term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5 values | subtype stringclasses 24 values | subtype_key stringclasses 24 values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingolipid metabolic process | 17 | 33 | 3.592807 | 0.000327 | P07602,P50897,Q96G23,P04062,P17900,Q16880,P06865,Q13510,Q9NZJ7,Q16739,O95470,Q06136,P16278,Q9NRA0,Q53H12,Q6Y1H2,P06280 | Processes and pathways | GO Biological process | msigdb_gobp | 32,1,66,195,134,104,422,75,335,146,187,210,376,475,443,444,383 | 3364,510,1602,187,195,383,422,32,2184,376,134,2057,1993,855,1383,1,210,828,937,75,146,104,443,444,679,66,668,475,1376,837,335,2691,1224 | -1.7278133504168929,0.8362984856412491,-0.09593126943002946,1.7820457887243357,1.72307457356377,1.0760741454068623,1.010349571326269,3.202436833742072,-0.3842701148909007,1.0891399743619552,2.1140159037622634,-0.3190719005092798,-0.2867183612159623,0.38691633847751733,0.028199720326965952,4.079438950901208,1.651602135580465,0.415932129064235,0.3138038545974289,2.546060857024669,2.0466941864597326,2.333576542930749,0.9705945223247175,0.9705945223247175,0.5873548038204078,2.711259409326985,0.6014378848555904,0.9172078124078225,0.043549855895539176,0.415932129064235,1.2183796925819346,-0.617805031632897,0.1348936174475735 | 3,417 |
Mitochondrial respiratory chain complex assembly | 19 | 38 | 3.534601 | 0.000408 | Q9BSK2,Q9Y6M9,Q9Y2R0,Q6DKK2,Q96CU9,O43819,O95831,Q69YU5,Q9H061,O43676,Q9P0J0,O95299,O95168,O75880,P03886,O95139,Q15070,O43674,Q8N8Q8 | Processes and pathways | GO Biological process | msigdb_gobp | 3,524,5,136,395,515,149,21,23,25,419,420,561,59,72,207,100,229,108 | 3295,229,25,515,1812,1858,839,1335,59,207,561,420,149,889,72,3280,577,1934,100,2759,1369,1006,21,136,1074,108,395,1302,3,2246,23,2314,1514,419,1549,5,695,524 | -1.3360226676213207,1.5914407759518774,3.2777569763908665,0.8227153339568873,-0.2065373586035809,-0.22249405275792178,0.4014404547791768,0.05886364960372865,2.7620488324659895,1.651602135580465,0.7680975338781076,1.010349571326269,2.012773197487723,0.35777018045817044,2.598130352078956,-1.2981337870876661,0.7406157866680001,-0.25452629436448265,2.3658887117772305,-0.668970176567426,0.043549855895539176,0.2695373236736853,3.41672208839756,2.1028433404883855,0.22496634533860416,2.2684732013809596,1.0498637286274306,0.08938291553650131,4.079438950901208,-0.4006732349357356,3.3707223205539893,-0.43360527729208703,-0.033567813428752,1.0235475745145948,-0.049102349624348285,4.079438950901208,0.5732411343760665,0.8227153339568873 | 3,417 |
Monovalent inorganic cation homeostasis | 14 | 31 | 3.435785 | 0.000591 | Q05086,P50897,Q96PU5,Q93050,P05023,P06576,Q9Y5X3,Q9Y487,Q15904,O75787,Q92544,O75503,Q8N511,Q9HC07 | Processes and pathways | GO Biological process | msigdb_gobp | 192,1,67,135,511,421,397,274,634,211,379,315,95,31 | 315,211,1555,900,511,2224,421,824,1465,1178,1,1067,779,1469,1432,1644,192,634,95,379,135,2009,67,1373,31,1015,1457,274,397,3141,646 | 1.2693678996019138,1.6396139556611513,-0.06467431361864844,0.3431478364322099,0.8362984856412491,-0.4006732349357356,1.010349571326269,0.415932129064235,-0.018070520659702844,0.14999301851452415,4.079438950901208,0.22496634533860416,0.45921398013028775,-0.018070520659702844,-0.0026102883160087067,-0.11161663697128474,1.7349112933227129,0.6574670293566639,2.3980433462775825,1.0891399743619552,2.1140159037622634,-0.2867183612159623,2.7010545612582533,0.043549855895539176,3.2118986899262745,0.2695373236736853,-0.0026102883160087067,1.4323854934737215,1.0498637286274306,-0.9848254487759778,0.6435049519950851 | 3,417 |
Endoplasmic reticulum golgi intermediate compartment membrane | 19 | 31 | 3.39493 | 0.000686 | Q9Y3B3,Q96RQ1,P53634,P51572,P61019,P24390,Q15363,P49755,Q08379,Q969X5,Q9Y3A6,Q9Y282,O95070,Q8N511,Q9BVK6,O14653,Q15904,Q10472,Q9H0U4 | Localization | GO Cellular component | msigdb_gocc | 537,276,527,402,541,44,46,440,578,193,327,83,216,95,352,358,634,377,253 | 358,2667,758,1041,216,44,3178,650,440,402,527,541,2036,578,377,829,1295,1474,46,1100,634,2206,95,193,799,276,352,253,83,327,537 | 1.1281812332227774,-0.617805031632897,0.47357736156305924,0.23985743121252281,1.6276038128114534,3.000556997593149,-1.075394715606791,0.6295128244024532,0.9705945223247175,1.0367189234918222,0.8091037855865696,0.7954637182819312,-0.3028748428550267,0.7406157866680001,1.0891399743619552,0.415932129064235,0.08938291553650131,-0.018070520659702844,2.9810060001650047,0.2100409512222278,0.6574670293566639,-0.3842701148909007,2.3980433462775825,1.7349112933227129,0.44481874473177313,1.4199889089821724,1.1669903758343456,1.4940186536364441,2.504107696101658,1.2439235324069875,0.8091037855865696 | 3,417 |
Protein insertion into membrane | 16 | 34 | 3.394325 | 0.000688 | P46379,Q9P0J0,Q9Y5J7,Q15070,Q15629,Q8N8Q8,Q8N4V1,Q9Y5J9,Q9NS69,O60220,P62072,Q9NPA0,Q53H12,Q96A33,Q9Y584,O14737 | Processes and pathways | GO Biological process | msigdb_gobp | 226,419,164,100,42,108,14,347,19,460,56,220,443,284,30,255 | 255,1040,549,1551,460,2600,1690,1692,3086,226,618,1259,56,828,816,100,42,443,659,14,2376,108,1300,284,220,19,3386,419,1549,695,30,164,347,477 | 1.481738356319479,0.23985743121252281,0.7817950089963721,-0.06467431361864844,0.9305955446314544,-0.583919668151991,-0.14310210131811343,-0.14310210131811343,-0.9310917159637686,1.6035173065048012,0.6713991887930522,0.1045887365929969,2.7923363998378443,0.415932129064235,0.43039150987620567,2.3658887117772305,3.1070691737442258,0.9705945223247175,0.6154905133855352,3.5707848317991115,-0.46670653209308793,2.2684732013809596,0.08938291553650131,1.382657610013963,1.6276038128114534,3.5258411651536656,-2.2103407897809766,1.0235475745145948,-0.049102349624348285,0.5732411343760665,3.221347085581454,1.9214522256714823,1.1798756638524783,0.9172078124078225 | 3,417 |
Mitochondrial protein import | 17 | 36 | 3.296522 | 0.000979 | Q9Y5J7,P21796,Q9Y5L4,O14925,Q13505,Q10713,P06576,P12235,O43615,Q9NS69,Q99595,O60220,O60830,P62072,Q9Y5J9,P12236,Q9Y584 | Processes and pathways | Reactome Pathways | msigdb_reactome | 164,69,477,201,105,107,421,365,496,19,52,460,22,56,347,470,30 | 201,496,460,22,3174,1063,2327,1429,2600,1177,421,1312,3225,365,470,69,759,3212,56,107,105,633,1101,1479,52,3136,1660,19,546,1226,1549,695,30,164,347,477 | 1.6993368662863828,0.8633800839961283,0.9305955446314544,3.389160419925041,-1.075394715606791,0.22496634533860416,-0.4501346415467144,-0.0026102883160087067,-0.583919668151991,0.14999301851452415,1.010349571326269,0.07414127779889645,-1.1487833229977529,1.1151934116250275,0.9172078124078225,2.63949253044833,0.47357736156305924,-1.1303571839723463,2.7923363998378443,2.2902458390004905,2.301105245667895,0.6574670293566639,0.2100409512222278,-0.018070520659702844,2.8923057086966835,-0.9848254487759778,-0.11161663697128474,3.5258411651536656,0.7954637182819312,0.1348936174475735,-0.049102349624348285,0.5732411343760665,3.221347085581454,1.9214522256714823,1.1798756638524783,0.9172078124078225 | 3,417 |
Sphingolipid metabolism | 17 | 29 | 3.286161 | 0.001016 | P07602,Q96G23,P04062,P17900,P10619,Q16880,P06865,Q13510,Q9NZJ7,Q16739,Q06136,P16278,P51648,Q9NRA0,O95470,O15269,P06280 | Processes and pathways | Reactome Pathways | msigdb_reactome | 32,66,195,134,388,104,422,75,335,146,210,376,24,475,187,510,383 | 1666,3364,510,1602,549,2809,187,195,383,422,32,2184,388,376,134,1993,855,24,210,75,146,104,2069,66,2713,475,1376,335,1224 | -0.1273401837881595,-1.7278133504168929,0.8362984856412491,-0.09593126943002946,0.7817950089963721,-0.7033078821496582,1.7820457887243357,1.72307457356377,1.0760741454068623,1.010349571326269,3.202436833742072,-0.3842701148909007,1.0629820996007722,1.0891399743619552,2.1140159037622634,-0.2867183612159623,0.38691633847751733,3.3614840657953646,1.651602135580465,2.546060857024669,2.0466941864597326,2.333576542930749,-0.3190719005092798,2.711259409326985,-0.6348148888478948,0.9172078124078225,0.043549855895539176,1.2183796925819346,0.1348936174475735 | 3,417 |
Membrane lipid metabolic process | 18 | 40 | 3.251537 | 0.001148 | P07602,P50897,Q96G23,P04062,Q99735,P17900,Q16880,P06865,Q13510,Q9NZJ7,Q16739,O95470,Q06136,P16278,Q9NRA0,Q53H12,Q6Y1H2,P06280 | Processes and pathways | GO Biological process | msigdb_gobp | 32,1,66,195,482,134,104,422,75,335,146,187,210,376,475,443,444,383 | 3364,510,1602,2023,187,195,1310,383,422,32,2184,376,134,2057,1993,855,1383,1,210,828,937,75,146,104,443,444,2616,679,1263,2169,66,2104,482,668,475,1376,837,335,2691,1224 | -1.7278133504168929,0.8362984856412491,-0.09593126943002946,-0.3028748428550267,1.7820457887243357,1.72307457356377,0.07414127779889645,1.0760741454068623,1.010349571326269,3.202436833742072,-0.3842701148909007,1.0891399743619552,2.1140159037622634,-0.3190719005092798,-0.2867183612159623,0.38691633847751733,0.028199720326965952,4.079438950901208,1.651602135580465,0.415932129064235,0.3138038545974289,2.546060857024669,2.0466941864597326,2.333576542930749,0.9705945223247175,0.9705945223247175,-0.583919668151991,0.5873548038204078,0.1045887365929969,-0.36790863721425243,2.711259409326985,-0.33530974411801295,0.9037925174593933,0.6014378848555904,0.9172078124078225,0.043549855895539176,0.415932129064235,1.2183796925819346,-0.617805031632897,0.1348936174475735 | 3,417 |
Intrinsic component of mitochondrial membrane | 28 | 53 | 3.195935 | 0.001394 | Q9Y2R0,O43819,Q16891,O60830,O95563,Q9NX63,Q9H3K2,Q8IWA4,Q6P4A7,P57105,Q9Y3D6,Q99595,P17152,O75880,Q53H12,Q6UXV4,Q5XKP0,Q16134,O14925,Q8TB36,Q9HC21,Q15070,Q9UG56,Q13505,Q8N8Q8,P12235,Q9BWH2,Q15388 | Localization | GO Cellular component | msigdb_gocc | 5,515,529,22,656,546,33,678,171,173,694,52,434,59,443,449,198,584,201,480,228,100,622,105,108,365,112,633 | 201,515,22,1063,59,2600,1492,656,1177,365,434,3212,1641,1431,173,904,105,100,633,584,529,443,1005,198,171,449,678,2403,1835,108,1877,480,1054,769,52,835,785,112,1079,33,1572,1170,228,1425,2658,1154,546,622,1546,5,694,1273,695 | 1.6993368662863828,0.8227153339568873,3.389160419925041,0.22496634533860416,2.7620488324659895,-0.583919668151991,-0.033567813428752,0.6154905133855352,0.14999301851452415,1.1151934116250275,0.9838731573525725,-1.1303571839723463,-0.11161663697128474,-0.0026102883160087067,1.8637254027658279,0.3431478364322099,2.301105245667895,2.3658887117772305,0.6574670293566639,0.7268312627826058,0.8091037855865696,0.9705945223247175,0.2695373236736853,1.711216457757838,1.8753114211973756,0.9572887845888515,0.5873548038204078,-0.4833211743492699,-0.2065373586035809,2.2684732013809596,-0.22249405275792178,0.9037925174593933,0.23985743121252281,0.47357736156305924,2.8923057086966835,0.415932129064235,0.45921398013028775,2.2575598483675283,0.22496634533860416,3.202436833742072,-0.06467431361864844,0.165057285462392,1.6035173065048012,0.012813065246235574,-0.6008400388890252,0.180086585856304,0.7954637182819312,0.6713991887930522,-0.049102349624348285,4.079438950901208,0.5732411343760665,0.1045887365929969,0.5732411343760665 | 3,417 |
Anion transmembrane transport | 18 | 44 | 3.157895 | 0.001589 | Q15041,Q9HC21,P08183,Q9Y619,P21796,P30825,Q02978,O60831,Q9Y277,Q9UHG3,P12235,Q9UBX3,Q9H2D1,O43808,Q8TB61,P51798,P45880,P12236 | Processes and pathways | GO Biological process | msigdb_gobp | 160,228,323,36,69,40,456,232,76,205,365,109,176,236,86,403,60,470 | 2882,236,232,1429,2722,656,900,775,952,323,1231,365,470,69,40,3072,60,779,639,403,879,827,1432,904,456,160,2005,1164,86,846,769,1373,176,506,1572,228,1884,109,205,1226,76,1807,36,646 | -0.7551608870541102,1.567220738704834,1.5793419482693727,-0.0026102883160087067,-0.651869854997686,0.6154905133855352,0.3431478364322099,0.45921398013028775,0.2990819080544139,1.2439235324069875,0.1197589134781991,1.1151934116250275,0.9172078124078225,2.63949253044833,3.1070691737442258,-0.9132800387870509,2.751922092384719,0.45921398013028775,0.6435049519950851,1.0367189234918222,0.37235963057923405,0.415932129064235,-0.0026102883160087067,0.3431478364322099,0.9439558302360769,1.944401687938058,-0.2867183612159623,0.165057285462392,2.4830307358799764,0.4014404547791768,0.47357736156305924,0.043549855895539176,1.8521189098662278,0.8498533620967631,-0.06467431361864844,1.6035173065048012,-0.22249405275792178,2.2684732013809596,1.6755129356232892,0.1348936174475735,2.546060857024669,-0.19062001449545884,3.1453808033753354,0.6435049519950851 | 3,417 |
Retrograde vesicle mediated transport golgi to endoplasmic reticulum | 18 | 33 | 3.112696 | 0.001854 | P20340,P18085,Q969X5,Q9H4A6,Q9P2W9,Q12907,O15258,Q12981,Q6NUQ1,P24390,O43731,Q9Y282,Q96RQ1,Q8TD16,P48444,P49755,P84085,Q96JB2 | Processes and pathways | GO Biological process | msigdb_gobp | 699,698,193,131,4,829,483,249,586,44,110,83,276,499,777,440,780,445 | 993,994,483,110,1041,698,699,44,1781,2230,777,2117,440,2088,1095,861,780,1824,829,249,586,499,1974,1741,193,445,276,2138,131,1745,4,2020,83 | 0.2695373236736853,0.2695373236736853,0.8903495429355509,2.2575598483675283,0.23985743121252281,0.5590967396986621,0.5590967396986621,3.000556997593149,-0.19062001449545884,-0.4006732349357356,0.45921398013028775,-0.3515885852686711,0.9705945223247175,-0.33530974411801295,0.2100409512222278,0.38691633847751733,0.45921398013028775,-0.2065373586035809,0.415932129064235,1.5185103694031445,0.7268312627826058,0.8633800839961283,-0.27060224728382676,-0.15890258245488978,1.7349112933227129,0.9705945223247175,1.4199889089821724,-0.3515885852686711,2.13630429417419,-0.15890258245488978,4.079438950901208,-0.2867183612159623,2.504107696101658 | 3,417 |
