term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein insertion into mitochondrial inner membrane | 7 | 9 | 2.346692 | 0.018941 | Q9P0J0,Q9Y5J7,Q9Y5J9,O60220,P62072,Q53H12,Q9Y584 | Processes and pathways | GO Biological process | msigdb_gobp | 419,164,347,460,56,443,30 | 460,2600,56,443,419,30,164,347,477 | 0.9305955446314544,-0.583919668151991,2.7923363998378443,0.9705945223247175,1.0235475745145948,3.221347085581454,1.9214522256714823,1.1798756638524783,0.9172078124078225 | 3,417 |
Nucleobase containing compound transmembrane transporter activity | 10 | 16 | 2.331422 | 0.019731 | Q9HC21,Q9BSK2,P12235,O43808,O00400,Q9H2D1,L0R6Q1,Q8TB61,Q6NUK1,Q6KCM7 | Functions | GO Molecular function | msigdb_gomf | 228,3,365,236,16,176,341,86,474,222 | 341,16,2882,236,775,365,470,3072,1235,222,474,86,770,3,176,228 | 1.1927355777835806,3.5618203282976997,-0.7551608870541102,1.567220738704834,0.45921398013028775,1.1151934116250275,0.9172078124078225,-0.9132800387870509,0.1197589134781991,1.6155716241957836,0.9172078124078225,2.4830307358799764,0.47357736156305924,4.079438950901208,1.8521189098662278,1.6035173065048012 | 3,417 |
Ph reduction | 6 | 13 | 2.328157 | 0.019904 | Q05086,P50897,Q93050,Q9Y487,O75787,Q8N511 | Processes and pathways | GO Biological process | msigdb_gobp | 192,1,135,274,211,95 | 315,211,824,1,1067,779,1644,192,95,135,1457,274,3141 | 1.2693678996019138,1.6396139556611513,0.415932129064235,4.079438950901208,0.22496634533860416,0.45921398013028775,-0.11161663697128474,1.7349112933227129,2.3980433462775825,2.1140159037622634,-0.0026102883160087067,1.4323854934737215,-0.9848254487759778 | 3,417 |
Mitochondrial complex iv assembly | 7 | 13 | 2.326379 | 0.019998 | Q9Y2R0,Q8N8Q8,O43819,Q7KZN9,P14406,P00403,P13073 | Processes and pathways | WikiPathways | msigdb_wp | 5,108,515,333,49,118,186 | 1753,515,118,1955,1232,186,49,1253,600,333,108,1302,5 | -0.17474182156354792,0.8227153339568873,2.191697356585309,-0.27060224728382676,0.1197589134781991,1.7937767070377697,2.9417301538561795,0.1045887365929969,0.6991742787236601,1.2183796925819346,2.2684732013809596,0.08938291553650131,4.079438950901208 | 3,417 |
Abnormal pericardium morphology | 6 | 12 | 2.326087 | 0.020014 | Q14108,P04062,Q9NZ08,P22413,P49748,P14174 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 98,195,270,243,439,28 | 972,1280,502,195,28,243,2029,439,1582,98,1590,270 | 0.2843264501176428,0.08938291553650131,0.8498533620967631,1.72307457356377,3.221347085581454,1.5429108324741363,-0.3028748428550267,0.9705945223247175,-0.080283891168658,2.387342541189054,-0.080283891168658,1.4447586398473278 | 3,417 |
Nucleotide transport | 10 | 16 | 2.310506 | 0.02086 | Q9HC21,Q9BSK2,P12235,O43808,O00400,Q9H2D1,Q08722,Q8TB61,Q6NUK1,Q6KCM7 | Processes and pathways | GO Biological process | msigdb_gobp | 228,3,365,236,16,176,84,86,474,222 | 16,2882,236,775,365,470,3072,84,222,474,86,846,770,3,176,228 | 3.5618203282976997,-0.7551608870541102,1.567220738704834,0.45921398013028775,1.1151934116250275,0.9172078124078225,-0.9132800387870509,2.493577626661402,1.6155716241957836,0.9172078124078225,2.4830307358799764,0.4014404547791768,0.47357736156305924,4.079438950901208,1.8521189098662278,1.6035173065048012 | 3,417 |
Abnormal circulating cholesterol concentration | 11 | 31 | 2.309996 | 0.020888 | P07602,P50402,P48643,Q9UBM7,Q9NVI7,P37268,Q9NZJ7,Q15800,Q15392,Q14739,Q8N511 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,257,447,262,268,299,335,304,147,212,95 | 1063,914,502,953,32,3382,299,3344,2230,447,257,3249,1434,1344,1701,984,1766,212,147,1119,304,634,95,753,1010,1745,268,335,262,1226,2051 | 0.22496634533860416,0.32849244575329073,0.8498533620967631,0.2990819080544139,3.202436833742072,-2.0595692165269956,1.3073496705658783,-1.5289120558488012,-0.4006732349357356,0.9572887845888515,1.481738356319479,-1.2043820778052585,-0.0026102883160087067,0.05886364960372865,-0.14310210131811343,0.2843264501176428,-0.17474182156354792,1.6396139556611513,2.024099644140111,0.1950810860549713,1.2947135868342938,0.6574670293566639,2.3980433462775825,0.48790903352268455,0.2695373236736853,-0.15890258245488978,1.457108438974517,1.2183796925819346,1.4694349811947218,0.1348936174475735,-0.3028748428550267 | 3,417 |
Ceramide metabolic process | 13 | 22 | 2.309011 | 0.020943 | Q96G23,P04062,P17900,Q16880,P06865,Q13510,Q16739,Q99805,Q9NRA0,Q53H12,O95470,O15269,P06280 | Processes and pathways | GO Biological process | msigdb_gobp | 66,195,134,104,422,75,146,668,475,443,187,510,383 | 3364,510,1602,187,195,383,422,2184,134,2057,855,1383,937,75,146,104,443,679,66,668,475,1376 | -1.7278133504168929,0.8362984856412491,-0.09593126943002946,1.7820457887243357,1.72307457356377,1.0760741454068623,1.010349571326269,-0.3842701148909007,2.1140159037622634,-0.3190719005092798,0.38691633847751733,0.028199720326965952,0.3138038545974289,2.546060857024669,2.0466941864597326,2.333576542930749,0.9705945223247175,0.5873548038204078,2.711259409326985,0.6014378848555904,0.9172078124078225,0.043549855895539176 | 3,417 |
EF-hand domain [IPR002048] | 15 | 46 | 2.306858 | 0.021063 | O43852,Q14257,Q9NWM8,Q02818,Q8IYU8,P80303,Q9BRK5,Q9Y680,P0DP25,O95302,P43304,O75071,P41208,Q6KCM7,O95202 | Sequence | InterPro Domain | interpro_domain | 256,227,196,325,425,70,169,411,303,307,338,126,93,222,127 | 1278,256,126,974,1429,127,307,2697,303,935,3373,2567,3010,2470,1413,1611,93,2229,338,571,70,325,2233,1143,227,2612,1568,2581,222,474,2403,1835,425,720,1195,1008,835,169,1011,1269,196,1515,2772,1226,823,411 | 0.08938291553650131,1.481738356319479,2.1474202525907056,0.2843264501176428,-0.0026102883160087067,2.1474202525907056,1.2820530290453684,-0.6348148888478948,1.2947135868342938,0.3138038545974289,-1.8708329390666887,-0.5670436789350108,-0.860139758826078,-0.5166796247488002,0.012813065246235574,-0.09593126943002946,2.4087268221913423,-0.4006732349357356,1.2055702200831364,0.7543711682631408,2.63949253044833,1.2439235324069875,-0.4006732349357356,0.180086585856304,1.6035173065048012,-0.583919668151991,-0.06467431361864844,-0.5670436789350108,1.6155716241957836,0.9172078124078225,-0.4833211743492699,-0.2065373586035809,1.010349571326269,0.5307152226992892,0.14999301851452415,0.2695373236736853,0.415932129064235,1.8984223305480457,0.2695373236736853,0.1045887365929969,1.72307457356377,-0.033567813428752,-0.668970176567426,0.1348936174475735,0.43039150987620567,1.0367189234918222 | 3,417 |
Areflexia of lower limbs | 6 | 22 | 2.302394 | 0.021313 | Q15041,Q9H6K4,O60313,P07196,Q15067,O75787 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 160,34,294,233,117,211 | 294,2328,211,1492,2081,1863,233,365,1562,1111,2119,1673,1347,1499,160,117,1389,553,1652,801,2523,34 | 1.3199613772518044,-0.4501346415467144,1.6396139556611513,-0.033567813428752,-0.33530974411801295,-0.22249405275792178,1.5793419482693727,1.1151934116250275,-0.06467431361864844,0.1950810860549713,-0.3515885852686711,-0.1273401837881595,0.05886364960372865,-0.033567813428752,1.944401687938058,2.202720271552077,0.028199720326965952,0.7817950089963721,-0.11161663697128474,0.44481874473177313,-0.5334238928726274,3.192961477567768 | 3,417 |
Inorganic molecular entity transmembrane transporter activity | 35 | 82 | 2.300741 | 0.021406 | P00846,Q9NVV0,Q93050,P35670,P05023,Q8N4V1,O00400,Q9HD20,Q9Y487,Q13423,P51798,P16615,Q9HC07,P24539,O43681,P06576,O75964,P13073,P45880,P21796,Q15043,Q02978,Q9C0H2,Q9Y277,Q7KZN9,Q96S66,P20674,Q6P4Q7,Q9UM00,Q9UBX3,P12235,Q9H936,P00403,Q9Y6M7,O95202 | Functions | GO Molecular function | msigdb_gomf | 0,645,135,394,511,14,16,145,274,151,403,413,31,162,549,421,51,186,60,69,326,456,202,76,333,346,600,487,623,109,365,506,118,646,127 | 2866,16,1379,2882,549,1605,51,127,118,0,900,511,2224,775,421,2503,2426,1231,1312,824,1232,365,186,413,1928,1559,600,2471,3286,69,1780,162,759,2192,394,1000,979,2924,60,3201,779,639,403,1432,731,843,1644,1259,1213,904,2034,456,151,326,1164,487,333,14,1877,846,1880,135,1054,346,1624,1373,202,1034,1303,506,31,145,645,1488,109,1457,623,76,274,738,3141,646 | -0.7378300187664318,3.5618203282976997,0.028199720326965952,-0.7551608870541102,0.7817950089963721,-0.09593126943002946,2.902220138550719,2.1474202525907056,2.191697356585309,4.079438950901208,0.3431478364322099,0.8362984856412491,-0.4006732349357356,0.45921398013028775,1.010349571326269,-0.5334238928726274,-0.4999787955465205,0.1197589134781991,0.07414127779889645,0.415932129064235,0.1197589134781991,1.1151934116250275,1.7937767070377697,1.0235475745145948,-0.25452629436448265,-0.06467431361864844,0.6991742787236601,-0.5166796247488002,-1.3170501619437505,2.63949253044833,-0.19062001449545884,1.932936974823011,0.47357736156305924,-0.3842701148909007,1.0498637286274306,0.2695373236736853,0.2843264501176428,-0.7899635190956561,2.751922092384719,-1.1119839097372366,0.45921398013028775,0.6435049519950851,1.0367189234918222,-0.0026102883160087067,0.5164778220540673,0.4014404547791768,-0.11161663697128474,0.1045887365929969,0.1348936174475735,0.3431478364322099,-0.3028748428550267,0.9439558302360769,1.9786763260210907,1.2439235324069875,0.165057285462392,0.8903495429355509,1.2183796925819346,3.5707848317991115,-0.22249405275792178,0.4014404547791768,-0.22249405275792178,2.1140159037622634,0.23985743121252281,1.1927355777835806,-0.09593126943002946,0.043549855895539176,1.6993368662863828,0.25471437049160844,0.08938291553650131,0.8498533620967631,3.2118986899262745,2.0579624190940984,0.6435049519950851,-0.018070520659702844,2.2684732013809596,-0.0026102883160087067,0.6713991887930522,2.546060857024669,1.4323854934737215,0.5164778220540673,-0.9848254487759778,0.6435049519950851 | 3,417 |
Protein transporter activity | 8 | 17 | 2.2959 | 0.021682 | O14925,Q9HD20,Q9NS69,Q99595,O60830,P49755,Q9Y5J9,Q9Y584 | Functions | GO Molecular function | msigdb_gomf | 201,145,19,52,22,440,347,30 | 201,22,2600,1177,2945,440,1113,1259,463,633,921,52,145,19,992,30,347 | 1.6993368662863828,3.389160419925041,-0.583919668151991,0.14999301851452415,-0.8074358076237756,0.9705945223247175,0.1950810860549713,0.1045887365929969,0.9305955446314544,0.6574670293566639,0.32849244575329073,2.8923057086966835,2.0579624190940984,3.5258411651536656,0.2843264501176428,3.221347085581454,1.1798756638524783 | 3,417 |
Microbody membrane | 13 | 29 | 2.295562 | 0.021701 | Q8TB36,Q9UKU0,P04035,Q9BY49,Q9Y3D6,P40855,O00116,O43808,Q15067,O15228,P51648,P28288,O75192 | Localization | GO Cellular component | msigdb_gocc | 480,357,741,469,694,237,489,236,117,525,24,570,252 | 489,525,236,2149,252,749,2289,2839,741,1556,570,1132,2259,237,917,24,2118,117,1829,1501,1831,921,480,1299,2011,2767,469,357,694 | 0.8768787712343713,0.8091037855865696,1.567220738704834,-0.36790863721425243,1.4940186536364441,0.48790903352268455,-0.43360527729208703,-0.7205457694435239,0.5022091395121904,-0.06467431361864844,0.7543711682631408,0.180086585856304,-0.41711821570494334,1.567220738704834,0.32849244575329073,3.3614840657953646,-0.3515885852686711,2.202720271552077,-0.2065373586035809,-0.033567813428752,-0.2065373586035809,0.32849244575329073,0.9037925174593933,0.08938291553650131,-0.2867183612159623,-0.668970176567426,0.9305955446314544,1.14114326456016,0.5732411343760665 | 3,417 |
secondary carrier transporter | 7 | 14 | 2.290683 | 0.021982 | Q15043,Q02978,Q9UBX3,O00400,Q9H936,Q8TB61,O95202 | Functions | Panther Protein class | panther_protein_class | 326,456,109,16,506,86,127 | 16,1429,127,900,1432,456,326,1970,86,1373,506,109,1226,646 | 3.5618203282976997,-0.0026102883160087067,2.1474202525907056,0.3431478364322099,-0.0026102883160087067,0.9439558302360769,1.2439235324069875,-0.27060224728382676,2.4830307358799764,0.043549855895539176,0.8498533620967631,2.2684732013809596,0.1348936174475735,0.6435049519950851 | 3,417 |
