term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
SH3-like domain superfamily [IPR036028]
6
15
2.376681
0.017469
Q9UQB8,P62993,Q14847,Q9UDY2,Q9NZW5,Q5JRA6
Sequence
InterPro Superfamily
interpro_homologous_superfamily
134,293,138,46,246,28
831,1776,293,1235,842,574,138,28,720,246,46,1124,134,362,1346
0.23542606283924014,-0.42583141250889395,0.7595902108481608,-0.03212892744333096,0.23542606283924014,0.4409258805823772,1.2426985519939489,2.5283117833572146,0.3237664369124269,0.8742486728862037,1.9621626060274844,0.05748948699344504,1.2707865591544374,0.6731783026903564,-0.09212329847709767
2,448
Negative regulation of cell differentiation
23
65
2.372377
0.017674
Q96T37,Q8N4Q0,P04179,P04083,Q99873,P61586,Q06124,O60271,Q8WX92,Q6PD62,Q9UPY3,Q13247,Q92688,Q9NYV4,Q9P258,Q96G23,P11413,Q9Y5A9,Q8N0X7,P40763,Q00535,O14744,O15347
Processes and pathways
GO Biological process
msigdb_gobp
267,12,142,15,283,25,295,408,50,58,60,73,213,359,360,93,342,236,373,241,370,237,248
237,508,248,1259,408,1351,1874,15,142,2203,2430,1769,734,552,653,342,412,1099,1493,1137,1494,657,1139,913,1407,2207,241,1270,1318,1925,25,2332,528,370,2152,572,295,2354,2333,73,747,789,2157,793,750,58,373,12,1551,50,213,577,2081,93,267,2318,283,1339,2356,2031,359,360,1297,60,236
0.8742486728862037,0.47010609080532134,0.8456428872388043,-0.06210093493456228,0.5863988415320117,-0.12219648225605645,-0.5179988657470733,4.161025061636598,1.2145752253051996,-0.8605609719945663,-3.0085610162180214,-0.42583141250889395,0.29436510731780724,0.4409258805823772,0.3531228099863507,0.6731783026903564,0.5863988415320117,0.05748948699344504,-0.21272571549189503,0.027665838086341914,-0.21272571549189503,0.3531228099863507,0.027665838086341914,0.17630258634391707,-0.15232095828757117,-0.8605609719945663,0.8742486728862037,-0.06210093493456228,-0.09212329847709767,-0.5488370384270144,2.581598099731636,-1.1467083845303592,0.47010609080532134,0.6442930758559092,-0.7977141188950565,0.4409258805823772,0.7595902108481608,-1.243358299991923,-1.1467083845303592,1.7431006951795138,0.29436510731780724,0.2649184437199032,-0.7977141188950565,0.2649184437199032,0.29436510731780724,1.825479230161245,0.6442930758559092,4.437434635650035,-0.24300698162028928,1.9075802654498024,0.9598347398148359,0.4409258805823772,-0.7039230664205183,1.4942473318432876,0.8169980768047461,-1.0826315524646415,0.7883139498979853,-0.09212329847709767,-1.243358299991923,-0.6417070956037559,0.6731783026903564,0.6731783026903564,-0.06210093493456228,1.825479230161245,0.9028157215260153
2,448
Cell cycle checkpoints
49
115
2.372207
0.017682
Q92530,Q16763,Q9UQ84,P51530,P48556,Q9NXR7,Q9Y6G9,Q9UJX4,Q13200,Q92547,O43683,O43264,P25789,P27694,P30260,Q04917,P33991,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,O43237,P14635,Q99436,P06493,P35998,P51665,Q9Y266,P33993,P63104,P62191,Q9P258,Q7Z460,P20618,Q15008,Q13409,O43242,Q15691,Q8NFH4,Q9UJX2,P60900,P15927,Q06323,P30153
Processes and pathways
Reactome Pathways
msigdb_reactome
397,264,10,261,260,146,286,285,390,157,645,644,275,655,519,572,658,291,167,581,49,51,588,54,724,550,551,555,69,683,691,77,480,592,698,697,360,752,220,488,231,227,112,114,115,484,251,531,618
1483,550,946,1766,730,1401,551,227,644,645,768,1913,1571,2357,1872,1684,1685,2203,683,555,251,1003,1052,220,738,1310,291,1268,275,1311,655,1727,54,49,51,618,961,519,1455,658,1497,592,1960,1498,691,1011,963,1650,1694,260,1728,167,1060,1729,1653,261,77,1655,1585,2069,1102,1231,484,782,969,783,697,1503,1586,1463,2332,698,2361,572,531,1506,1811,390,231,1149,881,1074,1850,843,1886,488,112,264,1110,2127,752,114,754,1634,397,157,1333,1938,69,581,1713,1900,1940,1161,1437,146,360,115,1207,285,588,724,10,480,286
-0.21272571549189503,0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,-0.15232095828757117,0.4409258805823772,0.9028157215260153,0.3531228099863507,0.3531228099863507,0.2649184437199032,-0.5488370384270144,-0.27334151033073334,-1.2757154640498929,-0.5179988657470733,-0.364669859579678,-0.364669859579678,-0.8605609719945663,0.3237664369124269,0.4409258805823772,0.8456428872388043,0.11699149062391306,0.087264561932277,0.9313443171057458,0.29436510731780724,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.09212329847709767,0.3531228099863507,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.38243459835151017,0.14667069399718627,0.47010609080532134,-0.182497206611748,0.3531228099863507,-0.21272571549189503,0.4117021682718201,-0.5797340545401417,-0.21272571549189503,0.3237664369124269,0.11699149062391306,0.14667069399718627,-0.33417242136584113,-0.364669859579678,0.8169980768047461,-0.3952226726312979,1.1017238127490079,0.087264561932277,-0.3952226726312979,-0.33417242136584113,0.8169980768047461,1.6880249517622525,-0.33417242136584113,-0.27334151033073334,-0.7039230664205183,0.05748948699344504,-0.03212892744333096,0.4992431492624739,0.2649184437199032,0.14667069399718627,0.2649184437199032,0.3237664369124269,-0.21272571549189503,-0.27334151033073334,-0.182497206611748,-1.1467083845303592,0.3237664369124269,-1.2757154640498929,0.4409258805823772,0.47010609080532134,-0.21272571549189503,-0.4564966412770062,0.615366695909301,0.9028157215260153,0.027665838086341914,0.2058875754695338,0.087264561932277,-0.4872189313453426,0.23542606283924014,-0.5179988657470733,0.4992431492624739,1.3548410508645194,0.8169980768047461,0.05748948699344504,-0.7663872448501347,0.29436510731780724,1.3548410508645194,0.29436510731780724,-0.30372981581819986,0.615366695909301,1.1582216374253231,-0.09212329847709767,-0.5488370384270144,1.7705913566526543,0.4409258805823772,-0.364669859579678,-0.5179988657470733,-0.5488370384270144,0.027665838086341914,-0.15232095828757117,1.2145752253051996,0.6731783026903564,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.3237664369124269,4.66189423786694,0.5283374011848795,0.7883139498979853
2,448
Wound healing
8
44
2.368274
0.017871
O43633,P04792,Q99439,Q13247,P04083,P61586,Q96AY3,Q5JRA6
Processes and pathways
GO Biological process
msigdb_gobp
130,6,39,73,15,25,26,28
2035,1168,1042,130,15,6,1769,1578,2144,684,1624,614,1005,1139,523,180,1408,2414,1226,564,437,780,25,1019,73,1781,371,2072,2212,665,2311,28,752,2397,351,2081,26,2052,39,1752,1521,2264,361,405
-0.6727843897556249,-0.002206819462379813,0.087264561932277,1.2707865591544374,4.161025061636598,5.931560240339164,-0.42583141250889395,-0.27334151033073334,-0.7977141188950565,0.3237664369124269,-0.30372981581819986,0.38243459835151017,0.11699149062391306,0.027665838086341914,0.47010609080532134,1.0450797177342925,-0.15232095828757117,-2.105990413747261,-0.03212892744333096,0.4409258805823772,0.5573891868193322,0.2649184437199032,2.581598099731636,0.11699149062391306,1.7431006951795138,-0.42583141250889395,0.6442930758559092,-0.7039230664205183,-0.8605609719945663,0.3531228099863507,-1.0507002473854663,2.5283117833572146,0.29436510731780724,-1.603022665769443,0.6731783026903564,-0.7039230664205183,2.5549681424265085,-0.6727843897556249,2.1251973259084997,-0.3952226726312979,-0.21272571549189503,-0.9236701828387313,0.6731783026903564,0.615366695909301
2,448
Positive regulation of ion transport
15
30
2.360099
0.01827
P28161,P14174,P11413,P55011,P27695,P30626,P17931,Q07812,Q15042,Q00535,P50570,P54652,P0DP25,O14745,P35609
Processes and pathways
GO Biological process
msigdb_gobp
116,35,342,437,344,413,368,485,209,370,469,311,240,207,434
1677,207,1259,1687,1769,1990,240,342,35,368,1625,1309,1005,344,116,413,522,434,469,2148,311,1141,437,920,370,485,1377,209,1122,863
-0.364669859579678,0.9598347398148359,-0.06210093493456228,-0.364669859579678,-0.42583141250889395,-0.6106905307608944,0.8742486728862037,0.6731783026903564,2.3409658129140403,0.6442930758559092,-0.30372981581819986,-0.09212329847709767,0.11699149062391306,0.6731783026903564,1.3268575727799916,0.5863988415320117,0.47010609080532134,0.5573891868193322,0.5283374011848795,-0.7977141188950565,0.730826559921213,0.027665838086341914,0.5573891868193322,0.17630258634391707,0.6442930758559092,0.4992431492624739,-0.12219648225605645,0.9598347398148359,0.05748948699344504,0.23542606283924014
2,448
Transferase activity transferring one carbon groups
21
52
2.340597
0.019253
O75648,Q08J23,Q99873,Q7L2J0,Q9H7B4,Q6FI81,Q8IZ69,P34896,Q99707,Q86X55,P57081,Q8NCA5,Q14353,Q9BV44,O15047,P61964,Q9H9B1,Q05682,O60678,O14744,Q8N6R0
Functions
GO Molecular function
msigdb_gomf
381,389,283,151,24,420,40,42,168,445,174,447,57,188,61,67,335,440,218,237,396
237,61,949,812,218,1616,381,1685,2142,1053,2018,826,1099,911,1648,42,1363,2182,174,67,2024,440,389,927,57,2157,1077,1547,848,2191,420,1745,1283,151,445,1709,40,1594,396,447,1556,1712,2337,168,283,188,2282,24,501,335,2283,1397
0.8742486728862037,1.798050804303417,0.14667069399718627,0.23542606283924014,0.9313443171057458,-0.30372981581819986,0.615366695909301,-0.364669859579678,-0.7977141188950565,0.087264561932277,-0.6417070956037559,0.23542606283924014,0.05748948699344504,0.17630258634391707,-0.33417242136584113,2.016625291546481,-0.12219648225605645,-0.8291051207987041,1.0734201781652684,1.7705913566526543,-0.6417070956037559,0.5573891868193322,0.615366695909301,0.17630258634391707,1.825479230161245,-0.7977141188950565,0.087264561932277,-0.24300698162028928,0.23542606283924014,-0.8291051207987041,0.5863988415320117,-0.3952226726312979,-0.06210093493456228,1.1864163358736073,0.5573891868193322,-0.364669859579678,2.0438122069225027,-0.27334151033073334,0.615366695909301,0.5573891868193322,-0.24300698162028928,-0.364669859579678,-1.1467083845303592,1.1017238127490079,0.7883139498979853,1.0450797177342925,-0.9553250615605502,2.7408312506583243,0.4992431492624739,0.7020226932379363,-0.9553250615605502,-0.12219648225605645
2,448
Vasculature development
13
73
2.333704
0.019611
O75340,Q9H2J4,P04792,Q96T37,Q9BXJ9,P04179,P04083,Q92688,P35613,P40763,P61586,Q96AY3,Q5JRA6
Processes and pathways
GO Biological process
msigdb_gobp
160,101,6,267,255,142,15,213,76,241,25,26,28
508,1351,160,1835,512,1304,15,142,6,1769,2306,1771,2144,1579,1580,1453,1266,1005,274,1099,1494,1407,523,76,1011,241,1270,2414,1226,1776,695,1925,1101,437,595,25,1278,698,878,597,786,440,2354,1235,485,1069,923,1781,1507,627,2212,2074,793,1887,1469,2311,1191,28,2159,2050,213,933,1858,26,1157,542,267,255,101,1756,862,425,728
0.47010609080532134,-0.12219648225605645,1.1299908805711318,-0.4872189313453426,0.47010609080532134,-0.09212329847709767,4.161025061636598,1.2145752253051996,5.931560240339164,-0.42583141250889395,-1.0507002473854663,-0.42583141250889395,-0.7977141188950565,-0.27334151033073334,-0.27334151033073334,-0.182497206611748,-0.06210093493456228,0.11699149062391306,0.7883139498979853,0.05748948699344504,-0.21272571549189503,-0.15232095828757117,0.47010609080532134,1.6880249517622525,0.11699149062391306,0.8742486728862037,-0.06210093493456228,-2.105990413747261,-0.03212892744333096,-0.42583141250889395,0.3237664369124269,-0.5488370384270144,0.05748948699344504,0.5573891868193322,0.4117021682718201,2.581598099731636,-0.06210093493456228,0.3237664369124269,0.2058875754695338,0.4117021682718201,0.2649184437199032,0.5573891868193322,-1.243358299991923,-0.03212892744333096,0.4992431492624739,0.087264561932277,0.17630258634391707,-0.42583141250889395,-0.21272571549189503,0.38243459835151017,-0.8605609719945663,-0.7039230664205183,0.2649184437199032,-0.5179988657470733,-0.182497206611748,-1.0507002473854663,-0.002206819462379813,2.5283117833572146,-0.7977141188950565,-0.6727843897556249,0.9598347398148359,0.17630258634391707,-0.4872189313453426,2.5549681424265085,0.027665838086341914,0.47010609080532134,0.8169980768047461,0.8456428872388043,1.4385861401124023,-0.3952226726312979,0.23542606283924014,0.5863988415320117,0.3237664369124269
2,448
The role of gtse1 in g2 m progression after g2 checkpoint
21
47
2.325297
0.020056
P48556,Q13200,P25789,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,O00231,Q99436,P51665,Q9BUF5,P20618,O43242,Q15691,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,291,167,581,49,51,588,54,550,69,77,354,220,227,112,484,488,531,397
550,946,1766,730,227,1872,2203,683,1002,1172,555,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,77,1585,1102,484,969,697,1503,1463,699,531,390,2211,488,112,397,69,581,354,2351,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.8605609719945663,0.3237664369124269,0.11699149062391306,-0.002206819462379813,0.4409258805823772,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,-0.27334151033073334,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.3237664369124269,0.47010609080532134,0.615366695909301,-0.8605609719945663,0.4992431492624739,1.3548410508645194,0.615366695909301,1.7705913566526543,0.4409258805823772,0.6731783026903564,-1.211071046856623,0.4409258805823772,0.3237664369124269
2,448
calmodulin-related
7
11
2.311609
0.020799
Q14257,P30626,P31949,P80303,P0DP25,Q02818,Q99584
Functions
Panther Protein class
panther_protein_class
441,413,414,107,240,182,127
1302,240,413,414,1369,107,182,441,1381,127,583
-0.09212329847709767,0.8742486728862037,0.5863988415320117,0.5863988415320117,-0.12219648225605645,1.3827901527630164,1.0450797177342925,0.5573891868193322,-0.12219648225605645,1.298839486996753,0.4409258805823772
2,448
Transcriptional regulation by runx3
18
42
2.309901
0.020894
Q99436,Q15008,P25787,P49721,P48556,O43242,Q99460,P51665,P28072,P28074,P60900,Q13200,Q9UL46,P28070,P20618,P25789,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
69,488,291,167,260,227,581,77,49,51,484,390,588,54,220,275,531,397
550,946,1766,730,227,1872,2203,1052,220,959,1310,291,1268,275,1727,54,49,51,1407,691,1650,260,1728,167,77,1102,484,969,697,1503,1463,531,2354,390,1378,789,488,397,69,581,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-0.8605609719945663,0.087264561932277,0.9313443171057458,0.14667069399718627,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.15232095828757117,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.47010609080532134,-1.243358299991923,0.615366695909301,-0.12219648225605645,0.2649184437199032,0.4992431492624739,0.615366695909301,1.7705913566526543,0.4409258805823772,0.4409258805823772,0.3237664369124269
2,448
Blood vessel morphogenesis
11
60
2.267541
0.023357
O75340,Q9H2J4,P04792,Q96T37,Q9BXJ9,P04083,P35613,P40763,P61586,Q96AY3,Q5JRA6
Processes and pathways
GO Biological process
msigdb_gobp
160,101,6,267,255,15,76,241,25,26,28
508,160,1835,512,1304,15,6,1769,2306,1771,2144,1579,1580,1453,1266,1005,274,1407,523,76,1011,241,1270,2414,1226,695,1925,1101,437,595,25,698,878,597,440,2354,1235,485,1069,923,1507,627,2212,793,2311,1191,28,2159,2050,933,1858,26,1157,542,267,255,101,1756,862,728
0.47010609080532134,1.1299908805711318,-0.4872189313453426,0.47010609080532134,-0.09212329847709767,4.161025061636598,5.931560240339164,-0.42583141250889395,-1.0507002473854663,-0.42583141250889395,-0.7977141188950565,-0.27334151033073334,-0.27334151033073334,-0.182497206611748,-0.06210093493456228,0.11699149062391306,0.7883139498979853,-0.15232095828757117,0.47010609080532134,1.6880249517622525,0.11699149062391306,0.8742486728862037,-0.06210093493456228,-2.105990413747261,-0.03212892744333096,0.3237664369124269,-0.5488370384270144,0.05748948699344504,0.5573891868193322,0.4117021682718201,2.581598099731636,0.3237664369124269,0.2058875754695338,0.4117021682718201,0.5573891868193322,-1.243358299991923,-0.03212892744333096,0.4992431492624739,0.087264561932277,0.17630258634391707,-0.21272571549189503,0.38243459835151017,-0.8605609719945663,0.2649184437199032,-1.0507002473854663,-0.002206819462379813,2.5283117833572146,-0.7977141188950565,-0.6727843897556249,0.17630258634391707,-0.4872189313453426,2.5549681424265085,0.027665838086341914,0.47010609080532134,0.8169980768047461,0.8456428872388043,1.4385861401124023,-0.3952226726312979,0.23542606283924014,0.3237664369124269
2,448
Enzyme linked receptor protein signaling pathway
26
90
2.261894
0.023704
P04792,Q9UQB8,P16949,P43490,Q9UQ13,Q06124,O75340,P62993,Q9Y5X3,O00400,Q13526,Q9H1E3,Q9Y2U8,P53999,Q99816,O14745,Q9UIQ6,Q6Y7W6,Q93034,Q96B36,P27695,Q15942,P49354,P40763,Q8N0X7,P11802
Processes and pathways
GO Biological process
msigdb_gobp
6,134,384,17,426,295,160,293,321,48,175,66,337,72,332,207,87,89,352,100,344,108,242,241,373,366
1611,48,994,207,508,1129,1349,770,160,512,2203,6,1769,1172,515,1049,1452,366,1838,384,1219,2040,1221,344,1494,1626,1407,241,17,1776,964,242,1318,469,1995,525,72,1502,293,1698,879,295,2354,2333,923,626,175,1378,2187,1592,1469,108,2311,1855,89,599,1028,373,885,1115,853,422,2193,2418,2235,855,352,2081,100,2052,798,2318,2217,332,1792,1160,66,938,2031,2168,87,1720,1299,546,426,134,337,726,1209,321
-0.30372981581819986,1.9075802654498024,0.11699149062391306,0.9598347398148359,0.47010609080532134,0.027665838086341914,-0.12219648225605645,0.2649184437199032,1.1299908805711318,0.47010609080532134,-0.8605609719945663,5.931560240339164,-0.42583141250889395,-0.002206819462379813,0.47010609080532134,0.087264561932277,-0.182497206611748,0.6442930758559092,-0.4872189313453426,0.615366695909301,-0.03212892744333096,-0.6727843897556249,-0.03212892744333096,0.6731783026903564,-0.21272571549189503,-0.30372981581819986,-0.15232095828757117,0.8742486728862037,3.856772038666039,-0.42583141250889395,0.14667069399718627,0.8742486728862037,-0.09212329847709767,0.5283374011848795,-0.6106905307608944,0.47010609080532134,1.7431006951795138,-0.21272571549189503,0.7595902108481608,-0.364669859579678,0.2058875754695338,0.7595902108481608,-1.243358299991923,-1.1467083845303592,0.17630258634391707,0.38243459835151017,1.0734201781652684,-0.12219648225605645,-0.8291051207987041,-0.27334151033073334,-0.182497206611748,1.3827901527630164,-1.0507002473854663,-0.4872189313453426,1.522027929261891,0.4117021682718201,0.11699149062391306,0.6442930758559092,0.2058875754695338,0.05748948699344504,0.23542606283924014,0.5863988415320117,-0.8291051207987041,-2.3797319420179317,-0.8920824087947153,0.23542606283924014,0.6731783026903564,-0.7039230664205183,1.4385861401124023,-0.6727843897556249,0.2649184437199032,-1.0826315524646415,-0.8605609719945663,0.7020226932379363,-0.42583141250889395,0.027665838086341914,1.798050804303417,0.17630258634391707,-0.6417070956037559,-0.7977141188950565,1.5497754824846934,-0.364669859579678,-0.06210093493456228,0.47010609080532134,0.5863988415320117,1.2707865591544374,0.7020226932379363,0.3237664369124269,-0.002206819462379813,0.730826559921213
2,448
Transmembrane receptor protein tyrosine kinase signaling pathway
18
56
2.255562
0.024098
O75340,Q96B36,Q9H1E3,P11802,Q9UQB8,P04792,P62993,Q99816,P27695,P16949,Q9Y5X3,P43490,P40763,O14745,Q9UQ13,Q6Y7W6,Q93034,Q06124
Processes and pathways
GO Biological process
msigdb_gobp
160,100,66,366,134,6,293,332,344,384,321,17,241,207,426,89,352,295
1611,994,207,508,1129,1349,770,160,512,6,1452,366,1838,384,2040,344,1494,1407,241,17,1776,964,1318,1995,525,1502,293,295,2354,923,626,2311,1855,89,599,1028,1115,853,422,2235,352,100,2052,2318,2217,332,1792,66,938,2031,2168,1720,1299,426,134,321
-0.30372981581819986,0.11699149062391306,0.9598347398148359,0.47010609080532134,0.027665838086341914,-0.12219648225605645,0.2649184437199032,1.1299908805711318,0.47010609080532134,5.931560240339164,-0.182497206611748,0.6442930758559092,-0.4872189313453426,0.615366695909301,-0.6727843897556249,0.6731783026903564,-0.21272571549189503,-0.15232095828757117,0.8742486728862037,3.856772038666039,-0.42583141250889395,0.14667069399718627,-0.09212329847709767,-0.6106905307608944,0.47010609080532134,-0.21272571549189503,0.7595902108481608,0.7595902108481608,-1.243358299991923,0.17630258634391707,0.38243459835151017,-1.0507002473854663,-0.4872189313453426,1.522027929261891,0.4117021682718201,0.11699149062391306,0.05748948699344504,0.23542606283924014,0.5863988415320117,-0.8920824087947153,0.6731783026903564,1.4385861401124023,-0.6727843897556249,-1.0826315524646415,-0.8605609719945663,0.7020226932379363,-0.42583141250889395,1.798050804303417,0.17630258634391707,-0.6417070956037559,-0.7977141188950565,-0.364669859579678,-0.06210093493456228,0.5863988415320117,1.2707865591544374,0.730826559921213