Organic anion transport | 19 | 48 | 3.100079 | 0.001935 | O00400,P14174,P07602,Q15041,Q9Y619,P30825,Q9H2D1,Q02978,Q9NZJ7,Q08722,Q8TB61,Q6NUK1,P12236,Q6KCM7,Q9HC21,O60831,P12235,Q9UBX3,O43808 | Processes and pathways | GO Biological process | msigdb_gobp | 16,28,32,160,36,40,176,456,335,84,86,474,470,222,228,232,365,109,236 | 16,2353,2882,236,232,1429,2722,656,1409,900,775,952,32,1231,365,470,28,891,570,40,3072,879,827,1432,456,84,937,160,2237,2005,222,474,1970,86,846,769,770,176,1303,506,1572,228,335,109,1401,1226,36,646 | 3.5618203282976997,-0.46670653209308793,-0.7551608870541102,1.567220738704834,1.5793419482693727,-0.0026102883160087067,-0.651869854997686,0.6154905133855352,0.012813065246235574,0.3431478364322099,0.45921398013028775,0.2990819080544139,3.202436833742072,0.1197589134781991,1.1151934116250275,0.9172078124078225,3.221347085581454,0.35777018045817044,0.7543711682631408,3.1070691737442258,-0.9132800387870509,0.37235963057923405,0.415932129064235,-0.0026102883160087067,0.9439558302360769,2.493577626661402,0.3138038545974289,1.944401687938058,-0.4006732349357356,-0.2867183612159623,1.6155716241957836,0.9172078124078225,-0.27060224728382676,2.4830307358799764,0.4014404547791768,0.47357736156305924,0.47357736156305924,1.8521189098662278,0.08938291553650131,0.8498533620967631,-0.06467431361864844,1.6035173065048012,1.2183796925819346,2.2684732013809596,0.028199720326965952,0.1348936174475735,3.1453808033753354,0.6435049519950851 | 3,417 |
Biliary tract abnormality | 11 | 26 | 3.089594 | 0.002004 | P07602,O96028,Q14108,P04062,Q5XKP0,Q10713,P09601,Q9NSD9,Q14739,P14174,O95202 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,318,98,195,198,107,11,20,212,28,127 | 549,127,318,502,195,32,11,28,2972,1994,1782,917,2118,107,1141,2645,98,212,198,1396,847,20,335,850,1549,793 | 0.7817950089963721,2.1474202525907056,1.256658100316569,0.8498533620967631,1.72307457356377,3.202436833742072,3.6154272920019888,3.221347085581454,-0.8249557647149923,-0.2867183612159623,-0.19062001449545884,0.32849244575329073,-0.3515885852686711,2.2902458390004905,0.180086585856304,-0.6008400388890252,2.387342541189054,1.6396139556611513,1.711216457757838,0.028199720326965952,0.4014404547791768,3.5168159185133003,1.2183796925819346,0.4014404547791768,-0.049102349624348285,0.45921398013028775 | 3,417 |
Lysosome | 24 | 58 | 3.08294 | 0.00205 | P50897,Q15012,P10619,P17900,Q93050,Q9Y487,O15118,P20645,P07602,P08236,P10253,P07858,O75503,P11117,P04062,Q13510,Q9NZJ7,O14773,Q9UMR5,Q14108,P54802,P16278,P07711,P06280 | Processes and pathways | KEGG Pathways | msigdb_kegg | 1,6,388,134,135,274,148,277,32,289,170,184,315,189,195,75,335,206,82,98,103,376,119,383 | 2985,1575,1404,206,148,549,2147,315,195,1310,383,422,32,2184,119,184,289,2504,1606,2258,170,388,189,751,1956,876,915,376,134,277,1093,3344,1,2364,527,103,1183,1644,1344,982,2644,2514,75,98,6,634,679,1682,135,925,722,1033,335,1457,2663,82,1108,274 | -0.8425236583575074,-0.080283891168658,0.012813065246235574,1.651602135580465,2.012773197487723,0.7817950089963721,-0.36790863721425243,1.2693678996019138,1.72307457356377,0.07414127779889645,1.0760741454068623,1.010349571326269,3.202436833742072,-0.3842701148909007,2.191697356585309,1.8054866977683843,1.345112044634575,-0.5334238928726274,-0.09593126943002946,-0.41711821570494334,1.8753114211973756,1.0629820996007722,1.7702938658351084,0.48790903352268455,-0.27060224728382676,0.37235963057923405,0.32849244575329073,1.0891399743619552,2.1140159037622634,1.4075687949647808,0.2100409512222278,-1.5289120558488012,4.079438950901208,-0.46670653209308793,0.8091037855865696,2.333576542930749,0.14999301851452415,-0.11161663697128474,0.05886364960372865,0.2843264501176428,-0.6008400388890252,-0.5334238928726274,2.546060857024669,2.387342541189054,4.0711326084955255,0.6574670293566639,0.5873548038204078,-0.1273401837881595,2.1140159037622634,0.32849244575329073,0.5307152226992892,0.25471437049160844,1.2183796925819346,-0.0026102883160087067,-0.6008400388890252,2.504107696101658,0.2100409512222278,1.4323854934737215 | 3,417 |
Organic anion transmembrane transporter activity | 13 | 30 | 3.06934 | 0.002145 | Q9HC21,Q9Y619,P30825,Q02978,P12235,Q9UBX3,O43808,O00400,Q9H2D1,Q8TB61,Q6NUK1,P12236,Q6KCM7 | Functions | GO Molecular function | msigdb_gomf | 228,36,40,456,365,109,236,16,176,86,474,470,222 | 16,2353,2882,236,1429,656,775,1231,365,470,40,3072,879,827,456,2005,222,474,1970,86,769,770,176,506,1572,228,109,1226,36,646 | 3.5618203282976997,-0.46670653209308793,-0.7551608870541102,1.567220738704834,-0.0026102883160087067,0.6154905133855352,0.45921398013028775,0.1197589134781991,1.1151934116250275,0.9172078124078225,3.1070691737442258,-0.9132800387870509,0.37235963057923405,0.415932129064235,0.9439558302360769,-0.2867183612159623,1.6155716241957836,0.9172078124078225,-0.27060224728382676,2.4830307358799764,0.47357736156305924,0.47357736156305924,1.8521189098662278,0.8498533620967631,-0.06467431361864844,1.6035173065048012,2.2684732013809596,0.1348936174475735,3.1453808033753354,0.6435049519950851 | 3,417 |
Anion transmembrane transporter activity | 31 | 49 | 3.042251 | 0.002348 | P51797,O00400,P05141,O95563,P51798,P51790,Q9Y619,P30825,O43681,Q9H2D1,P45880,P53985,P21796,Q15043,P0CG08,Q02978,Q9C0H2,Q9Y277,Q8TB61,Q6NUK1,Q96S66,P12236,Q6KCM7,Q9HC21,P12235,Q9UBX3,O43808,Q9H936,Q99808,Q96NB2,Q9Y6M7 | Functions | GO Molecular function | msigdb_gomf | 639,16,775,656,403,779,36,40,549,176,60,827,69,326,824,456,202,76,86,474,346,470,222,228,365,109,236,506,770,769,646 | 2866,16,2353,2882,549,236,1429,656,900,775,1231,824,365,470,69,40,3072,60,779,639,403,879,827,1432,456,326,2005,1164,222,474,1970,86,846,769,346,770,1373,202,176,506,1572,228,1488,109,1226,76,36,3141,646 | -0.7378300187664318,3.5618203282976997,-0.46670653209308793,-0.7551608870541102,0.7817950089963721,1.567220738704834,-0.0026102883160087067,0.6154905133855352,0.3431478364322099,0.45921398013028775,0.1197589134781991,0.415932129064235,1.1151934116250275,0.9172078124078225,2.63949253044833,3.1070691737442258,-0.9132800387870509,2.751922092384719,0.45921398013028775,0.6435049519950851,1.0367189234918222,0.37235963057923405,0.415932129064235,-0.0026102883160087067,0.9439558302360769,1.2439235324069875,-0.2867183612159623,0.165057285462392,1.6155716241957836,0.9172078124078225,-0.27060224728382676,2.4830307358799764,0.4014404547791768,0.47357736156305924,1.1927355777835806,0.47357736156305924,0.043549855895539176,1.6993368662863828,1.8521189098662278,0.8498533620967631,-0.06467431361864844,1.6035173065048012,-0.018070520659702844,2.2684732013809596,0.1348936174475735,2.546060857024669,3.1453808033753354,-0.9848254487759778,0.6435049519950851 | 3,417 |
Lytic vacuole organization | 11 | 26 | 3.027668 | 0.002464 | P50897,Q14108,P04062,P54802,P10253,O14773,Q96ED9,O75787,P11117,Q8N511,Q9HC07 | Processes and pathways | GO Biological process | msigdb_gobp | 1,98,195,103,170,206,182,211,189,95,31 | 2985,206,315,211,195,2184,170,189,562,1,1067,103,1184,619,98,660,988,95,2009,182,1450,31,3342,1377,1687,1550 | -0.8425236583575074,1.651602135580465,1.2693678996019138,1.6396139556611513,1.72307457356377,-0.3842701148909007,1.8753114211973756,1.7702938658351084,0.7680975338781076,4.079438950901208,0.22496634533860416,2.333576542930749,0.14999301851452415,0.6713991887930522,2.387342541189054,0.6154905133855352,0.2843264501176428,2.3980433462775825,-0.2867183612159623,1.8171758374827531,-0.0026102883160087067,3.2118986899262745,-1.5093588210105136,0.043549855895539176,-0.1273401837881595,-0.049102349624348285 | 3,417 |
Inner mitochondrial membrane organization | 16 | 25 | 3.020202 | 0.002526 | Q9H3K2,Q9P0J0,Q9Y5J7,Q6UXV4,Q5XKP0,Q9Y5L4,O60313,Q13505,Q9Y5J9,O60220,Q16891,P17152,P62072,Q53H12,Q9Y584,O95202 | Processes and pathways | GO Biological process | msigdb_gobp | 33,419,164,449,198,477,294,105,347,460,529,434,56,443,30,127 | 460,294,1063,2600,127,434,3212,56,105,529,443,1005,198,449,1300,33,1154,546,419,1273,695,30,164,347,477 | 0.9305955446314544,1.3199613772518044,0.22496634533860416,-0.583919668151991,2.1474202525907056,0.9838731573525725,-1.1303571839723463,2.7923363998378443,2.301105245667895,0.8091037855865696,0.9705945223247175,0.2695373236736853,1.711216457757838,0.9572887845888515,0.08938291553650131,3.202436833742072,0.180086585856304,0.7954637182819312,1.0235475745145948,0.1045887365929969,0.5732411343760665,3.221347085581454,1.9214522256714823,1.1798756638524783,0.9172078124078225 | 3,417 |
Cellular monovalent inorganic cation homeostasis | 13 | 28 | 3.013113 | 0.002586 | Q05086,P50897,Q96PU5,Q93050,P05023,P06576,Q9Y487,Q15904,O75787,Q92544,O75503,Q8N511,Q9HC07 | Processes and pathways | GO Biological process | msigdb_gobp | 192,1,67,135,511,421,274,634,211,379,315,95,31 | 315,211,900,511,2224,421,824,1465,1178,1,1067,779,1469,1432,1644,192,634,95,379,135,2009,67,31,1015,1457,274,3141,646 | 1.2693678996019138,1.6396139556611513,0.3431478364322099,0.8362984856412491,-0.4006732349357356,1.010349571326269,0.415932129064235,-0.018070520659702844,0.14999301851452415,4.079438950901208,0.22496634533860416,0.45921398013028775,-0.018070520659702844,-0.0026102883160087067,-0.11161663697128474,1.7349112933227129,0.6574670293566639,2.3980433462775825,1.0891399743619552,2.1140159037622634,-0.2867183612159623,2.7010545612582533,3.2118986899262745,0.2695373236736853,-0.0026102883160087067,1.4323854934737215,-0.9848254487759778,0.6435049519950851 | 3,417 |
SLC25 family of mitochondrial transporters | 14 | 21 | 2.987582 | 0.002812 | Q9HC21,Q9BSK2,Q9Y619,Q02978,Q9NZJ7,Q70HW3,Q9Y6C9,Q9H2D1,P12235,Q9UBX3,O43808,Q6NUK1,P12236,Q6KCM7 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 228,3,36,456,335,142,305,176,365,109,236,474,470,222 | 1723,236,1429,775,365,470,879,904,456,222,474,142,3,176,506,228,335,109,1226,36,305 | -0.15890258245488978,1.567220738704834,-0.0026102883160087067,0.45921398013028775,1.1151934116250275,0.9172078124078225,0.37235963057923405,0.3431478364322099,0.9439558302360769,1.6155716241957836,0.9172078124078225,2.0804411470022126,4.079438950901208,1.8521189098662278,0.8498533620967631,1.6035173065048012,1.2183796925819346,2.2684732013809596,0.1348936174475735,3.1453808033753354,1.2947135868342938 | 3,417 |
Mitochondrial substrate/solute carrier [IPR018108] | 14 | 21 | 2.987582 | 0.002812 | Q9HC21,Q9BSK2,Q9Y619,Q02978,Q9NZJ7,Q70HW3,Q9Y6C9,Q9H2D1,P12235,Q9UBX3,O43808,Q6NUK1,P12236,Q6KCM7 | Sequence | InterPro Repeat | interpro_repeat | 228,3,36,456,335,142,305,176,365,109,236,474,470,222 | 1723,236,1429,775,365,470,879,904,456,222,474,142,3,176,506,228,335,109,1226,36,305 | -0.15890258245488978,1.567220738704834,-0.0026102883160087067,0.45921398013028775,1.1151934116250275,0.9172078124078225,0.37235963057923405,0.3431478364322099,0.9439558302360769,1.6155716241957836,0.9172078124078225,2.0804411470022126,4.079438950901208,1.8521189098662278,0.8498533620967631,1.6035173065048012,1.2183796925819346,2.2684732013809596,0.1348936174475735,3.1453808033753354,1.2947135868342938 | 3,417 |
Mitochondrial carrier domain superfamily [IPR023395] | 14 | 21 | 2.987582 | 0.002812 | Q9HC21,Q9BSK2,Q9Y619,Q02978,Q9NZJ7,Q70HW3,Q9Y6C9,Q9H2D1,P12235,Q9UBX3,O43808,Q6NUK1,P12236,Q6KCM7 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 228,3,36,456,335,142,305,176,365,109,236,474,470,222 | 1723,236,1429,775,365,470,879,904,456,222,474,142,3,176,506,228,335,109,1226,36,305 | -0.15890258245488978,1.567220738704834,-0.0026102883160087067,0.45921398013028775,1.1151934116250275,0.9172078124078225,0.37235963057923405,0.3431478364322099,0.9439558302360769,1.6155716241957836,0.9172078124078225,2.0804411470022126,4.079438950901208,1.8521189098662278,0.8498533620967631,1.6035173065048012,1.2183796925819346,2.2684732013809596,0.1348936174475735,3.1453808033753354,1.2947135868342938 | 3,417 |
Proton transmembrane transporter activity | 13 | 36 | 2.954697 | 0.00313 | P00846,P24539,Q93050,P06576,P12235,Q7KZN9,O00400,Q9Y487,O75964,Q13423,P00403,P13073,O95202 | Functions | GO Molecular function | msigdb_gomf | 0,162,135,421,365,333,16,274,51,151,118,186,127 | 16,1379,1605,51,127,118,0,775,421,1312,1232,365,186,1928,600,2471,3286,162,759,2192,1000,979,2924,3201,779,731,843,1644,904,151,333,135,506,1457,274,738 | 3.5618203282976997,0.028199720326965952,-0.09593126943002946,2.902220138550719,2.1474202525907056,2.191697356585309,4.079438950901208,0.45921398013028775,1.010349571326269,0.07414127779889645,0.1197589134781991,1.1151934116250275,1.7937767070377697,-0.25452629436448265,0.6991742787236601,-0.5166796247488002,-1.3170501619437505,1.932936974823011,0.47357736156305924,-0.3842701148909007,0.2695373236736853,0.2843264501176428,-0.7899635190956561,-1.1119839097372366,0.45921398013028775,0.5164778220540673,0.4014404547791768,-0.11161663697128474,0.3431478364322099,1.9786763260210907,1.2183796925819346,2.1140159037622634,0.8498533620967631,-0.0026102883160087067,1.4323854934737215,0.5164778220540673 | 3,417 |
