term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synaptic vesicle membrane | 11 | 15 | 2.792683 | 0.005227 | P20339,P61020,O60499,O15126,O43760,Q7L0J3,O76024,Q86Y82,P0DP25,P51149,P20020 | Localization | GO Cellular component | msigdb_gocc | 514,166,8,582,358,80,372,246,311,502,440 | 622,582,358,8,372,1059,854,311,440,514,502,166,776,80,246 | 0.5595870981994009,0.6287863334786191,1.1510683617802193,3.3336104827050863,1.1095074471795692,0.09772985746096338,0.26057972136771734,1.3040379142045533,0.9398515677513489,0.7644222293835908,0.7866818484921456,1.9557428487590485,0.34611234668124813,2.432256446318069,1.635133356253012 | 3,053 |
Amyloid precursor protein catabolic process | 9 | 18 | 2.788925 | 0.005288 | Q15392,P62942,O95197,Q92542,Q14254,Q92673,P15260,Q9NQC3,Q96P70 | Processes and pathways | GO Biological process | msigdb_gobp | 515,521,42,206,432,54,22,60,159 | 1006,42,1374,22,1944,1849,603,1257,521,1576,1543,432,515,206,54,159,2465,60 | 0.13578741527968066,2.702652806647846,-0.1103540999259057,3.004880449945332,-0.3695251711327288,-0.32767317867730517,0.5943047502828036,-0.044377623849349325,0.7420652759647238,-0.20424086935988572,-0.19071746259586272,0.9613654253667215,0.7644222293835908,1.774890052445681,2.616602358730607,1.991196931629869,-0.6433848115667744,2.577044818596751 | 3,053 |
Protein targeting | 27 | 102 | 2.785965 | 0.005337 | Q9NS69,Q8N4H5,O96008,O60830,O60725,Q9Y512,Q9P0J0,Q99595,Q9Y5M8,P40855,P43307,O00560,O14925,O95831,Q92673,P20645,P33908,Q9H9H4,Q99523,Q15005,Q14108,Q15629,P55786,Q3ZCQ8,P57105,P51149,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 1,5,519,10,272,531,400,30,290,291,38,168,173,304,54,312,315,450,77,337,213,217,233,491,503,502,254 | 1744,1229,168,1476,1072,173,1328,985,1595,1369,272,10,610,2753,1115,1423,2149,840,1811,304,519,1921,1535,2914,1922,2259,312,1429,1944,2373,254,1431,315,2315,2136,291,38,1432,697,1020,1257,783,502,644,233,503,2964,698,2138,948,2109,1151,2599,1887,2524,918,951,1488,213,337,690,217,2412,866,491,571,1266,1670,2638,1135,1491,2484,922,2297,5,832,54,535,884,77,30,823,1646,450,2276,1,1871,400,2062,900,1182,1200,2035,2063,2128,940,1531,1276,1915,531,769,290 | -0.2861796454358755,-0.03128805197937675,1.937928245362595,-0.16378257437491706,0.0849787193065716,1.9289988637379116,-0.08385693476833972,0.14840860507849105,-0.21780189519795196,-0.1103540999259057,1.501300622699395,3.2637394965616733,0.5827586084337831,-0.9181987971791161,0.0465267852872829,-0.13699538899316593,-0.4829371027702765,0.2728886665037662,-0.31380251320317754,1.334102702134965,0.7420652759647238,-0.35553424861853866,-0.19071746259586272,-1.1767398600294696,-0.35553424861853866,-0.5406616335135016,1.3040379142045533,-0.13699538899316593,-0.3695251711327288,-0.5990899607250865,1.5877220944504011,-0.13699538899316593,1.2939779145798287,-0.5697866191684537,-0.4686137231142239,1.3838315350081463,2.749036603520299,-0.13699538899316593,0.44210897675379346,0.1231340177911712,-0.044377623849349325,0.33398257941175047,0.7866818484921456,0.5246297166579437,1.6727608132509426,0.7866818484921456,-1.3459573008332442,0.44210897675379346,-0.4686137231142239,0.17355509404966507,-0.45433286929698796,0.020724788531935035,-0.7483704240161151,-0.34158367124160455,-0.688095106410563,0.19857493350037805,0.17355509404966507,-0.16378257437491706,1.7472293962722831,1.2230116728735583,0.4539806748878796,1.737977340170717,-0.613809285254711,0.2482403330382631,0.8088450797618966,0.6516446748258692,-0.044377623849349325,-0.24503774966773847,-0.7787977391346896,0.03364265519892447,-0.16378257437491706,-0.6582416514877483,0.19857493350037805,-0.5552019842727006,3.4231907179791325,0.28516733659390786,2.616602358730607,0.7083452377706503,0.23587033191152165,2.4485323268593073,2.863344325148585,0.2974158983461496,-0.2314007759263953,0.9290608874339265,-0.5406616335135016,3.6708025762594803,-0.32767317867730517,1.0465360280824727,-0.42589761215042704,0.22346954691003423,0.007772986263866033,-0.005212952459059928,-0.41174265253282316,-0.42589761215042704,-0.45433286929698796,0.18608075541134228,-0.17723144136555438,-0.044377623849349325,-0.34158367124160455,0.7196100272359108,0.358212818135691,1.3937211509001355 | 3,053 |
Anion channel activity | 7 | 13 | 2.78239 | 0.005396 | Q9H813,P45880,P51790,Q9C0H2,Q4KMQ2,P21796,Q9Y277 | Functions | GO Molecular function | msigdb_gomf | 89,135,239,19,244,151,251 | 2589,1096,151,135,239,269,244,2413,675,19,89,765,251 | -0.7483704240161151,0.059377376010689153,2.0439466216934568,2.1393434129981372,1.6633788128540579,1.5109728694831275,1.6445651501196628,-0.613809285254711,0.477640468160584,3.0342313533271863,2.3749098883187894,0.358212818135691,1.625684832355376 | 3,053 |
Protein catabolic process in the vacuole | 6 | 8 | 2.781308 | 0.005414 | P04062,P98164,Q8N511,Q07954,O14773,P01130 | Processes and pathways | GO Biological process | msigdb_gobp | 288,196,270,110,108,188 | 108,188,288,196,110,270,296,1299 | 2.26679759515337,1.866075878935031,1.3937211509001355,1.8297870381814723,2.26679759515337,1.5109728694831275,1.373923307859532,-0.05750215436707501 | 3,053 |
Lysosomal protein catabolic process | 6 | 8 | 2.781308 | 0.005414 | P04062,P98164,Q8N511,Q07954,O14773,P01130 | Processes and pathways | GO Biological process | msigdb_gobp | 288,196,270,110,108,188 | 108,188,288,196,110,270,296,1299 | 2.26679759515337,1.866075878935031,1.3937211509001355,1.8297870381814723,2.26679759515337,1.5109728694831275,1.373923307859532,-0.05750215436707501 | 3,053 |
EGF-like calcium-binding domain [IPR001881] | 6 | 7 | 2.780128 | 0.005434 | P98164,P48960,P98155,Q07954,P14543,P01130 | Sequence | InterPro Domain | interpro_domain | 196,102,40,110,123,188 | 207,188,123,102,40,196,110 | 1.765685690904278,1.866075878935031,2.199192059706801,2.300290100303094,2.7181568448827473,1.8297870381814723,2.26679759515337 | 3,053 |
EGF-like calcium-binding, conserved site [IPR018097] | 6 | 7 | 2.780128 | 0.005434 | P98164,P48960,P98155,Q07954,P14543,P01130 | Sequence | InterPro Conserved site | interpro_conserved_site | 196,102,40,110,123,188 | 207,188,123,102,40,196,110 | 1.765685690904278,1.866075878935031,2.199192059706801,2.300290100303094,2.7181568448827473,1.8297870381814723,2.26679759515337 | 3,053 |
EGF-type aspartate/asparagine hydroxylation site [IPR000152] | 6 | 7 | 2.780128 | 0.005434 | P98164,P48960,P98155,Q07954,P14543,P01130 | Sequence | InterPro PTM | interpro_ptm | 196,102,40,110,123,188 | 207,188,123,102,40,196,110 | 1.765685690904278,1.866075878935031,2.199192059706801,2.300290100303094,2.7181568448827473,1.8297870381814723,2.26679759515337 | 3,053 |
Regulation of vesicle mediated transport | 41 | 116 | 2.780089 | 0.005434 | P20339,P09601,Q9P2W9,Q08722,Q08431,P51148,Q9NR31,P05067,Q96PU5,P51151,O14786,P61020,O00560,P50897,Q92673,P0DP25,Q9Y6B6,P06756,Q15042,Q06481,P16615,P04899,P49815,Q9HCU5,P11233,P51809,Q9H223,Q8WTV0,Q8WUM4,Q9H4M9,O75955,P57105,Q6NUQ1,Q07954,Q12907,Q4KMQ2,P31751,P11279,P51149,Q96CW1,Q4J6C6 | Processes and pathways | GO Biological process | msigdb_gobp | 514,133,136,140,278,406,284,29,287,542,412,166,168,53,54,311,313,195,326,74,202,587,597,470,253,353,357,359,616,377,363,503,366,110,625,244,254,121,502,636,635 | 680,1938,168,412,640,1533,1596,1232,1843,1656,2100,2885,363,1081,2985,587,29,195,2707,1374,1754,133,311,253,121,2182,202,2788,781,514,2619,2104,2105,1944,1430,1507,989,254,1882,1883,2374,1207,1036,597,966,53,406,502,542,1149,353,2760,946,503,1817,166,795,1061,1662,1208,1761,1820,918,1152,74,2435,110,2318,1514,278,140,625,1576,2497,1358,1264,656,326,1011,635,244,366,1491,2947,922,2029,1137,1295,359,616,1493,54,860,1906,636,287,1555,849,357,1559,377,470,726,284,1871,2805,1714,1966,136,980,981,2128,1529,789,852,313 | 0.4658244563610143,-0.3695251711327288,1.937928245362595,1.025374468803066,0.5363090433704797,-0.19071746259586272,-0.21780189519795196,-0.03128805197937675,-0.32767317867730517,-0.24503774966773847,-0.45433286929698796,-1.1107482414651932,1.1303294043028353,0.0721946227962857,-1.5037706134431923,0.6173184799051494,2.8859295440854202,1.8297870381814723,-0.8557335336316402,-0.1103540999259057,-0.2861796454358755,2.1479335171777034,1.3040379142045533,1.6067373269013259,2.2161719066574945,-0.49730329369665177,1.7932515087502272,-0.9497453913983102,0.33398257941175047,0.7644222293835908,-0.7635596540122364,-0.45433286929698796,-0.45433286929698796,-0.3695251711327288,-0.13699538899316593,-0.17723144136555438,0.14840860507849105,1.5877220944504011,-0.34158367124160455,-0.34158367124160455,-0.5990899607250865,-0.018233230344920522,0.11044822745697883,0.6058246629645279,0.16099777070340407,2.616602358730607,1.0359660555856258,0.7866818484921456,0.6970555073651654,0.020724788531935035,1.1717250589049941,-0.9181987971791161,0.17355509404966507,0.7866818484921456,-0.31380251320317754,1.9557428487590485,0.3218233565713564,0.09772985746096338,-0.24503774966773847,-0.018233230344920522,-0.2861796454358755,-0.31380251320317754,0.19857493350037805,0.020724788531935035,2.4566523252294235,-0.6285741297543339,2.26679759515337,-0.5697866191684537,-0.17723144136555438,1.4526723602880829,2.1048469198732267,0.5595870981994009,-0.20424086935988572,-0.6731449738170256,-0.09708761132484221,-0.044377623849349325,0.512923337475363,1.2535436771356345,0.13578741527968066,0.5479614575971996,1.6445651501196628,1.1199288473059854,-0.16378257437491706,-1.277523820402273,0.19857493350037805,-0.41174265253282316,0.03364265519892447,-0.05750215436707501,1.1510683617802193,0.5827586084337831,-0.16378257437491706,2.616602358730607,0.26057972136771734,-0.34158367124160455,0.5479614575971996,1.4035922338561988,-0.19071746259586272,0.2728886665037662,1.1614069470810378,-0.19071746259586272,1.099065109888305,0.8747656995030354,0.40632489423308854,1.423279111691743,-0.32767317867730517,-0.965598565884847,-0.2587130568814146,-0.3695251711327288,2.1393434129981372,0.16099777070340407,0.16099777070340407,-0.45433286929698796,-0.17723144136555438,0.33398257941175047,0.2728886665037662,1.3040379142045533 | 3,053 |
Abnormality of femur morphology | 25 | 68 | 2.779342 | 0.005447 | O75844,P55011,P51798,P07602,P15260,Q7LGA3,Q96A33,P04062,P04066,P06280,O95831,Q9Y619,O00754,Q9BXW9,Q9UHX1,P16278,Q04656,Q96HY6,Q9NZJ7,Q14739,Q9Y487,Q9BV10,Q6NUQ1,P16435,Q8WVQ1 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 130,390,269,21,22,24,285,288,43,45,304,180,181,456,69,73,203,349,351,355,360,231,366,373,247 | 1145,2147,1623,181,2041,2176,2797,780,2101,816,130,2257,304,2017,2683,288,43,1920,45,21,22,73,373,2818,2153,1507,2283,2969,2918,1600,783,269,2137,2454,390,2138,203,355,1411,1668,628,1361,366,2980,24,461,2272,997,1801,247,659,285,1046,349,870,1271,231,456,1559,2794,837,2392,351,69,2509,360,2067,180 | 0.020724788531935035,-0.4829371027702765,-0.2314007759263953,1.9021217402473265,-0.42589761215042704,-0.49730329369665177,-0.965598565884847,0.33398257941175047,-0.45433286929698796,0.2974158983461496,2.173622951248582,-0.5406616335135016,1.334102702134965,-0.41174265253282316,-0.824808688320819,1.3937211509001355,2.702652806647846,-0.35553424861853866,2.6715150735890525,3.0195749043603826,3.004880449945332,2.4728566349196144,1.1095074471795692,-0.9974667036146205,-0.4829371027702765,-0.17723144136555438,-0.5552019842727006,-1.363225981446116,-1.1767398600294696,-0.21780189519795196,0.33398257941175047,1.5109728694831275,-0.4686137231142239,-0.6433848115667744,1.0676115247162676,-0.4686137231142239,1.7840786381977862,1.1717250589049941,-0.12365661898489545,-0.24503774966773847,0.5595870981994009,-0.09708761132484221,1.1199288473059854,-1.4329583992749886,2.9679765780397287,0.9074114928163481,-0.5406616335135016,0.14840860507849105,-0.299971419663726,1.635133356253012,0.512923337475363,1.4134448616858115,0.11044822745697883,1.2025574586113623,0.2482403330382631,-0.044377623849349325,1.6821263466818883,0.9182475647792882,-0.19071746259586272,-0.9497453913983102,0.28516733659390786,-0.5990899607250865,1.192300224783089,2.497074466074281,-0.6731449738170256,1.1510683617802193,-0.42589761215042704,1.9110956664873515 | 3,053 |
Vacuole organization | 26 | 51 | 2.774182 | 0.005534 | Q9HC07,P20339,Q6IAA8,Q9Y4P8,Q8N511,P62820,P54802,P04062,Q8NHS3,Q9H0U4,P42345,P50897,Q9P0T7,Q9BZG1,O75787,Q15042,P16615,P07686,Q14964,P11117,Q14108,P10253,O75503,O14773,Q86Y82,P51149 | Processes and pathways | GO Biological process | msigdb_gobp | 128,514,386,518,270,398,160,288,296,560,554,53,64,579,320,326,202,208,465,83,213,93,104,108,246,502 | 1229,108,790,104,320,2697,1811,288,2707,208,93,83,695,202,514,554,1117,53,502,160,1540,1541,398,213,465,326,776,593,386,246,270,296,1493,760,1773,1299,579,560,937,128,1871,3032,64,1714,2128,1111,1003,1276,789,718,518 | -0.03128805197937675,2.26679759515337,0.3218233565713564,2.2835694069887835,1.2636815408562456,-0.8402457773111607,-0.31380251320317754,1.3937211509001355,-0.8557335336316402,1.765685690904278,2.3418704683845455,2.4077523196496067,0.44210897675379346,1.7932515087502272,0.7644222293835908,0.674400725375824,0.0465267852872829,2.616602358730607,0.7866818484921456,1.9823551672513169,-0.19071746259586272,-0.19071746259586272,1.0465360280824727,1.7472293962722831,0.8965525637862654,1.2535436771356345,0.34611234668124813,0.6173184799051494,1.0781172443576843,1.635133356253012,1.5109728694831275,1.373923307859532,-0.16378257437491706,0.358212818135691,-0.2861796454358755,-0.05750215436707501,0.6402283550178628,0.674400725375824,0.18608075541134228,2.18215929435381,-0.32767317867730517,-3.0205793937440046,2.553174480013193,-0.2587130568814146,-0.45433286929698796,0.059377376010689153,0.14840860507849105,-0.044377623849349325,0.33398257941175047,0.4182812364739646,0.7532559791813919 | 3,053 |
Golgi cisterna membrane | 9 | 17 | 2.774159 | 0.005534 | Q8NBZ7,Q9H4A5,Q99523,Q10471,Q8NBN3,Q10472,Q8WVQ1,Q9Y6B6,O00461 | Localization | GO Cellular component | msigdb_gocc | 258,167,77,331,47,178,247,313,120 | 120,1096,644,3022,331,178,951,374,47,258,1493,247,870,77,167,981,313 | 2.2161719066574945,0.059377376010689153,0.5246297166579437,-2.196785358451848,1.2332088294189667,1.9110956664873515,0.17355509404966507,1.1095074471795692,2.663703430679951,1.5686385889352172,-0.16378257437491706,1.635133356253012,0.2482403330382631,2.4485323268593073,1.9468428888650193,0.16099777070340407,1.3040379142045533 | 3,053 |
