term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
2 3 toe syndactyly
7
21
2.049922
0.040372
Q9UBM7,P37268,O43924,P51812,P34897,Q9UHX1,P11233
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
39,7,10,176,175,54,152
1994,1729,10,1997,152,2445,175,7,1533,1754,176,2433,211,2511,2358,1303,2621,1156,39,54,423
-0.5049672408828263,-0.3473913363783723,4.245972472208045,-0.5049672408828263,1.3793478634801224,-1.004274885567509,1.2601167830969409,4.50638025156063,-0.22422245534187135,-0.3473913363783723,1.2601167830969409,-0.9696449385388588,1.138652142304504,-1.1805635442591855,-0.8331261590690011,-0.07368673938911026,-2.9725098225080737,0.014888098811455428,3.1170308257343273,2.605465879915359,0.681310760353538
2,640
Negative regulation of cell projection organization
6
24
2.048939
0.040468
Q8N0X7,P08670,Q9NQX7,Q9NR77,O14976,Q9Y4G8
Processes and pathways
GO Biological process
msigdb_gobp
339,350,407,19,327,32
1067,327,905,350,1958,1179,430,1483,1137,1185,2010,687,795,796,1762,584,339,1661,1350,1848,407,19,1944,32
0.044131428334298,0.8116727965909163,0.1597365361720637,0.78581365326077,-0.4731205436056062,-0.014495016828056225,0.6549134221410868,-0.1938165802874622,0.014888098811455428,-0.014495016828056225,-0.5049672408828263,0.3291947939041686,0.24504373849492278,0.24504373849492278,-0.3473913363783723,0.43965797637879195,0.8116727965909163,-0.28549426351975254,-0.10349847880370376,-0.37857891381214337,0.7075984308018949,3.845261620281099,-0.44144157913135773,3.3681944046475145
2,640
Transferrin endocytosis and recycling
6
11
2.042423
0.04111
Q9Y487,P61421,Q15904,P36543,Q93050,P02786
Processes and pathways
Reactome Pathways
msigdb_reactome
107,201,404,431,59,124
124,429,755,431,1282,201,404,59,1466,107,589
1.6342349180758022,0.6549134221410868,0.2732207890233398,0.6549134221410868,-0.07368673938911026,1.1631283339474305,0.7075984308018949,2.4864313476536455,-0.16356174978123925,1.8135950365776816,0.43965797637879195
2,640
Hydrogen ion transport
9
19
2.041344
0.041217
Q9Y5K8,O75964,Q9Y487,P61421,Q15904,O75947,P36543,P21281,Q93050
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
589,130,107,201,404,427,431,429,59
427,130,596,429,755,679,1741,994,431,1282,1751,1390,1082,201,404,59,1466,107,589
0.6549134221410868,1.5656971489079918,0.41222468387452377,0.6549134221410868,0.2732207890233398,0.3291947939041686,-0.3473913363783723,0.10220470852455128,0.6549134221410868,-0.07368673938911026,-0.3473913363783723,-0.13345627056560203,0.044131428334298,1.1631283339474305,0.7075984308018949,2.4864313476536455,-0.16356174978123925,1.8135950365776816,0.43965797637879195
2,640
Amyotrophic lateral sclerosis
6
15
2.039119
0.041438
Q99720,P09651,P50995,P35637,Q92804,P22626
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,413,352,106,82,118
1629,536,413,118,1812,106,1183,352,2094,416,1772,82,2,1418,864
-0.28549426351975254,0.49416676653861835,0.681310760353538,1.6795335557999362,-0.37857891381214337,1.8135950365776816,-0.014495016828056225,0.78581365326077,-0.5691719944139023,0.681310760353538,-0.3473913363783723,2.073867908502337,5.583564036632601,-0.13345627056560203,0.2167382414483214
2,640
Membrane lipid catabolic process
7
10
2.035116
0.041839
P04066,P06865,P50897,Q99735,P04062,P06280,O95470
Processes and pathways
GO Biological process
msigdb_gobp
96,128,34,586,514,147,397
397,514,96,147,128,1174,578,34,731,586
0.7075984308018949,0.5212446036040174,1.879622475578631,1.4029341761024565,1.5886225408277,-0.014495016828056225,0.43965797637879195,3.315124122100504,0.3012707091060534,0.43965797637879195
2,640
Proton transporting v type atpase complex
6
11
2.020252
0.043357
Q9Y487,Q8N511,P61421,Q15904,P36543,Q93050
Localization
GO Cellular component
msigdb_gocc
107,202,201,404,431,59
429,755,431,1282,201,404,202,59,1466,107,589
0.6549134221410868,0.2732207890233398,0.6549134221410868,-0.07368673938911026,1.1631283339474305,0.7075984308018949,1.1631283339474305,2.4864313476536455,-0.16356174978123925,1.8135950365776816,0.43965797637879195
2,640
Nuclear transcribed mrna catabolic process deadenylation dependent decay
6
25
2.015347
0.043868
Q9UIV1,O60506,Q14103,Q9H074,Q969T7,P67809
Processes and pathways
GO Biological process
msigdb_gobp
204,112,179,214,22,85
2534,112,1211,1125,283,989,1589,85,2317,1926,1087,179,1499,1974,1836,22,1510,1458,214,1667,1108,2278,1943,204,1519
-1.2889538712883826,1.7245233122626071,-0.0440194452758567,0.014888098811455428,0.9140721885646405,0.10220470852455128,-0.2547810983342171,2.0311875124734295,-0.7994837407245226,-0.44144157913135773,0.044131428334298,1.2601167830969409,-0.1938165802874622,-0.4731205436056062,-0.37857891381214337,3.762377345469554,-0.1938165802874622,-0.16356174978123925,1.138652142304504,-0.28549426351975254,0.044131428334298,-0.7327661943575732,-0.44144157913135773,1.1631283339474305,-0.1938165802874622
2,640
Organic anion transmembrane transporter activity
6
23
2.015319
0.043871
P41440,Q9H2D1,Q9UBX3,Q8TB61,P53985,Q99808
Functions
GO Molecular function
msigdb_gomf
68,37,302,300,178,81
778,1470,1371,1736,2125,1327,2308,1865,68,178,1647,1448,1549,2539,300,699,81,37,669,302,1313,1724,317
0.24504373849492278,-0.1938165802874622,-0.13345627056560203,-0.3473913363783723,-0.6015342284507788,-0.10349847880370376,-0.7994837407245226,-0.40992835459390864,2.283296003247575,1.2601167830969409,-0.28549426351975254,-0.16356174978123925,-0.22422245534187135,-1.2889538712883826,0.888626030424664,0.3291947939041686,2.0951066247996866,3.2077674049317846,0.3569943181163455,0.888626030424664,-0.07368673938911026,-0.31636373677520574,0.8630780347854784
2,640
Regulation of alternative mrna splicing via spliceosome
11
26
2.014055
0.044004
P51114,P09651,Q8IY67,P62995,Q9BWF3,P51116,P38159,Q9UHX1,Q92841,Q06787,Q07666
Processes and pathways
GO Biological process
msigdb_gobp
67,413,508,166,236,268,113,54,510,332,333
1120,413,909,870,1077,1812,113,2092,67,268,835,166,539,2317,332,333,1289,2271,508,510,1603,1666,236,54,646,706
0.014888098811455428,0.681310760353538,0.1597365361720637,0.18830296043822092,0.044131428334298,-0.37857891381214337,1.7245233122626071,-0.5691719944139023,2.32441261854729,0.9646626483533066,0.2167382414483214,1.3080720054464956,0.49416676653861835,-0.7994837407245226,0.8116727965909163,0.8116727965909163,-0.07368673938911026,-0.7327661943575732,0.5482062652881979,0.5482062652881979,-0.2547810983342171,-0.28549426351975254,1.0646610295240406,2.605465879915359,0.3846705364156224,0.3291947939041686
2,640
Secondary alcohol metabolic process
9
37
2.008967
0.044541
Q15392,P48735,P37268,Q9UBM7,Q14739,O75874,Q9BQE5,Q8WTV0,O15118
Processes and pathways
GO Biological process
msigdb_gobp
4,5,7,39,110,20,53,26,183
183,2482,1626,20,348,1372,1908,514,1574,1576,500,1530,1080,7,1697,1434,5,1485,1818,433,2490,518,1646,2415,2323,336,110,2603,4,1651,227,26,2362,53,2610,39,672
1.2360055619672616,-1.1094088346960982,-0.28549426351975254,3.8287611776161348,0.78581365326077,-0.13345627056560203,-0.44144157913135773,0.5212446036040174,-0.2547810983342171,-0.2547810983342171,0.5482062652881979,-0.22422245534187135,0.044131428334298,4.50638025156063,-0.31636373677520574,-0.16356174978123925,4.958809583957812,-0.1938165802874622,-0.37857891381214337,0.6549134221410868,-1.1094088346960982,0.5212446036040174,-0.28549426351975254,-0.9352177409809121,-0.7994837407245226,0.8116727965909163,1.7469038463164606,-1.863839644810072,5.195749907486007,-0.28549426351975254,1.0894193056981731,3.6953724657069063,-0.8331261590690011,2.605465879915359,-2.0691897186203922,3.1170308257343273,0.3569943181163455
2,640
Negative regulation of mrna processing
8
18
2.003839
0.045087
P18615,P61978,P38159,O75494,P22626,Q13242,Q07021,P98175
Processes and pathways
GO Biological process
msigdb_gobp
599,165,113,328,118,220,435,539
777,1120,939,328,599,118,991,1077,113,165,539,435,629,838,220,1289,843,1453
0.24504373849492278,0.014888098811455428,0.13103758702225834,0.8116727965909163,0.41222468387452377,1.6795335557999362,0.10220470852455128,0.044131428334298,1.7245233122626071,1.3080720054464956,0.49416676653861835,0.6549134221410868,0.3846705364156224,0.2167382414483214,1.1140827362508994,-0.07368673938911026,0.2167382414483214,-0.16356174978123925
2,640
Protein hydroxylation
6
14
1.99637
0.045894
Q92791,O15460,O75718,Q9NWT6,Q32P28,Q96AY3
Processes and pathways
GO Biological process
msigdb_gobp
66,170,139,181,210,157
821,170,139,1572,218,2102,1397,2291,210,66,157,1461,2366,181
0.2167382414483214,1.2841386816100955,1.4731860089006816,-0.2547810983342171,1.1140827362508994,-0.5691719944139023,-0.13345627056560203,-0.7660312248149689,1.138652142304504,2.385623388621299,1.355675872407539,-0.16356174978123925,-0.8331261590690011,1.2601167830969409
2,640
Membrane lipid metabolic process
7
30
1.963635
0.049572
P06865,P04066,P50897,Q06136,P16278,Q8NBX0,Q8NCC3
Processes and pathways
GO Biological process
msigdb_gobp
128,96,34,3,137,87,55
1367,651,1951,397,514,96,147,128,678,1174,137,578,830,34,3,731,355,87,55,388,1350,2401,586,2494,2610,545,365,1791,1988,2303
-0.13345627056560203,0.3569943181163455,-0.4731205436056062,0.7075984308018949,0.5212446036040174,1.879622475578631,1.4029341761024565,1.5886225408277,0.3291947939041686,-0.014495016828056225,1.5196047890008562,0.43965797637879195,0.2167382414483214,3.315124122100504,5.478539401482258,0.3012707091060534,0.78581365326077,2.0097448491460064,2.5660176085751587,0.7337774627197764,-0.10349847880370376,-0.9009906171012709,0.43965797637879195,-1.1094088346960982,-2.0691897186203922,0.49416676653861835,0.78581365326077,-0.3473913363783723,-0.4731205436056062,-0.7660312248149689
2,640
Predicted membrane proteins
111
453
4.216065
0.000025
Q99720,Q06136,O43772,Q9UIQ6,Q15363,Q8WTV0,Q70HW3,Q8IXU6,Q9UBM7,Q5BJF2,Q99805,Q8NCC3,Q9Y282,Q15392,Q9BQE5,O95831,Q9Y619,P41440,Q96CP7,Q9Y3B3,O43731,Q6ZT21,P62942,P42694,P43307,Q9UBV2,Q99808,Q9UBX3,Q14789,Q9Y2R0,Q9BVK6,Q9NR28,O95070,Q16611,Q99595,O43674,Q8N511,Q8NC54,Q9HD20,P24390,P30519,Q6P4Q7,Q92804,Q15629,Q93050,Q15904,P49755,P11117,O94966,Q52LJ0,Q8NBX0,P31350,O14936,Q8IV08,O60725,Q16799,Q9NS69,Q9H490,Q2TAA5,Q15631,P60468,O15127,O00461,Q16850,O75964,Q8IYS2,O75298,Q9Y262,O75306,P49257,P36551,O60830,Q8NBN3,Q9Y487,Q9NR77,Q9H6H4,Q9BTW9,P42892,O75352,Q96K12,P02786,O43676,Q96NB2,Q9BUB7,Q86Y82,Q8N2K0,Q567V2,Q03519,O95168,P35080,Q8NCH0,P09601,O43169,O75845,O95674,Q9NPR9,Q8NF37,Q86XL3,P49841,P10321,Q14534,Q5VW38,Q96RQ1,Q14318,O94919,P51003,P51812,Q9Y3A6,P49069,P35670,Q9NPL8
Functions
Protein Atlas Protein class
protein_atlas_protein_class
0,2,3,4,5,10,12,21,23,24,26,27,29,36,44,46,47,49,50,53,54,58,60,65,68,73,74,84,86,90,102,103,105,112,115,119,121,122,125,123,127,135,136,144,146,145,143,141,139,153,154,152,149,168,172,182,185,184,183,181,193,189,187,202,198,214,207,227,219,234,233,231,253,260,258,257,255,245,244,270,264,262,302,305,299,300,298,293,289,291,319,311,329,332,333,362,356,354,351,347,381,385,393,380,365,375,376,416,400,398,433
2130,2246,1916,1755,587,556,187,1385,966,2407,1143,642,2579,1144,2347,2063,438,149,2502,2165,2329,189,439,2522,1711,643,1145,329,1050,2408,1846,119,262,54,1004,1333,3,1571,2523,2409,1712,1990,518,172,231,1390,1391,207,219,244,1952,1439,1758,679,1148,1241,1242,1335,332,2374,198,708,1714,1620,1149,2607,365,139,105,289,709,2132,1150,2134,791,1715,333,2608,46,710,1492,595,264,793,1716,1442,2286,2622,1805,2066,1153,622,2249,1622,311,2439,2068,347,141,1108,1890,1009,494,1920,1340,1668,2376,931,830,1401,1296,1402,2136,2170,123,887,834,2504,524,127,152,1770,1298,2202,291,1583,468,398,233,1771,2041,1017,49,65,838,245,68,751,1063,1588,1350,400,234,143,351,565,444,1407,375,2466,935,2274,2309,1819,376,686,1354,2427,1630,2142,1206,1857,840,1680,193,533,938,2144,60,2528,1165,2494,2381,1859,939,2180,293,537,2,723,1634,1069,1860,2614,2076,603,1414,1862,2049,422,801,1784,1416,2311,1541,1823,661,1360,1542,2442,1072,1073,380,381,1365,86,1638,2363,1734,5,540,36,144,181,804,2483,145,944,2187,112,1459,1689,182,202,183,1167,2534,1788,541,808,153,1935,298,24,1826,2289,2612,1215,1421,2541,2314,385,1217,1368,1311,1423,906,135,852,1548,1646,2484,58,2519,12,634,2508,504,690,2316,855,2386,354,1937,299,168,1079,810,1372,769,21,2157,214,2456,1081,300,2549,121,1737,1313,1603,253,1738,154,2293,122,27,319,1314,356,2084,578,2117,813,987,1872,1170,857,10,858,1908,2367,910,2260,2191,1792,2419,545,546,136,146,1219,429,1466,1032,1086,1220,2368,50,2261,2193,1173,2119,2120,453,507,270,667,430,1982,1606,302,2211,393,1559,1515,2057,2091,1376,115,1560,0,1132,26,74,2473,729,44,914,1744,1280,2295,2296,1607,255,1471,2369,305,1429,1703,2630,1746,1517,102,2423,2500,2021,1940,639,613,1473,731,1038,1181,2604,866,1658,1182,1431,1183,184,509,257,1833,2298,1795,125,670,1876,1185,1609,433,362,2164,1137,103,258,185,1834,1042,1611,779,2282,1187,1283,1432,1322,732,1478,1835,1094,2434,2390,1188,23,1946,2620,73,84,2475,998,1381,781,783,961,4,675,1284,2556,227,1614,1986,29,586,2449,90,2216,2406,416,53,1382,2425,1098,260,1435,2219,1328,1881,47,1002,1663,2557,738
