term
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overlap
int64
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int64
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499
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float64
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10.6
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float64
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0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
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stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Electron transport chain oxphos system in mitochondria
18
58
2.684854
0.007256
P00846,Q9Y6M9,O43676,P20674,O75964,O43674,O75306,P22695,Q7KZN9,Q99643,O14949,P24539,Q9UDW1,P03886,O75880,P06576,P14406,P00403
Processes and pathways
WikiPathways
msigdb_wp
33,394,38,358,73,389,417,106,329,530,18,463,82,220,462,214,282,92
2191,2903,852,2520,18,389,38,3195,2855,2569,417,924,462,784,73,2161,973,2500,1544,795,92,33,220,2571,214,2307,2196,997,1549,876,282,3295,1656,2402,358,1909,106,463,2644,3255,1979,2309,1980,1860,537,3035,3275,1026,2237,1982,1277,2534,329,530,82,811,394,1108
-0.3987451465185144,-0.8372867282398355,0.4341161923697676,-0.5697761307887955,3.6444348969265956,1.0907625977334081,3.149476125453242,-1.141103441123685,-0.8056079589553966,-0.6010440292225467,1.0476193288474605,0.37472066384711566,0.9466108546188425,0.5081160512050436,2.563961827278685,-0.3832747697389823,0.3449570020292946,-0.5541621697421181,-0.04609484197467206,0.4933376536617622,2.2930986183056987,3.2806564295146425,1.5175365324543044,-0.6010440292225467,1.5316205651807586,-0.44523349939724377,-0.3987451465185144,0.3300585863237035,-0.04609484197467206,0.4192837063531287,1.3336236238545365,-1.4997187103625877,-0.1069583132087397,-0.4918385618163464,1.1767898212573111,-0.24461259530598548,2.1427969107941136,0.9466108546188425,-0.6480464817522166,-1.3357688144594548,-0.2753383056546045,-0.44523349939724377,-0.2753383056546045,-0.21393665194747497,0.8451180196791206,-0.9486089895638056,-1.4011564023133367,0.3002284258115414,-0.4142283661153823,-0.2753383056546045,0.10523221520582753,-0.5697761307887955,1.233951351838413,0.8596469929949846,2.442452416251786,0.4933376536617622,1.0907625977334081,0.24043388497129026
3,392
Outer mitochondrial membrane protein complex
6
16
2.682815
0.007301
Q5XKP0,Q9NS69,Q9Y512,Q8N4H5,Q15388,Q13505
Localization
GO Cellular component
msigdb_gocc
200,42,365,245,342,31
692,1702,1624,2671,31,342,1214,200,2350,1358,245,531,42,1389,868,365
0.6112661660954188,-0.13746249502499586,-0.09172438937674851,-0.6637409727699075,3.359041854851364,1.205389452082045,0.1504025880743201,1.5878678564641069,-0.46075549648323305,0.0599574641453926,1.4469820160729245,0.8596469929949846,3.0704404222415245,0.044842523349634685,0.4341161923697676,1.162475796263921
3,392
Dectin 1 mediated noncanonical nf kb signaling
8
44
2.681143
0.007337
Q9UL46,O00231,P28072,P28070,P49721,P20618,P61289,Q06323
Processes and pathways
Reactome Pathways
msigdb_reactome
64,193,164,227,75,236,116,121
193,3012,1878,872,1621,312,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,2675,116,889,2141,1836,1837,121,2007,1684,2888,1353,1258,2794,825,1962,64,1390,1697
1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,1.262475712405316,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,-0.6637409727699075,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.12220433600304552,-0.8214403202477919,0.0599574641453926,0.12030055776561276,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,-0.12220433600304552
3,392
Tnfr2 non canonical nf kb pathway
8
44
2.681143
0.007337
Q9UL46,O00231,P28072,P28070,P49721,P20618,P61289,Q06323
Processes and pathways
Reactome Pathways
msigdb_reactome
64,193,164,227,75,236,116,121
193,3012,1878,872,1621,312,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,2675,116,889,2141,1836,1837,121,2007,1684,2888,1353,1258,2794,825,1962,64,1390,1697
1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,1.262475712405316,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,-0.6637409727699075,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.12220433600304552,-0.8214403202477919,0.0599574641453926,0.12030055776561276,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,-0.12220433600304552
3,392
Ceramide metabolic process
7
24
2.679283
0.007378
P04062,Q13510,O43464,P17900,Q16739,Q9NWW5,Q96G23
Processes and pathways
GO Biological process
msigdb_gobp
32,132,203,146,112,118,185
1367,903,2594,203,618,1269,32,601,215,2269,146,1493,564,2604,132,112,2811,1813,665,185,2957,2183,118,2566
0.044842523349634685,0.38958597328502204,-0.6166980548909288,1.573819316272094,0.7139008185990915,0.10523221520582753,3.2937373551059523,0.7431317115189636,1.5316205651807586,-0.4297244698805092,1.8531384170199579,-0.015734964198557747,0.8014705690921952,-0.6166980548909288,1.9085925209979264,2.074158219188792,-0.7739851845325647,-0.18331016512462858,0.6699770190108111,1.6439740384202233,-0.8690218779880967,-0.3832747697389823,2.0328776982252563,-0.5854034026110678
3,392
Abnormal retinal artery morphology
13
25
2.677754
0.007412
P00846,P10619,Q13510,Q9NZJ7,P35250,P17900,P07602,Q9Y4P3,Q8NFV4,P06865,P03886,Q15056,P22413
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,35,132,631,649,146,117,512,440,215,220,253,472
1182,873,1252,33,220,215,117,2269,35,2642,1144,146,709,472,649,2971,2445,132,253,440,1745,2957,631,2975,512
0.16543634416126807,0.4192837063531287,0.12030055776561276,3.2806564295146425,1.5175365324543044,1.5316205651807586,2.0328776982252563,-0.4297244698805092,3.2151509431473015,-0.6480464817522166,0.1954695077304166,1.8531384170199579,0.596562227640058,0.9321417422805507,0.6846286512595186,-0.8849107173056833,-0.5073997148873077,1.9085925209979264,1.4186970981267617,1.0043887198247081,-0.15273282774028654,-0.8690218779880967,0.7139008185990915,-0.8849107173056833,0.888674836109678
3,392
Establishment of protein localization to membrane
27
96
2.675985
0.007451
Q9P0J0,Q9Y5Y5,Q9Y5J9,Q8N4V1,Q9UHB9,Q15006,O43681,Q4J6C6,Q8N8Q8,O43765,Q9NS69,Q9HD20,P43307,Q15629,O15027,P46379,Q9Y3D6,Q15070,O60725,P56589,Q9P0I2,O14737,P40855,P31751,Q9Y512,Q15041,P27105
Processes and pathways
GO Biological process
msigdb_gobp
522,130,268,529,404,143,523,155,291,545,42,176,49,59,194,319,469,81,84,464,345,341,93,101,365,248,376
2712,2876,922,341,194,1457,523,545,84,2107,2369,1702,2523,2229,1626,2572,1677,2543,376,1371,1570,101,2235,2505,93,2750,49,319,2506,836,1272,1768,2277,464,2067,3348,2551,1130,2344,2834,2577,2579,1770,1381,2446,1302,566,2123,2984,143,248,1134,81,59,2869,155,732,1813,2283,3379,1278,1384,2212,529,2415,291,1783,1719,822,2288,1536,1200,1019,1643,3338,1159,176,810,1363,1538,42,1339,345,522,1649,404,1481,2103,1934,1826,469,1587,365,3101,268,130
-0.6951707365076549,-0.8214403202477919,0.37472066384711566,1.205389452082045,1.6159385005727454,-0.00057286259791032,0.8596469929949846,0.8305789759854734,2.4153666489525016,-0.3523723803792923,-0.47629050319229616,-0.13746249502499586,-0.5697761307887955,-0.4142283661153823,-0.09172438937674851,-0.6010440292225467,-0.12220433600304552,-0.5854034026110678,1.1194765902923671,0.044842523349634685,-0.06129269053099454,2.197563227073385,-0.4142283661153823,-0.5541621697421181,2.2930986183056987,-0.726655180985889,2.8451418463357636,1.2482182125944992,-0.5541621697421181,0.4637485581792443,0.10523221520582753,-0.1680153718164889,-0.4297244698805092,0.9466108546188425,-0.32152087180770866,-2.035681723950639,-0.5854034026110678,0.21046898250401078,-0.46075549648323305,-0.7897895963070047,-0.6010440292225467,-0.6010440292225467,-0.1680153718164889,0.044842523349634685,-0.5073997148873077,0.09015227518848501,0.8014705690921952,-0.3523723803792923,-0.900813798450678,1.8670145354751024,1.4328440873723212,0.21046898250401078,2.442452416251786,2.6982604715752156,-0.8056079589553966,1.8114594151764092,0.5671226765594547,-0.18331016512462858,-0.4297244698805092,-3.4094648282561173,0.10523221520582753,0.044842523349634685,-0.3987451465185144,0.8596469929949846,-0.4918385618163464,1.3194125750424903,-0.1680153718164889,-0.13746249502499586,0.47854849943901234,-0.4297244698805092,-0.030908945292574343,0.16543634416126807,0.31514907160504646,-0.09172438937674851,-1.8325924202791186,0.1954695077304166,1.6999404710130017,0.4933376536617622,0.0599574641453926,-0.030908945292574343,3.0704404222415245,0.07506070309973252,1.205389452082045,0.8741659228684505,-0.09172438937674851,1.0763911704719784,-0.00057286259791032,-0.3369402862428846,-0.24461259530598548,-0.18331016512462858,0.9466108546188425,-0.06129269053099454,1.162475796263921,-1.0125383355924664,1.3762015415441697,1.936269398935176
3,392
Metabolism of polyamines
7
40
2.674531
0.007483
Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323
Processes and pathways
Reactome Pathways
msigdb_reactome
64,193,164,227,75,116,121
193,3012,1878,872,1621,1396,1701,1230,833,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,2276,1299,1096,116,889,2141,1836,121,2007,2888,1353,2794,825,1962,64,1390
1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,0.4637485581792443,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,-0.4297244698805092,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685
3,392
Skeletal dysplasia
15
48
2.673992
0.007495
O75381,Q9Y5Y5,P10619,P21359,Q96HY6,Q15436,Q15427,P56589,P31749,P40855,P51648,Q2M1P5,Q8WVQ1,O95831,P22413
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
280,130,35,204,432,435,434,464,23,93,27,354,322,30,472
2854,2498,2193,2964,280,30,1113,35,1144,2923,204,472,1859,23,2311,2671,93,1272,27,464,1130,1810,3298,1133,2679,434,435,354,507,1528,1306,2776,322,2816,1848,2655,432,2957,2687,1038,2898,1020,1071,2055,1072,2399,2939,130
-0.8056079589553966,-0.5541621697421181,-0.3987451465185144,-0.8849107173056833,1.3336236238545365,3.37208282113663,0.22545709717825904,3.2151509431473015,0.1954695077304166,-0.8531472312752075,1.573819316272094,0.9321417422805507,-0.21393665194747497,3.502130832268083,-0.44523349939724377,-0.6637409727699075,2.2930986183056987,0.10523221520582753,3.4501901747304498,0.9466108546188425,0.21046898250401078,-0.18331016512462858,-1.5162026565820805,0.21046898250401078,-0.6637409727699075,1.018808669576008,1.018808669576008,1.1910943651123755,0.888674836109678,-0.030908945292574343,0.09015227518848501,-0.7424180239388641,1.2482182125944992,-0.7739851845325647,-0.19861724574074396,-0.6480464817522166,1.0332188640882995,-0.8690218779880967,-0.6637409727699075,0.3002284258115414,-0.8214403202477919,0.31514907160504646,0.2703536119434672,-0.30611409685763147,0.2703536119434672,-0.47629050319229616,-0.8531472312752075,1.936269398935176
3,392
Porphyrin and chlorophyll metabolism
7
14
2.671136
0.007559
P22830,P09601,Q5JPH6,Q7KZN9,P30519,P53701,P36551
Processes and pathways
KEGG Pathways
msigdb_kegg
483,10,237,329,20,411,377
2109,1940,514,1209,10,483,20,377,2884,679,411,237,329,1534
-0.3523723803792923,-0.25996921007055324,0.8741659228684505,0.1504025880743201,3.9012117159107698,0.9176627193149094,3.5669108013937043,1.1194765902923671,-0.8214403202477919,0.6259595854721536,1.062010089223635,1.4752307813901213,1.233951351838413,-0.030908945292574343
3,392
Degradation of gli1 by the proteasome
7
43
2.670531
0.007573
Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323
Processes and pathways
Reactome Pathways
msigdb_reactome
64,193,164,227,75,116,121
193,3012,1878,872,1621,1396,1701,2787,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,1837,121,2007,1684,2888,1353,2794,1692,825,1962,64,1390,1697
1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,-0.7581946761452075,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.12220433600304552,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,-0.12220433600304552,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685,-0.12220433600304552
3,392
Glycosphingolipid metabolism
6
17
2.66994
0.007586
P04062,P10619,Q13510,Q16739,P17900,P07602
Processes and pathways
Reactome Pathways
msigdb_reactome
32,35,132,112,146,117
1541,523,32,601,215,117,2269,35,1144,146,132,112,2811,2957,2819,2566,631
-0.04609484197467206,0.8596469929949846,3.2937373551059523,0.7431317115189636,1.5316205651807586,2.0328776982252563,-0.4297244698805092,3.2151509431473015,0.1954695077304166,1.8531384170199579,1.9085925209979264,2.074158219188792,-0.7739851845325647,-0.8690218779880967,-0.7739851845325647,-0.5854034026110678,0.7139008185990915
3,392
Abnormal retinal vascular morphology
21
56
2.667318
0.007646
Q15555,Q13510,P35250,Q99643,P17900,P00846,P10619,O60333,O75306,Q8WWY3,Q8NFV4,P38435,P21964,P21359,P06865,P03886,P22413,Q9NZJ7,P07602,Q9Y4P3,Q15056
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
504,132,649,530,146,33,35,169,417,682,440,444,709,204,215,220,472,631,117,512,253
3074,1182,706,873,1252,2693,169,417,2965,2266,2786,33,220,2372,215,117,2269,2768,35,1489,2642,1144,146,1492,204,1909,709,472,2309,1595,649,2310,2404,444,2925,1271,1236,2971,2445,1661,132,253,504,2706,440,682,1609,1049,1745,1416,1244,2957,530,631,2975,512
-0.9965341580527574,0.16543634416126807,0.596562227640058,0.4192837063531287,0.12030055776561276,-0.6794490424983824,1.71391040052824,1.0476193288474605,-0.8849107173056833,-0.4297244698805092,-0.7581946761452075,3.2806564295146425,1.5175365324543044,-0.47629050319229616,1.5316205651807586,2.0328776982252563,-0.4297244698805092,-0.7424180239388641,3.2151509431473015,-0.015734964198557747,-0.6480464817522166,0.1954695077304166,1.8531384170199579,-0.015734964198557747,1.573819316272094,-0.24461259530598548,0.596562227640058,0.9321417422805507,-0.44523349939724377,-0.07650252744056436,0.6846286512595186,-0.44523349939724377,-0.4918385618163464,0.989958989232039,-0.8531472312752075,0.10523221520582753,0.13535733730271166,-0.8849107173056833,-0.5073997148873077,-0.1069583132087397,1.9085925209979264,1.4186970981267617,0.888674836109678,-0.6794490424983824,1.0043887198247081,0.6259595854721536,-0.07650252744056436,0.2852966167197613,-0.15273282774028654,0.0297158455536117,0.13535733730271166,-0.8690218779880967,0.8596469929949846,0.7139008185990915,-0.8849107173056833,0.888674836109678
3,392
Anion transmembrane transporter activity
14
47
2.66727
0.007647
P51797,P21796,P45880,Q9BQT8,P08195,Q14728,Q9H2D1,O43681,Q8TB61,Q9Y619,Q9H813,Q9UBX3,O43808,Q9C0H2
Functions
GO Molecular function
msigdb_gomf
228,69,102,393,71,475,15,523,508,87,381,26,219,95
2434,2333,523,219,2439,1623,1976,2571,71,2135,3378,997,1549,69,1551,2905,102,1679,228,1406,2648,2005,1256,1661,475,2386,562,1445,2890,3264,508,2352,1083,1244,1928,393,95,15,381,991,1104,2473,26,1342,1905,87,1567
-0.5073997148873077,-0.46075549648323305,0.8596469929949846,1.5175365324543044,-0.5073997148873077,-0.09172438937674851,-0.2753383056546045,-0.6010440292225467,2.5774251672985713,-0.3678171946564402,-3.3346573519697245,0.3300585863237035,-0.04609484197467206,2.6043294186857167,-0.04609484197467206,-0.8372867282398355,2.197563227073385,-0.12220433600304552,1.5034435722199273,0.0297158455536117,-0.6480464817522166,-0.2907199213981397,0.12030055776561276,-0.1069583132087397,0.9321417422805507,-0.47629050319229616,0.8160298348526115,0.014577395414097777,-0.8214403202477919,-1.352091936483502,0.888674836109678,-0.46075549648323305,0.2553993789324403,0.13535733730271166,-0.24461259530598548,1.0907625977334081,2.2930986183056987,3.760293155258865,1.1194765902923671,0.3449570020292946,0.24043388497129026,-0.522974005179062,3.476173526807814,0.07506070309973252,-0.22926842223566576,2.4018122550596814,-0.04609484197467206
3,392
Endoplasmic reticulum to golgi vesicle mediated transport
19
71
2.663897
0.007724
Q15363,Q6NUQ1,Q9Y282,O95070,O43731,P24390,Q9Y6B6,Q5JRA6,Q13190,O14653,Q15436,P49755,O15027,Q8NHH9,Q92734,Q96PC5,O14579,Q9Y3B3,Q9P2W9
Processes and pathways
GO Biological process
msigdb_gobp
386,519,14,269,149,28,158,423,165,289,435,565,194,321,467,243,252,124,125
1426,252,289,194,1568,971,1936,149,1856,1829,2060,1184,269,772,3322,815,1519,1433,28,1169,1325,565,3238,1888,2527,2379,2971,1461,1172,890,1682,1683,165,2720,386,435,423,2952,519,2147,1990,1667,321,1414,1531,467,700,1336,243,824,1121,1418,1900,1122,810,2636,1423,1793,125,1751,3253,591,14,2189,1585,1139,124,2400,3144,158,921
0.014577395414097777,1.4186970981267617,1.3194125750424903,1.6159385005727454,-0.06129269053099454,0.3449570020292946,-0.25996921007055324,1.8253608767518077,-0.21393665194747497,-0.19861724574074396,-0.32152087180770866,0.16543634416126807,1.362018084052379,0.5228837222779321,-1.6819559726880045,0.47854849943901234,-0.030908945292574343,0.014577395414097777,3.4241806746156223,0.18045863946931265,0.07506070309973252,0.8014705690921952,-1.2706332542898442,-0.22926842223566576,-0.5697761307887955,-0.47629050319229616,-0.8849107173056833,-0.00057286259791032,0.18045863946931265,0.4044403103634737,-0.12220433600304552,-0.12220433600304552,1.741824390244023,-0.6951707365076549,1.1051243960353279,1.018808669576008,1.0476193288474605,-0.8690218779880967,0.8741659228684505,-0.3678171946564402,-0.2753383056546045,-0.1069583132087397,1.2482182125944992,0.0297158455536117,-0.030908945292574343,0.9466108546188425,0.6112661660954188,0.07506070309973252,1.461110906640378,0.47854849943901234,0.22545709717825904,0.0297158455536117,-0.22926842223566576,0.22545709717825904,0.4933376536617622,-0.6323655241400963,0.0297158455536117,-0.1680153718164889,1.977722435244023,-0.15273282774028654,-1.319461443687167,0.7723215542957492,3.7859704508763934,-0.3832747697389823,-0.06129269053099454,0.21046898250401078,1.9915235827542386,-0.47629050319229616,-1.0606389558982219,1.8114594151764092,0.38958597328502204
