term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Mitochondrial long chain fatty acid betaoxidation
7
14
2.210125
0.027096
P11310,P33121,O43772,Q9BY49,P50416,P49748,P23786
Processes and pathways
WikiPathways
msigdb_wp
526,477,7,104,205,270,21
7,1800,1522,526,1115,21,477,1119,2072,270,205,2310,573,104
4.226018188191668,-0.3470483341672869,-0.11936330150629972,0.6209579322675355,0.16703565837514714,3.2499231036709753,0.6809767597202617,0.16703565837514714,-0.6266292131087098,0.9651090844820442,1.0719930390626526,-0.9645295957870479,0.5905162575930732,1.443505472014357
2,627
F-type and V-type ATPases
7
15
2.20302
0.027593
Q9Y5K8,P21281,P61421,Q93050,P21283,Q9Y487,P38606
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
470,68,353,110,204,60,564
1461,1201,68,204,638,1929,1076,564,1377,1257,353,110,2090,60,470
-0.08248931576184856,0.09727763420498443,1.8386183095727955,1.0719930390626526,0.5287400095236409,-0.46502998509312093,0.20145406996397797,0.5905162575930732,-0.009661828907107638,0.06193809871766158,0.826227405842966,1.3964114253159658,-0.6266292131087098,1.9401901392777496,0.7105647803483593
2,627
Dna replication
37
85
2.202872
0.027604
P27694,P48556,Q9Y619,O43242,P25788,Q96DE5,P24941,Q13309,P12004,Q9UJX4,P33991,O00231,P28070,Q9UJX6,Q9BRT9,Q9UL46,Q9UJX2,P61289,P63208,P49721,P25789,Q99436,P28072,P33992,P41440,P60900,P20618,Q9H1A4,O60684,Q9UJX3,P25787,Q9NR33,P51530,P28074,Q14691,P40938,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
757,501,131,752,374,137,10,133,636,413,639,391,26,158,437,176,703,534,681,50,424,327,58,673,62,567,193,620,445,84,714,93,234,99,609,349,351
391,1102,1957,1143,2095,752,445,1614,2065,636,1529,2443,1995,1575,193,10,1771,1306,714,374,424,757,1204,26,58,99,1074,1367,639,673,831,1370,2102,759,2579,1624,2171,1155,349,62,877,501,1475,351,50,1628,234,2138,1375,2281,567,534,1633,1261,1675,1635,681,1900,937,988,1167,133,2238,837,609,1169,2316,802,1171,137,327,2014,437,1138,620,93,703,84,413,158,176,909,1017,1236,131
0.7689240696654053,0.16703565837514714,-0.5049701777237011,0.13231016688164354,-0.6677949340288234,0.43378138483021883,0.7105647803483593,-0.1940315756095389,-0.6266292131087098,0.5287400095236409,-0.11936330150629972,-1.2762621894424164,-0.54521680207282,-0.15654406682019772,1.098160443332041,3.8637936648459883,-0.30833420641619774,0.026291598449343083,0.46574171914072615,0.79770532131495,0.7398788632872855,0.43378138483021883,0.09727763420498443,2.9873822734682727,1.9601213162571827,1.5128628531871786,0.20145406996397797,-0.009661828907107638,0.5287400095236409,0.49739460823615383,0.3689385488367404,-0.009661828907107638,-0.6677949340288234,0.43378138483021883,-2.1466576685027245,-0.1940315756095389,-0.7510452441427796,0.13231016688164354,0.826227405842966,1.8999495008402818,0.33605613026518444,0.6511095956652878,-0.08248931576184856,0.826227405842966,2.1341018975806274,-0.1940315756095389,1.019001430589399,-0.7092669551263342,-0.009661828907107638,-0.9212204426655155,0.5905162575930732,0.6209579322675355,-0.1940315756095389,0.06193809871766158,-0.23182579208405982,-0.1940315756095389,0.49739460823615383,-0.42539625771276474,0.3028664327170777,0.2693694967580888,0.13231016688164354,1.2755271358920077,-0.8355204981110397,0.3689385488367404,0.5597788975631283,0.13231016688164354,-0.9645295957870479,0.4015136474761193,0.13231016688164354,1.2755271358920077,0.8825125816733365,-0.54521680207282,0.7398788632872855,0.16703565837514714,0.5597788975631283,1.625197139203179,0.49739460823615383,1.6690424559695667,0.7689240696654053,1.2007234515640317,1.1498563962326593,0.33605613026518444,0.2693694967580888,0.09727763420498443,1.3000750023293999
2,627
Ros and rns production in phagocytes
7
9
2.199735
0.027826
Q9Y5K8,P21281,P36543,P61421,Q93050,P21283,Q9Y487
Processes and pathways
Reactome Pathways
msigdb_reactome
470,68,283,353,110,204,60
68,204,283,564,353,110,2090,60,470
1.8386183095727955,1.0719930390626526,0.9378153921915153,0.5905162575930732,0.826227405842966,1.3964114253159658,-0.6266292131087098,1.9401901392777496,0.7105647803483593
2,627
Endopeptidase activity
25
52
2.188349
0.028644
Q8TCT9,Q9BYT8,O43464,P28070,O75844,P42892,O43847,P49721,P25789,Q99436,P28072,Q93009,Q16740,O75439,P60900,P20618,P28074,P52888,P49720,P42575,P54578,Q86UV5,Q96K76,Q99797,O14773
Functions
GO Molecular function
msigdb_gomf
543,282,261,26,520,43,418,50,424,327,58,461,65,317,567,193,99,236,351,232,479,385,126,510,366
366,261,418,317,520,1028,2409,193,597,424,26,58,99,1470,2101,1308,232,43,1080,676,351,50,236,1897,479,567,2233,2559,796,1678,2313,992,65,946,767,1327,385,543,1436,892,1597,461,126,1913,327,1495,510,1283,282,1791,1237,1562
0.79770532131495,0.9651090844820442,0.7398788632872855,0.8825125816733365,0.6209579322675355,0.23556536257123337,-1.1856659423599307,1.098160443332041,0.5597788975631283,0.7398788632872855,2.9873822734682727,1.9601213162571827,1.5128628531871786,-0.08248931576184856,-0.6677949340288234,0.026291598449343083,1.019001430589399,2.245025739511523,0.20145406996397797,0.49739460823615383,0.826227405842966,2.1341018975806274,1.019001430589399,-0.42539625771276474,0.6809767597202617,0.5905162575930732,-0.8355204981110397,-1.8455246823784321,0.4015136474761193,-0.23182579208405982,-0.9645295957870479,0.2693694967580888,1.879636801363511,0.3028664327170777,0.43378138483021883,0.026291598449343083,0.79770532131495,0.6209579322675355,-0.045922145989749696,0.33605613026518444,-0.15654406682019772,0.7105647803483593,1.3244345085536795,-0.42539625771276474,0.8825125816733365,-0.08248931576184856,0.6511095956652878,0.06193809871766158,0.9651090844820442,-0.30833420641619774,0.09727763420498443,-0.11936330150629972
2,627
Contractures of the joints of the upper limbs
9
54
2.188321
0.028646
Q99720,P37268,Q9Y619,Q86V48,Q9NR77,P42892,Q15392,Q96AY3,P23786
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
1,2,131,136,38,43,15,16,21
1609,443,1563,751,706,1924,520,1615,1841,524,268,970,2305,1891,21,1073,1669,1806,760,2,2260,43,641,2107,600,1376,428,1380,1853,797,798,2287,2315,402,15,611,2416,136,891,2377,617,580,16,2123,1054,1,1870,852,2152,38,158,1561,2440,131
-0.1940315756095389,0.7105647803483593,-0.15654406682019772,0.43378138483021883,0.46574171914072615,-0.46502998509312093,0.6209579322675355,-0.1940315756095389,-0.38606902938103327,0.6209579322675355,0.9651090844820442,0.2693694967580888,-0.9645295957870479,-0.42539625771276474,3.2499231036709753,0.20145406996397797,-0.23182579208405982,-0.3470483341672869,0.43378138483021883,4.83909130728241,-0.8782173997475797,2.245025739511523,0.5287400095236409,-0.6677949340288234,0.5597788975631283,-0.009661828907107638,0.7398788632872855,-0.009661828907107638,-0.38606902938103327,0.4015136474761193,0.4015136474761193,-0.9212204426655155,-0.9645295957870479,0.7689240696654053,3.5894737616308254,0.5597788975631283,-1.1856659423599307,1.2755271358920077,0.33605613026518444,-1.096293408964537,0.5597788975631283,0.5905162575930732,3.5292476415142087,-0.6677949340288234,0.23556536257123337,5.731242825625463,-0.38606902938103327,0.3689385488367404,-0.7092669551263342,2.5563715220078684,1.2007234515640317,-0.11936330150629972,-1.2308111164972735,1.3000750023293999
2,627
Abnormality of upper limb joint
11
80
2.18637
0.028789
P37268,P16278,Q9Y619,Q86V48,Q9NR77,P42892,Q15392,Q96AY3,P23786,O95831,O96028
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,64,131,136,38,43,15,16,21,89,63
1102,1609,443,1563,751,1764,706,1924,1989,2096,520,1615,1925,89,63,1841,524,1110,64,268,970,2305,1891,1365,21,1073,1669,1806,759,1308,2,2260,43,641,2107,600,1376,428,719,1813,1380,1544,1853,399,430,797,2143,798,2287,2315,402,2317,1170,941,15,2320,611,2416,136,891,2377,617,580,16,2123,1054,897,1870,852,2152,620,38,2450,158,2369,1561,2440,1190,661,131
0.16703565837514714,-0.1940315756095389,0.7105647803483593,-0.15654406682019772,0.43378138483021883,-0.30833420641619774,0.46574171914072615,-0.46502998509312093,-0.54521680207282,-0.6677949340288234,0.6209579322675355,-0.1940315756095389,-0.46502998509312093,1.625197139203179,1.879636801363511,-0.38606902938103327,0.6209579322675355,0.16703565837514714,1.879636801363511,0.9651090844820442,0.2693694967580888,-0.9645295957870479,-0.42539625771276474,-0.009661828907107638,3.2499231036709753,0.20145406996397797,-0.23182579208405982,-0.3470483341672869,0.43378138483021883,0.026291598449343083,4.83909130728241,-0.8782173997475797,2.245025739511523,0.5287400095236409,-0.6677949340288234,0.5597788975631283,-0.009661828907107638,0.7398788632872855,0.46574171914072615,-0.3470483341672869,-0.009661828907107638,-0.11936330150629972,-0.38606902938103327,0.7689240696654053,0.7398788632872855,0.4015136474761193,-0.7092669551263342,0.4015136474761193,-0.9212204426655155,-0.9645295957870479,0.7689240696654053,-0.9645295957870479,0.13231016688164354,0.3028664327170777,3.5894737616308254,-0.9645295957870479,0.5597788975631283,-1.1856659423599307,1.2755271358920077,0.33605613026518444,-1.096293408964537,0.5597788975631283,0.5905162575930732,3.5292476415142087,-0.6677949340288234,0.23556536257123337,0.33605613026518444,-0.38606902938103327,0.3689385488367404,-0.7092669551263342,0.5597788975631283,2.5563715220078684,-1.2762621894424164,1.2007234515640317,-1.052066109456029,-0.11936330150629972,-1.2308111164972735,0.13231016688164354,0.5287400095236409,1.3000750023293999
2,627
Secondary alcohol metabolic process
12
35
2.185828
0.028828
P48449,Q16850,P37268,O75874,O15118,Q15392,P48735,Q9UBM7,P49748,P04062,P16435,Q8WTV0
Processes and pathways
GO Biological process
msigdb_gobp
32,33,2,318,315,15,79,83,270,111,268,29
315,2025,318,2063,1615,923,111,1886,1304,268,1892,499,2,350,32,79,270,1584,1125,478,1421,2336,1815,836,457,800,2318,15,648,33,29,2379,1980,83,1396
0.8825125816733365,-0.5857698248713581,0.8825125816733365,-0.6266292131087098,-0.1940315756095389,0.3028664327170777,1.3725999294111904,-0.42539625771276474,0.026291598449343083,0.9651090844820442,-0.42539625771276474,0.6511095956652878,4.83909130728241,0.826227405842966,2.779137843232317,1.6907404652879743,0.9651090844820442,-0.15654406682019772,0.16703565837514714,0.6809767597202617,-0.045922145989749696,-1.008144828260293,-0.3470483341672869,0.3689385488367404,0.7105647803483593,0.4015136474761193,-0.9645295957870479,3.5894737616308254,0.5287400095236409,2.7637309800172836,2.870051204998666,-1.096293408964537,-0.5049701777237011,1.6690424559695667,-0.009661828907107638
