-1.1088728099650214,-0.3523723803792923,-0.6010440292225467,-0.12220433600304552,-0.1680153718164889,-0.6794490424983824,0.38958597328502204,0.4341161923697676,0.9321417422805507,0.3449570020292946,-0.5073997148873077,1.4893416625418183,-1.2057460042171027,0.09015227518848501,0.37472066384711566,0.7723215542957492,3.2806564295146425,0.0599574641453926,-0.4142283661153823,-0.47629050319229616,-0.5697761307887955,0.8160298348526115,0.4341161923697676,3.0043870268143222,1.233951351838413,-0.4297244698805092,0.9176627193149094,-0.6637409727699075,0.8596469929949846,-0.12220433600304552,2.1016379298886707,2.1016379298886707,-0.13746249502499586,-0.00057286259791032,-0.3832747697389823,0.5523870051126312,-0.7424180239388641,1.6439740384202233,-0.3987451465185144,0.2553993789324403,-0.726655180985889,-0.1680153718164889,-0.24461259530598548,-0.4297244698805092,-0.5385614757094254,0.6112661660954188,-0.6166980548909288,1.1194765902923671,0.3449570020292946,0.24043388497129026,0.31514907160504646,-0.522974005179062,1.6999404710130017,0.4341161923697676,-0.4918385618163464,1.573819316272094,2.442452416251786,-0.00057286259791032,-0.47629050319229616,-0.2753383056546045,-0.4297244698805092,-0.44523349939724377,-0.13746249502499586,0.961070082526128,-0.30611409685763147,0.5671226765594547,2.4018122550596814,-0.04609484197467206 | 3,392 |
Optic disc pallor | 21 | 52 | 2.933462 | 0.003352 | Q9Y6M9,Q9H061,Q96CU9,Q9Y287,Q9H6K4,O95831,P00846,O43676,O75306,Q8WWY3,Q8WWV3,Q13277,Q9BUK6,Q9UG56,O60313,O43172,Q10713,Q86Y39,P03886,Q8IUX1,Q9NPL8 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 394,12,402,414,156,30,33,38,417,682,699,566,57,192,707,706,83,466,220,250,643 | 2191,1828,2436,1485,1250,706,38,2693,707,2569,417,1857,924,2965,2336,30,795,33,220,2372,2195,2642,2748,2402,1492,3255,3275,1406,2789,83,566,863,466,250,778,1004,1386,699,682,2011,402,1244,1615,57,12,156,643,944,192,414,739,394 | -0.3987451465185144,-0.19861724574074396,-0.5073997148873077,-0.015734964198557747,0.12030055776561276,0.596562227640058,3.149476125453242,-0.6794490424983824,0.596562227640058,-0.6010440292225467,1.0476193288474605,-0.21393665194747497,0.37472066384711566,-0.8849107173056833,-0.46075549648323305,3.37208282113663,0.4933376536617622,3.2806564295146425,1.5175365324543044,-0.47629050319229616,-0.3987451465185144,-0.6480464817522166,-0.726655180985889,-0.4918385618163464,-0.015734964198557747,-1.3357688144594548,-1.4011564023133367,0.0297158455536117,-0.7581946761452075,2.428913363747869,0.8014705690921952,0.4341161923697676,0.9466108546188425,1.4328440873723212,0.5228837222779321,0.3300585863237035,0.044842523349634685,0.6112661660954188,0.6259595854721536,-0.2907199213981397,1.0763911704719784,0.13535733730271166,-0.07650252744056436,2.725031627796951,3.8628534229832154,1.8114594151764092,0.6992699083324146,0.37472066384711566,1.6299606471660821,1.062010089223635,0.5671226765594547,1.0907625977334081 | 3,392 |
Inorganic ion transmembrane transport | 31 | 121 | 2.93098 | 0.003379 | Q8N4V1,P61421,P47985,Q9UBX3,P62258,P00846,O75027,Q9HD20,P35670,Q6KCM7,Q96GC9,P21796,P08195,Q13423,O75964,Q7KZN9,Q9NWR8,P11413,Q9UDW1,P24539,P06576,Q9UHG3,Q04917,P36543,P00403,P51797,Q8IYU8,P20674,Q8TAD4,Q9H4I9,P27105 | Processes and pathways | GO Biological process | msigdb_gobp | 529,526,537,26,283,33,39,176,430,562,186,69,71,588,73,329,207,337,82,463,214,90,474,473,92,228,485,358,110,380,376 | 2903,852,771,1972,39,2569,996,1857,784,73,1253,92,33,1730,2229,2571,2457,214,2502,3076,1432,71,1185,2543,2196,337,997,876,1116,2787,3204,1658,358,950,3347,2923,69,1118,463,2644,376,1295,1628,1979,2458,786,1980,430,2403,1860,473,2236,585,2139,537,3035,878,1679,228,1406,2481,2979,1256,2237,1982,526,2834,283,819,2314,2579,1681,1770,1661,861,474,983,2446,3221,1302,933,588,1352,562,863,329,2285,485,2684,529,1687,110,1719,1472,2179,749,2779,186,2217,2762,1788,2289,2492,702,2614,380,991,1020,176,2427,207,26,82,1481,90,2398,1999,2329,2056,739,1567 | -0.8372867282398355,0.4341161923697676,0.5228837222779321,-0.2753383056546045,3.136320692524441,-0.6010440292225467,0.3300585863237035,-0.21393665194747497,0.5081160512050436,2.563961827278685,0.12030055776561276,2.2930986183056987,3.2806564295146425,-0.15273282774028654,-0.4142283661153823,-0.6010440292225467,-0.522974005179062,1.5316205651807586,-0.5541621697421181,-0.9965341580527574,0.014577395414097777,2.5774251672985713,0.16543634416126807,-0.5854034026110678,-0.3987451465185144,1.2196751063114128,0.3300585863237035,0.4192837063531287,0.22545709717825904,-0.7581946761452075,-1.1572413371765422,-0.1069583132087397,1.1767898212573111,0.3598443506231174,-2.018657093338504,-0.8531472312752075,2.6043294186857167,0.22545709717825904,0.9466108546188425,-0.6480464817522166,1.1194765902923671,0.09015227518848501,-0.09172438937674851,-0.2753383056546045,-0.522974005179062,0.5081160512050436,-0.2753383056546045,1.0332188640882995,-0.4918385618163464,-0.21393665194747497,0.9321417422805507,-0.4142283661153823,0.7723215542957492,-0.3678171946564402,0.8451180196791206,-0.9486089895638056,0.4192837063531287,-0.12220433600304552,1.5034435722199273,0.0297158455536117,-0.5385614757094254,-0.900813798450678,0.12030055776561276,-0.4142283661153823,-0.2753383056546045,0.8596469929949846,-0.7897895963070047,1.3336236238545365,0.47854849943901234,-0.44523349939724377,-0.6010440292225467,-0.12220433600304552,-0.1680153718164889,-0.1069583132087397,0.4341161923697676,0.9321417422805507,0.3449570020292946,-0.5073997148873077,-1.2057460042171027,0.09015227518848501,0.37472066384711566,0.7723215542957492,0.0599574641453926,0.8160298348526115,0.4341161923697676,1.233951351838413,-0.4297244698805092,0.9176627193149094,-0.6637409727699075,0.8596469929949846,-0.12220433600304552,2.1016379298886707,-0.13746249502499586,-0.00057286259791032,-0.3832747697389823,0.5523870051126312,-0.7424180239388641,1.6439740384202233,-0.3987451465185144,-0.726655180985889,-0.1680153718164889,-0.4297244698805092,-0.5385614757094254,0.6112661660954188,-0.6166980548909288,1.1194765902923671,0.3449570020292946,0.31514907160504646,1.6999404710130017,-0.4918385618163464,1.573819316272094,3.476173526807814,2.442452416251786,-0.00057286259791032,2.320323681373693,-0.47629050319229616,-0.2753383056546045,-0.44523349939724377,-0.30611409685763147,0.5671226765594547,-0.04609484197467206 | 3,392 |
Downstream signaling events of b cell receptor bcr | 9 | 44 | 2.927828 | 0.003413 | Q9UL46,O00231,P28072,P28070,Q08209,P49721,P20618,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,232,75,236,116,121 | 193,3012,1878,872,1621,312,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,819,1837,121,232,2007,1684,2888,1353,2794,825,1962,64,1390,1697 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,1.262475712405316,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,0.47854849943901234,-0.19861724574074396,2.0191011953082207,1.4893416625418183,-0.2907199213981397,-0.12220433600304552,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,-0.12220433600304552 | 3,392 |
Cilium assembly | 31 | 68 | 2.924763 | 0.003447 | O95684,Q9Y496,O15078,Q13561,Q9H6D7,P41208,A6NIH7,P62258,Q9BUF5,P53350,P48643,P61163,P06493,Q9NVX0,P30153,P68371,O94927,O75935,Q15691,P23258,Q10713,Q68CZ6,P78371,Q15019,Q9UPT5,P04350,Q14203,Q15154,Q96CS2,O60645,Q13885 | Processes and pathways | Reactome Pathways | msigdb_reactome | 256,129,645,650,21,278,24,283,426,671,797,801,796,316,564,696,318,197,848,582,83,465,210,862,753,482,491,763,373,619,503 | 24,1699,645,972,619,2266,197,318,256,482,796,854,1626,2787,1882,1433,582,564,1254,2310,278,1374,797,1129,2066,2312,671,2551,801,1131,283,1326,696,210,83,1662,650,503,2999,491,3180,862,1240,763,848,3287,465,1716,1357,1306,1257,2776,1531,1335,1720,373,2655,1785,2047,426,2048,2632,21,1646,316,3143,753,129 | 3.4891554290530746,-0.13746249502499586,0.6846286512595186,0.3449570020292946,0.7139008185990915,-0.4297244698805092,1.6019075774365181,1.2482182125944992,1.404541025827467,0.9176627193149094,0.4933376536617622,0.4341161923697676,-0.09172438937674851,-0.7581946761452075,-0.22926842223566576,0.014577395414097777,0.7723215542957492,0.8014705690921952,0.12030055776561276,-0.44523349939724377,1.3478254524900601,0.044842523349634685,0.4933376536617622,0.21046898250401078,-0.32152087180770866,-0.44523349939724377,0.655314983080957,-0.5854034026110678,0.4933376536617622,0.21046898250401078,1.3336236238545365,0.07506070309973252,0.6112661660954188,1.5456956922416358,2.428913363747869,-0.1069583132087397,0.6846286512595186,0.888674836109678,-0.9167311709438607,0.9031737594044319,-1.1088728099650214,0.4341161923697676,0.13535733730271166,0.5376406969420575,0.4489377993753778,-1.4503647779093343,0.9466108546188425,-0.13746249502499586,0.0599574641453926,0.09015227518848501,0.12030055776561276,-0.7424180239388641,-0.030908945292574343,0.07506070309973252,-0.13746249502499586,1.1338192053070948,-0.6480464817522166,-0.1680153718164889,-0.30611409685763147,1.0476193288474605,-0.30611409685763147,-0.6323655241400963,3.5669108013937043,-0.09172438937674851,1.262475712405316,-1.0606389558982219,0.5523870051126312,1.936269398935176 | 3,392 |
Golgi apparatus | 59 | 204 | 2.921534 | 0.003483 | Q9NPR9,Q6NUQ1,Q9BRK5,Q92520,P09601,P05067,Q5VW38,P80303,O75071,Q96MW5,Q6P179,Q8NC54,O95070,O00461,Q8NCH0,Q9Y287,Q9HD45,Q96C57,P24390,Q02818,Q13190,O14653,O60637,Q8TBA6,P35670,Q93050,Q9HB40,P50897,P49755,A1L0T0,Q8WVQ1,Q8TD16,Q93063,Q9UG56,O00231,O15260,O15027,A4D1U4,P67812,Q9NWM8,Q6P4E1,Q9HAS0,Q08378,Q9H3P7,Q8IZA0,Q9UQ16,O43752,Q8N4Q0,Q86SX3,Q8TAD4,Q8NEW0,Q86Y82,Q8NBN3,O60512,Q8NEY8,Q7RTS9,O15212,O14579,Q9NRB3 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 3,519,135,267,10,513,136,13,261,403,16,145,269,276,22,414,287,413,28,159,165,289,41,172,430,175,51,55,565,563,322,63,577,192,193,65,194,581,79,340,85,480,352,606,355,224,225,612,363,110,109,627,113,618,251,507,247,252,255 | 563,1726,581,1054,3115,2876,193,276,252,289,969,194,247,2521,65,1087,2333,2662,2595,2058,225,2106,618,41,1856,1346,261,2964,1973,1319,1347,269,2268,2372,513,3364,10,1187,3062,3122,948,1144,2273,2944,1944,28,2167,1978,2526,649,1169,430,2065,2548,858,2506,1887,998,1325,565,1272,878,798,55,2885,2199,2443,2527,2379,2086,743,79,13,1948,1237,2579,1381,159,861,2604,352,1682,1098,1444,2530,165,3371,1710,2950,1194,1526,1044,1505,1604,1031,3021,935,960,698,136,1987,912,1742,2146,1356,519,1446,16,85,1032,719,638,2754,507,2486,1666,363,3223,1135,627,1384,2813,3306,2149,1305,355,1637,612,2127,779,1717,113,145,22,109,251,110,172,63,2840,2352,322,267,1531,1847,1080,2179,175,577,841,2014,413,1336,403,2565,824,850,989,2394,1018,1199,135,2254,1121,2290,2472,2537,2291,1900,1513,3293,606,1931,1159,1264,2959,480,3084,51,1020,810,287,2424,3,2658,255,1338,2222,340,752,2823,192,2824,2131,2103,2690,870,224,1650,414,3047,968,3186,3144 | 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| 3,392 |