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2,631
Mitotic g1 phase and g1 s transition
20
67
4.10947
0.00004
O00233,P00374,P49721,P49720,P31350,P30153,P11802,P28072,Q9NR33,Q13309,Q9Y619,P20618,P28070,O00487,Q9UL46,P63151,P25789,P28074,P25788,Q99436
Processes and pathways
Reactome Pathways
msigdb_reactome
132,9,18,142,152,280,279,34,38,294,47,59,62,188,206,99,350,106,349,394
515,874,132,188,1843,825,929,9,1054,1993,1107,1763,2168,279,682,1342,884,1445,59,833,1813,1011,749,349,350,628,973,62,34,106,280,152,835,1673,1201,1347,496,1893,837,1115,1066,1301,142,18,1589,1894,2073,378,937,1858,1257,1593,99,658,1068,1597,1416,294,2361,1903,943,394,2091,38,206,922,47
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,4.004804150480747,0.21377219628069816,-0.544579561175527,0.1808662269600239,-0.31336929154874354,-0.7461197124067016,0.9511996966722966,0.49703301170235065,0.011628382363652217,0.3424442560190503,-0.058326639732175146,2.0274549169815406,0.3739010427175194,-0.3510973783434665,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.5570467687489573,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,0.9511996966722966,1.257791335055367,0.3739010427175194,-0.23888251175943867,0.11412915938872559,0.011628382363652217,0.6741423628769925,-0.4275222886859329,0.3739010427175194,0.1808662269600239,0.21377219628069816,0.04611947228614343,1.2822041225107923,3.3458384043052356,-0.16568914771639728,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,1.4948164960337653,0.5271655315673739,0.21377219628069816,-0.16568914771639728,-0.023187036139176026,0.9244343611620436,-1.085306619758222,-0.4275222886859329,0.3107081753546436,0.8153380062854007,-0.624229536412293,2.47472917852122,1.107748671810519,0.3424442560190503,2.2204944858377984
2,631
Transport
108
413
3.875555
0.000106
Q99720,P35754,O43772,Q92734,Q15363,Q07955,Q15388,Q70HW3,Q8IXU6,Q15437,Q9Y282,Q9BQE5,Q9Y619,P41440,Q9UI26,Q9Y3B3,O43731,Q15436,Q6DKK2,Q9H4A6,A0AVF1,Q99808,Q9Y6B6,Q9UBX3,P21796,O60684,Q92973,Q9BVK6,O95070,Q99595,O43674,Q9HD20,P24390,Q9H2D1,Q6P4Q7,Q15629,Q93050,Q15904,P49755,P52294,P61421,P20338,Q96P70,Q9NS69,P18085,P60468,Q9Y2T2,Q8N4H5,O15127,P46379,O00461,O75964,Q9Y678,P21281,O75306,Q9Y3A3,P49257,O60830,Q9Y487,Q9BW83,O75352,Q9P253,P45880,O43676,P83436,O96000,Q96NB2,Q86Y82,P54920,Q03519,O95168,Q9BRG1,P36405,Q8WVM8,O43169,P36543,O15498,P21283,Q96PU8,Q8WUX9,Q96RQ1,Q9NR31,Q9Y3A6,Q7L5D6,P49069,P37198,P35670,O43264,Q9Y4C2,P52292,Q12907,Q96KP1,Q96T51,Q9HD26,Q9UBQ0,Q16718,P50416,O14925,Q06787,Q96SU4,Q8TEX9,Q9NZZ3,Q9UJY5,O00471,O75251,P51153,P62820,P11717
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
0,497,3,546,5,538,540,12,21,22,29,44,47,49,52,53,54,61,63,67,71,74,82,84,85,94,100,102,105,115,119,125,123,130,135,144,146,145,143,159,167,162,175,185,179,193,197,194,189,192,187,198,230,222,219,243,234,231,260,256,244,272,267,262,282,275,302,299,292,293,289,323,312,343,329,337,328,335,392,390,393,412,416,407,400,399,398,395,437,420,422,454,455,459,462,450,444,438,448,483,481,486,487,464,466,498,500,494
71,2130,1916,2462,587,1142,1951,1003,824,2196,187,464,966,2595,2347,438,1386,787,925,788,2165,2329,189,590,328,2537,329,2331,395,558,2408,1802,1388,119,262,1146,1147,54,1756,1004,3,1571,1884,1617,1917,1713,94,967,1803,1192,2221,231,1390,1391,466,219,1240,244,1952,1758,645,620,1194,593,1573,1195,198,878,968,1394,1244,105,289,2031,709,2132,1150,1151,1007,2101,1491,275,1104,595,1760,2286,2622,1805,647,622,2249,1622,1294,2068,1108,1890,494,1920,1340,2538,1154,1249,1401,179,1578,1402,1156,162,2037,222,335,85,1671,1158,1345,653,831,627,123,887,2201,524,714,1817,835,1924,1254,2002,398,497,312,1060,337,399,1853,597,598,654,49,1114,1626,526,267,192,1675,1725,1500,892,400,234,1450,143,2586,2399,444,1204,1117,498,2466,2274,2309,1819,420,159,2230,1205,2141,1408,2427,1678,1630,292,2142,977,1895,1206,1356,978,193,936,1411,719,1896,532,167,533,1631,797,1412,500,1538,1777,1778,1260,2147,1822,282,2110,2381,2357,2180,293,448,538,2181,2204,1359,846,1598,2049,422,801,1784,2311,2205,661,1417,2112,1455,1684,2402,903,631,1266,5,540,61,22,144,2483,145,944,1688,450,1689,575,541,1270,2289,1216,1217,2152,63,946,1547,1423,906,135,12,853,407,1868,854,1871,1937,299,1509,21,1081,2159,194,2549,1313,1828,2160,948,1314,1029,2366,2525,813,2343,1464,857,481,1275,1873,390,343,1276,1426,2419,546,772,100,146,950,1466,1033,2088,1742,1554,1981,1173,692,1556,816,454,302,175,392,2056,393,2593,483,455,1376,1316,115,0,693,74,1175,1516,44,323,1280,2295,1471,1429,1703,1746,102,2163,775,256,1705,612,2486,2511,1472,1227,1038,1228,1181,130,866,1431,1230,67,1608,955,1833,1039,1795,125,459,699,2554,1185,412,700,185,1944,2474,1945,1139,1322,2283,1478,486,1094,272,2390,1188,555,462,1379,84,2475,1381,2127,52,961,1565,1044,487,2302,675,2195,1948,1566,2501,1879,1284,585,1880,735,29,586,821,2578,197,243,416,53,2027,260,437,1140,1662,1141,1000,1329,1287,47,230,872,82,2557,2521,1330,1664
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2,631
Signaling by the b cell receptor bcr
16
45
3.771849
0.000162
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,O00221,P49721,P49720,P62993,Q99436,O43865,P20618,P62942,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,48,18,142,210,394,177,59,60,62
48,515,874,132,188,1843,825,177,929,594,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,60,210,658,1068,1070,1416,2361,1507,943,394,2091,206,922
2.2016422601947694,0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,1.15845820052481,0.3107081753546436,0.5866809767008758,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,2.0274549169815406,1.0821243548255537,0.5271655315673739,0.21377219628069816,0.21377219628069816,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Protease
21
72
3.770467
0.000163
P42892,Q9UIQ6,P42785,Q92905,Q96FW1,O94966,P55786,P28072,P50579,Q9NZ08,Q9H8M7,Q9BYT8,Q9H3G5,Q5JRX3,O00487,P16870,Q9HB40,P52888,P28074,Q01804,Q99436
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
245,4,7,269,147,139,33,34,174,55,326,325,196,66,188,208,93,97,106,353,394
588,188,1047,1050,1489,706,1335,708,139,1889,493,1921,1850,208,34,106,2396,1346,1499,1255,7,245,1449,599,174,97,2230,1354,1537,33,2528,2494,842,353,1504,1364,1638,1213,1825,66,1735,1550,504,1869,1168,1170,269,1172,814,147,773,611,860,2057,394,1911,1279,409,325,196,550,2241,326,93,1234,1186,1092,55,4,1140,2219,1615
0.5866809767008758,1.13319242501366,0.21377219628069816,0.21377219628069816,-0.09379028637419248,0.46664484400905687,0.011628382363652217,0.46664484400905687,1.2822041225107923,-0.4275222886859329,0.6741423628769925,-0.46621885306434724,-0.3891484207838882,1.0821243548255537,2.561425042425346,1.47179933358734,-1.17331342279577,0.011628382363652217,-0.09379028637419248,0.08028608865991266,4.1079376469458575,1.0041412915640857,-0.058326639732175146,0.5866809767008758,1.183548528852841,1.4948164960337653,-0.8289885581393346,0.011628382363652217,-0.12957783544472734,2.679467443709186,-1.6802476075658623,-1.4914291062743523,0.3739010427175194,0.8429236851350608,-0.09379028637419248,0.011628382363652217,-0.2021240853281833,0.11412915938872559,-0.3510973783434665,1.865329260145266,-0.2759642918046235,-0.12957783544472734,0.6741423628769925,-0.3891484207838882,0.14765384784078572,0.14765384784078572,0.977767688006064,0.14765384784078572,0.40508352216113896,1.2822041225107923,0.4359965476908903,0.5866809767008758,0.3739010427175194,-0.5842434527420278,0.8153380062854007,-0.4275222886859329,0.08028608865991266,0.7875391296424109,0.8974686565746289,1.13319242501366,0.6452247828693638,-0.8289885581393346,0.8974686565746289,1.5404174998791007,0.11412915938872559,0.14765384784078572,0.21377219628069816,2.0864437380032115,4.954689535317153,0.1808662269600239,-0.7873933421725157,-0.16568914771639728
2,631
Dna replication pre initiation
16
58
3.658263
0.000254
O60684,P28072,O00233,O00487,Q9NR33,Q9UL46,P25789,P28074,P25788,Q9Y619,P49721,P49720,Q99436,P20618,P28070,P52294
Processes and pathways
Reactome Pathways
msigdb_reactome
94,34,132,188,38,206,350,106,349,47,18,142,394,59,62,159
515,874,132,188,1843,825,94,929,1763,884,2199,1445,59,833,1813,1011,749,349,350,628,973,62,34,106,1673,1201,1347,496,1893,1115,1066,1301,142,18,1589,1894,159,2073,378,937,1858,1257,1593,1728,759,1068,1597,1416,1903,1266,1507,943,394,2091,38,206,922,47
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,1.5176885982704214,0.3107081753546436,-0.31336929154874354,0.3424442560190503,-0.7873933421725157,-0.058326639732175146,2.0274549169815406,0.3739010427175194,-0.3510973783434665,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.5570467687489573,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.23888251175943867,0.11412915938872559,0.011628382363652217,0.6741423628769925,-0.4275222886859329,0.1808662269600239,0.21377219628069816,0.04611947228614343,1.2822041225107923,3.3458384043052356,-0.16568914771639728,-0.4275222886859329,1.2332126975583004,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,-0.2759642918046235,0.4359965476908903,0.21377219628069816,-0.16568914771639728,-0.023187036139176026,-0.4275222886859329,0.08028608865991266,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,2.47472917852122,1.107748671810519,0.3424442560190503,2.2204944858377984
2,631
Alcohol metabolic process
11
67
3.599402
0.000319
Q9BY49,O60762,Q15392,P48449,P00374,Q8WTV0,O75874,Q9BQE5,P48735,Q9UBM7,P30837
Processes and pathways
GO Biological process
msigdb_gobp
129,190,36,8,9,10,41,44,17,23,56
1239,2165,1711,2267,190,332,41,878,2247,1440,9,1492,1848,621,369,1623,596,883,747,2198,830,1344,1345,56,2339,1583,1771,1773,1349,8,17,1351,1535,934,935,1629,686,2044,600,1631,2357,2046,1120,687,1824,405,1023,381,1365,2207,36,804,202,986,451,10,1911,2346,44,638,129,1181,1476,554,23,1749,999
0.08028608865991266,-0.7461197124067016,-0.2759642918046235,-0.9131432773169984,1.13319242501366,0.8702994873684097,2.4038695750039927,0.3424442560190503,-0.8709052422195689,-0.058326639732175146,4.004804150480747,-0.09379028637419248,-0.3891484207838882,0.5570467687489573,0.8153380062854007,-0.2021240853281833,0.5866809767008758,0.3424442560190503,0.4359965476908903,-0.7873933421725157,0.3739010427175194,0.011628382363652217,0.011628382363652217,2.06688635784378,-1.041784332284214,-0.16568914771639728,-0.31336929154874354,-0.31336929154874354,0.011628382363652217,4.016404489026196,3.521809624851483,0.011628382363652217,-0.12957783544472734,0.3107081753546436,0.3107081753546436,-0.2021240853281833,0.49703301170235065,-0.5842434527420278,0.5866809767008758,-0.2021240853281833,-1.085306619758222,-0.5842434527420278,0.1808662269600239,0.49703301170235065,-0.3510973783434665,0.7875391296424109,0.24637748849157123,0.8153380062854007,0.011628382363652217,-0.7873933421725157,2.5096531511230316,0.40508352216113896,1.107748671810519,0.278687675691609,0.7312880952006297,3.9225804558905155,-0.4275222886859329,-1.041784332284214,2.3498130031826134,0.5570467687489573,1.330541201726474,0.14765384784078572,-0.058326639732175146,0.6452247828693638,3.102383344071522,-0.2759642918046235,0.278687675691609
2,631
Antigen processing cross presentation
16
49
3.595045
0.000324
P28072,O00233,Q9UIQ6,O00487,Q9UL46,P25789,P28074,P25788,P10321,P60468,Q03519,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,4,188,206,350,106,349,347,193,293,18,142,394,59,62
587,515,874,132,188,1843,825,1758,929,793,2033,347,1445,59,1011,749,349,350,1013,973,62,34,106,2353,1893,1115,1066,142,18,1894,2073,193,378,937,533,1858,1257,1593,293,1068,2049,1416,1507,943,394,2091,4,206,922
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2,631
Downstream signaling events of b cell receptor bcr
14
43
3.562044
0.000368
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,O00221,P49721,P49720,Q99436,P20618,P62942,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,48,18,142,394,59,60,62
