term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monovalent inorganic cation homeostasis | 21 | 31 | 3.291315 | 0.000997 | Q9HC07,P55011,P05023,Q9Y6M7,Q8N511,P04920,Q96PU5,Q93050,P50897,Q9P0T7,Q92544,O75787,Q15904,Q14964,P04899,Q92581,P54709,Q9Y487,O75503,P51790,P51149 | Processes and pathways | GO Biological process | msigdb_gobp | 128,390,394,403,270,275,287,171,53,64,323,320,209,465,587,214,480,360,104,239,502 | 104,320,587,275,394,1687,1096,2105,1507,53,502,239,480,390,604,465,209,270,323,214,171,760,287,763,128,64,1200,1873,360,1324,403 | 2.2835694069887835,1.2636815408562456,0.6173184799051494,1.4721773650526246,1.0570844850930035,-0.2587130568814146,0.059377376010689153,-0.45433286929698796,-0.17723144136555438,2.616602358730607,0.7866818484921456,1.6633788128540579,0.8419112349230434,1.0676115247162676,0.5943047502828036,0.8965525637862654,1.765685690904278,1.5109728694831275,1.2636815408562456,1.7472293962722831,1.937928245362595,0.358212818135691,1.4035922338561988,0.358212818135691,2.18215929435381,2.553174480013193,-0.005212952459059928,-0.32767317867730517,1.1510683617802193,-0.07066185389454786,1.0465360280824727 | 3,053 |
Anion transmembrane transport | 25 | 43 | 3.284422 | 0.001022 | P55011,P45880,P05556,P05141,P51798,Q9Y6M7,O75915,P04920,P21796,O60831,Q9HC21,Q9Y619,Q8TB61,P98164,P08195,P30825,Q92581,Q9H2D1,P12235,P12236,Q9UHG3,Q9UBX3,P51790,Q4KMQ2,Q9Y277 | Processes and pathways | GO Biological process | msigdb_gobp | 390,135,524,395,269,403,523,275,151,540,299,180,68,196,328,79,214,92,100,103,235,113,239,244,251 | 538,540,2401,523,275,395,524,1057,328,100,103,151,79,1207,135,239,269,720,819,390,196,1637,808,1101,613,244,2413,68,214,1674,763,92,1067,652,299,726,113,235,913,251,1915,180,403 | 0.6970555073651654,0.6970555073651654,-0.613809285254711,0.7308499991523034,1.4721773650526246,1.0570844850930035,0.7308499991523034,0.09772985746096338,1.2433861353171847,2.308631386581677,2.291936121589696,2.0439466216934568,2.432256446318069,-0.018233230344920522,2.1393434129981372,1.6633788128540579,1.5109728694831275,0.40632489423308854,0.2974158983461496,1.0676115247162676,1.8297870381814723,-0.2314007759263953,0.30963451704569495,0.059377376010689153,0.5827586084337831,1.6445651501196628,-0.613809285254711,2.513161047727077,1.7472293962722831,-0.24503774966773847,0.358212818135691,2.350148936285125,0.09772985746096338,0.5246297166579437,1.3540507039260963,0.40632489423308854,2.26679759515337,1.6727608132509426,0.21103780546535914,1.625684832355376,-0.34158367124160455,1.9110956664873515,1.0465360280824727 | 3,053 |
Carbohydrate derivative transport | 14 | 18 | 3.282475 | 0.001029 | P12235,P61916,L0R6Q1,P12236,Q8TB61,Q8WTV0,P98155,P05141,Q9HC21,Q6NUK1,Q08722,P07602,O00400,Q9NZJ7 | Processes and pathways | GO Biological process | msigdb_gobp | 100,261,511,103,68,359,40,395,299,332,140,21,508,351 | 511,508,538,395,21,100,103,1207,261,40,140,2413,332,68,359,713,299,351 | 0.7644222293835908,0.7755641462351951,0.6970555073651654,1.0570844850930035,3.0195749043603826,2.308631386581677,2.291936121589696,-0.018233230344920522,1.5494862574126163,2.7181568448827473,2.1048469198732267,-0.613809285254711,1.2332088294189667,2.513161047727077,1.1510683617802193,0.43020921375824495,1.3540507039260963,1.192300224783089 | 3,053 |
Recycling endosome membrane | 11 | 21 | 3.280646 | 0.001036 | Q9H223,P01889,P02786,P10321,P04439,O15127,O14828,Q92673,Q92581,Q86Y82,Q9H4M9 | Localization | GO Cellular component | msigdb_gocc | 357,325,36,165,105,147,369,54,214,246,377 | 369,582,147,325,36,105,165,1972,1149,795,1541,1662,1208,776,246,214,54,444,357,377,1529 | 1.1095074471795692,0.6287863334786191,2.070130363883016,1.2535436771356345,2.779747026833827,2.2835694069887835,1.9557428487590485,-0.38355670174670764,0.020724788531935035,0.3218233565713564,-0.19071746259586272,-0.24503774966773847,-0.018233230344920522,0.34611234668124813,1.635133356253012,1.7472293962722831,2.616602358730607,0.9398515677513489,1.1614069470810378,1.099065109888305,-0.17723144136555438 | 3,053 |
Early endosome membrane | 20 | 47 | 3.274957 | 0.001057 | Q9HC07,Q8N4V1,Q8IV08,Q15043,Q96J02,P10321,P61020,O15400,Q92673,P01889,Q06481,Q04656,P00533,Q92581,Q9H223,P04439,Q9NV96,P51790,Q86Y82,Q9H4M9 | Localization | GO Cellular component | msigdb_gocc | 128,267,14,407,281,165,166,169,54,325,74,203,335,214,357,105,106,239,246,377 | 914,169,1232,942,1656,335,325,2985,105,165,514,406,239,166,1541,1662,968,203,74,1087,1382,2497,407,1191,1011,1491,246,657,14,267,214,54,860,281,527,849,2088,357,1935,377,128,106,1318,1052,981,1419,1324 | 0.19857493350037805,1.937928245362595,-0.03128805197937675,0.17355509404966507,-0.24503774966773847,1.2230116728735583,1.2535436771356345,-1.5037706134431923,2.2835694069887835,1.9557428487590485,0.7644222293835908,1.0359660555856258,1.6633788128540579,1.9557428487590485,-0.19071746259586272,-0.24503774966773847,0.16099777070340407,1.7840786381977862,2.4566523252294235,0.0721946227962857,-0.1103540999259057,-0.6731449738170256,1.0359660555856258,-0.005212952459059928,0.13578741527968066,-0.16378257437491706,1.635133356253012,0.512923337475363,3.135780580137371,1.5206274845608097,1.7472293962722831,2.616602358730607,0.26057972136771734,1.433095060674533,0.7308499991523034,0.2728886665037662,-0.4400942588347924,1.1614069470810378,-0.35553424861853866,1.099065109888305,2.18215929435381,2.2835694069887835,-0.07066185389454786,0.11044822745697883,0.16099777070340407,-0.12365661898489545,-0.07066185389454786 | 3,053 |
Anion transmembrane transporter activity | 25 | 48 | 3.274704 | 0.001058 | Q96QD8,P55011,P45880,P05141,P51798,Q9Y6M7,P04920,Q9C0H2,P21796,Q9HC21,Q9Y619,Q8TB61,P08195,Q6NUK1,P30825,Q92581,Q9H813,Q9H2D1,P12235,P12236,Q9UBX3,P51790,P11166,Q4KMQ2,Q9Y277 | Functions | GO Molecular function | msigdb_gomf | 259,390,135,395,269,403,275,19,151,299,180,68,328,332,79,214,89,92,100,103,113,239,243,244,251 | 2589,508,1595,538,2401,275,395,328,1096,243,100,103,151,79,1207,135,239,269,720,819,390,808,407,613,244,3005,2413,332,1953,68,214,1674,259,675,713,763,19,92,89,1067,652,299,765,113,913,251,180,403 | -0.7483704240161151,0.7755641462351951,-0.21780189519795196,0.6970555073651654,-0.613809285254711,1.4721773650526246,1.0570844850930035,1.2433861353171847,0.059377376010689153,1.6445651501196628,2.308631386581677,2.291936121589696,2.0439466216934568,2.432256446318069,-0.018233230344920522,2.1393434129981372,1.6633788128540579,1.5109728694831275,0.40632489423308854,0.2974158983461496,1.0676115247162676,0.30963451704569495,1.0359660555856258,0.5827586084337831,1.6445651501196628,-1.6857818609693211,-0.613809285254711,1.2332088294189667,-0.3695251711327288,2.513161047727077,1.7472293962722831,-0.24503774966773847,1.5590710612555858,0.477640468160584,0.43020921375824495,0.358212818135691,3.0342313533271863,2.350148936285125,2.3749098883187894,0.09772985746096338,0.5246297166579437,1.3540507039260963,0.358212818135691,2.26679759515337,0.21103780546535914,1.625684832355376,1.9110956664873515,1.0465360280824727 | 3,053 |
Phagocytic vesicle membrane | 15 | 22 | 3.264692 | 0.001096 | P20339,P51809,Q9BZG1,P10321,P01889,Q9Y487,Q93050,P04439,Q06481,Q04656,Q03518,Q14964,P11279,P51149,P51151 | Localization | GO Cellular component | msigdb_gocc | 514,353,579,165,325,360,171,105,74,203,234,465,121,502,542 | 1325,790,325,105,165,121,514,1430,966,502,542,353,795,604,968,234,203,74,465,171,579,360 | -0.08385693476833972,0.3218233565713564,1.2535436771356345,2.2835694069887835,1.9557428487590485,2.2161719066574945,0.7644222293835908,-0.13699538899316593,0.16099777070340407,0.7866818484921456,0.6970555073651654,1.1717250589049941,0.3218233565713564,0.5943047502828036,0.16099777070340407,1.6727608132509426,1.7840786381977862,2.4566523252294235,0.8965525637862654,1.937928245362595,0.6402283550178628,1.1510683617802193 | 3,053 |
Outer membrane | 35 | 80 | 3.251134 | 0.001149 | Q9NS69,P52789,Q8N4H5,P09601,O96008,P45880,O43169,Q9BUR5,Q9Y6C9,Q9Y512,Q6UXV4,Q13505,Q9NQZ5,P21796,Q8WY22,Q96TC7,Q16891,Q99720,P42345,Q9NVH1,Q53H12,Q9NZ45,P00387,Q07820,Q8IWA4,O00264,P50402,Q9NZJ7,Q6NUM9,P57105,O00429,Q9BWH2,O60313,Q9Y277,Q5XKP0 | Localization | GO Cellular component | msigdb_gocc | 1,257,5,133,519,135,12,268,402,531,534,23,537,151,156,544,416,298,554,448,571,194,583,592,467,340,476,351,481,503,622,498,371,251,250 | 340,622,3026,12,371,965,1502,780,1423,1081,519,583,2908,877,133,2514,151,1128,2969,554,2561,135,476,257,2740,503,1336,1979,592,23,2822,690,2412,416,571,1490,250,481,534,701,1955,467,799,1469,785,5,2831,1295,832,1673,156,1218,1864,544,1611,926,298,717,268,1613,498,2092,2853,1615,537,1,1444,448,912,1025,959,194,351,632,767,1080,251,1276,531,402 | 1.2127945785226133,0.5595870981994009,-2.410247884772447,3.2355507913615793,1.1095074471795692,0.16099777070340407,-0.17723144136555438,0.33398257941175047,-0.13699538899316593,0.0721946227962857,0.7420652759647238,0.6287863334786191,-1.1601538119786206,0.23587033191152165,2.1479335171777034,-0.688095106410563,2.0439466216934568,0.03364265519892447,-1.363225981446116,0.674400725375824,-0.7181371319149215,2.1393434129981372,0.8528860938012238,1.5686385889352172,-0.8868625525092045,0.7866818484921456,-0.08385693476833972,-0.38355670174670764,0.6173184799051494,3.004880449945332,-0.9974667036146205,0.4539806748878796,-0.613809285254711,1.01476116822825,0.6516446748258692,-0.16378257437491706,1.625684832355376,0.8419112349230434,0.7083452377706503,0.44210897675379346,-0.3695251711327288,0.8856706691345428,0.3218233565713564,-0.15037063254699395,0.33398257941175047,3.4231907179791325,-1.0134824950248342,-0.05750215436707501,0.28516733659390786,-0.24503774966773847,2.0351905672615014,-0.018233230344920522,-0.32767317867730517,0.6970555073651654,-0.21780189519795196,0.19857493350037805,1.363996390617815,0.4182812364739646,1.5206274845608097,-0.21780189519795196,0.7977754540117483,-0.4400942588347924,-1.0456796307190568,-0.21780189519795196,0.7083452377706503,3.6708025762594803,-0.13699538899316593,0.9398515677513489,0.21103780546535914,0.1231340177911712,0.17355509404966507,1.8388822290459017,1.192300224783089,0.5595870981994009,0.358212818135691,0.0849787193065716,1.625684832355376,-0.044377623849349325,0.7196100272359108,1.0465360280824727 | 3,053 |
Metal ion transmembrane transporter activity | 15 | 25 | 3.245641 | 0.001172 | Q9HC07,Q96QD8,P06756,P55011,P08195,P05023,Q8N4V1,P16615,Q04656,Q9Y6M7,Q92581,Q8IUH4,Q15043,Q9HD20,O95202 | Functions | GO Molecular function | msigdb_gomf | 128,259,195,390,328,394,267,202,203,403,214,279,407,182,249 | 249,394,195,2707,1752,328,202,440,390,948,918,203,407,279,267,1340,214,2201,259,763,731,128,182,1069,403 | 1.625684832355376,1.0570844850930035,1.8297870381814723,-0.8557335336316402,-0.2861796454358755,1.2433861353171847,1.7932515087502272,0.9398515677513489,1.0676115247162676,0.17355509404966507,0.19857493350037805,1.7840786381977862,1.0359660555856258,1.4526723602880829,1.5206274845608097,-0.08385693476833972,1.7472293962722831,-0.49730329369665177,1.5590710612555858,0.358212818135691,0.3943400351131716,2.18215929435381,1.9021217402473265,0.09772985746096338,1.0465360280824727 | 3,053 |
Apical part of cell | 27 | 58 | 3.239166 | 0.001199 | Q16625,P55011,P05023,Q9Y6M7,O00592,P04920,Q15043,Q13277,P07858,P05067,Q86UE4,P19022,Q14254,P01130,P20020,O75787,P98164,P08195,Q99538,Q04656,P30825,Q9NV96,O75955,P51790,P11166,P41208,P36543 | Localization | GO Cellular component | msigdb_gocc | 134,390,394,403,146,275,407,154,27,29,33,418,432,188,440,320,196,328,201,203,79,106,363,239,243,117,381 | 680,146,1281,2279,320,363,188,2985,275,394,29,27,1057,328,1349,1627,243,2018,2182,418,440,1428,2735,2104,79,890,1883,381,1483,2107,117,1207,239,819,480,390,1817,604,196,203,1380,154,2761,1435,432,407,533,1930,134,33,201,823,713,671,106,814,1397,403 | 0.4658244563610143,2.070130363883016,-0.05750215436707501,-0.5552019842727006,1.2636815408562456,1.1303294043028353,1.866075878935031,-1.5037706134431923,1.4721773650526246,1.0570844850930035,2.8859295440854202,2.9233715788819468,0.09772985746096338,1.2433861353171847,-0.09708761132484221,-0.2314007759263953,1.6445651501196628,-0.41174265253282316,-0.49730329369665177,1.0041260536406191,0.9398515677513489,-0.13699538899316593,-0.8868625525092045,-0.45433286929698796,2.432256446318069,0.22346954691003423,-0.34158367124160455,1.088601740735695,-0.16378257437491706,-0.45433286929698796,2.2415432585124297,-0.018233230344920522,1.6633788128540579,0.2974158983461496,0.8419112349230434,1.0676115247162676,-0.31380251320317754,0.5943047502828036,1.8297870381814723,1.7840786381977862,-0.1103540999259057,2.0351905672615014,-0.9181987971791161,-0.13699538899316593,0.9613654253667215,1.0359660555856258,0.7083452377706503,-0.35553424861853866,2.1479335171777034,2.8254996778955275,1.8024087243316227,0.2974158983461496,0.43020921375824495,0.4894288560742516,2.2835694069887835,0.30963451704569495,-0.1103540999259057,1.0465360280824727 | 3,053 |
Glycosaminoglycan metabolism | 9 | 14 | 3.230259 | 0.001237 | P54802,Q8TB61,P16278,P06865,P07686,Q7LGA3,O43505,P15586,Q9Y251 | Processes and pathways | Reactome Pathways | msigdb_reactome | 160,68,73,72,208,24,220,184,223 | 1625,220,2784,72,208,241,184,73,160,24,68,870,1200,223 | -0.2314007759263953,1.7194251000762824,-0.9497453913983102,2.4728566349196144,1.765685690904278,1.6539802803309698,1.8841289535850934,2.4728566349196144,1.9823551672513169,2.9679765780397287,2.513161047727077,0.2482403330382631,-0.005212952459059928,1.710124790825368 | 3,053 |
Active ion transmembrane transporter activity | 24 | 42 | 3.228184 | 0.001246 | Q96QD8,P55011,P05023,P05141,P51798,Q9Y6M7,Q7KZN9,P04920,Q15526,Q15043,Q9UDW1,Q9HD20,P20020,P08195,P16615,Q04656,P00403,Q92581,P12235,P12236,P51790,O95202,P13073,P36543 | Functions | GO Molecular function | msigdb_gomf | 259,390,394,395,269,403,143,275,408,407,183,182,440,328,202,203,463,214,100,103,239,249,380,381 | 508,249,463,275,394,395,1687,328,755,1628,100,103,380,202,440,1097,1428,2735,2045,381,2107,1207,239,269,720,390,604,1637,808,203,407,408,143,214,1772,259,763,1067,182,183,1873,403 | 0.7755641462351951,1.625684832355376,0.8965525637862654,1.4721773650526246,1.0570844850930035,1.0570844850930035,-0.2587130568814146,1.2433861353171847,0.358212818135691,-0.2314007759263953,2.308631386581677,2.291936121589696,1.088601740735695,1.7932515087502272,0.9398515677513489,0.059377376010689153,-0.13699538899316593,-0.8868625525092045,-0.42589761215042704,1.088601740735695,-0.45433286929698796,-0.018233230344920522,1.6633788128540579,1.5109728694831275,0.40632489423308854,1.0676115247162676,0.5943047502828036,-0.2314007759263953,0.30963451704569495,1.7840786381977862,1.0359660555856258,1.0359660555856258,2.087516346686594,1.7472293962722831,-0.2861796454358755,1.5590710612555858,0.358212818135691,0.09772985746096338,1.9021217402473265,1.9021217402473265,-0.32767317867730517,1.0465360280824727 | 3,053 |
Coated vesicle membrane | 20 | 61 | 3.218476 | 0.001289 | O43731,O43493,Q8N511,P04114,Q9NR31,P24390,P02786,P10321,Q9Y6B6,P20645,P01130,P98164,P01889,Q9Y3B3,P00533,Q14108,Q13190,P51809,P04439,P11717 | Localization | GO Cellular component | msigdb_gocc | 0,3,270,144,284,37,36,165,313,312,188,196,325,330,335,213,225,353,105,109 | 1229,1938,1716,1326,3,0,1533,1879,943,790,2369,1598,1450,2590,1451,335,188,325,36,144,105,1059,854,165,1922,109,514,312,37,793,1600,697,603,353,2864,2266,946,2455,1571,1761,196,2213,225,213,1154,776,374,1605,270,1861,636,284,851,1198,2572,1302,2036,330,736,313,1251 | -0.03128805197937675,-0.3695251711327288,-0.27242694039497706,-0.08385693476833972,3.585003342735257,3.7488958239943146,-0.19071746259586272,-0.34158367124160455,0.17355509404966507,0.3218233565713564,-0.5990899607250865,-0.21780189519795196,-0.15037063254699395,-0.7483704240161151,-0.15037063254699395,1.2230116728735583,1.866075878935031,1.2535436771356345,2.779747026833827,2.0788303063459717,2.2835694069887835,0.09772985746096338,0.26057972136771734,1.9557428487590485,-0.35553424861853866,2.26679759515337,0.7644222293835908,1.3040379142045533,2.779747026833827,0.3218233565713564,-0.21780189519795196,0.44210897675379346,0.5943047502828036,1.1717250589049941,-1.0618618334058418,-0.5406616335135016,0.17355509404966507,-0.6433848115667744,-0.20424086935988572,-0.2861796454358755,1.8297870381814723,-0.511712584314456,1.7008082712982846,1.7472293962722831,0.020724788531935035,0.34611234668124813,1.1095074471795692,-0.21780189519795196,1.5109728694831275,-0.32767317867730517,0.5479614575971996,1.423279111691743,0.2728886665037662,-0.005212952459059928,-0.7181371319149215,-0.05750215436707501,-0.41174265253282316,1.2433861353171847,0.3943400351131716,1.3040379142045533,-0.03128805197937675 | 3,053 |
