term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein localization to mitochondrion | 26 | 68 | 2.67315 | 0.007514 | P51572,O14925,Q9Y6C9,P49257,Q99797,P30536,Q9NS69,O60830,O14737,O43615,Q9Y584,O00165,O95429,O95831,Q99595,Q5JRX3,O60220,P62072,Q15388,Q8TB36,Q9Y5J9,Q9Y5J7,Q9P0J0,P55786,Q8N8Q8,Q15070 | Processes and pathways | GO Biological process | msigdb_gobp | 256,254,388,641,526,521,16,18,414,541,38,298,309,54,63,458,578,80,594,348,611,350,610,359,106,120 | 298,1029,3006,1832,414,254,541,578,18,2086,2652,1084,309,2346,54,1037,1801,1803,3321,984,2657,2306,1767,521,1638,3101,641,1743,256,1440,359,80,2501,908,676,1137,120,594,2587,952,817,458,2912,106,348,1782,2068,63,526,3176,1102,1576,16,3155,610,2560,2746,1268,1428,3028,840,1080,1108,38,350,611,761,388 | 1.3226108940757686,0.23226835470484916,-0.8501127548246629,-0.21696018972606024,1.0169809765122253,1.464604471440723,0.7829774041493419,0.7127631981492363,3.533699034108947,-0.32958192020084226,-0.6104587700422,0.20213885674598203,1.2965110453880544,-0.4439443859497023,2.8876479191575553,0.23226835470484916,-0.20101010976855774,-0.20101010976855774,-1.4294716859918053,0.26227740933927773,-0.6104587700422,-0.4274980724879269,-0.18509422483019053,0.8108826859948203,-0.12176944730407814,-0.9376441237503343,0.6276405919776796,-0.16921237464871447,1.464604471440723,-0.012231339448816497,1.1646687956946997,2.6161644885369233,-0.5267307699032723,0.3367799639890156,0.5847183748800465,0.1718878508968803,2.1381080960394128,0.6986422043532152,-0.5601076639663766,0.3070674535939185,0.42522051928811844,0.9352077032562823,-0.763618598810603,2.254579138715145,1.2044591471962716,-0.18509422483019053,-0.31338788818645713,2.844825243700939,0.8108826859948203,-1.0440899073566592,0.20213885674598203,-0.07462717308757696,3.5926238292445705,-1.0084345585434802,0.684494911792463,-0.5434002923310789,-0.6442189217896607,0.09572162059983903,0.003286382816216437,-0.8501127548246629,0.41055230371744406,0.21721872733739006,0.20213885674598203,3.139895912874602,1.2044591471962716,0.684494911792463,0.49813702297415485,1.0710152307117244 | 3,417 |
Electron transport chain oxphos system in mitochondria | 22 | 52 | 2.662034 | 0.007767 | P13073,P00846,P12235,P03886,P24539,O43676,O95168,P00403,P51970,O75964,O95139,P56134,P22695,O75880,O43674,P14406,P20674,P25705,P12236,Q7KZN9,Q9Y6M9,P21912 | Processes and pathways | WikiPathways | msigdb_wp | 255,5,519,25,289,37,556,175,558,53,185,449,206,82,213,93,603,477,613,496,515,378 | 3377,1431,1872,213,37,2200,1669,763,772,1360,82,1614,53,185,556,3346,1636,1133,175,5,25,889,621,2608,1111,519,613,255,93,1877,1060,3224,3311,603,378,206,289,477,3339,2436,2532,1952,3293,3326,558,449,906,2996,1044,496,1268,515 | -1.9777750442589752,-0.012231339448816497,-0.23294462613289643,1.6416384181662695,3.139895912874602,-0.3783778232336641,-0.13755014327896972,0.4836099334246191,0.46905485711054756,0.034225377321387807,2.582956910707055,-0.10602215649073785,2.8983179291537704,1.753353058227572,0.7549694526938922,-1.5818830601858436,-0.12176944730407814,0.1718878508968803,1.8024946555524302,4.150512780930534,3.334140571921885,0.3515923455547478,0.6561209993607429,-0.5768530736707557,0.18702860941006846,0.8108826859948203,0.6703212128832107,1.464604471440723,2.5049291611996107,-0.23294462613289643,0.21721872733739006,-1.134002123850734,-1.3918689663666952,0.684494911792463,1.097890201205585,1.6790550002814526,1.3615958927095713,0.8939906762605774,-1.543475472466397,-0.4935045244272046,-0.5434002923310789,-0.26501721992446775,-1.2987125719306165,-1.4483470542519512,0.7549694526938922,0.9488974456277595,0.3367799639890156,-0.8327318119520807,0.23226835470484916,0.8525498970089892,0.09572162059983903,0.8247970828574156 | 3,417 |
Abnormal retinal vascular morphology | 15 | 57 | 2.647133 | 0.008118 | P21964,P00846,P38435,Q96PY6,P21912,P06865,Q96S66,P10619,P07602,P17900,P03886,P16278,Q13510,Q9NZJ7,Q8NFV4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 66,5,421,400,378,144,405,85,23,221,25,373,61,343,191 | 3275,2820,1834,1835,2463,1669,2986,1918,3258,5,25,434,144,23,1490,3066,85,2495,2692,373,221,1920,2118,378,66,919,2436,1273,2309,2575,2090,421,3276,1956,1807,2725,2123,2477,699,642,61,2416,1157,777,2588,191,547,1542,2066,1656,2450,1049,400,405,343,2458,760 | -1.2433909693380374,-0.7122088737255577,-0.21696018972606024,-0.21696018972606024,-0.5100989092650228,-0.13755014327896972,-0.8327318119520807,-0.2489635815987443,-1.2250442111451176,4.150512780930534,3.334140571921885,0.9762036088666618,1.9720970491130785,3.3844919984080626,-0.04336396950002838,-0.9025053658548252,2.5607412932011338,-0.5267307699032723,-0.6273194417875337,1.1112924650776037,1.6040409488013108,-0.2489635815987443,-0.3458114723662479,1.097890201205585,2.790972813120915,0.32193837550732557,-0.4935045244272046,0.0803949197759099,-0.4274980724879269,-0.5601076639663766,-0.32958192020084226,1.003412645073793,-1.2433909693380374,-0.26501721992446775,-0.20101010976855774,-0.6442189217896607,-0.3458114723662479,-0.5100989092650228,0.5559678555775356,0.6276405919776796,2.855552391486076,-0.4769474308147848,0.15671644585303687,0.46905485711054756,-0.5601076639663766,1.7410191359493292,0.7829774041493419,-0.058979174610651705,-0.31338788818645713,-0.12176944730407814,-0.4935045244272046,0.23226835470484916,1.0575423433134081,1.0440457330659343,1.2308721605709914,-0.4935045244272046,0.49813702297415485 | 3,417 |
Protein localization | 31 | 79 | 2.641354 | 0.008258 | O14925,P12235,P50402,Q9NS69,O60830,O43615,P51648,Q9Y584,P09601,Q15067,P21796,O15254,Q99595,Q13505,Q5JRX3,O60220,P46379,P62072,P40855,Q9NX63,Q15388,Q8TB36,Q9Y5J9,Q9Y5J7,O43808,P25705,P12236,O00116,P06576,P05067,P49069 | Processes and pathways | Reactome Pathways | msigdb_reactome | 254,519,268,16,18,541,36,38,51,187,60,441,63,68,458,578,207,80,336,474,594,348,611,350,97,477,613,249,621,241,121 | 249,620,254,811,441,541,693,1034,97,578,18,1035,3187,1703,2086,2718,873,1613,2652,1037,2824,241,621,1171,3370,51,3321,519,613,2470,60,1174,477,1405,3389,2534,2166,336,207,121,268,947,36,1530,2697,2759,80,676,2174,1280,68,187,594,1470,952,458,1284,701,882,348,2332,63,3198,2556,3039,1576,16,474,940,2490,787,1428,2012,840,1108,38,350,611,761 | 1.4901437800337045,0.6561209993607429,1.464604471440723,0.42522051928811844,0.9625627156053822,0.7829774041493419,0.5559678555775356,0.23226835470484916,2.4599953722597876,0.7127631981492363,3.533699034108947,0.23226835470484916,-1.0799211761036647,-0.15336440011844105,-0.32958192020084226,-0.6442189217896607,0.3663756458799081,-0.10602215649073785,-0.6104587700422,0.23226835470484916,-0.7122088737255577,1.5155991816321197,0.6561209993607429,0.1415142579959687,-1.9371792171939057,2.9196154491336292,-1.4294716859918053,0.8108826859948203,0.6703212128832107,-0.5100989092650228,2.855552391486076,0.1415142579959687,0.8939906762605774,0.003286382816216437,-2.2474878163022267,-0.5434002923310789,-0.3620767158842694,1.24404475743253,1.6790550002814526,2.126365733026883,1.4261368498464053,0.3070674535939185,3.1502366120869385,-0.058979174610651705,-0.6273194417875337,-0.6611574063587524,2.6161644885369233,0.5847183748800465,-0.3620767158842694,0.0803949197759099,2.7367552921523206,1.753353058227572,0.6986422043532152,-0.027781407508477674,0.3070674535939185,0.9352077032562823,0.0803949197759099,0.5559678555775356,0.3663756458799081,1.2044591471962716,-0.4274980724879269,2.844825243700939,-1.0799211761036647,-0.5434002923310789,-0.8675351827166916,-0.07462717308757696,3.5926238292445705,0.9077544157121817,0.32193837550732557,-0.5100989092650228,0.46905485711054756,0.003286382816216437,-0.28110570611391306,0.41055230371744406,0.20213885674598203,3.139895912874602,1.2044591471962716,0.684494911792463,0.49813702297415485 | 3,417 |
Abnormality of the larynx | 13 | 53 | 2.611957 | 0.009003 | P21964,Q9UHX1,Q96PY6,Q96HY6,Q92804,P35637,P02545,P25054,Q9NZJ7,Q68CQ7,P07602,Q13510,Q15165 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 66,35,400,104,266,197,393,273,343,117,23,61,29 | 2820,3084,3354,3246,2796,2897,393,2526,23,2203,1058,650,3213,66,273,1527,197,1063,1993,2992,1994,923,1337,1276,2905,2725,2123,2315,1070,1680,951,61,1181,470,2218,29,2099,117,953,2284,1326,1656,266,2450,104,400,1631,343,2193,599,1266,35,1580 | -0.7122088737255577,-0.920053561687098,-1.6788137614948677,-1.1884897999995363,-0.6951521821407869,-0.763618598810603,1.0575423433134081,-0.5434002923310789,3.3844919984080626,-0.3783778232336641,0.21721872733739006,0.6133601781301887,-1.1159302783535316,2.790972813120915,1.4132716921952186,-0.058979174610651705,1.716292591643401,0.21721872733739006,-0.28110570611391306,-0.8327318119520807,-0.28110570611391306,0.32193837550732557,0.04964694067544423,0.0803949197759099,-0.763618598810603,-0.6442189217896607,-0.3458114723662479,-0.4274980724879269,0.21721872733739006,-0.13755014327896972,0.3070674535939185,2.855552391486076,0.1415142579959687,0.9077544157121817,-0.3783778232336641,3.2936329120887344,-0.32958192020084226,2.1498329700173007,0.3070674535939185,-0.41108832580523696,0.06503674048205203,-0.12176944730407814,1.43898064729436,-0.4935045244272046,2.3006903741988816,1.0575423433134081,-0.10602215649073785,1.2308721605709914,-0.3620767158842694,0.6986422043532152,0.09572162059983903,3.1708783290039375,-0.07462717308757696 | 3,417 |
Mitochondrial transport | 36 | 92 | 2.5963 | 0.009423 | P51572,O14925,P00846,Q99797,Q96EK5,P30536,P12235,Q9NS69,O60830,O14737,P24539,O43615,Q9Y584,O00165,O75964,O95429,O95831,Q99595,P56134,Q6NUK1,Q9UBX3,Q5JRX3,O60220,P62072,Q15388,Q8TB36,Q9Y5J9,P45880,Q9Y5J7,Q9P0J0,P25705,O43772,P55786,Q8N8Q8,P06576,Q15070 | Processes and pathways | GO Biological process | msigdb_gobp | 256,254,5,526,399,521,519,16,18,414,289,541,38,298,53,309,54,63,449,199,73,458,578,80,594,348,611,92,350,610,477,483,359,106,621,120 | 298,1029,414,254,541,483,578,18,1703,2086,1614,53,2652,1084,309,2346,54,1037,5,2526,889,621,1801,2568,3321,519,3224,2306,1231,289,477,2573,1767,521,3101,1952,3011,92,3293,1178,641,1743,1844,256,1440,359,449,906,80,2501,908,676,1137,120,594,2587,952,817,458,199,2912,2393,2135,106,348,1782,399,1787,2068,63,526,3176,1102,1576,2596,16,610,2560,2746,73,1268,787,1079,1428,3028,840,1080,1108,38,350,611,761 | 1.3226108940757686,0.23226835470484916,1.0169809765122253,1.464604471440723,0.7829774041493419,0.8802020758474672,0.7127631981492363,3.533699034108947,-0.15336440011844105,-0.32958192020084226,-0.10602215649073785,2.8983179291537704,-0.6104587700422,0.20213885674598203,1.2965110453880544,-0.4439443859497023,2.8876479191575553,0.23226835470484916,4.150512780930534,-0.5434002923310789,0.3515923455547478,0.6561209993607429,-0.20101010976855774,-0.5601076639663766,-1.4294716859918053,0.8108826859948203,-1.134002123850734,-0.4274980724879269,0.11101698401404882,1.3615958927095713,0.8939906762605774,-0.5601076639663766,-0.18509422483019053,0.8108826859948203,-0.9376441237503343,-0.26501721992446775,-0.8501127548246629,2.5161229900221445,-1.2987125719306165,0.1415142579959687,0.6276405919776796,-0.16921237464871447,-0.21696018972606024,1.464604471440723,-0.012231339448816497,1.1646687956946997,0.9488974456277595,0.3367799639890156,2.6161644885369233,-0.5267307699032723,0.3367799639890156,0.5847183748800465,0.1718878508968803,2.1381080960394128,0.6986422043532152,-0.5601076639663766,0.3070674535939185,0.42522051928811844,0.9352077032562823,1.716292591643401,-0.763618598810603,-0.46042744525232726,-0.3458114723662479,2.254579138715145,1.2044591471962716,-0.18509422483019053,1.0575423433134081,-0.18509422483019053,-0.31338788818645713,2.844825243700939,0.8108826859948203,-1.0440899073566592,0.20213885674598203,-0.07462717308757696,-0.5601076639663766,3.5926238292445705,0.684494911792463,-0.5434002923310789,-0.6442189217896607,2.6821672119278386,0.09572162059983903,0.46905485711054756,0.21721872733739006,0.003286382816216437,-0.8501127548246629,0.41055230371744406,0.21721872733739006,0.20213885674598203,3.139895912874602,1.2044591471962716,0.684494911792463,0.49813702297415485 | 3,417 |
Intrinsic component of mitochondrial inner membrane | 20 | 34 | 2.576474 | 0.009981 | Q9Y2R0,Q16891,O14925,Q5XKP0,Q9H9P8,O60830,O95563,Q9H3K2,Q9HC21,Q6UXV4,Q99595,Q13505,O43819,Q9Y4W6,Q9NX63,Q6P4A7,O75880,P17152,Q8N8Q8,Q15070 | Localization | GO Cellular component | msigdb_gocc | 4,645,254,396,401,18,664,40,311,702,63,68,577,732,474,210,82,468,106,120 | 254,577,18,1703,82,664,468,2166,1501,1747,68,120,2027,645,817,1893,396,210,702,106,1721,1099,726,63,40,1451,401,311,1220,474,839,4,732,1108 | 1.464604471440723,0.7127631981492363,3.533699034108947,-0.15336440011844105,2.582956910707055,0.5990528096837081,0.9077544157121817,-0.3620767158842694,-0.04336396950002838,-0.16921237464871447,2.7367552921523206,2.1381080960394128,-0.2972292063859285,0.6276405919776796,0.42522051928811844,-0.23294462613289643,1.0575423433134081,1.6666027871242328,0.5559678555775356,2.254579138715145,-0.15336440011844105,0.20213885674598203,0.5271077117058275,2.844825243700939,3.0983999731344345,-0.012231339448816497,1.0575423433134081,1.2965110453880544,0.1262811501052972,0.9077544157121817,0.41055230371744406,4.205184051711286,0.5271077117058275,0.20213885674598203 | 3,417 |
Endoplasmic reticulum to golgi vesicle mediated transport | 22 | 78 | 2.549662 | 0.010783 | P51572,O43731,Q9P2W9,Q8NHH9,Q96PC5,Q9H0U4,P24390,Q6NUQ1,Q15363,O95070,Q969X5,Q9UHQ4,Q9Y282,Q08379,O14653,Q96JB2,Q9HD47,P61019,Q96RQ1,Q969M3,O95249,Q9Y3A6 | Processes and pathways | GO Biological process | msigdb_gobp | 256,132,7,270,15,406,41,430,49,308,188,327,70,340,464,354,229,486,362,376,123,384 | 1698,1223,464,1109,716,1989,1945,132,2406,1333,982,1671,308,123,2796,2158,3388,1134,41,1740,2169,641,494,256,737,3071,2755,2725,2315,486,1532,340,1412,1280,2541,2617,49,2252,1814,1416,2700,1419,2029,430,2032,1097,270,1781,1859,1422,376,188,354,15,362,806,555,406,2457,1759,1981,1864,229,598,940,7,2681,941,327,826,70,2234,810,384,1006,2343,2044,1081 | -0.15336440011844105,0.11101698401404882,0.9077544157121817,0.18702860941006846,0.5271077117058275,-0.28110570611391306,-0.26501721992446775,2.0555410573517667,-0.4769474308147848,0.04964694067544423,0.26227740933927773,-0.13755014327896972,1.2965110453880544,2.1146058237037426,-0.6951521821407869,-0.3620767158842694,-2.2474878163022267,0.1718878508968803,3.0879925141608315,-0.16921237464871447,-0.3620767158842694,0.6276405919776796,0.8525498970089892,1.464604471440723,0.5126362434312117,-0.9025053658548252,-0.6611574063587524,-0.6442189217896607,-0.4274980724879269,0.8663885158422502,-0.058979174610651705,1.2308721605709914,0.003286382816216437,0.0803949197759099,-0.5434002923310789,-0.5768530736707557,2.951456094882685,-0.3947149681833086,-0.20101010976855774,0.003286382816216437,-0.6273194417875337,0.003286382816216437,-0.2972292063859285,0.9898202205128834,-0.2972292063859285,0.20213885674598203,1.4261368498464053,-0.18509422483019053,-0.21696018972606024,0.003286382816216437,1.1112924650776037,1.753353058227572,1.1779551385349927,3.6414044791526283,1.151359444691466,0.43986026964991953,0.7689863138513828,1.0440457330659343,-0.4935045244272046,-0.16921237464871447,-0.26501721992446775,-0.21696018972606024,1.5788745256641128,0.6986422043532152,0.32193837550732557,4.021520229759403,-0.6104587700422,0.32193837550732557,1.2703225540070913,0.42522051928811844,2.7367552921523206,-0.3783778232336641,0.43986026964991953,1.0844644864570787,0.26227740933927773,-0.4274980724879269,-0.2972292063859285,0.21721872733739006 | 3,417 |
mitochondrial carrier protein | 6 | 8 | 2.537861 | 0.011153 | Q70HW3,Q6NUK1,Q9HC21,Q9BSK2,Q6KCM7,Q9NZJ7 | Functions | Panther Protein class | panther_protein_class | 133,199,311,24,281,343 | 1747,281,199,133,24,311,343,388 | -0.16921237464871447,1.4003850963299123,1.716292591643401,2.0436746509844026,3.374446699230225,1.2965110453880544,1.2308721605709914,1.0710152307117244 | 3,417 |
Lytic vacuole organization | 10 | 26 | 2.532344 | 0.01133 | Q14108,Q9HC07,P50897,P04062,Q8N511,Q96ED9,P54802,P10253,P11117,O75503 | Processes and pathways | GO Biological process | msigdb_gobp | 32,34,1,160,101,103,77,83,151,155 | 3006,164,155,364,160,1490,83,151,720,1,1310,77,1460,774,32,677,1096,101,2333,103,1787,34,3143,1696,1580,1667 | -0.8501127548246629,1.8513288969813924,1.8998599645471619,1.1380269980204456,1.8877553948021577,-0.04336396950002838,2.582956910707055,1.9240130911061084,0.5271077117058275,4.205184051711286,0.06503674048205203,2.6382261887100418,-0.027781407508477674,0.46905485711054756,3.22225286575062,0.5847183748800465,0.20213885674598203,2.369356778832258,-0.4274980724879269,2.3121762578160885,-0.18509422483019053,3.181179420737425,-0.9906722647822158,-0.13755014327896972,-0.07462717308757696,-0.12176944730407814 | 3,417 |
