term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Proteasome complex
23
45
3.274606
0.001058
P04792,P48556,Q15386,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P54727,Q99436,P51665,O43396,P20618,O43242,Q5VYK3,P60900,Q15008,Q06323,Q92530
Localization
GO Cellular component
msigdb_gocc
6,260,392,390,275,291,167,581,49,51,588,54,312,69,77,323,220,227,492,484,488,531,397
550,946,1766,730,227,323,1872,6,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1926,312,1102,1368,484,969,697,1503,1463,531,390,488,392,845,492,397,69,581,588,724,727
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,0.7020226932379363,-0.5179988657470733,5.931560240339164,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,-0.5488370384270144,0.730826559921213,0.05748948699344504,-0.12219648225605645,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,0.23542606283924014,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269,0.3237664369124269
2,448
Neddylation
28
62
3.16973
0.001526
Q9UNS2,P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P61081,P28070,P61201,Q8TBC4,Q99436,P61964,P63208,Q9UBW8,P51665,P20618,Q93034,Q99627,O43242,P60900,Q15008,Q5TAQ9,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
404,260,390,275,291,167,581,49,51,588,314,54,571,185,69,67,439,75,77,220,352,224,227,484,488,490,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,314,571,969,67,697,1503,1463,439,531,701,390,973,1109,787,1702,1591,488,1547,2189,1324,1968,490,1593,715,185,397,673,352,69,581,224,1159,1119,75,588,724,404,864
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.730826559921213,0.4409258805823772,0.14667069399718627,1.7705913566526543,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.3237664369124269,0.615366695909301,0.14667069399718627,0.05748948699344504,0.2649184437199032,-0.364669859579678,-0.27334151033073334,0.4992431492624739,-0.24300698162028928,-0.8291051207987041,-0.09212329847709767,-0.5797340545401417,0.4992431492624739,-0.27334151033073334,0.3237664369124269,1.0450797177342925,0.615366695909301,0.3531228099863507,0.6731783026903564,1.7705913566526543,0.4409258805823772,0.9313443171057458,0.027665838086341914,0.05748948699344504,1.7155786256844825,0.4409258805823772,0.3237664369124269,0.615366695909301,0.23542606283924014
2,448
Synthesis of dna
32
68
3.16884
0.00153
Q16763,P51530,P48556,Q9UJX4,Q13200,P25789,P30260,P25787,P49721,Q99460,Q9BRT9,P28072,P28074,Q9UL46,P28070,O00231,Q99436,P41440,P63208,P49642,P39748,Q07864,P51665,P15927,P09884,P20618,O43242,P60900,Q9UJX2,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
264,261,260,285,390,275,519,291,167,581,319,49,51,588,54,550,69,71,439,565,560,598,77,251,464,220,227,484,115,488,531,397
550,946,1766,730,227,1913,1872,464,1689,251,1052,220,738,1310,291,1268,275,655,1727,54,49,51,960,519,658,1497,592,1960,1498,1364,691,560,963,71,1650,260,565,740,1728,167,1060,261,77,1102,484,969,697,1503,1463,439,531,598,390,1109,1074,488,264,397,69,581,319,1940,115,1207,285,588,724,2352
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5488370384270144,-0.5179988657470733,0.5283374011848795,-0.364669859579678,0.8456428872388043,0.087264561932277,0.9313443171057458,0.29436510731780724,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,0.3531228099863507,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.14667069399718627,0.47010609080532134,0.3531228099863507,-0.21272571549189503,0.4117021682718201,-0.5797340545401417,-0.21272571549189503,-0.12219648225605645,0.3237664369124269,0.4409258805823772,0.14667069399718627,1.7431006951795138,-0.33417242136584113,0.8169980768047461,0.4409258805823772,0.29436510731780724,-0.3952226726312979,1.1017238127490079,0.087264561932277,0.8169980768047461,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.4117021682718201,0.615366695909301,0.05748948699344504,0.087264561932277,0.4992431492624739,0.8169980768047461,0.615366695909301,1.7705913566526543,0.4409258805823772,0.730826559921213,-0.5488370384270144,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.3237664369124269,-1.211071046856623
2,448
Mapk6 mapk4 signaling
27
46
3.163224
0.00156
P04792,P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P06493,P17612,P35998,P51665,P25685,P60953,P20618,O43242,Q13177,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
6,260,390,275,291,167,581,49,51,588,54,724,550,69,683,686,691,77,208,595,220,227,626,484,488,531,397
550,946,1766,730,1401,227,1872,6,683,686,1052,220,208,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,595,969,697,1503,1463,531,626,390,488,977,397,69,581,1203,1638,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,-0.15232095828757117,0.9028157215260153,-0.5179988657470733,5.931560240339164,0.3237664369124269,0.3237664369124269,0.087264561932277,0.9313443171057458,0.9598347398148359,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.4117021682718201,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.38243459835151017,0.615366695909301,0.4992431492624739,0.14667069399718627,0.615366695909301,1.7705913566526543,0.4409258805823772,-0.002206819462379813,-0.30372981581819986,0.4409258805823772,0.3237664369124269
2,448
Mitotic g1 phase and g1 s transition
41
65
3.12341
0.001788
P30153,P48556,P00374,Q13200,P63151,P25789,P31350,P27694,P33991,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,P14635,Q99436,P06493,P63208,P49642,P35998,Q07864,P51665,P15927,P33993,P62191,P09884,P20618,P11802,O43242,Q13547,O14818,P60900,P06400,Q15008,P25205,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
618,260,383,390,660,275,520,655,658,291,167,581,49,51,588,54,724,550,555,69,683,439,565,691,598,77,251,592,697,464,220,366,227,747,730,484,734,488,738,531,397
550,946,1766,730,227,1913,1872,383,1171,2142,734,683,464,2268,366,1689,555,251,1052,220,738,1310,291,1268,275,655,1727,54,49,51,618,961,520,658,1497,592,691,1650,260,565,740,1728,167,1060,77,1102,484,969,697,1503,1463,660,439,531,598,390,747,1109,1074,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5488370384270144,-0.5179988657470733,0.615366695909301,-0.002206819462379813,-0.7977141188950565,0.29436510731780724,0.3237664369124269,0.5283374011848795,-0.9553250615605502,0.6442930758559092,-0.364669859579678,0.4409258805823772,0.8456428872388043,0.087264561932277,0.9313443171057458,0.29436510731780724,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,0.3531228099863507,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.38243459835151017,0.14667069399718627,0.47010609080532134,0.3531228099863507,-0.21272571549189503,0.4117021682718201,0.3237664369124269,-0.33417242136584113,0.8169980768047461,0.4409258805823772,0.29436510731780724,-0.3952226726312979,1.1017238127490079,0.087264561932277,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.3531228099863507,0.5573891868193322,0.47010609080532134,0.4117021682718201,0.615366695909301,0.29436510731780724,0.05748948699344504,0.087264561932277,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Translation factor activity rna binding
21
52
3.11077
0.001866
Q7Z2Z2,P60228,Q7L2H7,P78344,O75822,Q04637,P29692,P56537,P23588,Q9Y262,O00178,P55010,P06730,Q7Z478,P55884,P05198,P60842,P24534,P43897,Q9UI10,Q9NR50
Functions
GO Molecular function
msigdb_gomf
536,387,11,529,147,278,292,313,173,453,56,62,552,329,327,463,594,466,95,379,245
56,1484,996,590,1444,1047,769,1488,147,463,552,1175,1357,1220,173,466,1054,292,95,2252,1695,62,327,313,1016,387,594,1276,1629,529,278,1020,1417,1070,974,1508,1150,1420,844,11,536,329,1241,982,673,1598,860,245,1256,379,453,1208
1.825479230161245,-0.21272571549189503,0.11699149062391306,0.4117021682718201,-0.182497206611748,0.087264561932277,0.2649184437199032,-0.21272571549189503,1.1864163358736073,0.5283374011848795,0.4409258805823772,-0.002206819462379813,-0.12219648225605645,-0.03212892744333096,1.0734201781652684,0.5283374011848795,0.087264561932277,0.7595902108481608,1.4664334747935266,-0.9236701828387313,-0.364669859579678,1.798050804303417,0.7020226932379363,0.730826559921213,0.11699149062391306,0.615366695909301,0.4117021682718201,-0.06210093493456228,-0.30372981581819986,0.47010609080532134,0.7883139498979853,0.11699149062391306,-0.15232095828757117,0.087264561932277,0.14667069399718627,-0.21272571549189503,0.027665838086341914,-0.15232095828757117,0.23542606283924014,4.612142867783727,0.47010609080532134,0.7020226932379363,-0.03212892744333096,0.14667069399718627,0.3531228099863507,-0.27334151033073334,0.23542606283924014,0.8742486728862037,-0.03212892744333096,0.6442930758559092,0.5573891868193322,-0.002206819462379813
2,448
Tnfr2 non canonical nf kb pathway
21
40
3.106527
0.001893
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P61081,P28070,Q8TBC4,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,314,54,185,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,314,969,697,1503,1463,439,531,390,1109,488,185,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.730826559921213,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.4992431492624739,1.0450797177342925,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Dectin 1 mediated noncanonical nf kb signaling
21
40
3.106527
0.001893
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P61081,P28070,Q8TBC4,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,314,54,185,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,314,969,697,1503,1463,439,531,390,1109,488,185,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.730826559921213,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.4992431492624739,1.0450797177342925,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Clec7a dectin 1 signaling
21
42
3.071522
0.00213
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P61081,P28070,Q8TBC4,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,314,54,185,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,314,782,969,697,1503,1463,439,531,390,1109,488,1469,185,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.730826559921213,0.2649184437199032,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.4992431492624739,-0.182497206611748,1.0450797177342925,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Protein modification by small protein conjugation
54
132
3.068961
0.002148
Q9NT62,Q9UBT2,Q7Z6E9,Q16763,Q9UPN9,P48506,Q15386,P19474,Q9UJX4,Q9BUN8,Q9ULT8,O75340,Q86WB0,P30260,Q13155,Q9Y3C8,Q6DKJ4,Q9Y4X5,Q13526,Q9UBV2,P61081,Q6PD62,Q8TBC4,A0AVT1,Q5VTR2,Q14258,P61927,P31689,Q99816,P63208,P45974,Q9Y314,Q9UBV8,Q9NW82,Q9UIQ6,P60953,O60678,O75592,Q93034,Q5T4S7,Q7Z6Z7,Q13867,Q96T88,Q04323,Q12899,Q9UJX2,Q00535,P46777,Q13263,P55786,Q5TAQ9,Q9NVI1,Q96J02,Q14139
Processes and pathways
GO Biological process
msigdb_gobp
128,402,395,264,546,385,392,18,285,159,425,160,299,519,573,171,575,178,175,452,314,58,185,302,443,442,192,558,332,439,561,605,604,216,87,595,218,219,352,630,634,347,499,111,486,115,370,369,487,118,490,400,126,533
302,1399,1129,768,1486,1571,218,950,160,219,1872,1490,648,869,1002,1172,1097,2038,1306,18,827,774,1992,1454,519,558,1407,1011,561,1694,369,385,1729,915,1585,1368,118,1541,595,314,968,782,192,1371,1628,1415,439,1066,661,370,111,486,573,487,1659,2025,175,973,1109,787,1702,1591,347,789,533,442,975,1815,2157,2189,392,1324,264,794,883,630,490,443,575,750,58,395,634,715,299,1551,2080,185,933,855,1290,352,638,1860,126,1198,718,499,2303,332,159,2010,2011,1160,937,1940,2014,128,1119,400,1520,216,1830,989,402,452,604,1122,87,115,1207,285,425,2089,1720,546,605,171,1563,178,943,864
0.730826559921213,-0.15232095828757117,0.027665838086341914,0.2649184437199032,-0.21272571549189503,-0.27334151033073334,0.9313443171057458,0.14667069399718627,1.1299908805711318,0.9313443171057458,-0.5179988657470733,-0.21272571549189503,0.3531228099863507,0.2058875754695338,0.11699149062391306,-0.002206819462379813,0.05748948699344504,-0.6727843897556249,-0.09212329847709767,3.7035378773687953,0.23542606283924014,0.2649184437199032,-0.6106905307608944,-0.182497206611748,0.47010609080532134,0.4409258805823772,-0.15232095828757117,0.11699149062391306,0.4409258805823772,-0.364669859579678,0.6442930758559092,0.615366695909301,-0.3952226726312979,0.17630258634391707,-0.27334151033073334,-0.12219648225605645,1.3268575727799916,-0.24300698162028928,0.4117021682718201,0.730826559921213,0.14667069399718627,0.2649184437199032,1.0167021690167521,-0.12219648225605645,-0.30372981581819986,-0.15232095828757117,0.5573891868193322,0.087264561932277,0.3531228099863507,0.6442930758559092,1.3548410508645194,0.4992431492624739,0.4409258805823772,0.4992431492624739,-0.33417242136584113,-0.6417070956037559,1.0734201781652684,0.14667069399718627,0.05748948699344504,0.2649184437199032,-0.364669859579678,-0.27334151033073334,0.6731783026903564,0.2649184437199032,0.47010609080532134,0.5573891868193322,0.14667069399718627,-0.4564966412770062,-0.7977141188950565,-0.8291051207987041,0.615366695909301,-0.09212329847709767,0.8169980768047461,0.2649184437199032,0.2058875754695338,0.38243459835151017,0.4992431492624739,0.5573891868193322,0.4409258805823772,0.29436510731780724,1.825479230161245,0.615366695909301,0.38243459835151017,0.3237664369124269,0.7595902108481608,-0.24300698162028928,-0.7039230664205183,1.0450797177342925,0.17630258634391707,0.23542606283924014,-0.06210093493456228,0.6731783026903564,0.38243459835151017,-0.4872189313453426,1.298839486996753,-0.002206819462379813,0.3237664369124269,0.4992431492624739,-1.0188392846787804,0.7020226932379363,1.1582216374253231,-0.6106905307608944,-0.6106905307608944,0.027665838086341914,0.17630258634391707,-0.5488370384270144,-0.6106905307608944,1.298839486996753,0.05748948699344504,0.615366695909301,-0.21272571549189503,0.9598347398148359,-0.4564966412770062,0.14667069399718627,0.615366695909301,0.5573891868193322,0.4117021682718201,0.05748948699344504,1.5497754824846934,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.5863988415320117,-0.7039230664205183,-0.364669859579678,0.47010609080532134,0.4117021682718201,1.1017238127490079,-0.24300698162028928,1.0734201781652684,0.17630258634391707,0.23542606283924014
2,448
Vegfavegfr2 signaling pathway
51
153
3.051589
0.002276
Q9NYL9,P48735,P04792,Q96PU8,P00338,P78344,P04083,P04179,P61586,Q04637,Q15075,O15460,Q01105,P35579,Q06124,P31948,P42566,Q9NZB2,P62993,O60568,P53680,O00231,P06730,P05387,P15311,P18085,P31689,P51116,P49257,Q6ZRI6,Q7Z478,P35613,Q8WU90,P05198,P60953,Q6Y7W6,O15372,Q96B36,Q9Y520,P20339,Q96CT7,O15355,Q13177,P04406,P18206,Q01844,P40763,P46777,P17655,Q14157,Q96J02