2,627
Positive regulation of macroautophagy
6
14
2.1766
0.02951
P08754,P12235,P42858,P21796,Q9Y371,Q9H2M9
Processes and pathways
GO Biological process
msigdb_gobp
562,527,531,42,46,551
1239,633,1567,1246,1465,562,870,527,42,1531,531,1782,551,46
0.06193809871766158,0.5287400095236409,-0.15654406682019772,0.06193809871766158,-0.08248931576184856,0.5905162575930732,0.33605613026518444,0.6209579322675355,2.2811588937059706,-0.11936330150629972,0.6209579322675355,-0.30833420641619774,0.6209579322675355,2.190046332972387
2,627
Amide binding
34
92
2.173493
0.029743
O14773,P00374,O43731,Q9BYT8,Q15392,Q96AY3,P49748,P05165,P55786,Q8WTV0,Q9UIQ6,O00763,P21796,P42892,O00264,P40855,P62942,P07602,Q9NQX7,P41440,P52292,Q9UHV9,P61758,O00410,O60684,Q8TEX9,Q92973,P10321,P45880,Q15388,P11498,P21266,Q03519,P35610
Functions
GO Molecular function
msigdb_gomf
366,3,245,282,15,16,270,397,27,29,37,159,42,43,415,565,53,298,588,62,179,468,568,442,445,615,338,449,80,217,475,476,250,499
1796,415,442,159,366,2024,1797,245,445,2161,1301,3,2029,2227,397,298,1803,828,449,475,2409,476,42,1115,1117,2550,1072,1469,758,1930,499,1933,1582,565,1119,62,43,640,80,1156,1626,270,2538,2279,2539,179,1375,1809,27,1938,2335,568,53,1479,2109,2284,766,250,2511,2261,2179,647,1169,2337,217,15,615,29,2246,338,16,1599,810,1440,1225,618,1914,282,2383,1751,1504,1697,1182,588,1057,1791,1011,1704,468,37,1232,1020
-0.3470483341672869,0.7398788632872855,0.7105647803483593,1.1753918596827,0.79770532131495,-0.5857698248713581,-0.3470483341672869,0.9921697731964965,0.7105647803483593,-0.7510452441427796,0.026291598449343083,4.6645392746461,-0.5857698248713581,-0.8355204981110397,0.7689240696654053,0.9102846195726555,-0.3470483341672869,0.3689385488367404,0.7105647803483593,0.6809767597202617,-1.1856659423599307,0.6809767597202617,2.2811588937059706,0.16703565837514714,0.16703565837514714,-1.7964050577893755,0.20145406996397797,-0.08248931576184856,0.43378138483021883,-0.46502998509312093,0.6511095956652878,-0.46502998509312093,-0.15654406682019772,0.5905162575930732,0.16703565837514714,1.8999495008402818,2.245025739511523,0.5287400095236409,1.6690424559695667,0.13231016688164354,-0.1940315756095389,0.9651090844820442,-1.6990825136783276,-0.9212204426655155,-1.6990825136783276,1.124113729032047,-0.009661828907107638,-0.3470483341672869,2.9729491495441827,-0.46502998509312093,-1.008144828260293,0.5905162575930732,2.057947846284882,-0.08248931576184856,-0.6677949340288234,-0.9212204426655155,0.43378138483021883,0.9921697731964965,-1.555390872034156,-0.8782173997475797,-0.7510452441427796,0.5287400095236409,0.13231016688164354,-1.008144828260293,1.0456079279629058,3.5894737616308254,0.5597788975631283,2.870051204998666,-0.8355204981110397,0.8544949814735074,3.5292476415142087,-0.15654406682019772,0.4015136474761193,-0.045922145989749696,0.09727763420498443,0.5597788975631283,-0.42539625771276474,0.9651090844820442,-1.096293408964537,-0.26992668075220116,-0.08248931576184856,-0.23182579208405982,0.13231016688164354,0.5905162575930732,0.23556536257123337,-0.30833420641619774,0.2693694967580888,-0.23182579208405982,0.7105647803483593,2.653751179982698,0.09727763420498443,0.2693694967580888
2,627
Metabolism of steroids
15
38
2.172952
0.029784
P48449,Q16850,P37268,Q8NBQ5,Q9BWD1,O00763,Q14534,O00767,Q15392,Q86X55,Q9UBM7,P04062,Q9Y6B6,Q96SU4,P38435
Processes and pathways
Reactome Pathways
msigdb_reactome
32,33,2,288,241,159,457,473,15,149,83,111,260,490,321
159,473,1192,2253,2254,111,1304,2469,1115,1892,671,2,321,32,1626,1254,478,1541,1676,1815,938,836,457,800,1169,2318,15,1591,648,33,1546,149,288,490,1495,241,83,260
1.1753918596827,0.6809767597202617,0.09727763420498443,-0.8782173997475797,-0.8782173997475797,1.3725999294111904,0.026291598449343083,-1.3680819145279965,0.16703565837514714,-0.42539625771276474,0.49739460823615383,4.83909130728241,0.8825125816733365,2.779137843232317,-0.1940315756095389,0.06193809871766158,0.6809767597202617,-0.11936330150629972,-0.23182579208405982,-0.3470483341672869,0.3028664327170777,0.3689385488367404,0.7105647803483593,0.4015136474761193,0.13231016688164354,-0.9645295957870479,3.5894737616308254,-0.15654406682019772,0.5287400095236409,2.7637309800172836,-0.11936330150629972,1.2258544241347888,0.9378153921915153,0.6809767597202617,-0.08248931576184856,1.019001430589399,1.6690424559695667,0.9921697731964965
2,627
S phase
26
89
2.171943
0.02986
Q9Y619,P25788,Q96DE5,P24941,Q13309,Q9UJX4,O00231,P11802,P28070,Q9UJX6,Q9BRT9,Q9UL46,P49721,Q99436,P28072,P41440,P49841,P20618,Q7Z5K2,Q9UJX3,Q9NR33,P51530,P28074,P40938,P49720,P31751
Processes and pathways
Reactome Pathways
msigdb_reactome
131,374,137,10,133,413,391,267,26,158,437,176,50,327,58,62,69,193,211,84,93,234,99,349,351,112
391,1102,1957,1143,2095,752,1764,1614,2065,267,636,1529,1995,1575,193,10,1771,1306,714,374,424,757,1204,26,58,99,1074,1367,112,639,673,831,1370,2102,759,2579,1624,2171,1155,349,62,877,501,1475,351,50,1628,69,234,2138,2281,567,534,1633,1261,1675,681,937,988,1167,133,2238,837,2287,609,2316,802,1171,1131,211,950,137,327,2014,437,1138,620,93,2603,703,84,413,158,176,909,2369,1017,1236,131
0.7689240696654053,0.16703565837514714,-0.5049701777237011,0.13231016688164354,-0.6677949340288234,0.43378138483021883,-0.30833420641619774,-0.1940315756095389,-0.6266292131087098,0.9651090844820442,0.5287400095236409,-0.11936330150629972,-0.54521680207282,-0.15654406682019772,1.098160443332041,3.8637936648459883,-0.30833420641619774,0.026291598449343083,0.46574171914072615,0.79770532131495,0.7398788632872855,0.43378138483021883,0.09727763420498443,2.9873822734682727,1.9601213162571827,1.5128628531871786,0.20145406996397797,-0.009661828907107638,1.3725999294111904,0.5287400095236409,0.49739460823615383,0.3689385488367404,-0.009661828907107638,-0.6677949340288234,0.43378138483021883,-2.1466576685027245,-0.1940315756095389,-0.7510452441427796,0.13231016688164354,0.826227405842966,1.8999495008402818,0.33605613026518444,0.6511095956652878,-0.08248931576184856,0.826227405842966,2.1341018975806274,-0.1940315756095389,1.8386183095727955,1.019001430589399,-0.7092669551263342,-0.9212204426655155,0.5905162575930732,0.6209579322675355,-0.1940315756095389,0.06193809871766158,-0.23182579208405982,0.49739460823615383,0.3028664327170777,0.2693694967580888,0.13231016688164354,1.2755271358920077,-0.8355204981110397,0.3689385488367404,-0.9212204426655155,0.5597788975631283,-0.9645295957870479,0.4015136474761193,0.13231016688164354,0.16703565837514714,1.0719930390626526,0.3028664327170777,1.2755271358920077,0.8825125816733365,-0.54521680207282,0.7398788632872855,0.16703565837514714,0.5597788975631283,1.625197139203179,-2.672973127519375,0.49739460823615383,1.6690424559695667,0.7689240696654053,1.2007234515640317,1.1498563962326593,0.33605613026518444,-1.052066109456029,0.2693694967580888,0.09727763420498443,1.3000750023293999
2,627
Cns demyelination
6
12
2.151939
0.031402
Q9H9P8,Q14232,Q15067,P49770,P40855,P07602
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
465,129,286,271,565,298
298,565,599,271,1123,1321,129,286,1745,465,1395,1011
0.9102846195726555,0.5905162575930732,0.5597788975631283,0.9651090844820442,0.16703565837514714,0.026291598449343083,1.3000750023293999,0.9378153921915153,-0.26992668075220116,0.7105647803483593,-0.009661828907107638,0.2693694967580888
2,627
Metalloexopeptidase activity
9
20
2.146154
0.031861
Q9NQH7,Q9UIQ6,Q7Z2K6,P02786,O75976,P36551,P50579,P55786,P16870
Functions
GO Molecular function
msigdb_gomf
36,37,107,228,420,453,379,27,94
520,420,228,1202,1149,94,2490,453,379,27,107,655,1946,1283,854,36,959,1343,1791,37
0.6209579322675355,0.7398788632872855,1.019001430589399,0.09727763420498443,0.13231016688164354,1.580738688002121,-1.4611248851623608,0.7105647803483593,0.79770532131495,2.9729491495441827,1.4200457274830014,0.5287400095236409,-0.46502998509312093,0.06193809871766158,0.3689385488367404,2.6855622203641,0.3028664327170777,0.026291598449343083,-0.30833420641619774,2.653751179982698
2,627
Alcohol biosynthetic process
6
30
2.140279
0.032332
P48449,Q16850,P37268,P00374,Q15392,Q9UBM7
Processes and pathways
GO Biological process
msigdb_gobp
32,33,2,3,15,83
1291,633,2063,1615,3,923,111,2517,1886,1304,268,1619,2507,2,350,32,1125,478,1083,1815,2143,836,800,2318,15,648,33,2124,1918,83
0.026291598449343083,0.5287400095236409,-0.6266292131087098,-0.1940315756095389,4.6645392746461,0.3028664327170777,1.3725999294111904,-1.6029824257381295,-0.42539625771276474,0.026291598449343083,0.9651090844820442,-0.1940315756095389,-1.555390872034156,4.83909130728241,0.826227405842966,2.779137843232317,0.16703565837514714,0.6809767597202617,0.20145406996397797,-0.3470483341672869,-0.7092669551263342,0.3689385488367404,0.4015136474761193,-0.9645295957870479,3.5894737616308254,0.5287400095236409,2.7637309800172836,-0.6677949340288234,-0.42539625771276474,1.6690424559695667
2,627
Protein methyltransferase activity
16
22
2.127202
0.033403
Q99873,O60678,Q6UXN9,Q9H993,Q86X55,Q15291,Q7L592,Q9UBL3,Q15022,P61964,Q9H7B4,Q9BV86,Q52LJ0,O96028,Q14166,O60725
Functions
GO Molecular function
msigdb_gomf
362,519,612,587,149,301,218,554,402,505,30,25,574,63,401,31
1986,519,31,63,2542,1804,505,401,402,301,574,612,218,2495,149,806,362,25,30,587,554,624
-0.54521680207282,0.6209579322675355,2.779137843232317,1.879636801363511,-1.747590992462908,-0.3470483341672869,0.6511095956652878,0.7689240696654053,0.7689240696654053,0.9102846195726555,0.5905162575930732,0.5597788975631283,1.0456079279629058,-1.4611248851623608,1.2258544241347888,0.4015136474761193,0.826227405842966,3.1282415501804555,2.8400331419563334,0.5905162575930732,0.6209579322675355,0.5597788975631283
2,627
Steroid binding
11
18
2.111281
0.034748
O15118,O15173,Q14108,P21796,P30536,O00264,P04062,P45880,Q96SU4,P38435,P35610
Functions
GO Molecular function
msigdb_gomf
315,102,684,42,671,415,111,80,490,321,499
415,315,102,1615,2254,111,1883,711,42,1115,671,499,321,80,1421,684,490,1556