Nadh dehydrogenase complex assembly | 11 | 26 | 2.29016 | 0.022012 | Q9P0J0,Q9Y6M9,Q15070,O43674,P03886,Q96CU9,O95299,O95139,Q9H061,O95168,O43676 | Processes and pathways | GO Biological process | msigdb_gobp | 419,524,100,229,72,395,420,207,23,561,25 | 3295,229,25,1812,1858,839,1335,207,561,420,889,72,3280,577,100,2759,1369,1074,395,2246,23,2314,1514,419,1549,524 | -1.3360226676213207,1.5914407759518774,3.2777569763908665,-0.2065373586035809,-0.22249405275792178,0.4014404547791768,0.05886364960372865,1.651602135580465,0.7680975338781076,1.010349571326269,0.35777018045817044,2.598130352078956,-1.2981337870876661,0.7406157866680001,2.3658887117772305,-0.668970176567426,0.043549855895539176,0.22496634533860416,1.0498637286274306,-0.4006732349357356,3.3707223205539893,-0.43360527729208703,-0.033567813428752,1.0235475745145948,-0.049102349624348285,0.8227153339568873 | 3,417 |
Glycosidase | 8 | 19 | 2.285808 | 0.022265 | P08236,P04062,P54802,P06865,P10253,O60502,P16278,P06280 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 289,195,103,422,170,174,376,383 | 1575,1576,174,195,1310,383,422,2184,289,170,376,551,1384,103,1260,1419,2679,1500,2657 | -0.080283891168658,-0.080283891168658,1.8521189098662278,1.72307457356377,0.07414127779889645,1.0760741454068623,1.010349571326269,-0.3842701148909007,1.345112044634575,1.8753114211973756,1.0891399743619552,0.7817950089963721,0.028199720326965952,2.333576542930749,0.1045887365929969,0.012813065246235574,-0.617805031632897,-0.033567813428752,-0.6008400388890252 | 3,417 |
Protein localization to mitochondrion | 29 | 68 | 2.284748 | 0.022328 | P49257,Q9NS69,O95831,O60830,P51572,Q9Y584,Q9P0J0,Q9Y5J7,Q9Y3D6,Q9Y512,P0DP25,Q9Y6C9,Q99595,P62072,Q53H12,O14925,O60220,Q9Y5L4,Q9Y5J9,P55786,Q8TB36,O95429,Q15070,Q10713,Q8N8Q8,O43615,Q15388,O00165,O14737 | Processes and pathways | GO Biological process | msigdb_gobp | 650,19,149,22,402,30,419,164,694,695,303,305,52,56,443,201,460,477,347,603,480,610,100,107,108,496,633,245,255 | 245,932,2985,1600,255,201,496,460,22,2327,2600,1492,610,697,149,1177,1690,303,3225,1022,1580,2115,1692,1179,1283,3086,650,1317,402,903,603,56,2476,828,107,937,100,633,2399,1101,443,1479,2067,108,480,1300,2345,52,1624,3138,1079,1660,19,2047,419,2049,2528,1037,1549,1088,694,2142,695,30,164,347,477,305 | 1.5307219638457237,0.3138038545974289,-0.8425236583575074,-0.09593126943002946,1.481738356319479,1.6993368662863828,0.8633800839961283,0.9305955446314544,3.389160419925041,-0.4501346415467144,-0.583919668151991,-0.033567813428752,0.6853015617305336,0.5590967396986621,2.012773197487723,0.14999301851452415,-0.14310210131811343,1.2947135868342938,-1.1487833229977529,0.25471437049160844,-0.080283891168658,-0.3515885852686711,-0.14310210131811343,0.14999301851452415,0.08938291553650131,-0.9310917159637686,0.6295128244024532,0.07414127779889645,1.0367189234918222,0.3431478364322099,0.6991742787236601,2.7923363998378443,-0.5166796247488002,0.415932129064235,2.2902458390004905,0.3138038545974289,2.3658887117772305,0.6574670293566639,-0.4833211743492699,0.2100409512222278,0.9705945223247175,-0.018070520659702844,-0.3190719005092798,2.2684732013809596,0.9037925174593933,0.08938291553650131,-0.4501346415467144,2.8923057086966835,-0.09593126943002946,-0.9848254487759778,0.22496634533860416,-0.11161663697128474,3.5258411651536656,-0.3028748428550267,1.0235475745145948,-0.3028748428550267,-0.5334238928726274,0.25471437049160844,-0.049102349624348285,0.22496634533860416,0.5732411343760665,-0.3515885852686711,0.5732411343760665,3.221347085581454,1.9214522256714823,1.1798756638524783,0.9172078124078225,1.2947135868342938 | 3,417 |
Parkinsonism | 9 | 34 | 2.283707 | 0.022389 | P35637,P07602,P04062,P61457,Q15043,P05067,Q9NZJ7,O75569,O75787 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 384,32,195,324,326,359,335,181,211 | 1811,181,211,1177,195,359,32,2430,2750,2192,384,2756,1673,324,2336,862,1533,1439,1499,1047,326,2239,986,1450,801,2523,3329,481,335,1517,1155,1687,2142,1273 | -0.2065373586035809,1.8171758374827531,1.6396139556611513,0.14999301851452415,1.72307457356377,1.1281812332227774,3.202436833742072,-0.4999787955465205,-0.668970176567426,-0.3842701148909007,1.0760741454068623,-0.668970176567426,-0.1273401837881595,1.2439235324069875,-0.4501346415467144,0.38691633847751733,-0.049102349624348285,-0.0026102883160087067,-0.033567813428752,0.23985743121252281,1.2439235324069875,-0.4006732349357356,0.2843264501176428,-0.0026102883160087067,0.44481874473177313,-0.5334238928726274,-1.451055899206297,0.9037925174593933,1.2183796925819346,-0.033567813428752,0.180086585856304,-0.1273401837881595,-0.3515885852686711,0.1045887365929969 | 3,417 |
Sphingolipid pathway | 8 | 11 | 2.280341 | 0.022587 | Q96G23,P04062,Q16880,Q13510,Q16739,Q06136,Q9NRA0,O95470 | Processes and pathways | WikiPathways | msigdb_wp | 66,195,104,75,146,210,475,187 | 510,1602,187,195,3165,210,75,146,104,66,475 | 0.8362984856412491,-0.09593126943002946,1.7820457887243357,1.72307457356377,-1.0390132878994311,1.651602135580465,2.546060857024669,2.0466941864597326,2.333576542930749,2.711259409326985,0.9172078124078225 | 3,417 |
Abnormal choroid morphology | 11 | 35 | 2.276378 | 0.022823 | Q9H9S5,O14936,Q9Y619,Q96J42,Q5XKP0,Q10713,Q12768,P40855,P53701,P22413,O60826 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 386,539,36,200,198,107,619,237,431,243,592 | 539,973,1925,592,749,2151,2839,2783,657,891,243,2814,2116,1612,237,1725,1467,1582,917,2436,431,1293,1701,107,619,815,198,1350,2009,200,386,1596,1545,1173,36 | 0.7954637182819312,0.2843264501176428,-0.25452629436448265,0.7130174694629439,0.48790903352268455,-0.36790863721425243,-0.7205457694435239,-0.6861161020861396,0.6154905133855352,0.35777018045817044,1.5429108324741363,-0.7033078821496582,-0.3515885852686711,-0.09593126943002946,1.567220738704834,-0.15890258245488978,-0.018070520659702844,-0.080283891168658,0.32849244575329073,-0.4999787955465205,0.9971248028613773,0.08938291553650131,-0.14310210131811343,2.2902458390004905,0.6713991887930522,0.43039150987620567,1.711216457757838,0.05886364960372865,-0.2867183612159623,1.711216457757838,1.0760741454068623,-0.080283891168658,-0.049102349624348285,0.165057285462392,3.1453808033753354 | 3,417 |
Glycerophospholipid biosynthesis | 16 | 34 | 2.272241 | 0.023072 | Q8IV08,Q8NCC3,O14735,Q9UG56,Q9BZF1,Q9HBU6,P43304,Q8NF37,O95674,O15228,Q96N66,P35790,Q53H12,Q9HCL2,Q8NAN2,Q9NQZ5 | Processes and pathways | Reactome Pathways | msigdb_reactome | 450,679,455,622,691,17,338,720,594,525,313,153,443,61,451,221 | 455,525,2254,594,2987,2115,153,1725,338,2790,2117,3013,2892,1239,744,443,1569,987,450,451,679,720,885,313,2486,2487,2382,691,17,61,2560,221,1199,622 | 0.9439558302360769,0.8091037855865696,-0.41711821570494334,0.7130174694629439,-0.8425236583575074,-0.3515885852686711,1.967271292427726,-0.15890258245488978,1.2055702200831364,-0.6861161020861396,-0.3515885852686711,-0.860139758826078,-0.7551608870541102,0.1197589134781991,0.5022091395121904,0.9705945223247175,-0.06467431361864844,0.2843264501176428,0.9572887845888515,0.9572887845888515,0.5873548038204078,0.5307152226992892,0.37235963057923405,1.2820530290453684,-0.5166796247488002,-0.5166796247488002,-0.46670653209308793,0.5732411343760665,3.5618203282976997,2.751922092384719,-0.5502118327072625,1.6276038128114534,0.14999301851452415,0.6713991887930522 | 3,417 |
Cherry red spot of the macula | 6 | 9 | 2.269227 | 0.023255 | P07602,P17900,P10619,Q13510,Q9NZJ7,P16278 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,134,388,75,335,376 | 422,32,2184,388,2604,376,134,75,335 | 1.010349571326269,3.202436833742072,-0.3842701148909007,1.0629820996007722,-0.583919668151991,1.0891399743619552,2.1140159037622634,2.546060857024669,1.2183796925819346 | 3,417 |
Snare complex | 8 | 19 | 2.266949 | 0.023393 | O95249,Q9P2W9,O60499,O14653,O43752,Q12981,O15400,Q9UEU0 | Localization | GO Cellular component | msigdb_gocc | 97,4,39,358,141,249,250,381 | 3142,358,250,758,141,39,1041,97,516,710,2031,1789,249,1295,391,1483,4,381,805 | -1.002837216956381,1.1281812332227774,1.5062759619135841,0.47357736156305924,2.0804411470022126,3.1166678348556403,0.23985743121252281,2.387342541189054,0.8227153339568873,0.5449214820360619,-0.3028748428550267,-0.19062001449545884,1.5185103694031445,0.08938291553650131,1.0629820996007722,-0.018070520659702844,4.079438950901208,1.0891399743619552,0.44481874473177313 | 3,417 |
Dementia | 19 | 63 | 2.263536 | 0.023603 | P35637,P00846,P17900,P35670,Q9Y487,O15118,P21912,P07602,P06865,O60313,P04350,P04062,P03886,Q13510,Q9NZJ7,Q9NQZ5,Q14108,P05067,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 384,0,134,394,274,148,401,32,422,294,319,195,72,75,335,221,98,359,118 | 1600,730,148,549,460,294,1811,1090,1177,118,0,72,195,2725,319,359,422,32,1524,3163,134,1255,401,700,2059,855,2674,1693,384,394,979,2924,2230,1340,2756,2119,1673,1344,1026,2336,862,1439,1499,75,98,1047,1443,2239,986,1504,1299,2765,1450,801,2523,3329,221,335,790,1517,1687,2142,274 | -0.09593126943002946,0.5164778220540673,2.012773197487723,0.7817950089963721,0.9305955446314544,1.3199613772518044,-0.2065373586035809,0.2100409512222278,0.14999301851452415,2.191697356585309,4.079438950901208,2.598130352078956,1.72307457356377,-0.651869854997686,1.256658100316569,1.1281812332227774,1.010349571326269,3.202436833742072,-0.049102349624348285,-1.0390132878994311,2.1140159037622634,0.1045887365929969,1.0367189234918222,0.5590967396986621,-0.3190719005092798,0.38691633847751733,-0.617805031632897,-0.14310210131811343,1.0760741454068623,1.0498637286274306,0.2843264501176428,-0.7899635190956561,-0.4006732349357356,0.05886364960372865,-0.668970176567426,-0.3515885852686711,-0.1273401837881595,0.05886364960372865,0.25471437049160844,-0.4501346415467144,0.38691633847751733,-0.0026102883160087067,-0.033567813428752,2.546060857024669,2.387342541189054,0.23985743121252281,-0.0026102883160087067,-0.4006732349357356,0.2843264501176428,-0.033567813428752,0.08938291553650131,-0.668970176567426,-0.0026102883160087067,0.44481874473177313,-0.5334238928726274,-1.451055899206297,1.6276038128114534,1.2183796925819346,0.45921398013028775,-0.033567813428752,-0.1273401837881595,-0.3515885852686711,1.4323854934737215 | 3,417 |
Ion transport | 31 | 60 | 2.261612 | 0.023721 | P00846,Q9NVV0,P51797,P25705,Q93050,P35670,Q9Y487,P51798,P51790,P16615,P24539,Q8NE01,P06576,O75964,Q9BPX6,P45880,P21796,Q15043,Q8TDW0,P0CG08,Q9C0H2,Q9Y277,Q96S66,Q9Y5K8,P56134,Q6P4Q7,Q9UM00,Q15904,O95202,Q9Y6M7,P05023 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 0,645,639,759,135,394,274,403,779,413,162,426,421,51,835,60,69,326,846,824,202,76,346,738,731,487,623,634,127,646,511 | 2866,1605,51,127,1177,0,900,511,2224,421,824,413,1928,1559,2471,3286,69,1780,162,759,394,1000,979,2924,60,3201,779,639,403,1469,1432,731,843,1644,1213,1584,326,634,1164,487,882,426,1877,846,135,1054,346,835,1078,202,1841,1303,645,1457,623,76,274,738,3141,646 | -0.7378300187664318,-0.09593126943002946,2.902220138550719,2.1474202525907056,0.14999301851452415,4.079438950901208,0.3431478364322099,0.8362984856412491,-0.4006732349357356,1.010349571326269,0.415932129064235,1.0235475745145948,-0.25452629436448265,-0.06467431361864844,-0.5166796247488002,-1.3170501619437505,2.63949253044833,-0.19062001449545884,1.932936974823011,0.47357736156305924,1.0498637286274306,0.2695373236736853,0.2843264501176428,-0.7899635190956561,2.751922092384719,-1.1119839097372366,0.45921398013028775,0.6435049519950851,1.0367189234918222,-0.018070520659702844,-0.0026102883160087067,0.5164778220540673,0.4014404547791768,-0.11161663697128474,0.1348936174475735,-0.080283891168658,1.2439235324069875,0.6574670293566639,0.165057285462392,0.8903495429355509,0.37235963057923405,1.010349571326269,-0.22249405275792178,0.4014404547791768,2.1140159037622634,0.23985743121252281,1.1927355777835806,0.415932129064235,0.22496634533860416,1.6993368662863828,-0.2065373586035809,0.08938291553650131,0.6435049519950851,-0.0026102883160087067,0.6713991887930522,2.546060857024669,1.4323854934737215,0.5164778220540673,-0.9848254487759778,0.6435049519950851 | 3,417 |