Golgi vesicle transport | 44 | 118 | 2.772575 | 0.005561 | O43731,O60499,Q9P2W9,P51572,P62820,O15127,O00743,P54920,Q9Y282,Q9NR31,P40616,Q92572,P24390,Q9H4A5,Q6DD88,Q9H0U4,O95070,Q92673,P49257,Q9Y6B6,Q9UID3,O15258,Q8TBA6,Q969X5,Q9BZG1,O15126,Q9Y3B3,Q99523,P61019,Q9HD26,Q9HCU5,P49755,O95249,Q13190,P51809,O15260,O60826,Q6NUQ1,Q12907,Q15363,O14828,P11279,Q8NHH9,Q4J6C6 | Processes and pathways | GO Biological process | msigdb_gobp | 0,8,136,644,398,147,662,663,25,284,667,420,37,167,426,560,303,54,697,313,573,438,577,712,579,582,330,77,590,726,470,603,224,225,353,227,617,366,625,374,369,121,383,635 | 1325,2750,662,1716,1476,369,1326,582,147,438,227,916,2742,0,1533,1281,1232,8,942,1879,617,943,790,2885,1598,303,224,1233,1450,2590,1081,1451,121,756,37,793,2560,667,2374,1409,1036,1600,855,697,603,966,1149,644,353,2864,2266,2455,663,1487,2522,1540,590,795,1541,1571,398,1820,2434,1821,625,1488,225,1382,2026,1191,1011,374,1605,635,972,426,366,1933,883,1956,2297,383,577,1493,1297,420,54,1121,712,869,1270,77,1090,1065,579,560,167,1525,470,726,284,2277,1966,136,1198,2572,1682,573,1052,1937,25,2145,1017,330,1474,736,313,1251 | -0.08385693476833972,-0.9181987971791161,0.501189764703237,-0.27242694039497706,-0.16378257437491706,1.1095074471795692,-0.08385693476833972,0.6287863334786191,2.070130363883016,0.9398515677513489,1.6914754779087535,0.19857493350037805,-0.9025045780882558,3.7488958239943146,-0.19071746259586272,-0.05750215436707501,-0.03128805197937675,3.3336104827050863,0.17355509404966507,-0.34158367124160455,0.571186102927646,0.17355509404966507,0.3218233565713564,-1.1107482414651932,-0.21780189519795196,1.334102702134965,1.7008082712982846,-0.03128805197937675,-0.15037063254699395,-0.7483704240161151,0.0721946227962857,-0.15037063254699395,2.2161719066574945,0.358212818135691,2.779747026833827,0.3218233565713564,-0.7181371319149215,0.4894288560742516,-0.5990899607250865,-0.12365661898489545,0.11044822745697883,-0.21780189519795196,0.26057972136771734,0.44210897675379346,0.5943047502828036,0.16099777070340407,0.020724788531935035,0.5246297166579437,1.1717250589049941,-1.0618618334058418,-0.5406616335135016,-0.6433848115667744,0.501189764703237,-0.16378257437491706,-0.688095106410563,-0.19071746259586272,0.6173184799051494,0.3218233565713564,-0.19071746259586272,-0.20424086935988572,1.0465360280824727,-0.31380251320317754,-0.6285741297543339,-0.31380251320317754,0.5595870981994009,-0.16378257437491706,1.7008082712982846,-0.1103540999259057,-0.41174265253282316,-0.005212952459059928,0.13578741527968066,1.1095074471795692,-0.21780189519795196,0.5479614575971996,0.16099777070340407,0.9827899779325561,1.1199288473059854,-0.35553424861853866,0.23587033191152165,-0.3695251711327288,-0.5552019842727006,1.088601740735695,0.6402283550178628,-0.16378257437491706,-0.05750215436707501,1.0041260536406191,2.616602358730607,0.0465267852872829,0.43020921375824495,0.2482403330382631,-0.044377623849349325,2.4485323268593073,0.0721946227962857,0.09772985746096338,0.6402283550178628,0.674400725375824,1.9468428888650193,-0.17723144136555438,0.8747656995030354,0.40632489423308854,1.423279111691743,-0.5406616335135016,-0.3695251711327288,2.1393434129981372,-0.005212952459059928,-0.7181371319149215,-0.24503774966773847,0.6516446748258692,0.11044822745697883,-0.35553424861853866,2.953147342760977,-0.4686137231142239,0.13578741527968066,1.2433861353171847,-0.15037063254699395,0.3943400351131716,1.3040379142045533,-0.03128805197937675 | 3,053 |
Bulbar signs | 7 | 13 | 2.770114 | 0.005604 | P04062,Q9NZJ7,Q99720,P07602,Q15043,P03886,P03915 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 288,351,298,21,407,316,439 | 1595,316,439,288,1373,21,484,1129,407,1121,298,351,885 | -0.21780189519795196,1.2838985750362097,0.9398515677513489,1.3937211509001355,-0.1103540999259057,3.0195749043603826,0.830912855432633,0.03364265519892447,1.0359660555856258,0.0465267852872829,1.363996390617815,1.192300224783089,0.23587033191152165 | 3,053 |
Cation transmembrane transport | 42 | 118 | 2.769778 | 0.005609 | Q9HC07,P55011,O75964,P62942,Q70HW3,Q8N4V1,P05141,P05023,Q9Y6M7,Q7KZN9,P21796,Q8IUH4,Q15526,Q15043,P05067,Q96PU5,Q8NEW0,Q9HC21,Q8IYU8,Q9Y619,Q9UDW1,Q9HD20,P0DP25,Q9BPX6,P20020,P03915,P06756,Q13423,P08195,P16615,Q04656,P30825,P00403,Q92581,P54709,P12235,P51790,Q4KMQ2,O95202,O00400,P13073,P36543 | Processes and pathways | GO Biological process | msigdb_gobp | 128,390,260,521,266,267,395,394,403,143,151,279,408,407,29,287,32,299,435,180,183,182,311,447,440,439,195,197,328,202,203,79,463,214,480,100,239,244,249,508,380,381 | 508,1252,964,3007,2617,2177,2178,1502,2753,1095,260,249,463,439,394,29,395,524,1687,195,2707,2235,1374,1752,328,755,311,1628,1350,100,380,202,548,440,1097,1428,2735,2818,151,1148,2946,1944,2106,2649,79,2045,3034,1510,381,2107,1409,1256,2954,966,239,1086,480,390,598,1009,604,948,1151,521,1119,1637,918,203,1288,2435,1979,2621,1488,197,1462,407,1011,408,613,244,2956,266,143,279,1901,435,1064,267,1340,32,214,2201,1772,1439,1674,287,2994,926,447,1366,763,731,2944,1067,652,128,299,182,765,183,1200,1873,927,1069,2533,1278,180,403 | 0.7755641462351951,-0.044377623849349325,0.16099777070340407,-1.7418453203119433,-0.7635596540122364,-0.49730329369665177,-0.49730329369665177,-0.17723144136555438,-0.9181987971791161,0.059377376010689153,1.5494862574126163,1.625684832355376,0.8965525637862654,0.9398515677513489,1.0570844850930035,2.8859295440854202,1.0570844850930035,0.7308499991523034,-0.2587130568814146,1.8297870381814723,-0.8557335336316402,-0.5261652660770593,-0.1103540999259057,-0.2861796454358755,1.2433861353171847,0.358212818135691,1.3040379142045533,-0.2314007759263953,-0.09708761132484221,2.308631386581677,1.088601740735695,1.7932515087502272,0.685740711671661,0.9398515677513489,0.059377376010689153,-0.13699538899316593,-0.8868625525092045,-0.9974667036146205,2.0439466216934568,0.020724788531935035,-1.277523820402273,-0.3695251711327288,-0.45433286929698796,-0.7940850336780507,2.432256446318069,-0.42589761215042704,-3.148782533062238,-0.17723144136555438,1.088601740735695,-0.45433286929698796,-0.12365661898489545,-0.044377623849349325,-1.3116133841257678,0.16099777070340407,1.6633788128540579,0.0721946227962857,0.8419112349230434,1.0676115247162676,0.6058246629645279,0.13578741527968066,0.5943047502828036,0.17355509404966507,0.020724788531935035,0.7420652759647238,0.0465267852872829,-0.2314007759263953,0.19857493350037805,1.7840786381977862,-0.05750215436707501,-0.6285741297543339,-0.38355670174670764,-0.7635596540122364,-0.16378257437491706,1.8206764297081328,-0.15037063254699395,1.0359660555856258,0.13578741527968066,1.0359660555856258,0.5827586084337831,1.6445651501196628,-1.3116133841257678,1.5206274845608097,2.087516346686594,1.4526723602880829,-0.34158367124160455,0.9613654253667215,0.09772985746096338,1.5206274845608097,-0.08385693476833972,2.8406681128013975,1.7472293962722831,-0.49730329369665177,-0.2861796454358755,-0.13699538899316593,-0.24503774966773847,1.4035922338561988,-1.5757009117269876,0.19857493350037805,0.9398515677513489,-0.09708761132484221,0.358212818135691,0.3943400351131716,-1.2605731068481651,0.09772985746096338,0.5246297166579437,2.18215929435381,1.3540507039260963,1.9021217402473265,0.358212818135691,1.9021217402473265,-0.005212952459059928,-0.32767317867730517,0.19857493350037805,0.09772985746096338,-0.688095106410563,-0.044377623849349325,1.9110956664873515,1.0465360280824727 | 3,053 |
Nucleotide transport | 10 | 14 | 2.766255 | 0.00567 | P12235,Q8TB61,P12236,P05141,Q9HC21,Q6NUK1,Q08722,O00400,Q9H2D1,Q9BSK2 | Processes and pathways | GO Biological process | msigdb_gobp | 100,68,103,395,299,332,140,508,92,95 | 508,538,395,100,103,1207,140,2413,332,68,713,95,92,299 | 0.7755641462351951,0.6970555073651654,1.0570844850930035,2.308631386581677,2.291936121589696,-0.018233230344920522,2.1048469198732267,-0.613809285254711,1.2332088294189667,2.513161047727077,0.43020921375824495,2.3418704683845455,2.350148936285125,1.3540507039260963 | 3,053 |
Membrane lipid biosynthetic process | 14 | 25 | 2.762491 | 0.005736 | P04062,Q8NBX0,Q9P035,Q9H490,Q06136,Q96G23,O43292,O95470,Q16739,O15269,Q92643,Q99805,P27544,Q13510 | Processes and pathways | GO Biological process | msigdb_gobp | 288,356,486,186,453,76,495,397,119,370,342,26,347,318 | 370,2233,495,887,397,288,1756,1352,347,1484,2190,453,318,119,571,356,342,2166,76,2302,26,186,959,486,2277 | 1.1095074471795692,-0.5261652660770593,0.7977754540117483,0.22346954691003423,1.0465360280824727,1.3937211509001355,-0.2861796454358755,-0.09708761132484221,1.2025574586113623,-0.16378257437491706,-0.49730329369665177,0.9182475647792882,1.273799811880788,2.224642100818324,0.6516446748258692,1.1614069470810378,1.2127945785226133,-0.4829371027702765,2.4485323268593073,-0.5552019842727006,2.9382790868184965,1.8751099806041622,0.17355509404966507,0.830912855432633,-0.5406616335135016 | 3,053 |
Multivesicular body | 6 | 16 | 2.759627 | 0.005787 | Q9P0T7,P10644,P14672,Q92673,P11279,Q96PU5 | Localization | GO Cellular component | msigdb_gocc | 64,191,301,54,121,287 | 640,335,191,121,1283,301,1578,2441,54,287,849,1274,1680,64,1003,789 | 0.5363090433704797,1.2230116728735583,1.8479620607680682,2.2161719066574945,-0.05750215436707501,1.3440861679024063,-0.20424086935988572,-0.6285741297543339,2.616602358730607,1.4035922338561988,0.2728886665037662,-0.044377623849349325,-0.24503774966773847,2.553174480013193,0.14840860507849105,0.33398257941175047 | 3,053 |
Proteoglycan binding | 6 | 7 | 2.753364 | 0.005899 | P07858,O00560,Q07954,O94813,P14543,Q9Y251 | Functions | GO Molecular function | msigdb_gomf | 27,168,110,207,123,223 | 168,207,27,230,123,110,223 | 1.937928245362595,1.765685690904278,2.9233715788819468,1.6821263466818883,2.199192059706801,2.26679759515337,1.710124790825368 | 3,053 |
Glycolipid binding | 7 | 10 | 2.744504 | 0.00606 | O14773,P50897,P07602,Q92643,Q9H490,Q9UM22,Q9NZJ7 | Functions | GO Molecular function | msigdb_gomf | 108,53,21,342,186,187,351 | 108,495,21,1374,53,1086,342,186,351,187 | 2.26679759515337,0.7977754540117483,3.0195749043603826,-0.1103540999259057,2.616602358730607,0.0721946227962857,1.2127945785226133,1.8751099806041622,1.192300224783089,1.8751099806041622 | 3,053 |
Antigen processing and presentation of peptide antigen via mhc class i | 6 | 11 | 2.743159 | 0.006085 | P10321,P04439,Q9UIQ6,Q03518,Q9NZ08,Q9Y6B6 | Processes and pathways | GO Biological process | msigdb_gobp | 165,105,137,234,306,313 | 1230,325,105,165,2210,1430,1972,234,306,137,313 | -0.03128805197937675,1.2535436771356345,2.2835694069887835,1.9557428487590485,-0.511712584314456,-0.13699538899316593,-0.38355670174670764,1.6727608132509426,1.334102702134965,2.122122478433616,1.3040379142045533 | 3,053 |
Protein transporter activity | 9 | 16 | 2.740946 | 0.006126 | Q9NS69,P98164,O96008,O60830,Q07820,O14925,P08069,Q9HD20,Q99595 | Functions | GO Molecular function | msigdb_gomf | 1,196,519,10,592,173,552,182,30 | 173,10,1423,519,552,603,948,196,592,690,1295,30,182,1,900,769 | 1.9289988637379116,3.2637394965616733,-0.13699538899316593,0.7420652759647238,0.674400725375824,0.5943047502828036,0.17355509404966507,1.8297870381814723,0.6173184799051494,0.4539806748878796,-0.05750215436707501,2.863344325148585,1.9021217402473265,3.6708025762594803,0.22346954691003423,0.358212818135691 | 3,053 |
Nucleotide transmembrane transporter activity | 9 | 12 | 2.738736 | 0.006168 | P12235,Q8TB61,P12236,P05141,Q9HC21,Q6NUK1,O00400,Q9H2D1,Q9BSK2 | Functions | GO Molecular function | msigdb_gomf | 100,68,103,395,299,332,508,92,95 | 508,538,395,100,103,1207,332,68,713,95,92,299 | 0.7755641462351951,0.6970555073651654,1.0570844850930035,2.308631386581677,2.291936121589696,-0.018233230344920522,1.2332088294189667,2.513161047727077,0.43020921375824495,2.3418704683845455,2.350148936285125,1.3540507039260963 | 3,053 |
Organophosphate ester transmembrane transporter activity | 9 | 12 | 2.738736 | 0.006168 | P12235,Q8TB61,P12236,P05141,Q9HC21,Q6NUK1,O00400,Q9H2D1,Q9BSK2 | Functions | GO Molecular function | msigdb_gomf | 100,68,103,395,299,332,508,92,95 | 508,538,395,100,103,1207,332,68,713,95,92,299 | 0.7755641462351951,0.6970555073651654,1.0570844850930035,2.308631386581677,2.291936121589696,-0.018233230344920522,1.2332088294189667,2.513161047727077,0.43020921375824495,2.3418704683845455,2.350148936285125,1.3540507039260963 | 3,053 |
Glycosaminoglycan degradation | 6 | 7 | 2.737828 | 0.006185 | P54802,P16278,P06865,P07686,P15586,Q9Y251 | Processes and pathways | KEGG Pathways | msigdb_kegg | 160,73,72,208,184,223 | 72,208,241,184,73,160,223 | 2.4728566349196144,1.765685690904278,1.6539802803309698,1.8841289535850934,2.4728566349196144,1.9823551672513169,1.710124790825368 | 3,053 |
Glycosaminoglycan degradation | 6 | 7 | 2.737828 | 0.006185 | P54802,P16278,P06865,P07686,P15586,Q9Y251 | Processes and pathways | WikiPathways | msigdb_wp | 160,73,72,208,184,223 | 72,208,241,184,73,160,223 | 2.4728566349196144,1.765685690904278,1.6539802803309698,1.8841289535850934,2.4728566349196144,1.9823551672513169,1.710124790825368 | 3,053 |
Ph reduction | 10 | 13 | 2.73701 | 0.0062 | Q9P0T7,O75787,Q9Y487,O75503,Q93050,Q8N511,P51790,Q14964,P50897,P51149 | Processes and pathways | GO Biological process | msigdb_gobp | 64,320,360,104,171,270,239,465,53,502 | 104,320,1096,53,502,239,604,465,270,171,64,1873,360 | 2.2835694069887835,1.2636815408562456,0.059377376010689153,2.616602358730607,0.7866818484921456,1.6633788128540579,0.5943047502828036,0.8965525637862654,1.5109728694831275,1.937928245362595,2.553174480013193,-0.32767317867730517,1.1510683617802193 | 3,053 |
Import across plasma membrane | 12 | 19 | 2.736518 | 0.006209 | P54709,P98164,P55011,P08195,P05023,P05556,O75915,P30825,P11166,Q92581,Q15043,P31751 | Processes and pathways | GO Biological process | msigdb_gobp | 480,196,390,328,394,524,523,79,243,214,407,254 | 523,394,524,328,243,79,1568,254,1128,1207,480,390,196,407,613,2413,214,763,2944 | 0.7308499991523034,1.0570844850930035,0.7308499991523034,1.2433861353171847,1.6445651501196628,2.432256446318069,-0.20424086935988572,1.5877220944504011,0.03364265519892447,-0.018233230344920522,0.8419112349230434,1.0676115247162676,1.8297870381814723,1.0359660555856258,0.5827586084337831,-0.613809285254711,1.7472293962722831,0.358212818135691,-1.2605731068481651 | 3,053 |
Phagocytic vesicle | 22 | 39 | 2.723784 | 0.006454 | P20339,P08670,P51151,P10321,Q93050,P42345,Q9UNK0,Q9BZG1,P06756,P01889,Q06481,Q04656,Q14964,P61421,P51809,Q9Y487,P04439,Q03518,P51790,Q86Y82,P11279,P51149 | Localization | GO Cellular component | msigdb_gocc | 514,666,542,165,171,554,319,579,195,325,74,203,465,604,353,360,105,234,239,246,121,502 | 1744,1325,680,1232,2797,790,325,105,195,666,165,121,514,1430,1972,1690,554,966,1758,502,542,239,353,1817,795,1541,604,968,234,203,74,465,2483,1670,246,171,579,319,360 | -0.2861796454358755,-0.08385693476833972,0.4658244563610143,-0.03128805197937675,-0.965598565884847,0.3218233565713564,1.2535436771356345,2.2835694069887835,1.8297870381814723,0.4894288560742516,1.9557428487590485,2.2161719066574945,0.7644222293835908,-0.13699538899316593,-0.38355670174670764,-0.2587130568814146,0.674400725375824,0.16099777070340407,-0.2861796454358755,0.7866818484921456,0.6970555073651654,1.6633788128540579,1.1717250589049941,-0.31380251320317754,0.3218233565713564,-0.19071746259586272,0.5943047502828036,0.16099777070340407,1.6727608132509426,1.7840786381977862,2.4566523252294235,0.8965525637862654,-0.6582416514877483,-0.24503774966773847,1.635133356253012,1.937928245362595,0.6402283550178628,1.273799811880788,1.1510683617802193 | 3,053 |
