term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Stabilization of p53
| 15
| 40
| 3.330202
| 0.000868
|
Q99436,P60900,O00231,Q9UL46,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,P28074,P61289,P20618,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,563,8,172,355,43,416,415,45,77,645,55,616
|
499,1896,949,1837,689,415,2002,3210,1627,55,1453,1048,416,1849,1337,45,43,77,2071,915,1582,877,918,8,1305,1638,160,645,1347,1348,1518,616,2178,355,1470,172,128,1370,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,-0.22540238496379614,-1.1232104786129942,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,0.3315660934388125,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.5847945955838018,-0.3080441426423994,0.927825637672481,0.0443366457785035,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377
| 3,424
|
Mapk6 mapk4 signaling
| 19
| 50
| 3.326633
| 0.000879
|
Q99436,O00231,P49721,P61289,Q16512,P60900,Q16181,Q9UL46,Q92530,P28072,P25788,O75832,P28070,P20618,P28074,P06493,Q9HCE1,Q14997,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,645,155,160,299,563,172,43,416,415,45,55,77,589,363,355,616
|
499,1896,949,1837,1038,689,415,2455,589,1451,2009,1627,55,2067,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1638,160,1587,645,1347,1348,1518,2025,616,1353,2178,355,1470,299,155,172,128,1370,363,1947,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.25416528674662836,0.5095764645830615,0.8311149234361495,-0.4758552031128107,0.6097285261007889,0.0443366457785035,-0.22540238496379614,-0.035686956378783614,2.7855222848906425,-0.25285839803484295,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,-0.008928939691278415,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,-0.22540238496379614,0.5847945955838018,0.0972732050141189,-0.3080441426423994,0.927825637672481,0.0443366457785035,1.0473214180574488,1.5560133657211266,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.927825637672481,-0.17075981630557494,0.6593914757616174,0.017745346447724377
| 3,424
|
Interleukin 1 signaling
| 19
| 46
| 3.318466
| 0.000905
|
Q99436,O00231,P49721,P61289,P60900,Q9UL46,Q92530,P28072,P25788,O75832,P28070,Q9Y6K9,P20618,O43242,P28074,P09429,Q14997,O15111,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,645,160,563,172,43,416,415,45,315,55,689,77,714,355,483,616
|
499,1896,949,1837,483,689,415,1179,714,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1638,160,745,645,1347,1348,1518,842,1756,616,2178,1206,355,1470,927,172,128,1370,563,1556,315
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.7333815342116367,0.5095764645830615,0.8311149234361495,0.176073624778936,0.4843631223961893,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.45907851980090025,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,-0.08945721189541478,0.5847945955838018,-0.3080441426423994,0.176073624778936,0.927825637672481,0.0443366457785035,0.3315660934388125,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377,1.0235436493047718
| 3,424
|
Auf1 hnrnp d0 binds and destabilizes mrna
| 15
| 42
| 3.300708
| 0.000964
|
Q99436,P60900,O00231,Q9UL46,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,P28074,P61289,P20618,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,563,8,172,355,43,416,415,45,77,645,55,616
|
499,1896,949,1837,689,415,2455,2217,736,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1638,160,645,1347,1348,1518,1308,616,2178,970,355,1470,172,128,1370,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,-0.4758552031128107,-0.33577561888619256,0.45907851980090025,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.12361989908791096,0.5847945955838018,-0.3080441426423994,0.3058415118163126,0.927825637672481,0.0443366457785035,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377
| 3,424
|
Tnfr2 non canonical nf kb pathway
| 16
| 43
| 3.291044
| 0.000998
|
Q99436,P60900,O00231,Q9UL46,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,P28074,O15111,P61289,P20618,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,563,8,172,355,43,416,415,45,77,483,645,55,616
|
499,1896,949,1837,483,689,415,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1638,160,744,645,1347,1348,1518,842,616,2419,2178,1206,355,1470,892,172,128,1370,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.7333815342116367,0.5095764645830615,0.8311149234361495,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.45907851980090025,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.5847945955838018,-0.4476465603203489,-0.3080441426423994,0.176073624778936,0.927825637672481,0.0443366457785035,0.3572158266764965,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377
| 3,424
|
Signaling by notch4
| 15
| 43
| 3.282689
| 0.001028
|
Q99436,P60900,O43242,O00231,Q9UL46,P49721,Q92530,P28072,P25788,O75832,P28070,P28074,P61289,P20618,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,689,499,563,8,172,43,416,415,45,77,645,55,616
|
499,1896,949,1837,689,415,1627,55,1453,1048,416,1849,1337,45,43,77,695,2071,1582,877,918,8,1305,1638,160,645,1347,1348,1518,922,842,616,2178,2648,1206,1470,172,1820,128,1370,563,1556,1667
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,0.5095764645830615,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.3315660934388125,0.38279132997221815,0.5847945955838018,-0.3080441426423994,-0.5896824508203791,0.176073624778936,0.0443366457785035,1.4881976158068801,-0.11647099443820123,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377,-0.035686956378783614
| 3,424
|
G1 s dna damage checkpoints
| 15
| 41
| 3.271713
| 0.001069
|
Q99436,P60900,O00231,Q9UL46,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,P28074,P61289,P20618,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,563,8,172,355,43,416,415,45,77,645,55,616
|
499,1896,949,1837,689,415,2002,3210,1627,55,1092,1453,1048,416,1849,1337,45,43,77,2071,915,1582,877,918,8,1305,1638,160,645,1347,1348,1518,616,2178,355,1470,172,128,1370,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,-0.22540238496379614,-1.1232104786129942,-0.035686956378783614,2.7855222848906425,0.22821236301417117,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,0.3315660934388125,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.5847945955838018,-0.3080441426423994,0.927825637672481,0.0443366457785035,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377
| 3,424
|
Proteasome complex
| 18
| 48
| 3.270469
| 0.001074
|
Q99436,P60900,O00231,Q9UL46,P49721,O43396,Q92530,P28072,Q14997,P25788,O75832,P28070,P28074,Q06323,P54727,P61289,P20618,Q05086
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,160,499,563,8,667,172,43,355,416,415,45,77,616,615,645,55,401
|
499,1896,949,1837,689,667,415,2455,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1052,615,1638,2552,160,645,1347,1348,1518,401,616,2178,355,1470,1528,2032,1358,2039,172,128,1370,563,1556,1612
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.534719116783902,0.8311149234361495,-0.4758552031128107,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,0.25416528674662836,0.5847945955838018,-0.035686956378783614,-0.5325682992306233,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.8553872817591445,0.5847945955838018,-0.3080441426423994,0.927825637672481,0.0443366457785035,0.017745346447724377,-0.22540238496379614,0.0972732050141189,-0.22540238496379614,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377,-0.008928939691278415
| 3,424
|
Degradation of beta catenin by the destruction complex
| 20
| 50
| 3.262698
| 0.001104
|
Q99436,O00231,P49721,P30154,P61289,P60900,Q9UL46,Q92530,P28072,P25788,O75832,P28070,P20618,P30153,P49841,P28074,Q14997,P48729,Q16537,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,264,645,160,563,172,43,416,415,45,55,320,571,77,355,228,516,616
|
499,1896,949,1837,689,415,1627,55,1453,1048,416,1849,1337,45,43,77,320,264,2272,2071,1582,877,228,918,8,571,1305,1638,1750,160,645,1347,1348,1518,842,1919,616,2178,2280,2599,1206,1814,355,1470,516,172,128,1370,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,0.9997056275167767,1.1418385424299435,-0.36360068398579487,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,1.2586797137259673,0.3315660934388125,5.197689907839026,0.6345939747312106,0.12361989908791096,-0.035686956378783614,-0.08945721189541478,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,-0.17075981630557494,0.5847945955838018,-0.3080441426423994,-0.36360068398579487,-0.5610747366914889,0.176073624778936,-0.11647099443820123,0.927825637672481,0.0443366457785035,0.7087847380791157,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377
| 3,424
|
Exopeptidase activity
| 8
| 33
| 3.248544
| 0.00116
|
O75844,O14773,Q9H3G5,Q9HB40,P10619,P42785,Q92820,Q9UIQ6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,162,98,11,139,14,93,29
|
162,64,546,911,505,139,737,3357,1797,2996,14,3240,1000,163,1703,747,1111,850,1268,1874,93,2482,723,2856,98,1604,11,822,1989,1386,1946,767,29
|
1.5108548870512621,2.5835449672827635,0.6593914757616174,0.3315660934388125,0.7087847380791157,1.7124644253307189,0.45907851980090025,-1.565741227335299,-0.11647099443820123,-0.8815663376382865,4.388008865230443,-1.1848376868304877,0.28004145481948706,1.5108548870512621,-0.06252945841594201,0.45907851980090025,0.22821236301417117,0.38279132997221815,0.1498864751122822,-0.14357159543690104,2.210083029251862,-0.4758552031128107,0.4843631223961893,-0.7342769881754115,2.1889413177819854,-0.008928939691278415,4.663727626155535,0.4082932133836793,-0.1980364707364708,0.0972732050141189,-0.17075981630557494,0.45907851980090025,3.614405798250022
| 3,424
|
The role of gtse1 in g2 m progression after g2 checkpoint
| 22
| 50
| 3.235061
| 0.001216
|
Q99436,Q9BUF5,O00231,Q9BVA1,P49721,P61289,P60900,Q9UL46,Q92530,P28072,P25788,O75832,P28070,Q13885,O95067,P20618,P68371,P28074,P06493,P04350,Q14997,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,657,499,269,8,645,160,563,172,43,416,415,45,439,307,55,322,77,589,218,355,616
|
499,1896,949,1837,689,415,307,218,3210,589,1180,1133,2006,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,2551,1638,160,645,1347,1348,1518,322,616,2178,439,355,1470,784,172,128,1370,657,269,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,1.0235436493047718,1.2818779400411169,-1.1232104786129942,0.6097285261007889,0.176073624778936,0.20218202998275958,-0.22540238496379614,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.5325682992306233,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.9997056275167767,0.5847945955838018,-0.3080441426423994,0.806778655356379,0.927825637672481,0.0443366457785035,0.4337220787410696,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.5597916419271479,1.1418385424299435,0.6593914757616174,0.017745346447724377
| 3,424
|
Interleukin 1 family signaling
| 20
| 48
| 3.209247
| 0.001331
|
Q99436,O00231,P49721,P61289,P60900,Q9UL46,Q92530,P28072,P25788,O75832,P40763,P28070,Q9Y6K9,P20618,O43242,P28074,P09429,Q14997,O15111,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,645,160,563,172,43,416,415,673,45,315,55,689,77,714,355,483,616