Fasciculations | 14 | 40 | 2.260432 | 0.023794 | P35637,P07602,Q969X5,P07196,Q5THJ4,Q13510,O43819,Q9NZJ7,Q9NWS8,Q9BTW9,O95831,Q8TD16,P51114,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 384,32,193,233,555,75,515,335,339,214,149,499,246,383 | 3123,515,2809,149,1863,383,233,32,2184,2840,1524,3145,700,384,246,1673,2544,1439,1499,75,1047,553,555,921,499,1913,193,3095,3096,214,1659,2416,1488,339,1662,335,1517,2219,1687,2594 | -0.9848254487759778,0.8227153339568873,-0.7033078821496582,2.012773197487723,-0.22249405275792178,1.0760741454068623,1.5793419482693727,3.202436833742072,-0.3842701148909007,-0.7205457694435239,-0.049102349624348285,-1.002837216956381,0.5590967396986621,1.0760741454068623,1.5307219638457237,-0.1273401837881595,-0.5502118327072625,-0.0026102883160087067,-0.033567813428752,2.546060857024669,0.23985743121252281,0.7817950089963721,0.7817950089963721,0.32849244575329073,0.8633800839961283,-0.2384902973611259,1.7349112933227129,-0.9310917159637686,-0.9310917159637686,1.6396139556611513,-0.11161663697128474,-0.4833211743492699,-0.018070520659702844,1.2055702200831364,-0.11161663697128474,1.2183796925819346,-0.033567813428752,-0.3842701148909007,-0.1273401837881595,-0.5670436789350108 | 3,417 |
Muscle abnormality related to mitochondrial dysfunction | 11 | 36 | 2.259945 | 0.023825 | P00846,Q9Y2R0,P03886,O60313,Q96CU9,P12235,Q9UBX3,P00403,O43676,Q53H12,Q9NPL8 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,5,72,294,395,365,109,118,25,443,254 | 3295,1753,25,294,1812,1858,748,1335,1407,889,118,0,72,365,3247,3280,2507,3271,762,1342,443,1074,3252,395,2523,1302,2246,1626,3341,254,1514,109,5,2318,1305,524 | -1.3360226676213207,-0.17474182156354792,3.2777569763908665,1.3199613772518044,-0.2065373586035809,-0.22249405275792178,0.48790903352268455,0.05886364960372865,0.012813065246235574,0.35777018045817044,2.191697356585309,4.079438950901208,2.598130352078956,1.1151934116250275,-1.2043820778052585,-1.2981337870876661,-0.5334238928726274,-1.2792732028995302,0.47357736156305924,0.05886364960372865,0.9705945223247175,0.22496634533860416,-1.2043820778052585,1.0498637286274306,-0.5334238928726274,0.08938291553650131,-0.4006732349357356,-0.09593126943002946,-1.5093588210105136,1.4940186536364441,-0.033567813428752,2.2684732013809596,4.079438950901208,-0.43360527729208703,0.08938291553650131,0.8227153339568873 | 3,417 |
Cardiac muscle contraction | 9 | 19 | 2.25244 | 0.024294 | P05023,P06753,P14406,P67936,P22695,P13073,P00403,P16615,P20674 | Processes and pathways | KEGG Pathways | msigdb_kegg | 511,647,49,564,185,186,118,413,600 | 1379,118,511,2224,647,1312,658,1955,1232,186,49,1898,1253,413,600,185,2192,1469,564 | 0.028199720326965952,2.191697356585309,0.8362984856412491,-0.4006732349357356,0.6295128244024532,0.07414127779889645,0.6154905133855352,-0.27060224728382676,0.1197589134781991,1.7937767070377697,2.9417301538561795,-0.2384902973611259,0.1045887365929969,1.0235475745145948,0.6991742787236601,1.8054866977683843,-0.3842701148909007,-0.018070520659702844,0.7680975338781076 | 3,417 |
Macromolecule transmembrane transporter activity | 6 | 14 | 2.246841 | 0.02465 | O14925,Q9NS69,Q99595,O60830,P49755,Q9Y584 | Functions | GO Molecular function | msigdb_gomf | 201,19,52,22,440,30 | 201,22,2600,1177,440,1235,1113,1259,463,633,52,19,992,30 | 1.6993368662863828,3.389160419925041,-0.583919668151991,0.14999301851452415,0.9705945223247175,0.1197589134781991,0.1950810860549713,0.1045887365929969,0.9305955446314544,0.6574670293566639,2.8923057086966835,3.5258411651536656,0.2843264501176428,3.221347085581454 | 3,417 |
Glycoside hydrolase superfamily [IPR017853] | 7 | 16 | 2.232935 | 0.025553 | P08236,P04062,P54802,P10253,O60502,P16278,P06280 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 289,195,103,170,174,376,383 | 174,195,1310,383,422,2184,1231,289,170,376,1384,103,1026,2679,2657,1354 | 1.8521189098662278,1.72307457356377,0.07414127779889645,1.0760741454068623,1.010349571326269,-0.3842701148909007,0.1197589134781991,1.345112044634575,1.8753114211973756,1.0891399743619552,0.028199720326965952,2.333576542930749,0.25471437049160844,-0.617805031632897,-0.6008400388890252,0.05886364960372865 | 3,417 |
Left ventricular hypertrophy | 9 | 26 | 2.227384 | 0.025922 | Q9H9S5,P03886,P10253,P12235,O75787,P00403,P21912,O75880,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 386,72,170,365,211,118,401,59,383 | 932,1063,211,59,118,72,383,170,365,1065,401,2674,1725,3013,983,1473,1419,676,474,1875,2900,1879,1978,2523,386,807 | 0.3138038545974289,0.22496634533860416,1.6396139556611513,2.7620488324659895,2.191697356585309,2.598130352078956,1.0760741454068623,1.8753114211973756,1.1151934116250275,0.22496634533860416,1.0367189234918222,-0.617805031632897,-0.15890258245488978,-0.860139758826078,0.2843264501176428,-0.018070520659702844,0.012813065246235574,0.5873548038204078,0.9172078124078225,-0.22249405275792178,-0.7551608870541102,-0.22249405275792178,-0.27060224728382676,-0.5334238928726274,1.0760741454068623,0.44481874473177313 | 3,417 |
Protein transmembrane transporter activity | 6 | 13 | 2.225568 | 0.026043 | O14925,Q9NS69,Q99595,O60830,P49755,Q9Y584 | Functions | GO Molecular function | msigdb_gomf | 201,19,52,22,440,30 | 201,22,2600,1177,440,1113,1259,463,633,52,19,992,30 | 1.6993368662863828,3.389160419925041,-0.583919668151991,0.14999301851452415,0.9705945223247175,0.1950810860549713,0.1045887365929969,0.9305955446314544,0.6574670293566639,2.8923057086966835,3.5258411651536656,0.2843264501176428,3.221347085581454 | 3,417 |
Postural tremor | 7 | 18 | 2.215962 | 0.026694 | P00846,Q9H6K4,Q14108,P03886,O14773,O75569,P04350 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,34,98,72,206,181,319 | 206,2498,1858,181,1492,2809,0,72,319,1255,384,2119,862,98,1708,3329,34,1155 | 1.651602135580465,-0.5334238928726274,-0.22249405275792178,1.8171758374827531,-0.033567813428752,-0.7033078821496582,4.079438950901208,2.598130352078956,1.256658100316569,0.1045887365929969,1.0760741454068623,-0.3515885852686711,0.38691633847751733,2.387342541189054,-0.14310210131811343,-1.451055899206297,3.192961477567768,0.180086585856304 | 3,417 |
Membrane lipid biosynthetic process | 10 | 26 | 2.213442 | 0.026867 | Q96G23,P04062,Q16880,Q13510,Q16739,Q06136,Q9NRA0,Q6Y1H2,Q53H12,O95470 | Processes and pathways | GO Biological process | msigdb_gobp | 66,195,104,75,146,210,475,444,443,187 | 3364,510,1602,2023,187,195,2057,1993,855,210,937,75,146,104,443,444,2616,1263,2169,66,2104,668,475,1376,2691,1224 | -1.7278133504168929,0.8362984856412491,-0.09593126943002946,-0.3028748428550267,1.7820457887243357,1.72307457356377,-0.3190719005092798,-0.2867183612159623,0.38691633847751733,1.651602135580465,0.3138038545974289,2.546060857024669,2.0466941864597326,2.333576542930749,0.9705945223247175,0.9705945223247175,-0.583919668151991,0.1045887365929969,-0.36790863721425243,2.711259409326985,-0.33530974411801295,0.6014378848555904,0.9172078124078225,0.043549855895539176,-0.617805031632897,0.1348936174475735 | 3,417 |
Organophosphate ester transmembrane transporter activity | 9 | 14 | 2.212177 | 0.026954 | Q9HC21,Q9BSK2,P12235,O43808,O00400,Q9H2D1,Q8TB61,Q6NUK1,Q6KCM7 | Functions | GO Molecular function | msigdb_gomf | 228,3,365,236,16,176,86,474,222 | 16,2882,236,775,365,470,3072,222,474,86,770,3,176,228 | 3.5618203282976997,-0.7551608870541102,1.567220738704834,0.45921398013028775,1.1151934116250275,0.9172078124078225,-0.9132800387870509,1.6155716241957836,0.9172078124078225,2.4830307358799764,0.47357736156305924,4.079438950901208,1.8521189098662278,1.6035173065048012 | 3,417 |
Nucleotide transmembrane transporter activity | 9 | 14 | 2.212177 | 0.026954 | Q9HC21,Q9BSK2,P12235,O43808,O00400,Q9H2D1,Q8TB61,Q6NUK1,Q6KCM7 | Functions | GO Molecular function | msigdb_gomf | 228,3,365,236,16,176,86,474,222 | 16,2882,236,775,365,470,3072,222,474,86,770,3,176,228 | 3.5618203282976997,-0.7551608870541102,1.567220738704834,0.45921398013028775,1.1151934116250275,0.9172078124078225,-0.9132800387870509,1.6155716241957836,0.9172078124078225,2.4830307358799764,0.47357736156305924,4.079438950901208,1.8521189098662278,1.6035173065048012 | 3,417 |
Intrinsic component of golgi membrane | 6 | 11 | 2.21086 | 0.027046 | Q969X5,Q9Y282,L0R6Q1,Q8TB61,Q6ZRP7,O95070 | Localization | GO Cellular component | msigdb_gocc | 193,83,341,86,312,216 | 341,483,973,216,1213,984,2206,312,86,193,83 | 1.1927355777835806,0.8903495429355509,0.2843264501176428,1.6276038128114534,0.1348936174475735,0.2843264501176428,-0.3842701148909007,1.2820530290453684,2.4830307358799764,1.7349112933227129,2.504107696101658 | 3,417 |
Snap receptor activity | 8 | 17 | 2.205542 | 0.027416 | O95249,Q9P2W9,O60499,O14653,O43752,Q12981,O15400,Q9UEU0 | Functions | GO Molecular function | msigdb_gomf | 97,4,39,358,141,249,250,381 | 3142,358,250,758,141,39,1041,97,516,710,1789,249,1295,391,4,381,805 | -1.002837216956381,1.1281812332227774,1.5062759619135841,0.47357736156305924,2.0804411470022126,3.1166678348556403,0.23985743121252281,2.387342541189054,0.8227153339568873,0.5449214820360619,-0.19062001449545884,1.5185103694031445,0.08938291553650131,1.0629820996007722,4.079438950901208,1.0891399743619552,0.44481874473177313 | 3,417 |
Snare interactions in vesicular transport | 8 | 17 | 2.205542 | 0.027416 | O95249,Q9P2W9,O60499,O14653,O43752,Q12981,O15400,Q9UEU0 | Processes and pathways | KEGG Pathways | msigdb_kegg | 97,4,39,358,141,249,250,381 | 3142,358,250,758,141,39,1041,97,516,710,1789,249,1295,391,4,381,805 | -1.002837216956381,1.1281812332227774,1.5062759619135841,0.47357736156305924,2.0804411470022126,3.1166678348556403,0.23985743121252281,2.387342541189054,0.8227153339568873,0.5449214820360619,-0.19062001449545884,1.5185103694031445,0.08938291553650131,1.0629820996007722,4.079438950901208,1.0891399743619552,0.44481874473177313 | 3,417 |
Electron transport chain oxphos system in mitochondria | 21 | 52 | 2.193662 | 0.02826 | P00846,Q9Y6M9,P21912,O43676,P24539,O95299,P06576,P14406,O75964,O95168,P22695,P13073,O75880,P51970,P03886,O95139,Q7KZN9,P12236,O43674,P12235,P00403 | Processes and pathways | WikiPathways | msigdb_wp | 0,524,401,25,162,420,421,49,51,561,185,186,59,577,72,207,333,470,229,365,118 | 3295,1753,1379,229,25,1812,1858,748,839,1335,59,1605,51,207,561,3370,420,889,118,0,72,775,421,1955,1232,365,470,186,49,1898,1253,1928,3247,600,401,185,162,759,3280,2674,2192,1000,3201,3271,577,731,843,2759,1369,333,1037,524 | -1.3360226676213207,-0.17474182156354792,0.028199720326965952,1.5914407759518774,3.2777569763908665,-0.2065373586035809,-0.22249405275792178,0.48790903352268455,0.4014404547791768,0.05886364960372865,2.7620488324659895,-0.09593126943002946,2.902220138550719,1.651602135580465,0.7680975338781076,-1.8091450547166552,1.010349571326269,0.35777018045817044,2.191697356585309,4.079438950901208,2.598130352078956,0.45921398013028775,1.010349571326269,-0.27060224728382676,0.1197589134781991,1.1151934116250275,0.9172078124078225,1.7937767070377697,2.9417301538561795,-0.2384902973611259,0.1045887365929969,-0.25452629436448265,-1.2043820778052585,0.6991742787236601,1.0367189234918222,1.8054866977683843,1.932936974823011,0.47357736156305924,-1.2981337870876661,-0.617805031632897,-0.3842701148909007,0.2695373236736853,-1.1119839097372366,-1.2792732028995302,0.7406157866680001,0.5164778220540673,0.4014404547791768,-0.668970176567426,0.043549855895539176,1.2183796925819346,0.25471437049160844,0.8227153339568873 | 3,417 |