Dementia | 24 | 60 | 2.723163 | 0.006466 | P61916,Q13501,O96008,O00592,Q9Y287,P07602,P05067,P04062,O15118,Q92673,P03886,Q13510,P03915,P06865,P00403,Q14108,P17900,P27544,Q9NZJ7,P35637,Q9Y487,O76024,O60313,P36543 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 261,4,519,146,20,21,29,288,164,54,316,318,439,72,463,213,88,347,351,484,360,372,371,381 | 622,146,164,1328,1595,371,1656,372,519,463,316,439,288,2706,584,29,72,21,1565,2953,88,1723,944,888,1971,347,2263,1724,484,381,2107,1409,1129,2265,1099,1487,261,2189,2435,970,4,318,213,1359,1894,1549,2831,1076,54,659,2165,1299,2994,537,351,766,2336,1003,20,360 | 0.5595870981994009,2.070130363883016,1.9557428487590485,-0.08385693476833972,-0.21780189519795196,1.1095074471795692,-0.24503774966773847,1.1095074471795692,0.7420652759647238,0.8965525637862654,1.2838985750362097,0.9398515677513489,1.3937211509001355,-0.8557335336316402,0.6287863334786191,2.8859295440854202,2.4728566349196144,3.0195749043603826,-0.20424086935988572,-1.3116133841257678,2.3749098883187894,-0.27242694039497706,0.17355509404966507,0.22346954691003423,-0.38355670174670764,1.2025574586113623,-0.5406616335135016,-0.27242694039497706,0.830912855432633,1.088601740735695,-0.45433286929698796,-0.12365661898489545,0.03364265519892447,-0.5406616335135016,0.059377376010689153,-0.16378257437491706,1.5494862574126163,-0.49730329369665177,-0.6285741297543339,0.16099777070340407,3.430024135370345,1.273799811880788,1.7472293962722831,-0.09708761132484221,-0.34158367124160455,-0.19071746259586272,-1.0134824950248342,0.0849787193065716,2.616602358730607,0.512923337475363,-0.4829371027702765,-0.05750215436707501,-1.5757009117269876,0.7083452377706503,1.192300224783089,0.358212818135691,-0.5697866191684537,0.14840860507849105,3.026907865726523,1.1510683617802193 | 3,053 |
Vesicle membrane | 103 | 265 | 2.72247 | 0.00648 | O43731,O43493,O60499,Q8IV08,Q9Y287,P07602,Q99805,Q15012,P24390,P02786,Q14849,Q9BXS4,Q92673,Q9NQX7,P19021,Q9P0T7,P16870,Q06481,Q99523,Q7L0J3,P10253,O00462,P42892,P48960,P04439,Q9NV96,P11717,Q07954,Q5KU26,P11279,O00461,O95772,Q8TCT8,Q9HC07,Q9UIQ6,Q08722,P04114,O15127,Q13277,P30519,O15118,P10321,P61020,Q93050,O15400,P01130,P06756,P98164,Q04656,Q92542,Q15904,Q14108,Q92581,Q13190,P35613,O15260,Q03518,P51790,P15529,Q4KMQ2,Q86Y82,P11233,Q8N4V1,Q8N511,Q08431,Q8IUH4,Q96J02,Q9NR31,P14672,Q07065,P0DP25,Q9Y6B6,P20645,Q9UNK0,O75787,P01889,Q9Y3B3,P00533,Q96JJ7,O00264,Q9NZJ7,P51809,Q9H223,Q8WTV0,Q9Y487,O43760,O76024,Q15363,O14828,Q9H4M9,Q6IAA8,P55011,Q969Q5,P62820,Q15043,P51148,Q92572,Q14254,Q969E2,P20020,Q9H9H4,Q7Z6M1,Q14964 | Localization | GO Cellular component | msigdb_gocc | 0,3,8,14,20,21,26,35,37,36,49,50,54,59,63,64,70,74,77,80,93,97,101,102,105,106,109,110,122,121,120,124,125,128,137,140,144,147,154,162,164,165,166,171,169,188,195,196,203,206,209,213,214,225,229,227,234,239,236,244,246,253,267,270,278,279,281,284,301,309,311,313,312,319,320,325,330,335,344,340,351,353,357,359,360,358,372,374,369,377,386,390,399,398,407,406,420,432,444,440,450,455,465 | 914,1744,1325,1229,340,1938,622,120,97,1716,1476,369,1326,164,582,147,227,169,916,3,640,0,1533,358,1281,746,1094,1232,8,2617,2869,942,1879,1597,540,1782,1656,943,2100,790,1750,320,372,2369,1598,1450,2590,124,1451,335,188,325,36,2985,144,105,524,195,2707,21,1374,1752,1059,854,1688,311,93,165,1922,253,121,109,301,236,3031,1305,70,2788,63,440,1722,514,312,2632,37,1430,1972,162,2574,2649,2407,793,229,1693,2046,555,1409,101,1454,1600,102,697,603,966,406,502,542,1149,239,353,2864,2266,946,2455,390,166,795,1541,604,1457,1571,1662,398,1287,1208,1761,1635,196,2213,2976,968,234,203,74,309,110,2318,278,3049,140,1087,728,1950,225,154,1101,909,2355,1382,2497,213,432,1154,49,465,35,656,407,1191,776,1011,374,1605,1360,209,244,122,1825,529,2986,386,80,1491,455,246,922,657,279,14,267,270,1861,576,125,359,2441,206,420,214,54,860,171,444,399,760,636,2330,281,344,527,1299,871,77,26,849,2058,2088,3051,1472,50,2227,579,731,357,1935,377,450,128,726,1274,671,468,59,284,2229,106,3032,851,351,1680,2277,64,1714,1318,814,1966,1164,1198,2095,2572,1165,137,1302,1052,981,1621,2036,2128,1529,1419,319,1003,20,2662,1368,1531,330,789,360,1564,1324,736,313,2231,1251 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| 3,053 |
Clathrin coated vesicle membrane | 9 | 29 | 2.717859 | 0.006571 | O43493,P98164,P02786,P00533,P11717,P04114,Q14108,P20645,P01130 | Localization | GO Cellular component | msigdb_gocc | 3,196,36,335,109,144,213,312,188 | 1229,1938,3,1533,2369,1451,335,188,36,144,1059,854,1922,109,514,312,353,946,1761,196,2213,213,1154,776,1861,636,851,1302,2036 | -0.03128805197937675,-0.3695251711327288,3.585003342735257,-0.19071746259586272,-0.5990899607250865,-0.15037063254699395,1.2230116728735583,1.866075878935031,2.779747026833827,2.0788303063459717,0.09772985746096338,0.26057972136771734,-0.35553424861853866,2.26679759515337,0.7644222293835908,1.3040379142045533,1.1717250589049941,0.17355509404966507,-0.2861796454358755,1.8297870381814723,-0.511712584314456,1.7472293962722831,0.020724788531935035,0.34611234668124813,-0.32767317867730517,0.5479614575971996,0.2728886665037662,-0.05750215436707501,-0.41174265253282316 | 3,053 |
Golgi associated vesicle membrane | 7 | 22 | 2.715228 | 0.006623 | O43731,P24390,Q9Y3B3,Q8N511,Q9Y287,Q8IUH4,Q8TCT8 | Localization | GO Cellular component | msigdb_gocc | 0,37,330,270,20,279,125 | 1716,0,1533,1451,1059,854,37,793,1600,2864,2266,1571,2213,374,279,270,125,726,1198,20,330,736 | -0.27242694039497706,3.7488958239943146,-0.19071746259586272,-0.15037063254699395,0.09772985746096338,0.26057972136771734,2.779747026833827,0.3218233565713564,-0.21780189519795196,-1.0618618334058418,-0.5406616335135016,-0.20424086935988572,-0.511712584314456,1.1095074471795692,1.4526723602880829,1.5109728694831275,2.1906823149730266,0.40632489423308854,-0.005212952459059928,3.026907865726523,1.2433861353171847,0.3943400351131716 | 3,053 |
Intra golgi and retrograde golgi to er traffic | 33 | 89 | 2.712439 | 0.006679 | O43731,O43493,O60499,Q9P2W9,P62820,P54920,Q9NP72,P51151,P24390,Q9H0U4,Q10472,P20645,Q9UID3,P33908,Q8TBA6,Q9H0H5,P04350,Q15042,Q7Z6M1,Q9Y3B3,Q16706,Q10471,Q14964,P49755,O95249,Q13190,O15260,Q6NUQ1,P11717,Q15363,Q13561,O00461,O75935 | Processes and pathways | Reactome Pathways | msigdb_reactome | 0,3,8,136,398,663,671,542,37,560,178,312,573,315,577,324,584,326,455,330,593,331,465,603,224,225,227,366,109,374,504,120,499 | 1993,120,1716,227,916,2510,2742,3,0,1094,8,2869,790,499,2966,224,584,109,756,312,37,1690,315,793,667,1060,1036,2790,905,1600,603,542,1946,2577,2864,2266,663,1238,1571,398,1635,1039,2972,2434,919,1727,331,178,1950,225,1638,504,1544,1359,2498,1411,465,326,1088,374,593,2986,366,455,725,2297,1137,577,1297,1047,2658,1090,836,1494,1065,1645,324,560,937,671,2229,2741,136,1198,573,1562,330,736,2231 | -0.3976291060973344,2.2161719066574945,-0.27242694039497706,1.6914754779087535,0.19857493350037805,-0.688095106410563,-0.9025045780882558,3.585003342735257,3.7488958239943146,0.059377376010689153,3.3336104827050863,-1.0781003736110784,0.3218233565713564,0.7866818484921456,-1.363225981446116,1.7008082712982846,0.6287863334786191,2.26679759515337,0.358212818135691,1.3040379142045533,2.779747026833827,-0.2587130568814146,1.2939779145798287,0.3218233565713564,0.4894288560742516,0.09772985746096338,0.11044822745697883,-0.9497453913983102,0.21103780546535914,-0.21780189519795196,0.5943047502828036,0.6970555073651654,-0.3695251711327288,-0.7332296988017242,-1.0618618334058418,-0.5406616335135016,0.501189764703237,-0.03128805197937675,-0.20424086935988572,1.0465360280824727,-0.2314007759263953,0.11044822745697883,-1.363225981446116,-0.6285741297543339,0.19857493350037805,-0.27242694039497706,1.2332088294189667,1.9110956664873515,-0.3695251711327288,1.7008082712982846,-0.2314007759263953,0.7866818484921456,-0.19071746259586272,-0.09708761132484221,-0.6731449738170256,-0.12365661898489545,0.8965525637862654,1.2535436771356345,0.0721946227962857,1.1095074471795692,0.6173184799051494,-1.5037706134431923,1.1199288473059854,0.9182475647792882,0.40632489423308854,-0.5552019842727006,0.03364265519892447,0.6402283550178628,-0.05750215436707501,0.11044822745697883,-0.7940850336780507,0.0721946227962857,0.28516733659390786,-0.16378257437491706,0.09772985746096338,-0.2314007759263953,1.2636815408562456,0.674400725375824,0.18608075541134228,0.4894288560742516,-0.511712584314456,-0.8868625525092045,2.1393434129981372,-0.005212952459059928,0.6516446748258692,-0.19071746259586272,1.2433861353171847,0.3943400351131716,-0.511712584314456 | 3,053 |
Sphingolipid metabolism | 8 | 10 | 2.695658 | 0.007025 | P04062,O95470,P07602,O15269,Q16739,P17900,Q9NZ01,Q13510 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 288,397,21,370,119,88,378,318 | 370,2233,397,288,21,88,453,318,119,378 | 1.1095074471795692,-0.5261652660770593,1.0465360280824727,1.3937211509001355,3.0195749043603826,2.3749098883187894,0.9182475647792882,1.273799811880788,2.224642100818324,1.099065109888305 | 3,053 |
Azurophil granule lumen | 15 | 46 | 2.693441 | 0.007072 | O00584,O75629,P16278,P04066,O00560,P10619,P06280,Q92820,P53634,P07686,P08236,Q9BTY2,O00754,P15586,P17900 | Localization | GO Cellular component | msigdb_gocc | 39,7,73,43,168,141,45,175,170,208,241,84,181,184,88 | 168,39,181,1595,7,583,43,45,2707,1186,208,241,141,1881,184,73,88,2631,1507,2774,2156,2562,2073,170,1410,1487,1947,261,1039,1434,2976,2077,2190,1043,2498,1860,175,800,2225,1611,3008,84,2275,1050,2741,2307 | 1.937928245362595,2.72589277449197,1.9021217402473265,-0.21780189519795196,3.3544069953792017,0.6287863334786191,2.702652806647846,2.6715150735890525,-0.8557335336316402,-0.005212952459059928,1.765685690904278,1.6539802803309698,2.096188534692145,-0.34158367124160455,1.8841289535850934,2.4728566349196144,2.3749098883187894,-0.7787977391346896,-0.17723144136555438,-0.9339456025039627,-0.4829371027702765,-0.7181371319149215,-0.4400942588347924,1.937928245362595,-0.12365661898489545,-0.16378257437491706,-0.3695251711327288,1.5494862574126163,0.11044822745697883,-0.13699538899316593,-1.3979595289673528,-0.4400942588347924,-0.49730329369665177,0.11044822745697883,-0.6731449738170256,-0.32767317867730517,1.9289988637379116,0.3218233565713564,-0.511712584314456,-0.21780189519795196,-1.7418453203119433,2.4077523196496067,-0.5406616335135016,0.11044822745697883,-0.8868625525092045,-0.5552019842727006 | 3,053 |
Growth factor binding | 11 | 18 | 2.692602 | 0.00709 | Q15375,P06756,P98164,Q9BZZ5,O00560,Q99523,Q92896,P11717,P00533,O14786,P36896 | Functions | GO Molecular function | msigdb_gomf | 34,195,196,559,168,77,111,109,335,412,28 | 168,412,1231,335,195,552,109,1599,1756,1944,28,2909,2964,196,34,111,77,559 | 1.937928245362595,1.025374468803066,-0.03128805197937675,1.2230116728735583,1.8297870381814723,0.674400725375824,2.26679759515337,-0.21780189519795196,-0.2861796454358755,-0.3695251711327288,2.9159030325409656,-1.1601538119786206,-1.3459573008332442,1.8297870381814723,2.810290185930751,2.26679759515337,2.4485323268593073,0.674400725375824 | 3,053 |
Inner mitochondrial membrane organization | 11 | 18 | 2.691899 | 0.007105 | Q16891,Q9H3K2,Q9BUR5,Q9P0J0,Q9Y512,Q13505,Q6UXV4,O60313,Q9NVH1,O95202,Q5XKP0 | Processes and pathways | GO Biological process | msigdb_gobp | 416,226,268,400,531,23,534,371,448,249,250 | 371,780,1423,249,2969,23,416,571,250,534,268,226,448,1025,400,1278,531,769 | 1.1095074471795692,0.33398257941175047,-0.13699538899316593,1.625684832355376,-1.363225981446116,3.004880449945332,1.01476116822825,0.6516446748258692,1.625684832355376,0.7083452377706503,1.5206274845608097,1.7008082712982846,0.9398515677513489,0.1231340177911712,1.0465360280824727,-0.044377623849349325,0.7196100272359108,0.358212818135691 | 3,053 |
Alcohol binding | 6 | 14 | 2.687976 | 0.007189 | O15118,P45880,Q14849,Q14108,P21796,O95772 | Functions | GO Molecular function | msigdb_gomf | 164,135,49,213,151,124 | 469,164,887,1185,124,1752,151,2429,553,135,261,213,49,1247 | 0.8747656995030354,1.9557428487590485,0.22346954691003423,-0.005212952459059928,2.1906823149730266,-0.2861796454358755,2.0439466216934568,-0.6285741297543339,0.674400725375824,2.1393434129981372,1.5494862574126163,1.7472293962722831,2.6480472532459483,-0.03128805197937675 | 3,053 |
Six-bladed beta-propeller, TolB-like [IPR011042] | 7 | 12 | 2.686817 | 0.007214 | P98164,P98155,Q07954,Q92673,P14543,P01130,P19021 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 196,40,110,54,123,188,63 | 188,2181,123,63,40,196,110,488,1829,54,297,551 | 1.866075878935031,-0.49730329369665177,2.199192059706801,2.5690994296216365,2.7181568448827473,1.8297870381814723,2.26679759515337,0.8198908418301337,-0.31380251320317754,2.616602358730607,1.373923307859532,0.685740711671661 | 3,053 |
Copii coated er to golgi transport vesicle | 11 | 31 | 2.676981 | 0.007429 | Q13190,P10321,P01889,P04439,Q9Y3B3,P53634,O95070,Q9Y6B6,Q9Y282,Q9NR31,P05067 | Localization | GO Cellular component | msigdb_gocc | 225,165,325,105,330,170,303,313,25,284,29 | 1326,1879,943,790,1598,303,1450,2590,325,105,29,165,697,603,170,2455,625,225,374,1605,1578,883,712,1065,284,2572,25,1017,330,313,1251 | -0.08385693476833972,-0.34158367124160455,0.17355509404966507,0.3218233565713564,-0.21780189519795196,1.334102702134965,-0.15037063254699395,-0.7483704240161151,1.2535436771356345,2.2835694069887835,2.8859295440854202,1.9557428487590485,0.44210897675379346,0.5943047502828036,1.937928245362595,-0.6433848115667744,0.5595870981994009,1.7008082712982846,1.1095074471795692,-0.21780189519795196,-0.20424086935988572,0.23587033191152165,0.43020921375824495,0.09772985746096338,1.423279111691743,-0.7181371319149215,2.953147342760977,0.13578741527968066,1.2433861353171847,1.3040379142045533,-0.03128805197937675 | 3,053 |
Specific granule membrane | 7 | 14 | 2.675142 | 0.00747 | P30519,P06756,Q9NV96,Q08722,Q4KMQ2,Q07065,O00264 | Localization | GO Cellular component | msigdb_gocc | 162,195,106,140,244,309,340 | 1325,340,582,1597,195,162,309,140,244,1825,386,2227,106,1368 | -0.08385693476833972,1.2127945785226133,0.6287863334786191,-0.21780189519795196,1.8297870381814723,1.9734989342155895,1.31407865704397,2.1048469198732267,1.6445651501196628,-0.31380251320317754,1.0781172443576843,-0.511712584314456,2.2835694069887835,-0.09708761132484221 | 3,053 |