Endoplasmic reticulum organization | 22 | 50 | 2.937588 | 0.003308 | Q9NVV0,Q9P2W9,P49257,Q8N4V1,P57088,Q9H6H4,O14976,Q96A33,Q15041,O95197,Q8N5M9,Q15629,O43681,Q15363,Q8NHH9,Q9NQC3,Q9NPA0,Q00765,P46379,P61026,P49069,Q12981 | Processes and pathways | GO Biological process | msigdb_gobp | 645,4,650,14,271,279,400,284,160,37,296,42,549,46,175,68,220,604,226,354,618,249 | 1666,1427,1600,696,400,933,1040,549,1551,1554,37,2809,226,618,650,917,271,354,1259,604,829,249,816,160,2237,46,42,659,1190,1702,1569,14,296,2376,963,175,284,2713,1593,1223,1843,279,1486,220,68,645,1376,3386,1224,4 | -0.1273401837881595,-0.0026102883160087067,-0.09593126943002946,0.5590967396986621,1.0367189234918222,0.3138038545974289,0.23985743121252281,0.7817950089963721,-0.06467431361864844,-0.06467431361864844,3.1262526328104014,-0.7033078821496582,1.6035173065048012,0.6713991887930522,0.6295128244024532,0.32849244575329073,1.4323854934737215,1.1540796106437512,0.1045887365929969,0.6991742787236601,0.415932129064235,1.5185103694031445,0.43039150987620567,1.944401687938058,-0.4006732349357356,2.9810060001650047,3.1070691737442258,0.6154905133855352,0.14999301851452415,-0.14310210131811343,-0.06467431361864844,3.5707848317991115,1.3199613772518044,-0.46670653209308793,0.2990819080544139,1.8521189098662278,1.382657610013963,-0.6348148888478948,-0.080283891168658,0.1348936174475735,-0.2065373586035809,1.4075687949647808,-0.018070520659702844,1.6276038128114534,2.6600769622038456,0.6435049519950851,0.043549855895539176,-2.2103407897809766,0.1348936174475735,4.079438950901208 | 3,417 |
Sensorimotor neuropathy | 11 | 32 | 2.930641 | 0.003383 | P00846,P07602,Q5KU26,Q9Y2R0,P03886,O60313,P07196,Q9NZJ7,O95831,P00403,P05023 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,32,486,5,72,294,233,335,149,118,511 | 1600,1602,294,149,118,0,72,511,233,32,3084,2973,2291,1725,3072,2640,1562,2118,1673,3013,2201,1347,1389,486,555,687,1913,2919,1940,335,5,1273 | -0.09593126943002946,-0.09593126943002946,1.3199613772518044,2.012773197487723,2.191697356585309,4.079438950901208,2.598130352078956,0.8362984856412491,1.5793419482693727,3.202436833742072,-0.9310917159637686,-0.8249557647149923,-0.43360527729208703,-0.15890258245488978,-0.9132800387870509,-0.6008400388890252,-0.06467431361864844,-0.3515885852686711,-0.1273401837881595,-0.860139758826078,-0.3842701148909007,0.05886364960372865,0.028199720326965952,0.8903495429355509,0.7817950089963721,0.5732411343760665,-0.2384902973611259,-0.7725386334031646,-0.25452629436448265,1.2183796925819346,4.079438950901208,0.1045887365929969 | 3,417 |
Mitochondrial membrane organization | 23 | 53 | 2.927798 | 0.003414 | Q9NS69,Q16891,Q9Y584,Q9H3K2,Q9P0J0,Q9Y5J7,O60313,P0DP25,P17152,P62072,Q53H12,P45880,Q6UXV4,Q5XKP0,O60220,Q9Y5L4,Q9Y5J9,Q15070,Q13505,Q8N8Q8,P12235,O95202,O14737 | Processes and pathways | GO Biological process | msigdb_gobp | 19,529,30,33,419,164,294,303,434,56,443,60,449,198,460,477,347,100,105,108,365,127,255 | 2985,255,460,294,1063,2600,1492,127,2082,775,1690,2468,303,365,434,2843,1692,3086,3212,2334,60,1782,1317,917,903,56,828,105,100,529,1101,443,1005,198,449,678,2403,1835,108,1300,33,19,1154,546,419,1037,1549,1273,695,30,164,347,477 | -0.8425236583575074,1.481738356319479,0.9305955446314544,1.3199613772518044,0.22496634533860416,-0.583919668151991,-0.033567813428752,2.1474202525907056,-0.33530974411801295,0.45921398013028775,-0.14310210131811343,-0.5166796247488002,1.2947135868342938,1.1151934116250275,0.9838731573525725,-0.7205457694435239,-0.14310210131811343,-0.9310917159637686,-1.1303571839723463,-0.4501346415467144,2.751922092384719,-0.19062001449545884,0.07414127779889645,0.32849244575329073,0.3431478364322099,2.7923363998378443,0.415932129064235,2.301105245667895,2.3658887117772305,0.8091037855865696,0.2100409512222278,0.9705945223247175,0.2695373236736853,1.711216457757838,0.9572887845888515,0.5873548038204078,-0.4833211743492699,-0.2065373586035809,2.2684732013809596,0.08938291553650131,3.202436833742072,3.5258411651536656,0.180086585856304,0.7954637182819312,1.0235475745145948,0.25471437049160844,-0.049102349624348285,0.1045887365929969,0.5732411343760665,3.221347085581454,1.9214522256714823,1.1798756638524783,0.9172078124078225 | 3,417 |
Exocytic vesicle | 14 | 42 | 2.927113 | 0.003421 | P50897,P61026,O60499,P05067,Q92905,O43752,Q96A57,P0DP25,Q9UI14,O15400,Q9UEU0,O43760,Q92542,Q9BVK6 | Localization | GO Cellular component | msigdb_gocc | 1,354,39,359,300,141,79,303,125,250,381,285,351,352 | 1600,250,141,285,39,1090,479,359,1606,2258,303,751,1559,1313,709,699,2923,1,1067,2541,779,1643,1001,354,1644,1789,2731,1418,3039,1188,2271,1477,391,351,300,79,614,352,1079,381,125,2494 | -0.09593126943002946,1.5062759619135841,2.0804411470022126,1.3701663535448179,3.1166678348556403,0.2100409512222278,0.9037925174593933,1.1281812332227774,-0.09593126943002946,-0.41711821570494334,1.2947135868342938,0.48790903352268455,-0.06467431361864844,0.07414127779889645,0.5449214820360619,0.5590967396986621,-0.7899635190956561,4.079438950901208,0.22496634533860416,-0.5502118327072625,0.45921398013028775,-0.11161663697128474,0.2695373236736853,1.1540796106437512,-0.11161663697128474,-0.19062001449545884,-0.651869854997686,0.012813065246235574,-0.8778043387082375,0.14999301851452415,-0.41711821570494334,-0.018070520659702844,1.0629820996007722,1.1669903758343456,1.3073496705658783,2.5251175908152326,0.6853015617305336,1.1669903758343456,0.22496634533860416,1.0891399743619552,2.1695960214639096,-0.5166796247488002 | 3,417 |
Ascites | 10 | 31 | 2.919981 | 0.003501 | Q14108,P04062,Q13510,O43683,O15118,Q9NSD9,Q14739,O75787,P22413,Q06330 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 98,195,75,275,148,20,212,211,243,188 | 148,275,2967,772,211,1813,195,289,1777,2567,2671,243,3344,1582,2118,1344,2122,2065,1934,1240,442,1026,188,1141,75,98,212,2004,3251,20,793 | 2.012773197487723,1.4199889089821724,-0.8249557647149923,0.45921398013028775,1.6396139556611513,-0.2065373586035809,1.72307457356377,1.345112044634575,-0.19062001449545884,-0.5670436789350108,-0.617805031632897,1.5429108324741363,-1.5289120558488012,-0.080283891168658,-0.3515885852686711,0.05886364960372865,-0.3515885852686711,-0.3190719005092798,-0.25452629436448265,0.1197589134781991,0.9705945223247175,0.25471437049160844,1.7820457887243357,0.180086585856304,2.546060857024669,2.387342541189054,1.6396139556611513,-0.2867183612159623,-1.2043820778052585,3.5168159185133003,0.45921398013028775 | 3,417 |
Protein localization to endoplasmic reticulum | 12 | 39 | 2.911892 | 0.003592 | Q9Y5M8,Q96HY6,P46379,P61026,Q9NQC3,O15258,Q15629,O43681,P24390,O43731,Q13438,P51572 | Processes and pathways | GO Biological process | msigdb_gobp | 64,129,226,354,68,483,42,549,44,110,404,402 | 933,483,549,110,1551,2357,2603,1954,1023,44,551,2260,226,1385,402,1113,2702,1760,1697,1902,354,1259,404,830,2237,42,1190,1590,1741,129,834,1223,1627,68,1224,992,1663,708,64 | 0.3138038545974289,0.8903495429355509,0.7817950089963721,2.2575598483675283,-0.06467431361864844,-0.46670653209308793,-0.583919668151991,-0.27060224728382676,0.25471437049160844,3.000556997593149,0.7817950089963721,-0.41711821570494334,1.6035173065048012,0.028199720326965952,1.0367189234918222,0.1950810860549713,-0.6348148888478948,-0.17474182156354792,-0.14310210131811343,-0.2384902973611259,1.1540796106437512,0.1045887365929969,1.0367189234918222,0.415932129064235,-0.4006732349357356,3.1070691737442258,0.14999301851452415,-0.080283891168658,-0.15890258245488978,2.1474202525907056,0.415932129064235,0.1348936174475735,-0.09593126943002946,2.6600769622038456,0.1348936174475735,0.2843264501176428,-0.11161663697128474,0.5590967396986621,2.7316219936973174 | 3,417 |
Carboxylic acid transport | 11 | 34 | 2.903947 | 0.003685 | P07602,Q15041,Q9Y619,P30825,Q02978,O60831,Q9NZJ7,Q9UBX3,Q9H2D1,Q9H936,P14174 | Processes and pathways | GO Biological process | msigdb_gobp | 32,160,36,40,456,232,335,109,176,506,28 | 2353,2882,232,1429,2722,656,1409,952,32,1231,28,891,570,40,3072,879,827,1432,456,937,160,2237,2005,1970,846,769,176,1303,506,1572,335,109,1226,36 | -0.46670653209308793,-0.7551608870541102,1.5793419482693727,-0.0026102883160087067,-0.651869854997686,0.6154905133855352,0.012813065246235574,0.2990819080544139,3.202436833742072,0.1197589134781991,3.221347085581454,0.35777018045817044,0.7543711682631408,3.1070691737442258,-0.9132800387870509,0.37235963057923405,0.415932129064235,-0.0026102883160087067,0.9439558302360769,0.3138038545974289,1.944401687938058,-0.4006732349357356,-0.2867183612159623,-0.27060224728382676,0.4014404547791768,0.47357736156305924,1.8521189098662278,0.08938291553650131,0.8498533620967631,-0.06467431361864844,1.2183796925819346,2.2684732013809596,0.1348936174475735,3.1453808033753354 | 3,417 |
Recruitment of mitotic centrosome proteins and complexes | 14 | 35 | 2.891739 | 0.003831 | P07437,O95684,O75935,Q96CS2,O43805,Q9H6D7,Q15154,Q68CZ6,O94927,Q13561,P68371,Q9BSJ2,P41208,P04350 | Processes and pathways | Reactome Pathways | msigdb_reactome | 320,317,194,287,197,396,466,497,242,435,371,607,93,319 | 197,194,242,317,319,1091,320,1690,2025,2026,1383,93,1900,1642,1365,1932,1319,2891,371,620,435,2977,1047,2204,466,1243,497,2130,287,2736,607,396,1272,1596,1173 | 1.711216457757838,1.72307457356377,1.5429108324741363,1.256658100316569,1.256658100316569,0.2100409512222278,1.256658100316569,-0.14310210131811343,-0.3028748428550267,-0.3028748428550267,0.028199720326965952,2.4087268221913423,-0.2384902973611259,-0.11161663697128474,0.043549855895539176,-0.25452629436448265,0.07414127779889645,-0.7551608870541102,1.1021796941094018,0.6713991887930522,0.9838731573525725,-0.8249557647149923,0.23985743121252281,-0.3842701148909007,0.9305955446314544,0.1197589134781991,0.8633800839961283,-0.3515885852686711,1.3576511964696762,-0.651869854997686,0.6991742787236601,1.0498637286274306,0.1045887365929969,-0.080283891168658,0.165057285462392 | 3,417 |
Inorganic anion transport | 20 | 30 | 2.867879 | 0.004132 | P51797,P04920,P51798,P51790,O43681,P45880,P08183,P21796,Q15043,P0CG08,Q8TDW0,Q02978,Q9C0H2,Q9Y277,Q9UHG3,Q96S66,P54105,Q9UBX3,P22413,Q9Y6M7 | Processes and pathways | GO Biological process | msigdb_gobp | 639,900,403,779,549,60,323,69,326,824,846,456,202,76,205,346,859,109,243,646 | 2866,2882,549,900,323,824,69,243,1179,60,779,639,403,859,1432,904,456,326,1164,846,346,1373,202,1841,1488,109,205,76,3141,646 | -0.7378300187664318,-0.7551608870541102,0.7817950089963721,0.3431478364322099,1.2439235324069875,0.415932129064235,2.63949253044833,1.5429108324741363,0.14999301851452415,2.751922092384719,0.45921398013028775,0.6435049519950851,1.0367189234918222,0.38691633847751733,-0.0026102883160087067,0.3431478364322099,0.9439558302360769,1.2439235324069875,0.165057285462392,0.4014404547791768,1.1927355777835806,0.043549855895539176,1.6993368662863828,-0.2065373586035809,-0.018070520659702844,2.2684732013809596,1.6755129356232892,2.546060857024669,-0.9848254487759778,0.6435049519950851 | 3,417 |
Hydrolase activity acting on glycosyl bonds | 12 | 29 | 2.84664 | 0.004418 | P08236,P04062,P17900,Q9NUJ1,P54802,P06865,P10253,O60502,P33908,P16278,O75503,P06280 | Functions | GO Molecular function | msigdb_gomf | 289,195,134,231,103,422,170,174,551,376,315,383 | 1575,1576,174,315,195,1310,383,422,2184,289,170,1607,626,376,134,1526,2923,551,1384,103,1260,1026,1419,2679,1500,2652,2657,231,1662 | -0.080283891168658,-0.080283891168658,1.8521189098662278,1.2693678996019138,1.72307457356377,0.07414127779889645,1.0760741454068623,1.010349571326269,-0.3842701148909007,1.345112044634575,1.8753114211973756,-0.09593126943002946,0.6574670293566639,1.0891399743619552,2.1140159037622634,-0.049102349624348285,-0.7899635190956561,0.7817950089963721,0.028199720326965952,2.333576542930749,0.1045887365929969,0.25471437049160844,0.012813065246235574,-0.617805031632897,-0.033567813428752,-0.6008400388890252,-0.6008400388890252,1.5914407759518774,-0.11161663697128474 | 3,417 |
Anchoring of the basal body to the plasma membrane | 12 | 36 | 2.826042 | 0.004713 | P07437,O95684,O75935,Q96CS2,O43805,Q9H6D7,Q15154,O94927,Q13561,P68371,P41208,P04350 | Processes and pathways | Reactome Pathways | msigdb_reactome | 320,317,194,287,197,396,466,242,435,371,93,319 | 197,194,242,317,319,1091,320,1690,2025,2026,1383,93,1900,1642,1643,1365,1932,1319,2891,371,620,435,2977,1047,2204,1188,1145,466,1243,497,2130,2549,287,396,1272,1596 | 1.711216457757838,1.72307457356377,1.5429108324741363,1.256658100316569,1.256658100316569,0.2100409512222278,1.256658100316569,-0.14310210131811343,-0.3028748428550267,-0.3028748428550267,0.028199720326965952,2.4087268221913423,-0.2384902973611259,-0.11161663697128474,-0.11161663697128474,0.043549855895539176,-0.25452629436448265,0.07414127779889645,-0.7551608870541102,1.1021796941094018,0.6713991887930522,0.9838731573525725,-0.8249557647149923,0.23985743121252281,-0.3842701148909007,0.14999301851452415,0.180086585856304,0.9305955446314544,0.1197589134781991,0.8633800839961283,-0.3515885852686711,-0.5502118327072625,1.3576511964696762,1.0498637286274306,0.1045887365929969,-0.080283891168658 | 3,417 |
Aurka activation by tpx2 | 12 | 35 | 2.81083 | 0.004941 | P07437,O95684,O75935,Q96CS2,O43805,Q9H6D7,Q15154,O94927,Q13561,P68371,P41208,P04350 | Processes and pathways | Reactome Pathways | msigdb_reactome | 320,317,194,287,197,396,466,242,435,371,93,319 | 1334,197,1175,194,242,317,319,1091,320,1690,2025,2026,1383,93,1900,1642,1365,1932,1319,2891,371,620,435,2977,1047,2204,466,1243,497,2130,287,396,1272,1596,3079 | 0.05886364960372865,1.711216457757838,0.14999301851452415,1.72307457356377,1.5429108324741363,1.256658100316569,1.256658100316569,0.2100409512222278,1.256658100316569,-0.14310210131811343,-0.3028748428550267,-0.3028748428550267,0.028199720326965952,2.4087268221913423,-0.2384902973611259,-0.11161663697128474,0.043549855895539176,-0.25452629436448265,0.07414127779889645,-0.7551608870541102,1.1021796941094018,0.6713991887930522,0.9838731573525725,-0.8249557647149923,0.23985743121252281,-0.3842701148909007,0.9305955446314544,0.1197589134781991,0.8633800839961283,-0.3515885852686711,1.3576511964696762,1.0498637286274306,0.1045887365929969,-0.080283891168658,-0.9132800387870509 | 3,417 |
