term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Proteasome component (PCI) domain [IPR000717]
10
17
2.941426
0.003267
O00231,Q99627,Q9UBW8,Q15008,Q9Y262,Q9UNM6,Q7L2H7,Q13098,Q9UBQ5,P60228
Sequence
InterPro Domain
interpro_domain
305,99,38,408,211,416,21,238,324,315
305,928,497,827,315,1269,238,906,408,21,99,918,324,38,416,417,211
0.7850662756234686,0.2031110399977868,0.5457559728599943,0.3060033706040031,0.7850662756234686,-0.07170257917698318,0.9216248161647249,0.23741811556684678,0.648370384959647,3.494172256495323,1.5345340316692926,0.23741811556684678,0.7850662756234686,2.517022513907188,0.648370384959647,0.648370384959647,0.9898537517248991
2,448
Hedgehog off state
32
48
2.918565
0.003516
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,Q9BUF5,P25788,P68371,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q96J02,P25786,P10644,P25789,P17612,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,276,640,406,514,701,40,166,42,164,321,56,305,67,208,332,330,216,588,354,596,653,655
305,928,884,496,497,252,330,1577,588,505,67,332,164,640,216,821,42,16,135,859,946,827,1455,128,9,1052,514,166,40,596,354,688,1185,653,406,1029,903,655,952,408,701,208,56,321,276,1924,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.7509053294850906,-0.3471813243224761,0.4773013586496177,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,-0.24379596346019208,1.262444229636026,4.73422667524134,0.10013110654278463,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.648370384959647,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.2031110399977868,0.648370384959647,0.4088101174779366,0.9898537517248991,2.1111705564621013,0.7850662756234686,0.8533624771761494,-0.6233729186226958,-0.20935598039970602,0.648370384959647
2,448
Fc epsilon receptor fceri signaling
31
44
2.903732
0.003687
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,P61088,O00231,P20618,P27361,P25786,Q13177,P25789,P62191,P61289,P62993,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,432,305,67,311,332,601,216,354,596,651,653,655
305,928,884,496,497,252,505,67,332,164,640,216,311,821,42,16,135,976,859,946,827,128,9,514,166,40,432,596,354,688,1185,651,653,1029,601,903,655,408,1673,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7850662756234686,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.16879423156617618,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.6141744951918664,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.44306035048595727,0.1344676131809928,0.4773013586496177,0.23741811556684678,0.44306035048595727,0.648370384959647,-0.4161603820269248,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Proteasome B-type subunit [IPR023333]
6
7
2.902259
0.003705
P20618,P49720,P49721,P28070,P28072,Q99436
Sequence
InterPro Family
interpro_family
67,128,9,42,16,56
67,42,16,135,128,9,56
1.8061474551769805,2.4156471929658223,4.131824187305753,1.2283983252262376,1.262444229636026,4.73422667524134,2.1111705564621013
2,448
Proteasome core complex beta subunit complex
6
7
2.902259
0.003705
P20618,P49720,P49721,P28070,P28072,Q99436
Localization
GO Cellular component
msigdb_gocc
67,128,9,42,16,56
67,42,16,135,128,9,56
1.8061474551769805,2.4156471929658223,4.131824187305753,1.2283983252262376,1.262444229636026,4.73422667524134,2.1111705564621013
2,448
Uch proteinases
19
44
2.900981
0.00372
P49720,Q8NB78,O75832,Q15008,P49721,P28074,P28072,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191,Q9Y5K5
Processes and pathways
Reactome Pathways
msigdb_reactome
128,5,252,408,9,135,16,40,166,42,164,321,56,305,67,332,216,354,133
305,928,884,496,710,497,252,2150,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,1310,514,166,40,596,354,688,1185,1029,903,408,657,5,701,56,321,1431,416,1482,1361,133
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.37455059026533083,0.5457559728599943,0.8874978505064713,-0.8656683146306153,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,-0.10610013099584205,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.44306035048595727,5.801462288194559,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647,-0.24379596346019208,-0.14050815550820908,1.262444229636026
2,448
Alzheimers disease and mirna effects
21
75
2.900593
0.003725
P49720,Q15008,P49721,Q9UNM6,P28074,P28072,Q9BUF5,Q00535,P60900,P55036,P28070,P25787,P33176,P07437,Q99460,Q99436,P20618,P27361,P25786,P25789,P62191
Processes and pathways
WikiPathways
msigdb_wp
128,408,9,416,135,16,276,157,40,166,42,164,291,288,321,56,67,311,332,216,354
928,884,930,496,497,1173,582,2371,1698,544,940,288,503,1337,1902,1215,2176,1016,505,820,1409,67,1262,332,164,640,216,311,821,42,16,135,976,1981,291,1863,859,1222,946,1494,827,1455,644,128,9,1052,514,166,40,354,688,1185,1271,406,157,1101,951,1102,903,737,952,408,657,1677,2220,1472,56,321,615,2237,276,1924,2263,416,2004
0.2031110399977868,0.23741811556684678,0.2031110399977868,0.5457559728599943,0.5457559728599943,-0.0029385446148907503,0.4773013586496177,-1.4566422868933564,-0.45066685732428435,0.5115332103198423,0.2031110399977868,0.8192186384010108,0.5457559728599943,-0.14050815550820908,-0.6233729186226958,-0.03731541244345559,-0.9003323161906817,0.1344676131809928,0.5457559728599943,0.3060033706040031,-0.20935598039970602,1.8061474551769805,-0.07170257917698318,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7850662756234686,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.16879423156617618,-0.6925384579151646,0.8192186384010108,-0.5888081853381918,0.271715534183546,-0.03731541244345559,0.2031110399977868,-0.278246784654138,0.3060033706040031,-0.24379596346019208,0.44306035048595727,1.262444229636026,4.73422667524134,0.10013110654278463,0.5457559728599943,1.1262131892268594,2.48323710882666,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-0.07170257917698318,0.648370384959647,1.1602828560626173,0.06578463211521306,0.2031110399977868,0.06578463211521306,0.23741811556684678,0.37455059026533083,0.2031110399977868,0.648370384959647,0.44306035048595727,-0.4161603820269248,-0.9696990541422212,-0.24379596346019208,2.1111705564621013,0.7850662756234686,0.4773013586496177,-1.0044015886837547,0.8533624771761494,-0.6233729186226958,-1.0391167407626585,0.648370384959647,-0.6925384579151646
2,448
Ub specific processing proteases
21
64
2.885608
0.003907
P49720,P45974,Q15008,O75832,Q96K76,P49721,P28074,P28072,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,Q96FW1,Q8TEY7,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,255,408,252,143,9,135,16,40,166,42,164,321,56,305,67,332,216,98,357,354
305,928,884,496,497,1046,252,1820,2270,1215,505,67,1262,332,164,640,216,821,42,16,135,859,946,1494,255,827,128,9,514,828,166,40,596,354,688,1185,1029,903,2255,1152,408,1155,1673,657,659,2101,357,701,1114,957,1886,98,143,56,321,1038,662,1431,416,1482,2004,1774,2087,1361
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.10013110654278463,0.8874978505064713,-0.554255323491472,-1.073844393574436,-0.03731541244345559,0.5457559728599943,1.8061474551769805,-0.07170257917698318,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,-0.278246784654138,0.8874978505064713,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,0.3060033706040031,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,-1.0391167407626585,0.03142810909569467,0.648370384959647,0.03142810909569467,-0.4161603820269248,0.44306035048595727,0.44306035048595727,-0.7963787260487372,0.7167357398101687,0.4088101174779366,0.06578463211521306,0.2031110399977868,-0.5888081853381918,1.5345340316692926,1.2283983252262376,2.1111705564621013,0.7850662756234686,0.1344676131809928,0.44306035048595727,-0.20935598039970602,0.648370384959647,-0.24379596346019208,-0.6925384579151646,-0.48518476837761204,-0.7617528802884621,-0.14050815550820908
2,448
Tcr signaling
29
41
2.885092
0.003913
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,P61088,O00231,P20618,P25786,Q13177,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,432,305,67,332,601,216,354,596,653,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,1140,946,827,128,9,514,166,40,432,596,354,688,1185,653,1029,601,903,655,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.03142810909569467,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.6141744951918664,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.4773013586496177,0.23741811556684678,0.44306035048595727,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Tnfr2 non canonical nf kb pathway
29
40
2.876404
0.004022
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,Q8TBC4,P20618,P61081,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,66,67,472,332,216,354,596,653,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,472,596,354,688,1185,653,1029,903,655,408,66,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.5799697126669984,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.648370384959647,1.8739790092252244,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Dectin 1 mediated noncanonical nf kb signaling
29
40
2.876404
0.004022
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,Q8TBC4,P20618,P61081,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,66,67,472,332,216,354,596,653,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,472,596,354,688,1185,653,1029,903,655,408,66,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.5799697126669984,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.648370384959647,1.8739790092252244,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Clec7a dectin 1 signaling
30
42
2.874586
0.004046
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,P61088,O00231,Q8TBC4,P20618,P61081,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,432,305,66,67,472,332,216,354,596,653,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,472,432,596,354,688,1185,653,1029,903,655,408,1673,66,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.5799697126669984,0.6141744951918664,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.648370384959647,-0.4161603820269248,1.8739790092252244,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Cyclin a cdk2 associated events at s phase entry
29
40
2.870385
0.0041
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,P06400,Q99460,Q99436,O00231,P20618,P11802,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,287,321,56,305,67,195,332,216,354,596,653,655
305,928,884,496,497,252,287,195,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,653,1029,903,655,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.8192186384010108,1.0239558333863061,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Degradation of gli1 by the proteasome
29
40
2.86658
0.004149
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q96J02,P25786,P25789,P17612,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,67,208,332,216,588,354,596,653,655
305,928,884,496,497,252,588,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,653,1029,903,655,408,701,208,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.4773013586496177,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.648370384959647,0.4088101174779366,0.9898537517248991,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Abc transporter disorders
22
40
2.851067
0.004357
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q9BUN8,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,197,332,216,354
305,928,884,496,497,252,1533,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,1225,40,596,354,688,1185,1029,903,408,701,56,321,197,1359,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,-0.3127085392865689,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,-0.03731541244345559,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,1.0239558333863061,-0.14050815550820908,-0.20935598039970602,0.648370384959647