3,392
Abnormal sternum morphology
34
123
2.662317
0.00776
Q15555,Q13510,P08236,Q7Z6Z7,Q99643,Q7LGA3,Q8NCH0,P31749,O95831,P04062,P55795,P34059,Q8NFV4,P30153,Q9BUK6,P78318,Q9UJX6,Q9UHX1,O75718,P21359,Q9H490,Q9NVI7,Q9Y619,Q2M1P5,Q9H9E3,P61978,O96028,P06753,Q08J23,Q9Y487,Q7RTS9,Q9Y4P3,Q9Y263,Q15056
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
504,132,514,651,530,400,22,23,30,32,36,180,440,564,57,446,324,67,454,204,597,339,87,354,356,349,226,610,361,235,507,512,644,253
2877,2854,3116,2436,1252,2334,2193,2367,1428,1460,2621,2964,692,454,1253,2194,30,226,844,32,610,854,1488,514,1144,1657,2923,204,1909,2504,2830,564,1438,23,2735,180,649,2310,1373,1059,1147,978,3197,1835,3292,2276,2648,1706,1256,36,1378,1573,349,3256,446,2445,2381,711,1862,2835,3220,861,2006,983,361,1633,132,1352,1917,1133,253,504,354,3263,790,2043,3268,1468,400,507,651,2094,22,1306,440,2776,1156,1640,2512,822,1848,842,2487,2655,3243,1692,3285,2073,2957,530,1581,2820,57,1476,1019,1643,597,356,2425,339,2900,67,2975,324,1456,644,2157,2001,235,2400,512,2302,87
-0.8214403202477919,-0.8056079589553966,-1.0445906823532496,-0.5073997148873077,0.12030055776561276,-0.46075549648323305,-0.3987451465185144,-0.47629050319229616,0.014577395414097777,-0.00057286259791032,-0.6323655241400963,-0.8849107173056833,0.6112661660954188,0.961070082526128,0.12030055776561276,-0.3987451465185144,3.37208282113663,1.5034435722199273,0.4489377993753778,3.2937373551059523,0.7285214102943242,0.4341161923697676,-0.015734964198557747,0.8741659228684505,0.1954695077304166,-0.1069583132087397,-0.8531472312752075,1.573819316272094,-0.24461259530598548,-0.5541621697421181,-0.7897895963070047,0.8014705690921952,0.014577395414097777,3.502130832268083,-0.710906100634738,1.671974639280965,0.6846286512595186,-0.44523349939724377,0.044842523349634685,0.2703536119434672,0.1954695077304166,0.3449570020292946,-1.141103441123685,-0.19861724574074396,-1.483251123536119,-0.4297244698805092,-0.6480464817522166,-0.13746249502499586,0.12030055776561276,3.2020295802887704,0.044842523349634685,-0.06129269053099454,1.1910943651123755,-1.3357688144594548,0.989958989232039,-0.5073997148873077,-0.47629050319229616,0.596562227640058,-0.21393665194747497,-0.7897895963070047,-1.2057460042171027,0.4341161923697676,-0.2907199213981397,0.3449570020292946,1.162475796263921,-0.09172438937674851,1.9085925209979264,0.0599574641453926,-0.24461259530598548,0.21046898250401078,1.4186970981267617,0.888674836109678,1.1910943651123755,-1.352091936483502,0.5081160512050436,-0.30611409685763147,-1.3684308687904816,-0.00057286259791032,1.0763911704719784,0.888674836109678,0.6846286512595186,-0.3369402862428846,3.553967705609741,0.09015227518848501,1.0043887198247081,-0.7424180239388641,0.1954695077304166,-0.09172438937674851,-0.5541621697421181,0.47854849943901234,-0.19861724574074396,0.4637485581792443,-0.5385614757094254,-0.6480464817522166,-1.2706332542898442,-0.12220433600304552,-1.4339458950700101,-0.32152087180770866,-0.8690218779880967,0.8596469929949846,-0.06129269053099454,-0.7739851845325647,2.725031627796951,-0.00057286259791032,0.31514907160504646,-0.09172438937674851,0.7577317502408601,1.1910943651123755,-0.4918385618163464,1.2196751063114128,-0.8214403202477919,2.644629964151358,-0.8849107173056833,1.2482182125944992,0.014577395414097777,0.6992699083324146,-0.3678171946564402,-0.2753383056546045,1.4893416625418183,-0.47629050319229616,0.888674836109678,-0.4297244698805092,2.4018122550596814
3,392
Primary adrenal insufficiency
6
15
2.660239
0.007809
O75381,Q9Y5Y5,P16435,P56589,P31749,P40855
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
280,130,516,464,23,93
2692,280,1055,516,23,93,1272,1835,464,588,1960,1262,1822,1969,130
-0.6794490424983824,1.3336236238545365,0.2703536119434672,0.8741659228684505,3.502130832268083,2.2930986183056987,0.10523221520582753,-0.19861724574074396,0.9466108546188425,0.7723215542957492,-0.25996921007055324,0.12030055776561276,-0.18331016512462858,-0.25996921007055324,1.936269398935176
3,392
Elevated pulmonary artery pressure
9
26
2.659414
0.007828
P04062,P20674,Q14108,P21359,O75844,P03886,Q8IZA0,Q9Y4U1,P00403
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,358,74,204,50,220,355,325,92
3196,50,795,92,1022,844,220,32,358,2923,204,472,2644,788,1406,1026,74,1578,790,1445,355,1640,1848,2615,2920,325
-1.141103441123685,2.8318251529978857,0.4933376536617622,2.2930986183056987,0.3002284258115414,0.4489377993753778,1.5175365324543044,3.2937373551059523,1.1767898212573111,-0.8531472312752075,1.573819316272094,0.9321417422805507,-0.6480464817522166,0.5081160512050436,0.0297158455536117,0.3002284258115414,2.5370126379799847,-0.06129269053099454,0.5081160512050436,0.014577395414097777,1.1910943651123755,-0.09172438937674851,-0.19861724574074396,-0.6166980548909288,-0.8372867282398355,1.2482182125944992
3,392
Nonalcoholic fatty liver disease
16
57
2.655944
0.007909
Q9P0J0,Q9Y6M9,O43676,P31751,P20674,O43674,O75306,P22695,Q99643,O14949,Q9UDW1,Q86Y39,P31749,Q96GC9,P14406,P00403
Processes and pathways
WikiPathways
msigdb_wp
522,394,38,101,358,389,417,106,530,18,82,466,23,186,282,92
2191,1318,2903,852,2520,18,389,38,3195,2855,2569,417,924,2161,973,2500,1544,795,92,1625,1185,2307,2196,876,282,3295,1656,2402,358,1909,106,3255,2309,23,101,1980,2857,537,2198,3275,837,1026,1442,2086,1443,1573,2142,2446,1277,2534,466,186,1692,530,522,82,394
-0.3987451465185144,0.07506070309973252,-0.8372867282398355,0.4341161923697676,-0.5697761307887955,3.6444348969265956,1.0907625977334081,3.149476125453242,-1.141103441123685,-0.8056079589553966,-0.6010440292225467,1.0476193288474605,0.37472066384711566,-0.3832747697389823,0.3449570020292946,-0.5541621697421181,-0.04609484197467206,0.4933376536617622,2.2930986183056987,-0.09172438937674851,0.16543634416126807,-0.44523349939724377,-0.3987451465185144,0.4192837063531287,1.3336236238545365,-1.4997187103625877,-0.1069583132087397,-0.4918385618163464,1.1767898212573111,-0.24461259530598548,2.1427969107941136,-1.3357688144594548,-0.44523349939724377,3.502130832268083,2.197563227073385,-0.2753383056546045,-0.8056079589553966,0.8451180196791206,-0.3987451465185144,-1.4011564023133367,0.4637485581792443,0.3002284258115414,0.014577395414097777,-0.3369402862428846,0.014577395414097777,-0.06129269053099454,-0.3678171946564402,-0.5073997148873077,0.10523221520582753,-0.5697761307887955,0.9466108546188425,1.6439740384202233,-0.12220433600304552,0.8596469929949846,0.8741659228684505,2.442452416251786,1.0907625977334081
3,392
Retinopathy
11
31
2.654923
0.007933
Q15555,P00846,Q5JRA6,O96028,P22413,O75306,P40763,P40939,P51648,Q9Y6B6,Q9NZ08
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
504,33,423,226,472,417,307,277,27,158,191
2877,2304,1879,417,1253,2194,226,33,1022,854,1548,1732,1943,472,307,277,835,2198,27,1889,539,1633,504,423,2957,3323,1615,2257,191,2156,158
-0.8214403202477919,-0.44523349939724377,-0.22926842223566576,1.0476193288474605,0.12030055776561276,-0.3987451465185144,1.5034435722199273,3.2806564295146425,0.3002284258115414,0.4341161923697676,-0.04609484197467206,-0.15273282774028654,-0.25996921007055324,0.9321417422805507,1.2767238749913556,1.3478254524900601,0.4637485581792443,-0.3987451465185144,3.4501901747304498,-0.22926842223566576,0.8451180196791206,-0.09172438937674851,0.888674836109678,1.0476193288474605,-0.8690218779880967,-1.6819559726880045,-0.07650252744056436,-0.4142283661153823,1.6299606471660821,-0.3678171946564402,1.8114594151764092
3,392
Copi mediated anterograde transport
19
60
2.654772
0.007936
Q15363,Q96MW5,Q13561,O43731,Q13813,P24390,Q9BUF5,Q13190,O14653,P49755,O75935,P84085,Q9UJW0,Q9H9E3,P04350,Q9Y3B3,Q14203,O14579,Q13885
Processes and pathways
Reactome Pathways
msigdb_reactome
386,403,650,149,663,28,426,165,289,565,197,586,86,356,482,124,491,252,503
252,289,2132,1568,971,2265,149,1856,197,772,482,1433,28,1169,2506,2480,1297,1325,565,3340,2527,2379,1707,801,1680,890,1326,696,1237,586,1381,1682,2530,1302,165,1662,650,663,503,491,3180,1044,386,2127,1717,1531,1785,1336,403,1035,426,1418,1900,356,1751,86,968,124,3144,1799
1.4186970981267617,1.3194125750424903,-0.3678171946564402,-0.06129269053099454,0.3449570020292946,-0.4297244698805092,1.8253608767518077,-0.21393665194747497,1.6019075774365181,0.5228837222779321,0.9176627193149094,0.014577395414097777,3.4241806746156223,0.18045863946931265,-0.5541621697421181,-0.5385614757094254,0.09015227518848501,0.07506070309973252,0.8014705690921952,-1.8662601339900915,-0.5697761307887955,-0.47629050319229616,-0.13746249502499586,0.4933376536617622,-0.12220433600304552,0.4044403103634737,0.07506070309973252,0.6112661660954188,0.13535733730271166,0.7723215542957492,0.044842523349634685,-0.12220433600304552,-0.5697761307887955,0.09015227518848501,1.741824390244023,-0.1069583132087397,0.6846286512595186,0.6699770190108111,0.888674836109678,0.9031737594044319,-1.1088728099650214,0.2852966167197613,1.1051243960353279,-0.3523723803792923,-0.13746249502499586,-0.030908945292574343,-0.1680153718164889,0.07506070309973252,1.0763911704719784,0.3002284258115414,1.0476193288474605,0.0297158455536117,-0.22926842223566576,1.1910943651123755,-0.15273282774028654,2.4153666489525016,0.3598443506231174,1.9915235827542386,-1.0606389558982219,-0.1680153718164889
3,392
Intrinsic pathway for apoptosis
8
23
2.653987
0.007955
P31946,P31751,Q9NR28,Q07021,P40763,P31749,Q04917,P62258
Processes and pathways
Reactome Pathways
msigdb_reactome
535,101,209,378,307,23,474,283
1939,1321,1322,2063,1371,23,101,535,307,2857,835,1443,1131,283,634,1326,2201,474,378,2446,1504,1785,209
-0.25996921007055324,0.07506070309973252,0.07506070309973252,-0.32152087180770866,0.044842523349634685,3.502130832268083,2.197563227073385,0.8451180196791206,1.2767238749913556,-0.8056079589553966,0.4637485581792443,0.014577395414097777,0.21046898250401078,1.3336236238545365,0.6992699083324146,0.07506070309973252,-0.3987451465185144,0.9321417422805507,1.1194765902923671,-0.5073997148873077,-0.015734964198557747,-0.1680153718164889,1.5597619353863794
3,392
Stabilization of p53
7
41
2.648266
0.008091
Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323
Processes and pathways
Reactome Pathways
msigdb_reactome
64,193,164,227,75,116,121
193,3012,1878,872,1621,1396,1701,2268,1939,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,835,759,2169,445,75,1211,1299,1096,116,889,2141,1836,121,2007,2888,1353,2794,825,1962,64,1390
1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,-0.4297244698805092,-0.25996921007055324,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.4637485581792443,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685
3,392
Class i peroxisomal membrane protein import
7
11
2.64793
0.008099
O75381,Q9Y5Y5,P51648,Q9NR77,Q9Y3D6,O43808,P40855
Processes and pathways
Reactome Pathways
msigdb_reactome
280,130,27,108,469,219,93
219,280,2233,93,27,464,636,1783,108,469,130
1.5175365324543044,1.3336236238545365,-0.4142283661153823,2.2930986183056987,3.4501901747304498,0.9466108546188425,0.6992699083324146,-0.1680153718164889,2.1153656498312228,0.9466108546188425,1.936269398935176
3,392
Asymmetric localization of pcp proteins
7
39
2.647758
0.008103
Q9UL46,O00231,P28072,P28070,P49721,P61289,Q06323
Processes and pathways
Reactome Pathways
msigdb_reactome
64,193,164,227,75,116,121
193,3012,1878,872,1621,1396,1701,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,1299,1096,116,889,2141,1836,121,2007,2984,2888,1353,2794,825,1962,64,1390
1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.900813798450678,-0.8214403202477919,0.0599574641453926,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,2.671459958677549,0.044842523349634685
3,392
The role of gtse1 in g2 m progression after g2 checkpoint
19
50
2.642658
0.008226
Q9BUF5,P53350,P28072,P06493,Q99436,P68371,P49720,Q9UL46,O00231,P49721,Q15691,P28070,P04350,P20618,O00487,P61289,Q06323,Q13885,P43686
Processes and pathways
Reactome Pathways
msigdb_reactome
426,671,164,796,825,696,445,64,193,75,848,227,482,236,872,116,121,503,759
193,3012,1878,872,1621,1396,1701,1347,482,1939,796,1626,1858,1942,1230,236,929,1231,1832,1659,2168,227,164,1145,1805,759,2169,445,75,1211,671,1299,1096,116,889,2141,1836,696,121,2007,503,2888,1353,848,2794,825,1962,426,64,1390
1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.0599574641453926,0.9176627193149094,-0.25996921007055324,0.4933376536617622,-0.09172438937674851,-0.21393665194747497,-0.25996921007055324,0.13535733730271166,1.4752307813901213,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.1504025880743201,0.655314983080957,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,0.6112661660954188,2.0191011953082207,-0.2907199213981397,0.888674836109678,-0.8214403202477919,0.0599574641453926,0.4489377993753778,-0.7581946761452075,0.47854849943901234,-0.25996921007055324,1.0476193288474605,2.671459958677549,0.044842523349634685
3,392
Outer membrane
22
96
2.641438
0.008255
O00264,Q9BWH2,O43169,P09601,Q9BUR5,Q13505,Q8WY22,Q9HCL2,Q9NS69,P52789,Q8NAN2,Q9BUK6,Q9NZ45,P21796,Q5XKP0,Q9Y3D6,Q9Y6C9,Q15388,Q6NUM9,P45880,Q9Y512,Q8N4H5
Localization
GO Cellular component
msigdb_gocc
0,137,388,10,531,31,40,298,42,420,437,57,61,69,200,469,213,342,476,102,365,245
0,1828,388,707,2106,996,692,1702,2336,2523,1624,3104,2881,2027,10,2748,69,775,1571,2671,2002,2672,102,978,1093,420,2887,761,1301,2446,1029,934,31,1504,2533,342,1076,1214,1813,2988,200,476,2606,2350,1840,1842,804,1358,1557,2249,2467,2126,245,2563,437,1783,699,1156,40,1690,937,2654,1067,1961,713,1245,1788,1034,57,531,3069,137,554,2726,298,1790,1538,1388,42,2360,2515,1389,2899,3194,868,2566,61,631,2823,2784,2824,1905,1265,469,365,213
4.357302273053826,-0.19861724574074396,1.0907625977334081,0.596562227640058,-0.3523723803792923,0.3300585863237035,0.6112661660954188,-0.13746249502499586,-0.46075549648323305,-0.5697761307887955,-0.09172438937674851,-1.0285571596923793,-0.8214403202477919,-0.30611409685763147,3.9012117159107698,-0.726655180985889,2.6043294186857167,0.5228837222779321,-0.06129269053099454,-0.6637409727699075,-0.2907199213981397,-0.6637409727699075,2.197563227073385,0.3449570020292946,0.24043388497129026,1.0476193288474605,-0.8214403202477919,0.5376406969420575,0.09015227518848501,-0.5073997148873077,0.3002284258115414,0.37472066384711566,3.359041854851364,-0.015734964198557747,-0.5697761307887955,1.205389452082045,0.2553993789324403,0.1504025880743201,-0.18331016512462858,-0.900813798450678,1.5878678564641069,0.9321417422805507,-0.6166980548909288,-0.46075549648323305,-0.19861724574074396,-0.19861724574074396,0.4933376536617622,0.0599574641453926,-0.04609484197467206,-0.4142283661153823,-0.522974005179062,-0.3523723803792923,1.4469820160729245,-0.5854034026110678,1.018808669576008,-0.1680153718164889,0.6112661660954188,0.1954695077304166,3.0836302701028453,-0.12220433600304552,0.37472066384711566,-0.6480464817522166,0.2703536119434672,-0.25996921007055324,0.596562227640058,0.13535733730271166,-0.1680153718164889,0.3002284258115414,2.725031627796951,0.8596469929949846,-0.9805445753920402,1.8947415678252209,0.8305789759854734,-0.6951707365076549,1.3051922828493479,-0.1680153718164889,-0.030908945292574343,0.044842523349634685,3.0704404222415245,-0.46075549648323305,-0.5541621697421181,0.044842523349634685,-0.8214403202477919,-1.1249806168260381,0.4341161923697676,-0.5854034026110678,2.6982604715752156,0.7139008185990915,-0.7739851845325647,-0.7424180239388641,-0.7739851845325647,-0.22926842223566576,0.12030055776561276,0.9466108546188425,1.162475796263921,1.5456956922416358
3,392
Episodic vomiting
6
11
2.638804
0.00832
P00846,P61978,P22695,Q9Y619,P03886,P00403
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,349,106,87,220,92
92,33,220,106,2624,377,818,349,1314,2424,87
2.2930986183056987,3.2806564295146425,1.5175365324543044,2.1427969107941136,-0.6323655241400963,1.1194765902923671,0.47854849943901234,1.1910943651123755,0.09015227518848501,-0.4918385618163464,2.4018122550596814
3,392
Endomembrane system organization
54
184
2.636784
0.00837
Q9BRG1,A0MZ66,P63104,Q5SQN1,Q15363,Q7Z6Z7,Q8N4V1,O95197,Q9P253,Q15006,O43681,Q96MW5,Q92783,P31749,P53350,Q5JRA6,Q9BTU6,Q13190,Q9UL15,O43765,Q8TBA6,O14657,O75844,P49755,Q13277,Q15629,Q8N3R9,Q96GC9,Q9UH99,O15027,O15260,Q9Y3E7,Q8NHH9,P46379,Q8N1F7,Q14108,Q9UN37,Q9ULX6,O95721,Q9P0I2,Q9H9E3,Q86XL3,P31751,O43752,Q6NUK4,Q5T0N5,Q8N5M9,Q9UNF0,Q14203,Q16739,Q7RTS9,Q15041,Q9Y3B3,Q9P2W9
Processes and pathways
GO Biological process
msigdb_gobp
128,384,634,259,386,651,529,141,142,143,523,403,667,23,671,423,553,165,428,545,172,305,50,565,566,59,576,186,448,194,65,716,321,319,331,74,725,724,593,345,356,100,101,225,362,492,368,370,491,112,507,248,124,125
1541,384,2962,1828,2826,1485,305,1345,831,969,194,1367,1568,65,1936,756,523,225,545,1757,1856,2368,2060,3196,2976,50,1319,3032,1184,141,3322,593,844,796,1432,1116,2165,1057,1944,1322,2063,23,101,1372,1373,2548,858,2905,1374,319,2506,1298,565,978,1272,878,1768,1679,671,1171,1095,1573,1172,1060,2344,2834,890,634,1948,1237,2038,1381,1862,2604,1682,1600,1864,1683,1302,717,1213,165,566,74,491,1044,143,248,1134,2091,2533,386,59,112,1780,2283,423,2208,259,492,2952,912,362,3276,3379,507,2147,1716,651,1990,1469,1135,100,1384,936,331,2212,576,529,368,2415,1385,1306,2469,321,2045,172,1334,1308,1531,2564,667,822,186,1416,1336,403,2710,1963,128,2819,1121,553,1581,1418,2219,2051,1263,1643,3338,2292,1159,356,2052,1363,1288,1851,2427,2566,1291,345,1793,142,125,448,2131,2299,428,2519,724,725,370,884,2938,3162,1585,2399,968,1265,1139,124,716,1086,921