Processes and pathways
WikiPathways
msigdb_wp
401,3,6,542,382,529,15,142,25,278,155,29,154,523,295,521,416,165,293,179,567,550,552,308,432,433,558,436,564,74,329,76,601,463,595,89,590,100,506,230,105,338,626,481,614,119,241,369,367,122,126
1611,550,1042,1484,608,2347,338,996,590,29,1302,179,1403,2174,1987,907,952,1836,382,1354,733,1304,1724,15,142,481,6,463,308,1769,552,1305,1532,1048,871,1002,653,1264,819,1051,432,367,2040,433,687,614,1266,230,1267,873,1221,1137,1494,1362,874,558,521,1139,913,1407,523,76,1269,241,831,1270,1408,416,369,964,1180,3,564,1013,695,1318,436,1273,567,1015,1102,1063,742,595,1370,1998,2102,1183,25,2043,1586,784,2310,1542,293,1066,529,1018,1067,154,119,2103,786,1699,278,295,1700,1885,2002,2044,626,1507,747,122,1737,1782,1075,155,2075,1381,709,2311,1027,711,1191,89,74,1705,329,1473,601,2051,100,105,126,674,542,1599,1335,860,892,1203,1478,1674,401,165,1257,1642,1396,1258,1564,506,767
-0.30372981581819986,0.4409258805823772,0.087264561932277,-0.21272571549189503,0.38243459835151017,-1.211071046856623,0.6731783026903564,0.11699149062391306,0.4117021682718201,2.5016288793513897,-0.09212329847709767,1.0450797177342925,-0.15232095828757117,-0.8291051207987041,-0.6106905307608944,0.17630258634391707,0.14667069399718627,-0.4872189313453426,0.615366695909301,-0.12219648225605645,0.29436510731780724,-0.09212329847709767,-0.3952226726312979,4.161025061636598,1.2145752253051996,0.4992431492624739,5.931560240339164,0.5283374011848795,0.730826559921213,-0.42583141250889395,0.4409258805823772,-0.09212329847709767,-0.24300698162028928,0.087264561932277,0.2058875754695338,0.11699149062391306,0.3531228099863507,-0.06210093493456228,0.23542606283924014,0.087264561932277,0.5573891868193322,0.6442930758559092,-0.6727843897556249,0.5573891868193322,0.3237664369124269,0.38243459835151017,-0.06210093493456228,0.9028157215260153,-0.06210093493456228,0.2058875754695338,-0.03212892744333096,0.027665838086341914,-0.21272571549189503,-0.12219648225605645,0.2058875754695338,0.4409258805823772,0.47010609080532134,0.027665838086341914,0.17630258634391707,-0.15232095828757117,0.47010609080532134,1.6880249517622525,-0.06210093493456228,0.8742486728862037,0.23542606283924014,-0.06210093493456228,-0.15232095828757117,0.5863988415320117,0.6442930758559092,0.14667069399718627,-0.002206819462379813,6.432398994236586,0.4409258805823772,0.11699149062391306,0.3237664369124269,-0.09212329847709767,0.5573891868193322,-0.06210093493456228,0.4409258805823772,0.11699149062391306,0.05748948699344504,0.087264561932277,0.29436510731780724,0.4117021682718201,-0.12219648225605645,-0.6106905307608944,-0.7351237916771668,-0.002206819462379813,2.581598099731636,-0.6727843897556249,-0.27334151033073334,0.2649184437199032,-1.0507002473854663,-0.24300698162028928,0.7595902108481608,0.087264561932277,0.47010609080532134,0.11699149062391306,0.087264561932277,1.1582216374253231,1.3268575727799916,-0.7351237916771668,0.2649184437199032,-0.364669859579678,0.7883139498979853,0.7595902108481608,-0.364669859579678,-0.5179988657470733,-0.6106905307608944,-0.6727843897556249,0.38243459835151017,-0.21272571549189503,0.29436510731780724,1.298839486996753,-0.3952226726312979,-0.42583141250889395,0.087264561932277,1.1582216374253231,-0.7039230664205183,-0.12219648225605645,0.3237664369124269,-1.0507002473854663,0.11699149062391306,0.3237664369124269,-0.002206819462379813,1.522027929261891,1.7155786256844825,-0.364669859579678,0.7020226932379363,-0.182497206611748,0.4117021682718201,-0.6727843897556249,1.4385861401124023,1.4107051071903693,1.298839486996753,0.3531228099863507,0.47010609080532134,-0.27334151033073334,-0.09212329847709767,0.23542606283924014,0.2058875754695338,-0.002206819462379813,-0.182497206611748,-0.33417242136584113,0.615366695909301,1.1299908805711318,-0.03212892744333096,-0.30372981581819986,-0.12219648225605645,-0.03212892744333096,-0.24300698162028928,0.4992431492624739,0.29436510731780724
2,448
S phase
43
77
3.026842
0.002471
Q92530,Q16763,P51530,P48556,Q9UJX4,Q13200,P25789,P27694,P30260,P33991,P25787,P49721,Q99460,Q9BRT9,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P41440,P63208,P49642,P35998,P39748,Q07864,P51665,P33993,P62191,P09884,P20618,P11802,Q8N3U4,O43242,O14818,Q9UJX2,P06400,P60900,Q15008,P25205,Q06323,P15927
Processes and pathways
Reactome Pathways
msigdb_reactome
397,264,261,260,285,390,275,655,519,658,291,167,581,319,49,51,588,54,724,550,69,71,439,565,691,560,598,77,592,697,464,220,366,636,227,730,115,734,484,488,738,531,251
550,946,1766,730,227,1913,866,1872,734,464,366,1689,251,1052,220,738,1310,291,1268,275,655,1727,54,49,51,960,519,658,1497,592,1960,1498,1364,691,560,963,71,1650,260,565,740,1728,167,1060,1318,261,77,1102,484,969,697,1503,1463,439,531,598,390,1109,1074,1783,488,264,847,636,397,69,581,319,1940,1343,115,1207,285,588,724,1562,2352
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5488370384270144,0.2058875754695338,-0.5179988657470733,0.29436510731780724,0.5283374011848795,0.6442930758559092,-0.364669859579678,0.8456428872388043,0.087264561932277,0.9313443171057458,0.29436510731780724,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,0.3531228099863507,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.14667069399718627,0.47010609080532134,0.3531228099863507,-0.21272571549189503,0.4117021682718201,-0.5797340545401417,-0.21272571549189503,-0.12219648225605645,0.3237664369124269,0.4409258805823772,0.14667069399718627,1.7431006951795138,-0.33417242136584113,0.8169980768047461,0.4409258805823772,0.29436510731780724,-0.3952226726312979,1.1017238127490079,0.087264561932277,-0.09212329847709767,0.8169980768047461,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.4117021682718201,0.615366695909301,0.05748948699344504,0.087264561932277,-0.42583141250889395,0.4992431492624739,0.8169980768047461,0.23542606283924014,0.38243459835151017,0.615366695909301,1.7705913566526543,0.4409258805823772,0.730826559921213,-0.5488370384270144,-0.09212329847709767,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.3237664369124269,-0.24300698162028928,-1.211071046856623
2,448
Cytoplasmic translational initiation
7
19
3.014709
0.002572
Q9Y5A9,Q7L2H7,P56537,Q9NR50,P23588,Q04637,P55010
Processes and pathways
GO Biological process
msigdb_gobp
236,11,313,245,173,278,62
996,1047,1220,173,1269,1408,62,313,594,278,1070,974,1420,844,11,329,1337,245,236
0.11699149062391306,0.087264561932277,-0.03212892744333096,1.0734201781652684,-0.06210093493456228,-0.15232095828757117,1.798050804303417,0.730826559921213,0.4117021682718201,0.7883139498979853,0.087264561932277,0.14667069399718627,-0.15232095828757117,0.23542606283924014,4.612142867783727,0.7020226932379363,-0.09212329847709767,0.8742486728862037,0.9028157215260153
2,448
Translation regulator activity nucleic acid binding
24
60
3.002646
0.002676
Q7Z2Z2,P60228,Q7L2H7,P00374,P78344,O75822,Q04637,P29692,P34896,Q6PKG0,P56537,P23588,Q9Y262,O00178,P55010,P06730,Q7Z478,P55884,P05198,P24534,P60842,P43897,Q9UI10,Q9NR50
Functions
GO Molecular function
msigdb_gomf
536,387,11,383,529,147,278,292,42,576,313,173,453,56,62,552,329,327,463,466,594,95,379,245
56,1484,996,590,1444,1047,769,1488,147,383,2142,463,552,1051,1175,1357,1220,173,466,1054,292,42,1363,95,2252,1695,62,327,313,1016,387,594,1276,1629,529,839,278,1020,1417,1070,974,1508,1150,1420,844,576,11,536,329,1241,982,2336,673,1598,860,245,1256,379,453,1208
1.825479230161245,-0.21272571549189503,0.11699149062391306,0.4117021682718201,-0.182497206611748,0.087264561932277,0.2649184437199032,-0.21272571549189503,1.1864163358736073,0.615366695909301,-0.7977141188950565,0.5283374011848795,0.4409258805823772,0.087264561932277,-0.002206819462379813,-0.12219648225605645,-0.03212892744333096,1.0734201781652684,0.5283374011848795,0.087264561932277,0.7595902108481608,2.016625291546481,-0.12219648225605645,1.4664334747935266,-0.9236701828387313,-0.364669859579678,1.798050804303417,0.7020226932379363,0.730826559921213,0.11699149062391306,0.615366695909301,0.4117021682718201,-0.06210093493456228,-0.30372981581819986,0.47010609080532134,0.23542606283924014,0.7883139498979853,0.11699149062391306,-0.15232095828757117,0.087264561932277,0.14667069399718627,-0.21272571549189503,0.027665838086341914,-0.15232095828757117,0.23542606283924014,0.4409258805823772,4.612142867783727,0.47010609080532134,0.7020226932379363,-0.03212892744333096,0.14667069399718627,-1.1467083845303592,0.3531228099863507,-0.27334151033073334,0.23542606283924014,0.8742486728862037,-0.03212892744333096,0.6442930758559092,0.5573891868193322,-0.002206819462379813
2,448
Degradation of gli1 by the proteasome
20
40
2.993203
0.002761
Q92530,P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q96J02
Processes and pathways
Reactome Pathways
msigdb_reactome
397,260,390,275,291,167,581,49,51,588,54,69,439,77,220,227,484,488,531,126
550,946,1766,730,227,1872,686,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,439,531,390,1109,488,397,126,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.3237664369124269,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.4992431492624739,0.615366695909301,1.298839486996753,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Predicted secreted proteins
15
42
2.989898
0.002791
Q8WUJ1,P02656,P14174,P55145,Q9UMX5,P80303,O60888,Q9UM22,P04083,P43490,P81605,O60568,Q02818,Q9HB40,Q99584
Functions
Protein Atlas Protein class
protein_atlas_protein_class
1,2,35,191,106,107,13,177,15,17,19,179,182,94,127
2440,508,179,13,306,1835,2,2385,15,2430,910,1771,653,229,35,1838,368,2019,17,199,741,191,2432,107,19,182,1146,2362,1069,1781,1931,2050,1,1858,127,2405,2219,1254,94,177,106,1867
-4.129611140967758,0.47010609080532134,1.0450797177342925,4.337190227314938,0.730826559921213,-0.4872189313453426,6.997268324204374,-1.504130786089521,4.161025061636598,-3.0085610162180214,0.17630258634391707,-0.42583141250889395,0.3531228099863507,0.9028157215260153,2.3409658129140403,-0.4872189313453426,0.6442930758559092,-0.6417070956037559,3.856772038666039,0.9882872661563274,0.29436510731780724,1.0167021690167521,-3.07948062317972,1.3827901527630164,3.7035378773687953,1.0450797177342925,0.027665838086341914,-1.2757154640498929,0.087264561932277,-0.42583141250889395,-0.5488370384270144,-0.6727843897556249,8.218958800035029,-0.4872189313453426,1.298839486996753,-1.7024966142654252,-0.8605609719945663,-0.03212892744333096,1.4942473318432876,1.0734201781652684,1.4107051071903693,-0.4872189313453426
2,448
Signaling by the b cell receptor bcr
20
39
2.986082
0.002826
P48556,Q13200,P25789,P62993,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,293,291,167,581,49,51,588,54,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,293,439,531,390,1109,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.7595902108481608,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Translation regulator activity
26
75
2.980216
0.00288
Q7Z2Z2,P60228,Q7L2H7,P00374,P78344,O75822,Q14011,Q04637,P29692,P34896,Q6PKG0,P56537,P23588,Q9Y262,O00178,P55010,P06730,P51116,Q7Z478,P55884,P05198,P24534,P60842,P43897,Q9UI10,Q9NR50
Functions
GO Molecular function
msigdb_gomf
536,387,11,383,529,147,150,278,292,42,576,313,173,453,56,62,552,436,329,327,463,466,594,95,379,245
56,1484,947,996,590,1444,1047,769,1488,147,383,2142,463,552,1051,1175,1357,1405,1220,173,466,1054,1312,292,42,1363,1140,1804,95,1057,2252,1014,1695,779,436,62,327,313,1016,387,594,1232,1276,1629,529,839,278,1020,1544,1417,1070,150,974,1508,1150,1420,844,576,11,1028,536,329,1241,982,2336,673,1598,860,245,1638,1256,379,453,1208,809
1.825479230161245,-0.21272571549189503,0.14667069399718627,0.11699149062391306,0.4117021682718201,-0.182497206611748,0.087264561932277,0.2649184437199032,-0.21272571549189503,1.1864163358736073,0.615366695909301,-0.7977141188950565,0.5283374011848795,0.4409258805823772,0.087264561932277,-0.002206819462379813,-0.12219648225605645,-0.15232095828757117,-0.03212892744333096,1.0734201781652684,0.5283374011848795,0.087264561932277,-0.09212329847709767,0.7595902108481608,2.016625291546481,-0.12219648225605645,0.027665838086341914,-0.4564966412770062,1.4664334747935266,0.087264561932277,-0.9236701828387313,0.11699149062391306,-0.364669859579678,0.2649184437199032,0.5573891868193322,1.798050804303417,0.7020226932379363,0.730826559921213,0.11699149062391306,0.615366695909301,0.4117021682718201,-0.03212892744333096,-0.06210093493456228,-0.30372981581819986,0.47010609080532134,0.23542606283924014,0.7883139498979853,0.11699149062391306,-0.24300698162028928,-0.15232095828757117,0.087264561932277,1.1864163358736073,0.14667069399718627,-0.21272571549189503,0.027665838086341914,-0.15232095828757117,0.23542606283924014,0.4409258805823772,4.612142867783727,0.11699149062391306,0.47010609080532134,0.7020226932379363,-0.03212892744333096,0.14667069399718627,-1.1467083845303592,0.3531228099863507,-0.27334151033073334,0.23542606283924014,0.8742486728862037,-0.30372981581819986,-0.03212892744333096,0.6442930758559092,0.5573891868193322,-0.002206819462379813,0.2649184437199032
2,448
Scf skp2 mediated degradation of p27 p21
20
39
2.979312
0.002889
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,P11802,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,439,77,220,227,484,488,366,531,397
550,946,1766,730,227,1872,366,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,439,531,390,1109,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.6442930758559092,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Dna replication
42
73
2.966808
0.003009
Q16763,P51530,P48556,Q9UJX4,Q13200,P25789,P27694,P30260,P33991,P25787,P49721,Q99460,Q9BRT9,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q14974,Q99436,P41440,P63208,P49642,P35998,P39748,Q07864,P51665,P15927,P33993,P62191,P09884,P20618,O43242,O14818,P60900,Q9UJX2,Q15008,P25205,Q06323,Q92530,O60684
Processes and pathways
Reactome Pathways
msigdb_reactome
264,261,260,285,390,275,655,519,658,291,167,581,319,49,51,588,54,724,550,705,69,71,439,565,691,560,598,77,251,592,697,464,220,227,730,484,115,488,738,531,397,250
550,946,1766,730,227,1913,250,1872,464,1689,251,1003,1052,220,738,1310,291,1268,275,655,1727,54,49,51,960,519,658,1497,592,1960,1498,1364,691,560,963,71,1650,260,565,740,1728,167,1060,261,77,1320,1102,484,969,697,1503,1463,2332,439,531,598,390,1109,1074,705,488,264,397,69,581,319,1940,115,1207,285,588,724,2352