External side of plasma membrane | 17 | 29 | 3.213091 | 0.001313 | Q8IX05,P06756,O75787,P02786,P98164,P42892,O75955,Q7KYR7,P43121,P14672,P51790,Q08431,P11279,O96005,P07858,P01130,Q5ZPR3 | Localization | GO Cellular component | msigdb_gocc | 2,195,320,36,196,101,363,364,238,301,239,278,121,215,27,188,157 | 320,363,215,1331,188,36,2985,524,195,405,27,1057,121,301,2210,2996,1430,1207,101,238,1660,239,196,278,1190,1705,157,364,2 | 1.2636815408562456,1.1303294043028353,1.737977340170717,-0.08385693476833972,1.866075878935031,2.779747026833827,-1.5037706134431923,0.7308499991523034,1.8297870381814723,1.0359660555856258,2.9233715788819468,0.09772985746096338,2.2161719066574945,1.3440861679024063,-0.511712584314456,-1.6120978916093172,-0.13699538899316593,-0.018233230344920522,2.300290100303094,1.6633788128540579,-0.24503774966773847,1.6633788128540579,1.8297870381814723,1.4526723602880829,-0.005212952459059928,-0.2587130568814146,2.0088372660094183,1.1303294043028353,3.6247603290177213 | 3,053 |
Intrinsic component of endoplasmic reticulum membrane | 26 | 48 | 3.202884 | 0.001361 | O75844,Q8N4V1,O95470,Q9Y282,Q9BUN8,Q96A33,P10321,P27824,Q9H490,Q9NQC3,Q8TB61,P01889,P57088,Q9HCU5,Q15629,Q92643,Q9P035,P04439,Q03518,O43292,Q8TCT9,O76024,Q86XL3,Q9NZ01,Q9Y4P3,Q8TCT8 | Localization | GO Cellular component | msigdb_gocc | 130,267,397,25,282,285,165,425,186,60,68,325,452,470,217,342,486,105,234,495,367,372,242,378,384,125 | 886,1054,495,1747,130,372,397,325,105,165,1430,425,1972,644,452,948,234,1463,1766,217,2413,2081,242,267,910,68,125,367,342,2166,712,285,2302,535,1869,282,186,470,1024,60,378,486,2806,767,1069,25,384,983 | 0.22346954691003423,0.09772985746096338,0.7977754540117483,-0.2861796454358755,2.173622951248582,1.1095074471795692,1.0465360280824727,1.2535436771356345,2.2835694069887835,1.9557428487590485,-0.13699538899316593,0.9827899779325561,-0.38355670174670764,0.5246297166579437,0.9182475647792882,0.17355509404966507,1.6727608132509426,-0.15037063254699395,-0.2861796454358755,1.737977340170717,-0.613809285254711,-0.4400942588347924,1.6539802803309698,1.5206274845608097,0.21103780546535914,2.513161047727077,2.1906823149730266,1.1199288473059854,1.2127945785226133,-0.4829371027702765,0.43020921375824495,1.4134448616858115,-0.5552019842727006,0.7083452377706503,-0.32767317867730517,1.433095060674533,1.8751099806041622,0.8747656995030354,0.1231340177911712,2.577044818596751,1.099065109888305,0.830912855432633,-0.965598565884847,0.358212818135691,0.09772985746096338,2.953147342760977,1.088601740735695,0.16099777070340407 | 3,053 |
Endoplasmic reticulum golgi intermediate compartment membrane | 19 | 25 | 3.201707 | 0.001366 | P51572,Q8N511,Q9Y282,P24390,P53634,Q9H0U4,O95070,Q10472,P49257,Q9Y3B3,Q15904,P26572,P61019,P49755,Q13190,O15260,Q03518,Q12907,Q15363 | Localization | GO Cellular component | msigdb_gocc | 644,270,25,37,170,560,303,178,697,330,209,464,590,603,225,227,234,625,374 | 227,916,790,303,37,464,1430,697,603,644,170,590,234,178,625,225,374,209,270,712,1065,560,25,1017,330 | 1.6914754779087535,0.19857493350037805,0.3218233565713564,1.334102702134965,2.779747026833827,0.8965525637862654,-0.13699538899316593,0.44210897675379346,0.5943047502828036,0.5246297166579437,1.937928245362595,0.6173184799051494,1.6727608132509426,1.9110956664873515,0.5595870981994009,1.7008082712982846,1.1095074471795692,1.765685690904278,1.5109728694831275,0.43020921375824495,0.09772985746096338,0.674400725375824,2.953147342760977,0.13578741527968066,1.2433861353171847 | 3,053 |
SLC superfamily of solute carriers | 26 | 47 | 3.189438 | 0.001425 | Q9HC07,Q96QD8,P55011,Q70HW3,P05141,Q9Y6M7,Q9Y6C9,P04920,Q8NEW0,Q9HC21,P14672,Q9Y619,Q8TB61,P08195,Q6NUK1,P30825,Q7L0J3,Q92581,Q9H2D1,Q9BSK2,Q9NZJ7,P12235,P12236,Q9UBX3,P11166,O95202 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 128,259,390,266,395,403,402,275,32,299,301,180,68,328,332,79,80,214,92,95,351,100,103,113,243,249 | 508,3007,538,2401,249,275,395,328,243,100,103,301,79,1207,720,819,390,1637,808,407,613,3005,332,1953,266,80,492,32,68,214,1674,259,713,95,763,731,92,1067,652,128,299,351,113,913,180,402,403 | 0.7755641462351951,-1.7418453203119433,0.6970555073651654,-0.613809285254711,1.625684832355376,1.4721773650526246,1.0570844850930035,1.2433861353171847,1.6445651501196628,2.308631386581677,2.291936121589696,1.3440861679024063,2.432256446318069,-0.018233230344920522,0.40632489423308854,0.2974158983461496,1.0676115247162676,-0.2314007759263953,0.30963451704569495,1.0359660555856258,0.5827586084337831,-1.6857818609693211,1.2332088294189667,-0.3695251711327288,1.5206274845608097,2.432256446318069,0.8088450797618966,2.8406681128013975,2.513161047727077,1.7472293962722831,-0.24503774966773847,1.5590710612555858,0.43020921375824495,2.3418704683845455,0.358212818135691,0.3943400351131716,2.350148936285125,0.09772985746096338,0.5246297166579437,2.18215929435381,1.3540507039260963,1.192300224783089,2.26679759515337,0.21103780546535914,1.9110956664873515,1.0465360280824727,1.0465360280824727 | 3,053 |
Lipid transporter activity | 8 | 20 | 3.188521 | 0.00143 | O15118,Q9NV96,P04114,Q14849,P11166,Q4KMQ2,Q9H2C2,P17900 | Functions | GO Molecular function | msigdb_gomf | 164,106,144,49,243,244,87,88 | 581,164,144,1057,243,88,1352,878,855,261,737,2976,49,244,1953,871,1472,1247,87,106 | 0.6287863334786191,1.9557428487590485,2.0788303063459717,0.09772985746096338,1.6445651501196628,2.3749098883187894,-0.09708761132484221,0.23587033191152165,0.26057972136771734,1.5494862574126163,0.3823265059229414,-1.3979595289673528,2.6480472532459483,1.6445651501196628,-0.3695251711327288,0.2482403330382631,-0.15037063254699395,-0.03128805197937675,2.3831388606343356,2.2835694069887835 | 3,053 |
Transport of small molecules | 57 | 150 | 3.187145 | 0.001437 | P61289,Q9UNS2,Q96QD8,P61916,P55011,P09601,P45880,Q70HW3,Q8N4V1,P05023,P51798,P05141,Q9Y6M7,P04114,Q9C0H2,P04920,P21796,Q15043,Q9BUN8,P07237,Q96PU5,Q8NEW0,P30519,O15118,P02786,P40855,P49721,P98155,Q93050,P60900,P14672,Q8IYU8,Q9HD20,Q9Y6B6,Q9BPX6,P01130,P10644,Q8TB61,P08195,P38571,P16615,Q04656,P30825,Q15904,Q92581,P35613,P12235,Q8WTV0,P12236,Q9Y487,Q9UBX3,P51790,P11166,Q4KMQ2,Q9Y277,O95202,P36543 | Processes and pathways | Reactome Pathways | msigdb_reactome | 385,388,259,261,390,133,135,266,267,394,269,395,403,144,19,275,151,407,282,405,287,32,162,164,36,291,294,40,171,302,301,435,182,313,447,188,191,68,328,329,202,203,79,209,214,229,100,359,103,360,113,239,243,244,251,249,381 | 984,2782,508,2424,2833,164,1501,2177,2753,1810,2643,1185,2369,249,1451,188,36,144,275,394,395,1168,405,1057,328,1059,133,191,243,100,103,1942,301,202,548,1566,440,719,1171,1428,2735,2237,151,2593,2648,1353,2736,2942,2896,2262,782,878,162,2649,79,2518,553,1509,229,2711,714,381,329,2107,291,2737,135,2634,2820,294,1258,239,269,946,819,480,390,2670,1487,302,385,604,261,1260,1818,2409,1761,699,40,2380,2213,203,2547,951,1040,1381,1101,909,1857,1546,1669,407,613,209,244,2413,1953,266,2763,435,267,1902,1340,32,68,359,214,1218,171,636,287,259,1675,507,2225,926,823,713,447,872,282,19,731,1067,182,3035,765,679,113,1741,1873,927,1446,2278,388,251,360,1278,313,403 | 0.14840860507849105,-0.9497453913983102,0.7755641462351951,-0.6285741297543339,-1.0295533285196867,1.9557428487590485,-0.17723144136555438,-0.49730329369665177,-0.9181987971791161,-0.31380251320317754,-0.7940850336780507,-0.005212952459059928,-0.5990899607250865,1.625684832355376,-0.15037063254699395,1.866075878935031,2.779747026833827,2.0788303063459717,1.4721773650526246,1.0570844850930035,1.0570844850930035,0.007772986263866033,1.0359660555856258,0.09772985746096338,1.2433861353171847,0.09772985746096338,2.1479335171777034,1.8479620607680682,1.6445651501196628,2.308631386581677,2.291936121589696,-0.3695251711327288,1.3440861679024063,1.7932515087502272,0.685740711671661,-0.20424086935988572,0.9398515677513489,0.40632489423308854,0.007772986263866033,-0.13699538899316593,-0.8868625525092045,-0.5261652660770593,2.0439466216934568,-0.7483704240161151,-0.7940850336780507,-0.09708761132484221,-0.8868625525092045,-1.2605731068481651,-1.1271584702084125,-0.5406616335135016,0.33398257941175047,0.23587033191152165,1.9734989342155895,-0.7940850336780507,2.432256446318069,-0.688095106410563,0.674400725375824,-0.17723144136555438,1.6914754779087535,-0.8557335336316402,0.4182812364739646,1.088601740735695,1.2433861353171847,-0.45433286929698796,1.3838315350081463,-0.8868625525092045,2.1393434129981372,-0.7787977391346896,-0.9974667036146205,1.373923307859532,-0.044377623849349325,1.6633788128540579,1.5109728694831275,0.17355509404966507,0.2974158983461496,0.8419112349230434,1.0676115247162676,-0.8094218959475288,-0.16378257437491706,1.3440861679024063,1.0781172443576843,0.5943047502828036,1.5494862574126163,-0.044377623849349325,-0.31380251320317754,-0.613809285254711,-0.2861796454358755,0.44210897675379346,2.7181568448827473,-0.5990899607250865,-0.511712584314456,1.7840786381977862,-0.7030923807336273,0.17355509404966507,0.11044822745697883,-0.1103540999259057,0.059377376010689153,0.21103780546535914,-0.32767317867730517,-0.19071746259586272,-0.24503774966773847,1.0359660555856258,0.5827586084337831,1.765685690904278,1.6445651501196628,-0.613809285254711,-0.3695251711327288,1.5206274845608097,-0.9181987971791161,0.9613654253667215,1.5206274845608097,-0.34158367124160455,-0.08385693476833972,2.8406681128013975,2.513161047727077,1.1510683617802193,1.7472293962722831,-0.018233230344920522,1.937928245362595,0.5479614575971996,1.4035922338561988,1.5590710612555858,-0.24503774966773847,0.7866818484921456,-0.511712584314456,0.19857493350037805,0.2974158983461496,0.43020921375824495,0.9398515677513489,0.2482403330382631,1.433095060674533,3.0342313533271863,0.3943400351131716,0.09772985746096338,1.9021217402473265,-3.1749041769284885,0.358212818135691,0.477640468160584,2.26679759515337,-0.27242694039497706,-0.32767317867730517,0.19857493350037805,-0.13699538899316593,-0.5406616335135016,1.0781172443576843,1.625684832355376,1.1510683617802193,-0.044377623849349325,1.3040379142045533,1.0465360280824727 | 3,053 |
Vesicle organization | 35 | 91 | 3.18358 | 0.001455 | Q6IAA8,Q13501,O60499,Q5SQN1,P62820,Q9BTU6,Q13277,Q9NR31,P61020,Q9H4A5,O15400,O00560,P14672,Q9Y6B6,Q9UNK0,Q9P0T7,Q9H9H4,Q9BZG1,Q99523,Q14964,Q14108,Q9HCU5,Q92692,P49755,O95249,Q13190,P51809,Q8WUM4,P51790,P08754,Q15363,Q86Y82,P51149,Q96CW1,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 386,4,8,528,398,276,154,284,166,167,169,168,301,313,319,64,450,579,77,465,213,470,473,603,224,225,353,616,239,623,374,246,502,636,254 | 1325,1229,168,662,1476,1326,169,640,1533,1596,1232,8,1879,1656,943,2100,790,1598,224,1233,1450,2590,2985,2707,623,301,1352,254,2046,1060,603,502,1149,239,353,1410,2455,3018,166,1541,398,225,154,1576,4,2026,213,465,1011,374,1605,972,528,386,1491,246,922,616,2441,1297,473,1121,860,636,2330,77,849,276,1065,2227,579,1935,167,450,470,1274,284,3032,1680,2277,64,1714,1966,2572,1621,2128,319,1003,789,852,313 | -0.08385693476833972,-0.03128805197937675,1.937928245362595,0.501189764703237,-0.16378257437491706,-0.08385693476833972,1.937928245362595,0.5363090433704797,-0.19071746259586272,-0.21780189519795196,-0.03128805197937675,3.3336104827050863,-0.34158367124160455,-0.24503774966773847,0.17355509404966507,-0.45433286929698796,0.3218233565713564,-0.21780189519795196,1.7008082712982846,-0.03128805197937675,-0.15037063254699395,-0.7483704240161151,-1.5037706134431923,-0.8557335336316402,0.5595870981994009,1.3440861679024063,-0.09708761132484221,1.5877220944504011,-0.42589761215042704,0.09772985746096338,0.5943047502828036,0.7866818484921456,0.020724788531935035,1.6633788128540579,1.1717250589049941,-0.12365661898489545,-0.6433848115667744,-2.033200490824227,1.9557428487590485,-0.19071746259586272,1.0465360280824727,1.7008082712982846,2.0351905672615014,-0.20424086935988572,3.430024135370345,-0.41174265253282316,1.7472293962722831,0.8965525637862654,0.13578741527968066,1.1095074471795692,-0.21780189519795196,0.16099777070340407,0.7196100272359108,1.0781172443576843,-0.16378257437491706,1.635133356253012,0.19857493350037805,0.5827586084337831,-0.6285741297543339,-0.05750215436707501,0.8638375447218682,0.0465267852872829,0.26057972136771734,0.5479614575971996,-0.5697866191684537,2.4485323268593073,0.2728886665037662,1.4721773650526246,0.09772985746096338,-0.511712584314456,0.6402283550178628,-0.35553424861853866,1.9468428888650193,0.9290608874339265,0.8747656995030354,-0.044377623849349325,1.423279111691743,-3.0205793937440046,-0.24503774966773847,-0.5406616335135016,2.553174480013193,-0.2587130568814146,-0.3695251711327288,-0.7181371319149215,-0.21780189519795196,-0.45433286929698796,1.273799811880788,0.14840860507849105,0.33398257941175047,0.2728886665037662,1.3040379142045533 | 3,053 |
Golgi associated vesicle | 13 | 35 | 3.166475 | 0.001543 | O43731,O43493,P24390,Q9Y3B3,Q04656,Q99523,Q8N511,P14672,P11717,Q9Y287,Q8TCT8,Q8IUH4,P05067 | Localization | GO Cellular component | msigdb_gocc | 0,3,37,330,203,77,270,301,109,20,125,279,29 | 1716,3,0,1533,1451,29,1059,854,109,301,37,793,1600,603,1149,2864,2266,1541,1571,2213,968,203,374,279,270,125,1493,77,1065,726,814,1198,20,330,736 | -0.27242694039497706,3.585003342735257,3.7488958239943146,-0.19071746259586272,-0.15037063254699395,2.8859295440854202,0.09772985746096338,0.26057972136771734,2.26679759515337,1.3440861679024063,2.779747026833827,0.3218233565713564,-0.21780189519795196,0.5943047502828036,0.020724788531935035,-1.0618618334058418,-0.5406616335135016,-0.19071746259586272,-0.20424086935988572,-0.511712584314456,0.16099777070340407,1.7840786381977862,1.1095074471795692,1.4526723602880829,1.5109728694831275,2.1906823149730266,-0.16378257437491706,2.4485323268593073,0.09772985746096338,0.40632489423308854,0.30963451704569495,-0.005212952459059928,3.026907865726523,1.2433861353171847,0.3943400351131716 | 3,053 |
Secondary active transmembrane transporter activity | 13 | 25 | 3.158689 | 0.001585 | Q96QD8,P12235,P55011,P12236,P08195,P05141,P51798,Q9Y6M7,Q9UBX3,P51790,P04920,Q92581,O95202 | Functions | GO Molecular function | msigdb_gomf | 259,100,390,103,328,395,269,403,113,239,275,214,249 | 508,249,275,395,328,100,103,1207,239,269,720,819,390,1637,808,407,613,1340,214,1772,259,763,1067,113,403 | 0.7755641462351951,1.625684832355376,1.4721773650526246,1.0570844850930035,1.2433861353171847,2.308631386581677,2.291936121589696,-0.018233230344920522,1.6633788128540579,1.5109728694831275,0.40632489423308854,0.2974158983461496,1.0676115247162676,-0.2314007759263953,0.30963451704569495,1.0359660555856258,0.5827586084337831,-0.08385693476833972,1.7472293962722831,-0.2861796454358755,1.5590710612555858,0.358212818135691,0.09772985746096338,2.26679759515337,1.0465360280824727 | 3,053 |
Azurophil granule membrane | 12 | 22 | 3.149788 | 0.001634 | P51809,O00462,Q6IAA8,O15260,Q9NV96,Q92542,P07602,Q07065,P11279,Q9NQX7,P10253,Q9NZJ7 | Localization | GO Cellular component | msigdb_gocc | 353,97,386,227,106,206,21,309,121,59,93,351 | 97,227,1597,1782,1656,21,93,121,1693,555,406,353,309,386,576,206,2058,731,59,106,351,2277 | 2.316960023648094,1.6914754779087535,-0.21780189519795196,-0.299971419663726,-0.24503774966773847,3.0195749043603826,2.3418704683845455,2.2161719066574945,-0.2587130568814146,0.674400725375824,1.0359660555856258,1.1717250589049941,1.31407865704397,1.0781172443576843,0.6402283550178628,1.774890052445681,-0.42589761215042704,0.3943400351131716,2.584978865712065,2.2835694069887835,1.192300224783089,-0.5406616335135016 | 3,053 |
Host cell receptor for virus entry | 12 | 19 | 3.149165 | 0.001637 | Q9Y624,P11279,P06756,O15118,P02786,P35613,Q8WTV0,P00533,P15529,Q14108,Q92692,P01130 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 352,121,195,164,36,229,359,335,236,213,473,188 | 164,335,188,36,524,1372,195,1403,2179,121,2210,236,229,774,213,613,359,473,352 | 1.9557428487590485,1.2230116728735583,1.866075878935031,2.779747026833827,0.7308499991523034,-0.1103540999259057,1.8297870381814723,-0.12365661898489545,-0.49730329369665177,2.2161719066574945,-0.511712584314456,1.6633788128540579,1.6914754779087535,0.34611234668124813,1.7472293962722831,0.5827586084337831,1.1510683617802193,0.8638375447218682,1.192300224783089 | 3,053 |