2,448
Defective cftr causes cystic fibrosis
22
40
2.851067
0.004357
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q9BUN8,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,197,332,216,354
305,928,884,496,497,252,1533,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,1225,40,596,354,688,1185,1029,903,408,701,56,321,197,1359,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,-0.3127085392865689,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,-0.03731541244345559,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,1.0239558333863061,-0.14050815550820908,-0.20935598039970602,0.648370384959647
2,448
Regulation of hmox1 expression and activity
28
43
2.842648
0.004474
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P09601,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,67,332,216,586,354,596,653,655
305,928,884,496,497,252,586,505,1409,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,653,1271,1029,903,655,1347,408,1353,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.4773013586496177,0.5457559728599943,-0.20935598039970602,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,-0.07170257917698318,0.1344676131809928,0.23741811556684678,0.44306035048595727,-0.14050815550820908,0.648370384959647,-0.14050815550820908,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Apc c mediated degradation of cell cycle proteins
33
51
2.837867
0.004542
P49720,P14635,O75832,Q16763,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,P06400,Q99460,Q99436,O00231,P20618,Q9UJX4,P25786,P25789,P06493,P62191,O60566,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,253,252,409,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,287,321,56,305,67,488,332,216,583,354,100,596,653,655
305,928,884,496,2386,497,1045,100,252,287,583,253,505,67,332,164,640,216,821,42,16,135,1177,859,946,827,128,9,514,1586,166,40,596,354,688,1185,653,1029,903,655,408,409,701,56,321,1927,1122,1569,488,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,-1.526392025421465,0.5457559728599943,0.10013110654278463,1.5005493340872977,0.8874978505064713,0.8192186384010108,0.4773013586496177,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,-0.0029385446148907503,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,-0.3471813243224761,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.648370384959647,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.6233729186226958,0.06578463211521306,-0.3127085392865689,0.5799697126669984,-0.20935598039970602,0.648370384959647
2,448
Scf skp2 mediated degradation of p27 p21
28
39
2.833072
0.00461
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P11802,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,67,195,332,216,354,596,653,655
305,928,884,496,497,252,195,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,653,1029,903,655,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,1.0239558333863061,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Negative regulation of notch4 signaling
28
39
2.828031
0.004684
P49720,P63104,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,518,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,67,332,216,354,596,653,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,518,653,1029,903,655,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.5457559728599943,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Signaling by the b cell receptor bcr
28
39
2.826931
0.0047
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191,P61289,P62993,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,67,332,216,354,596,651,653,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,651,653,1029,903,655,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Regulation of mrna stability by proteins that bind au rich elements
27
58
2.82323
0.004754
P49720,P63104,Q04637,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q9Y2L1,P25786,P25789,P62191,Q01105,Q92945,Q92973
Processes and pathways
Reactome Pathways
msigdb_reactome
128,518,379,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,212,332,216,354,115,531,532
305,928,884,496,968,497,252,1860,817,772,505,67,332,164,640,216,821,42,16,135,684,1581,859,946,827,128,9,514,166,40,596,354,688,1185,518,115,379,2183,1029,903,1380,1549,408,1318,1798,2277,1277,701,531,532,1993,56,321,1515,1000,1431,416,212
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.16879423156617618,0.5457559728599943,0.8874978505064713,-0.5888081853381918,0.3060033706040031,0.3402816984562314,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.4088101174779366,-0.3471813243224761,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.5457559728599943,1.3985501409397767,0.6825574455888234,-0.9003323161906817,0.1344676131809928,0.23741811556684678,-0.17492674178561746,-0.3127085392865689,0.648370384959647,-0.10610013099584205,-0.5197142211354513,-1.073844393574436,-0.07170257917698318,0.4088101174779366,0.5457559728599943,0.5457559728599943,-0.6925384579151646,2.1111705564621013,0.7850662756234686,-0.278246784654138,0.16879423156617618,-0.20935598039970602,0.648370384959647,0.9898537517248991
2,448
Hedgehog ligand biogenesis
21
39
2.816048
0.004862
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,1405,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,1225,40,596,354,688,1185,1029,903,408,701,56,321,1359,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,-0.20935598039970602,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,-0.03731541244345559,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.14050815550820908,-0.20935598039970602,0.648370384959647
2,448
Hedgehog on state
22
40
2.812632
0.004914
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q96J02,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,208,332,216,354
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,1455,128,9,514,166,40,596,354,688,1185,1029,903,1347,408,794,701,208,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,-0.24379596346019208,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,-0.14050815550820908,0.648370384959647,0.3402816984562314,0.4088101174779366,0.9898537517248991,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Degradation of axin
21
36
2.809661
0.004959
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Cross presentation of soluble exogenous antigens endosomes
21
36
2.809661
0.004959
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Mapk6 mapk4 signaling
30
46
2.80956
0.004961
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q16181,P25786,Q13177,P25789,P06493,P17612,P62191,P61289,P25685
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,67,605,332,601,216,583,588,354,596,233
305,928,884,496,968,497,252,1860,583,588,505,67,233,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,1226,596,354,688,1185,1029,601,903,408,605,701,56,321,758,805,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.16879423156617618,0.5457559728599943,0.8874978505064713,-0.5888081853381918,0.4773013586496177,0.4773013586496177,0.5457559728599943,1.8061474551769805,0.9216248161647249,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,-0.03731541244345559,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.4773013586496177,0.23741811556684678,0.648370384959647,0.4773013586496177,0.4088101174779366,2.1111705564621013,0.7850662756234686,0.37455059026533083,0.3402816984562314,-0.20935598039970602,0.648370384959647
2,448
Regulation of ras by gaps
21
37
2.808643
0.004975
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,1347,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,-0.14050815550820908,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Degradation of dvl
21
37
2.808643
0.004975
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,1347,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,-0.14050815550820908,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Regulation of runx2 expression and activity
27
42
2.807214
0.004997
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,67,332,216,354,596,653,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,1141,946,827,128,9,1052,514,166,40,596,354,688,1185,653,1029,903,655,904,408,701,56,321,1431,1002,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.03142810909569467,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.10013110654278463,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.16879423156617618,0.648370384959647
2,448
Downstream signaling events of b cell receptor bcr
27
38
2.794872
0.005192
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,67,332,216,354,596,653,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,653,1029,903,655,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Regulation of runx3 expression and activity
21
37
2.792737
0.005226
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,904,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Fceri mediated nf kb activation
28
40
2.78349
0.005378
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,P61088,O00231,P20618,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,432,305,67,332,216,354,596,653,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,432,596,354,688,1185,653,1029,903,655,408,1673,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.6141744951918664,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.648370384959647,-0.4161603820269248,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Peptidase complex
22
52
2.779107
0.005451
P49720,O75832,Q15008,P49721,P28074,P28072,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q15386,P25786,O43396,P25789,P62191,P54727,Q5VYK3,Q9Y5K5
Localization
GO Cellular component
msigdb_gocc
128,252,408,9,135,16,40,166,42,164,321,56,305,67,338,332,92,216,354,236,261,133
305,928,884,496,497,92,252,1860,1016,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,828,236,166,1225,40,1543,596,354,688,1185,2158,1029,903,1796,408,338,657,261,701,1074,56,321,1431,416,2087,2298,133
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,1.5685112886631114,0.8874978505064713,-0.5888081853381918,0.1344676131809928,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,0.3060033706040031,0.9216248161647249,1.1262131892268594,-0.03731541244345559,2.48323710882666,-0.3127085392865689,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-0.8656683146306153,0.1344676131809928,0.23741811556684678,-0.5197142211354513,0.648370384959647,0.7509053294850906,0.44306035048595727,0.8874978505064713,0.4088101174779366,0.10013110654278463,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647,-0.7617528802884621,-1.1085844324982728,1.262444229636026
2,448
The role of gtse1 in g2 m progression after g2 checkpoint
32
47
2.773254
0.00555
Q15691,P49720,P14635,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,Q9BUF5,P25788,P68371,P51665,Q92530,P60900,P55036,P28070,P25787,P07900,Q99460,Q99436,O00231,P20618,P25786,P25789,P06493,P08238,P62191,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
130,128,253,252,408,9,497,416,135,16,496,505,276,640,406,514,701,40,166,42,164,546,321,56,305,67,332,216,583,585,354,596
305,928,884,496,497,252,2270,583,546,585,253,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,1586,166,40,596,354,688,1185,406,1029,903,952,408,130,701,56,321,276,1924,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,-1.073844393574436,0.4773013586496177,0.5115332103198423,0.4773013586496177,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,-0.3471813243224761,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.648370384959647,0.1344676131809928,0.23741811556684678,0.2031110399977868,0.648370384959647,1.262444229636026,0.4088101174779366,2.1111705564621013,0.7850662756234686,0.8533624771761494,-0.6233729186226958,-0.20935598039970602,0.648370384959647