2,448
Cytoplasmic stress granule
24
42
2.254754
0.024149
Q92499,Q8WWM7,O60828,P67809,Q14011,O95793,Q04637,O75534,P26196,Q6PKG0,Q9UN86,Q7Z417,Q14258,Q14974,P06730,Q8N543,P61978,P05198,Q6Y7W6,Q9Y5A9,Q9Y520,Q13148,Q13310,Q14157
Localization
GO Cellular component
msigdb_gocc
672,539,259,528,150,652,278,647,412,576,723,444,442,705,552,330,438,463,89,236,506,346,371,122
1399,259,647,652,463,552,1051,412,1368,438,528,1588,278,1544,346,924,371,1507,150,122,442,790,1021,705,2003,576,89,1113,444,330,539,672,756,2336,1337,892,1203,1638,1675,723,506,236
-0.15232095828757117,0.8169980768047461,0.3531228099863507,0.3531228099863507,0.5283374011848795,0.4409258805823772,0.087264561932277,0.5863988415320117,-0.12219648225605645,0.5573891868193322,0.47010609080532134,-0.27334151033073334,0.7883139498979853,-0.24300698162028928,0.6731783026903564,0.17630258634391707,0.6442930758559092,-0.21272571549189503,1.1864163358736073,1.298839486996753,0.5573891868193322,0.2649184437199032,0.11699149062391306,0.3237664369124269,-0.6106905307608944,0.4409258805823772,1.522027929261891,0.05748948699344504,0.5573891868193322,0.7020226932379363,0.47010609080532134,0.3531228099863507,0.29436510731780724,-1.1467083845303592,-0.09212329847709767,0.2058875754695338,-0.002206819462379813,-0.30372981581819986,-0.33417242136584113,0.3237664369124269,0.4992431492624739,0.9028157215260153
2,448
Cilium organization
14
36
2.252837
0.024269
Q9NT62,P18085,A6NIH7,Q15555,P27695,Q9H4M9,Q14203,Q9BW83,O00471,Q15691,Q9H223,Q9UBB4,O14745,Q8TC07
Processes and pathways
GO Biological process
msigdb_gobp
128,433,36,296,344,333,262,45,110,112,214,479,207,186
36,110,207,1001,736,433,1005,344,912,1583,1318,1100,469,1963,1880,1183,1882,2361,262,1422,296,112,977,979,670,186,1115,797,45,214,333,128,479,763,2265,1609
2.314092963919821,1.3548410508645194,0.9598347398148359,0.11699149062391306,0.29436510731780724,0.5573891868193322,0.11699149062391306,0.6731783026903564,0.17630258634391707,-0.27334151033073334,-0.09212329847709767,0.05748948699344504,0.5283374011848795,-0.5797340545401417,-0.5179988657470733,-0.002206819462379813,-0.5179988657470733,-1.2757154640498929,0.8169980768047461,-0.15232095828757117,0.7595902108481608,1.3548410508645194,0.14667069399718627,0.14667069399718627,0.3531228099863507,1.0450797177342925,0.05748948699344504,0.2649184437199032,1.9621626060274844,0.9598347398148359,0.7020226932379363,1.298839486996753,0.5283374011848795,0.29436510731780724,-0.9236701828387313,-0.27334151033073334
2,448
Signaling receptor binding
42
143
2.251836
0.024333
P02656,Q9Y624,O60749,P04083,P43490,Q9NXR7,Q9BUN8,Q9BQE5,Q92600,Q06124,Q8TEY7,P14174,O43768,P62993,P30626,P56537,Q9Y5X3,Q15257,Q14258,P35609,P55145,P41440,P51858,O14745,Q9Y490,Q9Y5K6,Q9NUQ9,Q9H2J4,O43776,P17096,P27695,Q9UMX5,P11047,P49354,P40763,P0DP25,P17931,Q00535,P28161,O75312,Q96J02,Q99584
Functions
GO Molecular function
msigdb_gomf
2,405,258,15,17,146,159,158,422,295,300,35,407,293,413,313,321,55,442,434,191,71,199,207,361,362,235,101,339,97,344,106,229,242,241,240,368,370,116,363,126,127
1611,1041,994,207,995,1259,407,339,867,1403,258,770,363,1681,1835,1836,1170,2,2369,15,1575,2203,2430,1769,2423,2306,910,1532,1132,818,1172,1451,653,1097,240,229,1050,517,1689,684,35,1690,555,97,368,2040,433,1647,1005,1959,2324,689,344,1137,1361,116,617,1921,413,558,2205,523,434,241,71,1270,17,1776,562,876,2041,242,469,525,2286,199,741,696,1368,191,313,1809,595,783,1503,293,1066,1698,699,370,1067,1019,572,295,1146,1069,1966,925,2025,1378,663,1702,974,442,2212,2074,55,1078,793,2046,2276,300,716,1115,2163,422,2418,933,2081,1514,1973,126,719,2303,127,158,159,1753,937,101,235,146,1440,106,1720,1299,547,726,361,1209,362,321,405
-0.30372981581819986,0.087264561932277,0.11699149062391306,0.9598347398148359,0.11699149062391306,-0.06210093493456228,0.5863988415320117,0.6731783026903564,0.2058875754695338,-0.15232095828757117,0.8169980768047461,0.2649184437199032,0.6442930758559092,-0.364669859579678,-0.4872189313453426,-0.4872189313453426,-0.002206819462379813,6.997268324204374,-1.3406374671292853,4.161025061636598,-0.27334151033073334,-0.8605609719945663,-3.0085610162180214,-0.42583141250889395,-2.587405849616877,-1.0507002473854663,0.17630258634391707,-0.24300698162028928,0.027665838086341914,0.23542606283924014,-0.002206819462379813,-0.182497206611748,0.3531228099863507,0.05748948699344504,0.8742486728862037,0.9028157215260153,0.087264561932277,0.47010609080532134,-0.364669859579678,0.3237664369124269,2.3409658129140403,-0.364669859579678,0.4409258805823772,1.4385861401124023,0.6442930758559092,-0.6727843897556249,0.5573891868193322,-0.33417242136584113,0.11699149062391306,-0.5797340545401417,-1.114634054017247,0.3237664369124269,0.6731783026903564,0.027665838086341914,-0.12219648225605645,1.3268575727799916,0.38243459835151017,-0.5488370384270144,0.5863988415320117,0.4409258805823772,-0.8605609719945663,0.47010609080532134,0.5573891868193322,0.8742486728862037,1.7431006951795138,-0.06210093493456228,3.856772038666039,-0.42583141250889395,0.4409258805823772,0.2058875754695338,-0.6727843897556249,0.8742486728862037,0.5283374011848795,0.47010609080532134,-0.987047828674115,0.9882872661563274,0.29436510731780724,0.3237664369124269,-0.12219648225605645,1.0167021690167521,0.730826559921213,-0.4564966412770062,0.4117021682718201,0.2649184437199032,-0.21272571549189503,0.7595902108481608,0.087264561932277,-0.364669859579678,0.3237664369124269,0.6442930758559092,0.087264561932277,0.11699149062391306,0.4409258805823772,0.7595902108481608,0.027665838086341914,0.087264561932277,-0.5797340545401417,0.17630258634391707,-0.6417070956037559,-0.12219648225605645,0.3531228099863507,-0.364669859579678,0.14667069399718627,0.5573891868193322,-0.8605609719945663,-0.7039230664205183,1.8528768241204838,0.087264561932277,0.2649184437199032,-0.6727843897556249,-0.9553250615605502,0.7595902108481608,0.3237664369124269,0.05748948699344504,-0.7977141188950565,0.5863988415320117,-2.3797319420179317,0.17630258634391707,-0.7039230664205183,-0.21272571549189503,-0.5797340545401417,1.298839486996753,0.3237664369124269,-1.0188392846787804,1.298839486996753,1.1582216374253231,1.1582216374253231,-0.3952226726312979,0.17630258634391707,1.4385861401124023,0.9028157215260153,1.2145752253051996,-0.15232095828757117,1.4107051071903693,-0.364669859579678,-0.06210093493456228,0.47010609080532134,0.3237664369124269,0.6731783026903564,-0.002206819462379813,0.6731783026903564,0.730826559921213,0.615366695909301
2,448
Protein polyubiquitination
16
38
2.222366
0.026259
P30260,Q7Z6Z7,P63208,Q16763,Q13867,Q15386,Q9Y4X5,P19474,Q9UJX4,Q9UJX2,Q9UIQ6,Q5VTR2,Q9ULT8,P55786,Q96J02,Q14139
Processes and pathways
GO Biological process
msigdb_gobp
519,634,439,264,347,392,178,18,285,115,87,443,425,118,126,533
1399,950,869,2038,18,1454,519,1407,1011,915,118,968,782,439,661,1109,1702,347,789,533,1815,392,264,443,634,638,126,1160,1940,87,115,1207,285,425,2089,1720,178,943
-0.15232095828757117,0.14667069399718627,0.2058875754695338,-0.6727843897556249,3.7035378773687953,-0.182497206611748,0.47010609080532134,-0.15232095828757117,0.11699149062391306,0.17630258634391707,1.3268575727799916,0.14667069399718627,0.2649184437199032,0.5573891868193322,0.3531228099863507,0.05748948699344504,-0.364669859579678,0.6731783026903564,0.2649184437199032,0.47010609080532134,-0.4564966412770062,0.615366695909301,0.8169980768047461,0.5573891868193322,0.38243459835151017,0.38243459835151017,1.298839486996753,0.027665838086341914,-0.5488370384270144,1.5497754824846934,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.5863988415320117,-0.7039230664205183,-0.364669859579678,1.0734201781652684,0.17630258634391707
2,448
Protein monoubiquitination
9
18
2.222297
0.026263
O75340,Q99816,P63208,Q96T88,Q9UBV8,P19474,Q5VTR2,Q6PD62,Q14258
Processes and pathways
GO Biological process
msigdb_gobp
160,332,439,499,604,18,443,58,442
950,160,18,439,1109,1702,1591,442,1324,443,750,58,634,1551,499,332,1160,604
0.14667069399718627,1.1299908805711318,3.7035378773687953,0.5573891868193322,0.05748948699344504,-0.364669859579678,-0.27334151033073334,0.5573891868193322,-0.09212329847709767,0.5573891868193322,0.29436510731780724,1.825479230161245,0.38243459835151017,-0.24300698162028928,0.4992431492624739,0.7020226932379363,0.027665838086341914,0.4117021682718201
2,448
I band
8
24
2.213309
0.026876
Q8WX93,P04792,Q9Y281,Q9Y376,P30626,O00151,Q16637,P35609
Localization
GO Cellular component
msigdb_gocc
162,6,204,170,413,428,156,434
428,1259,952,1618,1724,6,684,1580,1005,413,1407,434,1019,1377,1073,471,665,156,162,2081,580,1720,204,170
0.5573891868193322,-0.06210093493456228,0.14667069399718627,-0.30372981581819986,-0.3952226726312979,5.931560240339164,0.3237664369124269,-0.27334151033073334,0.11699149062391306,0.5863988415320117,-0.15232095828757117,0.5573891868193322,0.11699149062391306,-0.12219648225605645,0.087264561932277,0.5283374011848795,0.3531228099863507,1.1582216374253231,1.1299908805711318,-0.7039230664205183,0.4409258805823772,-0.364669859579678,0.9882872661563274,1.1017238127490079
2,448
Chaperone mediated protein folding
9
35
2.210773
0.027052
Q9H2J4,P04792,Q13451,O00273,O14737,P25685,P54652,O75718,Q02790
Processes and pathways
GO Biological process
msigdb_gobp
101,6,232,226,322,208,311,306,193
226,322,1678,306,6,1097,1050,1918,825,2019,208,468,2207,1537,1651,1059,1181,1539,311,2184,785,193,1465,922,1966,232,748,795,755,934,1200,1335,101,355,1122
0.9028157215260153,0.7020226932379363,-0.364669859579678,0.730826559921213,5.931560240339164,0.05748948699344504,0.087264561932277,-0.5488370384270144,0.23542606283924014,-0.6417070956037559,0.9598347398148359,0.5283374011848795,-0.8605609719945663,-0.24300698162028928,-0.33417242136584113,0.087264561932277,-0.002206819462379813,-0.24300698162028928,0.730826559921213,-0.8291051207987041,0.2649184437199032,1.0167021690167521,-0.182497206611748,0.17630258634391707,-0.5797340545401417,0.9028157215260153,0.29436510731780724,0.2649184437199032,0.29436510731780724,0.17630258634391707,-0.002206819462379813,-0.09212329847709767,1.4385861401124023,0.6731783026903564,0.05748948699344504
2,448
Cell cortex
18
74
2.202253
0.027647
Q13363,P15311,P09497,Q8TAG9,Q01518,P41440,Q14847,Q14203,P35241,Q14019,O00471,Q9NQW6,Q15691,Q02952,P17655,P61586,P35609,Q96J02
Localization
GO Cellular component
msigdb_gocc
32,432,411,37,294,71,138,262,415,137,110,320,112,86,367,25,434,126
110,1614,1259,1403,1260,952,1681,1618,1767,1770,1048,955,411,819,684,432,367,1453,1266,1005,616,1407,415,523,593,434,71,2041,964,1627,1180,1061,1731,1997,836,25,2361,1587,879,294,86,1019,440,1590,702,32,842,137,262,881,574,1631,2188,138,1592,1422,112,977,1152,1027,752,37,854,2081,126,320,760,1086,1296,763,587,1297,1642,1346
1.3548410508645194,-0.30372981581819986,-0.06210093493456228,-0.15232095828757117,-0.06210093493456228,0.14667069399718627,-0.364669859579678,-0.30372981581819986,-0.42583141250889395,-0.42583141250889395,0.087264561932277,0.14667069399718627,0.5863988415320117,0.23542606283924014,0.3237664369124269,0.5573891868193322,0.6442930758559092,-0.182497206611748,-0.06210093493456228,0.11699149062391306,0.38243459835151017,-0.15232095828757117,0.5863988415320117,0.47010609080532134,0.4117021682718201,0.5573891868193322,1.7431006951795138,-0.6727843897556249,0.14667069399718627,-0.30372981581819986,-0.002206819462379813,0.087264561932277,-0.3952226726312979,-0.6106905307608944,0.23542606283924014,2.581598099731636,-1.2757154640498929,-0.27334151033073334,0.2058875754695338,0.7595902108481608,1.5774902044257157,0.11699149062391306,0.5573891868193322,-0.27334151033073334,0.3237664369124269,2.474919285820168,0.23542606283924014,1.2426985519939489,0.8169980768047461,0.2058875754695338,0.4409258805823772,-0.30372981581819986,-0.8291051207987041,1.2426985519939489,-0.27334151033073334,-0.15232095828757117,1.3548410508645194,0.14667069399718627,0.027665838086341914,0.11699149062391306,0.29436510731780724,2.206322562220572,0.23542606283924014,-0.7039230664205183,1.298839486996753,0.730826559921213,0.29436510731780724,0.087264561932277,-0.06210093493456228,0.29436510731780724,0.4409258805823772,-0.06210093493456228,-0.30372981581819986,-0.09212329847709767
2,448
Positive regulation of cell differentiation
24
94
2.190305
0.028502
Q8WUJ1,Q9UQB8,Q9Y624,P78344,P04083,P04179,O14786,Q99873,Q04637,P61586,O60271,Q86X55,Q9UPY3,Q15014,Q96A49,Q9H3U1,P50570,Q92766,Q99829,P27695,P40763,P17931,O14744,Q15418
Processes and pathways
GO Biological process
msigdb_gobp
1,134,405,529,15,142,508,283,278,25,408,445,60,63,353,355,469,351,233,344,241,368,237,489
1168,1042,1400,237,508,2091,509,2173,1445,408,1486,1952,1835,648,1573,1684,733,15,142,734,1532,1172,653,1049,1097,685,1174,2039,368,1005,773,344,1137,657,1407,1365,241,1270,1408,1776,1318,469,1227,742,1369,595,25,529,1416,2152,786,278,1146,923,747,1378,704,789,790,1592,63,489,793,2311,1152,1028,445,1,351,1289,983,353,2081,2134,1669,233,283,1337,1252,802,2327,892,355,2033,2108,941,1561,2089,2264,60,1167,134,405,1525
-0.002206819462379813,0.087264561932277,-0.15232095828757117,0.8742486728862037,0.47010609080532134,-0.7351237916771668,0.47010609080532134,-0.8291051207987041,-0.182497206611748,0.5863988415320117,-0.21272571549189503,-0.5797340545401417,-0.4872189313453426,0.3531228099863507,-0.27334151033073334,-0.364669859579678,0.29436510731780724,4.161025061636598,1.2145752253051996,0.29436510731780724,-0.24300698162028928,-0.002206819462379813,0.3531228099863507,0.087264561932277,0.05748948699344504,0.3237664369124269,-0.002206819462379813,-0.6727843897556249,0.6442930758559092,0.11699149062391306,0.2649184437199032,0.6731783026903564,0.027665838086341914,0.3531228099863507,-0.15232095828757117,-0.12219648225605645,0.8742486728862037,-0.06210093493456228,-0.15232095828757117,-0.42583141250889395,-0.09212329847709767,0.5283374011848795,-0.03212892744333096,0.29436510731780724,-0.12219648225605645,0.4117021682718201,2.581598099731636,0.47010609080532134,-0.15232095828757117,-0.7977141188950565,0.2649184437199032,0.7883139498979853,0.027665838086341914,0.17630258634391707,0.29436510731780724,-0.12219648225605645,0.3237664369124269,0.2649184437199032,0.2649184437199032,-0.27334151033073334,1.798050804303417,0.4992431492624739,0.2649184437199032,-1.0507002473854663,0.027665838086341914,0.11699149062391306,0.5573891868193322,8.218958800035029,0.6731783026903564,-0.06210093493456228,0.14667069399718627,0.6731783026903564,-0.7039230664205183,-0.7663872448501347,-0.33417242136584113,0.9028157215260153,0.7883139498979853,-0.09212329847709767,-0.03212892744333096,0.2649184437199032,-1.114634054017247,0.2058875754695338,0.6731783026903564,-0.6417070956037559,-0.7351237916771668,0.17630258634391707,-0.24300698162028928,-0.7039230664205183,-0.9236701828387313,1.825479230161245,0.027665838086341914,1.2707865591544374,0.615366695909301,-0.21272571549189503
2,448
Zinc finger, RING-type [IPR001841]
10
19
2.182344
0.029084
Q7Z6E9,Q9Y4X5,Q96T88,Q99590,Q12899,P19474,O75592,Q13263,Q5VTR2,Q14258
Sequence
InterPro Domain
interpro_domain
395,178,499,47,486,18,219,487,443,442
950,219,1490,1685,2038,18,1011,486,487,442,975,443,395,499,47,2138,546,178,943
0.14667069399718627,0.9313443171057458,-0.21272571549189503,-0.364669859579678,-0.6727843897556249,3.7035378773687953,0.11699149062391306,0.4992431492624739,0.4992431492624739,0.5573891868193322,0.14667069399718627,0.5573891868193322,0.615366695909301,0.4992431492624739,1.9348864822376677,-0.7663872448501347,0.47010609080532134,1.0734201781652684,0.17630258634391707
2,448
G2 m checkpoints
35
74
2.180813
0.029197
Q9UQ84,P51530,P48556,Q9NXR7,Q13200,Q92547,P25789,P27694,Q04917,P33991,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,P14635,Q99436,P06493,P35998,P51665,P15927,P33993,P63104,P62191,P20618,O43242,O14818,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
10,261,260,146,390,157,275,655,572,658,291,167,581,49,51,588,54,724,550,555,69,683,691,77,251,592,698,697,220,227,730,484,488,531,397
550,946,1766,730,227,1913,2357,1872,1684,1685,2203,683,555,251,1003,1052,220,738,1310,291,1268,275,1311,655,1727,54,49,51,1455,658,1497,592,1960,1498,691,1011,963,1650,260,1728,167,1060,1653,261,77,2069,1102,484,782,969,783,697,1503,1586,1463,2332,698,572,531,1811,390,1074,1850,488,397,157,1333,69,581,1161,146,588,724,10
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5488370384270144,-1.2757154640498929,-0.5179988657470733,-0.364669859579678,-0.364669859579678,-0.8605609719945663,0.3237664369124269,0.4409258805823772,0.8456428872388043,0.11699149062391306,0.087264561932277,0.9313443171057458,0.29436510731780724,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.09212329847709767,0.3531228099863507,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.182497206611748,0.3531228099863507,-0.21272571549189503,0.4117021682718201,-0.5797340545401417,-0.21272571549189503,0.3237664369124269,0.11699149062391306,0.14667069399718627,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,0.087264561932277,-0.33417242136584113,0.8169980768047461,1.6880249517622525,-0.7039230664205183,0.05748948699344504,0.4992431492624739,0.2649184437199032,0.14667069399718627,0.2649184437199032,0.3237664369124269,-0.21272571549189503,-0.27334151033073334,-0.182497206611748,-1.1467083845303592,0.3237664369124269,0.4409258805823772,0.47010609080532134,-0.4564966412770062,0.615366695909301,0.087264561932277,-0.4872189313453426,0.4992431492624739,0.615366695909301,1.1582216374253231,-0.09212329847709767,1.7705913566526543,0.4409258805823772,0.027665838086341914,1.2145752253051996,0.4409258805823772,0.3237664369124269,4.66189423786694
2,448
transporter
11
52
2.176319
0.029531
Q8TEX9,O43772,Q92973,P41440,Q9H2D1,Q567V2,Q8NFH4,Q6N075,Q9NR77,O60830,O60684
Functions
Panther Protein class
panther_protein_class
265,5,266,71,234,44,114,52,59,27,250
606,1348,1949,1400,1401,811,2058,1091,5,250,27,1448,511,1499,71,563,1272,1182,1320,1655,2255,2208,622,569,1231,970,315,1506,705,44,52,796,885,114,1554,265,266,1938,1117,1199,2408,1158,2402,2009,234,803,2382,59,1344,990,1440,1722
0.38243459835151017,-0.12219648225605645,-0.5797340545401417,-0.15232095828757117,-0.15232095828757117,0.23542606283924014,-0.7039230664205183,0.05748948699344504,5.955555663780612,0.8456428872388043,2.5283117833572146,-0.182497206611748,0.47010609080532134,-0.21272571549189503,1.7431006951795138,0.4409258805823772,-0.06210093493456228,-0.002206819462379813,-0.09212329847709767,-0.33417242136584113,-0.9236701828387313,-0.8605609719945663,0.38243459835151017,0.4409258805823772,-0.03212892744333096,0.14667069399718627,0.730826559921213,-0.21272571549189503,0.3237664369124269,1.9621626060274844,1.88024377397462,0.2649184437199032,0.2058875754695338,1.3548410508645194,-0.24300698162028928,0.8169980768047461,0.8169980768047461,-0.5488370384270144,0.05748948699344504,-0.002206819462379813,-1.7357819422386331,0.027665838086341914,-1.6692746780999153,-0.6106905307608944,0.9028157215260153,0.2649184437199032,-1.43853216506728,1.825479230161245,-0.09212329847709767,0.14667069399718627,-0.15232095828757117,-0.364669859579678
2,448
Negative regulation of developmental process
26
85
2.175143
0.029619
Q96T37,Q8N4Q0,P04179,P04083,Q99873,P61586,Q06124,P14174,O60271,P26196,Q8WX92,Q6PD62,Q9UPY3,P16989,Q13247,Q92688,Q9NYV4,Q9P258,Q96G23,P11413,Q9Y5A9,Q8N0X7,P40763,Q00535,O14744,O15347
Processes and pathways
GO Biological process
msigdb_gobp
267,12,142,15,283,25,295,35,408,412,50,58,60,70,73,213,359,360,93,342,236,373,241,370,237,248
237,508,248,1259,408,1351,1874,1304,2385,15,142,2203,2430,1769,734,552,653,342,957,35,70,412,1099,1493,1137,1494,657,1139,913,1407,2207,241,1270,695,1318,1925,437,25,2332,528,878,370,2152,572,295,2354,2333,923,73,1507,747,789,2157,2105,793,1191,750,58,634,445,373,12,1551,2050,50,213,1289,577,2081,1516,93,267,2318,801,2217,283,1339,2356,1478,2031,359,360,1297,60,236