48,515,874,132,188,1843,825,929,594,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,60,658,1068,1070,1416,2361,1507,943,394,2091,206,922
2.2016422601947694,0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.5866809767008758,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,2.0274549169815406,0.5271655315673739,0.21377219628069816,0.21377219628069816,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Endoplasmic reticulum
107
396
3.553131
0.000381
Q99720,Q06136,Q15363,P48449,P26885,Q9UMX5,Q15437,Q9UBM7,Q5BJF2,P07099,Q9Y282,Q96AY3,Q15392,P80303,Q9BQE5,Q14257,Q9Y3B3,O43731,Q9NZ08,P62942,Q15436,P43307,Q9H2J4,Q9UBV2,Q92791,Q9UQB8,Q9Y6B6,Q9BVK6,O95070,O00429,Q16611,Q9NRR5,Q9NWM8,Q8N511,Q9HD20,P24390,P30519,Q15629,Q15904,P49755,O94966,O75718,Q8IV08,P30626,O43852,O60725,Q9BTY2,Q16799,Q9H490,Q2TAA5,Q15631,O43865,P60468,O60762,Q16850,Q01105,O75298,Q9Y678,Q9BRR6,Q02818,P49257,Q9Y244,Q9H6H4,O75352,Q8N2K0,Q32P28,Q03519,P20073,P52306,P09601,Q8WVM8,O75845,P28161,O75503,O15498,O95674,Q9H488,Q8NF37,Q86XL3,P10321,Q14534,Q96RQ1,Q14318,O95881,Q99797,Q9NR31,Q9UMX0,Q9Y3A6,P49069,O43264,Q96KC8,Q969V3,P52292,Q12907,P27361,Q8TC12,P08754,O15173,P60953,Q9Y2B0,O43390,P35613,Q03001,Q7Z2K6,Q96JJ7,Q9H8Y8,P10619
Localization
GO Cellular component
msigdb_gocc
0,2,5,8,16,20,22,23,24,25,29,31,36,43,44,51,53,54,55,60,61,68,70,73,77,78,82,102,105,108,112,117,118,121,125,123,127,144,145,143,139,158,168,163,161,172,176,182,184,183,181,177,193,190,202,200,207,230,225,237,234,259,257,244,300,296,293,290,315,311,343,332,336,331,328,333,360,356,354,347,381,393,380,367,409,412,415,416,400,395,430,429,420,422,419,451,441,439,445,488,465,468,474,504,507,511,493
2130,2246,1916,1436,2266,556,108,1385,1842,642,2579,2063,2502,788,2165,439,2522,1711,705,328,395,465,1290,1050,1846,1146,54,161,177,1990,559,172,190,1803,207,2566,244,1758,331,1241,158,1335,332,2374,1714,2223,968,1243,560,2247,139,1244,105,709,2134,1008,791,2101,1715,333,2608,1992,367,1667,1492,1848,793,1106,1716,1442,2286,970,1107,25,1995,1806,441,311,2225,347,493,1532,2335,1110,2103,1922,2104,830,1401,1296,290,1111,1446,1158,2170,1533,1403,123,1404,2379,1767,16,834,419,1580,750,1013,2504,336,1721,2338,1497,1892,2353,127,715,163,2040,1298,2202,1254,1583,468,2589,1771,2041,1017,1534,838,68,2412,2308,2398,1063,1500,8,1350,892,400,2380,234,1855,143,565,2413,1407,2466,935,1819,420,315,1590,1205,2141,1354,1678,1895,1679,1355,756,840,193,936,445,1775,1411,1896,532,2232,2143,533,938,1631,797,2177,2467,1962,500,1632,1164,1259,60,2109,1260,2528,2494,43,2505,2516,602,1859,200,1261,2047,237,2401,474,293,1210,2,1782,1634,603,1862,1931,422,801,1969,1784,2441,1824,1360,1542,1072,51,380,381,1902,2079,1365,1266,1638,2052,2470,1734,1166,5,1122,36,2364,61,22,144,181,1867,804,145,112,182,202,183,296,1788,1935,24,1826,2289,1545,1368,1547,1311,1423,2113,2519,634,504,691,855,2386,354,1509,168,2279,810,2157,2456,300,2549,121,1737,1313,1603,1696,577,2189,356,1315,2084,578,2085,813,451,2343,1170,1030,1978,857,1873,343,910,2260,2191,546,77,1084,579,1219,429,1466,1086,1220,2368,31,2261,2119,692,507,430,1606,2211,393,1559,1829,1911,1560,0,1132,409,2473,44,225,1280,2296,1607,176,2369,1429,1703,1746,1517,102,2021,696,1181,70,614,1431,360,184,257,1320,511,2405,1795,125,2554,1185,1609,2164,412,117,1834,1944,118,1747,1432,55,1322,1835,2434,2390,1659,1188,555,997,23,2323,2620,73,1380,1381,1480,2489,675,415,20,820,1284,1751,78,259,29,821,488,2406,999,416,53,2245,2532,1327,1328,230,1663,82,1045
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2,631
Cdt1 association with the cdc6 orc origin complex
13
38
3.525562
0.000423
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,Q9Y619,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,47,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,1507,943,394,2091,206,922,47
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503,2.2204944858377984
2,631
Copii coated er to golgi transport vesicle
14
30
3.516546
0.000437
Q15363,Q9BVK6,P10321,O95070,P49755,Q9NR31,Q9Y6B6,Q9Y3A6,Q15436,Q9Y3B3,Q15437,Q96RQ1,P49257,Q9Y282
Localization
GO Cellular component
msigdb_gocc
5,102,347,105,143,412,82,416,61,53,22,393,234,29
788,1803,2566,1758,1244,105,2101,793,347,234,143,1354,1678,422,1784,5,61,22,1788,1545,1466,393,102,412,1380,29,416,53,82,1045
0.40508352216113896,-0.3510973783434665,-2.022972918699234,-0.31336929154874354,0.08028608865991266,1.47179933358734,-0.6645376888850335,0.40508352216113896,0.8429236851350608,1.0303233973076291,1.2822041225107923,0.011628382363652217,-0.23888251175943867,0.759523653936807,-0.31336929154874354,4.86328444949437,2.0274549169815406,3.1756606722953644,-0.31336929154874354,-0.12957783544472734,-0.058326639732175146,0.8153380062854007,1.4948164960337653,0.7875391296424109,0.011628382363652217,2.841800548164946,0.7875391296424109,2.1058970915870394,1.6299370577151888,0.24637748849157123
2,631
Uch proteinases
13
45
3.490415
0.000482
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,Q8NB78,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,13,18,142,394,59,62
515,874,132,188,1843,490,825,929,1105,1445,59,2106,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,2175,1894,2073,378,937,1858,1257,1593,1068,1416,1507,943,1212,13,394,2091,206,922,1237,1615
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.6741423628769925,0.3739010427175194,0.3107081753546436,0.1808662269600239,-0.058326639732175146,2.0274549169815406,-0.6645376888850335,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.7461197124067016,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.11412915938872559,3.5873366483495683,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503,0.11412915938872559,-0.16568914771639728
2,631
Endoplasmic reticulum golgi intermediate compartment membrane
14
25
3.489005
0.000485
Q15363,Q9BVK6,O95070,Q15904,P49755,Q03519,P49257,Q9Y3A6,Q9Y3B3,O15498,Q8N511,Q9Y282,P24390,Q96RQ1
Localization
GO Cellular component
msigdb_gocc
5,102,105,145,143,293,234,416,53,328,121,29,123,393
328,1758,105,123,1013,234,143,2466,1354,1411,293,603,422,1784,5,145,1788,121,1466,393,102,694,29,416,53
0.8702994873684097,-0.31336929154874354,1.47179933358734,1.3544699048423925,0.24637748849157123,1.0303233973076291,1.2822041225107923,-1.3989382867201257,0.011628382363652217,-0.023187036139176026,0.9244343611620436,0.5866809767008758,0.759523653936807,-0.31336929154874354,4.86328444949437,1.2822041225107923,-0.31336929154874354,1.3782415831495038,-0.058326639732175146,0.8153380062854007,1.4948164960337653,0.49703301170235065,2.841800548164946,0.7875391296424109,2.1058970915870394
2,631
Cellular modified amino acid metabolic process
18
50
3.487447
0.000488
Q9H2D1,Q9NRN7,P50416,O75874,P00374,P49419,Q8N2K0,O60725,Q14353,Q8IYS1,P78417,Q9H7Z7,P41440,P28161,Q04760,Q8NCC3,P34897,Q9UHG3
Processes and pathways
GO Biological process
msigdb_gobp
130,131,444,41,9,134,300,172,201,505,236,551,49,336,536,27,371,30
1003,1385,644,172,41,2374,9,930,1760,1398,1993,1339,1623,1849,1764,1957,1341,830,523,1157,627,1767,336,1405,371,49,891,1065,976,1350,2006,134,444,236,536,201,1548,505,300,27,2117,1031,1911,1132,1517,130,551,131,30,1753
0.24637748849157123,-0.023187036139176026,0.5271655315673739,1.183548528852841,2.4038695750039927,-1.129149687086767,4.004804150480747,0.3107081753546436,-0.31336929154874354,-0.023187036139176026,-0.544579561175527,0.011628382363652217,-0.2021240853281833,-0.3891484207838882,-0.31336929154874354,-0.5052379861113006,0.011628382363652217,0.3739010427175194,0.6452247828693638,0.14765384784078572,0.5570467687489573,-0.31336929154874354,0.8702994873684097,-0.023187036139176026,0.8153380062854007,2.2016422601947694,0.3424442560190503,0.21377219628069816,0.278687675691609,0.011628382363652217,-0.544579561175527,1.3064533352461962,0.7312880952006297,1.0303233973076291,0.6452247828693638,1.107748671810519,-0.12957783544472734,0.6741423628769925,0.9244343611620436,2.9358813459906243,-0.6645376888850335,0.24637748849157123,-0.4275222886859329,0.1808662269600239,-0.09379028637419248,1.330541201726474,0.6452247828693638,1.330541201726474,2.745260322918709,-0.2759642918046235
2,631
Secondary alcohol metabolic process
6
37
3.471527
0.000518
Q15392,P48449,O75874,Q8WTV0,P48735,Q9UBM7
Processes and pathways
GO Biological process
msigdb_gobp
36,8,41,10,17,23
2165,2267,332,41,878,2247,1492,1848,1623,883,830,1345,1583,1771,1773,8,17,1351,1535,1629,686,1631,2357,2046,1023,381,1365,2207,36,804,202,10,2346,44,1181,23,1749
-0.7461197124067016,-0.9131432773169984,0.8702994873684097,2.4038695750039927,0.3424442560190503,-0.8709052422195689,-0.09379028637419248,-0.3891484207838882,-0.2021240853281833,0.3424442560190503,0.3739010427175194,0.011628382363652217,-0.16568914771639728,-0.31336929154874354,-0.31336929154874354,4.016404489026196,3.521809624851483,0.011628382363652217,-0.12957783544472734,-0.2021240853281833,0.49703301170235065,-0.2021240853281833,-1.085306619758222,-0.5842434527420278,0.24637748849157123,0.8153380062854007,0.011628382363652217,-0.7873933421725157,2.5096531511230316,0.40508352216113896,1.107748671810519,3.9225804558905155,-1.041784332284214,2.3498130031826134,0.14765384784078572,3.102383344071522,-0.2759642918046235
2,631
Exopeptidase activity
14
32
3.42002
0.000626
P55786,Q9UIQ6,P42785,P10619,Q969V3,Q7Z2K6,Q8IYS1,P50579,P02786,P36551,Q9HB40,Q9NZ08,P16870,Q9H3G5
Functions
GO Molecular function
msigdb_gomf
33,4,7,493,429,504,505,174,264,233,93,55,208,196
1047,1335,708,264,1889,493,1921,208,2396,1346,233,7,174,1354,33,1022,1504,504,1869,505,1031,429,860,817,196,550,93,1234,1186,1092,55,4
0.21377219628069816,0.011628382363652217,0.46664484400905687,0.977767688006064,-0.4275222886859329,0.6741423628769925,-0.46621885306434724,1.0821243548255537,-1.17331342279577,0.011628382363652217,1.0303233973076291,4.1079376469458575,1.183548528852841,0.011628382363652217,2.679467443709186,0.24637748849157123,-0.09379028637419248,0.6741423628769925,-0.3891484207838882,0.6741423628769925,0.24637748849157123,0.759523653936807,0.3739010427175194,0.40508352216113896,1.13319242501366,0.6452247828693638,1.5404174998791007,0.11412915938872559,0.14765384784078572,0.21377219628069816,2.0864437380032115,4.954689535317153
2,631
Defective cftr causes cystic fibrosis
13
41
3.41803
0.000631
P28072,O00233,O00487,Q9UL46,P25789,P28074,Q9UBV2,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,73,349,18,142,394,59,62
515,874,132,188,1843,825,929,2247,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,1895,378,937,1858,1257,1593,1068,1416,1507,943,394,2091,1429,73,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.8709052422195689,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,-0.4275222886859329,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,-0.023187036139176026,1.781481931571495,1.107748671810519,0.3424442560190503
2,631
Abc transporter disorders
13
41
3.41803
0.000631
P28072,O00233,O00487,Q9UL46,P25789,P28074,Q9UBV2,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,73,349,18,142,394,59,62
515,874,132,188,1843,825,929,2247,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,1895,378,937,1858,1257,1593,1068,1416,1507,943,394,2091,1429,73,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.8709052422195689,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,-0.4275222886859329,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,-0.023187036139176026,1.781481931571495,1.107748671810519,0.3424442560190503
2,631
Regulation of runx2 expression and activity
14
43
3.394267
0.000688
P28072,O00233,O00487,Q9UL46,P49841,P25789,P28074,P25788,Q13309,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,351,350,106,349,294,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,1893,1586,1115,1066,142,18,351,1894,2073,378,937,1858,1257,1593,658,1068,1416,294,2361,1507,943,394,2091,206,820,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,-0.16568914771639728,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,0.8429236851350608,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.023187036139176026,0.9244343611620436,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.40508352216113896,0.3424442560190503
2,631
Orc1 removal from chromatin
14
48
3.386011
0.000709
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,Q13309,Q9Y619,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,294,47,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,833,1813,1011,749,349,350,973,62,34,106,1673,1201,1347,1893,1115,1066,142,18,1589,1894,2073,378,937,1858,1257,1593,658,1068,1416,294,2361,1903,1507,943,394,2091,206,922,47