|
499,1896,949,1837,483,689,415,1179,714,1627,55,1453,1048,416,1849,1337,45,43,77,2071,673,1582,877,918,8,1305,1638,160,745,645,1347,1348,1518,842,1756,2560,616,2178,1206,355,1470,927,172,128,1370,563,1556,315
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.7333815342116367,0.5095764645830615,0.8311149234361495,0.176073624778936,0.4843631223961893,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,0.534719116783902,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.45907851980090025,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,-0.08945721189541478,-0.5325682992306233,0.5847945955838018,-0.3080441426423994,0.176073624778936,0.927825637672481,0.0443366457785035,0.3315660934388125,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377,1.0235436493047718
| 3,424
|
Clec7a dectin 1 signaling
| 25
| 48
| 3.175836
| 0.001494
|
Q99436,P61081,O00231,P49721,P61289,P60900,Q15750,Q9UL46,Q92530,P28072,P25788,O75832,P28070,Q9Y6K9,O43865,P20618,O43242,P28074,P63208,P48556,Q8TBC4,Q14997,O15111,Q06323,P61088
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,744,499,8,645,160,927,563,172,43,416,415,45,315,545,55,689,77,842,877,892,355,483,616,745
|
499,1896,949,1837,483,689,545,415,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1638,160,744,745,645,1347,1348,1518,842,1003,616,2228,2178,1206,355,1470,927,892,172,128,1370,563,1556,315
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.7333815342116367,0.5095764645830615,0.6593914757616174,0.8311149234361495,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.45907851980090025,0.45907851980090025,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.28004145481948706,0.5847945955838018,-0.33577561888619256,-0.3080441426423994,0.176073624778936,0.927825637672481,0.0443366457785035,0.3315660934388125,0.3572158266764965,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377,1.0235436493047718
| 3,424
|
Uch proteinases
| 8
| 47
| 3.174848
| 0.001499
|
Q99436,Q8NB78,P60900,P49721,P28072,P28070,P28074,P20618
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,1,160,8,43,45,77,55
|
499,1896,949,1837,1498,689,415,2454,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,2838,1305,1638,160,645,1347,1348,1518,882,616,2178,355,1470,2032,1,172,128,1370,3391,563,1556,2492,1167,1612
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.017745346447724377,0.5095764645830615,0.8311149234361495,-0.4758552031128107,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,-0.7342769881754115,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.3572158266764965,0.5847945955838018,-0.3080441426423994,0.927825637672481,0.0443366457785035,-0.22540238496379614,7.071723102728203,1.4881976158068801,1.8665043911430075,0.0972732050141189,-1.899302791396063,0.6593914757616174,0.017745346447724377,-0.4758552031128107,0.20218202998275958,-0.008928939691278415
| 3,424
|
Abc transporter disorders
| 17
| 44
| 3.128064
| 0.00176
|
Q99436,P60900,O00231,Q9NUN5,Q9UL46,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,P28074,Q9GZP9,P61289,P20618,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,234,563,8,172,355,43,416,415,45,77,707,645,55,616
|
499,1896,949,1837,689,1041,415,2539,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1638,2552,160,645,1347,1348,1518,616,2178,355,1470,172,128,1370,3199,707,234,824,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.25416528674662836,0.8311149234361495,-0.5325682992306233,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,-0.5325682992306233,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.5847945955838018,-0.3080441426423994,0.927825637672481,0.0443366457785035,1.4881976158068801,1.8665043911430075,0.0972732050141189,-1.0925841770213,0.5095764645830615,1.2586797137259673,0.4082932133836793,0.6593914757616174,0.017745346447724377
| 3,424
|
Signaling by hedgehog
| 29
| 64
| 3.125666
| 0.001774
|
Q99436,Q9BUF5,O00231,Q9BVA1,P49721,P61289,Q8NCM8,P60900,Q9UL46,Q92530,P28072,P25788,O75832,P28070,Q9GZP9,P10644,Q13885,P20618,Q2M1P5,Q96J02,P68371,P49841,P28074,O75665,P04350,Q14997,P48729,Q9Y366,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,657,499,269,8,645,157,160,563,172,43,416,415,45,707,53,439,55,183,66,322,571,77,95,218,355,228,381,616
|
499,1896,949,1837,689,95,415,218,2541,53,2005,1451,2009,1627,55,1453,1048,416,1849,1337,45,43,77,1910,2071,1582,877,228,918,8,571,1305,1638,2552,160,645,1347,1348,1518,842,322,616,2178,1206,1704,439,355,1470,183,3148,157,172,66,128,1370,657,269,707,824,563,1284,1556,381,770
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,2.1889413177819854,0.8311149234361495,1.2818779400411169,-0.5325682992306233,2.825471169603632,-0.22540238496379614,0.0443366457785035,-0.22540238496379614,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.17075981630557494,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,1.2586797137259673,0.3315660934388125,5.197689907839026,0.6345939747312106,0.12361989908791096,-0.035686956378783614,-0.5325682992306233,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.9997056275167767,0.5847945955838018,-0.3080441426423994,0.176073624778936,-0.06252945841594201,0.806778655356379,0.927825637672481,0.0443366457785035,1.442725285577121,-1.0316990493048206,1.5560133657211266,1.4881976158068801,2.5631377808237996,1.8665043911430075,0.0972732050141189,0.5597916419271479,1.1418385424299435,0.5095764645830615,0.4082932133836793,0.6593914757616174,0.1498864751122822,0.017745346447724377,0.9037421707307038,0.45907851980090025
| 3,424
|
Transcriptional regulation by runx3
| 7
| 41
| 3.124713
| 0.00178
|
Q99436,P60900,P49721,P28072,P28070,P28074,P20618
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,8,43,45,77,55
|
499,1896,949,1837,689,415,3210,1627,55,2414,1453,1048,416,1849,1337,45,43,77,2272,2071,915,1582,877,918,8,1305,1638,160,645,1347,1348,1518,616,2178,2648,1470,172,128,1370,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,-1.1232104786129942,-0.035686956378783614,2.7855222848906425,-0.4476465603203489,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.36360068398579487,-0.25285839803484295,0.3315660934388125,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.5847945955838018,-0.3080441426423994,-0.5896824508203791,0.0443366457785035,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377
| 3,424
|
Transcriptional regulation by runx2
| 21
| 53
| 3.119512
| 0.001812
|
Q99436,O00231,P49721,P61289,P60900,Q9UL46,Q92530,P28072,P25788,O75832,P28070,P31751,P20618,O43242,P49841,P28074,P11802,P04150,P06493,Q14997,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,645,160,563,172,43,416,415,45,308,55,689,571,77,450,213,589,355,616
|
499,1896,949,1837,689,415,213,589,2407,450,2006,1627,55,1453,1048,416,1849,1093,1337,45,43,77,2271,695,308,2071,1512,1582,877,918,8,571,1305,1638,160,645,1347,1348,1518,842,616,2178,1146,1206,355,1470,172,895,128,1370,563,2442,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,1.3050204064717228,0.6097285261007889,-0.4476465603203489,0.7823779947173779,-0.22540238496379614,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.22821236301417117,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.36360068398579487,0.5095764645830615,1.0235436493047718,-0.25285839803484295,0.017745346447724377,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.6345939747312106,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.5847945955838018,-0.3080441426423994,0.20218202998275958,0.176073624778936,0.927825637672481,0.0443366457785035,1.4881976158068801,0.3572158266764965,1.8665043911430075,0.0972732050141189,0.6593914757616174,-0.4476465603203489,0.017745346447724377
| 3,424
|
Regulation of hmox1 expression and activity
| 16
| 46
| 3.104673
| 0.001905
|
Q99436,P60900,O00231,Q9UL46,P49721,Q92530,P09601,P28072,Q14997,P25788,O75832,P28070,P28074,P61289,P20618,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,563,8,172,138,43,355,416,415,45,77,645,55,616
|
499,1896,949,1837,689,415,138,1627,1628,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1638,160,645,1347,1348,1518,842,2799,1003,616,2178,1146,1206,1704,355,1470,3080,172,128,1370,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,1.7124644253307189,-0.035686956378783614,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,-0.7051470219004672,0.28004145481948706,0.5847945955838018,-0.3080441426423994,0.20218202998275958,0.176073624778936,-0.06252945841594201,0.927825637672481,0.0443366457785035,-0.9412694483017089,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377
| 3,424
|
C type lectin receptors clrs
| 21
| 52
| 3.097296
| 0.001953
|
Q99436,O00231,P49721,P61289,Q16512,P60900,Q9UL46,Q92530,P28072,P25788,O75832,P28070,Q9Y6K9,O43865,P20618,O43242,P28074,Q14997,O15111,Q06323,P61088
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,645,155,160,563,172,43,416,415,45,315,545,55,689,77,355,483,616,745
|
499,1896,949,1837,483,689,545,415,1451,2009,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1638,160,744,745,645,1347,1348,1518,842,1003,616,2228,1353,2178,1206,355,1470,927,155,892,172,128,1370,563,1556,315
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.7333815342116367,0.5095764645830615,0.6593914757616174,0.8311149234361495,0.0443366457785035,-0.22540238496379614,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.45907851980090025,0.45907851980090025,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.28004145481948706,0.5847945955838018,-0.33577561888619256,0.0972732050141189,-0.3080441426423994,0.176073624778936,0.927825637672481,0.0443366457785035,0.3315660934388125,1.5560133657211266,0.3572158266764965,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377,1.0235436493047718
| 3,424
|
Runx1 regulates transcription of genes involved in differentiation of hscs
| 14
| 42
| 3.090803
| 0.001996
|
Q99436,P60900,Q96J02,O00231,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,P28074,P20618,P84243
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,66,499,8,172,355,43,416,415,45,77,55,438
|
499,1896,949,1837,689,415,3366,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1638,160,645,1347,1348,1518,3368,438,1056,616,2178,355,1470,172,66,128,1370,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,-1.631208032298414,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,-1.631208032298414,0.806778655356379,0.25416528674662836,0.5847945955838018,-0.3080441426423994,0.927825637672481,0.0443366457785035,1.4881976158068801,2.5631377808237996,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377
| 3,424
|
Defective cftr causes cystic fibrosis
| 16
| 43
| 3.090322
| 0.001999
|
Q99436,P60900,O00231,Q9UL46,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,P28074,Q9GZP9,P61289,P20618,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,563,8,172,355,43,416,415,45,77,707,645,55,616
|