EF-hand domain pair [IPR011992] | 12 | 52 | 2.522131 | 0.011665 | O95302,Q9BRK5,O75071,Q9Y680,Q6NUK1,O95202,Q9NWM8,P41208,O43852,P80303,Q02818,Q14257 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 129,130,67,99,199,170,271,235,267,17,218,219 | 904,267,67,1333,873,170,129,3085,1803,735,3365,1737,3355,1804,1496,1361,235,2245,605,960,855,2660,17,218,3164,857,219,2975,1319,2506,281,199,2842,2393,2135,452,1349,1242,961,647,1021,130,964,895,744,271,977,941,787,759,514,99 | 0.3367799639890156,1.4261368498464053,2.7693299190267147,0.04964694067544423,0.3663756458799081,1.8391489210251506,2.0673895675906206,-0.920053561687098,-0.20101010976855774,0.5126362434312117,-1.8366943974697396,-0.16921237464871447,-1.6788137614948677,-0.20101010976855774,-0.04336396950002838,0.034225377321387807,1.5536262730798323,-0.3947149681833086,0.684494911792463,0.29216707088500893,0.3811299898070121,-0.6104587700422,3.5828325800136342,1.629126121507551,-1.0262403613136382,0.3811299898070121,1.629126121507551,-0.8153921382152115,0.06503674048205203,-0.5267307699032723,1.4003850963299123,1.716292591643401,-0.7122088737255577,-0.46042744525232726,-0.3458114723662479,0.9488974456277595,0.04964694067544423,0.11101698401404882,0.29216707088500893,0.6276405919776796,0.24728787146509176,2.0673895675906206,0.29216707088500893,0.3515923455547478,0.5126362434312117,1.4261368498464053,0.27723709916112255,0.32193837550732557,0.46905485711054756,0.49813702297415485,0.8247970828574156,2.403467854798666 | 3,417 |
Endopeptidase activity | 22 | 68 | 2.516723 | 0.011845 | Q6NTF9,P53634,P07711,P28074,Q9NZ08,O14773,Q9BXS4,Q96TA2,Q4J6C6,P07858,Q5JRX3,Q96K76,P67812,P20618,P22695,P49721,P42892,P28072,Q92542,Q99538,Q93009,O75844 | Functions | GO Molecular function | msigdb_gomf | 258,395,140,409,158,164,431,437,451,71,458,203,75,74,206,217,90,346,223,360,236,122 | 164,1701,2086,122,3085,140,71,2691,2470,3355,74,206,2694,1010,346,409,2930,2856,1993,1768,3215,90,2437,2535,1039,217,1211,1277,395,3267,1531,1618,880,75,1387,676,1464,1646,2882,3139,1470,451,458,1045,258,1971,3091,1327,223,1543,671,2332,236,203,459,437,552,360,526,3175,431,837,158,2560,943,1248,2892,732 | 1.8513288969813924,-0.15336440011844105,-0.32958192020084226,2.1146058237037426,-0.920053561687098,1.98407208930781,2.6931147394707224,-0.6273194417875337,-0.5100989092650228,-1.6788137614948677,2.6492341726847237,1.6790550002814526,-0.6273194417875337,0.24728787146509176,1.2044591471962716,1.0305253082286936,-0.7808357432419631,-0.729305370654242,-0.28110570611391306,-0.18509422483019053,-1.1159302783535316,2.5273010692633533,-0.4935045244272046,-0.5434002923310789,0.23226835470484916,1.629126121507551,0.1262811501052972,0.0803949197759099,1.0575423433134081,-1.2250442111451176,-0.058979174610651705,-0.10602215649073785,0.3663756458799081,2.6492341726847237,0.018771906383900746,0.5847183748800465,-0.027781407508477674,-0.12176944730407814,-0.7464418770883892,-0.9906722647822158,-0.027781407508477674,0.9488974456277595,0.9352077032562823,0.23226835470484916,1.464604471440723,-0.26501721992446775,-0.920053561687098,0.06503674048205203,1.6040409488013108,-0.058979174610651705,0.5990528096837081,-0.4274980724879269,1.5536262730798323,1.6914873258283896,0.9352077032562823,0.9762036088666618,0.7689863138513828,1.1646687956946997,0.8108826859948203,-1.0440899073566592,0.9898202205128834,0.41055230371744406,1.8998599645471619,-0.5434002923310789,0.32193837550732557,0.11101698401404882,-0.7464418770883892,0.5271077117058275 | 3,417 |
Respiratory distress | 13 | 57 | 2.500794 | 0.012392 | P04062,Q9UHX1,Q969X5,P00846,P10253,P53701,P07602,O95831,P03886,P04350,Q13510,Q9NZJ7,Q9Y619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 160,35,188,5,83,404,23,54,25,250,61,343,159 | 577,2114,3113,2046,1669,2373,1735,54,5,25,160,250,23,1736,83,764,2989,2243,1992,3158,919,1231,1177,3119,3385,815,1365,905,558,1088,2351,404,2125,1386,3072,1747,767,429,2994,61,2442,3034,1416,2027,1562,2332,188,2333,2916,703,2068,2398,2983,343,35,2715,159 | 0.7127631981492363,-0.3458114723662479,-0.9552772768646035,-0.31338788818645713,-0.13755014327896972,-0.46042744525232726,-0.16921237464871447,2.8876479191575553,4.150512780930534,3.334140571921885,1.8877553948021577,1.4901437800337045,3.3844919984080626,-0.16921237464871447,2.582956910707055,0.4836099334246191,-0.8327318119520807,-0.3947149681833086,-0.28110570611391306,-1.0262403613136382,0.32193837550732557,0.11101698401404882,0.1415142579959687,-0.9552772768646035,-2.1425284599508747,0.42522051928811844,0.034225377321387807,0.3367799639890156,0.7549694526938922,0.20213885674598203,-0.4439443859497023,1.0440457330659343,-0.3458114723662479,0.018771906383900746,-0.9025053658548252,-0.16921237464871447,0.4836099334246191,0.9898202205128834,-0.8327318119520807,2.855552391486076,-0.4935045244272046,-0.8675351827166916,0.003286382816216437,-0.2972292063859285,-0.07462717308757696,-0.4274980724879269,1.753353058227572,-0.4274980724879269,-0.763618598810603,0.5559678555775356,-0.31338788818645713,-0.46042744525232726,-0.8153921382152115,1.2308721605709914,3.1708783290039375,-0.6273194417875337,1.8998599645471619 | 3,417 |
Membrane lipid metabolic process | 19 | 40 | 2.493354 | 0.012654 | P50897,Q6Y1H2,Q16880,P06865,Q9NRA0,P07602,O95470,Q8NCC3,P04062,Q99805,Q96G23,Q13510,O15269,Q9NZJ7,P17900,Q06136,P06280,Q16739,P16278 | Processes and pathways | GO Biological process | msigdb_gobp | 1,522,145,144,407,23,153,285,160,553,56,61,446,343,221,484,232,115,373 | 3368,446,1833,2046,153,160,572,232,144,23,1490,373,221,1557,1637,667,1708,1,484,908,1137,61,115,145,817,522,1754,285,1543,997,56,2292,712,553,407,1694,1826,343,3375,940 | -1.8968144751645826,0.9488974456277595,-0.21696018972606024,-0.31338788818645713,1.911945842266695,1.8877553948021577,0.7268580000891784,1.5536262730798323,1.9720970491130785,3.3844919984080626,-0.04336396950002838,1.1112924650776037,1.6040409488013108,-0.07462717308757696,-0.12176944730407814,0.5990528096837081,-0.15336440011844105,4.205184051711286,0.8802020758474672,0.3367799639890156,0.1718878508968803,2.855552391486076,2.16154041194842,1.9720970491130785,0.42522051928811844,0.8108826859948203,-0.16921237464871447,1.3745472757064856,-0.058979174610651705,0.26227740933927773,2.8876479191575553,-0.41108832580523696,0.5415515439526422,0.7689863138513828,1.0440457330659343,-0.13755014327896972,-0.20101010976855774,1.2308721605709914,-1.957448063960899,0.32193837550732557 | 3,417 |
Arthritis | 14 | 45 | 2.490947 | 0.01274 | Q14108,P10321,P04062,P21964,P35670,P51798,Q8WVQ1,P06280,P14174,Q96HY6,P02545,O75844,Q13510,Q9NZ08 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,322,160,66,420,358,424,232,43,104,393,122,61,158 | 1029,2820,958,122,2266,749,393,160,232,2241,322,3046,43,66,3158,1010,420,1709,1458,358,2755,2725,2123,1772,2582,2094,642,61,32,470,2218,2325,2136,1421,424,1656,2450,104,1193,1661,1825,158,1483,2402,1331 | 0.23226835470484916,-0.7122088737255577,0.29216707088500893,2.1146058237037426,-0.41108832580523696,0.49813702297415485,1.0575423433134081,1.8877553948021577,1.5536262730798323,-0.3947149681833086,1.2703225540070913,-0.8849993132602134,3.0462276398142834,2.790972813120915,-1.0262403613136382,0.24728787146509176,1.003412645073793,-0.15336440011844105,-0.027781407508477674,1.1646687956946997,-0.6611574063587524,-0.6442189217896607,-0.3458114723662479,-0.18509422483019053,-0.5601076639663766,-0.32958192020084226,0.6276405919776796,2.855552391486076,3.22225286575062,0.9077544157121817,-0.3783778232336641,-0.4274980724879269,-0.3458114723662479,0.003286382816216437,1.003412645073793,-0.12176944730407814,-0.4935045244272046,2.3006903741988816,0.1415142579959687,-0.12176944730407814,-0.20101010976855774,1.8998599645471619,-0.027781407508477674,-0.46042744525232726,0.06503674048205203 | 3,417 |
Corneal opacity | 20 | 57 | 2.487959 | 0.012848 | O43683,P02545,O96028,P53701,P04062,P51648,O95202,Q13510,Q8NFV4,Q9NVI7,Q6NUK1,P40855,P10619,Q96J42,O43505,P06280,P16278,P08236,O75844,Q9H9S5 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 260,393,272,404,160,36,170,61,191,196,199,336,85,228,357,232,373,243,122,381 | 637,3084,1634,357,260,2946,1379,3246,1035,717,122,626,3157,170,2824,272,393,160,572,232,243,2528,85,373,2349,1272,3389,2309,420,336,1956,947,36,1924,404,2352,2477,2094,3164,484,2415,61,724,1157,2389,2836,199,1073,191,228,3218,381,196,3392,599,2458,760 | 0.6276405919776796,-0.920053561687098,-0.12176944730407814,1.1646687956946997,1.4518031621126333,-0.7980935194597194,0.018771906383900746,-1.1884897999995363,0.23226835470484916,0.5271077117058275,2.1146058237037426,0.6418941622736091,-1.0262403613136382,1.8391489210251506,-0.7122088737255577,1.4132716921952186,1.0575423433134081,1.8877553948021577,0.7268580000891784,1.5536262730798323,1.5028819314367052,-0.5434002923310789,2.5607412932011338,1.1112924650776037,-0.4439443859497023,0.0803949197759099,-2.2474878163022267,-0.4274980724879269,1.003412645073793,1.24404475743253,-0.26501721992446775,0.3070674535939185,3.1502366120869385,-0.2489635815987443,1.0440457330659343,-0.4439443859497023,-0.5100989092650228,-0.32958192020084226,-1.0262403613136382,0.8802020758474672,-0.4769474308147848,2.855552391486076,0.5271077117058275,0.15671644585303687,-0.46042744525232726,-0.7122088737255577,1.716292591643401,0.21721872733739006,1.7410191359493292,1.5788745256641128,-1.1159302783535316,1.097890201205585,1.7286656697551432,-2.397114900684787,0.6986422043532152,-0.4935045244272046,0.49813702297415485 | 3,417 |
Membrane lipid catabolic process | 6 | 11 | 2.472175 | 0.013429 | P04062,P50897,P06865,P17900,O95470,Q13510 | Processes and pathways | GO Biological process | msigdb_gobp | 160,1,144,221,153,61 | 153,160,572,232,144,1490,221,1,61,712,1694 | 1.911945842266695,1.8877553948021577,0.7268580000891784,1.5536262730798323,1.9720970491130785,-0.04336396950002838,1.6040409488013108,4.205184051711286,2.855552391486076,0.5415515439526422,-0.13755014327896972 | 3,417 |
Paralysis | 13 | 52 | 2.471724 | 0.013446 | P04062,Q96PY6,P51798,Q92804,P35637,P50402,P21912,P10253,Q68CQ7,Q9HC21,Q8TB36,P17900,Q15165 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 160,400,358,266,197,268,378,83,117,311,348,221,29 | 1671,1084,2796,2346,393,160,1764,2203,3066,2267,1058,2528,83,520,221,2657,1113,2118,378,2436,197,1258,1993,2090,3276,2633,923,1501,268,1276,358,2122,2352,2315,3337,699,1680,951,1181,29,776,117,348,1016,266,400,1101,311,1548,1266,1580,2524 | -0.13755014327896972,0.20213885674598203,-0.6951521821407869,-0.4439443859497023,1.0575423433134081,1.8877553948021577,-0.18509422483019053,-0.3783778232336641,-0.9025053658548252,-0.41108832580523696,0.21721872733739006,-0.5434002923310789,2.582956910707055,0.8108826859948203,1.6040409488013108,-0.6104587700422,0.18702860941006846,-0.3458114723662479,1.097890201205585,-0.4935045244272046,1.716292591643401,0.09572162059983903,-0.28110570611391306,-0.32958192020084226,-1.2433909693380374,-0.5936367117645664,0.32193837550732557,-0.04336396950002838,1.4261368498464053,0.0803949197759099,1.1646687956946997,-0.3458114723662479,-0.4439443859497023,-0.4274980724879269,-1.4862472345846647,0.5559678555775356,-0.13755014327896972,0.3070674535939185,0.1415142579959687,3.2936329120887344,0.46905485711054756,2.1498329700173007,1.2044591471962716,0.24728787146509176,1.43898064729436,1.0575423433134081,0.20213885674598203,1.2965110453880544,-0.058979174610651705,0.09572162059983903,-0.07462717308757696,-0.5267307699032723 | 3,417 |
Abnormal vascular physiology | 16 | 56 | 2.462307 | 0.013805 | Q14108,Q8IZA0,P04062,P51798,Q6NUK1,P06280,Q9NWM8,P02545,Q71SY5,Q14739,P00403,P05067,P03886,O75844,Q9NZ08,Q8NFV4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,347,160,358,199,232,271,393,48,470,175,241,25,122,158,191 | 2927,958,1401,2606,122,1919,1133,175,749,393,25,160,2526,241,232,764,2162,603,3213,2118,919,477,3049,1879,1273,2309,878,1709,1882,358,558,1772,2477,1959,3015,32,3231,470,1157,3271,953,199,48,347,1421,191,1858,2333,2297,271,158,3392,2458,1665,1331,760 | -0.7808357432419631,0.29216707088500893,0.003286382816216437,-0.5768530736707557,2.1146058237037426,-0.2489635815987443,0.1718878508968803,1.8024946555524302,0.49813702297415485,1.0575423433134081,3.334140571921885,1.8877553948021577,-0.5434002923310789,1.5155991816321197,1.5536262730798323,0.4836099334246191,-0.3620767158842694,0.684494911792463,-1.1159302783535316,-0.3458114723662479,0.32193837550732557,0.8939906762605774,-0.8849993132602134,-0.23294462613289643,0.0803949197759099,-0.4274980724879269,0.3663756458799081,-0.15336440011844105,-0.23294462613289643,1.1646687956946997,0.7549694526938922,-0.18509422483019053,-0.5100989092650228,-0.26501721992446775,-0.8501127548246629,3.22225286575062,-1.1521191599990652,0.9077544157121817,0.15671644585303687,-1.2250442111451176,0.3070674535939185,1.716292591643401,2.9726132439273627,1.2044591471962716,0.003286382816216437,1.7410191359493292,-0.21696018972606024,-0.4274980724879269,-0.41108832580523696,1.4261368498464053,1.8998599645471619,-2.397114900684787,-0.4935045244272046,-0.12176944730407814,0.06503674048205203,0.49813702297415485 | 3,417 |
Cherry red spot of the macula | 6 | 9 | 2.435189 | 0.014884 | P06865,Q13510,P10619,P07602,P17900,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 144,61,85,23,221,343 | 144,23,1490,85,2692,373,221,61,343 | 1.9720970491130785,3.3844919984080626,-0.04336396950002838,2.5607412932011338,-0.6273194417875337,1.1112924650776037,1.6040409488013108,2.855552391486076,1.2308721605709914 | 3,417 |
Cytochrome complex assembly | 6 | 13 | 2.420285 | 0.015508 | Q9Y2R0,Q8N8Q8,O75880,Q69YU5,Q9BSK2,Q15070 | Processes and pathways | GO Biological process | msigdb_gobp | 4,106,82,21,24,120 | 577,82,404,120,1649,21,147,496,106,1758,24,1428,4 | 0.7127631981492363,2.582956910707055,1.0440457330659343,2.1381080960394128,-0.12176944730407814,3.444504034604731,1.9720970491130785,0.8525498970089892,2.254579138715145,-0.16921237464871447,3.374446699230225,0.003286382816216437,4.205184051711286 | 3,417 |
Sphingolipid metabolism | 8 | 11 | 2.410289 | 0.01594 | P04062,O15269,Q16880,Q16739,P07602,P17900,O95470,Q13510 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 160,446,145,115,23,221,153,61 | 446,1833,153,160,23,221,484,61,115,145,1826 | 0.9488974456277595,-0.21696018972606024,1.911945842266695,1.8877553948021577,3.3844919984080626,1.6040409488013108,0.8802020758474672,2.855552391486076,2.16154041194842,1.9720970491130785,-0.20101010976855774 | 3,417 |
Endoplasmic reticulum tubular network organization | 6 | 11 | 2.405042 | 0.016171 | Q9NQC3,O95197,Q8NHH9,Q9H6H4,Q15041,P61026 | Processes and pathways | GO Biological process | msigdb_gobp | 39,42,270,304,114,150 | 42,337,150,114,2667,2029,270,1372,304,1577,39 | 3.0462276398142834,1.24404475743253,1.9360617738820296,2.16154041194842,-0.6104587700422,-0.2972292063859285,1.4261368498464053,0.034225377321387807,1.3226108940757686,-0.07462717308757696,3.1087940046652425 | 3,417 |
Rigidity | 14 | 55 | 2.368914 | 0.01784 | Q9Y263,P04062,O14936,P37198,P00846,Q96CU9,O75787,P12235,Q9H6K4,Q15392,P16278,P07602,P04350,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 193,160,419,530,5,163,364,519,20,245,373,23,250,343 | 1030,419,693,2372,364,1800,3031,5,160,250,23,519,373,2268,2780,2532,2165,530,2611,3180,3104,1770,2207,1924,1772,1926,2832,2584,583,1411,2173,1316,1181,245,2177,2283,1471,882,2740,163,1572,1974,1787,2139,2594,1021,2071,20,343,942,1580,193,1080,1331,732 | 0.23226835470484916,1.003412645073793,0.5559678555775356,-0.46042744525232726,1.1380269980204456,-0.20101010976855774,-0.8675351827166916,4.150512780930534,1.8877553948021577,1.4901437800337045,3.3844919984080626,0.8108826859948203,1.1112924650776037,-0.41108832580523696,-0.6781350933421636,-0.5434002923310789,-0.3620767158842694,0.7969428272052425,-0.5768530736707557,-1.0619834328894011,-0.9376441237503343,-0.18509422483019053,-0.3783778232336641,-0.2489635815987443,-0.18509422483019053,-0.2489635815987443,-0.7122088737255577,-0.5601076639663766,0.7127631981492363,0.003286382816216437,-0.3620767158842694,0.06503674048205203,0.1415142579959687,1.5028819314367052,-0.3620767158842694,-0.41108832580523696,-0.027781407508477674,0.3663756458799081,-0.6442189217896607,1.8756320695553226,-0.07462717308757696,-0.26501721992446775,-0.18509422483019053,-0.3458114723662479,-0.5601076639663766,0.24728787146509176,-0.31338788818645713,3.4544630581633307,1.2308721605709914,0.32193837550732557,-0.07462717308757696,1.7410191359493292,0.21721872733739006,0.06503674048205203,0.5271077117058275 | 3,417 |