transporter | 18 | 58 | 3.708272 | 0.000209 | P39210,Q99805,Q9Y619,Q15012,P37198,O15397,Q00169,Q92973,Q9HAV4,P52948,Q567V2,Q99595,Q7Z3B4,Q9H2D1,O60830,O43772,Q9HD45,P54105 | Functions | Panther Protein class | panther_protein_class | 0,134,104,71,324,166,325,309,208,235,148,51,217,119,24,211,93,318 | 899,2639,2312,1304,1509,166,654,1744,211,790,24,901,975,771,324,0,334,1484,392,2518,1093,235,1750,1953,318,1156,2520,2105,325,955,2397,71,628,148,2931,217,1053,645,1689,859,1175,309,1849,2201,631,51,134,863,2937,865,119,208,93,1999,1506,1002,1827,104 | 0.3563379335731602,-0.8585443854221945,-0.5719634057535422,0.04733436242856619,-0.08749607248094354,1.5457402004209786,0.5725751879550428,-0.22385997559133067,1.3846557563241517,0.443262882592413,3.2734630387792905,0.3563379335731602,0.2907569811734416,0.4649035470490806,1.077809379742811,6.790697148136532,1.0571196890420318,-0.06491969310546976,0.9532161662596518,-0.7142996591987354,0.20278640880196533,1.3034573165650833,-0.22385997559133067,-0.3387194179434577,1.0984691394737887,0.15856954701810255,-0.7142996591987354,-0.4314392761759522,1.077809379742811,0.31265467698410715,-0.6192028971632252,2.2122941644519587,0.6153999674831028,1.6654410505278274,-1.4312098217663123,1.3846557563241517,0.24684817531299486,0.5940047747374697,-0.17823065580578884,0.3998733474246863,0.15856954701810255,1.1190991391688916,-0.2696675832309689,-0.47808490468523474,0.6153999674831028,2.5167589592971633,1.7447281172585196,0.3998733474246863,-1.456891576196313,0.3998733474246863,1.8236140086064396,1.4048861540431081,1.9802137107360143,-0.36182891654219795,-0.06491969310546976,0.2907569811734416,-0.24674132056841452,1.9412079120317214 | 3,053 |
Transporter activity | 42 | 175 | 3.305012 | 0.00095 | P39210,Q00535,P04920,Q9NS69,Q8IXU6,P38435,Q8IUH4,P21796,Q9NV96,O60830,Q8NEW0,P45880,P51991,Q8WTV0,Q70HW3,Q9Y487,Q99595,Q8TB61,O75438,P03886,Q9BSK2,Q9C0H2,Q9Y277,Q93050,Q14849,O15173,Q00169,Q7L0J3,Q9UBX3,P41440,Q7KZN9,O43772,P08183,O96008,Q96ES6,Q9Y619,Q9HC21,O75306,O43676,O75964,P52948,Q9H2D1 | Functions | GO Molecular function | msigdb_gomf | 0,379,378,3,133,262,12,20,282,24,157,32,288,34,35,164,51,178,54,177,56,320,68,197,70,69,325,340,81,334,89,211,92,369,96,104,103,228,111,112,235,119 | 1775,2684,715,1742,1778,513,2559,69,111,1744,211,1114,24,1307,2126,228,54,1145,2890,1038,112,1746,1711,873,2860,1584,1220,1830,369,578,177,487,1311,2009,378,2010,1712,1479,1415,2840,638,2482,92,1586,599,2358,2277,2383,488,719,1747,1553,656,3028,2324,1833,1419,2421,2513,20,979,1192,2841,796,2985,622,877,1372,2423,262,1115,0,334,32,2953,1484,1952,2517,2135,1792,879,288,235,1750,1953,1914,2066,2489,2427,2105,2854,2886,325,1322,379,2833,1161,534,1162,800,2672,802,1987,1524,70,2432,957,663,2494,2618,1564,664,2931,2969,1229,1988,539,35,89,340,12,133,2932,1202,1173,1534,157,646,178,34,2700,1811,197,96,1690,1296,1573,1297,631,51,481,863,1691,56,1853,1693,1895,1540,320,2269,1210,119,525,1242,1856,1447,103,399,3,282,2122,817,81,635,818,512,1699,2681,1901,68,164,2908,104,841,2376 | -0.24674132056841452,-0.90706803754792,0.5080778484189623,-0.22385997559133067,-0.24674132056841452,0.7430608810149629,-0.7621641673616228,2.2122941644519587,1.882519935756883,-0.22385997559133067,1.3846557563241517,0.1806975002667812,3.2734630387792905,0.04733436242856619,-0.45473795795566646,1.3237987550526746,2.4600887755522476,0.15856954701810255,-1.303841118998535,0.24684817531299486,1.882519935756883,-0.22385997559133067,-0.20102320141396507,0.3781239970118069,-1.2031510377233365,-0.13277690412101875,0.11419540272429664,-0.2696675832309689,0.9948692957811976,0.6580880397299336,1.5056302422299026,0.7853489674913086,0.04733436242856619,-0.38498514034941356,0.9740581370180955,-0.38498514034941356,-0.20102320141396507,-0.06491969310546976,-0.019893426729216315,-1.1531926286514946,0.5940047747374697,-0.6904471283524107,2.0191249668757036,-0.13277690412101875,0.6367609840083165,-0.5955577777283037,-0.5484193521639549,-0.6192028971632252,0.7853489674913086,0.5080778484189623,-0.22385997559133067,-0.11011503607208795,0.5725751879550428,-2.6679032221381274,-0.5719634057535422,-0.2696675832309689,-0.019893426729216315,-0.6428991995691181,-0.7142996591987354,3.381602740630259,0.2907569811734416,0.13640227399311802,-1.1531926286514946,0.443262882592413,-1.9593339662988416,0.6153999674831028,0.3781239970118069,0.0025570802874198603,-0.6428991995691181,1.2218086022023797,0.1806975002667812,6.790697148136532,1.0571196890420318,2.8158980590558365,-1.534366639104802,-0.06491969310546976,-0.3387194179434577,-0.7142996591987354,-0.45473795795566646,-0.24674132056841452,0.3781239970118069,1.1602705337166455,1.3034573165650833,-0.22385997559133067,-0.3387194179434577,-0.3156562729795899,-0.4081884661759546,-0.6904471283524107,-0.6428991995691181,-0.4314392761759522,-1.1781401567013674,-1.278570283055428,1.077809379742811,0.04733436242856619,0.9740581370180955,-1.1283078220968537,0.15856954701810255,0.7218675610316574,0.15856954701810255,0.443262882592413,-0.8827779909790987,0.443262882592413,-0.36182891654219795,-0.08749607248094354,2.2122941644519587,-0.6428991995691181,0.31265467698410715,0.5725751879550428,-0.6904471283524107,-0.8102444399713625,-0.11011503607208795,0.5725751879550428,-1.4312098217663123,-1.6649735266333288,0.11419540272429664,-0.36182891654219795,0.7218675610316574,2.7415926503073877,2.0579425824732125,1.0571196890420318,3.8432367226477653,1.7447281172585196,-1.4312098217663123,0.13640227399311802,0.15856954701810255,-0.08749607248094354,1.585744595846163,0.5940047747374697,1.5056302422299026,2.760198415947888,-0.90706803754792,-0.24674132056841452,1.4452649342552104,1.9607226861740548,-0.17823065580578884,0.06966173419709126,-0.11011503607208795,0.06966173419709126,0.6153999674831028,2.5167589592971633,0.8064441353972578,0.3998733474246863,-0.17823065580578884,2.422203483979085,-0.2696675832309689,-0.17823065580578884,-0.29263911521091057,-0.08749607248094354,1.0984691394737887,-0.524925194185422,0.13640227399311802,1.8236140086064396,0.7430608810149629,0.11419540272429664,-0.2696675832309689,-0.019893426729216315,1.9412079120317214,0.9532161662596518,5.592463933325356,1.1808122620382033,-0.4314392761759522,0.443262882592413,2.154582729798314,0.6153999674831028,0.443262882592413,0.7642212825740413,-0.17823065580578884,-0.8827779909790987,-0.29263911521091057,2.2314864977762854,1.5657555247047086,-1.3291786390974751,1.9412079120317214,0.42158622887203256,-0.5955577777283037 | 3,053 |
Tetrapyrrole binding | 6 | 16 | 3.077017 | 0.002091 | Q16850,O43169,O15173,P09601,P30519,Q7KZN9 | Functions | GO Molecular function | msigdb_gomf | 153,7,69,11,17,89 | 617,69,7,599,11,2514,17,175,153,89,888,588,589,575,785,1110 | 0.6153999674831028,2.2122941644519587,4.311451611231286,0.6367609840083165,3.9307710524391237,-0.7142996591987354,3.542657367414011,1.5256984857604572,1.6057075498374067,2.0579425824732125,0.3781239970118069,0.6580880397299336,0.6580880397299336,0.6793813477027839,0.4649035470490806,0.20278640880196533 | 3,053 |
Response to oxidative stress | 16 | 93 | 3.062533 | 0.002195 | P39210,Q969S3,Q15392,O75306,Q8TED1,O43169,Q14145,P09601,O15111,O95831,P00374,P30519,P00390,Q13546,O75874,Q9UL15 | Processes and pathways | GO Biological process | msigdb_gobp | 0,291,4,228,230,7,42,11,165,268,16,17,85,276,90,253 | 1703,165,7,1829,1623,228,2782,1368,528,90,2414,1711,681,268,16,85,2008,487,1311,2739,2416,2275,3023,2784,1371,2011,1271,11,2542,2359,502,2624,656,2130,285,1191,1039,846,1630,1715,1593,1557,981,1835,2588,2057,2282,17,1950,2516,2547,1878,3030,2132,0,1070,1150,2726,1427,1429,1487,1162,2069,2672,2334,883,276,42,436,1168,4,584,1229,686,2031,1535,230,1328,291,1537,1358,1206,1262,1538,2878,1029,893,896,2601,2407,616,2535,253 | -0.20102320141396507,1.5457402004209786,4.311451611231286,-0.2696675832309689,-0.1554820011028002,1.3237987550526746,-1.0540235788334475,0.0025570802874198603,0.7218675610316574,2.0385454239533916,-0.6428991995691181,-0.20102320141396507,0.5511109868815428,1.2013248973084056,3.542657367414011,2.115995366359213,-0.38498514034941356,0.7853489674913086,0.04733436242856619,-0.9802821143207153,-0.6428991995691181,-0.5484193521639549,-2.4640563858494313,-1.0540235788334475,0.0025570802874198603,-0.38498514034941356,0.06966173419709126,3.9307710524391237,-0.7382051822514453,-0.5955577777283037,0.7642212825740413,-0.8343667044836434,0.5725751879550428,-0.45473795795566646,1.1602705337166455,0.13640227399311802,0.24684817531299486,0.3998733474246863,-0.1554820011028002,-0.20102320141396507,-0.13277690412101875,-0.11011503607208795,0.2907569811734416,-0.2696675832309689,-0.7861770917100085,-0.4081884661759546,-0.5484193521639549,3.542657367414011,-0.3387194179434577,-0.7142996591987354,-0.7382051822514453,-0.29263911521091057,-2.756494966537112,-0.45473795795566646,6.790697148136532,0.22483654434088843,0.15856954701810255,-0.9558195614505496,-0.019893426729216315,-0.019893426729216315,-0.06491969310546976,0.15856954701810255,-0.4081884661759546,-0.8827779909790987,-0.5719634057535422,0.3781239970118069,1.1808122620382033,2.6482659504229598,0.8695365017538665,0.15856954701810255,5.036022265834179,0.6580880397299336,0.11419540272429664,0.5511109868815428,-0.38498514034941356,-0.08749607248094354,1.3237987550526746,0.04733436242856619,1.1602705337166455,-0.08749607248094354,0.02496624326774895,0.13640227399311802,0.09194865127890278,-0.08749607248094354,-1.2533654408572235,0.26882156691646053,0.3781239970118069,0.3781239970118069,-0.7861770917100085,-0.6192028971632252,0.6367609840083165,-0.7142996591987354,1.262689863668224 | 3,053 |
Mitochondrial substrate/solute carrier [IPR018108] | 7 | 20 | 2.93346 | 0.003352 | Q70HW3,Q9Y619,Q9HC21,Q9UBX3,Q9H2D1,Q9BSK2,O43772 | Sequence | InterPro Repeat | interpro_repeat | 35,104,103,81,119,56,211 | 211,1114,2890,1712,488,719,1750,1322,1161,1229,35,56,119,1242,103,354,81,1699,104,971 | 1.3846557563241517,0.1806975002667812,-1.303841118998535,-0.20102320141396507,0.7853489674913086,0.5080778484189623,-0.22385997559133067,0.04733436242856619,0.15856954701810255,0.11419540272429664,2.7415926503073877,2.422203483979085,1.8236140086064396,0.11419540272429664,1.9412079120317214,1.036399894714161,2.154582729798314,-0.17823065580578884,1.9412079120317214,0.31265467698410715 | 3,053 |
Mitochondrial carrier domain superfamily [IPR023395] | 7 | 20 | 2.93346 | 0.003352 | Q70HW3,Q9Y619,Q9HC21,Q9UBX3,Q9H2D1,Q9BSK2,O43772 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 35,104,103,81,119,56,211 | 211,1114,2890,1712,488,719,1750,1322,1161,1229,35,56,119,1242,103,354,81,1699,104,971 | 1.3846557563241517,0.1806975002667812,-1.303841118998535,-0.20102320141396507,0.7853489674913086,0.5080778484189623,-0.22385997559133067,0.04733436242856619,0.15856954701810255,0.11419540272429664,2.7415926503073877,2.422203483979085,1.8236140086064396,0.11419540272429664,1.9412079120317214,1.036399894714161,2.154582729798314,-0.17823065580578884,1.9412079120317214,0.31265467698410715 | 3,053 |
SLC25 family of mitochondrial transporters | 7 | 20 | 2.93346 | 0.003352 | Q70HW3,Q9Y619,Q9HC21,Q9UBX3,Q9H2D1,Q9BSK2,O43772 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 35,104,103,81,119,56,211 | 211,1114,2890,1712,488,719,1750,1322,1161,1229,35,56,119,1242,103,354,81,1699,104,971 | 1.3846557563241517,0.1806975002667812,-1.303841118998535,-0.20102320141396507,0.7853489674913086,0.5080778484189623,-0.22385997559133067,0.04733436242856619,0.15856954701810255,0.11419540272429664,2.7415926503073877,2.422203483979085,1.8236140086064396,0.11419540272429664,1.9412079120317214,1.036399894714161,2.154582729798314,-0.17823065580578884,1.9412079120317214,0.31265467698410715 | 3,053 |
SLC superfamily of solute carriers | 13 | 47 | 2.875955 | 0.004028 | Q70HW3,Q8IXU6,Q9NZJ7,Q9Y619,Q9HC21,Q7L0J3,Q9UBX3,Q8TB61,P41440,Q9H2D1,Q9BSK2,O43772,Q8NEW0 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 35,133,354,104,103,340,81,178,334,119,56,211,157 | 715,211,1114,2890,1584,378,1712,1586,2383,488,719,1553,622,334,1750,1953,1914,1322,1161,2432,2494,2931,1229,1988,35,340,133,157,178,2700,1690,1296,863,56,1895,2269,119,1242,1856,1447,103,354,81,1699,104,971,841 | 0.5080778484189623,1.3846557563241517,0.1806975002667812,-1.303841118998535,-0.13277690412101875,0.9740581370180955,-0.20102320141396507,-0.13277690412101875,-0.6192028971632252,0.7853489674913086,0.5080778484189623,-0.11011503607208795,0.6153999674831028,1.0571196890420318,-0.22385997559133067,-0.3387194179434577,-0.3156562729795899,0.04733436242856619,0.15856954701810255,-0.6428991995691181,-0.6904471283524107,-1.4312098217663123,0.11419540272429664,-0.36182891654219795,2.7415926503073877,1.0571196890420318,1.7447281172585196,1.585744595846163,1.5056302422299026,-0.90706803754792,-0.17823065580578884,0.06966173419709126,0.3998733474246863,2.422203483979085,-0.29263911521091057,-0.524925194185422,1.8236140086064396,0.11419540272429664,-0.2696675832309689,-0.019893426729216315,1.9412079120317214,1.036399894714161,2.154582729798314,-0.17823065580578884,1.9412079120317214,0.31265467698410715,0.42158622887203256 | 3,053 |
Outer membrane | 23 | 80 | 2.840728 | 0.004501 | Q92667,Q9NS69,Q96TC7,O43169,P09601,P21796,P52789,O60313,P45880,Q9NVH1,O00429,Q9NVH0,Q9Y277,Q8N0X7,Q8IWA4,Q8WY22,Q9UBF8,Q9NZJ7,Q8N4H5,Q9NZ45,Q7Z434,O96008,Q6NUM9 | Localization | GO Cellular component | msigdb_gocc | 128,3,398,7,11,20,156,402,32,432,315,331,68,77,341,207,83,354,237,240,245,369,260 | 617,315,2899,7,402,1270,1872,2688,1746,1585,369,2562,2883,1552,11,2710,20,2097,2871,600,2186,32,930,156,2745,698,2330,800,2672,1119,2716,957,2336,1351,1386,1465,538,260,1126,245,1052,341,1022,2144,77,237,2674,1202,2301,1732,207,128,1645,398,1851,2779,1029,1107,2597,1853,2764,2811,2307,813,454,3,331,432,2449,710,836,240,354,83,837,1998,68,2968,926,971 | 0.6153999674831028,1.0984691394737887,-1.3291786390974751,4.311451611231286,0.9323432018484419,0.06966173419709126,-0.29263911521091057,-0.90706803754792,-0.22385997559133067,-0.13277690412101875,0.9948692957811976,-0.7621641673616228,-1.278570283055428,-0.11011503607208795,3.9307710524391237,-0.9314150499140011,3.381602740630259,-0.4314392761759522,-1.2282259143903864,0.6367609840083165,-0.47808490468523474,2.8158980590558365,0.3345149101794884,1.585744595846163,-0.9802821143207153,0.5296119487856337,-0.5719634057535422,0.443262882592413,-0.8827779909790987,0.1806975002667812,-0.9314150499140011,0.31265467698410715,-0.5719634057535422,0.02496624326774895,0.0025570802874198603,-0.04238558185808609,0.7218675610316574,1.2422635378120828,0.1806975002667812,1.2830877377617704,0.24684817531299486,1.0571196890420318,0.26882156691646053,-0.45473795795566646,2.1738423843041677,1.3034573165650833,-0.8827779909790987,0.13640227399311802,-0.5484193521639549,-0.20102320141396507,1.4048861540431081,1.764486885826947,-0.1554820011028002,0.9532161662596518,-0.2696675832309689,-1.0293835579205086,0.26882156691646053,0.20278640880196533,-0.7861770917100085,-0.2696675832309689,-1.0048032596858985,-1.078723901896545,-0.5484193521639549,0.443262882592413,0.8485377081326498,5.592463933325356,1.077809379742811,0.8905035560094133,-0.6428991995691181,0.5296119487856337,0.42158622887203256,1.3034573165650833,1.036399894714161,2.1353004258067396,0.42158622887203256,-0.36182891654219795,2.2314864977762854,-1.6386999972988514,0.3563379335731602,0.31265467698410715 | 3,053 |