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.3739010427175194,-0.3510973783434665,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.23888251175943867,0.11412915938872559,0.011628382363652217,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.16568914771639728,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.023187036139176026,0.9244343611620436,-1.085306619758222,-0.4275222886859329,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503,2.2204944858377984
2,631
Endoplasmic reticulum golgi intermediate compartment
18
44
3.368947
0.000755
Q15363,Q9BVK6,P80303,O95070,Q02818,Q15904,P49755,Q03519,P49257,Q9Y3A6,Q9Y3B3,Q14789,O15498,Q8N511,Q9Y678,Q9Y282,P24390,Q96RQ1
Localization
GO Cellular component
msigdb_gocc
5,102,43,105,237,145,143,293,234,416,53,86,328,121,230,29,123,393
2522,328,1758,105,1995,2033,123,1013,2202,234,143,2413,2466,1205,1354,1411,43,237,293,603,422,1784,86,1734,5,145,1788,1545,1509,121,1276,579,1466,393,102,694,1747,555,2489,29,416,53,230,1045
-1.6325636329473232,0.8702994873684097,-0.31336929154874354,1.47179933358734,-0.544579561175527,-0.5842434527420278,1.3544699048423925,0.24637748849157123,-0.7873933421725157,1.0303233973076291,1.2822041225107923,-1.217797716297186,-1.3989382867201257,0.11412915938872559,0.011628382363652217,-0.023187036139176026,2.3679204497279276,1.0303233973076291,0.9244343611620436,0.5866809767008758,0.759523653936807,-0.31336929154874354,1.5854529614565336,-0.2759642918046235,4.86328444949437,1.2822041225107923,-0.31336929154874354,-0.12957783544472734,-0.09379028637419248,1.3782415831495038,0.08028608865991266,0.6160723009781515,-0.058326639732175146,0.8153380062854007,1.4948164960337653,0.49703301170235065,-0.2759642918046235,0.6452247828693638,-1.445023740434061,2.841800548164946,0.7875391296424109,2.1058970915870394,1.0563168307418604,0.24637748849157123
2,631
ER-Golgi transport
21
51
3.358849
0.000783
Q92734,Q15363,P49755,Q9NR31,Q15437,P49069,Q9Y282,O43264,P54920,P18085,O43731,Q15436,Q8WVM8,Q9Y6B6,O15498,Q9Y678,O95070,P49257,Q96RQ1,P62820,P24390
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
546,5,143,412,22,400,29,395,292,179,54,61,343,82,328,230,105,234,393,500,123
788,328,395,54,1803,1758,1244,105,709,1150,2101,179,123,1254,1500,400,234,143,2466,1205,2141,1678,292,1411,797,500,801,2112,5,61,22,2289,1547,1868,1509,1828,343,546,1466,393,693,1795,412,1322,1188,555,29,821,2578,230,82
0.40508352216113896,0.8702994873684097,0.7875391296424109,2.0864437380032115,-0.3510973783434665,-0.31336929154874354,0.08028608865991266,1.47179933358734,0.46664484400905687,0.14765384784078572,-0.6645376888850335,1.15845820052481,1.3544699048423925,0.08028608865991266,-0.09379028637419248,0.7875391296424109,1.0303233973076291,1.2822041225107923,-1.3989382867201257,0.11412915938872559,-0.705167787937405,-0.23888251175943867,0.9244343611620436,-0.023187036139176026,0.40508352216113896,0.6741423628769925,0.40508352216113896,-0.6645376888850335,4.86328444949437,2.0274549169815406,3.1756606722953644,-0.9557025473106139,-0.12957783544472734,-0.3891484207838882,-0.09379028637419248,-0.3510973783434665,0.8702994873684097,0.6452247828693638,-0.058326639732175146,0.8153380062854007,0.49703301170235065,-0.31336929154874354,0.7875391296424109,0.04611947228614343,0.14765384784078572,0.6452247828693638,2.841800548164946,0.40508352216113896,-2.123764241801811,1.0563168307418604,1.6299370577151888
2,631
Regulation of hmox1 expression and activity
14
44
3.341423
0.000834
P28072,O00233,P09601,O00487,Q9UL46,P25789,P28074,P25788,Q13309,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,311,188,206,350,106,349,294,18,142,394,59,62
515,874,132,188,1843,825,929,311,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,658,1208,1068,1416,294,2361,2112,1507,943,1170,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.8974686565746289,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.11412915938872559,0.21377219628069816,-0.023187036139176026,0.9244343611620436,-1.085306619758222,-0.6645376888850335,-0.09379028637419248,0.3107081753546436,0.14765384784078572,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Protein methyltransferase activity
10
22
3.320034
0.0009
Q99873,Q9H7B4,Q9BV86,O60725,Q7L592,O96028,Q86X55,Q8NCA5,Q52LJ0,O60678
Functions
GO Molecular function
msigdb_gomf
303,6,11,172,81,140,387,389,153,330
1882,330,172,140,2136,1811,899,981,1418,1268,153,1508,81,1371,387,389,303,11,6,432,1564,960
-0.4275222886859329,0.8702994873684097,1.183548528852841,1.2822041225107923,-0.705167787937405,-0.3510973783434665,0.3424442560190503,0.278687675691609,-0.023187036139176026,0.08028608865991266,1.257791335055367,-0.09379028637419248,1.6299370577151888,0.011628382363652217,0.8153380062854007,0.8153380062854007,0.9244343611620436,3.8867815235067193,4.119223867396464,0.759523653936807,-0.12957783544472734,0.3107081753546436
2,631
Endopeptidase complex
15
55
3.314675
0.000917
P54725,P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q9H490,Q99436,P20618,P60900,P28070
Localization
GO Cellular component
msigdb_gocc
166,34,132,188,206,350,106,349,18,142,184,394,59,378,62
515,874,132,188,1843,825,558,1050,929,1761,1445,59,1011,749,349,350,973,62,34,106,1893,1255,1115,1066,142,18,1894,1537,166,1928,2073,1895,378,937,1858,1257,1593,537,1068,1416,1507,943,1640,1212,1545,1219,1559,394,2091,914,184,206,415,922,1615
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.6160723009781515,0.21377219628069816,0.3107081753546436,-0.31336929154874354,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.08028608865991266,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.12957783544472734,1.2084658865131082,-0.46621885306434724,-0.624229536412293,-0.4275222886859329,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.6452247828693638,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,-0.2021240853281833,0.11412915938872559,-0.12957783544472734,0.11412915938872559,-0.12957783544472734,0.8153380062854007,-0.624229536412293,0.3424442560190503,1.15845820052481,1.107748671810519,0.7875391296424109,0.3424442560190503,-0.16568914771639728
2,631
Ub specific processing proteases
18
66
3.313003
0.000923
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P45880,Q96FW1,Q13309,P49721,O94966,P49720,P21796,Q99436,Q14318,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,267,147,294,18,139,142,85,394,380,59,62
515,874,132,188,1843,787,825,1617,929,1149,139,1106,1850,1445,59,85,1011,749,349,350,973,62,34,106,1893,1115,267,1449,1066,142,18,1894,1537,2073,378,937,1858,1257,1593,1068,2506,1416,294,380,1364,1507,943,540,765,1212,1168,769,1084,1172,814,147,611,394,2091,2542,920,206,922,1237,735,1382
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.40508352216113896,0.3739010427175194,-0.2021240853281833,0.3107081753546436,0.14765384784078572,1.2822041225107923,0.1808662269600239,-0.3891484207838882,-0.058326639732175146,2.0274549169815406,1.5854529614565336,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.977767688006064,-0.058326639732175146,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.12957783544472734,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-1.538154279489105,-0.023187036139176026,0.9244343611620436,0.8153380062854007,0.011628382363652217,-0.09379028637419248,0.3107081753546436,0.6452247828693638,0.4359965476908903,0.11412915938872559,0.14765384784078572,0.4359965476908903,0.21377219628069816,0.14765384784078572,0.40508352216113896,1.2822041225107923,0.5866809767008758,0.8153380062854007,-0.624229536412293,-1.7765736441710231,0.3424442560190503,1.107748671810519,0.3424442560190503,0.11412915938872559,0.46664484400905687,0.011628382363652217
2,631
Scf skp2 mediated degradation of p27 p21
14
41
3.311798
0.000927
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,Q13309,P49721,P49720,Q99436,P20618,P11802,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,294,18,142,394,59,279,62
515,874,132,188,1843,825,929,279,1445,59,833,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,658,1068,1416,294,2361,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.9511996966722966,-0.058326639732175146,2.0274549169815406,0.3739010427175194,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.023187036139176026,0.9244343611620436,-1.085306619758222,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Cyclin a cdk2 associated events at s phase entry
14
42
3.309507
0.000935
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,Q13309,P49721,P49720,Q99436,P20618,P11802,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,294,18,142,394,59,279,62
515,874,132,188,1843,825,929,279,1445,59,833,1011,749,349,350,973,62,34,106,835,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,658,1068,1416,294,2361,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.9511996966722966,-0.058326639732175146,2.0274549169815406,0.3739010427175194,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,0.3739010427175194,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.023187036139176026,0.9244343611620436,-1.085306619758222,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Membrane lipid metabolic process
10
30
3.291273
0.000997
P50897,Q06136,Q99805,O60762,Q9H490,P30153,Q8NBX0,P06865,Q8NCC3,P04066
Processes and pathways
GO Biological process
msigdb_gobp
314,2,26,190,184,280,154,276,27,150
1711,1050,190,791,1848,150,880,276,310,2032,1399,563,280,314,2,1824,983,154,27,1219,2119,1559,1132,26,1181,184,1432,1478,1835,2434
-0.2759642918046235,0.21377219628069816,1.13319242501366,0.40508352216113896,-0.3891484207838882,1.257791335055367,0.3424442560190503,0.9511996966722966,0.8974686565746289,-0.5842434527420278,-0.023187036139176026,0.6160723009781515,0.9511996966722966,0.8974686565746289,5.1051968387484905,-0.3510973783434665,0.278687675691609,1.257791335055367,2.9358813459906243,0.11412915938872559,-0.6645376888850335,-0.12957783544472734,0.1808662269600239,3.0124937225901696,0.14765384784078572,1.15845820052481,-0.023187036139176026,-0.058326639732175146,-0.3510973783434665,-1.26260245787533
2,631
Degradation of axin
12
37
3.283895
0.001024
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,1507,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Cross presentation of soluble exogenous antigens endosomes
12
37
3.283895
0.001024
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,1507,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Stabilization of p53
12
39
3.283227
0.001026
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1106,1445,59,1011,749,349,350,973,62,34,106,1893,837,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,1507,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.1808662269600239,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.3739010427175194,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Regulation of pten stability and activity
12
40
3.274269
0.001059
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,835,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1208,1068,1416,1507,943,394,2091,206,820,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,0.3739010427175194,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.11412915938872559,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.40508352216113896,0.3424442560190503
2,631
Degradation of beta catenin by the destruction complex
15
46
3.273779
0.001061
P28072,O00233,Q13363,O00487,Q9UL46,P49841,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P30153,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,295,188,206,351,350,106,349,18,142,394,59,280,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,280,2138,1893,1115,1066,527,142,18,351,1894,2073,757,378,937,1858,1257,1593,658,1068,1416,295,2361,1506,1507,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,0.9511996966722966,-0.705167787937405,-0.4275222886859329,0.1808662269600239,0.21377219628069816,0.6452247828693638,1.2822041225107923,3.3458384043052356,0.8429236851350608,-0.4275222886859329,-0.624229536412293,0.4359965476908903,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.023187036139176026,0.9244343611620436,-1.085306619758222,-0.09379028637419248,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Proteasome
12
36
3.271001
0.001072
P28072,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q9Y244,Q99436,P20618,P28070
Processes and pathways
KEGG Pathways
msigdb_kegg
34,188,206,350,106,349,18,142,259,394,59,62