Glycosphingolipid metabolism | 10 | 17 | 2.35931 | 0.018309 | P04062,P06280,Q16880,P06865,Q16739,P10619,Q13510,P07602,P17900,Q9NZJ7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 160,232,145,144,115,85,61,23,221,343 | 1697,693,160,232,144,23,1490,85,373,221,61,115,145,2673,2844,1694,343 | -0.15336440011844105,0.5559678555775356,1.8877553948021577,1.5536262730798323,1.9720970491130785,3.3844919984080626,-0.04336396950002838,2.5607412932011338,1.1112924650776037,1.6040409488013108,2.855552391486076,2.16154041194842,1.9720970491130785,-0.6104587700422,-0.7122088737255577,-0.13755014327896972,1.2308721605709914 | 3,417 |
Intrinsic component of plasma membrane | 43 | 90 | 2.354614 | 0.018542 | P51572,P48960,Q9UJS0,Q99797,P27105,O60637,Q8NBJ4,P12235,P05026,O15031,O15118,O00264,O00400,Q9UIQ6,P35670,Q99805,Q9BTU6,P11279,Q8WTV0,P04439,Q15043,O96005,Q02978,P10321,P16615,P05023,P17152,Q08722,O15498,P20645,Q92542,P35613,P19022,Q8NAN2,Q99808,P01889,Q9NR28,P05067,P53985,P51790,Q13641,O00560,P30825 | Localization | GO Cellular component | msigdb_gocc | 256,386,787,526,137,10,658,519,518,516,152,26,27,286,420,553,554,46,177,434,700,313,699,322,698,579,468,344,716,220,223,352,485,365,624,749,112,241,500,629,119,762,126 | 1697,26,27,762,1030,3030,516,1634,152,3368,716,1610,10,842,313,749,1673,434,579,518,241,889,1253,1435,3179,2161,1803,322,46,890,519,698,468,485,1949,220,919,1705,137,1456,1950,126,1675,352,420,1258,3125,386,256,629,500,2055,1259,894,1117,1387,1747,699,344,1412,1929,119,2059,1414,700,2130,1468,1892,778,2102,1369,365,658,1446,1687,177,223,526,553,624,554,3411,1163,2111,112,1911,286,787,901,3376 | -0.15336440011844105,3.3240326367824573,3.3240326367824573,0.4836099334246191,0.23226835470484916,-0.8675351827166916,0.8108826859948203,-0.12176944730407814,1.911945842266695,-1.8968144751645826,0.5271077117058275,-0.10602215649073785,3.7380999268990847,0.3958555013531686,1.2834279212620188,0.49813702297415485,-0.13755014327896972,0.9762036088666618,0.7127631981492363,0.8108826859948203,1.5155991816321197,0.3515923455547478,0.09572162059983903,-0.012231339448816497,-1.0619834328894011,-0.3620767158842694,-0.20101010976855774,1.2703225540070913,2.9831709549906043,0.3515923455547478,0.8108826859948203,0.5559678555775356,0.9077544157121817,0.8663885158422502,-0.26501721992446775,1.616593655517,0.32193837550732557,-0.15336440011844105,2.007967460097441,-0.027781407508477674,-0.26501721992446775,2.0910331355693024,-0.13755014327896972,1.1779551385349927,1.003412645073793,0.09572162059983903,-0.972953247696988,1.0710152307117244,1.464604471440723,0.6418941622736091,0.8386861195013237,-0.31338788818645713,0.09572162059983903,0.3515923455547478,0.18702860941006846,0.018771906383900746,-0.16921237464871447,0.5559678555775356,1.2176769854892084,0.003286382816216437,-0.2489635815987443,2.1381080960394128,-0.31338788818645713,0.003286382816216437,0.5559678555775356,-0.3458114723662479,-0.027781407508477674,-0.23294462613289643,0.46905485711054756,-0.32958192020084226,0.034225377321387807,1.1380269980204456,0.6133601781301887,-0.012231339448816497,-0.13755014327896972,1.8024946555524302,1.6040409488013108,0.8108826859948203,0.7689863138513828,0.6561209993607429,0.7689863138513828,-5.949729985797729,0.15671644585303687,-0.32958192020084226,2.1732304785344865,-0.23294462613289643,1.3745472757064856,0.46905485711054756,0.3515923455547478,-1.957448063960899 | 3,417 |
Optic disc pallor | 21 | 51 | 2.348003 | 0.018874 | Q6P4Q7,Q03426,P00846,Q9H061,O00754,Q9H6K4,Q96S66,P03886,Q10713,Q8WWY3,O60313,O14936,Q96CU9,O43676,Q9H0B6,P04439,Q9NPL8,O95831,Q96L58,P51798,Q9Y6M9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 508,642,5,8,637,20,405,25,676,547,542,419,163,37,689,434,179,54,703,358,515 | 3377,1832,637,419,1834,37,2463,542,2200,1669,763,2086,1360,2986,1084,54,1133,5,25,434,2692,2657,3311,1920,3339,3326,358,3337,642,676,1649,508,2103,934,547,1784,163,703,1100,405,2398,1861,1102,8,689,20,179,1518,839,732,515 | -1.9777750442589752,-0.21696018972606024,0.6276405919776796,1.003412645073793,-0.21696018972606024,3.139895912874602,-0.5100989092650228,0.7829774041493419,-0.3783778232336641,-0.13755014327896972,0.4836099334246191,-0.32958192020084226,0.034225377321387807,-0.8327318119520807,0.20213885674598203,2.8876479191575553,0.1718878508968803,4.150512780930534,3.334140571921885,0.9762036088666618,-0.6273194417875337,-0.6104587700422,-1.3918689663666952,-0.2489635815987443,-1.543475472466397,-1.4483470542519512,1.1646687956946997,-1.4862472345846647,0.6276405919776796,0.5847183748800465,-0.12176944730407814,0.8247970828574156,-0.32958192020084226,0.32193837550732557,0.7829774041493419,-0.18509422483019053,1.8756320695553226,0.5559678555775356,0.20213885674598203,1.0440457330659343,-0.46042744525232726,-0.21696018972606024,0.20213885674598203,3.871581837843975,0.5703567612440847,3.4544630581633307,1.7902382361488205,-0.04336396950002838,0.41055230371744406,0.5271077117058275,0.8247970828574156 | 3,417 |
Molecular transducer activity | 16 | 40 | 2.344207 | 0.019068 | O15173,Q14108,P48960,Q08722,P30536,O75787,Q8WTV0,O15031,Q9Y6I9,Q5KU26,Q9BUN8,Q9NRA0,O15118,Q6RW13,P20645,Q15629 | Functions | GO Molecular function | msigdb_gomf | 0,32,386,344,521,364,177,516,339,242,84,407,152,534,220,30 | 3030,516,152,0,364,1253,3179,890,719,220,920,1950,521,2051,2167,386,1709,2412,344,1929,32,1468,30,1892,802,242,2445,534,177,1820,1354,561,1630,84,407,1911,2339,2745,1246,339 | -0.8675351827166916,0.8108826859948203,1.911945842266695,4.205184051711286,1.1380269980204456,0.09572162059983903,-1.0619834328894011,0.3515923455547478,0.5271077117058275,1.616593655517,0.32193837550732557,-0.26501721992446775,0.8108826859948203,-0.31338788818645713,-0.3620767158842694,1.0710152307117244,-0.15336440011844105,-0.4769474308147848,1.2176769854892084,-0.2489635815987443,3.22225286575062,-0.027781407508477674,3.2936329120887344,-0.23294462613289643,0.43986026964991953,1.5155991816321197,-0.4935045244272046,0.7969428272052425,1.8024946555524302,-0.20101010976855774,0.04964694067544423,0.7549694526938922,-0.10602215649073785,2.582956910707055,1.0440457330659343,-0.23294462613289643,-0.4274980724879269,-0.6442189217896607,0.11101698401404882,1.24404475743253 | 3,417 |
Mental deterioration | 27 | 103 | 2.338155 | 0.019379 | Q9BQE5,P50897,P00846,Q5XKP0,P06865,Q9Y487,P07602,O15118,O95470,P03886,O75503,Q14108,P04062,P00403,Q9NPL8,Q13510,P21964,P35637,P54802,Q9NZJ7,P17900,Q9NQZ5,P21912,P05067,P16278,P04350,P61916 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 3,1,5,396,144,149,23,152,153,25,155,32,160,175,179,61,66,197,77,343,221,231,378,241,373,250,257 | 1832,1030,1943,152,693,577,578,542,2085,2372,1669,155,1670,1084,1800,153,1037,175,5,25,160,2653,250,241,144,23,1490,2267,3115,1058,3116,1254,373,2268,221,1113,378,66,457,2610,667,2436,1880,197,420,1063,2611,2952,3180,923,3104,1,3277,2207,77,2352,2315,257,1926,2832,2356,1041,2584,583,1411,2173,676,1316,1680,951,61,32,1181,2731,1626,396,3366,2447,2283,1471,1392,1263,2740,1974,1787,1193,2139,2594,3273,3,2398,2071,179,231,2559,343,758,3201,1266,942,1580,1080,149 | -0.21696018972606024,0.23226835470484916,-0.26501721992446775,1.911945842266695,0.5559678555775356,0.7127631981492363,0.7127631981492363,0.7829774041493419,-0.32958192020084226,-0.46042744525232726,-0.13755014327896972,1.8998599645471619,-0.13755014327896972,0.20213885674598203,-0.20101010976855774,1.911945842266695,0.23226835470484916,1.8024946555524302,4.150512780930534,3.334140571921885,1.8877553948021577,-0.6104587700422,1.4901437800337045,1.5155991816321197,1.9720970491130785,3.3844919984080626,-0.04336396950002838,-0.41108832580523696,-0.9552772768646035,0.21721872733739006,-0.9552772768646035,0.09572162059983903,1.1112924650776037,-0.41108832580523696,1.6040409488013108,0.18702860941006846,1.097890201205585,2.790972813120915,0.9352077032562823,-0.5768530736707557,0.5990528096837081,-0.4935045244272046,-0.23294462613289643,1.716292591643401,1.003412645073793,0.21721872733739006,-0.5768530736707557,-0.7980935194597194,-1.0619834328894011,0.32193837550732557,-0.9376441237503343,4.205184051711286,-1.2433909693380374,-0.3783778232336641,2.6382261887100418,-0.4439443859497023,-0.4274980724879269,1.464604471440723,-0.2489635815987443,-0.7122088737255577,-0.4439443859497023,0.23226835470484916,-0.5601076639663766,0.7127631981492363,0.003286382816216437,-0.3620767158842694,0.5847183748800465,0.06503674048205203,-0.13755014327896972,0.3070674535939185,2.855552391486076,3.22225286575062,0.1415142579959687,-0.6442189217896607,-0.10602215649073785,1.0575423433134081,-1.8366943974697396,-0.4935045244272046,-0.41108832580523696,-0.027781407508477674,0.018771906383900746,0.09572162059983903,-0.6442189217896607,-0.26501721992446775,-0.18509422483019053,0.1415142579959687,-0.3458114723662479,-0.5601076639663766,-1.2250442111451176,4.205184051711286,-0.46042744525232726,-0.31338788818645713,1.7902382361488205,1.5662606644900365,-0.5434002923310789,1.2308721605709914,0.49813702297415485,-1.0799211761036647,0.09572162059983903,0.32193837550732557,-0.07462717308757696,0.21721872733739006,1.9480919530847027 | 3,417 |
Bulbar signs | 7 | 13 | 2.338045 | 0.019385 | Q9Y263,P04062,P00846,P35637,P07602,P03886,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 193,160,5,197,23,25,343 | 693,5,25,160,371,23,197,923,700,1422,1630,343,193 | 0.5559678555775356,4.150512780930534,3.334140571921885,1.8877553948021577,1.1112924650776037,3.3844919984080626,1.716292591643401,0.32193837550732557,0.5559678555775356,0.003286382816216437,-0.10602215649073785,1.2308721605709914,1.7410191359493292 | 3,417 |
Golgi membrane | 56 | 154 | 2.337646 | 0.019406 | Q6NTF9,Q86Y82,P51572,O43731,Q9P2W9,Q8NBN3,Q8N4V1,Q96S66,P61026,Q9H0U4,Q7Z3C6,O00400,Q9H4A6,Q14108,O00461,Q9HC07,O43752,P35670,Q6UWU4,P24390,O95197,Q9BXS4,Q10469,Q15363,P04439,O15258,O95070,Q9Y3E0,Q969X5,Q6ZRP7,Q8NCH0,P10321,Q9Y282,Q8IV08,L0R6Q1,Q8TBA6,Q7LGA3,Q08379,Q16799,O14653,Q10472,O60499,Q9H7Z7,Q8IZA0,Q92896,P35613,O95721,Q96JB2,Q8TB61,O43505,P61019,P49755,Q16739,Q15392,O95249,Q9H9S5 | Localization | GO Cellular component | msigdb_gocc | 258,383,256,132,7,141,14,405,150,406,282,27,157,32,288,34,165,420,167,41,42,431,429,49,434,433,308,312,188,316,62,322,70,69,455,78,208,340,341,464,469,89,349,347,351,352,476,354,102,357,486,494,115,245,123,381 | 455,27,288,1223,2082,464,1109,433,1916,716,357,1945,132,2604,165,89,2406,982,308,42,123,476,749,434,1736,1172,322,890,892,1637,41,622,1740,352,420,2575,673,720,2169,2613,641,494,1529,256,629,1233,1340,3071,2755,1773,3205,2439,2383,1642,486,150,1460,1643,1462,1620,1532,1387,1408,800,973,3322,340,429,1072,469,2861,676,2781,1412,1280,1238,32,2060,507,2763,2130,49,245,2252,1416,1185,115,341,2700,258,534,167,316,208,282,2912,383,862,69,347,14,1779,819,141,62,1242,102,78,1858,1781,1859,2329,351,188,2511,354,703,405,867,555,3200,431,936,406,2457,2145,3004,157,349,2368,1980,381,34,1864,1548,870,1694,940,7,2681,1551,899,3080,1732,707,70,2234,2984,2891,2263,3028,1006,312,2044 | 0.9352077032562823,3.3240326367824573,1.3615958927095713,0.11101698401404882,-0.32958192020084226,0.9077544157121817,0.18702860941006846,0.9762036088666618,-0.2489635815987443,0.5271077117058275,1.1646687956946997,-0.26501721992446775,2.0555410573517667,-0.5768530736707557,1.8513288969813924,2.5273010692633533,-0.4769474308147848,0.26227740933927773,1.2965110453880544,3.0462276398142834,2.1146058237037426,0.8939906762605774,0.49813702297415485,0.9762036088666618,-0.16921237464871447,0.1415142579959687,1.2703225540070913,0.3515923455547478,0.3515923455547478,-0.12176944730407814,3.0879925141608315,0.6561209993607429,-0.16921237464871447,1.1779551385349927,1.003412645073793,-0.5601076639663766,0.5847183748800465,0.5271077117058275,-0.3620767158842694,-0.5768530736707557,0.6276405919776796,0.8525498970089892,-0.058979174610651705,1.464604471440723,0.6418941622736091,0.11101698401404882,0.04964694067544423,-0.9025053658548252,-0.6611574063587524,-0.18509422483019053,-1.0979033771886262,-0.4935045244272046,-0.46042744525232726,-0.12176944730407814,0.8663885158422502,1.9360617738820296,-0.027781407508477674,-0.12176944730407814,-0.027781407508477674,-0.10602215649073785,-0.058979174610651705,0.018771906383900746,0.003286382816216437,0.43986026964991953,0.27723709916112255,-1.4294716859918053,1.2308721605709914,0.9898202205128834,0.21721872733739006,0.9077544157121817,-0.729305370654242,0.5847183748800465,-0.6781350933421636,0.003286382816216437,0.0803949197759099,0.11101698401404882,3.22225286575062,-0.31338788818645713,0.8247970828574156,-0.6611574063587524,-0.3458114723662479,2.951456094882685,1.5028819314367052,-0.3947149681833086,0.003286382816216437,0.1415142579959687,2.16154041194842,1.2308721605709914,-0.6273194417875337,1.464604471440723,0.7969428272052425,1.8513288969813924,1.2834279212620188,1.6790550002814526,1.4003850963299123,-0.763618598810603,1.0844644864570787,0.3811299898070121,2.7367552921523206,1.2044591471962716,3.660835364784335,-0.18509422483019053,0.42522051928811844,1.98407208930781,2.855552391486076,0.11101698401404882,2.3465341395617054,2.6272029760773212,-0.21696018972606024,-0.18509422483019053,-0.21696018972606024,-0.4274980724879269,1.1912185602063996,1.753353058227572,-0.5267307699032723,1.1779551385349927,0.5559678555775356,1.0440457330659343,0.3811299898070121,0.7689863138513828,-1.0799211761036647,0.9898202205128834,0.32193837550732557,1.0440457330659343,-0.4935045244272046,-0.3458114723662479,-0.8327318119520807,1.8998599645471619,1.2044591471962716,-0.4439443859497023,-0.26501721992446775,1.097890201205585,3.181179420737425,-0.21696018972606024,-0.058979174610651705,0.3811299898070121,-0.13755014327896972,0.32193837550732557,4.021520229759403,-0.6104587700422,-0.058979174610651705,0.3515923455547478,-0.9025053658548252,-0.15336440011844105,0.5559678555775356,2.7367552921523206,-0.3783778232336641,-0.8153921382152115,-0.7464418770883892,-0.3947149681833086,-0.8501127548246629,0.26227740933927773,1.2965110453880544,-0.2972292063859285 | 3,417 |
Copi dependent golgi to er retrograde traffic | 14 | 55 | 2.322988 | 0.02018 | Q13885,O43731,Q9P2W9,P24390,Q9NSK0,Q9BVA1,Q6NUQ1,P49755,Q9BUF5,Q15363,Q12981,Q9H0U4,P04350,P68371 | Processes and pathways | Reactome Pathways | msigdb_reactome | 291,132,7,41,427,332,430,494,367,49,275,406,250,251 | 1299,1008,1223,1916,1989,132,982,1919,1837,250,1134,41,986,1740,1954,2169,494,1924,3071,2755,1997,1643,1532,251,766,2384,738,2358,275,775,291,2218,49,430,975,1779,819,1859,864,3347,3133,1328,367,332,555,3022,689,1355,406,427,7,2681,1006,965,2044 | 0.06503674048205203,0.24728787146509176,0.11101698401404882,-0.2489635815987443,-0.28110570611391306,2.0555410573517667,0.26227740933927773,-0.2489635815987443,-0.21696018972606024,1.4901437800337045,0.1718878508968803,3.0879925141608315,0.26227740933927773,-0.16921237464871447,-0.26501721992446775,-0.3620767158842694,0.8525498970089892,-0.2489635815987443,-0.9025053658548252,-0.6611574063587524,-0.28110570611391306,-0.12176944730407814,-0.058979174610651705,1.4901437800337045,0.4836099334246191,-0.46042744525232726,0.5126362434312117,-0.4439443859497023,1.4132716921952186,0.46905485711054756,1.3615958927095713,-0.3783778232336641,2.951456094882685,0.9898202205128834,0.27723709916112255,-0.18509422483019053,0.42522051928811844,-0.21696018972606024,0.3811299898070121,-1.5818830601858436,-0.972953247696988,0.06503674048205203,1.1380269980204456,1.2571948605736722,0.7689863138513828,-0.8501127548246629,0.5703567612440847,0.04964694067544423,1.0440457330659343,1.003412645073793,4.021520229759403,-0.6104587700422,0.26227740933927773,0.29216707088500893,-0.2972292063859285 | 3,417 |