Tetrapyrrole metabolic process | 8 | 21 | 2.921283 | 0.003486 | O00264,P36551,Q9H3L0,O75027,P09601,Q7KZN9,P30519,Q9Y4U1 | Processes and pathways | GO Biological process | msigdb_gobp | 0,377,293,39,10,329,20,325 | 0,39,2109,1209,10,483,20,775,377,2884,679,1986,329,1534,2075,293,2741,1873,2296,811,325 | 4.357302273053826,3.136320692524441,-0.3523723803792923,0.1504025880743201,3.9012117159107698,0.9176627193149094,3.5669108013937043,0.5228837222779321,1.1194765902923671,-0.8214403202477919,0.6259595854721536,-0.2753383056546045,1.233951351838413,-0.030908945292574343,-0.32152087180770866,1.3194125750424903,-0.710906100634738,-0.21393665194747497,-0.4297244698805092,0.4933376536617622,1.2482182125944992 | 3,392 |
Cdt1 association with the cdc6 orc origin complex | 8 | 40 | 2.918763 | 0.003514 | Q9UL46,O00231,P28072,P28070,P49721,P61289,Q9Y619,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,116,87,121 | 193,3012,1878,872,1621,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,121,2007,2888,1353,2794,825,1962,3218,64,1390,87 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,-1.1895625635407403,2.671459958677549,0.044842523349634685,2.4018122550596814 | 3,392 |
Regulation of ras by gaps | 8 | 40 | 2.918035 | 0.003522 | Q9UL46,O00231,P28072,P28070,P49721,P21359,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,204,116,121 | 193,3012,1878,872,1621,1396,1701,1230,236,204,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,121,2007,2720,2888,1353,2794,825,1962,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,1.573819316272094,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.6951707365076549,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685 | 3,392 |
Alzheimers disease and mirna effects | 20 | 91 | 2.913848 | 0.00357 | O95197,P31749,O60282,Q9BUF5,P28072,Q96GC9,O15111,P49720,Q9UJX6,P21796,P33176,Q9NSK0,P49721,P28070,P31751,P45880,Q08209,P04350,P20618,Q13885 | Processes and pathways | WikiPathways | msigdb_wp | 141,23,408,426,164,186,312,445,324,69,455,72,75,227,101,102,232,482,236,503 | 3012,1878,1318,872,1394,1621,312,1396,408,141,482,2641,513,2571,1625,1431,854,2543,1520,997,1549,1228,1116,1402,1230,1884,949,236,69,929,1231,1832,1659,1322,2168,227,164,1145,2063,2458,23,101,455,1595,1805,1373,2002,2857,759,102,2169,1298,2198,445,75,1271,1211,1299,1443,1096,889,2141,1836,1379,696,1770,1862,661,3136,232,2144,2007,745,503,1353,1985,1687,2418,186,1005,825,1962,3345,2536,426,1288,72,869,324,1390,1905 | -0.9326628846066711,-0.22926842223566576,0.07506070309973252,0.4192837063531287,0.0297158455536117,-0.09172438937674851,1.262475712405316,0.0297158455536117,1.062010089223635,1.8808822458505576,0.9176627193149094,-0.6480464817522166,0.8741659228684505,-0.6010440292225467,-0.09172438937674851,0.014577395414097777,0.4341161923697676,-0.5854034026110678,-0.030908945292574343,0.3300585863237035,-0.04609484197467206,0.13535733730271166,0.22545709717825904,0.0297158455536117,0.13535733730271166,-0.22926842223566576,0.3598443506231174,1.4752307813901213,2.6043294186857167,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,0.07506070309973252,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.32152087180770866,-0.522974005179062,3.502130832268083,2.197563227073385,0.961070082526128,-0.07650252744056436,-0.18331016512462858,0.044842523349634685,-0.2907199213981397,-0.8056079589553966,0.5376406969420575,2.197563227073385,-0.3832747697389823,0.09015227518848501,-0.3987451465185144,0.989958989232039,2.5100333281525296,0.10523221520582753,0.1504025880743201,0.09015227518848501,0.014577395414097777,0.24043388497129026,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,0.044842523349634685,0.6112661660954188,-0.1680153718164889,-0.21393665194747497,0.6699770190108111,-1.0606389558982219,1.4893416625418183,-0.3678171946564402,-0.2907199213981397,0.5523870051126312,0.888674836109678,0.0599574641453926,-0.2753383056546045,-0.12220433600304552,-0.4918385618163464,1.6439740384202233,0.3300585863237035,0.47854849943901234,-0.25996921007055324,-2.0016509946323966,-0.5697761307887955,1.0476193288474605,0.10523221520582753,2.5774251672985713,0.4341161923697676,1.2482182125944992,0.044842523349634685,-0.22926842223566576 | 3,392 |
Cis golgi network | 6 | 18 | 2.913358 | 0.003576 | Q9NPR9,Q8TBA6,O00461,Q9UNK9,O43731,P24390 | Localization | GO Cellular component | msigdb_gocc | 3,172,276,570,149,28 | 276,149,772,28,1233,565,2579,1682,1044,1604,1135,172,1414,1531,1336,3,570,1139 | 1.3478254524900601,1.8253608767518077,0.5228837222779321,3.4241806746156223,0.13535733730271166,0.8014705690921952,-0.6010440292225467,-0.12220433600304552,0.2852966167197613,-0.07650252744056436,0.21046898250401078,1.71391040052824,0.0297158455536117,-0.030908945292574343,0.07506070309973252,4.269214878344861,0.8014705690921952,0.21046898250401078 | 3,392 |
Visual loss | 14 | 54 | 2.910121 | 0.003613 | P00846,O75306,O14773,P21359,Q10713,P03886,P40939,P50897,P31749,P07602,Q9NWW5,P53701,P00403,O15460 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 33,417,140,204,83,220,277,55,23,117,118,411,92,407 | 1726,3074,1828,140,645,407,707,417,1857,632,2335,2336,92,2371,33,1022,220,2715,2372,117,1940,2083,2643,204,930,23,1595,2310,858,277,3190,1271,55,1835,1406,1889,411,953,2120,1381,83,2121,3298,2241,1240,1468,2125,1509,467,1960,2957,2536,118,631 | -0.15273282774028654,-0.9965341580527574,-0.19861724574074396,1.8808822458505576,0.6846286512595186,1.062010089223635,0.596562227640058,1.0476193288474605,-0.21393665194747497,0.6992699083324146,-0.46075549648323305,-0.46075549648323305,2.2930986183056987,-0.47629050319229616,3.2806564295146425,0.3002284258115414,1.5175365324543044,-0.6951707365076549,-0.47629050319229616,2.0328776982252563,-0.25996921007055324,-0.3369402862428846,-0.6480464817522166,1.573819316272094,0.37472066384711566,3.502130832268083,-0.07650252744056436,-0.44523349939724377,0.4341161923697676,1.3478254524900601,-1.1249806168260381,0.10523221520582753,2.725031627796951,-0.19861724574074396,0.0297158455536117,-0.22926842223566576,1.062010089223635,0.3598443506231174,-0.3523723803792923,0.044842523349634685,2.428913363747869,-0.3523723803792923,-1.5162026565820805,-0.4142283661153823,0.13535733730271166,-0.00057286259791032,-0.3523723803792923,-0.015734964198557747,0.9466108546188425,-0.25996921007055324,-0.8690218779880967,-0.5697761307887955,2.0328776982252563,0.7139008185990915 | 3,392 |
C type lectin receptors clrs | 10 | 51 | 2.906436 | 0.003656 | Q9UL46,O00231,P28072,O43865,P28070,Q08209,P49721,P20618,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,290,227,232,75,236,116,121 | 193,3012,1878,872,1621,312,1396,290,1701,2787,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,2675,1001,116,889,2141,1836,1837,2604,121,232,1274,2007,1684,2888,1353,1867,1258,2794,825,1962,64,1390,1697 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,1.262475712405316,0.0297158455536117,1.3194125750424903,-0.13746249502499586,-0.7581946761452075,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,-0.6637409727699075,0.3300585863237035,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,-0.6166980548909288,2.0191011953082207,1.4893416625418183,0.10523221520582753,-0.2907199213981397,-0.12220433600304552,-0.8214403202477919,0.0599574641453926,-0.21393665194747497,0.12030055776561276,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,-0.12220433600304552 | 3,392 |
Regulation of runx3 expression and activity | 7 | 39 | 2.894786 | 0.003794 | Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,116,121 | 193,3012,1878,872,1621,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,835,759,2169,445,75,1211,1299,1096,116,889,2141,1836,121,2007,1602,1353,2794,825,1962,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.4637485581792443,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.07650252744056436,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685 | 3,392 |
Copi dependent golgi to er retrograde traffic | 19 | 53 | 2.894255 | 0.003801 | Q9Y496,Q15363,Q6NUQ1,O43731,Q07866,P24390,Q9BUF5,O60333,P49755,P68371,O15260,P33176,Q9NSK0,P84085,P04350,Q9Y3B3,O14579,Q13885,Q9P2W9 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,386,519,149,661,28,426,169,565,696,65,455,72,586,482,124,252,503,125 | 1726,2364,252,65,1936,149,169,2060,3103,874,482,1433,28,455,1169,2506,1325,565,1889,2527,2379,1707,1680,890,696,586,661,2121,717,503,2679,386,519,2511,2127,1717,2708,1531,3098,2074,1035,426,1418,1419,1748,1900,72,1423,125,1751,124,129,3144 | -0.15273282774028654,-0.47629050319229616,1.4186970981267617,2.644629964151358,-0.25996921007055324,1.8253608767518077,1.71391040052824,-0.32152087180770866,-1.0285571596923793,0.4192837063531287,0.9176627193149094,0.014577395414097777,3.4241806746156223,0.961070082526128,0.18045863946931265,-0.5541621697421181,0.07506070309973252,0.8014705690921952,-0.22926842223566576,-0.5697761307887955,-0.47629050319229616,-0.13746249502499586,-0.12220433600304552,0.4044403103634737,0.6112661660954188,0.7723215542957492,0.6699770190108111,-0.3523723803792923,0.5818477409079303,0.888674836109678,-0.6637409727699075,1.1051243960353279,0.8741659228684505,-0.5541621697421181,-0.3523723803792923,-0.13746249502499586,-0.6794490424983824,-0.030908945292574343,-1.0125383355924664,-0.32152087180770866,0.3002284258115414,1.0476193288474605,0.0297158455536117,0.0297158455536117,-0.15273282774028654,-0.22926842223566576,2.5774251672985713,0.0297158455536117,1.977722435244023,-0.15273282774028654,1.9915235827542386,1.936269398935176,-1.0606389558982219 | 3,392 |
Decreased muscle mass | 8 | 20 | 2.891013 | 0.00384 | P46976,O96028,P04066,Q8TAA9,Q9Y487,Q7LG56,Q8NCH0,P31749 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 258,226,418,296,235,174,22,23 | 1253,226,418,2880,23,473,2236,258,1835,2276,953,2835,1599,1633,174,22,296,2052,1125,235 | 0.12030055776561276,1.5034435722199273,1.0476193288474605,-0.8214403202477919,3.502130832268083,0.9321417422805507,-0.4142283661153823,1.3903758478681065,-0.19861724574074396,-0.4297244698805092,0.3598443506231174,-0.7897895963070047,-0.07650252744056436,-0.09172438937674851,1.6999404710130017,3.553967705609741,1.3051922828493479,-0.30611409685763147,0.22545709717825904,1.4893416625418183 | 3,392 |
Regulation of hmox1 expression and activity | 8 | 47 | 2.890897 | 0.003841 | Q9UL46,O00231,P28072,P28070,P09601,P49721,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,10,75,116,121 | 193,3012,1878,872,1621,1396,1701,10,1230,949,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,1837,1379,2604,121,2007,1684,2720,2384,2888,1353,3129,2794,825,1962,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,3.9012117159107698,0.13535733730271166,0.3598443506231174,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,0.044842523349634685,-0.6166980548909288,2.0191011953082207,-0.2907199213981397,-0.12220433600304552,-0.6951707365076549,-0.47629050319229616,-0.8214403202477919,0.0599574641453926,-1.0445906823532496,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685 | 3,392 |
Glycosaminoglycan metabolism | 12 | 19 | 2.882145 | 0.00395 | O43252,Q9NRB3,P08236,P06865,Q7LGA3,Q8TB61,P34059,Q8NCH0,O60512,P54802,Q11206,Q93063 | Processes and pathways | Reactome Pathways | msigdb_reactome | 690,255,514,215,400,508,180,22,618,154,353,577 | 690,727,618,215,2269,514,948,2477,1144,180,154,353,400,22,508,577,255,869,1481 | 0.6112661660954188,0.5671226765594547,0.7139008185990915,1.5316205651807586,-0.4297244698805092,0.8741659228684505,0.3598443506231174,-0.5385614757094254,0.1954695077304166,1.671974639280965,1.8114594151764092,1.1910943651123755,1.0763911704719784,3.553967705609741,0.888674836109678,0.7869011513881382,1.4186970981267617,0.4341161923697676,-0.00057286259791032 | 3,392 |