Exogenous protein binding | 12 | 19 | 3.149165 | 0.001637 | Q9Y624,P11279,P06756,O15118,P02786,P35613,Q8WTV0,P00533,P15529,Q14108,Q92692,P01130 | Functions | GO Molecular function | msigdb_gomf | 352,121,195,164,36,229,359,335,236,213,473,188 | 164,335,188,36,524,1372,195,1403,2179,121,2210,236,229,774,213,613,359,473,352 | 1.9557428487590485,1.2230116728735583,1.866075878935031,2.779747026833827,0.7308499991523034,-0.1103540999259057,1.8297870381814723,-0.12365661898489545,-0.49730329369665177,2.2161719066574945,-0.511712584314456,1.6633788128540579,1.6914754779087535,0.34611234668124813,1.7472293962722831,0.5827586084337831,1.1510683617802193,0.8638375447218682,1.192300224783089 | 3,053 |
Establishment of protein localization to membrane | 24 | 80 | 3.142694 | 0.001674 | Q9NS69,Q8N4V1,Q15070,Q9Y512,O60725,Q9P0J0,Q99442,Q13277,Q96A33,O15118,P40855,P43307,Q9H4A5,O00560,P0DP25,Q9HD20,Q53H12,Q9H9H4,Q15042,P00533,Q15904,Q15629,P51149,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 1,267,16,531,272,400,535,154,285,164,291,38,167,168,311,182,571,450,326,335,209,217,502,254 | 1744,1229,168,1072,1326,164,1747,1595,1369,272,2885,1115,1423,1081,335,1921,1535,311,1999,2373,254,2315,2136,291,2374,38,1432,1036,1020,783,502,1696,2964,2138,795,948,1820,918,1821,1979,1488,154,1358,1766,326,16,217,209,635,571,2638,922,2297,267,910,1295,285,1299,535,579,937,167,2391,450,182,726,1024,1,1871,400,900,1182,1200,1052,940,1937,2038,1915,531,769 | -0.2861796454358755,-0.03128805197937675,1.937928245362595,0.0849787193065716,-0.08385693476833972,1.9557428487590485,-0.2861796454358755,-0.21780189519795196,-0.1103540999259057,1.501300622699395,-1.1107482414651932,0.0465267852872829,-0.13699538899316593,0.0721946227962857,1.2230116728735583,-0.35553424861853866,-0.19071746259586272,1.3040379142045533,-0.3976291060973344,-0.5990899607250865,1.5877220944504011,-0.5697866191684537,-0.4686137231142239,1.3838315350081463,-0.5990899607250865,2.749036603520299,-0.13699538899316593,0.11044822745697883,0.1231340177911712,0.33398257941175047,0.7866818484921456,-0.2587130568814146,-1.3459573008332442,-0.4686137231142239,0.3218233565713564,0.17355509404966507,-0.31380251320317754,0.19857493350037805,-0.31380251320317754,-0.38355670174670764,-0.16378257437491706,2.0351905672615014,-0.09708761132484221,-0.2861796454358755,1.2535436771356345,3.070707640988607,1.737977340170717,1.765685690904278,0.5479614575971996,0.6516446748258692,-0.7787977391346896,0.19857493350037805,-0.5552019842727006,1.5206274845608097,0.21103780546535914,-0.05750215436707501,1.4134448616858115,-0.05750215436707501,0.7083452377706503,0.6402283550178628,0.18608075541134228,1.9468428888650193,-0.5990899607250865,0.9290608874339265,1.9021217402473265,0.40632489423308854,0.1231340177911712,3.6708025762594803,-0.32767317867730517,1.0465360280824727,0.22346954691003423,0.007772986263866033,-0.005212952459059928,0.11044822745697883,0.18608075541134228,-0.35553424861853866,-0.41174265253282316,-0.34158367124160455,0.7196100272359108,0.358212818135691 | 3,053 |
Recycling endosome | 20 | 35 | 3.139638 | 0.001692 | P05556,O15127,P05067,P02786,P10321,O15400,Q92673,Q969E2,Q9UID3,Q9UNK0,P01889,Q96A57,Q92581,Q9H223,P04439,P51790,O14773,O14828,Q86Y82,Q9H4M9 | Localization | GO Cellular component | msigdb_gocc | 524,147,29,36,165,169,54,444,573,319,325,204,214,357,105,239,108,369,246,377 | 108,369,582,147,169,1533,325,36,105,29,524,165,1972,1149,239,795,1541,1662,1100,1208,1191,776,2986,246,214,54,444,204,357,1935,377,573,1529,319,1203 | 2.26679759515337,1.1095074471795692,0.6287863334786191,2.070130363883016,1.937928245362595,-0.19071746259586272,1.2535436771356345,2.779747026833827,2.2835694069887835,2.8859295440854202,0.7308499991523034,1.9557428487590485,-0.38355670174670764,0.020724788531935035,1.6633788128540579,0.3218233565713564,-0.19071746259586272,-0.24503774966773847,0.059377376010689153,-0.018233230344920522,-0.005212952459059928,0.34611234668124813,-1.5037706134431923,1.635133356253012,1.7472293962722831,2.616602358730607,0.9398515677513489,1.7840786381977862,1.1614069470810378,-0.35553424861853866,1.099065109888305,0.6516446748258692,-0.17723144136555438,1.273799811880788,-0.005212952459059928 | 3,053 |
Transporter | 62 | 186 | 3.134963 | 0.001719 | O43731,Q9HC07,O43493,Q96QD8,P55011,O60499,Q9P2W9,Q70HW3,P05023,P05141,Q9Y6M7,Q9Y6C9,Q15070,P04920,Q15043,Q99805,Q13277,Q8NEW0,Q15012,P24390,Q93050,Q9HD45,O15400,O00560,Q9HC21,P14672,Q9Y619,Q92673,Q9UNK0,Q92544,Q8TB61,P08195,P16615,Q04656,Q9Y3B3,Q99523,Q6NUK1,P30825,Q7L0J3,Q92973,Q92581,P17900,Q9H2D1,Q9BSK2,O95249,Q13190,Q9NZJ7,P51809,P12235,P54105,P12236,Q9Y487,O43760,Q03518,Q9UBX3,Q8NFH4,Q15363,P11166,Q86Y82,P11279,O95202,Q9BQE5 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 0,128,3,259,390,8,136,266,394,395,403,402,16,275,407,26,154,32,35,37,171,172,169,168,299,301,180,54,319,323,68,328,202,203,330,77,332,79,80,343,214,88,92,95,224,225,351,353,100,354,103,360,358,234,113,365,374,243,246,121,249,127 | 1325,680,1229,508,2750,1594,168,2895,1716,1476,581,169,3,0,358,3007,538,8,2869,941,942,1879,2177,1750,2401,1095,1598,249,224,1233,1450,2590,519,275,394,395,1687,1057,328,1059,854,243,121,100,103,301,202,88,440,1428,2735,37,1148,2946,878,1813,79,793,1510,1538,2107,1207,1600,855,697,603,783,644,353,818,1695,720,2864,2266,946,819,2455,354,480,663,390,598,1009,2188,604,948,1571,1761,737,1637,2213,775,808,234,203,728,710,625,225,154,1576,1382,953,1210,35,407,16,1011,374,690,613,528,3005,332,1953,266,80,1135,883,246,492,674,32,365,68,1179,572,2441,1493,323,420,214,54,343,171,869,760,1438,1772,1674,259,1299,2465,77,847,26,713,127,2912,95,1065,763,801,731,1935,92,2852,1067,652,128,299,172,2229,351,1680,2277,1714,136,1198,2095,113,1873,2694,913,319,1111,653,2145,1017,330,360,1112,180,736,402,403 | -0.08385693476833972,0.4658244563610143,-0.03128805197937675,0.7755641462351951,-0.9181987971791161,-0.21780189519795196,1.937928245362595,-1.1271584702084125,-0.27242694039497706,-0.16378257437491706,0.6287863334786191,1.937928245362595,3.585003342735257,3.7488958239943146,1.1510683617802193,-1.7418453203119433,0.6970555073651654,3.3336104827050863,-1.0781003736110784,0.17355509404966507,0.17355509404966507,-0.34158367124160455,-0.49730329369665177,-0.2861796454358755,-0.613809285254711,0.059377376010689153,-0.21780189519795196,1.625684832355376,1.7008082712982846,-0.03128805197937675,-0.15037063254699395,-0.7483704240161151,0.7420652759647238,1.4721773650526246,1.0570844850930035,1.0570844850930035,-0.2587130568814146,0.09772985746096338,1.2433861353171847,0.09772985746096338,0.26057972136771734,1.6445651501196628,2.2161719066574945,2.308631386581677,2.291936121589696,1.3440861679024063,1.7932515087502272,2.3749098883187894,0.9398515677513489,-0.13699538899316593,-0.8868625525092045,2.779747026833827,0.020724788531935035,-1.277523820402273,0.23587033191152165,-0.31380251320317754,2.432256446318069,0.3218233565713564,-0.17723144136555438,-0.19071746259586272,-0.45433286929698796,-0.018233230344920522,-0.21780189519795196,0.26057972136771734,0.44210897675379346,0.5943047502828036,0.33398257941175047,0.5246297166579437,1.1717250589049941,0.2974158983461496,-0.2587130568814146,0.40632489423308854,-1.0618618334058418,-0.5406616335135016,0.17355509404966507,0.2974158983461496,-0.6433848115667744,1.1717250589049941,0.8419112349230434,0.501189764703237,1.0676115247162676,0.6058246629645279,0.13578741527968066,-0.49730329369665177,0.5943047502828036,0.17355509404966507,-0.20424086935988572,-0.2861796454358755,0.3823265059229414,-0.2314007759263953,-0.511712584314456,0.34611234668124813,0.30963451704569495,1.6727608132509426,1.7840786381977862,0.3943400351131716,0.43020921375824495,0.5595870981994009,1.7008082712982846,2.0351905672615014,-0.20424086935988572,-0.1103540999259057,0.17355509404966507,-0.018233230344920522,2.8026699653933203,1.0359660555856258,3.070707640988607,0.13578741527968066,1.1095074471795692,0.4539806748878796,0.5827586084337831,0.7196100272359108,-1.6857818609693211,1.2332088294189667,-0.3695251711327288,1.5206274845608097,2.432256446318069,0.03364265519892447,0.23587033191152165,1.635133356253012,0.8088450797618966,0.477640468160584,2.8406681128013975,1.1303294043028353,2.513161047727077,0.007772986263866033,0.6516446748258692,-0.6285741297543339,-0.16378257437491706,1.2636815408562456,1.0041260536406191,1.7472293962722831,2.616602358730607,1.2127945785226133,1.937928245362595,0.2482403330382631,0.358212818135691,-0.13699538899316593,-0.2861796454358755,-0.24503774966773847,1.5590710612555858,-0.05750215436707501,-0.6433848115667744,2.4485323268593073,0.2728886665037662,2.9382790868184965,0.43020921375824495,2.18215929435381,-1.1601538119786206,2.3418704683845455,0.09772985746096338,0.358212818135691,0.3218233565713564,0.3943400351131716,-0.35553424861853866,2.350148936285125,-1.0456796307190568,0.09772985746096338,0.5246297166579437,2.18215929435381,1.3540507039260963,1.937928245362595,-0.511712584314456,1.192300224783089,-0.24503774966773847,-0.5406616335135016,-0.2587130568814146,2.1393434129981372,-0.005212952459059928,-0.4400942588347924,2.26679759515337,-0.32767317867730517,-0.824808688320819,0.21103780546535914,1.273799811880788,0.059377376010689153,0.5246297166579437,-0.4686137231142239,0.13578741527968066,1.2433861353171847,1.1510683617802193,0.059377376010689153,1.9110956664873515,0.3943400351131716,1.0465360280824727,1.0465360280824727 | 3,053 |
Gated channel activity | 8 | 15 | 3.122418 | 0.001794 | Q9H813,P06756,P45880,P51790,Q9C0H2,Q4KMQ2,P21796,Q9Y277 | Functions | GO Molecular function | msigdb_gomf | 89,195,135,239,19,244,151,251 | 2589,195,1752,1096,151,135,239,269,918,244,1613,19,89,765,251 | -0.7483704240161151,1.8297870381814723,-0.2861796454358755,0.059377376010689153,2.0439466216934568,2.1393434129981372,1.6633788128540579,1.5109728694831275,0.19857493350037805,1.6445651501196628,-0.21780189519795196,3.0342313533271863,2.3749098883187894,0.358212818135691,1.625684832355376 | 3,053 |
Transport vesicle membrane | 26 | 45 | 3.11293 | 0.001852 | P20339,O60499,P62820,Q9NR31,P10321,P61020,Q92673,P0DP25,Q9Y6B6,P19021,P20020,P01889,P16870,O15126,Q9Y3B3,Q7L0J3,P49755,Q13190,P51809,O43760,P04439,Q9NV96,O76024,Q15363,Q86Y82,P51149 | Localization | GO Cellular component | msigdb_gocc | 514,8,398,284,165,166,54,311,313,63,440,325,70,582,330,80,603,225,353,358,105,106,372,374,246,502 | 622,1326,582,1533,358,8,1879,943,790,372,1598,1450,2590,1451,325,105,1059,854,311,165,70,63,440,514,697,603,502,353,2455,166,398,2213,225,776,374,1605,80,246,54,284,106,2572,330,313,1251 | 0.5595870981994009,-0.08385693476833972,0.6287863334786191,-0.19071746259586272,1.1510683617802193,3.3336104827050863,-0.34158367124160455,0.17355509404966507,0.3218233565713564,1.1095074471795692,-0.21780189519795196,-0.15037063254699395,-0.7483704240161151,-0.15037063254699395,1.2535436771356345,2.2835694069887835,0.09772985746096338,0.26057972136771734,1.3040379142045533,1.9557428487590485,2.480941024337575,2.5690994296216365,0.9398515677513489,0.7644222293835908,0.44210897675379346,0.5943047502828036,0.7866818484921456,1.1717250589049941,-0.6433848115667744,1.9557428487590485,1.0465360280824727,-0.511712584314456,1.7008082712982846,0.34611234668124813,1.1095074471795692,-0.21780189519795196,2.432256446318069,1.635133356253012,2.616602358730607,1.423279111691743,2.2835694069887835,-0.7181371319149215,1.2433861353171847,1.3040379142045533,-0.03128805197937675 | 3,053 |
Immunoglobulin-like domain [IPR007110] | 11 | 16 | 3.110195 | 0.00187 | Q9Y624,P35613,P01889,P10321,P10586,P04439,Q08722,Q7KYR7,P43121,Q96J84,Q5ZPR3 | Sequence | InterPro Domain | interpro_domain | 352,229,325,165,230,105,140,364,238,248,157 | 325,105,165,230,229,238,774,140,626,1190,157,364,1013,473,248,352 | 1.2535436771356345,2.2835694069887835,1.9557428487590485,1.6821263466818883,1.6914754779087535,1.6633788128540579,0.34611234668124813,2.1048469198732267,0.5595870981994009,-0.005212952459059928,2.0088372660094183,1.1303294043028353,0.13578741527968066,0.8638375447218682,1.635133356253012,1.192300224783089 | 3,053 |
Immunoglobulin-like domain superfamily [IPR036179] | 11 | 16 | 3.110195 | 0.00187 | Q9Y624,P35613,P01889,P10321,P10586,P04439,Q08722,Q7KYR7,P43121,Q96J84,Q5ZPR3 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 352,229,325,165,230,105,140,364,238,248,157 | 325,105,165,230,229,238,774,140,626,1190,157,364,1013,473,248,352 | 1.2535436771356345,2.2835694069887835,1.9557428487590485,1.6821263466818883,1.6914754779087535,1.6633788128540579,0.34611234668124813,2.1048469198732267,0.5595870981994009,-0.005212952459059928,2.0088372660094183,1.1303294043028353,0.13578741527968066,0.8638375447218682,1.635133356253012,1.192300224783089 | 3,053 |
Ion transport | 29 | 52 | 3.10602 | 0.001896 | Q96QD8,P55011,O75964,P45880,P05023,P51798,Q9Y6M7,P04920,Q9C0H2,P21796,Q15043,Q8NEW0,Q93050,Q9BPX6,P20020,Q9H0H5,P16615,Q04656,Q15904,Q8NE01,Q92581,Q9H813,P54709,Q9Y487,P51790,Q4KMQ2,Q9Y277,O95202,P36543 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 259,390,260,135,394,269,403,275,19,151,407,32,171,447,440,324,202,203,209,210,214,89,480,360,239,244,251,249,381 | 2589,1095,260,249,519,275,394,1687,1096,202,440,1428,2735,151,1148,2946,1510,381,2107,135,2954,239,269,480,390,598,1009,604,203,1338,407,209,244,3005,2413,210,1340,32,214,171,259,675,447,1613,19,324,89,1873,1069,251,360,403 | -0.7483704240161151,0.059377376010689153,1.5494862574126163,1.625684832355376,0.7420652759647238,1.4721773650526246,1.0570844850930035,-0.2587130568814146,0.059377376010689153,1.7932515087502272,0.9398515677513489,-0.13699538899316593,-0.8868625525092045,2.0439466216934568,0.020724788531935035,-1.277523820402273,-0.17723144136555438,1.088601740735695,-0.45433286929698796,2.1393434129981372,-1.3116133841257678,1.6633788128540579,1.5109728694831275,0.8419112349230434,1.0676115247162676,0.6058246629645279,0.13578741527968066,0.5943047502828036,1.7840786381977862,-0.08385693476833972,1.0359660555856258,1.765685690904278,1.6445651501196628,-1.6857818609693211,-0.613809285254711,1.765685690904278,-0.08385693476833972,2.8406681128013975,1.7472293962722831,1.937928245362595,1.5590710612555858,0.477640468160584,0.9398515677513489,-0.21780189519795196,3.0342313533271863,1.2636815408562456,2.3749098883187894,-0.32767317867730517,0.09772985746096338,1.625684832355376,1.1510683617802193,1.0465360280824727 | 3,053 |
Immunoglobulin-like fold [IPR013783] | 18 | 37 | 3.105217 | 0.001901 | Q9Y624,O00462,Q15375,O15031,P35613,P10321,P01889,P10586,Q96J84,P04439,Q08722,P43121,P08236,P15260,Q92673,Q8IZA0,Q14596,Q5ZPR3 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 352,97,34,98,229,165,325,230,248,105,140,238,241,22,54,56,91,157 | 97,98,1994,2797,1233,325,105,552,241,165,230,22,2818,229,238,2821,774,968,1949,140,626,1190,2270,91,34,157,364,1314,56,1013,54,473,248,1270,2277,2662,352 | 2.316960023648094,2.316960023648094,-0.3976291060973344,-0.965598565884847,-0.03128805197937675,1.2535436771356345,2.2835694069887835,0.674400725375824,1.6539802803309698,1.9557428487590485,1.6821263466818883,3.004880449945332,-0.9974667036146205,1.6914754779087535,1.6633788128540579,-0.9974667036146205,0.34611234668124813,0.16099777070340407,-0.3695251711327288,2.1048469198732267,0.5595870981994009,-0.005212952459059928,-0.5406616335135016,2.350148936285125,2.810290185930751,2.0088372660094183,1.1303294043028353,-0.07066185389454786,2.5929016072601465,0.13578741527968066,2.616602358730607,0.8638375447218682,1.635133356253012,-0.044377623849349325,-0.5406616335135016,-0.7940850336780507,1.192300224783089 | 3,053 |
Loss of speech | 7 | 19 | 3.104359 | 0.001907 | O15118,P61916,Q13501,P50897,P07602,O00754,P17900 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 164,261,4,53,21,181,88 | 181,164,1595,1784,1185,21,88,53,2265,1099,1487,1853,261,4,2499,1894,351,1003,2342 | 1.9021217402473265,1.9557428487590485,-0.21780189519795196,-0.299971419663726,-0.005212952459059928,3.0195749043603826,2.3749098883187894,2.616602358730607,-0.5406616335135016,0.059377376010689153,-0.16378257437491706,-0.32767317867730517,1.5494862574126163,3.430024135370345,-0.6731449738170256,-0.34158367124160455,1.192300224783089,0.14840860507849105,-0.5697866191684537 | 3,053 |