Metal ion transmembrane transporter activity | 11 | 28 | 2.796327 | 0.005169 | Q6P4Q7,Q15043,Q9UM00,P35670,P05023,Q8N4V1,Q9HD20,O95202,P16615,Q9Y6M7,Q9HC07 | Functions | GO Molecular function | msigdb_gomf | 487,326,623,394,511,14,145,127,413,646,31 | 127,511,2224,2503,2426,1231,413,1559,1780,394,1432,1259,1213,2034,326,487,14,1877,1880,1054,1373,1034,1303,31,145,645,623,646 | 2.1474202525907056,0.8362984856412491,-0.4006732349357356,-0.5334238928726274,-0.4999787955465205,0.1197589134781991,1.0235475745145948,-0.06467431361864844,-0.19062001449545884,1.0498637286274306,-0.0026102883160087067,0.1045887365929969,0.1348936174475735,-0.3028748428550267,1.2439235324069875,0.8903495429355509,3.5707848317991115,-0.22249405275792178,-0.22249405275792178,0.23985743121252281,0.043549855895539176,0.25471437049160844,0.08938291553650131,3.2118986899262745,2.0579624190940984,0.6435049519950851,0.6713991887930522,0.6435049519950851 | 3,417 |
Golgi cisterna | 15 | 28 | 2.794421 | 0.005199 | Q08379,O95249,Q9H4A6,Q10472,Q8NBN3,Q8WVQ1,Q10713,Q8NBZ7,Q8TBA6,Q15363,O00461,P51572,Q9BXS4,Q96JB2,Q96L58 | Localization | GO Cellular component | msigdb_gocc | 578,97,131,377,166,458,107,140,77,46,433,402,380,445,644 | 433,97,657,824,402,1213,3308,578,984,377,107,1824,2271,46,1500,166,140,77,1974,458,445,644,925,380,2138,131,1750,2495 | 0.9838731573525725,2.387342541189054,0.6154905133855352,0.415932129064235,1.0367189234918222,0.1348936174475735,-1.3741374478355866,0.7406157866680001,0.2843264501176428,1.0891399743619552,2.2902458390004905,-0.2065373586035809,-0.41711821570494334,2.9810060001650047,-0.033567813428752,1.9099473684040134,2.091651777071882,2.5355975253386704,-0.27060224728382676,0.9439558302360769,0.9705945223247175,0.6435049519950851,0.32849244575329073,1.0891399743619552,-0.3515885852686711,2.13630429417419,-0.15890258245488978,-0.5166796247488002 | 3,417 |
Tetrapyrrole binding | 10 | 18 | 2.787808 | 0.005307 | Q9H7Z7,O15173,Q8WUJ1,O43169,Q6UW02,P09601,P30519,Q7KZN9,O00264,Q16850 | Functions | GO Molecular function | msigdb_gomf | 261,7,297,9,172,11,13,333,89,58 | 89,7,9,1312,11,2058,13,431,58,172,333,297,1707,3064,2213,261,1425,1271 | 2.451288581048882,3.8170176474388193,3.808378367384122,0.07414127779889645,3.6154272920019888,-0.3190719005092798,3.579737287321298,0.9971248028613773,2.7721600981017382,1.8753114211973756,1.2183796925819346,1.3199613772518044,-0.14310210131811343,-0.8955176729308301,-0.3842701148909007,1.4694349811947218,0.012813065246235574,0.1045887365929969 | 3,417 |
Receptor | 13 | 32 | 2.775213 | 0.005517 | Q9GZP9,Q9BUN8,Q14108,Q9NUJ3,Q8WUM4,Q12959,P57105,O75787,P20645,Q567V2,Q13641,Q8WTV0,Q6NTF9 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 353,65,98,508,427,518,173,211,277,251,124,350,223 | 538,1754,2147,749,211,2780,2838,952,1956,277,1961,173,518,675,124,98,815,2897,251,223,2207,350,427,65,353,1713,1543,508,2660,2960,2385,1548 | 0.7954637182819312,-0.17474182156354792,-0.36790863721425243,0.48790903352268455,1.6396139556611513,-0.6861161020861396,-0.7205457694435239,0.2990819080544139,-0.27060224728382676,1.4075687949647808,-0.27060224728382676,1.8637254027658279,0.8227153339568873,0.5873548038204078,2.1695960214639096,2.387342541189054,0.43039150987620567,-0.7551608870541102,1.5062759619135841,1.6155716241957836,-0.3842701148909007,1.1669903758343456,1.010349571326269,2.7214485369137704,1.1669903758343456,-0.14310210131811343,-0.049102349624348285,0.8498533620967631,-0.6008400388890252,-0.8074358076237756,-0.46670653209308793,-0.049102349624348285 | 3,417 |
Abnormal biliary tract morphology | 9 | 23 | 2.763456 | 0.005719 | P07602,Q14108,P04062,Q5XKP0,Q10713,P09601,Q9NSD9,Q14739,P14174 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,98,195,198,107,11,20,212,28 | 549,502,195,32,11,28,2972,1994,1782,917,2118,107,1141,98,212,198,1396,847,20,335,850,1549,793 | 0.7817950089963721,0.8498533620967631,1.72307457356377,3.202436833742072,3.6154272920019888,3.221347085581454,-0.8249557647149923,-0.2867183612159623,-0.19062001449545884,0.32849244575329073,-0.3515885852686711,2.2902458390004905,0.180086585856304,2.387342541189054,1.6396139556611513,1.711216457757838,0.028199720326965952,0.4014404547791768,3.5168159185133003,1.2183796925819346,0.4014404547791768,-0.049102349624348285,0.45921398013028775 | 3,417 |
Golgi stack | 17 | 38 | 2.74874 | 0.005982 | Q08379,O95249,Q9H4A6,Q14789,Q10472,Q8NBN3,Q8WVQ1,Q10713,Q8NBZ7,Q8TBA6,Q15363,Q10469,O00461,P51572,Q9BXS4,Q96JB2,Q96L58 | Localization | GO Cellular component | msigdb_gocc | 578,97,131,356,377,166,458,107,140,77,46,464,433,402,380,445,644 | 433,2150,97,657,824,2086,402,1184,1213,1701,3308,578,464,984,377,107,1824,2002,356,2271,46,1500,166,140,77,1974,458,445,644,925,3096,380,2138,131,1750,931,2494,2495 | 0.9838731573525725,-0.36790863721425243,2.387342541189054,0.6154905133855352,0.415932129064235,-0.33530974411801295,1.0367189234918222,0.14999301851452415,0.1348936174475735,-0.14310210131811343,-1.3741374478355866,0.7406157866680001,0.9305955446314544,0.2843264501176428,1.0891399743619552,2.2902458390004905,-0.2065373586035809,-0.2867183612159623,1.14114326456016,-0.41711821570494334,2.9810060001650047,-0.033567813428752,1.9099473684040134,2.091651777071882,2.5355975253386704,-0.27060224728382676,0.9439558302360769,0.9705945223247175,0.6435049519950851,0.32849244575329073,-0.9310917159637686,1.0891399743619552,-0.3515885852686711,2.13630429417419,-0.15890258245488978,0.32849244575329073,-0.5166796247488002,-0.5166796247488002 | 3,417 |
Intrinsic component of endoplasmic reticulum membrane | 23 | 54 | 2.746873 | 0.006017 | Q9UBM7,Q8TCT9,Q8N4V1,P57088,Q86XL3,P51572,Q96A33,Q15041,Q15629,Q16799,O95470,Q6Y1H2,Q9BUN8,Q969X5,Q9NQC3,O75844,O00767,Q9Y282,Q8TB61,Q9NPA0,Q6NTF9,Q9GZP9,Q12981 | Localization | GO Cellular component | msigdb_gocc | 262,266,14,271,278,402,284,160,42,311,187,444,65,193,68,74,332,83,86,220,223,353,249 | 1666,332,1040,74,1090,187,1280,657,446,3178,856,2975,618,402,271,1259,2036,249,2397,816,160,42,311,659,223,444,1244,278,14,2376,941,86,266,1263,2169,193,284,2104,834,2713,65,353,1544,220,68,837,2691,3386,2771,262,623,83,568,2496 | -0.1273401837881595,1.2183796925819346,0.23985743121252281,2.546060857024669,0.2100409512222278,1.7820457887243357,0.08938291553650131,0.6154905133855352,0.9572887845888515,-1.075394715606791,0.38691633847751733,-0.8249557647149923,0.6713991887930522,1.0367189234918222,1.4323854934737215,0.1045887365929969,-0.3028748428550267,1.5185103694031445,-0.4833211743492699,0.43039150987620567,1.944401687938058,3.1070691737442258,1.2820530290453684,0.6154905133855352,1.6155716241957836,0.9705945223247175,0.1197589134781991,1.4075687949647808,3.5707848317991115,-0.46670653209308793,0.3138038545974289,2.4830307358799764,1.457108438974517,0.1045887365929969,-0.36790863721425243,1.7349112933227129,1.382657610013963,-0.33530974411801295,0.415932129064235,-0.6348148888478948,2.7214485369137704,1.1669903758343456,-0.049102349624348285,1.6276038128114534,2.6600769622038456,0.415932129064235,-0.617805031632897,-2.2103407897809766,-0.668970176567426,1.4694349811947218,0.6713991887930522,2.504107696101658,0.7680975338781076,-0.5166796247488002 | 3,417 |
Mitochondrial transmembrane transport | 26 | 53 | 2.734926 | 0.006239 | P00846,P25705,Q9BSK2,O95831,O60830,O95563,P24539,Q9Y619,Q8IYU8,P06576,Q6P4A7,Q9H2D1,O75964,Q99595,P21796,O14925,P23786,P12236,P56134,P12235,O43615,Q15388,Q9H936,Q96NB2,O75027,O95202 | Processes and pathways | GO Biological process | msigdb_gobp | 0,759,3,149,22,656,162,36,425,421,171,176,51,52,69,201,595,470,731,365,496,633,506,769,624,127 | 201,496,1723,22,624,2327,1429,1605,51,2600,127,656,149,1177,0,775,421,3225,365,470,1928,69,595,162,759,1000,3201,1431,879,731,843,904,633,1535,1101,171,425,1877,3252,1300,1054,769,52,835,3,176,506,1572,1660,1226,1016,1273,36 | 1.6993368662863828,0.8633800839961283,-0.15890258245488978,3.389160419925041,0.6574670293566639,-0.4501346415467144,-0.0026102883160087067,-0.09593126943002946,2.902220138550719,-0.583919668151991,2.1474202525907056,0.6154905133855352,2.012773197487723,0.14999301851452415,4.079438950901208,0.45921398013028775,1.010349571326269,-1.1487833229977529,1.1151934116250275,0.9172078124078225,-0.25452629436448265,2.63949253044833,0.7130174694629439,1.932936974823011,0.47357736156305924,0.2695373236736853,-1.1119839097372366,-0.0026102883160087067,0.37235963057923405,0.5164778220540673,0.4014404547791768,0.3431478364322099,0.6574670293566639,-0.049102349624348285,0.2100409512222278,1.8753114211973756,1.010349571326269,-0.22249405275792178,-1.2043820778052585,0.08938291553650131,0.23985743121252281,0.47357736156305924,2.8923057086966835,0.415932129064235,4.079438950901208,1.8521189098662278,0.8498533620967631,-0.06467431361864844,-0.11161663697128474,0.1348936174475735,0.2695373236736853,0.1045887365929969,3.1453808033753354 | 3,417 |
Steroid binding | 9 | 24 | 2.70956 | 0.006737 | Q14108,P04062,P21796,O15173,Q9H1P3,O95772,O15118,O00264,P45880 | Functions | GO Molecular function | msigdb_gomf | 98,195,69,7,204,80,148,89,60 | 89,148,7,2328,1950,80,195,511,2426,69,1993,1381,1179,617,337,60,1344,98,2244,2172,2802,691,204,869 | 2.451288581048882,2.012773197487723,3.8170176474388193,-0.4501346415467144,-0.27060224728382676,2.5146209992328776,1.72307457356377,0.8362984856412491,-0.4999787955465205,2.63949253044833,-0.2867183612159623,0.028199720326965952,0.14999301851452415,0.6713991887930522,1.2055702200831364,2.751922092384719,0.05886364960372865,2.387342541189054,-0.4006732349357356,-0.36790863721425243,-0.6861161020861396,0.5732411343760665,1.6874357190816478,0.38691633847751733 | 3,417 |
Organic acid transmembrane transport | 16 | 29 | 2.701501 | 0.006903 | Q15041,P31751,P08183,Q9Y619,P53985,Q8TDW0,P30825,Q02978,O60831,Q9UBX3,Q9H2D1,P23786,Q9H936,O95563,Q96NB2,P28288 | Processes and pathways | GO Biological process | msigdb_gobp | 160,760,323,36,827,846,40,456,232,109,176,595,506,656,769,570 | 1723,232,1429,2722,656,952,323,1231,595,570,40,760,1132,3072,1431,879,827,456,160,2005,846,769,176,1303,506,1572,109,1226,36 | -0.15890258245488978,1.5793419482693727,-0.0026102883160087067,-0.651869854997686,0.6154905133855352,0.2990819080544139,1.2439235324069875,0.1197589134781991,0.7130174694629439,0.7543711682631408,3.1070691737442258,0.47357736156305924,0.180086585856304,-0.9132800387870509,-0.0026102883160087067,0.37235963057923405,0.415932129064235,0.9439558302360769,1.944401687938058,-0.2867183612159623,0.4014404547791768,0.47357736156305924,1.8521189098662278,0.08938291553650131,0.8498533620967631,-0.06467431361864844,2.2684732013809596,0.1348936174475735,3.1453808033753354 | 3,417 |
Hormone metabolic process | 13 | 32 | 2.686614 | 0.007218 | Q8NBN7,P07711,Q9UBM7,Q969M3,Q53GQ0,Q6NUM9,O75844,P42892,Q9HB40,O75787,P07858,O95470,P05023 | Processes and pathways | GO Biological process | msigdb_gobp | 416,119,262,521,457,424,74,116,54,211,184,187,511 | 1603,211,74,2723,187,511,119,184,2945,2635,2389,540,1179,116,3270,2118,2337,1872,457,424,416,1393,1653,521,2381,3234,2767,54,944,262,1155,968 | -0.09593126943002946,1.6396139556611513,2.546060857024669,-0.651869854997686,1.7820457887243357,0.8362984856412491,2.191697356585309,1.8054866977683843,-0.8074358076237756,-0.6008400388890252,-0.4833211743492699,0.7954637182819312,0.14999301851452415,2.2137247694910855,-1.2792732028995302,-0.3515885852686711,-0.4501346415467144,-0.22249405275792178,0.9439558302360769,1.010349571326269,1.0235475745145948,0.028199720326965952,-0.11161663697128474,0.8227153339568873,-0.46670653209308793,-1.1672626402980968,-0.668970176567426,2.862473067400689,0.3138038545974289,1.4694349811947218,0.180086585856304,0.2990819080544139 | 3,417 |
Ventricular arrhythmia | 15 | 40 | 2.685108 | 0.007251 | P00846,P50402,P03886,P10253,P12235,P46976,P0DP25,P36871,P23786,P42892,P49748,P00403,P21912,P02545,Q9HD47 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,257,72,170,365,552,303,209,595,116,439,118,401,502,580 | 1723,1858,3054,118,0,502,72,1555,1337,658,303,170,365,876,1992,3144,1958,401,595,1207,209,1467,116,552,439,1582,1641,257,1240,2233,2161,1187,1505,753,1978,2009,2523,1010,580,807 | -0.15890258245488978,-0.22249405275792178,-0.8955176729308301,2.191697356585309,4.079438950901208,0.8498533620967631,2.598130352078956,-0.06467431361864844,0.05886364960372865,0.6154905133855352,1.2947135868342938,1.8753114211973756,1.1151934116250275,0.37235963057923405,-0.2867183612159623,-1.002837216956381,-0.27060224728382676,1.0367189234918222,0.7130174694629439,0.1348936174475735,1.651602135580465,-0.018070520659702844,2.2137247694910855,0.7817950089963721,0.9705945223247175,-0.080283891168658,-0.11161663697128474,1.481738356319479,0.1197589134781991,-0.4006732349357356,-0.36790863721425243,0.14999301851452415,-0.033567813428752,0.48790903352268455,-0.27060224728382676,-0.2867183612159623,-0.5334238928726274,0.2695373236736853,0.7406157866680001,0.44481874473177313 | 3,417 |