499,1896,949,1837,689,1041,415,2539,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1638,2552,160,645,1347,1348,1518,616,2178,355,1470,172,128,1370,3199,707,824,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.25416528674662836,0.8311149234361495,-0.5325682992306233,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,-0.5325682992306233,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.5847945955838018,-0.3080441426423994,0.927825637672481,0.0443366457785035,1.4881976158068801,1.8665043911430075,0.0972732050141189,-1.0925841770213,0.5095764645830615,0.4082932133836793,0.6593914757616174,0.017745346447724377
| 3,424
|
Orc1 removal from chromatin
| 17
| 50
| 3.058219
| 0.002227
|
Q99436,P60900,O00231,Q9Y619,Q9UL46,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,P25205,P28074,P61289,P20618,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,166,563,8,172,355,43,416,415,45,176,77,645,55,616
|
499,1896,949,1837,689,2899,415,1627,55,1092,176,1453,1048,416,1849,1337,45,43,77,1457,1577,1049,2071,1582,877,918,8,1460,1305,1638,160,645,1347,1348,1518,842,616,2178,1146,1206,971,355,1470,172,128,1370,2672,563,1556,166
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,-0.7928613254372211,0.8311149234361495,-0.035686956378783614,2.7855222848906425,0.22821236301417117,1.465487864832413,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,0.0443366457785035,-0.008928939691278415,0.25416528674662836,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.0443366457785035,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.5847945955838018,-0.3080441426423994,0.20218202998275958,0.176073624778936,0.3058415118163126,0.927825637672481,0.0443366457785035,1.4881976158068801,1.8665043911430075,0.0972732050141189,-0.5896824508203791,0.6593914757616174,0.017745346447724377,1.5108548870512621
| 3,424
|
Pcp ce pathway
| 18
| 51
| 3.057337
| 0.002233
|
Q99436,P60900,P09497,O00231,Q9UL46,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,P28074,P09496,P61289,P20618,Q06323,P07737
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,692,499,563,8,172,355,43,416,415,45,77,271,645,55,616,435
|
499,1896,949,1837,689,415,1621,2629,435,271,692,1451,1627,55,1453,1048,416,1849,1337,45,43,77,1910,2071,1582,877,918,8,1305,1695,1638,2074,160,645,1347,1348,1518,2025,1975,2077,616,2178,2649,355,1470,172,2434,128,1370,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,-0.035686956378783614,-0.5896824508203791,0.806778655356379,1.11829750855662,0.5095764645830615,0.0443366457785035,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.17075981630557494,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.06252945841594201,-0.035686956378783614,-0.25285839803484295,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,-0.22540238496379614,-0.1980364707364708,-0.25285839803484295,0.5847945955838018,-0.3080441426423994,-0.5896824508203791,0.927825637672481,0.0443366457785035,1.4881976158068801,-0.4476465603203489,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377
| 3,424
|
Proteasome degradation
| 7
| 43
| 2.962647
| 0.00305
|
Q99436,P49721,P28072,P28070,P28074,P20618,P30511
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
128,8,43,45,77,55,30
|
499,1896,1837,689,415,3024,1400,2791,2866,485,3366,1627,55,2221,1453,1048,416,1849,1337,45,43,77,30,2071,1582,1301,877,918,8,1305,1638,160,645,1347,1348,1518,616,2178,1470,128,1370,563,1556
|
0.7087847380791157,-0.17075981630557494,-0.14357159543690104,0.5095764645830615,0.8311149234361495,-0.9113604219611866,0.07084569120510033,-0.7051470219004672,-0.763514707401799,0.7333815342116367,-1.631208032298414,-0.035686956378783614,2.7855222848906425,-0.33577561888619256,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,3.558497153180639,-0.25285839803484295,-0.008928939691278415,0.12361989908791096,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.5847945955838018,-0.3080441426423994,0.0443366457785035,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377
| 3,424
|
Switching of origins to a post replicative state
| 16
| 57
| 2.939884
| 0.003283
|
Q99436,P60900,O00231,Q9Y619,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,Q13042,P25205,P28074,Q96DE5,P20618
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,166,8,172,355,43,416,415,45,273,176,77,443,55
|
499,1896,949,1837,689,2899,415,1627,55,1092,176,1453,1048,416,1849,1337,45,43,77,2170,1457,1577,1049,2071,1582,877,918,8,1460,1305,1638,160,645,1347,1348,1518,842,616,273,2178,1146,1206,971,355,1470,172,443,128,1370,1940,2672,1236,1492,1555,563,1556,166
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,-0.7928613254372211,0.8311149234361495,-0.035686956378783614,2.7855222848906425,0.22821236301417117,1.465487864832413,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.3080441426423994,0.0443366457785035,-0.008928939691278415,0.25416528674662836,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.0443366457785035,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.5847945955838018,1.11829750855662,-0.3080441426423994,0.20218202998275958,0.176073624778936,0.3058415118163126,0.927825637672481,0.0443366457785035,1.4881976158068801,0.806778655356379,1.8665043911430075,0.0972732050141189,-0.17075981630557494,-0.5896824508203791,0.176073624778936,0.0443366457785035,0.017745346447724377,0.6593914757616174,0.017745346447724377,1.5108548870512621
| 3,424
|
protease
| 7
| 41
| 2.93489
| 0.003337
|
Q99436,P60900,P49721,P28072,P28070,P28074,P20618
|
Functions
|
Panther Protein class
|
panther_protein_class
|
128,160,8,43,45,77,55
|
1896,1837,689,546,3109,1627,55,1453,1048,416,1849,1337,45,43,77,2071,836,1582,877,918,8,3240,1638,272,160,2465,1347,1348,1518,2178,1708,128,1370,1717,2572,2487,1989,2530,1556,864,2210
|
-0.17075981630557494,-0.14357159543690104,0.5095764645830615,0.6593914757616174,-1.001437451234241,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,0.38279132997221815,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,-1.1848376868304877,-0.035686956378783614,1.11829750855662,1.5334600233386158,-0.4758552031128107,0.0972732050141189,0.0972732050141189,0.017745346447724377,-0.3080441426423994,-0.06252945841594201,1.8665043911430075,0.0972732050141189,-0.06252945841594201,-0.5325682992306233,-0.4758552031128107,-0.1980364707364708,-0.5041621214531338,0.017745346447724377,0.38279132997221815,-0.3080441426423994
| 3,424
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 6
| 31
| 2.92536
| 0.003441
|
Q8NB78,Q16850,P30519,Q15800,Q9BU89,O75845
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
1,131,34,84,119,89
|
2862,2102,2294,2755,2537,89,3226,2541,138,1739,1960,2834,34,592,2417,3069,1594,84,131,1009,403,1476,1595,1112,1981,1,119,1379,1279,1436,1894
|
-0.763514707401799,-0.28040536208862893,-0.3915202453943403,-0.6761236824753828,-0.5325682992306233,2.231181939560065,-1.1539611641322176,-0.5325682992306233,1.7124644253307189,-0.08945721189541478,-0.1980364707364708,-0.7342769881754115,3.4458619829507984,0.6097285261007889,-0.4476465603203489,-0.9412694483017089,-0.008928939691278415,2.2942243165759035,1.82273284893905,0.28004145481948706,0.8553872817591445,0.0443366457785035,-0.008928939691278415,0.22821236301417117,-0.1980364707364708,7.071723102728203,1.953484693197824,0.0972732050141189,0.1498864751122822,0.07084569120510033,-0.14357159543690104
| 3,424
|
Sphingolipid metabolic process
| 12
| 34
| 2.89899
| 0.003744
|
P30153,P27544,Q06136,O15270,Q96G23,P07602,O95470,Q9NZD2,Q8NCC3,P50897,Q13510,P06280
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
320,103,108,204,206,115,239,347,345,26,91,153
|
829,204,1327,239,368,153,548,115,2792,639,777,2010,103,320,26,1003,108,746,91,2916,2316,2375,345,206,1318,2932,1552,2097,3128,347,1993,2252,3183,867
|
0.38279132997221815,1.3511395792365377,0.0972732050141189,1.2354253422253956,0.9037421707307038,1.5560133657211266,0.6593914757616174,1.975114183919561,-0.7051470219004672,0.5597916419271479,0.4337220787410696,-0.22540238496379614,2.1039414474895977,0.9997056275167767,3.743824687447206,0.28004145481948706,2.061178120380909,0.45907851980090025,2.231181939560065,-0.7928613254372211,-0.3915202453943403,-0.41953522517290537,0.9518470676402865,1.3511395792365377,0.12361989908791096,-0.7928613254372211,0.017745346447724377,-0.25285839803484295,-1.001437451234241,0.9518470676402865,-0.1980364707364708,-0.33577561888619256,-1.0620808335875023,0.38279132997221815
| 3,424
|
Tcr signaling
| 16
| 49
| 2.898436
| 0.00375
|
Q99436,P60900,O00231,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,P28074,Q9Y6K9,O15111,P20618,P50552,Q16512
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,8,172,355,43,416,415,45,77,315,483,55,536,155
|
499,1896,3413,949,1837,483,689,415,1627,2167,55,1453,1048,416,1849,1337,45,43,77,2071,1744,1582,877,918,8,536,1305,1638,160,745,645,1347,1348,1518,842,616,1353,2178,1206,355,1470,155,1218,172,128,1370,563,1556,315
|
0.7087847380791157,-0.17075981630557494,-2.6951538272125575,0.3058415118163126,-0.14357159543690104,0.7333815342116367,0.5095764645830615,0.8311149234361495,-0.035686956378783614,-0.3080441426423994,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.08945721189541478,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.6841215566363612,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.45907851980090025,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.5847945955838018,0.0972732050141189,-0.3080441426423994,0.176073624778936,0.927825637672481,0.0443366457785035,1.5560133657211266,0.176073624778936,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377,1.0235436493047718
| 3,424
|
Beta catenin independent wnt signaling
| 19
| 56
| 2.872434
| 0.004073
|
Q99436,O00231,P49721,P09496,P61289,P60900,Q9UL46,Q92530,P28072,P25788,O75832,P28070,P20618,P07737,P09497,P28074,Q9HCE1,Q14997,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,271,645,160,563,172,43,416,415,45,55,435,692,77,363,355,616
|
499,1896,949,1837,689,415,1621,2629,435,271,692,1451,1627,55,1453,1048,416,1849,1337,45,43,77,1910,2272,2071,1582,877,918,8,1305,1695,1638,2074,160,645,1347,1348,1518,2025,1975,1752,2077,616,2228,2178,2649,355,1470,172,2434,128,1370,363,1828,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,-0.035686956378783614,-0.5896824508203791,0.806778655356379,1.11829750855662,0.5095764645830615,0.0443366457785035,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.17075981630557494,-0.36360068398579487,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.06252945841594201,-0.035686956378783614,-0.25285839803484295,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,-0.22540238496379614,-0.1980364707364708,-0.08945721189541478,-0.25285839803484295,0.5847945955838018,-0.33577561888619256,-0.3080441426423994,-0.5896824508203791,0.927825637672481,0.0443366457785035,1.4881976158068801,-0.4476465603203489,1.8665043911430075,0.0972732050141189,0.927825637672481,-0.11647099443820123,0.6593914757616174,0.017745346447724377
| 3,424
|
Protein insertion into membrane
| 11
| 33
| 2.84575
| 0.004431
|
P46379,Q9Y5J6,O94826,P49069,Q15629,Q8N8Q8,Q9Y5J7,Q9Y584,P30419,Q9NS69,O14737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
35,431,136,321,144,334,208,250,370,60,94
|
94,868,501,1618,136,1180,370,2070,35,321,2766,2127,1526,144,2916,1649,2479,423,1875,334,2380,2382,3017,60,2204,1389,2582,1835,250,431,208,1037,2292