Organophosphate ester transport | 14 | 28 | 3.097227 | 0.001953 | P61916,Q8TB61,P12235,Q8WTV0,P12236,Q9NV96,Q08722,Q9HC21,Q6NUK1,Q9H2D1,Q4KMQ2,Q14108,P01130,Q9BSK2 | Processes and pathways | GO Biological process | msigdb_gobp | 261,68,100,359,103,106,140,299,332,92,244,213,188,95 | 508,538,188,395,1057,100,103,1352,2429,1207,855,261,737,2190,140,213,244,2413,332,68,359,713,95,1247,92,299,106,2277 | 0.7755641462351951,0.6970555073651654,1.866075878935031,1.0570844850930035,0.09772985746096338,2.308631386581677,2.291936121589696,-0.09708761132484221,-0.6285741297543339,-0.018233230344920522,0.26057972136771734,1.5494862574126163,0.3823265059229414,-0.49730329369665177,2.1048469198732267,1.7472293962722831,1.6445651501196628,-0.613809285254711,1.2332088294189667,2.513161047727077,1.1510683617802193,0.43020921375824495,2.3418704683845455,-0.03128805197937675,2.350148936285125,1.3540507039260963,2.2835694069887835,-0.5406616335135016 | 3,053 |
Glycosphingolipid metabolic process | 9 | 12 | 3.095432 | 0.001965 | P16278,P06865,P06280,Q8TCT0,P07686,Q99519,Q16739,P17900,Q99805 | Processes and pathways | GO Biological process | msigdb_gobp | 73,72,45,205,208,148,119,88,26 | 288,45,72,208,73,88,2190,1979,119,205,148,26 | 1.3937211509001355,2.6715150735890525,2.4728566349196144,1.765685690904278,2.4728566349196144,2.3749098883187894,-0.49730329369665177,-0.38355670174670764,2.224642100818324,1.774890052445681,2.070130363883016,2.9382790868184965 | 3,053 |
Endosome | 83 | 218 | 3.079615 | 0.002073 | O43493,Q13501,Q8IV08,Q9Y287,P07602,Q99805,P07858,P05067,Q15012,P02786,Q14849,Q9BXS4,Q92673,Q9P0T7,Q06481,Q99523,Q14596,P42892,P04439,Q9NV96,P11717,Q07954,O14773,P11279,O00461,O95772,Q8TCT8,Q9HC07,Q9UIQ6,Q9BRK5,P04114,O15127,O15118,P10321,P61020,Q93050,O15400,P01130,P10644,P98164,Q99538,Q04656,Q96A57,Q92542,Q15904,Q14108,Q92581,P35613,P51790,Q86Y82,P31751,Q8N4V1,Q9BTU6,Q96J02,Q9BUN8,Q96PU5,P14672,P20645,Q13510,Q9UNK0,Q92544,O75787,P01889,P00533,Q9NZJ7,P51809,Q9H223,Q9Y487,O75955,O14828,Q9H4M9,P36543,Q6IAA8,Q969Q5,P62820,Q9NX40,Q15043,P51148,O14786,Q14254,Q969E2,Q9H9H4,Q7Z6M1 | Localization | GO Cellular component | msigdb_gocc | 3,4,14,20,21,26,27,29,35,36,49,50,54,64,74,77,91,101,105,106,109,110,108,121,120,124,125,128,137,142,144,147,164,165,166,171,169,188,191,196,201,203,204,206,209,213,214,229,239,246,254,267,276,281,282,287,301,312,318,319,323,320,325,335,351,353,357,360,363,369,377,381,386,399,398,411,407,406,412,432,444,450,455 | 914,120,1476,108,412,369,164,582,147,1113,169,916,561,2510,3,640,1533,1281,1232,2869,942,1597,617,540,1656,943,2100,1750,320,363,2402,2369,665,124,1451,335,188,325,36,2985,144,105,29,524,2707,21,27,1752,1754,1059,165,191,2914,1922,121,109,1283,301,2182,781,514,312,2632,1481,2105,1944,1507,2901,1972,989,2574,2990,254,2518,229,381,2046,1207,1409,101,966,406,502,542,1149,239,353,946,166,795,1541,604,1457,1662,398,1100,1287,1208,1761,196,2213,968,1152,203,2190,74,110,2318,1087,1576,4,318,1101,1382,2497,213,432,91,1154,2689,49,2053,35,656,407,1191,776,1011,1360,209,2745,2986,724,1578,386,1549,1491,455,246,657,1956,14,601,267,125,616,2441,206,323,214,54,860,171,444,399,204,760,636,2330,281,527,287,1299,871,77,201,26,849,2088,142,276,282,3051,1645,762,1472,50,357,1935,377,450,128,1274,468,1616,2229,106,3032,411,351,1680,64,1714,1318,1966,1164,632,2095,1165,573,137,1302,1052,980,981,1621,2128,1529,1419,319,1003,20,1203,1368,789,360,1397,1324 | 0.19857493350037805,2.2161719066574945,-0.16378257437491706,2.26679759515337,1.025374468803066,1.1095074471795692,1.9557428487590485,0.6287863334786191,2.070130363883016,0.0465267852872829,1.937928245362595,0.19857493350037805,0.6630354221866084,-0.688095106410563,3.585003342735257,0.5363090433704797,-0.19071746259586272,-0.05750215436707501,-0.03128805197937675,-1.0781003736110784,0.17355509404966507,-0.21780189519795196,0.571186102927646,0.6970555073651654,-0.24503774966773847,0.17355509404966507,-0.45433286929698796,-0.2861796454358755,1.2636815408562456,1.1303294043028353,-0.613809285254711,-0.5990899607250865,0.4894288560742516,2.1906823149730266,-0.15037063254699395,1.2230116728735583,1.866075878935031,1.2535436771356345,2.779747026833827,-1.5037706134431923,2.0788303063459717,2.2835694069887835,2.8859295440854202,0.7308499991523034,-0.8557335336316402,3.0195749043603826,2.9233715788819468,-0.2861796454358755,-0.2861796454358755,0.09772985746096338,1.9557428487590485,1.8479620607680682,-1.1767398600294696,-0.35553424861853866,2.2161719066574945,2.26679759515337,-0.05750215436707501,1.3440861679024063,-0.49730329369665177,0.33398257941175047,0.7644222293835908,1.3040379142045533,-0.7787977391346896,-0.16378257437491706,-0.45433286929698796,-0.3695251711327288,-0.17723144136555438,-1.1436268388419184,-0.38355670174670764,0.14840860507849105,-0.7332296988017242,-1.5576113434752126,1.5877220944504011,-0.688095106410563,1.6914754779087535,1.088601740735695,-0.42589761215042704,-0.018233230344920522,-0.12365661898489545,2.300290100303094,0.16099777070340407,1.0359660555856258,0.7866818484921456,0.6970555073651654,0.020724788531935035,1.6633788128540579,1.1717250589049941,0.17355509404966507,1.9557428487590485,0.3218233565713564,-0.19071746259586272,0.5943047502828036,-0.15037063254699395,-0.24503774966773847,1.0465360280824727,0.059377376010689153,-0.05750215436707501,-0.018233230344920522,-0.2861796454358755,1.8297870381814723,-0.511712584314456,0.16099777070340407,0.020724788531935035,1.7840786381977862,-0.49730329369665177,2.4566523252294235,2.26679759515337,-0.5697866191684537,0.0721946227962857,-0.20424086935988572,3.430024135370345,1.273799811880788,0.059377376010689153,-0.1103540999259057,-0.6731449738170256,1.7472293962722831,0.9613654253667215,2.350148936285125,0.020724788531935035,-0.824808688320819,2.6480472532459483,-0.42589761215042704,2.8026699653933203,0.512923337475363,1.0359660555856258,-0.005212952459059928,0.34611234668124813,0.13578741527968066,-0.09708761132484221,1.765685690904278,-0.9025045780882558,-1.5037706134431923,0.40632489423308854,-0.20424086935988572,1.0781172443576843,-0.19071746259586272,-0.16378257437491706,0.9182475647792882,1.635133356253012,0.512923337475363,-0.3695251711327288,3.135780580137371,0.6058246629645279,1.5206274845608097,2.1906823149730266,0.5827586084337831,-0.6285741297543339,1.774890052445681,1.2636815408562456,1.7472293962722831,2.616602358730607,0.26057972136771734,1.937928245362595,0.9398515677513489,1.0465360280824727,1.7840786381977862,0.358212818135691,0.5479614575971996,-0.5697866191684537,1.433095060674533,0.7308499991523034,1.4035922338561988,-0.05750215436707501,0.2482403330382631,2.4485323268593073,1.8024087243316227,2.9382790868184965,0.2728886665037662,-0.4400942588347924,2.096188534692145,1.4721773650526246,1.433095060674533,-7.272054429897521,-0.2314007759263953,0.358212818135691,-0.15037063254699395,2.6402026494641198,1.1614069470810378,-0.35553424861853866,1.099065109888305,0.9290608874339265,2.18215929435381,-0.044377623849349325,0.8856706691345428,-0.21780189519795196,-0.511712584314456,2.2835694069887835,-3.0205793937440046,1.0359660555856258,1.192300224783089,-0.24503774966773847,2.553174480013193,-0.2587130568814146,-0.07066185389454786,-0.3695251711327288,0.020724788531935035,0.5595870981994009,-0.4400942588347924,0.020724788531935035,0.6516446748258692,2.122122478433616,-0.05750215436707501,0.11044822745697883,0.16099777070340407,0.16099777070340407,-0.21780189519795196,-0.45433286929698796,-0.17723144136555438,-0.12365661898489545,1.273799811880788,0.14840860507849105,3.026907865726523,-0.005212952459059928,-0.09708761132484221,0.33398257941175047,1.1510683617802193,-0.1103540999259057,-0.07066185389454786 | 3,053 |
Exocytic vesicle | 21 | 38 | 3.072111 | 0.002126 | P20339,O60499,Q13277,P05067,P61020,O15400,P50897,P0DP25,P20020,O15126,Q96A57,Q92542,Q7L0J3,Q9BT78,P61421,O43760,P51790,O76024,Q86Y82,P11279,P51149 | Localization | GO Cellular component | msigdb_gocc | 514,8,154,29,166,169,53,311,440,582,204,206,80,218,604,358,239,372,246,121,502 | 622,582,169,358,1094,8,372,29,1059,854,311,121,440,514,1944,53,502,1149,239,166,795,604,154,1576,2497,2289,1264,776,1011,80,246,206,1181,204,218,1065,2229,2145 | 0.5595870981994009,0.6287863334786191,1.937928245362595,1.1510683617802193,0.059377376010689153,3.3336104827050863,1.1095074471795692,2.8859295440854202,0.09772985746096338,0.26057972136771734,1.3040379142045533,2.2161719066574945,0.9398515677513489,0.7644222293835908,-0.3695251711327288,2.616602358730607,0.7866818484921456,0.020724788531935035,1.6633788128540579,1.9557428487590485,0.3218233565713564,0.5943047502828036,2.0351905672615014,-0.20424086935988572,-0.6731449738170256,-0.5552019842727006,-0.044377623849349325,0.34611234668124813,0.13578741527968066,2.432256446318069,1.635133356253012,1.774890052445681,0.007772986263866033,1.7840786381977862,1.737977340170717,0.09772985746096338,-0.511712584314456,-0.4686137231142239 | 3,053 |
Membrane lipid catabolic process | 11 | 14 | 3.067972 | 0.002155 | P04062,P06865,P04066,P06280,P07686,O95470,Q99519,P50897,P17900,Q99735,Q13510 | Processes and pathways | GO Biological process | msigdb_gobp | 288,72,43,45,208,397,148,53,88,446,318 | 397,288,43,45,72,208,88,53,2190,318,443,148,446,959 | 1.0465360280824727,1.3937211509001355,2.702652806647846,2.6715150735890525,2.4728566349196144,1.765685690904278,2.3749098883187894,2.616602358730607,-0.49730329369665177,1.273799811880788,0.9398515677513489,2.070130363883016,0.9398515677513489,0.17355509404966507 | 3,053 |
Transmembrane transport | 98 | 211 | 3.06721 | 0.002161 | Q9NS69,L0R6Q1,O96008,P62942,O60830,P05556,O75915,Q9C0H2,Q99442,P05067,O60831,Q99595,Q8NEW0,O43808,P17612,Q8TB61,Q06481,O14678,Q07820,Q99523,P30825,Q7L0J3,P56134,Q9H2D1,Q9BSK2,P49755,P61421,O75381,P12235,P12236,Q9NV96,Q9UBX3,Q9HC07,O75844,Q16625,P45880,Q7KZN9,P21796,O14925,Q9Y619,Q9UDW1,Q9HD20,P06756,P98164,Q13423,P16615,Q04656,Q8NE01,Q92581,Q15629,Q9Y251,Q03518,Q9UHG3,P51790,P38435,P11166,Q4KMQ2,Q9Y277,O95202,P31751,P52789,Q96QD8,O75964,P39210,Q70HW3,Q8N4V1,P51798,P04920,Q8IUH4,Q96PU5,P04062,Q8NHS3,Q9HC21,P14672,O95831,P0DP25,Q6P4A7,P08195,Q6NUK1,P23786,Q8WTV0,P13073,P36543,P55011,P05023,P05141,Q9Y6M7,Q15526,Q15043,Q8IYU8,Q9BPX6,P20020,P03915,P00403,P54709,Q3ZCQ8,Q8IXU6,O00400 | Processes and pathways | GO Biological process | msigdb_gobp | 1,511,519,521,10,524,523,19,535,29,540,30,32,538,548,68,74,581,592,77,79,80,598,92,95,603,604,610,100,103,106,113,128,130,134,135,143,151,173,180,183,182,195,196,197,202,203,210,214,217,223,234,235,239,237,243,244,251,249,254,257,259,260,264,266,267,269,275,279,287,288,296,299,301,304,311,317,328,332,346,359,380,381,390,394,395,403,408,407,435,447,440,439,463,480,491,492,508 | 511,680,2589,508,1252,581,173,985,964,3007,538,2279,2617,10,540,2177,2399,2178,1502,610,2753,2401,130,523,1095,260,1423,249,304,519,463,439,288,275,394,29,395,524,1687,195,2707,2235,1374,1752,1057,328,755,1096,311,1628,2914,243,1350,100,103,380,301,202,548,440,1097,1428,2735,2818,151,346,1148,2946,1944,878,2106,2649,79,1568,254,2045,1128,3034,1510,381,237,2107,264,1207,1409,135,1256,2954,603,1257,783,966,239,269,257,720,819,1086,480,390,598,1009,2964,2138,604,948,1151,521,1119,196,1637,918,2976,808,234,203,1288,2192,74,2435,1979,592,2621,1488,197,1101,1462,1338,407,1011,690,408,217,613,134,2196,491,244,2413,332,1953,317,2956,1670,266,143,80,922,279,1901,492,435,1064,267,210,1340,32,296,68,2386,359,214,2201,1772,1439,1674,287,259,535,2994,77,30,926,823,713,447,1366,95,1613,763,1247,19,731,2944,92,1067,652,2276,128,299,182,726,1,106,765,113,183,900,1200,235,1873,913,927,1069,223,251,2533,1915,1278,180,403 | 0.7644222293835908,0.4658244563610143,-0.7483704240161151,0.7755641462351951,-0.044377623849349325,0.6287863334786191,1.9289988637379116,0.14840860507849105,0.16099777070340407,-1.7418453203119433,0.6970555073651654,-0.5552019842727006,-0.7635596540122364,3.2637394965616733,0.6970555073651654,-0.49730329369665177,-0.613809285254711,-0.49730329369665177,-0.17723144136555438,0.5827586084337831,-0.9181987971791161,-0.613809285254711,2.173622951248582,0.7308499991523034,0.059377376010689153,1.5494862574126163,-0.13699538899316593,1.625684832355376,1.334102702134965,0.7420652759647238,0.8965525637862654,0.9398515677513489,1.3937211509001355,1.4721773650526246,1.0570844850930035,2.8859295440854202,1.0570844850930035,0.7308499991523034,-0.2587130568814146,1.8297870381814723,-0.8557335336316402,-0.5261652660770593,-0.1103540999259057,-0.2861796454358755,0.09772985746096338,1.2433861353171847,0.358212818135691,0.059377376010689153,1.3040379142045533,-0.2314007759263953,-1.1767398600294696,1.6445651501196628,-0.09708761132484221,2.308631386581677,2.291936121589696,1.088601740735695,1.3440861679024063,1.7932515087502272,0.685740711671661,0.9398515677513489,0.059377376010689153,-0.13699538899316593,-0.8868625525092045,-0.9974667036146205,2.0439466216934568,1.2025574586113623,0.020724788531935035,-1.277523820402273,-0.3695251711327288,0.23587033191152165,-0.45433286929698796,-0.7940850336780507,2.432256446318069,-0.20424086935988572,1.5877220944504011,-0.42589761215042704,0.03364265519892447,-3.148782533062238,-0.17723144136555438,1.088601740735695,1.6633788128540579,-0.45433286929698796,1.5302645399456734,-0.018233230344920522,-0.12365661898489545,2.1393434129981372,-0.044377623849349325,-1.3116133841257678,0.5943047502828036,-0.044377623849349325,0.33398257941175047,0.16099777070340407,1.6633788128540579,1.5109728694831275,1.5686385889352172,0.40632489423308854,0.2974158983461496,0.0721946227962857,0.8419112349230434,1.0676115247162676,0.6058246629645279,0.13578741527968066,-1.3459573008332442,-0.4686137231142239,0.5943047502828036,0.17355509404966507,0.020724788531935035,0.7420652759647238,0.0465267852872829,1.8297870381814723,-0.2314007759263953,0.19857493350037805,-1.3979595289673528,0.30963451704569495,1.6727608132509426,1.7840786381977862,-0.05750215436707501,-0.49730329369665177,2.4566523252294235,-0.6285741297543339,-0.38355670174670764,0.6173184799051494,-0.7635596540122364,-0.16378257437491706,1.8206764297081328,0.059377376010689153,-0.15037063254699395,-0.08385693476833972,1.0359660555856258,0.13578741527968066,0.4539806748878796,1.0359660555856258,1.737977340170717,0.5827586084337831,2.1479335171777034,-0.49730329369665177,0.8088450797618966,1.6445651501196628,-0.613809285254711,1.2332088294189667,-0.3695251711327288,1.2838985750362097,-1.3116133841257678,-0.24503774966773847,1.5206274845608097,2.087516346686594,2.432256446318069,0.19857493350037805,1.4526723602880829,-0.34158367124160455,0.8088450797618966,0.9613654253667215,0.09772985746096338,1.5206274845608097,1.765685690904278,-0.08385693476833972,2.8406681128013975,1.373923307859532,2.513161047727077,-0.5990899607250865,1.1510683617802193,1.7472293962722831,-0.49730329369665177,-0.2861796454358755,-0.13699538899316593,-0.24503774966773847,1.4035922338561988,1.5590710612555858,0.7083452377706503,-1.5757009117269876,2.4485323268593073,2.863344325148585,0.19857493350037805,0.2974158983461496,0.43020921375824495,0.9398515677513489,-0.09708761132484221,2.3418704683845455,-0.21780189519795196,0.358212818135691,-0.03128805197937675,3.0342313533271863,0.3943400351131716,-1.2605731068481651,2.350148936285125,0.09772985746096338,0.5246297166579437,-0.5406616335135016,2.18215929435381,1.3540507039260963,1.9021217402473265,0.40632489423308854,3.6708025762594803,2.2835694069887835,0.358212818135691,2.26679759515337,1.9021217402473265,0.22346954691003423,-0.005212952459059928,1.6727608132509426,-0.32767317867730517,0.21103780546535914,0.19857493350037805,0.09772985746096338,1.710124790825368,1.625684832355376,-0.688095106410563,-0.34158367124160455,-0.044377623849349325,1.9110956664873515,1.0465360280824727 | 3,053 |
Cargo receptor activity | 11 | 13 | 3.053048 | 0.002265 | Q08380,P98164,P02786,O15260,Q8WTV0,P98155,Q07954,Q14108,Q92673,Q5KU26,P01130 | Functions | GO Molecular function | msigdb_gomf | 163,196,36,227,359,40,110,213,54,122,188 | 227,188,36,40,196,110,163,213,972,122,359,54,468 | 1.6914754779087535,1.866075878935031,2.779747026833827,2.7181568448827473,1.8297870381814723,2.26679759515337,1.9646281792457017,1.7472293962722831,0.16099777070340407,2.2161719066574945,1.1510683617802193,2.616602358730607,0.8856706691345428 | 3,053 |