Sphingolipid biosynthetic process | 6 | 17 | 2.814937 | 0.004879 | P27544,O95470,Q99805,Q06136,Q16739,Q96G23 | Processes and pathways | GO Biological process | msigdb_gobp | 95,224,134,8,215,29 | 249,653,224,1311,1666,979,95,2069,8,2993,215,1386,29,134,836,732,1650 | 1.262689863668224,0.5725751879550428,1.3441122067215945,0.04733436242856619,-0.17823065580578884,0.2907569811734416,1.9607226861740548,-0.4081884661759546,4.242764840201137,-2.013970850691003,1.3846557563241517,0.0025570802874198603,2.9451879305659427,1.7447281172585196,0.42158622887203256,0.5080778484189623,-0.1554820011028002 | 3,053 |
Anion transmembrane transport | 13 | 43 | 2.812737 | 0.004912 | P45880,Q9UHG3,Q9Y277,Q9Y619,Q9HC21,Q9UBX3,P21796,Q9HD26,Q8TB61,P41440,Q9H2D1,Q13546,P08183 | Processes and pathways | GO Biological process | msigdb_gobp | 32,37,68,104,103,81,20,281,178,334,119,276,92 | 1114,499,2890,2414,378,1712,2357,92,1586,488,719,20,622,334,32,2135,1792,1750,1953,1914,2886,1322,1161,276,2494,664,2969,178,2700,1690,1895,119,1242,1856,103,281,81,37,1699,68,2166,104,841 | 0.1806975002667812,0.7642212825740413,-1.303841118998535,-0.6428991995691181,0.9740581370180955,-0.20102320141396507,-0.5955577777283037,2.0191249668757036,-0.13277690412101875,0.7853489674913086,0.5080778484189623,3.381602740630259,0.6153999674831028,1.0571196890420318,2.8158980590558365,-0.45473795795566646,-0.24674132056841452,-0.22385997559133067,-0.3387194179434577,-0.3156562729795899,-1.278570283055428,0.04733436242856619,0.15856954701810255,1.1808122620382033,-0.6904471283524107,0.5725751879550428,-1.6649735266333288,1.5056302422299026,-0.90706803754792,-0.17823065580578884,-0.29263911521091057,1.8236140086064396,0.11419540272429664,-0.2696675832309689,1.9412079120317214,1.1808122620382033,2.154582729798314,2.722967138304573,-0.17823065580578884,2.2314864977762854,-0.45473795795566646,1.9412079120317214,0.42158622887203256 | 3,053 |
Secondary alcohol metabolic process | 10 | 43 | 2.741572 | 0.006115 | Q14534,Q8WTV0,Q9BQE5,Q15392,P48449,Q14849,Q06520,Q16850,O75874,P48735 | Processes and pathways | GO Biological process | msigdb_gobp | 160,34,67,4,36,70,14,153,90,121 | 2559,947,90,2479,2562,2988,1311,2009,2784,502,1945,822,2666,720,294,1346,2789,36,121,2818,1598,931,2854,626,2331,2292,14,2298,160,193,70,1382,2194,4,2760,724,153,34,2575,67,1210,837,1900 | -0.7621641673616228,0.31265467698410715,2.0385454239533916,-0.6904471283524107,-0.7621641673616228,-1.986607236530285,0.04733436242856619,-0.38498514034941356,-1.0540235788334475,0.7642212825740413,-0.3387194179434577,0.42158622887203256,-0.8827779909790987,0.5080778484189623,1.1396995480631378,0.02496624326774895,-1.0540235788334475,2.722967138304573,1.803929707635828,-1.1034851164802537,-0.13277690412101875,0.3345149101794884,-1.1781401567013674,0.6153999674831028,-0.5719634057535422,-0.5484193521639549,3.666989822854212,-0.5484193521639549,1.5657555247047086,1.4452649342552104,2.2122941644519587,0.0025570802874198603,-0.47808490468523474,5.036022265834179,-1.0048032596858985,0.5080778484189623,1.6057075498374067,2.760198415947888,-0.7621641673616228,2.2506565969990633,0.13640227399311802,0.42158622887203256,-0.29263911521091057 | 3,053 |
External ophthalmoplegia | 7 | 14 | 2.681445 | 0.007331 | Q14331,Q07021,P51530,P12235,P03915,P03886,O60313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 326,105,203,488,487,177,402 | 402,1873,578,177,487,488,845,1315,2017,1485,203,105,326,1302 | 0.9323432018484419,-0.29263911521091057,0.6580880397299336,1.5056302422299026,0.7853489674913086,0.7853489674913086,0.3998733474246863,0.04733436242856619,-0.38498514034941356,-0.06491969310546976,1.4250891645523671,1.9216692731632823,1.077809379742811,0.06966173419709126 | 3,053 |
Nucleobase containing compound transmembrane transporter activity | 8 | 14 | 2.60937 | 0.009071 | P51991,Q9HC21,P12236,P12235,Q8TB61,P41440,Q9H2D1,Q9BSK2 | Functions | GO Molecular function | msigdb_gomf | 288,103,719,488,178,334,119,56 | 1775,715,1114,1712,488,719,334,288,1229,178,863,56,119,103 | -0.24674132056841452,0.5080778484189623,0.1806975002667812,-0.20102320141396507,0.7853489674913086,0.5080778484189623,1.0571196890420318,1.1602705337166455,0.11419540272429664,1.5056302422299026,0.3998733474246863,2.422203483979085,1.8236140086064396,1.9412079120317214 | 3,053 |
Mitochondrial transmembrane transport | 9 | 47 | 2.53049 | 0.01139 | Q9Y619,P23786,O43772,O75964,P21796,Q99595,Q9H2D1,O60830,Q9BSK2 | Processes and pathways | GO Biological process | msigdb_gobp | 104,130,211,112,20,51,119,24,56 | 513,654,211,24,1307,1583,2890,1038,112,1746,1584,268,369,1712,1479,2900,488,719,20,130,1192,2841,1372,2953,1750,2066,2489,1322,957,1350,1803,539,1130,1534,1535,1690,51,2343,56,119,1242,1856,2858,1699,1002,2211,104 | 0.7430608810149629,0.5725751879550428,1.3846557563241517,3.2734630387792905,0.04733436242856619,-0.13277690412101875,-1.303841118998535,0.24684817531299486,1.882519935756883,-0.22385997559133067,-0.13277690412101875,1.2013248973084056,0.9948692957811976,-0.20102320141396507,-0.06491969310546976,-1.3291786390974751,0.7853489674913086,0.5080778484189623,3.381602740630259,1.7447281172585196,0.13640227399311802,-1.1531926286514946,0.0025570802874198603,-1.534366639104802,-0.22385997559133067,-0.4081884661759546,-0.6904471283524107,0.04733436242856619,0.31265467698410715,0.02496624326774895,-0.24674132056841452,0.7218675610316574,0.1806975002667812,-0.08749607248094354,-0.08749607248094354,-0.17823065580578884,2.5167589592971633,-0.5719634057535422,2.422203483979085,1.8236140086064396,0.11419540272429664,-0.2696675832309689,-1.1781401567013674,-0.17823065580578884,0.2907569811734416,-0.47808490468523474,1.9412079120317214 | 3,053 |
Mitochondrion organization | 50 | 176 | 2.528767 | 0.011446 | P39210,Q00535,Q9NS69,O14925,Q9H3K2,O95831,P21796,Q9NVI7,Q9H061,O60830,Q5XKP0,P52789,O60313,P45880,Q5JRX3,Q9NVH1,Q96A26,Q13501,Q99595,P03886,O75438,Q5TC12,Q9BSK2,O75153,O00429,Q9Y2R0,Q10713,P14406,Q9UG56,P51530,Q8IWA4,Q9UDX5,P49815,Q6DKK2,Q99797,O95429,Q9Y4P8,P27544,Q5T9A4,O75306,P55786,Q8N4H5,Q7L592,Q9NUQ9,O43676,P12235,P03915,O96008,P11233,Q9Y4P1 | Processes and pathways | GO Biological process | msigdb_gobp | 0,379,3,513,272,268,20,546,23,24,538,156,402,32,169,432,298,47,51,177,54,308,56,57,315,201,462,323,343,203,341,84,335,88,481,220,98,95,362,228,99,237,364,113,111,488,487,369,242,124 | 597,315,527,513,716,1829,654,111,2049,402,24,57,3024,2126,228,1872,2688,54,1583,1145,598,2052,1746,1711,873,1584,1220,1873,739,220,1625,268,1830,369,2738,2966,177,487,1311,2416,2275,1712,1943,1552,2542,2940,2900,242,488,323,2544,20,95,1593,2985,2057,2282,1978,1950,2362,2827,2649,2132,2871,0,2789,1596,32,2327,335,1790,1224,1912,909,203,2591,879,156,99,2902,881,2429,1431,379,1162,2332,800,462,47,1119,989,628,2716,957,663,2336,701,1887,2618,1564,1351,1121,1803,1386,169,362,308,538,88,1126,364,2821,1925,1171,341,1022,2144,2145,1289,237,2674,1534,2301,1535,2677,298,861,1645,1330,2115,705,2878,1851,51,2779,2266,481,1264,56,1692,1107,2597,2764,1541,2237,23,272,2120,2858,813,3,1001,113,432,546,2449,710,2634,817,1934,84,343,1998,1544,1002,2948,201,713,2968,124,98,2211,926,2908,971,2376 | 0.6367609840083165,1.0984691394737887,0.7218675610316574,0.7430608810149629,0.5080778484189623,-0.2696675832309689,0.5725751879550428,1.882519935756883,-0.4081884661759546,0.9323432018484419,3.2734630387792905,2.403229007470206,-2.4929274830098986,-0.45473795795566646,1.3237987550526746,-0.29263911521091057,-0.90706803754792,2.4600887755522476,-0.13277690412101875,0.15856954701810255,0.6367609840083165,-0.4081884661759546,-0.22385997559133067,-0.20102320141396507,0.3781239970118069,-0.13277690412101875,0.11419540272429664,-0.29263911521091057,0.48650845797534237,1.364397823611464,-0.1554820011028002,1.2013248973084056,-0.2696675832309689,0.9948692957811976,-0.9802821143207153,-1.6386999972988514,1.5056302422299026,0.7853489674913086,0.04733436242856619,-0.6428991995691181,-0.5484193521639549,-0.20102320141396507,-0.3387194179434577,-0.11011503607208795,-0.7382051822514453,-1.4826444366763971,-1.3291786390974751,1.2830877377617704,0.7853489674913086,1.077809379742811,-0.7382051822514453,3.381602740630259,1.9607226861740548,-0.13277690412101875,-1.9593339662988416,-0.4081884661759546,-0.5484193521639549,-0.36182891654219795,-0.3387194179434577,-0.5955577777283037,-1.1283078220968537,-0.8585443854221945,-0.45473795795566646,-1.2282259143903864,6.790697148136532,-1.0540235788334475,-0.13277690412101875,2.8158980590558365,-0.5719634057535422,1.0571196890420318,-0.24674132056841452,0.11419540272429664,-0.3156562729795899,0.3563379335731602,1.4250891645523671,-0.7861770917100085,0.3781239970118069,1.585744595846163,1.9412079120317214,-1.3291786390974751,0.3781239970118069,-0.6428991995691181,-0.019893426729216315,0.9740581370180955,0.15856954701810255,-0.5719634057535422,0.443262882592413,0.8275069838030819,2.573242040306225,0.1806975002667812,0.2907569811734416,0.6153999674831028,-0.9314150499140011,0.31265467698410715,0.5725751879550428,-0.5719634057535422,0.5296119487856337,-0.29263911521091057,-0.8102444399713625,-0.11011503607208795,0.02496624326774895,0.1806975002667812,-0.24674132056841452,0.0025570802874198603,1.5457402004209786,1.0156498223536288,1.1190991391688916,0.7218675610316574,2.0579425824732125,0.1806975002667812,1.0156498223536288,-1.1034851164802537,-0.3156562729795899,0.15856954701810255,1.0571196890420318,0.26882156691646053,-0.45473795795566646,-0.45473795795566646,0.06966173419709126,1.3034573165650833,-0.8827779909790987,-0.08749607248094354,-0.5484193521639549,-0.08749607248094354,-0.8827779909790987,1.1396995480631378,0.3998733474246863,-0.1554820011028002,0.04733436242856619,-0.4314392761759522,0.5296119487856337,-1.2533654408572235,-0.2696675832309689,2.5167589592971633,-1.0293835579205086,-0.524925194185422,0.8064441353972578,0.09194865127890278,2.422203483979085,-0.17823065580578884,0.20278640880196533,-0.7861770917100085,-1.0048032596858985,-0.08749607248094354,-0.501480515213417,3.291529859154659,1.2013248973084056,-0.4314392761759522,-1.1781401567013674,0.443262882592413,5.592463933325356,0.2907569811734416,1.882519935756883,0.8905035560094133,0.7218675610316574,-0.6428991995691181,0.5296119487856337,-0.8343667044836434,0.443262882592413,-0.3156562729795899,2.1353004258067396,1.0571196890420318,-0.36182891654219795,-0.08749607248094354,0.2907569811734416,-1.508469190198362,1.4452649342552104,0.5296119487856337,-1.6386999972988514,1.803929707635828,1.9607226861740548,-0.47808490468523474,0.3563379335731602,-1.3291786390974751,0.31265467698410715,-0.5955577777283037 | 3,053 |
Ion transmembrane transporter activity | 32 | 101 | 2.528656 | 0.01145 | Q00535,P04920,Q9H813,Q9HD20,Q8IUH4,P21796,Q6P4A7,Q4KMQ2,Q8NEW0,Q15526,P45880,Q70HW3,Q9Y487,Q8TB61,Q9C0H2,Q9Y277,Q93050,P00403,Q9UBX3,P41440,Q7KZN9,O43772,P08574,Q96ES6,Q9Y619,Q9HC21,Q9UDW1,P12235,O75964,Q9UI12,Q9H2D1,P30825 | Functions | GO Molecular function | msigdb_gomf | 379,378,525,399,12,20,539,664,157,663,32,35,164,178,320,68,197,578,81,334,89,211,599,96,104,103,635,488,112,512,119,622 | 2684,715,1744,211,1114,2890,1038,112,1584,578,378,2010,1712,1479,1415,2840,2482,1586,599,2358,2277,2383,488,719,1747,656,1833,1419,2421,2513,20,1192,2841,622,877,1372,2423,1115,334,32,2953,2135,1792,1750,1953,1914,2066,2489,2427,2105,1322,379,1161,1162,802,1524,2432,663,2494,664,2931,2969,1229,1988,539,35,89,12,2932,1534,157,178,2700,1811,197,96,1690,1296,1573,863,1853,1895,320,2269,119,525,1242,1856,1447,103,399,2122,81,635,512,1699,2681,68,164,104,841 | -0.90706803754792,0.5080778484189623,-0.22385997559133067,1.3846557563241517,0.1806975002667812,-1.303841118998535,0.24684817531299486,1.882519935756883,-0.13277690412101875,0.6580880397299336,0.9740581370180955,-0.38498514034941356,-0.20102320141396507,-0.06491969310546976,-0.019893426729216315,-1.1531926286514946,-0.6904471283524107,-0.13277690412101875,0.6367609840083165,-0.5955577777283037,-0.5484193521639549,-0.6192028971632252,0.7853489674913086,0.5080778484189623,-0.22385997559133067,0.5725751879550428,-0.2696675832309689,-0.019893426729216315,-0.6428991995691181,-0.7142996591987354,3.381602740630259,0.13640227399311802,-1.1531926286514946,0.6153999674831028,0.3781239970118069,0.0025570802874198603,-0.6428991995691181,0.1806975002667812,1.0571196890420318,2.8158980590558365,-1.534366639104802,-0.45473795795566646,-0.24674132056841452,-0.22385997559133067,-0.3387194179434577,-0.3156562729795899,-0.4081884661759546,-0.6904471283524107,-0.6428991995691181,-0.4314392761759522,0.04733436242856619,0.9740581370180955,0.15856954701810255,0.15856954701810255,0.443262882592413,-0.08749607248094354,-0.6428991995691181,0.5725751879550428,-0.6904471283524107,0.5725751879550428,-1.4312098217663123,-1.6649735266333288,0.11419540272429664,-0.36182891654219795,0.7218675610316574,2.7415926503073877,2.0579425824732125,3.8432367226477653,-1.4312098217663123,-0.08749607248094354,1.585744595846163,1.5056302422299026,-0.90706803754792,-0.24674132056841452,1.4452649342552104,1.9607226861740548,-0.17823065580578884,0.06966173419709126,-0.11011503607208795,0.3998733474246863,-0.2696675832309689,-0.29263911521091057,1.0984691394737887,-0.524925194185422,1.8236140086064396,0.7430608810149629,0.11419540272429664,-0.2696675832309689,-0.019893426729216315,1.9412079120317214,0.9532161662596518,-0.4314392761759522,2.154582729798314,0.6153999674831028,0.7642212825740413,-0.17823065580578884,-0.8827779909790987,2.2314864977762854,1.5657555247047086,1.9412079120317214,0.42158622887203256 | 3,053 |