|
2.1889413177819854,0.3572158266764965,0.7087847380791157,-0.035686956378783614,1.7346152657608775,0.176073624778936,0.9037421707307038,-0.25285839803484295,3.408070428891878,0.9997056275167767,-0.6761236824753828,-0.28040536208862893,0.017745346447724377,1.69026439193255,-0.7928613254372211,-0.035686956378783614,-0.4758552031128107,0.8311149234361495,-0.14357159543690104,0.9758069147141267,-0.41953522517290537,-0.41953522517290537,-0.8815663376382865,2.624243454701938,-0.3080441426423994,0.0972732050141189,-0.5325682992306233,-0.11647099443820123,1.212114435826368,0.8311149234361495,1.3511395792365377,0.28004145481948706,-0.36360068398579487
| 3,424
|
Receptor
| 9
| 32
| 2.841714
| 0.004487
|
Q567V2,P20645,Q9NR77,Q8WTV0,A6NIH7,Q9UQB8,Q14108,Q9HAV4,Q9UFC0
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
325,97,262,37,191,17,19,180,127
|
191,1038,1617,1998,1957,1621,2629,2678,506,97,1580,1257,3072,19,2471,887,325,2317,403,1213,37,1219,3199,707,180,1548,262,1388,127,945,17,732
|
1.3970402287838317,0.25416528674662836,-0.035686956378783614,-0.22540238496379614,-0.1980364707364708,-0.035686956378783614,-0.5896824508203791,-0.6183924757333895,0.7087847380791157,2.1889413177819854,-0.008928939691278415,0.1498864751122822,-0.9412694483017089,4.016451430021635,-0.4758552031128107,0.3572158266764965,0.9997056275167767,-0.3915202453943403,0.8553872817591445,0.176073624778936,3.408070428891878,0.176073624778936,-1.0925841770213,0.5095764645830615,1.465487864832413,0.017745346447724377,1.165321436994088,0.0972732050141189,1.8883193828815668,0.3315660934388125,4.194804424150486,0.4843631223961893
| 3,424
|
Proteasome core complex
| 7
| 15
| 2.798848
| 0.005129
|
P60900,Q99436,P49721,P28072,P28070,P28074,P20618
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
160,128,8,43,45,77,55
|
1837,55,1453,1048,416,1849,1337,45,43,77,918,8,160,172,128
|
-0.14357159543690104,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,0.3315660934388125,5.197689907839026,1.5334600233386158,1.4881976158068801,1.8665043911430075
| 3,424
|
Entry into host
| 7
| 32
| 2.798674
| 0.005131
|
P19474,Q96J02,Q8WTV0,O15118,P35613,Q14108,Q9BTY2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
121,66,37,106,78,19,158
|
175,1729,106,1328,911,2678,589,2541,2994,2106,1737,2268,1185,121,2761,78,2974,840,2911,969,19,2471,1706,1418,37,2776,66,935,158,685,1079,2585
|
1.465487864832413,-0.08945721189541478,2.061178120380909,0.0972732050141189,0.3315660934388125,-0.6183924757333895,0.6097285261007889,-0.5325682992306233,-0.8815663376382865,-0.28040536208862893,-0.08945721189541478,-0.36360068398579487,0.176073624778936,1.9100875739304093,-0.6761236824753828,2.3776962925175247,-0.8518859430798013,0.38279132997221815,-0.7928613254372211,0.3058415118163126,4.016451430021635,-0.4758552031128107,-0.06252945841594201,0.07084569120510033,3.408070428891878,-0.6761236824753828,2.5631377808237996,0.3315660934388125,1.5560133657211266,0.534719116783902,0.25416528674662836,-0.5325682992306233
| 3,424
|
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1
| 17
| 48
| 2.774676
| 0.005526
|
Q99436,P60900,O00231,Q9UL46,P49721,Q92530,Q14997,P28072,P25788,O75832,P28070,Q13042,P28074,Q96DE5,P61289,P20618,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,563,8,172,355,43,416,415,45,273,77,443,645,55,616
|
499,1896,949,1837,3384,689,415,1627,55,1453,1048,416,1849,1337,45,43,77,2170,2071,1582,877,918,8,1305,2551,1638,160,645,1347,1348,1518,616,3295,273,2178,1146,355,1470,172,443,128,1370,1940,1236,1492,1555,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,-1.7975625050538029,0.5095764645830615,0.8311149234361495,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.3080441426423994,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.5325682992306233,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.5847945955838018,-1.3096322187119562,1.11829750855662,-0.3080441426423994,0.20218202998275958,0.927825637672481,0.0443366457785035,1.4881976158068801,0.806778655356379,1.8665043911430075,0.0972732050141189,-0.17075981630557494,0.176073624778936,0.0443366457785035,0.017745346447724377,0.6593914757616174,0.017745346447724377
| 3,424
|
Antigen processing cross presentation
| 19
| 55
| 2.756601
| 0.005841
|
Q99436,O00231,P49721,Q9UIQ6,P30511,P60900,Q9UL46,Q92530,P28072,P25788,O75832,P28070,Q9Y6K9,P20618,Q03519,P28074,Q14997,P10321,O15111
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,29,30,160,563,172,43,416,415,45,315,55,182,77,355,485,483
|
2061,499,1896,949,1837,483,689,2756,415,3024,1400,714,485,1627,55,1453,1048,416,1849,2681,1337,45,43,77,3164,30,2071,1582,877,918,8,1305,1638,3035,160,645,2766,1347,1348,1518,844,182,616,3038,2178,355,1470,172,128,1370,584,29,563,1556,315
|
-0.25285839803484295,0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.7333815342116367,0.5095764645830615,-0.6761236824753828,0.8311149234361495,-0.9113604219611866,0.07084569120510033,0.4843631223961893,0.7333815342116367,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,-0.6183924757333895,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-1.0620808335875023,3.558497153180639,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,-0.9113604219611866,1.5334600233386158,0.5597916419271479,-0.6761236824753828,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,1.442725285577121,0.5847945955838018,-0.9113604219611866,-0.3080441426423994,0.927825637672481,0.0443366457785035,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6345939747312106,3.614405798250022,0.6593914757616174,0.017745346447724377,1.0235436493047718
| 3,424
|
Endopeptidase activity
| 21
| 65
| 2.745106
| 0.006049
|
Q99436,P49721,P52888,Q13043,P55210,Q2T9J0,Q9UPU5,Q5JRX3,P60900,O14773,P28072,P28070,P20618,O75844,Q96K76,P28074,O43847,P42892,P67812,Q9BYT8,Q9BXS4
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,8,10,265,272,274,282,279,160,162,43,45,55,64,69,77,212,92,220,379,255
|
162,634,1327,212,3185,64,713,2410,1185,1847,55,2222,1849,45,43,77,1797,3164,2357,3385,836,92,1513,1802,918,8,10,1000,1052,272,160,220,1465,265,747,2031,474,274,1529,279,1151,2317,1111,1651,3080,1820,815,377,1114,1157,69,625,2983,128,2816,1022,2856,255,379,2249,767,282,1167,2583,2584
|
1.5108548870512621,0.5597916419271479,0.0972732050141189,1.3050204064717228,-1.0925841770213,2.5835449672827635,0.4843631223961893,-0.4476465603203489,0.176073624778936,-0.14357159543690104,2.7855222848906425,-0.33577561888619256,-0.14357159543690104,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.11647099443820123,-1.0620808335875023,-0.41953522517290537,-1.7975625050538029,0.38279132997221815,2.210083029251862,0.017745346447724377,-0.11647099443820123,0.3315660934388125,5.197689907839026,4.663727626155535,0.28004145481948706,0.25416528674662836,1.11829750855662,1.5334600233386158,1.2818779400411169,0.0443366457785035,1.1418385424299435,0.45907851980090025,-0.22540238496379614,0.7579124526698604,1.11829750855662,0.017745346447724377,1.0946979225093583,0.20218202998275958,-0.3915202453943403,0.22821236301417117,-0.035686956378783614,-0.9412694483017089,-0.11647099443820123,0.4082932133836793,0.9037421707307038,0.22821236301417117,0.20218202998275958,2.5016819168115965,0.5847945955838018,-0.8518859430798013,1.8665043911430075,-0.7051470219004672,0.28004145481948706,-0.7342769881754115,1.1887466003329457,0.9037421707307038,-0.33577561888619256,0.45907851980090025,1.0946979225093583,0.20218202998275958,-0.5325682992306233,-0.5325682992306233
| 3,424
|
Proteasome, subunit alpha/beta [IPR001353]
| 6
| 14
| 2.730804
| 0.006318
|
Q99436,P49721,P28072,P28074,P28070,P20618
|
Sequence
|
InterPro Family
|
interpro_family
|
128,8,43,77,45,55
|
1837,55,1453,1048,416,1849,1337,45,43,77,918,8,160,128
|
-0.14357159543690104,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,0.3315660934388125,5.197689907839026,1.5334600233386158,1.8665043911430075
| 3,424
|
Lysosome
| 26
| 52
| 2.730704
| 0.00632
|
O43681,P54802,P11717,P10619,P16278,Q14108,P09496,P50897,P06280,O14773,Q9UJY4,P11117,P06865,P04066,P15586,Q9UMR5,O75503,Q9Y2T2,Q8NCC3,Q13510,Q10567,P20645,O15118,P07602,P04062,Q99523
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
501,259,506,139,639,19,271,26,153,162,562,169,548,691,319,72,73,207,345,91,593,97,106,115,368,527
|
1996,3378,1083,162,106,501,1617,73,368,691,153,548,115,2792,271,692,993,139,169,2268,506,1402,2008,319,639,777,97,3409,26,1000,259,1055,2120,800,2077,593,91,19,928,345,1540,1020,527,2816,1601,1993,1390,562,1785,72,207,866
|
-0.22540238496379614,-1.7305497067588773,0.22821236301417117,1.5108548870512621,2.061178120380909,0.7087847380791157,-0.035686956378783614,2.4398700711321197,0.9037421707307038,0.5095764645830615,1.5560133657211266,0.6593914757616174,1.975114183919561,-0.7051470219004672,1.11829750855662,0.5095764645830615,0.28004145481948706,1.7124644253307189,1.4881976158068801,-0.36360068398579487,0.7087847380791157,0.07084569120510033,-0.22540238496379614,0.9997056275167767,0.5597916419271479,0.4337220787410696,2.1889413177819854,-2.5063238140704884,3.743824687447206,0.28004145481948706,1.165321436994088,0.25416528674662836,-0.28040536208862893,0.4082932133836793,-0.25285839803484295,0.6097285261007889,2.231181939560065,4.016451430021635,0.3315660934388125,0.9518470676402865,0.017745346447724377,0.28004145481948706,0.7087847380791157,-0.7051470219004672,-0.008928939691278415,-0.1980364707364708,0.0972732050141189,0.6593914757616174,-0.08945721189541478,2.460513937219191,1.3511395792365377,0.38279132997221815
| 3,424
|
Molecular carrier activity
| 9
| 33
| 2.728308
| 0.006366
|
P52294,Q8TEX9,Q92973,Q8N8Q8,O00505,Q9Y5J7,O00410,Q9HAV4,P40855
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
9,405,300,334,175,208,330,180,400
|
330,175,1898,1038,868,670,1675,1568,2217,2356,400,2361,9,644,1640,806,2127,1526,1649,423,1875,334,405,300,981,2144,1718,180,3017,2204,1165,208,1168
|
0.9758069147141267,1.465487864832413,-0.17075981630557494,0.25416528674662836,0.3572158266764965,0.534719116783902,-0.06252945841594201,-0.008928939691278415,-0.33577561888619256,-0.41953522517290537,0.8553872817591445,-0.41953522517290537,5.066275194941922,0.5597916419271479,-0.035686956378783614,0.4082932133836793,-0.28040536208862893,0.017745346447724377,-0.035686956378783614,0.8311149234361495,-0.14357159543690104,0.9758069147141267,0.8553872817591445,1.0473214180574488,0.3058415118163126,-0.28040536208862893,-0.06252945841594201,1.465487864832413,-0.8815663376382865,-0.3080441426423994,0.20218202998275958,1.3511395792365377,0.20218202998275958
| 3,424
|
Endopeptidase complex
| 19
| 55
| 2.724493
| 0.00644
|
Q99436,O00231,P49721,O43292,P61289,Q05086,P60900,Q9UL46,O43396,Q92530,P28072,P25788,O75832,P28070,P20618,P28074,Q14997,P54727,Q06323
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,499,8,634,645,401,160,563,667,172,43,416,415,45,55,77,355,615,616
|
499,1896,949,1837,689,634,667,1327,415,2455,1847,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1052,615,1638,2552,160,645,1347,1348,1518,401,616,2178,355,1470,1528,2032,1358,2039,172,815,2656,2048,128,1370,3264,563,1556,1612