Cytochrome complex assembly | 8 | 13 | 2.875902 | 0.004029 | Q8N8Q8,Q69YU5,Q7KZN9,Q6DKK2,Q9BSK2,Q15070,O75880,P53701 | Processes and pathways | GO Biological process | msigdb_gobp | 291,5,329,144,114,81,462,411 | 2304,462,537,411,81,5,144,329,291,1219,1036,114,1826 | -0.44523349939724377,0.9466108546188425,0.8451180196791206,1.062010089223635,2.442452416251786,4.180843134947025,1.8670145354751024,1.233951351838413,1.3194125750424903,0.1504025880743201,0.3002284258115414,2.074158219188792,-0.18331016512462858 | 3,392 |
Carboxylic acid transport | 8 | 37 | 2.870514 | 0.004098 | P08195,P21359,Q9H2D1,P14174,P07602,Q9Y619,Q9UBX3,P04083 | Processes and pathways | GO Biological process | msigdb_gobp | 71,204,15,80,117,87,26,190 | 2333,572,2439,1430,1623,190,2457,117,71,80,204,2233,1551,2905,2648,2005,1256,3178,2120,1661,248,1134,2386,2890,961,2352,1083,393,15,702,991,1104,2424,631,26,1342,87 | -0.46075549648323305,0.7869011513881382,-0.5073997148873077,0.014577395414097777,-0.09172438937674851,1.6299606471660821,-0.522974005179062,2.0328776982252563,2.5774251672985713,2.455983823206309,1.573819316272094,-0.4142283661153823,-0.04609484197467206,-0.8372867282398355,-0.6480464817522166,-0.2907199213981397,0.12030055776561276,-1.1088728099650214,-0.3523723803792923,-0.1069583132087397,1.4328440873723212,0.21046898250401078,-0.47629050319229616,-0.8214403202477919,0.3598443506231174,-0.46075549648323305,0.2553993789324403,1.0907625977334081,3.760293155258865,0.6112661660954188,0.3449570020292946,0.24043388497129026,-0.4918385618163464,0.7139008185990915,3.476173526807814,0.07506070309973252,2.4018122550596814 | 3,392 |
Protein import | 17 | 89 | 2.867029 | 0.004143 | O75381,O43615,Q9Y5Y5,O14925,Q99595,Q8N1F7,Q08209,O60830,Q9NS69,O14737,P21359,P40763,Q16539,P31749,Q15388,P40855,O95831 | Processes and pathways | GO Biological process | msigdb_gobp | 280,66,130,346,6,331,232,9,42,341,204,307,343,23,342,93,30 | 1588,1318,2365,341,346,1395,66,691,1907,9,1089,280,2976,1702,794,1594,2746,30,1624,844,1939,796,1626,1858,2028,875,904,3123,2503,2923,204,23,2235,1234,952,307,93,3219,2003,1272,2004,2313,1807,710,464,1378,1462,1301,1598,2444,2604,1632,232,1213,1775,2509,3349,342,2040,1555,343,2244,2410,864,1840,776,2583,331,451,641,2319,1335,1693,3224,1387,6,1788,2843,897,2936,42,1481,2022,2156,1967,689,365,1566,130 | -0.07650252744056436,0.07506070309973252,-0.47629050319229616,1.205389452082045,1.1910943651123755,0.0297158455536117,2.644629964151358,0.6112661660954188,-0.24461259530598548,3.9522705239894336,0.24043388497129026,1.3336236238545365,-0.900813798450678,-0.13746249502499586,0.4933376536617622,-0.07650252744056436,-0.726655180985889,3.37208282113663,-0.09172438937674851,0.4489377993753778,-0.25996921007055324,0.4933376536617622,-0.09172438937674851,-0.21393665194747497,-0.30611409685763147,0.4192837063531287,0.38958597328502204,-1.0445906823532496,-0.5541621697421181,-0.8531472312752075,1.573819316272094,3.502130832268083,-0.4142283661153823,0.13535733730271166,0.3598443506231174,1.2767238749913556,2.2930986183056987,-1.2057460042171027,-0.2907199213981397,0.10523221520582753,-0.2907199213981397,-0.44523349939724377,-0.18331016512462858,0.596562227640058,0.9466108546188425,0.044842523349634685,-0.00057286259791032,0.09015227518848501,-0.07650252744056436,-0.5073997148873077,-0.6166980548909288,-0.09172438937674851,1.4893416625418183,0.1504025880743201,-0.1680153718164889,-0.5541621697421181,-2.052724964852463,1.205389452082045,-0.30611409685763147,-0.04609484197467206,1.205389452082045,-0.4142283661153823,-0.4918385618163464,0.4341161923697676,-0.19861724574074396,0.5228837222779321,-0.6010440292225467,1.233951351838413,0.9755194520783873,0.6992699083324146,-0.44523349939724377,0.07506070309973252,-0.12220433600304552,-1.2057460042171027,0.044842523349634685,4.1048668927725505,-0.1680153718164889,-0.7897895963070047,0.4044403103634737,-0.8531472312752075,3.0704404222415245,-0.00057286259791032,-0.2907199213981397,-0.3678171946564402,-0.25996921007055324,0.6259595854721536,1.162475796263921,-0.04609484197467206,1.936269398935176 | 3,392 |
Golgi to er retrograde transport | 26 | 76 | 2.861599 | 0.004215 | Q9Y496,Q15363,Q6NUQ1,Q13561,O43731,Q07866,P24390,Q9BUF5,O60333,P49755,P68371,Q8TD16,O15260,Q10472,O75935,P33176,Q9NSK0,P84085,Q9UJW0,P68402,P04350,Q13885,Q14203,O14579,Q9Y3B3,Q9P2W9 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,386,519,650,149,661,28,426,169,565,696,63,65,450,197,455,72,586,86,350,482,503,491,252,124,125 | 1726,2364,252,65,2265,1936,149,169,2060,197,3103,874,482,1433,28,455,1169,1374,2506,2480,1297,1325,565,1889,3340,2527,2379,1707,801,1680,890,1326,696,350,586,661,1098,450,2121,717,1662,650,503,491,3180,2679,1134,789,386,519,2511,2127,1717,2708,63,1531,1785,3098,2074,1035,426,1418,1419,1748,1900,1643,2052,72,1423,125,1751,86,124,129,3144,1799 | -0.15273282774028654,-0.47629050319229616,1.4186970981267617,2.644629964151358,-0.4297244698805092,-0.25996921007055324,1.8253608767518077,1.71391040052824,-0.32152087180770866,1.6019075774365181,-1.0285571596923793,0.4192837063531287,0.9176627193149094,0.014577395414097777,3.4241806746156223,0.961070082526128,0.18045863946931265,0.044842523349634685,-0.5541621697421181,-0.5385614757094254,0.09015227518848501,0.07506070309973252,0.8014705690921952,-0.22926842223566576,-1.8662601339900915,-0.5697761307887955,-0.47629050319229616,-0.13746249502499586,0.4933376536617622,-0.12220433600304552,0.4044403103634737,0.07506070309973252,0.6112661660954188,1.1910943651123755,0.7723215542957492,0.6699770190108111,0.24043388497129026,0.9755194520783873,-0.3523723803792923,0.5818477409079303,-0.1069583132087397,0.6846286512595186,0.888674836109678,0.9031737594044319,-1.1088728099650214,-0.6637409727699075,0.21046898250401078,0.5081160512050436,1.1051243960353279,0.8741659228684505,-0.5541621697421181,-0.3523723803792923,-0.13746249502499586,-0.6794490424983824,2.671459958677549,-0.030908945292574343,-0.1680153718164889,-1.0125383355924664,-0.32152087180770866,0.3002284258115414,1.0476193288474605,0.0297158455536117,0.0297158455536117,-0.15273282774028654,-0.22926842223566576,-0.09172438937674851,-0.30611409685763147,2.5774251672985713,0.0297158455536117,1.977722435244023,-0.15273282774028654,2.4153666489525016,1.9915235827542386,1.936269398935176,-1.0606389558982219,-0.1680153718164889 | 3,392 |
Cation transmembrane transporter activity | 23 | 79 | 2.855458 | 0.004297 | Q8N4V1,P61421,P47985,P00846,Q70HW3,Q9HD20,Q93050,P35670,P08195,Q13423,O75964,Q7KZN9,Q9UDW1,P24539,Q9Y619,P06576,O43808,P36543,P00403,P20674,Q9Y487,Q8TAD4,Q8NEW0 | Functions | GO Molecular function | msigdb_gomf | 529,526,537,33,44,176,175,430,71,588,73,329,82,463,87,214,219,473,92,358,235,110,109 | 852,2663,219,784,73,1518,1253,92,33,1730,2229,2571,214,2502,3076,1432,71,1185,2196,997,876,1116,1658,358,950,3347,1118,463,2644,1979,1551,1980,430,1860,473,2236,537,3035,1679,1256,2237,1982,526,2834,2579,1681,1770,861,588,2386,863,44,329,529,1687,109,110,1472,2179,175,2779,1083,1928,2492,702,991,1104,1020,2473,176,867,2427,82,2398,2329,235,617,87,1567 | 0.4341161923697676,-0.6637409727699075,1.5175365324543044,0.5081160512050436,2.563961827278685,-0.030908945292574343,0.12030055776561276,2.2930986183056987,3.2806564295146425,-0.15273282774028654,-0.4142283661153823,-0.6010440292225467,1.5316205651807586,-0.5541621697421181,-0.9965341580527574,0.014577395414097777,2.5774251672985713,0.16543634416126807,-0.3987451465185144,0.3300585863237035,0.4192837063531287,0.22545709717825904,-0.1069583132087397,1.1767898212573111,0.3598443506231174,-2.018657093338504,0.22545709717825904,0.9466108546188425,-0.6480464817522166,-0.2753383056546045,-0.04609484197467206,-0.2753383056546045,1.0332188640882995,-0.21393665194747497,0.9321417422805507,-0.4142283661153823,0.8451180196791206,-0.9486089895638056,-0.12220433600304552,0.12030055776561276,-0.4142283661153823,-0.2753383056546045,0.8596469929949846,-0.7897895963070047,-0.6010440292225467,-0.12220433600304552,-0.1680153718164889,0.4341161923697676,0.7723215542957492,-0.47629050319229616,0.4341161923697676,3.0043870268143222,1.233951351838413,0.8596469929949846,-0.12220433600304552,2.1016379298886707,2.1016379298886707,-0.00057286259791032,-0.3832747697389823,1.6999404710130017,-0.7424180239388641,0.2553993789324403,-0.24461259530598548,-0.5385614757094254,0.6112661660954188,0.3449570020292946,0.24043388497129026,0.31514907160504646,-0.522974005179062,1.6999404710130017,0.4341161923697676,-0.4918385618163464,2.442452416251786,-0.47629050319229616,-0.44523349939724377,1.4893416625418183,0.7285214102943242,2.4018122550596814,-0.04609484197467206 | 3,392 |
EF-hand domain pair [IPR011992] | 24 | 55 | 2.854651 | 0.004308 | Q9BRK5,Q9Y4J8,Q9UMZ2,O75071,P80303,O43707,P41208,Q8N163,P30626,O43852,Q13813,Q02818,Q99584,P04632,Q6KCM7,P14649,Q96AY3,P12814,Q9NWM8,Q8IYU8,Q14257,Q9H8M7,Q9Y680,P60660 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 135,658,656,261,13,771,278,279,786,151,663,159,425,678,562,54,842,708,340,485,99,770,122,119 | 771,151,261,1829,2439,1253,678,1431,2543,708,3135,2230,54,1402,3204,786,1946,278,1009,2673,2139,119,1522,13,159,1631,663,99,2838,1919,849,562,1445,2813,1557,2249,485,279,1957,842,1927,425,2289,135,1051,916,770,340,1138,3253,1342,656,1934,658,122 | 0.5228837222779321,1.8114594151764092,1.3762015415441697,-0.19861724574074396,-0.5073997148873077,0.12030055776561276,0.6259595854721536,0.014577395414097777,-0.5854034026110678,0.596562227640058,-1.0606389558982219,-0.4142283661153823,2.725031627796951,0.0297158455536117,-1.1572413371765422,0.5081160512050436,-0.25996921007055324,1.3478254524900601,0.31514907160504646,-0.6637409727699075,-0.3678171946564402,2.0191011953082207,-0.030908945292574343,3.8500550386939207,1.7975494659955786,-0.09172438937674851,0.6699770190108111,2.224898571271148,-0.7897895963070047,-0.24461259530598548,0.4489377993753778,0.8160298348526115,0.014577395414097777,-0.7739851845325647,-0.04609484197467206,-0.4142283661153823,0.9176627193149094,1.3478254524900601,-0.25996921007055324,0.4637485581792443,-0.24461259530598548,1.0476193288474605,-0.4297244698805092,1.9085925209979264,0.2852966167197613,0.38958597328502204,0.5376406969420575,1.2196751063114128,0.21046898250401078,-1.319461443687167,0.07506070309973252,0.6846286512595186,-0.24461259530598548,0.6846286512595186,2.0191011953082207 | 3,392 |