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5488370384270144,0.8456428872388043,-0.5179988657470733,0.5283374011848795,-0.364669859579678,0.8456428872388043,0.11699149062391306,0.087264561932277,0.9313443171057458,0.29436510731780724,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,0.3531228099863507,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.14667069399718627,0.47010609080532134,0.3531228099863507,-0.21272571549189503,0.4117021682718201,-0.5797340545401417,-0.21272571549189503,-0.12219648225605645,0.3237664369124269,0.4409258805823772,0.14667069399718627,1.7431006951795138,-0.33417242136584113,0.8169980768047461,0.4409258805823772,0.29436510731780724,-0.3952226726312979,1.1017238127490079,0.087264561932277,0.8169980768047461,1.6880249517622525,-0.09212329847709767,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,-1.1467083845303592,0.5573891868193322,0.47010609080532134,0.4117021682718201,0.615366695909301,0.05748948699344504,0.087264561932277,0.3237664369124269,0.4992431492624739,0.8169980768047461,0.615366695909301,1.7705913566526543,0.4409258805823772,0.730826559921213,-0.5488370384270144,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.3237664369124269,-1.211071046856623
2,448
Cyclin a cdk2 associated events at s phase entry
20
40
2.960868
0.003068
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,P11802,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,439,77,220,227,484,488,366,531,397
550,946,1766,730,227,1872,734,366,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,439,531,390,1109,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.29436510731780724,0.6442930758559092,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Translation factor
14
25
2.955126
0.003125
O75153,P60228,P29692,P55884,P78344,P56537,P23588,O75822,Q9Y262,P05198,P24534,Q04637,P55010,P43897
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
9,387,292,327,529,313,173,147,453,463,466,278,62,95
996,1444,9,147,463,552,1220,173,466,292,95,62,327,313,387,1276,1629,529,278,1070,974,1021,844,1761,453
0.11699149062391306,-0.182497206611748,5.057346280317093,1.1864163358736073,0.5283374011848795,0.4409258805823772,-0.03212892744333096,1.0734201781652684,0.5283374011848795,0.7595902108481608,1.4664334747935266,1.798050804303417,0.7020226932379363,0.730826559921213,0.615366695909301,-0.06210093493456228,-0.30372981581819986,0.47010609080532134,0.7883139498979853,0.087264561932277,0.14667069399718627,0.11699149062391306,0.23542606283924014,-0.3952226726312979,0.5573891868193322
2,448
C type lectin receptors clrs
27
44
2.948836
0.00319
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P61081,P28070,Q8TBC4,Q9UNM6,O00231,Q99436,P17612,P63208,P35998,P51665,P62191,P20618,O43242,Q13177,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,314,54,185,724,550,69,686,439,691,77,697,220,227,626,484,488,531,397
550,946,1766,730,227,1872,686,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,314,782,969,697,1503,1463,439,531,626,390,1109,488,1469,185,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.3237664369124269,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.730826559921213,0.2649184437199032,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.38243459835151017,0.615366695909301,0.05748948699344504,0.4992431492624739,-0.182497206611748,1.0450797177342925,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Peptidase complex
25
52
2.942367
0.003257
P61009,P04792,P48556,Q15386,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P54727,Q99436,O43396,P51665,P20618,Q15008,O43242,Q5VYK3,P60900,P17655,Q06323,Q92530
Localization
GO Cellular component
msigdb_gocc
131,6,260,392,390,275,291,167,581,49,51,588,54,312,69,323,77,220,488,227,492,484,367,531,397
550,946,1766,730,227,323,1872,6,367,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1926,312,1102,1368,484,131,969,697,1503,1463,1697,531,390,1886,488,392,845,492,397,799,69,581,588,724,2380,1908,727
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,0.7020226932379363,-0.5179988657470733,5.931560240339164,0.6442930758559092,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,-0.5488370384270144,0.730826559921213,0.05748948699344504,-0.12219648225605645,0.4992431492624739,1.2707865591544374,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,-0.364669859579678,0.47010609080532134,0.615366695909301,-0.5179988657470733,0.4992431492624739,0.615366695909301,0.23542606283924014,0.4992431492624739,0.615366695909301,0.2649184437199032,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269,-1.4058330257519098,-0.5179988657470733,0.3237664369124269
2,448
Transcriptional regulation by runx2
31
51
2.939678
0.003286
Q96PK6,P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,P14635,Q99436,P06493,P63208,P35998,P51665,P62191,P20618,O43242,O14818,P17931,P06400,Q07812,P60900,Q15008,P11802,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
798,260,390,275,291,167,581,49,51,588,54,724,550,555,69,683,439,691,77,697,220,227,730,368,734,485,484,488,366,531,397
550,946,1766,730,227,1872,734,683,366,555,368,1052,220,1310,291,1268,275,1221,1727,54,49,51,1494,691,1270,1650,260,1728,167,1318,77,1102,484,969,697,1503,1463,439,531,485,390,1109,789,488,397,798,69,581,588,1720,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.29436510731780724,0.3237664369124269,0.6442930758559092,0.4409258805823772,0.6442930758559092,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.03212892744333096,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.21272571549189503,0.3237664369124269,-0.06210093493456228,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,-0.09212329847709767,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.4992431492624739,0.615366695909301,0.05748948699344504,0.2649184437199032,0.4992431492624739,0.615366695909301,0.2649184437199032,1.7705913566526543,0.4409258805823772,0.4409258805823772,-0.364669859579678,0.3237664369124269
2,448
Initiation factor
16
33
2.938453
0.003299
P60228,Q7Z478,Q7L2H7,P55884,Q9UI10,P78344,P56537,Q9NR50,P23588,O75822,Q9Y262,P05198,P60842,Q04637,P55010,P06730
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
387,329,11,327,379,529,313,245,173,147,453,463,594,278,62,552
1484,996,590,1444,1047,769,1488,147,463,552,1220,173,1695,62,327,313,387,594,529,278,1417,1070,974,1150,1420,844,11,329,860,245,1256,379,453
-0.21272571549189503,0.11699149062391306,0.4117021682718201,-0.182497206611748,0.087264561932277,0.2649184437199032,-0.21272571549189503,1.1864163358736073,0.5283374011848795,0.4409258805823772,-0.03212892744333096,1.0734201781652684,-0.364669859579678,1.798050804303417,0.7020226932379363,0.730826559921213,0.615366695909301,0.4117021682718201,0.47010609080532134,0.7883139498979853,-0.15232095828757117,0.087264561932277,0.14667069399718627,0.027665838086341914,-0.15232095828757117,0.23542606283924014,4.612142867783727,0.7020226932379363,0.23542606283924014,0.8742486728862037,-0.03212892744333096,0.6442930758559092,0.5573891868193322
2,448
Translation factors
15
36
2.92779
0.003414
O75153,P60228,P29692,P55884,P60842,P56537,Q9UI10,Q9NR50,P23588,O75822,P05198,P24534,Q04637,P55010,P06730
Processes and pathways
WikiPathways
msigdb_wp
9,387,292,327,594,313,379,245,173,147,463,466,278,62,552
1484,996,590,1444,769,9,1488,147,463,552,1051,1175,1405,1220,173,466,1054,292,1695,62,327,313,387,594,1276,1629,278,1020,1417,1070,974,1150,1420,844,245,379
-0.21272571549189503,0.11699149062391306,0.4117021682718201,-0.182497206611748,0.2649184437199032,5.057346280317093,-0.21272571549189503,1.1864163358736073,0.5283374011848795,0.4409258805823772,0.087264561932277,-0.002206819462379813,-0.15232095828757117,-0.03212892744333096,1.0734201781652684,0.5283374011848795,0.087264561932277,0.7595902108481608,-0.364669859579678,1.798050804303417,0.7020226932379363,0.730826559921213,0.615366695909301,0.4117021682718201,-0.06210093493456228,-0.30372981581819986,0.7883139498979853,0.11699149062391306,-0.15232095828757117,0.087264561932277,0.14667069399718627,0.027665838086341914,-0.15232095828757117,0.23542606283924014,0.8742486728862037,0.6442930758559092
2,448
Magnesium ion binding
7
58
2.925094
0.003444
Q9H773,Q9NWX6,P48735,P34913,O75874,Q969T7,P36871
Functions
GO Molecular function
msigdb_gomf
0,102,3,4,7,125,153
458,1566,2202,429,2036,160,7,409,1263,1770,2268,872,2350,1579,2113,686,1053,1362,656,1222,4,1879,1583,153,560,276,385,1271,3,565,2253,1227,566,1585,1017,597,976,1026,489,1027,752,125,497,2238,1599,892,2030,0,377,1674,2384,1718,102,2107,2136,402,2406,898
0.5283374011848795,-0.27334151033073334,-0.8605609719945663,0.5573891868193322,-0.6727843897556249,1.1299908805711318,5.594030281929976,0.5863988415320117,-0.06210093493456228,-0.42583141250889395,-0.9553250615605502,0.2058875754695338,-1.211071046856623,-0.27334151033073334,-0.7663872448501347,0.3237664369124269,0.087264561932277,-0.12219648225605645,0.3531228099863507,-0.03212892744333096,6.194698272515258,-0.5179988657470733,-0.27334151033073334,1.1582216374253231,0.4409258805823772,0.7883139498979853,0.615366695909301,-0.06210093493456228,6.432398994236586,0.4409258805823772,-0.9236701828387313,-0.03212892744333096,0.4409258805823772,-0.27334151033073334,0.11699149062391306,0.4117021682718201,0.14667069399718627,0.11699149062391306,0.4992431492624739,0.11699149062391306,0.29436510731780724,1.298839486996753,0.4992431492624739,-0.8920824087947153,-0.27334151033073334,0.2058875754695338,-0.6417070956037559,10.572089480261452,0.6442930758559092,-0.33417242136584113,-1.4712982411373168,-0.364669859579678,1.4385861401124023,-0.7351237916771668,-0.7663872448501347,0.615366695909301,-1.7024966142654252,0.2058875754695338
2,448
Regulation of mrna stability by proteins that bind au rich elements
24
58
2.914147
0.003567
P04792,Q92945,Q92973,P48556,Q13200,Q9Y2L1,Q04637,P25789,Q01105,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
6,541,266,260,390,427,278,275,154,291,167,581,49,51,588,54,69,77,220,227,484,488,531,397
550,946,1766,730,1401,227,1872,6,1050,1051,1052,220,1310,291,1268,275,1727,54,49,51,1455,1499,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,698,154,278,1779,531,390,1189,880,488,1546,2003,2311,1325,397,541,266,2236,69,581,1943,1293,588,724,427
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,-0.15232095828757117,0.9028157215260153,-0.5179988657470733,5.931560240339164,0.087264561932277,0.087264561932277,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.182497206611748,-0.21272571549189503,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.3237664369124269,1.1582216374253231,0.7883139498979853,-0.42583141250889395,0.47010609080532134,0.615366695909301,-0.002206819462379813,0.2058875754695338,0.4992431492624739,-0.24300698162028928,-0.6106905307608944,-1.0507002473854663,-0.09212329847709767,0.615366695909301,0.47010609080532134,0.8169980768047461,-0.8920824087947153,1.7705913566526543,0.4409258805823772,-0.5488370384270144,-0.06210093493456228,0.4409258805823772,0.3237664369124269,0.5863988415320117
2,448
Intracellular protein containing complex
86
185
2.908158
0.003636
Q9C0C2,P04792,Q9NXV2,Q5VZE5,P30260,Q99460,P28072,P28074,Q9UL46,P28070,Q15257,Q6PD62,P54619,P30876,O00231,Q15014,P06730,Q99436,P61964,P49642,Q07864,Q9UBV8,P51665,Q6IAA8,Q6IA86,Q9H9Y6,Q9UJX2,P30153,Q9NT62,Q92499,P41227,Q9NXR7,P68036,P63151,Q9BUN8,O94880,O95163,O75340,P10644,Q86VP6,P49721,Q9Y4X5,Q3B726,Q9Y5K5,Q9GZZ1,Q9UNM6,P12956,P17612,P35998,P62191,P20618,O43242,Q9NR50,P49354,Q9BXJ9,Q9BVC5,Q16763,P48556,Q9UJX4,P25789,Q8TEY7,P25787,P54727,O43396,Q93034,Q5TBB1,Q92530,Q5BKZ1,Q15386,Q13200,Q92600,Q8NCA5,Q9HB71,Q9UBV2,Q9Y296,Q5VTR2,O95602,P63208,P09884,Q96S59,Q5VYK3,P60900,Q15008,Q5TAQ9,Q06323,Q14139
Localization
GO Cellular component
msigdb_gocc
545,6,31,34,519,581,49,51,588,54,55,58,568,557,550,63,552,69,67,565,598,604,77,633,632,642,115,618,128,672,135,146,661,660,159,649,651,160,654,715,167,178,710,727,721,724,685,686,691,697,220,227,245,242,255,254,264,260,285,275,300,291,312,323,352,348,397,393,392,390,422,447,450,452,454,443,431,439,464,498,492,484,488,490,531,533
903,1041,550,946,1442,1766,1128,730,1871,1129,1349,1613,949,227,323,1571,2174,950,160,1872,1095,649,651,1573,431,2110,6,552,1172,464,654,685,1174,1623,686,1052,1307,2323,1308,1582,220,1803,738,1310,291,1268,275,1727,54,49,51,960,618,961,519,557,1138,691,1011,135,1408,1650,260,242,565,740,1728,167,1461,77,1926,568,312,1102,1368,1842,484,782,969,67,697,1503,1463,2273,660,439,1698,661,1416,531,1544,598,1589,390,1109,787,1702,1591,533,843,488,63,55,2189,392,845,1324,264,710,848,393,490,348,1239,443,492,34,632,633,750,58,1028,715,1707,1330,1551,447,300,672,397,422,933,352,857,1389,1117,498,1861,69,581,1899,159,254,255,545,1901,1339,721,2425,1940,1477,642,450,1084,245,1438,128,1119,146,31,1481,1522,452,604,115,1207,285,588,1166,1642,1720,724,1608,1864,1906,454,2352,1038,1643,2380,1563,1345,178,727,1798