Retrograde transport endosome to golgi | 11 | 41 | 2.192946 | 0.028311 | O95249,O60749,Q8NBN3,O60499,Q93009,O43752,Q9Y5X3,O75503,Q9UEU0,Q4J6C6,Q9BVK6 | Processes and pathways | GO Biological process | msigdb_gobp | 97,99,166,39,329,141,397,315,381,322,352 | 2667,758,141,1279,1724,39,99,1894,315,97,1205,699,423,650,1067,2572,2644,1295,1321,1047,322,3103,3044,909,920,166,1741,329,2621,1450,352,557,1980,1085,1516,381,1087,2663,2880,1458,397 | -0.617805031632897,0.47357736156305924,2.0804411470022126,0.08938291553650131,-0.15890258245488978,3.1166678348556403,2.376624349071329,-0.2384902973611259,1.2693678996019138,2.387342541189054,0.1348936174475735,0.5590967396986621,1.010349571326269,0.6295128244024532,0.22496634533860416,-0.5670436789350108,-0.6008400388890252,0.08938291553650131,0.07414127779889645,0.23985743121252281,1.256658100316569,-0.9489529865692318,-0.8778043387082375,0.3431478364322099,0.32849244575329073,1.9099473684040134,-0.15890258245488978,1.2311640964910526,-0.583919668151991,-0.0026102883160087067,1.1669903758343456,0.7817950089963721,-0.27060224728382676,0.22496634533860416,-0.033567813428752,1.0891399743619552,0.22496634533860416,-0.6008400388890252,-0.7378300187664318,-0.0026102883160087067,1.0498637286274306 | 3,417 |
Ire1alpha activates chaperones | 8 | 26 | 2.188913 | 0.028603 | Q9Y5M8,Q9NWM8,O14653,O14773,O43731,P49748,P43307,O95070 | Processes and pathways | Reactome Pathways | msigdb_reactome | 64,196,358,206,110,439,26,216 | 358,206,110,1090,1554,216,502,2603,1180,26,439,1317,826,1644,1870,1347,1047,2680,940,2168,1544,196,1127,3268,2720,64 | 1.1281812332227774,1.651602135580465,2.2575598483675283,0.2100409512222278,-0.06467431361864844,1.6276038128114534,0.8498533620967631,-0.583919668151991,0.14999301851452415,3.2777569763908665,0.9705945223247175,0.07414127779889645,0.415932129064235,-0.11161663697128474,-0.22249405275792178,0.05886364960372865,0.23985743121252281,-0.617805031632897,0.3138038545974289,-0.36790863721425243,-0.049102349624348285,1.72307457356377,0.1950810860549713,-1.2604680723356168,-0.6348148888478948,2.7316219936973174 | 3,417 |
Sphingolipid metabolism | 10 | 14 | 2.180329 | 0.029233 | P04062,Q16880,Q13510,Q06136,Q16739,P16278,Q9NRA0,O95470,O15269,P06280 | Processes and pathways | KEGG Pathways | msigdb_kegg | 195,104,75,210,146,376,475,187,510,383 | 3364,510,1602,549,187,195,383,376,210,75,146,104,475,1376 | -1.7278133504168929,0.8362984856412491,-0.09593126943002946,0.7817950089963721,1.7820457887243357,1.72307457356377,1.0760741454068623,1.0891399743619552,1.651602135580465,2.546060857024669,2.0466941864597326,2.333576542930749,0.9172078124078225,0.043549855895539176 | 3,417 |
Inner mitochondrial membrane protein complex | 33 | 77 | 2.170613 | 0.02996 | P00846,Q9Y6M9,Q96CU9,Q16891,O60830,P21912,O43676,Q9NX63,Q9Y584,P24539,Q9P0J0,Q9Y5J7,Q8IYU8,O95299,P06576,P14406,O75964,Q99595,O95168,P22695,P62072,P13073,Q53H12,P51970,Q6UXV4,Q5XKP0,P03886,O14925,O95139,P12236,O43674,Q13505,P00403 | Localization | GO Cellular component | msigdb_gocc | 0,524,395,529,22,401,25,546,30,162,419,164,425,420,421,49,51,52,561,185,56,186,443,577,449,198,72,201,207,470,229,105,118 | 3295,1753,1379,201,229,25,22,1812,1858,748,1063,839,1335,1605,51,207,561,3370,420,889,118,0,72,421,1312,1955,1232,470,186,49,1898,1253,1928,3247,600,401,185,162,759,3280,2674,2192,1669,1000,3212,3201,3271,577,731,843,56,105,2759,1369,529,1101,443,1005,198,449,425,1877,395,768,52,724,835,1660,1154,546,419,1549,1273,695,30,164,524 | -1.3360226676213207,-0.17474182156354792,0.028199720326965952,1.6993368662863828,1.5914407759518774,3.2777569763908665,3.389160419925041,-0.2065373586035809,-0.22249405275792178,0.48790903352268455,0.22496634533860416,0.4014404547791768,0.05886364960372865,-0.09593126943002946,2.902220138550719,1.651602135580465,0.7680975338781076,-1.8091450547166552,1.010349571326269,0.35777018045817044,2.191697356585309,4.079438950901208,2.598130352078956,1.010349571326269,0.07414127779889645,-0.27060224728382676,0.1197589134781991,0.9172078124078225,1.7937767070377697,2.9417301538561795,-0.2384902973611259,0.1045887365929969,-0.25452629436448265,-1.2043820778052585,0.6991742787236601,1.0367189234918222,1.8054866977683843,1.932936974823011,0.47357736156305924,-1.2981337870876661,-0.617805031632897,-0.3842701148909007,-0.1273401837881595,0.2695373236736853,-1.1303571839723463,-1.1119839097372366,-1.2792732028995302,0.7406157866680001,0.5164778220540673,0.4014404547791768,2.7923363998378443,2.301105245667895,-0.668970176567426,0.043549855895539176,0.8091037855865696,0.2100409512222278,0.9705945223247175,0.2695373236736853,1.711216457757838,0.9572887845888515,1.010349571326269,-0.22249405275792178,1.0498637286274306,0.47357736156305924,2.8923057086966835,0.5307152226992892,0.415932129064235,-0.11161663697128474,0.180086585856304,0.7954637182819312,1.0235475745145948,-0.049102349624348285,0.1045887365929969,0.5732411343760665,3.221347085581454,1.9214522256714823,0.8227153339568873 | 3,417 |
Azurophil granule membrane | 14 | 26 | 2.157431 | 0.030972 | P07602,P42785,Q9NQX7,O95721,P10253,P51809,Q9NZJ7,P51148,Q6IAA8,Q8NF37,P27105,Q07065,Q92542,O95716 | Localization | GO Cellular component | msigdb_gocc | 32,385,138,516,170,710,335,716,660,720,244,87,351,479 | 2667,2222,2254,1811,479,516,32,2504,170,751,876,244,2754,385,716,710,87,660,720,351,2486,1034,138,928,335,1224 | -0.617805031632897,-0.4006732349357356,-0.41711821570494334,-0.2065373586035809,0.9037925174593933,0.8227153339568873,3.202436833742072,-0.5334238928726274,1.8753114211973756,0.48790903352268455,0.37235963057923405,1.5429108324741363,-0.668970176567426,1.0760741454068623,0.5307152226992892,0.5449214820360619,2.4618862687940686,0.6154905133855352,0.5307152226992892,1.1669903758343456,-0.5166796247488002,0.25471437049160844,2.1028433404883855,0.32849244575329073,1.2183796925819346,0.1348936174475735 | 3,417 |
Dilated cardiomyopathy | 18 | 41 | 2.150666 | 0.031503 | P00846,Q9H9S5,O95817,P03886,O43819,P12235,O95155,P06753,P53701,P36871,P42167,P42166,P23786,P09493,P49748,P00403,P02545,P16278 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,386,697,72,515,365,430,647,431,209,113,114,595,658,439,118,502,376 | 515,1858,430,1408,697,118,0,502,72,647,658,365,876,1992,3144,376,2331,595,2674,2675,209,1725,114,113,2261,439,431,3013,1434,2161,1873,3151,753,801,2523,2622,1541,1010,2246,2314,386 | 0.8227153339568873,-0.22249405275792178,0.9971248028613773,0.012813065246235574,0.5590967396986621,2.191697356585309,4.079438950901208,0.8498533620967631,2.598130352078956,0.6295128244024532,0.6154905133855352,1.1151934116250275,0.37235963057923405,-0.2867183612159623,-1.002837216956381,1.0891399743619552,-0.4501346415467144,0.7130174694629439,-0.617805031632897,-0.617805031632897,1.651602135580465,-0.15890258245488978,2.2356787664161804,2.2466283906528957,-0.41711821570494334,0.9705945223247175,0.9971248028613773,-0.860139758826078,-0.0026102883160087067,-0.36790863721425243,-0.22249405275792178,-1.002837216956381,0.48790903352268455,0.44481874473177313,-0.5334238928726274,-0.583919668151991,-0.049102349624348285,0.2695373236736853,-0.4006732349357356,-0.43360527729208703,1.0760741454068623 | 3,417 |
Organelle envelope lumen | 17 | 40 | 2.145403 | 0.031921 | Q9Y3B8,P07437,Q9H4A6,Q9Y5J7,Q8IYU8,Q9Y5L4,O60313,O14925,P05067,Q9Y5J9,O60220,Q16891,O95831,O00165,P62072,Q9NR28,Q53H12 | Localization | GO Cellular component | msigdb_gocc | 248,320,131,164,425,477,294,201,359,347,460,529,149,245,56,314,443 | 245,729,201,460,294,149,359,320,2185,1956,3010,3280,1181,1207,1641,577,1341,2573,56,2395,529,443,3074,3118,425,3252,1195,1149,3329,835,786,2558,131,1013,314,1016,248,164,347,477 | 1.5307219638457237,0.5164778220540673,1.6993368662863828,0.9305955446314544,1.3199613772518044,2.012773197487723,1.1281812332227774,1.256658100316569,-0.3842701148909007,-0.27060224728382676,-0.860139758826078,-1.2981337870876661,0.14999301851452415,0.1348936174475735,-0.11161663697128474,0.7406157866680001,0.05886364960372865,-0.5670436789350108,2.7923363998378443,-0.4833211743492699,0.8091037855865696,0.9705945223247175,-0.9132800387870509,-0.9668641351613078,1.010349571326269,-1.2043820778052585,0.14999301851452415,0.180086585856304,-1.451055899206297,0.415932129064235,0.45921398013028775,-0.5502118327072625,2.13630429417419,0.2695373236736853,1.2820530290453684,0.2695373236736853,1.5307219638457237,1.9214522256714823,1.1798756638524783,0.9172078124078225 | 3,417 |
Sphingolipid biosynthetic process | 10 | 21 | 2.144913 | 0.03196 | Q96G23,P04062,Q16880,Q13510,Q16739,Q06136,Q9NRA0,Q6Y1H2,Q53H12,O95470 | Processes and pathways | GO Biological process | msigdb_gobp | 66,195,104,75,146,210,475,444,443,187 | 3364,510,1602,187,195,2057,1993,855,210,937,75,146,104,443,444,66,668,475,1376,2691,1224 | -1.7278133504168929,0.8362984856412491,-0.09593126943002946,1.7820457887243357,1.72307457356377,-0.3190719005092798,-0.2867183612159623,0.38691633847751733,1.651602135580465,0.3138038545974289,2.546060857024669,2.0466941864597326,2.333576542930749,0.9705945223247175,0.9705945223247175,2.711259409326985,0.6014378848555904,0.9172078124078225,0.043549855895539176,-0.617805031632897,0.1348936174475735 | 3,417 |
SNARE protein | 8 | 14 | 2.142314 | 0.032168 | O95249,Q9P2W9,Q86Y82,O60499,O14653,O43752,O15400,Q9UEU0 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 97,4,391,39,358,141,250,381 | 3142,358,250,141,39,97,516,710,1789,1295,391,4,381,805 | -1.002837216956381,1.1281812332227774,1.5062759619135841,2.0804411470022126,3.1166678348556403,2.387342541189054,0.8227153339568873,0.5449214820360619,-0.19062001449545884,0.08938291553650131,1.0629820996007722,4.079438950901208,1.0891399743619552,0.44481874473177313 | 3,417 |
Protein targeting to membrane | 7 | 42 | 2.134416 | 0.032809 | Q15041,P46379,Q15629,P40855,O60725,Q9UL54,P43307 | Processes and pathways | GO Biological process | msigdb_gobp | 160,226,42,237,48,152,26 | 1306,1333,549,1551,48,2357,2603,1954,244,2844,760,2260,237,26,226,1385,917,1113,2702,1902,1259,2034,2478,1003,160,42,2206,1028,3381,834,1079,1627,2015,1513,2689,992,1663,1015,1804,152,694,1807 | 0.07414127779889645,0.05886364960372865,0.7817950089963721,-0.06467431361864844,2.9417301538561795,-0.46670653209308793,-0.583919668151991,-0.27060224728382676,1.5429108324741363,-0.7205457694435239,0.47357736156305924,-0.41711821570494334,1.567220738704834,3.2777569763908665,1.6035173065048012,0.028199720326965952,0.32849244575329073,0.1950810860549713,-0.6348148888478948,-0.2384902973611259,0.1045887365929969,-0.3028748428550267,-0.5166796247488002,0.2695373236736853,1.944401687938058,3.1070691737442258,-0.3842701148909007,0.25471437049160844,-2.0383196676442155,0.415932129064235,0.22496634533860416,-0.09593126943002946,-0.2867183612159623,-0.033567813428752,-0.617805031632897,0.2843264501176428,-0.11161663697128474,0.2695373236736853,-0.19062001449545884,1.9786763260210907,0.5732411343760665,-0.19062001449545884 | 3,417 |
SNARE protein | 8 | 15 | 2.12409 | 0.033663 | O95249,Q9P2W9,Q86Y82,O60499,O14653,O43752,O15400,Q9UEU0 | Functions | Panther Protein class | panther_protein_class | 97,4,391,39,358,141,250,381 | 3142,358,250,141,39,97,516,710,1789,1295,391,966,4,381,805 | -1.002837216956381,1.1281812332227774,1.5062759619135841,2.0804411470022126,3.1166678348556403,2.387342541189054,0.8227153339568873,0.5449214820360619,-0.19062001449545884,0.08938291553650131,1.0629820996007722,0.2990819080544139,4.079438950901208,1.0891399743619552,0.44481874473177313 | 3,417 |