0.8742486728862037,0.47010609080532134,0.8456428872388043,-0.06210093493456228,0.5863988415320117,-0.12219648225605645,-0.5179988657470733,-0.09212329847709767,-1.504130786089521,4.161025061636598,1.2145752253051996,-0.8605609719945663,-3.0085610162180214,-0.42583141250889395,0.29436510731780724,0.4409258805823772,0.3531228099863507,0.6731783026903564,0.14667069399718627,2.3409658129140403,1.7431006951795138,0.5863988415320117,0.05748948699344504,-0.21272571549189503,0.027665838086341914,-0.21272571549189503,0.3531228099863507,0.027665838086341914,0.17630258634391707,-0.15232095828757117,-0.8605609719945663,0.8742486728862037,-0.06210093493456228,0.3237664369124269,-0.09212329847709767,-0.5488370384270144,0.5573891868193322,2.581598099731636,-1.1467083845303592,0.47010609080532134,0.2058875754695338,0.6442930758559092,-0.7977141188950565,0.4409258805823772,0.7595902108481608,-1.243358299991923,-1.1467083845303592,0.17630258634391707,1.7431006951795138,-0.21272571549189503,0.29436510731780724,0.2649184437199032,-0.7977141188950565,-0.7351237916771668,0.2649184437199032,-0.002206819462379813,0.29436510731780724,1.825479230161245,0.38243459835151017,0.5573891868193322,0.6442930758559092,4.437434635650035,-0.24300698162028928,-0.6727843897556249,1.9075802654498024,0.9598347398148359,-0.06210093493456228,0.4409258805823772,-0.7039230664205183,-0.21272571549189503,1.4942473318432876,0.8169980768047461,-1.0826315524646415,0.2649184437199032,-0.8605609719945663,0.7883139498979853,-0.09212329847709767,-1.243358299991923,-0.182497206611748,-0.6417070956037559,0.6731783026903564,0.6731783026903564,-0.06210093493456228,1.825479230161245,0.9028157215260153
2,448
Positive regulation of calcium ion transport
8
12
2.155552
0.031119
P11413,P27695,P30626,P17931,P0DP25,Q00535,P54652,P28161
Processes and pathways
GO Biological process
msigdb_gobp
342,344,413,368,240,370,311,116
1687,240,342,368,1625,344,116,413,311,920,370,485
-0.364669859579678,0.8742486728862037,0.6731783026903564,0.6442930758559092,-0.30372981581819986,0.6731783026903564,1.3268575727799916,0.5863988415320117,0.730826559921213,0.17630258634391707,0.6442930758559092,0.4992431492624739
2,448
Transcriptional regulation by runx1
25
63
2.154747
0.031182
Q92530,P48556,Q99873,Q12824,Q13200,P25789,Q06124,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,O15047,Q99436,P61964,P51665,P20618,O43242,P17931,P60900,Q15008,Q06323,Q96J02
Processes and pathways
Reactome Pathways
msigdb_reactome
397,260,283,417,390,275,295,291,167,581,49,51,588,54,61,69,67,77,220,227,368,484,488,531,126
550,946,1766,1043,730,61,227,1872,2110,1003,368,1052,1582,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,1807,77,1102,484,969,67,697,1503,1463,2332,1698,2024,295,531,1235,417,390,747,789,488,1547,2275,1595,397,2235,1597,1973,126,2134,69,581,283,1203,2283,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.087264561932277,0.29436510731780724,1.798050804303417,0.9028157215260153,-0.5179988657470733,-0.7663872448501347,0.11699149062391306,0.6442930758559092,0.087264561932277,-0.27334151033073334,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,-0.4564966412770062,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.14667069399718627,1.7705913566526543,0.3237664369124269,-0.21272571549189503,-0.182497206611748,-1.1467083845303592,-0.364669859579678,-0.6417070956037559,0.7595902108481608,0.47010609080532134,-0.03212892744333096,0.5863988415320117,0.615366695909301,0.29436510731780724,0.2649184437199032,0.4992431492624739,-0.24300698162028928,-0.9553250615605502,-0.27334151033073334,0.615366695909301,-0.8920824087947153,-0.27334151033073334,-0.5797340545401417,1.298839486996753,-0.7663872448501347,1.7705913566526543,0.4409258805823772,0.7883139498979853,-0.002206819462379813,-0.9553250615605502,0.4409258805823772,0.3237664369124269
2,448
Positive regulation of calcium ion transmembrane transport
7
10
2.147974
0.031716
P11413,P27695,P30626,P0DP25,Q00535,P54652,P28161
Processes and pathways
GO Biological process
msigdb_gobp
342,344,413,240,370,311,116
1687,240,342,344,116,413,311,920,370,485
-0.364669859579678,0.8742486728862037,0.6731783026903564,0.6731783026903564,1.3268575727799916,0.5863988415320117,0.730826559921213,0.17630258634391707,0.6442930758559092,0.4992431492624739
2,448
Contractile fiber
17
42
2.145711
0.031896
Q8WX93,Q9NYL9,P04792,Q9Y281,Q9Y376,P30626,P49257,Q05682,Q96HC4,P18206,Q9UJW0,Q14331,P60900,P0DP25,O00151,Q16637,P35609
Localization
GO Cellular component
msigdb_gocc
162,401,6,204,170,413,564,440,580,614,587,471,484,240,428,156,434
428,1259,952,1873,1618,1724,6,1770,1305,240,684,1580,614,1005,413,1407,434,1839,1180,564,779,484,879,1019,440,1376,1147,1377,2025,1073,471,665,156,162,2081,580,401,587,1297,1720,204,170
0.5573891868193322,-0.06210093493456228,0.14667069399718627,-0.5179988657470733,-0.30372981581819986,-0.3952226726312979,5.931560240339164,-0.42583141250889395,-0.09212329847709767,0.8742486728862037,0.3237664369124269,-0.27334151033073334,0.38243459835151017,0.11699149062391306,0.5863988415320117,-0.15232095828757117,0.5573891868193322,-0.4872189313453426,-0.002206819462379813,0.4409258805823772,0.2649184437199032,0.4992431492624739,0.2058875754695338,0.11699149062391306,0.5573891868193322,-0.12219648225605645,0.027665838086341914,-0.12219648225605645,-0.6417070956037559,0.087264561932277,0.5283374011848795,0.3531228099863507,1.1582216374253231,1.1299908805711318,-0.7039230664205183,0.4409258805823772,0.615366695909301,0.4409258805823772,-0.06210093493456228,-0.364669859579678,0.9882872661563274,1.1017238127490079
2,448
FDA approved drug targets
14
96
2.141211
0.032257
Q99720,P02656,P48735,O75874,Q99707,P49721,P20645,P04083,P49354,P28074,P38435,P20618,Q14353,Q16637
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
65,2,3,7,168,167,14,15,242,51,180,220,57,156
1401,249,7,382,383,1217,733,1263,2,2385,15,481,2142,2143,2430,1531,2175,1769,1620,1771,1132,1355,1049,464,2386,2112,2268,366,613,2095,956,1098,1772,684,1175,823,1838,824,2353,1625,220,14,343,1406,1053,2179,826,2248,688,1099,1221,912,51,1494,2225,2330,2098,2270,520,1648,1010,180,1693,2331,1408,1271,3,1013,242,167,2253,917,568,437,699,2123,786,2287,598,2104,1507,747,57,2213,2076,1784,156,2106,882,1663,1856,1289,168,2338,65,547
-0.15232095828757117,0.8456428872388043,5.594030281929976,0.615366695909301,0.615366695909301,-0.03212892744333096,0.29436510731780724,-0.06210093493456228,6.997268324204374,-1.504130786089521,4.161025061636598,0.4992431492624739,-0.7977141188950565,-0.7977141188950565,-3.0085610162180214,-0.24300698162028928,-0.8291051207987041,-0.42583141250889395,-0.30372981581819986,-0.42583141250889395,0.027665838086341914,-0.12219648225605645,0.087264561932277,0.5283374011848795,-1.504130786089521,-0.7663872448501347,-0.9553250615605502,0.6442930758559092,0.38243459835151017,-0.7351237916771668,0.14667069399718627,0.05748948699344504,-0.42583141250889395,0.3237664369124269,-0.002206819462379813,0.23542606283924014,-0.4872189313453426,0.23542606283924014,-1.243358299991923,-0.30372981581819986,0.9313443171057458,4.186249780581747,0.6731783026903564,-0.15232095828757117,0.087264561932277,-0.8291051207987041,0.23542606283924014,-0.9236701828387313,0.3237664369124269,0.05748948699344504,-0.03212892744333096,0.17630258634391707,1.88024377397462,-0.21272571549189503,-0.8920824087947153,-1.1467083845303592,-0.7351237916771668,-0.9553250615605502,0.47010609080532134,-0.33417242136584113,0.11699149062391306,1.0450797177342925,-0.364669859579678,-1.1467083845303592,-0.15232095828757117,-0.06210093493456228,6.432398994236586,0.11699149062391306,0.8742486728862037,1.1017238127490079,-0.9236701828387313,0.17630258634391707,0.4409258805823772,0.5573891868193322,0.3237664369124269,-0.7663872448501347,0.2649184437199032,-0.987047828674115,0.4117021682718201,-0.7351237916771668,-0.21272571549189503,0.29436510731780724,1.825479230161245,-0.8605609719945663,-0.7039230664205183,-0.42583141250889395,1.1582216374253231,-0.7351237916771668,0.2058875754695338,-0.33417242136584113,-0.4872189313453426,-0.06210093493456228,1.1017238127490079,-1.1467083845303592,1.798050804303417,0.47010609080532134
2,448
FDA approved drug targets
14
96
2.141211
0.032257
Q99720,P02656,P48735,O75874,Q99707,P49721,P20645,P04083,P49354,P28074,P38435,P20618,Q14353,Q16637
Functions
Protein Atlas Protein class
protein_atlas_protein_class
65,2,3,7,168,167,14,15,242,51,180,220,57,156
1401,249,7,382,383,1217,733,1263,2,2385,15,481,2142,2143,2430,1531,2175,1769,1620,1771,1132,1355,1049,464,2386,2112,2268,366,613,2095,956,1098,1772,684,1175,823,1838,824,2353,1625,220,14,343,1406,1053,2179,826,2248,688,1099,1221,912,51,1494,2225,2330,2098,2270,520,1648,1010,180,1693,2331,1408,1271,3,1013,242,167,2253,917,568,437,699,2123,786,2287,598,2104,1507,747,57,2213,2076,1784,156,2106,882,1663,1856,1289,168,2338,65,547
-0.15232095828757117,0.8456428872388043,5.594030281929976,0.615366695909301,0.615366695909301,-0.03212892744333096,0.29436510731780724,-0.06210093493456228,6.997268324204374,-1.504130786089521,4.161025061636598,0.4992431492624739,-0.7977141188950565,-0.7977141188950565,-3.0085610162180214,-0.24300698162028928,-0.8291051207987041,-0.42583141250889395,-0.30372981581819986,-0.42583141250889395,0.027665838086341914,-0.12219648225605645,0.087264561932277,0.5283374011848795,-1.504130786089521,-0.7663872448501347,-0.9553250615605502,0.6442930758559092,0.38243459835151017,-0.7351237916771668,0.14667069399718627,0.05748948699344504,-0.42583141250889395,0.3237664369124269,-0.002206819462379813,0.23542606283924014,-0.4872189313453426,0.23542606283924014,-1.243358299991923,-0.30372981581819986,0.9313443171057458,4.186249780581747,0.6731783026903564,-0.15232095828757117,0.087264561932277,-0.8291051207987041,0.23542606283924014,-0.9236701828387313,0.3237664369124269,0.05748948699344504,-0.03212892744333096,0.17630258634391707,1.88024377397462,-0.21272571549189503,-0.8920824087947153,-1.1467083845303592,-0.7351237916771668,-0.9553250615605502,0.47010609080532134,-0.33417242136584113,0.11699149062391306,1.0450797177342925,-0.364669859579678,-1.1467083845303592,-0.15232095828757117,-0.06210093493456228,6.432398994236586,0.11699149062391306,0.8742486728862037,1.1017238127490079,-0.9236701828387313,0.17630258634391707,0.4409258805823772,0.5573891868193322,0.3237664369124269,-0.7663872448501347,0.2649184437199032,-0.987047828674115,0.4117021682718201,-0.7351237916771668,-0.21272571549189503,0.29436510731780724,1.825479230161245,-0.8605609719945663,-0.7039230664205183,-0.42583141250889395,1.1582216374253231,-0.7351237916771668,0.2058875754695338,-0.33417242136584113,-0.4872189313453426,-0.06210093493456228,1.1017238127490079,-1.1467083845303592,1.798050804303417,0.47010609080532134
2,448
Guanyl nucleotide exchange factor activity
11
23
2.115066
0.034424
Q9NWX6,P18085,P29692,P80303,Q9UI10,Q9NR50,Q15042,Q02818,Q9Y2L1,Q9P258,O75592
Functions
GO Molecular function
msigdb_gomf
102,433,292,107,379,245,209,182,427,360,219
219,433,2114,466,292,1695,107,182,1417,1150,2212,706,209,633,797,983,1432,1204,245,102,360,379,427
0.9313443171057458,0.5573891868193322,-0.7663872448501347,0.5283374011848795,0.7595902108481608,-0.364669859579678,1.3827901527630164,1.0450797177342925,-0.15232095828757117,0.027665838086341914,-0.8605609719945663,0.3237664369124269,0.9598347398148359,0.38243459835151017,0.2649184437199032,0.14667069399718627,-0.15232095828757117,-0.002206819462379813,0.8742486728862037,1.4385861401124023,0.6731783026903564,0.6442930758559092,0.5863988415320117
2,448
Negative regulation of immune system process
7
36
2.110437
0.034821
P14174,Q9Y5A9,P04083,P19474,P28070,Q5JRA6,Q96J02
Processes and pathways
GO Biological process
msigdb_gobp
35,236,15,18,54,28,126
248,2375,1835,1170,15,1575,653,2144,654,35,2038,432,368,18,1310,54,617,1139,1407,2207,619,525,2070,1845,789,2072,927,2311,28,933,1516,126,1295,1127,1209,236
0.8456428872388043,-1.4058330257519098,-0.4872189313453426,-0.002206819462379813,4.161025061636598,-0.27334151033073334,0.3531228099863507,-0.7977141188950565,0.3531228099863507,2.3409658129140403,-0.6727843897556249,0.5573891868193322,0.6442930758559092,3.7035378773687953,-0.09212329847709767,1.8528768241204838,0.38243459835151017,0.027665838086341914,-0.15232095828757117,-0.8605609719945663,0.38243459835151017,0.47010609080532134,-0.7039230664205183,-0.4872189313453426,0.2649184437199032,-0.7039230664205183,0.17630258634391707,-1.0507002473854663,2.5283117833572146,0.17630258634391707,-0.21272571549189503,1.298839486996753,-0.06210093493456228,0.05748948699344504,-0.002206819462379813,0.9028157215260153
2,448
Interleukin 1 family signaling
21
47
2.103003
0.035466
P48556,Q13200,P25789,Q06124,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q99436,P63208,P51665,P20618,O43242,P40763,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,275,295,291,167,581,49,51,588,54,69,439,77,220,227,241,484,488,531,397
550,946,1766,730,227,1872,2430,653,1052,220,1310,291,1268,275,1727,54,49,51,691,241,1650,260,1728,167,77,1102,484,782,969,697,1503,1463,439,786,295,531,390,2025,1109,488,1469,397,69,581,937,588,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.5179988657470733,-3.0085610162180214,0.3531228099863507,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,0.8742486728862037,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,1.6880249517622525,0.05748948699344504,0.4992431492624739,0.2649184437199032,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.5573891868193322,0.2649184437199032,0.7595902108481608,0.47010609080532134,0.615366695909301,-0.6417070956037559,0.05748948699344504,0.4992431492624739,-0.182497206611748,0.615366695909301,1.7705913566526543,0.4409258805823772,0.17630258634391707,0.4409258805823772,0.3237664369124269
2,448
Cell projection organization
69
178
2.093372
0.036316
Q9NT62,Q9UQB8,Q15428,Q14203,O60828,P78344,O60749,P00374,P16949,O14786,O15144,Q99873,P61586,P08670,P11233,P33176,Q06124,P35579,Q8TEY7,Q8WX93,A6NIH7,Q15555,Q04917,O60271,Q14247,Q99707,P35241,Q9BUP0,Q9BW83,Q86X55,Q9NQW6,Q8NCA5,Q9Y296,Q9UPY3,Q9NR77,Q8TC07,A0AVT1,P35609,O95372,Q02790,P55145,P15311,P18085,P61964,Q9Y5Y2,P41440,Q9H4M9,P51116,P35613,Q9H223,Q9UBB4,O14745,P50570,Q9P258,O60678,O75592,Q96G23,Q92766,Q9Y5K6,Q99829,P27695,P20339,O95684,P11047,O00471,Q15691,Q8N0X7,Q00535,O75312
Processes and pathways
GO Biological process
msigdb_gobp
128,134,139,262,259,529,258,383,384,508,509,283,25,515,517,522,295,523,300,162,36,296,572,408,574,168,415,583,45,445,320,447,454,60,59,186,302,434,307,193,191,432,433,67,205,71,333,436,76,214,479,207,469,360,218,219,93,351,362,233,344,230,228,229,110,112,373,370,363
302,36,1211,110,2139,207,508,2091,1678,509,904,408,1486,1446,218,258,259,363,219,1681,1835,307,228,1001,383,1263,2369,2430,1769,734,1048,1002,1172,515,653,1264,736,229,517,432,384,433,614,1453,230,1005,1267,344,912,657,522,2021,913,1407,415,523,434,76,1583,71,1408,2065,1776,964,1180,1318,1100,469,779,436,1925,191,595,1963,744,1880,1183,25,67,1882,2361,529,1233,1587,370,786,193,2287,572,295,2333,1544,1068,1147,1377,626,1781,1507,925,663,1702,1591,2428,2072,262,574,790,2188,1422,139,296,112,977,1470,667,1152,1027,795,979,1111,1028,445,670,373,447,186,300,1115,162,797,351,1289,2193,855,93,580,1432,2279,719,2134,2217,168,233,283,985,583,2351,1900,45,214,2327,892,333,1203,2031,320,59,128,2088,1638,1639,360,479,2340,763,1561,1297,1124,2264,60,134,2265,454,808,1609,1908,362,205
0.730826559921213,2.314092963919821,-0.03212892744333096,1.3548410508645194,-0.7977141188950565,0.9598347398148359,0.47010609080532134,-0.7351237916771668,-0.364669859579678,0.47010609080532134,0.17630258634391707,0.5863988415320117,-0.21272571549189503,-0.182497206611748,0.9313443171057458,0.8169980768047461,0.8169980768047461,0.6442930758559092,0.9313443171057458,-0.364669859579678,-0.4872189313453426,0.730826559921213,0.9028157215260153,0.11699149062391306,0.615366695909301,-0.06210093493456228,-1.3406374671292853,-3.0085610162180214,-0.42583141250889395,0.29436510731780724,0.087264561932277,0.11699149062391306,-0.002206819462379813,0.47010609080532134,0.3531228099863507,-0.06210093493456228,0.29436510731780724,0.9028157215260153,0.47010609080532134,0.5573891868193322,0.615366695909301,0.5573891868193322,0.38243459835151017,-0.182497206611748,0.9028157215260153,0.11699149062391306,-0.06210093493456228,0.6731783026903564,0.17630258634391707,0.3531228099863507,0.47010609080532134,-0.6417070956037559,0.17630258634391707,-0.15232095828757117,0.5863988415320117,0.47010609080532134,0.5573891868193322,1.6880249517622525,-0.27334151033073334,1.7431006951795138,-0.15232095828757117,-0.7039230664205183,-0.42583141250889395,0.14667069399718627,-0.002206819462379813,-0.09212329847709767,0.05748948699344504,0.5283374011848795,0.2649184437199032,0.5573891868193322,-0.5488370384270144,1.0167021690167521,0.4117021682718201,-0.5797340545401417,0.29436510731780724,-0.5179988657470733,-0.002206819462379813,2.581598099731636,1.7705913566526543,-0.5179988657470733,-1.2757154640498929,0.47010609080532134,-0.03212892744333096,-0.27334151033073334,0.6442930758559092,0.2649184437199032,1.0167021690167521,-0.987047828674115,0.4409258805823772,0.7595902108481608,-1.1467083845303592,-0.24300698162028928,0.087264561932277,0.027665838086341914,-0.12219648225605645,0.38243459835151017,-0.42583141250889395,-0.21272571549189503,0.17630258634391707,0.3531228099863507,-0.364669859579678,-0.27334151033073334,-2.937845643123165,-0.7039230664205183,0.8169980768047461,0.4409258805823772,0.2649184437199032,-0.8291051207987041,-0.15232095828757117,1.2426985519939489,0.7595902108481608,1.3548410508645194,0.14667069399718627,-0.182497206611748,0.3531228099863507,0.027665838086341914,0.11699149062391306,0.2649184437199032,0.14667069399718627,0.05748948699344504,0.11699149062391306,0.5573891868193322,0.3531228099863507,0.6442930758559092,0.5573891868193322,1.0450797177342925,0.7595902108481608,0.05748948699344504,1.1299908805711318,0.2649184437199032,0.6731783026903564,-0.06210093493456228,-0.8291051207987041,0.23542606283924014,1.4942473318432876,0.4409258805823772,-0.15232095828757117,-0.9553250615605502,0.3237664369124269,-0.7663872448501347,-0.8605609719945663,1.1017238127490079,0.9028157215260153,0.7883139498979853,0.14667069399718627,0.4409258805823772,-1.211071046856623,-0.5179988657470733,1.9621626060274844,0.9598347398148359,-1.114634054017247,0.2058875754695338,0.7020226932379363,-0.002206819462379813,-0.6417070956037559,0.730826559921213,1.825479230161245,1.298839486996753,-0.7039230664205183,-0.30372981581819986,-0.30372981581819986,0.6731783026903564,0.5283374011848795,-1.1467083845303592,0.29436510731780724,-0.24300698162028928,-0.06210093493456228,0.05748948699344504,-0.9236701828387313,1.825479230161245,1.2707865591544374,-0.9236701828387313,0.5573891868193322,0.2649184437199032,-0.27334151033073334,-0.5179988657470733,0.6731783026903564,0.9882872661563274
2,448
Cis trans isomerase activity
6
20
2.093287
0.036324
Q9H2H8,Q13526,Q15257,Q96AY3,Q9Y3C6,Q02790
Functions
GO Molecular function
msigdb_gomf
96,175,55,26,195,193
1041,1679,2019,468,2098,1496,914,1729,972,193,1465,232,175,2187,55,1243,26,96,2034,195
0.087264561932277,-0.364669859579678,-0.6417070956037559,0.5283374011848795,-0.7351237916771668,-0.21272571549189503,0.17630258634391707,-0.3952226726312979,0.14667069399718627,1.0167021690167521,-0.182497206611748,0.9028157215260153,1.0734201781652684,-0.8291051207987041,1.8528768241204838,-0.03212892744333096,2.5549681424265085,1.4664334747935266,-0.6417070956037559,1.0167021690167521
2,448
Protein peptidyl prolyl isomerization
6
20
2.093287
0.036324
Q9H2H8,Q13526,Q15257,Q96AY3,Q9Y3C6,Q02790
Processes and pathways
GO Biological process
msigdb_gobp
96,175,55,26,195,193
1041,1679,2019,468,2098,1496,914,1729,972,193,1465,232,175,2187,55,1243,26,96,2034,195