Metalloendopeptidase activity | 6 | 14 | 2.479122 | 0.013171 | O43847,Q9BYT8,Q5JRX3,Q10713,Q92905,O75844 | Functions | GO Molecular function | msigdb_gomf | 345,367,169,462,138,45 | 345,1583,45,1452,1786,741,742,462,169,138,2115,481,367,2211 | 1.036399894714161,-0.13277690412101875,2.5920285763758244,-0.04238558185808609,-0.24674132056841452,0.48650845797534237,0.48650845797534237,0.8275069838030819,1.5457402004209786,1.724944276613307,-0.4314392761759522,0.8064441353972578,1.0156498223536288,-0.47808490468523474 | 3,053 |
Steroid binding | 6 | 20 | 2.46907 | 0.013546 | P45880,P38435,Q14849,O15173,O95772,P21796 | Functions | GO Molecular function | msigdb_gomf | 32,262,70,69,173,20 | 617,2559,69,2479,173,1311,2010,2482,20,979,2646,294,262,32,2854,1756,70,1297,1693,1540 | 0.6153999674831028,-0.7621641673616228,2.2122941644519587,-0.6904471283524107,1.5256984857604572,0.04733436242856619,-0.38498514034941356,-0.6904471283524107,3.381602740630259,0.2907569811734416,-0.8585443854221945,1.1396995480631378,1.2218086022023797,2.8158980590558365,-1.1781401567013674,-0.22385997559133067,2.2122941644519587,0.06966173419709126,-0.17823065580578884,-0.08749607248094354 | 3,053 |
Membrane lipid biosynthetic process | 8 | 25 | 2.467335 | 0.013612 | Q8NBX0,Q9H490,Q99805,P27544,O95470,Q06136,Q16739,Q96G23 | Processes and pathways | GO Biological process | msigdb_gobp | 194,135,134,95,224,8,215,29 | 249,653,2889,2839,224,1311,1666,979,95,1595,2069,8,2993,215,1386,194,453,2678,29,2732,134,135,836,732,1650 | 1.262689863668224,0.5725751879550428,-1.303841118998535,-1.1531926286514946,1.3441122067215945,0.04733436242856619,-0.17823065580578884,0.2907569811734416,1.9607226861740548,-0.13277690412101875,-0.4081884661759546,4.242764840201137,-2.013970850691003,1.3846557563241517,0.0025570802874198603,1.4452649342552104,0.8485377081326498,-0.8827779909790987,2.9451879305659427,-0.9558195614505496,1.7447281172585196,1.7447281172585196,0.42158622887203256,0.5080778484189623,-0.1554820011028002 | 3,053 |
Intestinal malrotation | 7 | 28 | 2.464351 | 0.013726 | Q14739,Q6W2J9,Q15392,P54198,Q92766,Q9BV10,P21964 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 193,65,4,236,122,252,225 | 1217,274,1907,2453,1584,682,2360,225,932,236,1914,2886,1560,2295,2777,193,4,2075,65,1495,122,2033,941,252,1472,837,2780,867 | 0.11419540272429664,1.1808122620382033,-0.3156562729795899,-0.6666471270313368,-0.13277690412101875,0.5511109868815428,-0.5955577777283037,1.3441122067215945,0.3345149101794884,1.3034573165650833,-0.3156562729795899,-1.278570283055428,-0.11011503607208795,-0.5484193521639549,-1.0293835579205086,1.4452649342552104,5.036022265834179,-0.4081884661759546,2.2889304994100175,-0.06491969310546976,1.803929707635828,-0.38498514034941356,0.3345149101794884,1.262689863668224,-0.04238558185808609,0.42158622887203256,-1.0293835579205086,0.3998733474246863 | 3,053 |
Protein targeting | 27 | 102 | 2.45945 | 0.013915 | P61009,Q00535,Q9NS69,O14925,O95831,Q7Z3T8,O60830,O60725,P40855,Q5JRX3,Q99595,Q15629,Q10713,Q9Y5M8,P43307,Q15005,Q6ZWJ1,Q7Z3B4,Q99797,O95429,P55786,Q8N4H5,P31751,Q12955,O96008,P46379,Q9H9H4 | Processes and pathways | GO Biological process | msigdb_gobp | 504,379,3,513,268,541,24,26,287,169,51,63,462,467,74,204,477,217,481,220,99,237,116,506,369,120,261 | 2003,597,2170,1304,527,513,1829,654,1744,871,26,24,1144,1583,974,1746,739,220,1625,268,369,1943,1089,2900,2180,2544,1591,1421,1593,2609,116,1951,847,2362,2590,287,74,120,2327,721,1790,1912,2224,2591,99,698,2831,504,2257,2105,2465,1321,2392,2259,881,379,462,506,1756,204,957,63,2336,701,1803,1386,169,477,1257,217,541,1925,607,1531,237,2301,3020,1298,705,1359,51,481,1541,261,2858,3,1001,817,1934,818,838,733,1544,1212,2622,2271,1546,2968,2166,926,2908,467 | -0.38498514034941356,0.6367609840083165,-0.47808490468523474,0.04733436242856619,0.7218675610316574,0.7430608810149629,-0.2696675832309689,0.5725751879550428,-0.22385997559133067,0.3781239970118069,3.0918170578907094,3.2734630387792905,0.15856954701810255,-0.13277690412101875,0.2907569811734416,-0.22385997559133067,0.48650845797534237,1.364397823611464,-0.1554820011028002,1.2013248973084056,0.9948692957811976,-0.3387194179434577,0.20278640880196533,-1.3291786390974751,-0.47808490468523474,-0.7382051822514453,-0.13277690412101875,-0.019893426729216315,-0.13277690412101875,-0.8102444399713625,1.8432737329874895,-0.3387194179434577,0.3998733474246863,-0.5955577777283037,-0.7861770917100085,1.1602705337166455,2.1930794944350143,1.803929707635828,-0.5719634057535422,0.5080778484189623,-0.24674132056841452,-0.3156562729795899,-0.501480515213417,-0.7861770917100085,1.9412079120317214,0.5296119487856337,-1.1283078220968537,0.7642212825740413,-0.524925194185422,-0.4314392761759522,-0.6666471270313368,0.04733436242856619,-0.6192028971632252,-0.524925194185422,0.3781239970118069,0.9740581370180955,0.8275069838030819,0.7642212825740413,-0.22385997559133067,1.4250891645523671,0.31265467698410715,2.3271166761662077,-0.5719634057535422,0.5296119487856337,-0.24674132056841452,0.0025570802874198603,1.5457402004209786,0.8064441353972578,0.09194865127890278,1.3846557563241517,0.7218675610316574,-0.3156562729795899,0.6367609840083165,-0.08749607248094354,1.3034573165650833,-0.5484193521639549,-2.3779524292893517,0.06966173419709126,0.5296119487856337,0.02496624326774895,2.5167589592971633,0.8064441353972578,-0.08749607248094354,1.2422635378120828,-1.1781401567013674,5.592463933325356,0.2907569811734416,0.443262882592413,-0.3156562729795899,0.443262882592413,0.42158622887203256,0.5080778484189623,-0.08749607248094354,0.13640227399311802,-0.8102444399713625,-0.524925194185422,-0.08749607248094354,-1.6386999972988514,-0.45473795795566646,0.3563379335731602,-1.3291786390974751,0.8275069838030819 | 3,053 |
Positive regulation of i kappab kinase nf kappab signaling | 11 | 38 | 2.456181 | 0.014042 | P37198,P09601,Q8IUH4,O15111,O43657,P19474,Q7Z434,Q8TB61,Q13546,O60826,O14920 | Processes and pathways | GO Biological process | msigdb_gobp | 324,11,12,165,322,269,245,178,276,274,127 | 127,165,322,274,1907,1308,903,2966,2689,11,269,2360,1149,1878,324,2830,1915,985,336,849,1489,276,1167,245,1926,915,12,178,2731,1767,962,1855,2239,969,1899,1650,3011,2311 | 1.764486885826947,1.5457402004209786,1.077809379742811,1.1808122620382033,-0.3156562729795899,0.04733436242856619,0.3563379335731602,-1.6386999972988514,-0.90706803754792,3.9307710524391237,1.2013248973084056,-0.5955577777283037,0.15856954701810255,-0.29263911521091057,1.077809379742811,-1.1283078220968537,-0.3156562729795899,0.2907569811734416,1.0571196890420318,0.3998733474246863,-0.06491969310546976,1.1808122620382033,0.15856954701810255,1.2830877377617704,-0.3156562729795899,0.3563379335731602,3.8432367226477653,1.5056302422299026,-0.9558195614505496,-0.22385997559133067,0.31265467698410715,-0.2696675832309689,-0.501480515213417,0.31265467698410715,-0.29263911521091057,-0.1554820011028002,-2.208082203637423,-0.5484193521639549 | 3,053 |
Guanyl nucleotide exchange factor activity | 9 | 29 | 2.446343 | 0.014431 | O95714,P80303,Q9Y4G8,Q92888,P49770,Q9NR50,Q9HAD4,Q92974,Q9P258 | Functions | GO Molecular function | msigdb_gomf | 501,6,39,586,174,180,510,612,712 | 501,1453,2386,1748,1149,174,6,699,1489,1601,1758,1045,1436,2193,2438,1292,586,612,1056,1854,510,1138,1032,180,712,1858,1184,1578,39 | 0.7642212825740413,-0.04238558185808609,-0.6192028971632252,-0.22385997559133067,0.15856954701810255,1.5256984857604572,4.634651518603069,0.5296119487856337,-0.06491969310546976,-0.13277690412101875,-0.22385997559133067,0.24684817531299486,-0.019893426729216315,-0.47808490468523474,-0.6428991995691181,0.06966173419709126,0.6580880397299336,0.6367609840083165,0.24684817531299486,-0.2696675832309689,0.7642212825740413,0.1806975002667812,0.26882156691646053,1.5056302422299026,0.5296119487856337,-0.2696675832309689,0.15856954701810255,-0.11011503607208795,2.6856565412040596 | 3,053 |
Progressive external ophthalmoplegia | 6 | 8 | 2.407047 | 0.016082 | Q07021,P51530,P12235,P03915,P03886,O60313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 105,203,488,487,177,402 | 402,578,177,487,488,1315,203,105 | 0.9323432018484419,0.6580880397299336,1.5056302422299026,0.7853489674913086,0.7853489674913086,0.04733436242856619,1.4250891645523671,1.9216692731632823 | 3,053 |
transferase | 9 | 31 | 2.39978 | 0.016405 | O14880,P43490,Q9NRN7,Q06203,Q06520,O14735,P25325,O15217,Q2TAA5 | Functions | Panther Protein class | panther_protein_class | 400,2,172,141,14,423,50,86,277 | 423,400,86,2687,2911,2217,2276,2181,1784,906,50,1978,2650,1346,2,1116,1428,931,141,14,1350,277,478,561,1399,2526,2837,894,172,2636,787 | 0.8905035560094133,0.9323432018484419,2.0966674446159113,-0.90706803754792,-1.3545835464867986,-0.501480515213417,-0.5484193521639549,-0.47808490468523474,-0.24674132056841452,0.3563379335731602,2.5167589592971633,-0.36182891654219795,-0.8585443854221945,0.02496624326774895,5.640916361417248,0.1806975002667812,-0.019893426729216315,0.3345149101794884,1.7051352372846358,3.666989822854212,0.02496624326774895,1.1808122620382033,0.8064441353972578,0.7006411186565148,0.0025570802874198603,-0.7142996591987354,-1.1283078220968537,0.3781239970118069,1.5457402004209786,-0.8343667044836434,0.4649035470490806 | 3,053 |
Gene silencing by rna | 20 | 43 | 2.399031 | 0.016439 | Q92600,P22626,Q13546,P40763,O75569,O75844,P17844,Q9HAV4,Q14671,P55265,P51114,Q06787,Q9BWF3,Q8WYQ5,Q01085,Q9UGR2,Q9Y2W6,P42694,O00571,Q9HCE1 | Processes and pathways | GO Biological process | msigdb_gobp | 647,391,276,405,528,45,696,208,583,460,221,850,231,888,627,107,108,489,737,511 | 868,737,1367,528,45,2008,2275,1313,696,391,1555,405,489,221,460,2894,1348,627,1719,1096,850,1017,1600,276,583,1685,1437,2864,1638,1492,2552,888,647,995,1133,1360,231,1501,208,511,107,1243,108 | 0.3781239970118069,0.48650845797534237,0.0025570802874198603,0.7218675610316574,2.5920285763758244,-0.38498514034941356,-0.5484193521639549,0.04733436242856619,0.5296119487856337,0.9532161662596518,-0.11011503607208795,0.9323432018484419,0.7853489674913086,1.364397823611464,0.8275069838030819,-1.303841118998535,0.02496624326774895,0.6153999674831028,-0.20102320141396507,0.20278640880196533,0.3998733474246863,0.26882156691646053,-0.13277690412101875,1.1808122620382033,0.6580880397299336,-0.17823065580578884,-0.019893426729216315,-1.2031510377233365,-0.1554820011028002,-0.06491969310546976,-0.7382051822514453,0.3781239970118069,0.5940047747374697,0.2907569811734416,0.1806975002667812,0.02496624326774895,1.3237987550526746,-0.06491969310546976,1.4048861540431081,0.7642212825740413,1.9216692731632823,0.11419540272429664,1.9216692731632823 | 3,053 |
Increased susceptibility to fractures | 13 | 52 | 2.395536 | 0.016596 | Q13126,P39210,Q14739,O95453,P48735,P22626,Q96AY3,Q13501,P22681,O15269,O75874,P40763,Q6DD88 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 259,0,193,469,121,391,46,47,234,249,90,405,474 | 2685,249,653,2798,1971,844,90,1478,469,976,1311,2275,2417,1783,1271,1344,1831,822,2385,391,234,2667,2547,1878,0,405,1980,121,1792,848,2549,1198,1162,1797,259,47,2070,1756,2108,193,1565,474,609,2443,46,2596,544,999,966,1773,1739,867 | -0.90706803754792,1.262689863668224,0.5725751879550428,-1.078723901896545,-0.36182891654219795,0.3998733474246863,2.0385454239533916,-0.06491969310546976,0.8064441353972578,0.2907569811734416,0.04733436242856619,-0.5484193521639549,-0.6428991995691181,-0.24674132056841452,0.06966173419709126,0.02496624326774895,-0.2696675832309689,0.42158622887203256,-0.6192028971632252,0.9532161662596518,1.3034573165650833,-0.8827779909790987,-0.7382051822514453,-0.29263911521091057,6.790697148136532,0.9323432018484419,-0.36182891654219795,1.803929707635828,-0.24674132056841452,0.3998733474246863,-0.7382051822514453,0.13640227399311802,0.15856954701810255,-0.24674132056841452,1.2422635378120828,2.573242040306225,-0.4081884661759546,-0.22385997559133067,-0.4314392761759522,1.4452649342552104,-0.11011503607208795,0.8064441353972578,0.6367609840083165,-0.6428991995691181,2.5920285763758244,-0.7861770917100085,0.7218675610316574,0.2907569811734416,0.31265467698410715,-0.22385997559133067,-0.20102320141396507,0.3998733474246863 | 3,053 |
Protein autoubiquitination | 8 | 14 | 2.392018 | 0.016756 | Q96J02,Q5VTB9,O95628,P22681,P19474,Q9ULT8,Q5W0B1,P38398 | Processes and pathways | GO Biological process | msigdb_gobp | 752,702,15,234,269,675,216,624 | 1010,15,269,234,624,1433,1491,702,216,752,833,2449,675,1302 | 0.26882156691646053,3.5960411197517193,1.2013248973084056,1.3034573165650833,0.6153999674831028,-0.019893426729216315,-0.06491969310546976,0.5296119487856337,1.3846557563241517,0.48650845797534237,0.42158622887203256,-0.6428991995691181,0.5725751879550428,0.06966173419709126 | 3,053 |
Zinc finger, RING-type, conserved site [IPR017907] | 9 | 13 | 2.365659 | 0.017998 | Q9UBS8,P22681,O75150,P19474,Q99590,O95376,Q99496,P38398,Q14527 | Sequence | InterPro Conserved site | interpro_conserved_site | 66,234,456,269,251,739,705,624,569 | 1140,456,739,269,234,624,1167,569,833,705,251,66,2086 | 0.15856954701810255,0.8275069838030819,0.48650845797534237,1.2013248973084056,1.3034573165650833,0.6153999674831028,0.15856954701810255,0.6793813477027839,0.42158622887203256,0.5296119487856337,1.262689863668224,2.2889304994100175,-0.4081884661759546 | 3,053 |
Zinc finger, RING-type [IPR001841] | 13 | 23 | 2.34082 | 0.019241 | Q9UBS8,P38398,Q5VTB9,O95628,O96028,P19474,O75150,P22681,O95376,Q5W0B1,Q99496,Q99590,Q14527 | Sequence | InterPro Domain | interpro_domain | 66,624,702,15,682,269,456,234,739,216,705,251,569 | 1140,456,1010,739,15,682,269,234,624,1721,1602,1167,569,702,216,2594,833,705,251,66,2085,2086,2411 | 0.15856954701810255,0.8275069838030819,0.26882156691646053,0.48650845797534237,3.5960411197517193,0.5511109868815428,1.2013248973084056,1.3034573165650833,0.6153999674831028,-0.20102320141396507,-0.13277690412101875,0.15856954701810255,0.6793813477027839,0.5296119487856337,1.3846557563241517,-0.7861770917100085,0.42158622887203256,0.5296119487856337,1.262689863668224,2.2889304994100175,-0.4081884661759546,-0.4081884661759546,-0.6192028971632252 | 3,053 |
RNA-mediated gene silencing | 9 | 16 | 2.327586 | 0.019934 | Q06787,Q92600,O75569,Q9BWF3,Q9Y2W6,Q9HAV4,A5YKK6,P55265,Q9HCE1 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 850,647,528,231,108,208,868,460,511 | 868,1367,528,460,850,1600,1796,1492,647,995,231,1501,208,511,1243,108 | 0.3781239970118069,0.0025570802874198603,0.7218675610316574,0.8275069838030819,0.3998733474246863,-0.13277690412101875,-0.24674132056841452,-0.06491969310546976,0.5940047747374697,0.2907569811734416,1.3237987550526746,-0.06491969310546976,1.4048861540431081,0.7642212825740413,0.11419540272429664,1.9216692731632823 | 3,053 |