Parkinsons disease | 21 | 55 | 2.315045 | 0.02061 | P13073,P00846,P12235,P03886,Q9Y277,P24539,O43676,O95168,P00403,P51970,P21796,O95139,P22695,O43674,P45880,P14406,P20674,P25705,P12236,Q9Y6M9,P21912 | Processes and pathways | KEGG Pathways | msigdb_kegg | 255,5,519,25,162,289,37,556,175,558,60,185,206,213,92,93,603,477,613,515,378 | 3377,1431,1872,213,37,2200,1669,763,772,1360,1614,185,556,3346,1636,1133,175,5,25,889,621,1171,2608,1111,519,613,255,93,1877,1060,3224,3311,603,60,378,3158,206,289,477,3339,2436,2532,1952,3215,92,3293,3326,558,2501,3073,2996,1044,2594,162,515 | -1.9777750442589752,-0.012231339448816497,-0.23294462613289643,1.6416384181662695,3.139895912874602,-0.3783778232336641,-0.13755014327896972,0.4836099334246191,0.46905485711054756,0.034225377321387807,-0.10602215649073785,1.753353058227572,0.7549694526938922,-1.5818830601858436,-0.12176944730407814,0.1718878508968803,1.8024946555524302,4.150512780930534,3.334140571921885,0.3515923455547478,0.6561209993607429,0.1415142579959687,-0.5768530736707557,0.18702860941006846,0.8108826859948203,0.6703212128832107,1.464604471440723,2.5049291611996107,-0.23294462613289643,0.21721872733739006,-1.134002123850734,-1.3918689663666952,0.684494911792463,2.855552391486076,1.097890201205585,-1.0262403613136382,1.6790550002814526,1.3615958927095713,0.8939906762605774,-1.543475472466397,-0.4935045244272046,-0.5434002923310789,-0.26501721992446775,-1.1159302783535316,2.5161229900221445,-1.2987125719306165,-1.4483470542519512,0.7549694526938922,-0.5267307699032723,-0.9025053658548252,-0.8327318119520807,0.23226835470484916,-0.5601076639663766,1.8877553948021577,0.8247970828574156 | 3,417 |
Glycosaminoglycan metabolism | 8 | 16 | 2.2957 | 0.021693 | O43505,Q8TB61,P15586,P54802,Q7LGA3,P06865,P08236,Q8NCH0 | Processes and pathways | Reactome Pathways | msigdb_reactome | 357,102,205,77,208,144,243,62 | 2199,357,1129,144,1490,243,205,373,1272,988,77,208,62,102,703,899 | -0.3783778232336641,1.1646687956946997,0.1718878508968803,1.9720970491130785,-0.04336396950002838,1.5028819314367052,1.6790550002814526,1.1112924650776037,0.0803949197759099,0.26227740933927773,2.6382261887100418,1.6790550002814526,2.855552391486076,2.3465341395617054,0.5559678555775356,0.3515923455547478 | 3,417 |
Sphingolipid metabolic process | 18 | 33 | 2.275666 | 0.022866 | P04062,P50897,Q06136,O15269,P06280,Q6Y1H2,Q16880,P06865,P07602,Q13510,Q96G23,Q9NRA0,P17900,O95470,Q16739,P16278,Q8NCC3,Q9NZJ7 | Processes and pathways | GO Biological process | msigdb_gobp | 160,1,484,446,232,522,145,144,23,61,56,407,221,153,115,373,285,343 | 3368,446,1833,153,160,232,144,23,1490,373,221,1557,1637,667,1708,1,484,908,1137,61,115,145,817,522,285,56,553,407,1694,1826,343,3375,940 | -1.8968144751645826,0.9488974456277595,-0.21696018972606024,1.911945842266695,1.8877553948021577,1.5536262730798323,1.9720970491130785,3.3844919984080626,-0.04336396950002838,1.1112924650776037,1.6040409488013108,-0.07462717308757696,-0.12176944730407814,0.5990528096837081,-0.15336440011844105,4.205184051711286,0.8802020758474672,0.3367799639890156,0.1718878508968803,2.855552391486076,2.16154041194842,1.9720970491130785,0.42522051928811844,0.8108826859948203,1.3745472757064856,2.8876479191575553,0.7689863138513828,1.0440457330659343,-0.13755014327896972,-0.20101010976855774,1.2308721605709914,-1.957448063960899,0.32193837550732557 | 3,417 |
Tetrapyrrole binding | 10 | 18 | 2.267818 | 0.02334 | O15173,Q8WUJ1,O43169,P30519,Q6UW02,P09601,P53701,Q16850,O00264,Q9H7Z7 | Functions | GO Molecular function | msigdb_gomf | 0,387,12,13,338,51,404,55,26,349 | 26,0,12,1171,51,1992,13,404,55,338,496,387,1542,2916,2786,349,1548,1053 | 3.3240326367824573,4.205184051711286,3.6705334914046763,0.1415142579959687,2.9196154491336292,-0.28110570611391306,3.6705334914046763,1.0440457330659343,2.8876479191575553,1.24404475743253,0.8525498970089892,1.0710152307117244,-0.058979174610651705,-0.763618598810603,-0.6781350933421636,1.2044591471962716,-0.058979174610651705,0.23226835470484916 | 3,417 |
Leukocyte migration | 9 | 52 | 2.266757 | 0.023405 | P35613,P04062,P14174,P05067,P09601,P00813,Q08722,Q9H4A6,Q8N5M9 | Processes and pathways | GO Biological process | msigdb_gobp | 352,160,43,241,51,22,344,157,259 | 1832,3063,1132,22,160,2160,241,1253,1435,1555,51,43,3203,852,1176,3049,985,1308,2695,352,3102,1232,2858,1259,2383,2125,1998,2022,1117,1387,1409,1999,1410,1848,344,2213,3384,1238,1505,1140,1419,259,1721,1446,1859,360,1513,2515,157,2429,2715,2650 | -0.21696018972606024,-0.9025053658548252,0.1718878508968803,3.4245492778183855,1.8877553948021577,-0.3620767158842694,1.5155991816321197,0.09572162059983903,-0.012231339448816497,-0.07462717308757696,2.9196154491336292,3.0462276398142834,-1.0979033771886262,0.3811299898070121,0.1415142579959687,-0.8849993132602134,0.26227740933927773,0.06503674048205203,-0.6273194417875337,1.1779551385349927,-0.9376441237503343,0.11101698401404882,-0.729305370654242,0.09572162059983903,-0.46042744525232726,-0.3458114723662479,-0.28110570611391306,-0.2972292063859285,0.18702860941006846,0.018771906383900746,0.003286382816216437,-0.28110570611391306,0.003286382816216437,-0.21696018972606024,1.2176769854892084,-0.3783778232336641,-2.039108471107347,0.11101698401404882,-0.04336396950002838,0.1718878508968803,0.003286382816216437,1.464604471440723,-0.15336440011844105,-0.012231339448816497,-0.21696018972606024,1.1646687956946997,-0.04336396950002838,-0.5267307699032723,1.8998599645471619,-0.4769474308147848,-0.6273194417875337,-0.5936367117645664 | 3,417 |
Myoclonic seizure | 11 | 52 | 2.25696 | 0.024011 | P04062,P00846,Q96N66,P16278,P07602,P03886,P21912,O75503,Q13510,Q9NZJ7,Q9Y619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 160,5,307,373,23,25,378,155,61,343,159 | 1832,2082,1943,1432,1799,1379,2046,155,5,25,160,23,1490,373,378,2436,2051,1881,3385,2207,971,2312,2583,2832,531,583,2173,2358,61,3194,2503,3329,396,2177,2132,2103,2448,997,1900,2289,3166,307,886,1203,343,1376,3060,981,1486,1124,732,159 | -0.21696018972606024,-0.32958192020084226,-0.26501721992446775,-0.012231339448816497,-0.20101010976855774,0.018771906383900746,-0.31338788818645713,1.8998599645471619,4.150512780930534,3.334140571921885,1.8877553948021577,3.3844919984080626,-0.04336396950002838,1.1112924650776037,1.097890201205585,-0.4935045244272046,-0.31338788818645713,-0.23294462613289643,-2.1425284599508747,-0.3783778232336641,0.27723709916112255,-0.4274980724879269,-0.5601076639663766,-0.7122088737255577,0.7969428272052425,0.7127631981492363,-0.3620767158842694,-0.4439443859497023,2.855552391486076,-1.0799211761036647,-0.5267307699032723,-1.4483470542519512,1.0575423433134081,-0.3620767158842694,-0.3458114723662479,-0.32958192020084226,-0.4935045244272046,0.26227740933927773,-0.23294462613289643,-0.41108832580523696,-1.0262403613136382,1.3095720089588463,0.3663756458799081,0.1415142579959687,1.2308721605709914,0.034225377321387807,-0.8849993132602134,0.27723709916112255,-0.027781407508477674,0.18702860941006846,0.5271077117058275,1.8998599645471619 | 3,417 |
Abnormal exteroceptive sensation | 8 | 53 | 2.24747 | 0.02461 | P07196,P06280,P54802,Q9H6K4,P07602,O95831,Q9NZ08,Q8NCH0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 224,232,77,20,23,54,158,62 | 1029,446,1833,958,1799,1084,3157,54,749,2526,1764,241,3188,232,224,23,1490,2267,2268,2657,3049,2272,2436,1337,721,1709,2207,2905,77,2352,2315,1676,948,1927,929,1041,1411,2358,1964,2503,3195,2176,2029,1421,62,1263,3166,2515,20,158,343,2923,2524 | 0.23226835470484916,0.9488974456277595,-0.21696018972606024,0.29216707088500893,-0.20101010976855774,0.20213885674598203,-1.0262403613136382,2.8876479191575553,0.49813702297415485,-0.5434002923310789,-0.18509422483019053,1.5155991816321197,-1.0799211761036647,1.5536262730798323,1.591467929576324,3.3844919984080626,-0.04336396950002838,-0.41108832580523696,-0.41108832580523696,-0.6104587700422,-0.8849993132602134,-0.41108832580523696,-0.4935045244272046,0.04964694067544423,0.5271077117058275,-0.15336440011844105,-0.3783778232336641,-0.763618598810603,2.6382261887100418,-0.4439443859497023,-0.4274980724879269,-0.13755014327896972,0.3070674535939185,-0.2489635815987443,0.32193837550732557,0.23226835470484916,0.003286382816216437,-0.4439443859497023,-0.26501721992446775,-0.5267307699032723,-1.0799211761036647,-0.3620767158842694,-0.2972292063859285,0.003286382816216437,2.855552391486076,0.09572162059983903,-1.0262403613136382,-0.5267307699032723,3.4544630581633307,1.8998599645471619,1.2308721605709914,-0.763618598810603,-0.5267307699032723 | 3,417 |
Cis golgi network | 12 | 20 | 2.245393 | 0.024743 | Q14789,O00461,Q96JB2,O43731,Q9UNK9,P24390,Q8TBA6,P49755,Q9NPR9,Q08379,O95249,Q9Y3A6 | Localization | GO Cellular component | msigdb_gocc | 507,288,354,132,529,41,78,494,81,340,123,384 | 288,1945,132,123,41,604,494,973,340,507,1416,1185,1096,78,1781,1859,354,81,529,384 | 1.3615958927095713,-0.26501721992446775,2.0555410573517667,2.1146058237037426,3.0879925141608315,0.684494911792463,0.8525498970089892,0.27723709916112255,1.2308721605709914,0.8247970828574156,0.003286382816216437,0.1415142579959687,0.20213885674598203,2.6272029760773212,-0.18509422483019053,-0.21696018972606024,1.1779551385349927,2.6051106796220176,0.8108826859948203,1.0844644864570787 | 3,417 |
Sphingolipid metabolism | 16 | 29 | 2.240666 | 0.025048 | Q9NRA0,P04062,P51648,O15269,P06280,Q16880,P06865,Q16739,P10619,Q96G23,P07602,P17900,O95470,P16278,Q13510,Q9NZJ7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 407,160,36,446,232,145,144,115,85,56,23,221,153,373,61,343 | 1697,3368,446,1833,693,2796,153,160,232,144,23,1490,85,373,221,1637,667,36,484,61,115,145,2673,56,2844,407,1694,343,940 | -0.15336440011844105,-1.8968144751645826,0.9488974456277595,-0.21696018972606024,0.5559678555775356,-0.6951521821407869,1.911945842266695,1.8877553948021577,1.5536262730798323,1.9720970491130785,3.3844919984080626,-0.04336396950002838,2.5607412932011338,1.1112924650776037,1.6040409488013108,-0.12176944730407814,0.5990528096837081,3.1502366120869385,0.8802020758474672,2.855552391486076,2.16154041194842,1.9720970491130785,-0.6104587700422,2.8876479191575553,-0.7122088737255577,1.0440457330659343,-0.13755014327896972,1.2308721605709914,0.32193837550732557 | 3,417 |
Regulation of mitochondrion organization | 15 | 52 | 2.234576 | 0.025445 | O60313,Q9Y6C9,P10909,Q9H3K2,O00165,Q96HS1,P30536,P02545,P12235,P32121,Q9NUQ9,P21796,Q9H4A6,O14737,Q96A26 | Processes and pathways | GO Biological process | msigdb_gobp | 542,388,639,40,298,331,521,393,519,478,107,60,157,414,31 | 298,1832,414,1301,542,1131,393,1673,2526,889,639,984,519,2306,60,667,2573,1767,521,478,3011,3180,1178,1365,1743,908,951,1317,860,1471,2912,2393,2135,1721,31,331,1787,2594,1194,1102,40,157,1824,1982,107,3155,2560,839,1268,840,1080,388 | 1.3226108940757686,-0.21696018972606024,1.0169809765122253,0.06503674048205203,0.7829774041493419,0.1718878508968803,1.0575423433134081,-0.13755014327896972,-0.5434002923310789,0.3515923455547478,0.6276405919776796,0.26227740933927773,0.8108826859948203,-0.4274980724879269,2.855552391486076,0.5990528096837081,-0.5601076639663766,-0.18509422483019053,0.8108826859948203,0.8939906762605774,-0.8501127548246629,-1.0619834328894011,0.1415142579959687,0.034225377321387807,-0.16921237464871447,0.3367799639890156,0.3070674535939185,0.06503674048205203,0.3811299898070121,-0.027781407508477674,-0.763618598810603,-0.46042744525232726,-0.3458114723662479,-0.15336440011844105,3.2733028146585346,1.2571948605736722,-0.18509422483019053,-0.5601076639663766,0.1415142579959687,0.20213885674598203,3.0983999731344345,1.8998599645471619,-0.20101010976855774,-0.26501721992446775,2.243009135530369,-1.0084345585434802,-0.5434002923310789,0.41055230371744406,0.09572162059983903,0.41055230371744406,0.21721872733739006,1.0710152307117244 | 3,417 |
Glycosphingolipid metabolic process | 7 | 11 | 2.233425 | 0.025521 | P04062,P06280,Q16880,Q16739,P06865,P16278,P17900 | Processes and pathways | GO Biological process | msigdb_gobp | 160,232,145,115,144,373,221 | 160,232,144,1490,373,221,908,1137,115,145,553 | 1.8877553948021577,1.5536262730798323,1.9720970491130785,-0.04336396950002838,1.1112924650776037,1.6040409488013108,0.3367799639890156,0.1718878508968803,2.16154041194842,1.9720970491130785,0.7689863138513828 | 3,417 |
Mitochondrial nucleotide transporter subfamily | 8 | 10 | 2.226842 | 0.025958 | O43808,Q70HW3,Q6NUK1,P12235,Q9H2D1,Q9BSK2,Q6KCM7,Q9HC21 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 97,133,199,519,183,24,281,311 | 97,889,519,613,281,199,133,24,183,311 | 2.4599953722597876,0.3515923455547478,0.8108826859948203,0.6703212128832107,1.4003850963299123,1.716292591643401,2.0436746509844026,3.374446699230225,1.7779625412287436,1.2965110453880544 | 3,417 |
Steroid binding | 11 | 24 | 2.224959 | 0.026084 | O15173,Q14108,P04062,Q9H4L5,P45880,O95772,P35610,O15118,O00264,P21796,P61916 | Functions | GO Molecular function | msigdb_gomf | 0,32,160,333,92,50,310,152,26,60,257 | 26,152,0,1917,1635,50,160,579,2116,60,1637,1174,521,310,421,92,257,32,2293,2189,3037,1575,913,333 | 3.3240326367824573,1.911945842266695,4.205184051711286,-0.2489635815987443,-0.12176944730407814,2.93024304140931,1.8877553948021577,0.7127631981492363,-0.3458114723662479,2.855552391486076,-0.12176944730407814,0.1415142579959687,0.8108826859948203,1.2965110453880544,1.003412645073793,2.5161229900221445,1.464604471440723,3.22225286575062,-0.41108832580523696,-0.3620767158842694,-0.8675351827166916,-0.07462717308757696,0.3367799639890156,1.2571948605736722 | 3,417 |
Secretory granule membrane | 23 | 81 | 2.222649 | 0.026239 | P48960,P27105,Q9NQX7,P30519,P61026,P07602,O00264,Q5T9A4,P11279,Q15363,P10321,P42785,P10253,Q93050,Q08722,Q9NZJ7,O95716,Q07065,Q92542,P35613,O95721,O75787,P49755 | Localization | GO Cellular component | msigdb_gocc | 386,137,138,13,150,23,26,560,46,49,322,323,83,87,344,343,467,91,223,352,476,364,494 | 3062,26,3368,1916,3251,1610,2823,1358,1127,1612,2372,364,2751,467,476,749,23,2161,83,322,46,890,813,3189,683,892,137,13,1496,2164,352,2724,323,1309,386,494,816,1310,737,3071,1066,150,1460,2637,1998,2022,2729,1409,559,91,344,2358,1682,2216,2542,1012,49,1416,1140,2911,560,677,1471,1242,1446,223,87,834,3175,936,1163,1577,138,729,343,940,3324,1027,1794,827,1400 | -0.9025053658548252,3.3240326367824573,-1.8968144751645826,-0.2489635815987443,-1.2067439070369332,-0.10602215649073785,-0.7122088737255577,0.034225377321387807,0.1718878508968803,-0.10602215649073785,-0.46042744525232726,1.1380269980204456,-0.6611574063587524,0.9077544157121817,0.8939906762605774,0.49813702297415485,3.3844919984080626,-0.3620767158842694,2.582956910707055,1.2703225540070913,2.9831709549906043,0.3515923455547478,0.42522051928811844,-1.0799211761036647,0.5703567612440847,0.3515923455547478,2.007967460097441,3.6705334914046763,-0.04336396950002838,-0.3620767158842694,1.1779551385349927,-0.6442189217896607,1.2703225540070913,0.06503674048205203,1.0710152307117244,0.8525498970089892,0.42522051928811844,0.06503674048205203,0.5126362434312117,-0.9025053658548252,0.21721872733739006,1.9360617738820296,-0.027781407508477674,-0.5936367117645664,-0.28110570611391306,-0.2972292063859285,-0.6442189217896607,0.003286382816216437,0.7549694526938922,2.5273010692633533,1.2176769854892084,-0.4439443859497023,-0.13755014327896972,-0.3783778232336641,-0.5434002923310789,0.24728787146509176,2.951456094882685,0.003286382816216437,0.1718878508968803,-0.763618598810603,0.7549694526938922,0.5847183748800465,-0.027781407508477674,0.11101698401404882,-0.012231339448816497,1.6040409488013108,2.5607412932011338,0.41055230371744406,-1.0440899073566592,0.32193837550732557,0.15671644585303687,-0.07462717308757696,2.007967460097441,0.5271077117058275,1.2308721605709914,0.32193837550732557,-1.4294716859918053,0.24728787146509176,-0.18509422483019053,0.42522051928811844,0.018771906383900746 | 3,417 |
Late endosome | 25 | 79 | 2.203533 | 0.027557 | Q9BRK5,Q15012,P07711,Q9UEU0,P07602,O15118,Q7Z3C6,Q14108,Q9HC07,O14964,P35670,Q9BXS4,P11279,O95772,O15400,Q8IV08,Q96PU5,Q9BUN8,O14653,Q9NZJ7,P20645,Q9GZP9,Q99538,Q9HD42,Q96A57 | Localization | GO Cellular component | msigdb_gocc | 130,2,140,539,23,152,282,32,34,540,420,431,46,50,447,69,204,84,464,343,220,355,360,502,124 | 2777,464,540,152,447,2628,2265,50,1875,23,140,2116,2161,1254,564,46,890,813,1334,220,1176,985,420,2499,3180,1310,629,737,1460,1342,2385,951,32,2,700,1141,677,282,69,2103,996,1570,124,2333,912,204,1787,2293,360,1905,130,84,3411,1197,2189,431,3037,355,1295,1607,1481,34,502,1548,2192,729,3143,343,3026,1696,1608,539,3324,2773,901,1580,1794,1667,3376 | -0.6781350933421636,0.9077544157121817,0.7829774041493419,1.911945842266695,0.9488974456277595,-0.5936367117645664,-0.41108832580523696,2.93024304140931,-0.23294462613289643,3.3844919984080626,1.98407208930781,-0.3458114723662479,-0.3620767158842694,0.09572162059983903,0.7409267164122499,2.9831709549906043,0.3515923455547478,0.42522051928811844,0.04964694067544423,1.616593655517,0.1415142579959687,0.26227740933927773,1.003412645073793,-0.5267307699032723,-1.0619834328894011,0.06503674048205203,0.6418941622736091,0.5126362434312117,-0.027781407508477674,0.04964694067544423,-0.46042744525232726,0.3070674535939185,3.22225286575062,4.205184051711286,0.5559678555775356,0.1718878508968803,0.5847183748800465,1.4003850963299123,2.7367552921523206,-0.32958192020084226,0.26227740933927773,-0.07462717308757696,2.1028283105039307,-0.4274980724879269,0.3367799639890156,1.6914873258283896,-0.18509422483019053,-0.41108832580523696,1.1646687956946997,-0.23294462613289643,2.0673895675906206,2.582956910707055,-5.949729985797729,0.1415142579959687,-0.3620767158842694,0.9898202205128834,-0.8675351827166916,1.1779551385349927,0.0803949197759099,-0.09030811624826095,-0.027781407508477674,3.181179420737425,0.8386861195013237,-0.058979174610651705,-0.3620767158842694,0.5271077117058275,-0.9906722647822158,1.2308721605709914,-0.8501127548246629,-0.13755014327896972,-0.09030811624826095,0.7969428272052425,-1.4294716859918053,-0.6611574063587524,0.3515923455547478,-0.07462717308757696,-0.18509422483019053,-0.12176944730407814,-1.957448063960899 | 3,417 |