-0.04609484197467206,1.1051243960353279,-0.8849107173056833,-0.19861724574074396,-0.7897895963070047,-0.015734964198557747,1.2767238749913556,0.0599574641453926,0.4637485581792443,0.3449570020292946,1.6159385005727454,0.044842523349634685,-0.06129269053099454,2.644629964151358,-0.25996921007055324,0.5376406969420575,0.8596469929949846,1.5034435722199273,0.8305789759854734,-0.1680153718164889,-0.21393665194747497,-0.47629050319229616,-0.32152087180770866,-1.141103441123685,-0.900813798450678,2.8318251529978857,0.07506070309973252,-0.9486089895638056,0.16543634416126807,1.8808822458505576,-1.6819559726880045,0.7577317502408601,0.4489377993753778,0.4933376536617622,0.014577395414097777,0.22545709717825904,-0.3832747697389823,0.2703536119434672,-0.25996921007055324,0.07506070309973252,-0.32152087180770866,3.502130832268083,2.197563227073385,0.044842523349634685,0.044842523349634685,-0.5854034026110678,0.4341161923697676,-0.8372867282398355,0.044842523349634685,1.2482182125944992,-0.5541621697421181,0.09015227518848501,0.8014705690921952,0.3449570020292946,0.10523221520582753,0.4192837063531287,-0.1680153718164889,-0.12220433600304552,0.655314983080957,0.18045863946931265,0.24043388497129026,-0.06129269053099454,0.18045863946931265,0.2703536119434672,-0.46075549648323305,-0.7897895963070047,0.4044403103634737,0.6992699083324146,-0.25996921007055324,0.13535733730271166,-0.30611409685763147,0.044842523349634685,-0.21393665194747497,-0.6166980548909288,-0.12220433600304552,-0.07650252744056436,-0.21393665194747497,-0.12220433600304552,0.09015227518848501,0.5818477409079303,0.1504025880743201,1.741824390244023,0.8014705690921952,2.5370126379799847,0.9031737594044319,0.2852966167197613,1.8670145354751024,1.4328440873723212,0.21046898250401078,-0.3369402862428846,-0.5697761307887955,1.1051243960353279,2.6982604715752156,2.074158219188792,-0.1680153718164889,-0.4297244698805092,1.0476193288474605,-0.3987451465185144,1.3903758478681065,0.9031737594044319,-0.8690218779880967,0.38958597328502204,1.162475796263921,-1.4011564023133367,-3.4094648282561173,0.888674836109678,-0.3678171946564402,-0.13746249502499586,0.6846286512595186,-0.2753383056546045,-0.00057286259791032,0.21046898250401078,2.224898571271148,0.044842523349634685,0.37472066384711566,1.233951351838413,-0.3987451465185144,0.7869011513881382,0.8596469929949846,1.1481522657707446,-0.4918385618163464,0.044842523349634685,0.09015227518848501,-0.522974005179062,1.2482182125944992,-0.30611409685763147,1.71391040052824,0.07506070309973252,0.09015227518848501,-0.030908945292574343,-0.5854034026110678,0.6699770190108111,0.47854849943901234,1.6439740384202233,0.0297158455536117,0.07506070309973252,1.0763911704719784,-0.6794490424983824,-0.25996921007055324,1.936269398935176,-0.7739851845325647,0.22545709717825904,0.8305789759854734,-0.06129269053099454,0.0297158455536117,-0.3987451465185144,-0.30611409685763147,0.12030055776561276,-0.09172438937674851,-1.8325924202791186,-0.4297244698805092,0.1954695077304166,1.1910943651123755,-0.30611409685763147,0.0599574641453926,0.10523221520582753,-0.19861724574074396,-0.4918385618163464,-0.5854034026110678,0.10523221520582753,1.205389452082045,-0.1680153718164889,1.8808822458505576,1.977722435244023,0.989958989232039,-0.3523723803792923,-0.4297244698805092,1.0476193288474605,-0.5541621697421181,0.5818477409079303,0.5818477409079303,1.1481522657707446,0.4192837063531287,-0.8531472312752075,-1.0767020329756654,-0.06129269053099454,-0.47629050319229616,0.3598443506231174,0.12030055776561276,0.21046898250401078,1.9915235827542386,0.596562227640058,0.2553993789324403,0.38958597328502204
3,392
Polyneuropathy
10
20
2.625054
0.008664
P00846,P04066,Q9NZJ7,P21359,P35670,P07602,O95721,Q15041,P03886,O95831
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,418,631,204,430,117,593,248,220,30
707,593,30,33,220,418,117,1230,204,1980,430,1981,1381,248,1354,3043,2450,2473,631,2493
0.596562227640058,0.7577317502408601,3.37208282113663,3.2806564295146425,1.5175365324543044,1.0476193288474605,2.0328776982252563,0.13535733730271166,1.573819316272094,-0.2753383056546045,1.0332188640882995,-0.2753383056546045,0.044842523349634685,1.4328440873723212,0.0599574641453926,-0.9486089895638056,-0.5073997148873077,-0.522974005179062,0.7139008185990915,-0.5385614757094254
3,392
Porphyrin containing compound metabolic process
6
17
2.623012
0.008716
O00264,O75027,P09601,Q7KZN9,P30519,P36551
Processes and pathways
GO Biological process
msigdb_gobp
0,39,10,329,20,377
0,39,2109,1209,10,483,20,775,377,2884,679,1986,329,2741,1873,2296,811
4.357302273053826,3.136320692524441,-0.3523723803792923,0.1504025880743201,3.9012117159107698,0.9176627193149094,3.5669108013937043,0.5228837222779321,1.1194765902923671,-0.8214403202477919,0.6259595854721536,-0.2753383056546045,1.233951351838413,-0.710906100634738,-0.21393665194747497,-0.4297244698805092,0.4933376536617622
3,392
Abnormal enchondral ossification
14
34
2.617419
0.00886
O75381,Q9UG56,Q9Y5Y5,O96028,Q2M1P5,Q96HY6,P10644,P56589,Q9Y619,Q7RTS9,P38435,Q8WVQ1,P40855,P22413
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
280,192,130,226,354,432,397,464,87,507,444,322,93,472
2057,2193,2964,280,1253,226,514,397,2923,472,2311,444,93,1272,464,1130,1633,1133,2679,2722,2753,354,507,1306,322,2655,432,2957,1072,2784,192,2939,130,87
-0.32152087180770866,-0.3987451465185144,-0.8849107173056833,1.3336236238545365,0.12030055776561276,1.5034435722199273,0.8741659228684505,1.0763911704719784,-0.8531472312752075,0.9321417422805507,-0.44523349939724377,0.989958989232039,2.2930986183056987,0.10523221520582753,0.9466108546188425,0.21046898250401078,-0.09172438937674851,0.21046898250401078,-0.6637409727699075,-0.6951707365076549,-0.726655180985889,1.1910943651123755,0.888674836109678,0.09015227518848501,1.2482182125944992,-0.6480464817522166,1.0332188640882995,-0.8690218779880967,0.2703536119434672,-0.7424180239388641,1.6299606471660821,-0.8531472312752075,1.936269398935176,2.4018122550596814
3,392
Ion transport
17
64
2.61702
0.00887
P00846,P51797,Q9H813,P21796,P45880,O75964,Q9Y487,Q8TAD4,P35670,Q93050,Q9NWR8,Q8NEW0,P24539,P06576,Q9H4I9,Q9C0H2,P36543
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
33,228,381,69,102,73,235,110,430,175,207,109,463,214,380,95,473
2434,784,73,1518,1253,1624,33,1976,1730,2229,214,2135,1116,1658,950,3347,69,1118,463,2644,1979,430,1860,473,2236,102,3035,1679,228,1406,2979,1256,2237,1982,526,2579,861,2869,863,3264,1360,1687,109,110,2352,1472,175,749,1244,2289,3069,95,1748,702,380,381,2427,207,2398,2329,1905,235,617,1567
-0.5073997148873077,0.5081160512050436,2.563961827278685,-0.030908945292574343,0.12030055776561276,-0.09172438937674851,3.2806564295146425,-0.2753383056546045,-0.15273282774028654,-0.4142283661153823,1.5316205651807586,-0.3678171946564402,0.22545709717825904,-0.1069583132087397,0.3598443506231174,-2.018657093338504,2.6043294186857167,0.22545709717825904,0.9466108546188425,-0.6480464817522166,-0.2753383056546045,1.0332188640882995,-0.21393665194747497,0.9321417422805507,-0.4142283661153823,2.197563227073385,-0.9486089895638056,-0.12220433600304552,1.5034435722199273,0.0297158455536117,-0.900813798450678,0.12030055776561276,-0.4142283661153823,-0.2753383056546045,0.8596469929949846,-0.6010440292225467,0.4341161923697676,-0.8056079589553966,0.4341161923697676,-1.352091936483502,0.0599574641453926,-0.12220433600304552,2.1016379298886707,2.1016379298886707,-0.46075549648323305,-0.00057286259791032,1.6999404710130017,0.5523870051126312,0.13535733730271166,-0.4297244698805092,-0.9805445753920402,2.2930986183056987,-0.15273282774028654,0.6112661660954188,1.1194765902923671,1.1194765902923671,-0.4918385618163464,1.573819316272094,-0.47629050319229616,-0.44523349939724377,-0.22926842223566576,1.4893416625418183,0.7285214102943242,-0.04609484197467206
3,392
Primary mitochondrial disease
29
107
2.614262
0.008942
Q9P0J0,Q9Y6M9,Q9BQT8,Q96CU9,Q6DKK2,O14949,Q9UBX3,O95831,P00846,O43676,O75306,Q70HW3,Q7LG56,P49411,Q6P4A7,Q5XKP0,Q7KZN9,Q86Y39,O75880,P03886,P00403,P20674,P22695,Q5JPH6,Q9BQP7,O75208,Q8IUX1,Q5JTZ9,Q07021
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
522,394,393,402,144,18,26,30,33,38,417,44,174,433,196,200,329,466,462,220,92,358,106,237,496,239,250,505,378
2191,2903,18,38,3195,2692,2304,707,239,2569,417,924,1055,462,1544,30,92,33,220,3148,1185,2134,997,876,3295,2402,358,106,2644,3255,1979,2309,2672,2377,537,433,3275,2861,2978,1808,953,980,1893,2280,378,621,2534,1813,2627,237,505,2510,1578,1986,200,144,196,44,329,1816,174,466,250,778,1100,640,1386,2815,895,402,3243,1219,1005,2610,1284,3323,1050,2611,496,393,1036,1615,1582,1671,1262,809,2588,2185,643,3314,2763,944,522,2296,26,2742,2920,1826,2190,1969,1248,1651,3185,1224,1206,1674,394
-0.3987451465185144,-0.8372867282398355,3.6444348969265956,3.149476125453242,-1.141103441123685,-0.6794490424983824,-0.44523349939724377,0.596562227640058,1.461110906640378,-0.6010440292225467,1.0476193288474605,0.37472066384711566,0.2703536119434672,0.9466108546188425,-0.04609484197467206,3.37208282113663,2.2930986183056987,3.2806564295146425,1.5175365324543044,-1.0767020329756654,0.16543634416126807,-0.3678171946564402,0.3300585863237035,0.4192837063531287,-1.4997187103625877,-0.4918385618163464,1.1767898212573111,2.1427969107941136,-0.6480464817522166,-1.3357688144594548,-0.2753383056546045,-0.44523349939724377,-0.6637409727699075,-0.47629050319229616,0.8451180196791206,1.018808669576008,-1.4011564023133367,-0.8056079589553966,-0.900813798450678,-0.18331016512462858,0.3598443506231174,0.3449570020292946,-0.22926842223566576,-0.4297244698805092,1.1194765902923671,0.7139008185990915,-0.5697761307887955,-0.18331016512462858,-0.6323655241400963,1.4752307813901213,0.888674836109678,-0.5541621697421181,-0.06129269053099454,-0.2753383056546045,1.5878678564641069,1.8670145354751024,1.6159385005727454,3.0043870268143222,1.233951351838413,-0.18331016512462858,1.6999404710130017,0.9466108546188425,1.4328440873723212,0.5228837222779321,0.24043388497129026,0.6992699083324146,0.044842523349634685,-0.7739851845325647,0.4044403103634737,1.0763911704719784,-1.2706332542898442,0.1504025880743201,0.3300585863237035,-0.6166980548909288,0.10523221520582753,-1.6819559726880045,0.2852966167197613,-0.6166980548909288,0.9031737594044319,1.0907625977334081,0.3002284258115414,-0.07650252744056436,-0.06129269053099454,-0.1069583132087397,0.12030055776561276,0.4933376536617622,-0.6010440292225467,-0.3832747697389823,0.6992699083324146,-1.6154534426268758,-0.726655180985889,0.37472066384711566,0.8741659228684505,-0.4297244698805092,3.476173526807814,-0.710906100634738,-0.8372867282398355,-0.18331016512462858,-0.3832747697389823,-0.25996921007055324,0.13535733730271166,-0.09172438937674851,-1.1088728099650214,0.1504025880743201,0.16543634416126807,-0.1069583132087397,1.0907625977334081
3,392
Positive regulation of peptidase activity
15
44
2.603657
0.009224
Q9UL46,Q9P0J0,Q06323,P05067,O43464,Q96HY6,Q9Y3D6,Q9NR28,P40763,Q9Y255,P61289,P23396,O14737,Q96A26,O95831
Processes and pathways
GO Biological process
msigdb_gobp
64,522,121,513,203,432,469,209,307,598,116,217,341,58,30
872,1266,341,203,783,1829,1430,1729,30,513,1114,2028,217,307,1350,2198,3238,1461,116,2140,2927,1326,2577,2382,1097,121,2446,2173,1329,1504,2888,1985,2418,2178,58,432,684,209,631,522,3307,64,598,469
0.4192837063531287,0.10523221520582753,1.205389452082045,1.573819316272094,0.5081160512050436,-0.19861724574074396,0.014577395414097777,-0.15273282774028654,3.37208282113663,0.8741659228684505,0.22545709717825904,-0.30611409685763147,1.5316205651807586,1.2767238749913556,0.0599574641453926,-0.3987451465185144,-1.2706332542898442,-0.00057286259791032,2.046646024024901,-0.3678171946564402,-0.8531472312752075,0.07506070309973252,-0.6010440292225467,-0.47629050319229616,0.24043388497129026,2.0191011953082207,-0.5073997148873077,-0.3832747697389823,0.07506070309973252,-0.015734964198557747,-0.8214403202477919,-0.2753383056546045,-0.4918385618163464,-0.3832747697389823,2.711649711497065,1.0332188640882995,0.6259595854721536,1.5597619353863794,0.7139008185990915,0.8741659228684505,-1.5657532843548536,2.671459958677549,0.7577317502408601,0.9466108546188425
3,392
Abnormality of head blood vessel
15
29
2.600243
0.009316
P00846,P10619,Q13510,Q9NZJ7,P21359,P35250,P04114,P17900,P07602,Q9Y4P3,Q8NFV4,P06865,P03886,Q15056,P22413
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,35,132,631,204,649,647,146,117,512,440,215,220,253,472
1182,2456,873,1252,33,220,647,215,117,2269,35,2642,1144,146,204,709,472,649,3289,2971,2445,132,253,440,1745,2957,631,2975,512
0.16543634416126807,-0.522974005179062,0.4192837063531287,0.12030055776561276,3.2806564295146425,1.5175365324543044,0.6846286512595186,1.5316205651807586,2.0328776982252563,-0.4297244698805092,3.2151509431473015,-0.6480464817522166,0.1954695077304166,1.8531384170199579,1.573819316272094,0.596562227640058,0.9321417422805507,0.6846286512595186,-1.4667998334603056,-0.8849107173056833,-0.5073997148873077,1.9085925209979264,1.4186970981267617,1.0043887198247081,-0.15273282774028654,-0.8690218779880967,0.7139008185990915,-0.8849107173056833,0.888674836109678
3,392
Microtubule associated complex
16
56
2.592798
0.00952
A0MZ66,Q9Y496,O94927,O75935,P33176,Q9NSK0,O60333,Q14203,P42025,Q68CZ6,Q9H6D7,Q9UJW0,Q96CS2,Q9NVX0,Q2M1P5,O60282
Localization
GO Cellular component
msigdb_gocc
384,129,318,197,455,72,169,491,179,465,21,86,373,316,354,408
384,2364,1087,2265,408,169,197,318,3103,1654,904,3092,976,455,179,1374,2601,2550,1889,801,1326,661,2121,1662,650,491,3180,2679,504,354,2388,1898,465,1357,2511,766,1306,2708,2776,373,2655,1785,1670,1693,3098,1285,2074,1419,21,3159,72,316,86,1344,129,1799
1.1051243960353279,-0.47629050319229616,0.24043388497129026,-0.4297244698805092,1.062010089223635,1.71391040052824,1.6019075774365181,1.2482182125944992,-1.0285571596923793,-0.1069583132087397,0.38958597328502204,-1.0125383355924664,0.3449570020292946,0.961070082526128,1.6859618908518097,0.044842523349634685,-0.6166980548909288,-0.5854034026110678,-0.22926842223566576,0.4933376536617622,0.07506070309973252,0.6699770190108111,-0.3523723803792923,-0.1069583132087397,0.6846286512595186,0.9031737594044319,-1.1088728099650214,-0.6637409727699075,0.888674836109678,1.1910943651123755,-0.47629050319229616,-0.22926842223566576,0.9466108546188425,0.0599574641453926,-0.5541621697421181,0.5376406969420575,0.09015227518848501,-0.6794490424983824,-0.7424180239388641,1.1338192053070948,-0.6480464817522166,-0.1680153718164889,-0.1069583132087397,-0.12220433600304552,-1.0125383355924664,0.10523221520582753,-0.32152087180770866,0.0297158455536117,3.5669108013937043,-1.0767020329756654,2.5774251672985713,1.262475712405316,2.4153666489525016,0.07506070309973252,1.936269398935176,-0.1680153718164889
3,392
Switching of origins to a post replicative state
15
58
2.592094
0.009539
Q9UL46,O00231,P28072,Q9UJX6,P28070,P24941,P49721,P20618,Q14566,P61289,Q9UJX5,Q9Y619,Q06323,P49720,Q9UJX4
Processes and pathways
Reactome Pathways
msigdb_reactome
64,193,164,324,227,547,75,236,371,116,569,87,121,445,544
193,3012,1878,872,1621,1396,1701,1230,236,547,2525,929,1231,1832,1659,2168,227,164,1145,2717,977,2032,905,1805,759,2169,445,75,1011,1211,1299,1096,116,889,2141,1836,1837,121,2007,1684,371,2888,1353,1151,2794,914,825,1962,1038,3218,2431,609,544,569,324,64,1390,87
1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.4192837063531287,-0.09172438937674851,0.0297158455536117,-0.13746249502499586,0.13535733730271166,1.4752307813901213,0.8305789759854734,-0.5697761307887955,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.6951707365076549,0.3449570020292946,-0.30611409685763147,0.38958597328502204,-0.18331016512462858,0.5376406969420575,-0.3832747697389823,0.989958989232039,2.5100333281525296,0.31514907160504646,0.1504025880743201,0.09015227518848501,0.24043388497129026,2.046646024024901,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.19861724574074396,2.0191011953082207,-0.2907199213981397,-0.12220433600304552,1.1338192053070948,-0.8214403202477919,0.0599574641453926,0.1954695077304166,-0.7581946761452075,0.38958597328502204,0.47854849943901234,-0.25996921007055324,0.3002284258115414,-1.1895625635407403,-0.4918385618163464,0.7431317115189636,0.8451180196791206,0.8014705690921952,1.2482182125944992,2.671459958677549,0.044842523349634685,2.4018122550596814
3,392
Mitochondrial envelope
93
334
2.586059
0.009708
O00264,Q9P0J0,Q69YU5,Q99595,O60830,P09601,Q9H061,Q9BUR5,Q9H2D1,Q99643,O14949,P47985,Q9UBX3,Q9UDX5,O95831,Q13505,P00846,O43676,O75027,Q8WY22,Q9BX68,Q9NS69,Q70HW3,Q6KCM7,Q16540,Q9BUK6,Q96A26,Q9NZ45,Q9BRJ2,O43615,P21796,Q8WUK0,O75964,Q13423,Q15070,Q9UDW1,Q10713,Q9Y619,P82933,P00403,Q567V2,P45880,P22695,Q9BSK2,Q9BWH2,Q6DKK2,Q9UG56,Q13084,Q6P4A7,Q5XKP0,O43464,P23786,Q9NWR8,Q9NR28,Q9Y6C9,P23396,P06576,P03886,P82664,O75208,Q8N4H5,Q8IUX1,Q9Y5J9,P40939,P14406,Q8N8Q8,Q9HCL2,Q9H3K2,Q7KZN9,O00584,Q9NVI7,Q15388,O14925,P20674,Q9Y512,Q9H4I9,P36551,Q9Y6M9,Q9BQT8,O43169,O43674,Q96CU9,P53701,P52789,O75306,Q8NAN2,Q9Y3D6,P24539,Q86Y39,O75880,Q8IYU8,P22830,Q8N442
Localization
GO Cellular component
msigdb_gocc
0,522,5,6,9,10,12,531,15,530,18,537,26,29,30,31,33,38,39,40,554,42,44,562,567,57,58,61,578,66,69,589,73,588,81,82,83,87,91,92,96,102,106,114,137,144,192,195,196,200,203,205,207,209,213,217,214,220,221,239,245,250,268,277,282,291,298,310,329,326,339,342,346,358,365,380,377,394,393,388,389,402,411,420,417,437,469,463,466,462,485,483,494