0.17630258634391707,0.087264561932277,0.4409258805823772,0.14667069399718627,-0.182497206611748,-0.42583141250889395,0.027665838086341914,0.29436510731780724,-0.5179988657470733,0.027665838086341914,-0.12219648225605645,-0.30372981581819986,0.14667069399718627,0.9028157215260153,0.7020226932379363,-0.27334151033073334,-0.8291051207987041,0.14667069399718627,1.1299908805711318,-0.5179988657470733,0.05748948699344504,0.3531228099863507,0.3531228099863507,-0.27334151033073334,0.5573891868193322,-0.7663872448501347,5.931560240339164,0.4409258805823772,-0.002206819462379813,0.5283374011848795,0.3531228099863507,0.3237664369124269,-0.002206819462379813,-0.30372981581819986,0.3237664369124269,0.087264561932277,-0.09212329847709767,-1.114634054017247,-0.09212329847709767,-0.27334151033073334,0.9313443171057458,-0.4564966412770062,0.29436510731780724,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.14667069399718627,0.38243459835151017,0.14667069399718627,0.47010609080532134,0.4409258805823772,0.027665838086341914,0.3237664369124269,0.11699149062391306,1.2426985519939489,-0.15232095828757117,-0.33417242136584113,0.8169980768047461,0.8742486728862037,0.4409258805823772,0.29436510731780724,-0.3952226726312979,1.1017238127490079,-0.182497206611748,1.6880249517622525,-0.5488370384270144,0.4409258805823772,0.730826559921213,0.05748948699344504,-0.12219648225605645,-0.4872189313453426,0.4992431492624739,0.2649184437199032,0.14667069399718627,1.7705913566526543,0.3237664369124269,-0.21272571549189503,-0.182497206611748,-0.9553250615605502,0.3531228099863507,0.5573891868193322,-0.364669859579678,0.3531228099863507,-0.15232095828757117,0.47010609080532134,-0.24300698162028928,0.4117021682718201,-0.27334151033073334,0.615366695909301,0.05748948699344504,0.2649184437199032,-0.364669859579678,-0.27334151033073334,0.47010609080532134,0.23542606283924014,0.4992431492624739,1.798050804303417,1.8528768241204838,-0.8291051207987041,0.615366695909301,0.23542606283924014,-0.09212329847709767,0.8169980768047461,0.3237664369124269,0.23542606283924014,0.615366695909301,0.4992431492624739,0.6731783026903564,-0.03212892744333096,0.5573891868193322,0.4992431492624739,2.367811073932946,0.38243459835151017,0.38243459835151017,0.29436510731780724,1.825479230161245,0.11699149062391306,0.3237664369124269,-0.364669859579678,-0.09212329847709767,-0.24300698162028928,0.5573891868193322,0.7595902108481608,0.3531228099863507,0.615366695909301,0.5863988415320117,0.17630258634391707,0.6731783026903564,0.23542606283924014,-0.12219648225605645,0.05748948699344504,0.4992431492624739,-0.4872189313453426,1.7705913566526543,0.4409258805823772,-0.5179988657470733,1.1582216374253231,0.8456428872388043,0.8456428872388043,0.47010609080532134,-0.5179988657470733,-0.09212329847709767,0.3237664369124269,-2.691980254123364,-0.5488370384270144,-0.182497206611748,0.38243459835151017,0.5573891868193322,0.087264561932277,0.8742486728862037,-0.15232095828757117,1.298839486996753,0.05748948699344504,1.2145752253051996,2.5016288793513897,-0.182497206611748,-0.21272571549189503,0.5573891868193322,0.4117021682718201,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.027665838086341914,-0.30372981581819986,-0.364669859579678,0.3237664369124269,-0.27334151033073334,-0.4872189313453426,-0.5179988657470733,0.5573891868193322,-1.211071046856623,0.11699149062391306,-0.30372981581819986,-1.4058330257519098,-0.24300698162028928,-0.09212329847709767,1.0734201781652684,0.3237664369124269,-0.42583141250889395
2,448
Beta catenin independent wnt signaling
21
49
2.90609
0.00366
P48556,Q13200,P61586,P25789,P09497,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P53680,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,25,275,411,291,167,581,49,51,588,54,567,69,77,220,227,484,488,531,397
550,946,1766,730,227,1872,999,1836,1048,955,411,1052,220,1310,291,1268,275,1727,54,49,51,1407,691,1650,260,1728,167,77,567,1102,484,969,25,697,1503,1463,1278,1067,531,390,2072,488,397,1514,69,581,1203,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.11699149062391306,-0.4872189313453426,0.087264561932277,0.14667069399718627,0.5863988415320117,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.15232095828757117,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.4409258805823772,0.05748948699344504,0.4992431492624739,0.14667069399718627,2.581598099731636,0.3237664369124269,-0.21272571549189503,-0.182497206611748,-0.06210093493456228,0.087264561932277,0.47010609080532134,0.615366695909301,-0.7039230664205183,0.4992431492624739,0.615366695909301,-0.21272571549189503,1.7705913566526543,0.4409258805823772,-0.002206819462379813,0.4409258805823772,0.3237664369124269
2,448
Pcp ce pathway
21
47
2.900154
0.00373
P48556,Q13200,P61586,P25789,P09497,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,P53680,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,25,275,411,291,167,581,49,51,588,54,567,69,77,220,227,484,488,531,397
550,946,1766,730,227,1872,999,1836,1048,955,411,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,567,1102,484,969,25,697,1503,1463,1278,1067,531,390,2072,488,397,1514,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.11699149062391306,-0.4872189313453426,0.087264561932277,0.14667069399718627,0.5863988415320117,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.4409258805823772,0.05748948699344504,0.4992431492624739,0.14667069399718627,2.581598099731636,0.3237664369124269,-0.21272571549189503,-0.182497206611748,-0.06210093493456228,0.087264561932277,0.47010609080532134,0.615366695909301,-0.7039230664205183,0.4992431492624739,0.615366695909301,-0.21272571549189503,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Switching of origins to a post replicative state
24
51
2.898196
0.003753
Q16763,P48556,Q9UJX4,Q13200,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,O00231,Q99436,P63208,P51665,P20618,O43242,P60900,Q9UJX2,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
264,260,285,390,275,519,291,167,581,49,51,588,54,550,69,439,77,220,227,484,115,488,531,397
550,946,1766,730,227,1913,1872,1052,220,738,1310,291,1268,275,1727,54,49,51,519,658,1497,592,691,1650,260,1728,167,1060,77,1102,484,969,697,1503,1463,439,531,390,1109,1074,488,264,397,69,581,1940,115,1207,285,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5488370384270144,-0.5179988657470733,0.087264561932277,0.9313443171057458,0.29436510731780724,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.47010609080532134,0.3531228099863507,-0.21272571549189503,0.4117021682718201,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,0.087264561932277,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.087264561932277,0.4992431492624739,0.8169980768047461,0.615366695909301,1.7705913566526543,0.4409258805823772,-0.5488370384270144,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.3237664369124269
2,448
Defective cftr causes cystic fibrosis
20
40
2.887109
0.003888
P48556,Q13200,Q9BUN8,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,159,275,291,167,581,49,51,452,588,54,69,77,220,227,484,488,531,397
550,946,1766,730,227,1872,2017,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,1368,484,969,697,1503,1463,531,390,488,397,69,581,159,452,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.6417070956037559,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,-0.12219648225605645,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,1.1582216374253231,0.5573891868193322,0.4409258805823772,0.3237664369124269
2,448
Abc transporter disorders
20
40
2.887109
0.003888
P48556,Q13200,Q9BUN8,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,159,275,291,167,581,49,51,452,588,54,69,77,220,227,484,488,531,397
550,946,1766,730,227,1872,2017,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,1368,484,969,697,1503,1463,531,390,488,397,69,581,159,452,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.6417070956037559,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,-0.12219648225605645,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,1.1582216374253231,0.5573891868193322,0.4409258805823772,0.3237664369124269
2,448
Downstream signaling events of b cell receptor bcr
19
38
2.881054
0.003963
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,439,531,390,1109,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Fceri mediated nf kb activation
19
40
2.874816
0.004043
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,782,969,697,1503,1463,439,531,390,1109,488,1469,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.2649184437199032,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.4992431492624739,-0.182497206611748,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Fc epsilon receptor fceri signaling
20
44
2.873574
0.004059
P48556,Q13200,P25789,P62993,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,293,291,167,581,49,51,588,54,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1221,1727,54,49,51,1494,691,1650,260,1728,167,77,1102,484,782,969,697,1503,1463,293,439,531,626,390,1109,488,1469,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.03212892744333096,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.21272571549189503,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.2649184437199032,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.7595902108481608,0.5573891868193322,0.47010609080532134,0.38243459835151017,0.615366695909301,0.05748948699344504,0.4992431492624739,-0.182497206611748,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Translation initiation factor activity
16
34
2.869587
0.00411
P60228,Q7Z478,Q7L2H7,P55884,Q9UI10,P78344,P56537,Q9NR50,P23588,O75822,Q9Y262,P05198,P60842,Q04637,P55010,P06730
Functions
GO Molecular function
msigdb_gomf
387,329,11,327,379,529,313,245,173,147,453,463,594,278,62,552
1484,996,590,1444,1047,769,1488,147,463,552,1220,173,1695,62,327,313,387,594,529,278,1417,1070,974,1150,1420,844,11,329,673,860,245,1256,379,453
-0.21272571549189503,0.11699149062391306,0.4117021682718201,-0.182497206611748,0.087264561932277,0.2649184437199032,-0.21272571549189503,1.1864163358736073,0.5283374011848795,0.4409258805823772,-0.03212892744333096,1.0734201781652684,-0.364669859579678,1.798050804303417,0.7020226932379363,0.730826559921213,0.615366695909301,0.4117021682718201,0.47010609080532134,0.7883139498979853,-0.15232095828757117,0.087264561932277,0.14667069399718627,0.027665838086341914,-0.15232095828757117,0.23542606283924014,4.612142867783727,0.7020226932379363,0.3531228099863507,0.23542606283924014,0.8742486728862037,-0.03212892744333096,0.6442930758559092,0.5573891868193322
2,448
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
22
45
2.865668
0.004161
Q16763,P48556,Q9UJX4,Q13200,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q9UJX2,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
264,260,285,390,275,519,291,167,581,49,51,588,54,69,77,220,227,484,115,488,531,397
550,946,1766,730,2091,227,1872,734,1052,220,1310,291,1268,275,1727,54,49,51,519,691,1650,260,1728,167,77,1585,1102,484,969,697,1503,1463,531,390,488,264,397,69,581,1940,115,1207,285,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,-0.7351237916771668,0.9028157215260153,-0.5179988657470733,0.29436510731780724,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.47010609080532134,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,-0.27334151033073334,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.8169980768047461,0.615366695909301,1.7705913566526543,0.4409258805823772,-0.5488370384270144,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.3237664369124269
2,448
Regulation of runx2 expression and activity
19
42
2.860127
0.004235
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1270,1650,260,1728,167,1318,77,1102,484,969,697,1503,1463,439,531,390,1109,789,488,397,69,581,588,1720,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.06210093493456228,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,-0.09212329847709767,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.2649184437199032,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,-0.364669859579678,0.3237664369124269
2,448
Hedgehog ligand biogenesis
19
39
2.854134
0.004315
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,452,588,54,69,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1532,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,1368,484,969,697,1503,1463,531,390,488,397,69,581,452,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.24300698162028928,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,-0.12219648225605645,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.5573891868193322,0.4409258805823772,0.3237664369124269
2,448
Proteasome
18
35
2.850015
0.004372
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
KEGG Pathways
msigdb_kegg
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Negative regulation of notch4 signaling
19
39
2.849854
0.004374
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,698,439,531,390,1109,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.3237664369124269,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Apc c mediated degradation of cell cycle proteins
24
51
2.840247
0.004508
Q16763,P48556,Q9UJX4,Q13200,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,O00231,Q99436,P63208,P51665,P20618,O43242,P60900,Q9UJX2,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
264,260,285,390,275,519,291,167,581,49,51,588,54,550,69,439,77,220,227,484,115,488,531,397
550,946,1766,730,2091,227,768,1571,1872,734,683,555,1052,220,1310,291,1268,275,1727,54,49,51,519,691,1650,260,1728,167,77,1585,1102,484,969,697,1503,1463,439,531,390,1109,488,264,397,69,581,1940,115,1207,285,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,-0.7351237916771668,0.9028157215260153,0.2649184437199032,-0.27334151033073334,-0.5179988657470733,0.29436510731780724,0.3237664369124269,0.4409258805823772,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.47010609080532134,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,-0.27334151033073334,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.4992431492624739,0.8169980768047461,0.615366695909301,1.7705913566526543,0.4409258805823772,-0.5488370384270144,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.3237664369124269
2,448
Degradation of beta catenin by the destruction complex
20
47
2.836501
0.004561
P48556,Q13200,P25789,Q13363,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,32,291,167,581,49,51,588,54,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,618,961,1407,691,1650,260,833,1728,167,1318,77,1102,1731,484,969,697,1503,1463,439,531,390,32,747,1109,843,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.38243459835151017,0.14667069399718627,-0.15232095828757117,0.3237664369124269,-0.33417242136584113,0.8169980768047461,0.23542606283924014,-0.3952226726312979,1.1017238127490079,-0.09212329847709767,1.6880249517622525,0.05748948699344504,-0.3952226726312979,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,2.474919285820168,0.29436510731780724,0.05748948699344504,0.23542606283924014,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Ubl conjugation pathway
45
92
2.833524
0.004604
Q9NT62,Q9UBT2,Q15018,Q7Z6E9,Q16763,Q9UPN9,Q15386,Q9NXR7,P19474,Q9UJX4,P68036,Q9ULT8,Q9H4L4,O94874,Q8TEY7,Q86WB0,P30260,Q9Y2K7,Q9Y3C8,Q86VP6,Q9Y4X5,Q96MG7,Q9HB71,P61081,P54727,Q5VTR2,Q8TBC4,A0AVT1,Q14258,Q9H8M7,P63208,P45974,Q9Y314,O75592,Q93034,Q5T4S7,Q7Z6Z7,Q96FW1,Q86UV5,Q96T88,Q9UJX2,Q13263,Q5TAQ9,Q96J02,Q14139
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
128,402,664,395,264,546,392,146,18,285,661,425,423,648,300,299,519,169,171,715,178,718,450,314,312,443,185,302,442,202,439,561,605,219,352,630,634,638,494,499,115,487,490,126,533
302,1484,1766,1129,950,219,1490,648,869,2038,18,827,519,1011,561,1729,1926,312,1368,314,968,782,439,661,487,973,1109,787,1702,1591,533,442,975,1815,1075,664,2189,392,1324,264,883,630,490,443,395,634,494,715,299,2080,2005,185,300,1387,855,1290,352,638,1860,126,857,718,499,936,1160,1940,423,202,450,2014,128,2054,1119,146,989,402,115,1207,285,425,2089,1720,546,169,1038,605,171,1563,1209,178,943,727