0.7398788632872855,0.8825125816733365,1.466793236485757,-0.1940315756095389,-0.8782173997475797,1.3725999294111904,-0.42539625771276474,0.46574171914072615,2.2811588937059706,0.16703565837514714,0.49739460823615383,0.6511095956652878,0.8825125816733365,1.6690424559695667,-0.045922145989749696,0.49739460823615383,0.6809767597202617,-0.11936330150629972
2,627
Ksrp khsrp binds and destabilizes mrna
7
10
2.10607
0.035198
Q13868,Q9Y2L1,P63104,Q96B26,Q5RKV6,Q9Y3B2,O95453
Processes and pathways
Reactome Pathways
msigdb_reactome
483,469,722,281,210,627,393
393,722,483,210,808,281,1446,1231,469,627
0.7689240696654053,0.46574171914072615,0.6809767597202617,1.0719930390626526,0.4015136474761193,0.9651090844820442,-0.045922145989749696,0.09727763420498443,0.7105647803483593,0.5597788975631283
2,627
ATP synthase
10
20
2.104216
0.03536
Q9Y5K8,P21281,P61421,Q93050,P24539,P21283,Q15904,O75964,Q9Y487,P38606
Functions
Panther Protein class
panther_protein_class
470,68,353,110,638,204,384,297,60,564
1461,297,1201,68,204,638,1929,1076,564,1583,1377,1257,353,384,1487,110,739,2090,60,470
-0.08248931576184856,0.9102846195726555,0.09727763420498443,1.8386183095727955,1.0719930390626526,0.5287400095236409,-0.46502998509312093,0.20145406996397797,0.5905162575930732,-0.15654406682019772,-0.009661828907107638,0.06193809871766158,0.826227405842966,0.79770532131495,-0.08248931576184856,1.3964114253159658,0.46574171914072615,-0.6266292131087098,1.9401901392777496,0.7105647803483593
2,627
Knee flexion contracture
11
25
2.103058
0.035461
P37268,P36543,Q9Y5P6,O00469,Q86XL3,P06753,P49902,Q96AY3,Q06210,Q969X5,P23786
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,283,70,443,406,524,378,16,207,580,21
443,706,592,2252,1615,1246,524,2305,1410,1891,21,1073,1368,283,2,2107,378,207,406,1177,580,16,1606,70,1455
0.7105647803483593,0.46574171914072615,0.5597788975631283,-0.8782173997475797,-0.1940315756095389,0.06193809871766158,0.6209579322675355,-0.9645295957870479,-0.045922145989749696,-0.42539625771276474,3.2499231036709753,0.20145406996397797,-0.009661828907107638,0.9378153921915153,4.83909130728241,-0.6677949340288234,0.79770532131495,1.0719930390626526,0.7689240696654053,0.13231016688164354,0.5905162575930732,3.5292476415142087,-0.15654406682019772,1.8386183095727955,-0.045922145989749696
2,627
Abnormal circulating fatty acid concentration
7
17
2.097327
0.035965
P11310,P35914,O43772,Q9P0S2,P49748,P40855,P23786
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
526,375,7,153,270,565,21
7,916,917,1519,1960,526,21,375,565,1119,270,1254,1777,2310,573,1697,153
4.226018188191668,0.3028664327170777,0.3028664327170777,-0.11936330150629972,-0.5049701777237011,0.6209579322675355,3.2499231036709753,0.79770532131495,0.5905162575930732,0.16703565837514714,0.9651090844820442,0.06193809871766158,-0.30833420641619774,-0.9645295957870479,0.5905162575930732,-0.23182579208405982,1.2258544241347888
2,627
Switching of origins to a post replicative state
25
56
2.097173
0.035978
P48556,Q9Y619,P25788,Q96DE5,P24941,Q13309,Q9UJX4,P33991,O00231,P28070,Q9UJX6,Q9UL46,Q9UJX2,P61289,P63208,P49721,P25789,Q99436,P28072,P60900,P20618,Q9H1A4,Q9UJX3,P28074,P49720
Processes and pathways
Reactome Pathways
msigdb_reactome
501,131,374,137,10,133,413,639,391,26,158,176,703,534,681,50,424,327,58,567,193,620,84,99,351
391,1102,1957,1143,2095,752,1614,1995,193,10,1771,1306,714,374,424,1204,26,58,99,1367,639,673,831,1624,877,501,351,50,1628,2138,2281,567,534,1633,1261,1675,681,937,1167,133,2238,837,2316,802,1171,137,327,2014,620,703,84,413,158,176,909,131
0.7689240696654053,0.16703565837514714,-0.5049701777237011,0.13231016688164354,-0.6677949340288234,0.43378138483021883,-0.1940315756095389,-0.54521680207282,1.098160443332041,3.8637936648459883,-0.30833420641619774,0.026291598449343083,0.46574171914072615,0.79770532131495,0.7398788632872855,0.09727763420498443,2.9873822734682727,1.9601213162571827,1.5128628531871786,-0.009661828907107638,0.5287400095236409,0.49739460823615383,0.3689385488367404,-0.1940315756095389,0.33605613026518444,0.6511095956652878,0.826227405842966,2.1341018975806274,-0.1940315756095389,-0.7092669551263342,-0.9212204426655155,0.5905162575930732,0.6209579322675355,-0.1940315756095389,0.06193809871766158,-0.23182579208405982,0.49739460823615383,0.3028664327170777,0.13231016688164354,1.2755271358920077,-0.8355204981110397,0.3689385488367404,-0.9645295957870479,0.4015136474761193,0.13231016688164354,1.2755271358920077,0.8825125816733365,-0.54521680207282,0.5597788975631283,0.49739460823615383,1.6690424559695667,0.7689240696654053,1.2007234515640317,1.1498563962326593,0.33605613026518444,1.3000750023293999
2,627
Perk regulates gene expression
6
12
2.064242
0.038995
Q13868,Q9Y2L1,Q96B26,Q5RKV6,O95453,P05198
Processes and pathways
Reactome Pathways
msigdb_reactome
483,469,281,210,393,561
393,561,1148,1113,483,210,808,281,1446,1231,469,627
0.7689240696654053,0.5905162575930732,0.13231016688164354,0.16703565837514714,0.6809767597202617,1.0719930390626526,0.4015136474761193,0.9651090844820442,-0.045922145989749696,0.09727763420498443,0.7105647803483593,0.5597788975631283
2,627
Abnormal circulating fatty acid anion concentration
6
13
2.055764
0.039805
P11310,P35914,O43772,Q9P0S2,P49748,P23786
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
526,375,7,153,270,21
7,1519,1960,526,21,375,1119,270,1777,2310,573,1697,153
4.226018188191668,-0.11936330150629972,-0.5049701777237011,0.6209579322675355,3.2499231036709753,0.79770532131495,0.16703565837514714,0.9651090844820442,-0.30833420641619774,-0.9645295957870479,0.5905162575930732,-0.23182579208405982,1.2258544241347888
2,627
Omega peptidase activity
8
19
2.053217
0.040052
O00303,P54578,Q01804,Q86UV5,Q96K76,Q9H8M7,O94966,Q93009
Functions
GO Molecular function
msigdb_gomf
471,479,142,385,126,222,332,461
471,1143,332,1028,1080,479,142,992,1644,730,385,1331,545,1597,461,848,126,222,1101
0.6809767597202617,0.13231016688164354,0.8544949814735074,0.23556536257123337,0.20145406996397797,0.6809767597202617,1.2507879522684213,0.2693694967580888,-0.1940315756095389,0.46574171914072615,0.79770532131495,0.026291598449343083,0.6209579322675355,-0.15654406682019772,0.7105647803483593,0.3689385488367404,1.3244345085536795,1.0456079279629058,0.20145406996397797
2,627
Iron uptake and transport
9
18
2.051986
0.040171
P21281,P36543,P61421,Q93050,Q9Y487,P02786,P21283,Q15904,P30519
Processes and pathways
Reactome Pathways
msigdb_reactome
68,283,353,110,60,228,204,384,90
919,228,870,68,204,2169,90,283,564,353,681,2238,384,1549,110,2090,60,470
0.3028664327170777,1.019001430589399,0.33605613026518444,1.8386183095727955,1.0719930390626526,-0.7510452441427796,1.625197139203179,0.9378153921915153,0.5905162575930732,0.826227405842966,0.49739460823615383,-0.8355204981110397,0.79770532131495,-0.11936330150629972,1.3964114253159658,-0.6266292131087098,1.9401901392777496,0.7105647803483593
2,627
V-type ATPase
6
8
2.048631
0.040498
Q9Y5K8,P21281,P61421,Q93050,P21283,Q9Y487
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
470,68,353,110,204,60
68,204,564,353,110,2090,60,470
1.8386183095727955,1.0719930390626526,0.5905162575930732,0.826227405842966,1.3964114253159658,-0.6266292131087098,1.9401901392777496,0.7105647803483593
2,627
Learning
9
13
2.046937
0.040664
A0AVT1,P18085,P42858,Q9NRG9,O00264,P50897,Q05086,Q9NPQ8,P38919
Processes and pathways
GO Biological process
msigdb_gobp
750,637,531,308,415,141,537,256,500
750,415,1767,637,500,531,141,793,537,1650,1495,256,308
0.43378138483021883,0.7398788632872855,-0.30833420641619774,0.5287400095236409,0.6511095956652878,0.6209579322675355,1.2507879522684213,0.4015136474761193,0.6209579322675355,-0.1940315756095389,-0.08248931576184856,0.9921697731964965,0.9102846195726555
2,627
Low set posteriorly rotated ears
17
60
2.042129
0.041139
Q15645,O60566,P37268,O43924,Q86V48,Q15813,Q15392,Q9UBM7,O43684,Q15022,P04062,Q8NCH0,Q9H3P2,Q06124,P16435,Q9BW83,O96028
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
432,97,2,35,136,357,15,83,226,402,111,219,187,399,268,328,63
226,35,1764,97,916,1925,63,111,869,562,1466,268,1365,1669,759,2,565,2260,980,719,1813,1814,1587,1380,1544,399,646,796,430,2287,402,1170,15,2320,885,432,357,946,949,611,1270,136,1551,219,1597,2123,328,551,2383,187,1394,1655,83,2450,1510,2369,1953,2405,1190,661
1.019001430589399,2.6855622203641,-0.30833420641619774,1.5356495831208603,0.3028664327170777,-0.46502998509312093,1.879636801363511,1.3725999294111904,0.33605613026518444,0.5905162575930732,-0.08248931576184856,0.9651090844820442,-0.009661828907107638,-0.23182579208405982,0.43378138483021883,4.83909130728241,0.5905162575930732,-0.8782173997475797,0.2693694967580888,0.46574171914072615,-0.3470483341672869,-0.3470483341672869,-0.15654406682019772,-0.009661828907107638,-0.11936330150629972,0.7689240696654053,0.5287400095236409,0.4015136474761193,0.7398788632872855,-0.9212204426655155,0.7689240696654053,0.13231016688164354,3.5894737616308254,-0.9645295957870479,0.33605613026518444,0.7398788632872855,0.826227405842966,0.3028664327170777,0.3028664327170777,0.5597788975631283,0.06193809871766158,1.2755271358920077,-0.11936330150629972,1.0456079279629058,-0.15654406682019772,-0.6677949340288234,0.8825125816733365,0.6209579322675355,-1.096293408964537,1.124113729032047,-0.009661828907107638,-0.1940315756095389,1.6690424559695667,-1.2762621894424164,-0.08248931576184856,-1.052066109456029,-0.46502998509312093,-1.1408266965924925,0.13231016688164354,0.5287400095236409
2,627
Lipoprotein metabolic process
7
15
2.040007
0.04135
Q8N2K0,Q5MNZ6,P50897,Q9H2M9,P04062,Q9NUJ1,Q9Y4P8
Processes and pathways
GO Biological process
msigdb_gobp
359,275,141,551,111,59,629
592,1570,867,111,1623,141,275,359,1179,955,1980,551,1007,59,629
0.5597788975631283,-0.15654406682019772,0.33605613026518444,1.3725999294111904,-0.1940315756095389,1.2507879522684213,0.9651090844820442,0.826227405842966,0.13231016688164354,0.3028664327170777,-0.5049701777237011,0.6209579322675355,0.2693694967580888,1.9401901392777496,0.5597788975631283
2,627
Apc c mediated degradation of cell cycle proteins
19
56
2.034558
0.041895
P25788,Q96DE5,P24941,Q13309,Q9UJX4,O00231,P28070,Q9UJX6,Q9UL46,P49721,Q99436,P28072,P20618,Q9UJX3,O60566,P06493,P28074,P49720,O43684
Processes and pathways
Reactome Pathways
msigdb_reactome