Cis golgi network | 11 | 20 | 2.682998 | 0.007297 | O95249,Q14789,Q9Y3A6,Q9NPR9,P24390,Q8TBA6,O43731,O00461,Q9UNK9,P49755,Q96JB2 | Localization | GO Cellular component | msigdb_gocc | 97,356,327,73,44,77,110,433,476,440,445 | 433,1277,110,97,44,901,440,1213,578,356,1100,1500,988,77,1974,1741,445,73,476,327 | 0.9838731573525725,0.08938291553650131,2.2575598483675283,2.387342541189054,3.000556997593149,0.3431478364322099,0.9705945223247175,0.1348936174475735,0.7406157866680001,1.14114326456016,0.2100409512222278,-0.033567813428752,0.2843264501176428,2.5355975253386704,-0.27060224728382676,-0.15890258245488978,0.9705945223247175,2.556507639828149,0.9172078124078225,1.2439235324069875 | 3,417 |
primary active transporter | 12 | 27 | 2.671257 | 0.007557 | Q9GZP9,Q9BUN8,Q9Y5J7,P35670,P05023,Q6P4A7,O75381,Q9NS69,Q15388,O60888,P16615,Q6NTF9 | Functions | Panther Protein class | panther_protein_class | 353,65,164,394,511,171,749,19,633,306,413,223 | 306,749,2600,1177,511,2224,1954,1204,413,1559,1780,394,1469,1113,1213,633,2005,223,171,769,65,353,1303,1572,1660,19,164 | 1.2820530290453684,0.48790903352268455,-0.583919668151991,0.14999301851452415,0.8362984856412491,-0.4006732349357356,-0.27060224728382676,0.1348936174475735,1.0235475745145948,-0.06467431361864844,-0.19062001449545884,1.0498637286274306,-0.018070520659702844,0.1950810860549713,0.1348936174475735,0.6574670293566639,-0.2867183612159623,1.6155716241957836,1.8753114211973756,0.47357736156305924,2.7214485369137704,1.1669903758343456,0.08938291553650131,-0.06467431361864844,-0.11161663697128474,3.5258411651536656,1.9214522256714823 | 3,417 |
Sphingolipid metabolism | 7 | 11 | 2.658721 | 0.007844 | P07602,P04062,P17900,Q16880,Q13510,Q16739,O95470 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 32,195,134,104,75,146,187 | 510,1602,187,195,32,134,210,75,146,104,837 | 0.8362984856412491,-0.09593126943002946,1.7820457887243357,1.72307457356377,3.202436833742072,2.1140159037622634,1.651602135580465,2.546060857024669,2.0466941864597326,2.333576542930749,0.415932129064235 | 3,417 |
Establishment of protein localization to mitochondrial membrane | 12 | 22 | 2.654992 | 0.007931 | Q9P0J0,Q9Y5J7,Q15070,Q8N8Q8,P0DP25,Q9Y5J9,Q9NS69,O60220,P62072,Q53H12,Q9Y584,O14737 | Processes and pathways | GO Biological process | msigdb_gobp | 419,164,100,108,303,347,19,460,56,443,30,255 | 2985,255,460,2600,1690,303,1692,3086,56,828,100,443,108,1300,19,419,1549,695,30,164,347,477 | -0.8425236583575074,1.481738356319479,0.9305955446314544,-0.583919668151991,-0.14310210131811343,1.2947135868342938,-0.14310210131811343,-0.9310917159637686,2.7923363998378443,0.415932129064235,2.3658887117772305,0.9705945223247175,2.2684732013809596,0.08938291553650131,3.5258411651536656,1.0235475745145948,-0.049102349624348285,0.5732411343760665,3.221347085581454,1.9214522256714823,1.1798756638524783,0.9172078124078225 | 3,417 |
Abnormality of head blood vessel | 10 | 30 | 2.651506 | 0.008013 | P00846,P07602,P17900,P10619,P03886,Q13510,Q9NZJ7,P22413,P16278,P21964 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,32,134,388,72,75,335,243,376,29 | 3032,2498,2466,0,72,422,32,2184,388,2604,376,134,891,29,243,1960,2790,2846,1615,2757,75,1189,1769,2826,2307,713,1596,335,2662,568 | -0.8778043387082375,-0.5334238928726274,-0.5166796247488002,4.079438950901208,2.598130352078956,1.010349571326269,3.202436833742072,-0.3842701148909007,1.0629820996007722,-0.583919668151991,1.0891399743619552,2.1140159037622634,0.35777018045817044,3.221347085581454,1.5429108324741363,-0.27060224728382676,-0.6861161020861396,-0.7205457694435239,-0.09593126943002946,-0.668970176567426,2.546060857024669,0.14999301851452415,-0.17474182156354792,-0.7033078821496582,-0.43360527729208703,0.5449214820360619,-0.080283891168658,1.2183796925819346,-0.6008400388890252,0.7680975338781076 | 3,417 |
Trans golgi network membrane | 10 | 34 | 2.64907 | 0.008071 | Q9NX62,O60499,P35670,P53365,P05067,O43752,P40616,O15127,P20645,Q9HC07 | Localization | GO Cellular component | msigdb_gocc | 292,39,394,203,359,141,423,180,277,31 | 740,180,2147,141,2324,39,359,1606,1956,699,277,394,423,203,2572,1183,1643,982,861,2644,2514,1475,2002,2271,3044,1879,445,1033,2138,1745,31,292,1087,2562 | 0.5022091395121904,1.8171758374827531,-0.36790863721425243,2.0804411470022126,-0.4501346415467144,3.1166678348556403,1.1281812332227774,-0.09593126943002946,-0.27060224728382676,0.5590967396986621,1.4075687949647808,1.0498637286274306,1.010349571326269,1.6874357190816478,-0.5670436789350108,0.14999301851452415,-0.11161663697128474,0.2843264501176428,0.38691633847751733,-0.6008400388890252,-0.5334238928726274,-0.018070520659702844,-0.2867183612159623,-0.41711821570494334,-0.8778043387082375,-0.22249405275792178,0.9705945223247175,0.25471437049160844,-0.3515885852686711,-0.15890258245488978,3.2118986899262745,1.3325488033230897,0.22496634533860416,-0.5502118327072625 | 3,417 |
Ion channel transport | 12 | 32 | 2.637768 | 0.008345 | Q13555,Q96PU5,Q93050,P35670,Q9C0H2,Q9HD20,Q9Y487,Q15904,P27105,P51798,P16615,P05023 | Processes and pathways | Reactome Pathways | msigdb_reactome | 512,67,135,394,202,145,274,634,244,403,413,511 | 511,2224,413,1559,2471,3286,1780,244,1413,394,979,2924,779,639,403,1469,1644,1213,2442,512,634,1164,135,67,1657,202,2105,145,1488,1457,274,738 | 0.8362984856412491,-0.4006732349357356,1.0235475745145948,-0.06467431361864844,-0.5166796247488002,-1.3170501619437505,-0.19062001449545884,1.5429108324741363,0.012813065246235574,1.0498637286274306,0.2843264501176428,-0.7899635190956561,0.45921398013028775,0.6435049519950851,1.0367189234918222,-0.018070520659702844,-0.11161663697128474,0.1348936174475735,-0.4999787955465205,0.8362984856412491,0.6574670293566639,0.165057285462392,2.1140159037622634,2.7010545612582533,-0.11161663697128474,1.6993368662863828,-0.33530974411801295,2.0579624190940984,-0.018070520659702844,-0.0026102883160087067,1.4323854934737215,0.5164778220540673 | 3,417 |
Arthralgia | 12 | 35 | 2.628287 | 0.008582 | Q96HY6,P35670,P28070,Q13510,Q9NZ08,Q15800,Q9Y4P3,P22413,P02545,P14174,P25054,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,394,139,75,270,304,568,243,502,28,286,383 | 932,972,1492,1280,502,383,28,1558,3145,243,286,139,1612,1960,394,2029,2088,1673,2757,1240,844,630,75,1189,304,1590,1769,2169,129,2139,270,2743,2662,2021,568 | 0.3138038545974289,0.2843264501176428,-0.033567813428752,0.08938291553650131,0.8498533620967631,1.0760741454068623,3.221347085581454,-0.06467431361864844,-1.002837216956381,1.5429108324741363,1.3576511964696762,2.091651777071882,-0.09593126943002946,-0.27060224728382676,1.0498637286274306,-0.3028748428550267,-0.33530974411801295,-0.1273401837881595,-0.668970176567426,0.1197589134781991,0.4014404547791768,0.6574670293566639,2.546060857024669,0.14999301851452415,1.2947135868342938,-0.080283891168658,-0.17474182156354792,-0.36790863721425243,2.1474202525907056,-0.3515885852686711,1.4447586398473278,-0.651869854997686,-0.6008400388890252,-0.2867183612159623,0.7680975338781076 | 3,417 |
Copii coated er to golgi transport vesicle | 18 | 38 | 2.628101 | 0.008586 | Q08379,Q969X5,P10321,Q9NR31,Q969M3,Q9Y3A6,P49257,P05067,O14653,Q9Y3B3,Q15363,Q9Y282,Q96RQ1,P53634,P49755,Q9UEU0,O95070,Q9BVK6 | Localization | GO Cellular component | msigdb_gocc | 578,193,446,560,521,327,650,359,358,537,46,83,276,527,440,381,216,352 | 358,933,2150,974,1041,1554,216,1951,3383,1280,657,359,446,650,440,527,2846,578,829,1295,1474,46,1390,919,2206,2095,521,193,276,352,1593,560,2772,381,83,327,537,852 | 1.1281812332227774,0.3138038545974289,-0.36790863721425243,0.2843264501176428,0.23985743121252281,-0.06467431361864844,1.6276038128114534,-0.27060224728382676,-2.102282743065307,0.08938291553650131,0.6154905133855352,1.1281812332227774,0.9572887845888515,0.6295128244024532,0.9705945223247175,0.8091037855865696,-0.7205457694435239,0.7406157866680001,0.415932129064235,0.08938291553650131,-0.018070520659702844,2.9810060001650047,0.028199720326965952,0.32849244575329073,-0.3842701148909007,-0.33530974411801295,0.8227153339568873,1.7349112933227129,1.4199889089821724,1.1669903758343456,-0.080283891168658,0.7817950089963721,-0.668970176567426,1.0891399743619552,2.504107696101658,1.2439235324069875,0.8091037855865696,0.4014404547791768 | 3,417 |
Carbohydrate derivative transport | 13 | 20 | 2.624103 | 0.008688 | P07602,Q9HC21,Q9NZJ7,P12235,O43808,O00400,Q08722,L0R6Q1,Q8TB61,Q6NUK1,Q96AA3,Q8WTV0,Q6KCM7 | Processes and pathways | GO Biological process | msigdb_gobp | 32,228,335,365,236,16,84,341,86,474,344,350,222 | 341,16,2882,236,775,32,365,470,3072,1344,84,222,474,86,846,350,344,770,228,335 | 1.1927355777835806,3.5618203282976997,-0.7551608870541102,1.567220738704834,0.45921398013028775,3.202436833742072,1.1151934116250275,0.9172078124078225,-0.9132800387870509,0.05886364960372865,2.493577626661402,1.6155716241957836,0.9172078124078225,2.4830307358799764,0.4014404547791768,1.1669903758343456,1.1927355777835806,0.47357736156305924,1.6035173065048012,1.2183796925819346 | 3,417 |
Anion transport | 31 | 75 | 2.623999 | 0.00869 | O00400,P51798,P14174,P07602,Q15041,Q9Y619,P30825,O43681,Q9H2D1,P45880,P08183,P21796,Q15043,Q02978,Q9C0H2,Q9Y277,Q9UHG3,Q9NZJ7,Q08722,Q8TB61,Q6NUK1,Q96S66,P12236,Q6KCM7,Q9HC21,O60831,P12235,Q9UBX3,O43808,P22413,Q9H936 | Processes and pathways | GO Biological process | msigdb_gobp | 16,403,28,32,160,36,40,549,176,60,323,69,326,456,202,76,205,335,84,86,474,346,470,222,228,232,365,109,236,243,506 | 2866,16,2353,2882,549,236,1577,232,1429,2722,656,1409,900,775,952,32,323,1231,824,365,470,28,891,69,243,570,1179,40,3072,60,779,639,403,879,827,859,1432,904,456,84,937,160,2237,326,2005,1477,1164,222,474,1970,86,846,769,346,770,1373,202,1841,176,1303,506,1572,228,1884,1488,335,109,205,1401,1226,76,1807,36,3141,646 | -0.7378300187664318,3.5618203282976997,-0.46670653209308793,-0.7551608870541102,0.7817950089963721,1.567220738704834,-0.080283891168658,1.5793419482693727,-0.0026102883160087067,-0.651869854997686,0.6154905133855352,0.012813065246235574,0.3431478364322099,0.45921398013028775,0.2990819080544139,3.202436833742072,1.2439235324069875,0.1197589134781991,0.415932129064235,1.1151934116250275,0.9172078124078225,3.221347085581454,0.35777018045817044,2.63949253044833,1.5429108324741363,0.7543711682631408,0.14999301851452415,3.1070691737442258,-0.9132800387870509,2.751922092384719,0.45921398013028775,0.6435049519950851,1.0367189234918222,0.37235963057923405,0.415932129064235,0.38691633847751733,-0.0026102883160087067,0.3431478364322099,0.9439558302360769,2.493577626661402,0.3138038545974289,1.944401687938058,-0.4006732349357356,1.2439235324069875,-0.2867183612159623,-0.018070520659702844,0.165057285462392,1.6155716241957836,0.9172078124078225,-0.27060224728382676,2.4830307358799764,0.4014404547791768,0.47357736156305924,1.1927355777835806,0.47357736156305924,0.043549855895539176,1.6993368662863828,-0.2065373586035809,1.8521189098662278,0.08938291553650131,0.8498533620967631,-0.06467431361864844,1.6035173065048012,-0.22249405275792178,-0.018070520659702844,1.2183796925819346,2.2684732013809596,1.6755129356232892,0.028199720326965952,0.1348936174475735,2.546060857024669,-0.19062001449545884,3.1453808033753354,-0.9848254487759778,0.6435049519950851 | 3,417 |
Receptor | 13 | 43 | 2.621481 | 0.008755 | Q9Y5M8,Q14108,O15173,P30825,P35613,P24390,O43731,Q9NS69,O15118,Q14739,O75787,P20645,O00264 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 64,98,7,40,298,44,110,19,148,212,211,277,89 | 89,3284,664,148,7,110,211,3035,952,1091,2945,2603,2024,1991,751,1956,2635,1525,277,44,2116,40,298,649,3369,1618,2396,98,815,212,1323,2005,486,350,1880,925,724,481,19,2660,2108,64,2593 | 2.451288581048882,-1.3170501619437505,0.6014378848555904,2.012773197487723,3.8170176474388193,2.2575598483675283,1.6396139556611513,-0.8778043387082375,0.2990819080544139,0.2100409512222278,-0.8074358076237756,-0.583919668151991,-0.3028748428550267,-0.2867183612159623,0.48790903352268455,-0.27060224728382676,-0.6008400388890252,-0.049102349624348285,1.4075687949647808,3.000556997593149,-0.3515885852686711,3.1070691737442258,1.3073496705658783,0.6295128244024532,-1.7887145493144427,-0.09593126943002946,-0.4833211743492699,2.387342541189054,0.43039150987620567,1.6396139556611513,0.07414127779889645,-0.2867183612159623,0.8903495429355509,1.1669903758343456,-0.22249405275792178,0.32849244575329073,0.5307152226992892,0.9037925174593933,3.5258411651536656,-0.6008400388890252,-0.33530974411801295,2.7316219936973174,-0.5670436789350108 | 3,417 |
Molecular transducer activity | 13 | 40 | 2.604288 | 0.009207 | Q9BUN8,Q99720,Q14108,Q6RW13,O15173,Q15629,Q9Y6I9,O15118,Q08722,O75787,P20645,Q9NRA0,Q8WTV0 | Functions | GO Molecular function | msigdb_gomf | 65,481,98,389,7,42,331,148,84,211,277,475,350 | 3284,664,148,7,211,952,2945,1956,1525,277,1092,2116,1179,980,1961,649,2029,2368,84,2396,98,1323,42,2005,881,486,2207,389,350,1880,834,925,481,65,475,1984,2660,2771,992,331 | -1.3170501619437505,0.6014378848555904,2.012773197487723,3.8170176474388193,1.6396139556611513,0.2990819080544139,-0.8074358076237756,-0.27060224728382676,-0.049102349624348285,1.4075687949647808,0.2100409512222278,-0.3515885852686711,0.14999301851452415,0.2843264501176428,-0.27060224728382676,0.6295128244024532,-0.3028748428550267,-0.46670653209308793,2.493577626661402,-0.4833211743492699,2.387342541189054,0.07414127779889645,3.1070691737442258,-0.2867183612159623,0.37235963057923405,0.8903495429355509,-0.3842701148909007,1.0629820996007722,1.1669903758343456,-0.22249405275792178,0.415932129064235,0.32849244575329073,0.9037925174593933,2.7214485369137704,0.9172078124078225,-0.27060224728382676,-0.6008400388890252,-0.668970176567426,0.2843264501176428,1.2311640964910526 | 3,417 |