0.730826559921213,-0.21272571549189503,-0.42583141250889395,0.027665838086341914,0.14667069399718627,0.9313443171057458,-0.21272571549189503,0.3531228099863507,0.2058875754695338,-0.6727843897556249,3.7035378773687953,0.23542606283924014,0.47010609080532134,0.11699149062391306,0.4409258805823772,-0.3952226726312979,-0.5488370384270144,0.730826559921213,-0.12219648225605645,0.730826559921213,0.14667069399718627,0.2649184437199032,0.5573891868193322,0.3531228099863507,0.4992431492624739,0.14667069399718627,0.05748948699344504,0.2649184437199032,-0.364669859579678,-0.27334151033073334,0.47010609080532134,0.5573891868193322,0.14667069399718627,-0.4564966412770062,0.087264561932277,0.3531228099863507,-0.8291051207987041,0.615366695909301,-0.09212329847709767,0.8169980768047461,0.2058875754695338,0.38243459835151017,0.4992431492624739,0.5573891868193322,0.615366695909301,0.38243459835151017,0.4992431492624739,0.3237664369124269,0.7595902108481608,-0.7039230664205183,-0.6106905307608944,1.0450797177342925,0.7595902108481608,-0.12219648225605645,0.23542606283924014,-0.06210093493456228,0.6731783026903564,0.38243459835151017,-0.4872189313453426,1.298839486996753,0.23542606283924014,0.3237664369124269,0.4992431492624739,0.17630258634391707,0.027665838086341914,-0.5488370384270144,0.5863988415320117,0.9882872661563274,0.5573891868193322,-0.6106905307608944,1.298839486996753,-0.6727843897556249,0.05748948699344504,1.2145752253051996,0.14667069399718627,0.615366695909301,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.5863988415320117,-0.7039230664205183,-0.364669859579678,0.47010609080532134,1.1017238127490079,0.11699149062391306,0.4117021682718201,1.1017238127490079,-0.24300698162028928,-0.002206819462379813,1.0734201781652684,0.17630258634391707,0.3237664369124269
2,448
Hedgehog on state
19
40
2.823299
0.004753
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q96J02,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,77,220,227,484,488,126,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,833,1728,167,77,1102,484,969,697,1503,1463,531,390,1702,488,750,397,126,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,0.23542606283924014,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,-0.364669859579678,0.4992431492624739,0.29436510731780724,0.615366695909301,1.298839486996753,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Tcr signaling
19
41
2.819523
0.00481
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,831,1650,260,1728,167,77,1102,484,782,969,697,1503,1463,439,531,626,390,1109,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,0.23542606283924014,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.2649184437199032,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.38243459835151017,0.615366695909301,0.05748948699344504,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Dna replication pre initiation
33
54
2.770891
0.00559
P48556,Q13200,P25789,P27694,P33991,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q14974,Q99436,P49642,P35998,Q07864,P51665,P15927,P33993,P62191,P09884,P20618,O43242,O14818,P60900,Q15008,P25205,Q06323,Q92530,O60684
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,655,658,291,167,581,49,51,588,54,724,550,705,69,565,691,598,77,251,592,697,464,220,227,730,484,488,738,531,397,250
550,946,1766,730,227,1913,250,1872,464,251,1003,1052,220,738,1310,291,1268,275,655,1727,54,49,51,658,1497,592,691,1650,260,565,740,1728,167,1060,77,1320,1102,484,969,697,1503,1463,2332,531,598,390,1074,705,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5488370384270144,0.8456428872388043,-0.5179988657470733,0.5283374011848795,0.8456428872388043,0.11699149062391306,0.087264561932277,0.9313443171057458,0.29436510731780724,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,0.3531228099863507,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3531228099863507,-0.21272571549189503,0.4117021682718201,0.3237664369124269,-0.33417242136584113,0.8169980768047461,0.4409258805823772,0.29436510731780724,-0.3952226726312979,1.1017238127490079,0.087264561932277,1.6880249517622525,-0.09212329847709767,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,-1.1467083845303592,0.47010609080532134,0.4117021682718201,0.615366695909301,0.087264561932277,0.3237664369124269,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Mapk family signaling cascades
36
76
2.764096
0.005708
Q92530,P04792,P48556,Q13200,Q9UQ13,P25789,Q06124,P62993,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,P35609,Q99436,P06493,P17612,P35998,P51665,P25685,P60953,Q9Y490,P20618,Q96S59,O43242,Q13177,P49354,P18206,P60900,Q15008,Q06323,P30153
Processes and pathways
Reactome Pathways
msigdb_reactome
397,6,260,390,426,275,295,293,291,167,581,49,51,588,54,724,550,434,69,683,686,691,77,208,595,361,220,498,227,626,242,614,484,488,531,618
550,946,1766,730,1401,227,1951,1616,2094,1872,6,683,686,1052,614,220,208,1310,291,1268,275,1221,1727,54,49,51,1494,775,618,961,1455,2205,434,691,1010,831,1650,964,260,242,1728,167,77,1411,1102,484,595,969,2150,697,1503,1463,293,879,786,295,531,626,390,1702,842,843,488,977,397,1117,498,69,581,1203,2168,1638,588,724,426,361
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,-0.15232095828757117,0.9028157215260153,-0.5797340545401417,-0.30372981581819986,-0.7351237916771668,-0.5179988657470733,5.931560240339164,0.3237664369124269,0.3237664369124269,0.087264561932277,0.38243459835151017,0.9313443171057458,0.9598347398148359,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.03212892744333096,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.21272571549189503,0.2649184437199032,0.38243459835151017,0.14667069399718627,-0.182497206611748,-0.8605609719945663,0.5573891868193322,0.3237664369124269,0.11699149062391306,0.23542606283924014,-0.33417242136584113,0.14667069399718627,0.8169980768047461,0.8742486728862037,-0.3952226726312979,1.1017238127490079,1.6880249517622525,-0.15232095828757117,0.05748948699344504,0.4992431492624739,0.4117021682718201,0.14667069399718627,-0.7977141188950565,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.7595902108481608,0.2058875754695338,0.2649184437199032,0.7595902108481608,0.47010609080532134,0.38243459835151017,0.615366695909301,-0.364669859579678,0.23542606283924014,0.23542606283924014,0.4992431492624739,0.14667069399718627,0.615366695909301,0.05748948699344504,0.4992431492624739,1.7705913566526543,0.4409258805823772,-0.002206819462379813,-0.7977141188950565,-0.30372981581819986,0.4409258805823772,0.3237664369124269,0.5863988415320117,0.6731783026903564
2,448
Degradation of axin
18
36
2.756399
0.005844
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Cross presentation of soluble exogenous antigens endosomes
18
36
2.756399
0.005844
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Metabolism of polyamines
18
37
2.7401
0.006142
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,1052,1534,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,-0.24300698162028928,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Regulation of runx3 expression and activity
18
37
2.734221
0.006253
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,789,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.2649184437199032,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Orc1 removal from chromatin
26
45
2.734038
0.006256
P48556,Q13200,P25789,P33991,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P63208,P35998,P51665,P33993,P62191,P20618,O43242,O14818,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,658,291,167,581,49,51,588,54,724,550,69,439,691,77,592,697,220,227,730,484,488,531,397
550,946,1766,730,227,1913,1872,1052,220,738,1310,291,1268,275,1727,54,49,51,658,1497,592,691,1650,260,1728,167,1060,77,1102,484,969,697,1503,1463,439,531,390,1109,1074,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5488370384270144,-0.5179988657470733,0.087264561932277,0.9313443171057458,0.29436510731780724,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3531228099863507,-0.21272571549189503,0.4117021682718201,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,0.087264561932277,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.47010609080532134,0.615366695909301,0.05748948699344504,0.087264561932277,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Translational initiation
23
61
2.72189
0.006491
Q92499,P04792,P60228,Q7L2H7,Q92905,P78344,O75822,Q04637,Q6PKG0,P56537,P23588,Q9Y262,P55010,Q7Z478,P55884,P05198,P60842,O15372,Q9Y5A9,Q9UI10,Q9Y6E2,Q9NR50,Q07666
Processes and pathways
GO Biological process
msigdb_gobp
672,6,387,11,673,529,147,278,576,313,173,453,62,329,327,463,594,590,236,379,643,245,532
1484,1399,996,590,1613,1444,1047,769,647,1094,1488,147,6,463,1988,1134,822,1405,1220,774,173,1269,1408,1012,1695,62,327,313,387,594,745,1413,2043,2273,529,278,1544,532,1589,1417,703,1070,974,1150,1420,844,576,751,11,329,672,673,1337,860,1340,245,1256,379,453,236,643
-0.21272571549189503,-0.15232095828757117,0.11699149062391306,0.4117021682718201,-0.30372981581819986,-0.182497206611748,0.087264561932277,0.2649184437199032,0.3531228099863507,0.05748948699344504,-0.21272571549189503,1.1864163358736073,5.931560240339164,0.5283374011848795,-0.6106905307608944,0.027665838086341914,0.23542606283924014,-0.15232095828757117,-0.03212892744333096,0.2649184437199032,1.0734201781652684,-0.06210093493456228,-0.15232095828757117,0.11699149062391306,-0.364669859579678,1.798050804303417,0.7020226932379363,0.730826559921213,0.615366695909301,0.4117021682718201,0.29436510731780724,-0.15232095828757117,-0.6727843897556249,-0.9553250615605502,0.47010609080532134,0.7883139498979853,-0.24300698162028928,0.47010609080532134,-0.27334151033073334,-0.15232095828757117,0.3237664369124269,0.087264561932277,0.14667069399718627,0.027665838086341914,-0.15232095828757117,0.23542606283924014,0.4409258805823772,0.29436510731780724,4.612142867783727,0.7020226932379363,0.3531228099863507,0.3531228099863507,-0.09212329847709767,0.23542606283924014,-0.09212329847709767,0.8742486728862037,-0.03212892744333096,0.6442930758559092,0.5573891868193322,0.9028157215260153,0.38243459835151017
2,448
Regulation of ras by gaps
18
37
2.707554
0.006778
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,1702,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,-0.364669859579678,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Degradation of dvl
18
37
2.707554
0.006778
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,1702,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,-0.364669859579678,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Translation initiation factor
11
20
2.691253
0.007118
O75153,P60228,P55884,P78344,P56537,P23588,O75822,Q9Y262,P05198,Q04637,P55010
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
9,387,327,529,313,173,147,453,463,278,62
996,1444,9,147,463,552,1220,173,62,327,313,387,1629,529,278,1070,974,844,1761,453
0.11699149062391306,-0.182497206611748,5.057346280317093,1.1864163358736073,0.5283374011848795,0.4409258805823772,-0.03212892744333096,1.0734201781652684,1.798050804303417,0.7020226932379363,0.730826559921213,0.615366695909301,-0.30372981581819986,0.47010609080532134,0.7883139498979853,0.087264561932277,0.14667069399718627,0.23542606283924014,-0.3952226726312979,0.5573891868193322
2,448
Uch proteinases
19
44
2.66534
0.007691
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,Q8NB78,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,78,77,220,227,484,488,531,397
550,946,1766,730,1129,227,1872,2110,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,1461,77,1102,484,969,697,1503,1463,531,390,488,845,78,397,69,581,588,724,1906,1209,727
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.027665838086341914,0.9028157215260153,-0.5179988657470733,-0.7663872448501347,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,-0.182497206611748,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.23542606283924014,1.6880249517622525,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269,-0.5179988657470733,-0.002206819462379813,0.3237664369124269
2,448
Cdt1 association with the cdc6 orc origin complex
18
37
2.658723
0.007844
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1913,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5488370384270144,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Proteasome degradation
17
41
2.650833
0.008029
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323
Processes and pathways
WikiPathways
msigdb_wp
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531
550,946,730,227,1872,1170,1575,1876,816,1533,1003,1052,220,827,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,488,69,581,588,724
0.4409258805823772,0.14667069399718627,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.002206819462379813,-0.27334151033073334,-0.5179988657470733,0.23542606283924014,-0.24300698162028928,0.11699149062391306,0.087264561932277,0.9313443171057458,0.23542606283924014,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Cell cell adhesion
22
73
2.62946
0.008552
Q9NYL9,Q9UQB8,Q9Y624,P04792,P04083,P61586,Q5JRA6,Q06124,Q13630,Q8WX93,P31949,P35241,Q9UDY2,O00151,P41440,P35613,Q9Y490,Q9Y5K6,Q9NUQ9,Q9Y5A9,P17931,Q96J02
Processes and pathways
GO Biological process
msigdb_gobp
401,134,405,6,15,25,28,295,161,162,414,415,46,428,71,76,361,362,235,236,368,126
428,2035,1168,1042,2139,1400,2173,1403,1681,733,2385,15,1575,6,1769,1771,653,654,2297,684,1580,432,1624,368,614,1453,1005,774,689,414,1139,913,1407,415,523,76,831,71,525,1063,744,25,2043,1845,295,1235,1377,1507,161,789,1736,2072,1631,791,749,2311,28,162,755,2193,933,580,126,2011,235,401,46,134,1983,361,236,362,405