2191,0,1828,2903,326,852,2520,346,18,1367,1727,2713,388,203,66,389,38,3195,2663,2304,2855,707,2106,9,39,239,2569,417,996,692,1857,924,1700,1591,2439,462,784,73,1729,1702,2161,2336,973,2500,1253,1544,1623,2523,30,795,1624,3104,92,33,220,2571,214,3147,1185,2134,2027,10,2307,2543,2196,2028,3326,997,1549,3272,876,282,3295,1656,1402,1883,2748,2402,358,69,1909,2114,106,483,217,205,463,2644,3255,1979,2376,2458,775,2309,1980,1571,648,1189,2065,1860,377,2671,277,2002,2673,102,537,3035,2751,818,3275,2884,1093,2860,1026,420,2978,1000,2648,411,2528,1706,979,2887,2237,1982,761,980,2482,221,2508,1892,2406,1893,91,1681,1630,2702,1661,2446,1029,83,1865,717,934,195,3286,588,31,1504,820,2069,81,2533,342,1076,1466,567,1277,2534,1214,2244,1813,96,984,2988,200,5,144,2389,562,1445,2973,196,1467,2606,2558,2350,2559,44,329,2560,1840,1046,1842,804,466,250,1358,1557,2249,485,2467,778,2126,494,245,2563,291,2451,437,1047,1783,1687,640,2815,589,1719,699,40,2631,642,1690,937,58,2392,749,842,1282,988,402,2654,2216,1612,2609,1067,1219,1005,1083,1961,806,713,2762,1245,6,1788,530,2289,1069,393,578,1036,114,1084,1615,1582,57,531,3391,137,554,3142,1537,2781,1929,2050,965,2633,12,1201,15,3293,1052,310,380,2588,991,2726,1104,2185,1202,2936,2473,298,1454,2424,1850,643,883,1790,1538,1388,209,2741,2098,42,2360,2515,1389,339,1998,2899,207,1422,2960,3194,868,2258,61,631,3200,944,522,1873,2823,26,82,29,192,2824,1342,1999,2851,598,1826,1905,2330,2190,1969,2261,1265,3185,1755,1224,469,1206,739,365,3101,268,87,213,394,1108
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3,392
Mammary gland development
6
24
2.584996
0.009738
P31751,P52789,Q9UNS2,P31749,P00403,Q13505
Processes and pathways
GO Biological process
msigdb_gobp
101,420,406,23,92,31
92,1431,1320,1704,845,2944,2063,23,101,430,2198,420,954,861,2446,31,2984,2040,1788,1928,1288,2054,406,1697
2.2930986183056987,0.014577395414097777,0.07506070309973252,-0.13746249502499586,0.4489377993753778,-0.8690218779880967,-0.32152087180770866,3.502130832268083,2.197563227073385,1.0332188640882995,-0.3987451465185144,1.0476193288474605,0.3598443506231174,0.4341161923697676,-0.5073997148873077,3.359041854851364,-0.900813798450678,-0.30611409685763147,-0.1680153718164889,-0.24461259530598548,0.10523221520582753,-0.30611409685763147,1.0763911704719784,-0.12220433600304552
3,392
Abnormality of fontanelles
17
52
2.584265
0.009759
O75381,Q9Y5Y5,P36543,O75718,P20674,Q08J23,Q9Y487,Q15436,O75844,P56589,Q8NCH0,Q9Y619,Q32P28,O15111,Q2M1P5,P40855,Q9H9E3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
280,130,473,454,358,361,235,435,50,464,22,87,249,312,354,93,356
2456,312,1727,280,2438,3196,454,50,844,2623,516,358,2923,1763,2735,2646,473,2698,3175,2236,93,2002,694,3289,1272,1835,3292,1706,464,2120,711,1381,861,361,2532,2722,435,1741,1466,354,249,1445,22,1473,1640,3056,807,356,1456,235,130,87
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3,392
Peptide binding
19
74
2.581263
0.009844
O00264,O14773,Q15392,Q9UHB9,Q6P179,O43731,Q9Y287,P24390,Q9UHV9,Q9NXR7,P55786,Q9Y4U1,Q9NZ08,Q8WTV0,Q15388,P40855,Q99471,Q08209,O15212
Functions
GO Molecular function
msigdb_gomf
0,140,273,404,16,149,414,28,157,294,308,325,191,452,342,93,223,232,247
0,1588,2365,3174,140,247,1589,149,691,1907,1702,1022,2372,1488,1858,1627,2375,1270,1228,3278,2504,28,3189,1628,2458,2769,1233,1234,2505,93,742,2275,3219,2003,1272,2004,2313,1807,308,1130,2834,907,2576,1772,2172,3136,232,2144,1329,2509,3349,342,273,16,1607,641,452,1335,1101,2709,223,2843,965,2738,479,294,191,404,157,534,830,414,1620,325
4.357302273053826,-0.07650252744056436,-0.47629050319229616,-1.1088728099650214,1.8808822458505576,1.4328440873723212,-0.07650252744056436,1.8253608767518077,0.6112661660954188,-0.24461259530598548,-0.13746249502499586,0.3002284258115414,-0.47629050319229616,-0.015734964198557747,-0.21393665194747497,-0.09172438937674851,-0.47629050319229616,0.10523221520582753,0.13535733730271166,-1.4175431235378706,-0.5541621697421181,3.4241806746156223,-1.1249806168260381,-0.09172438937674851,-0.522974005179062,-0.7424180239388641,0.13535733730271166,0.13535733730271166,-0.5541621697421181,2.2930986183056987,0.5523870051126312,-0.4297244698805092,-1.2057460042171027,-0.2907199213981397,0.10523221520582753,-0.2907199213981397,-0.44523349939724377,-0.18331016512462858,1.2767238749913556,0.21046898250401078,-0.7897895963070047,0.38958597328502204,-0.6010440292225467,-0.1680153718164889,-0.3832747697389823,-1.0606389558982219,1.4893416625418183,-0.3678171946564402,0.07506070309973252,-0.5541621697421181,-2.052724964852463,1.205389452082045,1.362018084052379,3.7217303548789196,-0.07650252744056436,0.6992699083324146,0.9755194520783873,0.07506070309973252,0.24043388497129026,-0.6794490424983824,1.5175365324543044,-0.7897895963070047,0.3598443506231174,-0.710906100634738,0.9321417422805507,1.3194125750424903,1.6299606471660821,1.0763911704719784,1.8114594151764092,0.8596469929949846,0.47854849943901234,1.062010089223635,-0.07650252744056436,1.2482182125944992
3,392
Diseases of signal transduction by growth factor receptors and second messengers
37
151
2.580451
0.009867
O95684,Q9NRY5,P30154,P10644,P31749,P31946,Q16537,Q13555,O95429,P28072,P67936,P40763,P30153,Q96PU8,O15111,P49720,Q9UL46,O00231,P33176,Q9UBV2,P49721,P21359,P35269,Q92734,P39880,P13984,Q16543,P56545,P51797,Q96RT1,P31751,P28070,P20618,P49589,Q14203,P61289,Q06323
Processes and pathways
Reactome Pathways
msigdb_reactome
256,8,262,397,23,535,550,34,163,164,295,307,564,187,312,445,64,193,455,335,75,204,583,467,595,216,222,602,228,615,101,227,236,367,491,116,121
2876,193,3012,1878,1318,872,1621,312,1251,1126,1396,690,3249,1701,1593,1184,2194,163,256,844,3015,610,1626,1520,397,904,216,1230,2524,3204,1039,1056,236,204,2830,929,1231,1832,1659,2062,1978,1322,2168,227,164,1145,2063,1764,564,262,1494,23,101,1552,535,455,1595,1189,583,1372,1805,1373,595,307,2750,788,2002,759,1010,2169,1298,367,445,75,2003,837,1497,3197,1211,228,1299,1461,602,1096,116,3256,889,2141,1836,2791,3051,2460,819,1554,2142,1837,295,1574,2701,1381,1862,2006,121,661,1407,2007,3371,1633,1275,1382,34,3081,1684,491,2532,1044,2888,1353,550,222,1064,1813,2893,1215,2653,2486,1607,2072,1384,2794,2418,2564,467,2356,1415,187,615,825,1962,685,655,2688,2658,8,2900,3131,335,3008,64,1390,1876
-0.8214403202477919,1.6159385005727454,-0.9326628846066711,-0.22926842223566576,0.07506070309973252,0.4192837063531287,-0.09172438937674851,1.262475712405316,0.12030055776561276,0.21046898250401078,0.0297158455536117,0.6112661660954188,-1.319461443687167,-0.13746249502499586,-0.07650252744056436,0.16543634416126807,-0.3987451465185144,1.741824390244023,1.404541025827467,0.4489377993753778,-0.9326628846066711,0.7285214102943242,-0.09172438937674851,-0.030908945292574343,1.0763911704719784,0.38958597328502204,1.5316205651807586,0.13535733730271166,-0.5697761307887955,-1.1572413371765422,0.2852966167197613,0.2703536119434672,1.4752307813901213,1.573819316272094,-0.7897895963070047,0.37472066384711566,0.13535733730271166,-0.19861724574074396,-0.1069583132087397,-0.32152087180770866,-0.2753383056546045,0.07506070309973252,-0.3832747697389823,1.5034435722199273,1.741824390244023,0.1954695077304166,-0.32152087180770866,-0.1680153718164889,0.8014705690921952,1.3762015415441697,-0.015734964198557747,3.502130832268083,2.197563227073385,-0.04609484197467206,0.8451180196791206,0.961070082526128,-0.07650252744056436,0.16543634416126807,0.7723215542957492,0.044842523349634685,-0.18331016512462858,0.044842523349634685,0.7577317502408601,1.2767238749913556,-0.726655180985889,0.5081160512050436,-0.2907199213981397,0.5376406969420575,0.31514907160504646,-0.3832747697389823,0.09015227518848501,1.1481522657707446,0.989958989232039,2.5100333281525296,-0.2907199213981397,0.4637485581792443,-0.015734964198557747,-1.141103441123685,0.1504025880743201,1.5034435722199273,0.09015227518848501,-0.00057286259791032,0.7431317115189636,0.24043388497129026,2.046646024024901,-1.3357688144594548,0.4044403103634737,-0.3678171946564402,-0.19861724574074396,-0.7581946761452075,-0.9645695362458719,-0.522974005179062,0.47854849943901234,-0.04609484197467206,-0.3678171946564402,-0.19861724574074396,1.3051922828493479,-0.06129269053099454,-0.6794490424983824,0.044842523349634685,-0.21393665194747497,-0.2907199213981397,2.0191011953082207,0.6699770190108111,0.0297158455536117,-0.2907199213981397,-2.5907524840201,-0.09172438937674851,0.10523221520582753,0.044842523349634685,3.2806564295146425,-0.9965341580527574,-0.12220433600304552,0.9031737594044319,-0.5697761307887955,0.2852966167197613,-0.8214403202477919,0.0599574641453926,0.8305789759854734,1.5175365324543044,0.2703536119434672,-0.18331016512462858,-0.8214403202477919,0.1504025880743201,-0.6480464817522166,-0.5385614757094254,-0.07650252744056436,-0.32152087180770866,0.044842523349634685,-0.7581946761452075,-0.4918385618163464,-0.5854034026110678,0.9466108546188425,-0.46075549648323305,0.0297158455536117,1.6439740384202233,0.7285214102943242,0.47854849943901234,-0.25996921007055324,0.6259595854721536,0.6846286512595186,-0.6637409727699075,-0.6480464817522166,3.9905008372082813,-0.8214403202477919,-1.0445906823532496,1.233951351838413,-0.9167311709438607,2.671459958677549,0.044842523349634685,-0.21393665194747497
3,392
Mitochondrial myopathy
10
32
2.574853
0.010028
P00846,Q9Y6M9,O43676,O75306,Q96CU9,Q7LG56,Q8IUX1,Q9BUK6,P03886,P00403
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,394,38,417,402,174,250,57,220,92
2191,38,707,2569,417,924,795,92,33,220,997,2402,3255,3275,2861,953,1813,174,466,250,778,1386,402,1284,1615,57,2424,643,944,1651,1674,394
-0.3987451465185144,3.149476125453242,0.596562227640058,-0.6010440292225467,1.0476193288474605,0.37472066384711566,0.4933376536617622,2.2930986183056987,3.2806564295146425,1.5175365324543044,0.3300585863237035,-0.4918385618163464,-1.3357688144594548,-1.4011564023133367,-0.8056079589553966,0.3598443506231174,-0.18331016512462858,1.6999404710130017,0.9466108546188425,1.4328440873723212,0.5228837222779321,0.044842523349634685,1.0763911704719784,0.10523221520582753,-0.07650252744056436,2.725031627796951,-0.4918385618163464,0.6992699083324146,0.37472066384711566,-0.09172438937674851,-0.1069583132087397,1.0907625977334081
3,392
Nervous system process
23
104
2.563019
0.010377
Q15555,O00264,Q9Y6M9,Q9Y5J9,O14773,P17900,P31749,Q9H6K4,P04062,O75844,P07196,Q7L576,P50897,Q13641,P61160,Q14108,P21359,Q9BPZ3,Q11206,Q14168,Q08209,Q14203,Q9NWW5
Processes and pathways
GO Biological process
msigdb_gobp
504,0,394,268,140,146,23,156,32,50,178,309,55,56,449,74,204,89,353,97,232,491,118
2592,0,140,707,1972,1346,2639,783,693,2266,2439,50,1430,1543,32,3274,2715,513,2457,2110,178,2269,573,146,1433,2716,204,1118,1322,1628,2063,1254,23,1629,2749,1765,2002,2857,1374,3361,1376,837,1272,55,3197,1191,449,2037,2314,3178,2120,1770,983,232,2239,353,1302,1329,1601,56,74,97,491,1134,2533,2242,504,3268,863,985,309,1556,3067,2467,1783,3334,2418,2777,1416,2129,2288,684,1362,1050,1928,990,89,2048,1261,2492,2738,156,1965,3158,1822,118,1825,2919,919,884,2938,268,2080,394
-0.6166980548909288,4.357302273053826,1.8808822458505576,0.596562227640058,-0.2753383056546045,0.0599574641453926,-0.6480464817522166,0.5081160512050436,0.6112661660954188,-0.4297244698805092,-0.5073997148873077,2.8318251529978857,0.014577395414097777,-0.04609484197467206,3.2937373551059523,-1.4011564023133367,-0.6951707365076549,0.8741659228684505,-0.522974005179062,-0.3523723803792923,1.6859618908518097,-0.4297244698805092,0.7869011513881382,1.8531384170199579,0.014577395414097777,-0.6951707365076549,1.573819316272094,0.22545709717825904,0.07506070309973252,-0.09172438937674851,-0.32152087180770866,0.12030055776561276,3.502130832268083,-0.09172438937674851,-0.726655180985889,-0.1680153718164889,-0.2907199213981397,-0.8056079589553966,0.044842523349634685,-2.3627786138613653,0.044842523349634685,0.4637485581792443,0.10523221520582753,2.725031627796951,-1.141103441123685,0.16543634416126807,0.9755194520783873,-0.30611409685763147,-0.44523349939724377,-1.1088728099650214,-0.3523723803792923,-0.1680153718164889,0.3449570020292946,1.4893416625418183,-0.4142283661153823,1.1910943651123755,0.09015227518848501,0.07506070309973252,-0.07650252744056436,2.725031627796951,2.5370126379799847,2.2522022302138622,0.9031737594044319,0.21046898250401078,-0.5697761307887955,-0.4142283661153823,0.888674836109678,-1.3684308687904816,0.4341161923697676,0.3449570020292946,1.2767238749913556,-0.04609484197467206,-0.9805445753920402,-0.522974005179062,-0.1680153718164889,-1.7654688962679639,-0.4918385618163464,-0.7424180239388641,0.0297158455536117,-0.3523723803792923,-0.4297244698805092,0.6259595854721536,0.0599574641453926,0.2852966167197613,-0.24461259530598548,0.3449570020292946,2.3339245064028766,-0.30611409685763147,0.12030055776561276,-0.5385614757094254,-0.710906100634738,1.8114594151764092,-0.25996921007055324,-1.0767020329756654,-0.18331016512462858,2.0328776982252563,-0.18331016512462858,-0.8372867282398355,0.38958597328502204,0.4192837063531287,-0.8531472312752075,1.3762015415441697,-0.32152087180770866,1.0907625977334081
3,392
Protein insertion into membrane
13
29
2.562065
0.010405
Q9P0J0,P46379,Q8N8Q8,Q9Y5J9,Q9NS69,Q8N4V1,Q9Y512,Q15006,O43681,Q15070,Q9P0I2,O14737,Q15629
Processes and pathways
GO Biological process
msigdb_gobp
522,319,291,268,42,529,365,143,523,81,345,341,59
341,523,545,1702,1626,1371,2235,319,2834,2446,143,81,59,1813,2283,3379,529,2415,291,1719,822,1363,42,345,522,1826,365,3101,268
1.205389452082045,0.8596469929949846,0.8305789759854734,-0.13746249502499586,-0.09172438937674851,0.044842523349634685,-0.4142283661153823,1.2482182125944992,-0.7897895963070047,-0.5073997148873077,1.8670145354751024,2.442452416251786,2.6982604715752156,-0.18331016512462858,-0.4297244698805092,-3.4094648282561173,0.8596469929949846,-0.4918385618163464,1.3194125750424903,-0.13746249502499586,0.47854849943901234,0.0599574641453926,3.0704404222415245,1.205389452082045,0.8741659228684505,-0.18331016512462858,1.162475796263921,-1.0125383355924664,1.3762015415441697
3,392
SLC superfamily of solute carriers
9
48
2.558419
0.010515
P08195,Q70HW3,Q8TAD4,Q8NEW0,Q9H2D1,Q9BSK2,Q9Y6C9,Q9Y619,Q9UBX3
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
71,44,110,109,15,114,213,87,26
2663,219,2439,1253,1623,1976,2571,71,3378,997,1549,1551,2905,2648,2005,1256,1681,1661,2386,562,2146,1445,2890,44,961,3306,109,110,508,1472,1083,1928,393,114,2492,15,702,3293,991,1104,1020,2473,631,26,1342,87,213,1567
-0.6637409727699075,1.5175365324543044,-0.5073997148873077,0.12030055776561276,-0.09172438937674851,-0.2753383056546045,-0.6010440292225467,2.5774251672985713,-3.3346573519697245,0.3300585863237035,-0.04609484197467206,-0.04609484197467206,-0.8372867282398355,-0.6480464817522166,-0.2907199213981397,0.12030055776561276,-0.12220433600304552,-0.1069583132087397,-0.47629050319229616,0.8160298348526115,-0.3678171946564402,0.014577395414097777,-0.8214403202477919,3.0043870268143222,0.3598443506231174,-1.5657532843548536,2.1016379298886707,2.1016379298886707,0.888674836109678,-0.00057286259791032,0.2553993789324403,-0.24461259530598548,1.0907625977334081,2.074158219188792,-0.5385614757094254,3.760293155258865,0.6112661660954188,-1.483251123536119,0.3449570020292946,0.24043388497129026,0.31514907160504646,-0.522974005179062,0.7139008185990915,3.476173526807814,0.07506070309973252,2.4018122550596814,1.5456956922416358,-0.04609484197467206
3,392
Endoplasmic reticulum golgi intermediate compartment membrane
9
29
2.555008
0.010619
Q15363,O15260,Q13190,O14653,Q9Y282,O95070,Q9Y3B3,Q96GC9,P24390
Localization
GO Cellular component
msigdb_gocc
386,65,165,289,14,269,124,186,28
289,1568,65,971,2060,269,28,3189,565,3238,1191,1172,1772,2172,1682,450,1683,165,386,2869,700,186,824,1418,3332,1900,14,1139,124
1.3194125750424903,-0.06129269053099454,2.644629964151358,0.3449570020292946,-0.32152087180770866,1.362018084052379,3.4241806746156223,-1.1249806168260381,0.8014705690921952,-1.2706332542898442,0.16543634416126807,0.18045863946931265,-0.1680153718164889,-0.3832747697389823,-0.12220433600304552,0.9755194520783873,-0.12220433600304552,1.741824390244023,1.1051243960353279,-0.8056079589553966,0.6112661660954188,1.6439740384202233,0.47854849943901234,0.0297158455536117,-1.7320119479177913,-0.22926842223566576,3.7859704508763934,0.21046898250401078,1.9915235827542386
3,392
Recruitment of numa to mitotic centrosomes
24
41
2.551156
0.010737
O95684,Q9BSJ2,O15078,Q13561,Q9H6D7,P41208,P62258,Q9BUF5,P53350,P61163,P06493,Q9NVX0,P30153,P68371,O94927,O75935,Q15691,P23258,Q68CZ6,P04350,Q14203,Q15154,Q96CS2,Q13885
Processes and pathways
Reactome Pathways
msigdb_reactome
256,780,645,650,21,278,283,426,671,801,796,316,564,696,318,197,848,582,465,482,491,763,373,503
645,972,197,318,256,482,796,854,1626,2787,582,564,1254,278,1374,671,801,1131,283,1326,696,1662,650,503,2999,491,3180,3020,763,848,3287,465,1716,1357,373,780,426,2048,21,316,3143
0.6846286512595186,0.3449570020292946,1.6019075774365181,1.2482182125944992,1.404541025827467,0.9176627193149094,0.4933376536617622,0.4341161923697676,-0.09172438937674851,-0.7581946761452075,0.7723215542957492,0.8014705690921952,0.12030055776561276,1.3478254524900601,0.044842523349634685,0.655314983080957,0.4933376536617622,0.21046898250401078,1.3336236238545365,0.07506070309973252,0.6112661660954188,-0.1069583132087397,0.6846286512595186,0.888674836109678,-0.9167311709438607,0.9031737594044319,-1.1088728099650214,-0.9326628846066711,0.5376406969420575,0.4489377993753778,-1.4503647779093343,0.9466108546188425,-0.13746249502499586,0.0599574641453926,1.1338192053070948,0.5228837222779321,1.0476193288474605,-0.30611409685763147,3.5669108013937043,1.262475712405316,-1.0606389558982219
3,392
Mitochondrial envelope
168
343
7.530221
0