Amyloid precursor protein metabolic process | 12 | 22 | 3.041886 | 0.002351 | Q15392,P62942,O95197,Q92542,P35610,Q14254,Q9Y287,P15260,Q92673,Q9NQX7,Q9NQC3,Q96P70 | Processes and pathways | GO Biological process | msigdb_gobp | 515,521,42,206,553,432,20,22,54,59,60,159 | 1006,42,1374,22,1944,553,1849,603,1257,521,1576,1543,432,515,206,54,159,2465,60,59,1619,20 | 0.13578741527968066,2.702652806647846,-0.1103540999259057,3.004880449945332,-0.3695251711327288,0.674400725375824,-0.32767317867730517,0.5943047502828036,-0.044377623849349325,0.7420652759647238,-0.20424086935988572,-0.19071746259586272,0.9613654253667215,0.7644222293835908,1.774890052445681,2.616602358730607,1.991196931629869,-0.6433848115667744,2.577044818596751,2.584978865712065,-0.21780189519795196,3.026907865726523 | 3,053 |
Clathrin coated endocytic vesicle membrane | 9 | 18 | 3.03576 | 0.002399 | O43493,P98164,P02786,P00533,P11717,P04114,Q14108,P20645,P01130 | Localization | GO Cellular component | msigdb_gocc | 3,196,36,335,109,144,213,312,188 | 3,2369,1451,335,188,36,144,109,514,312,353,946,1761,196,2213,213,776,636 | 3.585003342735257,-0.5990899607250865,-0.15037063254699395,1.2230116728735583,1.866075878935031,2.779747026833827,2.0788303063459717,2.26679759515337,0.7644222293835908,1.3040379142045533,1.1717250589049941,0.17355509404966507,-0.2861796454358755,1.8297870381814723,-0.511712584314456,1.7472293962722831,0.34611234668124813,0.5479614575971996 | 3,053 |
Intrinsic component of mitochondrial membrane | 22 | 41 | 3.028341 | 0.002459 | O96008,O60830,Q9BUR5,Q15070,Q9Y512,Q6UXV4,Q13505,Q99595,Q16891,Q9UG56,Q9HC21,O14925,Q9NVH1,Q9BPX6,Q6P4A7,Q8IWA4,Q9Y2R0,Q9H3K2,P12235,Q9BWH2,P57105,Q5XKP0 | Localization | GO Cellular component | msigdb_gocc | 519,10,268,16,531,534,23,30,416,300,299,173,448,447,317,467,90,226,100,498,503,250 | 173,745,10,780,705,1423,519,100,2969,1455,503,1637,23,16,690,1704,416,571,250,317,534,467,799,1469,1340,832,1674,30,447,268,498,226,652,299,448,1025,300,1080,90,1278,531 | 1.9289988637379116,0.3702841521879034,3.2637394965616733,0.33398257941175047,0.43020921375824495,-0.13699538899316593,0.7420652759647238,2.308631386581677,-1.363225981446116,-0.15037063254699395,0.7866818484921456,-0.2314007759263953,3.004880449945332,3.070707640988607,0.4539806748878796,-0.2587130568814146,1.01476116822825,0.6516446748258692,1.625684832355376,1.2838985750362097,0.7083452377706503,0.8856706691345428,0.3218233565713564,-0.15037063254699395,-0.08385693476833972,0.28516733659390786,-0.24503774966773847,2.863344325148585,0.9398515677513489,1.5206274845608097,0.7977754540117483,1.7008082712982846,0.5246297166579437,1.3540507039260963,0.9398515677513489,0.1231340177911712,1.3540507039260963,0.0849787193065716,2.3666686044852,-0.044377623849349325,0.7196100272359108 | 3,053 |
Golgi cisterna | 13 | 25 | 3.027566 | 0.002465 | O95249,Q8NBZ7,Q9H4A5,P04439,Q99523,Q10471,Q8NBN3,Q10472,Q9BXS4,Q92673,Q8WVQ1,Q9Y6B6,O00461 | Localization | GO Cellular component | msigdb_gocc | 224,258,167,105,77,331,47,178,50,54,247,313,120 | 120,224,105,1096,644,3022,331,178,951,1011,374,593,47,258,577,1493,247,54,870,77,50,579,167,981,313 | 2.2161719066574945,1.7008082712982846,2.2835694069887835,0.059377376010689153,0.5246297166579437,-2.196785358451848,1.2332088294189667,1.9110956664873515,0.17355509404966507,0.13578741527968066,1.1095074471795692,0.6173184799051494,2.663703430679951,1.5686385889352172,0.6402283550178628,-0.16378257437491706,1.635133356253012,2.616602358730607,0.2482403330382631,2.4485323268593073,2.6402026494641198,0.6402283550178628,1.9468428888650193,0.16099777070340407,1.3040379142045533 | 3,053 |
Peptide binding | 19 | 69 | 3.026879 | 0.002471 | O43731,Q9UIQ6,Q9Y287,P40855,P24390,P10321,Q9NZ08,Q92673,Q9NQX7,P01130,P01889,Q92973,O00264,P42892,P04439,Q03518,P55786,Q07954,O14773 | Functions | GO Molecular function | msigdb_gomf | 0,137,20,291,37,165,306,54,59,188,325,343,340,101,105,234,233,110,108 | 340,1031,1594,2895,108,2615,0,1370,941,1423,188,325,105,552,1627,1059,854,165,2210,2539,2476,37,1430,2106,1116,989,1188,2136,291,101,2686,2351,1976,783,818,1695,1792,233,2138,948,1886,1761,234,110,1514,2193,1576,1210,2960,690,515,572,359,54,343,636,1140,446,2851,977,1737,1050,59,306,1182,1319,137,20,1875 | 1.2127945785226133,0.11044822745697883,-0.21780189519795196,-1.1271584702084125,2.26679759515337,-0.7635596540122364,3.7488958239943146,-0.1103540999259057,0.17355509404966507,-0.13699538899316593,1.866075878935031,1.2535436771356345,2.2835694069887835,0.674400725375824,-0.2314007759263953,0.09772985746096338,0.26057972136771734,1.9557428487590485,-0.511712584314456,-0.7030923807336273,-0.6582416514877483,2.779747026833827,-0.13699538899316593,-0.45433286929698796,0.0465267852872829,0.14840860507849105,-0.005212952459059928,-0.4686137231142239,1.3838315350081463,2.300290100303094,-0.824808688320819,-0.5844158422252788,-0.38355670174670764,0.33398257941175047,0.2974158983461496,-0.2587130568814146,-0.299971419663726,1.6727608132509426,-0.4686137231142239,0.17355509404966507,-0.34158367124160455,-0.2861796454358755,1.6727608132509426,2.26679759515337,-0.17723144136555438,-0.49730329369665177,-0.20424086935988572,-0.018233230344920522,-1.328753282124742,0.4539806748878796,0.7644222293835908,0.6516446748258692,1.1510683617802193,2.616602358730607,1.2127945785226133,0.5479614575971996,0.03364265519892447,0.9398515677513489,-1.0456796307190568,0.16099777070340407,-0.27242694039497706,0.11044822745697883,2.584978865712065,1.334102702134965,0.007772986263866033,-0.07066185389454786,2.122122478433616,3.026907865726523,-0.32767317867730517 | 3,053 |
Inorganic anion transport | 15 | 27 | 3.024702 | 0.002489 | Q9H0H5,P54105,P55011,Q9Y277,P45880,Q9UHG3,P51798,Q9Y6M7,Q9UBX3,P51790,P04920,Q9C0H2,Q4KMQ2,P21796,Q9H813 | Processes and pathways | GO Biological process | msigdb_gobp | 324,354,390,251,135,235,269,403,113,239,275,19,244,151,89 | 2589,1595,275,1057,1096,151,135,239,269,354,390,1637,808,407,244,3005,2413,675,763,19,324,89,765,113,235,251,403 | -0.7483704240161151,-0.21780189519795196,1.4721773650526246,0.09772985746096338,0.059377376010689153,2.0439466216934568,2.1393434129981372,1.6633788128540579,1.5109728694831275,1.1717250589049941,1.0676115247162676,-0.2314007759263953,0.30963451704569495,1.0359660555856258,1.6445651501196628,-1.6857818609693211,-0.613809285254711,0.477640468160584,0.358212818135691,3.0342313533271863,1.2636815408562456,2.3749098883187894,0.358212818135691,2.26679759515337,1.6727608132509426,1.625684832355376,1.0465360280824727 | 3,053 |
Antiporter activity | 9 | 12 | 3.020844 | 0.002521 | P12235,P12236,P08195,P51798,P51790,Q9UBX3,P04920,Q92581,O95202 | Functions | GO Molecular function | msigdb_gomf | 100,103,328,269,239,113,275,214,249 | 249,275,395,328,100,103,1207,239,269,808,214,113 | 1.625684832355376,1.4721773650526246,1.0570844850930035,1.2433861353171847,2.308631386581677,2.291936121589696,-0.018233230344920522,1.6633788128540579,1.5109728694831275,0.30963451704569495,1.7472293962722831,2.26679759515337 | 3,053 |
Endoplasmic reticulum lumen | 25 | 62 | 3.010889 | 0.002605 | O14657,O43493,Q9Y680,P04114,Q08431,P07237,P05067,P19022,P13674,O00584,P27824,P53634,O95881,Q9NZ08,Q07065,Q14257,P07942,O43852,Q02818,Q06481,Q9BTY2,Q9NWM8,Q8NBJ4,Q9BV10,O76024 | Localization | GO Cellular component | msigdb_gocc | 379,3,132,144,278,405,29,418,422,39,425,170,431,306,309,57,314,62,322,74,84,474,96,231,372 | 39,379,3039,3,1595,62,2176,816,372,431,144,29,405,314,2845,1082,1924,422,684,1234,418,1756,2476,2105,1430,425,1507,1813,1972,989,2453,170,322,74,309,278,1043,57,1464,1794,489,628,972,1314,2081,923,96,1830,1860,658,1833,1046,1439,812,84,231,474,1586,306,768,1474,132 | 2.72589277449197,1.088601740735695,-3.502005126410417,3.585003342735257,-0.21780189519795196,2.5690994296216365,-0.49730329369665177,0.2974158983461496,1.1095074471795692,0.9613654253667215,2.0788303063459717,2.8859295440854202,1.0359660555856258,1.2939779145798287,-1.0456796307190568,0.0721946227962857,-0.35553424861853866,0.9934690240985936,0.4658244563610143,-0.03128805197937675,1.0041260536406191,-0.2861796454358755,-0.6582416514877483,-0.45433286929698796,-0.13699538899316593,0.9827899779325561,-0.17723144136555438,-0.31380251320317754,-0.38355670174670764,0.14840860507849105,-0.6433848115667744,1.937928245362595,1.2636815408562456,2.4566523252294235,1.31407865704397,1.4526723602880829,0.11044822745697883,2.584978865712065,-0.15037063254699395,-0.299971419663726,0.8198908418301337,0.5595870981994009,0.16099777070340407,-0.07066185389454786,-0.4400942588347924,0.19857493350037805,2.3335795218946296,-0.31380251320317754,-0.32767317867730517,0.512923337475363,-0.31380251320317754,0.11044822745697883,-0.13699538899316593,0.30963451704569495,2.4077523196496067,1.6821263466818883,0.8638375447218682,-0.20424086935988572,1.334102702134965,0.358212818135691,-0.15037063254699395,2.1650732388019702 | 3,053 |
Presynapse | 34 | 89 | 3.004555 | 0.00266 | P20339,O60499,Q5SQN1,Q9BTU6,Q13277,P05067,P19022,P61020,P27824,O15400,Q07021,P14672,P50897,P0DP25,Q13641,P20020,Q9UQB8,O15126,Q96A57,Q92542,Q7L0J3,Q9BT78,P61421,O43760,O75955,O00429,P51790,O76024,P11166,Q96A49,Q86Y82,P07196,P11279,P51149 | Localization | GO Cellular component | msigdb_gocc | 514,8,528,276,154,29,418,166,425,169,428,301,53,311,190,440,580,582,204,206,80,218,604,358,363,622,239,372,243,629,246,500,121,502 | 1325,680,1938,622,1476,582,169,358,1094,8,771,827,1126,363,372,29,500,1059,854,311,1922,243,121,301,418,440,514,3046,1944,1630,425,1882,890,990,1207,1409,966,53,1694,2187,502,1149,239,663,2651,166,795,604,2109,2701,1662,2524,918,2191,2435,428,154,1763,1576,2497,190,1358,1264,776,1011,528,80,741,246,1707,206,1181,629,204,636,2122,2487,1299,2994,926,713,2088,218,276,1065,2229,1714,580,2145 | -0.08385693476833972,0.4658244563610143,-0.3695251711327288,0.5595870981994009,-0.16378257437491706,0.6287863334786191,1.937928245362595,1.1510683617802193,0.059377376010689153,3.3336104827050863,0.34611234668124813,0.28516733659390786,0.03364265519892447,1.1303294043028353,1.1095074471795692,2.8859295440854202,0.7866818484921456,0.09772985746096338,0.26057972136771734,1.3040379142045533,-0.35553424861853866,1.6445651501196628,2.2161719066574945,1.3440861679024063,1.0041260536406191,0.9398515677513489,0.7644222293835908,-4.3164090138017865,-0.3695251711327288,-0.2314007759263953,0.9827899779325561,-0.34158367124160455,0.22346954691003423,0.14840860507849105,-0.018233230344920522,-0.12365661898489545,0.16099777070340407,2.616602358730607,-0.2587130568814146,-0.49730329369665177,0.7866818484921456,0.020724788531935035,1.6633788128540579,0.501189764703237,-0.7940850336780507,1.9557428487590485,0.3218233565713564,0.5943047502828036,-0.45433286929698796,-0.8402457773111607,-0.24503774966773847,-0.688095106410563,0.19857493350037805,-0.49730329369665177,-0.6285741297543339,0.9720888127376814,2.0351905672615014,-0.2861796454358755,-0.20424086935988572,-0.6731449738170256,1.857026591470633,-0.09708761132484221,-0.044377623849349325,0.34611234668124813,0.13578741527968066,0.7196100272359108,2.432256446318069,0.3823265059229414,1.635133356253012,-0.2587130568814146,1.774890052445681,0.007772986263866033,0.5595870981994009,1.7840786381977862,0.5479614575971996,-0.45433286929698796,-0.6582416514877483,-0.05750215436707501,-1.5757009117269876,0.19857493350037805,0.43020921375824495,-0.4400942588347924,1.737977340170717,1.4721773650526246,0.09772985746096338,-0.511712584314456,-0.2587130568814146,0.6402283550178628,-0.4686137231142239 | 3,053 |
Ion transmembrane transport | 59 | 151 | 3.001993 | 0.002682 | Q9HC07,O75844,P55011,O75964,P45880,P62942,Q70HW3,P05556,Q8N4V1,P51798,O75915,Q7KZN9,P05141,P05023,Q9Y6M7,Q9C0H2,P04920,P21796,Q8IUH4,Q15526,Q15043,P05067,O60831,Q96PU5,Q8NEW0,O43808,Q9HC21,Q8IYU8,Q9Y619,Q9UDW1,Q9HD20,P0DP25,Q9BPX6,Q6P4A7,P20020,P03915,P06756,Q8TB61,P98164,Q13423,P08195,P16615,Q04656,P30825,P00403,Q92581,Q9H2D1,P54709,P12235,P12236,Q9UHG3,Q9UBX3,P51790,Q4KMQ2,Q9Y277,O95202,O00400,P13073,P36543 | Processes and pathways | GO Biological process | msigdb_gobp | 128,130,390,260,135,521,266,524,267,269,523,143,395,394,403,19,275,151,279,408,407,29,540,287,32,538,299,435,180,183,182,311,447,317,440,439,195,68,196,197,328,202,203,79,463,214,92,480,100,103,235,113,239,244,251,249,508,380,381 | 2589,508,1252,964,3007,538,2279,2617,540,2177,2399,2178,1502,2753,2401,130,523,1095,260,249,463,439,275,394,29,395,524,1687,195,2707,2235,1374,1752,1057,328,755,1096,311,1628,1350,100,103,380,202,548,440,1097,1428,2735,2818,151,1148,2946,1944,2106,2649,79,2045,3034,1510,381,2107,1207,1409,135,1256,2954,966,239,269,720,819,1086,480,390,598,1009,604,948,1151,521,1119,196,1637,918,808,203,1288,2435,1979,2621,1488,197,1101,1462,1338,407,1011,408,613,244,2413,317,2956,266,143,279,1901,435,1064,267,1340,32,68,214,2201,1772,1439,1674,287,2994,926,447,1366,1613,763,19,731,2944,92,1067,652,128,299,182,726,765,113,183,1200,235,1873,913,927,1069,251,2533,1915,1278,180,403 | -0.7483704240161151,0.7755641462351951,-0.044377623849349325,0.16099777070340407,-1.7418453203119433,0.6970555073651654,-0.5552019842727006,-0.7635596540122364,0.6970555073651654,-0.49730329369665177,-0.613809285254711,-0.49730329369665177,-0.17723144136555438,-0.9181987971791161,-0.613809285254711,2.173622951248582,0.7308499991523034,0.059377376010689153,1.5494862574126163,1.625684832355376,0.8965525637862654,0.9398515677513489,1.4721773650526246,1.0570844850930035,2.8859295440854202,1.0570844850930035,0.7308499991523034,-0.2587130568814146,1.8297870381814723,-0.8557335336316402,-0.5261652660770593,-0.1103540999259057,-0.2861796454358755,0.09772985746096338,1.2433861353171847,0.358212818135691,0.059377376010689153,1.3040379142045533,-0.2314007759263953,-0.09708761132484221,2.308631386581677,2.291936121589696,1.088601740735695,1.7932515087502272,0.685740711671661,0.9398515677513489,0.059377376010689153,-0.13699538899316593,-0.8868625525092045,-0.9974667036146205,2.0439466216934568,0.020724788531935035,-1.277523820402273,-0.3695251711327288,-0.45433286929698796,-0.7940850336780507,2.432256446318069,-0.42589761215042704,-3.148782533062238,-0.17723144136555438,1.088601740735695,-0.45433286929698796,-0.018233230344920522,-0.12365661898489545,2.1393434129981372,-0.044377623849349325,-1.3116133841257678,0.16099777070340407,1.6633788128540579,1.5109728694831275,0.40632489423308854,0.2974158983461496,0.0721946227962857,0.8419112349230434,1.0676115247162676,0.6058246629645279,0.13578741527968066,0.5943047502828036,0.17355509404966507,0.020724788531935035,0.7420652759647238,0.0465267852872829,1.8297870381814723,-0.2314007759263953,0.19857493350037805,0.30963451704569495,1.7840786381977862,-0.05750215436707501,-0.6285741297543339,-0.38355670174670764,-0.7635596540122364,-0.16378257437491706,1.8206764297081328,0.059377376010689153,-0.15037063254699395,-0.08385693476833972,1.0359660555856258,0.13578741527968066,1.0359660555856258,0.5827586084337831,1.6445651501196628,-0.613809285254711,1.2838985750362097,-1.3116133841257678,1.5206274845608097,2.087516346686594,1.4526723602880829,-0.34158367124160455,0.9613654253667215,0.09772985746096338,1.5206274845608097,-0.08385693476833972,2.8406681128013975,2.513161047727077,1.7472293962722831,-0.49730329369665177,-0.2861796454358755,-0.13699538899316593,-0.24503774966773847,1.4035922338561988,-1.5757009117269876,0.19857493350037805,0.9398515677513489,-0.09708761132484221,-0.21780189519795196,0.358212818135691,3.0342313533271863,0.3943400351131716,-1.2605731068481651,2.350148936285125,0.09772985746096338,0.5246297166579437,2.18215929435381,1.3540507039260963,1.9021217402473265,0.40632489423308854,0.358212818135691,2.26679759515337,1.9021217402473265,-0.005212952459059928,1.6727608132509426,-0.32767317867730517,0.21103780546535914,0.19857493350037805,0.09772985746096338,1.625684832355376,-0.688095106410563,-0.34158367124160455,-0.044377623849349325,1.9110956664873515,1.0465360280824727 | 3,053 |
Calcium signaling pathway | 11 | 16 | 3.001958 | 0.002682 | P12235,P20020,P45880,P12236,P16615,P05141,P00533,P21796,Q9Y277,P0DP25,P46020 | Processes and pathways | KEGG Pathways | msigdb_kegg | 100,440,135,103,202,395,335,151,251,311,350 | 335,395,311,100,103,202,548,440,151,135,350,1514,2193,909,1200,251 | 1.2230116728735583,1.0570844850930035,1.3040379142045533,2.308631386581677,2.291936121589696,1.7932515087502272,0.685740711671661,0.9398515677513489,2.0439466216934568,2.1393434129981372,1.192300224783089,-0.17723144136555438,-0.49730329369665177,0.21103780546535914,-0.005212952459059928,1.625684832355376 | 3,053 |