Mitochondrial carrier protein [IPR002067] | 6 | 11 | 2.108725 | 0.034968 | Q9HC21,P12235,O43808,Q6NUK1,P12236,Q6KCM7 | Sequence | InterPro Family | interpro_family | 228,365,236,474,470,222 | 236,1429,775,365,470,879,222,474,506,228,1226 | 1.567220738704834,-0.0026102883160087067,0.45921398013028775,1.1151934116250275,0.9172078124078225,0.37235963057923405,1.6155716241957836,0.9172078124078225,0.8498533620967631,1.6035173065048012,0.1348936174475735 | 3,417 |
Inorganic anion transmembrane transporter activity | 11 | 23 | 2.096028 | 0.03608 | P21796,Q15043,Q02978,Q9C0H2,O43681,Q9Y277,Q9UBX3,P51798,Q96S66,P45880,Q9Y6M7 | Functions | GO Molecular function | msigdb_gomf | 69,326,456,202,549,76,109,403,346,60,646 | 2866,2882,549,900,824,69,60,779,639,403,1432,456,326,1164,846,346,1373,202,1488,109,76,3141,646 | -0.7378300187664318,-0.7551608870541102,0.7817950089963721,0.3431478364322099,0.415932129064235,2.63949253044833,2.751922092384719,0.45921398013028775,0.6435049519950851,1.0367189234918222,-0.0026102883160087067,0.9439558302360769,1.2439235324069875,0.165057285462392,0.4014404547791768,1.1927355777835806,0.043549855895539176,1.6993368662863828,-0.018070520659702844,2.2684732013809596,2.546060857024669,-0.9848254487759778,0.6435049519950851 | 3,417 |
Generalized myoclonic seizure | 10 | 41 | 2.086735 | 0.036912 | P00846,P07602,P04062,Q9Y619,Q7L7X3,P03886,Q13510,Q9NZJ7,P16278,Q96N66 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,32,195,36,165,72,75,335,376,313 | 1600,1988,1854,772,2023,0,72,195,32,376,401,2674,980,1900,3196,2756,812,2365,2892,2644,565,631,1823,2201,75,2204,2895,1219,165,1589,2169,2134,3316,313,506,1596,335,2936,1174,1273,36 | -0.09593126943002946,-0.2867183612159623,-0.22249405275792178,0.45921398013028775,-0.3028748428550267,4.079438950901208,2.598130352078956,1.72307457356377,3.202436833742072,1.0891399743619552,1.0367189234918222,-0.617805031632897,0.2843264501176428,-0.2384902973611259,-1.0936631895958675,-0.668970176567426,0.43039150987620567,-0.46670653209308793,-0.7551608870541102,-0.6008400388890252,0.7680975338781076,0.6574670293566639,-0.2065373586035809,-0.3842701148909007,2.546060857024669,-0.3842701148909007,-0.7551608870541102,0.1348936174475735,1.9099473684040134,-0.080283891168658,-0.36790863721425243,-0.3515885852686711,-1.3932804185781111,1.2820530290453684,0.8498533620967631,-0.080283891168658,1.2183796925819346,-0.7899635190956561,0.165057285462392,0.1045887365929969,3.1453808033753354 | 3,417 |
Spastic gait | 7 | 27 | 2.085146 | 0.037056 | Q15041,Q9Y619,Q15043,Q9NVI7,O00400,O75787,P25054 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 160,36,326,268,16,211,286 | 16,2328,211,1950,3225,1255,286,1045,1285,447,1613,2756,2119,1673,2201,619,160,326,1392,1299,2412,1302,2347,268,2386,2142,36 | 3.5618203282976997,-0.4501346415467144,1.6396139556611513,-0.27060224728382676,-1.1487833229977529,0.1045887365929969,1.3576511964696762,0.23985743121252281,0.08938291553650131,0.9572887845888515,-0.09593126943002946,-0.668970176567426,-0.3515885852686711,-0.1273401837881595,-0.3842701148909007,0.6713991887930522,1.944401687938058,1.2439235324069875,0.028199720326965952,0.08938291553650131,-0.4833211743492699,0.08938291553650131,-0.4501346415467144,1.457108438974517,-0.46670653209308793,-0.3515885852686711,3.1453808033753354 | 3,417 |
Insertion of tail anchored proteins into the endoplasmic reticulum membrane | 6 | 12 | 2.076541 | 0.037844 | P46379,P50402,P05067,P09601,O43681,P51648 | Processes and pathways | Reactome Pathways | msigdb_reactome | 226,257,359,11,549,24 | 549,1551,359,11,226,618,257,24,1113,2702,1295,1224 | 0.7817950089963721,-0.06467431361864844,1.1281812332227774,3.6154272920019888,1.6035173065048012,0.6713991887930522,1.481738356319479,3.3614840657953646,0.1950810860549713,-0.6348148888478948,0.08938291553650131,0.1348936174475735 | 3,417 |
Exercise intolerance | 8 | 33 | 2.074643 | 0.03802 | Q9Y2R0,Q8NI60,P03886,P12235,Q9H2D1,P36871,Q9NSD9,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 5,362,72,365,176,209,20,118 | 2944,118,3189,72,647,2535,365,876,1065,595,2908,2674,209,1725,762,3013,1473,443,1505,362,2765,2523,1541,3341,176,2314,20,1549,1017,5,2318,1776,1305 | -0.8074358076237756,2.191697356585309,-1.0936631895958675,2.598130352078956,0.6295128244024532,-0.5502118327072625,1.1151934116250275,0.37235963057923405,0.22496634533860416,0.7130174694629439,-0.7725386334031646,-0.617805031632897,1.651602135580465,-0.15890258245488978,0.47357736156305924,-0.860139758826078,-0.018070520659702844,0.9705945223247175,-0.033567813428752,1.1281812332227774,-0.668970176567426,-0.5334238928726274,-0.049102349624348285,-1.5093588210105136,1.8521189098662278,-0.43360527729208703,3.5168159185133003,-0.049102349624348285,0.2695373236736853,4.079438950901208,-0.43360527729208703,-0.17474182156354792,0.08938291553650131 | 3,417 |
Glycosphingolipid metabolic process | 6 | 11 | 2.073549 | 0.038121 | P04062,P17900,Q16880,Q16739,P16278,P06280 | Processes and pathways | GO Biological process | msigdb_gobp | 195,134,104,146,376,383 | 195,383,422,2184,376,134,828,937,146,104,668 | 1.72307457356377,1.0760741454068623,1.010349571326269,-0.3842701148909007,1.0891399743619552,2.1140159037622634,0.415932129064235,0.3138038545974289,2.0466941864597326,2.333576542930749,0.6014378848555904 | 3,417 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 9 | 34 | 2.066964 | 0.038738 | P61457,Q6UW02,P09601,P30519,Q15800,Q8NB78,O00767,Q16850,Q32P28 | Functions | GO Molecular function | msigdb_gomf | 324,172,11,13,304,239,332,58,321 | 1251,332,3364,972,2942,948,2808,914,794,1380,11,348,540,2991,13,324,1868,2442,782,304,58,321,2207,907,519,172,3315,1586,239,3001,3197,2457,1201,1664 | 0.1045887365929969,1.2183796925819346,-1.7278133504168929,0.2843264501176428,-0.8074358076237756,0.2990819080544139,-0.7033078821496582,0.32849244575329073,0.44481874473177313,0.028199720326965952,3.6154272920019888,1.1669903758343456,0.7954637182819312,-0.8425236583575074,3.579737287321298,1.2439235324069875,-0.22249405275792178,-0.4999787955465205,0.45921398013028775,1.2947135868342938,2.7721600981017382,1.256658100316569,-0.3842701148909007,0.3431478364322099,0.8227153339568873,1.8753114211973756,-1.3932804185781111,-0.080283891168658,1.567220738704834,-0.8425236583575074,-1.0936631895958675,-0.4999787955465205,0.14999301851452415,-0.11161663697128474 | 3,417 |
Intermediate filaments | 15 | 34 | 2.065824 | 0.038845 | P07197,P48681,Q99442,P07196,Q8WXH0,Q9Y496,Q16513,O75718,P08670,Q96K76,O60884,Q3SXM5,Q16352,Q9Y4J8,Q99471 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 288,701,834,233,753,727,845,78,144,115,773,85,473,807,667 | 773,2255,78,1635,2968,1862,1521,233,288,144,701,2889,842,2511,1261,1678,1647,473,845,85,3203,1103,753,1449,115,834,667,1354,3078,1513,2176,1661,727,807 | 0.45921398013028775,-0.41711821570494334,2.5251175908152326,-0.11161663697128474,-0.8249557647149923,-0.22249405275792178,-0.049102349624348285,1.5793419482693727,1.345112044634575,2.069211383415932,0.5590967396986621,-0.7551608870541102,0.4014404547791768,-0.5334238928726274,0.1045887365929969,-0.1273401837881595,-0.11161663697128474,0.9172078124078225,0.4014404547791768,2.493577626661402,-1.1119839097372366,0.2100409512222278,0.48790903352268455,-0.0026102883160087067,2.2247109135166085,0.415932129064235,0.6014378848555904,0.05886364960372865,-0.9132800387870509,-0.033567813428752,-0.36790863721425243,-0.11161663697128474,0.5307152226992892,0.44481874473177313 | 3,417 |
Peripheral demyelination | 6 | 16 | 2.065527 | 0.038873 | Q8TB36,P00846,P07602,P03886,P07196,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 480,0,32,72,233,335 | 549,0,72,233,32,2430,1580,1255,2507,1111,1293,480,1708,2765,335,1514 | 0.7817950089963721,4.079438950901208,2.598130352078956,1.5793419482693727,3.202436833742072,-0.4999787955465205,-0.080283891168658,0.1045887365929969,-0.5334238928726274,0.1950810860549713,0.08938291553650131,0.9037925174593933,-0.14310210131811343,-0.668970176567426,1.2183796925819346,-0.033567813428752 | 3,417 |
Assembly and cell surface presentation of nmda receptors | 11 | 13 | 2.065069 | 0.038916 | Q13555,Q13885,O14936,Q9BVA1,Q12959,P07196,Q9BUF5,Q9NUP9,Q14168,P68371,P04350 | Processes and pathways | Reactome Pathways | msigdb_reactome | 512,579,539,745,518,233,459,726,752,371,319 | 539,319,233,371,518,796,512,579,752,2271,459,745,726 | 0.7954637182819312,1.256658100316569,1.5793419482693727,1.1021796941094018,0.8227153339568873,0.44481874473177313,0.8362984856412491,0.7406157866680001,0.48790903352268455,-0.41711821570494334,0.9439558302360769,0.5022091395121904,0.5307152226992892 | 3,417 |
Delusions | 6 | 21 | 2.062864 | 0.039126 | P07602,Q9BQE5,P04062,Q9NZJ7,O60220,P21964 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,2,195,335,460,29 | 1575,549,460,195,32,1337,29,3164,1207,2230,878,1641,1004,2125,1707,1264,801,2,1374,335,1226 | -0.080283891168658,0.7817950089963721,0.9305955446314544,1.72307457356377,3.202436833742072,0.05886364960372865,3.221347085581454,-1.0390132878994311,0.1348936174475735,-0.4006732349357356,0.37235963057923405,-0.11161663697128474,0.2695373236736853,-0.3515885852686711,-0.14310210131811343,0.1045887365929969,0.44481874473177313,4.079438950901208,0.043549855895539176,1.2183796925819346,0.1348936174475735 | 3,417 |
Hand polydactyly | 10 | 38 | 2.061647 | 0.039241 | Q96J42,Q9UBM7,O43924,Q9Y263,Q10713,Q14739,Q15067,Q9UHX1,P21964,O95202 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 200,262,102,106,107,212,117,55,29,127 | 3032,1275,102,592,914,127,318,3279,29,2886,2846,2156,1615,629,107,619,1766,1261,2645,212,2896,117,1444,654,2826,2307,200,713,3137,1169,3230,2983,1545,262,55,623,3350,106 | -0.8778043387082375,0.08938291553650131,2.333576542930749,0.7130174694629439,0.32849244575329073,2.1474202525907056,1.256658100316569,-1.2981337870876661,3.221347085581454,-0.7551608870541102,-0.7205457694435239,-0.36790863721425243,-0.09593126943002946,0.6574670293566639,2.2902458390004905,0.6713991887930522,-0.17474182156354792,0.1045887365929969,-0.6008400388890252,1.6396139556611513,-0.7551608870541102,2.202720271552077,-0.0026102883160087067,0.6295128244024532,-0.7033078821496582,-0.43360527729208703,1.711216457757838,0.5449214820360619,-0.9848254487759778,0.165057285462392,-1.1487833229977529,-0.8249557647149923,-0.049102349624348285,1.4694349811947218,2.8224859993573723,0.6713991887930522,-1.5681991738536911,2.301105245667895 | 3,417 |
Golgi cisterna membrane | 11 | 22 | 2.060209 | 0.039379 | Q08379,Q9H4A6,Q10472,Q8NBN3,Q8WVQ1,Q10713,Q8NBZ7,Q15363,O00461,P51572,Q96JB2 | Localization | GO Cellular component | msigdb_gocc | 578,131,377,166,458,107,140,46,433,402,445 | 433,824,402,1213,3308,578,984,377,107,1824,46,166,140,1974,458,445,644,925,2138,131,1750,2495 | 0.9838731573525725,0.415932129064235,1.0367189234918222,0.1348936174475735,-1.3741374478355866,0.7406157866680001,0.2843264501176428,1.0891399743619552,2.2902458390004905,-0.2065373586035809,2.9810060001650047,1.9099473684040134,2.091651777071882,-0.27060224728382676,0.9439558302360769,0.9705945223247175,0.6435049519950851,0.32849244575329073,-0.3515885852686711,2.13630429417419,-0.15890258245488978,-0.5166796247488002 | 3,417 |