O43169,O43676,P14406,Q5VT66,Q8N4H5,Q8WY22,Q9H061,O43615,Q9NZ45,Q9P0S2,O60313,P08574,O14949,Q5XKP0,O75964,Q96A26,Q9NS69,Q9Y584,Q9UKU0,P62072,Q14318,O14925,Q7Z7H8,Q9H4I9,O60830,P82650,P35232,Q13505,Q15070,Q9NX63,O00165,Q70HW3,P45880,Q8N5K1,Q12981,Q9UBX3,Q99595,Q9Y277,Q8N2A8,P43304,Q9H3K2,P21796,Q9BUR5,O75746,P15954,Q9Y241,Q14197,Q86Y39,Q8TB36,Q8N442,Q8IXI1,P33121,P57105,Q96H78,O00264,P36404,P22830,O94826,Q9H2D1,Q16891,Q9Y6M9,P03886,Q15388,P13073,P00846,Q9UDW1,Q9Y2R0,O95202,Q9NUQ2,Q9Y255,Q9UDX5,O75208,O95563,O95674,Q8N8Q8,Q9NZJ7,Q8NBN7,Q8NI60,Q9Y6N1,P09601,P12235,Q9NQZ5,P52789,Q8WWC4,Q9H4A6,Q8IYU8,P16260,Q9Y5J9,Q9NX47,P23786,P12236,Q9Y619,P30536,Q53H12,Q9NPL8,Q9BSK2,Q9UG56,Q9Y320,Q9Y371,P50416,Q07820,Q96IX5,Q8WUK0,P52888,P56378,P53701,Q9NVI7,Q7KZN9,Q6UXV4,Q99623,P21912,Q9BXK5,Q96AQ8,Q9NX14,P00387,O75947,Q6NUK1,Q86UT6,Q99643,O96008,O75880,P56385,Q9HC21,Q9BQT8,Q9Y512,Q96ER9,P22695,Q9H300,P24539,Q9BYD1,Q9BPX6,O95139,Q9Y5J6,P20674,O75431,O15228,Q07812,Q5T9A4,Q9BRJ2,Q8IWA4,Q10713,Q9Y6C9,Q9NVS2,P09669,O14548,Q6P4A7,O95167,Q9H9P8,Q8NE86,P05141,Q9BUB7,Q9Y3D9,Q9Y5Z9,Q9UJZ1,Q8N183,O95831,Q7Z434,P40939,P33897,Q9HD33,Q96NB2,Q9UH62,Q96CU9,Q9Y276,O75306,Q9BWH2,Q567V2,O75323
Localization
GO Cellular component
msigdb_gocc
0,1,2,517,4,5,6,520,9,10,521,522,13,16,17,20,21,23,25,26,536,29,34,38,37,544,543,41,42,557,552,47,50,564,562,61,64,66,67,578,69,70,71,575,577,74,590,77,593,592,591,585,84,87,88,601,600,598,99,602,625,103,620,112,115,120,122,124,125,126,127,128,129,138,139,140,141,143,148,152,158,170,171,172,173,175,176,181,183,182,185,188,197,204,208,210,212,216,217,213,222,223,226,227,237,243,247,251,250,260,266,283,282,286,284,288,290,296,302,300,298,306,310,313,323,325,329,333,330,343,342,338,346,349,348,353,354,355,356,364,361,377,376,371,369,378,394,408,406,403,412,414,415,422,419,416,431,427,426,459,457,468,465,477,483,500,504,508
552,88,1529,994,3189,3208,369,1625,29,13,353,1471,0,918,520,1695,1,2641,1253,1322,521,1094,37,1351,128,700,483,508,1597,348,1451,1136,2041,3103,575,298,288,17,1982,598,338,1201,394,1956,1182,124,671,129,1697,138,416,2439,300,284,1598,115,103,1666,403,1403,2335,1300,522,2959,2753,152,371,727,2043,922,1987,1074,158,185,2252,112,2,1326,577,176,1006,2336,761,886,1502,349,70,266,2161,329,600,1115,182,330,1836,3187,1733,197,1700,785,585,426,1569,543,601,985,730,1736,947,427,2598,578,50,1808,2314,1287,2495,213,1099,867,171,2758,227,617,243,1081,731,1118,1778,1675,237,306,84,26,544,1608,906,2891,2602,2140,1744,732,703,2194,869,354,222,361,1543,562,871,1266,3201,873,41,590,536,42,2964,620,1648,1514,2289,2426,1390,602,674,1418,204,504,889,663,355,1419,517,16,854,2427,290,1581,378,2762,250,804,47,251,1969,431,2683,34,296,776,77,364,591,1585,175,1654,419,67,592,4,564,139,2091,1365,141,875,406,143,593,1882,226,172,766,5,1615,999,1244,20,1173,282,2266,1123,1103,465,2744,325,1915,2296,694,87,911,223,457,1271,962,933,2326,1245,64,260,302,342,1104,313,356,1752,210,1718,412,1421,71,3219,500,1105,283,1422,343,2208,1295,750,2929,936,6,1296,99,1976,938,333,69,173,38,1196,752,2301,678,753,408,1343,310,459,712,1107,208,808,1224,170,643,1593,3160,2381,21,125,739,809,247,376,1108,1397,286,183,557,2067,9,140,1658,1131,1252,10,755,61,120,127,212,468,778,422,25,74,126,477,66,2984,1689,122,2356,216,217,898,2519,414,1281,323,23,346,181,415,188,377,625,148,811
0.6866340160886069,2.2747847087222794,-0.1058920750579502,0.22961279842123378,-2.408050912801986,-4.45856096536647,1.0224874166341895,-0.15011234602282414,3.361075633693647,4.196501680534049,1.0779181486196767,-0.07647199667296625,4.3291217026971225,0.28734545070934525,0.7430072800978298,-0.1796530741697238,4.3291217026971225,-0.674363810312437,0.055331969068424594,0.011503046829603012,0.7430072800978298,0.15719497235672153,3.2106974716483787,-0.003129968688779517,1.9452503290298178,0.4880301099656987,0.8132470889449575,0.7711332727194923,-0.13536018457472698,1.0917521341398324,-0.06177987491864927,0.12814857045825676,-0.3430078305713249,-1.3257142494377188,0.6442470592213966,1.2433090578397443,1.2844490111299678,3.7453603850636794,-0.313194785097642,0.6159377018946759,1.1193918429266982,0.08449317262514162,0.9808141312665962,-0.29830712100880136,0.09905645771621088,1.9717947009390235,0.5307604103957996,1.9452503290298178,-0.1796530741697238,1.8920646818638314,0.9390541618071563,-0.553133878075549,1.2433090578397443,1.298144113646831,-0.13536018457472698,2.0247872950224237,2.090849287701112,-0.164876629692285,0.9669038074280564,-0.03243127960906722,-0.4928382444842881,0.02612435090038817,0.7430072800978298,-0.9813049356287264,-0.7505734286242784,1.8120416545482296,1.0224874166341895,0.4594902255077705,-0.3430078305713249,0.28734545070934525,-0.313194785097642,0.1717011182043829,1.7853014752695062,1.6241579565962334,-0.447753880325114,2.0380155210262614,4.3291217026971225,0.011503046829603012,0.6442470592213966,1.6780073418899184,0.2151517460221033,-0.4928382444842881,0.43090764101721113,0.3161453056172049,-0.09117605087284349,1.0917521341398324,2.5995589664368004,1.3528340672655668,-0.4027859480941016,1.1331976156562682,0.6159377018946759,0.14267746792433023,1.6376330607839327,1.1331976156562682,-0.23888123943057013,-2.3231611916154886,-0.19444171825613035,1.570171930412102,-0.1796530741697238,0.4022821085379622,0.6300975384411448,0.9251147879781412,-0.1206201069740683,0.7007425622241883,0.6159377018946759,0.24406266179274372,0.4594902255077705,-0.19444171825613035,0.27292895481255514,0.9251147879781412,-0.6439755827313389,0.6442470592213966,2.907101064760008,-0.2240557615419202,-0.47779711418441184,0.04073397966432928,-0.5833609844142108,1.5160479135785023,0.15719497235672153,0.330528729857457,1.704881209746608,-0.7505734286242784,1.4617845329488237,0.6017675204564823,1.420994700450676,0.1717011182043829,0.4594902255077705,0.14267746792433023,-0.20924260096857328,-0.164876629692285,1.4346001455642394,1.2295774465746885,2.3661898889393695,3.448371427949981,0.7007425622241883,-0.13536018457472698,0.3017508900780304,-0.8886275567160946,-0.6439755827313389,-0.387822311164995,-0.19444171825613035,0.4594902255077705,0.4880301099656987,-0.4177623935728443,0.330528729857457,1.0779181486196767,1.4889337304892023,1.06407470918364,-0.1058920750579502,0.6725152692738572,0.330528729857457,0.055331969068424594,-3.270047344047104,0.330528729857457,3.1099250993926355,0.6300975384411448,0.7148409361035052,3.0972988744230174,-0.9813049356287264,0.6017675204564823,-0.15011234602282414,-0.09117605087284349,-0.46276900728826853,-0.5380402143385864,-0.01777473199075143,0.6159377018946759,0.5307604103957996,-0.03243127960906722,1.5566539160615283,0.7851812068774792,0.3161453056172049,0.544982758232892,1.0779181486196767,-0.03243127960906722,0.7570753063743473,3.7822378308851308,0.344901195162577,-0.5380402143385864,1.2844490111299678,-0.1206201069740683,1.0086059102080356,-0.7505734286242784,1.4073803914068117,0.38795315862879387,2.9706691886854455,1.4073803914068117,-0.29830712100880136,0.9251147879781412,-0.6895783192988665,3.2860025236144654,1.270744816588314,0.4166002588713612,2.431254128827567,1.06407470918364,0.6300975384411448,-0.1206201069740683,1.6914484940680552,-0.15011234602282414,0.9390541618071563,2.62534308033295,0.6300975384411448,4.3291217026971225,0.6725152692738572,1.8920646818638314,-0.35793329427295245,-0.003129968688779517,1.8654231014435778,0.330528729857457,0.9669038074280564,1.8520900546502441,0.6300975384411448,-0.2537190743102173,1.4753635194517039,1.704881209746608,0.43090764101721113,4.3291217026971225,-0.13536018457472698,0.22961279842123378,0.06991835486739327,3.5973077301556384,0.11360824532721736,1.3118301474062795,-0.447753880325114,0.14267746792433023,0.15719497235672153,0.8552713566510017,-0.7353039946740639,1.160781120599868,-0.2685693060796182,-0.46276900728826853,0.5022841164890406,2.3140036938827615,0.3017508900780304,1.4889337304892023,0.8692596729318535,0.055331969068424594,0.27292895481255514,0.28734545070934525,-0.47779711418441184,0.06991835486739327,2.663965486017274,1.3801250919931503,1.2433090578397443,1.1193918429266982,0.15719497235672153,1.2020866418225167,1.0779181486196767,-0.19444171825613035,1.5295919290991515,-0.1796530741697238,0.9529838262623884,-0.03243127960906722,2.5995589664368004,-6.456585704094945,0.7992191364595662,0.15719497235672153,1.3118301474062795,-0.03243127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3,220
Nuclear outer membrane endoplasmic reticulum membrane network
154
344
7.054847
0
Q99442,P43307,Q9NTJ5,O15269,Q9Y3B3,O95197,P61009,Q86YN1,O75881,Q2TAA5,Q9UKU0,P30519,Q9HBH5,Q9BRR6,Q86UE4,Q14318,Q9P2W9,Q9BUN8,Q9BQE5,Q9BT22,P51648,Q96AD5,P67812,Q96A33,Q8N5K1,Q12981,Q9Y282,O75844,Q8NBI6,O94874,O00400,Q9H3N1,Q9BUR5,O60725,Q15629,Q5BJH7,O60858,Q8N511,O95772,O00264,Q5VV42,O43731,Q16799,Q96PC5,Q9H2C2,Q8TB61,P57088,Q15005,O75298,Q6P1A2,Q9NQC3,Q9NUQ2,O95470,Q9NZ08,O43292,O95674,Q9NPA0,Q96AG4,Q9BRK0,Q96G23,Q8NHH9,P09601,Q07065,Q8N4V1,Q9HD20,P24390,Q9BU23,Q9Y5Y5,Q15800,P16615,Q9NX47,Q96RQ1,O95070,Q8N5M9,Q86XL3,Q9Y5M8,Q9Y320,Q16850,P56962,O14653,Q9Y2B2,Q03518,Q14534,Q6NUQ4,Q9Y4P3,Q10472,P27824,Q15041,Q9NP72,Q96JJ7,Q96KC8,Q9BVG9,O76024,A8CG34,O14735,Q4ZIN3,P16435,P38435,P35610,P61026,Q6NUK4,O15120,P00387,O14880,Q9H490,Q9NZ43,Q9UM00,Q9H6H4,Q9UBU6,Q969X5,Q9Y3A6,Q92604,O75340,Q07812,Q9HCU5,Q13438,Q06136,Q86SQ9,Q9C0D9,Q96HY6,Q9P035,O43264,O75915,Q8NF37,Q9BV10,Q9UBV2,Q9Y5Z9,Q9Y6I9,Q9Y679,P46977,Q53GQ0,P33897,Q6NUM9,Q8N2F6,Q9Y394,Q99943,Q70UQ0,Q9H0U4,Q5T9L3,Q92643,Q92575,Q14739,O75396,P51571,O14975,P50402,Q9H8Y8,P51572,Q8IV08,Q15392,Q99735,P61019,P62942,P49755
Localization
GO Cellular component
msigdb_gocc
513,3,518,519,532,15,528,19,525,538,25,24,542,27,28,536,31,32,33,39,44,566,52,53,564,562,56,57,58,568,62,65,71,72,75,76,78,80,85,88,91,92,94,97,98,104,105,106,108,113,117,125,133,135,137,138,142,144,145,150,154,152,153,161,162,164,168,174,177,179,183,187,189,194,193,209,216,215,214,225,233,228,229,239,242,238,236,244,254,258,259,263,262,264,265,267,269,270,271,280,281,276,284,287,292,314,316,334,335,341,344,340,347,354,358,362,360,367,375,380,382,392,393,396,398,413,415,424,423,417,430,426,434,435,436,441,439,442,447,448,456,454,452,453,460,470,476,485,488,495,499,494,503,511
657,757,2390,264,88,62,1529,1692,644,1693,225,645,265,287,995,460,2859,1694,276,1093,519,758,392,137,1800,918,92,699,1727,612,1094,1049,72,883,78,108,347,452,3133,760,57,1376,525,393,262,568,743,979,980,189,15,1004,133,1984,3134,1697,138,85,1202,865,284,2440,921,1532,884,2362,1501,1183,1256,152,646,922,1076,269,179,761,1257,1634,2190,164,762,946,2980,236,2694,2674,24,1079,2469,585,426,1807,271,614,3100,270,2284,2598,1571,3,417,2255,3018,1740,1261,849,511,2316,470,1434,453,485,44,772,798,2937,2852,2341,1118,1605,214,105,1435,1540,1868,528,494,280,1993,2759,1460,1209,2679,2760,851,1262,503,2083,2223,52,2109,228,1904,832,360,153,354,2474,238,1643,690,562,672,362,2535,1645,1875,2401,536,229,454,106,2322,244,950,2655,1308,1239,1783,495,1941,75,1907,177,1707,94,215,538,2881,267,430,1060,76,1013,684,447,998,91,2059,954,281,434,1061,239,891,113,735,571,765,1942,3115,641,439,2965,2291,3149,367,28,2119,193,776,19,488,2029,1653,691,435,2479,161,80,564,194,1062,633,58,396,692,154,1172,2507,104,838,1882,693,1038,2821,960,2032,456,340,448,2482,2901,736,341,53,566,144,1125,3098,150,1040,380,258,259,594,97,1271,187,710,653,513,2035,806,2207,499,441,33,145,27,1089,1041,39,168,32,71,398,655,263,749,677,375,768,2122,442,98,2351,975,65,292,2796,334,476,542,358,162,254,712,142,117,2724,518,125,916,183,1130,1756,769,135,314,382,740,840,2462,3197,31,1494,1722,335,413,1022,1023,25,316,965,3029,56,233,216,2812,436,344,532,1796,242,2413,209,174,415,1887,3084,423,781,424
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3,220
Organelle subcompartment
173
417
6.561307
0
Q99442,P43307,Q9NTJ5,O15269,Q9Y3B3,O95197,P61009,Q86YN1,O75881,Q2TAA5,Q9UKU0,P30519,Q9HBH5,Q9BRR6,Q86UE4,Q14318,Q9P2W9,Q9BUN8,Q9BQE5,Q9BT22,P51648,Q96AD5,P67812,Q96A33,Q8N5K1,Q8N2H4,Q9Y282,O75844,Q8NBI6,Q00765,Q12981,O94874,O00400,Q9H3N1,Q96A57,Q9BUR5,O60725,O95249,Q15629,Q5BJH7,O60858,Q8N511,O95772,Q8NBN3,O00264,Q5VV42,O43731,Q16799,Q96PC5,Q9H2C2,Q8TB61,P57088,Q15005,O75298,Q6P1A2,Q9NQC3,O60499,Q9NUQ2,O95470,Q9NZ08,O43292,O95674,Q9NPA0,Q96AG4,Q9BRK0,Q96G23,Q8NHH9,P09601,Q07065,O00461,Q8N4V1,Q9HD20,P24390,Q9BU23,Q9H4A6,Q9Y5Y5,Q15800,Q9NPR9,P16615,Q9NX47,Q96RQ1,O95070,Q8N5M9,Q86XL3,Q9Y5M8,Q9Y320,Q16850,P56962,Q9HC07,O14653,Q9Y2B2,Q03518,Q14534,Q6NUQ4,Q9Y4P3,Q10472,P27824,Q15041,Q9NP72,Q96JB2,O43752,Q96JJ7,Q96KC8,Q9BVG9,O76024,A8CG34,O14735,Q4ZIN3,P16435,P38435,P35610,P61026,Q6NUK4,O15120,P00387,O14880,Q9H490,Q9BXS4,Q9NZ43,Q9UM00,Q9H6H4,Q9UBU6,Q969X5,Q9Y3A6,Q92604,O75340,Q07812,Q9HCU5,Q10713,Q13438,Q06136,Q86SQ9,Q9C0D9,Q12846,Q96HY6,Q9P035,O43264,O75915,Q8NF37,Q8TBA6,Q9BV10,P50570,Q9UBV2,Q9Y5Z9,Q9Y6I9,Q9Y679,P46977,P98194,Q53GQ0,P33897,Q6NUM9,Q8N2F6,Q9Y394,Q99943,Q70UQ0,Q9H0U4,Q5T9L3,Q92643,Q92575,Q14739,O75396,P51571,O14975,P50402,Q9H8Y8,Q12893,P51572,Q8IV08,Q15392,Q99735,P61019,P62942,P49755
Localization
GO Cellular component
msigdb_gocc
513,3,518,519,532,15,528,19,525,538,25,24,542,27,28,536,31,32,33,39,44,566,52,53,564,563,56,57,58,59,562,568,62,65,68,71,72,73,75,76,78,80,85,86,88,91,92,94,97,98,104,105,106,108,113,117,118,125,133,135,137,138,142,144,145,150,154,152,153,159,161,162,164,168,173,174,177,178,179,183,187,189,194,193,209,216,215,214,221,225,233,228,229,239,242,238,236,244,254,253,249,258,259,263,262,264,265,267,269,270,271,280,281,276,284,287,292,309,314,316,334,335,341,344,340,347,354,358,361,362,360,367,375,372,380,382,392,393,396,397,398,410,413,415,424,423,417,429,430,426,434,435,436,441,439,442,447,448,456,454,452,453,460,470,476,478,485,488,495,499,494,503,511
657,757,2390,264,88,62,1529,2414,159,1692,644,1693,225,645,265,782,287,995,460,1694,276,1093,519,758,392,137,1800,918,92,1954,249,3089,699,1727,612,1094,118,1049,72,883,2714,78,1374,108,347,452,3133,2873,760,57,1376,525,393,262,568,743,979,980,189,15,73,1004,1096,133,1984,3134,1697,138,85,1202,865,284,1233,2440,921,1532,3023,884,1501,1183,1256,885,152,1113,646,922,3099,1076,1931,269,179,761,1257,1431,2890,1634,2190,164,762,946,2980,236,2312,2694,2674,24,1079,2469,585,426,1807,271,614,3100,270,2284,718,2598,3,1505,417,2255,3018,1740,1261,849,511,470,410,1434,949,453,485,44,772,798,2877,1962,2937,2852,2341,1118,1605,214,105,1435,1540,1868,2258,528,494,280,1993,2759,1460,1209,2679,2760,2650,1262,503,2083,2223,52,2447,429,2938,59,2193,2109,228,1904,832,360,153,354,1009,928,2474,238,1083,361,1643,372,478,690,562,672,362,2535,618,1645,1875,2401,536,229,454,1170,1338,106,2322,244,950,2655,1308,2582,1239,1783,495,1941,75,1907,177,1707,2086,94,215,538,2881,1516,267,430,1060,76,1013,684,447,998,2605,91,953,2059,954,281,434,1061,239,891,113,735,571,765,1942,3115,641,439,2965,2291,3149,367,28,2119,193,776,19,488,1484,2029,1653,691,435,563,2479,161,80,564,194,1062,633,58,86,396,692,154,1172,2507,104,397,838,1882,693,1038,2821,960,2705,2032,1883,456,340,448,2482,2901,736,341,53,68,566,144,1125,3098,150,1040,380,253,258,259,1127,2823,594,97,1271,187,710,653,513,2035,806,2207,499,441,2297,33,145,27,1089,1041,1524,39,1066,168,32,71,398,655,263,749,1222,309,1525,677,1156,3003,375,768,2122,442,98,2351,975,65,292,173,2796,334,476,2328,1342,542,221,358,162,254,712,142,178,117,2637,2724,518,125,916,183,609,1130,1756,769,135,314,382,740,840,2462,3197,31,1494,1722,335,413,1022,1023,3193,25,316,1497,965,3029,822,56,1279,233,216,2812,436,1828,344,532,1796,242,209,2277,174,415,1887,3084,423,781,424
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3,220
Membrane protein complex
117
300
5.730454
0
O43676,P14406,Q8N4H5,O15269,P08574,O14949,Q9Y3B3,Q5XKP0,P61009,O75964,P05023,Q9NS69,Q9Y584,P62072,O14925,Q9P2W9,Q9BUN8,Q4KMQ2,Q9H4I9,P35232,Q9Y5X3,Q13505,O60830,Q9NX63,Q93050,P45880,P67812,Q12981,Q99816,Q99595,Q9Y277,P15954,Q9BUR5,Q9Y487,O95249,P21796,Q86Y39,Q8N511,Q9H9H4,Q9C0H2,O94826,Q16891,Q9Y6M9,P03886,Q15005,Q15388,P13073,P00846,O60499,Q9UDW1,P09429,P54709,O43292,Q9NPA0,P12235,Q8N4V1,Q8IYU8,P12236,P63096,Q53H12,Q9Y5M8,Q9Y696,P56962,Q96IX5,O14653,Q03518,P56378,Q15041,O43752,Q6UXV4,Q99623,P21912,Q9UH99,Q9NX14,O75947,Q9H490,Q99643,O96008,P56385,Q9NZ43,Q9Y512,Q96ER9,P22695,Q9UBU6,Q9UBV8,P24539,Q9BPX6,O95139,Q9Y5J6,P20674,O75340,O75431,Q07812,Q8IWA4,Q13438,O94901,Q12846,P09669,O14548,Q9NVZ3,O95167,Q8NE86,P05141,Q9UBV2,Q9Y679,P46977,Q53GQ0,O00203,Q92643,O75396,P51571,Q96CU9,Q9NR31,Q9Y276,O75306,P62942,P49755
Localization
GO Cellular component
msigdb_gocc
1,2,4,519,522,13,532,16,528,17,526,21,23,26,29,31,32,545,38,543,559,41,37,557,565,50,52,562,574,64,66,577,71,596,73,70,77,80,608,606,598,602,625,103,106,620,112,115,118,120,626,629,137,142,158,161,175,185,203,204,209,218,214,223,225,228,237,244,249,250,260,266,275,286,288,292,302,300,306,314,323,325,329,335,336,330,342,338,346,349,347,348,354,364,362,359,372,371,369,390,394,406,403,413,423,417,430,433,448,452,453,465,467,477,483,503,511
2593,433,1427,2414,994,1692,369,1625,1693,2278,225,1161,29,13,519,758,1109,2187,137,1800,918,1695,1,1954,249,1322,1981,118,943,1563,37,700,483,347,1597,452,348,1801,1136,760,288,1072,17,598,743,359,1890,980,338,394,1956,1182,73,671,1984,3134,1429,2439,300,1598,115,3040,103,2440,921,1532,526,944,403,2361,1403,2159,1300,1631,522,1256,626,885,371,727,646,2043,1987,3099,158,185,112,2,3147,1326,577,3041,3074,1502,349,903,2851,70,266,2468,329,330,1836,2980,3187,2674,1733,1700,785,1866,2981,543,1807,985,904,1080,1736,2284,3175,2936,50,2366,417,1808,2255,1933,849,511,2495,453,2167,772,867,2937,2852,1839,2341,629,1236,1605,2049,1675,237,306,214,1435,2082,528,1480,1209,2679,2760,2650,26,503,905,2343,203,52,2938,228,1904,832,1357,354,3075,372,562,2196,672,362,1965,41,1059,2368,2401,1213,1512,1939,106,2322,244,1189,2582,620,1941,1707,2426,1390,602,674,545,430,204,889,1013,1878,998,16,2172,250,77,1216,364,175,2479,4,161,80,1062,2148,1292,406,2507,693,2704,2032,856,448,2482,565,2901,1521,1125,465,1126,325,223,1820,710,653,2509,64,260,302,3037,574,342,1919,32,71,3219,606,2122,937,3112,292,38,1274,608,1343,726,142,643,467,21,809,390,286,557,314,740,1252,2869,31,2183,1494,2638,1495,335,413,336,120,1022,275,2212,1794,964,1497,3029,477,66,1280,2389,532,780,596,1281,323,23,346,1526,209,559,3084,423,218,781,696,625