Transmembrane transport | 43 | 211 | 2.322501 | 0.020206 | P39210,Q00535,P04920,Q9NS69,Q8IXU6,O00186,P38435,P23786,Q8IUH4,O95831,P21796,Q9NV96,Q9HD26,O60830,Q13546,P52789,Q8NEW0,P45880,Q8WTV0,Q70HW3,Q9UHG3,O75844,Q99595,Q8TB61,Q9BSK2,Q9C0H2,Q15629,Q9Y277,Q7L0J3,Q96PU5,Q9UBX3,P62942,P41440,Q7KZN9,O43772,P08183,O96008,Q96ES6,Q9Y619,Q9HC21,O75964,P31751,Q9H2D1 | Processes and pathways | GO Biological process | msigdb_gobp | 0,379,378,3,133,254,262,130,12,268,20,282,281,24,276,156,157,32,34,35,37,45,51,178,56,320,63,68,340,80,81,336,334,89,211,92,369,96,104,103,112,116,119 | 1775,254,2684,715,1742,1778,513,654,695,211,1114,1448,2560,24,499,1307,2538,2126,1872,1144,1583,2890,45,2414,1038,112,1746,1584,268,369,578,487,1311,378,2010,2784,1712,2357,1479,1415,2840,2179,2012,2482,92,1586,599,2358,2940,2277,2900,2383,502,488,719,1747,1553,656,2385,1833,1419,2421,2513,2360,20,130,1192,2841,1593,796,2282,1877,622,1950,116,877,2097,3036,1372,2423,262,1115,0,334,1596,32,1373,2953,1952,1790,1912,1485,2135,1792,156,1750,1953,1983,1320,1914,2066,2489,2831,2257,2427,2105,1321,336,1117,2886,1322,379,2833,1161,534,1162,1841,1377,2928,850,800,2672,2138,506,802,276,830,1524,2432,723,957,663,63,2494,1384,1350,1803,664,2969,1229,1988,539,2440,477,35,89,340,607,12,608,133,1130,1533,2932,1173,1534,157,646,178,1535,34,2700,1811,96,1206,1690,80,1296,1298,2878,1359,51,2779,481,863,2343,1264,56,1853,1895,1540,320,2269,2501,119,1242,1856,2858,1447,103,399,281,3,282,2122,81,635,818,733,37,512,1699,1002,2681,2917,68,2475,2166,2211,104,841 | -0.24674132056841452,1.2422635378120828,-0.90706803754792,0.5080778484189623,-0.22385997559133067,-0.24674132056841452,0.7430608810149629,0.5725751879550428,0.5296119487856337,1.3846557563241517,0.1806975002667812,-0.04238558185808609,-0.7621641673616228,3.2734630387792905,0.7642212825740413,0.04733436242856619,-0.7382051822514453,-0.45473795795566646,-0.29263911521091057,0.15856954701810255,-0.13277690412101875,-1.303841118998535,2.5920285763758244,-0.6428991995691181,0.24684817531299486,1.882519935756883,-0.22385997559133067,-0.13277690412101875,1.2013248973084056,0.9948692957811976,0.6580880397299336,0.7853489674913086,0.04733436242856619,0.9740581370180955,-0.38498514034941356,-1.0540235788334475,-0.20102320141396507,-0.5955577777283037,-0.06491969310546976,-0.019893426729216315,-1.1531926286514946,-0.47808490468523474,-0.38498514034941356,-0.6904471283524107,2.0191249668757036,-0.13277690412101875,0.6367609840083165,-0.5955577777283037,-1.4826444366763971,-0.5484193521639549,-1.3291786390974751,-0.6192028971632252,0.7642212825740413,0.7853489674913086,0.5080778484189623,-0.22385997559133067,-0.11011503607208795,0.5725751879550428,-0.6192028971632252,-0.2696675832309689,-0.019893426729216315,-0.6428991995691181,-0.7142996591987354,-0.5955577777283037,3.381602740630259,1.7447281172585196,0.13640227399311802,-1.1531926286514946,-0.13277690412101875,0.443262882592413,-0.5484193521639549,-0.29263911521091057,0.6153999674831028,-0.3387194179434577,1.8432737329874895,0.3781239970118069,-0.4314392761759522,-2.905742682929943,0.0025570802874198603,-0.6428991995691181,1.2218086022023797,0.1806975002667812,6.790697148136532,1.0571196890420318,-0.13277690412101875,2.8158980590558365,0.0025570802874198603,-1.534366639104802,-0.3387194179434577,-0.24674132056841452,-0.3156562729795899,-0.06491969310546976,-0.45473795795566646,-0.24674132056841452,1.585744595846163,-0.22385997559133067,-0.3387194179434577,-0.36182891654219795,0.04733436242856619,-0.3156562729795899,-0.4081884661759546,-0.6904471283524107,-1.1283078220968537,-0.524925194185422,-0.6428991995691181,-0.4314392761759522,0.04733436242856619,1.0571196890420318,0.1806975002667812,-1.278570283055428,0.04733436242856619,0.9740581370180955,-1.1283078220968537,0.15856954701810255,0.7218675610316574,0.15856954701810255,-0.2696675832309689,0.0025570802874198603,-1.4312098217663123,0.3998733474246863,0.443262882592413,-0.8827779909790987,-0.45473795795566646,0.7642212825740413,0.443262882592413,1.1808122620382033,0.42158622887203256,-0.08749607248094354,-0.6428991995691181,0.5080778484189623,0.31265467698410715,0.5725751879550428,2.3271166761662077,-0.6904471283524107,0.0025570802874198603,0.02496624326774895,-0.24674132056841452,0.5725751879550428,-1.6649735266333288,0.11419540272429664,-0.36182891654219795,0.7218675610316574,-0.6428991995691181,0.8064441353972578,2.7415926503073877,2.0579425824732125,1.0571196890420318,0.6367609840083165,3.8432367226477653,0.6367609840083165,1.7447281172585196,0.1806975002667812,-0.08749607248094354,-1.4312098217663123,0.15856954701810255,-0.08749607248094354,1.585744595846163,0.5940047747374697,1.5056302422299026,-0.08749607248094354,2.760198415947888,-0.90706803754792,-0.24674132056841452,1.9607226861740548,0.13640227399311802,-0.17823065580578884,2.154582729798314,0.06966173419709126,0.06966173419709126,-1.2533654408572235,0.02496624326774895,2.5167589592971633,-1.0293835579205086,0.8064441353972578,0.3998733474246863,-0.5719634057535422,0.09194865127890278,2.422203483979085,-0.2696675832309689,-0.29263911521091057,-0.08749607248094354,1.0984691394737887,-0.524925194185422,-0.6904471283524107,1.8236140086064396,0.11419540272429664,-0.2696675832309689,-1.1781401567013674,-0.019893426729216315,1.9412079120317214,0.9532161662596518,1.1808122620382033,5.592463933325356,1.1808122620382033,-0.4314392761759522,2.154582729798314,0.6153999674831028,0.443262882592413,0.5080778484189623,2.722967138304573,0.7642212825740413,-0.17823065580578884,0.2907569811734416,-0.8827779909790987,-1.3545835464867986,2.2314864977762854,-0.6666471270313368,-0.45473795795566646,-0.47808490468523474,1.9412079120317214,0.42158622887203256 | 3,053 |
Nucleotide transmembrane transporter activity | 7 | 12 | 2.322089 | 0.020228 | Q9HC21,P12236,P12235,Q8TB61,P41440,Q9H2D1,Q9BSK2 | Functions | GO Molecular function | msigdb_gomf | 103,719,488,178,334,119,56 | 715,1114,1712,488,719,334,1229,178,863,56,119,103 | 0.5080778484189623,0.1806975002667812,-0.20102320141396507,0.7853489674913086,0.5080778484189623,1.0571196890420318,0.11419540272429664,1.5056302422299026,0.3998733474246863,2.422203483979085,1.8236140086064396,1.9412079120317214 | 3,053 |
Organophosphate ester transmembrane transporter activity | 7 | 12 | 2.322089 | 0.020228 | Q9HC21,P12236,P12235,Q8TB61,P41440,Q9H2D1,Q9BSK2 | Functions | GO Molecular function | msigdb_gomf | 103,719,488,178,334,119,56 | 715,1114,1712,488,719,334,1229,178,863,56,119,103 | 0.5080778484189623,0.1806975002667812,-0.20102320141396507,0.7853489674913086,0.5080778484189623,1.0571196890420318,0.11419540272429664,1.5056302422299026,0.3998733474246863,2.422203483979085,1.8236140086064396,1.9412079120317214 | 3,053 |
Negative regulation of neuron projection development | 6 | 18 | 2.306368 | 0.02109 | Q00535,Q8N0X7,Q9NQC3,Q96G23,Q86X55,Q9UL15 | Processes and pathways | GO Biological process | msigdb_gobp | 379,77,312,29,350,253 | 2581,1312,2360,2609,2062,985,1458,379,1679,1254,396,350,77,1328,29,312,2530,253 | -0.7861770917100085,0.04733436242856619,-0.5955577777283037,-0.8102444399713625,-0.4081884661759546,0.2907569811734416,-0.04238558185808609,0.9740581370180955,-0.17823065580578884,0.09194865127890278,0.9532161662596518,1.036399894714161,2.1738423843041677,0.04733436242856619,2.9451879305659427,1.1190991391688916,-0.7142996591987354,1.262689863668224 | 3,053 |
Intrinsic component of mitochondrial inner membrane | 12 | 29 | 2.297335 | 0.0216 | Q9HC21,Q9Y2R0,Q9NVH1,Q9UG56,O14925,Q9H3K2,Q15070,Q99595,Q16134,Q6P4A7,O60830,Q5XKP0 | Localization | GO Cellular component | msigdb_gocc | 103,201,432,343,513,272,628,51,584,539,24,538 | 513,2049,24,2688,2052,2871,1071,1322,1119,628,584,1351,1386,538,539,1126,1534,1690,51,2597,272,1856,103,432,710,343,201,2211,926 | 0.7430608810149629,-0.4081884661759546,3.2734630387792905,-0.90706803754792,-0.4081884661759546,-1.2282259143903864,0.22483654434088843,0.04733436242856619,0.1806975002667812,0.6153999674831028,0.6580880397299336,0.02496624326774895,0.0025570802874198603,0.7218675610316574,0.7218675610316574,0.1806975002667812,-0.08749607248094354,-0.17823065580578884,2.5167589592971633,-0.7861770917100085,1.2013248973084056,-0.2696675832309689,1.9412079120317214,0.8905035560094133,0.5296119487856337,1.0571196890420318,1.4452649342552104,-0.47808490468523474,0.3563379335731602 | 3,053 |
Dsrna processing | 9 | 21 | 2.287189 | 0.022185 | O75569,P17844,Q9UGR2,P22626,O75844,Q14671,P55265,Q13546,P40763 | Processes and pathways | GO Biological process | msigdb_gobp | 528,696,107,391,45,583,460,276,405 | 737,528,45,2008,2275,696,391,405,460,1719,1017,276,583,1685,1638,1492,888,1360,1501,107,1243 | 0.48650845797534237,0.7218675610316574,2.5920285763758244,-0.38498514034941356,-0.5484193521639549,0.5296119487856337,0.9532161662596518,0.9323432018484419,0.8275069838030819,-0.20102320141396507,0.26882156691646053,1.1808122620382033,0.6580880397299336,-0.17823065580578884,-0.1554820011028002,-0.06491969310546976,0.3781239970118069,0.02496624326774895,-0.06491969310546976,1.9216692731632823,0.11419540272429664 | 3,053 |
Regulation of gene silencing by rna | 8 | 19 | 2.281233 | 0.022535 | Q01085,O75844,Q9HAV4,Q14671,P55265,Q13546,P40763,P51114 | Processes and pathways | GO Biological process | msigdb_gobp | 627,45,208,583,460,276,405,221 | 1367,45,2008,2275,696,1555,405,221,460,627,1719,1096,850,1017,1600,276,583,1437,208 | 0.0025570802874198603,2.5920285763758244,-0.38498514034941356,-0.5484193521639549,0.5296119487856337,-0.11011503607208795,0.9323432018484419,1.364397823611464,0.8275069838030819,0.6153999674831028,-0.20102320141396507,0.20278640880196533,0.3998733474246863,0.26882156691646053,-0.13277690412101875,1.1808122620382033,0.6580880397299336,-0.019893426729216315,1.4048861540431081 | 3,053 |
Ankyrin repeat-containing domain superfamily [IPR036770] | 8 | 18 | 2.27962 | 0.02263 | Q6W2J9,O75832,Q9H6S0,Q8IUH4,Q9ULT8,Q92625,Q12955,Q86XL3 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 65,598,301,12,675,412,506,55 | 1085,1308,598,2480,506,912,65,55,12,412,2034,1262,2039,301,1000,711,2159,675 | 0.20278640880196533,0.04733436242856619,0.6367609840083165,-0.6904471283524107,0.7642212825740413,0.3563379335731602,2.2889304994100175,2.4600887755522476,3.8432367226477653,0.9323432018484419,-0.38498514034941356,0.09194865127890278,-0.38498514034941356,1.1396995480631378,0.2907569811734416,0.5296119487856337,-0.45473795795566646,0.5725751879550428 | 3,053 |
Inorganic anion transport | 8 | 27 | 2.271002 | 0.023147 | P45880,Q9UHG3,Q9Y277,P08183,Q9UBX3,P21796,Q9C0H2,P54105 | Processes and pathways | GO Biological process | msigdb_gobp | 32,37,68,92,81,20,320,318 | 2684,1744,378,92,2358,20,32,2135,1792,318,1914,1322,1161,2432,664,2931,2969,1573,1895,320,590,525,2122,81,37,68,841 | -0.90706803754792,-0.22385997559133067,0.9740581370180955,2.0191249668757036,-0.5955577777283037,3.381602740630259,2.8158980590558365,-0.45473795795566646,-0.24674132056841452,1.0984691394737887,-0.3156562729795899,0.04733436242856619,0.15856954701810255,-0.6428991995691181,0.5725751879550428,-1.4312098217663123,-1.6649735266333288,-0.11011503607208795,-0.29263911521091057,1.0984691394737887,0.6580880397299336,0.7430608810149629,-0.4314392761759522,2.154582729798314,2.722967138304573,2.2314864977762854,0.42158622887203256 | 3,053 |
Micromelia | 6 | 20 | 2.261353 | 0.023737 | Q14739,P25054,Q15392,O43175,O75874,P48735 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 193,258,4,18,90,121 | 18,1217,1907,2453,844,90,1831,258,121,2892,744,2777,193,4,2075,921,837,283,2780,2918 | 3.4712462788072194,0.11419540272429664,-0.3156562729795899,-0.6666471270313368,0.3998733474246863,2.0385454239533916,-0.2696675832309689,1.2422635378120828,1.803929707635828,-1.303841118998535,0.48650845797534237,-1.0293835579205086,1.4452649342552104,5.036022265834179,-0.4081884661759546,0.3563379335731602,0.42158622887203256,1.1808122620382033,-1.0293835579205086,-1.3545835464867986 | 3,053 |
Posterior embryotoxon | 7 | 17 | 2.25843 | 0.023919 | P40855,P54198,P53701,Q12948,Q92766,Q7LGA3,P21964 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 287,236,175,176,122,478,225 | 1144,225,1979,287,1912,175,932,236,1718,176,1046,478,888,122,2033,2085,595 | 0.15856954701810255,1.3441122067215945,-0.36182891654219795,1.1602705337166455,-0.3156562729795899,1.5256984857604572,0.3345149101794884,1.3034573165650833,-0.20102320141396507,1.5256984857604572,0.24684817531299486,0.8064441353972578,0.3781239970118069,1.803929707635828,-0.38498514034941356,-0.4081884661759546,0.6580880397299336 | 3,053 |
Regulation of dendrite development | 8 | 20 | 2.234061 | 0.025479 | Q9Y4G8,Q12834,Q96PU5,P98155,Q7L576,Q9UQB8,Q86X55,Q16643 | Processes and pathways | GO Biological process | msigdb_gobp | 39,359,80,626,440,53,350,537 | 1780,2062,2773,660,985,1458,626,1841,1017,359,1435,537,440,350,80,1855,1859,1301,53,39 | -0.24674132056841452,-0.4081884661759546,-1.0293835579205086,0.5725751879550428,0.2907569811734416,-0.04238558185808609,0.6153999674831028,-0.2696675832309689,0.26882156691646053,1.0156498223536288,-0.019893426729216315,0.7218675610316574,0.8695365017538665,1.036399894714161,2.154582729798314,-0.2696675832309689,-0.2696675832309689,0.06966173419709126,2.4789997780015374,2.6856565412040596 | 3,053 |
Mitochondrial transport | 14 | 75 | 2.219865 | 0.026428 | P45880,Q9NS69,Q5JRX3,P55786,P23786,Q14849,Q8N4H5,Q9UBX3,O75964,Q99595,O60830,O43772,P52789,O95429 | Processes and pathways | GO Biological process | msigdb_gobp | 32,3,169,99,130,70,237,81,112,51,24,211,156,220 | 527,513,1829,654,211,24,2688,1583,1038,112,1746,739,220,1625,268,369,2275,1712,1479,1943,1552,2900,488,2544,130,1192,2841,2282,1978,2362,1372,2789,32,2953,2327,1790,2591,156,99,2066,2489,881,800,462,70,628,957,2336,1803,1386,169,1229,1925,1022,2144,237,2301,832,1330,705,51,481,1541,2858,3,817,1934,81,1544,1699,1002,2948,2968,926,2908 | 0.7218675610316574,0.7430608810149629,-0.2696675832309689,0.5725751879550428,1.3846557563241517,3.2734630387792905,-0.90706803754792,-0.13277690412101875,0.24684817531299486,1.882519935756883,-0.22385997559133067,0.48650845797534237,1.364397823611464,-0.1554820011028002,1.2013248973084056,0.9948692957811976,-0.5484193521639549,-0.20102320141396507,-0.06491969310546976,-0.3387194179434577,-0.11011503607208795,-1.3291786390974751,0.7853489674913086,-0.7382051822514453,1.7447281172585196,0.13640227399311802,-1.1531926286514946,-0.5484193521639549,-0.36182891654219795,-0.5955577777283037,0.0025570802874198603,-1.0540235788334475,2.8158980590558365,-1.534366639104802,-0.5719634057535422,-0.24674132056841452,-0.7861770917100085,1.585744595846163,1.9412079120317214,-0.4081884661759546,-0.6904471283524107,0.3781239970118069,0.443262882592413,0.8275069838030819,2.2122941644519587,0.6153999674831028,0.31265467698410715,-0.5719634057535422,-0.24674132056841452,0.0025570802874198603,1.5457402004209786,0.11419540272429664,-0.3156562729795899,0.26882156691646053,-0.45473795795566646,1.3034573165650833,-0.5484193521639549,0.42158622887203256,0.04733436242856619,0.5296119487856337,2.5167589592971633,0.8064441353972578,-0.08749607248094354,-1.1781401567013674,5.592463933325356,0.443262882592413,-0.3156562729795899,2.154582729798314,-0.08749607248094354,-0.17823065580578884,0.2907569811734416,-1.508469190198362,-1.6386999972988514,0.3563379335731602,-1.3291786390974751 | 3,053 |