transporter | 15 | 63 | 2.05899 | 0.039495 | Q9Y619,Q15070,Q15012,Q9HD45,Q567V2,Q8N8Q8,Q9H2V7,Q9H2D1,Q8N1F7,Q99595,O60830,Q92973,P62072,Q8NFH4,Q9Y584 | Functions | Panther Protein class | panther_protein_class | 36,100,6,168,251,108,45,176,368,52,22,343,56,219,30 | 1061,1020,2465,913,1404,1754,971,496,549,1723,2054,22,2599,1360,1466,491,3072,2117,3302,1094,2155,2292,879,827,859,1290,1434,1259,56,1068,1069,2162,6,100,251,882,893,368,2979,108,219,1878,767,379,343,1683,689,723,52,668,770,3299,927,176,45,1713,168,588,2317,1016,30,793,36 | 0.22496634533860416,0.25471437049160844,-0.5166796247488002,0.32849244575329073,0.012813065246235574,-0.17474182156354792,0.2843264501176428,0.8633800839961283,0.7817950089963721,-0.15890258245488978,-0.3190719005092798,3.389160419925041,-0.583919668151991,0.043549855895539176,-0.018070520659702844,0.8768787712343713,-0.9132800387870509,-0.3515885852686711,-1.3550516474221492,0.2100409512222278,-0.36790863721425243,-0.43360527729208703,0.37235963057923405,0.415932129064235,0.38691633847751733,0.08938291553650131,-0.0026102883160087067,0.1045887365929969,2.7923363998378443,0.22496634533860416,0.22496634533860416,-0.36790863721425243,4.0711326084955255,2.3658887117772305,1.5062759619135841,0.37235963057923405,0.35777018045817044,1.1151934116250275,-0.8249557647149923,2.2684732013809596,1.6276038128114534,-0.22249405275792178,0.47357736156305924,1.0891399743619552,1.1927355777835806,-0.1273401837881595,0.5732411343760665,0.5307152226992892,2.8923057086966835,0.6014378848555904,0.47357736156305924,-1.3360226676213207,0.32849244575329073,1.8521189098662278,2.9907887060862692,-0.14310210131811343,1.9099473684040134,0.7268312627826058,-0.43360527729208703,0.2695373236736853,3.221347085581454,0.45921398013028775,3.1453808033753354 | 3,417 |
Hexosyltransferase activity | 19 | 37 | 2.05863 | 0.03953 | Q16739,P04843,Q6ZXV5,Q9BT22,P06865,P46976,Q13126,O60568,P04062,P06737,Q2TAA5,Q10469,Q10471,O75340,P46977,Q16880,Q10472,Q7Z4H8,Q96L58 | Functions | GO Molecular function | msigdb_gomf | 146,774,543,418,422,552,47,948,195,953,985,464,984,974,230,104,377,894,644 | 1251,3157,973,948,2023,974,195,774,1252,953,422,2184,2428,1065,1384,552,230,1868,1026,464,984,377,47,146,104,985,543,894,1350,2451,644,418,1712,1107,2589,2051,2079 | 0.1045887365929969,-1.0208997317821633,0.2843264501176428,0.2990819080544139,-0.3028748428550267,0.2843264501176428,1.72307457356377,0.45921398013028775,0.1045887365929969,0.2990819080544139,1.010349571326269,-0.3842701148909007,-0.4999787955465205,0.22496634533860416,0.028199720326965952,0.7817950089963721,1.5914407759518774,-0.22249405275792178,0.25471437049160844,0.9305955446314544,0.2843264501176428,1.0891399743619552,2.9613971697877646,2.0466941864597326,2.333576542930749,0.2843264501176428,0.7954637182819312,0.35777018045817044,0.05886364960372865,-0.4999787955465205,0.6435049519950851,1.0235475745145948,-0.14310210131811343,0.2100409512222278,-0.5670436789350108,-0.3028748428550267,-0.3190719005092798 | 3,417 |
Carbohydrate derivative transmembrane transporter activity | 7 | 11 | 2.046665 | 0.040691 | P12235,O43808,O00400,L0R6Q1,Q8TB61,Q6NUK1,Q6KCM7 | Functions | GO Molecular function | msigdb_gomf | 365,236,16,341,86,474,222 | 341,16,236,775,365,470,3072,222,474,86,770 | 1.1927355777835806,3.5618203282976997,1.567220738704834,0.45921398013028775,1.1151934116250275,0.9172078124078225,-0.9132800387870509,1.6155716241957836,0.9172078124078225,2.4830307358799764,0.47357736156305924 | 3,417 |
Membrane docking | 8 | 32 | 2.046638 | 0.040694 | P61026,Q86Y82,O60499,O43752,O15400,Q9UEU0,P16615,O95716 | Processes and pathways | GO Biological process | msigdb_gobp | 354,391,39,141,250,381,413,479 | 1666,2146,250,758,141,1577,1724,39,2150,2809,479,516,854,1638,413,1313,1130,1067,2541,3102,1643,354,1789,1295,1216,391,799,2713,1377,381,1015,805 | -0.1273401837881595,-0.36790863721425243,1.5062759619135841,0.47357736156305924,2.0804411470022126,-0.080283891168658,-0.15890258245488978,3.1166678348556403,-0.36790863721425243,-0.7033078821496582,0.9037925174593933,0.8227153339568873,0.38691633847751733,-0.11161663697128474,1.0235475745145948,0.07414127779889645,0.180086585856304,0.22496634533860416,-0.5502118327072625,-0.9489529865692318,-0.11161663697128474,1.1540796106437512,-0.19062001449545884,0.08938291553650131,0.1348936174475735,1.0629820996007722,0.44481874473177313,-0.6348148888478948,0.043549855895539176,1.0891399743619552,0.2695373236736853,0.44481874473177313 | 3,417 |
Abnormality of pulmonary circulation | 13 | 35 | 2.044594 | 0.040895 | Q6NUK1,P51970,P04062,Q14108,P03886,O75844,Q9NZ08,P22413,P02545,Q71SY5,P51798,P00403,Q06330 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 474,577,195,98,72,74,270,243,502,372,403,118,188 | 2696,74,1813,889,118,1280,502,72,195,954,600,3279,891,243,759,2062,2029,2606,403,577,188,98,3202,2954,1349,474,372,1192,1590,1879,2009,2415,270,3391,1574 | -0.6348148888478948,2.546060857024669,-0.2065373586035809,0.35777018045817044,2.191697356585309,0.08938291553650131,0.8498533620967631,2.598130352078956,1.72307457356377,0.2990819080544139,0.6991742787236601,-1.2981337870876661,0.35777018045817044,1.5429108324741363,0.47357736156305924,-0.3190719005092798,-0.3028748428550267,-0.583919668151991,1.0367189234918222,0.7406157866680001,1.7820457887243357,2.387342541189054,-1.1119839097372366,-0.8074358076237756,0.05886364960372865,0.9172078124078225,1.1021796941094018,0.14999301851452415,-0.080283891168658,-0.22249405275792178,-0.2867183612159623,-0.4833211743492699,1.4447586398473278,-2.3871559755332323,-0.06467431361864844 | 3,417 |
Organic acid transport | 21 | 46 | 2.044281 | 0.040926 | P31751,O95563,P14174,Q15041,Q9Y619,P30825,Q6P4A7,Q9Y3D6,Q9H2D1,P28288,P08183,P53985,Q8TDW0,Q02978,P23786,O60831,Q9UBX3,O43808,P53007,Q9H936,Q96NB2 | Processes and pathways | GO Biological process | msigdb_gobp | 760,656,28,160,36,40,171,694,176,570,323,827,846,456,595,232,109,236,879,506,769 | 2353,2882,1723,236,232,1429,2722,656,2289,3143,1409,952,2257,323,1231,28,891,595,570,2991,40,760,1132,3072,1431,879,827,1432,456,937,160,2237,2005,1970,171,846,769,2485,176,1303,506,1572,109,1226,694,36 | -0.46670653209308793,-0.7551608870541102,-0.15890258245488978,1.567220738704834,1.5793419482693727,-0.0026102883160087067,-0.651869854997686,0.6154905133855352,-0.43360527729208703,-1.002837216956381,0.012813065246235574,0.2990819080544139,-0.41711821570494334,1.2439235324069875,0.1197589134781991,3.221347085581454,0.35777018045817044,0.7130174694629439,0.7543711682631408,-0.8425236583575074,3.1070691737442258,0.47357736156305924,0.180086585856304,-0.9132800387870509,-0.0026102883160087067,0.37235963057923405,0.415932129064235,-0.0026102883160087067,0.9439558302360769,0.3138038545974289,1.944401687938058,-0.4006732349357356,-0.2867183612159623,-0.27060224728382676,1.8753114211973756,0.4014404547791768,0.47357736156305924,-0.5166796247488002,1.8521189098662278,0.08938291553650131,0.8498533620967631,-0.06467431361864844,2.2684732013809596,0.1348936174475735,0.5732411343760665,3.1453808033753354 | 3,417 |
oxidase | 7 | 17 | 2.041629 | 0.041188 | O43819,Q8NB78,Q15800,P14406,Q6ZRP7,P13073,O75880 | Functions | Panther Protein class | panther_protein_class | 515,239,304,49,312,186,59 | 1379,515,2942,914,59,1232,186,49,1253,600,1207,1641,304,1052,312,239,1014 | 0.028199720326965952,0.8227153339568873,-0.8074358076237756,0.32849244575329073,2.7620488324659895,0.1197589134781991,1.7937767070377697,2.9417301538561795,0.1045887365929969,0.6991742787236601,0.1348936174475735,-0.11161663697128474,1.2947135868342938,0.23985743121252281,1.2820530290453684,1.567220738704834,0.2695373236736853 | 3,417 |
Hallucinations | 10 | 47 | 2.039835 | 0.041367 | P07602,P50897,Q9BQE5,P04062,Q6DKK2,O60313,P05067,Q9NZJ7,O75503,P21964 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,1,2,195,136,294,359,335,315,29 | 3101,1600,730,1575,549,294,1811,315,1090,1177,195,359,32,1337,1410,3059,1958,29,384,1207,2230,1818,1641,1,812,2263,1673,1761,2336,3407,1439,1499,3216,136,2239,986,1392,1504,1450,3329,2,2215,335,1517,1226,1549,2142 | -0.9489529865692318,-0.09593126943002946,0.5164778220540673,-0.080283891168658,0.7817950089963721,1.3199613772518044,-0.2065373586035809,1.2693678996019138,0.2100409512222278,0.14999301851452415,1.72307457356377,1.1281812332227774,3.202436833742072,0.05886364960372865,0.012813065246235574,-0.8955176729308301,-0.27060224728382676,3.221347085581454,1.0760741454068623,0.1348936174475735,-0.4006732349357356,-0.2065373586035809,-0.11161663697128474,4.079438950901208,0.43039150987620567,-0.41711821570494334,-0.1273401837881595,-0.17474182156354792,-0.4501346415467144,-3.4328968129874733,-0.0026102883160087067,-0.033567813428752,-1.1303571839723463,2.1028433404883855,-0.4006732349357356,0.2843264501176428,0.028199720326965952,-0.033567813428752,-0.0026102883160087067,-1.451055899206297,4.079438950901208,-0.3842701148909007,1.2183796925819346,-0.033567813428752,0.1348936174475735,-0.049102349624348285,-0.3515885852686711 | 3,417 |
Abnormal enchondral ossification | 13 | 31 | 2.039251 | 0.041425 | O96028,Q96HY6,P08236,Q9Y619,Q9UBM7,Q9UG56,Q8WVQ1,P40855,O00116,P38435,P22413,Q14739,O95202 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 318,129,289,36,262,622,458,237,489,337,243,212,127 | 489,3255,749,127,2839,318,289,1777,3279,243,1994,337,237,917,1902,2645,212,2927,1100,1119,1874,1444,458,129,644,2139,262,622,3350,2630,36 | 0.8768787712343713,-1.2230228392271356,0.48790903352268455,2.1474202525907056,-0.7205457694435239,1.256658100316569,1.345112044634575,-0.19062001449545884,-1.2981337870876661,1.5429108324741363,-0.2867183612159623,1.2055702200831364,1.567220738704834,0.32849244575329073,-0.2384902973611259,-0.6008400388890252,1.6396139556611513,-0.7899635190956561,0.2100409512222278,0.1950810860549713,-0.22249405275792178,-0.0026102883160087067,0.9439558302360769,2.1474202525907056,0.6435049519950851,-0.3515885852686711,1.4694349811947218,0.6713991887930522,-1.5681991738536911,-0.583919668151991,3.1453808033753354 | 3,417 |
Elevated pulmonary artery pressure | 12 | 30 | 2.032209 | 0.042132 | Q6NUK1,P51970,P04062,Q14108,P03886,O75844,P22413,P02545,Q71SY5,P51798,P00403,Q06330 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 474,577,195,98,72,74,243,502,372,403,118,188 | 2696,74,889,118,1280,502,72,195,954,600,3279,891,243,759,2062,2606,403,577,188,98,2954,1349,474,372,1192,1879,2009,2415,3391,1574 | -0.6348148888478948,2.546060857024669,0.35777018045817044,2.191697356585309,0.08938291553650131,0.8498533620967631,2.598130352078956,1.72307457356377,0.2990819080544139,0.6991742787236601,-1.2981337870876661,0.35777018045817044,1.5429108324741363,0.47357736156305924,-0.3190719005092798,-0.583919668151991,1.0367189234918222,0.7406157866680001,1.7820457887243357,2.387342541189054,-0.8074358076237756,0.05886364960372865,0.9172078124078225,1.1021796941094018,0.14999301851452415,-0.22249405275792178,-0.2867183612159623,-0.4833211743492699,-2.3871559755332323,-0.06467431361864844 | 3,417 |