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3,220
Transporters
136
397
4.968309
0.000001
Q99442,Q8WY22,Q9H061,O60313,Q9P0S2,Q9Y3B3,P05023,Q8NE01,Q9BUN8,Q96P70,Q9H4I9,Q15070,Q70HW3,P45880,Q96A33,Q5VW38,O75844,Q9UBX3,O00400,Q9H3N1,Q96A57,Q9BUR5,Q15629,Q8N511,O60637,P57105,Q96H78,Q16799,O75192,Q96PC5,Q9H2C2,Q9H2D1,Q8TB61,P57088,O15258,P13073,O95202,O95563,Q9GZM5,Q8N8Q8,Q9NZJ7,Q9NPA0,Q96AG4,Q9NW15,Q8NHH9,Q07065,P12235,P54105,Q8N4V1,Q9HD20,P24390,Q99805,Q9NQZ5,Q9Y5Y5,Q8IYU8,P16260,P16615,P12236,P54646,Q9Y619,Q8NFH5,O60831,Q9BSK2,Q9Y320,Q9Y696,Q9Y371,P56962,P50416,Q96HV5,Q9HBM0,Q9HC07,Q03518,Q6UW68,O43752,Q08722,Q96JJ7,O76024,O43681,A8CG34,P21912,Q9UH99,Q9BTX1,Q6NUK1,Q99643,O96008,Q9BXS4,Q9HC21,Q9UM00,Q9UI14,Q9BQT8,O43808,Q9Y512,Q9Y639,P56589,Q9H300,Q9UBU6,Q9BPX6,P20674,O75340,Q07812,Q9HCU5,Q9Y3C0,Q8IWA4,Q13438,O94901,Q8WTV0,Q9Y6C9,Q12846,O75381,Q6P4A7,Q9Y287,P30825,O75915,Q8TBA6,P05141,P50570,Q92973,Q9BUB7,Q9UBV2,P46977,P98194,O96005,P33897,Q8TEX9,Q9NR77,Q5T9L3,Q96NB2,Q92544,O14975,Q9Y276,Q9NPA8,P08183,P51572,O95433,P62942,P49755
Functions
Protein Atlas Protein class
protein_atlas_protein_class
513,5,6,521,10,532,526,539,32,547,38,42,47,50,53,54,57,61,62,65,68,71,75,80,83,84,87,94,96,97,98,99,104,105,110,112,124,129,132,139,140,142,144,151,154,153,158,160,161,162,164,167,170,174,175,176,179,185,186,188,196,200,210,216,218,217,214,213,219,220,221,228,240,249,255,258,262,261,264,266,275,285,290,302,300,309,310,316,315,313,317,323,324,331,333,335,342,349,347,354,358,366,364,362,359,373,377,372,370,378,391,383,393,397,403,410,411,412,413,417,429,425,426,440,443,447,457,455,460,477,480,484,485,489,503,511
657,2830,264,2391,2593,1427,62,941,3185,1529,1449,1692,2130,1161,782,460,2859,1003,110,1093,1762,2595,1800,1026,261,1954,249,2641,317,1727,521,2157,1981,83,1428,1111,943,1530,200,1351,96,347,2979,370,1801,3133,1955,575,760,57,393,1072,262,2099,359,979,1890,980,864,1201,124,1004,2751,2072,489,129,425,300,1598,1804,3040,1768,2752,2440,1402,921,1532,526,944,3023,403,2361,884,2159,638,2491,484,1631,1831,885,2043,1028,1930,3024,3099,158,185,2969,112,3124,2044,577,176,179,2420,680,1431,349,903,2851,2890,266,164,2134,1008,383,1700,1670,426,1776,614,2079,904,1702,1329,1080,1385,947,2284,587,3175,50,1990,1505,417,849,511,2804,2316,213,410,2757,1838,485,2167,798,2576,588,1031,617,1839,1100,160,186,629,1208,1082,1118,1605,331,214,105,84,1386,1435,2082,1144,2577,1480,1209,2679,3176,2650,1607,503,2343,788,2223,1640,2853,1413,2735,3212,429,703,2938,3156,869,228,1904,870,153,2143,354,255,2962,1083,1780,1643,372,672,362,2535,2369,1875,3095,1939,1338,2322,2940,42,1996,1239,75,2202,1707,705,1085,94,602,1463,545,1269,2117,1060,1013,684,2451,675,447,998,54,2057,2059,3186,290,735,378,1679,240,1392,47,818,3149,364,2856,1193,1150,175,837,161,80,1062,139,539,2954,3143,1366,676,196,154,2882,652,2838,2507,104,397,2742,1038,440,373,2480,5,1713,455,2432,2482,748,411,565,736,53,68,144,1126,1716,87,1040,219,258,912,1128,594,457,547,97,1820,1271,653,513,2035,963,302,2207,167,342,313,2484,1041,210,285,412,32,71,655,3011,935,309,1525,677,768,606,132,6,2122,98,99,1754,1043,1976,333,3116,65,38,1855,752,678,1223,220,221,310,358,162,142,480,170,443,1251,3160,2724,2383,3213,1276,916,151,1756,140,740,840,10,2462,1495,335,1344,413,61,2353,1022,275,1090,2212,315,2956,778,2547,2710,1757,316,2764,1091,477,391,216,217,532,366,1797,1559,323,2037,1690,174,188,324,218,377,977
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3,220
Mitochondria
140
425
4.780325
0.000002
Q5VT66,Q8N4H5,Q8WY22,O43615,Q9NZ45,Q9P0S2,O60313,P08574,O14949,Q9Y606,Q5XKP0,O75964,Q96A26,Q9NS69,Q99797,P62072,Q14318,O14925,Q9NWS8,Q7Z7H8,Q9H4I9,O60830,P82650,P35232,Q13505,Q15070,Q99757,Q9NX63,Q5T440,O00165,Q70HW3,P45880,Q3SXM5,Q9UBX3,Q99595,Q9Y277,P43304,Q9H3K2,Q9BUR5,Q14197,Q9Y241,Q8TB36,Q86Y39,Q8N442,Q8IXI1,Q9H4I3,P17858,P57105,Q96H78,Q9GZT3,O94826,Q9H2D1,Q16891,Q9Y6M9,P13073,Q9NX40,Q9Y2R0,O95202,Q9NUQ2,Q9Y255,Q9UDX5,O75208,O43292,Q8NBN7,Q8NI60,Q9NSE4,O95302,P12235,Q9NQZ5,P52789,Q8WWC4,Q8IYU8,P16260,Q56VL3,Q9NX47,P23786,P12236,Q53H12,Q9NPL8,P50416,Q07820,Q96IX5,Q8WUK0,Q8TAE8,P56378,P53701,Q9NVI7,Q7KZN9,Q96EY8,Q6UXV4,Q8NBM8,Q99623,P21912,Q9BXK5,Q9NX14,O75947,Q9H7Z7,Q6NUK1,Q7LGA3,Q86UT6,Q8WVI0,O96008,P56385,Q96EX1,Q9HC21,Q9Y512,Q96ER9,P22695,Q9H300,P24539,Q9BPX6,O95139,P13674,O75431,Q5T9A4,Q8IWA4,Q10713,Q9Y6C9,P09669,O14548,Q6P4A7,Q96FX7,Q9H9P8,Q8NE86,P05141,Q9BUB7,Q9Y3D9,Q8N183,O95831,Q7Z434,P40939,Q8N2F6,Q9Y394,Q9BW91,Q9HD33,Q96NB2,Q96CU9,Q9NPA8,O75306,O75323
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
517,4,5,520,9,10,521,522,13,533,16,17,20,21,540,26,536,29,549,34,38,37,544,543,41,42,556,557,554,552,47,50,60,61,64,66,578,69,71,590,74,593,77,592,591,82,584,84,87,607,598,99,602,625,112,121,122,124,125,126,127,128,137,141,143,155,157,158,170,171,172,175,176,180,183,182,185,204,208,213,222,223,226,241,237,243,247,251,252,250,256,260,266,283,286,288,293,290,295,296,301,300,306,308,310,323,325,329,333,330,342,338,345,348,355,364,361,377,371,369,378,407,408,406,403,412,414,419,416,431,427,435,436,449,459,457,465,480,483,508
2830,552,1071,1925,994,369,1625,796,29,13,1092,759,2187,137,918,520,1695,2641,1253,1562,521,1094,1663,1428,37,1351,2642,128,483,508,2464,348,1451,1136,1564,2041,3103,1112,687,288,17,1982,598,1181,338,1201,1956,1182,124,671,157,416,300,1957,847,1324,1769,1402,403,3214,1403,1830,1234,522,2101,1404,371,1864,2043,922,1987,1565,1074,3216,158,185,112,345,1474,2012,176,1006,584,886,1502,1204,266,1453,2310,2161,329,1774,2789,182,1568,330,1699,628,1836,2045,2442,3187,3109,1406,681,2756,1503,1733,3154,1700,785,1569,543,3042,730,1895,786,1168,1736,1989,427,1141,1571,2716,578,948,50,1456,1504,1808,2970,2314,2678,3162,1030,1287,2495,1704,213,1099,1479,661,1331,867,171,2758,1458,243,1081,731,1778,3043,1675,237,306,84,2082,26,3180,544,1608,906,2891,2602,2140,1744,732,1573,1169,703,2194,2141,2531,870,222,361,853,2110,1543,3199,1266,873,41,3136,1438,590,536,969,42,802,1940,620,1648,2289,1148,1909,1390,1268,1515,1578,602,60,674,1360,2987,1418,204,180,889,663,3063,1650,706,803,554,355,1311,517,16,1785,2372,854,2427,290,2060,1581,378,1786,1547,2740,250,1652,47,251,1881,2228,295,1969,431,707,34,1394,3088,296,2000,77,1192,364,591,2774,175,419,435,592,4,2091,1365,256,141,875,1972,2120,406,2719,143,241,593,792,1682,1882,226,959,301,1445,172,1063,5,1615,999,1244,1420,858,1849,20,2266,1123,1124,1486,465,989,2744,325,308,2034,1915,252,407,2296,694,87,911,2232,223,457,932,2567,3215,1154,914,962,933,2867,64,260,556,540,2408,342,2094,1549,1752,1396,412,71,449,1105,283,1042,2121,1422,2208,1295,750,2929,607,936,1591,99,3012,2746,938,333,69,82,38,3004,2945,293,1196,752,678,753,408,1343,310,1552,1720,459,2124,480,208,1950,808,3184,2097,170,643,1275,21,155,2688,1319,1594,125,739,809,247,1108,2153,549,1397,286,121,183,557,2461,2067,9,1044,1658,1131,1252,10,2545,2638,61,2274,127,1023,1424,1885,778,3067,1980,74,126,66,1689,122,2356,1795,860,436,898,1558,2519,414,695,1281,323,533,377,625,811,1798
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3,220
Organelle inner membrane
126
260
4.727545
0.000002
O43676,P14406,Q9H061,O43615,O60313,P08574,Q9P0S2,O14949,Q5XKP0,O75964,Q9BTV4,Q9Y584,P62072,O14925,Q9H1E5,Q7Z7H8,Q9H4I9,O60830,P35232,P82650,Q13505,Q15070,Q9NX63,Q70HW3,O75844,Q9UBX3,Q99595,P43304,O75746,P15954,Q9BUR5,Q9H3K2,Q14197,Q9Y241,Q8N442,Q86Y39,P22830,Q16891,Q9H2D1,Q9Y6M9,P03886,P13073,P00846,Q9UDW1,Q9Y2R0,O95202,Q9UDX5,Q8IXM6,O75208,O95563,O95674,Q8N8Q8,Q8NBN7,Q8NI60,Q9Y6N1,P12235,Q8WWC4,Q8IYU8,P16260,Q9Y5J9,P23786,P12236,Q9Y619,Q5SNT2,Q53H12,Q9NPL8,Q9BSK2,Q9UG56,Q96IX5,Q8WUK0,P56378,P53701,Q9NVI7,Q7KZN9,Q6UXV4,Q99623,P21912,Q9UH99,Q96AQ8,Q9NX14,O75947,Q6NUK1,Q99643,O96008,O75880,P56385,Q9HC21,Q9BQT8,Q9Y512,Q96ER9,P22695,Q9H300,P24539,Q9BYD1,Q9BPX6,O95139,Q9Y5J6,P20674,O75431,Q5T9A4,Q9BRJ2,Q10713,O94901,Q9Y6C9,Q9NVS2,P09669,O14548,Q6P4A7,O95167,Q9H9P8,Q8NE86,P05141,Q9BUB7,Q9Y3D9,Q9UJZ1,Q8N183,O95831,P40939,Q9HD33,Q96NB2,Q14739,Q96CU9,P50402,Q9Y276,O75306,Q567V2
Localization
GO Cellular component
msigdb_gocc
1,2,6,520,521,522,10,13,16,17,541,23,26,29,30,34,38,37,543,544,41,42,557,47,57,61,64,578,575,577,71,69,590,74,592,77,600,602,99,625,103,112,115,120,122,124,127,130,128,129,138,139,141,143,148,158,172,175,176,181,182,185,188,195,204,208,210,212,223,226,237,243,247,251,250,260,266,275,282,286,288,290,302,300,298,306,310,313,323,325,329,333,330,343,342,338,346,349,348,355,356,361,359,377,376,371,369,378,394,408,406,403,412,414,422,419,416,427,459,457,454,465,470,477,483,504
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Drugs and Diseases
Pharos IDG Category
pharos_protein_category
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3,220
Golgi apparatus
87
327
3.422045
0.000622
Q9NTJ5,Q15691,P80303,Q9Y3B3,O95197,P05023,Q9P2W9,Q8NCH0,Q8N4A0,Q5VW38,Q9Y282,O00400,Q8N2A8,Q96A57,Q9BUR5,O95249,Q5BJH7,Q02818,Q15012,Q8NBN3,O43731,Q16799,Q9H2C2,L0R6Q1,Q8TB61,O15258,O60499,Q9NX40,Q9GZM5,Q7Z3D4,Q7RTS9,O00461,Q8N4V1,P24390,Q99805,Q9H4A6,Q9NPR9,Q56VL3,P54646,Q96RQ1,O95070,Q92520,Q9Y371,Q9HC07,O14653,Q6NUQ4,Q10472,Q9NP72,Q96JB2,O43752,O14735,P61026,Q9H7Z7,Q9Y3E0,Q7LGA3,Q9BXS4,Q9UM00,Q9UI14,Q9NRB3,Q969X5,Q9Y3A6,Q10713,Q9C0D9,Q12846,Q9Y287,Q8NF37,Q8TBA6,O94830,P50570,Q9Y5Z9,P98194,O00203,O43505,Q9H0U4,P62820,Q5T9L3,Q9H3P7,Q92544,O75396,Q9NR31,Q9H8Y8,Q12893,P51572,Q8IV08,Q15392,P61019,P49755
Localization
GO Cellular component
msigdb_gocc
518,516,12,532,15,526,31,35,45,54,56,62,67,68,71,73,76,79,81,86,92,94,98,102,104,110,118,121,132,134,147,159,161,164,167,173,178,180,186,187,189,206,217,221,225,239,238,254,253,249,265,280,293,294,295,309,316,315,322,341,344,361,375,372,391,396,397,402,410,415,429,433,437,442,446,447,450,455,452,467,476,478,485,488,495,494,511
102,433,62,1529,2414,159,1693,2278,225,265,1596,3022,782,2489,1694,1003,110,1093,2187,1472,1230,437,1560,92,1954,249,3089,1561,699,612,118,1049,1428,2726,2714,1374,2786,452,3142,2596,2873,402,189,15,73,1004,1096,2524,1697,1429,865,1233,2440,526,3023,3031,2950,1300,1256,885,1113,646,1028,3099,1931,1893,2336,2337,1669,1431,2890,1204,1634,2468,164,1098,945,2980,1535,2312,1636,2014,1284,1807,614,601,1328,1408,718,2598,1739,1505,2255,1261,1933,511,1810,1961,771,410,2806,689,1838,1434,949,485,2081,772,798,2444,2877,1962,2937,2852,2733,186,1540,1868,2258,494,280,1993,2760,2650,3206,446,905,2083,12,2447,888,429,2938,2193,2023,79,1009,928,2474,238,1083,361,372,478,1542,690,907,672,3131,1965,2368,1034,1995,618,2925,1875,1359,1939,2226,1170,2963,2916,81,2940,950,2582,1239,1783,495,1941,516,2086,1085,94,1516,180,76,447,2605,54,953,239,1014,2606,765,623,631,3097,2965,295,147,2998,3149,134,971,632,2741,2374,2817,1216,1518,488,1484,1193,2062,67,563,1291,45,161,957,86,35,1972,1292,3143,1015,396,104,397,805,3192,3174,2821,960,2705,206,1883,856,455,1715,2608,565,2588,3065,341,961,68,2206,3132,253,1127,819,2823,1271,187,653,1821,2035,654,806,167,2297,934,2484,1524,1066,541,71,749,1550,1222,2237,309,1525,1156,3003,375,132,442,98,450,2722,173,293,476,1274,2328,3105,1342,221,254,178,1159,2637,467,322,1466,518,121,609,1130,2384,840,2128,31,1494,667,315,3193,1858,2547,2244,316,3128,1497,822,2764,993,685,2749,756,56,391,1279,2389,1557,217,1828,344,532,294,2277,415,3084,781,611
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3,220
Mitochondrial complex iv assembly
9
16
3.254162
0.001137
P14406,Q9P0S2,Q8N8Q8,Q9Y241,P13073,Q9Y6N1,Q7KZN9,Q9Y2R0,P20674
Processes and pathways
WikiPathways
msigdb_wp
2,10,139,74,112,148,251,122,349
994,1253,1598,371,2043,112,2,577,349,251,139,1396,10,74,122,148
0.22961279842123378,0.055331969068424594,-0.13536018457472698,1.0224874166341895,-0.3430078305713249,2.0380155210262614,4.3291217026971225,0.6442470592213966,1.0917521341398324,1.4073803914068117,1.8920646818638314,-0.01777473199075143,4.3291217026971225,2.52203320891506,1.9850548401175079,1.8387488109229877
3,220
Mitochondrial calcium ion transport
12
18
3.224508
0.001262
Q9Y277,Q99623,Q9H4I9,P21796,Q10713,Q8WWC4,Q9H300,Q8IYU8,P45880,Q8NE86,Q9BPX6,O95202
Processes and pathways
Reactome Pathways
msigdb_reactome
66,260,38,70,361,172,333,175,50,406,342,124
1451,124,70,543,50,361,175,406,172,1244,962,260,342,333,38,422,66,1281
-0.06177987491864927,1.9717947009390235,2.5995589664368004,0.7007425622241883,2.907101064760008,1.06407470918364,1.6914484940680552,0.9669038074280564,1.704881209746608,0.06991835486739327,0.27292895481255514,1.3801250919931503,1.1193918429266982,1.1331976156562682,3.2106974716483787,0.9390541618071563,2.6382243688422604,0.055331969068424594
3,220
Tetrapyrrole binding
12
19
3.138072
0.001701
O43169,O00264,Q7KZN9,Q9H7Z7,Q6UW02,Q9NRV9,O15173,P53701,Q16850,P30519,P09601,Q96EY8
Functions
GO Molecular function
msigdb_gomf
0,88,251,293,230,205,11,243,215,24,152,252
88,11,0,525,522,152,1453,24,243,215,230,251,2839,2508,252,302,1293,293,205
2.2747847087222794,4.293019093243848,4.3291217026971225,0.7289291660118463,0.7430072800978298,1.8120416545482296,-0.06177987491864927,3.4981163078685293,1.420994700450676,1.5160479135785023,1.4617845329488237,1.4073803914068117,-0.8271293488640873,-0.5833609844142108,1.4073803914068117,1.2433090578397443,0.04073397966432928,1.2844490111299678,1.5566539160615283
3,220
Cytochrome complex assembly
7
14
3.124471
0.001781
Q9P0S2,Q15070,Q8N8Q8,Q9BSK2,P53701,Q7KZN9,Q9Y2R0
Processes and pathways
GO Biological process
msigdb_gobp
10,42,139,210,243,251,122
1253,298,243,42,1419,854,251,139,1752,1396,210,10,477,122
0.055331969068424594,1.2433090578397443,1.420994700450676,3.0972988744230174,-0.03243127960906722,0.344901195162577,1.4073803914068117,1.8920646818638314,-0.19444171825613035,-0.01777473199075143,1.5295919290991515,4.3291217026971225,0.8412731718875827,1.9850548401175079
3,220
Intracellular protein transport
88
328
3.100624
0.001931
Q99442,P43307,Q8N4H5,O43615,Q9Y3B3,P61009,P31751,Q9NS69,Q9Y584,Q99797,P62072,O14925,Q9P2W9,Q9BUN8,Q96P70,Q53FT3,O60830,Q9Y5X3,Q15070,O00165,P40763,Q5HYI8,Q9Y282,P46379,Q99595,O60725,Q15629,Q8TB36,Q5BJH7,P40855,P57105,Q9Y6Y8,Q9H9H4,O94826,Q15005,Q15388,O75298,O60499,Q8N8Q8,Q9BRK0,Q8WWC4,Q9Y5Y5,Q9Y5J9,Q969Q5,Q8NFH5,P30536,Q53H12,Q9Y5M8,Q9Y371,P56962,Q15041,Q9NP72,Q96JB2,O43752,Q99623,O43681,A8CG34,Q7Z4Q2,O96008,Q9Y512,P56589,Q9H300,Q9Y3A6,Q9Y5J6,O75340,Q07812,Q9HCU5,Q10713,Q13438,Q12846,O75381,Q92973,Q9UBV2,Q9Y679,O95831,P55786,Q7Z434,O00203,Q8TEX9,Q9H0U4,P62820,Q5T9L3,Q92544,Q9NR31,P50402,Q9Y276,P51572,P49755
Processes and pathways
GO Biological process
msigdb_gobp
513,3,4,520,532,528,527,21,23,540,26,29,31,32,547,546,37,559,42,552,553,55,56,579,64,72,75,593,76,587,84,611,608,598,106,620,108,118,139,145,172,174,181,191,196,197,204,209,217,214,244,254,253,249,260,261,264,291,300,323,331,333,344,346,347,354,358,361,362,372,370,411,413,423,416,428,431,433,440,442,446,447,455,467,470,477,485,511
264,2391,552,2521,433,941,1449,1692,2278,670,29,942,2859,1694,1093,1762,1109,2595,918,1026,520,261,1954,249,1163,1727,118,1231,1111,72,1563,2714,37,108,1399,347,370,1801,1451,1955,2099,598,1890,980,1891,1201,2072,2767,1984,3134,1803,416,300,2073,1402,3205,944,884,1958,1325,1831,1183,885,1633,1987,1929,2969,3124,1076,3147,3041,761,1669,1865,728,1431,2890,2134,1078,2077,2980,1258,2935,197,2014,527,984,1670,2135,1807,2079,1702,1329,1736,718,553,587,3,1990,579,1505,2255,849,511,2804,2316,1810,1478,850,470,771,1898,1838,485,798,2576,1031,2877,1962,2937,2852,1839,2341,1236,1082,1605,428,331,214,84,1386,1435,1868,2258,528,1144,800,1993,1209,2760,2650,851,1935,26,852,3206,446,1607,1814,2600,2343,788,831,2447,888,2938,1145,1642,1058,354,2907,1083,361,372,907,1574,908,672,2624,362,2368,618,1875,1647,1438,1359,1338,3126,106,2940,244,42,1102,1441,1239,620,1941,75,2656,1784,1648,1707,2738,705,674,546,204,76,55,1650,2451,447,1999,2324,3196,818,2405,431,291,2741,1216,3173,1484,837,4,139,196,2838,2507,593,693,440,1914,2480,2821,172,2705,455,725,3071,2482,748,411,2608,191,1521,1125,1126,253,1128,547,2269,1820,1271,513,2326,2035,963,2509,64,260,3037,540,1919,145,32,749,3011,935,1550,1525,936,442,937,2351,333,3013,3112,2763,2747,2210,1274,608,1342,1223,1343,358,254,467,1466,21,2383,2271,1252,2869,31,1371,1494,1495,413,1022,1090,667,2956,1424,2516,2547,1069,1757,1555,3128,2387,964,1497,965,477,56,2389,217,2812,344,532,1922,2129,323,23,346,181,2413,209,2277,1024,559,174,3084,423,781,611