Variable expressivity | 28 | 83 | 2.84673 | 0.004417 | P46976,P00374,Q13510,Q9H061,P17900,Q13813,Q9BUF5,Q70HW3,Q9BV79,P35270,P07196,Q15427,Q8WVQ1,Q8TD16,Q6P4A7,P23258,P09622,P03886,P00403,P04350,P06753,Q9NZJ7,Q9NR77,Q13868,P07602,Q9Y263,Q13885,Q8NI60 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 258,4,132,12,146,663,426,44,48,560,178,434,322,63,196,582,594,220,92,482,610,631,108,622,117,644,503,640 | 2191,2877,1828,1367,771,1879,1729,2336,2306,1269,4,92,844,220,482,610,178,117,2133,2026,594,3378,146,582,905,560,2236,1059,3282,1374,886,258,1376,1011,1912,1889,953,2343,1461,2088,1378,2575,2281,2701,1599,2121,132,663,622,503,2008,2722,434,1813,1814,1986,196,3043,44,640,1386,63,322,895,426,48,12,809,2185,1264,2294,108,2078,3314,631,1752,688,644,1826,1969,1798,739,994 | -0.3987451465185144,-0.8214403202477919,-0.19861724574074396,0.044842523349634685,0.5228837222779321,-0.22926842223566576,-0.15273282774028654,-0.46075549648323305,-0.44523349939724377,0.10523221520582753,4.25660783544249,2.2930986183056987,0.4489377993753778,1.5175365324543044,0.9176627193149094,0.7285214102943242,1.6859618908518097,2.0328776982252563,-0.3678171946564402,-0.30611409685763147,0.7577317502408601,-3.3346573519697245,1.8531384170199579,0.7723215542957492,0.38958597328502204,0.8160298348526115,-0.4142283661153823,0.2703536119434672,-1.4339458950700101,0.044842523349634685,0.4044403103634737,1.3903758478681065,0.044842523349634685,0.31514907160504646,-0.24461259530598548,-0.22926842223566576,0.3598443506231174,-0.46075549648323305,-0.00057286259791032,-0.3369402862428846,0.044842523349634685,-0.6010440292225467,-0.4297244698805092,-0.6794490424983824,-0.07650252744056436,-0.3523723803792923,1.9085925209979264,0.6699770190108111,0.7139008185990915,0.888674836109678,-0.2907199213981397,-0.6951707365076549,1.018808669576008,-0.18331016512462858,-0.18331016512462858,-0.2753383056546045,1.6159385005727454,-0.9486089895638056,3.0043870268143222,0.6992699083324146,0.044842523349634685,2.671459958677549,1.2482182125944992,0.4044403103634737,1.0476193288474605,2.858451368283087,3.8628534229832154,0.4933376536617622,-0.3832747697389823,0.12030055776561276,-0.4297244698805092,2.1153656498312228,-0.32152087180770866,-1.6154534426268758,0.7139008185990915,-0.15273282774028654,0.6259595854721536,0.6992699083324146,-0.18331016512462858,-0.25996921007055324,-0.1680153718164889,0.5671226765594547,0.3449570020292946 | 3,392 |
Proteasome | 7 | 36 | 2.84009 | 0.00451 | Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323 | Processes and pathways | KEGG Pathways | msigdb_kegg | 64,193,164,227,75,116,121 | 193,3012,872,1621,1396,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,121,2007,2888,1353,2794,825,1962,64,1390 | 1.6159385005727454,-0.9326628846066711,0.4192837063531287,-0.09172438937674851,0.0297158455536117,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685 | 3,392 |
Inorganic anion transport | 8 | 26 | 2.825667 | 0.004718 | P51797,Q9UHG3,P21796,P45880,Q9H813,Q9UBX3,Q9C0H2,P22413 | Processes and pathways | GO Biological process | msigdb_gobp | 228,90,69,102,381,26,95,472 | 2434,2333,523,1976,928,2135,69,472,775,102,1679,228,1406,1256,1681,1661,3264,2352,1244,95,1748,381,26,90,1905,1567 | -0.5073997148873077,-0.46075549648323305,0.8596469929949846,-0.2753383056546045,0.37472066384711566,-0.3678171946564402,2.6043294186857167,0.9321417422805507,0.5228837222779321,2.197563227073385,-0.12220433600304552,1.5034435722199273,0.0297158455536117,0.12030055776561276,-0.12220433600304552,-0.1069583132087397,-1.352091936483502,-0.46075549648323305,0.13535733730271166,2.2930986183056987,-0.15273282774028654,1.1194765902923671,3.476173526807814,2.320323681373693,-0.22926842223566576,-0.04609484197467206 | 3,392 |
Muscle contraction | 7 | 26 | 2.825002 | 0.004728 | Q13555,O43865,P09493,P08670,P14649,P60660,P04083 | Processes and pathways | Reactome Pathways | msigdb_reactome | 34,290,105,111,54,119,190 | 290,190,1730,2229,610,3076,1432,111,105,54,1116,2787,2524,1658,1118,2115,786,2979,119,295,1173,2173,1274,34,828,1876 | 1.3194125750424903,1.6299606471660821,-0.15273282774028654,-0.4142283661153823,0.7285214102943242,-0.9965341580527574,0.014577395414097777,2.087902125825021,2.1701960548718655,2.725031627796951,0.22545709717825904,-0.7581946761452075,-0.5697761307887955,-0.1069583132087397,0.22545709717825904,-0.3523723803792923,0.5081160512050436,-0.900813798450678,2.0191011953082207,1.3051922828493479,0.18045863946931265,-0.3832747697389823,0.10523221520582753,3.2806564295146425,0.47854849943901234,-0.21393665194747497 | 3,392 |
calmodulin-related | 7 | 14 | 2.824806 | 0.004731 | Q02818,Q99584,Q14257,Q9BRK5,P80303,P41208,O43852 | Functions | Panther Protein class | panther_protein_class | 159,425,99,135,13,278,151 | 151,2543,786,1946,278,1522,13,159,99,1919,485,425,2289,135 | 1.8114594151764092,-0.5854034026110678,0.5081160512050436,-0.25996921007055324,1.3478254524900601,-0.030908945292574343,3.8500550386939207,1.7975494659955786,2.224898571271148,-0.24461259530598548,0.9176627193149094,1.0476193288474605,-0.4297244698805092,1.9085925209979264 | 3,392 |
Alzheimers disease | 19 | 88 | 2.822533 | 0.004765 | O95197,P31749,O60282,Q9BUF5,P28072,O15111,P49720,Q9UJX6,P21796,P33176,Q9NSK0,P49721,P28070,P31751,P45880,Q08209,P04350,P20618,Q13885 | Processes and pathways | WikiPathways | msigdb_wp | 141,23,408,426,164,312,445,324,69,455,72,75,227,101,102,232,482,236,503 | 3012,1878,1318,872,1394,1621,312,1396,408,141,482,2641,513,2571,1625,1431,854,2543,1520,997,1549,1228,1116,1402,1230,1884,949,236,69,929,1231,1832,1659,1322,2168,227,164,1145,2063,2458,23,101,455,1595,1805,1373,2002,2857,759,102,2169,1298,2198,445,75,1271,1211,1299,1443,1096,889,2141,1836,1379,696,1770,1862,661,3136,232,2144,2007,745,503,1353,1985,1687,2418,825,1962,3345,2536,426,1288,72,324,1390,1905 | -0.9326628846066711,-0.22926842223566576,0.07506070309973252,0.4192837063531287,0.0297158455536117,-0.09172438937674851,1.262475712405316,0.0297158455536117,1.062010089223635,1.8808822458505576,0.9176627193149094,-0.6480464817522166,0.8741659228684505,-0.6010440292225467,-0.09172438937674851,0.014577395414097777,0.4341161923697676,-0.5854034026110678,-0.030908945292574343,0.3300585863237035,-0.04609484197467206,0.13535733730271166,0.22545709717825904,0.0297158455536117,0.13535733730271166,-0.22926842223566576,0.3598443506231174,1.4752307813901213,2.6043294186857167,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,0.07506070309973252,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.32152087180770866,-0.522974005179062,3.502130832268083,2.197563227073385,0.961070082526128,-0.07650252744056436,-0.18331016512462858,0.044842523349634685,-0.2907199213981397,-0.8056079589553966,0.5376406969420575,2.197563227073385,-0.3832747697389823,0.09015227518848501,-0.3987451465185144,0.989958989232039,2.5100333281525296,0.10523221520582753,0.1504025880743201,0.09015227518848501,0.014577395414097777,0.24043388497129026,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,0.044842523349634685,0.6112661660954188,-0.1680153718164889,-0.21393665194747497,0.6699770190108111,-1.0606389558982219,1.4893416625418183,-0.3678171946564402,-0.2907199213981397,0.5523870051126312,0.888674836109678,0.0599574641453926,-0.2753383056546045,-0.12220433600304552,-0.4918385618163464,0.47854849943901234,-0.25996921007055324,-2.0016509946323966,-0.5697761307887955,1.0476193288474605,0.10523221520582753,2.5774251672985713,1.2482182125944992,0.044842523349634685,-0.22926842223566576 | 3,392 |
Organelle biogenesis and maintenance | 45 | 104 | 2.82049 | 0.004795 | O95684,Q9Y496,Q9BZK7,Q9BUR5,O15078,Q13561,Q9H6D7,O75947,P41208,A6NIH7,P62258,Q13505,Q9BUF5,P00846,P53350,P48643,P61163,P06493,P30153,Q9NVX0,P68371,O75431,Q86X55,O75935,O94927,Q5XKP0,O75964,Q15691,P23258,P24539,Q10713,Q68CZ6,P78371,Q16539,Q9NX63,P06576,Q15019,Q9UPT5,P04350,Q9Y512,Q14203,Q15154,O60645,Q96CS2,Q13885 | Processes and pathways | Reactome Pathways | msigdb_reactome | 256,129,655,531,645,650,21,784,278,24,283,31,426,33,671,797,801,796,564,316,696,692,68,197,318,200,73,848,582,463,83,465,210,343,868,214,862,753,482,365,491,763,619,373,503 | 24,1393,1699,645,972,619,692,2266,197,784,73,318,256,1142,33,3274,482,796,214,854,1626,2787,1882,1433,582,463,2644,1979,564,1254,2310,1860,2671,278,1374,3035,797,3373,1129,2066,2312,2832,671,1442,2086,2237,1982,2551,801,1131,283,1326,696,210,2280,932,83,1662,31,650,503,2999,491,3180,862,1240,763,2040,848,343,1214,200,3287,465,2350,1716,1357,68,1306,1257,2776,3376,1531,1335,1720,373,2655,1785,2047,1284,426,531,2048,2632,655,21,1646,1389,316,868,3143,753,129,365 | 3.4891554290530746,0.0297158455536117,-0.13746249502499586,0.6846286512595186,0.3449570020292946,0.7139008185990915,0.6112661660954188,-0.4297244698805092,1.6019075774365181,0.5081160512050436,2.563961827278685,1.2482182125944992,1.404541025827467,0.1954695077304166,3.2806564295146425,-1.4011564023133367,0.9176627193149094,0.4933376536617622,1.5316205651807586,0.4341161923697676,-0.09172438937674851,-0.7581946761452075,-0.22926842223566576,0.014577395414097777,0.7723215542957492,0.9466108546188425,-0.6480464817522166,-0.2753383056546045,0.8014705690921952,0.12030055776561276,-0.44523349939724377,-0.21393665194747497,-0.6637409727699075,1.3478254524900601,0.044842523349634685,-0.9486089895638056,0.4933376536617622,-2.876341695882973,0.21046898250401078,-0.32152087180770866,-0.44523349939724377,-0.7897895963070047,0.655314983080957,0.014577395414097777,-0.3369402862428846,-0.4142283661153823,-0.2753383056546045,-0.5854034026110678,0.4933376536617622,0.21046898250401078,1.3336236238545365,0.07506070309973252,0.6112661660954188,1.5456956922416358,-0.4297244698805092,0.37472066384711566,2.428913363747869,-0.1069583132087397,3.359041854851364,0.6846286512595186,0.888674836109678,-0.9167311709438607,0.9031737594044319,-1.1088728099650214,0.4341161923697676,0.13535733730271166,0.5376406969420575,-0.30611409685763147,0.4489377993753778,1.205389452082045,0.1504025880743201,1.5878678564641069,-1.4503647779093343,0.9466108546188425,-0.46075549648323305,-0.13746249502499586,0.0599574641453926,2.6177703621148702,0.09015227518848501,0.12030055776561276,-0.7424180239388641,-2.966784310329377,-0.030908945292574343,0.07506070309973252,-0.13746249502499586,1.1338192053070948,-0.6480464817522166,-0.1680153718164889,-0.30611409685763147,0.10523221520582753,1.0476193288474605,0.8596469929949846,-0.30611409685763147,-0.6323655241400963,0.6846286512595186,3.5669108013937043,-0.09172438937674851,0.044842523349634685,1.262475712405316,0.4341161923697676,-1.0606389558982219,0.5523870051126312,1.936269398935176,1.162475796263921 | 3,392 |
Sensorimotor neuropathy | 8 | 32 | 2.811718 | 0.004928 | P00846,Q9NR77,Q7LG56,P07196,P07602,P03886,O95831,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 33,108,174,178,117,220,30,92 | 1828,2594,707,30,92,33,220,1730,178,117,2716,2308,758,277,2905,1912,1835,953,1461,2887,2121,2202,1354,3021,174,2450,467,1787,108,2055,631,739 | -0.19861724574074396,-0.6166980548909288,0.596562227640058,3.37208282113663,2.2930986183056987,3.2806564295146425,1.5175365324543044,-0.15273282774028654,1.6859618908518097,2.0328776982252563,-0.6951707365076549,-0.44523349939724377,0.5376406969420575,1.3478254524900601,-0.8372867282398355,-0.24461259530598548,-0.19861724574074396,0.3598443506231174,-0.00057286259791032,-0.8214403202477919,-0.3523723803792923,-0.3987451465185144,0.0599574641453926,-0.9326628846066711,1.6999404710130017,-0.5073997148873077,0.9466108546188425,-0.1680153718164889,2.1153656498312228,-0.30611409685763147,0.7139008185990915,0.5671226765594547 | 3,392 |