EF-hand domain [IPR002048] | 12 | 46 | 2.194173 | 0.028223 | O95302,Q9BRK5,O75071,Q9Y680,Q6NUK1,O95202,Q9NWM8,P41208,O43852,P80303,Q02818,Q14257 | Sequence | InterPro Domain | interpro_domain | 129,130,67,99,199,170,271,235,267,17,218,219 | 904,267,67,1333,873,170,129,3085,1803,735,3365,1737,3355,1804,1496,1361,235,2245,605,855,17,218,3164,857,219,2975,1319,2506,281,199,2393,2135,452,1242,961,647,1021,130,964,895,271,977,941,787,759,99 | 0.3367799639890156,1.4261368498464053,2.7693299190267147,0.04964694067544423,0.3663756458799081,1.8391489210251506,2.0673895675906206,-0.920053561687098,-0.20101010976855774,0.5126362434312117,-1.8366943974697396,-0.16921237464871447,-1.6788137614948677,-0.20101010976855774,-0.04336396950002838,0.034225377321387807,1.5536262730798323,-0.3947149681833086,0.684494911792463,0.3811299898070121,3.5828325800136342,1.629126121507551,-1.0262403613136382,0.3811299898070121,1.629126121507551,-0.8153921382152115,0.06503674048205203,-0.5267307699032723,1.4003850963299123,1.716292591643401,-0.46042744525232726,-0.3458114723662479,0.9488974456277595,0.11101698401404882,0.29216707088500893,0.6276405919776796,0.24728787146509176,2.0673895675906206,0.29216707088500893,0.3515923455547478,1.4261368498464053,0.27723709916112255,0.32193837550732557,0.46905485711054756,0.49813702297415485,2.403467854798666 | 3,417 |
calmodulin-related | 6 | 13 | 2.193328 | 0.028284 | Q9BRK5,P41208,O43852,P80303,Q02818,Q14257 | Functions | Panther Protein class | panther_protein_class | 130,235,267,17,218,219 | 267,1803,1496,1361,235,2660,17,218,219,1319,452,1021,130 | 1.4261368498464053,-0.20101010976855774,-0.04336396950002838,0.034225377321387807,1.5536262730798323,-0.6104587700422,3.5828325800136342,1.629126121507551,1.629126121507551,0.06503674048205203,0.9488974456277595,0.24728787146509176,2.0673895675906206 | 3,417 |
Abnormal retinal artery morphology | 11 | 26 | 2.191667 | 0.028404 | P21964,P00846,P06865,P10619,P16278,P07602,P17900,P03886,Q13510,Q9NZJ7,Q8NFV4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 66,5,144,85,373,23,221,25,61,343,191 | 2820,1835,5,25,144,23,1490,85,2692,373,221,66,919,2309,2725,2123,2477,61,1157,191,1656,2450,400,343,2458,760 | -0.7122088737255577,-0.21696018972606024,4.150512780930534,3.334140571921885,1.9720970491130785,3.3844919984080626,-0.04336396950002838,2.5607412932011338,-0.6273194417875337,1.1112924650776037,1.6040409488013108,2.790972813120915,0.32193837550732557,-0.4274980724879269,-0.6442189217896607,-0.3458114723662479,-0.5100989092650228,2.855552391486076,0.15671644585303687,1.7410191359493292,-0.12176944730407814,-0.4935045244272046,1.0575423433134081,1.2308721605709914,-0.4935045244272046,0.49813702297415485 | 3,417 |
Organelle fusion | 21 | 51 | 2.189131 | 0.028587 | Q86Y82,Q9Y6C9,Q12981,Q9UEU0,O60313,O43752,Q9BSR8,P06493,O15400,Q9Y4W6,Q9NX63,O14653,O60499,Q8TB36,O95721,P51809,P31751,Q8NAN2,Q8IWA4,Q969M3,O95249 | Processes and pathways | GO Biological process | msigdb_gobp | 383,388,275,539,542,165,806,697,447,732,474,464,89,348,476,737,233,365,756,376,123 | 3062,464,447,165,542,2153,89,2406,982,1084,123,476,1673,2160,697,1875,1736,233,1310,2379,737,1642,908,950,275,1280,2764,2912,383,756,365,348,2738,376,1194,806,1102,1295,1982,3143,474,1696,1731,539,1079,901,1580,840,1667,732,388 | -0.9025053658548252,0.9077544157121817,0.9488974456277595,1.8513288969813924,0.7829774041493419,-0.3620767158842694,2.5273010692633533,-0.4769474308147848,0.26227740933927773,0.20213885674598203,2.1146058237037426,0.8939906762605774,-0.13755014327896972,-0.3620767158842694,0.5559678555775356,-0.23294462613289643,-0.16921237464871447,1.5536262730798323,0.06503674048205203,-0.46042744525232726,0.5126362434312117,-0.12176944730407814,0.3367799639890156,0.3070674535939185,1.4132716921952186,0.0803949197759099,-0.6611574063587524,-0.763618598810603,1.0844644864570787,0.49813702297415485,1.1380269980204456,1.2044591471962716,-0.6442189217896607,1.1112924650776037,0.1415142579959687,0.43986026964991953,0.20213885674598203,0.0803949197759099,-0.26501721992446775,-0.9906722647822158,0.9077544157121817,-0.13755014327896972,-0.15336440011844105,0.7969428272052425,0.21721872733739006,0.3515923455547478,-0.07462717308757696,0.41055230371744406,-0.12176944730407814,0.5271077117058275,1.0710152307117244 | 3,417 |
Oxidative phosphorylation | 20 | 62 | 2.183808 | 0.028976 | P13073,P00846,Q9BSK2,P03886,P24539,O43676,Q9H3K2,O95168,P00403,P51970,O75964,O95139,P56134,P22695,O43674,P14406,P20674,P25705,Q7KZN9,Q9Y6M9 | Processes and pathways | GO Biological process | msigdb_gobp | 255,5,24,25,289,37,40,556,175,558,53,185,449,206,213,93,603,477,496,515 | 3377,1431,1872,213,37,2200,1669,2689,763,772,1360,1614,53,185,556,3346,1636,1133,175,5,25,697,621,1171,1228,1111,255,93,1255,1877,1060,3224,3311,603,206,289,477,1404,3339,2573,2436,2532,1639,1952,1337,3293,3326,558,2315,449,906,1998,2996,1044,2508,496,2594,24,3345,40,1079,515 | -1.9777750442589752,-0.012231339448816497,-0.23294462613289643,1.6416384181662695,3.139895912874602,-0.3783778232336641,-0.13755014327896972,-0.6273194417875337,0.4836099334246191,0.46905485711054756,0.034225377321387807,-0.10602215649073785,2.8983179291537704,1.753353058227572,0.7549694526938922,-1.5818830601858436,-0.12176944730407814,0.1718878508968803,1.8024946555524302,4.150512780930534,3.334140571921885,0.5559678555775356,0.6561209993607429,0.1415142579959687,0.11101698401404882,0.18702860941006846,1.464604471440723,2.5049291611996107,0.09572162059983903,-0.23294462613289643,0.21721872733739006,-1.134002123850734,-1.3918689663666952,0.684494911792463,1.6790550002814526,1.3615958927095713,0.8939906762605774,0.003286382816216437,-1.543475472466397,-0.5601076639663766,-0.4935045244272046,-0.5434002923310789,-0.12176944730407814,-0.26501721992446775,0.04964694067544423,-1.2987125719306165,-1.4483470542519512,0.7549694526938922,-0.4274980724879269,0.9488974456277595,0.3367799639890156,-0.28110570611391306,-0.8327318119520807,0.23226835470484916,-0.5267307699032723,0.8525498970089892,-0.5601076639663766,3.374446699230225,-1.5626535235419077,3.0983999731344345,0.21721872733739006,0.8247970828574156 | 3,417 |
Intrinsic component of golgi membrane | 7 | 11 | 2.172174 | 0.029843 | Q9Y282,O43505,Q8TB61,O15258,O95070,Q969X5,Q6ZRP7 | Localization | GO Cellular component | msigdb_gocc | 70,357,102,433,308,188,316 | 455,433,357,308,973,1072,2700,316,102,188,70 | 0.9352077032562823,0.9762036088666618,1.1646687956946997,1.2965110453880544,0.27723709916112255,0.21721872733739006,-0.6273194417875337,1.2834279212620188,2.3465341395617054,1.753353058227572,2.7367552921523206 | 3,417 |
Respiratory failure | 17 | 73 | 2.171346 | 0.029905 | Q70HW3,Q5XKP0,Q96PY6,Q92804,P35637,Q9H9S5,P10253,P53701,Q9NZJ7,Q68CQ7,P07602,P06753,P61916,Q9NSD9,Q13510,Q15165,Q9Y619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 133,396,400,266,197,381,83,404,343,117,23,371,257,28,61,29,159 | 577,2085,1669,2373,2087,2796,371,23,2203,1058,83,1615,3189,2162,3213,2854,1231,1362,197,2310,2952,923,2246,2577,1365,1276,2351,404,2380,2315,3136,2353,257,1680,951,61,724,1181,29,859,1894,1649,396,117,133,2590,934,597,882,3373,416,1422,266,1447,3208,1572,400,1145,562,1933,2398,616,2485,381,2297,28,343,1266,1665,1580,1831,159,2299 | 0.7127631981492363,-0.32958192020084226,-0.13755014327896972,-0.46042744525232726,-0.32958192020084226,-0.6951521821407869,1.1112924650776037,3.3844919984080626,-0.3783778232336641,0.21721872733739006,2.582956910707055,-0.10602215649073785,-1.0799211761036647,-0.3620767158842694,-1.1159302783535316,-0.729305370654242,0.11101698401404882,0.034225377321387807,1.716292591643401,-0.4274980724879269,-0.7980935194597194,0.32193837550732557,-0.3947149681833086,-0.5601076639663766,0.034225377321387807,0.0803949197759099,-0.4439443859497023,1.0440457330659343,-0.46042744525232726,-0.4274980724879269,-0.9906722647822158,-0.4439443859497023,1.464604471440723,-0.13755014327896972,0.3070674535939185,2.855552391486076,0.5271077117058275,0.1415142579959687,3.2936329120887344,0.3811299898070121,-0.23294462613289643,-0.12176944730407814,1.0575423433134081,2.1498329700173007,2.0436746509844026,-0.5601076639663766,0.32193837550732557,0.6986422043532152,0.3663756458799081,-1.9371792171939057,1.0169809765122253,0.003286382816216437,1.43898064729436,-0.012231339448816497,-1.0979033771886262,-0.07462717308757696,1.0575423433134081,0.1718878508968803,0.7549694526938922,-0.2489635815987443,-0.46042744525232726,0.6703212128832107,-0.5100989092650228,1.097890201205585,-0.41108832580523696,3.3240326367824573,1.2308721605709914,0.09572162059983903,-0.12176944730407814,-0.07462717308757696,-0.20101010976855774,1.8998599645471619,-0.41108832580523696 | 3,417 |
Exocytic vesicle | 17 | 42 | 2.163307 | 0.030518 | Q86Y82,P50897,O43752,O15400,Q9UI14,Q9BVK6,P11279,P05067,Q9UEU0,O43760,Q9BT78,P61026,P51790,O95716,O60499,Q96A57,Q92542 | Localization | GO Cellular component | msigdb_gocc | 383,1,165,447,171,555,46,241,539,252,214,150,629,467,89,124,223 | 1832,447,165,252,89,1670,467,241,959,2242,1803,46,1949,1153,736,892,2969,1,1310,2379,629,1642,1066,150,1068,950,2956,1239,3016,1091,2130,3270,383,223,671,124,214,555,1102,539,171,2234 | -0.21696018972606024,0.9488974456277595,1.8513288969813924,1.477384651987338,2.5273010692633533,-0.13755014327896972,0.9077544157121817,1.5155991816321197,0.29216707088500893,-0.3947149681833086,-0.20101010976855774,2.9831709549906043,-0.26501721992446775,0.15671644585303687,0.5126362434312117,0.3515923455547478,-0.8153921382152115,4.205184051711286,0.06503674048205203,-0.46042744525232726,0.6418941622736091,-0.12176944730407814,0.21721872733739006,1.9360617738820296,0.21721872733739006,0.3070674535939185,-0.7980935194597194,0.11101698401404882,-0.8501127548246629,0.20213885674598203,-0.3458114723662479,-1.2250442111451176,1.0844644864570787,1.6040409488013108,0.5990528096837081,2.1028283105039307,1.6416384181662695,0.7689863138513828,0.20213885674598203,0.7969428272052425,1.8391489210251506,-0.3783778232336641 | 3,417 |
Monovalent inorganic cation homeostasis | 14 | 31 | 2.162643 | 0.030569 | Q9HC07,P50897,Q8N511,P05023,Q96PU5,O75787,Q92544,P05026,Q9Y6M7,P06576,Q9Y487,Q93050,O75503,Q9Y5X3 | Processes and pathways | GO Biological process | msigdb_gobp | 34,1,101,579,204,364,237,518,601,621,149,87,155,318 | 155,364,1381,918,579,518,621,1172,1176,985,1,1310,629,2055,1259,1068,1889,932,101,237,87,2333,204,1293,34,899,1939,149,318,3043,601 | 1.8998599645471619,1.1380269980204456,0.018771906383900746,0.32193837550732557,0.7127631981492363,0.8108826859948203,0.6561209993607429,0.1415142579959687,0.1415142579959687,0.26227740933927773,4.205184051711286,0.06503674048205203,0.6418941622736091,-0.31338788818645713,0.09572162059983903,0.21721872733739006,-0.23294462613289643,0.32193837550732557,2.369356778832258,1.5409712780565834,2.5607412932011338,-0.4274980724879269,1.6914873258283896,0.0803949197759099,3.181179420737425,0.3515923455547478,-0.2489635815987443,1.9480919530847027,1.2834279212620188,-0.8675351827166916,0.6986422043532152 | 3,417 |
Protein localization to endoplasmic reticulum | 11 | 39 | 2.148158 | 0.031701 | Q9UHQ4,P51572,O43731,Q9NQC3,Q96HY6,P24390,P46379,Q9Y5M8,P61026,Q13438,Q15629 | Processes and pathways | GO Biological process | msigdb_gobp | 327,256,132,39,104,41,207,111,150,379,30 | 1109,433,693,132,1034,2465,2347,2117,1739,41,622,2500,207,1996,256,2697,2759,2439,1809,2125,150,2582,379,740,2667,30,1419,1421,1859,104,1354,1372,1607,39,940,1246,1026,327,111 | 0.18702860941006846,0.9762036088666618,0.5559678555775356,2.0555410573517667,0.23226835470484916,-0.5100989092650228,-0.4439443859497023,-0.3458114723662479,-0.16921237464871447,3.0879925141608315,0.6561209993607429,-0.5267307699032723,1.6790550002814526,-0.28110570611391306,1.464604471440723,-0.6273194417875337,-0.6611574063587524,-0.4935045244272046,-0.20101010976855774,-0.3458114723662479,1.9360617738820296,-0.5601076639663766,1.097890201205585,0.5126362434312117,-0.6104587700422,3.2936329120887344,0.003286382816216437,0.003286382816216437,-0.21696018972606024,2.3006903741988816,0.04964694067544423,0.034225377321387807,-0.09030811624826095,3.1087940046652425,0.32193837550732557,0.11101698401404882,0.24728787146509176,1.2703225540070913,2.1849032261929904 | 3,417 |
Hypocholesterolemia | 6 | 7 | 2.145812 | 0.031888 | Q9NVI7,Q9UBM7,P37268,Q15800,P07602,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 196,599,652,246,23,343 | 23,652,721,246,196,343,599 | 3.3844919984080626,0.6133601781301887,0.5271077117058275,1.5028819314367052,1.7286656697551432,1.2308721605709914,0.6986422043532152 | 3,417 |
Sphingolipid pathway | 8 | 11 | 2.143852 | 0.032045 | P04062,O15269,Q16880,Q16739,Q96G23,Q9NRA0,O95470,Q13510 | Processes and pathways | WikiPathways | msigdb_wp | 160,446,145,115,56,407,153,61 | 446,1833,153,160,3268,484,61,115,145,56,407 | 0.9488974456277595,-0.21696018972606024,1.911945842266695,1.8877553948021577,-1.2250442111451176,0.8802020758474672,2.855552391486076,2.16154041194842,1.9720970491130785,2.8876479191575553,1.0440457330659343 | 3,417 |
Ventricular arrhythmia | 13 | 40 | 2.141952 | 0.032197 | O43772,Q9HD47,P00846,P19022,P02545,P50402,P21912,P09493,P00403,P10253,Q9Y4J8,P03886,P42892 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 483,229,5,485,393,268,378,394,175,83,514,25,90 | 483,1669,3157,175,5,393,25,1381,2267,394,1803,83,519,813,1615,3189,485,378,1231,1258,3160,1336,90,987,815,1365,1501,268,928,3164,1368,1414,1509,1016,1447,2333,2139,1101,229,514 | 0.8802020758474672,-0.13755014327896972,-1.0262403613136382,1.8024946555524302,4.150512780930534,1.0575423433134081,3.334140571921885,0.018771906383900746,-0.41108832580523696,1.0575423433134081,-0.20101010976855774,2.582956910707055,0.8108826859948203,0.42522051928811844,-0.10602215649073785,-1.0799211761036647,0.8663885158422502,1.097890201205585,0.11101698401404882,0.09572162059983903,-1.0262403613136382,0.04964694067544423,2.5273010692633533,0.26227740933927773,0.42522051928811844,0.034225377321387807,-0.04336396950002838,1.4261368498464053,0.32193837550732557,-1.0262403613136382,0.034225377321387807,0.003286382816216437,-0.04336396950002838,0.24728787146509176,-0.012231339448816497,-0.4274980724879269,-0.3458114723662479,0.20213885674598203,1.5788745256641128,0.8247970828574156 | 3,417 |
Abnormality of the achilles tendon | 6 | 13 | 2.132395 | 0.032974 | Q8TD16,P02545,P50402,Q15041,Q9H9S5,Q08J23 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 416,393,268,114,381,127 | 542,393,268,127,114,1505,1369,416,1016,1422,1101,381,1124 | 0.7829774041493419,1.0575423433134081,1.4261368498464053,2.079220240747637,2.16154041194842,-0.04336396950002838,0.034225377321387807,1.0169809765122253,0.24728787146509176,0.003286382816216437,0.20213885674598203,1.097890201205585,0.18702860941006846 | 3,417 |