I kappab kinase nf kappab signaling | 12 | 53 | 2.217137 | 0.026614 | P37198,P09601,Q8IUH4,O15111,O43657,Q13501,P19474,Q7Z434,Q8TB61,Q13546,O60826,O14920 | Processes and pathways | GO Biological process | msigdb_gobp | 324,11,12,165,322,47,269,245,178,276,274,127 | 127,165,322,274,1907,1087,1308,2380,903,2966,2689,3023,11,269,2360,1149,1950,1878,324,1070,2830,1915,985,336,849,1489,883,47,276,987,1167,1722,439,245,1926,915,1846,12,178,2731,1767,962,1358,921,1691,1855,2239,969,1899,732,1650,3011,2311 | 1.764486885826947,1.5457402004209786,1.077809379742811,1.1808122620382033,-0.3156562729795899,0.20278640880196533,0.04733436242856619,-0.6192028971632252,0.3563379335731602,-1.6386999972988514,-0.90706803754792,-2.4640563858494313,3.9307710524391237,1.2013248973084056,-0.5955577777283037,0.15856954701810255,-0.3387194179434577,-0.29263911521091057,1.077809379742811,0.22483654434088843,-1.1283078220968537,-0.3156562729795899,0.2907569811734416,1.0571196890420318,0.3998733474246863,-0.06491969310546976,0.3781239970118069,2.573242040306225,1.1808122620382033,0.2907569811734416,0.15856954701810255,-0.20102320141396507,0.8695365017538665,1.2830877377617704,-0.3156562729795899,0.3563379335731602,-0.2696675832309689,3.8432367226477653,1.5056302422299026,-0.9558195614505496,-0.22385997559133067,0.31265467698410715,0.02496624326774895,0.3563379335731602,-0.17823065580578884,-0.2696675832309689,-0.501480515213417,0.31265467698410715,-0.29263911521091057,0.5080778484189623,-0.1554820011028002,-2.208082203637423,-0.5484193521639549 | 3,053 |
Skin rash | 7 | 19 | 2.210807 | 0.027049 | Q14739,P18074,Q06136,Q9H4L7,P22681,Q13546,P40763 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 193,285,8,238,234,276,405 | 434,285,1039,845,234,1148,2017,405,2819,1984,2257,8,276,193,1608,1807,781,238,2637 | 0.8695365017538665,1.1602705337166455,0.24684817531299486,0.3998733474246863,1.3034573165650833,0.15856954701810255,-0.38498514034941356,0.9323432018484419,-1.1034851164802537,-0.36182891654219795,-0.524925194185422,4.242764840201137,1.1808122620382033,1.4452649342552104,-0.13277690412101875,-0.24674132056841452,0.4649035470490806,1.3034573165650833,-0.8343667044836434 | 3,053 |
K Homology domain, type 1 [IPR004088] | 13 | 23 | 2.200554 | 0.027768 | Q92667,Q9NQT5,P61978,Q96I24,Q15365,Q96PU8,Q9Y2W6,Q07666,Q92945,Q15366,Q96AE4,P51114,P51116 | Sequence | InterPro Domain | interpro_domain | 128,484,661,366,381,690,108,491,179,856,808,221,192 | 2351,1308,221,192,661,2331,850,491,2107,381,856,1606,1535,128,179,808,366,690,484,1995,2045,108,1865 | -0.5955577777283037,0.04733436242856619,1.364397823611464,1.4452649342552104,0.5725751879550428,-0.5719634057535422,0.3998733474246863,0.7853489674913086,-0.4314392761759522,0.9740581370180955,0.3998733474246863,-0.13277690412101875,-0.08749607248094354,1.764486885826947,1.5056302422299026,0.443262882592413,1.0156498223536288,0.5511109868815428,0.8064441353972578,-0.36182891654219795,-0.38498514034941356,1.9216692731632823,-0.2696675832309689 | 3,053 |
Mitochondrial respiratory chain complex assembly | 9 | 36 | 2.195549 | 0.028124 | O75306,Q9Y2R0,O95831,O43676,P03886,O75438,Q9H061,Q9BSK2,Q6DKK2 | Processes and pathways | GO Biological process | msigdb_gobp | 228,201,268,111,177,54,23,56,88 | 111,2049,2126,228,54,1145,2052,1711,873,1220,268,1830,177,487,2985,879,1431,628,663,2618,1564,88,364,1171,861,1264,56,1692,23,2120,2634,817,2948,201,926,2376 | 1.882519935756883,-0.4081884661759546,-0.45473795795566646,1.3237987550526746,2.4600887755522476,0.15856954701810255,-0.4081884661759546,-0.20102320141396507,0.3781239970118069,0.11419540272429664,1.2013248973084056,-0.2696675832309689,1.5056302422299026,0.7853489674913086,-1.9593339662988416,0.3781239970118069,-0.019893426729216315,0.6153999674831028,0.5725751879550428,-0.8102444399713625,-0.11011503607208795,2.0579425824732125,1.0156498223536288,0.15856954701810255,0.3998733474246863,0.09194865127890278,2.422203483979085,-0.17823065580578884,3.291529859154659,-0.4314392761759522,-0.8343667044836434,0.443262882592413,-1.508469190198362,1.4452649342552104,0.3563379335731602,-0.5955577777283037 | 3,053 |
Amide binding | 24 | 100 | 2.183562 | 0.028994 | Q15392,P24390,P00374,P21796,Q02252,Q9Y680,O43731,P45880,Q8WTV0,P40855,Q96AY3,P35610,Q92973,Q9NZ08,Q00169,P62942,P41440,Q9NZJ7,Q9UIQ6,Q9BYT8,P55786,P52948,P10321,Q96CW1 | Functions | GO Molecular function | msigdb_gomf | 4,13,16,20,151,27,31,32,34,287,46,294,309,185,325,336,334,354,94,367,99,235,370,384 | 946,617,899,2639,2312,2899,2910,2507,31,1623,790,2478,1746,16,2988,2824,2641,3003,2250,638,1975,1480,2605,370,2998,1452,906,20,2646,2667,13,1274,2742,2282,1422,2515,294,771,2590,287,2691,334,741,32,2726,983,392,1153,1912,2819,2518,1093,235,99,2257,2105,1073,336,1957,325,1016,151,1679,534,2872,1017,2395,1920,1044,2397,2994,957,4,604,859,34,3020,1891,309,46,384,2983,1574,2779,2526,1401,367,1694,575,2120,2530,185,354,838,1268,94,2947,1365,2088,27 | 0.31265467698410715,0.6153999674831028,0.3563379335731602,-0.8585443854221945,-0.5719634057535422,-1.3291786390974751,-1.3545835464867986,-0.7142996591987354,2.8158980590558365,-0.1554820011028002,0.443262882592413,-0.6904471283524107,-0.22385997559133067,3.542657367414011,-1.986607236530285,-1.1283078220968537,-0.8585443854221945,-2.1800797043564155,-0.524925194185422,0.5940047747374697,-0.36182891654219795,-0.06491969310546976,-0.8102444399713625,0.9948692957811976,-2.0689736218805734,-0.04238558185808609,0.3563379335731602,3.381602740630259,-0.8585443854221945,-0.8827779909790987,3.720031204508013,0.06966173419709126,-0.9802821143207153,-0.5484193521639549,-0.019893426729216315,-0.7142996591987354,1.1396995480631378,0.4649035470490806,-0.7861770917100085,1.1602705337166455,-0.90706803754792,1.0571196890420318,0.48650845797534237,2.8158980590558365,-0.9558195614505496,0.2907569811734416,0.9532161662596518,0.15856954701810255,-0.3156562729795899,-1.1034851164802537,-0.7142996591987354,0.20278640880196533,1.3034573165650833,1.9412079120317214,-0.524925194185422,-0.4314392761759522,0.22483654434088843,1.0571196890420318,-0.3387194179434577,1.077809379742811,0.26882156691646053,1.645555644220977,-0.17823065580578884,0.7218675610316574,-1.2282259143903864,0.26882156691646053,-0.6192028971632252,-0.3156562729795899,0.24684817531299486,-0.6192028971632252,-2.013970850691003,0.31265467698410715,5.036022265834179,0.6367609840083165,0.3998733474246863,2.760198415947888,-2.3779524292893517,-0.29263911521091057,1.1190991391688916,2.5920285763758244,0.9740581370180955,-1.8511212916446877,-0.11011503607208795,-1.0293835579205086,-0.7142996591987354,0.0025570802874198603,1.0156498223536288,-0.17823065580578884,0.6793813477027839,-0.4314392761759522,-0.7142996591987354,1.4855353300607983,1.036399894714161,0.42158622887203256,0.09194865127890278,1.9802137107360143,-1.508469190198362,0.02496624326774895,-0.4081884661759546,3.0735531405768084 | 3,053 |
K Homology domain, type 1 superfamily [IPR036612] | 14 | 25 | 2.176619 | 0.029509 | Q92667,Q9NQT5,P61978,Q9NRX1,Q96I24,Q15365,Q96PU8,Q9Y2W6,Q07666,Q92945,Q15366,Q96AE4,P51114,P51116 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 128,484,661,786,366,381,690,108,491,179,856,808,221,192 | 2351,1308,221,192,661,2331,850,491,2230,2107,381,856,1606,1535,128,179,808,366,690,484,786,1995,2045,108,1865 | -0.5955577777283037,0.04733436242856619,1.364397823611464,1.4452649342552104,0.5725751879550428,-0.5719634057535422,0.3998733474246863,0.7853489674913086,-0.501480515213417,-0.4314392761759522,0.9740581370180955,0.3998733474246863,-0.13277690412101875,-0.08749607248094354,1.764486885826947,1.5056302422299026,0.443262882592413,1.0156498223536288,0.5511109868815428,0.8064441353972578,0.4649035470490806,-0.36182891654219795,-0.38498514034941356,1.9216692731632823,-0.2696675832309689 | 3,053 |
Peripheral axonal neuropathy | 18 | 48 | 2.176275 | 0.029535 | P39210,Q9HC21,P22626,O95831,P00403,Q15067,P12235,Q9BTW9,P03915,Q9NVI7,P03886,Q9NZJ7,O15269,Q9NRG9,P40763,P07196,O60313,Q6DD88 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,103,391,268,578,338,488,544,487,546,177,354,249,352,405,655,402,474 | 249,653,1339,402,791,268,578,177,487,3023,655,2179,2250,2509,1344,488,2710,391,1876,1516,0,405,2692,1278,1485,1751,2549,2426,911,1797,2261,2433,338,991,474,1686,1727,1963,1329,1399,2343,544,103,352,546,354,2211,1413 | 1.262689863668224,0.5725751879550428,0.02496624326774895,0.9323432018484419,0.443262882592413,1.2013248973084056,0.6580880397299336,1.5056302422299026,0.7853489674913086,-2.4640563858494313,0.5725751879550428,-0.47808490468523474,-0.524925194185422,-0.7142996591987354,0.02496624326774895,0.7853489674913086,-0.9314150499140011,0.9532161662596518,-0.29263911521091057,-0.08749607248094354,6.790697148136532,0.9323432018484419,-0.90706803754792,0.06966173419709126,-0.06491969310546976,-0.22385997559133067,-0.7382051822514453,-0.6428991995691181,0.3563379335731602,-0.24674132056841452,-0.524925194185422,-0.6428991995691181,1.0571196890420318,0.2907569811734416,0.8064441353972578,-0.17823065580578884,-0.20102320141396507,-0.3387194179434577,0.04733436242856619,0.0025570802874198603,-0.5719634057535422,0.7218675610316574,1.9412079120317214,1.036399894714161,0.7218675610316574,1.036399894714161,-0.47808490468523474,0.0025570802874198603 | 3,053 |
Retinal vascular tortuosity | 6 | 14 | 2.173763 | 0.029723 | O75306,P54198,P03915,P03886,Q92766,P21964 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 228,236,487,177,122,225 | 228,177,487,225,1979,932,236,1718,1046,888,122,2033,2085,595 | 1.3237987550526746,1.5056302422299026,0.7853489674913086,1.3441122067215945,-0.36182891654219795,0.3345149101794884,1.3034573165650833,-0.20102320141396507,0.24684817531299486,0.3781239970118069,1.803929707635828,-0.38498514034941356,-0.4081884661759546,0.6580880397299336 | 3,053 |
Nuclear ubiquitin ligase complex | 9 | 14 | 2.167243 | 0.030216 | Q6W2J9,Q9UJX2,Q12834,O60566,Q16763,Q9UJX3,P38398,P30260,Q96DE5 | Localization | GO Cellular component | msigdb_gocc | 65,693,359,550,437,188,624,658,61 | 2959,550,658,624,359,437,65,61,705,965,1857,693,188,1619 | -1.5863829117981387,0.7006411186565148,0.5725751879550428,0.6153999674831028,1.0156498223536288,0.8695365017538665,2.2889304994100175,2.3461771153462627,0.5296119487856337,0.31265467698410715,-0.2696675832309689,0.5511109868815428,1.4654136081925186,-0.13277690412101875 | 3,053 |
Zinc finger C2H2-type [IPR013087] | 13 | 23 | 2.164342 | 0.030438 | Q969S3,Q96KM6,Q9ULV3,Q14966,Q96KR1,P98175,P52756,Q9UL40,Q9UNI6,Q68CP9,Q9Y467,Q92766,Q8N1G0 | Sequence | InterPro Domain | interpro_domain | 291,753,593,642,671,358,459,114,897,885,442,122,609 | 872,2094,459,358,642,1608,885,2111,1442,609,122,2444,291,1814,753,671,1694,1060,114,593,897,1366,442 | 0.3781239970118069,-0.4314392761759522,0.8275069838030819,1.0156498223536288,0.5940047747374697,-0.13277690412101875,0.3781239970118069,-0.4314392761759522,-0.019893426729216315,0.6367609840083165,1.803929707635828,-0.6428991995691181,1.1602705337166455,-0.24674132056841452,0.48650845797534237,0.5725751879550428,-0.17823065580578884,0.24684817531299486,1.882519935756883,0.6580880397299336,0.3781239970118069,0.02496624326774895,0.8695365017538665 | 3,053 |
Methyltransferase | 17 | 46 | 2.162144 | 0.030607 | O43148,Q7L592,Q9H7B4,Q99707,Q9UET6,Q9NRG4,Q96L73,Q6P2P2,Q9BV86,Q13395,O96028,P22061,Q96P11,O60725,Q8N6R0,Q86X55,P21964 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 636,364,691,589,106,239,495,382,48,49,682,457,613,26,610,350,225 | 869,2882,636,1248,872,26,682,225,457,2183,1631,2817,882,851,49,2929,1638,727,382,1640,1051,364,2111,1230,1990,350,1393,1569,610,1810,1770,2034,495,613,589,1057,1208,48,691,1405,1696,1000,239,1651,106,2210 | 0.3781239970118069,-1.278570283055428,0.5940047747374697,0.09194865127890278,0.3781239970118069,3.0918170578907094,0.5511109868815428,1.3441122067215945,0.8275069838030819,-0.47808490468523474,-0.1554820011028002,-1.1034851164802537,0.3781239970118069,0.3998733474246863,2.535607321248751,-1.4312098217663123,-0.1554820011028002,0.5080778484189623,0.9740581370180955,-0.1554820011028002,0.24684817531299486,1.0156498223536288,-0.4314392761759522,0.11419540272429664,-0.36182891654219795,1.036399894714161,0.0025570802874198603,-0.11011503607208795,0.6367609840083165,-0.24674132056841452,-0.22385997559133067,-0.38498514034941356,0.7853489674913086,0.6367609840083165,0.6580880397299336,0.24684817531299486,0.13640227399311802,2.554434984977978,0.5511109868815428,0.0025570802874198603,-0.17823065580578884,0.2907569811734416,1.3034573165650833,-0.1554820011028002,1.9216692731632823,-0.47808490468523474 | 3,053 |
Nuclear receptors metapathway | 13 | 49 | 2.160814 | 0.03071 | Q15257,P23786,Q14145,P09601,P30043,Q06520,Q13501,P11802,Q15067,P00390,O15217,P40763,P08183 | Processes and pathways | WikiPathways | msigdb_wp | 380,130,42,11,167,14,47,357,338,85,86,405,92 | 1476,400,86,85,2008,2011,1943,92,1975,2785,11,2383,2418,502,357,1553,3046,906,2646,130,2361,1667,1835,167,2060,405,2744,983,2136,2550,14,800,2189,1489,1920,47,1603,42,2777,1283,2432,338,629,380,701,2399,2403,1237,2526 | -0.06491969310546976,0.9323432018484419,2.0966674446159113,2.115995366359213,-0.38498514034941356,-0.38498514034941356,-0.3387194179434577,2.0191249668757036,-0.36182891654219795,-1.0540235788334475,3.9307710524391237,-0.6192028971632252,-0.6428991995691181,0.7642212825740413,1.0156498223536288,-0.11011503607208795,-4.199109660747921,0.3563379335731602,-0.8585443854221945,1.7447281172585196,-0.5955577777283037,-0.17823065580578884,-0.2696675832309689,1.5457402004209786,-0.4081884661759546,0.9323432018484419,-0.9802821143207153,0.2907569811734416,-0.45473795795566646,-0.7382051822514453,3.666989822854212,0.443262882592413,-0.47808490468523474,-0.06491969310546976,-0.3156562729795899,2.573242040306225,-0.13277690412101875,2.6482659504229598,-1.0293835579205086,0.06966173419709126,-0.6428991995691181,1.0571196890420318,0.6153999674831028,0.9740581370180955,0.5296119487856337,-0.6192028971632252,-0.6192028971632252,0.11419540272429664,-0.7142996591987354 | 3,053 |
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