0.5573891868193322,-0.6727843897556249,-0.002206819462379813,0.087264561932277,-0.7977141188950565,-0.15232095828757117,-0.8291051207987041,-0.15232095828757117,-0.364669859579678,0.29436510731780724,-1.504130786089521,4.161025061636598,-0.27334151033073334,5.931560240339164,-0.42583141250889395,-0.42583141250889395,0.3531228099863507,0.3531228099863507,-1.0188392846787804,0.3237664369124269,-0.27334151033073334,0.5573891868193322,-0.30372981581819986,0.6442930758559092,0.38243459835151017,-0.182497206611748,0.11699149062391306,0.2649184437199032,0.3237664369124269,0.5863988415320117,0.027665838086341914,0.17630258634391707,-0.15232095828757117,0.5863988415320117,0.47010609080532134,1.6880249517622525,0.23542606283924014,1.7431006951795138,0.47010609080532134,0.087264561932277,0.29436510731780724,2.581598099731636,-0.6727843897556249,-0.4872189313453426,0.7595902108481608,-0.03212892744333096,-0.12219648225605645,-0.21272571549189503,1.1299908805711318,0.2649184437199032,-0.3952226726312979,-0.7039230664205183,-0.30372981581819986,0.2649184437199032,0.29436510731780724,-1.0507002473854663,2.5283117833572146,1.1299908805711318,0.29436510731780724,-0.8291051207987041,0.17630258634391707,0.4409258805823772,1.298839486996753,-0.6106905307608944,0.9028157215260153,0.615366695909301,1.9621626060274844,1.2707865591544374,-0.5797340545401417,0.6731783026903564,0.9028157215260153,0.6731783026903564,0.615366695909301
2,448
Tetratricopeptide repeat [IPR019734]
12
40
2.6184
0.008834
P49321,Q6DKK2,Q13451,O76094,Q9UJX4,Q9UJX2,Q9H3U1,Q13325,Q6PD62,Q9BXJ9,O15460,Q02790
Sequence
InterPro Repeat
interpro_repeat
309,223,232,141,285,115,355,183,58,255,29,193
1041,1129,29,1615,141,1874,1449,909,553,519,521,309,1729,1411,193,840,1465,1590,703,183,232,2187,1467,1236,223,58,1425,669,935,1200,255,355,356,1392,115,1207,285,1720,1038,1869
0.087264561932277,0.027665838086341914,2.5016288793513897,-0.30372981581819986,1.2145752253051996,-0.5179988657470733,-0.182497206611748,0.17630258634391707,0.4409258805823772,0.47010609080532134,0.47010609080532134,0.730826559921213,-0.3952226726312979,-0.15232095828757117,1.0167021690167521,0.23542606283924014,-0.182497206611748,-0.27334151033073334,0.3237664369124269,1.0450797177342925,0.9028157215260153,-0.8291051207987041,-0.182497206611748,-0.03212892744333096,0.9313443171057458,1.825479230161245,-0.15232095828757117,0.3531228099863507,0.17630258634391707,-0.002206819462379813,0.8456428872388043,0.6731783026903564,0.6731783026903564,-0.12219648225605645,1.3548410508645194,-0.002206819462379813,0.7883139498979853,-0.364669859579678,0.11699149062391306,-0.4872189313453426
2,448
Asymmetric localization of pcp proteins
18
37
2.618005
0.008845
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,2072,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,-0.7039230664205183,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Nucleoside triphosphate metabolic process
6
42
2.616401
0.008886
Q9H773,Q9BZX2,Q9NRF8,P55263,P61586,O00178
Processes and pathways
GO Biological process
msigdb_gobp
0,164,79,117,25,56
56,2036,1262,1489,1096,1686,591,1724,2142,2306,1770,1451,1049,956,2113,273,773,2146,1006,2324,911,556,1222,2180,962,2300,1368,117,1142,1230,25,1017,440,536,184,1517,164,0,79,1641,1440,1127
1.825479230161245,-0.6727843897556249,-0.06210093493456228,-0.21272571549189503,0.05748948699344504,-0.364669859579678,0.4117021682718201,-0.3952226726312979,-0.7977141188950565,-1.0507002473854663,-0.42583141250889395,-0.182497206611748,0.087264561932277,0.14667069399718627,-0.7663872448501347,0.7883139498979853,0.2649184437199032,-0.7977141188950565,0.11699149062391306,-1.114634054017247,0.17630258634391707,0.4409258805823772,-0.03212892744333096,-0.8291051207987041,0.14667069399718627,-1.0188392846787804,-0.12219648225605645,1.3268575727799916,0.027665838086341914,-0.03212892744333096,2.581598099731636,0.11699149062391306,0.5573891868193322,0.47010609080532134,1.0450797177342925,-0.21272571549189503,1.1299908805711318,10.572089480261452,1.6880249517622525,-0.30372981581819986,-0.15232095828757117,0.05748948699344504
2,448
Recurrent fractures
8
26
2.613931
0.008951
Q9Y2U8,P48735,O75874,Q9UNW1,P40763,O75718,Q96AY3,Q13126
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
337,3,7,80,241,306,26,222
810,1350,306,7,651,1988,1532,2039,2019,2064,241,3,2118,1368,222,2025,1188,795,1819,1115,26,476,355,1480,80,337
0.23542606283924014,-0.12219648225605645,0.730826559921213,5.594030281929976,0.3531228099863507,-0.6106905307608944,-0.24300698162028928,-0.6727843897556249,-0.6417070956037559,-0.7039230664205183,0.8742486728862037,6.432398994236586,-0.7663872448501347,-0.12219648225605645,0.9313443171057458,-0.6417070956037559,-0.002206819462379813,0.2649184437199032,-0.4564966412770062,0.05748948699344504,2.5549681424265085,0.5283374011848795,0.6731783026903564,-0.182497206611748,1.6880249517622525,0.7020226932379363
2,448
ubiquitin-protein ligase
27
49
2.588113
0.00965
Q9NT62,Q9UBT2,Q7Z6E9,Q16763,Q15386,P19474,P68036,Q9ULT8,O94874,P30260,Q9Y4X5,Q9HB71,P61081,Q8TBC4,A0AVT1,Q99816,P63208,O75592,Q93034,Q5T4S7,Q7Z6Z7,Q96T88,Q12899,Q9UJX2,Q5TAQ9,Q96J02,Q14139
Functions
Panther Protein class
panther_protein_class
128,402,395,264,392,18,661,425,648,519,178,450,314,185,302,332,439,219,352,630,634,499,486,115,490,126,533
302,219,1490,648,869,2038,18,827,519,1011,314,968,782,439,661,486,973,1109,787,1702,1591,533,1815,392,264,883,630,490,395,634,715,2080,185,933,352,126,499,332,1940,450,128,989,402,115,1207,425,1720,1983,178
0.730826559921213,0.9313443171057458,-0.21272571549189503,0.3531228099863507,0.2058875754695338,-0.6727843897556249,3.7035378773687953,0.23542606283924014,0.47010609080532134,0.11699149062391306,0.730826559921213,0.14667069399718627,0.2649184437199032,0.5573891868193322,0.3531228099863507,0.4992431492624739,0.14667069399718627,0.05748948699344504,0.2649184437199032,-0.364669859579678,-0.27334151033073334,0.47010609080532134,-0.4564966412770062,0.615366695909301,0.8169980768047461,0.2058875754695338,0.38243459835151017,0.4992431492624739,0.615366695909301,0.38243459835151017,0.3237664369124269,-0.7039230664205183,1.0450797177342925,0.17630258634391707,0.6731783026903564,1.298839486996753,0.4992431492624739,0.7020226932379363,-0.5488370384270144,0.5573891868193322,1.298839486996753,0.14667069399718627,0.615366695909301,1.3548410508645194,-0.002206819462379813,0.5863988415320117,-0.364669859579678,-0.5797340545401417,1.0734201781652684
2,448
Tetratricopeptide-like helical domain superfamily [IPR011990]
26
72
2.581042
0.00985
O75153,O76094,Q9UJX4,Q9H7B4,O15460,P31948,P30260,Q96EK5,Q9UBV2,Q9Y262,Q13325,P61201,O75718,Q6PD62,Q96TC7,O00231,Q02790,P49321,Q9H3U1,Q9H6T3,Q6DKK2,Q13451,O43242,Q9UJX2,Q15008,Q9BXJ9
Sequence
InterPro Superfamily
interpro_homologous_superfamily
9,141,285,24,29,521,519,448,452,453,183,571,306,58,187,550,193,309,355,356,223,232,227,115,488,255
1041,550,1442,1950,1911,1129,29,227,1615,2109,9,306,141,1874,1449,909,553,519,521,1626,1408,2022,309,1729,1411,1015,571,1067,193,840,1465,1590,1658,703,183,232,2187,2073,1467,488,707,1236,795,223,58,1425,669,2006,1635,2237,448,1515,187,935,1200,2164,255,1338,355,356,24,1392,1255,452,115,1207,285,1720,453,1038,864,1869
0.087264561932277,0.4409258805823772,-0.182497206611748,-0.5797340545401417,-0.5488370384270144,0.027665838086341914,2.5016288793513897,0.9028157215260153,-0.30372981581819986,-0.7663872448501347,5.057346280317093,0.730826559921213,1.2145752253051996,-0.5179988657470733,-0.182497206611748,0.17630258634391707,0.4409258805823772,0.47010609080532134,0.47010609080532134,-0.30372981581819986,-0.15232095828757117,-0.6417070956037559,0.730826559921213,-0.3952226726312979,-0.15232095828757117,0.11699149062391306,0.4409258805823772,0.087264561932277,1.0167021690167521,0.23542606283924014,-0.182497206611748,-0.27334151033073334,-0.33417242136584113,0.3237664369124269,1.0450797177342925,0.9028157215260153,-0.8291051207987041,-0.7039230664205183,-0.182497206611748,0.4992431492624739,0.3237664369124269,-0.03212892744333096,0.2649184437199032,0.9313443171057458,1.825479230161245,-0.15232095828757117,0.3531228099863507,-0.6106905307608944,-0.30372981581819986,-0.8920824087947153,0.5573891868193322,-0.21272571549189503,1.0450797177342925,0.17630258634391707,-0.002206819462379813,-0.7977141188950565,0.8456428872388043,-0.09212329847709767,0.6731783026903564,0.6731783026903564,2.7408312506583243,-0.12219648225605645,-0.03212892744333096,0.5573891868193322,1.3548410508645194,-0.002206819462379813,0.7883139498979853,-0.364669859579678,0.5573891868193322,0.11699149062391306,0.23542606283924014,-0.4872189313453426
2,448
Ubiquitin like protein transferase activity
26
45
2.574609
0.010035
Q9NT62,Q7Z6E9,Q16763,Q9UPN9,Q15386,P19474,P68036,Q9ULT8,Q9Y3C8,Q9Y4X5,P61081,Q5VTR2,Q8TBC4,Q14258,Q9Y314,P60953,O75592,Q93034,Q5T4S7,Q7Z6Z7,Q96T88,Q12899,Q9UJX2,Q13263,Q96J02,Q14139
Functions
GO Molecular function
msigdb_gomf
128,395,264,546,392,18,661,425,171,178,314,443,185,442,605,595,219,352,630,634,499,486,115,487,126,533
950,219,1490,648,869,2038,18,1011,1729,595,314,968,782,661,486,487,1702,533,442,975,1815,392,264,883,630,443,395,634,2080,185,352,126,499,1160,2014,128,115,425,2089,1720,546,605,171,178,943
0.14667069399718627,0.9313443171057458,-0.21272571549189503,0.3531228099863507,0.2058875754695338,-0.6727843897556249,3.7035378773687953,0.11699149062391306,-0.3952226726312979,0.4117021682718201,0.730826559921213,0.14667069399718627,0.2649184437199032,0.3531228099863507,0.4992431492624739,0.4992431492624739,-0.364669859579678,0.47010609080532134,0.5573891868193322,0.14667069399718627,-0.4564966412770062,0.615366695909301,0.8169980768047461,0.2058875754695338,0.38243459835151017,0.5573891868193322,0.615366695909301,0.38243459835151017,-0.7039230664205183,1.0450797177342925,0.6731783026903564,1.298839486996753,0.4992431492624739,0.027665838086341914,-0.6106905307608944,1.298839486996753,1.3548410508645194,0.5863988415320117,-0.7039230664205183,-0.364669859579678,0.47010609080532134,0.4117021682718201,1.1017238127490079,1.0734201781652684,0.17630258634391707
2,448
Abc family proteins mediated transport
21
46
2.572044
0.01011
P48556,Q13200,Q9BUN8,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q99436,P51665,P05198,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,159,275,291,167,581,49,51,452,588,54,69,77,463,220,227,484,488,531,397
550,946,1766,730,227,2319,1872,2017,463,1990,1052,1220,220,1310,291,1268,275,1727,54,49,51,1536,691,1650,260,1728,167,77,1102,1368,484,969,697,1503,1463,531,390,488,1241,397,69,581,159,452,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-1.114634054017247,-0.5179988657470733,-0.6417070956037559,0.5283374011848795,-0.6106905307608944,0.087264561932277,-0.03212892744333096,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.24300698162028928,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,-0.12219648225605645,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,-0.03212892744333096,0.615366695909301,1.7705913566526543,0.4409258805823772,1.1582216374253231,0.5573891868193322,0.4409258805823772,0.3237664369124269
2,448
Proteasome, subunit alpha/beta [IPR001353]
7
14
2.566944
0.01026
Q99436,P49721,P28072,P28074,P28070,P25789,P20618
Sequence
InterPro Family
interpro_family
69,167,49,51,54,275,220
730,220,1310,291,1268,275,1727,54,49,51,1728,167,484,69
0.29436510731780724,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.3952226726312979,1.1017238127490079,0.4992431492624739,1.7705913566526543
2,448
Cellular response to hypoxia
18
38
2.566296
0.010279
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,787,488,2189,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.2649184437199032,0.4992431492624739,-0.8291051207987041,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Runx1 regulates transcription of genes involved in differentiation of hscs
19
41
2.565526
0.010302
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,P20618,O43242,P60900,Q15008,Q96J02,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,77,220,227,484,488,126,531,397
550,946,1766,730,227,1872,1003,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,2332,2024,531,390,789,488,397,126,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.11699149062391306,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,-1.1467083845303592,-0.6417070956037559,0.47010609080532134,0.615366695909301,0.2649184437199032,0.4992431492624739,0.615366695909301,1.298839486996753,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Protein modification by small protein conjugation or removal
72
160
2.565113
0.010314
Q9NT62,Q9UBT2,Q15018,Q9UNS2,Q7Z6E9,Q16763,Q9UPN9,P48506,Q15386,Q92905,Q9NXR7,P19474,Q9UJX4,P68036,Q9BUN8,Q9ULT8,Q9H4L4,O75340,O94874,Q8TEY7,Q86WB0,P30260,Q13155,Q9Y3C8,Q6DKJ4,Q86VP6,Q9Y4X5,Q13526,Q96MG7,Q9Y5K5,Q9UBV2,P61081,P61201,Q6PD62,Q8TBC4,A0AVT1,Q5VTR2,P61927,Q14258,Q15020,P31689,Q9H8M7,Q99816,P63208,Q9UBW8,P45974,Q9Y314,Q9UBV8,Q9NW82,Q9UIQ6,P60953,O60678,O75592,Q93034,Q5T4S7,Q99627,Q7Z6Z7,Q13867,Q96FW1,Q86UV5,Q96T88,Q04323,Q12899,Q9UJX2,Q00535,P46777,Q13263,P55786,Q5TAQ9,Q9NVI1,Q96J02,Q14139
Processes and pathways
GO Biological process
msigdb_gobp
128,402,664,404,395,264,546,385,392,673,146,18,285,661,159,425,423,160,648,300,299,519,573,171,575,715,178,175,718,727,452,314,571,58,185,302,443,192,442,707,558,202,332,439,75,561,605,604,216,87,595,218,219,352,630,224,634,347,638,494,499,111,486,115,370,369,487,118,490,400,126,533
302,1484,1766,1399,1129,768,1486,1571,218,950,160,219,1872,1490,648,869,683,1002,1172,1097,2038,1306,18,827,774,1992,1454,519,558,1363,1407,1011,561,1694,369,385,1729,915,1585,1926,1368,118,1541,595,314,968,782,571,192,1371,1628,1415,439,1066,661,370,111,486,701,573,487,1659,2025,175,973,1109,787,1702,1591,347,789,533,442,975,1815,1075,664,707,2157,2189,392,2214,1324,264,794,1853,883,630,490,443,575,750,58,1593,395,634,494,715,299,1551,2080,185,300,673,933,855,1290,352,638,1860,126,1198,857,718,499,2303,224,332,1159,159,2010,2011,1160,937,1940,423,202,2014,128,1119,400,1520,216,146,1830,2169,989,402,452,604,75,1122,87,115,1207,285,425,2089,1720,404,546,605,171,2380,1563,1209,178,943,864,727