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins | 22 | 62 | 2.12805 | 0.033333 | P13073,P00846,P03886,P24539,O43676,O95168,P00403,P51970,Q9NPL8,O75964,O95139,P56134,O43819,P22695,O75880,O43674,Q9P0J0,P20674,P25705,Q8N8Q8,Q9Y6M9,P21912 | Processes and pathways | Reactome Pathways | msigdb_reactome | 255,5,25,289,37,556,175,558,179,53,185,449,577,206,82,213,610,603,477,106,515,378 | 3377,1431,1872,213,37,577,2200,1669,763,772,1360,82,1614,53,185,556,3346,1636,1133,175,5,25,621,1171,2608,1111,255,2989,1877,1060,3224,3311,603,378,206,289,477,3339,2436,2532,1952,3119,2952,3293,3326,558,449,906,2126,2027,2996,1044,934,106,955,1758,2398,2887,179,1518,610,515 | -1.9777750442589752,-0.012231339448816497,-0.23294462613289643,1.6416384181662695,3.139895912874602,0.7127631981492363,-0.3783778232336641,-0.13755014327896972,0.4836099334246191,0.46905485711054756,0.034225377321387807,2.582956910707055,-0.10602215649073785,2.8983179291537704,1.753353058227572,0.7549694526938922,-1.5818830601858436,-0.12176944730407814,0.1718878508968803,1.8024946555524302,4.150512780930534,3.334140571921885,0.6561209993607429,0.1415142579959687,-0.5768530736707557,0.18702860941006846,1.464604471440723,-0.8327318119520807,-0.23294462613289643,0.21721872733739006,-1.134002123850734,-1.3918689663666952,0.684494911792463,1.097890201205585,1.6790550002814526,1.3615958927095713,0.8939906762605774,-1.543475472466397,-0.4935045244272046,-0.5434002923310789,-0.26501721992446775,-0.9552772768646035,-0.7980935194597194,-1.2987125719306165,-1.4483470542519512,0.7549694526938922,0.9488974456277595,0.3367799639890156,-0.3458114723662479,-0.2972292063859285,-0.8327318119520807,0.23226835470484916,0.32193837550732557,2.254579138715145,0.3070674535939185,-0.16921237464871447,-0.46042744525232726,-0.7464418770883892,1.7902382361488205,-0.04336396950002838,0.684494911792463,0.8247970828574156 | 3,417 |
Variable expressivity | 21 | 77 | 2.125288 | 0.033563 | Q70HW3,Q9H061,P02545,P00374,P07602,O95470,P03886,Q8TD16,Q13885,P00403,Q13510,Q9Y263,Q9BVA1,Q6P4A7,Q9NZJ7,P17900,P07196,Q9BUF5,P06753,P04350,Q9H9S5 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 133,8,393,392,23,153,25,416,291,175,61,193,332,210,343,221,224,367,371,250,381 | 3377,1832,3368,904,2046,1946,1084,3045,153,392,175,393,25,250,371,224,23,2241,3115,1228,221,2205,2165,2611,1336,3369,1881,923,987,3104,1500,1843,1924,2122,2315,751,1559,767,2832,1928,2358,775,61,857,2096,291,724,2544,2360,2099,817,1599,860,210,2447,133,488,416,424,1447,367,332,8,1265,381,1730,691,343,2922,786,3219,193,1428,2924,1331,732,1831 | -1.9777750442589752,-0.21696018972606024,-1.8968144751645826,0.3367799639890156,-0.31338788818645713,-0.26501721992446775,0.20213885674598203,-0.8849993132602134,1.911945842266695,1.0575423433134081,1.8024946555524302,1.0575423433134081,3.334140571921885,1.4901437800337045,1.1112924650776037,1.591467929576324,3.3844919984080626,-0.3947149681833086,-0.9552772768646035,0.11101698401404882,1.6040409488013108,-0.3783778232336641,-0.3620767158842694,-0.5768530736707557,0.04964694067544423,-1.9169681408133323,-0.23294462613289643,0.32193837550732557,0.26227740933927773,-0.9376441237503343,-0.04336396950002838,-0.21696018972606024,-0.2489635815987443,-0.3458114723662479,-0.4274980724879269,0.49813702297415485,-0.07462717308757696,0.4836099334246191,-0.7122088737255577,-0.2489635815987443,-0.4439443859497023,0.46905485711054756,2.855552391486076,0.3811299898070121,-0.32958192020084226,1.3615958927095713,0.5271077117058275,-0.5434002923310789,-0.4439443859497023,-0.32958192020084226,0.42522051928811844,-0.09030811624826095,0.3811299898070121,1.6666027871242328,-0.4935045244272046,2.0436746509844026,0.8663885158422502,1.0169809765122253,1.003412645073793,-0.012231339448816497,1.1380269980204456,1.2571948605736722,3.871581837843975,0.09572162059983903,1.097890201205585,-0.15336440011844105,0.5703567612440847,1.2308721605709914,-0.763618598810603,0.46905485711054756,-1.1159302783535316,1.7410191359493292,0.003286382816216437,-0.763618598810603,0.06503674048205203,0.5271077117058275,-0.20101010976855774 | 3,417 |
Cholesterol binding | 7 | 16 | 2.123298 | 0.033729 | Q14108,P21796,O95772,P35610,O15118,P45880,P61916 | Functions | GO Molecular function | msigdb_gomf | 32,60,50,310,152,92,257 | 152,1917,1635,50,2116,60,1174,521,310,92,257,32,3037,1575,913,333 | 1.911945842266695,-0.2489635815987443,-0.12176944730407814,2.93024304140931,-0.3458114723662479,2.855552391486076,0.1415142579959687,0.8108826859948203,1.2965110453880544,2.5161229900221445,1.464604471440723,3.22225286575062,-0.8675351827166916,-0.07462717308757696,0.3367799639890156,1.2571948605736722 | 3,417 |
Osteoarthritis | 7 | 13 | 2.123035 | 0.033751 | Q14108,P04062,P35670,P51798,Q96HY6,P02545,O75844 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,160,420,358,104,393,122 | 1029,122,749,393,160,420,358,32,2218,2136,424,104,1825 | 0.23226835470484916,2.1146058237037426,0.49813702297415485,1.0575423433134081,1.8877553948021577,1.003412645073793,1.1646687956946997,3.22225286575062,-0.3783778232336641,-0.3458114723662479,1.003412645073793,2.3006903741988816,-0.20101010976855774 | 3,417 |
Endoplasmic reticulum golgi intermediate compartment membrane | 16 | 31 | 2.119606 | 0.034039 | P51572,Q9Y282,Q8N511,P61019,P24390,Q96RQ1,P53634,P49755,Q15363,O95070,Q08379,Q9H0U4,O14653,Q10472,Q969X5,Q9Y3A6 | Localization | GO Cellular component | msigdb_gocc | 256,70,101,486,41,362,395,494,49,308,340,406,464,469,188,384 | 464,1916,716,982,308,41,3049,641,494,256,395,486,2023,340,469,1412,1280,2541,49,1416,932,2700,101,188,757,362,555,406,70,384,1006 | 0.9077544157121817,-0.2489635815987443,0.5271077117058275,0.26227740933927773,1.2965110453880544,3.0879925141608315,-0.8849993132602134,0.6276405919776796,0.8525498970089892,1.464604471440723,1.0575423433134081,0.8663885158422502,-0.2972292063859285,1.2308721605709914,0.9077544157121817,0.003286382816216437,0.0803949197759099,-0.5434002923310789,2.951456094882685,0.003286382816216437,0.32193837550732557,-0.6273194417875337,2.369356778832258,1.753353058227572,0.49813702297415485,1.151359444691466,0.7689863138513828,1.0440457330659343,2.7367552921523206,1.0844644864570787,0.26227740933927773 | 3,417 |
Transport vesicle | 40 | 101 | 2.116786 | 0.034278 | Q86Y82,P50897,O43731,P49257,Q9UEU0,P61026,Q92905,Q9H0U4,Q9UKR5,O00461,O43752,P24390,Q9BVK6,Q9UI14,P11279,Q99523,Q15363,Q9GZM5,P04439,P10321,O15400,Q8TBA6,Q9NV96,Q9NR31,Q9BT78,O14653,O95716,O60499,O15498,P20645,Q92542,P51809,P20339,P49755,O43493,P05067,O43760,P51790,O95249,Q96A57 | Localization | GO Cellular component | msigdb_gocc | 383,1,132,641,539,150,671,406,413,288,165,41,555,171,46,561,49,178,434,322,447,78,729,598,214,464,467,89,716,220,223,737,736,494,491,241,252,629,123,124 | 1832,288,1223,464,1109,1916,447,716,491,132,2604,165,252,89,3295,2406,1333,982,1670,1671,123,2158,3388,467,3008,749,434,241,959,2242,1803,322,46,890,1949,1153,736,892,220,41,2969,1256,1740,2611,2169,641,494,1,1310,2379,629,737,3071,2755,2725,1642,1066,150,1460,1068,1643,1462,1532,2832,950,1280,2956,1239,3016,1091,2130,49,2252,1814,1416,3270,383,78,223,863,671,124,561,214,555,178,1102,406,1864,598,729,2681,941,539,899,171,413,2234,1006,2044,1081 | -0.21696018972606024,1.3615958927095713,0.11101698401404882,0.9077544157121817,0.18702860941006846,-0.2489635815987443,0.9488974456277595,0.5271077117058275,0.8525498970089892,2.0555410573517667,-0.5768530736707557,1.8513288969813924,1.477384651987338,2.5273010692633533,-1.3172477612728637,-0.4769474308147848,0.04964694067544423,0.26227740933927773,-0.13755014327896972,-0.13755014327896972,2.1146058237037426,-0.3620767158842694,-2.2474878163022267,0.9077544157121817,-0.8501127548246629,0.49813702297415485,0.9762036088666618,1.5155991816321197,0.29216707088500893,-0.3947149681833086,-0.20101010976855774,1.2703225540070913,2.9831709549906043,0.3515923455547478,-0.26501721992446775,0.15671644585303687,0.5126362434312117,0.3515923455547478,1.616593655517,3.0879925141608315,-0.8153921382152115,0.09572162059983903,-0.16921237464871447,-0.5768530736707557,-0.3620767158842694,0.6276405919776796,0.8525498970089892,4.205184051711286,0.06503674048205203,-0.46042744525232726,0.6418941622736091,0.5126362434312117,-0.9025053658548252,-0.6611574063587524,-0.6442189217896607,-0.12176944730407814,0.21721872733739006,1.9360617738820296,-0.027781407508477674,0.21721872733739006,-0.12176944730407814,-0.027781407508477674,-0.058979174610651705,-0.7122088737255577,0.3070674535939185,0.0803949197759099,-0.7980935194597194,0.11101698401404882,-0.8501127548246629,0.20213885674598203,-0.3458114723662479,2.951456094882685,-0.3947149681833086,-0.20101010976855774,0.003286382816216437,-1.2250442111451176,1.0844644864570787,2.6272029760773212,1.6040409488013108,0.3811299898070121,0.5990528096837081,2.1028283105039307,0.7549694526938922,1.6416384181662695,0.7689863138513828,1.8024946555524302,0.20213885674598203,1.0440457330659343,-0.21696018972606024,0.6986422043532152,0.5271077117058275,-0.6104587700422,0.32193837550732557,0.7969428272052425,0.3515923455547478,1.8391489210251506,1.0305253082286936,-0.3783778232336641,0.26227740933927773,-0.2972292063859285,0.21721872733739006 | 3,417 |
Biliary tract abnormality | 11 | 26 | 2.116181 | 0.034329 | Q14108,P04062,Q5XKP0,O95202,P14174,P02545,O96028,P09601,P07602,Q9NSD9,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,160,396,170,43,393,272,51,23,28,343 | 693,170,272,393,160,23,51,43,3304,1993,1178,947,1530,676,1464,2415,32,470,396,2332,1019,28,343,979,1428,1522 | 0.5559678555775356,1.8391489210251506,1.4132716921952186,1.0575423433134081,1.8877553948021577,3.3844919984080626,2.9196154491336292,3.0462276398142834,-1.373141051779376,-0.28110570611391306,0.1415142579959687,0.3070674535939185,-0.058979174610651705,0.5847183748800465,-0.027781407508477674,-0.4769474308147848,3.22225286575062,0.9077544157121817,1.0575423433134081,-0.4274980724879269,0.24728787146509176,3.3240326367824573,1.2308721605709914,0.27723709916112255,0.003286382816216437,-0.04336396950002838 | 3,417 |
Postural tremor | 6 | 18 | 2.113356 | 0.03457 | Q14108,P00846,O14773,P35637,Q9H6K4,P03886 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,5,164,197,20,25 | 164,3084,1669,717,1084,2796,5,25,250,1113,197,2352,1411,32,1783,2594,20,942 | 1.8513288969813924,-0.920053561687098,-0.13755014327896972,0.5271077117058275,0.20213885674598203,-0.6951521821407869,4.150512780930534,3.334140571921885,1.4901437800337045,0.18702860941006846,1.716292591643401,-0.4439443859497023,0.003286382816216437,3.22225286575062,-0.18509422483019053,-0.5601076639663766,3.4544630581633307,0.32193837550732557 | 3,417 |
Abnormal visual electrophysiology | 14 | 53 | 2.095705 | 0.036108 | Q8WWY3,O60313,P50897,P00846,Q04837,P51798,O14773,P12235,P07602,Q96S66,P37198,O75503,Q15067,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 547,542,1,5,550,358,164,519,23,405,530,155,187,343 | 164,1834,1835,693,2463,1302,578,542,155,2986,1918,3258,1084,5,23,519,1920,2575,530,2310,1807,1,1530,358,1772,550,1716,2442,2667,1389,187,777,817,2588,3165,2548,2783,2424,2482,547,1783,2066,1784,405,3200,1102,1372,886,1577,2744,2072,343,3210 | 1.8513288969813924,-0.21696018972606024,-0.21696018972606024,0.5559678555775356,-0.5100989092650228,0.06503674048205203,0.7127631981492363,0.7829774041493419,1.8998599645471619,-0.8327318119520807,-0.2489635815987443,-1.2250442111451176,0.20213885674598203,4.150512780930534,3.3844919984080626,0.8108826859948203,-0.2489635815987443,-0.5601076639663766,0.7969428272052425,-0.4274980724879269,-0.20101010976855774,4.205184051711286,-0.058979174610651705,1.1646687956946997,-0.18509422483019053,0.7689863138513828,-0.15336440011844105,-0.4935045244272046,-0.6104587700422,0.018771906383900746,1.753353058227572,0.46905485711054756,0.42522051928811844,-0.5601076639663766,-1.0262403613136382,-0.5434002923310789,-0.6781350933421636,-0.4769474308147848,-0.5100989092650228,0.7829774041493419,-0.18509422483019053,-0.31338788818645713,-0.18509422483019053,1.0440457330659343,-1.0799211761036647,0.20213885674598203,0.034225377321387807,0.3663756458799081,-0.07462717308757696,-0.6442189217896607,-0.31338788818645713,1.2308721605709914,-1.0979033771886262 | 3,417 |
Copi mediated anterograde transport | 16 | 62 | 2.082198 | 0.037324 | Q14789,Q96JB2,Q13885,O43731,O95249,P24390,Q9BVA1,O75935,P49755,Q9BUF5,Q15363,Q08379,O14653,Q9H0U4,P04350,P68371 | Processes and pathways | Reactome Pathways | msigdb_reactome | 507,354,291,132,123,41,332,172,494,367,49,340,464,406,250,251 | 1223,464,716,2628,132,2406,172,123,250,1134,41,1740,1954,2953,1338,2169,494,1845,3071,2755,1997,1407,1643,1532,2729,251,800,766,1070,340,2781,2095,1280,1215,775,909,857,291,1181,3194,2060,507,49,1779,819,1858,1859,3196,354,1328,367,332,555,406,1980,1695,2681,979,2891,1006,2044,1400 | 0.11101698401404882,0.9077544157121817,0.5271077117058275,-0.5936367117645664,2.0555410573517667,-0.4769474308147848,1.826949932303959,2.1146058237037426,1.4901437800337045,0.1718878508968803,3.0879925141608315,-0.16921237464871447,-0.26501721992446775,-0.7980935194597194,0.04964694067544423,-0.3620767158842694,0.8525498970089892,-0.21696018972606024,-0.9025053658548252,-0.6611574063587524,-0.28110570611391306,0.003286382816216437,-0.12176944730407814,-0.058979174610651705,-0.6442189217896607,1.4901437800337045,0.43986026964991953,0.4836099334246191,0.21721872733739006,1.2308721605709914,-0.6781350933421636,-0.32958192020084226,0.0803949197759099,0.1262811501052972,0.46905485711054756,0.3367799639890156,0.3811299898070121,1.3615958927095713,0.1415142579959687,-1.0799211761036647,-0.31338788818645713,0.8247970828574156,2.951456094882685,-0.18509422483019053,0.42522051928811844,-0.21696018972606024,-0.21696018972606024,-1.0799211761036647,1.1779551385349927,0.06503674048205203,1.1380269980204456,1.2571948605736722,0.7689863138513828,1.0440457330659343,-0.26501721992446775,-0.13755014327896972,-0.6104587700422,0.27723709916112255,-0.7464418770883892,0.26227740933927773,-0.2972292063859285,0.018771906383900746 | 3,417 |
Organophosphate ester transport | 13 | 32 | 2.08047 | 0.037482 | Q14108,O43808,Q08722,Q8TB61,Q6NUK1,Q8WTV0,P61916,Q9HC21,Q9BSK2,Q6KCM7,Q7Z3C6,O00400,Q9H2D1 | Processes and pathways | GO Biological process | msigdb_gobp | 32,97,344,102,199,177,257,311,24,281,282,27,183 | 27,3251,97,889,3114,372,519,613,1637,1174,3125,2613,257,1343,344,32,1140,281,199,282,102,1687,177,757,624,24,1575,913,183,311,729,940 | 3.3240326367824573,-1.2067439070369332,2.4599953722597876,0.3515923455547478,-0.9552772768646035,1.1112924650776037,0.8108826859948203,0.6703212128832107,-0.12176944730407814,0.1415142579959687,-0.972953247696988,-0.5768530736707557,1.464604471440723,0.04964694067544423,1.2176769854892084,3.22225286575062,0.1718878508968803,1.4003850963299123,1.716292591643401,1.4003850963299123,2.3465341395617054,-0.13755014327896972,1.8024946555524302,0.49813702297415485,0.6561209993607429,3.374446699230225,-0.07462717308757696,0.3367799639890156,1.7779625412287436,1.2965110453880544,0.5271077117058275,0.32193837550732557 | 3,417 |
Mitochondrial substrate/solute carrier [IPR018108] | 13 | 21 | 2.070275 | 0.038427 | O43808,O43772,Q9Y6C9,Q70HW3,Q6NUK1,Q9UBX3,P12235,Q9H2D1,Q9BSK2,Q6KCM7,Q9HC21,Q9NZJ7,Q9Y619 | Sequence | InterPro Repeat | interpro_repeat | 97,483,388,133,199,73,519,183,24,281,311,343,159 | 483,97,873,889,519,613,1088,1747,699,281,199,133,24,183,886,311,343,73,787,159,388 | 0.8802020758474672,2.4599953722597876,0.3663756458799081,0.3515923455547478,0.8108826859948203,0.6703212128832107,0.20213885674598203,-0.16921237464871447,0.5559678555775356,1.4003850963299123,1.716292591643401,2.0436746509844026,3.374446699230225,1.7779625412287436,0.3663756458799081,1.2965110453880544,1.2308721605709914,2.6821672119278386,0.46905485711054756,1.8998599645471619,1.0710152307117244 | 3,417 |
Mitochondrial carrier domain superfamily [IPR023395] | 13 | 21 | 2.070275 | 0.038427 | O43808,O43772,Q9Y6C9,Q70HW3,Q6NUK1,Q9UBX3,P12235,Q9H2D1,Q9BSK2,Q6KCM7,Q9HC21,Q9NZJ7,Q9Y619 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 97,483,388,133,199,73,519,183,24,281,311,343,159 | 483,97,873,889,519,613,1088,1747,699,281,199,133,24,183,886,311,343,73,787,159,388 | 0.8802020758474672,2.4599953722597876,0.3663756458799081,0.3515923455547478,0.8108826859948203,0.6703212128832107,0.20213885674598203,-0.16921237464871447,0.5559678555775356,1.4003850963299123,1.716292591643401,2.0436746509844026,3.374446699230225,1.7779625412287436,0.3663756458799081,1.2965110453880544,1.2308721605709914,2.6821672119278386,0.46905485711054756,1.8998599645471619,1.0710152307117244 | 3,417 |
SLC25 family of mitochondrial transporters | 13 | 21 | 2.070275 | 0.038427 | O43808,O43772,Q9Y6C9,Q70HW3,Q6NUK1,Q9UBX3,P12235,Q9H2D1,Q9BSK2,Q6KCM7,Q9HC21,Q9NZJ7,Q9Y619 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 97,483,388,133,199,73,519,183,24,281,311,343,159 | 483,97,873,889,519,613,1088,1747,699,281,199,133,24,183,886,311,343,73,787,159,388 | 0.8802020758474672,2.4599953722597876,0.3663756458799081,0.3515923455547478,0.8108826859948203,0.6703212128832107,0.20213885674598203,-0.16921237464871447,0.5559678555775356,1.4003850963299123,1.716292591643401,2.0436746509844026,3.374446699230225,1.7779625412287436,0.3663756458799081,1.2965110453880544,1.2308721605709914,2.6821672119278386,0.46905485711054756,1.8998599645471619,1.0710152307117244 | 3,417 |