Er to golgi anterograde transport | 25 | 80 | 2.809757 | 0.004958 | Q15363,Q96MW5,Q13561,O43731,Q13813,P24390,Q9Y6B6,Q9BUF5,Q5JRA6,Q13190,O14653,Q15436,P49755,O15027,O75935,P84085,Q92734,Q9UJW0,Q9H9E3,P04350,Q13885,Q9Y3B3,Q14203,Q96PC5,O14579 | Processes and pathways | Reactome Pathways | msigdb_reactome | 386,403,650,149,663,28,158,426,423,165,289,435,565,194,197,586,467,86,356,482,503,124,491,243,252 | 1426,252,289,2132,194,1568,971,2265,149,1856,2060,197,1184,772,815,1519,482,1433,28,1169,2506,2480,1297,1325,565,3340,2527,2379,1191,2971,1707,801,1680,890,1326,696,1237,586,1381,1682,2530,1683,1302,165,1662,650,663,503,491,3180,1044,386,435,2463,423,1667,2127,1717,1414,1531,467,1785,1336,403,243,1035,426,1418,1900,356,1122,1751,86,2189,968,124,3144,158,1799,921 | 0.014577395414097777,1.4186970981267617,1.3194125750424903,-0.3678171946564402,1.6159385005727454,-0.06129269053099454,0.3449570020292946,-0.4297244698805092,1.8253608767518077,-0.21393665194747497,-0.32152087180770866,1.6019075774365181,0.16543634416126807,0.5228837222779321,0.47854849943901234,-0.030908945292574343,0.9176627193149094,0.014577395414097777,3.4241806746156223,0.18045863946931265,-0.5541621697421181,-0.5385614757094254,0.09015227518848501,0.07506070309973252,0.8014705690921952,-1.8662601339900915,-0.5697761307887955,-0.47629050319229616,0.16543634416126807,-0.8849107173056833,-0.13746249502499586,0.4933376536617622,-0.12220433600304552,0.4044403103634737,0.07506070309973252,0.6112661660954188,0.13535733730271166,0.7723215542957492,0.044842523349634685,-0.12220433600304552,-0.5697761307887955,-0.12220433600304552,0.09015227518848501,1.741824390244023,-0.1069583132087397,0.6846286512595186,0.6699770190108111,0.888674836109678,0.9031737594044319,-1.1088728099650214,0.2852966167197613,1.1051243960353279,1.018808669576008,-0.522974005179062,1.0476193288474605,-0.1069583132087397,-0.3523723803792923,-0.13746249502499586,0.0297158455536117,-0.030908945292574343,0.9466108546188425,-0.1680153718164889,0.07506070309973252,1.0763911704719784,1.461110906640378,0.3002284258115414,1.0476193288474605,0.0297158455536117,-0.22926842223566576,1.1910943651123755,0.22545709717825904,-0.15273282774028654,2.4153666489525016,-0.3832747697389823,0.3598443506231174,1.9915235827542386,-1.0606389558982219,1.8114594151764092,-0.1680153718164889,0.38958597328502204 | 3,392 |
Degradation of axin | 7 | 38 | 2.809311 | 0.004965 | Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,116,121 | 193,3012,1878,872,1621,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,121,2007,2888,1353,2794,825,1962,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685 | 3,392 |
Scf skp2 mediated degradation of p27 p21 | 7 | 41 | 2.808919 | 0.004971 | Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,116,121 | 193,3012,1878,872,1621,1396,1701,1548,1230,236,547,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,1837,121,2007,1684,1353,2794,825,1962,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,-0.04609484197467206,0.13535733730271166,1.4752307813901213,0.8305789759854734,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.12220433600304552,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685 | 3,392 |
ER-Golgi transport | 15 | 53 | 2.808589 | 0.004976 | Q15363,Q5JRA6,O15027,Q6NUQ1,O95197,Q9Y282,Q92734,O95070,Q15436,O14579,O43731,P49755,P24390,Q9P2W9,Q9Y6B6 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 386,423,194,519,141,14,467,269,435,252,149,565,28,125,158 | 252,194,1568,971,1936,149,1856,2060,1184,269,141,772,815,1519,1433,28,1169,1325,565,3238,2527,2379,2971,1707,1172,1680,890,586,717,2720,386,435,423,519,2147,1667,2127,1717,1414,467,700,824,1035,1122,2636,1423,125,1751,14,2189,1585,3144,158 | 1.4186970981267617,1.6159385005727454,-0.06129269053099454,0.3449570020292946,-0.25996921007055324,1.8253608767518077,-0.21393665194747497,-0.32152087180770866,0.16543634416126807,1.362018084052379,1.8808822458505576,0.5228837222779321,0.47854849943901234,-0.030908945292574343,0.014577395414097777,3.4241806746156223,0.18045863946931265,0.07506070309973252,0.8014705690921952,-1.2706332542898442,-0.5697761307887955,-0.47629050319229616,-0.8849107173056833,-0.13746249502499586,0.18045863946931265,-0.12220433600304552,0.4044403103634737,0.7723215542957492,0.5818477409079303,-0.6951707365076549,1.1051243960353279,1.018808669576008,1.0476193288474605,0.8741659228684505,-0.3678171946564402,-0.1069583132087397,-0.3523723803792923,-0.13746249502499586,0.0297158455536117,0.9466108546188425,0.6112661660954188,0.47854849943901234,0.3002284258115414,0.22545709717825904,-0.6323655241400963,0.0297158455536117,1.977722435244023,-0.15273282774028654,3.7859704508763934,-0.3832747697389823,-0.06129269053099454,-1.0606389558982219,1.8114594151764092 | 3,392 |
Hedgehog on state | 10 | 44 | 2.803659 | 0.005053 | Q9UL46,Q9Y496,O00231,P28072,P28070,P49721,P20618,P61289,Q06323,Q2M1P5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,129,193,164,227,75,236,116,121,354 | 193,3012,1878,872,1621,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,1298,445,75,1211,1299,1096,116,889,2141,1836,121,2007,2720,2888,1353,354,2628,2794,1692,825,1962,64,1390,129 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.09015227518848501,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.6951707365076549,-0.8214403202477919,0.0599574641453926,1.1910943651123755,-0.6323655241400963,-0.7581946761452075,-0.12220433600304552,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,1.936269398935176 | 3,392 |
Cross presentation of soluble exogenous antigens endosomes | 7 | 39 | 2.798971 | 0.005127 | Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,116,121 | 193,3012,1878,872,1621,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,121,2007,2888,1353,2794,825,1962,1795,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,-0.1680153718164889,2.671459958677549,0.044842523349634685 | 3,392 |
Reduced visual acuity | 39 | 126 | 2.798866 | 0.005128 | Q15555,Q9Y6M9,Q9H061,O15078,Q96CU9,O43681,P17900,P31749,Q9H6K4,Q86YV9,P53701,P00846,O43676,O75306,Q8WWY3,Q8WWV3,P50897,Q13277,P68371,P46100,Q9Y4U1,Q9NZ08,Q9UHX1,O60313,P21359,O43172,Q10713,Q86Y39,P09622,Q9Y4W6,P06865,P03886,P51797,Q9NZJ7,Q7Z3E5,P07602,Q8IUX1,Q9NPL8,Q07021 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 504,394,12,645,402,523,146,23,156,542,411,33,38,417,682,699,55,566,696,694,325,191,67,707,204,706,83,466,594,739,215,220,228,631,625,117,250,643,378 | 1726,3074,2876,2191,1828,1318,645,2713,706,873,727,38,523,2693,707,1460,2569,417,924,2965,2266,2786,795,2371,33,1022,220,2715,2109,215,117,2269,1940,3148,594,3377,2195,1144,146,2748,2402,1492,2923,204,1909,2114,3255,1233,2309,23,1552,1595,2065,2310,2311,1059,694,2198,887,3275,1271,1236,55,228,1406,1889,411,953,1573,2140,1462,2142,696,2529,2835,378,83,1328,566,1149,1240,504,2706,1468,625,2464,466,542,250,2449,778,1386,699,682,1049,2011,1960,402,1416,1158,1244,806,2075,2536,2656,1615,2048,12,2738,156,1264,643,2017,191,631,944,2742,1481,67,2155,2104,1207,325,739,994,394 | -0.15273282774028654,-0.9965341580527574,-0.8214403202477919,-0.3987451465185144,-0.19861724574074396,0.07506070309973252,0.6846286512595186,-0.6951707365076549,0.596562227640058,0.4192837063531287,0.5671226765594547,3.149476125453242,0.8596469929949846,-0.6794490424983824,0.596562227640058,-0.00057286259791032,-0.6010440292225467,1.0476193288474605,0.37472066384711566,-0.8849107173056833,-0.4297244698805092,-0.7581946761452075,0.4933376536617622,-0.47629050319229616,3.2806564295146425,0.3002284258115414,1.5175365324543044,-0.6951707365076549,-0.3523723803792923,1.5316205651807586,2.0328776982252563,-0.4297244698805092,-0.25996921007055324,-1.0767020329756654,0.7577317502408601,-3.241741434427683,-0.3987451465185144,0.1954695077304166,1.8531384170199579,-0.726655180985889,-0.4918385618163464,-0.015734964198557747,-0.8531472312752075,1.573819316272094,-0.24461259530598548,-0.3523723803792923,-1.3357688144594548,0.13535733730271166,-0.44523349939724377,3.502130832268083,-0.04609484197467206,-0.07650252744056436,-0.32152087180770866,-0.44523349939724377,-0.44523349939724377,0.2703536119434672,0.6112661660954188,-0.3987451465185144,0.4044403103634737,-1.4011564023133367,0.10523221520582753,0.13535733730271166,2.725031627796951,1.5034435722199273,0.0297158455536117,-0.22926842223566576,1.062010089223635,0.3598443506231174,-0.06129269053099454,-0.3678171946564402,-0.00057286259791032,-0.3678171946564402,0.6112661660954188,-0.5697761307887955,-0.7897895963070047,1.1194765902923671,2.428913363747869,0.07506070309973252,0.8014705690921952,0.1954695077304166,0.13535733730271166,0.888674836109678,-0.6794490424983824,-0.00057286259791032,0.7139008185990915,-0.522974005179062,0.9466108546188425,0.8451180196791206,1.4328440873723212,-0.5073997148873077,0.5228837222779321,0.044842523349634685,0.6112661660954188,0.6259595854721536,0.2852966167197613,-0.2907199213981397,-0.25996921007055324,1.0763911704719784,0.0297158455536117,0.1954695077304166,0.13535733730271166,0.4933376536617622,-0.32152087180770866,-0.5697761307887955,-0.6480464817522166,-0.07650252744056436,-0.30611409685763147,3.8628534229832154,-0.710906100634738,1.8114594151764092,0.12030055776561276,0.6992699083324146,-0.2907199213981397,1.6299606471660821,0.7139008185990915,0.37472066384711566,-0.710906100634738,-0.00057286259791032,2.644629964151358,-0.3678171946564402,-0.3369402862428846,0.16543634416126807,1.2482182125944992,0.5671226765594547,0.3449570020292946,1.0907625977334081 | 3,392 |
Response to reactive oxygen species | 7 | 33 | 2.798351 | 0.005136 | P00374,P09493,P09601,P31749,P23396,O95831,P04083 | Processes and pathways | GO Biological process | msigdb_gobp | 4,105,10,23,217,30,190 | 312,30,4,190,3274,796,105,10,1489,1402,217,1322,1295,2063,2734,2441,2458,23,1886,2735,788,2857,2577,2382,861,2604,1865,1984,2356,2762,1034,2900,1749 | 1.262475712405316,3.37208282113663,4.25660783544249,1.6299606471660821,-1.4011564023133367,0.4933376536617622,2.1701960548718655,3.9012117159107698,-0.015734964198557747,0.0297158455536117,1.5316205651807586,0.07506070309973252,0.09015227518848501,-0.32152087180770866,-0.710906100634738,-0.5073997148873077,-0.522974005179062,3.502130832268083,-0.22926842223566576,-0.710906100634738,0.5081160512050436,-0.8056079589553966,-0.6010440292225467,-0.47629050319229616,0.4341161923697676,-0.6166980548909288,-0.21393665194747497,-0.2753383056546045,-0.46075549648323305,-0.726655180985889,0.3002284258115414,-0.8214403202477919,-0.15273282774028654 | 3,392 |