Cell adhesion molecules cams | 11 | 13 | 2.991328 | 0.002778 | Q9Y624,P06756,P19022,P10321,P10586,P01889,Q16625,P04439,Q92896,Q92692,Q5ZPR3 | Processes and pathways | KEGG Pathways | msigdb_kegg | 352,195,418,165,230,325,134,105,111,473,157 | 325,105,524,195,165,230,418,1190,134,157,473,111,352 | 1.2535436771356345,2.2835694069887835,0.7308499991523034,1.8297870381814723,1.9557428487590485,1.6821263466818883,1.0041260536406191,-0.005212952459059928,2.1479335171777034,2.0088372660094183,0.8638375447218682,2.26679759515337,1.192300224783089 | 3,053 |
Inner mitochondrial membrane protein complex | 30 | 73 | 2.989915 | 0.002791 | O75964,P14406,O60830,Q9BUR5,Q9Y6M9,Q96CU9,Q9P0J0,Q9Y512,Q13505,Q99595,Q16891,O14925,Q8IYU8,Q9UDW1,Q9NVH1,Q9BPX6,P03886,O75438,P03915,O14949,O96000,P00403,Q86Y39,O43676,O95169,P12236,Q3ZCQ8,P22695,Q5XKP0,P13073 | Localization | GO Cellular component | msigdb_gocc | 260,9,10,268,271,530,400,531,23,30,416,173,435,183,448,447,316,189,439,65,462,463,82,85,475,103,491,490,250,380 | 1252,173,65,85,10,2178,815,780,189,1751,1095,260,1282,475,2732,1167,462,463,316,439,1687,755,2708,1628,103,380,9,2817,2151,2870,1097,944,490,1148,2946,3023,2263,2045,2518,1510,2969,2954,2873,1037,598,1259,1009,23,2161,1383,416,491,571,250,534,82,435,1340,530,1245,30,926,447,268,2276,448,1025,400,183,2038,1278,531,271 | -0.044377623849349325,1.9289988637379116,2.537203722894823,2.3913555626564813,3.2637394965616733,-0.49730329369665177,0.2974158983461496,0.33398257941175047,1.857026591470633,-0.2861796454358755,0.059377376010689153,1.5494862574126163,-0.05750215436707501,0.8528860938012238,-0.8868625525092045,0.007772986263866033,0.8965525637862654,0.8965525637862654,1.2838985750362097,0.9398515677513489,-0.2587130568814146,0.358212818135691,-0.8557335336316402,-0.2314007759263953,2.291936121589696,1.088601740735695,3.326661548929698,-0.9974667036146205,-0.4829371027702765,-1.0781003736110784,0.059377376010689153,0.17355509404966507,0.8088450797618966,0.020724788531935035,-1.277523820402273,-2.2176680858752387,-0.5406616335135016,-0.42589761215042704,-0.688095106410563,-0.17723144136555438,-1.363225981446116,-1.3116133841257678,-1.0781003736110784,0.11044822745697883,0.6058246629645279,-0.044377623849349325,0.13578741527968066,3.004880449945332,-0.4829371027702765,-0.1103540999259057,1.01476116822825,0.8088450797618966,0.6516446748258692,1.625684832355376,0.7083452377706503,2.4159324560048354,0.9613654253667215,-0.08385693476833972,0.7196100272359108,-0.03128805197937675,2.863344325148585,0.19857493350037805,0.9398515677513489,1.5206274845608097,-0.5406616335135016,0.9398515677513489,0.1231340177911712,1.0465360280824727,1.9021217402473265,-0.41174265253282316,-0.044377623849349325,0.7196100272359108,1.5109728694831275 | 3,053 |
Lipid transport | 11 | 24 | 2.986314 | 0.002824 | O15118,P61916,P98155,Q9NV96,Q9BUR5,P04114,Q14849,Q4KMQ2,Q9H2C2,P01130,Q9BQE5 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 164,261,40,106,268,144,49,244,87,188,127 | 886,164,2827,188,144,1352,2429,261,40,2380,49,244,1953,2999,871,298,127,1869,268,1472,1247,87,106,573 | 0.22346954691003423,1.9557428487590485,-1.0134824950248342,1.866075878935031,2.0788303063459717,-0.09708761132484221,-0.6285741297543339,1.5494862574126163,2.7181568448827473,-0.5990899607250865,2.6480472532459483,1.6445651501196628,-0.3695251711327288,-1.6304066202769507,0.2482403330382631,1.363996390617815,2.18215929435381,-0.32767317867730517,1.5206274845608097,-0.15037063254699395,-0.03128805197937675,2.3831388606343356,2.2835694069887835,0.6516446748258692 | 3,053 |
Other glycan degradation | 8 | 9 | 2.963568 | 0.003041 | O00462,P16278,P06865,P04066,P07686,Q99519,Q9BTY2,O00754 | Processes and pathways | KEGG Pathways | msigdb_kegg | 97,73,72,43,208,148,84,181 | 97,181,288,43,72,208,73,148,84 | 2.316960023648094,1.9021217402473265,1.3937211509001355,2.702652806647846,2.4728566349196144,1.765685690904278,2.4728566349196144,2.070130363883016,2.4077523196496067 | 3,053 |
EGF-like domain [IPR000742] | 8 | 11 | 2.961946 | 0.003057 | P98164,P48960,P98155,Q07954,O94813,Q08431,P14543,P01130 | Sequence | InterPro Domain | interpro_domain | 196,102,40,110,207,278,123,188 | 207,188,314,1082,123,102,40,196,110,278,551 | 1.765685690904278,1.866075878935031,1.2939779145798287,0.0721946227962857,2.199192059706801,2.300290100303094,2.7181568448827473,1.8297870381814723,2.26679759515337,1.4526723602880829,0.685740711671661 | 3,053 |
Organic anion transmembrane transporter activity | 19 | 28 | 2.956289 | 0.003114 | Q96QD8,Q9H9B4,P05141,Q9Y6M7,O43808,Q9HC21,Q9Y619,Q99808,Q8TB61,P08195,Q6NUK1,P30825,Q9H2D1,P12235,Q15758,P12236,Q9UBX3,P11166,O00400 | Functions | GO Molecular function | msigdb_gomf | 259,652,395,403,538,299,180,713,68,328,332,79,92,100,613,103,113,243,508 | 508,538,2401,395,328,243,100,103,79,1207,720,819,808,613,332,1953,68,1674,259,713,92,1067,652,299,113,913,180,403 | 0.7755641462351951,0.6970555073651654,-0.613809285254711,1.0570844850930035,1.2433861353171847,1.6445651501196628,2.308631386581677,2.291936121589696,2.432256446318069,-0.018233230344920522,0.40632489423308854,0.2974158983461496,0.30963451704569495,0.5827586084337831,1.2332088294189667,-0.3695251711327288,2.513161047727077,-0.24503774966773847,1.5590710612555858,0.43020921375824495,2.350148936285125,0.09772985746096338,0.5246297166579437,1.3540507039260963,2.26679759515337,0.21103780546535914,1.9110956664873515,1.0465360280824727 | 3,053 |
Abnormal retinal artery morphology | 12 | 23 | 2.952298 | 0.003154 | P21964,P16278,P06865,P10619,P07686,Q99519,P07602,P17900,Q9Y4P3,P03886,Q13510,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 228,73,72,141,208,148,21,88,384,316,318,351 | 1718,316,439,72,21,208,141,2558,73,88,228,1925,2455,708,2458,318,1010,2486,1863,148,351,1028,384 | -0.27242694039497706,1.2838985750362097,0.9398515677513489,2.4728566349196144,3.0195749043603826,1.765685690904278,2.096188534692145,-0.7181371319149215,2.4728566349196144,2.3749098883187894,1.6914754779087535,-0.35553424861853866,-0.6433848115667744,0.43020921375824495,-0.6433848115667744,1.273799811880788,0.13578741527968066,-0.6582416514877483,-0.32767317867730517,2.070130363883016,1.192300224783089,0.1231340177911712,1.088601740735695 | 3,053 |
Sterol binding | 6 | 15 | 2.94962 | 0.003182 | O15118,P45880,Q14849,Q14108,P21796,O95772 | Functions | GO Molecular function | msigdb_gomf | 164,135,49,213,151,124 | 164,1185,124,1752,151,1352,2429,553,135,261,213,49,871,1472,1247 | 1.9557428487590485,-0.005212952459059928,2.1906823149730266,-0.2861796454358755,2.0439466216934568,-0.09708761132484221,-0.6285741297543339,0.674400725375824,2.1393434129981372,1.5494862574126163,1.7472293962722831,2.6480472532459483,0.2482403330382631,-0.15037063254699395,-0.03128805197937675 | 3,053 |
Cellular homeostasis | 49 | 135 | 2.947861 | 0.0032 | Q9HC07,P52789,P55011,P09601,P62942,P05023,Q8N511,Q9Y6M7,P04920,Q15043,Q96TC7,P05067,Q96A33,Q8NEW0,Q96PU5,Q16891,P17612,P02786,Q93050,Q8IYU8,P50897,Q9HD20,P0DP25,Q9BPX6,Q9NQC3,P20020,Q9P0T7,Q92544,P06756,O75787,P16615,Q04656,P07686,Q7L0J3,Q15904,Q14964,Q92581,P10253,P54709,P54105,Q9Y487,O75503,P09622,P51790,O76024,Q9BWH2,P51149,Q4KMQ2,O95202 | Processes and pathways | GO Biological process | msigdb_gobp | 128,257,390,133,521,394,270,403,275,407,544,29,285,32,287,416,548,36,171,435,53,182,311,447,60,440,64,323,195,320,202,203,208,80,209,465,214,93,480,354,360,104,107,239,372,498,502,244,249 | 680,1229,1476,745,2617,617,2177,104,320,705,2643,372,249,1233,1811,1331,36,3006,275,394,29,1687,195,208,1374,552,1752,1349,1754,133,107,1096,311,93,1923,1283,1234,2210,202,748,548,2514,440,2237,1352,2105,1944,1430,1507,2774,2700,2901,2649,2963,2107,1409,53,502,1851,644,239,1309,257,354,480,390,2239,604,1151,521,709,1820,1119,918,203,1979,592,1514,1574,1261,1359,641,465,407,2195,1011,209,2271,2197,2746,416,244,2413,2956,1670,80,1901,799,1469,435,270,1340,32,323,214,171,285,760,2677,1439,287,1804,544,713,447,498,763,1219,2944,1738,128,182,60,686,64,1200,1873,927,1069,1003,885,2730,360,1278,403 | 0.4658244563610143,-0.03128805197937675,-0.16378257437491706,0.3702841521879034,-0.7635596540122364,0.571186102927646,-0.49730329369665177,2.2835694069887835,1.2636815408562456,0.43020921375824495,-0.7940850336780507,1.1095074471795692,1.625684832355376,-0.03128805197937675,-0.31380251320317754,-0.08385693476833972,2.779747026833827,-1.7043922659603603,1.4721773650526246,1.0570844850930035,2.8859295440854202,-0.2587130568814146,1.8297870381814723,1.765685690904278,-0.1103540999259057,0.674400725375824,-0.2861796454358755,-0.09708761132484221,-0.2861796454358755,2.1479335171777034,2.2751899128159465,0.059377376010689153,1.3040379142045533,2.3418704683845455,-0.35553424861853866,-0.05750215436707501,-0.03128805197937675,-0.511712584314456,1.7932515087502272,0.3702841521879034,0.685740711671661,-0.688095106410563,0.9398515677513489,-0.5261652660770593,-0.09708761132484221,-0.45433286929698796,-0.3695251711327288,-0.13699538899316593,-0.17723144136555438,-0.9339456025039627,-0.8402457773111607,-1.1436268388419184,-0.7940850336780507,-1.3459573008332442,-0.45433286929698796,-0.12365661898489545,2.616602358730607,0.7866818484921456,-0.32767317867730517,0.5246297166579437,1.6633788128540579,-0.07066185389454786,1.5686385889352172,1.1717250589049941,0.8419112349230434,1.0676115247162676,-0.5261652660770593,0.5943047502828036,0.020724788531935035,0.7420652759647238,0.43020921375824495,-0.31380251320317754,0.0465267852872829,0.19857493350037805,1.7840786381977862,-0.38355670174670764,0.6173184799051494,-0.17723144136555438,-0.20424086935988572,-0.044377623849349325,-0.09708761132484221,0.5363090433704797,0.8965525637862654,1.0359660555856258,-0.49730329369665177,0.13578741527968066,1.765685690904278,-0.5406616335135016,-0.49730329369665177,-0.9025045780882558,1.01476116822825,1.6445651501196628,-0.613809285254711,-1.3116133841257678,-0.24503774966773847,2.432256446318069,-0.34158367124160455,0.3218233565713564,-0.15037063254699395,0.9613654253667215,1.5109728694831275,-0.08385693476833972,2.8406681128013975,1.2636815408562456,1.7472293962722831,1.937928245362595,1.4134448616858115,0.358212818135691,-0.8094218959475288,-0.13699538899316593,1.4035922338561988,-0.299971419663726,0.6970555073651654,0.43020921375824495,0.9398515677513489,0.7977754540117483,0.358212818135691,-0.018233230344920522,-1.2605731068481651,-0.27242694039497706,2.18215929435381,1.9021217402473265,2.577044818596751,0.4658244563610143,2.553174480013193,-0.005212952459059928,-0.32767317867730517,0.19857493350037805,0.09772985746096338,0.14840860507849105,0.23587033191152165,-0.8712723322607361,1.1510683617802193,-0.044377623849349325,1.0465360280824727 | 3,053 |
Snare complex | 8 | 15 | 2.942337 | 0.003257 | O95249,Q13190,Q9P2W9,O60499,O15400,Q86Y82,Q13277,Q9UNK0 | Localization | GO Cellular component | msigdb_gocc | 224,225,136,8,169,246,154,319 | 1325,169,916,8,790,224,353,663,225,154,528,246,1090,136,319 | -0.08385693476833972,1.937928245362595,0.19857493350037805,3.3336104827050863,0.3218233565713564,1.7008082712982846,1.1717250589049941,0.501189764703237,1.7008082712982846,2.0351905672615014,0.7196100272359108,1.635133356253012,0.0721946227962857,2.1393434129981372,1.273799811880788 | 3,053 |
Clathrin coated endocytic vesicle | 9 | 23 | 2.941714 | 0.003264 | O43493,P98164,P02786,P00533,P11717,P04114,Q14108,P20645,P01130 | Localization | GO Cellular component | msigdb_gocc | 3,196,36,335,109,144,213,312,188 | 3,2369,1451,335,188,36,144,1059,854,109,514,312,966,353,946,1761,196,2213,1576,213,776,636,2036 | 3.585003342735257,-0.5990899607250865,-0.15037063254699395,1.2230116728735583,1.866075878935031,2.779747026833827,2.0788303063459717,0.09772985746096338,0.26057972136771734,2.26679759515337,0.7644222293835908,1.3040379142045533,0.16099777070340407,1.1717250589049941,0.17355509404966507,-0.2861796454358755,1.8297870381814723,-0.511712584314456,-0.20424086935988572,1.7472293962722831,0.34611234668124813,0.5479614575971996,-0.41174265253282316 | 3,053 |
Dysostosis multiplex | 7 | 9 | 2.938906 | 0.003294 | P54802,P16278,P04066,P10619,Q99519,O00754,P15586 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 160,73,43,141,148,181,184 | 181,43,241,141,184,73,160,760,148 | 1.9021217402473265,2.702652806647846,1.6539802803309698,2.096188534692145,1.8841289535850934,2.4728566349196144,1.9823551672513169,0.358212818135691,2.070130363883016 | 3,053 |
Glycoprotein metabolic process | 29 | 59 | 2.934878 | 0.003337 | Q9HC07,P04843,Q9BT22,P62820,Q9Y287,Q2TAA5,Q7LGA3,Q99805,Q9H9S5,O15118,Q9H0U4,P35610,Q10472,Q9BXS4,O00754,Q9NQX7,P33908,P46977,Q04656,Q86SF2,Q92542,Q10471,P26572,O43505,Q9Y251,O00462,Q9BV10,Q9NX62,Q8WVQ1 | Processes and pathways | GO Biological process | msigdb_gobp | 128,520,396,398,20,409,24,26,158,164,560,553,178,50,181,59,315,441,203,595,206,331,464,220,223,97,231,112,247 | 97,1623,181,164,1968,220,1329,2176,887,943,1719,520,1426,684,464,315,890,553,1693,441,3037,398,2434,969,203,2791,331,178,1640,1464,593,409,1022,24,1314,595,649,247,206,870,2994,26,396,231,50,731,560,1648,787,158,128,59,112,1619,1586,1200,223,20,688 | 2.316960023648094,-0.2314007759263953,1.9021217402473265,1.9557428487590485,-0.38355670174670764,1.7194251000762824,-0.08385693476833972,-0.49730329369665177,0.22346954691003423,0.17355509404966507,-0.27242694039497706,0.7420652759647238,-0.13699538899316593,0.4658244563610143,0.8965525637862654,1.2939779145798287,0.22346954691003423,0.674400725375824,-0.2587130568814146,0.9398515677513489,-3.417750217818519,1.0465360280824727,-0.6285741297543339,0.16099777070340407,1.7840786381977862,-0.9497453913983102,1.2332088294189667,1.9110956664873515,-0.2314007759263953,-0.15037063254699395,0.6173184799051494,1.0359660555856258,0.1231340177911712,2.9679765780397287,-0.07066185389454786,0.6173184799051494,0.5246297166579437,1.635133356253012,1.774890052445681,0.2482403330382631,-1.5757009117269876,2.9382790868184965,1.0570844850930035,1.6821263466818883,2.6402026494641198,0.3943400351131716,0.674400725375824,-0.2314007759263953,0.33398257941175047,2.0088372660094183,2.18215929435381,2.584978865712065,2.26679759515337,-0.21780189519795196,-0.20424086935988572,-0.005212952459059928,1.710124790825368,3.026907865726523,0.4658244563610143 | 3,053 |
Apical plasma membrane | 23 | 47 | 2.932099 | 0.003367 | Q16625,P55011,P05023,Q9Y6M7,O00592,P04920,Q15043,Q13277,P07858,Q86UE4,P19022,Q14254,P20020,O75787,P98164,P08195,Q04656,P30825,Q9NV96,O75955,P51790,P11166,P36543 | Localization | GO Cellular component | msigdb_gocc | 134,390,394,403,146,275,407,154,27,33,418,432,440,320,196,328,203,79,106,363,239,243,381 | 680,146,2279,320,363,2985,275,394,27,1057,328,1349,1627,243,2018,2182,418,440,1428,2104,79,1883,381,1483,2107,1207,239,819,480,390,604,196,203,154,2761,432,407,1930,134,33,823,713,671,106,814,1397,403 | 0.4658244563610143,2.070130363883016,-0.5552019842727006,1.2636815408562456,1.1303294043028353,-1.5037706134431923,1.4721773650526246,1.0570844850930035,2.9233715788819468,0.09772985746096338,1.2433861353171847,-0.09708761132484221,-0.2314007759263953,1.6445651501196628,-0.41174265253282316,-0.49730329369665177,1.0041260536406191,0.9398515677513489,-0.13699538899316593,-0.45433286929698796,2.432256446318069,-0.34158367124160455,1.088601740735695,-0.16378257437491706,-0.45433286929698796,-0.018233230344920522,1.6633788128540579,0.2974158983461496,0.8419112349230434,1.0676115247162676,0.5943047502828036,1.8297870381814723,1.7840786381977862,2.0351905672615014,-0.9181987971791161,0.9613654253667215,1.0359660555856258,-0.35553424861853866,2.1479335171777034,2.8254996778955275,0.2974158983461496,0.43020921375824495,0.4894288560742516,2.2835694069887835,0.30963451704569495,-0.1103540999259057,1.0465360280824727 | 3,053 |
SLC25 family of mitochondrial transporters | 11 | 20 | 2.927721 | 0.003415 | P12235,P12236,Q70HW3,P05141,Q9HC21,Q6NUK1,Q9UBX3,Q9Y619,Q9H2D1,Q9BSK2,Q9NZJ7 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 100,103,266,395,299,332,113,180,92,95,351 | 3007,538,2401,395,100,103,720,1637,808,332,266,95,92,1067,299,351,113,913,180,402 | -1.7418453203119433,0.6970555073651654,-0.613809285254711,1.0570844850930035,2.308631386581677,2.291936121589696,0.40632489423308854,-0.2314007759263953,0.30963451704569495,1.2332088294189667,1.5206274845608097,2.3418704683845455,2.350148936285125,0.09772985746096338,1.3540507039260963,1.192300224783089,2.26679759515337,0.21103780546535914,1.9110956664873515,1.0465360280824727 | 3,053 |