0.730826559921213,-0.21272571549189503,-0.42583141250889395,-0.15232095828757117,0.027665838086341914,0.2649184437199032,-0.21272571549189503,-0.27334151033073334,0.9313443171057458,0.14667069399718627,1.1299908805711318,0.9313443171057458,-0.5179988657470733,-0.21272571549189503,0.3531228099863507,0.2058875754695338,0.3237664369124269,0.11699149062391306,-0.002206819462379813,0.05748948699344504,-0.6727843897556249,-0.09212329847709767,3.7035378773687953,0.23542606283924014,0.2649184437199032,-0.6106905307608944,-0.182497206611748,0.47010609080532134,0.4409258805823772,-0.12219648225605645,-0.15232095828757117,0.11699149062391306,0.4409258805823772,-0.364669859579678,0.6442930758559092,0.615366695909301,-0.3952226726312979,0.17630258634391707,-0.27334151033073334,-0.5488370384270144,-0.12219648225605645,1.3268575727799916,-0.24300698162028928,0.4117021682718201,0.730826559921213,0.14667069399718627,0.2649184437199032,0.4409258805823772,1.0167021690167521,-0.12219648225605645,-0.30372981581819986,-0.15232095828757117,0.5573891868193322,0.087264561932277,0.3531228099863507,0.6442930758559092,1.3548410508645194,0.4992431492624739,0.3237664369124269,0.4409258805823772,0.4992431492624739,-0.33417242136584113,-0.6417070956037559,1.0734201781652684,0.14667069399718627,0.05748948699344504,0.2649184437199032,-0.364669859579678,-0.27334151033073334,0.6731783026903564,0.2649184437199032,0.47010609080532134,0.5573891868193322,0.14667069399718627,-0.4564966412770062,0.087264561932277,0.3531228099863507,0.3237664369124269,-0.7977141188950565,-0.8291051207987041,0.615366695909301,-0.8605609719945663,-0.09212329847709767,0.8169980768047461,0.2649184437199032,-0.4872189313453426,0.2058875754695338,0.38243459835151017,0.4992431492624739,0.5573891868193322,0.4409258805823772,0.29436510731780724,1.825479230161245,-0.27334151033073334,0.615366695909301,0.38243459835151017,0.4992431492624739,0.3237664369124269,0.7595902108481608,-0.24300698162028928,-0.7039230664205183,1.0450797177342925,0.7595902108481608,0.3531228099863507,0.17630258634391707,0.23542606283924014,-0.06210093493456228,0.6731783026903564,0.38243459835151017,-0.4872189313453426,1.298839486996753,-0.002206819462379813,0.23542606283924014,0.3237664369124269,0.4992431492624739,-1.0188392846787804,0.9313443171057458,0.7020226932379363,0.027665838086341914,1.1582216374253231,-0.6106905307608944,-0.6106905307608944,0.027665838086341914,0.17630258634391707,-0.5488370384270144,0.5863988415320117,0.9882872661563274,-0.6106905307608944,1.298839486996753,0.05748948699344504,0.615366695909301,-0.21272571549189503,0.9598347398148359,1.2145752253051996,-0.4564966412770062,-0.7977141188950565,0.14667069399718627,0.615366695909301,0.5573891868193322,0.4117021682718201,1.7155786256844825,0.05748948699344504,1.5497754824846934,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.5863988415320117,-0.7039230664205183,-0.364669859579678,0.615366695909301,0.47010609080532134,0.4117021682718201,1.1017238127490079,-1.4058330257519098,-0.24300698162028928,-0.002206819462379813,1.0734201781652684,0.17630258634391707,0.23542606283924014,0.3237664369124269
2,448
Signaling
6
15
2.55455
0.010633
Q99627,Q8WUJ1,P51858,P43490,Q5JRA6,Q7Z4V5
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
224,1,199,17,28,350
1211,1800,1680,368,1774,17,199,485,1813,28,350,1472,1,224,1122
-0.03212892744333096,-0.4564966412770062,-0.364669859579678,0.6442930758559092,-0.42583141250889395,3.856772038666039,0.9882872661563274,0.4992431492624739,-0.4564966412770062,2.5283117833572146,0.6731783026903564,-0.182497206611748,8.218958800035029,0.9313443171057458,0.05748948699344504
2,448
Stabilization of p53
18
38
2.532497
0.011325
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,1684,2203,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.364669859579678,-0.8605609719945663,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
G1 s dna damage checkpoints
18
38
2.532497
0.011325
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,1684,2203,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,390,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.364669859579678,-0.8605609719945663,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Threonine type peptidase activity
7
10
2.524524
0.011586
Q99436,Q9UJ14,P49721,P28072,P28074,P28070,P20618
Functions
GO Molecular function
msigdb_gomf
69,271,167,49,51,54,220
220,275,54,49,51,1728,167,2078,69,271
0.9313443171057458,0.7883139498979853,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.3952226726312979,1.1017238127490079,-0.7039230664205183,1.7705913566526543,0.8169980768047461
2,448
translation initiation factor
15
41
2.52429
0.011593
O75153,P60228,P55884,Q9UI10,P78344,P56537,P51665,P23588,Q9NR50,O75822,Q9Y262,P05198,Q04637,P55010,P06730
Functions
Panther Protein class
panther_protein_class
9,387,327,379,529,313,77,173,245,147,453,463,278,62,552
1484,1766,996,590,1444,1047,769,9,1488,147,463,552,1220,173,1367,1695,77,62,327,313,387,1629,529,1588,278,1417,1070,974,1150,844,2003,1593,1154,673,860,245,1256,379,1761,453,726
-0.21272571549189503,-0.42583141250889395,0.11699149062391306,0.4117021682718201,-0.182497206611748,0.087264561932277,0.2649184437199032,5.057346280317093,-0.21272571549189503,1.1864163358736073,0.5283374011848795,0.4409258805823772,-0.03212892744333096,1.0734201781652684,-0.12219648225605645,-0.364669859579678,1.6880249517622525,1.798050804303417,0.7020226932379363,0.730826559921213,0.615366695909301,-0.30372981581819986,0.47010609080532134,-0.27334151033073334,0.7883139498979853,-0.15232095828757117,0.087264561932277,0.14667069399718627,0.027665838086341914,0.23542606283924014,-0.6106905307608944,-0.27334151033073334,0.027665838086341914,0.3531228099863507,0.23542606283924014,0.8742486728862037,-0.03212892744333096,0.6442930758559092,-0.3952226726312979,0.5573891868193322,0.3237664369124269
2,448
Regulation of pten stability and activity
18
40
2.522477
0.011653
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,2038,1052,1582,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,1698,531,390,488,397,69,581,588,1720,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.6727843897556249,0.087264561932277,-0.27334151033073334,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,-0.364669859579678,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,-0.364669859579678,0.3237664369124269
2,448
Proteasome component (PCI) domain [IPR000717]
10
17
2.521029
0.011701
Q99627,Q9UNS2,P60228,Q9UBW8,O43242,P48556,Q7L2H7,Q9Y262,Q15008,P61201
Sequence
InterPro Domain
interpro_domain
224,404,387,75,227,260,11,453,488,571
550,946,227,260,387,571,701,974,488,11,224,1159,1256,75,724,404,453
0.4409258805823772,0.14667069399718627,0.9028157215260153,0.8169980768047461,0.615366695909301,0.4409258805823772,0.3237664369124269,0.14667069399718627,0.4992431492624739,4.612142867783727,0.9313443171057458,0.027665838086341914,-0.03212892744333096,1.7155786256844825,0.3237664369124269,0.615366695909301,0.5573891868193322
2,448
Ubiquitin ligase complex
19
43
2.511129
0.012035
Q9NT62,Q16763,Q9NXR7,Q9UJX4,Q9BUN8,Q9NXV2,O75340,Q8TEY7,P30260,Q9Y4X5,Q9HB71,Q9UBV2,Q5VTR2,P63208,Q93034,Q96S59,Q9UJX2,Q5TAQ9,Q14139
Localization
GO Cellular component
msigdb_gocc
128,264,146,285,159,31,160,300,519,178,450,452,443,439,352,498,115,490,533
1571,950,160,519,1011,782,439,661,1109,787,1702,1591,533,2189,1324,264,490,443,715,300,933,352,857,1117,498,159,1940,1477,450,128,1119,146,31,452,604,115,1207,285,1720,1038,1563,178,1798
-0.27334151033073334,0.14667069399718627,1.1299908805711318,0.47010609080532134,0.11699149062391306,0.2649184437199032,0.5573891868193322,0.3531228099863507,0.05748948699344504,0.2649184437199032,-0.364669859579678,-0.27334151033073334,0.47010609080532134,-0.8291051207987041,-0.09212329847709767,0.8169980768047461,0.4992431492624739,0.5573891868193322,0.3237664369124269,0.7595902108481608,0.17630258634391707,0.6731783026903564,0.23542606283924014,0.05748948699344504,0.4992431492624739,1.1582216374253231,-0.5488370384270144,-0.182497206611748,0.5573891868193322,1.298839486996753,0.05748948699344504,1.2145752253051996,2.5016288793513897,0.5573891868193322,0.4117021682718201,1.3548410508645194,-0.002206819462379813,0.7883139498979853,-0.364669859579678,0.11699149062391306,-0.24300698162028928,1.0734201781652684,-0.42583141250889395
2,448
Adaptive immune system
69
149
2.499617
0.012433
Q92530,Q7Z6E9,Q16763,P30153,Q14203,P48556,Q15386,Q9Y6G9,P19474,Q9UJX4,Q13200,P68036,Q9ULT8,P25789,P33176,Q06124,O94874,P09429,P30260,P62993,P25787,P49721,Q99460,P28072,P28074,Q9UJW0,Q9UL46,P28070,P61081,Q8TBC4,Q9UNM6,P53680,A0AVT1,O00231,O43237,P52732,Q99436,O95486,P17612,P63208,P35998,Q10567,P51665,O75935,Q9BUF5,P68371,P63104,P60953,Q9BXS5,Q9UIQ6,P62191,P50570,P20618,Q5T4S7,Q93034,O43747,Q13409,Q7Z6Z7,Q13867,O43242,Q13177,Q9UJX2,P60900,Q15008,P55786,Q15436,Q06323,Q96J02,Q14139
Processes and pathways
Reactome Pathways
msigdb_reactome
397,395,264,618,262,260,392,286,18,285,390,661,425,275,522,295,648,653,519,293,291,167,581,49,51,587,588,54,314,185,724,567,302,550,551,310,69,682,686,439,691,700,77,681,354,699,698,595,90,87,697,469,220,630,352,459,231,634,347,227,626,115,484,488,118,123,531,126,533
302,1483,1210,550,946,1766,730,551,227,459,1572,1872,681,1490,648,999,1215,1768,1216,682,1836,1170,1575,1769,653,955,1533,2387,686,1052,18,220,827,1310,291,1268,275,1137,1361,1727,54,49,51,1454,2269,618,961,519,1455,522,691,831,1408,1650,1627,1180,260,1728,167,469,1995,2286,77,310,915,916,567,1229,1102,118,1996,484,595,314,968,782,836,969,970,697,1503,1463,293,1278,698,2361,439,661,699,1067,2154,295,531,840,700,626,390,231,1071,1109,787,1702,347,2211,533,262,881,1815,843,1379,488,2189,392,123,264,2230,883,630,395,634,754,185,397,933,352,1514,126,69,581,2217,1713,354,2351,90,1160,1558,1940,87,587,115,1207,285,588,425,1720,724,1563,943,286
0.730826559921213,-0.21272571549189503,-0.03212892744333096,0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.4409258805823772,0.9028157215260153,0.5283374011848795,-0.27334151033073334,-0.5179988657470733,0.3237664369124269,-0.21272571549189503,0.3531228099863507,0.11699149062391306,-0.03212892744333096,-0.42583141250889395,-0.03212892744333096,0.3237664369124269,-0.4872189313453426,-0.002206819462379813,-0.27334151033073334,-0.42583141250889395,0.3531228099863507,0.14667069399718627,-0.24300698162028928,-1.504130786089521,0.3237664369124269,0.087264561932277,3.7035378773687953,0.9313443171057458,0.23542606283924014,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,0.027665838086341914,-0.12219648225605645,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.182497206611748,-0.9553250615605502,0.38243459835151017,0.14667069399718627,0.47010609080532134,-0.182497206611748,0.47010609080532134,0.3237664369124269,0.23542606283924014,-0.15232095828757117,-0.33417242136584113,-0.30372981581819986,-0.002206819462379813,0.8169980768047461,-0.3952226726312979,1.1017238127490079,0.5283374011848795,-0.6106905307608944,-0.987047828674115,1.6880249517622525,0.730826559921213,0.17630258634391707,0.17630258634391707,0.4409258805823772,-0.03212892744333096,0.05748948699344504,1.3268575727799916,-0.6106905307608944,0.4992431492624739,0.4117021682718201,0.730826559921213,0.14667069399718627,0.2649184437199032,0.23542606283924014,0.14667069399718627,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.7595902108481608,-0.06210093493456228,0.3237664369124269,-1.2757154640498929,0.5573891868193322,0.3531228099863507,0.3237664369124269,0.087264561932277,-0.7977141188950565,0.7595902108481608,0.47010609080532134,0.23542606283924014,0.3237664369124269,0.38243459835151017,0.615366695909301,0.9028157215260153,0.087264561932277,0.05748948699344504,0.2649184437199032,-0.364669859579678,0.6731783026903564,-0.8605609719945663,0.47010609080532134,0.8169980768047461,0.2058875754695338,-0.4564966412770062,0.23542606283924014,-0.12219648225605645,0.4992431492624739,-0.8291051207987041,0.615366695909301,1.298839486996753,0.8169980768047461,-0.8920824087947153,0.2058875754695338,0.38243459835151017,0.615366695909301,0.38243459835151017,0.29436510731780724,1.0450797177342925,0.615366695909301,0.17630258634391707,0.6731783026903564,-0.21272571549189503,1.298839486996753,1.7705913566526543,0.4409258805823772,-0.8605609719945663,-0.364669859579678,0.6731783026903564,-1.211071046856623,1.522027929261891,0.027665838086341914,-0.24300698162028928,-0.5488370384270144,1.5497754824846934,0.4409258805823772,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.5863988415320117,-0.364669859579678,0.3237664369124269,-0.24300698162028928,0.17630258634391707,0.7883139498979853
2,448
Antigen processing cross presentation
19
47
2.495215
0.012588
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P51665,Q9UIQ6,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,77,87,220,227,484,488,531,397
1210,550,946,1766,730,227,1572,1872,1170,1575,653,1533,1052,220,1310,291,1268,275,1137,1727,54,49,51,2269,691,1650,260,1728,167,77,1102,1996,484,969,970,697,1503,1463,531,390,488,397,69,581,87,588,724
-0.03212892744333096,0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.27334151033073334,-0.5179988657470733,-0.002206819462379813,-0.27334151033073334,0.3531228099863507,-0.24300698162028928,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,0.027665838086341914,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.9553250615605502,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,-0.6106905307608944,0.4992431492624739,0.14667069399718627,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,0.615366695909301,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,1.5497754824846934,0.4409258805823772,0.3237664369124269
2,448
Proteasome core complex
8
15
2.491462
0.012722
Q99436,P25787,P49721,P28072,P28074,P28070,P25789,P20618
Localization
GO Cellular component
msigdb_gocc
69,291,167,49,51,54,275,220
730,220,1310,291,1268,275,1727,54,49,51,1728,167,484,397,69
0.29436510731780724,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.3952226726312979,1.1017238127490079,0.4992431492624739,0.615366695909301,1.7705913566526543
2,448
Proteasome beta-type subunit, conserved site [IPR016050]
6
8
2.490906
0.012742
Q99436,P49721,P28072,P28074,P28070,P20618
Sequence
InterPro Conserved site
interpro_conserved_site
69,167,49,51,54,220
220,275,54,49,51,1728,167,69
0.9313443171057458,0.7883139498979853,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.3952226726312979,1.1017238127490079,1.7705913566526543
2,448
Threonine type endopeptidase activity
6
8
2.490906
0.012742
Q99436,P49721,P28072,P28074,P28070,P20618
Functions
GO Molecular function
msigdb_gomf
69,167,49,51,54,220
220,275,54,49,51,1728,167,69
0.9313443171057458,0.7883139498979853,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.3952226726312979,1.1017238127490079,1.7705913566526543
2,448
Hedgehog off state
27
48
2.466094
0.01366
Q92530,P48556,Q13200,P25789,P10644,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P17612,P63208,P35998,P51665,Q9BUF5,P68371,P20618,O43242,P60900,Q15008,Q06323,Q96J02
Processes and pathways
Reactome Pathways
msigdb_reactome
397,260,390,275,654,291,167,581,49,51,588,54,724,550,69,686,439,691,77,354,699,220,227,484,488,531,126