Visual field defect | 13 | 47 | 2.796201 | 0.005171 | O75381,P00846,Q9Y5Y5,O75306,Q9H061,P03886,P00403,P56589,P31749,Q9Y287,Q9H6K4,P40855,O15460 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 280,33,130,417,12,220,92,464,23,414,156,93,407 | 1828,407,873,2693,707,417,280,2266,2336,92,33,1022,220,2715,2372,3149,2195,2748,1492,2114,2309,23,1595,2310,93,1235,1271,1236,1272,2199,1094,2034,464,800,504,2556,1986,2706,1509,699,682,1960,2656,12,156,414,130 | -0.19861724574074396,1.062010089223635,0.4192837063531287,-0.6794490424983824,0.596562227640058,1.0476193288474605,1.3336236238545365,-0.4297244698805092,-0.46075549648323305,2.2930986183056987,3.2806564295146425,0.3002284258115414,1.5175365324543044,-0.6951707365076549,-0.47629050319229616,-1.0767020329756654,-0.3987451465185144,-0.726655180985889,-0.015734964198557747,-0.3523723803792923,-0.44523349939724377,3.502130832268083,-0.07650252744056436,-0.44523349939724377,2.2930986183056987,0.13535733730271166,0.10523221520582753,0.13535733730271166,0.10523221520582753,-0.3987451465185144,0.24043388497129026,-0.30611409685763147,0.9466108546188425,0.4933376536617622,0.888674836109678,-0.5854034026110678,-0.2753383056546045,-0.6794490424983824,-0.015734964198557747,0.6112661660954188,0.6259595854721536,-0.25996921007055324,-0.6480464817522166,3.8628534229832154,1.8114594151764092,1.062010089223635,1.936269398935176 | 3,392 |
Signaling by notch | 14 | 61 | 2.792478 | 0.005231 | Q9UL46,O00231,Q15363,Q9HCE1,P28072,P28070,Q9UBV2,P49721,P20618,P67809,P61289,P31749,Q06323,Q11206 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,386,230,164,227,335,75,236,271,116,23,121,353 | 193,3012,1878,872,1621,1396,1701,1939,948,1116,1230,236,929,1231,1832,1659,2168,227,164,1145,23,1805,788,759,2169,445,75,1211,1299,1096,116,889,2141,1836,3356,634,1837,271,121,353,2007,1382,3081,1684,1353,386,3140,1782,2794,2418,2356,1692,825,1962,655,1930,230,335,64,1390,2495 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,-0.25996921007055324,0.3598443506231174,0.22545709717825904,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,3.502130832268083,-0.18331016512462858,0.5081160512050436,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-2.15537968959048,0.6992699083324146,-0.19861724574074396,1.362018084052379,2.0191011953082207,1.1910943651123755,-0.2907199213981397,0.044842523349634685,-0.9965341580527574,-0.12220433600304552,0.0599574641453926,1.1051243960353279,-1.0606389558982219,-0.1680153718164889,-0.7581946761452075,-0.4918385618163464,-0.46075549648323305,-0.12220433600304552,0.47854849943901234,-0.25996921007055324,0.6846286512595186,-0.24461259530598548,1.5034435722199273,1.233951351838413,2.671459958677549,0.044842523349634685,-0.5385614757094254 | 3,392 |
Hedgehog ligand biogenesis | 9 | 42 | 2.791358 | 0.005249 | Q9UL46,O00231,P28072,P28070,Q9UBV2,P49721,P20618,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,335,75,236,116,121 | 193,3012,1878,872,1621,1396,1701,1113,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1461,1096,116,889,2141,1836,121,2007,1275,2888,1353,2794,825,1962,335,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.22545709717825904,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,-0.00057286259791032,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,0.10523221520582753,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,1.233951351838413,2.671459958677549,0.044842523349634685 | 3,392 |
Lytic vacuole organization | 6 | 27 | 2.785151 | 0.00535 | P04062,Q14108,O14773,Q9P253,P50897,Q9NWW5 | Processes and pathways | GO Biological process | msigdb_gobp | 32,74,140,142,55,118 | 2876,140,632,429,32,2269,573,558,2002,55,1768,154,1042,1600,74,912,1135,1848,2288,1200,1020,2078,1851,118,142,2938,716 | -0.8214403202477919,1.8808822458505576,0.6992699083324146,1.0332188640882995,3.2937373551059523,-0.4297244698805092,0.7869011513881382,0.8160298348526115,-0.2907199213981397,2.725031627796951,-0.1680153718164889,1.8114594151764092,0.2852966167197613,-0.07650252744056436,2.5370126379799847,0.38958597328502204,0.21046898250401078,-0.19861724574074396,-0.4297244698805092,0.16543634416126807,0.31514907160504646,-0.32152087180770866,-0.19861724574074396,2.0328776982252563,1.8808822458505576,-0.8531472312752075,0.596562227640058 | 3,392 |
Abnormal vascular physiology | 17 | 55 | 2.775572 | 0.00551 | P04062,Q9NZ08,Q9Y4P3,P20674,Q14108,P22413,P21359,O75844,Q9NWM8,Q8IZA0,P00403,P31749,Q8NFV4,P03886,Q15056,Q9Y4U1,O15460 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,191,512,358,74,472,204,50,340,355,92,23,440,220,253,325,407 | 2854,407,1252,1855,3196,1758,50,3103,795,92,1022,844,220,32,1939,513,601,2643,358,2923,204,472,2644,3189,1438,23,1595,649,788,2198,1271,1406,1026,2649,2445,2835,74,2951,1133,253,1578,790,1445,355,440,1640,1848,2615,340,191,2975,2920,1798,512,325 | -0.8056079589553966,1.062010089223635,0.12030055776561276,-0.21393665194747497,-1.141103441123685,-0.1680153718164889,2.8318251529978857,-1.0285571596923793,0.4933376536617622,2.2930986183056987,0.3002284258115414,0.4489377993753778,1.5175365324543044,3.2937373551059523,-0.25996921007055324,0.8741659228684505,0.7431317115189636,-0.6480464817522166,1.1767898212573111,-0.8531472312752075,1.573819316272094,0.9321417422805507,-0.6480464817522166,-1.1249806168260381,0.014577395414097777,3.502130832268083,-0.07650252744056436,0.6846286512595186,0.5081160512050436,-0.3987451465185144,0.10523221520582753,0.0297158455536117,0.3002284258115414,-0.6480464817522166,-0.5073997148873077,-0.7897895963070047,2.5370126379799847,-0.8690218779880967,0.21046898250401078,1.4186970981267617,-0.06129269053099454,0.5081160512050436,0.014577395414097777,1.1910943651123755,1.0043887198247081,-0.09172438937674851,-0.19861724574074396,-0.6166980548909288,1.2196751063114128,1.6299606471660821,-0.8849107173056833,-0.8372867282398355,-0.1680153718164889,0.888674836109678,1.2482182125944992 | 3,392 |
Pten regulation | 10 | 70 | 2.775369 | 0.005514 | Q9UL46,O00231,Q9HCE1,P28072,P31751,P28070,P49721,P61289,P31749,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,230,164,101,227,75,116,23,121 | 193,3012,1878,872,1621,1396,2664,1701,2370,1545,1939,2231,1230,949,236,929,1231,1832,1659,1322,2168,227,164,1145,2063,23,101,1805,2002,759,585,2169,445,75,1211,1299,1096,116,889,2141,1836,1379,2201,121,1773,3080,2007,2090,1382,2461,2888,1353,1983,1838,912,2211,2414,1744,2794,2356,1473,825,1962,2874,230,1722,64,1875,1390,1565 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.6637409727699075,-0.13746249502499586,-0.47629050319229616,-0.04609484197467206,-0.25996921007055324,-0.4142283661153823,0.13535733730271166,0.3598443506231174,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,0.07506070309973252,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.32152087180770866,3.502130832268083,2.197563227073385,-0.18331016512462858,-0.2907199213981397,0.5376406969420575,0.7723215542957492,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,0.044842523349634685,-0.3987451465185144,2.0191011953082207,-0.1680153718164889,-0.9965341580527574,-0.2907199213981397,-0.3369402862428846,0.044842523349634685,-0.522974005179062,-0.8214403202477919,0.0599574641453926,-0.2753383056546045,-0.19861724574074396,0.38958597328502204,-0.3987451465185144,-0.4918385618163464,-0.15273282774028654,-0.7581946761452075,-0.46075549648323305,-0.00057286259791032,0.47854849943901234,-0.25996921007055324,-0.8056079589553966,1.5034435722199273,-0.13746249502499586,2.671459958677549,-0.21393665194747497,0.044842523349634685,-0.04609484197467206 | 3,392 |
Impaired proprioception | 8 | 42 | 2.769933 | 0.005607 | P00846,Q8IV08,O14773,Q9NR77,Q9Y619,P54802,Q9H6K4,Q9Y6B6 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 33,37,140,108,87,154,156,158 | 140,2456,2132,2304,385,1593,2336,33,2110,178,2028,2716,2748,1057,758,2442,2905,953,154,1706,1461,1630,2835,983,1600,2202,1354,3095,3043,792,37,2467,1959,1961,1284,156,867,108,1875,87,158,2496 | 1.8808822458505576,-0.522974005179062,-0.3678171946564402,-0.44523349939724377,1.1051243960353279,-0.07650252744056436,-0.46075549648323305,3.2806564295146425,-0.3523723803792923,1.6859618908518097,-0.30611409685763147,-0.6951707365076549,-0.726655180985889,0.2703536119434672,0.5376406969420575,-0.5073997148873077,-0.8372867282398355,0.3598443506231174,1.8114594151764092,-0.13746249502499586,-0.00057286259791032,-0.09172438937674851,-0.7897895963070047,0.3449570020292946,-0.07650252744056436,-0.3987451465185144,0.0599574641453926,-1.0125383355924664,-0.9486089895638056,0.5081160512050436,3.175766480827432,-0.522974005179062,-0.25996921007055324,-0.25996921007055324,0.10523221520582753,1.8114594151764092,0.4341161923697676,2.1153656498312228,-0.21393665194747497,2.4018122550596814,1.8114594151764092,-0.5385614757094254 | 3,392 |
transporter | 11 | 57 | 2.765331 | 0.005687 | Q567V2,O43615,Q8N8Q8,Q99595,Q8N1F7,O60830,Q9NR77,Q9H2D1,Q15070,Q9Y619,Q9HD45 | Functions | Panther Protein class | panther_protein_class | 96,66,291,6,331,9,108,15,81,87,287 | 1588,2365,2826,2303,1395,66,523,2663,691,1907,9,2976,1594,1234,952,2905,1375,3219,2004,2313,1807,2648,2005,710,1378,2834,2240,2509,81,96,864,331,3023,291,391,2353,641,1611,1335,1474,1693,1387,6,2183,1928,2586,668,15,3293,1789,287,108,2022,3100,1999,1566,87 | -0.07650252744056436,-0.47629050319229616,-0.7897895963070047,-0.44523349939724377,0.0297158455536117,2.644629964151358,0.8596469929949846,-0.6637409727699075,0.6112661660954188,-0.24461259530598548,3.9522705239894336,-0.900813798450678,-0.07650252744056436,0.13535733730271166,0.3598443506231174,-0.8372867282398355,0.044842523349634685,-1.2057460042171027,-0.2907199213981397,-0.44523349939724377,-0.18331016512462858,-0.6480464817522166,-0.2907199213981397,0.596562227640058,0.044842523349634685,-0.7897895963070047,-0.4142283661153823,-0.5541621697421181,2.442452416251786,2.279474345538932,0.4341161923697676,1.233951351838413,-0.9326628846066711,1.3194125750424903,1.0907625977334081,-0.46075549648323305,0.6992699083324146,-0.07650252744056436,0.07506070309973252,-0.00057286259791032,-0.12220433600304552,0.044842523349634685,4.1048668927725505,-0.3832747697389823,-0.24461259530598548,-0.6010440292225467,0.6699770190108111,3.760293155258865,-1.483251123536119,-0.1680153718164889,1.3336236238545365,2.1153656498312228,-0.2907199213981397,-1.0125383355924664,-0.2753383056546045,-0.04609484197467206,2.4018122550596814 | 3,392 |
Uch proteinases | 8 | 48 | 2.763791 | 0.005713 | Q9UL46,O00231,P28072,P28070,P49721,Q8NB78,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,45,116,121 | 193,3012,1878,872,1621,2713,1396,1701,1974,1230,236,1733,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,2832,1211,1299,1096,116,889,2141,1836,3065,121,2007,2888,1353,1985,45,2794,825,1962,64,1390,782,1392,1249 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,-0.6951707365076549,0.0297158455536117,-0.13746249502499586,-0.2753383056546045,0.13535733730271166,1.4752307813901213,-0.15273282774028654,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,-0.7897895963070047,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.9805445753920402,2.0191011953082207,-0.2907199213981397,-0.8214403202477919,0.0599574641453926,-0.2753383056546045,2.991155417180416,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,0.5228837222779321,0.044842523349634685,0.13535733730271166 | 3,392 |