0.087264561932277,-0.364669859579678,-0.6417070956037559,0.5283374011848795,-0.7351237916771668,-0.21272571549189503,0.17630258634391707,-0.3952226726312979,0.14667069399718627,1.0167021690167521,-0.182497206611748,0.9028157215260153,1.0734201781652684,-0.8291051207987041,1.8528768241204838,-0.03212892744333096,2.5549681424265085,1.4664334747935266,-0.6417070956037559,1.0167021690167521
2,448
S adenosylmethionine dependent methyltransferase activity
13
36
2.090155
0.036604
P61964,Q9H9B1,O14744,O60678,P57081,O75648,Q08J23,Q99873,Q7L2J0,Q9H7B4,Q14353,Q9BV44,O15047
Functions
GO Molecular function
msigdb_gomf
67,335,237,218,174,381,389,283,151,24,57,188,61
237,61,949,812,218,1616,381,1685,1053,2018,1099,2182,174,67,2024,389,927,57,1077,1547,1745,1283,151,445,1709,1594,1556,1712,2337,283,188,24,501,335,2283,1397
0.8742486728862037,1.798050804303417,0.14667069399718627,0.23542606283924014,0.9313443171057458,-0.30372981581819986,0.615366695909301,-0.364669859579678,0.087264561932277,-0.6417070956037559,0.05748948699344504,-0.8291051207987041,1.0734201781652684,1.7705913566526543,-0.6417070956037559,0.615366695909301,0.17630258634391707,1.825479230161245,0.087264561932277,-0.24300698162028928,-0.3952226726312979,-0.06210093493456228,1.1864163358736073,0.5573891868193322,-0.364669859579678,-0.27334151033073334,-0.24300698162028928,-0.364669859579678,-1.1467083845303592,0.7883139498979853,1.0450797177342925,2.7408312506583243,0.4992431492624739,0.7020226932379363,-0.9553250615605502,-0.12219648225605645
2,448
Nuclear bodies
16
89
2.078015
0.037708
Q69YN4,Q99436,Q9BTY7,Q9H9B1,O75874,O75153,Q9UQ84,Q9BXJ9,Q99590,Q9BXW9,Q9H3P2,P61081,Q92547,O00178,Q16637,P15927
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
349,69,201,335,7,9,10,255,47,244,284,314,157,56,156,251
1566,1040,1611,56,607,1800,1259,1445,9,998,7,1530,1989,735,1173,819,251,1052,1310,1454,690,1223,523,1773,1011,1316,743,1016,1809,314,2396,2361,921,531,1811,1107,347,2125,442,1190,1850,2157,844,2126,2105,709,1470,156,1934,349,2344,444,1708,1330,1242,157,1290,1291,2302,1157,1390,603,1601,69,47,201,2010,255,244,1160,2421,284,501,335,1604,1437,1206,805,2168,895,1121,678,10,1300,1721,1208,863,1209,1345
-0.27334151033073334,0.087264561932277,-0.30372981581819986,1.825479230161245,0.38243459835151017,-0.4564966412770062,-0.06210093493456228,-0.182497206611748,5.057346280317093,0.11699149062391306,5.594030281929976,-0.24300698162028928,-0.6106905307608944,0.29436510731780724,-0.002206819462379813,0.23542606283924014,0.8456428872388043,0.087264561932277,-0.09212329847709767,-0.182497206611748,0.3237664369124269,-0.03212892744333096,0.47010609080532134,-0.42583141250889395,0.11699149062391306,-0.09212329847709767,0.29436510731780724,0.11699149062391306,-0.4564966412770062,0.730826559921213,-1.603022665769443,-1.2757154640498929,0.17630258634391707,0.47010609080532134,-0.4564966412770062,0.05748948699344504,0.6731783026903564,-0.7663872448501347,0.5573891868193322,-0.002206819462379813,-0.4872189313453426,-0.7977141188950565,0.23542606283924014,-0.7663872448501347,-0.7351237916771668,0.3237664369124269,-0.182497206611748,1.1582216374253231,-0.5488370384270144,0.6731783026903564,-1.1788542301541802,0.5573891868193322,-0.364669859579678,-0.09212329847709767,-0.03212892744333096,1.1582216374253231,-0.06210093493456228,-0.06210093493456228,-1.0188392846787804,0.027665838086341914,-0.12219648225605645,0.4117021682718201,-0.27334151033073334,1.7705913566526543,1.9348864822376677,0.9882872661563274,-0.6106905307608944,0.8456428872388043,0.8742486728862037,0.027665838086341914,-2.4833203972348104,0.7883139498979853,0.4992431492624739,0.7020226932379363,-0.27334151033073334,-0.15232095828757117,-0.002206819462379813,0.2649184437199032,-0.7977141188950565,0.2058875754695338,0.05748948699344504,0.3531228099863507,4.66189423786694,-0.06210093493456228,-0.364669859579678,-0.002206819462379813,0.23542606283924014,-0.002206819462379813,-0.09212329847709767
2,448
protease
14
40
2.072432
0.038225
P61009,Q99436,Q9UNS2,Q9UJ14,P25787,P49721,P48556,O43242,P28072,P28074,Q13200,P28070,P25789,P20618
Functions
Panther Protein class
panther_protein_class
131,69,404,271,291,167,260,227,49,51,390,54,275,220
946,730,227,2383,1953,1052,220,1310,291,1268,275,1727,54,49,51,691,1650,260,1728,167,2254,1102,484,131,697,1503,1463,390,1886,2078,69,581,1159,2241,423,893,271,724,404,1167
0.14667069399718627,0.29436510731780724,0.9028157215260153,-1.4712982411373168,-0.5797340545401417,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.3237664369124269,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,-0.9236701828387313,0.05748948699344504,0.4992431492624739,1.2707865591544374,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.615366695909301,-0.5179988657470733,-0.7039230664205183,1.7705913566526543,0.4409258805823772,0.027665838086341914,-0.8920824087947153,0.5863988415320117,0.2058875754695338,0.8169980768047461,0.3237664369124269,0.615366695909301,0.027665838086341914
2,448
SH3 domain [IPR001452]
6
19
2.067391
0.038697
Q9UQB8,P62993,Q14847,Q9UDY2,Q9NZW5,Q5JRA6
Sequence
InterPro Domain
interpro_domain
134,293,138,46,246,28
1624,831,1776,293,1019,1235,842,574,138,665,28,720,246,46,1124,2264,134,362,1346
-0.30372981581819986,0.23542606283924014,-0.42583141250889395,0.7595902108481608,0.11699149062391306,-0.03212892744333096,0.23542606283924014,0.4409258805823772,1.2426985519939489,0.3531228099863507,2.5283117833572146,0.3237664369124269,0.8742486728862037,1.9621626060274844,0.05748948699344504,-0.9236701828387313,1.2707865591544374,0.6731783026903564,-0.09212329847709767
2,448
Programmed cell death
37
89
2.066681
0.038764
O43633,P48556,Q13200,Q15149,P08670,P25789,P09429,Q04917,Q8WUM4,P49721,P25787,Q9UDY2,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q14974,Q99436,P41440,P35998,P51665,P63104,P20618,O00273,O43242,Q9NR28,Q13177,P49354,P40763,Q07812,P60900,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
130,260,390,665,515,275,653,572,716,167,291,46,581,49,51,588,54,724,550,705,69,71,691,77,698,220,226,227,376,626,242,241,485,484,488,531,397
550,946,226,1347,1766,730,1129,227,130,2036,1872,1681,1574,2203,1989,1002,515,653,1688,1624,1176,2063,1052,220,1004,1310,291,1268,275,1311,1221,1727,54,49,51,1494,875,1455,1407,1365,691,241,71,1650,260,1013,242,1728,167,2286,77,1320,1102,484,969,783,697,1503,1586,1463,698,2361,572,531,1146,1235,485,626,390,1507,842,1736,1631,705,488,665,1382,716,397,2052,69,581,1161,376,46,941,588,1720,724
0.4409258805823772,0.14667069399718627,0.9028157215260153,-0.12219648225605645,-0.42583141250889395,0.29436510731780724,0.027665838086341914,0.9028157215260153,1.2707865591544374,-0.6727843897556249,-0.5179988657470733,-0.364669859579678,-0.27334151033073334,-0.8605609719945663,-0.6106905307608944,0.11699149062391306,0.47010609080532134,0.3531228099863507,-0.364669859579678,-0.30372981581819986,-0.002206819462379813,-0.7039230664205183,0.087264561932277,0.9313443171057458,0.11699149062391306,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.09212329847709767,-0.03212892744333096,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.21272571549189503,0.2058875754695338,-0.182497206611748,-0.15232095828757117,-0.12219648225605645,0.3237664369124269,0.8742486728862037,1.7431006951795138,-0.33417242136584113,0.8169980768047461,0.11699149062391306,0.8742486728862037,-0.3952226726312979,1.1017238127490079,-0.987047828674115,1.6880249517622525,-0.09212329847709767,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.2649184437199032,0.3237664369124269,-0.21272571549189503,-0.27334151033073334,-0.182497206611748,0.3237664369124269,-1.2757154640498929,0.4409258805823772,0.47010609080532134,0.027665838086341914,-0.03212892744333096,0.4992431492624739,0.38243459835151017,0.615366695909301,-0.21272571549189503,0.23542606283924014,-0.3952226726312979,-0.30372981581819986,0.3237664369124269,0.4992431492624739,0.3531228099863507,-0.12219648225605645,0.3237664369124269,0.615366695909301,-0.6727843897556249,1.7705913566526543,0.4409258805823772,0.027665838086341914,0.6442930758559092,1.9621626060274844,0.17630258634391707,0.4409258805823772,-0.364669859579678,0.3237664369124269
2,448
Proteasomal protein catabolic process
42
123
2.065239
0.0389
Q92530,Q16763,P48506,P48556,Q9UJX4,Q13200,Q9BUN8,Q9ULT8,P25789,Q9NXV2,P30260,P25787,P49721,Q9Y4X5,Q99460,P28072,P28074,Q9UBV2,Q9UL46,P28070,Q9NRR5,P54727,Q14258,Q99436,Q9UNZ2,P63208,P46379,P45974,P51665,O15372,Q9Y5K6,P20618,Q93034,Q04323,Q5VYK3,Q9UJX2,P60900,Q15008,Q5TDH0,Q06323,Q96J02,Q14139
Processes and pathways
GO Biological process
msigdb_gobp
397,264,385,260,285,390,159,425,275,31,519,291,167,178,581,49,51,452,588,54,53,312,442,69,203,439,562,561,77,590,362,220,352,111,492,115,484,488,491,531,126,533
1766,730,2091,1044,1401,1129,590,1615,950,1872,1490,648,2017,2369,1172,1097,1690,686,1052,220,1310,291,1268,275,1137,1361,1727,54,49,51,519,1407,691,1650,561,562,385,260,833,1728,167,1318,2286,77,1585,1926,312,1102,1368,1996,1809,484,968,969,697,1503,1463,1415,439,1066,111,531,1544,390,1659,1109,787,1702,1591,533,442,488,1739,2189,709,1324,264,883,491,492,669,634,1330,2005,1969,397,1387,2235,933,1290,352,1245,1749,1860,126,674,69,581,2303,159,802,1940,1477,53,31,806,1830,2169,452,115,1207,285,588,425,2089,1720,1396,203,178,864,727,362,1798
-0.42583141250889395,0.29436510731780724,-0.7351237916771668,0.087264561932277,-0.15232095828757117,0.027665838086341914,0.4117021682718201,-0.30372981581819986,0.14667069399718627,-0.5179988657470733,-0.21272571549189503,0.3531228099863507,-0.6417070956037559,-1.3406374671292853,-0.002206819462379813,0.05748948699344504,-0.364669859579678,0.3237664369124269,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,0.027665838086341914,-0.12219648225605645,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.47010609080532134,-0.15232095828757117,0.3237664369124269,-0.33417242136584113,0.4409258805823772,0.4409258805823772,0.615366695909301,0.8169980768047461,0.23542606283924014,-0.3952226726312979,1.1017238127490079,-0.09212329847709767,-0.987047828674115,1.6880249517622525,-0.27334151033073334,-0.5488370384270144,0.730826559921213,0.05748948699344504,-0.12219648225605645,-0.6106905307608944,-0.4564966412770062,0.4992431492624739,0.14667069399718627,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,-0.15232095828757117,0.5573891868193322,0.087264561932277,1.3548410508645194,0.47010609080532134,-0.24300698162028928,0.615366695909301,-0.33417242136584113,0.05748948699344504,0.2649184437199032,-0.364669859579678,-0.27334151033073334,0.47010609080532134,0.5573891868193322,0.4992431492624739,-0.3952226726312979,-0.8291051207987041,0.3237664369124269,-0.09212329847709767,0.8169980768047461,0.2058875754695338,0.4992431492624739,0.4992431492624739,0.3531228099863507,0.38243459835151017,-0.09212329847709767,-0.6106905307608944,-0.5797340545401417,0.615366695909301,-0.12219648225605645,-0.8920824087947153,0.17630258634391707,-0.06210093493456228,0.6731783026903564,-0.03212892744333096,-0.3952226726312979,-0.4872189313453426,1.298839486996753,0.3531228099863507,1.7705913566526543,0.4409258805823772,-1.0188392846787804,1.1582216374253231,0.2649184437199032,-0.5488370384270144,-0.182497206611748,1.88024377397462,2.5016288793513897,0.2649184437199032,-0.4564966412770062,-0.7977141188950565,0.5573891868193322,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.5863988415320117,-0.7039230664205183,-0.364669859579678,-0.12219648225605645,0.9882872661563274,1.0734201781652684,0.23542606283924014,0.3237664369124269,0.6731783026903564,-0.42583141250889395
2,448
Negative regulation of cell projection organization
10
21
2.064542
0.038966
Q9NR77,Q86X55,Q8N0X7,O14786,Q00535,P50570,P61586,P08670,Q96G23,Q02790
Processes and pathways
GO Biological process
msigdb_gobp
59,445,373,508,370,469,25,515,93,193
508,1678,1835,515,1005,912,657,2021,1180,1100,469,25,370,193,572,445,373,1289,93,2031,59
0.47010609080532134,-0.364669859579678,-0.4872189313453426,0.47010609080532134,0.11699149062391306,0.17630258634391707,0.3531228099863507,-0.6417070956037559,-0.002206819462379813,0.05748948699344504,0.5283374011848795,2.581598099731636,0.6442930758559092,1.0167021690167521,0.4409258805823772,0.5573891868193322,0.6442930758559092,-0.06210093493456228,1.4942473318432876,-0.6417070956037559,1.825479230161245
2,448
Sh3 domain binding
7
8
2.060887
0.039314
P42566,Q96PU8,P62993,Q16204,P50570,Q9Y5K6,Q07666
Functions
GO Molecular function
msigdb_gomf
416,542,293,210,469,362,532
416,469,293,532,210,637,542,362
0.5863988415320117,0.5283374011848795,0.7595902108481608,0.47010609080532134,0.9598347398148359,0.38243459835151017,0.47010609080532134,0.6731783026903564
2,448
Negative regulation of neuron projection development
8
14
2.055222
0.039858
Q86X55,Q8N0X7,O14786,Q00535,P61586,Q9NR77,Q96G23,Q02790
Processes and pathways
GO Biological process
msigdb_gobp
445,373,508,370,25,59,93,193
508,1678,515,1005,657,25,370,193,445,373,1289,93,2031,59
0.47010609080532134,-0.364669859579678,0.47010609080532134,0.11699149062391306,0.3531228099863507,2.581598099731636,0.6442930758559092,1.0167021690167521,0.5573891868193322,0.6442930758559092,-0.06210093493456228,1.4942473318432876,-0.6417070956037559,1.825479230161245
2,448
Rotamase
6
18
2.051817
0.040187
Q9H2H8,Q13526,Q15257,Q96AY3,Q9Y3C6,Q02790
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
96,175,55,26,195,193
1679,2019,468,2098,1496,914,972,193,1465,232,175,2187,55,1243,26,96,2034,195
-0.364669859579678,-0.6417070956037559,0.5283374011848795,-0.7351237916771668,-0.21272571549189503,0.17630258634391707,0.14667069399718627,1.0167021690167521,-0.182497206611748,0.9028157215260153,1.0734201781652684,-0.8291051207987041,1.8528768241204838,-0.03212892744333096,2.5549681424265085,1.4664334747935266,-0.6417070956037559,1.0167021690167521
2,448
Positive regulation of ion transmembrane transport
10
22
2.051325
0.040235
P50570,P11413,P27695,P30626,P0DP25,Q00535,O14745,P54652,P28161,P35609
Processes and pathways
GO Biological process
msigdb_gobp
469,342,344,413,240,370,207,311,116,434
1677,207,1259,1687,1769,1990,240,342,1005,344,116,413,434,469,311,1141,920,370,485,1377,1122,863
-0.364669859579678,0.9598347398148359,-0.06210093493456228,-0.364669859579678,-0.42583141250889395,-0.6106905307608944,0.8742486728862037,0.6731783026903564,0.11699149062391306,0.6731783026903564,1.3268575727799916,0.5863988415320117,0.5573891868193322,0.5283374011848795,0.730826559921213,0.027665838086341914,0.17630258634391707,0.6442930758559092,0.4992431492624739,-0.12219648225605645,0.05748948699344504,0.23542606283924014
2,448
Calcium-binding protein
7
16
2.048962
0.040466
Q14257,Q9Y376,P31949,P80303,P0DP25,Q02818,Q99584
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
441,170,414,107,240,182,127
1302,240,1137,414,1994,918,1369,107,182,441,1381,1285,1330,127,583,170
-0.09212329847709767,0.8742486728862037,0.027665838086341914,0.5863988415320117,-0.6106905307608944,0.17630258634391707,-0.12219648225605645,1.3827901527630164,1.0450797177342925,0.5573891868193322,-0.12219648225605645,-0.06210093493456228,-0.09212329847709767,1.298839486996753,0.4409258805823772,1.1017238127490079
2,448
RAS pathway related proteins
9
15
2.047257
0.040633
P20339,P62993,Q13177,P0DP25,P60953,Q9UQ13,P61586,P11233,Q06124
Functions
Protein Atlas Protein class
protein_atlas_protein_class
230,293,626,240,595,426,25,517,295
240,517,686,230,1221,1494,1319,1063,595,25,293,786,295,626,426
0.8742486728862037,0.47010609080532134,0.3237664369124269,0.9028157215260153,-0.03212892744333096,-0.21272571549189503,-0.09212329847709767,0.087264561932277,0.4117021682718201,2.581598099731636,0.7595902108481608,0.2649184437199032,0.7595902108481608,0.38243459835151017,0.5863988415320117
2,448
Apoptosis
34
79
2.045988
0.040758
P48556,Q13200,Q15149,P08670,P25789,P09429,Q04917,P25787,P49721,Q9UDY2,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q14974,Q99436,P35998,P51665,P63104,P20618,O00273,O43242,Q9NR28,Q13177,P49354,P40763,P60900,Q07812,Q15008,Q06323,Q92530
Processes and pathways
Reactome Pathways
msigdb_reactome
260,390,665,515,275,653,572,291,167,46,581,49,51,588,54,724,550,705,69,691,77,698,220,226,227,376,626,242,241,484,485,488,531,397
550,946,226,1347,1766,730,227,2036,1872,1574,2203,1989,515,653,1688,1624,1176,2063,1052,220,1004,1310,291,1268,275,1311,1221,1727,54,49,51,1494,875,1455,1407,1365,691,241,1650,260,1013,242,1728,167,2286,77,1320,1102,484,969,783,697,1503,1586,1463,698,2361,572,531,1146,1235,485,626,390,1507,842,1736,705,488,665,397,69,581,1161,376,46,941,588,724
0.4409258805823772,0.14667069399718627,0.9028157215260153,-0.12219648225605645,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.6727843897556249,-0.5179988657470733,-0.27334151033073334,-0.8605609719945663,-0.6106905307608944,0.47010609080532134,0.3531228099863507,-0.364669859579678,-0.30372981581819986,-0.002206819462379813,-0.7039230664205183,0.087264561932277,0.9313443171057458,0.11699149062391306,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.09212329847709767,-0.03212892744333096,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.21272571549189503,0.2058875754695338,-0.182497206611748,-0.15232095828757117,-0.12219648225605645,0.3237664369124269,0.8742486728862037,-0.33417242136584113,0.8169980768047461,0.11699149062391306,0.8742486728862037,-0.3952226726312979,1.1017238127490079,-0.987047828674115,1.6880249517622525,-0.09212329847709767,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.2649184437199032,0.3237664369124269,-0.21272571549189503,-0.27334151033073334,-0.182497206611748,0.3237664369124269,-1.2757154640498929,0.4409258805823772,0.47010609080532134,0.027665838086341914,-0.03212892744333096,0.4992431492624739,0.38243459835151017,0.615366695909301,-0.21272571549189503,0.23542606283924014,-0.3952226726312979,0.3237664369124269,0.4992431492624739,0.3531228099863507,0.615366695909301,1.7705913566526543,0.4409258805823772,0.027665838086341914,0.6442930758559092,1.9621626060274844,0.17630258634391707,0.4409258805823772,0.3237664369124269
2,448
Regulation of protein modification by small protein conjugation or removal
28
68
2.043857
0.040968
Q9UBT2,Q16763,P48506,P19474,P68036,Q9BUN8,O75340,O94874,Q13155,Q6DKJ4,Q13526,Q96MG7,Q5VTR2,Q6PD62,P61927,P31689,P63208,Q9UBV8,Q9NW82,O60678,O75592,Q7Z6Z7,Q96FW1,Q04323,Q00535,P46777,Q9NVI1,Q96J02
Processes and pathways
GO Biological process
msigdb_gobp
402,264,385,18,661,159,160,648,573,575,175,718,443,58,192,558,439,604,216,218,219,634,638,111,370,369,400,126
1399,1129,768,1486,1571,218,950,160,219,1872,648,869,1002,1172,1097,1306,18,774,1992,558,1407,1011,369,385,1585,1368,1541,782,192,1371,1628,1415,439,661,370,111,573,1659,2025,175,1702,1815,707,264,443,575,58,634,933,638,126,1198,718,2303,159,2010,2011,937,400,1520,216,1830,2169,989,402,604,1122,1720
-0.15232095828757117,0.027665838086341914,0.2649184437199032,-0.21272571549189503,-0.27334151033073334,0.9313443171057458,0.14667069399718627,1.1299908805711318,0.9313443171057458,-0.5179988657470733,0.3531228099863507,0.2058875754695338,0.11699149062391306,-0.002206819462379813,0.05748948699344504,-0.09212329847709767,3.7035378773687953,0.2649184437199032,-0.6106905307608944,0.4409258805823772,-0.15232095828757117,0.11699149062391306,0.6442930758559092,0.615366695909301,-0.27334151033073334,-0.12219648225605645,-0.24300698162028928,0.2649184437199032,1.0167021690167521,-0.12219648225605645,-0.30372981581819986,-0.15232095828757117,0.5573891868193322,0.3531228099863507,0.6442930758559092,1.3548410508645194,0.4409258805823772,-0.33417242136584113,-0.6417070956037559,1.0734201781652684,-0.364669859579678,-0.4564966412770062,0.3237664369124269,0.8169980768047461,0.5573891868193322,0.4409258805823772,1.825479230161245,0.38243459835151017,0.17630258634391707,0.38243459835151017,1.298839486996753,-0.002206819462379813,0.3237664369124269,-1.0188392846787804,1.1582216374253231,-0.6106905307608944,-0.6106905307608944,0.17630258634391707,0.615366695909301,-0.21272571549189503,0.9598347398148359,-0.4564966412770062,-0.7977141188950565,0.14667069399718627,0.615366695909301,0.4117021682718201,0.05748948699344504,-0.364669859579678