374,137,10,133,413,391,26,158,176,50,327,58,193,84,97,98,99,351,226
391,1102,1957,1143,2095,752,226,97,1614,98,2408,1995,193,10,1306,714,374,424,1204,26,58,99,1367,1624,877,501,351,50,2138,2412,2281,567,534,1633,1261,1675,681,937,2285,1167,133,2238,2316,802,1171,137,1911,327,2014,620,703,84,413,158,176,909
0.7689240696654053,0.16703565837514714,-0.5049701777237011,0.13231016688164354,-0.6677949340288234,0.43378138483021883,1.019001430589399,1.5356495831208603,-0.1940315756095389,1.5128628531871786,-1.1856659423599307,-0.54521680207282,1.098160443332041,3.8637936648459883,0.026291598449343083,0.46574171914072615,0.79770532131495,0.7398788632872855,0.09727763420498443,2.9873822734682727,1.9601213162571827,1.5128628531871786,-0.009661828907107638,-0.1940315756095389,0.33605613026518444,0.6511095956652878,0.826227405842966,2.1341018975806274,-0.7092669551263342,-1.1856659423599307,-0.9212204426655155,0.5905162575930732,0.6209579322675355,-0.1940315756095389,0.06193809871766158,-0.23182579208405982,0.49739460823615383,0.3028664327170777,-0.9212204426655155,0.13231016688164354,1.2755271358920077,-0.8355204981110397,-0.9645295957870479,0.4015136474761193,0.13231016688164354,1.2755271358920077,-0.42539625771276474,0.8825125816733365,-0.54521680207282,0.5597788975631283,0.49739460823615383,1.6690424559695667,0.7689240696654053,1.2007234515640317,1.1498563962326593,0.33605613026518444
2,627
Iron ion binding
7
16
2.031425
0.042212
Q16850,Q9BU89,O00469,Q9C0B1,Q32P28,P31350,Q9UMS0
Functions
GO Molecular function
msigdb_gomf
33,240,443,339,403,269,294
443,473,913,1528,1069,1469,269,1259,1853,33,403,2379,240,339,746,294
0.7105647803483593,0.6809767597202617,0.3028664327170777,-0.11936330150629972,0.20145406996397797,-0.08248931576184856,0.9651090844820442,0.06193809871766158,-0.38606902938103327,2.7637309800172836,0.7689240696654053,-1.096293408964537,1.019001430589399,0.8544949814735074,0.46574171914072615,0.9378153921915153
2,627
Organic acid transmembrane transport
7
24
2.031258
0.042229
Q9Y619,O43772,Q96NB2,P31751,P23786,Q9H2D1,P41440
Processes and pathways
GO Biological process
msigdb_gobp
131,7,152,112,21,87,62
7,2407,1300,2516,1767,1526,1248,1714,21,1532,112,477,62,205,1038,2141,2373,152,87,1698,466,907,495,131
4.226018188191668,-1.1856659423599307,0.026291598449343083,-1.6029824257381295,-0.30833420641619774,-0.11936330150629972,0.06193809871766158,-0.26992668075220116,3.2499231036709753,-0.11936330150629972,1.3725999294111904,0.6809767597202617,1.8999495008402818,1.0719930390626526,0.23556536257123337,-0.7092669551263342,-1.096293408964537,1.2258544241347888,1.6471953730994793,-0.23182579208405982,0.7105647803483593,0.33605613026518444,0.6809767597202617,1.3000750023293999
2,627
Elevated hepatic transaminase
28
83
2.018785
0.04351
Q9Y619,P35914,O43772,Q9P0S2,P49748,P23786,Q6NUQ1,Q02241,P28070,Q15067,P11310,P12235,Q8N511,O15305,P40855,P55263,Q16836,Q9Y3Z3,P04637,P09001,P50416,P16930,P20674,Q16658,P22695,Q15904,Q9Y6B6,Q4G176
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,375,7,153,270,21,147,536,26,286,526,527,578,416,565,55,573,201,560,448,205,450,451,485,597,384,260,508
2060,416,1105,7,592,917,1519,1404,922,560,1407,1067,448,1960,2136,526,527,1149,450,451,597,1070,21,26,1532,1074,2333,1471,375,1309,565,1119,1120,1537,270,205,1254,2307,1777,55,1937,1632,1938,1814,1041,1852,1999,1380,536,1165,796,1678,2143,800,286,384,485,573,1043,508,1133,147,1091,842,1490,578,2342,701,2215,1697,2555,1009,153,856,907,1061,910,2405,2268,1398,201,131,260
-0.6266292131087098,0.7398788632872855,0.16703565837514714,4.226018188191668,0.5597788975631283,0.3028664327170777,-0.11936330150629972,-0.045922145989749696,0.3028664327170777,0.5905162575930732,-0.045922145989749696,0.20145406996397797,0.7105647803483593,-0.5049701777237011,-0.7092669551263342,0.6209579322675355,0.6209579322675355,0.13231016688164354,0.7105647803483593,0.7105647803483593,0.5597788975631283,0.20145406996397797,3.2499231036709753,2.9873822734682727,-0.11936330150629972,0.20145406996397797,-1.008144828260293,-0.08248931576184856,0.79770532131495,0.026291598449343083,0.5905162575930732,0.16703565837514714,0.16703565837514714,-0.11936330150629972,0.9651090844820442,1.0719930390626526,0.06193809871766158,-0.9645295957870479,-0.30833420641619774,2.0386214496004125,-0.46502998509312093,-0.1940315756095389,-0.46502998509312093,-0.3470483341672869,0.23556536257123337,-0.38606902938103327,-0.54521680207282,-0.009661828907107638,0.6209579322675355,0.13231016688164354,0.4015136474761193,-0.23182579208405982,-0.7092669551263342,0.4015136474761193,0.9378153921915153,0.79770532131495,0.6809767597202617,0.5905162575930732,0.23556536257123337,0.6511095956652878,0.16703565837514714,1.2258544241347888,0.20145406996397797,0.3689385488367404,-0.08248931576184856,0.5905162575930732,-1.008144828260293,0.49739460823615383,-0.7931297690629023,-0.23182579208405982,-1.7964050577893755,0.2693694967580888,1.2258544241347888,0.3689385488367404,0.33605613026518444,0.23556536257123337,0.33605613026518444,-1.1408266965924925,-0.8782173997475797,-0.009661828907107638,1.098160443332041,1.3000750023293999,0.9921697731964965
2,627
Iron ion homeostasis
9
15
2.017139
0.043681
Q13492,P61421,Q9Y487,Q8N511,P02786,Q15904,Q9H3K6,P30519,P38606
Processes and pathways
GO Biological process
msigdb_gobp
647,353,60,578,228,384,389,90,564
1296,919,228,1842,870,2169,90,672,564,353,647,384,578,389,60
0.026291598449343083,0.3028664327170777,1.019001430589399,-0.38606902938103327,0.33605613026518444,-0.7510452441427796,1.625197139203179,0.49739460823615383,0.5905162575930732,0.826227405842966,0.5287400095236409,0.79770532131495,0.5905162575930732,0.79770532131495,1.9401901392777496
2,627
Carboxypeptidase activity
7
13
2.015194
0.043884
P42785,Q9H3G5,P10619,O75976,P36551,Q8IYS1,P16870
Functions
GO Molecular function
msigdb_gomf
9,40,229,420,453,182,94
420,229,1149,94,2490,453,9,2313,182,1946,1283,40,513
0.7398788632872855,1.019001430589399,0.13231016688164354,1.580738688002121,-1.4611248851623608,0.7105647803483593,3.9926369997259217,-0.9645295957870479,1.124113729032047,-0.46502998509312093,0.06193809871766158,2.5065447858132424,0.6511095956652878
2,627
Lipid droplet
7
26
2.012445
0.044173
P48449,Q99720,Q8NBQ5,Q8NF37,O43760,Q01105,Q8NBX0
Localization
GO Cellular component
msigdb_gocc
32,1,288,117,263,154,28
753,263,1800,1353,1522,923,2302,1525,32,1253,978,2429,1936,154,1211,648,692,288,28,117,489,2344,1,1394,1347,344
0.43378138483021883,0.9651090844820442,-0.3470483341672869,-0.009661828907107638,-0.11936330150629972,0.3028664327170777,-0.9645295957870479,-0.11936330150629972,2.779137843232317,0.06193809871766158,0.2693694967580888,-1.2308111164972735,-0.46502998509312093,1.2007234515640317,0.09727763420498443,0.5287400095236409,0.49739460823615383,0.9378153921915153,2.870051204998666,1.3486085433525787,0.6809767597202617,-1.008144828260293,5.731242825625463,-0.009661828907107638,0.026291598449343083,0.8544949814735074
2,627
Regulation of b cell activation
6
14
2.007145
0.044734
Q96FZ2,Q16512,Q96FV9,Q5RKV6,P02786,O96028
Processes and pathways
GO Biological process
msigdb_gobp
360,541,306,210,228,63
1838,63,559,228,871,1078,1213,541,210,1682,1000,306,360,1231
-0.38606902938103327,1.879636801363511,0.5905162575930732,1.019001430589399,0.33605613026518444,0.20145406996397797,0.09727763420498443,0.6209579322675355,1.0719930390626526,-0.23182579208405982,0.2693694967580888,0.9102846195726555,0.826227405842966,0.09727763420498443
2,627
Negative regulation of neuron projection development
11
15
1.997672
0.045752
P08670,P43034,Q9NR77,O14786,O14976,Q86X55,Q9P265,Q05086,Q9NQX7,Q96G23,Q8N0X7
Processes and pathways
GO Biological process
msigdb_gobp
371,715,38,313,224,149,780,537,588,326,692
313,224,371,2305,715,766,537,149,692,1005,326,1950,588,38,780
0.8825125816733365,1.019001430589399,0.79770532131495,-0.9645295957870479,0.46574171914072615,0.43378138483021883,0.6209579322675355,1.2258544241347888,0.49739460823615383,0.2693694967580888,0.8825125816733365,-0.46502998509312093,0.5905162575930732,2.5563715220078684,0.43378138483021883
2,627
Cellular hormone metabolic process
7
15
1.993591
0.046197
Q8NBQ5,Q6UWP2,Q92506,P42892,Q8TC12,O95470,Q9HB40
Processes and pathways
GO Biological process
msigdb_gobp
288,434,544,43,280,394,513
519,394,2469,671,43,1254,1546,434,1433,288,280,544,1226,513,1397
0.6209579322675355,0.7689240696654053,-1.3680819145279965,0.49739460823615383,2.245025739511523,0.06193809871766158,-0.11936330150629972,0.7398788632872855,-0.045922145989749696,0.9378153921915153,0.9651090844820442,0.6209579322675355,0.09727763420498443,0.6511095956652878,-0.009661828907107638
2,627
FAD/NAD(P)-binding domain superfamily [IPR036188]
7
16
1.98608
0.047024
Q9H9P8,Q9UHG3,Q14534,Q8NB78,P24386,O95831,O60341
Sequence
InterPro Superfamily
interpro_homologous_superfamily
465,67,457,150,452,89,214
214,89,523,1960,1892,452,1368,1934,1122,457,1431,839,150,735,465,67
1.0456079279629058,1.625197139203179,0.6209579322675355,-0.5049701777237011,-0.42539625771276474,0.7105647803483593,-0.009661828907107638,-0.46502998509312093,0.16703565837514714,0.7105647803483593,-0.045922145989749696,0.3689385488367404,1.2258544241347888,0.46574171914072615,0.7105647803483593,1.8591936372486821
2,627
Regulation of protein targeting
6
17
1.980559
0.047641
P49257,P27105,Q9Y371,P31751,Q9Y4C2,P55786
Processes and pathways
GO Biological process
msigdb_gobp
233,109,46,112,259,27
2476,1513,392,261,1246,109,112,233,27,1317,2394,779,1876,2266,1508,46,259
-1.4144505085562107,-0.11936330150629972,0.7689240696654053,0.9651090844820442,0.06193809871766158,1.3964114253159658,1.3725999294111904,1.019001430589399,2.9729491495441827,0.026291598449343083,-1.1408266965924925,0.43378138483021883,-0.38606902938103327,-0.8782173997475797,-0.08248931576184856,2.190046332972387,0.9921697731964965
2,627
mitochondria
6
10
1.975868
0.04817
Q9Y277,Q9NR31,P21796,Q8IWA4,P45880,Q15388
Localization
OpenCell Localization
opencell_localization
440,657,42,303,80,217
1301,42,80,725,217,303,1744,657,960,440
0.026291598449343083,2.2811588937059706,1.6690424559695667,0.46574171914072615,1.0456079279629058,0.9102846195726555,-0.26992668075220116,0.5287400095236409,0.3028664327170777,0.7398788632872855
2,627