Mitochondrial carrier domain superfamily [IPR023395] | 11 | 20 | 2.927721 | 0.003415 | P12235,P12236,Q70HW3,P05141,Q9HC21,Q6NUK1,Q9UBX3,Q9Y619,Q9H2D1,Q9BSK2,Q9NZJ7 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 100,103,266,395,299,332,113,180,92,95,351 | 3007,538,2401,395,100,103,720,1637,808,332,266,95,92,1067,299,351,113,913,180,402 | -1.7418453203119433,0.6970555073651654,-0.613809285254711,1.0570844850930035,2.308631386581677,2.291936121589696,0.40632489423308854,-0.2314007759263953,0.30963451704569495,1.2332088294189667,1.5206274845608097,2.3418704683845455,2.350148936285125,0.09772985746096338,1.3540507039260963,1.192300224783089,2.26679759515337,0.21103780546535914,1.9110956664873515,1.0465360280824727 | 3,053 |
Mitochondrial substrate/solute carrier [IPR018108] | 11 | 20 | 2.927721 | 0.003415 | P12235,P12236,Q70HW3,P05141,Q9HC21,Q6NUK1,Q9UBX3,Q9Y619,Q9H2D1,Q9BSK2,Q9NZJ7 | Sequence | InterPro Repeat | interpro_repeat | 100,103,266,395,299,332,113,180,92,95,351 | 3007,538,2401,395,100,103,720,1637,808,332,266,95,92,1067,299,351,113,913,180,402 | -1.7418453203119433,0.6970555073651654,-0.613809285254711,1.0570844850930035,2.308631386581677,2.291936121589696,0.40632489423308854,-0.2314007759263953,0.30963451704569495,1.2332088294189667,1.5206274845608097,2.3418704683845455,2.350148936285125,0.09772985746096338,1.3540507039260963,1.192300224783089,2.26679759515337,0.21103780546535914,1.9110956664873515,1.0465360280824727 | 3,053 |
Intrinsic component of mitochondrial inner membrane | 16 | 29 | 2.926319 | 0.00343 | Q16891,Q9NVH1,Q9H3K2,O60830,Q9UG56,Q9BUR5,Q9HC21,O14925,Q15070,Q9Y512,Q6UXV4,Q13505,Q9Y2R0,Q5XKP0,Q6P4A7,Q99595 | Localization | GO Cellular component | msigdb_gocc | 416,448,226,10,300,268,299,173,16,531,534,23,90,250,317,30 | 173,745,10,780,705,2969,1455,1637,23,16,1704,416,571,250,317,534,1340,1674,30,268,226,652,299,448,1025,300,90,1278,531 | 1.9289988637379116,0.3702841521879034,3.2637394965616733,0.33398257941175047,0.43020921375824495,-1.363225981446116,-0.15037063254699395,-0.2314007759263953,3.004880449945332,3.070707640988607,-0.2587130568814146,1.01476116822825,0.6516446748258692,1.625684832355376,1.2838985750362097,0.7083452377706503,-0.08385693476833972,-0.24503774966773847,2.863344325148585,1.5206274845608097,1.7008082712982846,0.5246297166579437,1.3540507039260963,0.9398515677513489,0.1231340177911712,1.3540507039260963,2.3666686044852,-0.044377623849349325,0.7196100272359108 | 3,053 |
Amyloid beta binding | 6 | 12 | 2.914946 | 0.003558 | Q07954,Q9Y287,Q92673,O00264,Q9NQX7,P01130 | Functions | GO Molecular function | msigdb_gomf | 110,20,54,340,59,188 | 340,188,989,1886,110,1576,359,54,1140,59,1319,20 | 1.2127945785226133,1.866075878935031,0.14840860507849105,-0.34158367124160455,2.26679759515337,-0.20424086935988572,1.1510683617802193,2.616602358730607,0.03364265519892447,2.584978865712065,-0.07066185389454786,3.026907865726523 | 3,053 |
Lytic vacuole organization | 18 | 27 | 2.914836 | 0.003559 | Q9HC07,P04062,P54802,Q6IAA8,Q9P0T7,O75787,Q8NHS3,O75503,Q8N511,P42345,P07686,Q14964,O14773,P11117,P50897,Q14108,P51149,P10253 | Processes and pathways | GO Biological process | msigdb_gobp | 128,288,160,386,64,320,296,104,270,554,208,465,108,83,53,213,502,93 | 1229,108,104,320,288,208,93,83,554,53,502,160,1541,213,465,386,270,296,760,1299,579,128,3032,64,1714,1003,789 | -0.03128805197937675,2.26679759515337,2.2835694069887835,1.2636815408562456,1.3937211509001355,1.765685690904278,2.3418704683845455,2.4077523196496067,0.674400725375824,2.616602358730607,0.7866818484921456,1.9823551672513169,-0.19071746259586272,1.7472293962722831,0.8965525637862654,1.0781172443576843,1.5109728694831275,1.373923307859532,0.358212818135691,-0.05750215436707501,0.6402283550178628,2.18215929435381,-3.0205793937440046,2.553174480013193,-0.2587130568814146,0.14840860507849105,0.33398257941175047 | 3,053 |
Golgi apparatus | 75 | 177 | 2.913705 | 0.003572 | Q9HC07,O43493,Q6IAA8,P80303,P09601,O60499,A1L0T0,O60637,Q9BRK5,Q9HB40,Q8NC54,Q9Y287,O15127,Q8IUH4,Q15043,Q8IYS2,P05067,Q9H9S5,Q8NEW0,O95302,Q15012,P24390,O14681,O95067,Q9H4A5,Q6P4E1,Q93050,Q9HD45,Q9H0U4,Q9UG56,Q8NBN3,O95070,Q14789,P50897,Q969E2,Q8IZA0,Q9UID3,P33908,P19021,O15258,Q8TBA6,Q969S3,O75071,Q02818,Q92520,Q9GZM5,P16278,Q04656,Q86SF2,Q99523,Q16706,Q10471,Q7RTS9,Q6NUQ4,Q5VU43,P67812,Q9NWM8,Q6ZRP7,Q8NBJ4,Q13190,O15260,P10586,O43760,P04439,O75955,Q92896,Q8IXU6,Q9NX62,P11717,Q6NUQ1,Q86Y82,Q8WVQ1,Q5KU26,O00461,Q96GQ5 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 128,3,386,6,133,8,389,11,142,145,17,20,147,279,407,155,29,158,32,161,35,37,421,547,167,41,171,172,560,300,47,303,433,53,444,56,573,315,63,438,577,578,67,322,586,199,73,203,595,77,593,331,461,338,600,341,474,221,96,225,227,230,358,105,363,111,492,112,109,366,246,247,122,120,509 | 389,1280,1229,984,120,1716,421,1326,147,438,227,1994,1995,1747,2368,3,358,965,8,11,1879,2704,67,1843,2797,2681,363,547,303,161,1073,2017,105,29,2937,1374,133,230,2845,109,73,1235,63,1352,37,1084,2515,2594,2282,315,1925,793,714,667,2046,1036,2668,1600,603,783,966,1117,53,2902,2317,2760,2864,2266,1634,341,6,2434,1821,322,203,2190,3022,331,728,225,2111,2321,920,433,1176,35,407,593,1643,122,2986,600,730,724,2501,386,366,338,41,1363,1291,221,2980,461,1550,595,2763,1293,246,279,2297,2120,492,2029,155,56,1609,2674,1137,96,47,17,32,577,2300,2983,247,586,1297,111,2201,171,444,578,629,2387,509,2247,871,77,1015,2907,142,1556,1472,2553,199,560,1049,167,787,3024,2391,158,1051,1197,145,128,726,172,1616,2469,660,474,112,814,632,300,1080,573,1052,1809,2339,20,2662,2066,736 | 1.0676115247162676,-0.05750215436707501,-0.03128805197937675,0.14840860507849105,2.2161719066574945,-0.27242694039497706,0.9934690240985936,-0.08385693476833972,2.070130363883016,0.9398515677513489,1.6914754779087535,-0.3976291060973344,-0.3976291060973344,-0.2861796454358755,-0.5990899607250865,3.585003342735257,1.1510683617802193,0.16099777070340407,3.3336104827050863,3.256705324195762,-0.34158367124160455,-0.8557335336316402,2.513161047727077,-0.32767317867730517,-0.965598565884847,-0.824808688320819,1.1303294043028353,0.685740711671661,1.334102702134965,1.9734989342155895,0.0849787193065716,-0.41174265253282316,2.2835694069887835,2.8859295440854202,-1.2436844181072007,-0.1103540999259057,2.1479335171777034,1.6821263466818883,-1.0456796307190568,2.26679759515337,2.4728566349196144,-0.03128805197937675,2.5690994296216365,-0.09708761132484221,2.779747026833827,0.0721946227962857,-0.688095106410563,-0.7483704240161151,-0.5552019842727006,1.2939779145798287,-0.35553424861853866,0.3218233565713564,0.4182812364739646,0.4894288560742516,-0.42589761215042704,0.11044822745697883,-0.8094218959475288,-0.21780189519795196,0.5943047502828036,0.33398257941175047,0.16099777070340407,0.0465267852872829,2.616602358730607,-1.1436268388419184,-0.5697866191684537,-0.9181987971791161,-1.0618618334058418,-0.5406616335135016,-0.2314007759263953,1.2127945785226133,3.409499537081338,-0.6285741297543339,-0.31380251320317754,1.2636815408562456,1.7840786381977862,-0.49730329369665177,-2.196785358451848,1.2332088294189667,0.3943400351131716,1.7008082712982846,-0.45433286929698796,-0.5697866191684537,0.19857493350037805,0.9613654253667215,0.007772986263866033,2.8026699653933203,1.0359660555856258,0.6173184799051494,-0.2314007759263953,2.2161719066574945,-1.5037706134431923,0.6058246629645279,0.3943400351131716,0.40632489423308854,-0.6731449738170256,1.0781172443576843,1.1199288473059854,1.2230116728735583,2.7181568448827473,-0.09708761132484221,-0.05750215436707501,1.7194251000762824,-1.4329583992749886,0.9074114928163481,-0.19071746259586272,0.6173184799051494,-0.9181987971791161,-0.05750215436707501,1.635133356253012,1.4526723602880829,-0.5552019842727006,-0.45433286929698796,0.8088450797618966,-0.41174265253282316,2.0351905672615014,2.5929016072601465,-0.21780189519795196,-0.8094218959475288,0.03364265519892447,2.3335795218946296,2.663703430679951,3.0415453946035886,2.8406681128013975,0.6402283550178628,-0.5552019842727006,-1.4859642707038754,1.635133356253012,0.6287863334786191,-0.05750215436707501,2.26679759515337,-0.49730329369665177,1.937928245362595,0.9398515677513489,0.6402283550178628,0.5595870981994009,-0.5990899607250865,0.7755641462351951,-0.5261652660770593,0.2482403330382631,2.4485323268593073,0.13578741527968066,-1.1436268388419184,2.096188534692145,-0.19071746259586272,-0.15037063254699395,-0.7030923807336273,1.8115503448124948,0.674400725375824,0.11044822745697883,1.9468428888650193,0.33398257941175047,-2.238650844362879,-0.5990899607250865,2.0088372660094183,0.11044822745697883,-0.005212952459059928,2.0788303063459717,2.18215929435381,0.40632489423308854,1.937928245362595,-0.21780189519795196,-0.6433848115667744,0.512923337475363,0.8638375447218682,2.26679759515337,0.30963451704569495,0.5595870981994009,1.3540507039260963,0.0849787193065716,0.6516446748258692,0.11044822745697883,-0.299971419663726,-0.5697866191684537,3.026907865726523,-0.7940850336780507,-0.42589761215042704,0.3943400351131716 | 3,053 |
Snap receptor activity | 8 | 13 | 2.903449 | 0.003691 | O95249,Q13190,Q9P2W9,O60499,O15400,Q86Y82,Q13277,Q9UNK0 | Functions | GO Molecular function | msigdb_gomf | 224,225,136,8,169,246,154,319 | 1325,169,916,8,790,224,353,225,154,528,246,136,319 | -0.08385693476833972,1.937928245362595,0.19857493350037805,3.3336104827050863,0.3218233565713564,1.7008082712982846,1.1717250589049941,1.7008082712982846,2.0351905672615014,0.7196100272359108,1.635133356253012,2.1393434129981372,1.273799811880788 | 3,053 |
Snare interactions in vesicular transport | 8 | 13 | 2.903449 | 0.003691 | O95249,Q13190,Q9P2W9,O60499,O15400,Q86Y82,Q13277,Q9UNK0 | Processes and pathways | KEGG Pathways | msigdb_kegg | 224,225,136,8,169,246,154,319 | 1325,169,916,8,790,224,353,225,154,528,246,136,319 | -0.08385693476833972,1.937928245362595,0.19857493350037805,3.3336104827050863,0.3218233565713564,1.7008082712982846,1.1717250589049941,1.7008082712982846,2.0351905672615014,0.7196100272359108,1.635133356253012,2.1393434129981372,1.273799811880788 | 3,053 |
Antigen processing and presentation of peptide antigen | 7 | 13 | 2.900997 | 0.00372 | P10321,Q99538,Q9UIQ6,Q03518,P04439,Q9NZ08,Q9Y6B6 | Processes and pathways | GO Biological process | msigdb_gobp | 165,201,137,234,105,306,313 | 1230,325,105,165,2210,1430,1972,966,234,201,306,137,313 | -0.03128805197937675,1.2535436771356345,2.2835694069887835,1.9557428487590485,-0.511712584314456,-0.13699538899316593,-0.38355670174670764,0.16099777070340407,1.6727608132509426,1.8024087243316227,1.334102702134965,2.122122478433616,1.3040379142045533 | 3,053 |
Inorganic anion transmembrane transporter activity | 12 | 22 | 2.899944 | 0.003732 | P55011,Q9Y277,P45880,P51798,Q9Y6M7,Q9UBX3,P51790,Q9C0H2,P04920,Q4KMQ2,P21796,Q9H813 | Functions | GO Molecular function | msigdb_gomf | 390,251,135,269,403,113,239,19,275,244,151,89 | 2589,1595,275,1096,151,135,239,269,390,808,407,244,3005,2413,675,763,19,89,765,113,251,403 | -0.7483704240161151,-0.21780189519795196,1.4721773650526246,0.059377376010689153,2.0439466216934568,2.1393434129981372,1.6633788128540579,1.5109728694831275,1.0676115247162676,0.30963451704569495,1.0359660555856258,1.6445651501196628,-1.6857818609693211,-0.613809285254711,0.477640468160584,0.358212818135691,3.0342313533271863,2.3749098883187894,0.358212818135691,2.26679759515337,1.625684832355376,1.0465360280824727 | 3,053 |
Abnormality of corneal stroma | 7 | 17 | 2.890437 | 0.003847 | P04062,Q16625,P16278,P10619,P04114,P01130,O43505 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 288,134,73,141,144,188,220 | 220,188,288,144,141,73,696,1846,773,783,1099,950,865,318,134,2054,659 | 1.7194251000762824,1.866075878935031,1.3937211509001355,2.0788303063459717,2.096188534692145,2.4728566349196144,0.44210897675379346,-0.32767317867730517,0.34611234668124813,0.33398257941175047,0.059377376010689153,0.17355509404966507,0.2482403330382631,1.273799811880788,2.1479335171777034,-0.42589761215042704,0.512923337475363 | 3,053 |
Endoplasmic reticulum golgi intermediate compartment | 26 | 48 | 2.881398 | 0.003959 | P80303,P51572,Q8N511,Q9Y282,P07237,P24390,P53634,Q9H0U4,O95070,Q14789,Q10472,P49257,P33908,O15258,Q969X5,Q02818,Q9Y3B3,Q15904,P26572,P61019,P49755,Q13190,O15260,Q03518,Q12907,Q15363 | Localization | GO Cellular component | msigdb_gocc | 6,644,270,25,405,37,170,560,303,433,178,697,315,438,712,322,330,209,464,590,603,225,227,234,625,374 | 438,227,916,790,303,405,1754,37,464,1430,989,315,697,603,2453,644,2864,170,1410,590,6,322,234,178,625,225,433,1794,374,209,1578,883,1956,270,1297,1833,712,1065,560,1586,1198,1200,1530,25,1017,330,736,1251 | 0.9398515677513489,1.6914754779087535,0.19857493350037805,0.3218233565713564,1.334102702134965,1.0359660555856258,-0.2861796454358755,2.779747026833827,0.8965525637862654,-0.13699538899316593,0.14840860507849105,1.2939779145798287,0.44210897675379346,0.5943047502828036,-0.6433848115667744,0.5246297166579437,-1.0618618334058418,1.937928245362595,-0.12365661898489545,0.6173184799051494,3.409499537081338,1.2636815408562456,1.6727608132509426,1.9110956664873515,0.5595870981994009,1.7008082712982846,0.9613654253667215,-0.299971419663726,1.1095074471795692,1.765685690904278,-0.20424086935988572,0.23587033191152165,-0.3695251711327288,1.5109728694831275,-0.05750215436707501,-0.31380251320317754,0.43020921375824495,0.09772985746096338,0.674400725375824,-0.20424086935988572,-0.005212952459059928,-0.005212952459059928,-0.17723144136555438,2.953147342760977,0.13578741527968066,1.2433861353171847,0.3943400351131716,-0.03128805197937675 | 3,053 |
Corneal opacity | 22 | 56 | 2.880468 | 0.003971 | O75844,Q16625,P10619,P04114,Q99519,P53701,Q9H9S5,Q9NVI7,P04062,P40855,P04066,P06280,O00754,P01130,Q13510,P16278,Q6NUK1,O43505,P08236,P51648,O95202,Q9Y4P3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 130,134,141,144,148,277,158,417,288,291,43,45,181,188,318,73,332,220,241,118,249,384 | 181,2041,1746,1624,220,2534,1400,2797,610,512,130,1996,249,2043,188,2683,288,43,144,45,241,1375,141,73,696,1846,773,1925,291,783,118,1946,277,1099,2458,950,968,453,1087,865,1763,318,1010,1795,2779,134,332,2054,659,148,158,417,551,767,1028,384 | 1.9021217402473265,-0.42589761215042704,-0.2861796454358755,-0.2314007759263953,1.7194251000762824,-0.7030923807336273,-0.12365661898489545,-0.965598565884847,0.5827586084337831,0.7644222293835908,2.173622951248582,-0.3976291060973344,1.625684832355376,-0.42589761215042704,1.866075878935031,-0.824808688320819,1.3937211509001355,2.702652806647846,2.0788303063459717,2.6715150735890525,1.6539802803309698,-0.1103540999259057,2.096188534692145,2.4728566349196144,0.44210897675379346,-0.32767317867730517,0.34611234668124813,-0.35553424861853866,1.3838315350081463,0.33398257941175047,2.2415432585124297,-0.3695251711327288,1.4526723602880829,0.059377376010689153,-0.6433848115667744,0.17355509404966507,0.16099777070340407,0.9182475647792882,0.0721946227962857,0.2482403330382631,-0.2861796454358755,1.273799811880788,0.13578741527968066,-0.299971419663726,-0.9339456025039627,2.1479335171777034,1.2332088294189667,-0.42589761215042704,0.512923337475363,2.070130363883016,2.0088372660094183,1.01476116822825,0.685740711671661,0.358212818135691,0.1231340177911712,1.088601740735695 | 3,053 |
SNARE protein | 8 | 11 | 2.879879 | 0.003978 | O95249,Q13190,Q9P2W9,O60499,O15400,Q86Y82,Q13277,Q9UNK0 | Functions | Panther Protein class | panther_protein_class | 224,225,136,8,169,246,154,319 | 1325,169,8,224,353,225,154,528,246,136,319 | -0.08385693476833972,1.937928245362595,3.3336104827050863,1.7008082712982846,1.1717250589049941,1.7008082712982846,2.0351905672615014,0.7196100272359108,1.635133356253012,2.1393434129981372,1.273799811880788 | 3,053 |
SNARE protein | 8 | 11 | 2.879879 | 0.003978 | O95249,Q13190,Q9P2W9,O60499,O15400,Q86Y82,Q13277,Q9UNK0 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 224,225,136,8,169,246,154,319 | 1325,169,8,224,353,225,154,528,246,136,319 | -0.08385693476833972,1.937928245362595,3.3336104827050863,1.7008082712982846,1.1717250589049941,1.7008082712982846,2.0351905672615014,0.7196100272359108,1.635133356253012,2.1393434129981372,1.273799811880788 | 3,053 |