2,448
Proteasome
20
35
2.767743
0.005645
P49720,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
KEGG Pathways
msigdb_kegg
128,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Metabolism of polyamines
26
37
2.764697
0.005698
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P19623,P25789,P62191,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,67,332,589,216,354,596
305,928,884,496,497,252,505,589,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,0.4773013586496177,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Switching of origins to a post replicative state
28
51
2.76398
0.00571
P49720,O75832,Q16763,P49721,Q15008,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P33991,P49736,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P33993,Q9UJX4,P25786,P25789,P62191,P25205,Q14566
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,409,9,408,497,416,135,16,496,505,395,513,40,166,42,164,321,56,305,67,313,488,332,216,354,465,523
305,928,884,496,497,2427,252,505,67,465,332,164,640,216,821,42,16,135,1177,395,723,313,859,946,827,128,9,513,514,166,40,596,354,688,1185,653,1029,903,655,523,408,409,701,56,321,1927,1122,1569,488,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-2.0508795111775275,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.5799697126669984,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,-0.0029385446148907503,0.648370384959647,0.37455059026533083,0.7850662756234686,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.5457559728599943,0.648370384959647,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.6233729186226958,0.06578463211521306,-0.3127085392865689,0.5799697126669984,-0.20935598039970602,0.648370384959647
2,448
Disorders of transmembrane transporters
19
70
2.758192
0.005812
P49720,O75832,Q15008,P49721,P28074,P28072,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q9BUN8,P25786,P25789,P62191,O00400
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,135,16,40,166,42,164,321,56,305,67,197,332,216,354,111
305,928,111,884,496,497,1618,252,1533,501,974,505,2122,67,332,164,640,216,821,42,16,135,779,1581,859,946,827,128,9,1223,1747,514,1791,595,166,1225,1056,40,596,354,688,1185,2182,1029,1548,903,408,1278,2205,1192,997,1112,2029,1962,1388,701,1561,2383,56,321,1286,2138,197,1248,1769,1729,1359,1935,1431,416
0.7850662756234686,0.2031110399977868,1.4325574349613057,0.23741811556684678,0.5457559728599943,0.5457559728599943,-0.3816652384302993,0.8874978505064713,-0.3127085392865689,0.5457559728599943,0.16879423156617618,0.5457559728599943,-0.8310171614704213,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.3402816984562314,-0.3471813243224761,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,-0.03731541244345559,-0.48518476837761204,0.5457559728599943,-0.5197142211354513,0.4773013586496177,1.1262131892268594,-0.03731541244345559,0.10013110654278463,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-0.9003323161906817,0.1344676131809928,-0.3127085392865689,0.23741811556684678,0.648370384959647,-0.07170257917698318,-0.9350092561896616,-0.0029385446148907503,0.16879423156617618,0.06578463211521306,-0.7271394986212955,-0.6579496374044261,-0.17492674178561746,0.4088101174779366,-0.3127085392865689,-1.4915115757371213,2.1111705564621013,0.7850662756234686,-0.07170257917698318,-0.8310171614704213,1.0239558333863061,-0.03731541244345559,-0.48518476837761204,-0.45066685732428435,-0.14050815550820908,-0.6233729186226958,-0.20935598039970602,0.648370384959647
2,448
Signaling by interleukins
48
99
2.754446
0.005879
P49720,P63104,O75832,Q13126,P49721,Q15008,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P30154,P25788,Q00169,P51665,P04083,Q14738,Q92530,P60900,P55036,P28070,P30153,P25787,P07900,P09429,Q99436,P26038,Q99460,P61088,P14174,P51452,O00231,P20618,P27361,Q16658,Q99439,P25786,P17987,Q13177,P25789,P09601,P17612,P62191,P61289,P62993,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,518,252,8,9,408,497,416,135,16,496,505,511,640,147,514,153,694,701,40,166,42,165,164,546,547,56,549,321,432,63,64,305,67,311,606,75,332,331,601,216,586,588,354,596,651,653,655
1526,305,928,884,496,811,497,252,153,2287,2270,2371,770,1944,1405,1822,546,972,547,586,1304,817,2119,63,1824,588,505,331,67,1535,1411,719,332,164,640,216,549,311,2155,821,42,16,135,976,165,511,859,980,2180,685,981,1141,946,1266,827,128,9,64,1705,514,983,1951,1224,1339,166,40,1226,432,596,354,688,1185,651,518,653,901,147,1101,1149,1029,8,601,903,1873,655,694,408,2234,1673,2277,606,2206,701,56,75,321,1291,1431,416
-0.3127085392865689,0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.3060033706040031,0.5457559728599943,0.8874978505064713,1.1602828560626173,-1.1085844324982728,-1.073844393574436,-1.4566422868933564,0.3402816984562314,-0.6579496374044261,-0.20935598039970602,-0.554255323491472,0.5115332103198423,0.16879423156617618,0.5115332103198423,0.4773013586496177,-0.10610013099584205,0.3060033706040031,-0.8310171614704213,1.941782504586402,-0.554255323491472,0.4773013586496177,0.5457559728599943,0.7509053294850906,1.8061474551769805,-0.3127085392865689,-0.20935598039970602,0.37455059026533083,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.5115332103198423,0.7850662756234686,-0.8656683146306153,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.16879423156617618,1.1262131892268594,0.5457559728599943,0.271715534183546,0.16879423156617618,-0.9003323161906817,0.4088101174779366,0.16879423156617618,0.03142810909569467,0.2031110399977868,-0.07170257917698318,0.3060033706040031,1.262444229636026,4.73422667524134,1.9078842441946644,-0.45066685732428435,0.5457559728599943,0.16879423156617618,-0.6579496374044261,-0.03731541244345559,-0.14050815550820908,1.1262131892268594,2.48323710882666,-0.03731541244345559,0.6141744951918664,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.5457559728599943,0.44306035048595727,0.23741811556684678,1.1943445509410995,0.06578463211521306,0.03142810909569467,0.1344676131809928,4.801064161879333,0.4773013586496177,0.23741811556684678,-0.5888081853381918,0.44306035048595727,0.4088101174779366,0.648370384959647,-1.0044015886837547,-0.4161603820269248,-1.073844393574436,0.4773013586496177,-0.9350092561896616,0.4088101174779366,2.1111705564621013,1.704346800376886,0.7850662756234686,-0.07170257917698318,-0.20935598039970602,0.648370384959647
2,448
Cellular response to hypoxia
26
38
2.733198
0.006272
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,Q13617,P25789,P62191,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,67,332,602,216,354,596
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,602,408,1553,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.4773013586496177,0.648370384959647,-0.3127085392865689,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Asymmetric localization of pcp proteins
21
37
2.72999
0.006334
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,1914,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,-0.6233729186226958,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Dna replication pre initiation
30
54
2.709781
0.006733
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P33991,P49736,P49643,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P33993,P25786,P25789,P27694,P62191,P25205,P15927,Q14566,Q07864
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,395,513,400,40,166,42,164,321,56,305,67,313,332,216,348,354,465,347,523,519
305,928,884,496,497,2427,672,252,1305,347,2325,505,67,465,332,164,640,216,348,821,42,16,135,395,723,313,859,946,827,1309,400,128,9,513,514,1338,166,40,596,354,688,1185,2397,1029,519,903,523,1064,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-2.0508795111775275,0.4088101174779366,0.8874978505064713,-0.10610013099584205,0.7167357398101687,-1.2128777512230653,0.5457559728599943,1.8061474551769805,0.5799697126669984,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7167357398101687,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.648370384959647,0.37455059026533083,0.7850662756234686,0.271715534183546,0.2031110399977868,0.3060033706040031,-0.10610013099584205,0.648370384959647,1.262444229636026,4.73422667524134,0.5457559728599943,0.5457559728599943,-0.14050815550820908,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-1.5961860445795646,0.1344676131809928,0.5457559728599943,0.23741811556684678,0.5457559728599943,0.10013110654278463,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Pcp ce pathway
18
47
2.708853
0.006752
P25789,O00231,P20618,P49720,P62191,O75832,Q15008,P49721,P60900,P55036,P28070,P25787,P61586,P28074,P28072,P25786,Q99460,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
216,305,67,128,354,252,408,9,40,166,42,164,46,135,16,332,321,56
305,928,884,496,497,252,934,1697,851,637,1176,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,1542,166,40,596,46,354,688,1185,989,734,1029,903,1914,408,701,1512,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.2031110399977868,-0.45066685732428435,0.271715534183546,0.44306035048595727,-0.0029385446148907503,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,-0.3127085392865689,1.1262131892268594,2.48323710882666,0.4773013586496177,2.348031579016722,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.16879423156617618,0.37455059026533083,0.1344676131809928,0.23741811556684678,-0.6233729186226958,0.648370384959647,0.4088101174779366,-0.278246784654138,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Regulation of pten stability and activity
21
40
2.706946
0.006791
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,2056,505,1409,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1271,1029,903,408,701,56,321,1431,1002,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,-0.7617528802884621,0.5457559728599943,-0.20935598039970602,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-0.07170257917698318,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.16879423156617618,0.648370384959647
2,448
Auf1 hnrnp d0 binds and destabilizes mrna
22
41
2.700946
0.006914
P49720,Q04637,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,379,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,1860,817,772,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,379,1029,903,1549,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,-0.5888081853381918,0.3060033706040031,0.3402816984562314,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.6825574455888234,0.1344676131809928,0.23741811556684678,-0.3127085392865689,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Nucleoside triphosphatase regulator activity
33
56
2.686739
0.007215
Q15436,P50395,O60343,Q9H3U1,P29692,P80303,Q9NWX6,P52565,Q13144,Q02818,Q13576,O00429,P18085,Q8TC07,P55010,P43487,O14786,O43924,P31150,P24534,Q4KMP7,Q92974,Q9Y2L1,P49770,Q9BTW9,Q9P258,O75592,O00410,O95373,Q9NR50,Q9H6Z4,Q13098,Q8N6T3
Functions
GO Molecular function
msigdb_gomf
259,646,630,279,510,26,162,295,561,31,33,669,548,178,55,190,60,187,550,683,607,748,212,314,485,622,88,578,214,105,242,238,262
578,669,60,187,630,88,1402,214,548,855,683,510,550,190,1495,1182,314,1747,646,295,55,2381,26,31,238,561,33,908,1915,991,1106,992,259,607,1350,1194,1240,262,178,745,748,2209,1725,485,1198,279,242,1357,105,162,1520,622,962,1295,212,1081