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.5597916419271479,0.534719116783902,0.0972732050141189,0.8311149234361495,-0.4758552031128107,-0.14357159543690104,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,0.25416528674662836,0.5847945955838018,-0.035686956378783614,-0.5325682992306233,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.8553872817591445,0.5847945955838018,-0.3080441426423994,0.927825637672481,0.0443366457785035,0.017745346447724377,-0.22540238496379614,0.0972732050141189,-0.22540238496379614,1.4881976158068801,0.4082932133836793,-0.5896824508203791,-0.22540238496379614,1.8665043911430075,0.0972732050141189,-1.215841528185196,0.6593914757616174,0.017745346447724377,-0.008928939691278415
| 3,424
|
Abc family proteins mediated transport
| 19
| 54
| 2.698496
| 0.006965
|
Q99436,O00231,P49721,P61289,P40855,P60900,Q9UL46,Q92530,P28072,P08183,P25788,O75832,P28070,Q9GZP9,P20618,P28074,Q14997,O15439,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,645,400,160,563,172,43,168,416,415,45,707,55,77,355,484,616
|
499,1896,949,1837,484,689,2864,1041,415,2539,1401,168,1627,1961,55,1453,1048,416,1849,1337,45,43,77,1136,1963,2071,400,1582,877,918,8,1305,1638,2552,1972,160,645,1347,1348,1518,616,2178,355,1470,1653,172,128,1370,3199,707,2576,824,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.7333815342116367,0.5095764645830615,-0.763514707401799,0.25416528674662836,0.8311149234361495,-0.5325682992306233,0.07084569120510033,1.4881976158068801,-0.035686956378783614,-0.1980364707364708,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,0.20218202998275958,-0.1980364707364708,-0.25285839803484295,0.8553872817591445,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,-0.5325682992306233,-0.1980364707364708,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.5847945955838018,-0.3080441426423994,0.927825637672481,0.0443366457785035,-0.035686956378783614,1.4881976158068801,1.8665043911430075,0.0972732050141189,-1.0925841770213,0.5095764645830615,-0.5325682992306233,0.4082932133836793,0.6593914757616174,0.017745346447724377
| 3,424
|
Mitochondrial protein import
| 12
| 40
| 2.687276
| 0.007204
|
P21796,Q13505,O94826,O60830,Q9NX63,Q99595,Q9Y5J7,Q8N4H5,Q9Y584,Q5JRX3,O14925,Q9NS69
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
3,199,136,12,411,16,208,404,250,279,305,60
|
305,1291,12,3290,2593,3185,1999,136,957,2216,2003,2459,3239,1846,2108,3,3316,3269,1465,199,1472,1865,279,404,1929,1367,16,3123,2665,729,60,411,1784,2582,1835,250,431,208,1037,2292
|
1.0235436493047718,0.12361989908791096,4.629595354354387,-1.3096322187119562,-0.5610747366914889,-1.0925841770213,-0.22540238496379614,1.7346152657608775,0.3058415118163126,-0.33577561888619256,-0.22540238496379614,-0.4758552031128107,-1.1848376868304877,-0.14357159543690104,-0.28040536208862893,6.325246102229058,-1.3728244416731277,-1.2469741986696485,0.0443366457785035,1.374117034728647,0.0443366457785035,-0.14357159543690104,1.0946979225093583,0.8553872817591445,-0.17075981630557494,0.0972732050141189,4.2830041272536015,-1.001437451234241,-0.5896824508203791,0.4843631223961893,2.624243454701938,0.8553872817591445,-0.08945721189541478,-0.5325682992306233,-0.11647099443820123,1.212114435826368,0.8311149234361495,1.3511395792365377,0.28004145481948706,-0.36360068398579487
| 3,424
|
Fc epsilon receptor fceri signaling
| 19
| 53
| 2.67757
| 0.007416
|
Q99436,O00231,P49721,Q16512,P60900,Q9UL46,Q92530,P28072,P25788,O75832,P28070,Q9Y6K9,O43865,P20618,P28074,Q14997,P62993,O15111,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,155,160,563,172,43,416,415,45,315,545,55,77,355,353,483,616
|
499,1896,3413,949,1837,483,689,545,415,1627,2167,55,1453,1048,416,1849,1093,1337,45,43,77,2271,2071,1582,877,918,8,1305,1638,160,745,645,1347,1348,1518,353,2025,842,616,2228,1353,2178,1206,355,1470,927,155,172,128,1370,563,1556,315
|
0.7087847380791157,-0.17075981630557494,-2.6951538272125575,0.3058415118163126,-0.14357159543690104,0.7333815342116367,0.5095764645830615,0.6593914757616174,0.8311149234361495,-0.035686956378783614,-0.3080441426423994,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.22821236301417117,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.36360068398579487,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.45907851980090025,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.927825637672481,-0.22540238496379614,0.38279132997221815,0.5847945955838018,-0.33577561888619256,0.0972732050141189,-0.3080441426423994,0.176073624778936,0.927825637672481,0.0443366457785035,0.3315660934388125,1.5560133657211266,1.4881976158068801,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377,1.0235436493047718
| 3,424
|
Nucleophile aminohydrolases, N-terminal [IPR029055]
| 6
| 18
| 2.664657
| 0.007707
|
Q99436,P49721,P28072,P28074,P28070,P20618
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
128,8,43,77,45,55
|
1837,1045,55,1453,1048,416,1849,1337,45,43,77,918,8,160,573,1203,128,2530
|
-0.14357159543690104,0.25416528674662836,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,0.3315660934388125,5.197689907839026,1.5334600233386158,0.6345939747312106,0.176073624778936,1.8665043911430075,-0.5041621214531338
| 3,424
|
Translation factors
| 15
| 36
| 2.663699
| 0.007729
|
Q9NR50,P29692,Q9H074,O75153,P55010,Q14240,P63241,P49770,Q15056,Q9UI10,P60228,O75821,O75822,O15372,P11940
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
561,569,362,5,71,354,881,352,617,245,920,830,533,688,736
|
1325,1564,688,1174,5,830,533,1401,1845,736,1686,1795,1961,1047,1135,1187,569,352,71,1516,2020,920,967,1588,881,1308,2645,2421,2027,1759,1645,354,617,362,561,245
|
0.0972732050141189,-0.008928939691278415,0.5095764645830615,0.176073624778936,5.959748464908521,0.38279132997221815,0.6841215566363612,0.07084569120510033,-0.14357159543690104,0.45907851980090025,-0.06252945841594201,-0.11647099443820123,-0.1980364707364708,0.25416528674662836,0.20218202998275958,0.176073624778936,0.6345939747312106,0.927825637672481,2.460513937219191,0.017745346447724377,-0.22540238496379614,0.3315660934388125,0.3058415118163126,-0.008928939691278415,0.3572158266764965,0.12361989908791096,-0.5896824508203791,-0.4476465603203489,-0.22540238496379614,-0.08945721189541478,-0.035686956378783614,0.927825637672481,0.5847945955838018,0.927825637672481,0.6593914757616174,1.2354253422253956
| 3,424
|
transporter
| 20
| 61
| 2.660269
| 0.007808
|
Q9NR77,P52294,Q8TEX9,O60830,Q99595,O43772,O75694,Q9Y619,Q92973,O00505,O15397,Q9HAV4,Q567V2,O15321,Q8N8Q8,O00410,P55735,Q9NUN5,P41440,Q9Y584
|
Functions
|
Panther Protein class
|
panther_protein_class
|
262,9,405,12,16,25,397,166,300,175,294,180,325,75,334,330,214,234,110,250
|
330,175,1083,1898,1038,75,294,1291,501,25,12,397,1043,2356,2303,110,963,2974,2361,9,2362,2224,2682,1969,644,214,1345,2766,2418,806,1526,325,2850,3369,786,2377,623,334,2609,2432,405,1655,300,2697,981,1371,16,1318,725,1545,1718,446,180,1027,262,234,1165,2099,250,1168,166
|
0.9758069147141267,1.465487864832413,0.22821236301417117,-0.17075981630557494,0.25416528674662836,2.3776962925175247,1.0473214180574488,0.12361989908791096,0.7087847380791157,3.7988551199513982,4.629595354354387,0.8553872817591445,0.25416528674662836,-0.41953522517290537,-0.3915202453943403,2.039729696998139,0.3058415118163126,-0.8518859430798013,-0.41953522517290537,5.066275194941922,-0.41953522517290537,-0.33577561888619256,-0.6183924757333895,-0.1980364707364708,0.5597916419271479,1.3050204064717228,0.0972732050141189,-0.6761236824753828,-0.4476465603203489,0.4082932133836793,0.017745346447724377,0.9997056275167767,-0.7342769881754115,-1.631208032298414,0.4337220787410696,-0.41953522517290537,0.5847945955838018,0.9758069147141267,-0.5610747366914889,-0.4476465603203489,0.8553872817591445,-0.035686956378783614,1.0473214180574488,-0.6183924757333895,0.3058415118163126,0.0972732050141189,4.2830041272536015,0.12361989908791096,0.4843631223961893,0.017745346447724377,-0.06252945841594201,0.806778655356379,1.465487864832413,0.28004145481948706,1.165321436994088,1.2586797137259673,0.20218202998275958,-0.25285839803484295,1.212114435826368,0.20218202998275958,1.5108548870512621
| 3,424
|
Predicted secreted proteins
| 14
| 58
| 2.653439
| 0.007968
|
Q8WUJ1,Q9H6E4,Q8NBM8,P43490,P04083,Q9HB40,P80303,P14174,O60888,O00584,Q02818,Q9UM22,Q9BTY2,Q9UMX5
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
32,184,134,38,40,11,15,143,79,82,116,56,158,190
|
82,1729,2537,79,1087,1177,609,911,40,1179,1248,3025,2679,714,2942,143,1185,2718,611,834,38,919,1854,1855,2120,2911,15,1753,1201,116,2078,242,1413,2806,3388,373,1111,750,651,134,2888,32,3196,358,2088,1599,2660,158,819,1604,184,2742,11,767,1778,56,190,2623
|
2.315154463757088,-0.08945721189541478,-0.5325682992306233,2.3568902177129267,0.22821236301417117,0.176073624778936,0.5847945955838018,0.3315660934388125,3.2172107186041283,0.176073624778936,0.1498864751122822,-0.9113604219611866,-0.6183924757333895,0.4843631223961893,-0.8223180083817365,1.69026439193255,0.176073624778936,-0.6472058630830041,0.5847945955838018,0.38279132997221815,3.3891277801711235,0.3315660934388125,-0.14357159543690104,-0.14357159543690104,-0.28040536208862893,-0.7928613254372211,4.370570465939998,-0.08945721189541478,0.176073624778936,1.953484693197824,-0.25285839803484295,1.2354253422253956,0.07084569120510033,-0.7051470219004672,-1.8652235299580648,0.9037421707307038,0.22821236301417117,0.45907851980090025,0.5597916419271479,1.7567172231726083,-0.763514707401799,3.483529521359152,-1.0925841770213,0.927825637672481,-0.25285839803484295,-0.008928939691278415,-0.5896824508203791,1.5560133657211266,0.4082932133836793,-0.008928939691278415,1.442725285577121,-0.6472058630830041,4.663727626155535,0.45907851980090025,-0.08945721189541478,2.7855222848906425,1.4199095256546266,-0.5610747366914889
| 3,424
|
Apc c mediated degradation of cell cycle proteins
| 18
| 55
| 2.62611
| 0.008637
|
Q99436,P60900,O00231,Q9UL46,P49721,Q92530,Q14997,P28072,P06493,P25788,O75832,P28070,Q13042,P28074,Q96DE5,P20618,Q06323,O60566
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,499,563,8,172,355,43,589,416,415,45,273,77,443,55,616,63
|
499,1896,949,1837,3384,689,2063,63,415,589,2006,1627,55,1092,1453,1048,416,1849,1337,45,43,77,2170,2071,1582,877,918,8,1305,2551,1638,160,645,1347,1348,1518,842,616,3295,273,2178,1146,1206,355,1470,172,443,128,1370,1940,1236,1492,1555,563,1556
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,-1.7975625050538029,0.5095764645830615,-0.25285839803484295,2.5835449672827635,0.8311149234361495,0.6097285261007889,-0.22540238496379614,-0.035686956378783614,2.7855222848906425,0.22821236301417117,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.3080441426423994,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.5325682992306233,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.5847945955838018,-1.3096322187119562,1.11829750855662,-0.3080441426423994,0.20218202998275958,0.176073624778936,0.927825637672481,0.0443366457785035,1.4881976158068801,0.806778655356379,1.8665043911430075,0.0972732050141189,-0.17075981630557494,0.176073624778936,0.0443366457785035,0.017745346447724377,0.6593914757616174,0.017745346447724377