1.3528340672655668,-0.5229597504510352,0.6866340160886069,-0.5984945173388617,0.9111656785685303,0.27292895481255514,-0.06177987491864927,-0.1796530741697238,-0.46276900728826853,0.5307604103957996,3.361075633693647,0.27292895481255514,-0.8578500553259483,-0.1796530741697238,0.15719497235672153,-0.20924260096857328,0.14267746792433023,-0.6439755827313389,0.28734545070934525,0.20067947103783892,0.7430072800978298,1.3664840566092424,-0.29830712100880136,1.4073803914068117,0.11360824532721736,-0.19444171825613035,2.0115511185478705,0.06991835486739327,0.14267746792433023,2.5349723241443067,-0.1206201069740683,-0.7200483638187551,3.2106974716483787,2.0512358149832477,-0.03243127960906722,1.0917521341398324,1.0224874166341895,-0.2240557615419202,-0.06177987491864927,-0.29830712100880136,-0.37287144055437577,0.6159377018946759,-0.2685693060796182,0.24406266179274372,-0.2685693060796182,0.08449317262514162,-0.35793329427295245,-0.7658567140592568,-0.313194785097642,-1.4847663908172626,-0.2240557615419202,0.9390541618071563,1.2433090578397443,-0.35793329427295245,-0.03243127960906722,-3.453474195688348,0.27292895481255514,0.3161453056172049,-0.29830712100880136,0.011503046829603012,-0.23888123943057013,0.09905645771621088,0.3161453056172049,-0.15011234602282414,-0.313194785097642,-0.28343197486238475,-0.996802007858918,-1.4209510204632576,0.1717011182043829,-1.6778148675872004,-1.1369422393917046,0.43090764101721113,-0.164876629692285,-0.2537190743102173,0.4594902255077705,-0.04709964827475354,-0.8886275567160946,-0.387822311164995,0.1717011182043829,-0.35793329427295245,-1.0123137479236077,0.055331969068424594,-0.9503545811838279,1.570171930412102,-0.3280950079380358,0.7289291660118463,0.24406266179274372,-0.164876629692285,-0.387822311164995,-0.2240557615419202,-0.35793329427295245,-0.1796530741697238,0.011503046829603012,-0.19444171825613035,0.473765489840932,0.6866340160886069,0.6300975384411448,4.3291217026971225,-0.313194785097642,0.6442470592213966,-0.09117605087284349,-0.447753880325114,0.344901195162577,0.7711332727194923,-0.796465034426316,-0.47779711418441184,-0.2240557615419202,-0.07647199667296625,0.344901195162577,0.8412731718875827,0.4166002588713612,-0.2685693060796182,-0.23888123943057013,0.8132470889449575,0.38795315862879387,-0.6288017705240093,0.20067947103783892,-0.873231681277683,-0.29830712100880136,-0.9503545811838279,-0.842482628027553,-0.23888123943057013,-0.4928382444842881,0.06991835486739327,0.1717011182043829,-0.13536018457472698,0.9251147879781412,1.1331976156562682,1.5160479135785023,2.3661898889393695,-0.01777473199075143,-0.04709964827475354,-0.2537190743102173,-0.447753880325114,0.7289291660118463,0.12814857045825676,0.38795315862879387,-0.313194785097642,0.08449317262514162,-0.7505734286242784,-0.674363810312437,0.344901195162577,-0.28343197486238475,3.448371427949981,0.344901195162577,-3.527645662378537,0.8832381475623974,-0.13536018457472698,-0.2240557615419202,-0.6439755827313389,-0.4928382444842881,0.4022821085379622,0.35926273373079604,-0.553133878075549,0.3161453056172049,-0.9503545811838279,0.12814857045825676,-0.15011234602282414,0.1861959397352981,1.0779181486196767,-0.9040377327922564,0.1717011182043829,1.06407470918364,1.0224874166341895,0.3017508900780304,-0.1206201069740683,0.3017508900780304,0.5307604103957996,-0.6591629137722387,1.06407470918364,-0.5078924419127835,0.6017675204564823,-0.2537190743102173,-0.15011234602282414,-0.04709964827475354,-0.003129968688779517,0.011503046829603012,-1.4209510204632576,2.0644481952430347,-0.9503545811838279,1.420994700450676,3.0972988744230174,0.15719497235672153,-0.04709964827475354,0.06991835486739327,0.6017675204564823,-0.28343197486238475,2.4831720044145342,-0.674363810312437,-0.20924260096857328,-0.15011234602282414,-0.1796530741697238,-0.7353039946740639,0.4880301099656987,0.5307604103957996,0.7007425622241883,1.5566539160615283,2.431254128827567,2.766646055942991,-0.15011234602282414,-0.553133878075549,0.8832381475623974,-0.313194785097642,-0.47779711418441184,-2.9289291132688615,0.37361337759597135,-0.5229597504510352,0.9251147879781412,1.2844490111299678,-0.7353039946740639,0.08449317262514162,-1.9226522752457913,-0.07647199667296625,0.35926273373079604,4.3291217026971225,1.8920646818638314,1.5836813204612712,-0.8271293488640873,-0.5833609844142108,0.6300975384411448,0.5022841164890406,0.8972068072481052,-0.2685693060796182,-0.5682407864248026,-0.8117901676292918,1.704881209746608,-0.7048064879620904,0.8692596729318535,0.473765489840932,-1.183926602387414,-0.5682407864248026,0.4452042862052327,0.9529838262623884,-0.6439755827313389,1.6106743124643152,-0.09117605087284349,0.14267746792433023,0.14267746792433023,1.4073803914068117,0.14267746792433023,0.7007425622241883,-0.447753880325114,-0.2240557615419202,0.055331969068424594,0.7711332727194923,-0.47779711418441184,-0.3280950079380358,0.27292895481255514,-0.5833609844142108,2.663965486017274,1.3801250919931503,-1.1213111905822806,0.7148409361035052,-0.2685693060796182,1.8520900546502441,3.3235678990202806,0.4452042862052327,-1.0745084676736767,0.28734545070934525,-0.1058920750579502,-0.09117605087284349,0.28734545070934525,0.8972068072481052,0.28734545070934525,-0.4928382444842881,1.1331976156562682,-1.0745084676736767,-1.357395678717921,-0.7505734286242784,-0.7353039946740639,-0.4177623935728443,0.055331969068424594,0.6159377018946759,0.011503046829603012,0.08449317262514162,0.011503046829603012,1.0779181486196767,1.4073803914068117,0.8552713566510017,-0.06177987491864927,3.5973077301556384,-0.5078924419127835,-0.447753880325114,0.06991835486739327,-0.8578500553259483,3.3485794389162113,-0.003129968688779517,-0.07647199667296625,-0.07647199667296625,0.9529838262623884,0.2151517460221033,0.1717011182043829,0.544982758232892,-0.9658224777764525,-0.03243127960906722,-0.5833609844142108,-0.5984945173388617,0.1861959397352981,-0.19444171825613035,-0.1058920750579502,-1.4368803248197939,-0.5078924419127835,0.27292895481255514,-0.07647199667296625,0.27292895481255514,0.8412731718875827,2.753835667498494,-0.5078924419127835,1.5160479135785023,-0.796465034426316,1.1193918429266982,0.7289291660118463,-0.2685693060796182,-0.37287144055437577,1.174558901603863,3.5725469272262074,1.1055766906461557,1.6510996458924831,-0.5229597504510352,1.5431272560932738,-0.447753880325114,0.2151517460221033,0.6866340160886069,1.704881209746608,-1.2310489994219513,0.9390541618071563,0.4166002588713612,0.6159377018946759
3,220
Endoplasmic reticulum tubular network organization
9
14
3.093897
0.001975
P57088,O95197,Q9BRK0,Q9NQC3,P61026,Q15041,Q6NUK4,Q8NHH9,Q9NP72
Processes and pathways
GO Biological process
msigdb_gobp
105,15,145,117,280,244,281,154,254
15,105,280,244,950,2059,281,154,145,768,2351,334,254,117
3.868076986161342,2.0644481952430347,1.3118301474062795,1.420994700450676,0.27292895481255514,-0.3430078305713249,1.3118301474062795,1.8120416545482296,1.8520900546502441,0.43090764101721113,-0.4928382444842881,1.1331976156562682,1.4073803914068117,2.0247872950224237
3,220
Protein transporter activity
9
16
3.088426
0.002012
Q99595,Q9HD20,O60830,O96008,Q9Y5J9,Q9NS69,Q9Y584,O14925,Q07820
Functions
GO Molecular function
msigdb_gomf
64,162,37,300,181,21,23,29,222
29,37,598,300,511,1209,222,620,875,64,162,21,1022,23,346,181
3.361075633693647,3.2106974716483787,0.6159377018946759,1.2433090578397443,0.7711332727194923,0.08449317262514162,1.4889337304892023,0.6017675204564823,0.330528729857457,2.663965486017274,1.7719189526049448,3.5973077301556384,0.2151517460221033,3.5725469272262074,1.1055766906461557,1.6510996458924831
3,220
Endoplasmic reticulum tubular network
9
15
3.064283
0.002182
Q9H2C2,Q9H6H4,Q9BRK0,Q9NQC3,P61026,Q6NUK4,Q8NHH9,Q9NP72,Q00765
Localization
GO Cellular component
msigdb_gocc
98,334,145,117,280,281,154,254,59
470,280,59,1643,1338,950,2059,281,154,145,768,98,334,254,117
0.8412731718875827,1.3118301474062795,2.728193808841541,-0.15011234602282414,0.011503046829603012,0.27292895481255514,-0.3430078305713249,1.3118301474062795,1.8120416545482296,1.8520900546502441,0.43090764101721113,2.143557307496829,1.1331976156562682,1.4073803914068117,2.0247872950224237
3,220
Outer mitochondrial membrane protein complex
13
17
2.978801
0.002894
O75431,O94826,Q9Y512,Q8N4H5,Q16891,Q9BUR5,Q13505,Q8IWA4,Q9NX63,O96008,Q5XKP0,Q9NS69,Q6UXV4
Localization
GO Cellular component
msigdb_gocc
348,598,323,4,602,71,41,364,557,300,16,21,250
348,598,300,1736,41,620,602,889,16,250,364,4,71,21,809,557,323
1.0917521341398324,0.6159377018946759,1.2433090578397443,-0.19444171825613035,3.1099250993926355,0.6017675204564823,0.6159377018946759,0.3161453056172049,3.7822378308851308,1.4073803914068117,1.06407470918364,4.3291217026971225,2.5995589664368004,3.5973077301556384,0.38795315862879387,0.6866340160886069,1.174558901603863
3,220
Mitochondrial calcium ion transmembrane transport
8
11
2.940053
0.003282
Q9H4I9,P21796,Q8WWC4,Q8IYU8,Q8NE86,Q9BPX6,Q96AQ8,O95202
Processes and pathways
GO Biological process
msigdb_gobp
38,70,172,175,406,342,282,124
1451,124,70,175,406,172,282,342,38,422,1281
-0.06177987491864927,1.9717947009390235,2.5995589664368004,1.6914484940680552,0.9669038074280564,1.704881209746608,1.3118301474062795,1.1193918429266982,3.2106974716483787,0.9390541618071563,0.055331969068424594
3,220
Cytochrome complex
11
17
2.935812
0.003327
P14406,P22695,P08574,O14949,P13073,P09669,Q7KZN9,O14548,Q9UDW1,Q9Y276,P20674
Localization
GO Cellular component
msigdb_gocc
2,329,522,13,112,371,251,369,120,477,349
994,369,13,1598,522,371,2043,112,2,1326,577,349,329,785,251,120,477
0.22961279842123378,1.0224874166341895,4.196501680534049,-0.13536018457472698,0.7430072800978298,1.0224874166341895,-0.3430078305713249,2.0380155210262614,4.3291217026971225,0.011503046829603012,0.6442470592213966,1.0917521341398324,1.1331976156562682,0.4022821085379622,1.4073803914068117,2.0115511185478705,0.8412731718875827
3,220
Cristae formation
10
21
2.914154
0.003567
O75947,Q9Y512,Q9BUR5,Q13505,Q5XKP0,O75964,P56385,P24539,P00846,Q6UXV4
Processes and pathways
Reactome Pathways
msigdb_reactome
288,323,71,41,16,17,306,330,115,250
348,288,17,115,1403,1006,330,1836,985,1736,1808,1675,306,41,602,16,250,71,809,557,323
1.0917521341398324,1.2844490111299678,3.7453603850636794,2.0247872950224237,-0.03243127960906722,0.2151517460221033,1.1331976156562682,-0.23888123943057013,0.24406266179274372,-0.19444171825613035,-0.2240557615419202,-0.164876629692285,1.2295774465746885,3.1099250993926355,0.6159377018946759,3.7822378308851308,1.4073803914068117,2.5995589664368004,0.38795315862879387,0.6866340160886069,1.174558901603863
3,220
Calcium ion import
8
13
2.91197
0.003592
Q9H4I9,P21796,Q8WWC4,Q8IYU8,Q9BPX6,P16615,Q96AQ8,O75844
Processes and pathways
GO Biological process
msigdb_gobp
38,70,172,175,342,179,282,57
1350,57,179,70,2981,175,406,172,282,342,38,1593,1281
-0.003129968688779517,2.7410182567646277,1.6510996458924831,2.5995589664368004,-1.0123137479236077,1.6914484940680552,0.9669038074280564,1.704881209746608,1.3118301474062795,1.1193918429266982,3.2106974716483787,-0.1206201069740683,0.055331969068424594
3,220
Inner mitochondrial membrane organization
13
24
2.907899
0.003639
Q9Y512,Q9H3K2,Q9BUR5,Q13505,Q53H12,Q8WWC4,Q9Y5J6,Q5XKP0,Q9Y5J9,Q9Y584,P62072,O95202,Q6UXV4
Processes and pathways
GO Biological process
msigdb_gobp
323,69,71,41,204,172,346,16,181,23,26,124,250
521,348,598,124,1006,1736,26,41,602,204,889,16,250,172,71,69,809,557,1252,1281,323,23,346,181
0.7430072800978298,1.0917521341398324,0.6159377018946759,1.9717947009390235,0.2151517460221033,-0.19444171825613035,3.448371427949981,3.1099250993926355,0.6159377018946759,1.5566539160615283,0.3161453056172049,3.7822378308851308,1.4073803914068117,1.704881209746608,2.5995589664368004,2.62534308033295,0.38795315862879387,0.6866340160886069,0.06991835486739327,0.055331969068424594,1.174558901603863,3.5725469272262074,1.1055766906461557,1.6510996458924831
3,220
Mitochondrial nucleotide transporter subfamily
9
10
2.890452
0.003847
Q9H2D1,Q6NUK1,Q70HW3,P16260,Q9BSK2,Q9HC21,P12236,O43808,P12235
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
99,290,47,176,210,310,185,317,158
317,403,158,185,176,290,47,210,99,310
1.1883274006382527,0.9669038074280564,1.7853014752695062,1.6241579565962334,1.6780073418899184,1.2844490111299678,2.9706691886854455,1.5295919290991515,2.143557307496829,1.215836649167216
3,220
Proton transporting atp synthase complex
6
12
2.87974
0.00398
O75947,P56378,O75964,P56385,P00846,Q96IX5
Localization
GO Cellular component
msigdb_gocc
288,237,17,306,115,223
288,17,115,1403,330,1836,985,1808,1675,237,306,223
1.2844490111299678,3.7453603850636794,2.0247872950224237,-0.03243127960906722,1.1331976156562682,-0.23888123943057013,0.24406266179274372,-0.2240557615419202,-0.164876629692285,1.4346001455642394,1.2295774465746885,1.4889337304892023
3,220
Intrinsic component of golgi membrane
12
14
2.878021
0.004002
Q9NRB3,L0R6Q1,Q8TB61,P98194,Q5BJH7,O15258,Q969X5,Q8N2H4,Q9Y282,O43505,O95070,Q9Y5Z9
Localization
GO Cellular component
msigdb_gocc
322,102,104,429,76,110,341,563,56,437,189,415
102,110,437,189,429,2474,76,631,563,104,341,322,56,415
2.090849287701112,2.0380155210262614,0.8972068072481052,1.6106743124643152,0.9251147879781412,-0.5682407864248026,2.431254128827567,0.5875869648575647,0.6725152692738572,2.090849287701112,1.1193918429266982,1.174558901603863,2.753835667498494,0.9529838262623884
3,220
Intrinsic component of mitochondrial inner membrane
25
38
2.876199
0.004025
O95563,Q9P0S2,Q8N8Q8,Q5XKP0,Q9H9P8,Q9Y6N1,Q96AQ8,O14925,Q9H4I9,O60830,Q13505,Q15070,O75880,Q9HC21,Q99595,Q9Y512,Q96ER9,Q9H3K2,Q9BUR5,Q53H12,Q9UG56,O75431,Q6P4A7,Q9Y2R0,Q6UXV4
Localization
GO Cellular component
msigdb_gocc
129,10,139,16,408,148,282,29,38,37,41,42,298,310,64,323,325,69,71,204,212,348,378,122,250
29,1253,37,348,298,129,1006,1736,703,41,42,1514,602,204,889,16,378,250,139,406,282,325,457,64,71,69,38,678,408,310,809,557,10,212,122,1281,323,148
3.361075633693647,0.055331969068424594,3.2106974716483787,1.0917521341398324,1.2433090578397443,1.9452503290298178,0.2151517460221033,-0.19444171825613035,0.4880301099656987,3.1099250993926355,3.0972988744230174,-0.09117605087284349,0.6159377018946759,1.5566539160615283,0.3161453056172049,3.7822378308851308,1.0086059102080356,1.4073803914068117,1.8920646818638314,0.9669038074280564,1.3118301474062795,1.160781120599868,0.8692596729318535,2.663965486017274,2.5995589664368004,2.62534308033295,3.2106974716483787,0.5307604103957996,0.9669038074280564,1.215836649167216,0.38795315862879387,0.6866340160886069,4.3291217026971225,1.5295919290991515,1.9850548401175079,0.055331969068424594,1.174558901603863,1.8387488109229877
3,220
Processing of smdt1
9
13
2.873011
0.004066
Q9UJZ1,Q99623,Q9H4I9,Q10713,Q9H300,Q8WWC4,Q8IYU8,Q8NE86,Q9BPX6
Processes and pathways
Reactome Pathways
msigdb_reactome
422,260,38,361,333,172,175,406,342
1451,543,361,175,406,172,962,260,342,333,38,422,1281
-0.06177987491864927,0.7007425622241883,1.06407470918364,1.6914484940680552,0.9669038074280564,1.704881209746608,0.27292895481255514,1.3801250919931503,1.1193918429266982,1.1331976156562682,3.2106974716483787,0.9390541618071563,0.055331969068424594
3,220
Lipid metabolic process
113
297
2.823095
0.004756
Q9NTJ5,Q9H6K4,O15269,P31751,Q86YN1,P05023,O75881,Q2TAA5,Q9UKU0,Q9HBH5,Q15067,Q9BQE5,Q9BT22,P51648,P09960,Q96AD5,P21964,O75844,Q6PIU2,Q8NCC3,Q8N2A8,Q96N66,P33121,Q9NX62,Q9H2C2,P09455,Q6P1A2,Q8N9F7,P11802,Q9NUQ2,Q6Y1H2,P49356,P07602,O95749,Q9NPH0,O95470,Q9HBU6,O43292,O95674,Q9NZJ7,P11413,O00767,Q8NBN7,Q9UHD1,Q96G23,O75608,Q9BZF1,Q5T8D3,Q99805,P46109,Q15800,P50897,P23786,P54646,Q9NTX5,Q9NP80,O15254,P30536,Q2T9J0,Q53H12,Q9UG56,Q16850,P50416,Q8WUK0,Q9Y2B2,Q14534,P14174,Q99623,Q9BVG9,O43681,O14735,P16435,P38435,P35610,O15120,P14324,P00387,O14880,Q9H490,Q9H7Z7,O43808,Q92604,Q8NCG7,O75340,O15228,Q07812,Q10713,Q06136,Q86SQ9,Q8WTV0,Q9C0D9,Q8IXJ6,Q9P035,Q8NF37,Q9BV10,O94830,Q9UBV2,Q9UJZ1,P40939,Q53GQ0,P33897,Q6NUM9,Q9Y394,Q99943,Q92643,Q9H3P7,Q14739,P28161,O14975,Q15392,Q99735,Q9C0I1,Q8NBX0
Processes and pathways
GO Biological process
msigdb_gobp
518,7,519,527,19,526,525,538,25,542,537,33,39,44,561,566,51,57,571,581,67,594,585,609,98,111,113,633,627,125,641,639,638,637,131,133,136,137,138,140,647,644,141,667,150,658,677,675,167,682,177,689,182,186,713,712,192,197,198,204,212,215,213,226,233,229,235,260,263,261,265,269,270,271,276,278,284,287,292,293,317,340,350,347,353,354,361,360,367,373,375,379,382,396,398,402,413,422,427,430,426,434,436,441,448,450,454,461,460,495,499,507,506
757,1469,697,966,2414,3208,644,1625,796,265,3022,287,460,1003,276,353,192,519,758,759,137,918,1230,261,317,1094,2188,883,3120,347,3030,3133,1564,2873,658,57,1376,1862,525,402,979,1096,133,1697,138,637,2787,1202,901,865,284,1233,2308,2752,526,3023,3214,2280,3031,1403,2921,1501,638,3179,1300,1139,111,561,1074,647,3216,1005,627,1474,235,278,2621,1114,1931,3139,1893,269,2336,3107,1731,51,1634,827,2161,182,1699,1836,2045,946,461,1008,2527,1503,1382,197,527,828,585,426,1304,271,2422,2136,3100,1168,270,3210,427,1141,2598,866,2716,1602,1456,925,682,3018,1740,1261,1933,639,1287,213,771,689,1838,2732,44,1305,2400,1899,1100,1288,186,1778,3002,1868,3176,2770,1573,2497,3156,3044,2193,1265,1145,2814,1058,360,354,361,3199,3217,2534,1966,2807,229,454,1609,2940,537,1440,1967,802,1308,834,1010,495,3008,2656,1907,177,1514,2738,1085,1268,1515,215,198,1086,538,2987,430,204,675,2172,954,434,113,735,571,641,804,1817,2965,367,1442,2147,19,1192,379,1653,67,2479,3137,3167,633,141,747,506,581,350,396,3130,958,838,373,226,1655,340,448,1420,748,2901,566,1103,3098,150,594,1129,710,1821,2509,260,1369,499,167,892,441,33,39,1066,398,3219,263,1294,1105,1042,1067,677,375,507,98,975,450,292,2796,7,293,1196,3072,542,136,712,131,1592,1447,1593,518,713,125,916,609,1130,769,140,382,840,1722,413,212,2948,667,1496,1023,2516,422,25,2691,842,233,436