0.4773013586496177,0.4088101174779366,2.009558259342313,1.058049730923791,0.44306035048595727,1.6024811499433442,-0.20935598039970602,0.9557434311544011,0.5115332103198423,0.271715534183546,0.4088101174779366,0.5457559728599943,0.5115332103198423,1.058049730923791,-0.278246784654138,-0.0029385446148907503,0.7850662756234686,-0.48518476837761204,0.44306035048595727,0.8192186384010108,2.1111705564621013,-1.4915115757371213,2.989368530256347,2.753345068924629,0.9216248161647249,0.5115332103198423,2.6183409124581645,0.23741811556684678,-0.6233729186226958,0.16879423156617618,0.06578463211521306,0.16879423156617618,0.8874978505064713,0.4773013586496177,-0.14050815550820908,-0.0029385446148907503,-0.03731541244345559,0.8874978505064713,1.0921354984116292,0.37455059026533083,0.37455059026533083,-0.9350092561896616,-0.45066685732428435,0.5799697126669984,-0.0029385446148907503,0.8533624771761494,0.9216248161647249,-0.14050815550820908,1.5005493340872977,1.1602828560626173,-0.278246784654138,0.4773013586496177,0.2031110399977868,-0.07170257917698318,0.9898537517248991,0.10013110654278463
2,448
Degradation of beta catenin by the destruction complex
31
47
2.67628
0.007444
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P30154,P25788,P51665,Q14738,Q92530,P60900,P55036,P28070,P25787,P30153,Q99460,Q99436,Q13363,O00231,P20618,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,511,640,514,694,701,40,166,42,164,165,321,56,61,305,67,332,216,354,596,653,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,165,511,1863,859,946,827,1455,128,9,1052,514,166,1707,40,596,354,688,1185,653,1029,903,61,2373,655,694,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.1262131892268594,0.5457559728599943,-0.5888081853381918,0.271715534183546,0.2031110399977868,0.3060033706040031,-0.24379596346019208,1.262444229636026,4.73422667524134,0.10013110654278463,0.5457559728599943,1.1262131892268594,-0.45066685732428435,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,2.009558259342313,-1.4566422868933564,0.44306035048595727,0.4088101174779366,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
24
45
2.661089
0.007789
P49720,O75832,Q16763,P49721,Q15008,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,P06400,Q99460,Q99436,O00231,P20618,Q9UJX4,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,409,9,408,497,416,135,16,496,505,40,166,42,164,287,321,56,305,67,488,332,216,354
305,928,884,496,2386,497,252,287,505,67,332,164,640,216,821,42,16,135,1177,859,946,827,128,9,514,1586,166,40,596,354,688,1185,1029,903,408,409,701,56,321,1927,1122,1569,488,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,-1.526392025421465,0.5457559728599943,0.8874978505064713,0.8192186384010108,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,-0.0029385446148907503,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,-0.3471813243224761,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.6233729186226958,0.06578463211521306,-0.3127085392865689,0.5799697126669984,-0.20935598039970602,0.648370384959647
2,448
Orc1 removal from chromatin
32
45
2.655366
0.007922
P49720,Q15008,O75832,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P33991,P25788,P49736,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P33993,P25786,P25789,P62191,P25205,P61289,Q14566,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,408,252,9,497,416,135,16,496,505,395,640,513,514,701,40,166,42,164,321,56,305,67,313,332,216,354,465,596,523,653,655
305,928,884,496,497,2427,252,505,67,465,332,164,640,216,821,42,16,135,395,723,313,859,946,827,128,9,513,514,166,40,596,354,688,1185,653,1029,903,655,523,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-2.0508795111775275,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.5799697126669984,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.648370384959647,0.37455059026533083,0.7850662756234686,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.5457559728599943,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Beta catenin independent wnt signaling
18
49
2.650105
0.008047
P25789,O00231,P20618,P49720,P62191,O75832,Q15008,P49721,P60900,P55036,P28070,P25787,P61586,P28074,P28072,P25786,Q99460,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
216,305,67,128,354,252,408,9,40,166,42,164,46,135,16,332,321,56
305,928,884,496,497,252,934,1697,851,637,1176,505,67,332,164,640,216,821,42,16,135,1863,859,946,827,128,9,514,1542,166,40,596,46,354,688,1185,989,734,1029,903,1914,408,701,1512,56,321,758,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.2031110399977868,-0.45066685732428435,0.271715534183546,0.44306035048595727,-0.0029385446148907503,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,-0.5888081853381918,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,-0.3127085392865689,1.1262131892268594,2.48323710882666,0.4773013586496177,2.348031579016722,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.16879423156617618,0.37455059026533083,0.1344676131809928,0.23741811556684678,-0.6233729186226958,0.648370384959647,0.4088101174779366,-0.278246784654138,2.1111705564621013,0.7850662756234686,0.37455059026533083,-0.20935598039970602,0.648370384959647
2,448
Stabilization of p53
21
38
2.647877
0.0081
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,936,2270,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.2031110399977868,-1.073844393574436,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
G1 s dna damage checkpoints
21
38
2.647877
0.0081
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,936,2270,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.2031110399977868,-1.073844393574436,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Proteasome degradation
23
41
2.637986
0.00834
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P22314,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191,P04844
Processes and pathways
WikiPathways
msigdb_wp
128,252,408,9,497,416,135,16,496,505,393,40,166,42,164,321,56,305,67,332,216,354,106
305,928,496,497,252,1303,1404,1900,106,2012,2325,505,67,393,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,408,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.5457559728599943,0.5457559728599943,0.8874978505064713,-0.10610013099584205,-0.20935598039970602,-0.6233729186226958,1.4665571505046475,-0.7271394986212955,-1.2128777512230653,0.5457559728599943,1.8061474551769805,0.648370384959647,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Ubl conjugation pathway
49
92
2.623607
0.0087
Q14258,P45974,Q96K76,Q16763,Q86VP6,Q9UBE0,Q5VTR2,Q86WB0,Q7Z6Z7,P22314,Q9Y508,Q93034,Q9ULT8,P68036,Q9Y3C8,Q9Y4B6,A0AVT1,P61088,Q8TBC4,Q9C0C9,P61086,Q5T4S7,Q96J02,Q15386,Q8N806,P61081,Q9HB71,Q9UJX4,Q9Y4X5,Q9UPN9,Q13617,O75592,O94822,Q9NXR7,Q9H4L4,Q13564,Q14139,Q96FW1,Q8TEY7,O94874,Q9UBT2,P54727,Q9NT62,Q13263,Q9H8M7,P63208,Q13616,Q86UV5,Q9Y5K5
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
258,255,143,409,410,281,695,698,697,393,709,570,182,558,448,450,667,432,66,199,335,741,208,338,206,472,82,488,492,625,602,88,89,230,756,737,738,98,357,715,246,236,387,521,385,653,655,659,133
667,847,884,710,767,88,89,715,2195,2056,891,393,1177,945,255,1747,828,236,1225,472,335,432,653,558,521,737,655,602,1347,1379,738,258,1063,1632,1152,1231,1553,338,911,409,1758,741,1235,695,955,697,659,410,698,206,795,66,357,1114,957,1886,570,98,2346,208,143,1196,998,1851,199,1927,756,385,82,1476,387,1686,1932,230,281,246,1122,1569,488,182,1612,1002,625,2086,964,1204,448,450,1361,492,709,133
0.4088101174779366,0.271715534183546,0.23741811556684678,0.37455059026533083,0.3402816984562314,1.6024811499433442,1.6024811499433442,0.37455059026533083,-0.9350092561896616,-0.7617528802884621,0.23741811556684678,0.648370384959647,-0.0029385446148907503,0.2031110399977868,0.8874978505064713,-0.48518476837761204,0.3060033706040031,0.9216248161647249,-0.03731541244345559,0.5799697126669984,0.7509053294850906,0.6141744951918664,0.44306035048595727,0.5115332103198423,0.5457559728599943,0.37455059026533083,0.44306035048595727,0.4773013586496177,-0.14050815550820908,-0.17492674178561746,0.37455059026533083,0.8874978505064713,0.10013110654278463,-0.3816652384302993,0.03142810909569467,-0.03731541244345559,-0.3127085392865689,0.7509053294850906,0.23741811556684678,0.648370384959647,-0.48518476837761204,0.37455059026533083,-0.03731541244345559,0.4088101174779366,0.2031110399977868,0.4088101174779366,0.44306035048595727,0.648370384959647,0.4088101174779366,0.9898537517248991,0.3402816984562314,1.8739790092252244,0.7167357398101687,0.06578463211521306,0.2031110399977868,-0.5888081853381918,0.5115332103198423,1.5345340316692926,-1.2824665524224075,0.9898537517248991,1.2283983252262376,-0.0029385446148907503,0.16879423156617618,-0.554255323491472,1.0239558333863061,-0.6233729186226958,0.37455059026533083,0.6825574455888234,1.6703988622284125,-0.24379596346019208,0.6825574455888234,-0.4161603820269248,-0.6233729186226958,0.9557434311544011,0.8533624771761494,0.9216248161647249,0.06578463211521306,-0.3127085392865689,0.5799697126669984,1.0921354984116292,-0.3471813243224761,0.16879423156617618,0.4773013586496177,-0.7617528802884621,0.2031110399977868,-0.0029385446148907503,0.6141744951918664,0.6141744951918664,-0.14050815550820908,0.5799697126669984,0.4088101174779366,1.262444229636026
2,448
Interleukin 1 family signaling
29
47
2.612273
0.008994
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,P09429,P61088,O00231,P20618,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,547,432,305,67,332,216,354,596,653,655
305,928,884,496,497,252,2371,547,505,67,332,164,640,216,821,42,16,135,859,981,946,827,128,9,514,166,40,432,596,354,688,1185,653,1101,1149,1029,903,1873,655,408,1673,701,56,321,1291,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,-1.4566422868933564,0.5115332103198423,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.16879423156617618,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.6141744951918664,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.06578463211521306,0.03142810909569467,0.1344676131809928,0.23741811556684678,-0.5888081853381918,0.44306035048595727,0.648370384959647,-0.4161603820269248,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.07170257917698318,-0.20935598039970602,0.648370384959647
2,448
Enzyme modulator
41
87
2.597213
0.009398
Q15436,P14635,O14530,O15397,O43242,Q9UNM6,O95163,Q9UNS2,P30086,P52565,Q13576,Q99733,Q9NVA2,P55036,P35237,P61586,Q99460,P43487,Q15257,O14737,P55209,Q92616,Q92599,Q16181,Q9NTK5,Q92688,Q9UHD8,P50570,Q9BTT0,O00410,O95373,O60271,Q9Y2I1,P42566,Q9H6Z4,Q9H223,Q7L576,Q01105,P55060,Q9H4M9,P46379
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
259,253,494,249,497,416,500,417,20,295,33,172,572,166,44,46,321,190,58,306,431,611,196,605,487,207,623,333,362,578,214,213,247,468,242,241,527,115,237,384,377
928,578,669,494,306,249,497,213,2046,1660,2363,500,214,581,2371,1441,1260,2119,253,20,44,468,190,1495,377,1182,827,1747,1790,333,295,166,237,431,1226,46,731,1415,115,1547,903,33,738,1915,991,1796,835,58,259,791,605,1189,913,2413,1235,1634,2343,1841,527,1760,2101,701,196,611,207,798,799,2137,1725,1036,800,321,172,362,1198,241,384,242,961,487,572,623,1296,1429,416,417,247
0.2031110399977868,0.4773013586496177,0.4088101174779366,0.5457559728599943,0.7850662756234686,0.8874978505064713,0.5457559728599943,0.9557434311544011,-0.7617528802884621,-0.4161603820269248,-1.4217842514891532,0.5457559728599943,0.9557434311544011,0.4773013586496177,-1.4566422868933564,-0.24379596346019208,-0.07170257917698318,-0.8310171614704213,0.8874978505064713,3.56138409547358,2.38184261521284,0.5799697126669984,1.058049730923791,-0.278246784654138,0.6825574455888234,-0.0029385446148907503,0.3060033706040031,-0.48518476837761204,-0.5197142211354513,0.7509053294850906,0.8192186384010108,1.1262131892268594,0.9216248161647249,0.6141744951918664,-0.03731541244345559,2.348031579016722,0.37455059026533083,-0.20935598039970602,1.3985501409397767,-0.3127085392865689,0.23741811556684678,2.6183409124581645,0.37455059026533083,-0.6233729186226958,0.16879423156617618,-0.5197142211354513,0.3060033706040031,2.043435831472084,0.8874978505064713,0.3402816984562314,0.4773013586496177,-0.0029385446148907503,0.23741811556684678,-1.8058267924564126,-0.03731541244345559,-0.3816652384302993,-1.2824665524224075,-0.554255323491472,0.5457559728599943,-0.48518476837761204,-0.7963787260487372,0.4088101174779366,1.0239558333863061,0.4773013586496177,0.9898537517248991,0.3402816984562314,0.3402816984562314,-0.8310171614704213,-0.45066685732428435,0.1344676131809928,0.3402816984562314,0.7850662756234686,1.1262131892268594,0.7167357398101687,-0.0029385446148907503,0.9216248161647249,0.6825574455888234,0.9216248161647249,0.2031110399977868,0.5799697126669984,0.5115332103198423,0.4773013586496177,-0.07170257917698318,-0.20935598039970602,0.648370384959647,0.648370384959647,0.9216248161647249