515,874,188,1843,825,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,1507,943,394,2091,206,922,259
0.6452247828693638,0.3424442560190503,1.13319242501366,-0.3891484207838882,0.3739010427175194,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503,1.0041412915640857
2,631
G1 s dna damage checkpoints
12
40
3.266362
0.001089
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1106,1445,59,833,1011,749,349,350,973,62,34,106,1893,837,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,1507,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.1808662269600239,-0.058326639732175146,2.0274549169815406,0.3739010427175194,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.3739010427175194,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Signaling by notch
16
56
3.262846
0.001103
P28072,O00233,Q15363,O00487,Q9UL46,P25789,Q9UBV2,P28074,P25788,P67809,P49721,P49720,Q99436,P20618,P28070,Q9H488
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,5,188,206,350,73,106,349,79,18,142,394,59,62,360
515,874,132,188,1843,825,929,1106,2199,1401,1445,59,1011,749,349,350,973,62,34,106,1893,1586,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1728,568,658,79,2494,759,1068,1416,2185,2361,943,5,2013,910,1129,394,2091,360,698,73,206,922,737
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.1808662269600239,-0.7873933421725157,-0.023187036139176026,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,-0.16568914771639728,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,-0.2759642918046235,0.6160723009781515,0.5271655315673739,1.6738834351964975,-1.4914291062743523,0.4359965476908903,0.21377219628069816,-0.023187036139176026,-0.7461197124067016,-1.085306619758222,0.3107081753546436,4.86328444949437,-0.544579561175527,0.3424442560190503,0.1808662269600239,0.8153380062854007,-0.624229536412293,0.8429236851350608,0.49703301170235065,1.781481931571495,1.107748671810519,0.3424442560190503,0.46664484400905687
2,631
Fceri mediated nf kb activation
13
43
3.259943
0.001114
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49427,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,107,18,142,394,59,62
515,874,132,188,1843,825,929,594,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,107,142,18,1894,2073,378,1304,937,1858,1257,1593,658,1068,1416,2361,1507,943,765,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.5866809767008758,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.47179933358734,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.04611947228614343,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.4359965476908903,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Amide binding
35
92
3.234117
0.00122
P42892,Q9UIQ6,Q15388,P00374,Q8WTV0,P40855,P45880,P26885,Q9H7Z7,P52294,Q96AY3,P21266,P55786,Q15392,P61619,P52292,Q03519,P41440,O43731,Q9NZ08,Q9BYT8,P62942,O00264,P45877,P07602,P61758,Q8TEX9,P28161,P21796,Q9Y3C6,Q9NXR7,O60684,Q92973,P10321,P24390
Functions
GO Molecular function
msigdb_gomf
245,4,540,9,10,373,267,16,551,159,31,523,33,36,533,420,293,49,54,55,325,60,556,313,310,446,481,336,85,229,363,94,100,347,123
1666,556,824,704,1047,789,875,54,94,1885,1149,9,793,1993,561,310,1717,1444,347,713,1850,523,85,1158,1533,123,16,1013,336,2039,1583,2002,1202,373,1724,49,245,313,267,976,893,1351,2586,2399,2008,420,159,2230,33,1775,533,446,60,1777,659,939,760,293,1070,2204,940,980,1266,2518,540,36,481,10,2280,100,31,1742,1035,774,1223,1132,2163,325,2604,1229,551,956,778,1137,363,55,1478,1480,959,4,1709,229
-0.23888251175943867,0.6160723009781515,0.3739010427175194,0.46664484400905687,0.21377219628069816,0.40508352216113896,0.3424442560190503,2.0864437380032115,1.5176885982704214,-0.4275222886859329,0.14765384784078572,4.004804150480747,0.40508352216113896,-0.544579561175527,0.6160723009781515,0.8974686565746289,-0.2759642918046235,-0.058326639732175146,0.8429236851350608,0.46664484400905687,-0.3891484207838882,0.6452247828693638,1.5854529614565336,0.14765384784078572,-0.12957783544472734,1.3544699048423925,3.548158845230379,0.24637748849157123,0.8702994873684097,-0.5842434527420278,-0.16568914771639728,-0.544579561175527,0.11412915938872559,0.8153380062854007,-0.2759642918046235,2.2016422601947694,1.0041412915640857,0.8974686565746289,0.977767688006064,0.278687675691609,0.3424442560190503,0.011628382363652217,-2.2258296179446355,-1.17331342279577,-0.544579561175527,0.759523653936807,1.2332126975583004,-0.8289885581393346,2.679467443709186,-0.31336929154874354,0.6452247828693638,0.7312880952006297,2.0274549169815406,-0.31336929154874354,0.5271655315673739,0.3107081753546436,0.4359965476908903,0.9244343611620436,0.21377219628069816,-0.7873933421725157,0.3107081753546436,0.278687675691609,0.08028608865991266,-1.5851991561112928,0.6452247828693638,2.5096531511230316,0.7028288840536002,3.9225804558905155,-0.9131432773169984,1.4948164960337653,2.7125106347921997,-0.2759642918046235,0.24637748849157123,0.4359965476908903,0.11412915938872559,0.1808662269600239,-0.705167787937405,0.8974686565746289,-2.593080790101666,0.11412915938872559,0.6452247828693638,0.3107081753546436,0.4359965476908903,0.1808662269600239,0.8429236851350608,2.0864437380032115,-0.058326639732175146,-0.058326639732175146,0.3107081753546436,4.954689535317153,-0.23888251175943867,1.0563168307418604
2,631
Regulation of runx3 expression and activity
12
37
3.221337
0.001276
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,1893,837,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.3739010427175194,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Peptidase activity
29
100
3.21883
0.001287
P42892,Q9UIQ6,P42785,Q92905,Q96FW1,P02786,P49721,O94966,P49720,P55786,P28072,P50579,Q9NZ08,Q9H8M7,Q9BYT8,P20618,Q9H3G5,P28070,Q5JRX3,O00487,P16870,Q9HB40,P52888,P25789,P28074,Q01804,P36551,Q99436,P60900
Functions
GO Molecular function
msigdb_gomf
245,4,7,269,147,264,18,139,142,33,34,174,55,326,325,59,196,62,66,188,208,93,97,350,106,353,233,394,378
588,188,1047,740,1050,1489,706,1335,708,1886,139,264,1889,493,1921,882,1850,208,59,831,350,62,34,106,2396,1346,2353,233,1499,1255,7,245,1449,599,142,18,174,1894,97,2230,1354,1537,33,378,2528,2494,842,353,687,1022,761,1504,1364,1638,1213,1825,809,66,1735,2016,1550,689,504,1869,1168,505,1170,910,1031,1084,269,1172,814,429,147,773,611,860,2057,394,1911,1279,409,817,863,325,196,550,2241,326,93,699,1234,1186,1092,55,4,1140,2219,1615
0.5866809767008758,1.13319242501366,0.21377219628069816,0.4359965476908903,0.21377219628069816,-0.09379028637419248,0.46664484400905687,0.011628382363652217,0.46664484400905687,-0.4275222886859329,1.2822041225107923,0.977767688006064,-0.4275222886859329,0.6741423628769925,-0.46621885306434724,0.3424442560190503,-0.3891484207838882,1.0821243548255537,2.0274549169815406,0.3739010427175194,0.8429236851350608,2.007578507508111,2.561425042425346,1.47179933358734,-1.17331342279577,0.011628382363652217,-1.085306619758222,1.0303233973076291,-0.09379028637419248,0.08028608865991266,4.1079376469458575,1.0041412915640857,-0.058326639732175146,0.5866809767008758,1.2822041225107923,3.3458384043052356,1.183548528852841,-0.4275222886859329,1.4948164960337653,-0.8289885581393346,0.011628382363652217,-0.12957783544472734,2.679467443709186,0.8153380062854007,-1.6802476075658623,-1.4914291062743523,0.3739010427175194,0.8429236851350608,0.49703301170235065,0.24637748849157123,0.4359965476908903,-0.09379028637419248,0.011628382363652217,-0.2021240853281833,0.11412915938872559,-0.3510973783434665,0.40508352216113896,1.865329260145266,-0.2759642918046235,-0.544579561175527,-0.12957783544472734,0.49703301170235065,0.6741423628769925,-0.3891484207838882,0.14765384784078572,0.6741423628769925,0.14765384784078572,0.3424442560190503,0.24637748849157123,0.21377219628069816,0.977767688006064,0.14765384784078572,0.40508352216113896,0.759523653936807,1.2822041225107923,0.4359965476908903,0.5866809767008758,0.3739010427175194,-0.5842434527420278,0.8153380062854007,-0.4275222886859329,0.08028608865991266,0.7875391296424109,0.40508352216113896,0.3739010427175194,0.8974686565746289,1.13319242501366,0.6452247828693638,-0.8289885581393346,0.8974686565746289,1.5404174998791007,0.49703301170235065,0.11412915938872559,0.14765384784078572,0.21377219628069816,2.0864437380032115,4.954689535317153,0.1808662269600239,-0.7873933421725157,-0.16568914771639728
2,631
Clec7a dectin 1 signaling
14
47
3.216315
0.001298
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49427,P49721,P49720,Q99436,O43865,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,107,18,142,394,177,59,62
515,874,132,188,1843,825,177,929,594,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,107,142,18,1894,2073,378,531,1304,937,1858,1257,1593,658,1068,1070,1416,2361,1507,943,765,1739,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,1.15845820052481,0.3107081753546436,0.5866809767008758,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.47179933358734,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.6452247828693638,0.04611947228614343,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,0.21377219628069816,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.4359965476908903,-0.2759642918046235,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Skin nodule
7
17
3.193721
0.001405
Q92990,O75874,P35637,P52732,P48735,Q15437,Q9NZ08
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
137,41,266,235,17,22,55
41,880,279,1401,1671,2138,266,17,893,235,1120,1307,1824,22,137,1378,55
2.4038695750039927,0.3424442560190503,0.9511996966722966,-0.023187036139176026,-0.23888251175943867,-0.705167787937405,0.977767688006064,3.521809624851483,0.3424442560190503,1.0303233973076291,0.1808662269600239,0.04611947228614343,-0.3510973783434665,3.1756606722953644,1.3064533352461962,0.011628382363652217,2.0864437380032115
2,631
Hedgehog ligand biogenesis
13
41
3.184756
0.001449
P28072,O00233,O00487,Q9UL46,P25789,P28074,Q9UBV2,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,73,349,18,142,394,59,62
515,874,132,188,1843,825,929,1995,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,1895,378,937,1858,1257,1593,2494,1068,1416,1507,943,394,2091,73,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.544579561175527,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,-0.4275222886859329,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,-1.4914291062743523,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.781481931571495,1.107748671810519,0.3424442560190503
2,631
Proteasome complex
14
50
3.178107
0.001482
P54725,P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P60900,P28070
Localization
GO Cellular component
msigdb_gocc
166,34,132,188,206,350,106,349,18,142,394,59,378,62
515,874,132,188,1843,825,558,929,1761,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,1537,166,1928,2073,1895,378,937,1858,1257,1593,537,1068,1416,1507,943,1640,1212,1545,394,2091,914,206,415,922,1615
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.6160723009781515,0.3107081753546436,-0.31336929154874354,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.12957783544472734,1.2084658865131082,-0.46621885306434724,-0.624229536412293,-0.4275222886859329,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.6452247828693638,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,-0.2021240853281833,0.11412915938872559,-0.12957783544472734,0.8153380062854007,-0.624229536412293,0.3424442560190503,1.107748671810519,0.7875391296424109,0.3424442560190503,-0.16568914771639728
2,631
Cellular response to hypoxia
12
41
3.162013
0.001567
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,604,1507,943,1639,850,394,2091,640,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,0.5866809767008758,-0.09379028637419248,0.3107081753546436,-0.2021240853281833,0.3739010427175194,0.8153380062854007,-0.624229536412293,0.5570467687489573,1.107748671810519,0.3424442560190503
2,631
Endopeptidase activity
15
52
3.161336
0.00157
P52888,P42892,P28072,Q5JRX3,P25789,P28074,Q92905,P49721,P49720,Q9NZ08,Q99436,Q9BYT8,P20618,P60900,P28070
Functions
GO Molecular function
msigdb_gomf
97,245,34,66,350,106,269,18,142,55,394,325,59,378,62
1047,1050,1489,706,1335,882,1850,59,831,350,62,34,106,1346,2353,1499,1255,245,1449,599,142,18,97,1354,1537,378,2528,2494,687,761,1504,1364,1213,1825,66,1735,1168,1170,910,269,1172,814,611,2057,394,1279,409,817,325,55,1140,2219