Lipid localization | 21 | 81 | 2.068197 | 0.038622 | Q86Y82,Q9BQE5,P07602,O15118,Q7Z3C6,Q14108,Q9H2V7,P04062,Q9H6V9,P14174,Q8WTV0,P35610,Q9H4L5,Q9NZJ7,P17900,O43808,P31751,P35790,Q16739,P08183,P61916 | Processes and pathways | GO Biological process | msigdb_gobp | 383,3,23,152,282,32,33,160,169,43,177,310,333,343,221,97,233,234,115,372,257 | 1697,3409,152,1916,3251,483,97,3295,2265,2158,2088,638,2897,3260,160,2160,3114,1875,23,1490,2899,372,639,43,221,1637,1174,919,1231,1405,2530,521,233,1062,310,234,2613,1844,257,1408,1343,2539,1592,1137,32,1090,115,1140,677,2063,2282,282,383,3373,177,398,757,2293,2981,1630,3,2844,2189,3037,1575,2814,913,33,333,895,169,729,3143,343,940,548,1664,900,1079,840,1150 | -0.15336440011844105,-3.8861527984573554,1.911945842266695,-0.2489635815987443,-1.2067439070369332,0.8802020758474672,2.4599953722597876,-1.3172477612728637,-0.41108832580523696,-0.3620767158842694,-0.32958192020084226,0.6276405919776796,-0.763618598810603,-1.2250442111451176,1.8877553948021577,-0.3620767158842694,-0.9552772768646035,-0.23294462613289643,3.3844919984080626,-0.04336396950002838,-0.763618598810603,1.1112924650776037,0.6276405919776796,3.0462276398142834,1.6040409488013108,-0.12176944730407814,0.1415142579959687,0.32193837550732557,0.11101698401404882,0.003286382816216437,-0.5434002923310789,0.8108826859948203,1.5536262730798323,0.21721872733739006,1.2965110453880544,1.5536262730798323,-0.5768530736707557,-0.21696018972606024,1.464604471440723,0.003286382816216437,0.04964694067544423,-0.5434002923310789,-0.09030811624826095,0.1718878508968803,3.22225286575062,0.20213885674598203,2.16154041194842,0.1718878508968803,0.5847183748800465,-0.31338788818645713,-0.41108832580523696,1.4003850963299123,1.0844644864570787,-1.9371792171939057,1.8024946555524302,1.0575423433134081,0.49813702297415485,-0.41108832580523696,-0.8153921382152115,-0.10602215649073785,4.205184051711286,-0.7122088737255577,-0.3620767158842694,-0.8675351827166916,-0.07462717308757696,-0.6951521821407869,0.3367799639890156,3.2120040698662837,1.2571948605736722,0.3515923455547478,1.8513288969813924,0.5271077117058275,-0.9906722647822158,1.2308721605709914,0.32193837550732557,0.7829774041493419,-0.12176944730407814,0.3515923455547478,0.21721872733739006,0.41055230371744406,0.1718878508968803 | 3,417 |
Mitochondrial protein import | 19 | 36 | 2.062324 | 0.039177 | O14925,P12235,Q9NS69,O60830,O43615,Q9Y584,P21796,Q99595,Q13505,Q5JRX3,O60220,P62072,Q9NX63,Q15388,Q9Y5J7,Q9Y5J9,P25705,P12236,P06576 | Processes and pathways | Reactome Pathways | msigdb_reactome | 254,519,16,18,541,38,60,63,68,458,578,80,474,594,350,611,477,613,621 | 254,541,578,18,3187,1703,2086,873,2652,1037,621,1171,3321,519,613,60,477,2166,80,676,68,594,952,458,63,3198,1576,16,474,787,1428,1108,38,350,611,761 | 1.464604471440723,0.7829774041493419,0.7127631981492363,3.533699034108947,-1.0799211761036647,-0.15336440011844105,-0.32958192020084226,0.3663756458799081,-0.6104587700422,0.23226835470484916,0.6561209993607429,0.1415142579959687,-1.4294716859918053,0.8108826859948203,0.6703212128832107,2.855552391486076,0.8939906762605774,-0.3620767158842694,2.6161644885369233,0.5847183748800465,2.7367552921523206,0.6986422043532152,0.3070674535939185,0.9352077032562823,2.844825243700939,-1.0799211761036647,-0.07462717308757696,3.5926238292445705,0.9077544157121817,0.46905485711054756,0.003286382816216437,0.20213885674598203,3.139895912874602,1.2044591471962716,0.684494911792463,0.49813702297415485 | 3,417 |
Peripheral axonal neuropathy | 15 | 61 | 2.051996 | 0.04017 | P07196,O60313,Q9NVI7,P00846,O15269,Q8IV08,P22626,P12235,P00403,P07602,O95831,P03886,Q15067,Q9HC21,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 224,542,196,5,446,69,457,519,175,23,54,25,187,311,343 | 446,1833,2114,542,2948,3113,1670,1084,54,175,5,25,1764,224,3085,23,2267,1058,519,2657,457,2570,1639,2051,721,3104,1529,2352,2315,751,1959,1041,2358,1316,775,3194,2731,187,2733,2836,2176,860,2029,2447,2032,69,597,1856,1352,1545,1193,2139,1021,1933,689,311,2072,196,343,732,2524 | 0.9488974456277595,-0.21696018972606024,-0.3458114723662479,0.7829774041493419,-0.7980935194597194,-0.9552772768646035,-0.13755014327896972,0.20213885674598203,2.8876479191575553,1.8024946555524302,4.150512780930534,3.334140571921885,-0.18509422483019053,1.591467929576324,-0.920053561687098,3.3844919984080626,-0.41108832580523696,0.21721872733739006,0.8108826859948203,-0.6104587700422,0.9352077032562823,-0.5601076639663766,-0.12176944730407814,-0.31338788818645713,0.5271077117058275,-0.9376441237503343,-0.058979174610651705,-0.4439443859497023,-0.4274980724879269,0.49813702297415485,-0.26501721992446775,0.23226835470484916,-0.4439443859497023,0.06503674048205203,0.46905485711054756,-1.0799211761036647,-0.6442189217896607,1.753353058227572,-0.6442189217896607,-0.7122088737255577,-0.3620767158842694,0.3811299898070121,-0.2972292063859285,-0.4935045244272046,-0.2972292063859285,2.7367552921523206,0.6986422043532152,-0.21696018972606024,0.04964694067544423,-0.058979174610651705,0.1415142579959687,-0.3458114723662479,0.24728787146509176,-0.2489635815987443,0.5703567612440847,1.2965110453880544,-0.31338788818645713,1.7286656697551432,1.2308721605709914,0.5271077117058275,-0.5267307699032723 | 3,417 |
Carbohydrate derivative transport | 15 | 20 | 2.045898 | 0.040766 | O43808,P12236,Q8TB61,L0R6Q1,Q6NUK1,Q96AA3,P12235,Q8WTV0,P61916,P07602,Q08722,Q6KCM7,O00400,Q9HC21,Q9NZJ7 | Processes and pathways | GO Biological process | msigdb_gobp | 97,613,102,455,199,398,519,177,257,23,344,281,27,311,343 | 455,27,3251,97,889,23,519,613,3125,257,344,281,199,102,1687,177,398,624,311,343 | 0.9352077032562823,3.3240326367824573,-1.2067439070369332,2.4599953722597876,0.3515923455547478,3.3844919984080626,0.8108826859948203,0.6703212128832107,-0.972953247696988,1.464604471440723,1.2176769854892084,1.4003850963299123,1.716292591643401,2.3465341395617054,-0.13755014327896972,1.8024946555524302,1.0575423433134081,0.6561209993607429,1.2965110453880544,1.2308721605709914 | 3,417 |
Golgi apparatus subcompartment | 36 | 105 | 2.03719 | 0.041631 | Q14789,P51572,O15127,Q8NBN3,P61026,Q7Z3C6,Q9H4A6,Q9P260,O00461,Q9HC07,P04062,O43752,P35670,Q8WVQ1,Q9BTU6,Q9BXS4,Q10469,Q15363,P04439,Q4J6C6,P53365,Q8TBA6,Q9NPR9,Q08379,Q10472,O60499,P20645,Q8NBZ7,Q96JB2,Q96ED9,O43493,P05067,Q9NX62,Q969M3,O95249,Q96A57 | Localization | GO Cellular component | msigdb_gocc | 507,256,134,141,150,282,157,548,288,34,160,165,420,424,554,431,429,49,434,451,198,78,81,340,469,89,220,226,354,103,491,241,377,376,123,124 | 2927,288,734,134,491,2604,165,2947,89,1401,2406,2155,123,160,434,241,959,2242,1172,890,892,220,3213,1637,3118,420,673,1954,1529,2379,256,737,198,1340,1773,3205,1642,150,1460,1462,2022,800,973,2832,2094,3322,340,429,1072,469,2861,676,950,2781,2216,2060,507,2130,49,1185,451,3329,1141,282,1189,996,141,226,78,1858,1781,424,2675,1859,2329,376,124,103,354,703,561,3279,806,554,1197,431,936,3004,157,1980,3110,34,81,2869,377,1694,548,900,1732,901,849,2234,2891,2264,2371 | -0.7808357432419631,1.3615958927095713,0.5126362434312117,2.0198879121638424,0.8525498970089892,-0.5768530736707557,1.8513288969813924,-0.7980935194597194,2.5273010692633533,0.003286382816216437,-0.4769474308147848,-0.3620767158842694,2.1146058237037426,1.8877553948021577,0.9762036088666618,1.5155991816321197,0.29216707088500893,-0.3947149681833086,0.1415142579959687,0.3515923455547478,0.3515923455547478,1.616593655517,-1.1159302783535316,-0.12176944730407814,-0.9552772768646035,1.003412645073793,0.5847183748800465,-0.26501721992446775,-0.058979174610651705,-0.46042744525232726,1.464604471440723,0.5126362434312117,1.716292591643401,0.04964694067544423,-0.18509422483019053,-1.0979033771886262,-0.12176944730407814,1.9360617738820296,-0.027781407508477674,-0.027781407508477674,-0.2972292063859285,0.43986026964991953,0.27723709916112255,-0.7122088737255577,-0.32958192020084226,-1.4294716859918053,1.2308721605709914,0.9898202205128834,0.21721872733739006,0.9077544157121817,-0.729305370654242,0.5847183748800465,0.3070674535939185,-0.6781350933421636,-0.3783778232336641,-0.31338788818645713,0.8247970828574156,-0.3458114723662479,2.951456094882685,0.1415142579959687,0.9488974456277595,-1.4483470542519512,0.1718878508968803,1.4003850963299123,0.1415142579959687,0.26227740933927773,1.98407208930781,1.591467929576324,2.6272029760773212,-0.21696018972606024,-0.18509422483019053,1.003412645073793,-0.6104587700422,-0.21696018972606024,-0.4274980724879269,1.1112924650776037,2.1028283105039307,2.3121762578160885,1.1779551385349927,0.5559678555775356,0.7549694526938922,-1.2433909693380374,0.43986026964991953,0.7689863138513828,0.1415142579959687,0.9898202205128834,0.32193837550732557,-0.8327318119520807,1.8998599645471619,-0.26501721992446775,-0.9376441237503343,3.181179420737425,2.6051106796220176,-0.729305370654242,1.1112924650776037,-0.13755014327896972,0.7829774041493419,0.3515923455547478,-0.15336440011844105,0.3515923455547478,0.3958555013531686,-0.3783778232336641,-0.7464418770883892,-0.3947149681833086,-0.4439443859497023 | 3,417 |
Glycosylation | 17 | 53 | 2.022392 | 0.043136 | Q9HC07,P04062,Q96JB2,O43505,Q96AA3,O60502,Q9BXS4,Q9BT22,Q10469,P33908,P46977,Q08379,Q10472,O15118,Q96L58,O75503,Q9H9S5 | Processes and pathways | GO Biological process | msigdb_gobp | 34,160,354,357,398,370,431,562,429,622,274,340,469,152,703,155,381 | 1300,152,2945,357,370,1401,2046,1333,155,1380,160,696,1227,622,2724,274,3405,800,1959,1928,340,429,1072,469,2442,2542,2060,1416,1185,1216,1391,1627,1073,820,1858,398,354,703,562,431,1163,1661,1396,1980,381,34,2428,1912,899,2891,1831,2404,2819 | 0.06503674048205203,1.911945842266695,-0.7980935194597194,1.1646687956946997,1.1112924650776037,0.003286382816216437,-0.31338788818645713,0.04964694067544423,1.8998599645471619,0.018771906383900746,1.8877553948021577,0.5559678555775356,0.11101698401404882,0.6561209993607429,-0.6442189217896607,1.4132716921952186,-3.3200105320612723,0.43986026964991953,-0.26501721992446775,-0.2489635815987443,1.2308721605709914,0.9898202205128834,0.21721872733739006,0.9077544157121817,-0.4935045244272046,-0.5434002923310789,-0.31338788818645713,0.003286382816216437,0.1415142579959687,0.1262811501052972,0.018771906383900746,-0.10602215649073785,0.21721872733739006,0.42522051928811844,-0.21696018972606024,1.0575423433134081,1.1779551385349927,0.5559678555775356,0.7549694526938922,0.9898202205128834,0.15671644585303687,-0.12176944730407814,0.018771906383900746,-0.26501721992446775,1.097890201205585,3.181179420737425,-0.4769474308147848,-0.23294462613289643,0.3515923455547478,-0.7464418770883892,-0.20101010976855774,-0.46042744525232726,-0.6951521821407869 | 3,417 |
Mitochondrial complex iv assembly | 7 | 13 | 2.019285 | 0.043458 | P13073,Q9Y2R0,Q8N8Q8,O43819,Q7KZN9,P00403,P14406 | Processes and pathways | WikiPathways | msigdb_wp | 255,4,106,577,496,175,93 | 1431,577,175,2608,1111,255,93,1060,603,496,106,1758,4 | -0.012231339448816497,0.7127631981492363,1.8024946555524302,-0.5768530736707557,0.18702860941006846,1.464604471440723,2.5049291611996107,0.21721872733739006,0.684494911792463,0.8525498970089892,2.254579138715145,-0.16921237464871447,4.205184051711286 | 3,417 |
Abnormality of head blood vessel | 11 | 30 | 2.017401 | 0.043654 | P21964,P00846,P06865,P10619,P16278,P07602,P17900,P03886,Q13510,Q9NZJ7,Q8NFV4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 66,5,144,85,373,23,221,25,61,343,191 | 2820,3084,1835,5,25,144,23,1490,85,2692,373,221,2118,66,919,2309,3171,2725,2123,2477,61,1157,191,1656,2450,400,1203,343,2458,760 | -0.7122088737255577,-0.920053561687098,-0.21696018972606024,4.150512780930534,3.334140571921885,1.9720970491130785,3.3844919984080626,-0.04336396950002838,2.5607412932011338,-0.6273194417875337,1.1112924650776037,1.6040409488013108,-0.3458114723662479,2.790972813120915,0.32193837550732557,-0.4274980724879269,-1.0440899073566592,-0.6442189217896607,-0.3458114723662479,-0.5100989092650228,2.855552391486076,0.15671644585303687,1.7410191359493292,-0.12176944730407814,-0.4935045244272046,1.0575423433134081,0.1415142579959687,1.2308721605709914,-0.4935045244272046,0.49813702297415485 | 3,417 |
Heterogeneous | 14 | 46 | 2.015901 | 0.04381 | P07196,Q9BQE5,P21964,P00846,P51798,P53634,P25054,P05067,P06753,P03886,Q8TB36,O75844,P61916,Q9Y619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 224,3,66,5,358,395,273,241,371,25,348,122,257,159 | 1032,1129,122,2897,1057,5,749,393,25,2526,1764,241,371,224,890,519,3189,66,273,1273,1675,2658,2310,3162,1365,1529,2207,358,395,2314,257,1239,1368,1181,1389,777,1346,1321,348,3412,3,1482,1911,3219,2197,159 | 0.23226835470484916,0.1718878508968803,2.1146058237037426,-0.763618598810603,0.21721872733739006,4.150512780930534,0.49813702297415485,1.0575423433134081,3.334140571921885,-0.5434002923310789,-0.18509422483019053,1.5155991816321197,1.1112924650776037,1.591467929576324,0.3515923455547478,0.8108826859948203,-1.0799211761036647,2.790972813120915,1.4132716921952186,0.0803949197759099,-0.13755014327896972,-0.6104587700422,-0.4274980724879269,-1.0262403613136382,0.034225377321387807,-0.058979174610651705,-0.3783778232336641,1.1646687956946997,1.0575423433134081,-0.4274980724879269,1.464604471440723,0.11101698401404882,0.034225377321387807,0.1415142579959687,0.018771906383900746,0.46905485711054756,0.04964694067544423,0.06503674048205203,1.2044591471962716,-7.033092352380706,4.205184051711286,-0.027781407508477674,-0.23294462613289643,-1.1159302783535316,-0.3620767158842694,1.8998599645471619 | 3,417 |
Mhc protein binding | 6 | 9 | 2.010903 | 0.044336 | P07437,P25705,P51572,Q9NUQ9,Q9BUN8,P68371 | Functions | GO Molecular function | msigdb_gomf | 225,477,256,107,84,251 | 621,225,477,256,2315,251,2023,84,107 | 0.6561209993607429,1.591467929576324,0.8939906762605774,1.464604471440723,-0.4274980724879269,1.4901437800337045,-0.2972292063859285,2.582956910707055,2.243009135530369 | 3,417 |
Cellular monovalent inorganic cation homeostasis | 13 | 28 | 2.009092 | 0.044527 | Q9HC07,P50897,Q8N511,P05023,Q96PU5,O75787,Q92544,P05026,Q9Y6M7,P06576,Q9Y487,Q93050,O75503 | Processes and pathways | GO Biological process | msigdb_gobp | 34,1,101,579,204,364,237,518,601,621,149,87,155 | 155,364,918,579,518,621,1172,1176,985,1,1310,629,2055,1259,1068,1889,932,101,237,87,2333,204,34,899,1939,149,3043,601 | 1.8998599645471619,1.1380269980204456,0.32193837550732557,0.7127631981492363,0.8108826859948203,0.6561209993607429,0.1415142579959687,0.1415142579959687,0.26227740933927773,4.205184051711286,0.06503674048205203,0.6418941622736091,-0.31338788818645713,0.09572162059983903,0.21721872733739006,-0.23294462613289643,0.32193837550732557,2.369356778832258,1.5409712780565834,2.5607412932011338,-0.4274980724879269,1.6914873258283896,3.181179420737425,0.3515923455547478,-0.2489635815987443,1.9480919530847027,-0.8675351827166916,0.6986422043532152 | 3,417 |
Outer membrane | 28 | 94 | 2.008446 | 0.044596 | Q9Y6C9,Q5XKP0,O43169,P30536,P50402,Q9NS69,O00264,Q9Y277,O60313,Q9UKU0,O00165,P09601,Q9HCL2,P21796,Q13505,Q8WY22,Q96HS1,Q9UBM7,Q9NX63,P57105,Q9NZJ7,Q8TB36,P45880,Q9NZ45,Q9NQZ5,Q8NAN2,Q9BWH2,Q07820 | Localization | GO Cellular component | msigdb_gocc | 388,396,12,521,268,16,26,162,542,418,298,51,59,60,68,200,331,599,474,212,343,348,92,100,231,365,109,506 | 298,26,1832,3409,12,542,2493,2689,1703,2652,1084,2088,1037,1704,3261,2568,51,2657,60,521,1062,2166,720,2952,92,268,1844,1440,3136,212,2021,908,506,1316,68,1505,594,2587,645,817,1893,2255,396,684,702,1471,1159,756,2393,2135,803,1392,365,882,348,1016,200,1190,331,1193,783,1194,1020,1630,1861,999,109,1822,3319,1102,2743,59,1548,1824,1982,231,16,1692,1910,1220,3155,474,1694,100,343,1551,599,1579,418,162,3028,840,1108,388 | 1.3226108940757686,3.3240326367824573,-0.21696018972606024,-3.8861527984573554,3.6705334914046763,0.7829774041493419,-0.5267307699032723,-0.6273194417875337,-0.15336440011844105,-0.6104587700422,0.20213885674598203,-0.32958192020084226,0.23226835470484916,-0.15336440011844105,-1.2250442111451176,-0.5601076639663766,2.9196154491336292,-0.6104587700422,2.855552391486076,0.8108826859948203,0.21721872733739006,-0.3620767158842694,0.5271077117058275,-0.7980935194597194,2.5161229900221445,1.4261368498464053,-0.21696018972606024,-0.012231339448816497,-0.9906722647822158,1.6541306164984428,-0.2972292063859285,0.3367799639890156,0.8247970828574156,0.06503674048205203,2.7367552921523206,-0.04336396950002838,0.6986422043532152,-0.5601076639663766,0.6276405919776796,0.42522051928811844,-0.23294462613289643,-0.3947149681833086,1.0575423433134081,0.5703567612440847,0.5559678555775356,-0.027781407508477674,0.15671644585303687,0.49813702297415485,-0.46042744525232726,-0.3458114723662479,0.43986026964991953,0.018771906383900746,1.1380269980204456,0.3663756458799081,1.2044591471962716,0.24728787146509176,1.716292591643401,0.1415142579959687,1.2571948605736722,0.1415142579959687,0.46905485711054756,0.1415142579959687,0.24728787146509176,-0.10602215649073785,-0.21696018972606024,0.26227740933927773,2.196558711059144,-0.20101010976855774,-1.4106457509822412,0.20213885674598203,-0.6442189217896607,2.8662651920293465,-0.058979174610651705,-0.20101010976855774,-0.26501721992446775,1.5662606644900365,3.5926238292445705,-0.13755014327896972,-0.23294462613289643,0.1262811501052972,-1.0084345585434802,0.9077544157121817,-0.13755014327896972,2.3921138117979415,1.2308721605709914,-0.058979174610651705,0.6986422043532152,-0.07462717308757696,1.0169809765122253,1.8877553948021577,-0.8501127548246629,0.41055230371744406,0.20213885674598203,1.0710152307117244 | 3,417 |