Atf4 activates genes in response to endoplasmic reticulum stress
6
10
1.973147
0.048479
Q13868,Q9Y2L1,Q96B26,Q5RKV6,Q9Y3B2,O95453
Processes and pathways
Reactome Pathways
msigdb_reactome
483,469,281,210,627,393
393,1148,483,210,808,281,1446,1231,469,627
0.7689240696654053,0.13231016688164354,0.6809767597202617,1.0719930390626526,0.4015136474761193,0.9651090844820442,-0.045922145989749696,0.09727763420498443,0.7105647803483593,0.5597788975631283
2,627
Metatarsus adductus
6
11
1.972337
0.048571
Q13363,Q9H7D7,Q15392,Q9UBM7,Q9H2M9,O96028
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
430,410,15,83,551,63
1925,63,1669,1732,646,430,797,15,551,410,83
-0.46502998509312093,1.879636801363511,-0.23182579208405982,-0.26992668075220116,0.5287400095236409,0.7398788632872855,0.4015136474761193,3.5894737616308254,0.6209579322675355,0.7689240696654053,1.6690424559695667
2,627
Ambiguous genitalia
7
15
1.966566
0.049233
P53701,O60566,P21281,Q15392,Q9UBM7,O43684,P16435
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
323,97,68,15,83,226,268
751,226,97,268,68,1892,2205,323,2414,15,432,2472,738,83,1455
0.43378138483021883,1.019001430589399,1.5356495831208603,0.9651090844820442,1.8386183095727955,-0.42539625771276474,-0.7931297690629023,0.8825125816733365,-1.1856659423599307,3.5894737616308254,0.7398788632872855,-1.3680819145279965,0.46574171914072615,1.6690424559695667,-0.045922145989749696
2,627
Organic hydroxy compound biosynthetic process
7
42
1.966096
0.049288
P48449,Q16850,P37268,P00374,Q9Y4G8,Q15392,Q9UBM7
Processes and pathways
GO Biological process
msigdb_gobp
32,33,2,3,66,15,83
1291,1144,1192,2465,633,2063,1615,3,923,111,370,2517,1886,1304,268,1619,1115,1532,2507,2,350,32,1125,478,1083,1815,2143,836,457,800,2318,15,648,33,2049,490,2124,1226,1918,83,66,1455
0.026291598449343083,0.13231016688164354,0.09727763420498443,-1.3680819145279965,0.5287400095236409,-0.6266292131087098,-0.1940315756095389,4.6645392746461,0.3028664327170777,1.3725999294111904,0.79770532131495,-1.6029824257381295,-0.42539625771276474,0.026291598449343083,0.9651090844820442,-0.1940315756095389,0.16703565837514714,-0.11936330150629972,-1.555390872034156,4.83909130728241,0.826227405842966,2.779137843232317,0.16703565837514714,0.6809767597202617,0.20145406996397797,-0.3470483341672869,-0.7092669551263342,0.3689385488367404,0.7105647803483593,0.4015136474761193,-0.9645295957870479,3.5894737616308254,0.5287400095236409,2.7637309800172836,-0.5857698248713581,0.6809767597202617,-0.6677949340288234,0.09727763420498443,-0.42539625771276474,1.6690424559695667,1.879636801363511,-0.045922145989749696
2,627
Oxidoreductase
32
98
1.964511
0.049471
O43169,P00374,Q8N8N7,Q92506,Q8TC12,P49419,Q15392,P49748,O43674,P30837,P31350,Q16850,P00390,Q15067,Q6UWP2,P14406,P23921,Q8N4Q0,Q9H9P8,O75306,Q14534,O00469,Q9UBM7,P20674,P36551,O95831,O00483,Q9BY49,O95168,Q13423,P05091,P30048
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
368,3,8,544,280,13,15,270,262,22,269,33,523,286,434,169,423,183,465,316,457,443,83,451,453,89,472,104,227,480,370,122
443,472,368,751,262,1798,2025,1024,316,919,227,89,920,922,1199,3,523,1200,1842,2302,370,1109,2517,1960,2387,526,1886,756,1887,1303,169,1111,788,2469,1030,451,1410,2455,423,1307,2273,927,830,122,22,1368,269,928,975,453,1894,1808,1722,1934,1310,13,270,1584,1629,1374,602,1376,2284,1853,1588,480,457,800,286,15,1431,650,2145,33,839,1545,434,2290,2473,183,8,1864,735,280,2504,544,695,1226,104,1504,1697,465,2368,1344,83,1346,2600,783
0.7105647803483593,0.6809767597202617,0.79770532131495,0.43378138483021883,0.9651090844820442,-0.3470483341672869,-0.5857698248713581,0.23556536257123337,0.8825125816733365,0.3028664327170777,1.019001430589399,1.625197139203179,0.3028664327170777,0.3028664327170777,0.09727763420498443,4.6645392746461,0.6209579322675355,0.09727763420498443,-0.38606902938103327,-0.9645295957870479,0.79770532131495,0.16703565837514714,-1.6029824257381295,-0.5049701777237011,-1.1408266965924925,0.6209579322675355,-0.42539625771276474,0.43378138483021883,-0.42539625771276474,0.026291598449343083,1.1498563962326593,0.16703565837514714,0.4015136474761193,-1.3680819145279965,0.23556536257123337,0.7105647803483593,-0.045922145989749696,-1.3220191318378764,0.7398788632872855,0.026291598449343083,-0.9212204426655155,0.3028664327170777,0.3689385488367404,1.3244345085536795,3.209874236190353,-0.009661828907107638,0.9651090844820442,0.3028664327170777,0.2693694967580888,0.7105647803483593,-0.42539625771276474,-0.3470483341672869,-0.26992668075220116,-0.46502998509312093,0.026291598449343083,3.660283366374075,0.9651090844820442,-0.15654406682019772,-0.1940315756095389,-0.009661828907107638,0.5597788975631283,-0.009661828907107638,-0.9212204426655155,-0.38606902938103327,-0.15654406682019772,0.6809767597202617,0.7105647803483593,0.4015136474761193,0.9378153921915153,3.5894737616308254,-0.045922145989749696,0.5287400095236409,-0.7092669551263342,2.7637309800172836,0.3689385488367404,-0.11936330150629972,0.7398788632872855,-0.9212204426655155,-1.3680819145279965,1.124113729032047,4.1063697280400975,-0.38606902938103327,0.46574171914072615,0.9651090844820442,-1.5081050157800675,0.6209579322675355,0.49739460823615383,0.09727763420498443,1.443505472014357,-0.08248931576184856,-0.23182579208405982,0.7105647803483593,-1.052066109456029,0.026291598449343083,1.6690424559695667,0.026291598449343083,-2.618968128707429,0.43378138483021883
2,627
Negative regulation of calcium ion transmembrane transport
7
9
2.057512
0.039637
P78417,Q9UMX0,P21796,P30626,Q06787,P0DP25,P62258
Processes and pathways
GO Biological process
msigdb_gobp
510,270,170,462,485,366,370
366,170,528,462,370,1285,510,485,270
0.8423879397001103,1.279571951499236,0.5974733445112395,0.6903466836815487,0.8423879397001103,-0.022759045247130842,0.628572235823935,0.6595294678366483,1.0205359029519236
2,639
Negative regulation of calcium ion transport
7
9
2.057512
0.039637
P78417,Q9UMX0,P21796,P30626,Q06787,P0DP25,P62258
Processes and pathways
GO Biological process
msigdb_gobp
510,270,170,462,485,366,370
366,170,528,462,370,1285,510,485,270
0.8423879397001103,1.279571951499236,0.5974733445112395,0.6903466836815487,0.8423879397001103,-0.022759045247130842,0.628572235823935,0.6595294678366483,1.0205359029519236
2,639
calmodulin-related
8
12
2.004313
0.045037
P41208,O43852,Q02818,Q9BPX6,P0DP25,Q14257,P80303,Q99584
Functions
Panther Protein class
panther_protein_class
166,227,150,225,366,59,30,355
227,366,462,1224,166,30,150,59,992,355,225,1354
1.107938139235796,0.8423879397001103,0.6903466836815487,0.011390746091453784,1.3077805297783336,2.784329905308734,1.3917482655043385,2.056446863274501,0.17948837466703604,0.8723979107448686,1.1368332670103418,-0.057091219833927676
2,639
Intracellular calcium-sensing protein
8
13
1.992944
0.046268
P41208,O43852,Q02818,Q9BPX6,P0DP25,Q14257,P80303,Q99584
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
166,227,150,225,366,59,30,355
227,366,1224,166,421,30,150,59,992,1465,1138,355,225
1.107938139235796,0.8423879397001103,0.011390746091453784,1.3077805297783336,0.7515674878163875,2.784329905308734,1.3917482655043385,2.056446863274501,0.17948837466703604,-0.12631285148176882,0.0791529828848094,0.8723979107448686,1.1368332670103418
2,639
Calmodulin
8
13
1.992944
0.046268
P41208,O43852,Q02818,Q9BPX6,P0DP25,Q14257,P80303,Q99584
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
166,227,150,225,366,59,30,355
227,366,1224,166,421,30,150,59,992,1465,1138,355,225
1.107938139235796,0.8423879397001103,0.011390746091453784,1.3077805297783336,0.7515674878163875,2.784329905308734,1.3917482655043385,2.056446863274501,0.17948837466703604,-0.12631285148176882,0.0791529828848094,0.8723979107448686,1.1368332670103418
2,639
Protein import into mitochondrial matrix
6
9
2.277946
0.02273
Q3ZCQ8,Q15388,Q99595,O60830,O43615,O14925
Processes and pathways
GO Biological process
msigdb_gobp
196,229,6,7,149,215
215,149,7,804,298,229,196,6,1082
1.2651003863890502,1.6408116076633137,3.5729439775063003,0.27611959923976115,0.987323618563797,1.2088998635725174,1.3607405216360533,3.688553669933114,0.09437098307857111
2,640
mitochondria
6
10
2.228464
0.02585
Q15388,P21796,Q969Q5,Q8IWA4,P45880,Q9Y277
Localization
OpenCell Localization
opencell_localization
229,5,203,241,16,190
804,5,16,659,229,241,203,255,1209,190
0.27611959923976115,3.774483434248302,3.2720353200209913,0.4103414559555769,1.2088998635725174,1.165979950277032,1.3201648075100414,1.107693936415467,0.01002768041915923,1.4007140261492215
2,640
Steroid biosynthesis
6
9
2.220802
0.026364
Q14534,P48449,Q16850,Q15392,Q15738,P37268
Processes and pathways
KEGG Pathways
msigdb_kegg
169,74,45,78,154,59
392,168,59,74,169,78,154,45,479
0.7634769315060991,1.5044773534909244,2.560142064407259,2.38785837609098,1.5044773534909244,2.3244498287879454,1.5920513288211113,2.728192718141711,0.6446536277260322
2,640
Sphingolipid metabolism
7
8
2.184667
0.028913
O43681,P04062,O95470,Q06136,Q13510,P06280,P16278
Processes and pathways
KEGG Pathways
msigdb_kegg
126,265,143,17,370,313,376
434,126,143,265,313,376,17,370
0.6961743175446404,1.7932318696772285,1.688675538943332,1.0780846707376202,0.9564057068920355,0.7965490710106197,3.2720353200209913,0.8129435898906656
2,640
Intrinsic component of golgi membrane
6
8
2.167066
0.03023
O43505,L0R6Q1,Q9Y282,O95070,O15258,Q8TB61
Localization
GO Cellular component
msigdb_gocc
228,316,48,112,211,93
316,211,228,112,1791,93,372,48
0.9408187459219143,1.278971483114741,1.2088998635725174,1.8936776094288486,-0.3518878327905886,2.1532504607245895,0.8129435898906656,2.6892906751495107
2,640
Golgi cisterna membrane
7
11
2.120951
0.033926
Q15363,Q10472,Q10713,O00461,Q8NBN3,P51572,Q9H4A6
Localization
GO Cellular component
msigdb_gocc
258,106,111,79,148,212,121
79,731,212,106,111,258,148,1077,121,961,311
2.3060184568202247,0.33437526993861844,1.278971483114741,1.9370707557153821,1.9045962294636412,1.092928737627762,1.652860534618532,0.09437098307857111,1.82715694557132,0.17647916207103043,0.9719070688185447
2,640
Class i peroxisomal membrane protein import
6
8
2.110463
0.034818
P40855,Q9NR77,Q8NBU5,P51648,O75381,O43808
Processes and pathways
Reactome Pathways
msigdb_reactome
234,41,426,76,335,180
180,335,910,234,76,426,441,41