2,448
Interleukin 1 signaling
29
45
2.577823
0.009942
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,P09429,P61088,O00231,P20618,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,547,432,305,67,332,216,354,596,653,655
305,928,884,496,497,252,2371,547,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,432,596,354,688,1185,653,1101,1029,903,1873,655,408,1673,701,56,321,1291,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,-1.4566422868933564,0.5115332103198423,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.6141744951918664,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.06578463211521306,0.1344676131809928,0.23741811556684678,-0.5888081853381918,0.44306035048595727,0.648370384959647,-0.4161603820269248,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.07170257917698318,-0.20935598039970602,0.648370384959647
2,448
Abc family proteins mediated transport
28
46
2.567964
0.01023
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,P05198,O00231,P20618,Q8NE71,Q9BUN8,P25786,P25789,P62191,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,544,305,67,610,197,332,216,354,596
305,928,884,496,497,2330,252,1533,544,1784,505,774,67,332,164,640,216,821,42,16,135,1446,859,946,827,128,9,514,166,1225,40,596,354,688,1185,1029,903,408,610,701,56,321,197,1359,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-1.2476662299708938,0.8874978505064713,-0.3127085392865689,0.5115332103198423,-0.5197142211354513,0.5457559728599943,0.3402816984562314,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,-0.24379596346019208,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,-0.03731541244345559,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4773013586496177,0.4088101174779366,2.1111705564621013,0.7850662756234686,1.0239558333863061,-0.14050815550820908,-0.20935598039970602,0.648370384959647
2,448
Cdt1 association with the cdc6 orc origin complex
21
37
2.505943
0.012213
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,2427,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,1029,903,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-2.0508795111775275,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
SLC superfamily of solute carriers
9
33
2.49507
0.012593
Q9H2D1,Q70HW3,O00400,Q5T1Q4,P41440,O43772,Q8IXU6,Q6N075,O43808
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
47,17,111,19,54,23,24,27,62
111,23,62,814,1696,134,1698,501,1337,1902,54,1829,595,1662,1590,1871,1715,19,27,1877,2205,17,24,1680,1116,2261,2433,47,1394,1293,1689,1523,1486
1.4325574349613057,3.3933132177188323,1.9756738299362582,0.3060033706040031,-0.45066685732428435,1.2283983252262376,-0.45066685732428435,0.5457559728599943,-0.14050815550820908,-0.6233729186226958,2.1111705564621013,-0.554255323491472,0.4773013586496177,-0.4161603820269248,-0.3471813243224761,-0.5888081853381918,-0.45066685732428435,3.6285741491329415,2.8882515754010067,-0.5888081853381918,-0.9350092561896616,3.9642043108096305,3.359682429333155,-0.4161603820269248,0.06578463211521306,-1.0391167407626585,-2.1911283167810094,2.348031579016722,-0.17492674178561746,-0.07170257917698318,-0.4161603820269248,-0.278246784654138,-0.24379596346019208
2,448
Runx1 regulates transcription of genes involved in differentiation of hscs
22
41
2.470112
0.013507
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q96J02,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,208,332,216,354
305,928,884,496,497,252,2325,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,2397,1272,1029,903,904,408,701,208,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,-1.2128777512230653,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-1.5961860445795646,-0.07170257917698318,0.1344676131809928,0.23741811556684678,0.23741811556684678,0.648370384959647,0.4088101174779366,0.9898537517248991,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Signaling by notch4
28
42
2.469048
0.013547
P49720,P63104,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,518,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,305,67,332,216,354,596,653,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,596,354,688,1185,518,653,1029,2318,903,1756,655,408,701,2220,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.5457559728599943,0.44306035048595727,0.1344676131809928,-1.1781012207532906,0.23741811556684678,-0.48518476837761204,0.44306035048595727,0.648370384959647,0.4088101174779366,-0.9696990541422212,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Apoptosis
36
79
2.434177
0.014926
P49720,P63104,O75832,Q15008,P49721,P61981,O43242,Q9UNM6,Q04917,P28074,P28072,O14818,P17980,P25788,P51665,P49327,Q13464,Q92530,P60900,P55036,P28070,P25787,O00429,P62195,P09429,Q99436,Q99460,O00231,P20618,P27361,P25786,P49354,Q13177,P25789,P62191,P61289
Processes and pathways
Reactome Pathways
msigdb_reactome
128,518,252,408,9,405,497,416,136,135,16,496,505,640,514,644,563,701,40,166,42,164,669,688,547,56,321,305,67,311,332,90,601,216,354,596
305,928,967,669,884,496,497,2046,252,1576,2270,2152,972,547,2053,2392,1408,2246,505,67,1535,332,164,640,216,858,311,821,42,16,135,976,1219,684,1863,1180,859,981,946,827,644,90,128,9,2302,514,1338,166,40,596,405,354,688,730,1185,518,2381,136,1029,2131,1668,1030,601,903,563,1151,1712,1064,408,1419,701,56,321,1038,1772,763,1895,1431,416
0.7850662756234686,0.2031110399977868,0.16879423156617618,0.4088101174779366,0.23741811556684678,0.5457559728599943,0.5457559728599943,-0.7617528802884621,0.8874978505064713,-0.3471813243224761,-1.073844393574436,-0.8656683146306153,0.16879423156617618,0.5115332103198423,-0.7617528802884621,-1.561283544887797,-0.20935598039970602,-1.0391167407626585,0.5457559728599943,1.8061474551769805,-0.3127085392865689,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.271715534183546,0.7850662756234686,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.16879423156617618,-0.03731541244345559,0.4088101174779366,-0.5888081853381918,-0.0029385446148907503,0.271715534183546,0.16879423156617618,0.2031110399977868,0.3060033706040031,0.44306035048595727,1.6024811499433442,1.262444229636026,4.73422667524134,-1.1433367450359972,0.5457559728599943,-0.14050815550820908,1.1262131892268594,2.48323710882666,0.4773013586496177,0.648370384959647,0.7167357398101687,0.4088101174779366,0.37455059026533083,-0.0029385446148907503,0.5457559728599943,-1.4915115757371213,1.2283983252262376,0.1344676131809928,-0.8310171614704213,-0.4161603820269248,0.1344676131809928,0.4773013586496177,0.23741811556684678,0.5115332103198423,0.03142810909569467,-0.45066685732428435,0.10013110654278463,0.648370384959647,-0.20935598039970602,0.4088101174779366,2.1111705564621013,0.7850662756234686,0.1344676131809928,-0.48518476837761204,0.37455059026533083,-0.5888081853381918,-0.20935598039970602,0.648370384959647
2,448
Translation initiation factor
12
20
2.428568
0.015159
P55884,P23588,Q04637,O75153,O15371,Q9Y262,P06730,P55010,O75822,P05198,P78344,P60228
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
402,426,379,10,628,211,545,55,420,544,654,315
628,629,10,420,544,545,774,426,55,402,1663,315,1147,654,379,868,906,1153,1297,211
0.44306035048595727,0.44306035048595727,4.6673703695070285,0.6141744951918664,0.5115332103198423,0.5115332103198423,0.3402816984562314,0.6141744951918664,2.1111705564621013,0.648370384959647,-0.4161603820269248,0.7850662756234686,0.03142810909569467,0.44306035048595727,0.6825574455888234,0.271715534183546,0.23741811556684678,0.03142810909569467,-0.07170257917698318,0.9898537517248991
2,448
GTPase activation
8
16
2.420736
0.015489
Q4KMP7,P50395,Q9BTW9,P43487,Q8TC07,P52565,Q8N6T3,P31150
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
607,646,485,190,178,295,262,550
630,550,190,1495,646,295,991,1106,607,1194,1240,262,178,485,1198,1081
0.44306035048595727,0.5115332103198423,1.058049730923791,-0.278246784654138,0.44306035048595727,0.8192186384010108,0.16879423156617618,0.06578463211521306,0.4773013586496177,-0.0029385446148907503,-0.03731541244345559,0.8874978505064713,1.0921354984116292,0.5799697126669984,-0.0029385446148907503,0.10013110654278463
2,448
Ribonucleoside monophosphate biosynthetic process
15
18
2.383002
0.017172
P49915,P30520,P07741,P11172,Q9BZX2,P27708,Q05682,P00492,P55263,O15067,P30085,P22102,P11908,P30566,P12268
Processes and pathways
GO Biological process
msigdb_gobp
430,375,371,679,198,721,690,633,52,766,189,425,372,427,681
766,633,371,679,372,681,425,1019,721,189,375,427,823,430,52,690,1028,198
0.3402816984562314,0.44306035048595727,0.6825574455888234,0.4088101174779366,0.6825574455888234,0.4088101174779366,0.6141744951918664,0.1344676131809928,0.37455059026533083,1.058049730923791,0.6825574455888234,0.6141744951918664,0.3060033706040031,0.6141744951918664,2.1450277845671195,0.4088101174779366,0.1344676131809928,1.0239558333863061
2,448
Tcf dependent signaling in response to wnt
25
57
2.35547
0.018499
P49720,P63104,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P30154,P60900,P55036,P28070,P25787,P30153,Q99460,Q99436,Q13363,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,518,252,408,9,497,416,135,16,496,505,511,40,166,42,164,165,321,56,61,305,67,332,216,354
305,928,884,496,968,497,252,2325,505,1409,67,332,164,640,216,821,42,16,135,165,511,1863,859,946,827,1455,128,9,1052,1705,514,166,40,596,354,688,1185,2397,518,1271,1029,903,61,2373,1347,694,408,2132,794,701,56,321,1688,1431,416,1482,2087
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.16879423156617618,0.5457559728599943,0.8874978505064713,-1.2128777512230653,0.5457559728599943,-0.20935598039970602,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.1262131892268594,0.5457559728599943,-0.5888081853381918,0.271715534183546,0.2031110399977868,0.3060033706040031,-0.24379596346019208,1.262444229636026,4.73422667524134,0.10013110654278463,-0.45066685732428435,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-1.5961860445795646,0.5457559728599943,-0.07170257917698318,0.1344676131809928,0.23741811556684678,2.009558259342313,-1.4566422868933564,-0.14050815550820908,0.4088101174779366,0.648370384959647,-0.8310171614704213,0.3402816984562314,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.4161603820269248,-0.20935598039970602,0.648370384959647,-0.24379596346019208,-0.7617528802884621
2,448
Antigen processing cross presentation
18
47
2.350706
0.018738
P25789,O00231,P20618,P49720,Q9UIQ6,P62191,O75832,Q15008,P49721,P60900,P28070,P25787,P55036,P28074,P28072,P25786,Q99460,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
216,305,67,128,36,354,252,408,9,40,42,164,166,135,16,332,321,56
1776,305,928,884,496,497,2194,252,1303,1404,547,2012,505,67,332,164,640,216,1826,821,42,16,135,2057,859,946,827,128,9,514,166,2231,40,596,1831,354,688,1185,1029,903,408,701,56,321,36,1431,416
-0.5197142211354513,0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-0.9350092561896616,0.8874978505064713,-0.10610013099584205,-0.20935598039970602,0.5115332103198423,-0.7271394986212955,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,-0.554255323491472,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,-0.7617528802884621,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,-1.0044015886837547,2.48323710882666,0.4773013586496177,-0.554255323491472,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,2.5845743832470656,-0.20935598039970602,0.648370384959647