0.43090764101721113,-0.07647199667296625,0.4880301099656987,0.25850136951980746,-0.5380402143385864,-4.45856096536647,0.5591946133780552,-0.15011234602282414,0.38795315862879387,1.3528340672655668,-1.1056952498169008,1.2844490111299678,0.8552713566510017,0.2151517460221033,1.3118301474062795,1.0779181486196767,1.5971821074339623,0.7430072800978298,0.43090764101721113,0.43090764101721113,1.8920646818638314,0.28734545070934525,0.06991835486739327,1.3664840566092424,1.1883274006382527,0.15719497235672153,-0.4177623935728443,0.3161453056172049,-1.4050379673443167,1.0917521341398324,-1.1213111905822806,-1.4847663908172626,-0.1206201069740683,-0.873231681277683,0.544982758232892,2.7410182567646277,-0.01777473199075143,-0.2537190743102173,0.7289291660118463,0.9669038074280564,0.24406266179274372,0.15719497235672153,1.9186737066568227,-0.1796530741697238,1.8920646818638314,0.5733960056844266,-0.7811538996650151,0.08449317262514162,0.3017508900780304,0.330528729857457,1.298144113646831,0.06991835486739327,-0.47779711418441184,-0.7505734286242784,0.7289291660118463,-1.1056952498169008,-5.717795917786121,-0.46276900728826853,-1.1213111905822806,-0.03243127960906722,-0.934901193067858,-0.09117605087284349,0.5733960056844266,-2.071533493089385,0.02612435090038817,0.12814857045825676,2.0380155210262614,0.6725152692738572,0.1717011182043829,0.5591946133780552,-6.077994225893071,0.2151517460221033,0.5875869648575647,-0.07647199667296625,1.4346001455642394,1.3118301474062795,-0.6591629137722387,0.14267746792433023,-0.28343197486238475,-1.5488459500617,-0.2685693060796182,1.3391751012056732,-0.4928382444842881,-1.3415469960175879,-0.19444171825613035,2.843361746050272,-0.15011234602282414,0.35926273373079604,-0.4027859480941016,1.6376330607839327,-0.1796530741697238,-0.23888123943057013,-0.3430078305713249,0.27292895481255514,0.8552713566510017,0.2151517460221033,-0.5984945173388617,-0.09117605087284349,-0.01777473199075143,1.570171930412102,0.7289291660118463,0.35926273373079604,0.6300975384411448,0.9251147879781412,0.02612435090038817,1.3255071355722057,-0.5380402143385864,-0.387822311164995,-1.3098973772296592,0.11360824532721736,1.3391751012056732,-4.830640801337953,0.9251147879781412,0.12814857045825676,-0.6439755827313389,0.330528729857457,-0.7200483638187551,-0.13536018457472698,-0.06177987491864927,0.28734545070934525,0.5165275398650023,-1.0900943608184126,-0.19444171825613035,0.055331969068424594,-0.28343197486238475,0.5733960056844266,0.04073397966432928,1.5160479135785023,0.4166002588713612,0.5022841164890406,-0.23888123943057013,-0.7353039946740639,3.059380306475877,0.02612435090038817,-0.5229597504510352,-0.2685693060796182,0.15719497235672153,0.04073397966432928,1.6241579565962334,-0.20924260096857328,-1.0589375148302198,-0.2537190743102173,-1.9886334261219616,-0.7658567140592568,-0.1206201069740683,-0.5833609844142108,-1.7589816090395616,-1.1369422393917046,-0.4177623935728443,0.055331969068424594,0.12814857045825676,-0.8117901676292918,0.1861959397352981,1.06407470918364,1.0779181486196767,1.06407470918364,-3.197449390350844,-6.1771682271863915,-0.5984945173388617,-0.29830712100880136,-0.796465034426316,1.4617845329488237,0.8692596729318535,-0.13536018457472698,-0.9503545811838279,0.7148409361035052,-0.04709964827475354,-0.29830712100880136,0.38795315862879387,0.02612435090038817,0.35926273373079604,0.2151517460221033,0.7992191364595662,-1.0745084676736767,-0.674363810312437,-0.2685693060796182,1.6780073418899184,-0.09117605087284349,-0.7353039946740639,0.1717011182043829,0.055331969068424594,-0.09117605087284349,1.5160479135785023,1.570171930412102,0.1717011182043829,0.7148409361035052,-1.0278402096207813,0.9251147879781412,1.5566539160615283,0.5307604103957996,-0.4027859480941016,0.27292895481255514,0.9111656785685303,2.0380155210262614,0.4594902255077705,0.6583862932184593,0.5733960056844266,0.38795315862879387,-0.2240557615419202,-0.9813049356287264,1.0502217908149432,-0.04709964827475354,-0.387822311164995,3.5973077301556384,0.09905645771621088,1.0086059102080356,-0.15011234602282414,2.62534308033295,-0.5682407864248026,-1.5007613478674728,-1.8405909202008888,0.5875869648575647,1.8654231014435778,0.4452042862052327,0.7851812068774792,0.6442470592213966,1.0917521341398324,0.9808141312665962,-1.4528259447413778,0.27292895481255514,0.35926273373079604,1.0224874166341895,1.4753635194517039,-0.15011234602282414,1.1193918429266982,0.8832381475623974,-0.03243127960906722,0.4452042862052327,-0.8886275567160946,0.6725152692738572,0.15719497235672153,-1.2940963180601806,1.8253993507524382,0.6300975384411448,0.14267746792433023,0.4880301099656987,-0.2240557615419202,-0.5833609844142108,1.3801250919931503,-0.003129968688779517,0.7992191364595662,1.7317214132284093,0.3161453056172049,0.8972068072481052,3.31105252865081,3.198123884412577,0.1861959397352981,0.9808141312665962,-6.456585704094945,1.3664840566092424,0.04073397966432928,0.15719497235672153,0.20067947103783892,0.1861959397352981,0.5307604103957996,1.0224874166341895,0.7851812068774792,2.143557307496829,0.25850136951980746,0.8832381475623974,1.2844490111299678,-0.7811538996650151,4.3291217026971225,1.2844490111299678,0.09905645771621088,-1.183926602387414,0.7148409361035052,1.9053732541087869,0.4880301099656987,1.9452503290298178,-0.1206201069740683,-0.04709964827475354,-0.1206201069740683,0.7570753063743473,0.4880301099656987,1.9717947009390235,0.3017508900780304,0.6159377018946759,0.14267746792433023,0.43090764101721113,1.8920646818638314,1.0086059102080356,0.35926273373079604,-0.1796530741697238,0.9529838262623884,1.5295919290991515,-0.9503545811838279,0.544982758232892,-0.07647199667296625,0.2151517460221033,-0.5833609844142108,0.9390541618071563,3.4981163078685293,-0.6895783192988665,0.35926273373079604,1.4617845329488237,0.9111656785685303
3,220
Phospholipid metabolism
13
20
2.812139
0.004921
Q9NPH0,Q8WUK0,Q9BVG9,Q9HBU6,O14735,O95674,Q8NF37,Q6P1A2,Q9UG56,Q9C0D9,Q92604,O15120,Q9NUQ2
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
131,226,263,136,265,138,396,113,212,375,340,276,125
265,276,138,2422,1740,113,2965,396,226,340,1103,594,441,263,375,136,131,1592,125,212
1.3528340672655668,1.3118301474062795,1.8920646818638314,-0.5380402143385864,-0.19444171825613035,2.0380155210262614,-0.9813049356287264,0.9808141312665962,1.4753635194517039,1.1193918429266982,0.15719497235672153,0.6300975384411448,0.8972068072481052,1.3664840566092424,1.0224874166341895,1.9053732541087869,1.9452503290298178,-0.1206201069740683,1.9717947009390235,1.5295919290991515
3,220
Protein transmembrane import into intracellular organelle
12
15
2.810448
0.004947
Q99595,O94826,O60830,O95831,O43615,Q15388,O96008,Q92968,Q9Y5Y5,O75381,O14925,Q3ZCQ8
Processes and pathways
GO Biological process
msigdb_gobp
64,598,37,416,520,620,300,748,174,370,29,674
29,520,37,370,598,416,300,1987,771,620,674,748,64,1343,174
3.361075633693647,0.7430072800978298,3.2106974716483787,1.0224874166341895,0.6159377018946759,0.9390541618071563,1.2433090578397443,-0.313194785097642,0.4166002588713612,0.6017675204564823,0.5307604103957996,0.4452042862052327,2.663965486017274,0.011503046829603012,1.704881209746608
3,220
SLC25 family of mitochondrial transporters
15
23
2.801612
0.005085
Q9H2D1,Q6NUK1,Q9NZJ7,Q70HW3,P16260,Q9BSK2,Q9UBX3,Q9Y6C9,Q9HC21,Q96H78,P12236,Q9BQT8,Q9Y619,O43808,P12235
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
99,290,140,47,176,210,61,377,310,87,185,313,188,317,158
2641,317,575,403,158,185,176,617,703,869,290,47,87,313,210,99,752,310,140,61,778,188,377
-0.674363810312437,1.1883274006382527,0.6442470592213966,0.9669038074280564,1.7853014752695062,1.6241579565962334,1.6780073418899184,0.6017675204564823,0.4880301099656987,0.330528729857457,1.2844490111299678,2.9706691886854455,2.3140036938827615,1.2020866418225167,1.5295919290991515,2.143557307496829,0.4452042862052327,1.215836649167216,1.8920646818638314,2.689678092109702,0.4166002588713612,1.6241579565962334,1.0224874166341895
3,220
Mitochondrial carrier domain superfamily [IPR023395]
15
23
2.801612
0.005085
Q9H2D1,Q6NUK1,Q9NZJ7,Q70HW3,P16260,Q9BSK2,Q9UBX3,Q9Y6C9,Q9HC21,Q96H78,P12236,Q9BQT8,Q9Y619,O43808,P12235
Sequence
InterPro Superfamily
interpro_homologous_superfamily
99,290,140,47,176,210,61,377,310,87,185,313,188,317,158
2641,317,575,403,158,185,176,617,703,869,290,47,87,313,210,99,752,310,140,61,778,188,377
-0.674363810312437,1.1883274006382527,0.6442470592213966,0.9669038074280564,1.7853014752695062,1.6241579565962334,1.6780073418899184,0.6017675204564823,0.4880301099656987,0.330528729857457,1.2844490111299678,2.9706691886854455,2.3140036938827615,1.2020866418225167,1.5295919290991515,2.143557307496829,0.4452042862052327,1.215836649167216,1.8920646818638314,2.689678092109702,0.4166002588713612,1.6241579565962334,1.0224874166341895
3,220
Mitochondrial substrate/solute carrier [IPR018108]
15
23
2.801612
0.005085
Q9H2D1,Q6NUK1,Q9NZJ7,Q70HW3,P16260,Q9BSK2,Q9UBX3,Q9Y6C9,Q9HC21,Q96H78,P12236,Q9BQT8,Q9Y619,O43808,P12235
Sequence
InterPro Repeat
interpro_repeat
99,290,140,47,176,210,61,377,310,87,185,313,188,317,158
2641,317,575,403,158,185,176,617,703,869,290,47,87,313,210,99,752,310,140,61,778,188,377
-0.674363810312437,1.1883274006382527,0.6442470592213966,0.9669038074280564,1.7853014752695062,1.6241579565962334,1.6780073418899184,0.6017675204564823,0.4880301099656987,0.330528729857457,1.2844490111299678,2.9706691886854455,2.3140036938827615,1.2020866418225167,1.5295919290991515,2.143557307496829,0.4452042862052327,1.215836649167216,1.8920646818638314,2.689678092109702,0.4166002588713612,1.6241579565962334,1.0224874166341895
3,220
Nucleobase containing compound transmembrane transporter activity
11
14
2.791731
0.005243
Q9H2D1,Q6NUK1,L0R6Q1,Q8TB61,Q9BSK2,Q9HC21,P05141,P12236,P12235,O43808,O00400
Functions
GO Molecular function
msigdb_gomf
99,290,102,104,210,310,403,185,158,317,62
102,62,317,403,158,185,426,3175,868,290,104,210,99,310
2.090849287701112,2.6768253453241613,1.1883274006382527,0.9669038074280564,1.7853014752695062,1.6241579565962334,0.9251147879781412,-1.9556055796511111,0.330528729857457,1.2844490111299678,2.090849287701112,1.5295919290991515,2.143557307496829,1.215836649167216
3,220
Macromolecule transmembrane transporter activity
6
13
2.788418
0.005297
Q99595,O60830,Q9NS69,Q9Y584,O14925,Q07820
Functions
GO Molecular function
msigdb_gomf
64,37,21,23,29,222
29,37,598,300,511,868,1209,222,620,64,21,1022,23
3.361075633693647,3.2106974716483787,0.6159377018946759,1.2433090578397443,0.7711332727194923,0.330528729857457,0.08449317262514162,1.4889337304892023,0.6017675204564823,2.663965486017274,3.5973077301556384,0.2151517460221033,3.5725469272262074
3,220
Establishment of protein localization to mitochondrial membrane
12
20
2.779078
0.005451
Q07812,Q9Y512,Q15070,Q8N8Q8,Q8WWC4,Q53H12,Q9Y5J6,Q9Y5J9,O00203,Q9NS69,Q9Y584,P62072
Processes and pathways
GO Biological process
msigdb_gobp
354,323,42,139,172,204,346,181,433,21,23,26
433,670,598,1325,727,2935,2135,26,354,42,204,139,172,21,1252,477,323,23,346,181
0.9111656785685303,0.5307604103957996,0.6159377018946759,0.011503046829603012,0.4594902255077705,-0.9503545811838279,-0.387822311164995,3.448371427949981,1.0779181486196767,3.0972988744230174,1.5566539160615283,1.8920646818638314,1.704881209746608,3.5973077301556384,0.06991835486739327,0.8412731718875827,1.174558901603863,3.5725469272262074,1.1055766906461557,1.6510996458924831
3,220
Phospholipid biosynthesis
12
19
2.767355
0.005651
Q8WUK0,Q9BVG9,Q9HBU6,O14735,O95674,Q8NF37,Q6P1A2,Q9UG56,Q9C0D9,Q92604,O15120,Q9NUQ2
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
226,263,136,265,138,396,113,212,375,340,276,125
265,276,138,2422,1740,113,2965,396,226,340,1103,594,441,263,375,136,1592,125,212
1.3528340672655668,1.3118301474062795,1.8920646818638314,-0.5380402143385864,-0.19444171825613035,2.0380155210262614,-0.9813049356287264,0.9808141312665962,1.4753635194517039,1.1193918429266982,0.15719497235672153,0.6300975384411448,0.8972068072481052,1.3664840566092424,1.0224874166341895,1.9053732541087869,-0.1206201069740683,1.9717947009390235,1.5295919290991515
3,220
SNARE protein
6
14
2.759194
0.005794
O14653,O95249,O60499,P56962,O43752,Q9P2W9
Functions
Panther Protein class
panther_protein_class
225,73,118,214,249,31
2593,225,1109,249,118,73,1429,772,214,372,672,1216,31,1497
-0.6439755827313389,1.4753635194517039,0.14267746792433023,1.4073803914068117,2.0115511185478705,2.52203320891506,-0.04709964827475354,0.4166002588713612,1.5160479135785023,1.0224874166341895,0.5307604103957996,0.08449317262514162,3.3485794389162113,-0.07647199667296625
3,220
SNARE protein
6
14
2.759194
0.005794
O14653,O95249,O60499,P56962,O43752,Q9P2W9
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
225,73,118,214,249,31
2593,225,1109,249,118,73,1429,772,214,372,672,1216,31,1497
-0.6439755827313389,1.4753635194517039,0.14267746792433023,1.4073803914068117,2.0115511185478705,2.52203320891506,-0.04709964827475354,0.4166002588713612,1.5160479135785023,1.0224874166341895,0.5307604103957996,0.08449317262514162,3.3485794389162113,-0.07647199667296625
3,220
O acyltransferase activity
12
15
2.742774
0.006092
Q8NCC3,O15228,Q8NF37,Q6P1A2,Q96AD5,P35610,Q92604,Q99943,O15120,P23786,P50416,Q9NUQ2
Functions
GO Molecular function
msigdb_gomf
581,353,396,113,566,271,340,441,276,182,213,125
276,353,182,2527,271,213,113,2965,581,396,340,566,594,441,125
1.3118301474062795,1.0779181486196767,1.6376330607839327,-0.5984945173388617,1.3255071355722057,1.5160479135785023,2.0380155210262614,-0.9813049356287264,0.6442470592213966,0.9808141312665962,1.1193918429266982,0.6725152692738572,0.6300975384411448,0.8972068072481052,1.9717947009390235
3,220
Protein transmembrane transporter activity
6
12
2.740469
0.006135
Q99595,O60830,Q9NS69,Q9Y584,O14925,Q07820
Functions
GO Molecular function
msigdb_gomf
64,37,21,23,29,222
29,37,598,300,511,1209,222,620,64,21,1022,23
3.361075633693647,3.2106974716483787,0.6159377018946759,1.2433090578397443,0.7711332727194923,0.08449317262514162,1.4889337304892023,0.6017675204564823,2.663965486017274,3.5973077301556384,0.2151517460221033,3.5725469272262074
3,220
Nucleotide transport
11
13
2.722229
0.006484
Q9H2D1,Q6NUK1,Q8TB61,Q9BSK2,Q9HC21,P05141,P12236,P12235,O43808,O00400,Q08722
Processes and pathways
GO Biological process
msigdb_gobp
99,290,104,210,310,403,185,158,317,62,255
62,317,403,158,185,426,3175,255,290,104,210,99,310
2.6768253453241613,1.1883274006382527,0.9669038074280564,1.7853014752695062,1.6241579565962334,0.9251147879781412,-1.9556055796511111,1.3937571960734862,1.2844490111299678,2.090849287701112,1.5295919290991515,2.143557307496829,1.215836649167216
3,220
Calcium import into the mitochondrion
6
8
2.692331
0.007095
Q9H4I9,P21796,Q8WWC4,Q8IYU8,Q9BPX6,Q96AQ8
Processes and pathways
GO Biological process
msigdb_gobp
38,70,172,175,342,282
70,175,406,172,282,342,38,1281
2.5995589664368004,1.6914484940680552,0.9669038074280564,1.704881209746608,1.3118301474062795,1.1193918429266982,3.2106974716483787,0.055331969068424594
3,220
Respiratory chain complex iv assembly
6
9
2.67005
0.007584
Q9P0S2,Q15070,Q8N8Q8,O75880,Q7KZN9,Q9Y2R0
Processes and pathways
GO Biological process
msigdb_gobp
10,42,139,298,251,122
1253,298,42,251,139,1396,10,477,122
0.055331969068424594,1.2433090578397443,3.0972988744230174,1.4073803914068117,1.8920646818638314,-0.01777473199075143,4.3291217026971225,0.8412731718875827,1.9850548401175079
3,220
Intrinsic component of mitochondrial outer membrane
9
13
2.669507
0.007596
O94826,Q8IWA4,Q8TB36,Q9BWH2,Q8IXI1,O96008,Q9UH62,P57105,P50416
Localization
GO Cellular component
msigdb_gocc
598,364,593,500,591,300,468,84,213
598,1201,300,213,84,620,364,591,1585,593,500,936,468
0.6159377018946759,0.08449317262514162,1.2433090578397443,1.5160479135785023,2.3661898889393695,0.6017675204564823,1.06407470918364,0.6300975384411448,-0.1206201069740683,0.6300975384411448,0.7992191364595662,0.28734545070934525,0.8552713566510017
3,220
Cis golgi network
9
17
2.665552
0.007686
P24390,O95249,P98194,Q8TBA6,Q9Y3A6,Q9NPR9,Q96JB2,O43731,O00461
Localization
GO Cellular component
msigdb_gocc
164,73,429,397,344,178,253,92,159
159,1560,92,73,164,1636,511,429,928,1170,2086,397,2821,1883,253,178,344
1.7719189526049448,-0.1206201069740683,2.2092672490607383,2.52203320891506,1.7451289416289844,-0.15011234602282414,0.7711332727194923,0.9251147879781412,0.28734545070934525,0.11360824532721736,-0.35793329427295245,0.9808141312665962,-0.8117901676292918,-0.2537190743102173,1.4073803914068117,1.6780073418899184,1.1193918429266982
3,220
Mitochondrial carrier protein [IPR002067]
12
13
2.658073
0.007859
P05141,O75746,Q6NUK1,Q9H936,P53007,P16260,Q9HC21,Q96H78,P12236,Q9BQT8,O43808,P12235
Sequence
InterPro Family
interpro_family
403,575,290,752,617,176,310,87,185,313,317,158
317,575,403,158,185,176,617,290,87,313,752,310,778
1.1883274006382527,0.6442470592213966,0.9669038074280564,1.7853014752695062,1.6241579565962334,1.6780073418899184,0.6017675204564823,1.2844490111299678,2.3140036938827615,1.2020866418225167,0.4452042862052327,1.215836649167216,0.4166002588713612
3,220
Synthesis of pa
8
10
2.636889
0.008367
O15228,Q9NPH0,Q8N2A8,O94830,Q8NF37,Q99943,O15120,Q9NUQ2
Processes and pathways
Reactome Pathways
msigdb_reactome
353,131,67,402,396,441,276,125
276,353,402,578,67,1365,396,441,131,125
1.3118301474062795,1.0779181486196767,0.9669038074280564,0.6442470592213966,2.62534308033295,-0.003129968688779517,0.9808141312665962,0.8972068072481052,1.9452503290298178,1.9717947009390235
3,220
Organelle membrane contact site
11
17
2.635522
0.008401
Q9NTJ5,P51572,Q96S66,Q96N66,Q15388,O96008,Q5XKP0,P27824,O95772,Q9Y320,P56962
Localization
GO Cellular component
msigdb_gocc
518,485,653,594,620,300,16,236,85,216,214
657,1727,1094,85,300,236,485,214,620,16,1172,594,653,933,2509,518,216
0.544982758232892,-0.19444171825613035,0.15719497235672153,2.3531546237426215,1.2433090578397443,1.4346001455642394,0.8132470889449575,1.5160479135785023,0.6017675204564823,3.7822378308851308,0.11360824532721736,0.6300975384411448,0.5591946133780552,0.28734545070934525,-0.5833609844142108,0.7570753063743473,1.5160479135785023
3,220
secondary carrier transporter
10
15
2.627805
0.008594
O75746,Q8TB61,Q9H936,O14975,Q96H78,Q6P1M0,Q9BQT8,O95202,Q9UBX3,O00400
Functions
Panther Protein class
panther_protein_class
575,104,752,460,87,735,313,124,61,62
62,460,575,124,1208,869,735,104,1065,87,313,752,61,778,977
2.6768253453241613,0.8552713566510017,0.6442470592213966,1.9717947009390235,0.08449317262514162,0.330528729857457,0.4594902255077705,2.090849287701112,0.1861959397352981,2.3140036938827615,1.2020866418225167,0.4452042862052327,2.689678092109702,0.4166002588713612,0.25850136951980746
3,220