1.4401001876088586,0.8935362446658749,0.19666855779049566,1.1803611583843194,2.3789031102283555,0.7131471256572547,0.6961743175446404,2.8189021950656556
2,640
Cholesterol binding
7
11
2.077282
0.037776
P30536,P21796,O95772,P35610,P45880,Q14108,O15118
Functions
GO Molecular function
msigdb_gomf
33,5,290,168,16,23,122
122,1696,290,1285,5,322,33,168,16,469,23
1.815898681457796,-0.3043435893950832,1.0026561328666077,-0.05475899652005055,3.774483434248302,0.9408187459219143,2.9343652503508526,1.5044773534909244,3.2720353200209913,0.6446536277260322,3.180005880454657
2,640
Membrane lipid catabolic process
7
10
2.047722
0.040587
P04062,O95470,Q13510,P50897,P04066,P06280,P06865
Processes and pathways
GO Biological process
msigdb_gobp
265,143,370,82,281,313,188
143,265,281,313,188,1284,833,82,370,416
1.688675538943332,1.0780846707376202,1.0330721124821114,0.9564057068920355,1.4007140261492215,-0.05475899652005055,0.25644997306101663,2.249857673408694,0.8129435898906656,0.7300211919810663
2,640
Proteasome B-type subunit [IPR023333]
6
7
2.035105
0.04184
P28074,P20618,P28072,P28070,P49720,P49721
Sequence
InterPro Family
interpro_family
132,484,300,233,397,158
484,233,300,132,397,158,562
0.6272759688797264,1.1803611583843194,0.987323618563797,1.7703621682979278,0.7634769315060991,1.5673261817955972,0.5207940960509454
2,640
Proteasome core complex beta subunit complex
6
7
2.035105
0.04184
P28074,P20618,P28072,P28070,P49720,P49721
Localization
GO Cellular component
msigdb_gocc
132,484,300,233,397,158
484,233,300,132,397,158,562
0.6272759688797264,1.1803611583843194,0.987323618563797,1.7703621682979278,0.7634769315060991,1.5673261817955972,0.5207940960509454
2,640
Protein transmembrane transporter activity
6
11
2.022282
0.043147
Q07820,Q15388,Q99595,O60830,Q9NS69,O14925
Functions
GO Molecular function
msigdb_gomf
293,229,6,7,13,215
215,7,804,298,495,1099,293,229,6,13,1567
1.2651003863890502,3.5729439775063003,0.27611959923976115,0.987323618563797,0.609794556750599,0.07349865541604407,1.0026561328666077,1.2088998635725174,3.688553669933114,3.3716404019876354,-0.21131001115145295
2,640
Abnormal tissue metabolite concentration
6
11
2.019873
0.043397
O43681,P40855,O75381,P06280,P06865,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
126,234,335,313,188,129
126,335,313,188,360,1284,833,234,1123,129,1358
1.7932318696772285,0.8935362446658749,0.9564057068920355,1.4007140261492215,0.8292449430504332,-0.05475899652005055,0.25644997306101663,1.1803611583843194,0.052485075740458166,1.7932318696772285,-0.07665490103699212
2,640
Alcohol binding
8
13
2.0124
0.044178
P30536,P21796,O95772,P35610,P45880,O14735,Q14108,O15118
Functions
GO Molecular function
msigdb_gomf
33,5,290,168,16,272,23,122
272,122,1364,1696,290,1285,5,322,33,168,16,469,23
1.0631610253734936,1.815898681457796,-0.09870391765397812,-0.3043435893950832,1.0026561328666077,-0.05475899652005055,3.774483434248302,0.9408187459219143,2.9343652503508526,1.5044773534909244,3.2720353200209913,0.6446536277260322,3.180005880454657
2,640
Endoplasmic reticulum tubular network organization
6
9
2.008412
0.044599
Q6NUK4,O95197,P57088,Q9H6H4,Q8NHH9,Q9NQC3
Processes and pathways
GO Biological process
msigdb_gobp
127,36,257,171,440,114
36,257,1293,127,440,1353,171,499,114
2.898927947222865,1.092928737627762,-0.05475899652005055,1.7932318696772285,0.6961743175446404,-0.07665490103699212,1.5044773534909244,0.609794556750599,1.8936776094288486
2,640
Lysosomal lumen
16
31
2.949104
0.003187
P06865,Q9UMR5,P50897,P46976,P04066,P11117,P16278,P15586,P10619,Q99538,P06280,Q8NHP8,Q8IV08,Q14108,Q9BWS9,O14773
Localization
GO Cellular component
msigdb_gocc
128,64,34,321,96,100,137,381,72,313,147,25,27,28,364,159
159,1264,514,96,147,128,678,1174,2258,907,72,100,1808,381,137,578,398,321,34,722,518,731,28,27,2105,25,313,364,1791,480,64
1.3319174928236162,-0.07368673938911026,0.5212446036040174,1.879622475578631,1.4029341761024565,1.5886225408277,0.3291947939041686,-0.014495016828056225,-0.7327661943575732,0.1597365361720637,2.2211483087685453,1.8576861541850125,-0.37857891381214337,0.7337774627197764,1.5196047890008562,0.43965797637879195,0.7075984308018949,0.8374272713729306,3.315124122100504,0.3012707091060534,0.5212446036040174,0.3012707091060534,3.473152991049867,3.576579110864557,-0.5691719944139023,3.7289533607416123,0.8630780347854784,0.78581365326077,-0.3473913363783723,0.6017855487337226,2.4462872177254806
2,640
protein modifying enzyme
7
22
2.808092
0.004984
Q9UMR5,P50897,Q92791,O15460,O75718,O60725,P51812
Functions
Panther Protein class
panther_protein_class
64,34,66,170,139,45,176
821,1677,1263,170,1568,45,139,218,831,34,176,2102,1397,2381,1972,584,2204,66,1054,860,64,1616
0.2167382414483214,-0.31636373677520574,-0.07368673938911026,1.2841386816100955,-0.2547810983342171,2.7993759633154234,1.4731860089006816,1.1140827362508994,0.2167382414483214,3.315124122100504,1.2601167830969409,-0.5691719944139023,-0.13345627056560203,-0.8669609457812645,-0.4731205436056062,0.43965797637879195,-0.6667891587966922,2.385623388621299,0.07323647286201275,0.2167382414483214,2.4462872177254806,-0.2547810983342171
2,640
Negative regulation of mrna catabolic process
12
24
2.619295
0.008811
P16989,Q13151,Q99729,P35637,P07910,O60506,Q14103,Q9H074,Q92804,P67809,Q06787,Q14011
Processes and pathways
GO Biological process
msigdb_gobp
129,384,102,106,297,112,179,214,82,85,332,221
2559,112,1125,297,989,129,106,85,539,2317,332,1926,416,384,221,179,962,802,1149,82,102,214,1943,646
-1.4367046320616021,1.7245233122626071,0.014888098811455428,0.888626030424664,0.10220470852455128,1.5886225408277,1.8135950365776816,2.0311875124734295,0.49416676653861835,-0.7994837407245226,0.8116727965909163,-0.44144157913135773,0.681310760353538,0.7337774627197764,1.1140827362508994,1.2601167830969409,0.13103758702225834,0.24504373849492278,0.014888098811455428,2.073867908502337,1.8576861541850125,1.138652142304504,-0.44144157913135773,0.3846705364156224
2,640
Receptor
16
31
2.589339
0.009616
Q99720,P02786,O00264,Q9NS69,Q9Y2I1,P11717,Q14739,O15118,P11279,P24390,O15173,O43731,Q8WTV0,Q14108,Q9Y624,P35613
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
2,124,412,104,410,449,110,183,499,174,120,94,26,28,293,219
412,1067,183,120,94,124,1126,1683,1527,1863,1910,499,449,2484,1810,174,219,2389,1767,28,110,1448,26,2028,970,2,104,410,646,530,293
0.681310760353538,0.044131428334298,1.2360055619672616,1.65692314796553,1.9014866970979631,1.6342349180758022,0.014888098811455428,-0.31636373677520574,-0.22422245534187135,-0.40992835459390864,-0.44144157913135773,0.5482062652881979,0.6284053716418303,-1.1094088346960982,-0.37857891381214337,1.2601167830969409,1.1140827362508994,-0.9009906171012709,-0.3473913363783723,3.473152991049867,1.7469038463164606,-0.16356174978123925,3.6953724657069063,-0.5049672408828263,0.13103758702225834,5.583564036632601,1.835677190714375,0.7075984308018949,0.3846705364156224,0.5212446036040174,0.9140721885646405
2,640
Hydrolase activity acting on glycosyl bonds
6
21
2.587423
0.00967
P06865,P04066,Q9BTY2,O75503,P16278,Q9NUJ1
Functions
GO Molecular function
msigdb_gomf
128,96,98,35,137,95
617,425,35,514,96,147,128,1174,907,1686,137,578,945,947,831,722,2321,2145,766,98,95
0.3846705364156224,0.6549134221410868,3.261650795181371,0.5212446036040174,1.879622475578631,1.4029341761024565,1.5886225408277,-0.014495016828056225,0.1597365361720637,-0.31636373677520574,1.5196047890008562,0.43965797637879195,0.13103758702225834,0.13103758702225834,0.2167382414483214,0.3012707091060534,-0.7994837407245226,-0.6015342284507788,0.2732207890233398,1.879622475578631,1.9014866970979631
2,640
Rna stabilization
13
26
2.569898
0.010173
P16989,O95453,Q13151,Q13148,P35637,P07910,O60506,Q14103,Q9H074,Q92804,P67809,Q08J23,Q14011
Processes and pathways
GO Biological process
msigdb_gobp
129,283,384,416,106,297,112,179,214,82,85,306,221
112,2371,1125,283,297,989,129,106,85,539,2317,1926,306,416,384,221,179,962,802,1149,82,214,1667,463,1943,646
1.7245233122626071,-0.8669609457812645,0.014888098811455428,0.9140721885646405,0.888626030424664,0.10220470852455128,1.5886225408277,1.8135950365776816,2.0311875124734295,0.49416676653861835,-0.7994837407245226,-0.44144157913135773,0.8630780347854784,0.681310760353538,0.7337774627197764,1.1140827362508994,1.2601167830969409,0.13103758702225834,0.24504373849492278,0.014888098811455428,2.073867908502337,1.138652142304504,-0.28549426351975254,0.6284053716418303,-0.44144157913135773,0.3846705364156224
2,640
Micromelia
6
18
2.53955
0.0111
Q15392,P48735,Q9UBM7,Q14739,O75874,Q9UHX1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
4,5,39,110,20,54
2559,676,1523,2227,139,20,786,5,2135,2463,2018,110,4,807,39,54,1673,2406
-1.4367046320616021,0.3291947939041686,-0.22422245534187135,-0.6996862800086584,1.4731860089006816,3.8287611776161348,0.24504373849492278,4.958809583957812,-0.6015342284507788,-1.0391103140943438,-0.5049672408828263,1.7469038463164606,5.195749907486007,0.24504373849492278,3.1170308257343273,2.605465879915359,-0.28549426351975254,-0.9009906171012709
2,640
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
9
22
2.530641
0.011385
Q16850,P61457,P30519,O15460,Q9NWT6,Q8NB78,Q32P28,Q9BU89,P13674
Functions
GO Molecular function
msigdb_gomf
227,284,9,170,181,144,210,254,218
821,675,170,466,1626,1572,598,218,500,9,284,2102,1397,336,227,210,1452,2179,144,254,1356,181
0.2167382414483214,0.3291947939041686,1.2841386816100955,0.6017855487337226,-0.28549426351975254,-0.2547810983342171,0.41222468387452377,1.1140827362508994,0.5482062652881979,4.277093914090032,0.9140721885646405,-0.5691719944139023,-0.13345627056560203,0.8116727965909163,1.0894193056981731,1.138652142304504,-0.16356174978123925,-0.6340725528976131,1.4264355112747595,1.014856599416908,-0.10349847880370376,1.2601167830969409
2,640
Steroid binding
9
18
2.527352
0.011493
P21796,O00264,P30536,O15173,Q14108,P61916,P45880,P38435,O15118
Functions
GO Molecular function
msigdb_gomf
31,412,105,120,28,518,52,398,183
412,183,120,1372,1324,514,1807,1380,31,1178,105,1080,398,52,518,28,923,1843