2,448
Pten regulation
19
59
2.340186
0.019274
P49720,O75832,Q15008,P49721,Q86YP4,P28074,P28072,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P27361,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,411,135,16,40,166,42,164,321,56,305,67,311,332,216,354
305,928,884,496,497,1940,252,1366,769,2270,2056,505,1409,67,332,164,640,216,311,821,42,16,135,976,859,1222,946,827,128,9,514,166,40,596,354,688,1185,1271,1029,903,1631,2373,1188,408,2186,1989,1350,411,1721,701,2030,1886,56,321,758,1001,1431,1002,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-0.6579496374044261,0.8874978505064713,-0.17492674178561746,0.3402816984562314,-1.073844393574436,-0.7617528802884621,0.5457559728599943,-0.20935598039970602,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7850662756234686,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.16879423156617618,0.271715534183546,-0.03731541244345559,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-0.07170257917698318,0.1344676131809928,0.23741811556684678,-0.3816652384302993,-1.4566422868933564,-0.0029385446148907503,0.648370384959647,-0.9003323161906817,-0.6925384579151646,-0.14050815550820908,0.648370384959647,-0.45066685732428435,0.4088101174779366,-0.7271394986212955,-0.5888081853381918,2.1111705564621013,0.7850662756234686,0.37455059026533083,0.16879423156617618,-0.20935598039970602,0.16879423156617618,0.648370384959647
2,448
Transcriptional regulation by runx3
21
42
2.336693
0.019455
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,P25789,P62191
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,216,354
305,928,884,496,497,252,2270,505,67,720,332,164,640,216,821,42,16,135,1863,859,946,827,128,9,514,166,40,596,354,688,1185,1029,2318,903,1756,904,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,-1.073844393574436,0.5457559728599943,1.8061474551769805,0.37455059026533083,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,-0.5888081853381918,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,-1.1781012207532906,0.23741811556684678,-0.48518476837761204,0.23741811556684678,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
transporter
14
52
2.336225
0.01948
P54105,O43681,O60830,O95373,Q567V2,O15397,Q9NR77,Q9H2D1,Q99595,P55060,O43772,P41440,Q00169,Q6N075
Functions
Panther Protein class
panther_protein_class
155,185,2,214,37,249,76,47,50,237,23,54,147,27
578,1332,2354,1208,968,249,1530,185,23,672,2,1618,214,1581,54,429,1223,861,1338,1791,1829,595,155,237,1056,1831,147,1548,1064,37,27,1192,997,1112,1962,300,532,2383,800,1286,50,2332,2433,1355,47,704,1967,76,1296,624,1429,926
0.4773013586496177,-0.14050815550820908,-1.352102319336769,-0.03731541244345559,0.16879423156617618,0.8874978505064713,-0.3127085392865689,1.058049730923791,3.3933132177188323,0.4088101174779366,6.897559937683054,-0.3816652384302993,0.9557434311544011,-0.3471813243224761,2.1111705564621013,0.6141744951918664,-0.03731541244345559,0.271715534183546,-0.14050815550820908,-0.5197142211354513,-0.554255323491472,0.4773013586496177,1.1602828560626173,0.9216248161647249,0.10013110654278463,-0.554255323491472,1.1943445509410995,-0.3127085392865689,0.10013110654278463,2.517022513907188,2.8882515754010067,-0.0029385446148907503,0.16879423156617618,0.06578463211521306,-0.6579496374044261,0.8192186384010108,0.5457559728599943,-1.4915115757371213,0.3402816984562314,-0.07170257917698318,2.246559374319931,-1.2476662299708938,-2.1911283167810094,-0.14050815550820908,2.348031579016722,0.4088101174779366,-0.6579496374044261,1.704346800376886,-0.07170257917698318,0.4773013586496177,-0.20935598039970602,0.23741811556684678
2,448
Translation factors
29
36
2.328469
0.019887
Q04637,O75153,O15371,O43432,P20042,P26641,P29692,P11940,Q13144,P55884,O60841,P06730,O75822,P05198,P55010,P60228,P13639,P24534,P60842,P23588,P49770,P19525,Q13347,Q05639,Q9NR50,P62495,O15372,O00303,Q14232
Processes and pathways
WikiPathways
msigdb_wp
379,10,628,629,774,641,510,772,561,402,418,545,420,544,55,315,682,683,556,426,314,820,868,865,105,863,711,847,908
847,628,711,629,418,10,1211,420,544,545,772,682,820,774,426,683,641,510,314,55,402,1663,315,556,863,1147,379,865,561,868,906,908,1501,1153,105,1295
0.271715534183546,0.44306035048595727,0.37455059026533083,0.44306035048595727,0.6141744951918664,4.6673703695070285,-0.03731541244345559,0.6141744951918664,0.5115332103198423,0.5115332103198423,0.3402816984562314,0.4088101174779366,0.3060033706040031,0.3402816984562314,0.6141744951918664,0.4088101174779366,0.44306035048595727,0.5457559728599943,0.7850662756234686,2.1111705564621013,0.648370384959647,-0.4161603820269248,0.7850662756234686,0.5115332103198423,0.271715534183546,0.03142810909569467,0.6825574455888234,0.271715534183546,0.5115332103198423,0.271715534183546,0.23741811556684678,0.23741811556684678,-0.278246784654138,0.03142810909569467,1.5005493340872977,-0.07170257917698318
2,448
calmodulin-related
7
11
2.326793
0.019976
Q9BUP0,O43852,Q99584,Q14257,P31949,P80303,Q02818
Functions
Panther Protein class
panther_protein_class
440,284,341,316,234,26,31
284,503,822,234,1459,26,31,316,1384,341,440
0.8192186384010108,0.5457559728599943,0.3060033706040031,0.9216248161647249,-0.24379596346019208,2.989368530256347,2.753345068924629,0.7850662756234686,-0.17492674178561746,0.7509053294850906,0.6141744951918664
2,448
Adaptive immune system
74
149
2.303607
0.021245
Q15436,P49720,P63104,O75832,Q15008,P49721,Q16763,O43242,O94979,Q9UNM6,P55786,P28072,P28074,O14818,P17980,P30154,P09496,P25788,Q9BUF5,P51665,P68371,P22314,Q7Z6Z7,Q13409,Q14738,Q9BXS5,Q9UIQ6,Q9Y508,Q92530,Q93034,P60900,P55036,P28070,P30153,Q9Y6G9,P25787,Q9ULT8,P68036,P33176,P62195,Q92990,Q9Y4B6,Q14203,P09429,Q99436,O95486,Q99460,P61088,O00231,Q8TBC4,P20618,Q9C0C9,Q9UJW0,P61086,Q96J02,Q15386,P61163,P61081,P25786,Q9UJX4,Q13867,P50570,Q13617,O94822,Q13177,Q10567,P25789,P17612,P62191,P61289,P52888,P62993,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
259,128,518,252,408,9,409,497,499,416,15,16,135,496,505,511,637,640,276,514,406,393,697,562,694,302,36,709,701,570,40,166,42,165,576,164,182,558,291,688,179,450,433,547,56,173,321,432,305,66,67,199,200,335,208,338,336,472,332,488,205,333,602,89,601,600,216,588,354,596,351,651,653,655
667,1206,1776,305,928,884,496,970,497,1210,2194,252,1532,89,715,934,499,2048,849,173,1697,1303,1404,1944,547,637,2012,1823,588,505,891,67,393,332,164,640,216,1826,2155,821,42,16,135,1744,2057,165,511,1177,684,291,859,1140,1222,946,897,1267,827,128,9,333,1864,2302,514,1143,351,1339,1542,1456,166,15,2231,40,1226,472,335,432,336,596,1831,354,688,1185,651,989,518,2381,653,558,406,734,1794,1149,1029,951,600,601,903,562,834,655,602,1347,205,952,738,433,907,1632,694,1105,408,1553,338,259,409,1468,1758,741,955,697,1243,66,701,179,570,1512,208,56,321,2306,1287,276,1924,302,199,1198,1927,36,200,1122,1569,488,1431,182,1002,416,450,709,576
0.4088101174779366,-0.03731541244345559,-0.5197142211354513,0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.16879423156617618,0.5457559728599943,-0.03731541244345559,-0.9350092561896616,0.8874978505064713,-0.3127085392865689,1.6024811499433442,0.37455059026533083,0.2031110399977868,0.5457559728599943,-0.7617528802884621,0.271715534183546,1.0921354984116292,-0.45066685732428435,-0.10610013099584205,-0.20935598039970602,-0.6579496374044261,0.5115332103198423,0.44306035048595727,-0.7271394986212955,-0.554255323491472,0.4773013586496177,0.5457559728599943,0.23741811556684678,1.8061474551769805,0.648370384959647,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,-0.554255323491472,-0.8656683146306153,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,-0.48518476837761204,-0.7617528802884621,1.1262131892268594,0.5457559728599943,-0.0029385446148907503,0.4088101174779366,0.8192186384010108,0.271715534183546,0.03142810909569467,-0.03731541244345559,0.2031110399977868,0.23741811556684678,-0.07170257917698318,0.3060033706040031,1.262444229636026,4.73422667524134,0.7509053294850906,-0.5888081853381918,-1.1433367450359972,0.5457559728599943,0.03142810909569467,0.7167357398101687,-0.14050815550820908,-0.3127085392865689,-0.24379596346019208,1.1262131892268594,4.198836571612469,-1.0044015886837547,2.48323710882666,-0.03731541244345559,0.5799697126669984,0.7509053294850906,0.6141744951918664,0.7509053294850906,0.4773013586496177,-0.554255323491472,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.16879423156617618,0.5457559728599943,-1.4915115757371213,0.44306035048595727,0.5115332103198423,0.648370384959647,0.37455059026533083,-0.5197142211354513,0.03142810909569467,0.1344676131809928,0.2031110399977868,0.4773013586496177,0.4773013586496177,0.23741811556684678,0.5115332103198423,0.3060033706040031,0.44306035048595727,0.4773013586496177,-0.14050815550820908,0.9898537517248991,0.2031110399977868,0.37455059026533083,0.6141744951918664,0.23741811556684678,-0.3816652384302993,0.4088101174779366,0.06578463211521306,0.648370384959647,-0.3127085392865689,0.7509053294850906,0.8874978505064713,0.648370384959647,-0.24379596346019208,-0.48518476837761204,0.37455059026533083,0.2031110399977868,0.4088101174779366,-0.03731541244345559,1.8739790092252244,0.4088101174779366,1.0921354984116292,0.5115332103198423,-0.278246784654138,0.9898537517248991,2.1111705564621013,0.7850662756234686,-1.1433367450359972,-0.07170257917698318,0.8533624771761494,-0.6233729186226958,0.8192186384010108,1.0239558333863061,-0.0029385446148907503,-0.6233729186226958,2.5845743832470656,1.0239558333863061,0.06578463211521306,-0.3127085392865689,0.5799697126669984,-0.20935598039970602,1.0921354984116292,0.16879423156617618,0.648370384959647,0.6141744951918664,0.4088101174779366,0.5115332103198423
2,448
Fcgamma receptor fcgr dependent phagocytosis
10
19
2.274988
0.022907
Q8IV08,P27361,P08238,Q9UQB8,Q7L576,P35579,P07900,P62993,Q9Y2A7,Q92747
Processes and pathways
Reactome Pathways
msigdb_reactome
3,311,585,77,527,592,546,651,764,660
1253,1172,931,1399,546,585,719,311,976,592,1184,1226,1588,651,527,3,660,77,764
-0.07170257917698318,-0.0029385446148907503,0.2031110399977868,-0.20935598039970602,0.5115332103198423,0.4773013586496177,0.37455059026533083,0.7850662756234686,0.16879423156617618,0.4773013586496177,-0.0029385446148907503,-0.03731541244345559,-0.3471813243224761,0.44306035048595727,0.5457559728599943,5.868017095607631,0.44306035048595727,1.704346800376886,0.37455059026533083
2,448
Proteasome regulatory particle
16
18
2.268027
0.023328
O00231,P62191,Q15008,P55036,O43242,Q9UNM6,O00487,P35998,P62195,P17980,Q16186,O00232,Q99460,P51665,Q13200,P48556
Localization
GO Cellular component
msigdb_gocc
305,354,408,166,497,416,884,859,688,505,657,928,321,514,903,827
305,928,884,497,505,859,946,827,514,166,354,688,1185,903,408,657,321,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.271715534183546,0.2031110399977868,0.3060033706040031,0.5457559728599943,1.1262131892268594,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.23741811556684678,0.648370384959647,0.44306035048595727,0.7850662756234686,0.648370384959647
2,448
Translation initiation factor activity
27
34
2.259403
0.023858
Q04637,O15371,O43432,Q7L2H7,P20042,Q13144,P55884,O60841,P06730,O75822,P05198,P55010,Q9UBQ5,P60228,P60842,P23588,Q92905,P49770,Q9Y262,Q13347,Q7Z478,Q9BY44,Q9NR50,O15372,O00303,Q14232,P78344
Functions
GO Molecular function
msigdb_gomf
379,628,629,21,774,561,402,418,545,420,544,55,324,315,556,426,484,314,211,868,872,878,105,711,847,908,654