0.21377219628069816,0.21377219628069816,-0.09379028637419248,0.46664484400905687,0.011628382363652217,0.3424442560190503,-0.3891484207838882,2.0274549169815406,0.3739010427175194,0.8429236851350608,2.007578507508111,2.561425042425346,1.47179933358734,0.011628382363652217,-1.085306619758222,-0.09379028637419248,0.08028608865991266,1.0041412915640857,-0.058326639732175146,0.5866809767008758,1.2822041225107923,3.3458384043052356,1.4948164960337653,0.011628382363652217,-0.12957783544472734,0.8153380062854007,-1.6802476075658623,-1.4914291062743523,0.49703301170235065,0.4359965476908903,-0.09379028637419248,0.011628382363652217,0.11412915938872559,-0.3510973783434665,1.865329260145266,-0.2759642918046235,0.14765384784078572,0.14765384784078572,0.3424442560190503,0.977767688006064,0.14765384784078572,0.40508352216113896,0.5866809767008758,-0.5842434527420278,0.8153380062854007,0.08028608865991266,0.7875391296424109,0.40508352216113896,0.8974686565746289,2.0864437380032115,0.1808662269600239,-0.7873933421725157
2,631
Switching of origins to a post replicative state
16
56
3.156804
0.001595
P28072,O00233,Q9UJX6,O00487,Q9UL46,P25789,P28074,P25788,Q9UJX3,Q13309,Q9Y619,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,273,188,206,350,106,349,126,294,47,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,833,1813,1011,749,349,350,973,62,34,106,1200,1673,1201,1347,1893,1115,1066,142,18,1589,1894,2073,378,937,1858,1257,1593,658,1068,1416,294,2361,1903,1507,943,1544,815,394,2091,731,2555,126,674,273,206,922,47
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.3739010427175194,-0.3510973783434665,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,0.11412915938872559,-0.23888251175943867,0.11412915938872559,0.011628382363652217,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.16568914771639728,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.023187036139176026,0.9244343611620436,-1.085306619758222,-0.4275222886859329,-0.09379028637419248,0.3107081753546436,-0.12957783544472734,0.40508352216113896,0.8153380062854007,-0.624229536412293,0.46664484400905687,-1.9234564142985089,1.3544699048423925,0.5271655315673739,0.977767688006064,1.107748671810519,0.3424442560190503,2.2204944858377984
2,631
Metabolism of polyamines
15
39
3.155514
0.001602
P19623,P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,O00231,P20618,P60900,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
522,34,132,188,206,350,106,349,18,142,394,515,59,378,62
515,874,132,188,1843,825,929,1445,522,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,529,2073,378,937,1858,1257,1593,1068,1416,1507,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,0.6452247828693638,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,0.6452247828693638,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Regulation of ras by gaps
12
39
3.142994
0.001672
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,652,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,2112,1507,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.5271655315673739,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.6645376888850335,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Runx1 regulates transcription of genes involved in differentiation of hscs
12
40
3.141356
0.001682
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,2199,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1728,759,1068,1416,1507,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.7873933421725157,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,-0.2759642918046235,0.4359965476908903,0.21377219628069816,-0.023187036139176026,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Golgi associated vesicle
13
25
3.139341
0.001693
Q15363,Q9BVK6,Q8WVM8,P49755,Q9UBF2,Q9Y3B3,O43731,P51153,Q8N511,P24390,Q9Y678,Q9HD26,P11717
Localization
GO Cellular component
msigdb_gocc
5,102,343,143,555,53,54,498,121,123,230,459,494
1846,54,1756,1444,494,123,1254,1500,143,498,1205,2141,532,797,1930,1120,5,121,343,102,459,672,555,53,230
-0.3891484207838882,2.0864437380032115,-0.31336929154874354,-0.058326639732175146,0.6741423628769925,1.3544699048423925,0.08028608865991266,-0.09379028637419248,1.2822041225107923,0.6741423628769925,0.11412915938872559,-0.705167787937405,0.6452247828693638,0.40508352216113896,-0.46621885306434724,0.1808662269600239,4.86328444949437,1.3782415831495038,0.8702994873684097,1.4948164960337653,0.7312880952006297,0.5271655315673739,0.6452247828693638,2.1058970915870394,1.0563168307418604
2,631
vesicle coat protein
6
24
3.131674
0.001738
Q15363,Q9BVK6,P49755,Q9Y3B3,Q15437,Q15436
Functions
Panther Protein class
panther_protein_class
5,102,143,53,22,61
1244,2101,1444,1254,1500,143,896,1205,2141,1408,1678,797,1930,980,5,61,22,1426,102,555,462,416,53,230
0.08028608865991266,-0.6645376888850335,-0.058326639732175146,0.08028608865991266,-0.09379028637419248,1.2822041225107923,0.3424442560190503,0.11412915938872559,-0.705167787937405,-0.023187036139176026,-0.23888251175943867,0.40508352216113896,-0.46621885306434724,0.278687675691609,4.86328444949437,2.0274549169815406,3.1756606722953644,-0.023187036139176026,1.4948164960337653,0.6452247828693638,0.7312880952006297,0.7875391296424109,2.1058970915870394,1.0563168307418604
2,631
Response to toxic substance
20
44
3.117318
0.001825
P35754,P30041,P00374,P07099,P35670,O60341,P21266,P30048,Q7Z5K2,O95831,Q16881,Q8TC12,Q8WVM8,Q6DKJ4,P28161,P11766,P78417,Q16611,P36551,P08183
Processes and pathways
GO Biological process
msigdb_gobp
497,370,9,25,398,517,523,525,425,46,575,451,343,341,336,596,236,112,233,622
2063,1883,1050,644,517,46,9,930,1398,1993,1107,25,622,1056,1532,596,747,523,1199,336,370,1581,525,890,398,497,233,2108,236,1969,762,1504,112,575,341,425,451,1978,343,1911,1132,1318,1744,1753
-0.624229536412293,-0.4275222886859329,0.21377219628069816,0.5271655315673739,0.6452247828693638,2.239250199852926,4.004804150480747,0.3107081753546436,-0.023187036139176026,-0.544579561175527,0.1808662269600239,3.0124937225901696,0.5570467687489573,0.21377219628069816,-0.12957783544472734,0.5866809767008758,0.4359965476908903,0.6452247828693638,0.11412915938872559,0.8702994873684097,0.8153380062854007,-0.16568914771639728,0.6452247828693638,0.3424442560190503,0.7875391296424109,0.6741423628769925,1.0303233973076291,-0.6645376888850335,1.0303233973076291,-0.5052379861113006,0.4359965476908903,-0.09379028637419248,1.4253222050252763,0.6160723009781515,0.8702994873684097,0.759523653936807,0.7312880952006297,-0.5052379861113006,0.8702994873684097,-0.4275222886859329,0.1808662269600239,0.04611947228614343,-0.2759642918046235,-0.2759642918046235
2,631
Degradation of gli1 by the proteasome
12
40
3.092562
0.001984
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1197,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,658,1068,1416,2361,1507,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.11412915938872559,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Interleukin 1 signaling
12
43
3.0862
0.002027
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,2033,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,1304,937,1858,1257,1593,658,1261,1068,1416,2361,1507,943,765,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.5842434527420278,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.04611947228614343,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.08028608865991266,0.21377219628069816,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.4359965476908903,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Copi coated vesicle
6
13
3.082473
0.002053
Q15363,P49755,Q9Y3B3,O43731,Q8N511,P24390
Localization
GO Cellular component
msigdb_gocc
5,143,53,54,121,123
54,123,1254,1500,143,1205,2141,797,5,121,555,53,230
2.0864437380032115,1.3544699048423925,0.08028608865991266,-0.09379028637419248,1.2822041225107923,0.11412915938872559,-0.705167787937405,0.40508352216113896,4.86328444949437,1.3782415831495038,0.6452247828693638,2.1058970915870394,1.0563168307418604
2,631
Proteasome core complex
9
14
3.072584
0.002122
P28072,P25789,P25788,P28074,P49721,P49720,Q99436,P20618,P28070
Localization
GO Cellular component
msigdb_gocc
34,350,349,106,18,142,394,59,62
1843,59,1011,749,349,350,973,62,34,106,142,18,378,394
-0.3891484207838882,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,1.2822041225107923,3.3458384043052356,0.8153380062854007,0.8153380062854007
2,631
Proteasome, subunit alpha/beta [IPR001353]
9
14
3.072584
0.002122
P28072,P25789,P25788,P28074,P49721,P49720,Q99436,P20618,P28070
Sequence
InterPro Family
interpro_family
34,350,349,106,18,142,394,59,62
1843,59,1011,749,349,350,973,62,34,106,142,18,378,394
-0.3891484207838882,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,1.2822041225107923,3.3458384043052356,0.8153380062854007,0.8153380062854007
2,631
Deubiquitination
21
79
3.065948
0.00217
O00233,P45880,Q8NB78,Q96FW1,P49721,O94966,P49720,P54725,P28072,Q13309,P20618,P28070,O00487,Q9UL46,P21796,Q9NXR7,P25789,P28074,P25788,Q99436,Q14318
Processes and pathways
Reactome Pathways
msigdb_reactome
132,267,13,147,18,139,142,166,34,294,59,62,188,206,85,363,350,106,349,394,380
515,874,132,188,1843,787,490,825,1617,929,1149,139,1105,1106,1107,1850,1445,59,85,2106,1011,749,349,350,973,62,34,106,1893,1115,267,1449,1066,142,18,2175,1894,1537,166,1928,2073,1895,378,937,1858,1257,1593,1068,2506,1416,294,2480,380,1364,1507,943,540,765,1212,690,1168,769,13,1084,1172,814,147,611,394,2091,2542,363,920,206,922,1237,735,1382,1615
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.40508352216113896,0.6741423628769925,0.3739010427175194,-0.2021240853281833,0.3107081753546436,0.14765384784078572,1.2822041225107923,0.1808662269600239,0.1808662269600239,0.1808662269600239,-0.3891484207838882,-0.058326639732175146,2.0274549169815406,1.5854529614565336,-0.6645376888850335,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.977767688006064,-0.058326639732175146,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.7461197124067016,-0.4275222886859329,-0.12957783544472734,1.2084658865131082,-0.46621885306434724,-0.624229536412293,-0.4275222886859329,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-1.538154279489105,-0.023187036139176026,0.9244343611620436,-1.445023740434061,0.8153380062854007,0.011628382363652217,-0.09379028637419248,0.3107081753546436,0.6452247828693638,0.4359965476908903,0.11412915938872559,0.49703301170235065,0.14765384784078572,0.4359965476908903,3.5873366483495683,0.21377219628069816,0.14765384784078572,0.40508352216113896,1.2822041225107923,0.5866809767008758,0.8153380062854007,-0.624229536412293,-1.7765736441710231,0.8429236851350608,0.3424442560190503,1.107748671810519,0.3424442560190503,0.11412915938872559,0.46664484400905687,0.011628382363652217,-0.16568914771639728
2,631
Interleukin 1 family signaling
12
45
3.061439
0.002203
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,2033,1445,59,1011,749,349,350,973,62,34,106,1893,1625,1115,1066,142,18,1894,2073,378,1304,937,1858,1257,1593,658,1261,1307,1068,1416,2361,1507,943,765,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.5842434527420278,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,-0.2021240853281833,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.04611947228614343,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.08028608865991266,0.04611947228614343,0.21377219628069816,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.4359965476908903,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
C type lectin receptors clrs
14
51
3.046036
0.002319
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49427,P49721,P49720,Q99436,O43865,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,107,18,142,394,177,59,62
515,874,132,188,1843,825,177,929,594,1197,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,107,142,18,1894,2073,378,531,1304,937,1858,1257,1593,658,1068,1070,2050,1635,1416,2361,1507,943,765,806,1739,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,1.15845820052481,0.3107081753546436,0.5866809767008758,0.11412915938872559,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.47179933358734,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.6452247828693638,0.04611947228614343,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,0.21377219628069816,-0.5842434527420278,-0.2021240853281833,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.4359965476908903,0.40508352216113896,-0.2759642918046235,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Proteasome degradation