Cation transmembrane transport | 32 | 130 | 2.752104 | 0.005921 | P05067,Q8N4V1,P61421,P47985,P62258,P00846,O75027,Q70HW3,Q9HD20,P35670,Q6KCM7,Q96GC9,P21796,P08195,Q13423,O75964,Q7KZN9,Q9NWR8,P11413,Q9UDW1,P24539,Q9Y619,P06576,Q04917,P36543,P00403,Q8IYU8,P20674,Q8TAD4,Q8NEW0,Q9H4I9,P27105 | Processes and pathways | GO Biological process | msigdb_gobp | 513,529,526,537,283,33,39,44,176,430,562,186,69,71,588,73,329,207,337,82,463,87,214,474,473,92,485,358,110,109,380,376 | 2903,852,771,2663,1972,39,2569,996,1857,784,73,1518,1253,92,33,1730,2229,513,2571,2457,214,2502,3076,1431,1432,71,1185,2543,2196,337,997,876,1116,2787,3204,1658,358,950,3347,2923,69,1118,463,2644,376,1295,1628,1979,2458,786,1551,1980,430,2403,1860,473,2236,585,2139,537,3035,878,1679,2481,2979,1256,2237,1982,526,2834,283,819,2314,2579,1681,1770,861,474,983,2446,3221,1302,933,588,1352,2242,2386,562,863,44,329,2285,485,2684,529,1687,109,110,1719,1472,2179,749,2779,186,2217,1083,2762,1788,2289,2492,702,2614,380,991,1104,1020,2473,176,867,2427,207,82,1481,2398,1999,2329,2056,739,87,1567 | -0.8372867282398355,0.4341161923697676,0.5228837222779321,-0.6637409727699075,-0.2753383056546045,3.136320692524441,-0.6010440292225467,0.3300585863237035,-0.21393665194747497,0.5081160512050436,2.563961827278685,-0.030908945292574343,0.12030055776561276,2.2930986183056987,3.2806564295146425,-0.15273282774028654,-0.4142283661153823,0.8741659228684505,-0.6010440292225467,-0.522974005179062,1.5316205651807586,-0.5541621697421181,-0.9965341580527574,0.014577395414097777,0.014577395414097777,2.5774251672985713,0.16543634416126807,-0.5854034026110678,-0.3987451465185144,1.2196751063114128,0.3300585863237035,0.4192837063531287,0.22545709717825904,-0.7581946761452075,-1.1572413371765422,-0.1069583132087397,1.1767898212573111,0.3598443506231174,-2.018657093338504,-0.8531472312752075,2.6043294186857167,0.22545709717825904,0.9466108546188425,-0.6480464817522166,1.1194765902923671,0.09015227518848501,-0.09172438937674851,-0.2753383056546045,-0.522974005179062,0.5081160512050436,-0.04609484197467206,-0.2753383056546045,1.0332188640882995,-0.4918385618163464,-0.21393665194747497,0.9321417422805507,-0.4142283661153823,0.7723215542957492,-0.3678171946564402,0.8451180196791206,-0.9486089895638056,0.4192837063531287,-0.12220433600304552,-0.5385614757094254,-0.900813798450678,0.12030055776561276,-0.4142283661153823,-0.2753383056546045,0.8596469929949846,-0.7897895963070047,1.3336236238545365,0.47854849943901234,-0.44523349939724377,-0.6010440292225467,-0.12220433600304552,-0.1680153718164889,0.4341161923697676,0.9321417422805507,0.3449570020292946,-0.5073997148873077,-1.2057460042171027,0.09015227518848501,0.37472066384711566,0.7723215542957492,0.0599574641453926,-0.4142283661153823,-0.47629050319229616,0.8160298348526115,0.4341161923697676,3.0043870268143222,1.233951351838413,-0.4297244698805092,0.9176627193149094,-0.6637409727699075,0.8596469929949846,-0.12220433600304552,2.1016379298886707,2.1016379298886707,-0.13746249502499586,-0.00057286259791032,-0.3832747697389823,0.5523870051126312,-0.7424180239388641,1.6439740384202233,-0.3987451465185144,0.2553993789324403,-0.726655180985889,-0.1680153718164889,-0.4297244698805092,-0.5385614757094254,0.6112661660954188,-0.6166980548909288,1.1194765902923671,0.3449570020292946,0.24043388497129026,0.31514907160504646,-0.522974005179062,1.6999404710130017,0.4341161923697676,-0.4918385618163464,1.573819316272094,2.442452416251786,-0.00057286259791032,-0.47629050319229616,-0.2753383056546045,-0.44523349939724377,-0.30611409685763147,0.5671226765594547,2.4018122550596814,-0.04609484197467206 | 3,392 |
Glycoside hydrolase superfamily [IPR017853] | 9 | 18 | 2.74041 | 0.006136 | P04062,P10253,P06280,P04066,P08195,P54802,P08236,O60502,P06865 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 32,573,601,418,71,154,514,170,215 | 1675,170,32,418,601,215,2269,71,514,573,1144,1128,154,891,982,2008,722,1313 | -0.12220433600304552,1.71391040052824,3.2937373551059523,1.0476193288474605,0.7431317115189636,1.5316205651807586,-0.4297244698805092,2.5774251672985713,0.8741659228684505,0.7869011513881382,0.1954695077304166,0.21046898250401078,1.8114594151764092,0.4044403103634737,0.3449570020292946,-0.2907199213981397,0.5818477409079303,0.09015227518848501 | 3,392 |
Progressive visual loss | 6 | 25 | 2.737118 | 0.006198 | P00846,P21359,O14773,P50897,P31749,Q9NWW5 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 33,204,140,55,23,118 | 1828,140,645,707,417,632,2336,33,220,2715,1940,2643,204,23,1595,2310,55,2120,2241,1240,2125,1509,1960,2957,118 | -0.19861724574074396,1.8808822458505576,0.6846286512595186,0.596562227640058,1.0476193288474605,0.6992699083324146,-0.46075549648323305,3.2806564295146425,1.5175365324543044,-0.6951707365076549,-0.25996921007055324,-0.6480464817522166,1.573819316272094,3.502130832268083,-0.07650252744056436,-0.44523349939724377,2.725031627796951,-0.3523723803792923,-0.4142283661153823,0.13535733730271166,-0.3523723803792923,-0.015734964198557747,-0.25996921007055324,-0.8690218779880967,2.0328776982252563 | 3,392 |
Fceri mediated nf kb activation | 8 | 44 | 2.730331 | 0.006327 | Q9UL46,O00231,P28072,P28070,P49721,P20618,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,236,116,121 | 193,3012,1878,872,1621,312,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,1001,116,889,2141,1836,1837,121,2007,1684,2888,1353,1867,2794,825,1962,64,1390,1697 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,1.262475712405316,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,0.3300585863237035,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.12220433600304552,-0.8214403202477919,0.0599574641453926,-0.21393665194747497,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,-0.12220433600304552 | 3,392 |
Golgi stack | 11 | 38 | 2.727803 | 0.006376 | Q11206,Q15363,Q9Y3A3,Q8NBZ7,Q8TBA6,Q8NBN3,Q10713,O00461,Q08378,Q8WVQ1,Q9Y6B6 | Localization | GO Cellular component | msigdb_gocc | 353,386,98,134,172,113,83,276,352,322,158 | 276,1568,618,1856,772,2372,2135,948,2506,3238,1042,2579,2529,352,1682,1098,450,83,353,2530,1044,2242,386,1604,113,134,172,1414,322,1336,989,1963,1200,869,1515,2189,98,158 | 1.3478254524900601,-0.06129269053099454,0.7139008185990915,-0.21393665194747497,0.5228837222779321,-0.47629050319229616,-0.3678171946564402,0.3598443506231174,-0.5541621697421181,-1.2706332542898442,0.2852966167197613,-0.6010440292225467,-0.5697761307887955,1.1910943651123755,-0.12220433600304552,0.24043388497129026,0.9755194520783873,2.428913363747869,1.1910943651123755,-0.5697761307887955,0.2852966167197613,-0.4142283661153823,1.1051243960353279,-0.07650252744056436,2.074158219188792,1.9085925209979264,1.71391040052824,0.0297158455536117,1.2482182125944992,0.07506070309973252,0.3449570020292946,-0.25996921007055324,0.16543634416126807,0.4341161923697676,-0.015734964198557747,-0.3832747697389823,2.2522022302138622,1.8114594151764092 | 3,392 |
Apoptosis | 35 | 125 | 2.726509 | 0.006401 | Q9P0J0,Q9H2J4,P09601,P05067,O95197,P31749,Q8N163,Q9UDX5,O95831,Q9NXR7,Q9BX68,O75414,O60333,Q9H3K2,Q96A26,O75940,Q96KA5,Q9BY67,Q9UHX1,P46379,P21796,O43464,Q9Y3D6,Q9NR28,Q9Y255,Q16539,P23396,O14737,Q14728,Q8WYA6,P31751,P61289,P52756,Q15041,Q07021 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 522,138,10,513,141,23,279,29,30,294,554,546,169,310,58,313,442,443,67,319,69,203,469,209,598,343,217,341,475,604,101,116,502,248,378 | 2433,1266,341,2713,1163,203,2367,707,169,1428,1829,546,1701,313,2336,141,2501,1269,2746,30,3370,2268,2641,1939,513,796,10,1143,1549,949,69,217,1322,2063,2458,1040,23,101,2857,1350,319,2860,3238,502,979,1443,116,3382,1326,2577,2201,1770,860,3220,2604,378,2446,1029,2144,2174,717,2998,1274,697,745,1504,2069,2531,475,248,1150,1778,1013,343,2042,2283,1898,2389,1446,3241,2813,279,1334,1819,604,3003,2287,58,1311,1535,2217,1692,442,713,3057,554,443,1583,3071,2613,138,310,770,1561,1790,2658,209,2900,294,631,522,29,2798,67,3161,2785,1482,598,1223,3162,1265,469,2921,716,3087 | -0.5073997148873077,0.10523221520582753,1.205389452082045,-0.6951707365076549,0.18045863946931265,1.573819316272094,-0.47629050319229616,0.596562227640058,1.71391040052824,0.014577395414097777,-0.19861724574074396,0.8305789759854734,-0.13746249502499586,1.262475712405316,-0.46075549648323305,1.8808822458505576,-0.5541621697421181,0.10523221520582753,-0.726655180985889,3.37208282113663,-2.5907524840201,-0.4297244698805092,-0.6480464817522166,-0.25996921007055324,0.8741659228684505,0.4933376536617622,3.9012117159107698,0.1954695077304166,-0.04609484197467206,0.3598443506231174,2.6043294186857167,1.5316205651807586,0.07506070309973252,-0.32152087180770866,-0.522974005179062,0.2852966167197613,3.502130832268083,2.197563227073385,-0.8056079589553966,0.0599574641453926,1.2482182125944992,-0.8056079589553966,-1.2706332542898442,0.888674836109678,0.3449570020292946,0.014577395414097777,2.046646024024901,-3.9067082862563556,0.07506070309973252,-0.6010440292225467,-0.3987451465185144,-0.1680153718164889,0.4341161923697676,-1.2057460042171027,-0.6166980548909288,1.1194765902923671,-0.5073997148873077,0.3002284258115414,-0.3678171946564402,-0.3832747697389823,0.5818477409079303,-0.9167311709438607,0.10523221520582753,0.6112661660954188,0.5523870051126312,-0.015734964198557747,-0.32152087180770866,-0.5697761307887955,0.9321417422805507,1.4328440873723212,0.1954695077304166,-0.1680153718164889,0.31514907160504646,1.205389452082045,-0.30611409685763147,-0.4297244698805092,-0.22926842223566576,-0.47629050319229616,0.014577395414097777,-1.2706332542898442,-0.7739851845325647,1.3478254524900601,0.07506070309973252,-0.18331016512462858,0.7431317115189636,-0.9167311709438607,-0.4297244698805092,2.711649711497065,0.09015227518848501,-0.030908945292574343,-0.3987451465185144,-0.12220433600304552,1.0043887198247081,0.596562227640058,-0.9645695362458719,0.8305789759854734,1.0043887198247081,-0.06129269053099454,-0.9805445753920402,-0.6166980548909288,1.8947415678252209,1.2767238749913556,0.5376406969420575,-0.04609484197467206,-0.1680153718164889,-0.6480464817522166,1.5597619353863794,-0.8214403202477919,1.3194125750424903,0.7139008185990915,0.8741659228684505,3.3851171733169934,-0.7581946761452075,2.644629964151358,-1.0767020329756654,-0.7424180239388641,-0.00057286259791032,0.7577317502408601,0.1504025880743201,-1.0767020329756654,0.12030055776561276,0.9466108546188425,-0.8372867282398355,0.596562227640058,-0.9965341580527574 | 3,392 |
Transcriptional regulation by runx3 | 7 | 43 | 2.72317 | 0.006466 | Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,116,121 | 193,3012,1878,872,1621,1396,1701,1939,1230,236,1434,929,1231,1832,1659,2168,227,164,1145,1595,1805,835,759,2169,445,75,1211,1299,1096,116,889,2141,1836,121,2007,3081,1602,1353,2794,825,1962,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,-0.25996921007055324,0.13535733730271166,1.4752307813901213,0.014577395414097777,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.07650252744056436,-0.18331016512462858,0.4637485581792443,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.9965341580527574,-0.07650252744056436,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685 | 3,392 |