2,448
Peptidyl proline modification
9
29
2.038812
0.041469
Q9H2H8,Q13451,Q13526,Q15257,O75718,Q96AY3,Q9Y3C6,O15460,Q02790
Processes and pathways
GO Biological process
msigdb_gobp
96,232,175,55,306,26,195,29,193
1041,29,1679,306,1532,553,2019,468,2098,1496,914,1729,972,193,1465,1814,232,175,2187,55,795,330,1243,26,934,2282,96,2034,195
0.087264561932277,2.5016288793513897,-0.364669859579678,0.730826559921213,-0.24300698162028928,0.4409258805823772,-0.6417070956037559,0.5283374011848795,-0.7351237916771668,-0.21272571549189503,0.17630258634391707,-0.3952226726312979,0.14667069399718627,1.0167021690167521,-0.182497206611748,-0.4564966412770062,0.9028157215260153,1.0734201781652684,-0.8291051207987041,1.8528768241204838,0.2649184437199032,0.7020226932379363,-0.03212892744333096,2.5549681424265085,0.17630258634391707,-0.9553250615605502,1.4664334747935266,-0.6417070956037559,1.0167021690167521
2,448
Nucleoside triphosphatase regulator activity
23
56
2.037641
0.041586
Q8N6T3,O14786,Q9Y2L1,O60343,P29692,Q02818,Q8TC07,P55010,P18085,P43487,Q9BTW9,P52565,Q9H6Z4,Q15042,Q9H3U1,P24534,Q9P258,O75592,Q9NWX6,P80303,Q9UI10,Q9NR50,Q15436
Functions
GO Molecular function
msigdb_gomf
144,508,427,288,292,182,186,62,433,435,476,326,357,209,355,466,360,219,102,107,379,245,123
606,1347,508,1951,288,219,1835,511,433,2114,466,292,657,435,1694,964,1695,1729,1100,326,62,2361,107,182,701,1417,841,1150,2212,706,209,1078,123,979,633,1472,932,144,186,797,983,2278,1432,476,1558,355,357,1204,245,102,2243,360,1121,379,427,1609
0.38243459835151017,-0.12219648225605645,0.47010609080532134,-0.5797340545401417,0.7595902108481608,0.9313443171057458,-0.4872189313453426,0.47010609080532134,0.5573891868193322,-0.7663872448501347,0.5283374011848795,0.7595902108481608,0.3531228099863507,0.5573891868193322,-0.364669859579678,0.14667069399718627,-0.364669859579678,-0.3952226726312979,0.05748948699344504,0.7020226932379363,1.798050804303417,-1.2757154640498929,1.3827901527630164,1.0450797177342925,0.3237664369124269,-0.15232095828757117,0.23542606283924014,0.027665838086341914,-0.8605609719945663,0.3237664369124269,0.9598347398148359,0.087264561932277,1.298839486996753,0.14667069399718627,0.38243459835151017,-0.182497206611748,0.17630258634391707,1.2145752253051996,1.0450797177342925,0.2649184437199032,0.14667069399718627,-0.9553250615605502,-0.15232095828757117,0.5283374011848795,-0.24300698162028928,0.6731783026903564,0.6731783026903564,-0.002206819462379813,0.8742486728862037,1.4385861401124023,-0.8920824087947153,0.6731783026903564,0.05748948699344504,0.6442930758559092,0.5863988415320117,-0.27334151033073334
2,448
Separation of sister chromatids
40
87
2.027156
0.042646
Q92530,Q16763,P48556,Q9Y6G9,Q9UJX4,Q13200,O43264,O43683,P25789,P30260,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,O43237,Q99436,P35998,P51665,Q9Y266,Q9BUF5,P68371,P62191,Q9P258,Q7Z460,P20618,Q13409,Q8N3U4,O43242,Q15691,Q8NFH4,Q9UJX2,P60900,Q15008,Q06323,P30153
Processes and pathways
Reactome Pathways
msigdb_reactome
397,264,260,286,285,390,644,645,275,519,291,167,581,49,51,588,54,724,550,551,69,691,77,480,354,699,697,360,752,220,231,636,227,112,114,115,484,488,531,618
1483,550,946,1766,730,1401,551,227,644,645,768,866,1571,1872,1052,220,1310,291,1268,275,1727,54,49,51,618,961,519,691,1650,1694,260,1728,167,1729,77,1655,1585,1102,1231,484,969,697,1503,1463,2361,699,531,1506,390,231,2211,1149,881,1783,843,1886,488,112,264,847,1110,2127,752,636,114,754,1634,397,1938,69,581,1713,354,2351,1900,1940,1437,1343,360,115,1207,285,588,724,1562,480,286
-0.21272571549189503,0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,-0.15232095828757117,0.4409258805823772,0.9028157215260153,0.3531228099863507,0.3531228099863507,0.2649184437199032,0.2058875754695338,-0.27334151033073334,-0.5179988657470733,0.087264561932277,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,0.38243459835151017,0.14667069399718627,0.47010609080532134,0.3237664369124269,-0.33417242136584113,-0.364669859579678,0.8169980768047461,-0.3952226726312979,1.1017238127490079,-0.3952226726312979,1.6880249517622525,-0.33417242136584113,-0.27334151033073334,0.05748948699344504,-0.03212892744333096,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,-1.2757154640498929,0.3237664369124269,0.47010609080532134,-0.21272571549189503,0.615366695909301,0.9028157215260153,-0.8605609719945663,0.027665838086341914,0.2058875754695338,-0.42583141250889395,0.23542606283924014,-0.5179988657470733,0.4992431492624739,1.3548410508645194,0.8169980768047461,0.23542606283924014,0.05748948699344504,-0.7663872448501347,0.29436510731780724,0.38243459835151017,1.3548410508645194,0.29436510731780724,-0.30372981581819986,0.615366695909301,-0.5488370384270144,1.7705913566526543,0.4409258805823772,-0.364669859579678,0.6731783026903564,-1.211071046856623,-0.5179988657470733,-0.5488370384270144,-0.15232095828757117,-0.09212329847709767,0.6731783026903564,1.3548410508645194,-0.002206819462379813,0.7883139498979853,0.4409258805823772,0.3237664369124269,-0.24300698162028928,0.5283374011848795,0.7883139498979853
2,448
Actin cytoskeleton
34
106
2.013591
0.044052
Q9NYL9,Q9C0C2,Q9UQB8,Q14847,Q14019,P04083,O15143,O15144,Q92547,P35579,O75340,Q8WX93,Q99439,Q14247,Q01518,P35241,Q96HC4,Q9NQW6,Q9UJW0,Q13325,O00151,P35609,P15311,Q9Y281,P41440,P61978,Q05682,O14745,Q9Y5K6,P27695,P20339,Q15942,P17655,Q92747
Localization
GO Cellular component
msigdb_gocc
401,545,134,138,137,15,380,509,157,523,160,162,39,574,294,415,580,320,587,183,428,434,432,204,71,438,440,207,362,344,230,108,367,398
428,1611,207,380,509,1612,1614,1259,1569,1260,160,952,681,1681,1767,1724,15,1305,1989,1915,684,1356,1580,432,367,614,1453,230,1005,1267,344,616,913,415,523,593,434,1365,71,2041,964,1627,1180,916,570,918,1997,1880,836,438,2361,879,294,440,1235,1965,1376,1147,2002,2044,183,1071,841,842,137,574,1631,2188,138,1422,749,108,977,1152,1027,1191,1550,1112,716,162,157,398,2081,580,39,720,985,2326,545,938,320,760,401,2340,763,587,1440,1297,1642,2264,134,204,808,362,1346,728
0.5573891868193322,-0.30372981581819986,0.9598347398148359,0.615366695909301,0.47010609080532134,-0.30372981581819986,-0.30372981581819986,-0.06210093493456228,-0.27334151033073334,-0.06210093493456228,1.1299908805711318,0.14667069399718627,0.3237664369124269,-0.364669859579678,-0.42583141250889395,-0.3952226726312979,4.161025061636598,-0.09212329847709767,-0.6106905307608944,-0.5488370384270144,0.3237664369124269,-0.12219648225605645,-0.27334151033073334,0.5573891868193322,0.6442930758559092,0.38243459835151017,-0.182497206611748,0.9028157215260153,0.11699149062391306,-0.06210093493456228,0.6731783026903564,0.38243459835151017,0.17630258634391707,0.5863988415320117,0.47010609080532134,0.4117021682718201,0.5573891868193322,-0.12219648225605645,1.7431006951795138,-0.6727843897556249,0.14667069399718627,-0.30372981581819986,-0.002206819462379813,0.17630258634391707,0.4409258805823772,0.17630258634391707,-0.6106905307608944,-0.5179988657470733,0.23542606283924014,0.5573891868193322,-1.2757154640498929,0.2058875754695338,0.7595902108481608,0.5573891868193322,-0.03212892744333096,-0.5797340545401417,-0.12219648225605645,0.027665838086341914,-0.6106905307608944,-0.6727843897556249,1.0450797177342925,0.087264561932277,0.23542606283924014,0.23542606283924014,1.2426985519939489,0.4409258805823772,-0.30372981581819986,-0.8291051207987041,1.2426985519939489,-0.15232095828757117,0.29436510731780724,1.3827901527630164,0.14667069399718627,0.027665838086341914,0.11699149062391306,-0.002206819462379813,-0.24300698162028928,0.05748948699344504,0.3237664369124269,1.1299908805711318,1.1582216374253231,0.615366695909301,-0.7039230664205183,0.4409258805823772,2.1251973259084997,0.3237664369124269,0.14667069399718627,-1.114634054017247,0.47010609080532134,0.17630258634391707,0.730826559921213,0.29436510731780724,0.615366695909301,-1.1467083845303592,0.29436510731780724,0.4409258805823772,-0.15232095828757117,-0.06210093493456228,-0.30372981581819986,-0.9236701828387313,1.2707865591544374,0.9882872661563274,0.2649184437199032,0.6731783026903564,-0.09212329847709767,0.3237664369124269
2,448
nucleoplasm
98
308
2.011985
0.044222
Q8WXF1,Q9UPN9,Q7L2H7,O95373,O95861,P61586,O00267,P50995,Q13363,P31948,P14174,P30260,Q9H4L7,Q99439,Q99460,P28072,P28074,Q9UL46,P28070,P55060,P30876,O00231,O43237,Q9H1E3,Q99436,P31689,P52701,P38159,P46379,P51665,Q96SY0,P78362,P60953,Q9H2J4,Q16630,P17096,Q13685,Q15691,Q9UJX2,Q01844,Q9NVZ3,O43633,Q7Z4Q2,P98179,Q16637,O75340,Q96EY4,Q9NZB2,Q9Y3C8,P49721,Q9H814,P25685,P20618,Q13451,O43242,P0DP25,O60869,O43592,Q96AX1,O60684,Q8TEX9,Q96T37,Q92973,P25789,P62993,P25787,P61081,O15212,Q99816,P05204,Q9NYV4,O75937,Q13148,O15355,Q9NTZ6,Q00535,P11802,Q92530,Q5BKZ1,P00338,Q13200,Q12824,Q8WXX5,Q66PJ3,P30626,Q96EK5,O95456,Q9UBB4,Q08945,Q96S59,Q9UN37,P04406,Q5VYK3,P60900,Q13263,Q15008,Q15418,Q06323
Localization
OpenCell Localization
opencell_localization
540,546,11,511,513,25,507,524,32,521,35,519,38,39,581,49,51,588,54,569,557,550,551,66,69,558,566,559,562,77,603,597,595,101,628,97,627,112,115,119,129,130,140,149,156,160,163,165,171,167,176,208,220,232,227,240,239,238,253,250,265,267,266,275,293,291,314,304,332,324,359,341,346,338,378,370,366,397,393,382,390,417,421,419,413,448,430,479,470,498,505,481,492,484,487,488,489,531
1483,550,946,507,606,1348,1870,1949,1043,1128,1401,1612,304,338,2171,811,1213,1613,904,551,227,238,130,645,866,867,250,239,868,1987,950,1351,160,2375,1872,341,1216,511,1619,430,732,513,1684,382,1304,481,324,817,683,1770,1620,1989,1002,1915,1172,1049,1097,240,1991,1050,2112,2268,366,1689,822,1098,35,823,1579,2178,97,1691,1219,1052,1266,2323,1308,1582,220,827,1358,828,1803,959,208,1310,291,1268,275,689,1054,1311,1221,1727,54,49,51,1179,1494,519,413,557,657,558,1055,1455,521,1626,1056,691,1010,1583,1224,559,1316,1804,1537,1225,1774,2099,1650,1775,562,2041,1180,1651,833,2309,1013,1059,2371,1728,167,1318,1100,2254,1181,1539,524,1807,77,1227,1182,1320,566,967,1585,917,1962,622,2069,1015,1102,569,1368,1540,1731,484,595,314,745,969,25,783,1503,1586,1463,2273,1017,293,698,2361,1698,699,1145,597,785,1416,921,149,370,2152,2153,119,531,1965,470,922,417,1928,346,1148,626,390,487,924,1070,32,232,2025,747,627,788,1280,880,790,1783,705,1592,1022,488,2074,748,1281,489,666,2105,112,1470,1324,2311,1382,628,156,978,711,393,492,419,11,140,884,1285,2312,636,1595,265,1555,716,540,421,397,755,1289,2235,1597,266,1556,1290,1291,253,448,163,2194,1973,1668,674,1117,798,498,603,267,69,39,581,1200,1713,332,1335,1899,1791,1337,2368,937,2012,66,1202,101,38,1559,176,803,1757,378,129,359,165,1830,479,989,1256,1675,1344,115,588,2089,505,723,724,1982,546,1864,1906,680,171,1643,2380,1722
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2,448
Response to peptide hormone
21
69
2.004108
0.045059
Q9UQB8,P48506,P04083,P43490,Q06124,O60343,P07741,P62993,P56537,Q9Y5X3,P35609,Q9H1E3,Q13247,P09960,P35613,Q96A49,P27695,Q9UI10,Q9NR50,P40763,P11802
Processes and pathways
GO Biological process
msigdb_gobp
134,385,15,17,295,288,410,293,313,321,434,66,73,197,76,353,344,379,245,241,366
1611,2035,994,1129,288,646,950,15,734,410,871,2224,1049,197,366,1579,1838,2039,1177,2040,1625,344,434,76,241,2117,831,1270,1408,17,1694,385,1695,1318,1103,313,1963,744,783,293,1416,295,2333,2000,1417,746,73,1507,1150,2311,2190,2106,1855,599,1028,1857,1115,853,2235,353,2318,1792,66,938,245,379,134,480,321
-0.30372981581819986,-0.6727843897556249,0.11699149062391306,0.027665838086341914,0.7595902108481608,0.3531228099863507,0.14667069399718627,4.161025061636598,0.29436510731780724,0.5863988415320117,0.2058875754695338,-0.8920824087947153,0.087264561932277,0.9882872661563274,0.6442930758559092,-0.27334151033073334,-0.4872189313453426,-0.6727843897556249,-0.002206819462379813,-0.6727843897556249,-0.30372981581819986,0.6731783026903564,0.5573891868193322,1.6880249517622525,0.8742486728862037,-0.7663872448501347,0.23542606283924014,-0.06210093493456228,-0.15232095828757117,3.856772038666039,-0.364669859579678,0.615366695909301,-0.364669859579678,-0.09212329847709767,0.05748948699344504,0.730826559921213,-0.5797340545401417,0.29436510731780724,0.2649184437199032,0.7595902108481608,-0.15232095828757117,0.7595902108481608,-1.1467083845303592,-0.6106905307608944,-0.15232095828757117,0.29436510731780724,1.7431006951795138,-0.21272571549189503,0.027665838086341914,-1.0507002473854663,-0.8291051207987041,-0.7351237916771668,-0.4872189313453426,0.4117021682718201,0.11699149062391306,-0.4872189313453426,0.05748948699344504,0.23542606283924014,-0.8920824087947153,0.6731783026903564,-1.0826315524646415,-0.42583141250889395,1.798050804303417,0.17630258634391707,0.8742486728862037,0.6442930758559092,1.2707865591544374,0.5283374011848795,0.730826559921213
2,448
Clubbing
6
14
2.002376
0.045244
Q9H4L7,Q9BXW9,Q86TI2,Q96AX1,P09884,Q9NVI1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
38,244,212,253,464,400
952,464,1624,1307,467,1011,778,1103,212,670,253,244,38,400
0.14667069399718627,0.5283374011848795,-0.30372981581819986,-0.09212329847709767,0.5283374011848795,0.11699149062391306,0.2649184437199032,0.05748948699344504,0.9598347398148359,0.3531228099863507,0.8456428872388043,0.8742486728862037,2.1793094146987886,0.615366695909301
2,448
Intracellular signaling by second messengers
32
72
2.001323
0.045358
Q92530,P48556,Q13200,P25789,Q06124,P62993,P10644,P25787,P49721,Q99460,P28072,P28074,Q9UL46,P28070,Q9UNM6,O00231,Q99436,P17612,P35998,P51665,P62191,O95983,P20618,Q6IAA8,Q96B36,O43242,Q13547,Q8WXI9,P60900,Q15008,Q06323,P30153
Processes and pathways
Reactome Pathways
msigdb_reactome
397,260,390,275,295,293,654,291,167,581,49,51,588,54,724,550,69,686,691,77,697,462,220,633,100,227,747,375,484,488,531,618
550,946,1766,730,227,1486,1872,1303,462,2203,654,1623,2038,686,1052,1582,220,1310,291,1268,275,1221,1727,54,49,51,1494,618,961,691,1408,1650,260,1728,167,1318,77,1182,1102,484,969,697,1503,1463,293,1698,1587,295,531,390,1659,747,843,1076,488,2157,1968,633,1029,375,397,1289,1290,100,69,581,1203,2168,2108,588,1720,724
0.4409258805823772,0.14667069399718627,-0.42583141250889395,0.29436510731780724,0.9028157215260153,-0.21272571549189503,-0.5179988657470733,-0.09212329847709767,0.5283374011848795,-0.8605609719945663,0.3531228099863507,-0.30372981581819986,-0.6727843897556249,0.3237664369124269,0.087264561932277,-0.27334151033073334,0.9313443171057458,-0.09212329847709767,0.7595902108481608,-0.06210093493456228,0.7883139498979853,-0.03212892744333096,-0.3952226726312979,1.8528768241204838,1.9075802654498024,1.88024377397462,-0.21272571549189503,0.38243459835151017,0.14667069399718627,0.3237664369124269,-0.15232095828757117,-0.33417242136584113,0.8169980768047461,-0.3952226726312979,1.1017238127490079,-0.09212329847709767,1.6880249517622525,-0.002206819462379813,0.05748948699344504,0.4992431492624739,0.14667069399718627,0.3237664369124269,-0.21272571549189503,-0.182497206611748,0.7595902108481608,-0.364669859579678,-0.27334151033073334,0.7595902108481608,0.47010609080532134,0.615366695909301,-0.33417242136584113,0.29436510731780724,0.23542606283924014,0.087264561932277,0.4992431492624739,-0.7977141188950565,-0.5797340545401417,0.38243459835151017,0.11699149062391306,0.6442930758559092,0.615366695909301,-0.06210093493456228,-0.06210093493456228,1.4385861401124023,1.7705913566526543,0.4409258805823772,-0.002206819462379813,-0.7977141188950565,-0.7351237916771668,0.4409258805823772,-0.364669859579678,0.3237664369124269
2,448
Regulation of actin cytoskeleton reorganization
6
9
1.997203
0.045803
Q9Y624,Q9UQB8,P52565,O14786,Q00535,Q9Y5K6
Processes and pathways
GO Biological process
msigdb_gobp
405,134,326,508,370,362
508,326,595,370,1235,841,134,362,405
0.47010609080532134,0.7020226932379363,0.4117021682718201,0.6442930758559092,-0.03212892744333096,0.23542606283924014,1.2707865591544374,0.6731783026903564,0.615366695909301
2,448
Phosphatase regulator activity
10
17
1.988184
0.046791
Q5H9R7,O43768,Q9BTT0,P17931,Q86XL3,P0DP25,Q15257,Q9UQ13,Q01105,P30153
Functions
GO Molecular function
msigdb_gomf
629,407,582,368,600,240,55,426,154,618
407,240,368,1405,618,961,660,1104,154,1812,843,55,629,600,1390,582,426
0.5863988415320117,0.8742486728862037,0.6442930758559092,-0.15232095828757117,0.38243459835151017,0.14667069399718627,0.3531228099863507,0.05748948699344504,1.1582216374253231,-0.4564966412770062,0.23542606283924014,1.8528768241204838,0.38243459835151017,0.4117021682718201,-0.12219648225605645,0.4409258805823772,0.5863988415320117
2,448
Abnormality of the female genitalia
20
104
1.986586
0.046968
P48735,O75874,P43246,Q06124,Q13363,Q8WX93,Q15645,Q15392,Q9BW83,Q9UPY3,Q9UNW1,P22570,Q15042,Q92766,Q9UI10,Q03252,Q9NR50,Q9BXW9,Q01844,O75312
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
3,7,276,295,32,162,298,43,45,60,80,82,209,351,379,243,245,244,119,363
1040,1041,2091,1871,904,645,768,866,1571,1350,1987,2357,363,2349,1723,7,1875,1684,1685,1574,2203,1988,2342,654,1956,2039,1958,1053,82,960,618,1648,1407,1498,1315,1366,1011,276,3,1013,1695,1653,1654,2148,1227,566,1229,2069,1231,1541,2361,878,1185,119,243,295,1544,485,598,389,1417,32,1418,1150,1783,2377,209,844,43,666,298,1324,1027,1237,1933,1550,575,1383,750,2312,1115,162,351,1333,1387,2302,1669,45,244,1940,642,1393,245,400,2086,1480,807,379,2138,80,60,1562,1867,1524
0.087264561932277,0.087264561932277,-0.7351237916771668,-0.5179988657470733,0.17630258634391707,0.3531228099863507,0.2649184437199032,0.2058875754695338,-0.27334151033073334,-0.12219648225605645,-0.6106905307608944,-1.2757154640498929,0.6442930758559092,-1.211071046856623,-0.3952226726312979,5.594030281929976,-0.5179988657470733,-0.364669859579678,-0.364669859579678,-0.27334151033073334,-0.8605609719945663,-0.6106905307608944,-1.1788542301541802,0.3531228099863507,-0.5797340545401417,-0.6727843897556249,-0.5797340545401417,0.087264561932277,1.660439474765213,0.14667069399718627,0.38243459835151017,-0.33417242136584113,-0.15232095828757117,-0.21272571549189503,-0.09212329847709767,-0.12219648225605645,0.11699149062391306,0.7883139498979853,6.432398994236586,0.11699149062391306,-0.364669859579678,-0.33417242136584113,-0.33417242136584113,-0.7977141188950565,-0.03212892744333096,0.4409258805823772,-0.03212892744333096,-0.7039230664205183,-0.03212892744333096,-0.24300698162028928,-1.2757154640498929,0.2058875754695338,-0.002206819462379813,1.3268575727799916,0.8742486728862037,0.7595902108481608,-0.24300698162028928,0.4992431492624739,0.4117021682718201,0.615366695909301,-0.15232095828757117,2.474919285820168,-0.15232095828757117,0.027665838086341914,-0.42583141250889395,-1.4058330257519098,0.9598347398148359,0.23542606283924014,1.9621626060274844,0.3531228099863507,0.7595902108481608,-0.09212329847709767,0.11699149062391306,-0.03212892744333096,-0.5488370384270144,-0.24300698162028928,0.4409258805823772,-0.12219648225605645,0.29436510731780724,-1.0507002473854663,0.05748948699344504,1.1299908805711318,0.6731783026903564,-0.09212329847709767,-0.12219648225605645,-1.0188392846787804,-0.33417242136584113,1.9621626060274844,0.8742486728862037,-0.5488370384270144,0.38243459835151017,-0.12219648225605645,0.8742486728862037,0.615366695909301,-0.7039230664205183,-0.182497206611748,0.2649184437199032,0.6442930758559092,-0.7663872448501347,1.6880249517622525,1.825479230161245,-0.24300698162028928,-0.4872189313453426,-0.21272571549189503
2,448
Regulation of cell differentiation
41
169
1.985291
0.047112
Q8WUJ1,Q9UQB8,Q96T37,Q9Y624,Q8N4Q0,P04179,P04083,Q08J23,Q99873,P61586,Q04637,Q06124,O60271,P26196,P56537,Q8WX92,Q6PD62,Q9UPY3,O15047,Q15014,Q13247,Q92688,Q96A49,Q9C0B1,Q9H3U1,Q9NYV4,Q9P258,Q92766,Q96G23,Q99829,P11413,Q9Y5A9,P27695,Q9BXW9,Q8N0X7,P40763,P17931,Q00535,O14744,O15347,Q96J02
Processes and pathways
GO Biological process
msigdb_gobp
1,134,267,405,12,142,15,389,283,25,278,295,408,412,313,50,58,60,61,63,73,213,353,84,355,359,360,351,93,233,342,236,344,244,373,241,368,370,237,248,126