ER-Golgi transport | 25 | 57 | 2.030059 | 0.042351 | Q9P2W9,Q969M3,P49257,Q96RQ1,P48444,P51572,P84085,P61019,O95197,Q9NR31,P24390,Q15363,P49755,Q9UHQ4,P20340,P18085,Q969X5,Q6NUQ1,Q9Y282,O95070,O95249,P49069,O43731,Q12981,O15498 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 4,521,650,276,777,402,780,541,37,560,44,46,440,708,699,698,193,586,83,216,97,618,110,249,758 | 994,933,758,2253,1277,110,2150,1041,1554,216,37,97,1951,3383,698,699,44,1781,777,618,650,440,402,2949,2088,2846,2031,541,1095,860,780,249,2707,46,1390,919,1190,586,1910,883,2375,940,1974,1913,521,193,276,1483,1544,560,4,2020,708,83,2494,806,2022 | 0.2695373236736853,0.3138038545974289,0.47357736156305924,-0.41711821570494334,0.08938291553650131,2.2575598483675283,-0.36790863721425243,0.23985743121252281,-0.06467431361864844,1.6276038128114534,3.1262526328104014,2.387342541189054,-0.27060224728382676,-2.102282743065307,0.5590967396986621,0.5590967396986621,3.000556997593149,-0.19062001449545884,0.45921398013028775,0.6713991887930522,0.6295128244024532,0.9705945223247175,1.0367189234918222,-0.8074358076237756,-0.33530974411801295,-0.7205457694435239,-0.3028748428550267,0.7954637182819312,0.2100409512222278,0.38691633847751733,0.45921398013028775,1.5185103694031445,-0.6348148888478948,2.9810060001650047,0.028199720326965952,0.32849244575329073,0.14999301851452415,0.7268312627826058,-0.2384902973611259,0.37235963057923405,-0.46670653209308793,0.3138038545974289,-0.27060224728382676,-0.2384902973611259,0.8227153339568873,1.7349112933227129,1.4199889089821724,-0.018070520659702844,-0.049102349624348285,0.7817950089963721,4.079438950901208,-0.2867183612159623,0.5590967396986621,2.504107696101658,-0.5166796247488002,0.44481874473177313,-0.2867183612159623 | 3,417 |
Carbohydrate derivative catabolic process | 16 | 37 | 2.025333 | 0.042833 | P08236,P07711,P04062,P17900,Q9NUJ1,P54802,P06865,P35610,O60502,Q13126,P33908,Q9H773,P16278,P13051,P00813,P06280 | Processes and pathways | GO Biological process | msigdb_gobp | 289,119,195,134,231,103,422,617,174,47,551,370,376,626,27,383 | 2352,174,2782,2565,27,195,1310,383,422,2184,119,289,626,915,376,134,3256,3200,551,617,3410,1929,1317,1613,2364,103,1260,47,1328,1449,2657,661,3025,370,231,1852,1946 | -0.46670653209308793,1.8521189098662278,-0.6861161020861396,-0.5670436789350108,3.240203652278563,1.72307457356377,0.07414127779889645,1.0760741454068623,1.010349571326269,-0.3842701148909007,2.191697356585309,1.345112044634575,0.6574670293566639,0.32849244575329073,1.0891399743619552,2.1140159037622634,-1.2230228392271356,-1.1119839097372366,0.7817950089963721,0.6713991887930522,-4.2212385463434146,-0.25452629436448265,0.07414127779889645,-0.09593126943002946,-0.46670653209308793,2.333576542930749,0.1045887365929969,2.9613971697877646,0.07414127779889645,-0.0026102883160087067,-0.6008400388890252,0.6154905133855352,-0.860139758826078,1.1151934116250275,1.5914407759518774,-0.2065373586035809,-0.25452629436448265 | 3,417 |
Tubulin, conserved site [IPR017975] | 6 | 7 | 2.020636 | 0.043317 | Q13885,P07437,Q9BVA1,Q9BUF5,P68371,P04350 | Sequence | InterPro Conserved site | interpro_conserved_site | 579,320,745,459,371,319 | 319,320,371,796,579,459,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,0.5022091395121904 | 3,417 |
Beta tubulin, autoregulation binding site [IPR013838] | 6 | 7 | 2.020636 | 0.043317 | Q13885,P07437,Q9BVA1,Q9BUF5,P68371,P04350 | Sequence | InterPro Binding site | interpro_binding_site | 579,320,745,459,371,319 | 319,320,371,796,579,459,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,0.5022091395121904 | 3,417 |
Tubulin/FtsZ, GTPase domain [IPR003008] | 6 | 7 | 2.020636 | 0.043317 | Q13885,P07437,Q9BVA1,Q9BUF5,P68371,P04350 | Sequence | InterPro Domain | interpro_domain | 579,320,745,459,371,319 | 319,320,371,796,579,459,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,0.5022091395121904 | 3,417 |
tubulin | 6 | 7 | 2.020636 | 0.043317 | Q13885,P07437,Q9BVA1,Q9BUF5,P68371,P04350 | Functions | Panther Protein class | panther_protein_class | 579,320,745,459,371,319 | 319,320,371,796,579,459,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,0.5022091395121904 | 3,417 |
Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] | 6 | 7 | 2.020636 | 0.043317 | Q13885,P07437,Q9BVA1,Q9BUF5,P68371,P04350 | Sequence | InterPro Domain | interpro_domain | 579,320,745,459,371,319 | 319,320,371,796,579,459,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,0.5022091395121904 | 3,417 |
Beta tubulin [IPR002453] | 6 | 7 | 2.020636 | 0.043317 | Q13885,P07437,Q9BVA1,Q9BUF5,P68371,P04350 | Sequence | InterPro Family | interpro_family | 579,320,745,459,371,319 | 319,320,371,796,579,459,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,0.5022091395121904 | 3,417 |
Tubulin [IPR000217] | 6 | 7 | 2.020636 | 0.043317 | Q13885,P07437,Q9BVA1,Q9BUF5,P68371,P04350 | Sequence | InterPro Family | interpro_family | 579,320,745,459,371,319 | 319,320,371,796,579,459,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,0.5022091395121904 | 3,417 |
Tubulin | 6 | 7 | 2.020636 | 0.043317 | Q13885,P07437,Q9BVA1,Q9BUF5,P68371,P04350 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 579,320,745,459,371,319 | 319,320,371,796,579,459,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,0.5022091395121904 | 3,417 |
Tubulin, C-terminal [IPR023123] | 6 | 7 | 2.020636 | 0.043317 | Q13885,P07437,Q9BVA1,Q9BUF5,P68371,P04350 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 579,320,745,459,371,319 | 319,320,371,796,579,459,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,0.5022091395121904 | 3,417 |
Tubulin/FtsZ, C-terminal [IPR008280] | 6 | 7 | 2.020636 | 0.043317 | Q13885,P07437,Q9BVA1,Q9BUF5,P68371,P04350 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 579,320,745,459,371,319 | 319,320,371,796,579,459,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,0.5022091395121904 | 3,417 |
Tubulin/FtsZ-like, C-terminal domain [IPR037103] | 6 | 7 | 2.020636 | 0.043317 | Q13885,P07437,Q9BVA1,Q9BUF5,P68371,P04350 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 579,320,745,459,371,319 | 319,320,371,796,579,459,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,0.5022091395121904 | 3,417 |
Molecular carrier activity | 16 | 38 | 2.008105 | 0.044632 | O95817,Q9Y5J7,Q9Y5L0,Q15070,O43819,Q96P70,Q8N4V1,Q9UI26,Q8N8Q8,P40855,Q5J8M3,Q92973,P62072,Q9NPA0,O75880,Q8TEX9 | Functions | GO Molecular function | msigdb_gomf | 697,164,793,100,515,689,14,588,108,237,659,343,56,220,59,767 | 1020,2465,913,1754,1853,1040,515,2054,59,697,840,2427,1466,237,1094,2155,1290,56,1531,2162,816,100,659,14,2376,108,767,343,689,3329,927,1713,220,3386,588,2317,164,793 | 0.25471437049160844,-0.5166796247488002,0.32849244575329073,-0.17474182156354792,-0.22249405275792178,0.23985743121252281,0.8227153339568873,-0.3190719005092798,2.7620488324659895,0.5590967396986621,0.4014404547791768,-0.4999787955465205,-0.018070520659702844,1.567220738704834,0.2100409512222278,-0.36790863721425243,0.08938291553650131,2.7923363998378443,-0.049102349624348285,-0.36790863721425243,0.43039150987620567,2.3658887117772305,0.6154905133855352,3.5707848317991115,-0.46670653209308793,2.2684732013809596,0.47357736156305924,1.1927355777835806,0.5732411343760665,-1.451055899206297,0.32849244575329073,-0.14310210131811343,1.6276038128114534,-2.2103407897809766,0.7268312627826058,-0.43360527729208703,1.9214522256714823,0.45921398013028775 | 3,417 |
Intestinal malrotation | 8 | 33 | 2.004411 | 0.045026 | O96028,Q9UBM7,Q8NCH0,Q15392,Q9NSD9,Q14739,P21964,O95202 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 318,262,50,147,20,212,29,127 | 3032,2883,592,3034,1062,3255,127,318,3279,29,1560,2510,2846,1615,1432,1999,2439,619,2645,2895,212,147,2649,2274,50,1444,2826,2307,713,20,262,374,2021 | -0.8778043387082375,-0.7551608870541102,0.7130174694629439,-0.8778043387082375,0.22496634533860416,-1.2230228392271356,2.1474202525907056,1.256658100316569,-1.2981337870876661,3.221347085581454,-0.06467431361864844,-0.5334238928726274,-0.7205457694435239,-0.09593126943002946,-0.0026102883160087067,-0.2867183612159623,-0.4999787955465205,0.6713991887930522,-0.6008400388890252,-0.7551608870541102,1.6396139556611513,2.024099644140111,-0.6008400388890252,-0.41711821570494334,2.9417301538561795,-0.0026102883160087067,-0.7033078821496582,-0.43360527729208703,0.5449214820360619,3.5168159185133003,1.4694349811947218,1.1021796941094018,-0.2867183612159623 | 3,417 |
Serine hydrolase activity | 9 | 19 | 2.002411 | 0.045241 | P42785,P10619,P67812,Q9H3G5,O14773,Q16740,Q9HB40,Q4J6C6,Q6NTF9 | Functions | GO Molecular function | msigdb_gomf | 385,388,41,235,206,528,54,322,223 | 206,950,388,3058,2538,1994,385,2362,2292,527,41,528,1120,322,1479,223,2582,235,54 | 1.651602135580465,0.2990819080544139,1.0629820996007722,-0.8955176729308301,-0.5502118327072625,-0.2867183612159623,1.0760741454068623,-0.46670653209308793,-0.43360527729208703,0.8091037855865696,3.1070691737442258,0.8091037855865696,0.1950810860549713,1.256658100316569,-0.018070520659702844,1.6155716241957836,-0.5670436789350108,1.5793419482693727,2.862473067400689 | 3,417 |
Proton transmembrane transport | 18 | 44 | 1.999728 | 0.04553 | P00846,P24539,P25705,P56134,P05023,P06576,P12235,Q7KZN9,O00400,Q99623,O75964,P05141,Q9H936,Q13423,P00403,Q9NRA0,P13073,P20674 | Processes and pathways | GO Biological process | msigdb_gobp | 0,162,759,731,511,421,365,333,16,724,51,775,506,151,118,475,186,600 | 16,1753,1379,2353,1278,1812,1605,51,118,0,511,775,421,1312,1232,365,186,1928,600,2471,3286,162,759,2843,2192,1000,979,2924,3201,779,731,843,1644,904,151,333,3329,724,1302,506,475,1015,1457,1016 | 3.5618203282976997,-0.17474182156354792,0.028199720326965952,-0.46670653209308793,0.08938291553650131,-0.2065373586035809,-0.09593126943002946,2.902220138550719,2.191697356585309,4.079438950901208,0.8362984856412491,0.45921398013028775,1.010349571326269,0.07414127779889645,0.1197589134781991,1.1151934116250275,1.7937767070377697,-0.25452629436448265,0.6991742787236601,-0.5166796247488002,-1.3170501619437505,1.932936974823011,0.47357736156305924,-0.7205457694435239,-0.3842701148909007,0.2695373236736853,0.2843264501176428,-0.7899635190956561,-1.1119839097372366,0.45921398013028775,0.5164778220540673,0.4014404547791768,-0.11161663697128474,0.3431478364322099,1.9786763260210907,1.2183796925819346,-1.451055899206297,0.5307152226992892,0.08938291553650131,0.8498533620967631,0.9172078124078225,0.2695373236736853,-0.0026102883160087067,0.2695373236736853 | 3,417 |
Ion transmembrane transporter activity | 47 | 108 | 1.994984 | 0.046045 | P00846,Q9NVV0,P51797,Q93050,P35670,P05023,Q8N4V1,Q70HW3,O00400,Q9HD20,Q9Y487,Q13423,P51798,P16615,Q9HC07,P24539,Q9Y619,P30825,O43681,Q6P4A7,P06576,Q9H2D1,O75964,P13073,P45880,P21796,Q15043,Q02978,Q9C0H2,Q9Y277,Q7KZN9,Q8TB61,Q6NUK1,Q96S66,P12236,Q6KCM7,P20674,Q9HC21,Q6P4Q7,Q9UM00,Q9UBX3,P12235,O43808,Q9H936,P00403,Q9Y6M7,O95202 | Functions | GO Molecular function | msigdb_gomf | 0,645,639,135,394,511,14,142,16,145,274,151,403,413,31,162,36,40,549,171,421,176,51,186,60,69,326,456,202,76,333,86,474,346,470,222,600,228,487,623,109,365,236,506,118,646,127 | 2866,16,1379,2353,2882,549,1723,236,1429,1605,51,127,656,118,0,900,511,2224,775,421,2503,2426,1231,1312,824,1232,365,470,186,413,1928,1559,600,2471,3286,69,1780,162,759,40,2192,394,1000,979,2924,3072,60,3201,779,639,403,879,827,1432,731,843,1644,1259,1213,904,2034,456,151,1584,326,2005,1164,222,474,1970,171,487,882,142,333,14,1877,86,846,1880,135,1054,769,346,770,1078,1373,202,1034,176,1303,506,1572,31,228,145,645,1488,109,1457,1226,623,76,274,738,36,3141,646 | -0.7378300187664318,3.5618203282976997,0.028199720326965952,-0.46670653209308793,-0.7551608870541102,0.7817950089963721,-0.15890258245488978,1.567220738704834,-0.0026102883160087067,-0.09593126943002946,2.902220138550719,2.1474202525907056,0.6154905133855352,2.191697356585309,4.079438950901208,0.3431478364322099,0.8362984856412491,-0.4006732349357356,0.45921398013028775,1.010349571326269,-0.5334238928726274,-0.4999787955465205,0.1197589134781991,0.07414127779889645,0.415932129064235,0.1197589134781991,1.1151934116250275,0.9172078124078225,1.7937767070377697,1.0235475745145948,-0.25452629436448265,-0.06467431361864844,0.6991742787236601,-0.5166796247488002,-1.3170501619437505,2.63949253044833,-0.19062001449545884,1.932936974823011,0.47357736156305924,3.1070691737442258,-0.3842701148909007,1.0498637286274306,0.2695373236736853,0.2843264501176428,-0.7899635190956561,-0.9132800387870509,2.751922092384719,-1.1119839097372366,0.45921398013028775,0.6435049519950851,1.0367189234918222,0.37235963057923405,0.415932129064235,-0.0026102883160087067,0.5164778220540673,0.4014404547791768,-0.11161663697128474,0.1045887365929969,0.1348936174475735,0.3431478364322099,-0.3028748428550267,0.9439558302360769,1.9786763260210907,-0.080283891168658,1.2439235324069875,-0.2867183612159623,0.165057285462392,1.6155716241957836,0.9172078124078225,-0.27060224728382676,1.8753114211973756,0.8903495429355509,0.37235963057923405,2.0804411470022126,1.2183796925819346,3.5707848317991115,-0.22249405275792178,2.4830307358799764,0.4014404547791768,-0.22249405275792178,2.1140159037622634,0.23985743121252281,0.47357736156305924,1.1927355777835806,0.47357736156305924,0.22496634533860416,0.043549855895539176,1.6993368662863828,0.25471437049160844,1.8521189098662278,0.08938291553650131,0.8498533620967631,-0.06467431361864844,3.2118986899262745,1.6035173065048012,2.0579624190940984,0.6435049519950851,-0.018070520659702844,2.2684732013809596,-0.0026102883160087067,0.1348936174475735,0.6713991887930522,2.546060857024669,1.4323854934737215,0.5164778220540673,3.1453808033753354,-0.9848254487759778,0.6435049519950851 | 3,417 |