| 3,424
|
Vacuolar lumen
| 22
| 66
| 2.576132
| 0.009991
|
P54802,P10619,Q14108,Q9BTY2,P50897,P06280,O14773,P11117,Q9UM22,Q9NQ11,P68371,Q8IV08,P15586,Q9UMR5,O00584,P20839,Q13510,Q92820,P07602,P46976,Q8NHP8,O00560
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
259,139,19,158,26,153,162,169,56,65,322,68,319,72,82,88,91,93,115,241,117,251
|
251,82,3378,162,501,3209,368,691,153,548,3025,318,115,2792,1180,993,139,169,2217,2297,1402,2008,319,639,777,88,2271,535,1579,3409,241,1256,26,1967,1193,1000,717,259,2552,2875,2120,322,1522,1918,1003,2279,91,19,1524,68,2886,117,93,2612,1370,757,2816,158,2390,901,65,2098,1993,56,72,2210
|
1.1887466003329457,2.315154463757088,-1.7305497067588773,1.5108548870512621,0.7087847380791157,-1.1232104786129942,0.9037421707307038,0.5095764645830615,1.5560133657211266,0.6593914757616174,-0.9113604219611866,0.9997056275167767,1.975114183919561,-0.7051470219004672,0.176073624778936,0.28004145481948706,1.7124644253307189,1.4881976158068801,-0.33577561888619256,-0.3915202453943403,0.07084569120510033,-0.22540238496379614,0.9997056275167767,0.5597916419271479,0.4337220787410696,2.2732523402364393,-0.36360068398579487,0.6841215566363612,-0.008928939691278415,-2.5063238140704884,1.2354253422253956,0.1498864751122822,3.743824687447206,-0.1980364707364708,0.176073624778936,0.28004145481948706,0.4843631223961893,1.165321436994088,-0.5325682992306233,-0.763514707401799,-0.28040536208862893,0.9997056275167767,0.017745346447724377,-0.17075981630557494,0.28004145481948706,-0.36360068398579487,2.231181939560065,4.016451430021635,0.017745346447724377,2.5016819168115965,-0.763514707401799,1.953484693197824,2.210083029251862,-0.5610747366914889,0.0972732050141189,0.45907851980090025,-0.7051470219004672,1.5560133657211266,-0.41953522517290537,0.3572158266764965,2.5835449672827635,-0.25285839803484295,-0.1980364707364708,2.7855222848906425,2.460513937219191,-0.3080441426423994
| 3,424
|
Regulation of actin filament length
| 13
| 44
| 2.568902
| 0.010202
|
O95429,Q9NYL9,Q96F07,P58546,Q13045,P62993,Q9UQB8,Q9NUQ9,Q14019,Q6ZU35,P50552,P35080,P07737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,235,425,385,421,353,17,149,538,24,536,399,435
|
1670,2589,2401,952,2497,1177,96,435,738,399,1964,1691,1692,1140,2307,1096,536,1968,385,1856,1195,353,2469,1003,1977,421,2422,538,1006,2808,24,577,1934,425,1375,149,235,2205,1723,1078,17,1609,1665,1128
|
-0.06252945841594201,-0.5610747366914889,-0.4476465603203489,0.3058415118163126,-0.5041621214531338,0.176073624778936,2.1889413177819854,0.806778655356379,0.45907851980090025,0.8553872817591445,-0.1980364707364708,-0.06252945841594201,-0.06252945841594201,0.20218202998275958,-0.3915202453943403,0.22821236301417117,0.6841215566363612,-0.1980364707364708,0.8795962071847374,-0.14357159543690104,0.176073624778936,0.927825637672481,-0.4758552031128107,0.28004145481948706,-0.1980364707364708,0.8311149234361495,-0.4476465603203489,0.6841215566363612,0.28004145481948706,-0.7051470219004672,3.8171415688003916,0.6345939747312106,-0.17075981630557494,0.8311149234361495,0.0972732050141189,1.6680148523611502,1.2586797137259673,-0.3080441426423994,-0.06252945841594201,0.25416528674662836,4.194804424150486,-0.008928939691278415,-0.035686956378783614,0.22821236301417117
| 3,424
|
Biliary tract abnormality
| 11
| 26
| 2.552691
| 0.010689
|
Q96J02,Q9NUN5,Q9UJW0,Q14739,P09601,Q13043,P14174,O96028,Q14108,P07602,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,234,497,386,138,265,143,295,19,115,368
|
501,1733,295,2790,368,115,138,143,2008,1506,2357,2945,1465,265,2280,19,386,1475,1114,66,1662,234,1993,497,2582,1168
|
0.7087847380791157,-0.08945721189541478,1.0473214180574488,-0.7051470219004672,0.9037421707307038,1.975114183919561,1.7124644253307189,1.69026439193255,-0.22540238496379614,0.017745346447724377,-0.41953522517290537,-0.8223180083817365,0.0443366457785035,1.1418385424299435,-0.36360068398579487,4.016451430021635,0.8795962071847374,0.0443366457785035,0.22821236301417117,2.5631377808237996,-0.035686956378783614,1.2586797137259673,-0.1980364707364708,0.7333815342116367,-0.5325682992306233,0.20218202998275958
| 3,424
|
Actin filament polymerization
| 14
| 45
| 2.530353
| 0.011395
|
O95429,Q12768,Q9NYL9,Q96F07,P58546,Q13045,P62993,Q9UQB8,Q9NUQ9,Q14019,Q6ZU35,P50552,P35080,P07737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,324,235,425,385,421,353,17,149,538,24,536,399,435
|
1670,2589,2401,952,1567,1177,96,435,738,399,1964,1691,1692,1140,2307,1096,536,1968,2506,385,1856,353,2025,2469,1003,324,1977,421,2422,538,1006,2808,24,577,1934,425,1375,149,235,2205,1078,17,1665,686,1128
|
-0.06252945841594201,-0.5610747366914889,-0.4476465603203489,0.3058415118163126,-0.008928939691278415,0.176073624778936,2.1889413177819854,0.806778655356379,0.45907851980090025,0.8553872817591445,-0.1980364707364708,-0.06252945841594201,-0.06252945841594201,0.20218202998275958,-0.3915202453943403,0.22821236301417117,0.6841215566363612,-0.1980364707364708,-0.5041621214531338,0.8795962071847374,-0.14357159543690104,0.927825637672481,-0.22540238496379614,-0.4758552031128107,0.28004145481948706,0.9997056275167767,-0.1980364707364708,0.8311149234361495,-0.4476465603203489,0.6841215566363612,0.28004145481948706,-0.7051470219004672,3.8171415688003916,0.6345939747312106,-0.17075981630557494,0.8311149234361495,0.0972732050141189,1.6680148523611502,1.2586797137259673,-0.3080441426423994,0.25416528674662836,4.194804424150486,-0.035686956378783614,0.534719116783902,0.22821236301417117
| 3,424
|
Leukocyte proliferation
| 13
| 40
| 2.529284
| 0.01143
|
Q96J02,Q92990,P04083,P78540,P17812,P49366,P14174,Q9HCL2,P00813,P30825,P10644,P04062,Q16512
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,390,40,489,507,229,143,49,146,253,53,368,155
|
566,992,146,911,368,40,1400,3210,714,53,3239,1684,143,507,1251,1297,1093,2271,253,874,2272,836,229,840,1698,489,1143,1350,1003,2649,155,1820,390,2925,1425,66,2323,791,49,1160
|
0.6345939747312106,0.28004145481948706,1.6680148523611502,0.3315660934388125,0.9037421707307038,3.2172107186041283,0.07084569120510033,-1.1232104786129942,0.4843631223961893,2.825471169603632,-1.1848376868304877,-0.06252945841594201,1.69026439193255,0.7087847380791157,0.1498864751122822,0.12361989908791096,0.22821236301417117,-0.36360068398579487,1.1887466003329457,0.3572158266764965,-0.36360068398579487,0.38279132997221815,1.2586797137259673,0.38279132997221815,-0.06252945841594201,0.7333815342116367,0.20218202998275958,0.0972732050141189,0.28004145481948706,-0.5896824508203791,1.5560133657211266,-0.11647099443820123,0.8795962071847374,-0.7928613254372211,0.07084569120510033,2.5631377808237996,-0.3915202453943403,0.4337220787410696,3.0230665383232367,0.20218202998275958
| 3,424
|
Dna replication pre initiation
| 16
| 64
| 2.504052
| 0.012278
|
Q99436,P60900,Q9NR33,Q9Y619,P49721,Q92530,P52294,P28072,Q14997,P25788,O75832,P28070,P25205,P28074,P20618,P15927
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,233,166,8,172,9,43,355,416,415,45,176,77,55,369
|
499,1896,949,1837,689,2899,2452,415,1134,369,3366,1627,55,1092,176,1453,1048,416,1849,1252,1337,45,43,77,1457,1577,1049,1509,2071,1582,877,1190,1852,918,8,1460,1305,9,1638,2553,160,645,1347,1348,1518,3368,438,616,677,2178,971,806,355,1470,2237,172,128,1370,233,1434,2672,563,1556,166
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,-0.7928613254372211,-0.4758552031128107,0.8311149234361495,0.20218202998275958,0.9037421707307038,-1.631208032298414,-0.035686956378783614,2.7855222848906425,0.22821236301417117,1.465487864832413,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.1498864751122822,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,0.0443366457785035,-0.008928939691278415,0.25416528674662836,0.017745346447724377,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.176073624778936,-0.14357159543690104,0.3315660934388125,5.197689907839026,0.0443366457785035,0.12361989908791096,5.066275194941922,-0.035686956378783614,-0.5325682992306233,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,-1.631208032298414,0.806778655356379,0.5847945955838018,0.534719116783902,-0.3080441426423994,0.3058415118163126,0.4082932133836793,0.927825637672481,0.0443366457785035,-0.33577561888619256,1.4881976158068801,1.8665043911430075,0.0972732050141189,1.2586797137259673,0.07084569120510033,-0.5896824508203791,0.6593914757616174,0.017745346447724377,1.5108548870512621
| 3,424
|
Negative regulation of immune system process
| 17
| 52
| 2.484958
| 0.012957
|
Q9H000,Q96J02,Q9Y3Z3,Q92990,O15347,Q96FV9,P09601,P04083,Q16539,P28070,P14174,Q9HCL2,P00813,P10644,P19474,Q16512,P30511
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
427,66,498,390,448,268,138,40,455,45,143,49,146,53,121,155,30
|
448,1086,1177,146,3024,40,1400,2407,714,138,53,143,1505,2167,121,1453,45,996,30,695,874,1910,2272,3269,2546,836,674,1342,3034,489,1700,3140,1978,2649,1101,155,455,2234,2378,1713,390,268,1425,66,1276,427,49,3362,730,498,1167,2494
|
0.7823779947173779,0.22821236301417117,0.176073624778936,1.6680148523611502,-0.9113604219611866,3.2172107186041283,0.07084569120510033,-0.4476465603203489,0.4843631223961893,1.7124644253307189,2.825471169603632,1.69026439193255,0.017745346447724377,-0.3080441426423994,1.9100875739304093,0.0443366457785035,3.081664317034927,0.28004145481948706,3.558497153180639,0.5095764645830615,0.3572158266764965,-0.17075981630557494,-0.36360068398579487,-1.2469741986696485,-0.5325682992306233,0.38279132997221815,0.534719116783902,0.0972732050141189,-0.9113604219611866,0.7333815342116367,-0.06252945841594201,-1.0316990493048206,-0.1980364707364708,-0.5896824508203791,0.22821236301417117,1.5560133657211266,0.7823779947173779,-0.33577561888619256,-0.41953522517290537,-0.06252945841594201,0.8795962071847374,1.1418385424299435,0.07084569120510033,2.5631377808237996,0.1498864751122822,0.8311149234361495,3.0230665383232367,-1.5983998609621628,0.4843631223961893,0.7333815342116367,0.20218202998275958,-0.4758552031128107
| 3,424
|
Regulation of leukocyte proliferation
| 8
| 26
| 2.450053
| 0.014284
|
Q96J02,P04083,P49366,P14174,Q9HCL2,P00813,P10644,Q16512
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,40,229,143,49,146,53,155
|
566,146,911,40,1400,714,53,143,1251,1093,2271,253,2272,836,229,840,489,1350,2649,155,390,2925,1425,66,2323,49
|
0.6345939747312106,1.6680148523611502,0.3315660934388125,3.2172107186041283,0.07084569120510033,0.4843631223961893,2.825471169603632,1.69026439193255,0.1498864751122822,0.22821236301417117,-0.36360068398579487,1.1887466003329457,-0.36360068398579487,0.38279132997221815,1.2586797137259673,0.38279132997221815,0.7333815342116367,0.0972732050141189,-0.5896824508203791,1.5560133657211266,0.8795962071847374,-0.7928613254372211,0.07084569120510033,2.5631377808237996,-0.3915202453943403,3.0230665383232367
| 3,424
|
Serine hydrolase activity
| 7
| 21
| 2.446563
| 0.014423
|