1168,1042,1400,237,508,2091,61,509,248,2173,1259,1445,408,1486,1260,1351,1952,1835,1874,648,1573,1131,1684,733,1170,15,142,2203,2430,1769,734,683,552,1532,1172,653,1049,1097,342,685,1174,2039,686,1219,368,614,1405,1005,773,412,1099,1493,344,1137,1494,618,657,1139,913,1407,1365,2207,619,241,1270,1408,1776,1318,469,1925,1227,742,313,1369,595,25,783,2332,528,529,1416,370,2152,786,278,572,295,2354,2333,1146,389,923,73,1507,747,1378,704,789,1631,790,1592,63,2157,489,793,709,2311,667,1152,750,58,1114,1028,752,445,373,12,1551,1,50,213,351,1289,577,1667,2418,983,353,2081,93,126,1198,1432,2134,267,1669,2318,233,283,2405,1337,1252,244,861,84,802,1339,2327,892,355,2356,2031,1905,359,2033,360,2108,941,1561,1297,2089,2264,60,1167,134,725,236,405,1525
-0.002206819462379813,0.087264561932277,-0.15232095828757117,0.8742486728862037,0.47010609080532134,-0.7351237916771668,1.798050804303417,0.47010609080532134,0.8456428872388043,-0.8291051207987041,-0.06210093493456228,-0.182497206611748,0.5863988415320117,-0.21272571549189503,-0.06210093493456228,-0.12219648225605645,-0.5797340545401417,-0.4872189313453426,-0.5179988657470733,0.3531228099863507,-0.27334151033073334,0.027665838086341914,-0.364669859579678,0.29436510731780724,-0.002206819462379813,4.161025061636598,1.2145752253051996,-0.8605609719945663,-3.0085610162180214,-0.42583141250889395,0.29436510731780724,0.3237664369124269,0.4409258805823772,-0.24300698162028928,-0.002206819462379813,0.3531228099863507,0.087264561932277,0.05748948699344504,0.6731783026903564,0.3237664369124269,-0.002206819462379813,-0.6727843897556249,0.3237664369124269,-0.03212892744333096,0.6442930758559092,0.38243459835151017,-0.15232095828757117,0.11699149062391306,0.2649184437199032,0.5863988415320117,0.05748948699344504,-0.21272571549189503,0.6731783026903564,0.027665838086341914,-0.21272571549189503,0.38243459835151017,0.3531228099863507,0.027665838086341914,0.17630258634391707,-0.15232095828757117,-0.12219648225605645,-0.8605609719945663,0.38243459835151017,0.8742486728862037,-0.06210093493456228,-0.15232095828757117,-0.42583141250889395,-0.09212329847709767,0.5283374011848795,-0.5488370384270144,-0.03212892744333096,0.29436510731780724,0.730826559921213,-0.12219648225605645,0.4117021682718201,2.581598099731636,0.2649184437199032,-1.1467083845303592,0.47010609080532134,0.47010609080532134,-0.15232095828757117,0.6442930758559092,-0.7977141188950565,0.2649184437199032,0.7883139498979853,0.4409258805823772,0.7595902108481608,-1.243358299991923,-1.1467083845303592,0.027665838086341914,0.615366695909301,0.17630258634391707,1.7431006951795138,-0.21272571549189503,0.29436510731780724,-0.12219648225605645,0.3237664369124269,0.2649184437199032,-0.30372981581819986,0.2649184437199032,-0.27334151033073334,1.798050804303417,-0.7977141188950565,0.4992431492624739,0.2649184437199032,0.3237664369124269,-1.0507002473854663,0.3531228099863507,0.027665838086341914,0.29436510731780724,1.825479230161245,0.05748948699344504,0.11699149062391306,0.29436510731780724,0.5573891868193322,0.6442930758559092,4.437434635650035,-0.24300698162028928,8.218958800035029,1.9075802654498024,0.9598347398148359,0.6731783026903564,-0.06210093493456228,0.4409258805823772,-0.33417242136584113,-2.3797319420179317,0.14667069399718627,0.6731783026903564,-0.7039230664205183,1.4942473318432876,1.298839486996753,-0.002206819462379813,-0.15232095828757117,-0.7663872448501347,0.8169980768047461,-0.33417242136584113,-1.0826315524646415,0.9028157215260153,0.7883139498979853,-1.7024966142654252,-0.09212329847709767,-0.03212892744333096,0.8742486728862037,0.23542606283924014,1.632821993766163,0.2649184437199032,-0.09212329847709767,-1.114634054017247,0.2058875754695338,0.6731783026903564,-1.243358299991923,-0.6417070956037559,-0.5179988657470733,0.6731783026903564,-0.6417070956037559,0.6731783026903564,-0.7351237916771668,0.17630258634391707,-0.24300698162028928,-0.06210093493456228,-0.7039230664205183,-0.9236701828387313,1.825479230161245,0.027665838086341914,1.2707865591544374,0.3237664369124269,0.9028157215260153,0.615366695909301,-0.21272571549189503
2,448
Viral gene expression
9
32
1.984871
0.047159
Q9H1E3,P61009,Q13148,P55884,P56537,P19474,Q99873,Q12824,O14646
Processes and pathways
GO Biological process
msigdb_gobp
66,131,346,327,313,18,283,417,303
1484,303,996,1047,647,1488,817,2038,1052,18,1493,1361,833,1318,1807,327,313,131,1965,417,346,747,1378,1188,974,1738,1739,711,1433,283,66,453
-0.21272571549189503,0.730826559921213,0.11699149062391306,0.087264561932277,0.3531228099863507,-0.21272571549189503,0.23542606283924014,-0.6727843897556249,0.087264561932277,3.7035378773687953,-0.21272571549189503,-0.12219648225605645,0.23542606283924014,-0.09212329847709767,-0.4564966412770062,0.7020226932379363,0.730826559921213,1.2707865591544374,-0.5797340545401417,0.5863988415320117,0.6731783026903564,0.29436510731780724,-0.12219648225605645,-0.002206819462379813,0.14667069399718627,-0.3952226726312979,-0.3952226726312979,0.3237664369124269,-0.15232095828757117,0.7883139498979853,1.798050804303417,0.5573891868193322
2,448
Abnormality of the ovary
9
48
1.977781
0.047953
Q8WX93,P48735,O75874,Q9BW83,Q03252,Q9NR50,Q01844,Q9UPY3,P43246
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
162,3,7,45,243,245,119,60,276
1041,2357,363,2349,1723,7,1684,1574,2203,654,2039,1958,1407,1498,1011,276,3,1013,1695,1653,1654,2148,566,2069,1231,878,1185,119,243,295,1544,1417,1150,2377,844,1027,1933,2312,1115,162,1333,45,1940,245,379,2138,60,1867
0.087264561932277,-1.2757154640498929,0.6442930758559092,-1.211071046856623,-0.3952226726312979,5.594030281929976,-0.364669859579678,-0.27334151033073334,-0.8605609719945663,0.3531228099863507,-0.6727843897556249,-0.5797340545401417,-0.15232095828757117,-0.21272571549189503,0.11699149062391306,0.7883139498979853,6.432398994236586,0.11699149062391306,-0.364669859579678,-0.33417242136584113,-0.33417242136584113,-0.7977141188950565,0.4409258805823772,-0.7039230664205183,-0.03212892744333096,0.2058875754695338,-0.002206819462379813,1.3268575727799916,0.8742486728862037,0.7595902108481608,-0.24300698162028928,-0.15232095828757117,0.027665838086341914,-1.4058330257519098,0.23542606283924014,0.11699149062391306,-0.5488370384270144,-1.0507002473854663,0.05748948699344504,1.1299908805711318,-0.09212329847709767,1.9621626060274844,-0.5488370384270144,0.8742486728862037,0.6442930758559092,-0.7663872448501347,1.825479230161245,-0.4872189313453426
2,448
Adherens junction
15
37
1.97714
0.048026
P35579,P15311,Q9NYL9,Q9C0C2,Q9UQB8,P41440,P31949,P35241,Q9BTW9,Q15942,P78344,P04083,Q9UDY2,Q9Y490,O00151
Localization
GO Cellular component
msigdb_gocc
523,432,401,545,134,71,414,415,476,108,529,15,46,361,428
428,1210,1403,1681,15,1771,1580,432,614,1453,689,414,913,1407,415,523,1365,71,1063,744,2043,529,1235,702,2072,1631,749,108,2081,580,2303,476,545,401,46,134,361
0.5573891868193322,-0.03212892744333096,-0.15232095828757117,-0.364669859579678,4.161025061636598,-0.42583141250889395,-0.27334151033073334,0.5573891868193322,0.38243459835151017,-0.182497206611748,0.3237664369124269,0.5863988415320117,0.17630258634391707,-0.15232095828757117,0.5863988415320117,0.47010609080532134,-0.12219648225605645,1.7431006951795138,0.087264561932277,0.29436510731780724,-0.6727843897556249,0.47010609080532134,-0.03212892744333096,0.3237664369124269,-0.7039230664205183,-0.30372981581819986,0.29436510731780724,1.3827901527630164,-0.7039230664205183,0.4409258805823772,-1.0188392846787804,0.5283374011848795,0.47010609080532134,0.615366695909301,1.9621626060274844,1.2707865591544374,0.6731783026903564
2,448
Positive regulation of neuron death
9
15
1.973117
0.048482
Q13155,O95831,Q07812,Q00535,P61081,P05198,P78362,P61586,P17655
Processes and pathways
GO Biological process
msigdb_gobp
573,81,485,370,314,463,597,25,367
81,2203,463,1049,367,1407,1318,595,314,25,597,370,485,573,925
1.660439474765213,-0.8605609719945663,0.5283374011848795,0.087264561932277,0.6442930758559092,-0.15232095828757117,-0.09212329847709767,0.4117021682718201,0.730826559921213,2.581598099731636,0.4117021682718201,0.6442930758559092,0.4992431492624739,0.4409258805823772,0.17630258634391707
2,448
Stress granule assembly
9
14
1.971864
0.048625
Q8N543,Q9Y5A9,Q9Y520,Q8WWM7,P26196,P05198,Q14011,Q14157,O75534
Processes and pathways
GO Biological process
msigdb_gobp
330,236,506,539,412,463,150,122,647
1399,647,463,412,1372,924,150,122,881,330,539,723,506,236
-0.15232095828757117,0.3531228099863507,0.5283374011848795,0.5863988415320117,-0.12219648225605645,0.17630258634391707,1.1864163358736073,1.298839486996753,0.2058875754695338,0.7020226932379363,0.47010609080532134,0.3237664369124269,0.4992431492624739,0.9028157215260153
2,448
Molecular function regulator
80
223
1.965845
0.049317
P02656,P04792,P04083,P43490,O14786,O95373,P61586,P11233,Q8NFQ8,P14174,Q04917,Q99460,Q9BTT0,Q9UL46,Q15257,P61201,P54619,P55010,P14635,P31689,P41440,Q96KC8,Q86XL3,P60953,P35237,Q6IAA8,Q69YN2,Q9NWX6,Q9UMX5,P80303,Q15436,Q8N6T3,Q01105,Q9Y376,P40616,Q02818,Q8TC07,P61927,P55145,P51858,Q15042,P25685,O14745,O75592,P20339,O00273,O95684,O43242,Q9NR50,P49354,P0DP25,P23381,O60343,P29692,P20810,P52565,O14737,Q9H6Z4,Q9H3U1,Q9P258,Q9UI10,P17931,Q00535,P46777,P11802,Q92530,Q13200,Q9Y2L1,Q9UQ13,O43768,P30626,O60256,P18085,P43487,Q9BTW9,P24534,P04406,Q15008,Q15418,Q06323
Functions
GO Molecular function
msigdb_gomf
2,6,15,17,508,511,25,517,30,35,572,581,582,588,55,571,568,62,555,558,71,602,600,595,88,633,631,102,106,107,123,144,154,170,166,182,186,192,191,199,209,208,207,219,230,226,228,227,245,242,240,274,288,292,290,326,322,357,355,360,379,368,370,369,366,397,390,427,426,407,413,429,433,435,476,466,481,488,489,531
902,226,606,1347,1766,1399,322,207,508,1090,1349,2172,227,407,1951,429,288,868,1952,219,1953,1835,511,1619,228,2,954,15,481,2203,6,1687,2430,910,1988,1771,2439,1048,1002,1172,653,240,2387,654,517,366,1689,1174,1623,35,555,368,433,2114,1405,230,290,1005,274,466,208,292,2225,1878,775,618,961,1921,413,657,558,1455,88,1364,2116,166,71,435,17,1694,369,964,1459,242,1060,1695,1729,1100,2068,1319,1995,1227,199,326,741,1926,568,1141,62,1368,191,1842,1541,595,744,571,745,969,25,2256,192,783,1371,1586,1882,1628,1415,660,2361,1066,1698,661,1104,107,370,839,154,786,182,572,531,2333,1069,1812,701,1417,626,390,703,1507,841,1150,2212,976,843,706,488,2157,209,55,1078,489,123,1469,845,1382,979,629,1932,712,631,633,600,1472,1330,932,144,30,186,397,797,755,982,983,933,1749,2278,602,1432,1390,2134,581,2303,1750,1200,2281,582,476,1251,1160,1558,355,357,2085,1204,1437,2014,245,102,1295,1830,1481,2243,360,676,1121,989,1122,379,764,862,2413,588,2346,106,2220,1396,426,427,170,1609,727,1798
0.17630258634391707,0.9028157215260153,0.38243459835151017,-0.12219648225605645,-0.42583141250889395,-0.15232095828757117,0.7020226932379363,0.9598347398148359,0.47010609080532134,0.05748948699344504,-0.12219648225605645,-0.8291051207987041,0.9028157215260153,0.5863988415320117,-0.5797340545401417,0.5573891868193322,0.7595902108481608,0.2058875754695338,-0.5797340545401417,0.9313443171057458,-0.5797340545401417,-0.4872189313453426,0.47010609080532134,-0.30372981581819986,0.9028157215260153,6.997268324204374,0.14667069399718627,4.161025061636598,0.4992431492624739,-0.8605609719945663,5.931560240339164,-0.364669859579678,-3.0085610162180214,0.17630258634391707,-0.6106905307608944,-0.42583141250889395,-4.019164360328271,0.087264561932277,0.11699149062391306,-0.002206819462379813,0.3531228099863507,0.8742486728862037,-1.504130786089521,0.3531228099863507,0.47010609080532134,0.6442930758559092,-0.364669859579678,-0.002206819462379813,-0.30372981581819986,2.3409658129140403,0.4409258805823772,0.6442930758559092,0.5573891868193322,-0.7663872448501347,-0.15232095828757117,0.9028157215260153,0.7595902108481608,0.11699149062391306,0.7883139498979853,0.5283374011848795,0.9598347398148359,0.7595902108481608,-0.8920824087947153,-0.5179988657470733,0.2649184437199032,0.38243459835151017,0.14667069399718627,-0.5488370384270144,0.5863988415320117,0.3531228099863507,0.4409258805823772,-0.182497206611748,1.522027929261891,-0.12219648225605645,-0.7663872448501347,1.1017238127490079,1.7431006951795138,0.5573891868193322,3.856772038666039,-0.364669859579678,0.6442930758559092,0.14667069399718627,-0.182497206611748,0.8742486728862037,0.087264561932277,-0.364669859579678,-0.3952226726312979,0.05748948699344504,-0.7039230664205183,-0.09212329847709767,-0.6106905307608944,-0.03212892744333096,0.9882872661563274,0.7020226932379363,0.29436510731780724,-0.5488370384270144,0.4409258805823772,0.027665838086341914,1.798050804303417,-0.12219648225605645,1.0167021690167521,-0.4872189313453426,-0.24300698162028928,0.4117021682718201,0.29436510731780724,0.4409258805823772,0.29436510731780724,0.14667069399718627,2.581598099731636,-0.9236701828387313,1.0167021690167521,0.2649184437199032,-0.12219648225605645,-0.27334151033073334,-0.5179988657470733,-0.30372981581819986,-0.15232095828757117,0.3531228099863507,-1.2757154640498929,0.087264561932277,-0.364669859579678,0.3531228099863507,0.05748948699344504,1.3827901527630164,0.6442930758559092,0.23542606283924014,1.1582216374253231,0.2649184437199032,1.0450797177342925,0.4409258805823772,0.47010609080532134,-1.1467083845303592,0.087264561932277,-0.4564966412770062,0.3237664369124269,-0.15232095828757117,0.38243459835151017,0.615366695909301,0.3237664369124269,-0.21272571549189503,0.23542606283924014,0.027665838086341914,-0.8605609719945663,0.14667069399718627,0.23542606283924014,0.3237664369124269,0.4992431492624739,-0.7977141188950565,0.9598347398148359,1.8528768241204838,0.087264561932277,0.4992431492624739,1.298839486996753,-0.182497206611748,0.23542606283924014,-0.12219648225605645,0.14667069399718627,0.38243459835151017,-0.5488370384270144,0.3237664369124269,0.38243459835151017,0.38243459835151017,0.4117021682718201,-0.182497206611748,-0.09212329847709767,0.17630258634391707,1.2145752253051996,2.5016288793513897,1.0450797177342925,0.615366695909301,0.2649184437199032,0.29436510731780724,0.14667069399718627,0.14667069399718627,0.17630258634391707,-0.3952226726312979,-0.9553250615605502,0.4117021682718201,-0.15232095828757117,-0.12219648225605645,-0.7663872448501347,0.4409258805823772,-1.0188392846787804,-0.3952226726312979,-0.002206819462379813,-0.9553250615605502,0.4409258805823772,0.5283374011848795,-0.03212892744333096,0.027665838086341914,-0.24300698162028928,0.6731783026903564,0.6731783026903564,-0.7039230664205183,-0.002206819462379813,-0.15232095828757117,-0.6106905307608944,0.8742486728862037,1.4385861401124023,-0.06210093493456228,-0.4564966412770062,-0.182497206611748,-0.8920824087947153,0.6731783026903564,0.3531228099863507,0.05748948699344504,0.14667069399718627,0.05748948699344504,0.6442930758559092,0.29436510731780724,0.23542606283924014,-2.0720337721650783,0.4409258805823772,-1.1788542301541802,1.4107051071903693,-0.8605609719945663,-0.12219648225605645,0.5863988415320117,0.5863988415320117,1.1017238127490079,-0.27334151033073334,0.3237664369124269,-0.42583141250889395
2,448
Dendritic spine development
8
16
1.961342
0.049839
P18085,Q9UQB8,Q96HC4,P78344,Q00535,P60953,A0AVT1,O60678
Processes and pathways
GO Biological process
msigdb_gobp
433,134,580,529,370,595,302,218
302,218,433,1267,595,529,370,1544,1068,626,790,1152,1289,580,892,134
0.730826559921213,0.9313443171057458,0.5573891868193322,-0.06210093493456228,0.4117021682718201,0.47010609080532134,0.6442930758559092,-0.24300698162028928,0.087264561932277,0.38243459835151017,0.2649184437199032,0.027665838086341914,-0.06210093493456228,0.4409258805823772,0.2058875754695338,1.2707865591544374
2,448
Antigen processing ubiquitination proteasome degradation
51
77
4.723301
0.000002
P49720,O75832,Q15008,P49721,Q16763,O43242,Q9UNM6,P55786,P28072,P28074,O14818,P17980,P25788,P51665,P22314,Q7Z6Z7,Q9UIQ6,Q9Y508,Q92530,Q93034,P60900,P55036,P28070,P25787,Q9ULT8,P68036,Q9Y4B6,P62195,Q92990,Q99460,Q99436,P61088,O00231,Q8TBC4,P20618,Q9C0C9,P61086,Q96J02,Q15386,P61081,Q9UJX4,P25786,Q13867,Q13617,O94822,P25789,P62191,P61289,P52888,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,409,497,416,15,16,135,496,505,640,514,393,697,36,709,701,570,40,166,42,164,182,558,450,688,179,321,56,432,305,66,67,199,335,208,338,472,488,332,205,602,89,216,354,596,351,653,655
667,305,928,884,496,497,252,89,715,505,891,67,393,332,164,640,216,821,42,16,135,1744,1177,859,946,827,128,9,514,351,166,15,40,472,335,432,596,354,688,1185,653,558,1029,903,655,602,1347,205,738,1632,408,1553,338,409,1758,741,955,697,66,701,179,570,208,56,321,199,1927,36,1122,1569,488,1431,182,1002,416,450,709
0.4088101174779366,0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,1.6024811499433442,0.37455059026533083,0.5457559728599943,0.23741811556684678,1.8061474551769805,0.648370384959647,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,-0.48518476837761204,-0.0029385446148907503,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,0.7167357398101687,1.1262131892268594,4.198836571612469,2.48323710882666,0.5799697126669984,0.7509053294850906,0.6141744951918664,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.5115332103198423,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.4773013586496177,-0.14050815550820908,0.9898537517248991,0.37455059026533083,-0.3816652384302993,0.648370384959647,-0.3127085392865689,0.7509053294850906,0.648370384959647,-0.48518476837761204,0.37455059026533083,0.2031110399977868,0.4088101174779366,1.8739790092252244,0.4088101174779366,1.0921354984116292,0.5115332103198423,0.9898537517248991,2.1111705564621013,0.7850662756234686,1.0239558333863061,-0.6233729186226958,2.5845743832470656,0.06578463211521306,-0.3127085392865689,0.5799697126669984,-0.20935598039970602,1.0921354984116292,0.16879423156617618,0.648370384959647,0.6141744951918664,0.4088101174779366
2,448
Mapk family signaling cascades
43
76
4.219764
0.000024
P49720,Q15008,O75832,P49721,O43242,Q9UNM6,P28074,P28072,Q96S59,O14818,P17980,P30086,P25788,P30154,P51665,Q14738,Q92530,P60900,P55036,P28070,P25787,Q9UQ13,O60725,P30153,P62195,Q99460,Q99436,O43924,O00231,P20618,P27361,Q16181,P25786,Q13177,P49354,P25789,P06493,P17612,P18206,P62191,P61289,P62993,P25685
Processes and pathways
Reactome Pathways
msigdb_reactome
128,408,252,9,497,416,135,16,149,496,505,20,640,511,514,694,701,40,166,42,164,707,163,165,688,321,56,187,305,67,311,605,332,601,90,216,583,588,464,354,596,651,233
305,928,884,496,968,497,187,163,1575,252,1860,583,588,505,464,67,233,332,164,640,216,311,821,42,16,135,976,20,165,511,684,1788,2016,859,780,1140,946,1182,827,90,128,9,514,984,166,40,1226,596,1497,354,688,1185,651,1060,1101,1149,1029,601,903,1347,1151,694,408,605,701,800,149,56,321,758,2307,805,1431,416,707,807
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.16879423156617618,0.5457559728599943,1.058049730923791,1.1262131892268594,-0.3471813243224761,0.8874978505064713,-0.5888081853381918,0.4773013586496177,0.4773013586496177,0.5457559728599943,0.5799697126669984,1.8061474551769805,0.9216248161647249,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7850662756234686,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.16879423156617618,3.56138409547358,1.1262131892268594,0.5457559728599943,0.4088101174779366,-0.5197142211354513,-0.7271394986212955,0.271715534183546,0.3402816984562314,0.03142810909569467,0.2031110399977868,-0.0029385446148907503,0.3060033706040031,1.6024811499433442,1.262444229636026,4.73422667524134,0.5457559728599943,0.16879423156617618,1.1262131892268594,2.48323710882666,-0.03731541244345559,0.4773013586496177,-0.278246784654138,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.10013110654278463,0.06578463211521306,0.03142810909569467,0.1344676131809928,0.4773013586496177,0.23741811556684678,-0.14050815550820908,0.03142810909569467,0.4088101174779366,0.648370384959647,0.4773013586496177,0.4088101174779366,0.3402816984562314,1.1943445509410995,2.1111705564621013,0.7850662756234686,0.37455059026533083,-1.1433367450359972,0.3402816984562314,-0.20935598039970602,0.648370384959647,0.4088101174779366,0.3402816984562314