847,628,711,629,1044,418,1211,420,544,545,774,426,314,55,402,1663,315,556,654,379,561,868,906,908,1501,1153,21,872,484,878,105,324,1295,211
0.271715534183546,0.44306035048595727,0.37455059026533083,0.44306035048595727,0.10013110654278463,0.6141744951918664,-0.03731541244345559,0.6141744951918664,0.5115332103198423,0.5115332103198423,0.3402816984562314,0.6141744951918664,0.7850662756234686,2.1111705564621013,0.648370384959647,-0.4161603820269248,0.7850662756234686,0.5115332103198423,0.44306035048595727,0.6825574455888234,0.5115332103198423,0.271715534183546,0.23741811556684678,0.23741811556684678,-0.278246784654138,0.03142810909569467,3.494172256495323,0.271715534183546,0.5799697126669984,0.271715534183546,1.5005493340872977,0.7850662756234686,-0.07170257917698318,0.9898537517248991
2,448
T cell receptor signaling pathway
8
16
2.251071
0.024381
P51452,P17931,Q9NR50,P49770,P23396,P15311,P61088,Q13144
Processes and pathways
GO Biological process
msigdb_gobp
64,310,105,314,590,424,432,561
1404,424,310,590,976,1140,1266,314,64,432,691,561,908,105,1295,1429
-0.20935598039970602,0.6141744951918664,0.7850662756234686,0.4773013586496177,0.16879423156617618,0.03142810909569467,-0.07170257917698318,0.7850662756234686,1.9078842441946644,0.6141744951918664,0.4088101174779366,0.5115332103198423,0.23741811556684678,1.5005493340872977,-0.07170257917698318,-0.20935598039970602
2,448
Calcium-binding protein
7
16
2.249358
0.02449
Q9Y376,O43852,Q99584,Q14257,P31949,P80303,Q02818
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
248,284,341,316,234,26,31
284,503,1826,234,2093,1341,1459,26,31,316,1384,1642,1320,341,440,248
0.8192186384010108,0.5457559728599943,-0.554255323491472,0.9216248161647249,-0.7963787260487372,-0.14050815550820908,-0.24379596346019208,2.989368530256347,2.753345068924629,0.7850662756234686,-0.17492674178561746,-0.3816652384302993,-0.10610013099584205,0.7509053294850906,0.6141744951918664,0.9216248161647249
2,448
Regulation of cell projection organization
32
81
2.245662
0.024726
P27695,Q04917,Q8N0X7,Q02790,Q00535,Q06787,Q96HC4,P35241,P61586,Q8TC07,P15311,Q15555,Q96G23,O14786,P31150,Q16181,Q4KMP7,Q16658,Q9NR77,Q9UQB8,Q9P258,Q9UHD8,P50570,Q86X55,Q92766,O14976,Q7L576,P20339,Q9NT62,Q9NQW6,Q9H4M9,Q96QK1
Processes and pathways
GO Biological process
msigdb_gobp
254,136,413,158,157,168,438,292,46,178,424,175,59,60,550,605,607,606,76,77,622,623,333,480,97,343,527,114,387,386,384,264
2226,60,343,931,1940,1046,1258,1402,851,972,2119,424,1443,114,1137,719,254,893,550,978,292,1222,1266,1267,1052,646,333,898,1414,1226,1588,46,654,1415,157,1101,158,136,168,1464,1273,601,1230,2342,953,1504,740,175,605,1234,606,793,607,527,480,413,1241,178,97,2030,59,438,264,2282,1928,384,758,2263,386,76,387,2110,622,623,2420,1651,1432,77,2004,764,1081
-1.0044015886837547,2.009558259342313,0.7167357398101687,0.2031110399977868,-0.6579496374044261,0.10013110654278463,-0.07170257917698318,-0.20935598039970602,0.271715534183546,0.16879423156617618,-0.8310171614704213,0.6141744951918664,-0.24379596346019208,1.3985501409397767,0.03142810909569467,0.37455059026533083,0.8874978505064713,0.23741811556684678,0.5115332103198423,0.16879423156617618,0.8192186384010108,-0.03731541244345559,-0.07170257917698318,-0.07170257917698318,0.10013110654278463,0.44306035048595727,0.7509053294850906,0.23741811556684678,-0.20935598039970602,-0.03731541244345559,-0.3471813243224761,2.348031579016722,0.44306035048595727,-0.20935598039970602,1.1602828560626173,0.06578463211521306,1.1602828560626173,1.2283983252262376,1.1262131892268594,-0.24379596346019208,-0.07170257917698318,0.4773013586496177,-0.03731541244345559,-1.2824665524224075,0.2031110399977868,-0.278246784654138,0.37455059026533083,1.0921354984116292,0.4773013586496177,-0.03731541244345559,0.4773013586496177,0.3402816984562314,0.4773013586496177,0.5457559728599943,0.5799697126669984,0.648370384959647,-0.03731541244345559,1.0921354984116292,1.5345340316692926,-0.7271394986212955,2.043435831472084,0.6141744951918664,0.8874978505064713,-1.073844393574436,-0.6233729186226958,0.6825574455888234,0.37455059026533083,-1.0391167407626585,0.6825574455888234,1.704346800376886,0.6825574455888234,-0.7963787260487372,0.4773013586496177,0.4773013586496177,-1.8757910508240416,-0.3816652384302993,-0.20935598039970602,1.704346800376886,-0.6925384579151646,0.37455059026533083,0.10013110654278463
2,448
Actin cytoskeleton reorganization
9
21
2.243073
0.024892
Q13576,Q9UQB8,P61586,Q9Y5K6,P15311,P52565,O14786,P04083,Q00535
Processes and pathways
GO Biological process
msigdb_gobp
33,77,46,327,424,295,60,153,157
60,153,2119,424,1945,1137,592,295,1226,46,651,157,1668,1230,33,475,1419,1677,77,327,1171
2.009558259342313,1.1602828560626173,-0.8310171614704213,0.6141744951918664,-0.6579496374044261,0.03142810909569467,0.4773013586496177,0.8192186384010108,-0.03731541244345559,2.348031579016722,0.44306035048595727,1.1602828560626173,-0.4161603820269248,-0.03731541244345559,2.6183409124581645,0.5799697126669984,-0.20935598039970602,-0.4161603820269248,1.704346800376886,0.7850662756234686,0.03142810909569467
2,448
Tgf beta signaling pathway
6
9
2.237689
0.025241
Q13464,P27361,P30153,P61586,P30154,P63208
Processes and pathways
KEGG Pathways
msigdb_kegg
563,311,165,46,511,653
311,976,165,511,46,653,563,655,1193
0.7850662756234686,0.16879423156617618,1.1262131892268594,0.5457559728599943,2.348031579016722,0.44306035048595727,0.5115332103198423,0.44306035048595727,-0.0029385446148907503
2,448
Initiation factor
26
33
2.234437
0.025454
Q04637,O15371,O43432,Q7L2H7,P20042,Q13144,P55884,O60841,P06730,O75822,P05198,P55010,Q9UBQ5,P60228,P60842,P23588,P49770,Q9Y262,Q13347,Q7Z478,Q9BY44,Q9NR50,O15372,O00303,Q14232,P78344
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
379,628,629,21,774,561,402,418,545,420,544,55,324,315,556,426,314,211,868,872,878,105,711,847,908,654
847,628,711,629,1044,418,1211,420,544,545,774,426,314,55,402,1663,315,556,654,379,561,868,906,908,1501,1153,21,872,878,105,324,1295,211
0.271715534183546,0.44306035048595727,0.37455059026533083,0.44306035048595727,0.10013110654278463,0.6141744951918664,-0.03731541244345559,0.6141744951918664,0.5115332103198423,0.5115332103198423,0.3402816984562314,0.6141744951918664,0.7850662756234686,2.1111705564621013,0.648370384959647,-0.4161603820269248,0.7850662756234686,0.5115332103198423,0.44306035048595727,0.6825574455888234,0.5115332103198423,0.271715534183546,0.23741811556684678,0.23741811556684678,-0.278246784654138,0.03142810909569467,3.494172256495323,0.271715534183546,0.271715534183546,1.5005493340872977,0.7850662756234686,-0.07170257917698318,0.9898537517248991
2,448
Negative regulation of cell projection organization
10
21
2.233758
0.025499
Q9NR77,O14976,P61586,Q04917,Q8N0X7,O14786,P50570,Q02790,Q96G23,Q00535
Processes and pathways
GO Biological process
msigdb_gobp
76,343,46,136,413,60,333,158,59,157
60,343,1402,972,1137,893,550,978,1267,646,333,46,157,158,136,480,413,2030,59,2263,76
2.009558259342313,0.7167357398101687,-0.20935598039970602,0.16879423156617618,0.03142810909569467,0.23741811556684678,0.5115332103198423,0.16879423156617618,-0.07170257917698318,0.44306035048595727,0.7509053294850906,2.348031579016722,1.1602828560626173,1.1602828560626173,1.2283983252262376,0.5799697126669984,0.648370384959647,-0.7271394986212955,2.043435831472084,-1.0391167407626585,1.704346800376886
2,448
Translation factor
20
25
2.233628
0.025508
Q04637,O75153,O15371,O43432,P20042,P29692,P55884,P06730,O75822,P55010,P05198,P60228,P24534,P23588,Q9Y262,Q13347,P62495,P43897,Q14671,P78344
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
379,10,628,629,774,510,402,545,420,55,544,315,683,426,211,868,863,860,909,654
628,629,10,420,544,545,774,426,683,510,860,55,402,1663,315,863,1147,654,379,868,906,909,1153,1297,211
0.44306035048595727,0.44306035048595727,4.6673703695070285,0.6141744951918664,0.5115332103198423,0.5115332103198423,0.3402816984562314,0.6141744951918664,0.4088101174779366,0.5457559728599943,0.271715534183546,2.1111705564621013,0.648370384959647,-0.4161603820269248,0.7850662756234686,0.271715534183546,0.03142810909569467,0.44306035048595727,0.6825574455888234,0.271715534183546,0.23741811556684678,0.23741811556684678,0.03142810909569467,-0.07170257917698318,0.9898537517248991
2,448
protease
16
40
2.22657
0.025976
P25789,Q9NQW7,P20618,P49720,P62191,P60900,P49721,P55036,P28070,P25787,Q9UNM6,P28074,P28072,P25786,Q99460,Q99436
Functions
Panther Protein class
panther_protein_class
216,304,67,128,354,40,9,166,42,164,416,135,16,332,321,56
928,496,497,2116,1899,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,2200,166,40,1543,354,688,1185,903,1796,1385,56,321,918,2390,756,304,1481,416,417,1003
0.2031110399977868,0.5457559728599943,0.5457559728599943,-0.8310171614704213,-0.6233729186226958,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,-0.9350092561896616,1.1262131892268594,2.48323710882666,-0.3127085392865689,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.23741811556684678,-0.5197142211354513,-0.17492674178561746,2.1111705564621013,0.7850662756234686,0.23741811556684678,-1.526392025421465,0.37455059026533083,0.8192186384010108,-0.24379596346019208,0.648370384959647,0.648370384959647,0.16879423156617618
2,448
Regulation of protein targeting
9
15
2.218564
0.026516
Q00535,O14737,Q12955,Q9UBE0,P68036,P55786,Q9UII2,Q9Y4C2,P31150
Processes and pathways
GO Biological process
msigdb_gobp
157,306,219,281,558,15,663,267,550
1253,306,1409,550,782,15,558,157,219,697,1851,281,1121,663,267
-0.07170257917698318,0.7850662756234686,-0.20935598039970602,0.5115332103198423,0.3402816984562314,4.198836571612469,0.5115332103198423,1.1602828560626173,0.9557434311544011,0.4088101174779366,-0.554255323491472,0.8533624771761494,0.06578463211521306,0.44306035048595727,0.8874978505064713
2,448
Negative regulation of neuron projection development
8
14
2.214076
0.026824
Q9NR77,O14976,P61586,Q8N0X7,O14786,Q02790,Q96G23,Q00535
Processes and pathways
GO Biological process
msigdb_gobp
76,343,46,413,60,158,59,157
60,343,972,1137,550,46,157,158,480,413,2030,59,2263,76
2.009558259342313,0.7167357398101687,0.16879423156617618,0.03142810909569467,0.5115332103198423,2.348031579016722,1.1602828560626173,1.1602828560626173,0.5799697126669984,0.648370384959647,-0.7271394986212955,2.043435831472084,-1.0391167407626585,1.704346800376886
2,448
Spinal cord injury
7
15
2.214028
0.026827
P17931,P11802,P27695,P06400,P61586,P04083,P14174
Processes and pathways
WikiPathways
msigdb_wp
310,195,254,287,46,153,63
1402,153,2270,287,583,972,195,63,310,311,254,976,1226,46,2263
-0.20935598039970602,1.1602828560626173,-1.073844393574436,0.8192186384010108,0.4773013586496177,0.16879423156617618,1.0239558333863061,1.941782504586402,0.7850662756234686,0.7850662756234686,0.8874978505064713,0.16879423156617618,-0.03731541244345559,2.348031579016722,-1.0391167407626585
2,448
Rotamase
9
18
2.206892
0.027322
P26885,Q15257,Q9Y3C6,Q9H2H8,Q13526,Q8WUA2,Q02790,Q96AY3,Q13451
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
374,58,109,486,113,358,158,122,120
1009,1787,374,1981,1264,1539,1027,158,1102,120,113,2255,58,358,122,486,489,109
0.1344676131809928,-0.5197142211354513,0.6825574455888234,-0.6925384579151646,-0.07170257917698318,-0.3127085392865689,0.1344676131809928,1.1602828560626173,0.06578463211521306,1.3305126285438011,1.4325574349613057,-1.0391167407626585,2.043435831472084,0.7167357398101687,1.3305126285438011,0.5799697126669984,0.5799697126669984,1.4665571505046475
2,448
Cellular response to chemical stress
25
67
2.201395
0.027708
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,P25786,Q86X55,P25789,P00390,P62191,P30041,P53004
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,40,166,42,164,321,56,305,67,332,480,216,458,354,349,352