O14773,Q9H3G5,Q9HB40,P10619,P42785,Q2T9J0,P67812
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
162,98,11,139,14,274,220
|
162,1327,546,139,2410,1797,2357,14,1802,2362,1000,220,474,274,1529,279,2317,1268,2249,98,11
|
1.5108548870512621,0.0972732050141189,0.6593914757616174,1.7124644253307189,-0.4476465603203489,-0.11647099443820123,-0.41953522517290537,4.388008865230443,-0.11647099443820123,-0.41953522517290537,0.28004145481948706,1.2818779400411169,0.7579124526698604,1.11829750855662,0.017745346447724377,1.0946979225093583,-0.3915202453943403,0.1498864751122822,-0.33577561888619256,2.1889413177819854,4.663727626155535
| 3,424
|
Phosphatidylinositol phosphate binding
| 8
| 37
| 2.426397
| 0.01525
|
Q9NQ11,Q13045,O00560,P53367,O60443,P53365,P35080,Q9NV70
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
65,421,251,178,20,90,399,329
|
1169,2213,251,1498,2535,20,1328,3062,3025,435,2010,695,399,1514,90,178,1977,421,2724,1261,1760,1871,1422,1366,1223,1986,1375,1073,1319,1117,2392,65,329,823,1392,867,1240
|
0.176073624778936,-0.33577561888619256,1.1887466003329457,0.017745346447724377,-0.5325682992306233,3.9081517315608365,0.0972732050141189,-0.9412694483017089,-0.9113604219611866,0.806778655356379,-0.22540238496379614,0.5095764645830615,0.8553872817591445,0.017745346447724377,2.231181939560065,1.465487864832413,-0.1980364707364708,0.8311149234361495,-0.6472058630830041,0.1498864751122822,-0.08945721189541478,-0.14357159543690104,0.07084569120510033,0.0972732050141189,0.176073624778936,-0.1980364707364708,0.0972732050141189,0.25416528674662836,0.12361989908791096,0.22821236301417117,-0.41953522517290537,2.5835449672827635,0.9997056275167767,0.4082932133836793,0.0972732050141189,0.38279132997221815,0.176073624778936
| 3,424
|
Hand polydactyly
| 12
| 36
| 2.417108
| 0.015644
|
Q12768,Q96J42,Q14739,O43924,Q13045,O96028,Q9BXW9,Q15125,Q2M1P5,O75845,Q8NCM8,O75665
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
324,99,386,7,421,295,478,209,183,89,157,95
|
3225,3413,7,464,95,89,1733,295,2833,1906,1800,2225,1584,698,1465,324,421,2280,386,3074,701,209,183,2518,157,1767,2385,99,759,478,2393,1663,1829,2397,1284,665
|
-1.1539611641322176,-2.6951538272125575,5.246628713778516,0.7579124526698604,2.1889413177819854,2.231181939560065,-0.08945721189541478,1.0473214180574488,-0.7342769881754115,-0.17075981630557494,-0.11647099443820123,-0.33577561888619256,-0.008928939691278415,0.5095764645830615,0.0443366457785035,0.9997056275167767,0.8311149234361495,-0.36360068398579487,0.8795962071847374,-0.9412694483017089,0.5095764645830615,1.3281074939758217,1.442725285577121,-0.5041621214531338,1.5560133657211266,-0.08945721189541478,-0.41953522517290537,2.167756556317077,0.45907851980090025,0.7579124526698604,-0.41953522517290537,-0.035686956378783614,-0.11647099443820123,-0.41953522517290537,0.1498864751122822,0.5597916419271479
| 3,424
|
Secondary alcohol metabolic process
| 13
| 44
| 2.385301
| 0.017065
|
Q16850,Q9BQE5,Q8WTV0,Q14739,O15118,Q15392,O75874,Q15125,Q15800,P35610,O75845,P04062,P48735
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,67,37,386,106,44,46,209,84,240,89,368,28
|
106,3163,1041,89,46,2345,2539,3209,368,1179,1683,610,1960,3254,3166,240,3031,3032,436,28,1303,3341,1193,1053,2120,2227,2950,2802,746,1644,1594,386,209,1355,44,2514,84,131,37,3123,67,1552,1663,1723
|
2.061178120380909,-1.0620808335875023,0.25416528674662836,2.231181939560065,3.0621659370708794,-0.41953522517290537,-0.5325682992306233,-1.1232104786129942,0.9037421707307038,0.176073624778936,-0.06252945841594201,0.5847945955838018,-0.1980364707364708,-1.215841528185196,-1.0620808335875023,1.2354253422253956,-0.9113604219611866,-0.9113604219611866,0.806778655356379,3.614405798250022,0.12361989908791096,-1.4686434583977295,0.176073624778936,0.25416528674662836,-0.28040536208862893,-0.33577561888619256,-0.8223180083817365,-0.7051470219004672,0.45907851980090025,-0.035686956378783614,-0.008928939691278415,0.8795962071847374,1.3281074939758217,0.0972732050141189,3.1011287111609,-0.5041621214531338,2.2942243165759035,1.82273284893905,3.408070428891878,-1.001437451234241,2.522206469103894,0.017745346447724377,-0.035686956378783614,-0.06252945841594201
| 3,424
|
Antigen processing ubiquitination proteasome degradation
| 23
| 87
| 2.384897
| 0.017084
|
Q99436,O00231,Q92990,P49721,P52888,Q13042,Q8NEZ5,Q05086,Q9UIQ6,P60900,P55786,Q92530,Q96PU5,P28072,P28070,P25788,O75832,P20618,Q96J02,P28074,Q9UBS8,Q14997,P19474
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,390,8,10,273,541,401,29,160,163,172,302,43,45,416,415,55,66,77,496,355,121
|
2060,499,1896,949,1837,689,415,2000,1734,2165,1627,121,55,2221,1453,1048,416,1849,1337,45,43,77,1797,2170,2071,1582,1301,877,918,8,1305,10,1638,163,160,744,1463,745,645,1347,1348,1518,842,1199,401,616,3295,273,2178,1146,1206,1415,1704,747,2180,2181,355,1470,2081,1528,888,647,1766,1215,2039,541,892,172,390,1541,66,302,128,1370,1023,1427,1940,496,29,1236,1492,1555,563,1950,2442,1556,988
|
-0.25285839803484295,0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.8311149234361495,-0.22540238496379614,-0.08945721189541478,-0.3080441426423994,-0.035686956378783614,1.9100875739304093,2.7855222848906425,-0.33577561888619256,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.11647099443820123,-0.3080441426423994,-0.25285839803484295,-0.008928939691278415,0.12361989908791096,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,4.663727626155535,-0.035686956378783614,1.5108548870512621,1.5334600233386158,0.45907851980090025,0.0443366457785035,0.45907851980090025,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.176073624778936,0.8553872817591445,0.5847945955838018,-1.3096322187119562,1.11829750855662,-0.3080441426423994,0.20218202998275958,0.176073624778936,0.07084569120510033,-0.06252945841594201,0.45907851980090025,-0.3080441426423994,-0.3080441426423994,0.927825637672481,0.0443366457785035,-0.25285839803484295,0.017745346447724377,0.3572158266764965,0.5597916419271479,-0.08945721189541478,0.176073624778936,-0.22540238496379614,0.6841215566363612,0.3572158266764965,1.4881976158068801,0.8795962071847374,0.017745346447724377,2.5631377808237996,1.0473214180574488,1.8665043911430075,0.0972732050141189,0.28004145481948706,0.07084569120510033,-0.17075981630557494,0.7333815342116367,3.614405798250022,0.176073624778936,0.0443366457785035,0.017745346447724377,0.6593914757616174,-0.17075981630557494,-0.4476465603203489,0.017745346447724377,0.3058415118163126
| 3,424
|
Regulation of t cell activation
| 11
| 37
| 2.378491
| 0.017384
|
Q96J02,Q92990,P04083,P49366,O96005,Q9HCL2,P00813,Q9BXW9,Q9NUQ9,P10644,P30825
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,390,40,229,226,49,146,478,149,53,253
|
1996,1083,2495,226,566,146,911,40,1400,2407,714,53,3239,1251,253,695,874,2272,1744,836,229,1342,840,489,2560,3140,2649,2233,2378,2286,390,2925,1425,66,478,49,149
|
-0.22540238496379614,0.22821236301417117,-0.5041621214531338,1.2586797137259673,0.6345939747312106,1.6680148523611502,0.3315660934388125,3.2172107186041283,0.07084569120510033,-0.4476465603203489,0.4843631223961893,2.825471169603632,-1.1848376868304877,0.1498864751122822,1.1887466003329457,0.5095764645830615,0.3572158266764965,-0.36360068398579487,-0.08945721189541478,0.38279132997221815,1.2586797137259673,0.0972732050141189,0.38279132997221815,0.7333815342116367,-0.5325682992306233,-1.0316990493048206,-0.5896824508203791,-0.33577561888619256,-0.41953522517290537,-0.36360068398579487,0.8795962071847374,-0.7928613254372211,0.07084569120510033,2.5631377808237996,0.7579124526698604,3.0230665383232367,1.6680148523611502
| 3,424
|
Anion transmembrane transport
| 11
| 43
| 2.378311
| 0.017392
|
O60831,Q9UHG3,P21796,Q9Y619,Q9Y4C2,P45880,P08183,P41440,Q9H2D1,O15439,P30825
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
465,2,3,166,414,13,168,110,446,484,253
|
484,2830,465,1999,2538,2265,2678,168,2994,1846,2108,3,253,1963,110,13,512,2224,2682,2276,2684,2367,700,2080,1418,1314,3301,598,1481,727,1376,446,3200,2489,2780,1825,862,2,1784,1724,414,166,1242
|
0.7333815342116367,-0.7342769881754115,0.7579124526698604,-0.22540238496379614,-0.5325682992306233,-0.36360068398579487,-0.6183924757333895,1.4881976158068801,-0.8815663376382865,-0.14357159543690104,-0.28040536208862893,6.325246102229058,1.1887466003329457,-0.1980364707364708,2.039729696998139,4.561049497959283,0.7087847380791157,-0.33577561888619256,-0.6183924757333895,-0.36360068398579487,-0.6183924757333895,-0.41953522517290537,0.5095764645830615,-0.25285839803484295,0.07084569120510033,0.12361989908791096,-1.3096322187119562,0.6097285261007889,0.0443366457785035,0.4843631223961893,0.0972732050141189,0.806778655356379,-1.0925841770213,-0.4758552031128107,-0.6761236824753828,-0.11647099443820123,0.38279132997221815,6.870655213788565,-0.08945721189541478,-0.06252945841594201,0.8553872817591445,1.5108548870512621,0.176073624778936
| 3,424
|
Receptor
| 16
| 47
| 2.377376
| 0.017436
|
P24390,P20645,Q8WTV0,Q14739,P23229,Q99523,P11717,P06493,O15118,P35613,Q14108,P04150,P30825,P55899,Q9NS69,Q9UBG0
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
33,97,37,386,286,527,506,589,106,78,19,213,253,537,60,584
|
948,1729,2939,106,586,1957,911,213,2678,589,3112,2106,1737,1333,1571,2268,506,1185,97,286,33,1630,253,78,537,840,2911,925,2806,19,2471,386,1418,1150,37,2776,1541,527,2957,938,60,1388,584,944,2896,687,2585
|
0.3058415118163126,-0.08945721189541478,-0.8223180083817365,2.061178120380909,0.6097285261007889,-0.1980364707364708,0.3315660934388125,1.3050204064717228,-0.6183924757333895,0.6097285261007889,-1.001437451234241,-0.28040536208862893,-0.08945721189541478,0.0972732050141189,-0.008928939691278415,-0.36360068398579487,0.7087847380791157,0.176073624778936,2.1889413177819854,1.0710393665641098,3.4458619829507984,-0.035686956378783614,1.1887466003329457,2.3776962925175247,0.6841215566363612,0.38279132997221815,-0.7928613254372211,0.3315660934388125,-0.7051470219004672,4.016451430021635,-0.4758552031128107,0.8795962071847374,0.07084569120510033,0.20218202998275958,3.408070428891878,-0.6761236824753828,0.017745346447724377,0.7087847380791157,-0.8223180083817365,0.3315660934388125,2.624243454701938,0.0972732050141189,0.6345939747312106,0.3315660934388125,-0.763514707401799,0.534719116783902,-0.5325682992306233
| 3,424
|
Autophagy of mitochondrion
| 11
| 33
| 2.374748
| 0.017561
|
Q9NQ11,P21796,Q9Y3D6,Q9NT62,P27544,Q16543,O75143,P04062,Q9NQ88,P50851,P53365
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,3,430,661,103,200,635,368,544,614,90
|
1670,666,1327,635,2001,368,3210,2265,1846,1628,3,103,1962,1635,614,2018,90,966,1006,200,2131,1215,2040,2144,2957,1073,2249,65,544,661,3106,430,2583
|
-0.06252945841594201,0.534719116783902,0.0972732050141189,0.5597916419271479,-0.22540238496379614,0.9037421707307038,-1.1232104786129942,-0.36360068398579487,-0.14357159543690104,-0.035686956378783614,6.325246102229058,2.1039414474895977,-0.1980364707364708,-0.035686956378783614,0.5847945955838018,-0.22540238496379614,2.231181939560065,0.3058415118163126,0.28004145481948706,1.374117034728647,-0.28040536208862893,0.176073624778936,-0.22540238496379614,-0.28040536208862893,-0.8223180083817365,0.25416528674662836,-0.33577561888619256,2.5835449672827635,0.6841215566363612,0.5597916419271479,-0.9712946918324333,0.8311149234361495,-0.5325682992306233