Protein targeting to mitochondrion | 25 | 53 | 2.599574 | 0.009334 | P49257,Q9NS69,O95831,O60830,P51572,Q9Y584,Q9P0J0,Q9Y5J7,Q9Y3D6,Q9Y512,Q99595,P62072,Q53H12,O14925,O60220,Q9Y5L4,Q9Y5J9,P55786,Q8TB36,O95429,Q10713,O43615,Q15388,O00165,O14737 | Processes and pathways | GO Biological process | msigdb_gobp | 650,19,149,22,402,30,419,164,694,695,52,56,443,201,460,477,347,603,480,610,107,496,633,245,255 | 245,932,255,201,496,460,22,2327,2600,1492,610,697,149,1177,1690,3225,2115,1179,3086,650,1317,402,603,56,2476,107,937,633,2399,1101,443,1479,2067,480,2345,52,1624,3138,1079,1660,19,419,2049,2528,1037,1088,694,2142,695,30,164,347,477 | 1.5307219638457237,0.3138038545974289,1.481738356319479,1.6993368662863828,0.8633800839961283,0.9305955446314544,3.389160419925041,-0.4501346415467144,-0.583919668151991,-0.033567813428752,0.6853015617305336,0.5590967396986621,2.012773197487723,0.14999301851452415,-0.14310210131811343,-1.1487833229977529,-0.3515885852686711,0.14999301851452415,-0.9310917159637686,0.6295128244024532,0.07414127779889645,1.0367189234918222,0.6991742787236601,2.7923363998378443,-0.5166796247488002,2.2902458390004905,0.3138038545974289,0.6574670293566639,-0.4833211743492699,0.2100409512222278,0.9705945223247175,-0.018070520659702844,-0.3190719005092798,0.9037925174593933,-0.4501346415467144,2.8923057086966835,-0.09593126943002946,-0.9848254487759778,0.22496634533860416,-0.11161663697128474,3.5258411651536656,1.0235475745145948,-0.3028748428550267,-0.5334238928726274,0.25471437049160844,0.22496634533860416,0.5732411343760665,-0.3515885852686711,0.5732411343760665,3.221347085581454,1.9214522256714823,1.1798756638524783,0.9172078124078225 | 3,417 |
Cytochrome complex assembly | 9 | 13 | 2.589678 | 0.009607 | Q9BSK2,Q15070,Q9Y2R0,Q6DKK2,Q8N8Q8,P53701,Q7KZN9,Q69YU5,O75880 | Processes and pathways | GO Biological process | msigdb_gobp | 3,100,5,136,108,431,333,21,59 | 515,59,431,100,1006,21,136,333,108,1302,3,1549,5 | 0.8227153339568873,2.7620488324659895,0.9971248028613773,2.3658887117772305,0.2695373236736853,3.41672208839756,2.1028433404883855,1.2183796925819346,2.2684732013809596,0.08938291553650131,4.079438950901208,-0.049102349624348285,4.079438950901208 | 3,417 |
Paraparesis | 8 | 28 | 2.586108 | 0.009707 | P35637,Q9H6K4,P04062,Q9Y619,Q5XKP0,Q6DKK2,Q13510,O75787 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 384,34,195,36,198,136,75,211 | 211,2782,3143,195,891,401,2674,384,2539,1673,2293,2644,2369,1533,1439,1499,75,2822,198,136,1392,1299,34,1774,1517,1946,1273,36 | 1.6396139556611513,-0.6861161020861396,-1.002837216956381,1.72307457356377,0.35777018045817044,1.0367189234918222,-0.617805031632897,1.0760741454068623,-0.5502118327072625,-0.1273401837881595,-0.43360527729208703,-0.6008400388890252,-0.46670653209308793,-0.049102349624348285,-0.0026102883160087067,-0.033567813428752,2.546060857024669,-0.7033078821496582,1.711216457757838,2.1028433404883855,0.028199720326965952,0.08938291553650131,3.192961477567768,-0.17474182156354792,-0.033567813428752,-0.25452629436448265,0.1045887365929969,3.1453808033753354 | 3,417 |
Horizontal nystagmus | 8 | 23 | 2.585876 | 0.009713 | P00846,P07602,P04062,O60313,O14773,O95831,Q9H061,Q5HYK3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,32,195,294,206,149,23,247 | 2985,1600,206,294,1950,149,0,195,32,1255,491,917,1965,2119,2293,247,3132,1299,23,1940,1488,335,1155 | -0.8425236583575074,-0.09593126943002946,1.651602135580465,1.3199613772518044,-0.27060224728382676,2.012773197487723,4.079438950901208,1.72307457356377,3.202436833742072,0.1045887365929969,0.8768787712343713,0.32849244575329073,-0.27060224728382676,-0.3515885852686711,-0.43360527729208703,1.5307219638457237,-0.9848254487759778,0.08938291553650131,3.3707223205539893,-0.25452629436448265,-0.018070520659702844,1.2183796925819346,0.180086585856304 | 3,417 |
Endoplasmic reticulum tubular network organization | 6 | 11 | 2.568216 | 0.010222 | Q15041,Q9NQC3,O95197,Q8NHH9,P57088,Q9H6H4 | Processes and pathways | GO Biological process | msigdb_gobp | 160,68,37,175,271,279 | 37,271,354,160,2237,1702,175,1223,279,1486,68 | 3.1262526328104014,1.4323854934737215,1.1540796106437512,1.944401687938058,-0.4006732349357356,-0.14310210131811343,1.8521189098662278,0.1348936174475735,1.4075687949647808,-0.018070520659702844,2.6600769622038456 | 3,417 |
Ragged red muscle fibers | 6 | 19 | 2.541326 | 0.011043 | P00846,P03886,Q70HW3,Q9H2D1,O95831,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,72,142,176,149,118 | 974,1407,149,118,0,72,365,2674,1342,1870,1907,142,1911,2523,1541,176,1107,1549,1776 | 0.2843264501176428,0.012813065246235574,2.012773197487723,2.191697356585309,4.079438950901208,2.598130352078956,1.1151934116250275,-0.617805031632897,0.05886364960372865,-0.22249405275792178,-0.2384902973611259,2.0804411470022126,-0.2384902973611259,-0.5334238928726274,-0.049102349624348285,1.8521189098662278,0.2100409512222278,-0.049102349624348285,-0.17474182156354792 | 3,417 |
Slc mediated transmembrane transport | 9 | 22 | 2.535329 | 0.011234 | Q15043,P30825,P35613,P12235,Q70HW3,Q9UBX3,O00400,Q8TB61,P12236 | Processes and pathways | Reactome Pathways | msigdb_reactome | 326,40,298,365,142,109,16,86,470 | 16,900,775,1231,365,470,1413,40,298,1181,827,1432,326,2005,1970,142,86,770,1303,506,109,646 | 3.5618203282976997,0.3431478364322099,0.45921398013028775,0.1197589134781991,1.1151934116250275,0.9172078124078225,0.012813065246235574,3.1070691737442258,1.3073496705658783,0.14999301851452415,0.415932129064235,-0.0026102883160087067,1.2439235324069875,-0.2867183612159623,-0.27060224728382676,2.0804411470022126,2.4830307358799764,0.47357736156305924,0.08938291553650131,0.8498533620967631,2.2684732013809596,0.6435049519950851 | 3,417 |
Sensory neuropathy | 10 | 35 | 2.528969 | 0.01144 | P00846,Q15041,Q8IV08,P48643,P03886,O60313,O60220,O95831,Q15067,P00403 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,160,450,447,72,294,460,149,117,118 | 510,1602,460,1925,294,1950,1492,149,118,0,72,2697,1524,1580,700,2059,1045,1725,447,1067,639,1673,3013,2233,160,117,1702,450,3252,1913,801,2523,1152,1940,2594 | 0.8362984856412491,-0.09593126943002946,0.9305955446314544,-0.25452629436448265,1.3199613772518044,-0.27060224728382676,-0.033567813428752,2.012773197487723,2.191697356585309,4.079438950901208,2.598130352078956,-0.6348148888478948,-0.049102349624348285,-0.080283891168658,0.5590967396986621,-0.3190719005092798,0.23985743121252281,-0.15890258245488978,0.9572887845888515,0.22496634533860416,0.6435049519950851,-0.1273401837881595,-0.860139758826078,-0.4006732349357356,1.944401687938058,2.202720271552077,-0.14310210131811343,0.9572887845888515,-1.2043820778052585,-0.2384902973611259,0.44481874473177313,-0.5334238928726274,0.180086585856304,-0.25452629436448265,-0.5670436789350108 | 3,417 |
Glycosphingolipid metabolism | 10 | 17 | 2.525617 | 0.01155 | P07602,P04062,P17900,P10619,Q16880,Q13510,Q9NZJ7,Q16739,P16278,P06280 | Processes and pathways | Reactome Pathways | msigdb_reactome | 32,195,134,388,104,75,335,146,376,383 | 1666,549,195,383,422,32,2184,388,376,134,75,146,104,2069,2713,1376,335 | -0.1273401837881595,0.7817950089963721,1.72307457356377,1.0760741454068623,1.010349571326269,3.202436833742072,-0.3842701148909007,1.0629820996007722,1.0891399743619552,2.1140159037622634,2.546060857024669,2.0466941864597326,2.333576542930749,-0.3190719005092798,-0.6348148888478948,0.043549855895539176,1.2183796925819346 | 3,417 |
Regulation of cellular ph | 9 | 23 | 2.516368 | 0.011857 | Q05086,P50897,Q93050,Q9Y487,O75787,Q92544,O75503,Q8N511,Q9HC07 | Processes and pathways | GO Biological process | msigdb_gobp | 192,1,135,274,211,379,315,95,31 | 315,211,900,421,824,1465,1178,1,1067,779,1644,192,634,95,379,135,2009,31,1015,1457,274,3141,646 | 1.2693678996019138,1.6396139556611513,0.3431478364322099,1.010349571326269,0.415932129064235,-0.018070520659702844,0.14999301851452415,4.079438950901208,0.22496634533860416,0.45921398013028775,-0.11161663697128474,1.7349112933227129,0.6574670293566639,2.3980433462775825,1.0891399743619552,2.1140159037622634,-0.2867183612159623,3.2118986899262745,0.2695373236736853,-0.0026102883160087067,1.4323854934737215,-0.9848254487759778,0.6435049519950851 | 3,417 |
Regulation of ph | 9 | 23 | 2.516368 | 0.011857 | Q05086,P50897,Q93050,Q9Y487,O75787,Q92544,O75503,Q8N511,Q9HC07 | Processes and pathways | GO Biological process | msigdb_gobp | 192,1,135,274,211,379,315,95,31 | 315,211,900,421,824,1465,1178,1,1067,779,1644,192,634,95,379,135,2009,31,1015,1457,274,3141,646 | 1.2693678996019138,1.6396139556611513,0.3431478364322099,1.010349571326269,0.415932129064235,-0.018070520659702844,0.14999301851452415,4.079438950901208,0.22496634533860416,0.45921398013028775,-0.11161663697128474,1.7349112933227129,0.6574670293566639,2.3980433462775825,1.0891399743619552,2.1140159037622634,-0.2867183612159623,3.2118986899262745,0.2695373236736853,-0.0026102883160087067,1.4323854934737215,-0.9848254487759778,0.6435049519950851 | 3,417 |
Recruitment of numa to mitotic centrosomes | 16 | 40 | 2.51437 | 0.011925 | Q13885,O95684,P07437,Q96CS2,O75935,O43805,Q9BUF5,Q9H6D7,Q15154,Q68CZ6,O94927,Q13561,P68371,Q9BSJ2,P41208,P04350 | Processes and pathways | Reactome Pathways | msigdb_reactome | 579,317,320,287,194,197,459,396,466,497,242,435,371,607,93,319 | 197,194,242,317,319,1091,320,1690,2025,2026,1383,93,1900,1642,1365,1932,1319,2891,371,620,796,435,579,2977,1047,2204,3061,466,1243,497,2130,287,2736,607,459,745,396,1272,1596,1173 | 1.711216457757838,1.72307457356377,1.5429108324741363,1.256658100316569,1.256658100316569,0.2100409512222278,1.256658100316569,-0.14310210131811343,-0.3028748428550267,-0.3028748428550267,0.028199720326965952,2.4087268221913423,-0.2384902973611259,-0.11161663697128474,0.043549855895539176,-0.25452629436448265,0.07414127779889645,-0.7551608870541102,1.1021796941094018,0.6713991887930522,0.44481874473177313,0.9838731573525725,0.7406157866680001,-0.8249557647149923,0.23985743121252281,-0.3842701148909007,-0.8955176729308301,0.9305955446314544,0.1197589134781991,0.8633800839961283,-0.3515885852686711,1.3576511964696762,-0.651869854997686,0.6991742787236601,0.9439558302360769,0.5022091395121904,1.0498637286274306,0.1045887365929969,-0.080283891168658,0.165057285462392 | 3,417 |
Translocation | 17 | 55 | 2.495271 | 0.012586 | Q9Y5J7,Q9Y5L4,Q9BTX1,O14925,Q15629,P37198,Q8N1F7,O43615,Q9NS69,Q99595,O60220,O60830,Q8NFH4,P62072,Q9Y5J9,P41208,Q9Y584 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 164,477,363,201,42,491,368,496,19,52,460,22,219,56,347,93,30 | 1061,1306,201,1853,496,460,1856,22,749,2599,1204,1466,491,93,3302,1561,2292,1434,1113,2702,1259,1865,56,2122,1069,42,1101,797,893,368,2131,219,1445,499,1878,2133,3274,1301,1683,834,723,52,363,3153,1511,1512,1573,19,2771,1985,2692,30,164,347,477 | 0.22496634533860416,0.07414127779889645,1.6993368662863828,-0.22249405275792178,0.8633800839961283,0.9305955446314544,-0.22249405275792178,3.389160419925041,0.48790903352268455,-0.583919668151991,0.1348936174475735,-0.018070520659702844,0.8768787712343713,2.4087268221913423,-1.3550516474221492,-0.06467431361864844,-0.43360527729208703,-0.0026102883160087067,0.1950810860549713,-0.6348148888478948,0.1045887365929969,-0.22249405275792178,2.7923363998378443,-0.3515885852686711,0.22496634533860416,3.1070691737442258,0.2100409512222278,0.44481874473177313,0.35777018045817044,1.1151934116250275,-0.3515885852686711,1.6276038128114534,-0.0026102883160087067,0.8633800839961283,-0.22249405275792178,-0.3515885852686711,-1.2792732028995302,0.08938291553650131,-0.1273401837881595,0.415932129064235,0.5307152226992892,2.8923057086966835,1.1281812332227774,-1.002837216956381,-0.033567813428752,-0.033567813428752,-0.06467431361864844,3.5258411651536656,-0.668970176567426,-0.27060224728382676,-0.617805031632897,3.221347085581454,1.9214522256714823,1.1798756638524783,0.9172078124078225 | 3,417 |
Hypocholesterolemia | 6 | 7 | 2.487439 | 0.012867 | P07602,Q9UBM7,Q9NVI7,P37268,Q9NZJ7,Q15800 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,262,268,299,335,304 | 32,299,447,304,268,335,262 | 3.202436833742072,1.3073496705658783,0.9572887845888515,1.2947135868342938,1.457108438974517,1.2183796925819346,1.4694349811947218 | 3,417 |
Ventricular hypertrophy | 14 | 39 | 2.481885 | 0.013069 | Q9H9S5,P03886,O75844,P10253,P12235,P46976,P22413,P02545,O75787,Q6NUK1,P00403,P21912,O75880,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 386,72,74,170,365,552,243,502,211,474,118,401,59,383 | 932,1723,1063,211,74,59,1309,118,502,72,383,170,954,365,1065,401,243,595,2674,1384,979,2870,1725,1996,552,3013,983,1473,1419,676,474,1875,2900,1879,1978,3023,2523,386,807 | 0.3138038545974289,-0.15890258245488978,0.22496634533860416,1.6396139556611513,2.546060857024669,2.7620488324659895,0.07414127779889645,2.191697356585309,0.8498533620967631,2.598130352078956,1.0760741454068623,1.8753114211973756,0.2990819080544139,1.1151934116250275,0.22496634533860416,1.0367189234918222,1.5429108324741363,0.7130174694629439,-0.617805031632897,0.028199720326965952,0.2843264501176428,-0.7378300187664318,-0.15890258245488978,-0.2867183612159623,0.7817950089963721,-0.860139758826078,0.2843264501176428,-0.018070520659702844,0.012813065246235574,0.5873548038204078,0.9172078124078225,-0.22249405275792178,-0.7551608870541102,-0.22249405275792178,-0.27060224728382676,-0.860139758826078,-0.5334238928726274,1.0760741454068623,0.44481874473177313 | 3,417 |