2,448
Deubiquitination
27
78
4.038641
0.000054
Q14258,P49720,Q8NB78,P45974,Q96K76,O75832,P49721,Q15008,P28074,P28072,P60900,P55036,P28070,P25787,P61586,Q99460,Q99436,O00231,P20618,P25786,Q9NXR7,P25789,Q96FW1,Q8TEY7,P62191,P54727,Q9Y5K5
Processes and pathways
Reactome Pathways
msigdb_reactome
258,128,5,255,143,252,9,408,135,16,40,166,42,164,46,321,56,305,67,332,230,216,98,357,354,236,133
305,928,884,496,710,497,1046,252,1820,2150,2270,583,1215,505,67,1262,332,164,640,216,821,42,16,135,859,945,946,1494,255,827,128,9,1310,514,828,236,166,1225,40,596,46,354,688,1185,1029,903,258,2255,1152,408,1231,1155,1673,657,1882,659,2101,5,357,701,1114,957,1886,98,143,56,321,1038,230,662,1431,416,1482,2004,1774,2087,1361,133
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.37455059026533083,0.5457559728599943,0.10013110654278463,0.8874978505064713,-0.554255323491472,-0.8656683146306153,-1.073844393574436,0.4773013586496177,-0.03731541244345559,0.5457559728599943,1.8061474551769805,-0.07170257917698318,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.2031110399977868,-0.278246784654138,0.8874978505064713,0.3060033706040031,1.262444229636026,4.73422667524134,-0.10610013099584205,0.5457559728599943,0.3060033706040031,0.9216248161647249,1.1262131892268594,-0.03731541244345559,2.48323710882666,0.4773013586496177,2.348031579016722,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.8874978505064713,-1.0391167407626585,0.03142810909569467,0.648370384959647,-0.03731541244345559,0.03142810909569467,-0.4161603820269248,0.44306035048595727,-0.5888081853381918,0.44306035048595727,-0.7963787260487372,5.801462288194559,0.7167357398101687,0.4088101174779366,0.06578463211521306,0.2031110399977868,-0.5888081853381918,1.5345340316692926,1.2283983252262376,2.1111705564621013,0.7850662756234686,0.1344676131809928,0.9557434311544011,0.44306035048595727,-0.20935598039970602,0.648370384959647,-0.24379596346019208,-0.6925384579151646,-0.48518476837761204,-0.7617528802884621,-0.14050815550820908,1.262444229636026
2,448
S phase
38
77
4.006608
0.000062
P49720,O75832,Q15008,P49721,Q16763,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P33991,P49736,P40937,P49643,P60900,P55036,P28070,P25787,P06400,P41440,Q99460,Q99436,O00231,P20618,P11802,P33993,Q9UJX4,P25786,Q9BRT9,P25789,P27694,P62191,P28340,P15927,P25205,Q14566,Q07864
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,409,497,416,135,16,496,505,395,513,512,400,40,166,42,164,287,54,321,56,305,67,195,313,488,332,224,216,348,354,101,347,465,523,519
305,928,884,496,497,2427,712,252,287,1305,195,680,347,505,67,465,332,164,640,216,348,821,42,16,135,101,1177,395,723,313,1580,1623,1179,859,552,512,54,946,827,1309,400,128,9,513,1052,1541,514,166,40,596,354,688,1185,653,1029,519,903,655,523,1594,408,409,993,873,701,56,321,224,1927,1892,1122,1569,488,1431,416,1524,2362
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-2.0508795111775275,0.37455059026533083,0.8874978505064713,0.8192186384010108,-0.10610013099584205,1.0239558333863061,0.4088101174779366,0.7167357398101687,0.5457559728599943,1.8061474551769805,0.5799697126669984,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7167357398101687,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.5005493340872977,-0.0029385446148907503,0.648370384959647,0.37455059026533083,0.7850662756234686,-0.3471813243224761,-0.3816652384302993,-0.0029385446148907503,0.271715534183546,0.5115332103198423,0.5457559728599943,2.1111705564621013,0.2031110399977868,0.3060033706040031,-0.10610013099584205,0.648370384959647,1.262444229636026,4.73422667524134,0.5457559728599943,0.10013110654278463,-0.3127085392865689,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.5457559728599943,0.23741811556684678,0.44306035048595727,0.5457559728599943,-0.3471813243224761,0.648370384959647,0.648370384959647,0.16879423156617618,0.271715534183546,0.4088101174779366,2.1111705564621013,0.7850662756234686,0.9557434311544011,-0.6233729186226958,-0.5888081853381918,0.06578463211521306,-0.3127085392865689,0.5799697126669984,-0.20935598039970602,0.648370384959647,-0.278246784654138,-1.3869375637035648
2,448
Mitotic g2 g2 m phases
48
74
3.894334
0.000098
Q15691,P49720,P14635,O75832,Q15008,P49721,P61981,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P30154,P25788,Q9BUF5,P68371,P51665,Q9H6D7,Q13409,Q92530,P60900,P55036,P28070,P25787,P30153,P07437,Q14203,P07900,Q99460,Q99436,O95684,O00231,P20618,Q96CW5,P61163,Q9BSJ2,P25786,P25789,P06493,P08238,P17612,P62191,P61289,P63151,P63208,Q13616,Q7Z460
Processes and pathways
Reactome Pathways
msigdb_reactome
130,128,253,252,408,9,405,497,416,135,16,496,505,511,640,276,406,514,161,562,701,40,166,42,164,165,288,433,546,321,56,188,305,67,613,336,619,332,216,583,585,588,354,596,652,653,655,658
305,928,884,496,2386,968,497,252,1532,188,2270,583,288,546,585,253,588,505,67,332,164,640,216,821,42,16,135,165,511,859,946,827,128,9,514,1586,166,40,1866,336,596,405,1497,354,688,730,1185,652,2381,653,406,1029,903,562,834,655,952,905,433,907,408,130,658,701,613,56,321,619,276,1924,161,1431,2385,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,-1.526392025421465,0.16879423156617618,0.5457559728599943,0.8874978505064713,-0.3127085392865689,1.058049730923791,-1.073844393574436,0.4773013586496177,0.8192186384010108,0.5115332103198423,0.4773013586496177,0.8874978505064713,0.4773013586496177,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.1262131892268594,0.5457559728599943,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,-0.3471813243224761,1.1262131892268594,2.48323710882666,-0.5888081853381918,0.7509053294850906,0.4773013586496177,0.648370384959647,-0.278246784654138,0.7167357398101687,0.4088101174779366,0.37455059026533083,-0.0029385446148907503,0.44306035048595727,-1.4915115757371213,0.44306035048595727,0.648370384959647,0.1344676131809928,0.23741811556684678,0.5115332103198423,0.3060033706040031,0.44306035048595727,0.2031110399977868,0.23741811556684678,0.6141744951918664,0.23741811556684678,0.648370384959647,1.262444229636026,0.44306035048595727,0.4088101174779366,0.4773013586496177,2.1111705564621013,0.7850662756234686,0.4773013586496177,0.8533624771761494,-0.6233729186226958,1.1602828560626173,-0.20935598039970602,-1.4915115757371213,0.648370384959647
2,448
Dna replication
45
73
3.814881
0.000136
P49720,O75832,Q16763,P49721,Q15008,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P33991,P25788,P49736,P40937,P51665,P49643,Q92530,P60900,P55036,P28070,P25787,P62195,P41440,O60684,Q99436,Q99460,P39748,O00231,P20618,P33993,Q9UJX4,P25786,Q9BRT9,P25789,P27694,P62191,P25205,P15927,P28340,P61289,Q14566,Q07864,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,409,9,408,497,416,135,16,496,505,395,640,513,512,514,400,701,40,166,42,164,688,54,672,56,321,552,305,67,313,488,332,224,216,348,354,465,347,101,596,523,519,653,655
305,928,884,496,497,2427,672,252,1305,680,347,2325,505,67,465,332,164,640,216,348,821,42,16,135,101,1177,395,723,313,1580,1623,1179,859,552,512,54,946,827,1309,400,128,9,513,1541,514,1338,166,40,596,354,688,1185,2397,653,1029,519,903,655,523,1064,408,409,701,56,321,224,1927,1122,1569,488,1431,416,2362
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-2.0508795111775275,0.4088101174779366,0.8874978505064713,-0.10610013099584205,0.4088101174779366,0.7167357398101687,-1.2128777512230653,0.5457559728599943,1.8061474551769805,0.5799697126669984,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7167357398101687,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.5005493340872977,-0.0029385446148907503,0.648370384959647,0.37455059026533083,0.7850662756234686,-0.3471813243224761,-0.3816652384302993,-0.0029385446148907503,0.271715534183546,0.5115332103198423,0.5457559728599943,2.1111705564621013,0.2031110399977868,0.3060033706040031,-0.10610013099584205,0.648370384959647,1.262444229636026,4.73422667524134,0.5457559728599943,-0.3127085392865689,0.5457559728599943,-0.14050815550820908,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-1.5961860445795646,0.44306035048595727,0.1344676131809928,0.5457559728599943,0.23741811556684678,0.44306035048595727,0.5457559728599943,0.10013110654278463,0.648370384959647,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,0.9557434311544011,-0.6233729186226958,0.06578463211521306,-0.3127085392865689,0.5799697126669984,-0.20935598039970602,0.648370384959647,-1.3869375637035648
2,448
Synthesis of dna
36
68
3.714776
0.000203
P49720,O75832,Q16763,P49721,Q15008,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P33991,P49736,P40937,P49643,P60900,P55036,P28070,P25787,P41440,Q99460,Q99436,O00231,P20618,P33993,Q9UJX4,P25786,Q9BRT9,P25789,P27694,P62191,P25205,P15927,P28340,Q14566,Q07864
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,409,9,408,497,416,135,16,496,505,395,513,512,400,40,166,42,164,54,321,56,305,67,313,488,332,224,216,348,354,465,347,101,523,519
305,928,884,496,497,2427,252,1305,680,347,505,67,465,332,164,640,216,348,821,42,16,135,101,1177,395,723,313,1580,1623,1179,859,552,512,54,946,827,1309,400,128,9,513,1541,514,166,40,596,354,688,1185,653,1029,519,903,655,523,408,409,701,56,321,224,1927,1122,1569,488,1431,416,2362
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-2.0508795111775275,0.8874978505064713,-0.10610013099584205,0.4088101174779366,0.7167357398101687,0.5457559728599943,1.8061474551769805,0.5799697126669984,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7167357398101687,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.5005493340872977,-0.0029385446148907503,0.648370384959647,0.37455059026533083,0.7850662756234686,-0.3471813243224761,-0.3816652384302993,-0.0029385446148907503,0.271715534183546,0.5115332103198423,0.5457559728599943,2.1111705564621013,0.2031110399977868,0.3060033706040031,-0.10610013099584205,0.648370384959647,1.262444229636026,4.73422667524134,0.5457559728599943,-0.3127085392865689,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.5457559728599943,0.23741811556684678,0.44306035048595727,0.5457559728599943,0.648370384959647,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,0.9557434311544011,-0.6233729186226958,0.06578463211521306,-0.3127085392865689,0.5799697126669984,-0.20935598039970602,0.648370384959647,-1.3869375637035648
2,448
Class i mhc mediated antigen processing presentation
55
93
3.660522
0.000252
Q15436,P49720,O75832,Q15008,P49721,Q16763,O43242,O94979,Q9UNM6,P55786,P28072,P28074,O14818,P17980,P25788,P51665,P22314,Q7Z6Z7,Q9UIQ6,Q9Y508,Q92530,Q93034,P60900,P55036,P28070,P25787,Q9ULT8,P68036,Q9Y4B6,P62195,Q92990,P09429,Q99436,O95486,Q99460,P61088,O00231,Q8TBC4,P20618,Q9C0C9,P61086,Q96J02,Q15386,P61081,Q9UJX4,P25786,Q13867,Q13617,O94822,P25789,P62191,P61289,P52888,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
259,128,252,408,9,409,497,499,416,15,16,135,496,505,640,514,393,697,36,709,701,570,40,166,42,164,182,558,450,688,179,547,56,173,321,432,305,66,67,199,335,208,338,472,488,332,205,602,89,216,354,596,351,653,655
667,1776,305,928,884,496,497,2194,252,89,715,499,173,1303,1404,547,2012,505,891,67,393,332,164,640,216,1826,2155,821,42,16,135,1744,2057,1177,859,946,827,128,9,2302,514,351,1456,166,15,2231,40,472,335,432,596,1831,354,688,1185,653,558,1029,903,655,602,1347,205,738,1632,408,1553,338,259,409,1758,741,955,697,66,701,179,570,208,56,321,199,1927,36,1122,1569,488,1431,182,1002,416,450,709
0.4088101174779366,-0.5197142211354513,0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-0.9350092561896616,0.8874978505064713,1.6024811499433442,0.37455059026533083,0.5457559728599943,1.0921354984116292,-0.10610013099584205,-0.20935598039970602,0.5115332103198423,-0.7271394986212955,0.5457559728599943,0.23741811556684678,1.8061474551769805,0.648370384959647,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,-0.554255323491472,-0.8656683146306153,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,-0.48518476837761204,-0.7617528802884621,-0.0029385446148907503,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,-1.1433367450359972,0.5457559728599943,0.7167357398101687,-0.24379596346019208,1.1262131892268594,4.198836571612469,-1.0044015886837547,2.48323710882666,0.5799697126669984,0.7509053294850906,0.6141744951918664,0.4773013586496177,-0.554255323491472,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.5115332103198423,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.4773013586496177,-0.14050815550820908,0.9898537517248991,0.37455059026533083,-0.3816652384302993,0.648370384959647,-0.3127085392865689,0.7509053294850906,0.8874978505064713,0.648370384959647,-0.48518476837761204,0.37455059026533083,0.2031110399977868,0.4088101174779366,1.8739790092252244,0.4088101174779366,1.0921354984116292,0.5115332103198423,0.9898537517248991,2.1111705564621013,0.7850662756234686,1.0239558333863061,-0.6233729186226958,2.5845743832470656,0.06578463211521306,-0.3127085392865689,0.5799697126669984,-0.20935598039970602,1.0921354984116292,0.16879423156617618,0.648370384959647,0.6141744951918664,0.4088101174779366
2,448
Mitotic g1 phase and g1 s transition
47
65
3.502609
0.000461
P49720,P00374,P14635,O75832,Q15008,P49721,P04183,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P33991,P25788,P30154,P49736,P51665,P49643,Q92530,P60900,P55036,P28070,P25787,P30153,P06400,P62195,Q99460,Q99436,O00231,P20618,P11802,P31350,P33993,P25786,P25789,P06493,Q07864,P27694,P62191,P25205,P15927,P61289,Q14566,P63151,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,4,253,252,408,9,636,497,416,135,16,496,505,395,640,511,513,514,400,701,40,166,42,164,165,287,688,321,56,305,67,195,312,313,332,216,583,519,348,354,465,347,596,523,652,653,655
305,928,884,496,497,2427,252,4,636,2337,287,583,1305,2314,195,680,253,347,505,67,465,332,164,640,216,348,821,42,16,135,165,511,312,395,723,313,859,946,827,1309,400,128,9,513,514,166,40,596,354,688,1185,652,653,1029,519,903,2373,655,523,408,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-2.0508795111775275,0.8874978505064713,5.801462288194559,0.44306035048595727,-1.2824665524224075,0.8192186384010108,0.4773013586496177,-0.10610013099584205,-1.1781012207532906,1.0239558333863061,0.4088101174779366,0.8874978505064713,0.7167357398101687,0.5457559728599943,1.8061474551769805,0.5799697126669984,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7167357398101687,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.1262131892268594,0.5457559728599943,0.7850662756234686,0.648370384959647,0.37455059026533083,0.7850662756234686,0.271715534183546,0.2031110399977868,0.3060033706040031,-0.10610013099584205,0.648370384959647,1.262444229636026,4.73422667524134,0.5457559728599943,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.44306035048595727,0.1344676131809928,0.5457559728599943,0.23741811556684678,-1.4566422868933564,0.44306035048595727,0.5457559728599943,0.648370384959647,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Neddylation
39
62
3.483273
0.000495
P49720,O75832,Q15008,P49721,O43242,Q86VP6,Q9UNM6,P28074,P28072,Q9UNS2,O14818,P17980,P25788,P51665,Q7L5N1,Q9UBW8,Q92530,Q93034,P55036,P28070,P25787,P60900,Q99460,Q99436,O00231,Q8TBC4,P20618,Q92905,P61081,P25786,Q13617,P25789,Q99627,P62191,P63208,P61289,P61964,Q13098,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,410,416,135,16,417,496,505,640,514,568,38,701,570,166,42,164,40,321,56,305,66,67,484,472,332,602,216,99,354,653,596,649,238,655
305,928,884,496,497,252,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,472,1269,596,649,354,688,1185,653,1029,238,903,737,655,602,1347,1379,408,2132,1553,911,1989,1235,568,410,66,701,484,570,56,321,99,918,1932,38,1431,416,417,925
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.5799697126669984,-0.07170257917698318,0.4773013586496177,0.44306035048595727,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.9216248161647249,0.23741811556684678,0.37455059026533083,0.44306035048595727,0.4773013586496177,-0.14050815550820908,-0.17492674178561746,0.648370384959647,-0.8310171614704213,-0.3127085392865689,0.23741811556684678,-0.6925384579151646,-0.03731541244345559,0.5115332103198423,0.648370384959647,1.8739790092252244,0.4088101174779366,0.5799697126669984,0.5115332103198423,2.1111705564621013,0.7850662756234686,1.5345340316692926,0.23741811556684678,-0.6233729186226958,2.517022513907188,-0.20935598039970602,0.648370384959647,0.648370384959647,0.23741811556684678
2,448
G2 m checkpoints
36
74
3.383805
0.000715
P49720,P63104,P14635,O75832,Q15008,P49721,P61981,O43242,Q9UQ84,Q9UNM6,Q04917,P28074,P28072,O14818,P17980,P33991,P49736,P40937,P60900,P55036,P28070,P25787,Q99460,Q99436,P61088,O00231,P20618,P33993,P25786,Q9NXR7,P25789,P27694,P62191,P25205,P15927,Q14566
Processes and pathways
Reactome Pathways
msigdb_reactome
128,518,253,252,408,9,405,497,12,416,136,135,16,496,505,395,513,512,40,166,42,164,321,56,432,305,67,313,332,230,216,348,354,465,347,523
305,928,884,496,497,2427,2269,252,936,1821,2270,583,253,347,2325,505,67,465,332,164,640,216,858,348,821,42,16,135,684,395,723,313,1580,1623,859,945,512,946,827,128,9,513,1024,1541,514,2422,166,40,432,596,405,354,688,730,1185,2397,518,136,1029,2320,903,523,1713,408,701,874,1722,56,321,1038,230,1431,416,12
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-2.0508795111775275,-1.073844393574436,0.8874978505064713,0.2031110399977868,-0.554255323491472,-1.073844393574436,0.4773013586496177,0.8874978505064713,0.7167357398101687,-1.2128777512230653,0.5457559728599943,1.8061474551769805,0.5799697126669984,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.271715534183546,0.7167357398101687,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.4088101174779366,0.648370384959647,0.37455059026533083,0.7850662756234686,-0.3471813243224761,-0.3816652384302993,0.271715534183546,0.2031110399977868,0.5457559728599943,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,0.1344676131809928,-0.3127085392865689,0.5457559728599943,-1.910788572894569,1.1262131892268594,2.48323710882666,0.6141744951918664,0.4773013586496177,0.648370384959647,0.7167357398101687,0.4088101174779366,0.37455059026533083,-0.0029385446148907503,-1.5961860445795646,0.5457559728599943,1.2283983252262376,0.1344676131809928,-1.1781012207532906,0.23741811556684678,0.5457559728599943,-0.45066685732428435,0.648370384959647,0.4088101174779366,0.271715534183546,-0.45066685732428435,2.1111705564621013,0.7850662756234686,0.1344676131809928,0.9557434311544011,-0.20935598039970602,0.648370384959647,4.533600706724896
2,448
Proteasome core complex
9
15
3.212399
0.001316
P20618,P49720,P60900,P49721,P28070,P25787,P28074,P28072,Q99436
Localization
GO Cellular component
msigdb_gocc
67,128,40,9,42,164,135,16,56
496,67,332,164,640,216,821,42,16,135,128,9,40,701,56
0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.262444229636026,4.73422667524134,2.48323710882666,0.4088101174779366,2.1111705564621013
2,448
Proteasome, subunit alpha/beta [IPR001353]
9
14
3.162202
0.001566
P20618,P49720,P60900,P49721,P28070,P25787,P28074,P28072,Q99436
Sequence
InterPro Family
interpro_family
67,128,40,9,42,164,135,16,56
496,67,332,164,640,216,821,42,16,135,128,9,40,56
0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.262444229636026,4.73422667524134,2.48323710882666,2.1111705564621013
2,448
Transcriptional regulation by runx2
33
51
3.161639
0.001569
P49720,P14635,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,P06400,Q99460,Q99436,O00231,P20618,P11802,P27361,P17931,P25786,P25789,P06493,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,253,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,287,321,56,305,67,195,311,310,332,216,583,354,596,653,655