Neuronal loss in central nervous system | 6 | 12 | 1.99482 | 0.046062 | P07602,P35637,P04062,Q9NZJ7,Q9BTW9,O15118 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,384,195,335,214,148 | 148,515,2809,195,32,2059,384,2230,1219,214,335,1687 | 2.012773197487723,0.8227153339568873,-0.7033078821496582,1.72307457356377,3.202436833742072,-0.3190719005092798,1.0760741454068623,-0.4006732349357356,0.1348936174475735,1.6396139556611513,1.2183796925819346,-0.1273401837881595 | 3,417 |
Tubulin/FtsZ, GTPase domain superfamily [IPR036525] | 6 | 8 | 1.982095 | 0.047469 | P07437,Q13885,Q9BVA1,Q9BUF5,P68371,P04350 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 320,579,745,459,371,319 | 319,320,371,796,579,459,1626,745 | 1.256658100316569,1.256658100316569,1.1021796941094018,0.44481874473177313,0.7406157866680001,0.9439558302360769,-0.09593126943002946,0.5022091395121904 | 3,417 |
Thoracic hypoplasia | 13 | 31 | 1.980992 | 0.047592 | Q96HY6,P16435,P04062,P42345,Q9UM00,Q8WVQ1,P06753,O75718,Q9UHX1,Q14739,P51798,P02545,Q96A33 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,540,195,562,623,458,647,78,55,212,403,502,284 | 2721,3255,78,502,195,647,540,3279,1694,1467,562,2435,2118,403,1902,3215,212,1390,1100,1874,1444,2408,458,284,129,713,2215,55,623,2141,2630 | -0.651869854997686,-1.2230228392271356,2.5251175908152326,0.8498533620967631,1.72307457356377,0.6295128244024532,0.7954637182819312,-1.2981337870876661,-0.14310210131811343,-0.018070520659702844,0.7680975338781076,-0.4999787955465205,-0.3515885852686711,1.0367189234918222,-0.2384902973611259,-1.1303571839723463,1.6396139556611513,0.028199720326965952,0.2100409512222278,-0.22249405275792178,-0.0026102883160087067,-0.4833211743492699,0.9439558302360769,1.382657610013963,2.1474202525907056,0.5449214820360619,-0.3842701148909007,2.8224859993573723,0.6713991887930522,-0.3515885852686711,-0.583919668151991 | 3,417 |
Mitochondrial envelope | 137 | 323 | 5.642112 | 0 | Q9Y3D6,O43772,P12235,O75880,Q9HCL2,P30405,O43819,Q9NZ45,O43674,P14406,Q9H2V7,P21912,Q9NPL8,Q9P0M9,Q567V2,Q9HC21,P82663,Q9H3K2,P24539,Q8IWA4,O95202,Q99536,Q92667,Q9Y619,O95139,P82675,O96000,P09001,O75380,Q9H4A6,Q9BRJ2,P17152,Q7KZN9,Q8TB36,Q07820,Q9P0S9,P62072,P36404,Q9Y277,Q9NUQ2,Q9BYD2,Q9UBX3,Q16795,Q5HYK3,Q5VT66,Q9BUK6,P22570,O15121,P55061,Q9Y2Q9,Q96TA2,P82912,Q9BYT8,Q8NAN2,P49406,Q6P1L8,Q9Y2R5,Q9Y6C9,Q8IXI1,Q9UJS0,Q5HYI7,Q96BW9,Q12981,P23786,P82914,Q92552,Q07812,Q9BT17,Q96IX5,P08574,O75306,Q96NB2,Q8N983,P31040,Q02218,Q9H078,Q14318,O00483,Q9NVH1,P10606,O43615,O75431,P03886,Q9NX20,O75616,Q9NYK5,Q6KCM7,Q9NQG6,Q5T9A4,P31930,Q9BWH2,O95831,O75746,Q9Y6M9,Q15070,Q02978,P57105,Q6UXV4,Q9BYD1,Q13057,Q9H061,Q9BZE1,Q7Z2W9,Q9Y320,P53007,Q96HS1,P11310,Q32NB8,O75964,Q9H2D1,P40939,O95674,Q9P015,O95140,Q8IXI2,Q9UH62,Q9H936,Q96AY3,Q9GZY8,O95182,O95168,Q9NRA0,Q9BQ95,Q9NP92,Q8NBN7,Q9NZJ7,Q96DV4,Q8N5K1,Q14197,O43169,P05141,Q9NQZ5,Q9Y5J7,P12236,Q9HD33,P09543,O15235 | Localization | GO Cellular component | msigdb_gocc | 528,7,507,11,12,509,505,553,26,31,32,535,35,36,37,39,539,45,46,573,558,66,591,74,78,586,80,580,82,89,615,85,612,94,96,101,104,605,107,637,634,116,114,122,123,124,622,620,126,653,651,131,132,647,642,674,154,155,675,683,161,162,160,159,173,703,180,707,182,690,184,201,200,693,695,733,728,205,737,716,714,715,212,225,222,248,245,254,251,249,264,259,258,279,271,270,268,286,287,283,299,298,295,334,330,343,339,352,346,370,360,358,384,373,393,416,414,410,412,403,402,434,431,433,425,464,461,459,455,449,452,483,486,470,503,492,490 | 3268,1707,2647,1332,205,3384,2842,3322,2738,2793,620,2822,490,991,449,714,26,1822,7,505,3182,2844,956,2289,2823,1031,184,3240,82,715,746,1951,925,222,258,11,3020,346,958,2036,78,373,402,403,558,3062,1334,2436,358,259,80,1571,889,1071,3179,212,890,452,1904,1428,2743,690,580,492,3354,2973,3184,716,1954,1994,339,507,470,1574,1253,31,3006,717,85,959,2585,2654,2586,1430,1526,1869,2364,535,622,786,3315,2212,159,46,2954,1768,509,1830,693,249,1874,1165,1341,605,1769,1488,2089,360,815,2797,3333,1256,642,1534,2045,1082,1491,755,1537,1129,1581,1436,330,3042,1677,858,126,1220,1727,2548,268,104,2370,539,2977,586,131,173,762,1343,1087,1223,695,270,180,96,2932,1500,160,283,2774,2301,3011,2556,455,728,271,2006,971,2666,2415,1780,114,2100,352,972,2523,37,161,122,251,3105,123,2559,3311,2451,2560,245,3136,674,1924,286,974,3190,612,295,1046,1971,573,675,393,2013,2346,2275,1317,459,2698,200,647,425,1135,1102,1136,94,1455,1891,2781,703,2105,591,1405,2700,410,1139,162,2349,461,1279,3364,1457,1321,343,182,201,1552,651,1407,2063,66,3084,1145,3328,431,615,707,831,1057,124,3401,264,1059,2019,3223,287,634,1601,132,298,412,299,733,370,32,985,45,89,1021,414,1463,1513,1805,1150,2157,39,12,503,1239,433,35,1561,1364,254,483,3074,434,1699,3144,637,988,737,1515,3001,225,1024,2861,248,553,464,384,1813,1755,36,101,2427,116,3075,416,683,2429,3129,921,107,653,3286,154,1152,334,3335,840,955,1662,879,528,1565,780,1897,2389,486,3342,2202,74,155,279 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| 3,406 |
Nuclear outer membrane endoplasmic reticulum membrane network | 74 | 333 | 4.480512 | 0.000007 | Q6NUQ4,Q9H0U3,Q92575,Q07065,Q9P2W9,Q9H6H4,Q9BVC6,Q8N4V1,Q6UX53,O00400,O43852,Q9H0U4,Q86UL3,Q9BUN8,Q969M3,Q92604,Q96HY6,Q9Y3A6,Q96PC5,Q12981,Q96G23,P57088,O75845,O95470,Q13445,Q15041,P51572,P20340,P35610,Q07812,Q6RW13,P48449,P62854,P46977,P67812,P24390,Q5BJF2,P51648,Q9UBU6,Q14165,O00767,Q9UHQ4,Q9Y320,Q96N66,Q9NQC3,Q86UE4,O95197,Q15392,O60725,O95772,O75396,Q06136,Q6NTF9,O95864,A1L0T0,Q96AG4,Q9UKR5,P61106,P50402,Q15629,O95070,Q9UHQ9,Q96AA3,Q16850,O75844,P51809,Q16799,Q969X5,Q9UM00,Q6Y1H2,O14735,O15260,Q8NBI6,P55061 | Localization | GO Cellular component | msigdb_gocc | 129,130,261,133,6,134,141,9,140,13,135,274,144,17,153,152,25,289,157,160,166,164,168,169,42,43,172,177,179,180,181,55,188,309,189,60,61,187,323,320,67,72,334,75,76,208,328,207,81,83,337,217,87,338,336,91,92,350,349,98,226,237,105,106,231,361,111,112,113,246,238,118,252,126 | 2163,336,529,2390,2647,13,1332,530,2948,67,2466,3278,238,1614,578,1246,1371,620,118,1821,743,1030,2864,3396,135,1823,956,1208,81,1950,1121,2435,337,1523,1033,231,168,2579,2362,600,3004,2470,2580,2742,226,328,1375,169,559,687,2436,358,83,338,1162,889,2649,689,2437,2294,1377,810,2249,1252,2794,892,3354,1525,2686,2924,1294,2654,2173,177,1216,1955,60,1381,2908,3007,2824,1432,2296,2747,2925,855,1874,2770,179,2593,1079,1255,1301,815,816,3258,309,2130,55,1038,1387,3034,1166,2547,817,2175,349,2513,172,187,361,2514,1630,1168,1219,126,1914,164,537,661,1130,758,3022,2598,2217,350,511,2550,585,1392,1393,1915,188,789,3379,760,2047,189,2220,1346,2479,1964,3272,217,133,180,1003,1262,822,1004,1005,160,726,1836,42,2803,1224,3361,320,728,764,628,1777,3248,43,1444,2413,3188,207,2629,1920,98,513,1779,2805,111,106,1842,1011,61,2183,2142,1448,672,1589,1012,87,1132,1923,129,2727,3211,1098,181,140,246,3280,518,3093,208,144,866,1738,1847,1739,3212,479,1403,9,1972,1352,459,2966,1790,2189,252,1017,1690,546,460,2854,1454,977,1182,1455,1976,1643,2490,2191,1353,547,2563,261,152,1741,704,153,2059,3249,112,1053,105,91,2015,166,1141,2423,25,1187,1143,75,157,1552,679,796,650,1235,2670,2459,3362,411,706,3277,1802,2530,2639,2640,2199,3265,17,141,1747,482,1651,709,774,130,274,1286,1984,502,3153,1191,134,1604,3029,873,2569,1239,1657,987,76,2535,1288,637,3250,1024,1754,2707,2734,2354,711,576,1114,6,3031,2427,3146,323,2944,3213,1609,72,237,92,3129,2862,113,779,3204,334,1611,289,3243,2576,2500,781,2946,1819,1329,2433,803,804 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| 3,406 |
Mitochondria | 150 | 413 | 3.732637 | 0.000189 | P48735,Q9Y3D6,O43772,P12235,P30405,Q9HCL2,O43819,Q96C36,Q9NUJ1,Q9UIJ7,Q9NSE4,Q9NZ45,O43674,P21912,Q9H4I3,Q9NPL8,Q9HC21,P28070,Q16836,P82663,Q9H3K2,P24539,Q8IWA4,Q9Y6V7,P45954,O95202,Q4G176,O75127,Q92667,O95139,P82675,Q9NWS8,P17152,Q7KZN9,Q8TB36,Q07820,Q9BSH4,Q9NQ29,P05165,P51649,P62072,Q9Y277,Q9NUQ2,Q9BYD2,Q9UBX3,Q16795,Q5HYK3,Q5VT66,P22570,O15121,Q9Y2Q9,Q96TA2,P82912,Q9BYT8,Q8NAN2,Q7L2E3,P49406,P42126,Q6P1L8,Q8IXI1,Q9Y6C9,Q9UJS0,Q5HYI7,P23786,O75648,O14734,Q9Y606,P82914,Q92552,Q9BT17,Q96IX5,P08574,O75306,Q96NB2,Q8N983,P31040,Q02218,Q14318,Q9NP81,O00483,Q9NVH1,P10606,O43615,O75431,O75616,Q96AB3,Q6PI48,Q8NCM8,Q9UHQ9,Q9NX40,Q15386,Q6DKI1,Q9NYK5,Q969Y2,Q6KCM7,Q9Y4W6,P82930,Q9NQG6,Q5T9A4,O14874,P31930,O75439,O95831,Q9Y6M9,P51398,P08559,Q15070,Q9BW91,P57105,Q6UXV4,Q9BZE1,Q7Z2W9,Q9NXF1,O00411,P21359,Q5JRX3,Q96RQ3,Q96EY8,Q96HS1,P11310,O75964,Q9Y2Z4,Q9H2D1,P40939,Q9P015,O95140,P11498,Q9H936,Q96AY3,Q9GZY8,O95182,O95168,Q96EY1,Q8NBN7,Q96SY0,P00367,Q9Y3E5,Q9H2U1,Q96DV4,Q14197,P05141,Q9NQZ5,Q9NVV4,Q9Y5J7,Q8N2F6,Q66PJ3,O75390,P12236,Q9HD33,Q3SXM5 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 2,528,7,507,509,12,505,550,22,24,552,553,26,535,34,35,39,536,41,539,45,46,573,577,561,558,63,557,591,78,586,90,85,612,94,96,97,616,602,606,104,107,637,634,116,114,122,123,622,620,653,651,131,132,647,645,642,641,674,675,155,683,161,159,659,657,175,173,703,707,182,690,184,201,200,693,695,728,735,205,737,716,714,715,222,229,765,766,237,236,233,244,248,247,245,780,762,254,251,742,249,746,259,279,755,750,271,798,268,286,298,295,315,303,307,331,333,332,343,339,346,371,370,360,384,373,387,414,410,412,403,402,428,425,446,438,466,462,461,455,452,483,485,486,479,477,467,470,503,498 | 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| 3,406 |
Organelle subcompartment | 87 | 413 | 3.442503 | 0.000576 | Q9HC07,Q9P2W9,Q8N4V1,O00400,Q9BUN8,Q8TBA6,Q96HY6,Q96A57,Q13445,Q15041,P48449,P24390,Q5BJF2,O00767,Q9UHQ4,Q96N66,Q9NQC3,O60725,O95772,Q9H4A6,Q6NTF9,Q96AG4,Q9UKR5,Q15629,Q96AA3,Q16850,Q16799,Q969X5,Q9UM00,O15127,O15260,P55061,Q6NUQ4,Q9H0U3,Q07065,Q9H6H4,Q9BVC6,Q6UX53,O43852,Q86UL3,Q969M3,Q92604,Q96PC5,Q12981,Q96G23,Q9H4A5,P57088,O75845,O95470,P51572,P20340,P35610,Q07812,Q6RW13,P62854,P67812,P51648,Q86UE4,Q96ED9,Q15392,Q06136,O43752,O95070,Q9UHQ9,O75844,Q6Y1H2,O14735,P61966,Q8NBI6,Q92575,P53365,Q9H0U4,Q9Y3A6,P83436,P46977,Q9UBU6,Q14165,Q9Y320,O00443,O95197,O75396,O95864,A1L0T0,P61106,P50402,P51809,O95674 | Localization | GO Cellular component | msigdb_gocc | 5,6,9,13,17,18,25,29,42,43,55,60,61,67,72,75,76,81,83,89,87,91,92,98,105,106,111,112,113,117,118,126,129,130,133,134,141,140,135,144,153,152,157,160,166,167,164,168,169,172,177,179,180,181,188,189,187,208,210,207,217,221,226,237,231,246,238,240,252,261,260,274,289,282,309,323,320,334,326,328,337,338,336,350,349,361,358 | 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