Chronic diarrhea | 8 | 18 | 2.873497 | 0.00406 | P02786,Q04656,P07686,Q15904,Q96J02,Q13277,Q96A33,Q13510 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 36,203,208,209,281,154,285,318 | 1230,2704,36,208,1375,696,2559,1117,203,797,154,318,1175,209,1906,285,281,396 | -0.03128805197937675,-0.8557335336316402,2.779747026833827,1.765685690904278,-0.1103540999259057,0.44210897675379346,-0.7181371319149215,0.0465267852872829,1.7840786381977862,0.3218233565713564,2.0351905672615014,1.273799811880788,0.007772986263866033,1.765685690904278,-0.34158367124160455,1.4134448616858115,1.433095060674533,1.0570844850930035 | 3,053 |
Divalent inorganic cation homeostasis | 20 | 50 | 2.869867 | 0.004106 | Q9HC07,P62942,Q15043,Q96TC7,Q96A33,P05067,Q8NEW0,Q16891,Q8IYU8,P0DP25,Q9BPX6,Q9HD20,P20020,P06756,P16615,P07686,Q7L0J3,Q8NE01,O76024,O95202 | Processes and pathways | GO Biological process | msigdb_gobp | 128,521,407,544,285,29,32,416,435,311,447,182,440,195,202,208,80,210,372,249 | 1229,1476,2617,372,249,1233,29,195,208,1374,1752,1754,311,1283,1234,202,548,440,1944,1430,2649,1409,644,1309,1151,521,1119,918,1979,1488,641,407,1011,416,2956,80,1901,435,210,1340,32,285,1439,544,447,128,182,927,1069,1278 | -0.03128805197937675,-0.16378257437491706,-0.7635596540122364,1.1095074471795692,1.625684832355376,-0.03128805197937675,2.8859295440854202,1.8297870381814723,1.765685690904278,-0.1103540999259057,-0.2861796454358755,-0.2861796454358755,1.3040379142045533,-0.05750215436707501,-0.03128805197937675,1.7932515087502272,0.685740711671661,0.9398515677513489,-0.3695251711327288,-0.13699538899316593,-0.7940850336780507,-0.12365661898489545,0.5246297166579437,-0.07066185389454786,0.020724788531935035,0.7420652759647238,0.0465267852872829,0.19857493350037805,-0.38355670174670764,-0.16378257437491706,0.5363090433704797,1.0359660555856258,0.13578741527968066,1.01476116822825,-1.3116133841257678,2.432256446318069,-0.34158367124160455,0.9613654253667215,1.765685690904278,-0.08385693476833972,2.8406681128013975,1.4134448616858115,-0.13699538899316593,0.6970555073651654,0.9398515677513489,2.18215929435381,1.9021217402473265,0.19857493350037805,0.09772985746096338,-0.044377623849349325 | 3,053 |
Abnormality of extrapyramidal motor function | 24 | 76 | 2.868321 | 0.004127 | O75569,Q13501,O96008,O00592,P07602,Q9H6K4,Q15043,P05067,P04062,Q99720,Q92673,Q9BPX6,O14949,O75787,P16278,P06865,P07686,P17900,Q6DKK2,Q9NZJ7,P35637,P12235,P11166,Q9Y4P3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 512,4,519,146,21,536,407,29,288,298,54,447,65,320,73,72,208,88,348,351,484,100,243,384 | 146,65,1328,1656,2178,512,320,1784,519,2536,288,29,1373,72,21,208,1753,243,1332,100,73,748,88,696,1846,2102,2900,2045,1925,2880,553,484,1409,2265,2378,1487,1853,931,2458,907,1513,950,2189,2435,970,4,1359,407,1010,2897,348,2054,1549,54,659,1245,1299,884,2994,298,447,1366,1647,536,1963,1395,351,766,2336,1028,862,1003,885,2342,384,1278 | 2.070130363883016,2.537203722894823,-0.08385693476833972,-0.24503774966773847,-0.49730329369665177,0.7644222293835908,1.2636815408562456,-0.299971419663726,0.7420652759647238,-0.7030923807336273,1.3937211509001355,2.8859295440854202,-0.1103540999259057,2.4728566349196144,3.0195749043603826,1.765685690904278,-0.2861796454358755,1.6445651501196628,-0.08385693476833972,2.308631386581677,2.4728566349196144,0.3702841521879034,2.3749098883187894,0.44210897675379346,-0.32767317867730517,-0.45433286929698796,-1.1436268388419184,-0.42589761215042704,-0.35553424861853866,-1.0943956937008812,0.674400725375824,0.830912855432633,-0.12365661898489545,-0.5406616335135016,-0.5990899607250865,-0.16378257437491706,-0.32767317867730517,0.18608075541134228,-0.6433848115667744,0.21103780546535914,-0.17723144136555438,0.17355509404966507,-0.49730329369665177,-0.6285741297543339,0.16099777070340407,3.430024135370345,-0.09708761132484221,1.0359660555856258,0.13578741527968066,-1.1271584702084125,1.2025574586113623,-0.42589761215042704,-0.19071746259586272,2.616602358730607,0.512923337475363,-0.03128805197937675,-0.05750215436707501,0.23587033191152165,-1.5757009117269876,1.363996390617815,0.9398515677513489,-0.09708761132484221,-0.2314007759263953,0.7083452377706503,-0.3695251711327288,-0.1103540999259057,1.192300224783089,0.358212818135691,-0.5697866191684537,0.1231340177911712,0.26057972136771734,0.14840860507849105,0.23587033191152165,-0.5697866191684537,1.088601740735695,-0.044377623849349325 | 3,053 |
Trans golgi network vesicle budding | 12 | 37 | 2.866701 | 0.004148 | P51809,Q92572,O43493,O75976,P02786,Q99523,P11717,P15586,P20645,P51148,P05067,O00115 | Processes and pathways | Reactome Pathways | msigdb_reactome | 353,420,3,99,36,77,109,184,312,406,29,61 | 61,1325,1229,2147,3,640,1533,942,99,36,29,1059,854,1922,109,184,312,966,406,353,663,1634,2213,968,728,1576,1822,1154,433,1860,1861,1297,420,77,2227,1564,1324 | 2.5690994296216365,-0.08385693476833972,-0.03128805197937675,-0.4829371027702765,3.585003342735257,0.5363090433704797,-0.19071746259586272,0.17355509404966507,2.308631386581677,2.779747026833827,2.8859295440854202,0.09772985746096338,0.26057972136771734,-0.35553424861853866,2.26679759515337,1.8841289535850934,1.3040379142045533,0.16099777070340407,1.0359660555856258,1.1717250589049941,0.501189764703237,-0.2314007759263953,-0.511712584314456,0.16099777070340407,0.3943400351131716,-0.20424086935988572,-0.31380251320317754,0.020724788531935035,0.9613654253667215,-0.32767317867730517,-0.32767317867730517,-0.05750215436707501,1.0041260536406191,2.4485323268593073,-0.511712584314456,-0.19071746259586272,-0.07066185389454786 | 3,053 |
Cherry red spot of the macula | 8 | 10 | 2.853449 | 0.004325 | P16278,P06865,P10619,P07686,Q99519,P07602,P17900,Q13510 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 73,72,141,208,148,21,88,318 | 72,21,208,141,2558,73,88,318,148,351 | 2.4728566349196144,3.0195749043603826,1.765685690904278,2.096188534692145,-0.7181371319149215,2.4728566349196144,2.3749098883187894,1.273799811880788,2.070130363883016,1.192300224783089 | 3,053 |
Rab geranylgeranylation | 14 | 18 | 2.849092 | 0.004384 | P20339,Q9BZG1,P61020,Q15286,P53611,Q9H0U4,Q14964,Q969Q5,P62820,P61019,P51149,P51148,Q9NP72,P51151 | Processes and pathways | Reactome Pathways | msigdb_reactome | 514,579,166,776,479,560,465,399,398,590,502,406,671,542 | 514,406,502,542,1149,479,590,166,795,1541,398,465,776,399,579,560,671,981 | 0.7644222293835908,1.0359660555856258,0.7866818484921456,0.6970555073651654,0.020724788531935035,0.8419112349230434,0.6173184799051494,1.9557428487590485,0.3218233565713564,-0.19071746259586272,1.0465360280824727,0.8965525637862654,0.34611234668124813,1.0465360280824727,0.6402283550178628,0.674400725375824,0.4894288560742516,0.16099777070340407 | 3,053 |
Inorganic ion transmembrane transport | 39 | 109 | 2.843196 | 0.004466 | Q9HC07,P55011,O75964,P62942,P05023,Q8N4V1,P05141,P51798,Q9Y6M7,Q7KZN9,P21796,Q8IUH4,Q15526,Q15043,Q96PU5,Q8IYU8,Q9UDW1,Q9HD20,P0DP25,Q9BPX6,P20020,P03915,P06756,Q13423,P08195,P16615,Q04656,P00403,Q92581,P54709,P12235,Q9UHG3,Q9UBX3,P51790,Q4KMQ2,O95202,O00400,P13073,P36543 | Processes and pathways | GO Biological process | msigdb_gobp | 128,390,260,521,394,267,395,269,403,143,151,279,408,407,287,435,183,182,311,447,440,439,195,197,328,202,203,463,214,480,100,235,113,239,244,249,508,380,381 | 508,1252,964,2617,2177,2178,1502,2753,1095,260,249,463,439,394,395,524,1687,195,2707,1374,1752,328,755,311,1628,1350,100,380,202,548,440,1097,1428,2735,2818,151,1148,2946,1944,2106,2649,2045,3034,1510,381,2107,1409,1256,2954,966,239,269,1086,480,390,598,1009,604,948,1151,521,1119,1637,918,808,203,1288,2435,1979,2621,1488,197,1462,407,408,244,2956,143,279,1901,435,1064,267,1340,214,2201,1772,1439,287,2994,926,447,1366,763,731,2944,1067,128,182,113,183,1200,235,1873,927,1069,2533,1278,403 | 0.7755641462351951,-0.044377623849349325,0.16099777070340407,-0.7635596540122364,-0.49730329369665177,-0.49730329369665177,-0.17723144136555438,-0.9181987971791161,0.059377376010689153,1.5494862574126163,1.625684832355376,0.8965525637862654,0.9398515677513489,1.0570844850930035,1.0570844850930035,0.7308499991523034,-0.2587130568814146,1.8297870381814723,-0.8557335336316402,-0.1103540999259057,-0.2861796454358755,1.2433861353171847,0.358212818135691,1.3040379142045533,-0.2314007759263953,-0.09708761132484221,2.308631386581677,1.088601740735695,1.7932515087502272,0.685740711671661,0.9398515677513489,0.059377376010689153,-0.13699538899316593,-0.8868625525092045,-0.9974667036146205,2.0439466216934568,0.020724788531935035,-1.277523820402273,-0.3695251711327288,-0.45433286929698796,-0.7940850336780507,-0.42589761215042704,-3.148782533062238,-0.17723144136555438,1.088601740735695,-0.45433286929698796,-0.12365661898489545,-0.044377623849349325,-1.3116133841257678,0.16099777070340407,1.6633788128540579,1.5109728694831275,0.0721946227962857,0.8419112349230434,1.0676115247162676,0.6058246629645279,0.13578741527968066,0.5943047502828036,0.17355509404966507,0.020724788531935035,0.7420652759647238,0.0465267852872829,-0.2314007759263953,0.19857493350037805,0.30963451704569495,1.7840786381977862,-0.05750215436707501,-0.6285741297543339,-0.38355670174670764,-0.7635596540122364,-0.16378257437491706,1.8206764297081328,-0.15037063254699395,1.0359660555856258,1.0359660555856258,1.6445651501196628,-1.3116133841257678,2.087516346686594,1.4526723602880829,-0.34158367124160455,0.9613654253667215,0.09772985746096338,1.5206274845608097,-0.08385693476833972,1.7472293962722831,-0.49730329369665177,-0.2861796454358755,-0.13699538899316593,1.4035922338561988,-1.5757009117269876,0.19857493350037805,0.9398515677513489,-0.09708761132484221,0.358212818135691,0.3943400351131716,-1.2605731068481651,0.09772985746096338,2.18215929435381,1.9021217402473265,2.26679759515337,1.9021217402473265,-0.005212952459059928,1.6727608132509426,-0.32767317867730517,0.19857493350037805,0.09772985746096338,-0.688095106410563,-0.044377623849349325,1.0465360280824727 | 3,053 |
Nucleobase containing compound transmembrane transporter activity | 10 | 14 | 2.839096 | 0.004524 | P12235,L0R6Q1,Q8TB61,P12236,P05141,Q9HC21,Q6NUK1,O00400,Q9H2D1,Q9BSK2 | Functions | GO Molecular function | msigdb_gomf | 100,511,68,103,395,299,332,508,92,95 | 511,508,538,395,100,103,1207,843,332,68,713,95,92,299 | 0.7644222293835908,0.7755641462351951,0.6970555073651654,1.0570844850930035,2.308631386581677,2.291936121589696,-0.018233230344920522,0.2728886665037662,1.2332088294189667,2.513161047727077,0.43020921375824495,2.3418704683845455,2.350148936285125,1.3540507039260963 | 3,053 |
Sphingolipid metabolism | 9 | 13 | 2.838497 | 0.004533 | P04062,P16278,P06280,Q8TCT0,O95470,Q99519,O15269,Q16739,Q13510 | Processes and pathways | KEGG Pathways | msigdb_kegg | 288,73,45,205,397,148,370,119,318 | 370,2233,1595,397,288,45,73,453,318,119,205,148,959 | 1.1095074471795692,-0.5261652660770593,-0.21780189519795196,1.0465360280824727,1.3937211509001355,2.6715150735890525,2.4728566349196144,0.9182475647792882,1.273799811880788,2.224642100818324,1.774890052445681,2.070130363883016,0.17355509404966507 | 3,053 |
Arteriosclerosis | 9 | 18 | 2.832091 | 0.004624 | O75844,O15118,P61916,P16278,P38435,P04114,Q99519,P01130,Q13510 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 130,164,261,73,237,144,148,188,318 | 164,2814,130,188,2683,144,73,696,1846,2595,773,237,329,261,318,1243,659,148 | 1.9557428487590485,-0.9974667036146205,2.173622951248582,1.866075878935031,-0.824808688320819,2.0788303063459717,2.4728566349196144,0.44210897675379346,-0.32767317867730517,-0.7483704240161151,0.34611234668124813,1.6633788128540579,1.2433861353171847,1.5494862574126163,1.273799811880788,-0.03128805197937675,0.512923337475363,2.070130363883016 | 3,053 |
Cholesterol binding | 6 | 12 | 2.822473 | 0.004765 | O15118,P45880,Q14849,Q14108,P21796,O95772 | Functions | GO Molecular function | msigdb_gomf | 164,135,49,213,151,124 | 164,1185,124,1752,151,2429,553,135,261,213,49,1247 | 1.9557428487590485,-0.005212952459059928,2.1906823149730266,-0.2861796454358755,2.0439466216934568,-0.6285741297543339,0.674400725375824,2.1393434129981372,1.5494862574126163,1.7472293962722831,2.6480472532459483,-0.03128805197937675 | 3,053 |
Cargo recognition for clathrin mediated endocytosis | 13 | 34 | 2.81837 | 0.004827 | O14657,P51809,O43493,P98164,P02786,Q99627,P00533,P11717,P04114,Q14108,Q9BT78,P20645,P01130 | Processes and pathways | Reactome Pathways | msigdb_reactome | 379,353,3,196,36,376,335,109,144,213,218,312,188 | 379,3,2369,1451,335,188,36,144,1059,854,109,312,2619,353,946,828,1287,1761,196,2213,2320,1576,213,1800,1861,860,1181,636,2057,376,2088,218,851,388 | 1.088601740735695,3.585003342735257,-0.5990899607250865,-0.15037063254699395,1.2230116728735583,1.866075878935031,2.779747026833827,2.0788303063459717,0.09772985746096338,0.26057972136771734,2.26679759515337,1.3040379142045533,-0.7635596540122364,1.1717250589049941,0.17355509404966507,0.28516733659390786,-0.05750215436707501,-0.2861796454358755,1.8297870381814723,-0.511712584314456,-0.5697866191684537,-0.20424086935988572,1.7472293962722831,-0.299971419663726,-0.32767317867730517,0.26057972136771734,0.007772986263866033,0.5479614575971996,-0.42589761215042704,1.099065109888305,-0.4400942588347924,1.737977340170717,0.2728886665037662,1.0781172443576843 | 3,053 |
Entry into host | 18 | 36 | 2.814817 | 0.00488 | Q9Y624,P11279,P06756,O15118,P02786,P35613,Q8WTV0,P08195,Q92692,P00533,P15529,P01130,Q9BTY2,P07237,Q14108,Q96J02,P07858,O14786 | Processes and pathways | GO Biological process | msigdb_gobp | 352,121,195,164,36,229,359,328,473,335,236,188,84,405,213,281,27,412 | 1594,412,164,1232,335,188,36,524,1372,195,405,27,328,1403,2179,121,2210,236,2808,2619,2518,229,2351,774,1189,213,1153,613,359,473,281,1270,84,1714,653,352 | -0.21780189519795196,1.025374468803066,1.9557428487590485,-0.03128805197937675,1.2230116728735583,1.866075878935031,2.779747026833827,0.7308499991523034,-0.1103540999259057,1.8297870381814723,1.0359660555856258,2.9233715788819468,1.2433861353171847,-0.12365661898489545,-0.49730329369665177,2.2161719066574945,-0.511712584314456,1.6633788128540579,-0.9815055327487577,-0.7635596540122364,-0.688095106410563,1.6914754779087535,-0.5844158422252788,0.34611234668124813,-0.005212952459059928,1.7472293962722831,0.020724788531935035,0.5827586084337831,1.1510683617802193,0.8638375447218682,1.433095060674533,-0.044377623849349325,2.4077523196496067,-0.2587130568814146,0.5246297166579437,1.192300224783089 | 3,053 |
Cell surface interactions at the vascular wall | 9 | 16 | 2.802854 | 0.005065 | P54709,Q9UNN8,Q9Y624,P35613,P06756,P08195,Q92896,Q08722,P04114 | Processes and pathways | Reactome Pathways | msigdb_reactome | 480,129,352,229,195,328,111,140,144 | 144,524,195,1374,328,842,229,819,480,1287,774,2192,140,111,129,352 | 2.0788303063459717,0.7308499991523034,1.8297870381814723,-0.1103540999259057,1.2433861353171847,0.2728886665037662,1.6914754779087535,0.2974158983461496,0.8419112349230434,-0.05750215436707501,0.34611234668124813,-0.49730329369665177,2.1048469198732267,2.26679759515337,2.18215929435381,1.192300224783089 | 3,053 |
Glucose import | 6 | 13 | 2.799618 | 0.005116 | P52789,Q16625,Q06481,Q99523,P11166,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 257,134,74,77,243,254 | 680,243,301,1568,254,1257,257,2192,74,134,1953,77,1247 | 0.4658244563610143,1.6445651501196628,1.3440861679024063,-0.20424086935988572,1.5877220944504011,-0.044377623849349325,1.5686385889352172,-0.49730329369665177,2.4566523252294235,2.1479335171777034,-0.3695251711327288,2.4485323268593073,-0.03128805197937675 | 3,053 |
Antiport | 7 | 9 | 2.797916 | 0.005143 | P12235,P12236,P51798,P51790,P04920,Q92581,O95202 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 100,103,269,239,275,214,249 | 249,275,395,100,103,1207,239,269,214 | 1.625684832355376,1.4721773650526246,1.0570844850930035,2.308631386581677,2.291936121589696,-0.018233230344920522,1.6633788128540579,1.5109728694831275,1.7472293962722831 | 3,053 |
Voltage gated channel activity | 6 | 11 | 2.796218 | 0.00517 | P06756,P45880,P51790,Q4KMQ2,P21796,Q9Y277 | Functions | GO Molecular function | msigdb_gomf | 195,135,239,244,151,251 | 2589,195,1096,151,135,239,269,918,244,1613,251 | -0.7483704240161151,1.8297870381814723,0.059377376010689153,2.0439466216934568,2.1393434129981372,1.6633788128540579,1.5109728694831275,0.19857493350037805,1.6445651501196628,-0.21780189519795196,1.625684832355376 | 3,053 |
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