Abnormal left ventricle morphology | 10 | 31 | 2.478534 | 0.013192 | Q9H9S5,P03886,P10253,P12235,O43683,O75787,P00403,P21912,O75880,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 386,72,170,365,275,211,118,401,59,383 | 932,275,2967,772,1063,211,59,118,72,383,170,365,1065,401,2674,1725,3013,983,2337,1473,1419,676,2004,474,1875,2900,1879,1978,2523,386,807 | 0.3138038545974289,1.4199889089821724,-0.8249557647149923,0.45921398013028775,0.22496634533860416,1.6396139556611513,2.7620488324659895,2.191697356585309,2.598130352078956,1.0760741454068623,1.8753114211973756,1.1151934116250275,0.22496634533860416,1.0367189234918222,-0.617805031632897,-0.15890258245488978,-0.860139758826078,0.2843264501176428,-0.4501346415467144,-0.018070520659702844,0.012813065246235574,0.5873548038204078,-0.2867183612159623,0.9172078124078225,-0.22249405275792178,-0.7551608870541102,-0.22249405275792178,-0.27060224728382676,-0.5334238928726274,1.0760741454068623,0.44481874473177313 | 3,417 |
Membrane lipid catabolic process | 7 | 11 | 2.472493 | 0.013417 | P50897,P04062,P17900,P06865,Q13510,O95470,P06280 | Processes and pathways | GO Biological process | msigdb_gobp | 1,195,134,422,75,187,383 | 187,195,1310,383,422,2184,134,1,75,482,1376 | 1.7820457887243357,1.72307457356377,0.07414127779889645,1.0760741454068623,1.010349571326269,-0.3842701148909007,2.1140159037622634,4.079438950901208,2.546060857024669,0.9037925174593933,0.043549855895539176 | 3,417 |
Cation transmembrane transporter activity | 37 | 76 | 2.470419 | 0.013496 | P00846,Q9NVV0,P25705,Q93050,P35670,Q70HW3,Q8N4V1,O00400,Q9HD20,Q9Y487,P05141,Q13423,P16615,Q9HC07,P24539,Q9Y619,P30825,P06576,O75964,P13073,Q15043,Q7KZN9,Q9Y5K8,P20674,P56134,Q9HC21,Q6P4Q7,Q9UM00,P12235,O43808,Q99808,Q9H936,P00403,Q96NB2,O95202,Q9Y6M7,P05023 | Functions | GO Molecular function | msigdb_gomf | 0,645,759,135,394,142,14,16,145,274,775,151,413,31,162,36,40,421,51,186,326,333,738,600,731,228,487,623,365,236,770,506,118,769,127,646,511 | 16,1379,1723,236,1605,51,127,118,0,511,2224,775,421,2503,2426,1231,1312,1232,365,186,413,1928,1559,600,2471,3286,1780,162,759,40,2192,394,1000,979,2924,3201,779,1432,731,843,1644,1259,1213,904,2034,151,326,2005,1164,487,882,142,333,14,1877,1880,135,1054,769,770,1373,1034,1303,506,1572,31,228,145,645,1488,1457,623,274,738,36,646 | 3.5618203282976997,0.028199720326965952,-0.15890258245488978,1.567220738704834,-0.09593126943002946,2.902220138550719,2.1474202525907056,2.191697356585309,4.079438950901208,0.8362984856412491,-0.4006732349357356,0.45921398013028775,1.010349571326269,-0.5334238928726274,-0.4999787955465205,0.1197589134781991,0.07414127779889645,0.1197589134781991,1.1151934116250275,1.7937767070377697,1.0235475745145948,-0.25452629436448265,-0.06467431361864844,0.6991742787236601,-0.5166796247488002,-1.3170501619437505,-0.19062001449545884,1.932936974823011,0.47357736156305924,3.1070691737442258,-0.3842701148909007,1.0498637286274306,0.2695373236736853,0.2843264501176428,-0.7899635190956561,-1.1119839097372366,0.45921398013028775,-0.0026102883160087067,0.5164778220540673,0.4014404547791768,-0.11161663697128474,0.1045887365929969,0.1348936174475735,0.3431478364322099,-0.3028748428550267,1.9786763260210907,1.2439235324069875,-0.2867183612159623,0.165057285462392,0.8903495429355509,0.37235963057923405,2.0804411470022126,1.2183796925819346,3.5707848317991115,-0.22249405275792178,-0.22249405275792178,2.1140159037622634,0.23985743121252281,0.47357736156305924,0.47357736156305924,0.043549855895539176,0.25471437049160844,0.08938291553650131,0.8498533620967631,-0.06467431361864844,3.2118986899262745,1.6035173065048012,2.0579624190940984,0.6435049519950851,-0.018070520659702844,-0.0026102883160087067,0.6713991887930522,1.4323854934737215,0.5164778220540673,3.1453808033753354,0.6435049519950851 | 3,417 |
Abnormal retinal artery morphology | 10 | 26 | 2.461085 | 0.013852 | P00846,P07602,P17900,P10619,P03886,Q13510,Q9NZJ7,P22413,P16278,P21964 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,32,134,388,72,75,335,243,376,29 | 3032,2466,0,72,422,32,2184,388,2604,376,134,29,243,1960,2846,1615,2757,75,1189,1769,2826,2307,713,335,2662,568 | -0.8778043387082375,-0.5166796247488002,4.079438950901208,2.598130352078956,1.010349571326269,3.202436833742072,-0.3842701148909007,1.0629820996007722,-0.583919668151991,1.0891399743619552,2.1140159037622634,3.221347085581454,1.5429108324741363,-0.27060224728382676,-0.7205457694435239,-0.09593126943002946,-0.668970176567426,2.546060857024669,0.14999301851452415,-0.17474182156354792,-0.7033078821496582,-0.43360527729208703,0.5449214820360619,1.2183796925819346,-0.6008400388890252,0.7680975338781076 | 3,417 |
Hydrolase activity hydrolyzing o glycosyl compounds | 10 | 22 | 2.460674 | 0.013868 | P08236,P04062,P17900,Q9NUJ1,P54802,P06865,P10253,O60502,P16278,P06280 | Functions | GO Molecular function | msigdb_gomf | 289,195,134,231,103,422,170,174,376,383 | 1575,174,195,1310,383,422,2184,289,170,376,134,551,1384,103,1026,1419,2679,1500,2652,2657,231,1662 | -0.080283891168658,1.8521189098662278,1.72307457356377,0.07414127779889645,1.0760741454068623,1.010349571326269,-0.3842701148909007,1.345112044634575,1.8753114211973756,1.0891399743619552,2.1140159037622634,0.7817950089963721,0.028199720326965952,2.333576542930749,0.25471437049160844,0.012813065246235574,-0.617805031632897,-0.033567813428752,-0.6008400388890252,-0.6008400388890252,1.5914407759518774,-0.11161663697128474 | 3,417 |
Mitochondrial nucleotide transporter subfamily | 8 | 10 | 2.452034 | 0.014205 | Q9HC21,Q9BSK2,P12235,Q70HW3,O43808,Q9H2D1,Q6NUK1,Q6KCM7 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 228,3,365,142,236,176,474,222 | 236,775,365,470,222,474,142,3,176,228 | 1.567220738704834,0.45921398013028775,1.1151934116250275,0.9172078124078225,1.6155716241957836,0.9172078124078225,2.0804411470022126,4.079438950901208,1.8521189098662278,1.6035173065048012 | 3,417 |
Vacuolar lumen | 27 | 68 | 2.434719 | 0.014903 | P50897,Q9H7Z7,P17900,P10619,P53634,Q8NHP8,P07602,P08236,P06865,O43681,P10253,P07858,P11117,P07437,Q8IV08,P04062,Q13510,Q9NZJ7,O14773,P38435,Q9UMR5,Q14108,P54802,P68371,P16278,P07711,P06280 | Localization | GO Cellular component | msigdb_gocc | 1,261,134,388,527,158,32,289,422,549,170,184,189,320,450,195,75,335,206,337,82,98,103,371,376,119,383 | 1333,729,1575,206,549,995,195,1310,383,422,2503,320,32,2184,119,184,1690,289,170,388,189,2427,2428,876,915,376,134,1493,1178,2974,1093,337,3344,552,2607,1,2889,2364,1495,527,1364,103,1673,1931,1344,371,628,2512,1347,75,98,2204,450,2406,158,1104,1124,2766,1509,722,2739,2657,1354,261,1629,335,82,2806 | 0.05886364960372865,0.5164778220540673,-0.080283891168658,1.651602135580465,0.7817950089963721,0.2695373236736853,1.72307457356377,0.07414127779889645,1.0760741454068623,1.010349571326269,-0.5334238928726274,1.256658100316569,3.202436833742072,-0.3842701148909007,2.191697356585309,1.8054866977683843,-0.14310210131811343,1.345112044634575,1.8753114211973756,1.0629820996007722,1.7702938658351084,-0.4999787955465205,-0.4999787955465205,0.37235963057923405,0.32849244575329073,1.0891399743619552,2.1140159037622634,-0.033567813428752,0.14999301851452415,-0.8249557647149923,0.2100409512222278,1.2055702200831364,-1.5289120558488012,0.7817950089963721,-0.583919668151991,4.079438950901208,-0.7551608870541102,-0.46670653209308793,-0.033567813428752,0.8091037855865696,0.043549855895539176,2.333576542930749,-0.1273401837881595,-0.25452629436448265,0.05886364960372865,1.1021796941094018,0.6574670293566639,-0.5334238928726274,0.05886364960372865,2.546060857024669,2.387342541189054,-0.3842701148909007,0.9572887845888515,-0.4833211743492699,1.9558464367057236,0.2100409512222278,0.1950810860549713,-0.668970176567426,-0.033567813428752,0.5307152226992892,-0.651869854997686,-0.6008400388890252,0.05886364960372865,1.4694349811947218,-0.09593126943002946,1.2183796925819346,2.504107696101658,-0.6861161020861396 | 3,417 |
Arthritis | 15 | 45 | 2.426308 | 0.015253 | Q96HY6,Q14108,P04062,P10321,P35670,P28070,Q8WVQ1,Q13510,Q9NZ08,O75844,Q14739,P51798,P14174,P21964,P06280 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 129,98,195,446,394,139,458,75,270,74,212,403,28,29,383 | 932,3032,972,74,2565,1280,502,195,383,2535,446,2988,28,29,3145,139,394,2029,1288,403,2088,2846,1615,2293,1259,1701,630,75,98,212,2927,1705,2900,1590,458,2826,2307,129,801,1712,2139,270,1127,2021,1946 | 0.3138038545974289,-0.8778043387082375,0.2843264501176428,2.546060857024669,-0.5670436789350108,0.08938291553650131,0.8498533620967631,1.72307457356377,1.0760741454068623,-0.5502118327072625,0.9572887845888515,-0.8425236583575074,3.221347085581454,3.221347085581454,-1.002837216956381,2.091651777071882,1.0498637286274306,-0.3028748428550267,0.08938291553650131,1.0367189234918222,-0.33530974411801295,-0.7205457694435239,-0.09593126943002946,-0.43360527729208703,0.1045887365929969,-0.14310210131811343,0.6574670293566639,2.546060857024669,2.387342541189054,1.6396139556611513,-0.7899635190956561,-0.14310210131811343,-0.7551608870541102,-0.080283891168658,0.9439558302360769,-0.7033078821496582,-0.43360527729208703,2.1474202525907056,0.44481874473177313,-0.14310210131811343,-0.3515885852686711,1.4447586398473278,0.1950810860549713,-0.2867183612159623,-0.25452629436448265 | 3,417 |
Frequent falls | 12 | 39 | 2.426098 | 0.015262 | P00846,P07602,Q9H9S5,P04062,Q5THJ4,Q13510,O43819,Q9NZJ7,P12235,P37198,O75787,P21912 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,32,386,195,555,75,515,335,365,491,211,401 | 549,515,1811,974,211,1492,0,195,647,32,954,365,401,998,2674,491,1725,1562,879,1673,3013,2293,2336,1870,75,2204,1647,555,3132,2239,1976,1450,2523,1107,386,1774,335,1015,1776 | 0.7817950089963721,0.8227153339568873,-0.2065373586035809,0.2843264501176428,1.6396139556611513,-0.033567813428752,4.079438950901208,1.72307457356377,0.6295128244024532,3.202436833742072,0.2990819080544139,1.1151934116250275,1.0367189234918222,0.2695373236736853,-0.617805031632897,0.8768787712343713,-0.15890258245488978,-0.06467431361864844,0.37235963057923405,-0.1273401837881595,-0.860139758826078,-0.43360527729208703,-0.4501346415467144,-0.22249405275792178,2.546060857024669,-0.3842701148909007,-0.11161663697128474,0.7817950089963721,-0.9848254487759778,-0.4006732349357356,-0.27060224728382676,-0.0026102883160087067,-0.5334238928726274,0.2100409512222278,1.0760741454068623,-0.17474182156354792,1.2183796925819346,0.2695373236736853,-0.17474182156354792 | 3,417 |
Cardiac conduction abnormality | 12 | 30 | 2.423845 | 0.015357 | P00846,P50402,P06280,P03886,O43819,P46976,P0DP25,P49748,P00403,P21912,P02545,Q9HD47 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,257,383,72,515,552,303,439,118,401,502,580 | 1723,515,1858,2696,118,0,502,72,1555,383,303,1992,1958,401,595,2674,979,2924,552,439,257,2995,2337,1187,1647,766,753,1010,2246,580 | -0.15890258245488978,0.8227153339568873,-0.22249405275792178,-0.6348148888478948,2.191697356585309,4.079438950901208,0.8498533620967631,2.598130352078956,-0.06467431361864844,1.0760741454068623,1.2947135868342938,-0.2867183612159623,-0.27060224728382676,1.0367189234918222,0.7130174694629439,-0.617805031632897,0.2843264501176428,-0.7899635190956561,0.7817950089963721,0.9705945223247175,1.481738356319479,-0.8425236583575074,-0.4501346415467144,0.14999301851452415,-0.11161663697128474,0.47357736156305924,0.48790903352268455,0.2695373236736853,-0.4006732349357356,0.7406157866680001 | 3,417 |
Protein transmembrane transport | 9 | 25 | 2.419997 | 0.015521 | O14925,Q15629,Q9NS69,Q99595,O95831,O60830,Q07820,P49755,Q9Y584 | Processes and pathways | GO Biological process | msigdb_gobp | 201,42,19,52,149,22,463,440,30 | 201,496,22,749,2600,149,1177,3225,760,440,917,1113,2702,1902,1259,463,633,42,1101,834,52,1660,19,992,30 | 1.6993368662863828,0.8633800839961283,3.389160419925041,0.48790903352268455,-0.583919668151991,2.012773197487723,0.14999301851452415,-1.1487833229977529,0.47357736156305924,0.9705945223247175,0.32849244575329073,0.1950810860549713,-0.6348148888478948,-0.2384902973611259,0.1045887365929969,0.9305955446314544,0.6574670293566639,3.1070691737442258,0.2100409512222278,0.415932129064235,2.8923057086966835,-0.11161663697128474,3.5258411651536656,0.2843264501176428,3.221347085581454 | 3,417 |
Passive transmembrane transporter activity | 19 | 39 | 2.413235 | 0.015812 | P00846,Q9NVV0,P51797,P25705,P51798,P51790,P24539,P06576,O75964,P45880,Q07812,P21796,P0CG08,Q8TDW0,Q9C0H2,Q9Y277,Q96S66,P56134,Q9UM00 | Functions | GO Molecular function | msigdb_gomf | 0,645,639,759,403,779,162,421,51,60,828,69,824,846,202,76,346,731,623 | 2866,1605,51,1177,0,421,2503,2426,824,1928,69,162,759,1000,2924,60,3201,779,639,403,731,843,1259,2034,828,1164,1877,846,1880,1054,346,1624,1078,202,645,1488,623,76,3141 | -0.7378300187664318,-0.09593126943002946,2.902220138550719,0.14999301851452415,4.079438950901208,1.010349571326269,-0.5334238928726274,-0.4999787955465205,0.415932129064235,-0.25452629436448265,2.63949253044833,1.932936974823011,0.47357736156305924,0.2695373236736853,-0.7899635190956561,2.751922092384719,-1.1119839097372366,0.45921398013028775,0.6435049519950851,1.0367189234918222,0.5164778220540673,0.4014404547791768,0.1045887365929969,-0.3028748428550267,0.415932129064235,0.165057285462392,-0.22249405275792178,0.4014404547791768,-0.22249405275792178,0.23985743121252281,1.1927355777835806,-0.09593126943002946,0.22496634533860416,1.6993368662863828,0.6435049519950851,-0.018070520659702844,0.6713991887930522,2.546060857024669,-0.9848254487759778 | 3,417 |