305,928,884,496,497,252,287,583,195,253,310,505,67,332,164,640,216,311,821,42,16,135,976,859,1141,946,827,128,9,1052,514,166,40,596,354,688,1185,653,1029,1030,903,655,904,408,701,1073,56,321,1431,1002,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.8192186384010108,0.4773013586496177,1.0239558333863061,0.8874978505064713,0.7850662756234686,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7850662756234686,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.16879423156617618,0.271715534183546,0.03142810909569467,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.10013110654278463,0.5457559728599943,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.1344676131809928,0.23741811556684678,0.44306035048595727,0.23741811556684678,0.648370384959647,0.4088101174779366,0.10013110654278463,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.16879423156617618,0.648370384959647
2,448
Nucleophile aminohydrolases, N-terminal [IPR029055]
10
19
3.141668
0.00168
P20618,P49720,P08243,P60900,P49721,P28070,P25787,P28074,P28072,Q99436
Sequence
InterPro Superfamily
interpro_homologous_superfamily
67,128,69,40,9,42,164,135,16,56
496,69,67,332,164,640,216,821,42,16,135,128,9,40,1028,2355,1385,56,1481
0.5457559728599943,1.7382875171168664,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.262444229636026,4.73422667524134,2.48323710882666,0.1344676131809928,-1.352102319336769,-0.17492674178561746,2.1111705564621013,-0.24379596346019208
2,448
Signaling by wnt
35
75
3.061899
0.002199
P49720,P63104,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P09496,P30154,P25788,P17980,P51665,Q14738,Q92530,P60900,P55036,P28070,P25787,P30153,P61586,Q99460,Q99436,Q13363,O00231,P20618,P25786,P25789,P62191,P61289,P63208,Q13616,Q96QK1
Processes and pathways
Reactome Pathways
msigdb_reactome
128,518,252,408,9,497,416,135,16,496,637,511,640,505,514,694,701,40,166,42,164,165,46,321,56,61,305,67,332,216,354,596,653,655,264
305,928,884,496,968,497,1046,887,252,934,1697,851,637,1176,2325,505,1409,67,332,164,640,216,821,42,16,135,165,511,1863,859,946,827,1455,128,9,1052,1705,514,1542,166,1707,40,596,46,354,688,1185,2397,989,518,653,1271,734,1029,903,61,2373,655,1347,1914,694,408,2132,794,701,1512,264,56,321,758,1688,1431,416,1482,2087
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.16879423156617618,0.5457559728599943,0.10013110654278463,0.23741811556684678,0.8874978505064713,0.2031110399977868,-0.45066685732428435,0.271715534183546,0.44306035048595727,-0.0029385446148907503,-1.2128777512230653,0.5457559728599943,-0.20935598039970602,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.1262131892268594,0.5457559728599943,-0.5888081853381918,0.271715534183546,0.2031110399977868,0.3060033706040031,-0.24379596346019208,1.262444229636026,4.73422667524134,0.10013110654278463,-0.45066685732428435,0.5457559728599943,-0.3127085392865689,1.1262131892268594,-0.45066685732428435,2.48323710882666,0.4773013586496177,2.348031579016722,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-1.5961860445795646,0.16879423156617618,0.5457559728599943,0.44306035048595727,-0.07170257917698318,0.37455059026533083,0.1344676131809928,0.23741811556684678,2.009558259342313,-1.4566422868933564,0.44306035048595727,-0.14050815550820908,-0.6233729186226958,0.4088101174779366,0.648370384959647,-0.8310171614704213,0.3402816984562314,0.4088101174779366,-0.278246784654138,0.8874978505064713,2.1111705564621013,0.7850662756234686,0.37455059026533083,-0.4161603820269248,-0.20935598039970602,0.648370384959647,-0.24379596346019208,-0.7617528802884621
2,448
Endopeptidase complex
22
47
3.043372
0.002339
P49720,O75832,Q15008,P49721,P28074,P28072,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q15386,P25786,O43396,P25789,P62191,P54727,Q5VYK3,Q9Y5K5
Localization
GO Cellular component
msigdb_gocc
128,252,408,9,135,16,40,166,42,164,321,56,305,67,338,332,92,216,354,236,261,133
305,928,884,496,497,92,252,1860,1016,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,828,236,166,1225,40,596,354,688,1185,1029,903,408,338,657,261,701,1074,56,321,1431,416,133
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,1.5685112886631114,0.8874978505064713,-0.5888081853381918,0.1344676131809928,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,0.3060033706040031,0.9216248161647249,1.1262131892268594,-0.03731541244345559,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.7509053294850906,0.44306035048595727,0.8874978505064713,0.4088101174779366,0.10013110654278463,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647,1.262444229636026
2,448
Gtpase binding
36
71
3.025684
0.002481
Q9NUQ9,Q16513,P50395,O15397,Q8IWJ2,Q96S59,P09496,Q13464,Q13576,Q8TEX9,Q9HAV4,O00429,O43592,P07900,O00471,Q15904,P43487,O43924,P31150,Q92974,Q9UIA9,Q9P258,P16989,O75592,Q13177,O00410,Q9Y2A7,O60610,O95373,Q8TEY7,Q12904,Q7L576,P55060,Q9P2R3,Q9H4M9,Q92973
Functions
GO Molecular function
msigdb_gomf
537,792,646,249,412,149,637,563,33,300,704,669,51,546,670,319,190,187,550,748,624,622,78,88,601,578,764,579,214,357,735,527,237,389,384,532
1253,578,669,670,968,249,51,1210,187,579,88,214,938,851,1213,546,637,78,855,1137,550,1092,190,1495,1182,1747,646,1864,237,1340,1866,1314,1060,735,601,563,1377,33,1064,991,1106,319,792,1350,527,412,1071,300,357,532,748,1725,800,149,384,704,1357,1773,537,622,389,1296,624,1041,1429,1651,764,1734,1973,1081,926
-0.07170257917698318,0.4773013586496177,0.4088101174779366,0.4088101174779366,0.16879423156617618,0.8874978505064713,2.1788783058987153,-0.03731541244345559,1.058049730923791,0.4773013586496177,1.6024811499433442,0.9557434311544011,0.2031110399977868,0.271715534183546,-0.03731541244345559,0.5115332103198423,0.44306035048595727,1.6703988622284125,0.271715534183546,0.03142810909569467,0.5115332103198423,0.06578463211521306,1.058049730923791,-0.278246784654138,-0.0029385446148907503,-0.48518476837761204,0.44306035048595727,-0.5888081853381918,0.9216248161647249,-0.14050815550820908,-0.5888081853381918,-0.10610013099584205,0.10013110654278463,0.37455059026533083,0.4773013586496177,0.5115332103198423,-0.17492674178561746,2.6183409124581645,0.10013110654278463,0.16879423156617618,0.06578463211521306,0.7850662756234686,0.3402816984562314,-0.14050815550820908,0.5457559728599943,0.648370384959647,0.10013110654278463,0.8192186384010108,0.7167357398101687,0.5457559728599943,0.37455059026533083,-0.45066685732428435,0.3402816984562314,1.1943445509410995,0.6825574455888234,0.4088101174779366,-0.14050815550820908,-0.48518476837761204,0.5457559728599943,0.4773013586496177,0.6825574455888234,-0.07170257917698318,0.4773013586496177,0.1344676131809928,-0.20935598039970602,-0.3816652384302993,0.37455059026533083,-0.45066685732428435,-0.6579496374044261,0.10013110654278463,0.23741811556684678
2,448
Threonine type peptidase activity
7
10
3.016326
0.002559
P20618,P49720,P49721,P28070,P28074,P28072,Q99436
Functions
GO Molecular function
msigdb_gomf
67,128,9,42,135,16,56
67,216,42,16,135,128,9,1385,56,1481
1.8061474551769805,0.9557434311544011,2.4156471929658223,4.131824187305753,1.2283983252262376,1.262444229636026,4.73422667524134,-0.17492674178561746,2.1111705564621013,-0.24379596346019208
2,448
Separation of sister chromatids
34
87
3.00578
0.002649
Q15691,Q9Y266,P49720,O75832,Q15008,P49721,Q16763,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P30154,Q9BUF5,P68371,P51665,Q13409,O43264,P60900,P55036,P28070,P30153,P25787,Q99460,Q99436,O00231,P20618,Q9UJX4,P25786,P25789,P62191,O60566,Q2NKX8
Processes and pathways
Reactome Pathways
msigdb_reactome
130,540,128,252,408,9,409,497,416,135,16,496,505,511,276,406,514,562,282,40,166,42,165,164,321,56,305,67,488,332,216,354,100,525
1206,305,928,884,496,968,970,497,282,1084,1045,712,100,252,505,67,332,164,640,216,821,42,16,135,165,511,1177,859,946,1495,827,128,9,1747,514,1791,1586,166,1056,40,596,354,688,1185,2381,406,1029,1548,903,562,952,905,907,1594,694,1796,408,130,409,993,525,2025,658,873,1112,1243,1388,701,2383,56,321,1287,276,1924,1769,1927,2222,1892,622,1122,1569,488,1431,416,1524,540,576
-0.03731541244345559,0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.16879423156617618,0.16879423156617618,0.5457559728599943,0.8192186384010108,0.06578463211521306,0.10013110654278463,0.37455059026533083,1.5005493340872977,0.8874978505064713,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,1.1262131892268594,0.5457559728599943,-0.0029385446148907503,0.271715534183546,0.2031110399977868,-0.278246784654138,0.3060033706040031,1.262444229636026,4.73422667524134,-0.48518476837761204,0.5457559728599943,-0.5197142211354513,-0.3471813243224761,1.1262131892268594,0.10013110654278463,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-1.4915115757371213,0.648370384959647,0.1344676131809928,-0.3127085392865689,0.23741811556684678,0.5115332103198423,0.2031110399977868,0.23741811556684678,0.23741811556684678,-0.3471813243224761,0.4088101174779366,-0.5197142211354513,0.648370384959647,1.262444229636026,0.648370384959647,0.16879423156617618,0.5457559728599943,-0.7271394986212955,0.44306035048595727,0.271715534183546,0.06578463211521306,-0.03731541244345559,-0.17492674178561746,0.4088101174779366,-1.4915115757371213,2.1111705564621013,0.7850662756234686,-0.07170257917698318,0.8533624771761494,-0.6233729186226958,-0.48518476837761204,-0.6233729186226958,-0.9696990541422212,-0.5888081853381918,0.4773013586496177,0.06578463211521306,-0.3127085392865689,0.5799697126669984,-0.20935598039970602,0.648370384959647,-0.278246784654138,0.5457559728599943,0.5115332103198423
2,448
Proteasome complex
22
45
3.000436
0.002696
P49720,O75832,Q15008,P49721,P28074,P28072,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q15386,P25786,O43396,P25789,P62191,P54727,Q5VYK3,Q9Y5K5
Localization
GO Cellular component
msigdb_gocc
128,252,408,9,135,16,40,166,42,164,321,56,305,67,338,332,92,216,354,236,261,133
305,928,884,496,497,92,252,1860,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,828,236,166,1225,40,596,354,688,1185,1029,903,408,338,657,261,701,56,321,1431,416,133
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,1.5685112886631114,0.8874978505064713,-0.5888081853381918,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,0.3060033706040031,0.9216248161647249,1.1262131892268594,-0.03731541244345559,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.1344676131809928,0.23741811556684678,0.648370384959647,0.7509053294850906,0.44306035048595727,0.8874978505064713,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647,1.262444229636026
2,448
Signaling by hedgehog
32
53
2.999101
0.002708
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,Q9BUF5,P25788,P68371,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,O00231,P20618,Q96J02,P25786,P10644,P25789,P17612,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,276,640,406,514,701,40,166,42,164,321,56,305,67,208,332,330,216,588,354,596,653,655
305,928,884,496,497,252,1405,330,1577,588,505,67,332,164,640,216,821,42,16,135,859,946,827,1455,128,9,1052,514,166,1225,40,596,354,688,1185,653,406,1029,903,655,1347,952,408,794,701,208,56,321,276,1924,1359,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,-0.20935598039970602,0.7509053294850906,-0.3471813243224761,0.4773013586496177,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,-0.24379596346019208,1.262444229636026,4.73422667524134,0.10013110654278463,0.5457559728599943,1.1262131892268594,-0.03731541244345559,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.648370384959647,0.1344676131809928,0.23741811556684678,0.44306035048595727,-0.14050815550820908,0.2031110399977868,0.648370384959647,0.3402816984562314,0.4088101174779366,0.9898537517248991,2.1111705564621013,0.7850662756234686,0.8533624771761494,-0.6233729186226958,-0.14050815550820908,-0.20935598039970602,0.648370384959647
2,448
Translation regulator activity
50
75
2.958059
0.003096
Q9Y6M1,P00374,Q04637,P49588,O15371,O43432,Q9NZI8,P20042,P26641,Q7L2H7,P29692,P11940,Q13144,P55884,Q06787,Q9Y450,O60841,P06730,P55010,P05198,O75822,O00178,Q9UBQ5,P60228,P13639,P24534,O00425,Q92616,P60842,P23588,Q8NE71,Q92905,P49770,Q9Y262,Q92879,P19525,P34896,Q13347,Q7Z478,Q14011,Q9BY44,Q05639,Q9NR50,O00303,P62495,O15372,Q7L576,P43897,Q14232,P78344
Functions
GO Molecular function
msigdb_gomf
666,4,379,645,628,629,805,774,641,21,510,772,561,402,168,449,418,545,55,544,420,57,324,315,682,683,810,611,556,426,610,484,314,211,340,820,824,868,872,603,878,865,105,847,863,711,527,860,908,654
57,847,810,628,711,629,1044,418,1211,420,4,2337,544,545,772,682,941,820,774,426,683,641,1905,510,824,2058,1138,1583,860,1142,2019,645,314,898,1414,55,402,1663,1458,315,556,986,863,1147,654,1059,379,865,168,561,868,603,906,2426,908,1501,1153,1035,21,527,995,872,610,611,340,484,1888,878,105,805,324,1295,211,449,666
2.043435831472084,0.271715534183546,0.3060033706040031,0.44306035048595727,0.37455059026533083,0.44306035048595727,0.10013110654278463,0.6141744951918664,-0.03731541244345559,0.6141744951918664,5.801462288194559,-1.2824665524224075,0.5115332103198423,0.5115332103198423,0.3402816984562314,0.4088101174779366,0.2031110399977868,0.3060033706040031,0.3402816984562314,0.6141744951918664,0.4088101174779366,0.44306035048595727,-0.6233729186226958,0.5457559728599943,0.3060033706040031,-0.7617528802884621,0.03142810909569467,-0.3471813243224761,0.271715534183546,0.03142810909569467,-0.7271394986212955,0.44306035048595727,0.7850662756234686,0.23741811556684678,-0.20935598039970602,2.1111705564621013,0.648370384959647,-0.4161603820269248,-0.24379596346019208,0.7850662756234686,0.5115332103198423,0.16879423156617618,0.271715534183546,0.03142810909569467,0.44306035048595727,0.10013110654278463,0.6825574455888234,0.271715534183546,1.1262131892268594,0.5115332103198423,0.271715534183546,0.4773013586496177,0.23741811556684678,-2.0158417973421328,0.23741811556684678,-0.278246784654138,0.03142810909569467,0.1344676131809928,3.494172256495323,0.5457559728599943,0.16879423156617618,0.271715534183546,0.4773013586496177,0.4773013586496177,0.7509053294850906,0.5799697126669984,-0.5888081853381918,0.271715534183546,1.5005493340872977,0.3402816984562314,0.7850662756234686,-0.07170257917698318,0.9898537517248991,0.6141744951918664,0.44306035048595727
2,448
C type lectin receptors clrs
32
44
2.954272
0.003134
P49720,O75832,Q15008,P49721,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P25788,P51665,Q92530,P60900,P55036,P28070,P25787,Q99460,Q99436,P61088,O00231,Q8TBC4,P20618,P61081,P25786,Q13177,P25789,P17612,P62191,P61289,P63208,Q13616
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,497,416,135,16,496,505,640,514,701,40,166,42,164,321,56,432,305,66,67,472,332,601,216,588,354,596,653,655
305,928,884,496,497,252,588,505,67,332,164,640,216,821,42,16,135,859,946,827,128,9,514,166,40,472,432,596,354,688,1185,653,1029,601,903,655,408,1673,66,701,56,321,1431,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,0.8874978505064713,0.4773013586496177,0.5457559728599943,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.271715534183546,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.5457559728599943,1.1262131892268594,2.48323710882666,0.5799697126669984,0.6141744951918664,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,0.1344676131809928,0.4773013586496177,0.23741811556684678,0.44306035048595727,0.648370384959647,-0.4161603820269248,1.8739790092252244,0.4088101174779366,2.1111705564621013,0.7850662756234686,-0.20935598039970602,0.648370384959647
2,448
Alzheimers disease
21
74
2.947316
0.003205
P49720,Q15008,P49721,Q9UNM6,P28074,P28072,Q9BUF5,Q00535,P60900,P55036,P28070,P25787,P33176,P07437,Q99460,Q99436,P20618,P27361,P25786,P25789,P62191
Processes and pathways
WikiPathways
msigdb_wp
128,408,9,416,135,16,276,157,40,166,42,164,291,288,321,56,67,311,332,216,354
928,884,930,496,497,1173,582,2371,1698,544,940,288,503,1337,1902,1215,2176,1016,505,820,1409,67,1262,332,164,640,216,311,821,42,16,135,976,1981,291,1863,859,1222,946,1494,827,1455,644,128,9,1052,514,166,40,354,688,1185,1271,406,157,1101,951,1102,903,737,952,408,657,1677,2220,56,321,615,2237,276,1924,2263,416,2004
0.2031110399977868,0.23741811556684678,0.2031110399977868,0.5457559728599943,0.5457559728599943,-0.0029385446148907503,0.4773013586496177,-1.4566422868933564,-0.45066685732428435,0.5115332103198423,0.2031110399977868,0.8192186384010108,0.5457559728599943,-0.14050815550820908,-0.6233729186226958,-0.03731541244345559,-0.9003323161906817,0.1344676131809928,0.5457559728599943,0.3060033706040031,-0.20935598039970602,1.8061474551769805,-0.07170257917698318,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7850662756234686,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.16879423156617618,-0.6925384579151646,0.8192186384010108,-0.5888081853381918,0.271715534183546,-0.03731541244345559,0.2031110399977868,-0.278246784654138,0.3060033706040031,-0.24379596346019208,0.44306035048595727,1.262444229636026,4.73422667524134,0.10013110654278463,0.5457559728599943,1.1262131892268594,2.48323710882666,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,-0.07170257917698318,0.648370384959647,1.1602828560626173,0.06578463211521306,0.2031110399977868,0.06578463211521306,0.23741811556684678,0.37455059026533083,0.2031110399977868,0.648370384959647,0.44306035048595727,-0.4161603820269248,-0.9696990541422212,2.1111705564621013,0.7850662756234686,0.4773013586496177,-1.0044015886837547,0.8533624771761494,-0.6233729186226958,-1.0391167407626585,0.648370384959647,-0.6925384579151646
2,448
Intracellular signaling by second messengers
34
72
2.944468
0.003235
P49720,O75832,Q15008,P49721,Q86YP4,O43242,Q9UNM6,P28074,P28072,O14818,P17980,P30154,P25788,P51665,Q14738,Q92530,P60900,P55036,P28070,P25787,P30153,Q99460,Q99436,O00231,Q96B36,P20618,P27361,P25786,P10644,P25789,P17612,P62191,P61289,P62993
Processes and pathways
Reactome Pathways
msigdb_reactome
128,252,408,9,411,497,416,135,16,496,505,511,640,514,694,701,40,166,42,164,165,321,56,305,612,67,311,332,330,216,588,354,596,651
305,928,884,496,497,1940,252,1366,769,2270,330,1577,2056,588,505,1409,67,332,164,640,216,311,821,42,16,135,976,165,511,859,1222,946,827,128,9,1052,514,861,166,40,596,354,688,1185,651,1271,1415,1149,1029,903,1631,2373,694,1188,408,2186,1989,1350,411,1721,701,2030,1886,612,56,321,758,2307,1001,1431,1002,416
0.7850662756234686,0.2031110399977868,0.23741811556684678,0.5457559728599943,0.5457559728599943,-0.6579496374044261,0.8874978505064713,-0.17492674178561746,0.3402816984562314,-1.073844393574436,0.7509053294850906,-0.3471813243224761,-0.7617528802884621,0.4773013586496177,0.5457559728599943,-0.20935598039970602,1.8061474551769805,0.7509053294850906,1.1262131892268594,0.44306035048595727,0.9557434311544011,0.7850662756234686,0.3060033706040031,2.4156471929658223,4.131824187305753,1.2283983252262376,0.16879423156617618,1.1262131892268594,0.5457559728599943,0.271715534183546,-0.03731541244345559,0.2031110399977868,0.3060033706040031,1.262444229636026,4.73422667524134,0.10013110654278463,0.5457559728599943,0.271715534183546,1.1262131892268594,2.48323710882666,0.4773013586496177,0.7167357398101687,0.4088101174779366,-0.0029385446148907503,0.44306035048595727,-0.07170257917698318,-0.20935598039970602,0.03142810909569467,0.1344676131809928,0.23741811556684678,-0.3816652384302993,-1.4566422868933564,0.4088101174779366,-0.0029385446148907503,0.648370384959647,-0.9003323161906817,-0.6925384579151646,-0.14050815550820908,0.648370384959647,-0.45066685732428435,0.4088101174779366,-0.7271394986212955,-0.5888081853381918,0.4773013586496177,2.1111705564621013,0.7850662756234686,0.37455059026533083,-1.1433367450359972,0.16879423156617618,-0.20935598039970602,0.16879423156617618,0.648370384959647
2,448
Threonine type endopeptidase activity
7
8
2.942135
0.00326
P20618,P49720,P49721,P28070,P28074,P28072,Q99436
Functions
GO Molecular function
msigdb_gomf
67,128,9,42,135,16,56
67,216,42,16,135,128,9,56
1.8061474551769805,0.9557434311544011,2.4156471929658223,4.131824187305753,1.2283983252262376,1.262444229636026,4.73422667524134,2.1111705564621013
2,448
Proteasome beta-type subunit, conserved site [IPR016050]
7
8
2.942135
0.00326
P20618,P49720,P49721,P28070,P28074,P28072,Q99436
Sequence
InterPro Conserved site
interpro_conserved_site
67,128,9,42,135,16,56
67,216,42,16,135,128,9,56
1.8061474551769805,0.9557434311544011,2.4156471929658223,4.131824187305753,1.2283983252262376,1.262444229636026,4.73422667524134,2.1111705564621013
2,448