12
41
3.033045
0.002421
P28072,O00233,Q9UL46,P25789,P28074,P25788,P10321,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
WikiPathways
msigdb_wp
34,132,206,350,106,349,347,18,142,394,59,62
515,874,132,1843,825,929,793,1716,1442,347,2199,1445,59,2170,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.40508352216113896,-0.2759642918046235,-0.058326639732175146,0.8429236851350608,-0.7873933421725157,-0.058326639732175146,2.0274549169815406,-0.7461197124067016,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Peptide binding
26
61
3.02611
0.002477
P42892,Q9UIQ6,Q15388,Q8WTV0,P40855,Q9H7Z7,P52294,P55786,P21266,Q15392,P52292,P61619,Q03519,O43731,Q9NZ08,Q9BYT8,P45877,P61758,Q8TEX9,P28161,Q9Y3C6,Q9NXR7,O60684,Q92973,P10321,P24390
Functions
GO Molecular function
msigdb_gomf
245,4,540,10,373,551,159,33,523,36,420,533,293,54,55,325,313,446,481,336,229,363,94,100,347,123
556,824,1047,789,875,54,94,1149,793,1717,1444,347,1850,523,1533,123,1013,336,2039,2002,1202,373,245,313,976,2586,2399,420,159,2230,33,1775,533,446,1777,293,1070,2204,980,1266,2518,540,36,481,10,100,1742,774,1132,2163,325,2604,551,778,1137,363,55,1480,959,4,229
0.6160723009781515,0.3739010427175194,0.21377219628069816,0.40508352216113896,0.3424442560190503,2.0864437380032115,1.5176885982704214,0.14765384784078572,0.40508352216113896,-0.2759642918046235,-0.058326639732175146,0.8429236851350608,-0.3891484207838882,0.6452247828693638,-0.12957783544472734,1.3544699048423925,0.24637748849157123,0.8702994873684097,-0.5842434527420278,-0.544579561175527,0.11412915938872559,0.8153380062854007,1.0041412915640857,0.8974686565746289,0.278687675691609,-2.2258296179446355,-1.17331342279577,0.759523653936807,1.2332126975583004,-0.8289885581393346,2.679467443709186,-0.31336929154874354,0.6452247828693638,0.7312880952006297,-0.31336929154874354,0.9244343611620436,0.21377219628069816,-0.7873933421725157,0.278687675691609,0.08028608865991266,-1.5851991561112928,0.6452247828693638,2.5096531511230316,0.7028288840536002,3.9225804558905155,1.4948164960337653,-0.2759642918046235,0.4359965476908903,0.1808662269600239,-0.705167787937405,0.8974686565746289,-2.593080790101666,0.6452247828693638,0.4359965476908903,0.1808662269600239,0.8429236851350608,2.0864437380032115,-0.058326639732175146,0.3107081753546436,4.954689535317153,1.0563168307418604
2,631
Fc epsilon receptor fceri signaling
15
53
3.024822
0.002488
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49427,P49721,P49720,P62993,Q99436,O43865,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,107,18,142,210,394,177,59,62
515,874,132,188,1843,825,177,929,594,1445,885,59,1011,749,349,350,419,973,62,34,106,1721,1893,1115,1066,107,142,18,1894,2073,378,1304,937,1858,1257,1593,210,2109,658,1068,1070,2050,1635,1416,2361,1507,943,765,806,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,1.15845820052481,0.3107081753546436,0.5866809767008758,-0.058326639732175146,0.3424442560190503,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.759523653936807,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.2759642918046235,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.47179933358734,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.04611947228614343,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,1.0821243548255537,-0.6645376888850335,0.5271655315673739,0.21377219628069816,0.21377219628069816,-0.5842434527420278,-0.2021240853281833,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.4359965476908903,0.40508352216113896,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
protease
12
42
3.0222
0.002509
P28072,O00233,Q99436,P25789,P28074,P25788,P50579,P49721,P49720,P16870,P20618,P28070
Functions
Panther Protein class
panther_protein_class
34,132,394,350,106,349,174,18,142,208,59,62
874,132,1843,825,708,1886,208,1445,59,1011,749,349,350,973,62,34,106,1893,1255,1115,1066,142,18,174,2073,378,1858,1257,1593,2494,1416,1638,1550,394,2091,863,916,2241,1186,922,1285,1949
0.3424442560190503,1.3064533352461962,-0.3891484207838882,0.3739010427175194,0.46664484400905687,-0.4275222886859329,1.0821243548255537,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.08028608865991266,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,1.183548528852841,-0.624229536412293,0.8153380062854007,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,-1.4914291062743523,-0.023187036139176026,-0.2021240853281833,-0.12957783544472734,0.8153380062854007,-0.624229536412293,0.3739010427175194,0.3424442560190503,-0.8289885581393346,0.14765384784078572,0.3424442560190503,0.08028608865991266,-0.46621885306434724
2,631
Corneal opacity
17
42
3.015647
0.002564
Q06136,O43505,Q13363,P53701,O95163,O43684,Q03001,P40855,Q15813,Q15645,P52732,O96028,O75845,Q9H3P2,Q9UBM7,P35670,P04066
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
2,35,295,268,440,308,474,373,502,384,235,140,332,287,23,398,150
1190,35,308,2348,1952,1335,332,440,2132,140,1847,1848,150,880,1763,493,1399,683,2269,1348,398,373,935,235,268,1118,1964,1120,474,2,295,1824,725,384,502,946,2317,287,994,23,2448,1327
0.11412915938872559,2.5269915348506964,0.8974686565746289,-1.085306619758222,-0.5052379861113006,0.011628382363652217,0.8702994873684097,0.7312880952006297,-0.705167787937405,1.2822041225107923,-0.3891484207838882,-0.3891484207838882,1.257791335055367,0.3424442560190503,-0.31336929154874354,0.6741423628769925,-0.023187036139176026,0.49703301170235065,-0.9131432773169984,0.011628382363652217,0.7875391296424109,0.8153380062854007,0.3107081753546436,1.0303233973076291,0.977767688006064,0.1808662269600239,-0.5052379861113006,0.1808662269600239,0.7028288840536002,5.1051968387484905,0.9244343611620436,-0.3510973783434665,0.46664484400905687,0.8153380062854007,0.6741423628769925,0.3107081753546436,-0.9985829370388538,0.9511996966722966,0.278687675691609,3.102383344071522,-1.307727538673511,0.04611947228614343
2,631
Nucleophile aminohydrolases, N-terminal [IPR029055]
10
18
3.014122
0.002577
P28072,P25789,P25788,P28074,P49721,P49720,Q99436,P20618,P60900,P28070
Sequence
InterPro Superfamily
interpro_homologous_superfamily
34,350,349,106,18,142,394,59,378,62
1843,1293,59,1011,749,349,350,973,62,34,106,142,18,378,447,723,1550,394
-0.3891484207838882,0.04611947228614343,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,1.2822041225107923,3.3458384043052356,0.8153380062854007,0.7312880952006297,0.46664484400905687,-0.12957783544472734,0.8153380062854007
2,631
Subcutaneous nodule
6
15
3.006167
0.002646
O75874,P35637,P52732,P48735,Q15437,Q9NZ08
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
41,266,235,17,22,55
41,880,279,1671,2138,266,17,893,235,1120,1307,1824,22,1378,55
2.4038695750039927,0.3424442560190503,0.9511996966722966,-0.23888251175943867,-0.705167787937405,0.977767688006064,3.521809624851483,0.3424442560190503,1.0303233973076291,0.1808662269600239,0.04611947228614343,-0.3510973783434665,3.1756606722953644,0.011628382363652217,2.0864437380032115
2,631
Transcriptional regulation by runx3
12
41
3.005462
0.002652
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1106,1445,59,2001,1011,749,349,350,973,62,34,106,2138,1893,837,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,2185,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.1808662269600239,-0.058326639732175146,2.0274549169815406,-0.544579561175527,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.705167787937405,-0.4275222886859329,0.3739010427175194,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.7461197124067016,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Transport vesicle membrane
12
38
3.000749
0.002693
Q15363,Q86Y82,P10321,O00429,P49755,P49257,Q9Y6B6,Q9Y3B3,Q15437,P16870,P0DP25,Q15436
Localization
GO Cellular component
msigdb_gocc
5,299,347,108,143,234,82,53,22,208,151,61
108,788,2329,1756,1004,1333,1803,2566,1758,1714,1244,2101,793,1444,151,347,208,1402,2037,234,143,1117,1819,1678,719,500,1930,1784,5,61,22,1788,299,412,1380,53,82,1045
1.4486352146024881,0.40508352216113896,-1.041784332284214,-0.31336929154874354,0.24637748849157123,0.011628382363652217,-0.3510973783434665,-2.022972918699234,-0.31336929154874354,-0.2759642918046235,0.08028608865991266,-0.6645376888850335,0.40508352216113896,-0.058326639732175146,1.257791335055367,0.8429236851350608,1.0821243548255537,-0.023187036139176026,-0.5842434527420278,1.0303233973076291,1.2822041225107923,0.1808662269600239,-0.3510973783434665,-0.23888251175943867,0.46664484400905687,0.6741423628769925,-0.46621885306434724,-0.31336929154874354,4.86328444949437,2.0274549169815406,3.1756606722953644,-0.31336929154874354,0.9244343611620436,0.7875391296424109,0.011628382363652217,2.1058970915870394,1.6299370577151888,0.24637748849157123
2,631
Dectin 1 mediated noncanonical nf kb signaling
12
41
2.98947
0.002795
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,531,937,1858,1257,1593,658,1068,1416,2361,1507,943,1739,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.6452247828693638,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,-0.2759642918046235,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Tnfr2 non canonical nf kb pathway
12
41
2.98947
0.002795
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,531,937,1858,1257,1593,658,1068,1416,2361,1507,943,1739,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.6452247828693638,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,-0.2759642918046235,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Transcriptional regulation by runx2
16
51
2.98923
0.002797
P28072,O00233,O00487,Q9UL46,P49841,P25789,P28074,P25788,Q13309,P49721,P49720,Q99436,P20618,P60900,P11802,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,351,350,106,349,294,18,142,394,59,378,279,62
515,874,132,188,1843,825,929,1107,2524,279,1342,1445,59,1011,749,349,350,419,973,62,34,106,1721,835,1893,1586,1115,1066,142,18,351,1894,2073,378,937,1858,1257,1593,658,1068,1416,294,2361,1507,943,1221,394,2091,206,820,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.1808662269600239,-1.6325636329473232,0.9511996966722966,0.011628382363652217,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.759523653936807,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.2759642918046235,0.3739010427175194,-0.4275222886859329,-0.16568914771639728,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,0.8429236851350608,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.023187036139176026,0.9244343611620436,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.11412915938872559,0.8153380062854007,-0.624229536412293,1.107748671810519,0.40508352216113896,0.3424442560190503
2,631
Transport vesicle
27
79
2.978641
0.002895
Q15363,P11717,Q92905,P49755,Q9NR31,Q9UBF2,Q15437,P0DP25,P61421,Q86Y82,Q9Y3B3,O43731,Q9HD26,Q15436,P50897,O00461,Q9Y6B6,O15498,P16870,Q9Y678,Q9BVK6,P10321,O00429,P49257,P51153,P62820,P24390
Localization
GO Cellular component
msigdb_gocc
5,494,269,143,412,555,22,151,167,299,53,54,459,61,314,187,82,328,208,230,102,347,108,234,498,500,123
108,187,1048,788,2329,1145,328,1846,54,1756,1004,1333,1713,1803,2566,1758,1714,1244,1150,2101,793,1444,151,347,1009,494,208,1402,2037,123,750,1892,1254,597,1500,234,143,314,1117,498,2274,1819,1205,2141,1678,719,1896,532,167,797,500,1930,2049,1784,980,1865,5,61,22,1788,299,910,1426,269,1220,863,102,613,459,412,555,1380,2489,783,821,53,230,82,1045
1.4486352146024881,1.13319242501366,0.21377219628069816,0.40508352216113896,-1.041784332284214,0.14765384784078572,0.8702994873684097,-0.3891484207838882,2.0864437380032115,-0.31336929154874354,0.24637748849157123,0.011628382363652217,-0.2759642918046235,-0.3510973783434665,-2.022972918699234,-0.31336929154874354,-0.2759642918046235,0.08028608865991266,0.14765384784078572,-0.6645376888850335,0.40508352216113896,-0.058326639732175146,1.257791335055367,0.8429236851350608,0.24637748849157123,0.6741423628769925,1.0821243548255537,-0.023187036139176026,-0.5842434527420278,1.3544699048423925,0.4359965476908903,-0.4275222886859329,0.08028608865991266,0.5866809767008758,-0.09379028637419248,1.0303233973076291,1.2822041225107923,0.8974686565746289,0.1808662269600239,0.6741423628769925,-0.9131432773169984,-0.3510973783434665,0.11412915938872559,-0.705167787937405,-0.23888251175943867,0.46664484400905687,-0.4275222886859329,0.6452247828693638,1.2084658865131082,0.40508352216113896,0.6741423628769925,-0.46621885306434724,-0.5842434527420278,-0.31336929154874354,0.278687675691609,-0.3891484207838882,4.86328444949437,2.0274549169815406,3.1756606722953644,-0.31336929154874354,0.9244343611620436,0.3424442560190503,-0.023187036139176026,0.977767688006064,0.11412915938872559,0.3739010427175194,1.4948164960337653,0.5866809767008758,0.7312880952006297,0.7875391296424109,0.6452247828693638,0.011628382363652217,-1.445023740434061,0.4359965476908903,0.40508352216113896,2.1058970915870394,1.0563168307418604,1.6299370577151888,0.24637748849157123