0.681310760353538,1.2360055619672616,1.65692314796553,-0.13345627056560203,-0.10349847880370376,0.5212446036040174,-0.37857891381214337,-0.13345627056560203,3.3681944046475145,-0.014495016828056225,1.8135950365776816,0.044131428334298,0.7075984308018949,2.605465879915359,0.5212446036040174,3.473152991049867,0.1597365361720637,-0.37857891381214337
2,640
metalloprotease
6
25
2.446671
0.014418
P42892,Q9UIQ6,P55786,Q9BYT8,Q99797,P02786
Functions
Panther Protein class
panther_protein_class
74,17,56,154,158,124
1522,940,426,124,1866,2484,717,2131,1963,74,953,56,878,563,1097,1654,1783,1555,158,154,1515,1359,237,17,1315
-0.22422245534187135,0.13103758702225834,0.6549134221410868,1.6342349180758022,-0.40992835459390864,-1.1094088346960982,0.3012707091060534,-0.6015342284507788,-0.4731205436056062,2.2003045721183194,0.13103758702225834,2.5462078263759214,0.18830296043822092,0.4669716110301862,0.044131428334298,-0.28549426351975254,-0.3473913363783723,-0.22422245534187135,1.355675872407539,1.3793478634801224,-0.1938165802874622,-0.10349847880370376,1.0646610295240406,3.9108872628126026,-0.07368673938911026
2,640
Proton transporting two sector atpase complex
9
21
2.416267
0.015681
O75964,Q9Y487,Q8N511,P61421,Q15904,Q96IX5,O75947,P36543,Q93050
Localization
GO Cellular component
msigdb_gocc
130,107,202,201,404,375,427,431,59
427,130,596,429,755,679,1741,994,431,1282,1751,1390,1082,201,404,202,59,375,1466,107,589
0.6549134221410868,1.5656971489079918,0.41222468387452377,0.6549134221410868,0.2732207890233398,0.3291947939041686,-0.3473913363783723,0.10220470852455128,0.6549134221410868,-0.07368673938911026,-0.3473913363783723,-0.13345627056560203,0.044131428334298,1.1631283339474305,0.7075984308018949,1.1631283339474305,2.4864313476536455,0.7598488703542444,-0.16356174978123925,1.8135950365776816,0.43965797637879195
2,640
Lysosome
18
43
2.408999
0.015996
P06865,Q9UMR5,P50897,O75503,P04066,P09497,P11117,P16278,P10619,Q9Y487,P61421,Q9Y2T2,O15118,P06280,Q8NCC3,Q93050,Q14108,O14773
Processes and pathways
KEGG Pathways
msigdb_kegg
128,64,34,35,96,259,100,137,72,107,201,316,183,147,55,59,28,159
2481,2223,159,183,1264,2386,35,514,96,147,128,678,1174,259,907,72,100,499,449,381,137,578,34,685,722,201,518,2141,1444,731,28,404,55,2525,59,313,1302,1791,1466,814,64,316,107
-1.1094088346960982,-0.6996862800086584,1.3319174928236162,1.2360055619672616,-0.07368673938911026,-0.9009906171012709,3.261650795181371,0.5212446036040174,1.879622475578631,1.4029341761024565,1.5886225408277,0.3291947939041686,-0.014495016828056225,0.9898087461986675,0.1597365361720637,2.2211483087685453,1.8576861541850125,0.5482062652881979,0.6284053716418303,0.7337774627197764,1.5196047890008562,0.43965797637879195,3.315124122100504,0.3291947939041686,0.3012707091060534,1.1631283339474305,0.5212446036040174,-0.6015342284507788,-0.16356174978123925,0.3012707091060534,3.473152991049867,0.7075984308018949,2.5660176085751587,-1.2164694455838065,2.4864313476536455,0.8630780347854784,-0.07368673938911026,-0.3473913363783723,-0.16356174978123925,0.24504373849492278,2.4462872177254806,0.8630780347854784,1.8135950365776816
2,640
Organic acid transmembrane transport
6
24
2.400174
0.016387
P41440,Q9H2D1,Q9UBX3,O43772,P53985,P23786
Processes and pathways
GO Biological process
msigdb_gobp
68,37,302,11,178,184
11,2387,1371,2038,1126,1526,2125,1327,184,911,789,2088,68,1877,178,1647,1448,699,37,669,302,1313,1724,317
4.230361818944261,-0.9009906171012709,-0.13345627056560203,-0.5369837014554218,0.014888098811455428,-0.22422245534187135,-0.6015342284507788,-0.10349847880370376,1.2360055619672616,0.1597365361720637,0.24504373849492278,-0.5691719944139023,2.283296003247575,-0.40992835459390864,1.2601167830969409,-0.28549426351975254,-0.16356174978123925,0.3291947939041686,3.2077674049317846,0.3569943181163455,0.888626030424664,-0.07368673938911026,-0.31636373677520574,0.8630780347854784
2,640
Hyperlipidemia
8
23
2.376591
0.017473
P49257,P28070,Q969N2,P50402,Q92734,P06280,O95470,P23786
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
161,33,388,225,312,147,397,184
1729,1210,1266,426,397,1215,147,1684,1076,184,33,1743,789,161,225,1877,2193,1142,312,388,2241,1313,1024
-0.3473913363783723,-0.0440194452758567,-0.07368673938911026,0.6549134221410868,0.7075984308018949,-0.0440194452758567,1.4029341761024565,-0.31636373677520574,0.044131428334298,1.2360055619672616,3.315124122100504,-0.3473913363783723,0.24504373849492278,1.3319174928236162,1.0894193056981731,-0.40992835459390864,-0.6667891587966922,0.014888098811455428,0.8630780347854784,0.7337774627197764,-0.6996862800086584,-0.07368673938911026,0.10220470852455128
2,640
Exopeptidase activity
11
32
2.352742
0.018636
P42785,P10619,Q9NZ08,Q9H3G5,O75976,Q9UIQ6,Q969V3,P55786,Q9HB40,P02786,O14773
Functions
GO Molecular function
msigdb_gomf
6,72,237,109,295,17,280,56,29,124,159
159,426,295,124,623,72,1866,1028,2131,1690,305,6,538,685,56,2319,2322,1097,1600,1654,460,280,1783,2298,109,2069,29,1515,2470,1359,237,17
1.3319174928236162,0.6549134221410868,0.888626030424664,1.6342349180758022,0.3846705364156224,2.2211483087685453,-0.40992835459390864,0.07323647286201275,-0.6015342284507788,-0.31636373677520574,0.8630780347854784,4.5663340066944285,0.49416676653861835,0.3291947939041686,2.5462078263759214,-0.7994837407245226,-0.7994837407245226,0.044131428334298,-0.2547810983342171,-0.28549426351975254,0.6284053716418303,0.9394174264118705,-0.3473913363783723,-0.7660312248149689,1.7692089294006392,-0.5369837014554218,3.473152991049867,-0.1938165802874622,-1.0391103140943438,-0.10349847880370376,1.0646610295240406,3.9108872628126026
2,640
Mitochondrial respiratory chain complex assembly
13
31
2.351716
0.018687
O95168,Q9BSK2,Q6DKK2,O95831,O43676,O43674,Q9P0J0,Q9P0S2,Q69YU5,Q7L592,O96000,Q9Y2R0,Q9H061
Processes and pathways
GO Biological process
msigdb_gobp
195,133,103,43,171,142,217,111,51,311,303,90,289
142,171,1370,986,748,941,195,1569,43,303,2486,792,504,1449,2354,51,103,311,848,735,133,1607,289,1417,2515,217,111,2455,90,513,346
1.4498525610927513,1.2841386816100955,-0.13345627056560203,0.10220470852455128,0.2732207890233398,0.13103758702225834,1.1875121104347612,-0.2547810983342171,2.9506722512959525,0.8630780347854784,-1.1094088346960982,0.24504373849492278,0.5482062652881979,-0.16356174978123925,-0.8331261590690011,2.6251051132427428,1.835677190714375,0.8630780347854784,0.2167382414483214,0.3012707091060534,1.5656971489079918,-0.2547810983342171,0.9140721885646405,-0.13345627056560203,-1.1805635442591855,1.138652142304504,1.7469038463164606,-1.004274885567509,1.9450009779949093,0.5482062652881979,0.8116727965909163
2,640
Negative regulation of mrna metabolic process
18
41
2.27783
0.022737
P16989,Q13151,Q99729,P61978,Q13148,P35637,P07910,O60506,Q14103,Q92804,Q9H074,O75494,P38159,P67809,P22626,Q06787,Q14011,Q13242
Processes and pathways
GO Biological process
msigdb_gobp
129,384,102,165,416,106,297,112,179,82,214,328,113,85,118,332,221,220
2559,777,1120,112,939,328,1125,297,989,129,599,118,991,1077,106,113,165,85,539,2317,332,435,629,1926,838,416,384,220,1289,221,179,962,843,1453,802,1149,82,102,214,1943,646
-1.4367046320616021,0.24504373849492278,0.014888098811455428,1.7245233122626071,0.13103758702225834,0.8116727965909163,0.014888098811455428,0.888626030424664,0.10220470852455128,1.5886225408277,0.41222468387452377,1.6795335557999362,0.10220470852455128,0.044131428334298,1.8135950365776816,1.7245233122626071,1.3080720054464956,2.0311875124734295,0.49416676653861835,-0.7994837407245226,0.8116727965909163,0.6549134221410868,0.3846705364156224,-0.44144157913135773,0.2167382414483214,0.681310760353538,0.7337774627197764,1.1140827362508994,-0.07368673938911026,1.1140827362508994,1.2601167830969409,0.13103758702225834,0.2167382414483214,-0.16356174978123925,0.24504373849492278,0.014888098811455428,2.073867908502337,1.8576861541850125,1.138652142304504,-0.44144157913135773,0.3846705364156224
2,640
reductase
6
28
2.276613
0.022809
P00374,Q06136,Q15392,O95881,Q9UBM7,Q9BY49
Functions
Panther Protein class
panther_protein_class
1,3,4,71,39,93
2168,71,1,1908,1270,622,1217,944,2485,2597,1633,1383,680,1746,949,3,110,4,689,2438,2635,1894,93,442,2033,1792,39,981
-0.6340725528976131,2.241927828624333,5.674293168464698,-0.44144157913135773,-0.07368673938911026,0.3846705364156224,-0.0440194452758567,0.13103758702225834,-1.1094088346960982,-1.823654433194548,-0.28549426351975254,-0.13345627056560203,0.3291947939041686,-0.3473913363783723,0.13103758702225834,5.478539401482258,1.7469038463164606,5.195749907486007,0.3291947939041686,-0.9696449385388588,-5.173034750253889,-0.40992835459390864,1.9232793546600666,0.6549134221410868,-0.5049672408828263,-0.3473913363783723,3.1170308257343273,0.13103758702225834
2,640
Abnormal neuron morphology
8
26
2.274003
0.022966
Q99720,P09651,P50995,P35637,Q92804,Q92734,P22626,Q16637
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,413,352,106,82,312,118,418
1729,1372,1629,536,413,1178,2343,118,1812,106,1183,352,1226,2094,416,731,1772,418,1242,312,82,2,971,2158,1418,864
-0.3473913363783723,-0.13345627056560203,-0.28549426351975254,0.49416676653861835,0.681310760353538,-0.014495016828056225,-0.8331261590690011,1.6795335557999362,-0.37857891381214337,1.8135950365776816,-0.014495016828056225,0.78581365326077,-0.0440194452758567,-0.5691719944139023,0.681310760353538,0.3012707091060534,-0.3473913363783723,0.681310760353538,-0.0440194452758567,0.8630780347854784,2.073867908502337,5.583564036632601,0.13103758702225834,-0.6015342284507788,-0.13345627056560203,0.2167382414483214
2,640
Cellular response to molecule of bacterial origin
7
23
2.258109
0.023939
O43823,Q86UE4,P30536,P14174,Q8IXJ6,Q8WTV0,Q9NUQ9
Processes and pathways
GO Biological process
msigdb_gobp
318,299,105,14,150,26,326
318,827,350,2259,1072,14,1480,2310,1581,105,1031,1707,2393,1833,299,150,1976,26,1150,2109,326,644,1518
0.8374272713729306,0.2167382414483214,0.78581365326077,-0.7327661943575732,0.044131428334298,3.927200610431849,-0.1938165802874622,-0.7994837407245226,-0.2547810983342171,1.8135950365776816,0.07323647286201275,-0.31636373677520574,-0.9009906171012709,-0.37857891381214337,0.888626030424664,1.4029341761024565,-0.4731205436056062,3.6953724657069063,0.014888098811455428,-0.5691719944139023,0.8374272713729306,0.3846705364156224,-0.1938165802874622
2,640
SLC superfamily of solute carriers
10
32
2.253077
0.024254