Sterol binding | 7 | 19 | 2.001344 | 0.045355 | Q14108,P45880,O95772,P35610,O15118,P21796,P61916 | Functions | GO Molecular function | msigdb_gomf | 32,92,50,310,152,60,257 | 152,1917,1635,50,2116,60,1637,1174,521,310,92,257,32,2293,2189,3037,1575,913,333 | 1.911945842266695,-0.2489635815987443,-0.12176944730407814,2.93024304140931,-0.3458114723662479,2.855552391486076,-0.12176944730407814,0.1415142579959687,0.8108826859948203,1.2965110453880544,2.5161229900221445,1.464604471440723,3.22225286575062,-0.41108832580523696,-0.3620767158842694,-0.8675351827166916,-0.07462717308757696,0.3367799639890156,1.2571948605736722 | 3,417 |
Oxidative phosphorylation | 21 | 60 | 1.991529 | 0.046423 | P13073,P00846,Q9Y487,P03886,P24539,O43676,O95168,P00403,P51970,O75964,O95139,P56134,P22695,Q93050,O43674,P14406,P20674,P25705,Q7KZN9,Q9Y6M9,P21912 | Processes and pathways | KEGG Pathways | msigdb_kegg | 255,5,149,25,289,37,556,175,558,53,185,449,206,87,213,93,603,477,496,515,378 | 3377,1431,1872,213,37,2200,1669,763,772,1360,1614,53,185,556,3346,1636,1133,175,5,25,621,1171,2608,1111,255,93,1877,1060,3224,3311,603,2243,3342,378,206,289,477,3339,2436,2532,1952,1063,2611,3293,3326,558,449,906,1068,3362,932,2996,1044,496,87,3094,1939,149,827,515 | -1.9777750442589752,-0.012231339448816497,-0.23294462613289643,1.6416384181662695,3.139895912874602,-0.3783778232336641,-0.13755014327896972,0.4836099334246191,0.46905485711054756,0.034225377321387807,-0.10602215649073785,2.8983179291537704,1.753353058227572,0.7549694526938922,-1.5818830601858436,-0.12176944730407814,0.1718878508968803,1.8024946555524302,4.150512780930534,3.334140571921885,0.6561209993607429,0.1415142579959687,-0.5768530736707557,0.18702860941006846,1.464604471440723,2.5049291611996107,-0.23294462613289643,0.21721872733739006,-1.134002123850734,-1.3918689663666952,0.684494911792463,-0.3947149681833086,-1.5626535235419077,1.097890201205585,1.6790550002814526,1.3615958927095713,0.8939906762605774,-1.543475472466397,-0.4935045244272046,-0.5434002923310789,-0.26501721992446775,0.21721872733739006,-0.5768530736707557,-1.2987125719306165,-1.4483470542519512,0.7549694526938922,0.9488974456277595,0.3367799639890156,0.21721872733739006,-1.777078394489823,0.32193837550732557,-0.8327318119520807,0.23226835470484916,0.8525498970089892,2.5607412932011338,-0.920053561687098,-0.2489635815987443,1.9480919530847027,0.42522051928811844,0.8247970828574156 | 3,417 |
Abnormal muscle fiber morphology | 19 | 76 | 1.989034 | 0.046697 | P00846,Q70HW3,P02545,P50402,P12235,P03886,O43676,P00403,Q9H2D1,O95831,P22626,P35637,P07196,Q8NI60,Q5HYK3,O14979,P05067,P06753,Q9H9S5 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 5,133,393,268,519,25,37,175,183,54,457,197,224,488,361,363,241,371,381 | 1431,363,37,2114,542,1333,1735,54,1037,175,5,393,25,3292,241,371,224,2241,1058,764,519,1085,3158,457,1231,2436,1880,197,2951,923,987,268,1529,750,972,1088,2351,2315,948,1959,1928,1716,951,724,3194,3231,2733,361,2131,1186,133,2032,2325,1508,597,1856,488,3244,1016,1193,2139,1630,1021,1145,1101,1861,3345,183,1396,381,2297,1428,1985,732,1522,1831 | -0.012231339448816497,1.1380269980204456,3.139895912874602,-0.3458114723662479,0.7829774041493419,0.04964694067544423,-0.16921237464871447,2.8876479191575553,0.23226835470484916,1.8024946555524302,4.150512780930534,1.0575423433134081,3.334140571921885,-1.2987125719306165,1.5155991816321197,1.1112924650776037,1.591467929576324,-0.3947149681833086,0.21721872733739006,0.4836099334246191,0.8108826859948203,0.20213885674598203,-1.0262403613136382,0.9352077032562823,0.11101698401404882,-0.4935045244272046,-0.23294462613289643,1.716292591643401,-0.7980935194597194,0.32193837550732557,0.26227740933927773,1.4261368498464053,-0.058979174610651705,0.49813702297415485,0.27723709916112255,0.20213885674598203,-0.4439443859497023,-0.4274980724879269,0.3070674535939185,-0.26501721992446775,-0.2489635815987443,-0.15336440011844105,0.3070674535939185,0.5271077117058275,-1.0799211761036647,-1.1521191599990652,-0.6442189217896607,1.151359444691466,-0.3458114723662479,0.1415142579959687,2.0436746509844026,-0.2972292063859285,-0.4274980724879269,-0.04336396950002838,0.6986422043532152,-0.21696018972606024,0.8663885158422502,-1.1702816352075658,0.24728787146509176,0.1415142579959687,-0.3458114723662479,-0.10602215649073785,0.24728787146509176,0.1718878508968803,0.20213885674598203,-0.21696018972606024,-1.5626535235419077,1.7779625412287436,0.018771906383900746,1.097890201205585,-0.41108832580523696,0.003286382816216437,-0.26501721992446775,0.5271077117058275,-0.04336396950002838,-0.20101010976855774 | 3,417 |
Action tremor | 11 | 54 | 1.988728 | 0.046731 | Q14108,P00846,O14773,Q5JRX3,P35637,O75787,Q9H6K4,P07602,P03886,P04350,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,5,164,458,197,364,20,23,25,250,343 | 2792,164,3084,693,1702,1669,717,364,1084,2796,5,25,2653,250,23,2899,2349,2780,1113,1174,3068,2574,197,3125,3126,1843,2122,2352,1070,1411,32,776,2444,458,1284,3233,3366,2177,1369,473,1783,1193,2594,1630,616,20,2646,2848,343,758,942,1942,1080,732 | -0.6951521821407869,1.8513288969813924,-0.920053561687098,0.5559678555775356,-0.15336440011844105,-0.13755014327896972,0.5271077117058275,1.1380269980204456,0.20213885674598203,-0.6951521821407869,4.150512780930534,3.334140571921885,-0.6104587700422,1.4901437800337045,3.3844919984080626,-0.763618598810603,-0.4439443859497023,-0.6781350933421636,0.18702860941006846,0.1415142579959687,-0.9025053658548252,-0.5601076639663766,1.716292591643401,-0.972953247696988,-0.972953247696988,-0.21696018972606024,-0.3458114723662479,-0.4439443859497023,0.21721872733739006,0.003286382816216437,3.22225286575062,0.46905485711054756,-0.4935045244272046,0.9352077032562823,0.0803949197759099,-1.1521191599990652,-1.8366943974697396,-0.3620767158842694,0.034225377321387807,0.9077544157121817,-0.18509422483019053,0.1415142579959687,-0.5601076639663766,-0.10602215649073785,0.6703212128832107,3.4544630581633307,-0.5936367117645664,-0.7122088737255577,1.2308721605709914,0.49813702297415485,0.32193837550732557,-0.2489635815987443,0.21721872733739006,0.5271077117058275 | 3,417 |
Inner mitochondrial membrane organization | 16 | 25 | 1.98869 | 0.046735 | Q16891,O60313,Q5XKP0,Q9Y584,Q13505,Q9H3K2,O95202,O60220,Q9Y4W6,P62072,Q9NX63,Q9Y5J7,P17152,Q6UXV4,Q9Y5J9,Q9P0J0 | Processes and pathways | GO Biological process | msigdb_gobp | 645,542,396,38,68,40,170,578,732,80,474,350,468,702,611,610 | 578,542,1703,2652,170,468,2166,80,68,645,817,1893,396,702,1782,40,1220,474,610,732,1108,38,350,611,761 | 0.7127631981492363,0.7829774041493419,-0.15336440011844105,-0.6104587700422,1.8391489210251506,0.9077544157121817,-0.3620767158842694,2.6161644885369233,2.7367552921523206,0.6276405919776796,0.42522051928811844,-0.23294462613289643,1.0575423433134081,0.5559678555775356,-0.18509422483019053,3.0983999731344345,0.1262811501052972,0.9077544157121817,0.684494911792463,0.5271077117058275,0.20213885674598203,3.139895912874602,1.2044591471962716,0.684494911792463,0.49813702297415485 | 3,417 |
Abnormal biliary tract morphology | 9 | 23 | 1.988084 | 0.046802 | Q14108,P04062,Q5XKP0,P14174,P02545,P09601,P07602,Q9NSD9,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,160,396,43,393,51,23,28,343 | 693,393,160,23,51,43,3304,1993,1178,947,1530,676,1464,32,470,396,2332,1019,28,343,979,1428,1522 | 0.5559678555775356,1.0575423433134081,1.8877553948021577,3.3844919984080626,2.9196154491336292,3.0462276398142834,-1.373141051779376,-0.28110570611391306,0.1415142579959687,0.3070674535939185,-0.058979174610651705,0.5847183748800465,-0.027781407508477674,3.22225286575062,0.9077544157121817,1.0575423433134081,-0.4274980724879269,0.24728787146509176,3.3240326367824573,1.2308721605709914,0.27723709916112255,0.003286382816216437,-0.04336396950002838 | 3,417 |
Dysostosis multiplex | 6 | 9 | 1.987724 | 0.046842 | P54802,P15586,P10619,P16278,P08236,P04066 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 77,205,85,373,243,572 | 637,572,243,85,205,373,988,77,2333 | 0.6276405919776796,0.7268580000891784,1.5028819314367052,2.5607412932011338,1.6790550002814526,1.1112924650776037,0.26227740933927773,2.6382261887100418,-0.4274980724879269 | 3,417 |
Nuclear envelope ne reassembly | 16 | 51 | 1.982632 | 0.047408 | Q13885,Q8NFH4,Q9BVA1,P02545,P50402,Q9BUF5,Q14739,Q8NC56,Q86XL3,Q9BTX1,P37198,Q8IXJ6,P04350,P68371,P42167,Q8N1F7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 291,397,332,393,268,367,470,473,276,342,530,118,250,251,156,608 | 2606,2794,1056,393,250,697,1255,2968,1113,1708,530,791,156,3190,268,2313,1366,1559,1745,1155,251,1962,775,291,470,2618,1894,1262,276,118,608,473,2510,397,1393,1722,1570,2914,1898,615,1901,3279,342,367,332,3001,1513,1607,1580,2402,1667 | -0.5768530736707557,-0.6951521821407869,0.21721872733739006,1.0575423433134081,1.4901437800337045,0.5559678555775356,0.09572162059983903,-0.8153921382152115,0.18702860941006846,-0.15336440011844105,0.7969428272052425,0.45447167559111346,1.8998599645471619,-1.0799211761036647,1.4261368498464053,-0.4274980724879269,0.034225377321387807,-0.07462717308757696,-0.16921237464871447,0.15671644585303687,1.4901437800337045,-0.26501721992446775,0.46905485711054756,1.3615958927095713,0.9077544157121817,-0.5768530736707557,-0.23294462613289643,0.09572162059983903,1.4132716921952186,2.1498329700173007,0.684494911792463,0.9077544157121817,-0.5267307699032723,1.0575423433134081,0.018771906383900746,-0.15336440011844105,-0.07462717308757696,-0.763618598810603,-0.23294462613289643,0.6703212128832107,-0.23294462613289643,-1.2433909693380374,1.2308721605709914,1.1380269980204456,1.2571948605736722,-0.8327318119520807,-0.04336396950002838,-0.09030811624826095,-0.07462717308757696,-0.46042744525232726,-0.12176944730407814 | 3,417 |
Glycoside hydrolase superfamily [IPR017853] | 7 | 16 | 1.973848 | 0.048399 | P04062,P06280,P54802,P10253,P06865,P16278,P08236 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 160,232,77,83,144,373,243 | 370,160,572,232,144,1490,969,243,83,373,2498,77,1041,2544,1977,1197 | 1.1112924650776037,1.8877553948021577,0.7268580000891784,1.5536262730798323,1.9720970491130785,-0.04336396950002838,0.27723709916112255,1.5028819314367052,2.582956910707055,1.1112924650776037,-0.5267307699032723,2.6382261887100418,0.23226835470484916,-0.5434002923310789,-0.26501721992446775,0.1415142579959687 | 3,417 |
Intrinsic component of mitochondrial inner membrane | 21 | 34 | 3.77982 | 0.000157 | Q9Y2R0,O43819,Q16891,O60830,O95563,Q9NX63,Q9H3K2,Q6P4A7,Q99595,P17152,O75880,Q53H12,Q6UXV4,Q5XKP0,Q16134,O14925,Q9HC21,Q15070,Q9UG56,Q13505,Q8N8Q8 | Localization | GO Cellular component | msigdb_gocc | 5,515,529,22,656,546,33,171,52,434,59,443,449,198,584,201,228,100,622,105,108 | 201,515,22,1063,59,656,434,3212,1641,904,105,100,584,529,443,1005,198,171,449,108,1877,1054,769,52,33,1572,1170,228,1154,546,622,5,1273,695 | 1.6993368662863828,0.8227153339568873,3.389160419925041,0.22496634533860416,2.7620488324659895,0.6154905133855352,0.9838731573525725,-1.1303571839723463,-0.11161663697128474,0.3431478364322099,2.301105245667895,2.3658887117772305,0.7268312627826058,0.8091037855865696,0.9705945223247175,0.2695373236736853,1.711216457757838,1.8753114211973756,0.9572887845888515,2.2684732013809596,-0.22249405275792178,0.23985743121252281,0.47357736156305924,2.8923057086966835,3.202436833742072,-0.06467431361864844,0.165057285462392,1.6035173065048012,0.180086585856304,0.7954637182819312,0.6713991887930522,4.079438950901208,0.1045887365929969,0.5732411343760665 | 3,417 |
Lysosomal lumen | 23 | 39 | 3.738584 | 0.000185 | P50897,P17900,P10619,Q8NHP8,P07602,P08236,P06865,O43681,P10253,P07858,P11117,Q8IV08,P04062,Q13510,Q9NZJ7,O14773,P38435,Q9UMR5,Q14108,P54802,P16278,P07711,P06280 | Localization | GO Cellular component | msigdb_gocc | 1,134,388,158,32,289,422,549,170,184,189,450,195,75,335,206,337,82,98,103,376,119,383 | 729,1575,206,549,195,1310,383,422,32,2184,119,184,1690,289,170,388,189,2427,876,915,376,134,1093,337,3344,552,1,2364,103,1344,75,98,450,2406,158,722,1354,335,82 | 0.5164778220540673,-0.080283891168658,1.651602135580465,0.7817950089963721,1.72307457356377,0.07414127779889645,1.0760741454068623,1.010349571326269,3.202436833742072,-0.3842701148909007,2.191697356585309,1.8054866977683843,-0.14310210131811343,1.345112044634575,1.8753114211973756,1.0629820996007722,1.7702938658351084,-0.4999787955465205,0.37235963057923405,0.32849244575329073,1.0891399743619552,2.1140159037622634,0.2100409512222278,1.2055702200831364,-1.5289120558488012,0.7817950089963721,4.079438950901208,-0.46670653209308793,2.333576542930749,0.05886364960372865,2.546060857024669,2.387342541189054,0.9572887845888515,-0.4833211743492699,1.9558464367057236,0.5307152226992892,0.05886364960372865,1.2183796925819346,2.504107696101658 | 3,417 |
Organophosphate ester transport | 15 | 32 | 3.657727 | 0.000254 | Q9HC21,P08183,Q9BSK2,Q14108,Q9H1P3,P12235,O43808,O00400,Q9H2D1,Q08722,Q8TB61,Q6NUK1,Q7Z3C6,Q8WTV0,Q6KCM7 | Processes and pathways | GO Biological process | msigdb_gobp | 228,323,3,98,204,365,236,16,176,84,86,474,316,350,222 | 16,2882,236,775,2225,323,365,470,1993,1381,3072,2117,1344,1068,84,98,1164,222,474,316,86,846,350,799,770,3,691,204,176,228,928,1224 | 3.5618203282976997,-0.7551608870541102,1.567220738704834,0.45921398013028775,-0.4006732349357356,1.2439235324069875,1.1151934116250275,0.9172078124078225,-0.2867183612159623,0.028199720326965952,-0.9132800387870509,-0.3515885852686711,0.05886364960372865,0.22496634533860416,2.493577626661402,2.387342541189054,0.165057285462392,1.6155716241957836,0.9172078124078225,1.2693678996019138,2.4830307358799764,0.4014404547791768,1.1669903758343456,0.44481874473177313,0.47357736156305924,4.079438950901208,0.5732411343760665,1.6874357190816478,1.8521189098662278,1.6035173065048012,0.32849244575329073,0.1348936174475735 | 3,417 |
SLC superfamily of solute carriers | 21 | 45 | 3.599776 | 0.000318 | Q9BSK2,Q70HW3,O00400,Q9HC07,Q9Y619,P30825,Q9H2V7,Q9Y6C9,Q9H2D1,Q15043,Q02978,Q9NZJ7,Q8TB61,Q6NUK1,P12236,Q6KCM7,Q9HC21,P12235,Q9UBX3,O43808,O95202 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 3,142,16,31,36,40,45,305,176,326,456,335,86,474,470,222,228,365,109,236,127 | 16,1723,236,1429,127,656,900,775,1231,365,470,40,3072,879,827,1432,904,456,326,2005,222,474,1970,882,142,798,86,769,770,3,1373,1034,176,1303,45,506,1572,31,228,335,109,1226,36,305,646 | 3.5618203282976997,-0.15890258245488978,1.567220738704834,-0.0026102883160087067,2.1474202525907056,0.6154905133855352,0.3431478364322099,0.45921398013028775,0.1197589134781991,1.1151934116250275,0.9172078124078225,3.1070691737442258,-0.9132800387870509,0.37235963057923405,0.415932129064235,-0.0026102883160087067,0.3431478364322099,0.9439558302360769,1.2439235324069875,-0.2867183612159623,1.6155716241957836,0.9172078124078225,-0.27060224728382676,0.37235963057923405,2.0804411470022126,0.44481874473177313,2.4830307358799764,0.47357736156305924,0.47357736156305924,4.079438950901208,0.043549855895539176,0.25471437049160844,1.8521189098662278,0.08938291553650131,2.9907887060862692,0.8498533620967631,-0.06467431361864844,3.2118986899262745,1.6035173065048012,1.2183796925819346,2.2684732013809596,0.1348936174475735,3.1453808033753354,1.2947135868342938,0.6435049519950851 | 3,417 |
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