2,631
Small molecule metabolic process
131
415
2.96553
0.003022
P35754,Q06136,P48449,P00374,Q8WTV0,Q9H9P8,P48735,Q9H7Z7,Q9NZJ6,Q04760,Q9UBM7,P62136,P07099,P28288,Q8NCC3,O60341,Q9NUJ1,Q15392,Q8N4Q0,P49902,P52788,O75874,P43034,Q9BQE5,Q9H773,Q16836,Q9Y619,P41440,Q9H2U2,P30837,Q13126,Q9BQG2,O15228,P05165,P52758,P54619,Q9UBX3,P21796,Q9Y3Z3,Q9Y5P6,Q9HB40,O00764,P00403,Q969T7,P11766,P61457,P38606,Q9BW91,P34949,P05091,P14174,Q9BY49,Q9H2D1,Q9NRN7,P23786,Q9BWD1,P15531,Q9UMR5,Q9BZX2,P31350,P06576,P04066,O14936,O43708,O00767,P51649,Q9P2T1,P17858,Q99707,O60725,P36404,Q9UJ83,Q9BTY2,Q9NVE7,P00492,P17812,O43865,P53602,Q10713,O60762,Q16850,Q14353,Q9UKK9,Q9UNI6,O75964,Q9Y285,Q9Y6N1,Q06210,P78330,Q9BRR6,P35914,P11908,P78417,Q15067,Q96K12,P46926,P09972,Q8N2K0,Q9BY32,Q9BYT8,P50897,O75845,P28161,O60678,Q9H488,P49841,P23368,Q14534,Q15120,Q96PU8,P62140,P34897,P00491,P09417,P43490,Q13572,Q9NRF8,Q92506,Q9H0R6,Q8TC12,P50416,P08754,Q06203,Q96SU4,Q6PJG6,P30085,Q8IYS1,Q96G03,O14734,O43598,O15294
Processes and pathways
GO Biological process
msigdb_gobp
497,2,8,9,10,552,17,551,554,536,23,534,25,524,27,517,32,36,37,528,529,41,526,44,45,574,47,49,583,56,57,64,557,561,566,567,84,85,87,91,93,589,595,101,596,600,597,638,120,621,625,129,130,131,627,668,649,156,155,152,647,150,149,644,642,655,171,651,169,172,173,703,176,186,681,178,177,686,687,190,202,201,733,734,198,736,738,723,721,225,223,221,236,248,270,281,277,300,324,325,314,332,336,330,360,351,348,381,383,392,379,371,368,369,374,405,434,426,458,451,444,441,447,483,479,467,505,506,489,491,490
2246,1239,1527,1666,2131,1385,704,589,642,489,2063,149,1191,2165,557,1711,490,2393,1570,1102,2601,491,644,1051,1571,2267,177,1389,1052,517,1990,330,1618,172,190,1439,1885,1005,1241,1573,1335,332,41,1195,198,878,2247,969,1396,1336,791,1715,1440,1887,1441,1667,9,1492,595,368,681,1760,1954,792,2426,1848,150,1397,1291,1245,1054,2102,1106,1993,621,561,647,2224,1153,25,1292,746,2268,1493,971,1293,1762,441,369,1056,1996,2287,1889,277,1248,2375,1532,1108,1057,1956,2626,1339,1623,713,1849,596,221,1010,1921,1154,1341,625,883,747,1922,1577,2198,649,2559,1399,830,1343,1344,178,651,1810,1718,1446,85,1671,1297,1157,1923,1158,1159,1345,348,1999,1494,1719,627,886,832,887,2352,1199,2201,1579,2251,1113,1720,336,524,1721,1015,467,2227,1768,1252,56,1817,1498,152,835,2137,1405,1769,836,1298,1299,371,120,2339,1583,497,223,173,1060,2619,1818,1771,1853,2041,597,1625,1674,1854,1724,1160,1585,49,932,1534,1773,526,1349,374,2005,281,1588,1725,1203,8,891,1065,976,17,1774,893,1627,1256,894,1351,2399,351,528,1628,795,1535,444,2008,314,934,935,655,1676,1353,566,529,1590,1629,686,1020,2072,567,1856,1118,1895,1679,2400,1206,1857,1356,1161,2044,600,1631,899,534,379,1538,721,236,845,2357,2046,1731,1120,1633,939,536,1781,2,447,723,1683,687,2621,761,2149,57,1824,405,1504,1023,201,381,1365,2383,2080,248,383,2207,1267,36,804,944,805,766,1123,1459,1689,574,202,1214,808,1935,1024,2384,1369,1423,1600,768,479,1548,1218,1550,1551,1791,1601,1079,505,2456,1694,300,37,2188,986,27,948,1127,1510,813,451,10,858,1908,426,2387,2191,2280,814,101,2118,1980,506,1653,988,270,392,1035,483,1911,1279,169,1427,1132,2346,2422,44,64,225,2445,176,2297,2630,638,2263,668,324,129,325,155,458,1181,130,583,360,45,551,956,1833,552,93,2059,1136,1476,1477,434,131,1236,1378,1138,32,186,1747,1432,554,920,1835,1659,2026,171,23,958,84,1749,2617,703,1565,2324,733,156,734,2325,736,1524,1484,999,1434,87,91,1001,47,738
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2,631
Auf1 hnrnp d0 binds and destabilizes mrna
12
42
2.957375
0.003103
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1761,2035,2226,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,2415,1068,1416,1265,1507,943,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.31336929154874354,-0.5842434527420278,-0.8289885581393346,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,-1.217797716297186,0.21377219628069816,-0.023187036139176026,0.08028608865991266,-0.09379028637419248,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Predicted secreted proteins
12
44
2.955348
0.003123
Q6UWP2,P80303,Q8N128,O60888,P02786,Q9BTY2,Q02818,Q9UMX5,Q9NZ08,Q9HB40,O75718,O94919
Functions
Protein Atlas Protein class
protein_atlas_protein_class
238,43,240,14,264,176,237,20,55,93,158,365
1144,14,158,1620,365,264,1291,1153,1531,2033,625,1850,1533,2038,374,754,2141,1355,1631,1165,43,842,602,237,1596,660,1931,1541,2442,238,240,948,2387,579,1316,1744,176,1703,550,93,55,1709,20,1327
0.14765384784078572,3.5743230764818996,1.2332126975583004,-0.2021240853281833,0.8153380062854007,0.977767688006064,0.04611947228614343,0.14765384784078572,-0.12957783544472734,-0.5842434527420278,0.5570467687489573,-0.3891484207838882,-0.12957783544472734,-0.5842434527420278,0.8153380062854007,0.4359965476908903,-0.705167787937405,0.011628382363652217,-0.2021240853281833,0.14765384784078572,2.3679204497279276,0.3739010427175194,0.5866809767008758,1.0303233973076291,-0.16568914771639728,0.5271655315673739,-0.46621885306434724,-0.12957783544472734,-1.307727538673511,1.0303233973076291,1.0303233973076291,0.3107081753546436,-1.129149687086767,0.6160723009781515,0.04611947228614343,-0.2759642918046235,1.183548528852841,-0.23888251175943867,0.6452247828693638,1.5404174998791007,2.0864437380032115,-0.23888251175943867,3.2332576595140914,0.04611947228614343
2,631
Coated vesicle membrane
11
51
2.946286
0.003216
Q15363,P49755,P49257,Q9Y6B6,Q9Y3B3,O43731,Q15437,Q8N511,Q9Y678,Q15436,P24390
Localization
GO Cellular component
msigdb_gocc
5,143,234,82,53,54,22,121,230,61,123
1951,788,1846,54,1756,1803,2566,1758,1394,1244,2101,264,793,1444,347,2035,494,2037,123,1254,1500,234,143,1819,1205,2141,1408,1678,797,1777,1930,1784,1072,1074,5,61,22,1788,121,2160,1742,412,1945,555,1380,1044,2195,53,230,82,1045
-0.5052379861113006,0.40508352216113896,-0.3891484207838882,2.0864437380032115,-0.31336929154874354,-0.3510973783434665,-2.022972918699234,-0.31336929154874354,-0.023187036139176026,0.08028608865991266,-0.6645376888850335,0.977767688006064,0.40508352216113896,-0.058326639732175146,0.8429236851350608,-0.5842434527420278,0.6741423628769925,-0.5842434527420278,1.3544699048423925,0.08028608865991266,-0.09379028637419248,1.0303233973076291,1.2822041225107923,-0.3510973783434665,0.11412915938872559,-0.705167787937405,-0.023187036139176026,-0.23888251175943867,0.40508352216113896,-0.31336929154874354,-0.46621885306434724,-0.31336929154874354,0.21377219628069816,0.21377219628069816,4.86328444949437,2.0274549169815406,3.1756606722953644,-0.31336929154874354,1.3782415831495038,-0.705167787937405,-0.2759642918046235,0.7875391296424109,-0.46621885306434724,0.6452247828693638,0.011628382363652217,0.24637748849157123,-0.7461197124067016,2.1058970915870394,1.0563168307418604,1.6299370577151888,0.24637748849157123
2,631
Vascular neoplasm
10
30
2.933017
0.003357
P21281,O60762,Q9UJX6,O75874,P48735,O96028,Q9H3P2,Q15437,Q9UBM7,Q15436
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
222,190,273,41,17,140,287,22,23,61
190,2221,41,2132,140,1493,493,830,652,222,1671,1013,1817,1818,1854,1534,17,2273,1775,379,1261,2180,295,61,22,2090,287,23,513,273
1.13319242501366,-0.8289885581393346,2.4038695750039927,-0.705167787937405,1.2822041225107923,-0.09379028637419248,0.6741423628769925,0.3739010427175194,0.5271655315673739,1.0563168307418604,-0.23888251175943867,0.24637748849157123,-0.3510973783434665,-0.3510973783434665,-0.3891484207838882,-0.12957783544472734,3.521809624851483,-0.9131432773169984,-0.31336929154874354,0.8153380062854007,0.08028608865991266,-0.7461197124067016,0.9244343611620436,2.0274549169815406,3.1756606722953644,-0.624229536412293,0.9511996966722966,3.102383344071522,0.6741423628769925,0.977767688006064
2,631
Iron ion homeostasis
7
15
2.932881
0.003358
P61421,P30626,P02786,Q15904,Q9Y487,Q8N511,P30519
Processes and pathways
GO Biological process
msigdb_gobp
167,163,264,145,260,121,127
1391,1530,264,1398,311,1446,127,163,597,167,980,145,121,917,260
-0.023187036139176026,-0.12957783544472734,0.977767688006064,-0.023187036139176026,0.8974686565746289,-0.058326639732175146,1.330541201726474,1.2084658865131082,0.5866809767008758,1.2084658865131082,0.278687675691609,1.2822041225107923,1.3782415831495038,0.3424442560190503,1.0041412915640857
2,631
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
15
49
2.918626
0.003516
P28072,O00233,Q9UJX6,O00487,Q9UL46,P25789,P28074,P25788,Q9UJX3,Q13309,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,273,188,206,350,106,349,126,294,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,1200,1893,1115,1066,142,18,1894,895,2073,378,937,1858,1257,1593,1068,2506,1416,294,1507,943,1544,815,2019,394,2091,731,2555,126,674,273,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,0.11412915938872559,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,0.3424442560190503,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-1.538154279489105,-0.023187036139176026,0.9244343611620436,-0.09379028637419248,0.3107081753546436,-0.12957783544472734,0.40508352216113896,-0.544579561175527,0.8153380062854007,-0.624229536412293,0.46664484400905687,-1.9234564142985089,1.3544699048423925,0.5271655315673739,0.977767688006064,1.107748671810519,0.3424442560190503
2,631
Hedgehog on state
12
41
2.916582
0.003539
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,527,142,18,1894,2073,378,937,1858,1257,1593,1068,1416,2112,1507,943,2278,394,2091,206,922,2129
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,0.6452247828693638,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.21377219628069816,-0.023187036139176026,-0.6645376888850335,-0.09379028637419248,0.3107081753546436,-0.9131432773169984,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503,-0.6645376888850335
2,631
Tcr signaling
13
48
2.91481
0.003559
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49427,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,107,18,142,394,59,62
515,874,132,188,1843,825,929,594,1445,885,59,1011,749,349,350,973,62,34,106,1893,1061,1115,1066,107,142,18,1894,2073,378,1304,937,1858,1257,1593,658,1068,2050,1635,1416,2361,1507,943,806,2237,394,2091,206,922
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,0.5866809767008758,-0.058326639732175146,0.3424442560190503,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.21377219628069816,0.1808662269600239,0.21377219628069816,1.47179933358734,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.04611947228614343,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.5271655315673739,0.21377219628069816,-0.5842434527420278,-0.2021240853281833,-0.023187036139176026,-1.085306619758222,-0.09379028637419248,0.3107081753546436,0.40508352216113896,-0.8289885581393346,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503
2,631
Negative regulation of notch4 signaling
12
40
2.909763
0.003617
P28072,O00233,O00487,Q9UL46,P25789,P28074,P25788,P49721,P49720,Q99436,P20618,P28070
Processes and pathways
Reactome Pathways
msigdb_reactome
34,132,188,206,350,106,349,18,142,394,59,62
515,874,132,188,1843,825,929,1445,59,1011,749,349,350,973,62,34,106,1893,1115,1066,142,18,1894,2073,378,937,1858,1257,1593,568,658,1068,1416,2361,943,394,2091,206,922,737
0.6452247828693638,0.3424442560190503,1.3064533352461962,1.13319242501366,-0.3891484207838882,0.3739010427175194,0.3107081753546436,-0.058326639732175146,2.0274549169815406,0.24637748849157123,0.4359965476908903,0.8429236851350608,0.8429236851350608,0.278687675691609,2.007578507508111,2.561425042425346,1.47179933358734,-0.4275222886859329,0.1808662269600239,0.21377219628069816,1.2822041225107923,3.3458384043052356,-0.4275222886859329,-0.624229536412293,0.8153380062854007,0.3107081753546436,-0.3891484207838882,0.08028608865991266,-0.16568914771639728,0.6160723009781515,0.5271655315673739,0.21377219628069816,-0.023187036139176026,-1.085306619758222,0.3107081753546436,0.8153380062854007,-0.624229536412293,1.107748671810519,0.3424442560190503,0.46664484400905687
2,631