P41440,Q9H2D1,Q9BSK2,Q9UBX3,Q8IXU6,Q8TB61,O43772,P53985,Q99808,Q70HW3
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
68,37,133,302,40,300,11,178,81,24
11,1470,1371,1804,1736,2125,1327,2308,1865,68,178,2433,2414,1647,1448,1549,2539,24,40,300,699,81,133,37,669,2514,1791,302,1313,1724,317,1316
4.230361818944261,-0.1938165802874622,-0.13345627056560203,-0.37857891381214337,-0.3473913363783723,-0.6015342284507788,-0.10349847880370376,-0.7994837407245226,-0.40992835459390864,2.283296003247575,1.2601167830969409,-0.9696449385388588,-0.9352177409809121,-0.28549426351975254,-0.16356174978123925,-0.22422245534187135,-1.2889538712883826,3.7289533607416123,3.080403919701365,0.888626030424664,0.3291947939041686,2.0951066247996866,1.5656971489079918,3.2077674049317846,0.3569943181163455,-1.1805635442591855,-0.3473913363783723,0.888626030424664,-0.07368673938911026,-0.31636373677520574,0.8630780347854784,-0.07368673938911026
2,640
Muscle organ development
8
25
2.246755
0.024656
P16989,P51114,P41440,P50402,P62942,Q8IXJ6,Q9BYT8,P30626
Processes and pathways
GO Biological process
msigdb_gobp
129,67,68,225,49,150,154,191
2227,619,712,2554,129,870,191,2266,68,2053,225,67,1391,557,1393,49,270,1762,1828,150,510,154,1464,1852,1166
-0.6996862800086584,0.3846705364156224,0.3012707091060534,-1.3994107630493304,1.5886225408277,0.18830296043822092,1.211804260384147,-0.7327661943575732,2.283296003247575,-0.5369837014554218,1.0894193056981731,2.32441261854729,-0.13345627056560203,0.4669716110301862,-0.13345627056560203,2.683687590296434,0.9646626483533066,-0.3473913363783723,-0.37857891381214337,1.4029341761024565,0.5482062652881979,1.3793478634801224,-0.16356174978123925,-0.37857891381214337,0.014888098811455428
2,640
oxidoreductase
10
38
2.246065
0.0247
Q8N0U8,Q15067,O95168,O95831,O43676,O43674,Q8N4Q0,Q6DKJ4,O96000,O43169
Functions
Panther Protein class
panther_protein_class
325,226,195,43,171,142,15,188,303,91
822,779,91,1122,142,171,748,195,1172,43,303,1374,2122,1071,1739,500,1530,1330,1332,1032,625,1874,226,842,1449,2354,1043,188,1238,848,325,15,1049,1461,1981,1251,1115,346
0.2167382414483214,0.24504373849492278,1.9232793546600666,0.014888098811455428,1.4498525610927513,1.2841386816100955,0.2732207890233398,1.1875121104347612,-0.014495016828056225,2.9506722512959525,0.8630780347854784,-0.13345627056560203,-0.6015342284507788,0.044131428334298,-0.3473913363783723,0.5482062652881979,-0.22422245534187135,-0.10349847880370376,-0.10349847880370376,0.07323647286201275,0.3846705364156224,-0.40992835459390864,1.0894193056981731,0.2167382414483214,-0.16356174978123925,-0.8331261590690011,0.07323647286201275,1.2360055619672616,-0.0440194452758567,0.2167382414483214,0.8374272713729306,3.927200610431849,0.07323647286201275,-0.16356174978123925,-0.4731205436056062,-0.0440194452758567,0.044131428334298,0.8116727965909163
2,640
Negative regulation of rna catabolic process
15
31
2.236435
0.025323
P16989,O95453,Q13151,Q13148,Q99729,P35637,P07910,O60506,Q14103,Q9H074,Q92804,P67809,Q06787,Q08J23,Q14011
Processes and pathways
GO Biological process
msigdb_gobp
129,283,384,416,102,106,297,112,179,214,82,85,332,306,221
2559,112,2371,1125,283,297,989,129,106,1696,85,539,2317,332,1926,306,416,384,221,179,962,802,1149,82,102,973,214,1667,463,1943,646
-1.4367046320616021,1.7245233122626071,-0.8669609457812645,0.014888098811455428,0.9140721885646405,0.888626030424664,0.10220470852455128,1.5886225408277,1.8135950365776816,-0.31636373677520574,2.0311875124734295,0.49416676653861835,-0.7994837407245226,0.8116727965909163,-0.44144157913135773,0.8630780347854784,0.681310760353538,0.7337774627197764,1.1140827362508994,1.2601167830969409,0.13103758702225834,0.24504373849492278,0.014888098811455428,2.073867908502337,1.8576861541850125,0.13103758702225834,1.138652142304504,-0.28549426351975254,0.6284053716418303,-0.44144157913135773,0.3846705364156224
2,640
Disproportionate short stature
7
17
2.218527
0.026519
Q15392,Q9UBM7,P16278,O75718,Q14739,Q9UHX1,Q6DKJ4
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
4,39,137,139,110,54,188
411,1730,2227,139,786,137,1869,2313,1533,110,2599,4,210,188,807,39,54
0.681310760353538,-0.3473913363783723,-0.6996862800086584,1.4731860089006816,0.24504373849492278,1.5196047890008562,-0.40992835459390864,-0.7994837407245226,-0.22422245534187135,1.7469038463164606,-1.823654433194548,5.195749907486007,1.138652142304504,1.2360055619672616,0.24504373849492278,3.1170308257343273,2.605465879915359
2,640
Motor neuron atrophy
8
21
2.216547
0.026654
Q99720,P09651,P50995,P35637,Q92804,Q92734,P22626,Q16637
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,413,352,106,82,312,118,418
1629,536,413,2343,118,1812,106,1183,352,2094,416,731,1772,418,312,82,2,971,2158,1418,864
-0.28549426351975254,0.49416676653861835,0.681310760353538,-0.8331261590690011,1.6795335557999362,-0.37857891381214337,1.8135950365776816,-0.014495016828056225,0.78581365326077,-0.5691719944139023,0.681310760353538,0.3012707091060534,-0.3473913363783723,0.681310760353538,0.8630780347854784,2.073867908502337,5.583564036632601,0.13103758702225834,-0.6015342284507788,-0.13345627056560203,0.2167382414483214
2,640
Mitochondrial transmembrane transport
10
43
2.181621
0.029138
P21796,O75964,Q9H2D1,Q9BSK2,O43772,O95831,Q99595,Q15388,O60830,P23786
Processes and pathways
GO Biological process
msigdb_gobp
31,130,37,133,11,43,88,222,61,184
447,1170,11,61,1426,940,1371,427,130,1524,1804,43,782,1736,596,1476,2308,1865,31,184,679,1741,994,1751,1877,1390,1082,2414,222,844,232,1659,699,88,1055,133,37,669,495,1313,1112,1315,317
0.6284053716418303,-0.014495016828056225,4.230361818944261,2.46638885828074,-0.16356174978123925,0.13103758702225834,-0.13345627056560203,0.6549134221410868,1.5656971489079918,-0.22422245534187135,-0.37857891381214337,2.9506722512959525,0.24504373849492278,-0.3473913363783723,0.41222468387452377,-0.1938165802874622,-0.7994837407245226,-0.40992835459390864,3.3681944046475145,1.2360055619672616,0.3291947939041686,-0.3473913363783723,0.10220470852455128,-0.3473913363783723,-0.40992835459390864,-0.13345627056560203,0.044131428334298,-0.9352177409809121,1.1140827362508994,0.2167382414483214,1.0646610295240406,-0.28549426351975254,0.3291947939041686,2.0097448491460064,0.07323647286201275,1.5656971489079918,3.2077674049317846,0.3569943181163455,0.5750528773771129,-0.07368673938911026,0.044131428334298,-0.07368673938911026,0.8630780347854784
2,640
Neurotransmitter transport
11
23
2.142688
0.032138
P50897,P41440,P56545,O95721,Q99808,Q9P253,O14936,P0DP25,Q06787,P35080,O00161
Processes and pathways
GO Biological process
msigdb_gobp
34,68,580,577,81,614,549,206,332,430,590
590,1261,2224,549,619,577,1126,206,1277,2044,430,68,1388,34,1188,580,332,1191,879,1403,2526,81,614
0.41222468387452377,-0.07368673938911026,-0.6996862800086584,0.4669716110301862,0.3846705364156224,0.43965797637879195,0.014888098811455428,1.138652142304504,-0.07368673938911026,-0.5369837014554218,0.6549134221410868,2.283296003247575,-0.13345627056560203,3.315124122100504,-0.014495016828056225,0.43965797637879195,0.8116727965909163,-0.014495016828056225,0.18830296043822092,-0.13345627056560203,-1.2164694455838065,2.0951066247996866,0.41222468387452377
2,640
Platyspondyly
7
26
2.140259
0.032334
P04066,P48735,P16278,O95831,Q14739,O75874,Q96AY3
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
96,5,137,43,110,20,157
821,2408,2227,20,43,1806,96,137,1958,1869,2377,1746,5,2135,2013,1492,2102,110,2599,210,455,1549,768,2329,157,1796
0.2167382414483214,-0.9352177409809121,-0.6996862800086584,3.8287611776161348,2.9506722512959525,-0.37857891381214337,1.879622475578631,1.5196047890008562,-0.4731205436056062,-0.40992835459390864,-0.8669609457812645,-0.3473913363783723,4.958809583957812,-0.6015342284507788,-0.5049672408828263,-0.1938165802874622,-0.5691719944139023,1.7469038463164606,-1.823654433194548,1.138652142304504,0.6284053716418303,-0.22422245534187135,0.2732207890233398,-0.7994837407245226,1.355675872407539,-0.3473913363783723
2,640
ATP synthase
9
20
2.098287
0.03588
Q9Y5K8,O75964,Q9Y487,P61421,Q15904,Q96IX5,O75947,P21281,Q93050
Functions
Panther Protein class
panther_protein_class
589,130,107,201,404,375,427,429,59
427,130,596,429,755,679,1741,994,1282,1751,1390,1082,201,404,1404,59,375,1466,107,589
0.6549134221410868,1.5656971489079918,0.41222468387452377,0.6549134221410868,0.2732207890233398,0.3291947939041686,-0.3473913363783723,0.10220470852455128,-0.07368673938911026,-0.3473913363783723,-0.13345627056560203,0.044131428334298,1.1631283339474305,0.7075984308018949,-0.13345627056560203,2.4864313476536455,0.7598488703542444,-0.16356174978123925,1.8135950365776816,0.43965797637879195
2,640
Peroxisome
6
29
2.094683
0.036199
Q15067,Q9BQG2,P48735,Q9NR77,O75874,Q9BY49
Processes and pathways
KEGG Pathways
msigdb_kegg
226,164,5,19,20,93
411,710,1730,1470,1997,653,2253,20,1906,2122,1178,911,1332,2088,1919,912,5,1333,1228,401,226,2603,1148,245,164,93,19,1022,2161
0.681310760353538,0.3012707091060534,-0.3473913363783723,-0.1938165802874622,-0.5049672408828263,0.3569943181163455,-0.7327661943575732,3.8287611776161348,-0.44144157913135773,-0.6015342284507788,-0.014495016828056225,0.1597365361720637,-0.10349847880370376,-0.5691719944139023,-0.44144157913135773,0.1597365361720637,4.958809583957812,-0.10349847880370376,-0.0440194452758567,0.7075984308018949,1.0894193056981731,-1.863839644810072,0.014888098811455428,1.0398070753671265,1.3319174928236162,1.9232793546600666,3.845261620281099,0.10220470852455128,-0.6015342284507788
2,640
Sensory neuropathy
6
22
2.08559
0.037016
Q15067,O95831,P34897,P22626,Q8IV08,Q03001
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
226,43,175,118,27,260
1367,1732,1472,1372,43,1374,413,1868,118,2541,175,1283,1921,1186,2094,1821,260,226,27,1659,312,643
-0.13345627056560203,-0.3473913363783723,-0.1938165802874622,-0.13345627056560203,2.9506722512959525,-0.13345627056560203,0.681310760353538,-0.40992835459390864,1.6795335557999362,-1.3255388156594834,1.2601167830969409,-0.07368673938911026,-0.44144157913135773,-0.014495016828056225,-0.5691719944139023,-0.37857891381214337,0.9898087461986675,1.0894193056981731,3.576579110864557,-0.28549426351975254,0.8630780347854784,0.3846705364156224
2,640