305,928,1818,884,496,497,252,1012,458,1174,2287,1405,586,2436,1701,2401,2121,505,1409,67,1578,332,164,640,216,821,42,16,135,349,1862,1949,977,722,859,981,1746,946,827,128,9,514,352,166,40,596,354,688,1185,653,1271,1029,903,655,1347,408,1032,1349,480,1353,701,1283,2423,56,321,1431,416
0.7850662756234686,0.2031110399977868,-0.554255323491472,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.1344676131809928,0.5799697126669984,-0.0029385446148907503,-1.1085844324982728,-0.20935598039970602,0.4773013586496177,-2.47208201584405,-0.45066685732428435,-1.6310994364051572,-0.8310171614704213,0.5457559728599943,-0.20935598039970602,1.8061474551769805,-0.3471813243224761,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.7167357398101687,-0.5888081853381918,-0.6579496374044261,0.16879423156617618,0.37455059026533083,0.271715534183546,0.16879423156617618,-0.48518476837761204,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,0.7167357398101687,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,-0.07170257917698318,0.1344676131809928,0.23741811556684678,0.44306035048595727,-0.14050815550820908,0.648370384959647,0.1344676131809928,-0.14050815550820908,0.5799697126669984,-0.14050815550820908,0.4088101174779366,-0.07170257917698318,-1.910788572894569,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Signaling
6
15
2.184669
0.028913
Q99627,P17931,P43490,Q8WUJ1,Q5JRA6,Q7Z4V5
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
99,310,293,14,176,297
1527,1737,2115,310,396,293,554,1030,1670,176,297,1194,14,99,1121
-0.3127085392865689,-0.48518476837761204,-0.8310171614704213,0.7850662756234686,0.648370384959647,0.8192186384010108,0.5115332103198423,0.1344676131809928,-0.4161603820269248,1.0921354984116292,0.8192186384010108,-0.0029385446148907503,4.399753962147844,1.5345340316692926,0.06578463211521306
2,448
Ubiquitin-conjugating enzyme/RWD-like [IPR016135]
6
9
2.184634
0.028916
Q9C0C9,Q16763,P61086,Q9Y3C8,P61081,P61088
Sequence
InterPro Superfamily
interpro_homologous_superfamily
199,409,335,448,472,432
472,335,432,558,409,1326,199,1476,448
0.5799697126669984,0.7509053294850906,0.6141744951918664,0.5115332103198423,0.648370384959647,-0.10610013099584205,1.0239558333863061,-0.24379596346019208,0.6141744951918664
2,448
Cop9 signalosome
6
9
2.175849
0.029567
Q99627,Q92905,Q9UBW8,Q9UNS2,Q13098,Q7L5N1
Localization
GO Cellular component
msigdb_gocc
99,484,38,417,238,568
1269,651,238,568,484,99,918,38,417
-0.07170257917698318,0.44306035048595727,0.9216248161647249,0.5115332103198423,0.5799697126669984,1.5345340316692926,0.23741811556684678,2.517022513907188,0.648370384959647
2,448
Cell projection assembly
34
69
2.167673
0.030184
Q15691,P27695,P50395,P36405,Q13464,Q06787,P35241,P18085,Q9Y5K6,Q14203,Q8TC07,A6NIH7,O00471,Q15555,P15311,Q9UBB4,O14786,P10155,Q14247,Q16181,Q4KMP7,Q16658,Q9NR77,Q92538,Q9P258,Q9UHD8,P50570,P18206,Q9H223,Q7L576,P20339,Q9NT62,Q9NQW6,Q9H4M9
Processes and pathways
GO Biological process
msigdb_gobp
130,254,646,642,563,168,292,548,327,433,178,53,670,175,424,192,60,678,475,605,607,606,76,745,622,623,333,464,241,527,114,387,386,384
53,670,2226,1005,60,931,1402,1439,1944,851,678,2119,424,548,464,114,1137,254,893,978,292,2016,642,1222,1267,1052,646,333,898,1414,1226,1866,1588,1665,1953,2381,1415,168,1273,563,433,475,835,175,130,605,606,607,527,1239,1241,178,1244,745,999,1769,241,384,386,76,387,622,192,623,1651,2004,764,1081,327
2.1111705564621013,0.4088101174779366,-1.0044015886837547,0.1344676131809928,2.009558259342313,0.2031110399977868,-0.20935598039970602,-0.24379596346019208,-0.6579496374044261,0.271715534183546,0.4088101174779366,-0.8310171614704213,0.6141744951918664,0.5115332103198423,0.5799697126669984,1.3985501409397767,0.03142810909569467,0.8874978505064713,0.23741811556684678,0.16879423156617618,0.8192186384010108,-0.7271394986212955,0.44306035048595727,-0.03731541244345559,-0.07170257917698318,0.10013110654278463,0.44306035048595727,0.7509053294850906,0.23741811556684678,-0.20935598039970602,-0.03731541244345559,-0.5888081853381918,-0.3471813243224761,-0.4161603820269248,-0.6579496374044261,-1.4915115757371213,-0.20935598039970602,1.1262131892268594,-0.07170257917698318,0.5115332103198423,0.6141744951918664,0.5799697126669984,0.3060033706040031,1.0921354984116292,1.262444229636026,0.4773013586496177,0.4773013586496177,0.4773013586496177,0.5457559728599943,-0.03731541244345559,-0.03731541244345559,1.0921354984116292,-0.03731541244345559,0.37455059026533083,0.16879423156617618,-0.48518476837761204,0.9216248161647249,0.6825574455888234,0.6825574455888234,1.704346800376886,0.6825574455888234,0.4773013586496177,1.058049730923791,0.4773013586496177,-0.3816652384302993,-0.6925384579151646,0.37455059026533083,0.10013110654278463,0.7850662756234686
2,448
Antigen receptor mediated signaling pathway
8
17
2.167529
0.030195
P51452,P17931,Q9NR50,P49770,P23396,P15311,P61088,Q13144
Processes and pathways
GO Biological process
msigdb_gobp
64,310,105,314,590,424,432,561
1404,424,310,590,976,1140,1266,314,64,432,691,1030,561,908,105,1295,1429
-0.20935598039970602,0.6141744951918664,0.7850662756234686,0.4773013586496177,0.16879423156617618,0.03142810909569467,-0.07170257917698318,0.7850662756234686,1.9078842441946644,0.6141744951918664,0.4088101174779366,0.1344676131809928,0.5115332103198423,0.23741811556684678,1.5005493340872977,-0.07170257917698318,-0.20935598039970602
2,448
translation initiation factor
20
41
2.162112
0.03061
Q04637,O75153,O15371,P51665,Q7L5N1,Q13144,P55884,O60841,P06730,O75822,P05198,P55010,Q9UBQ5,P60228,P23588,Q92905,P49770,Q9Y262,Q9NR50,P78344
Functions
Panther Protein class
panther_protein_class
379,10,628,514,568,561,402,418,545,420,544,55,324,315,426,484,314,211,105,654
847,884,628,711,629,1044,418,10,1211,420,544,545,774,426,1412,314,514,55,402,1663,315,1147,654,1315,379,561,868,906,908,1153,1798,568,1160,484,878,105,324,1295,1297,211,965
0.271715534183546,0.23741811556684678,0.44306035048595727,0.37455059026533083,0.44306035048595727,0.10013110654278463,0.6141744951918664,4.6673703695070285,-0.03731541244345559,0.6141744951918664,0.5115332103198423,0.5115332103198423,0.3402816984562314,0.6141744951918664,-0.20935598039970602,0.7850662756234686,0.5457559728599943,2.1111705564621013,0.648370384959647,-0.4161603820269248,0.7850662756234686,0.03142810909569467,0.44306035048595727,-0.10610013099584205,0.6825574455888234,0.5115332103198423,0.271715534183546,0.23741811556684678,0.23741811556684678,0.03142810909569467,-0.5197142211354513,0.5115332103198423,0.03142810909569467,0.5799697126669984,0.271715534183546,1.5005493340872977,0.7850662756234686,-0.07170257917698318,-0.07170257917698318,0.9898537517248991,0.2031110399977868
2,448
Programmed cell death
42
89
2.162097
0.030611
P49720,P63104,O75832,Q15008,P49721,P61981,O43242,Q9UNM6,Q04917,P28074,P28072,O14818,P17980,P25788,P51665,P49327,Q13464,Q92530,P60900,P55036,P28070,P25787,O00429,P62195,P41440,P09429,P07900,Q99436,Q99460,O00231,P31946,P20618,P27361,Q8WUM4,P25786,P49354,Q13177,Q9UDY2,P25789,P62191,P61289,O15294
Processes and pathways
Reactome Pathways
msigdb_reactome
128,518,252,408,9,405,497,416,136,135,16,496,505,640,514,644,563,701,40,166,42,164,669,688,54,547,546,56,321,305,684,67,311,744,332,90,601,763,216,354,596,710
305,928,967,669,884,496,710,497,1436,2046,252,1661,1576,2270,2152,546,972,547,2053,2392,1408,2246,505,67,1535,332,164,640,216,858,311,821,42,16,135,976,1219,684,1863,1180,859,981,54,946,827,644,90,128,9,2302,514,1338,166,40,596,405,354,688,730,1185,518,2381,136,1029,2131,1668,1030,601,903,563,1151,1712,1502,1064,408,1419,1189,744,701,2078,56,321,1038,1772,763,1895,1431,1002,416
0.7850662756234686,0.2031110399977868,0.16879423156617618,0.4088101174779366,0.23741811556684678,0.5457559728599943,0.37455059026533083,0.5457559728599943,-0.24379596346019208,-0.7617528802884621,0.8874978505064713,-0.4161603820269248,-0.3471813243224761,-1.073844393574436,-0.8656683146306153,0.5115332103198423,0.16879423156617618,0.5115332103198423,-0.7617528802884621,-1.561283544887797,-0.20935598039970602,-1.0391167407626585,0.5457559728599943,1.8061474551769805,-0.3127085392865689,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.271715534183546,0.7850662756234686,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.16879423156617618,-0.03731541244345559,0.4088101174779366,-0.5888081853381918,-0.0029385446148907503,0.271715534183546,0.16879423156617618,2.1111705564621013,0.2031110399977868,0.3060033706040031,0.44306035048595727,1.6024811499433442,1.262444229636026,4.73422667524134,-1.1433367450359972,0.5457559728599943,-0.14050815550820908,1.1262131892268594,2.48323710882666,0.4773013586496177,0.648370384959647,0.7167357398101687,0.4088101174779366,0.37455059026533083,-0.0029385446148907503,0.5457559728599943,-1.4915115757371213,1.2283983252262376,0.1344676131809928,-0.8310171614704213,-0.4161603820269248,0.1344676131809928,0.4773013586496177,0.23741811556684678,0.5115332103198423,0.03142810909569467,-0.45066685732428435,-0.278246784654138,0.10013110654278463,0.648370384959647,-0.20935598039970602,-0.0029385446148907503,0.37455059026533083,0.4088101174779366,-0.7617528802884621,2.1111705564621013,0.7850662756234686,0.1344676131809928,-0.48518476837761204,0.37455059026533083,-0.5888081853381918,-0.20935598039970602,0.16879423156617618,0.648370384959647
2,448
Amide binding
12
90
2.146029
0.031871
Q15392,P00374,Q9UIQ6,Q8WTV0,Q9Y3C6,P55786,Q13451,P41440,Q00169,Q96AY3,Q9UM22,P24390
Functions
GO Molecular function
msigdb_gomf
1,4,36,41,109,15,120,54,147,122,28,30
452,1527,578,1332,2354,328,2193,1738,1009,672,1660,1820,4,1303,1404,2337,2288,2415,585,637,1176,2012,2272,1215,1018,1262,2123,1787,30,374,1826,270,1981,1264,2247,1581,643,2199,54,1370,1539,1494,1372,644,1496,1223,1747,470,861,1338,1791,15,1026,1831,353,989,147,1027,1870,158,1102,120,1377,1064,1837,1155,1,300,41,2259,532,122,1512,2376,361,2262,2414,1248,879,2282,442,2142,2283,230,843,210,36,28,489,109
0.5799697126669984,-0.3127085392865689,0.4773013586496177,-0.14050815550820908,-1.352102319336769,0.7509053294850906,-0.9350092561896616,-0.48518476837761204,0.1344676131809928,0.4088101174779366,-0.4161603820269248,-0.554255323491472,5.801462288194559,-0.10610013099584205,-0.20935598039970602,-1.2824665524224075,-1.1085844324982728,-1.8408037648208935,0.4773013586496177,0.44306035048595727,-0.0029385446148907503,-0.7271394986212955,-1.073844393574436,-0.03731541244345559,0.1344676131809928,-0.07170257917698318,-0.8310171614704213,-0.5197142211354513,2.753345068924629,0.6825574455888234,-0.554255323491472,0.8533624771761494,-0.6925384579151646,-0.07170257917698318,-1.0391167407626585,-0.3471813243224761,0.44306035048595727,-0.9350092561896616,2.1111705564621013,-0.17492674178561746,-0.3127085392865689,-0.278246784654138,-0.17492674178561746,0.44306035048595727,-0.278246784654138,-0.03731541244345559,-0.48518476837761204,0.5799697126669984,0.271715534183546,-0.14050815550820908,-0.5197142211354513,4.198836571612469,0.1344676131809928,-0.554255323491472,0.7167357398101687,0.16879423156617618,1.1943445509410995,0.1344676131809928,-0.5888081853381918,1.1602828560626173,0.06578463211521306,1.3305126285438011,-0.17492674178561746,0.10013110654278463,-0.554255323491472,0.03142810909569467,7.063268087462211,0.8192186384010108,2.44944534628422,-1.0391167407626585,0.5457559728599943,1.3305126285438011,-0.278246784654138,-1.4566422868933564,0.7167357398101687,-1.0391167407626585,-1.8058267924564126,-0.03731541244345559,0.271715534183546,-1.073844393574436,0.6141744951918664,-0.8310171614704213,-1.073844393574436,0.9557434311544011,0.3060033706040031,0.9898537517248991,2.5845743832470656,2.8208104066536146,0.5799697126669984,1.4665571505046475
2,448