Mapk family signaling cascades | 15 | 91 | 2.720269 | 0.006523 | Q9UL46,Q14168,Q13555,O00231,P28072,Q9HCE1,P28070,P49721,P21359,P20618,P07196,O60725,P61289,Q06323,Q16181 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,97,34,193,164,230,227,75,204,236,178,84,116,121,126 | 193,3012,1878,1318,872,1621,2303,2132,1396,84,2107,1701,796,178,1520,2787,1230,2524,236,204,1435,929,1231,1832,1659,1322,2168,227,164,1145,2063,1764,564,262,535,1189,1805,2065,1373,2750,759,1010,2169,2550,445,75,1211,3017,1299,1096,1573,116,3256,889,2141,1836,1554,2142,1381,1862,2006,121,933,1274,2007,3371,34,2720,663,97,2532,2888,1353,2242,126,550,1607,2794,1693,1285,825,1962,685,230,2900,1220,64,1390,1565,1876,1317 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.07506070309973252,0.4192837063531287,-0.09172438937674851,-0.44523349939724377,-0.3678171946564402,0.0297158455536117,2.4153666489525016,-0.3523723803792923,-0.13746249502499586,0.4933376536617622,1.6859618908518097,-0.030908945292574343,-0.7581946761452075,0.13535733730271166,-0.5697761307887955,1.4752307813901213,1.573819316272094,0.014577395414097777,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,0.07506070309973252,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.32152087180770866,-0.1680153718164889,0.8014705690921952,1.3762015415441697,0.8451180196791206,0.16543634416126807,-0.18331016512462858,-0.32152087180770866,0.044842523349634685,-0.726655180985889,0.5376406969420575,0.31514907160504646,-0.3832747697389823,-0.5854034026110678,0.989958989232039,2.5100333281525296,0.1504025880743201,-0.9326628846066711,0.09015227518848501,0.24043388497129026,-0.06129269053099454,2.046646024024901,-1.3357688144594548,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.04609484197467206,-0.3678171946564402,0.044842523349634685,-0.21393665194747497,-0.2907199213981397,2.0191011953082207,0.37472066384711566,0.10523221520582753,-0.2907199213981397,-2.5907524840201,3.2806564295146425,-0.6951707365076549,0.6699770190108111,2.2522022302138622,-0.5697761307887955,-0.8214403202477919,0.0599574641453926,-0.4142283661153823,1.9639130348690015,0.8305789759854734,-0.07650252744056436,-0.7581946761452075,-0.12220433600304552,0.10523221520582753,0.47854849943901234,-0.25996921007055324,0.6259595854721536,1.5034435722199273,-0.8214403202477919,0.1504025880743201,2.671459958677549,0.044842523349634685,-0.04609484197467206,-0.21393665194747497,0.09015227518848501 | 3,392 |
Neuron apoptotic process | 10 | 51 | 2.712342 | 0.006681 | P04062,P31751,P09601,P21359,Q9NR28,P07196,Q01105,P50897,Q96A26,O95831 | Processes and pathways | GO Biological process | msigdb_gobp | 32,101,10,204,209,178,244,55,58,30 | 1089,30,32,3274,2641,1939,513,2110,178,1858,10,2666,337,204,101,1595,2857,1350,1235,1981,574,2198,1376,55,3197,1498,1443,1573,2675,2140,2201,1770,244,982,2446,1029,697,745,956,1778,2418,2512,58,1415,2762,684,1034,2738,209,461,2400 | 0.24043388497129026,3.37208282113663,3.2937373551059523,-1.4011564023133367,-0.6480464817522166,-0.25996921007055324,0.8741659228684505,-0.3523723803792923,1.6859618908518097,-0.21393665194747497,3.9012117159107698,-0.6637409727699075,1.2196751063114128,1.573819316272094,2.197563227073385,-0.07650252744056436,-0.8056079589553966,0.0599574641453926,0.13535733730271166,-0.2753383056546045,0.7869011513881382,-0.3987451465185144,0.044842523349634685,2.725031627796951,-1.141103441123685,-0.015734964198557747,0.014577395414097777,-0.06129269053099454,-0.6637409727699075,-0.3678171946564402,-0.3987451465185144,-0.1680153718164889,1.4469820160729245,0.3449570020292946,-0.5073997148873077,0.3002284258115414,0.6112661660954188,0.5523870051126312,0.3598443506231174,-0.1680153718164889,-0.4918385618163464,-0.5541621697421181,2.711649711497065,0.0297158455536117,-0.726655180985889,0.6259595854721536,0.3002284258115414,-0.710906100634738,1.5597619353863794,0.961070082526128,-0.47629050319229616 | 3,392 |
Regulation of runx2 expression and activity | 7 | 43 | 2.712259 | 0.006683 | Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,116,121 | 193,3012,1878,872,1621,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,788,759,2169,445,75,1211,1299,1096,116,889,2141,1836,1837,121,2007,1684,1602,2888,1353,2794,825,1962,64,1875,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5081160512050436,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.12220433600304552,-0.07650252744056436,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,-0.21393665194747497,0.044842523349634685 | 3,392 |
Proteasome degradation | 7 | 42 | 2.71132 | 0.006702 | Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323 | Processes and pathways | WikiPathways | msigdb_wp | 64,193,164,227,75,116,121 | 193,3012,1878,1621,1396,1701,1022,2372,1399,2597,1270,1230,236,2696,929,1231,1832,1659,2168,227,164,1145,1805,759,585,2169,445,75,1211,1299,1096,116,889,2141,1836,121,2007,1353,825,1962,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.3002284258115414,-0.47629050319229616,0.0297158455536117,-0.6166980548909288,0.10523221520582753,0.13535733730271166,1.4752307813901213,-0.6794490424983824,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,0.7723215542957492,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,0.0599574641453926,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685 | 3,392 |
Bulbar signs | 9 | 12 | 2.70578 | 0.006814 | P04062,P00846,P06753,Q9NZJ7,P35637,Q92734,O43681,P07602,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,33,610,631,263,467,523,117,220 | 523,33,220,32,610,117,263,886,467,1034,631,644 | 0.8596469929949846,3.2806564295146425,1.5175365324543044,3.2937373551059523,0.7285214102943242,2.0328776982252563,1.3762015415441697,0.4044403103634737,0.9466108546188425,0.3002284258115414,0.7139008185990915,0.6992699083324146 | 3,392 |
Parkinsons disease | 19 | 62 | 2.702778 | 0.006876 | Q9Y6M9,O43674,Q99643,O14949,P14406,P00846,O43676,P60604,O75306,P21796,O43464,P24539,Q9UDW1,P06576,P03886,P00403,P20674,P45880,P22695 | Processes and pathways | KEGG Pathways | msigdb_kegg | 394,389,530,18,282,33,38,168,417,69,203,463,82,214,220,92,358,102,106 | 2191,2903,852,2520,18,203,389,38,3195,2855,2569,417,924,784,2161,973,2500,1544,795,92,33,220,2571,214,1185,2307,2196,997,1549,876,282,3295,1656,2402,358,69,1909,2696,106,463,2644,3255,1979,2309,1980,1860,2857,102,537,3035,3275,1026,168,879,2144,1277,2534,2762,530,82,1905,394 | -0.3987451465185144,-0.8372867282398355,0.4341161923697676,-0.5697761307887955,3.6444348969265956,1.573819316272094,1.0907625977334081,3.149476125453242,-1.141103441123685,-0.8056079589553966,-0.6010440292225467,1.0476193288474605,0.37472066384711566,0.5081160512050436,-0.3832747697389823,0.3449570020292946,-0.5541621697421181,-0.04609484197467206,0.4933376536617622,2.2930986183056987,3.2806564295146425,1.5175365324543044,-0.6010440292225467,1.5316205651807586,0.16543634416126807,-0.44523349939724377,-0.3987451465185144,0.3300585863237035,-0.04609484197467206,0.4192837063531287,1.3336236238545365,-1.4997187103625877,-0.1069583132087397,-0.4918385618163464,1.1767898212573111,2.6043294186857167,-0.24461259530598548,-0.6794490424983824,2.1427969107941136,0.9466108546188425,-0.6480464817522166,-1.3357688144594548,-0.2753383056546045,-0.44523349939724377,-0.2753383056546045,-0.21393665194747497,-0.8056079589553966,2.197563227073385,0.8451180196791206,-0.9486089895638056,-1.4011564023133367,0.3002284258115414,1.7278717000747983,0.4192837063531287,-0.3678171946564402,0.10523221520582753,-0.5697761307887955,-0.726655180985889,0.8596469929949846,2.442452416251786,-0.22926842223566576,1.0907625977334081 | 3,392 |
Abc transporter disorders | 9 | 43 | 2.702569 | 0.006881 | Q9UL46,O00231,P28072,P28070,Q9UBV2,P49721,P20618,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,335,75,236,116,121 | 193,3012,1878,872,1621,1396,1701,1593,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1461,1096,116,889,2141,1836,121,2007,1275,2888,1353,2794,825,1962,654,335,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,-0.07650252744056436,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,-0.00057286259791032,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,0.10523221520582753,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,0.6846286512595186,1.233951351838413,2.671459958677549,0.044842523349634685 | 3,392 |
Defective cftr causes cystic fibrosis | 9 | 43 | 2.702569 | 0.006881 | Q9UL46,O00231,P28072,P28070,Q9UBV2,P49721,P20618,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,335,75,236,116,121 | 193,3012,1878,872,1621,1396,1701,1593,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1461,1096,116,889,2141,1836,121,2007,1275,2888,1353,2794,825,1962,654,335,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,-0.07650252744056436,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,-0.00057286259791032,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,0.10523221520582753,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,0.6846286512595186,1.233951351838413,2.671459958677549,0.044842523349634685 | 3,392 |
Degradation of dvl | 7 | 39 | 2.689572 | 0.007154 | Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,193,164,227,75,116,121 | 193,3012,1878,872,1621,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,121,2007,2720,2888,1353,2794,825,1962,64,1390 | 1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.6951707365076549,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685 | 3,392 |
Wide anterior fontanel | 13 | 28 | 2.685668 | 0.007238 | O75381,Q9Y5Y5,O75718,P20674,Q08J23,Q9Y487,Q15436,P56589,Q32P28,O15111,Q2M1P5,P40855,Q9H9E3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 280,130,454,358,361,235,435,464,249,312,354,93,356 | 312,280,2438,454,2623,516,358,2923,2698,3175,93,2002,1272,464,2120,361,2532,2722,435,1466,354,249,1445,1640,3056,356,235,130 | 1.262475712405316,1.3336236238545365,-0.5073997148873077,0.961070082526128,-0.6323655241400963,0.8741659228684505,1.1767898212573111,-0.8531472312752075,-0.6794490424983824,-1.1088728099650214,2.2930986183056987,-0.2907199213981397,0.10523221520582753,0.9466108546188425,-0.3523723803792923,1.162475796263921,-0.5697761307887955,-0.6951707365076549,1.018808669576008,-0.00057286259791032,1.1910943651123755,1.4328440873723212,0.014577395414097777,-0.09172438937674851,-0.9645695362458719,1.1910943651123755,1.4893416625418183,1.936269398935176 | 3,392 |
Organic acid transmembrane transport | 7 | 33 | 2.685201 | 0.007249 | P31751,P08195,P23786,Q9H2D1,Q9Y619,P31749,Q9UBX3 | Processes and pathways | GO Biological process | msigdb_gobp | 101,71,205,15,87,23,26 | 2663,572,2439,1430,1623,2457,928,71,3378,205,2233,1551,23,101,1571,2905,1093,2648,2005,2120,1661,248,2386,2352,1083,393,15,702,991,1104,26,1342,87 | -0.6637409727699075,0.7869011513881382,-0.5073997148873077,0.014577395414097777,-0.09172438937674851,-0.522974005179062,0.37472066384711566,2.5774251672985713,-3.3346573519697245,1.573819316272094,-0.4142283661153823,-0.04609484197467206,3.502130832268083,2.197563227073385,-0.06129269053099454,-0.8372867282398355,0.24043388497129026,-0.6480464817522166,-0.2907199213981397,-0.3523723803792923,-0.1069583132087397,1.4328440873723212,-0.47629050319229616,-0.46075549648323305,0.2553993789324403,1.0907625977334081,3.760293155258865,0.6112661660954188,0.3449570020292946,0.24043388497129026,3.476173526807814,0.07506070309973252,2.4018122550596814 | 3,392 |
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