Bulbar signs | 10 | 13 | 2.411802 | 0.015874 | P07602,Q99720,P35637,P04062,P00846,Q15043,P03886,Q9Y263,O43681,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,481,384,195,0,326,72,106,549,335 | 549,0,72,195,647,32,384,1340,326,1913,481,335,106 | 0.7817950089963721,4.079438950901208,2.598130352078956,1.72307457356377,0.6295128244024532,3.202436833742072,1.0760741454068623,0.05886364960372865,1.2439235324069875,-0.2384902973611259,0.9037925174593933,1.2183796925819346,2.301105245667895 | 3,417 |
Polyneuropathy | 8 | 22 | 2.401153 | 0.016344 | P00846,P07602,Q15041,Q9HC21,P03886,O60313,Q9NZJ7,O95831 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,32,160,228,72,294,335,149 | 294,516,149,2839,0,72,1310,32,1579,891,2192,394,1782,2640,1293,160,1389,1830,687,228,335,2743 | 1.3199613772518044,0.8227153339568873,2.012773197487723,-0.7205457694435239,4.079438950901208,2.598130352078956,0.07414127779889645,3.202436833742072,-0.080283891168658,0.35777018045817044,-0.3842701148909007,1.0498637286274306,-0.19062001449545884,-0.6008400388890252,0.08938291553650131,1.944401687938058,0.028199720326965952,-0.2065373586035809,0.5732411343760665,1.6035173065048012,1.2183796925819346,-0.651869854997686 | 3,417 |
Respirasome | 18 | 42 | 2.39869 | 0.016454 | Q9P0J0,Q9Y6M9,P51970,O43674,Q6DKK2,P13073,P03886,Q96CU9,O95299,O95139,Q7KZN9,P14406,Q13423,O95168,P21912,O43676,P00403,P22695 | Localization | GO Cellular component | msigdb_gocc | 419,524,577,229,136,186,72,395,420,207,333,49,151,561,401,25,118,185 | 3295,1753,1379,229,25,1812,1858,748,839,1335,207,561,3370,420,889,118,72,1312,1955,1232,186,49,1898,1253,3247,600,401,185,3280,2674,2192,3271,577,151,2759,1369,136,333,395,419,1549,524 | -1.3360226676213207,-0.17474182156354792,0.028199720326965952,1.5914407759518774,3.2777569763908665,-0.2065373586035809,-0.22249405275792178,0.48790903352268455,0.4014404547791768,0.05886364960372865,1.651602135580465,0.7680975338781076,-1.8091450547166552,1.010349571326269,0.35777018045817044,2.191697356585309,2.598130352078956,0.07414127779889645,-0.27060224728382676,0.1197589134781991,1.7937767070377697,2.9417301538561795,-0.2384902973611259,0.1045887365929969,-1.2043820778052585,0.6991742787236601,1.0367189234918222,1.8054866977683843,-1.2981337870876661,-0.617805031632897,-0.3842701148909007,-1.2792732028995302,0.7406157866680001,1.9786763260210907,-0.668970176567426,0.043549855895539176,2.1028433404883855,1.2183796925819346,1.0498637286274306,1.0235475745145948,-0.049102349624348285,0.8227153339568873 | 3,417 |
mitochondrial carrier protein | 6 | 8 | 2.385301 | 0.017065 | Q9HC21,Q9BSK2,Q9NZJ7,Q70HW3,Q9Y6C9,Q6KCM7 | Functions | Panther Protein class | panther_protein_class | 228,3,335,142,305,222 | 904,222,474,142,3,228,335,305 | 0.3431478364322099,1.6155716241957836,0.9172078124078225,2.0804411470022126,4.079438950901208,1.6035173065048012,1.2183796925819346,1.2947135868342938 | 3,417 |
Regulation of plk1 activity at g2 m transition | 12 | 40 | 2.381225 | 0.017255 | P07437,O95684,O75935,Q96CS2,O43805,Q9H6D7,Q15154,O94927,Q13561,P68371,P41208,P04350 | Processes and pathways | Reactome Pathways | msigdb_reactome | 320,317,194,287,197,396,466,242,435,371,93,319 | 1334,2322,197,194,242,2256,317,319,1091,320,1690,1814,2025,2026,1383,93,1900,1642,1643,1365,1932,2995,1319,2891,1727,371,620,435,2202,2977,1047,2204,466,1243,497,2130,287,396,1272,1596 | 0.05886364960372865,-0.4501346415467144,1.711216457757838,1.72307457356377,1.5429108324741363,-0.41711821570494334,1.256658100316569,1.256658100316569,0.2100409512222278,1.256658100316569,-0.14310210131811343,-0.2065373586035809,-0.3028748428550267,-0.3028748428550267,0.028199720326965952,2.4087268221913423,-0.2384902973611259,-0.11161663697128474,-0.11161663697128474,0.043549855895539176,-0.25452629436448265,-0.8425236583575074,0.07414127779889645,-0.7551608870541102,-0.15890258245488978,1.1021796941094018,0.6713991887930522,0.9838731573525725,-0.3842701148909007,-0.8249557647149923,0.23985743121252281,-0.3842701148909007,0.9305955446314544,0.1197589134781991,0.8633800839961283,-0.3515885852686711,1.3576511964696762,1.0498637286274306,0.1045887365929969,-0.080283891168658 | 3,417 |
Endoplasmic reticulum golgi intermediate compartment | 24 | 56 | 2.373866 | 0.017603 | Q9Y3B3,Q96RQ1,P53634,P51572,P61019,P24390,Q15363,P33908,P49755,Q08379,Q969X5,Q02818,P80303,Q9Y3A6,Q9Y282,O95070,Q8N511,Q9BVK6,Q14789,O15258,O14653,Q15904,Q10472,Q9H0U4 | Localization | GO Cellular component | msigdb_gocc | 537,276,527,402,541,44,46,551,440,578,193,325,70,327,83,216,95,352,356,483,358,634,377,253 | 358,483,2667,758,1041,216,1380,1637,44,3178,901,551,650,440,2435,402,2949,527,1364,541,70,325,2036,578,377,829,1295,1474,356,2680,46,1100,634,2206,2095,883,95,1741,2342,2168,193,1839,799,276,820,352,253,1593,2589,2020,1015,83,327,537,2022,852 | 1.1281812332227774,0.8903495429355509,-0.617805031632897,0.47357736156305924,0.23985743121252281,1.6276038128114534,0.028199720326965952,-0.11161663697128474,3.000556997593149,-1.075394715606791,0.3431478364322099,0.7817950089963721,0.6295128244024532,0.9705945223247175,-0.4999787955465205,1.0367189234918222,-0.8074358076237756,0.8091037855865696,0.043549855895539176,0.7954637182819312,2.63949253044833,1.2439235324069875,-0.3028748428550267,0.7406157866680001,1.0891399743619552,0.415932129064235,0.08938291553650131,-0.018070520659702844,1.14114326456016,-0.617805031632897,2.9810060001650047,0.2100409512222278,0.6574670293566639,-0.3842701148909007,-0.33530974411801295,0.37235963057923405,2.3980433462775825,-0.15890258245488978,-0.4501346415467144,-0.36790863721425243,1.7349112933227129,-0.2065373586035809,0.44481874473177313,1.4199889089821724,0.43039150987620567,1.1669903758343456,1.4940186536364441,-0.080283891168658,-0.5670436789350108,-0.2867183612159623,0.2695373236736853,2.504107696101658,1.2439235324069875,0.8091037855865696,-0.2867183612159623,0.4014404547791768 | 3,417 |
Impaired proprioception | 7 | 39 | 2.372157 | 0.017685 | P00846,Q9H6K4,Q9Y619,P54802,P07196,O14773,O00400 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,34,36,103,233,206,16 | 245,16,206,2498,515,1950,1492,0,2602,233,3225,3084,1580,1255,2291,3124,3072,103,2119,1673,1765,1868,862,619,1347,1389,2401,555,1830,450,1392,1299,801,2523,1152,34,1155,36,2594 | 1.5307219638457237,3.5618203282976997,1.651602135580465,-0.5334238928726274,0.8227153339568873,-0.27060224728382676,-0.033567813428752,4.079438950901208,-0.583919668151991,1.5793419482693727,-1.1487833229977529,-0.9310917159637686,-0.080283891168658,0.1045887365929969,-0.43360527729208703,-0.9848254487759778,-0.9132800387870509,2.333576542930749,-0.3515885852686711,-0.1273401837881595,-0.17474182156354792,-0.22249405275792178,0.38691633847751733,0.6713991887930522,0.05886364960372865,0.028199720326965952,-0.4833211743492699,0.7817950089963721,-0.2065373586035809,0.9572887845888515,0.028199720326965952,0.08938291553650131,0.44481874473177313,-0.5334238928726274,0.180086585856304,3.192961477567768,0.180086585856304,3.1453808033753354,-0.5670436789350108 | 3,417 |
EF-Hand 1, calcium-binding site [IPR018247] | 12 | 39 | 2.371283 | 0.017726 | O43852,Q14257,Q9NWM8,Q02818,P80303,Q9BRK5,Q9Y680,P0DP25,O95302,P43304,P41208,O95202 | Sequence | InterPro Binding site | interpro_binding_site | 256,227,196,325,70,169,411,303,307,338,93,127 | 1278,256,974,1429,127,307,2697,303,935,3373,2567,3010,2470,1413,1611,93,2229,338,70,325,2233,1143,227,2612,1568,474,2403,1835,1195,1008,835,169,1011,1269,196,1515,2772,823,411 | 0.08938291553650131,1.481738356319479,0.2843264501176428,-0.0026102883160087067,2.1474202525907056,1.2820530290453684,-0.6348148888478948,1.2947135868342938,0.3138038545974289,-1.8708329390666887,-0.5670436789350108,-0.860139758826078,-0.5166796247488002,0.012813065246235574,-0.09593126943002946,2.4087268221913423,-0.4006732349357356,1.2055702200831364,2.63949253044833,1.2439235324069875,-0.4006732349357356,0.180086585856304,1.6035173065048012,-0.583919668151991,-0.06467431361864844,0.9172078124078225,-0.4833211743492699,-0.2065373586035809,0.14999301851452415,0.2695373236736853,0.415932129064235,1.8984223305480457,0.2695373236736853,0.1045887365929969,1.72307457356377,-0.033567813428752,-0.668970176567426,0.43039150987620567,1.0367189234918222 | 3,417 |
Active ion transmembrane transporter activity | 18 | 45 | 2.366911 | 0.017937 | P12236,Q15043,Q02978,P35670,P06576,P12235,P20674,Q7KZN9,O00400,Q9HD20,Q9H936,P51798,P00403,P13073,O95202,P16615,Q9Y6M7,P05023 | Functions | GO Molecular function | msigdb_gomf | 470,326,456,394,421,365,600,333,16,145,506,403,118,186,127,413,646,511 | 16,1379,2882,127,118,900,511,2224,775,421,1231,1312,1232,365,470,186,413,1559,600,2471,3286,1780,2192,394,979,2924,3072,779,639,403,879,1432,1644,1213,904,456,326,333,1373,1303,506,145,1457,738,646 | 3.5618203282976997,0.028199720326965952,-0.7551608870541102,2.1474202525907056,2.191697356585309,0.3431478364322099,0.8362984856412491,-0.4006732349357356,0.45921398013028775,1.010349571326269,0.1197589134781991,0.07414127779889645,0.1197589134781991,1.1151934116250275,0.9172078124078225,1.7937767070377697,1.0235475745145948,-0.06467431361864844,0.6991742787236601,-0.5166796247488002,-1.3170501619437505,-0.19062001449545884,-0.3842701148909007,1.0498637286274306,0.2843264501176428,-0.7899635190956561,-0.9132800387870509,0.45921398013028775,0.6435049519950851,1.0367189234918222,0.37235963057923405,-0.0026102883160087067,-0.11161663697128474,0.1348936174475735,0.3431478364322099,0.9439558302360769,1.2439235324069875,1.2183796925819346,0.043549855895539176,0.08938291553650131,0.8498533620967631,2.0579624190940984,-0.0026102883160087067,0.5164778220540673,0.6435049519950851 | 3,417 |
calmodulin-related | 7 | 13 | 2.363226 | 0.018117 | O43852,Q14257,Q02818,P80303,Q9BRK5,P0DP25,P41208 | Functions | Panther Protein class | panther_protein_class | 256,227,325,70,169,303,93 | 256,303,1413,1611,93,2925,70,325,227,1568,425,835,169 | 1.481738356319479,1.2947135868342938,0.012813065246235574,-0.09593126943002946,2.4087268221913423,-0.7899635190956561,2.63949253044833,1.2439235324069875,1.6035173065048012,-0.06467431361864844,1.010349571326269,0.415932129064235,1.8984223305480457 | 3,417 |
Abnormal peripheral myelination | 8 | 31 | 2.35575 | 0.018485 | P00846,Q8TB36,P07602,P03886,P07196,Q9NZJ7,P02545,O15269 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 0,480,32,72,233,335,502,510 | 510,549,1925,1492,3054,0,502,72,233,32,2430,1580,1255,2059,2507,1111,1067,1293,2201,1418,2401,480,1708,1913,2765,801,1152,2105,335,1514,2594 | 0.8362984856412491,0.7817950089963721,-0.25452629436448265,-0.033567813428752,-0.8955176729308301,4.079438950901208,0.8498533620967631,2.598130352078956,1.5793419482693727,3.202436833742072,-0.4999787955465205,-0.080283891168658,0.1045887365929969,-0.3190719005092798,-0.5334238928726274,0.1950810860549713,0.22496634533860416,0.08938291553650131,-0.3842701148909007,0.012813065246235574,-0.4833211743492699,0.9037925174593933,-0.14310210131811343,-0.2384902973611259,-0.668970176567426,0.44481874473177313,0.180086585856304,-0.33530974411801295,1.2183796925819346,-0.033567813428752,-0.5670436789350108 | 3,417 |
Abnormal chorioretinal morphology | 10 | 32 | 2.351073 | 0.018719 | Q9H9S5,O14936,Q9Y619,Q96J42,Q5XKP0,Q10713,Q12768,P40855,P53701,O60826 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 386,539,36,200,198,107,619,237,431,592 | 539,973,1925,592,749,2151,2839,2783,657,2814,1612,237,1725,1467,1582,917,2436,431,1293,1701,107,619,815,198,1350,2009,200,386,1596,1545,1173,36 | 0.7954637182819312,0.2843264501176428,-0.25452629436448265,0.7130174694629439,0.48790903352268455,-0.36790863721425243,-0.7205457694435239,-0.6861161020861396,0.6154905133855352,-0.7033078821496582,-0.09593126943002946,1.567220738704834,-0.15890258245488978,-0.018070520659702844,-0.080283891168658,0.32849244575329073,-0.4999787955465205,0.9971248028613773,0.08938291553650131,-0.14310210131811343,2.2902458390004905,0.6713991887930522,0.43039150987620567,1.711216457757838,0.05886364960372865,-0.2867183612159623,1.711216457757838,1.0760741454068623,-0.080283891168658,-0.049102349624348285,0.165057285462392,3.1453808033753354 | 3,417 |
Secondary active transmembrane transporter activity | 16 | 24 | 2.350112 | 0.018768 | P51797,P53985,Q15043,Q02978,P12235,P04920,Q9UBX3,O00400,P05141,P53007,Q9H936,P51798,P51790,P12236,Q9Y6M7,O95202 | Functions | GO Molecular function | msigdb_gomf | 639,827,326,456,365,900,109,16,775,879,506,403,779,470,646,127 | 16,127,900,775,1231,365,470,3072,779,639,403,879,827,1432,904,456,326,2005,1877,1373,1303,506,109,646 | 3.5618203282976997,2.1474202525907056,0.3431478364322099,0.45921398013028775,0.1197589134781991,1.1151934116250275,0.9172078124078225,-0.9132800387870509,0.45921398013028775,0.6435049519950851,1.0367189234918222,0.37235963057923405,0.415932129064235,-0.0026102883160087067,0.3431478364322099,0.9439558302360769,1.2439235324069875,-0.2867183612159623,-0.22249405275792178,0.043549855895539176,0.08938291553650131,0.8498533620967631,2.2684732013809596,0.6435049519950851 | 3,417 |
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