550,946,1766,730,227,1872,654,1623,686,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,833,1728,167,1318,77,1102,484,969,697,1503,1463,439,699,531,390,1109,2211,488,397,126,69,581,354,2351,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.3531228099863507,-0.30372981581819986,0.3237664369124269,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,0.23542606283924014,-0.3952226726312979,1.1017238127490079,-0.09212329847709767,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.3237664369124269,0.47010609080532134,0.615366695909301,0.05748948699344504,-0.8605609719945663,0.4992431492624739,0.615366695909301,1.298839486996753,1.7705913566526543,0.4409258805823772,0.6731783026903564,-1.211071046856623,0.4409258805823772,0.3237664369124269
2,448
Regulation of hmox1 expression and activity
19
43
2.463675
0.013752
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,2144,1052,1582,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,439,1698,531,390,1109,1702,488,1969,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.7977141188950565,0.087264561932277,-0.27334151033073334,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,-0.364669859579678,0.47010609080532134,0.615366695909301,0.05748948699344504,-0.364669859579678,0.4992431492624739,-0.5797340545401417,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Signaling by hedgehog
30
53
2.450184
0.014278
Q92530,P48556,Q13200,P25789,P10644,P25787,P49721,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P17612,P63208,P35998,P51665,Q9BUF5,P68371,P62191,Q6P1J9,P20618,O43242,P60900,Q15008,Q06323,Q96J02
Processes and pathways
Reactome Pathways
msigdb_reactome
397,260,390,275,654,291,167,581,49,51,452,588,54,724,550,69,686,439,691,77,354,699,697,750,220,227,484,488,531,126
550,946,1766,730,227,1872,1532,654,1623,686,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,833,1728,167,1318,77,1102,1368,484,969,697,1503,1463,439,699,531,390,1109,1702,2211,488,750,397,126,69,581,354,2351,452,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.24300698162028928,0.3531228099863507,-0.30372981581819986,0.3237664369124269,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,0.23542606283924014,-0.3952226726312979,1.1017238127490079,-0.09212329847709767,1.6880249517622525,0.05748948699344504,-0.12219648225605645,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.3237664369124269,0.47010609080532134,0.615366695909301,0.05748948699344504,-0.364669859579678,-0.8605609719945663,0.4992431492624739,0.29436510731780724,0.615366695909301,1.298839486996753,1.7705913566526543,0.4409258805823772,0.6731783026903564,-1.211071046856623,0.5573891868193322,0.4409258805823772,0.3237664369124269
2,448
Negative regulation of protein modification process
25
100
2.447087
0.014402
P04792,P48506,P19474,Q12824,Q9H7B4,Q04637,P23381,Q01105,Q13363,O43768,Q15257,O75718,P61927,P61964,Q99816,O60678,Q96B36,P11413,Q13148,O95684,Q04323,P17931,P0DP25,Q00535,P46777
Processes and pathways
GO Biological process
msigdb_gobp
6,385,18,417,24,278,274,154,32,407,55,306,192,67,332,218,100,342,346,228,111,368,240,370,369
606,1129,768,407,408,1486,1571,218,1952,306,1835,648,869,511,228,2369,6,734,1988,1097,240,654,342,1623,2038,368,2040,1492,18,274,774,1099,1992,618,558,1455,1407,1011,1776,369,1459,385,1318,525,1585,2070,1842,1541,192,67,783,1371,1586,1628,1415,1066,1416,370,154,111,278,485,417,1812,346,626,703,32,1507,2025,704,2187,1815,665,55,1469,795,575,1114,1289,933,100,638,2052,1198,674,2134,2303,332,1292,2011,24,1520,895,2137,1122,1297,1299,1608,1866
0.38243459835151017,0.027665838086341914,0.2649184437199032,0.5863988415320117,0.5863988415320117,-0.21272571549189503,-0.27334151033073334,0.9313443171057458,-0.5797340545401417,0.730826559921213,-0.4872189313453426,0.3531228099863507,0.2058875754695338,0.47010609080532134,0.9028157215260153,-1.3406374671292853,5.931560240339164,0.29436510731780724,-0.6106905307608944,0.05748948699344504,0.8742486728862037,0.3531228099863507,0.6731783026903564,-0.30372981581819986,-0.6727843897556249,0.6442930758559092,-0.6727843897556249,-0.21272571549189503,3.7035378773687953,0.7883139498979853,0.2649184437199032,0.05748948699344504,-0.6106905307608944,0.38243459835151017,0.4409258805823772,-0.182497206611748,-0.15232095828757117,0.11699149062391306,-0.42583141250889395,0.6442930758559092,-0.182497206611748,0.615366695909301,-0.09212329847709767,0.47010609080532134,-0.27334151033073334,-0.7039230664205183,-0.4872189313453426,-0.24300698162028928,1.0167021690167521,1.7705913566526543,0.2649184437199032,-0.12219648225605645,-0.27334151033073334,-0.30372981581819986,-0.15232095828757117,0.087264561932277,-0.15232095828757117,0.6442930758559092,1.1582216374253231,1.3548410508645194,0.7883139498979853,0.4992431492624739,0.5863988415320117,-0.4564966412770062,0.6731783026903564,0.38243459835151017,0.3237664369124269,2.474919285820168,-0.21272571549189503,-0.6417070956037559,0.3237664369124269,-0.8291051207987041,-0.4564966412770062,0.3531228099863507,1.8528768241204838,-0.182497206611748,0.2649184437199032,0.4409258805823772,0.05748948699344504,-0.06210093493456228,0.17630258634391707,1.4385861401124023,0.38243459835151017,-0.6727843897556249,-0.002206819462379813,0.3531228099863507,-0.7663872448501347,-1.0188392846787804,0.7020226932379363,-0.06210093493456228,-0.6106905307608944,2.7408312506583243,-0.21272571549189503,0.2058875754695338,-0.7663872448501347,0.05748948699344504,-0.06210093493456228,-0.06210093493456228,-0.27334151033073334,-0.4872189313453426
2,448
Actin cytoskeleton reorganization
13
21
2.429549
0.015118
P35579,P15311,Q9UQB8,Q9Y624,P62993,Q14247,P52565,P04083,O14786,Q00535,Q9Y5K6,P61586,P11233
Processes and pathways
GO Biological process
msigdb_gobp
523,432,134,405,293,574,326,15,508,370,362,25,517
508,15,517,432,2040,1005,523,326,595,25,293,370,1235,1781,841,574,665,1789,134,362,405
0.47010609080532134,4.161025061636598,0.47010609080532134,0.5573891868193322,-0.6727843897556249,0.11699149062391306,0.47010609080532134,0.7020226932379363,0.4117021682718201,2.581598099731636,0.7595902108481608,0.6442930758559092,-0.03212892744333096,-0.42583141250889395,0.23542606283924014,0.4409258805823772,0.3531228099863507,-0.42583141250889395,1.2707865591544374,0.6731783026903564,0.615366695909301
2,448
Signaling by notch4
19
42
2.424648
0.015323
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,69,439,77,220,227,484,488,531,397
550,946,1766,730,227,1872,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,698,439,531,2354,390,1378,1109,488,397,2163,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.3237664369124269,0.5573891868193322,0.47010609080532134,-1.243358299991923,0.615366695909301,-0.12219648225605645,0.05748948699344504,0.4992431492624739,0.615366695909301,-0.7977141188950565,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Cell projection assembly
27
69
2.413999
0.015779
Q9NT62,Q14203,O14786,O15144,P11233,A6NIH7,Q15555,P35241,Q8NCA5,Q9NQW6,Q9NR77,Q8TC07,P35609,P15311,P18085,P51116,Q9H4M9,Q9H223,Q9UBB4,P50570,O14745,Q9P258,Q9Y5K6,P27695,P20339,O00471,Q15691
Processes and pathways
GO Biological process
msigdb_gobp
128,262,508,509,517,36,296,415,447,320,59,186,434,432,433,436,333,214,479,469,207,360,362,344,230,110,112
36,110,2139,207,508,509,1835,1001,1769,1048,736,517,432,433,614,230,1005,344,912,2021,415,434,1583,1408,1180,1318,1100,469,779,436,595,1963,1880,1183,1882,2361,1587,1544,1147,1507,262,574,1422,296,112,977,1027,979,1028,670,447,186,1115,797,985,1900,214,333,320,59,128,360,479,763,1297,2265,808,1609,362
2.314092963919821,1.3548410508645194,-0.7977141188950565,0.9598347398148359,0.47010609080532134,0.47010609080532134,-0.4872189313453426,0.11699149062391306,-0.42583141250889395,0.087264561932277,0.29436510731780724,0.47010609080532134,0.5573891868193322,0.5573891868193322,0.38243459835151017,0.9028157215260153,0.11699149062391306,0.6731783026903564,0.17630258634391707,-0.6417070956037559,0.5863988415320117,0.5573891868193322,-0.27334151033073334,-0.15232095828757117,-0.002206819462379813,-0.09212329847709767,0.05748948699344504,0.5283374011848795,0.2649184437199032,0.5573891868193322,0.4117021682718201,-0.5797340545401417,-0.5179988657470733,-0.002206819462379813,-0.5179988657470733,-1.2757154640498929,-0.27334151033073334,-0.24300698162028928,0.027665838086341914,-0.21272571549189503,0.8169980768047461,0.4409258805823772,-0.15232095828757117,0.7595902108481608,1.3548410508645194,0.14667069399718627,0.11699149062391306,0.14667069399718627,0.11699149062391306,0.3531228099863507,0.5573891868193322,1.0450797177342925,0.05748948699344504,0.2649184437199032,0.14667069399718627,-0.5179988657470733,0.9598347398148359,0.7020226932379363,0.730826559921213,1.825479230161245,1.298839486996753,0.6731783026903564,0.5283374011848795,0.29436510731780724,-0.06210093493456228,-0.9236701828387313,0.2649184437199032,-0.27334151033073334,0.6731783026903564
2,448
Response to wounding
18
58
2.403693
0.01623
O43633,Q9Y624,P04792,Q99439,Q13247,Q99707,P11047,P04179,P04083,P38435,Q13310,Q00535,Q9Y490,P61586,Q96AY3,Q92766,Q5JRA6,Q96G23
Processes and pathways
GO Biological process
msigdb_gobp
130,405,6,39,73,168,229,142,15,180,371,370,361,25,26,351,28,93
2035,1168,1042,1833,2091,130,383,15,142,6,1769,683,1578,2144,229,684,1624,614,1005,1139,913,523,180,1408,2414,1226,1694,564,437,780,25,370,786,1019,485,73,1781,371,2072,2212,665,2311,28,752,2397,351,2081,26,2052,93,39,2280,168,1752,1521,2264,361,405
-0.6727843897556249,-0.002206819462379813,0.087264561932277,-0.4872189313453426,-0.7351237916771668,1.2707865591544374,0.615366695909301,4.161025061636598,1.2145752253051996,5.931560240339164,-0.42583141250889395,0.3237664369124269,-0.27334151033073334,-0.7977141188950565,0.9028157215260153,0.3237664369124269,-0.30372981581819986,0.38243459835151017,0.11699149062391306,0.027665838086341914,0.17630258634391707,0.47010609080532134,1.0450797177342925,-0.15232095828757117,-2.105990413747261,-0.03212892744333096,-0.364669859579678,0.4409258805823772,0.5573891868193322,0.2649184437199032,2.581598099731636,0.6442930758559092,0.2649184437199032,0.11699149062391306,0.4992431492624739,1.7431006951795138,-0.42583141250889395,0.6442930758559092,-0.7039230664205183,-0.8605609719945663,0.3531228099863507,-1.0507002473854663,2.5283117833572146,0.29436510731780724,-1.603022665769443,0.6731783026903564,-0.7039230664205183,2.5549681424265085,-0.6727843897556249,1.4942473318432876,2.1251973259084997,-0.9553250615605502,1.1017238127490079,-0.3952226726312979,-0.21272571549189503,-0.9236701828387313,0.6731783026903564,0.615366695909301
2,448
Translation preinitiation complex
7
15
2.393043
0.016709
P60228,Q7Z478,Q7L2H7,P55884,P56537,O75822,Q9Y262
Localization
GO Cellular component
msigdb_gocc
387,329,11,327,313,147,453
1484,996,590,1488,147,463,327,313,387,1070,974,11,329,1256,453
-0.21272571549189503,0.11699149062391306,0.4117021682718201,-0.21272571549189503,1.1864163358736073,0.5283374011848795,0.7020226932379363,0.730826559921213,0.615366695909301,0.087264561932277,0.14667069399718627,4.612142867783727,0.7020226932379363,-0.03212892744333096,0.5573891868193322
2,448
Signaling by interleukins
44
99
2.385014
0.017078
Q92530,P48556,P04179,P04083,Q13200,P08670,P11233,P25789,Q06124,P51452,P09429,P14174,Q99439,P62993,P25787,P49721,O14979,Q99460,P28072,P28074,Q9UL46,P28070,Q00169,Q9UNM6,O00231,Q99436,P17612,P63208,P26038,P35998,P51665,P63104,P60953,P20618,Q13126,O43242,Q13177,P40763,P60900,Q15008,Q15418,P22626,Q06323,P30153
Processes and pathways
Reactome Pathways
msigdb_reactome
397,260,142,15,390,515,517,275,295,525,653,35,39,293,291,167,287,581,49,51,588,54,315,724,550,69,686,439,689,691,77,698,595,220,222,227,626,241,484,488,489,615,531,618
1041,550,946,1766,730,287,227,1872,15,142,2203,2430,1576,1769,1532,1771,1002,515,653,2144,1173,1050,517,35,1690,686,1052,825,220,1004,615,1267,1310,291,1268,275,689,1221,1361,1727,54,49,51,1494,618,961,691,1366,2207,830,241,1270,1650,1776,260,1728,167,525,1807,77,2148,1227,1228,916,1102,484,595,782,969,697,1503,1463,293,698,439,920,315,786,295,531,222,626,390,2025,1109,843,488,489,1469,2311,1027,884,397,69,39,581,937,588,724
0.087264561932277,0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.7595902108481608,0.9028157215260153,-0.5179988657470733,4.161025061636598,1.2145752253051996,-0.8605609719945663,-3.0085610162180214,-0.27334151033073334,-0.42583141250889395,-0.24300698162028928,-0.42583141250889395,0.11699149062391306,0.47010609080532134,0.3531228099863507,-0.7977141188950565,-0.002206819462379813,0.087264561932277,0.47010609080532134,2.3409658129140403,-0.364669859579678,0.3237664369124269,0.087264561932277,0.23542606283924014,0.9313443171057458,0.11699149062391306,0.38243459835151017,-0.06210093493456228,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,0.3237664369124269,-0.03212892744333096,-0.12219648225605645,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.21272571549189503,0.38243459835151017,0.14667069399718627,0.3237664369124269,-0.12219648225605645,-0.8605609719945663,0.23542606283924014,0.8742486728862037,-0.06210093493456228,-0.33417242136584113,-0.42583141250889395,0.8169980768047461,-0.3952226726312979,1.1017238127490079,0.47010609080532134,-0.4564966412770062,1.6880249517622525,-0.7977141188950565,-0.03212892744333096,-0.03212892744333096,0.17630258634391707,0.05748948699344504,0.4992431492624739,0.4117021682718201,0.2649184437199032,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.7595902108481608,0.3237664369124269,0.5573891868193322,0.17630258634391707,0.730826559921213,0.2649184437199032,0.7595902108481608,0.47010609080532134,0.9313443171057458,0.38243459835151017,0.615366695909301,-0.6417070956037559,0.05748948699344504,0.23542606283924014,0.4992431492624739,0.4992431492624739,-0.182497206611748,-1.0507002473854663,0.11699149062391306,0.2058875754695338,0.615366695909301,1.7705913566526543,2.1251973259084997,0.4409258805823772,0.17630258634391707,0.4409258805823772,0.3237664369124269
2,448
Nucleophile aminohydrolases, N-terminal [IPR029055]
8
19
2.379799
0.017322
Q99436,Q9UJ14,P49721,P28072,P28074,P28070,P25789,P20618
Sequence
InterPro Superfamily
interpro_homologous_superfamily
69,271,167,49,51,54,275,220
730,612,220,1310,291,1268,275,1727,54,49,51,1728,167,484,1464,2186,2078,69,271
0.29436510731780724,0.38243459835151017,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.3952226726312979,1.1017238127490079,0.4992431492624739,-0.182497206611748,-0.8291051207987041,-0.7039230664205183,1.7705913566526543,0.8169980768047461
2,448