| 3,424
|
Lipid homeostasis
| 9
| 29
| 2.366236
| 0.01797
|
Q9NQ11,Q8WTV0,P28340,Q96CP7,O15118,Q9HCL2,Q5BJF2,P35610,O15260
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,37,383,42,106,49,21,240,339
|
1130,106,432,339,1178,2300,383,3166,240,1053,2120,3375,746,701,21,1360,1213,852,37,42,1073,1382,49,65,660,1723,2986,867,2059
|
0.20218202998275958,2.061178120380909,0.806778655356379,0.9518470676402865,0.176073624778936,-0.3915202453943403,0.8795962071847374,-1.0620808335875023,1.2354253422253956,0.25416528674662836,-0.28040536208862893,-1.697280917985091,0.45907851980090025,0.5095764645830615,3.8718315883611436,0.0972732050141189,0.176073624778936,0.38279132997221815,3.408070428891878,3.197946746840812,0.25416528674662836,0.0972732050141189,3.0230665383232367,2.5835449672827635,0.5597916419271479,-0.06252945841594201,-0.8518859430798013,0.38279132997221815,-0.22540238496379614
| 3,424
|
Abnormal biliary tract morphology
| 10
| 23
| 2.344921
| 0.019031
|
Q96J02,Q9NUN5,Q9UJW0,Q14739,P09601,Q13043,P14174,Q14108,P07602,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,234,497,386,138,265,143,19,115,368
|
501,2790,368,115,138,143,2008,1506,2357,2945,1465,265,19,386,1475,1114,66,1662,234,1993,497,2582,1168
|
0.7087847380791157,-0.7051470219004672,0.9037421707307038,1.975114183919561,1.7124644253307189,1.69026439193255,-0.22540238496379614,0.017745346447724377,-0.41953522517290537,-0.8223180083817365,0.0443366457785035,1.1418385424299435,4.016451430021635,0.8795962071847374,0.0443366457785035,0.22821236301417117,2.5631377808237996,-0.035686956378783614,1.2586797137259673,-0.1980364707364708,0.7333815342116367,-0.5325682992306233,0.20218202998275958
| 3,424
|
Regulation of lymphocyte activation
| 19
| 56
| 2.3389
| 0.019341
|
Q92990,Q96FV9,P14174,P00813,Q9NUQ9,Q16512,P30511,P04083,Q96FZ2,O96028,Q9HCL2,P10644,Q96J02,O15347,Q9BXW9,P78527,P49366,O96005,P30825
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
390,268,143,146,149,155,30,40,301,295,49,53,66,448,478,470,229,226,253
|
1996,1083,448,2495,1617,226,295,566,146,911,40,1400,2407,714,53,3239,2268,1685,143,1251,30,253,695,874,2272,1744,836,916,229,1342,840,470,489,2560,3140,2230,2649,2233,155,1530,3191,3006,1534,2378,2286,390,2925,268,301,1425,66,2323,478,49,2781,149
|
-0.22540238496379614,0.22821236301417117,0.7823779947173779,-0.5041621214531338,-0.035686956378783614,1.2586797137259673,1.0473214180574488,0.6345939747312106,1.6680148523611502,0.3315660934388125,3.2172107186041283,0.07084569120510033,-0.4476465603203489,0.4843631223961893,2.825471169603632,-1.1848376868304877,-0.36360068398579487,-0.06252945841594201,1.69026439193255,0.1498864751122822,3.558497153180639,1.1887466003329457,0.5095764645830615,0.3572158266764965,-0.36360068398579487,-0.08945721189541478,0.38279132997221815,0.3315660934388125,1.2586797137259673,0.0972732050141189,0.38279132997221815,0.7579124526698604,0.7333815342116367,-0.5325682992306233,-1.0316990493048206,-0.33577561888619256,-0.5896824508203791,-0.33577561888619256,1.5560133657211266,0.017745346447724377,-1.0925841770213,-0.8815663376382865,0.017745346447724377,-0.41953522517290537,-0.36360068398579487,0.8795962071847374,-0.7928613254372211,1.1418385424299435,1.0473214180574488,0.07084569120510033,2.5631377808237996,-0.3915202453943403,0.7579124526698604,3.0230665383232367,-0.6761236824753828,1.6680148523611502
| 3,424
|
Metabolism of nucleotides
| 12
| 49
| 2.327246
| 0.019952
|
Q9H773,P30520,Q9Y3Z3,P00491,P17812,P31350,P36639,P04818,P00813,Q9Y3D8,P20839,Q9BW91
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,219,498,566,507,417,170,449,146,283,88,291
|
2533,1788,669,2349,566,992,1331,146,912,449,1449,2004,1684,1793,507,88,1296,1573,2011,1508,1908,1576,739,219,1456,417,1632,1137,696,170,1191,1966,2639,2073,1811,573,1352,1205,1864,291,2247,1074,0,1031,1322,3363,1391,283,498
|
-0.5325682992306233,-0.11647099443820123,0.534719116783902,-0.41953522517290537,0.6345939747312106,0.28004145481948706,0.0972732050141189,1.6680148523611502,0.3315660934388125,0.7823779947173779,0.0443366457785035,-0.22540238496379614,-0.06252945841594201,-0.11647099443820123,0.7087847380791157,2.2732523402364393,0.12361989908791096,-0.008928939691278415,-0.22540238496379614,0.017745346447724377,-0.17075981630557494,-0.008928939691278415,0.45907851980090025,1.2818779400411169,0.0443366457785035,0.8311149234361495,-0.035686956378783614,0.20218202998275958,0.5095764645830615,1.4881976158068801,0.176073624778936,-0.1980364707364708,-0.5896824508203791,-0.25285839803484295,-0.11647099443820123,0.6345939747312106,0.0972732050141189,0.176073624778936,-0.14357159543690104,1.0710393665641098,-0.33577561888619256,0.25416528674662836,8.407992880482578,0.28004145481948706,0.12361989908791096,-1.5983998609621628,0.0972732050141189,1.0946979225093583,0.7333815342116367
| 3,424
|
Metalloprotease
| 9
| 40
| 2.323818
| 0.020135
|
O75844,P55786,O43847,P52888,Q9BYT8,P42892,P20839,Q5JRX3,Q9UIQ6
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
64,163,212,10,379,92,88,279,29
|
1325,949,688,212,3185,64,911,1684,737,1185,88,2222,3357,2944,92,1305,10,163,1465,1416,1812,2182,279,1111,1926,850,1874,3233,377,2924,723,2983,1022,2145,379,1386,1946,767,29,2584
|
0.0972732050141189,0.3058415118163126,0.5095764645830615,1.3050204064717228,-1.0925841770213,2.5835449672827635,0.3315660934388125,-0.06252945841594201,0.45907851980090025,0.176073624778936,2.2732523402364393,-0.33577561888619256,-1.565741227335299,-0.8223180083817365,2.210083029251862,0.12361989908791096,4.663727626155535,1.5108548870512621,0.0443366457785035,0.07084569120510033,-0.11647099443820123,-0.3080441426423994,1.0946979225093583,0.22821236301417117,-0.17075981630557494,0.38279132997221815,-0.14357159543690104,-1.1539611641322176,0.9037421707307038,-0.7928613254372211,0.4843631223961893,-0.8518859430798013,0.28004145481948706,-0.28040536208862893,0.9037421707307038,0.0972732050141189,-0.17075981630557494,0.45907851980090025,3.614405798250022,-0.5325682992306233
| 3,424
|
Actin polymerization or depolymerization
| 15
| 52
| 2.319696
| 0.020357
|
O95429,Q12768,Q9NYB9,Q9NYL9,Q96F07,P58546,Q13045,P62993,Q9UQB8,Q9NUQ9,Q14019,Q6ZU35,P50552,P35080,P07737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,324,429,235,425,385,421,353,17,149,538,24,536,399,435
|
1670,2589,2401,952,1567,2497,1177,96,435,1452,738,399,1964,1691,1692,1140,2307,1096,536,1968,2506,385,1856,1195,353,2025,2469,1003,324,1977,421,2422,538,1006,2808,24,577,1218,1934,425,1375,149,429,235,2205,1723,1078,17,1609,1665,686,1128
|
-0.06252945841594201,-0.5610747366914889,-0.4476465603203489,0.3058415118163126,-0.008928939691278415,-0.5041621214531338,0.176073624778936,2.1889413177819854,0.806778655356379,0.0443366457785035,0.45907851980090025,0.8553872817591445,-0.1980364707364708,-0.06252945841594201,-0.06252945841594201,0.20218202998275958,-0.3915202453943403,0.22821236301417117,0.6841215566363612,-0.1980364707364708,-0.5041621214531338,0.8795962071847374,-0.14357159543690104,0.176073624778936,0.927825637672481,-0.22540238496379614,-0.4758552031128107,0.28004145481948706,0.9997056275167767,-0.1980364707364708,0.8311149234361495,-0.4476465603203489,0.6841215566363612,0.28004145481948706,-0.7051470219004672,3.8171415688003916,0.6345939747312106,0.176073624778936,-0.17075981630557494,0.8311149234361495,0.0972732050141189,1.6680148523611502,0.8311149234361495,1.2586797137259673,-0.3080441426423994,-0.06252945841594201,0.25416528674662836,4.194804424150486,-0.008928939691278415,-0.035686956378783614,0.534719116783902,0.22821236301417117
| 3,424
|
Mitotic g1 phase and g1 s transition
| 29
| 79
| 2.31969
| 0.020358
|
Q99436,O00231,P49721,P30154,P61289,P60900,Q07864,Q9Y619,Q9UL46,P63151,Q92530,P28072,P31350,P28070,O75832,P25788,P25205,P20618,P31751,O43242,P30153,P28074,P11802,P04818,P06493,Q9NR33,P15927,P00374,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,264,645,160,677,166,563,676,172,43,417,45,415,416,176,55,308,689,320,77,450,449,589,233,369,109,616
|
499,1896,949,1837,689,2899,2452,415,109,912,449,589,1134,3291,450,798,2006,369,1627,55,1092,176,1453,1048,416,1849,1252,1337,45,43,77,320,264,417,695,308,1457,1577,1049,1509,2071,915,1582,877,1190,1852,918,8,1460,1305,1638,2553,160,645,1347,1348,1518,676,842,1700,616,677,2178,1146,2599,1206,971,1470,2237,1878,172,128,1370,233,1434,2672,563,1556,166
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,-0.7928613254372211,-0.4758552031128107,0.8311149234361495,2.039729696998139,0.3315660934388125,0.7823779947173779,0.6097285261007889,0.20218202998275958,-1.3096322187119562,0.7823779947173779,0.4082932133836793,-0.22540238496379614,0.9037421707307038,-0.035686956378783614,2.7855222848906425,0.22821236301417117,1.465487864832413,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.1498864751122822,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,0.9997056275167767,1.1418385424299435,0.8311149234361495,0.5095764645830615,1.0235436493047718,0.0443366457785035,-0.008928939691278415,0.25416528674662836,0.017745346447724377,-0.25285839803484295,0.3315660934388125,-0.008928939691278415,0.3572158266764965,0.176073624778936,-0.14357159543690104,0.3315660934388125,5.197689907839026,0.0443366457785035,0.12361989908791096,-0.035686956378783614,-0.5325682992306233,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.534719116783902,0.38279132997221815,-0.06252945841594201,0.5847945955838018,0.534719116783902,-0.3080441426423994,0.20218202998275958,-0.5610747366914889,0.176073624778936,0.3058415118163126,0.0443366457785035,-0.33577561888619256,-0.14357159543690104,1.4881976158068801,1.8665043911430075,0.0972732050141189,1.2586797137259673,0.07084569120510033,-0.5896824508203791,0.6593914757616174,0.017745346447724377,1.5108548870512621
| 3,424
|
Sphingolipid metabolism
| 11
| 30
| 2.312834
| 0.020732
|
Q8NBJ7,P27544,Q06136,P10619,O15270,Q96G23,P07602,O95470,Q9NZD2,Q13510,P06280
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
165,103,108,139,204,206,115,239,347,91,153
|
2255,829,204,501,2716,239,368,153,548,115,2792,139,2008,639,777,2010,103,965,108,91,2316,165,206,2289,2932,2097,347,1993,3183,867
|
-0.36360068398579487,0.38279132997221815,1.3511395792365377,0.7087847380791157,-0.6472058630830041,1.2354253422253956,0.9037421707307038,1.5560133657211266,0.6593914757616174,1.975114183919561,-0.7051470219004672,1.7124644253307189,-0.22540238496379614,0.5597916419271479,0.4337220787410696,-0.22540238496379614,2.1039414474895977,0.3058415118163126,2.061178120380909,2.231181939560065,-0.3915202453943403,1.5108548870512621,1.3511395792365377,-0.36360068398579487,-0.7928613254372211,-0.25285839803484295,0.9518470676402865,-0.1980364707364708,-1.0620808335875023,0.38279132997221815
| 3,424
|
Negative regulation of cell activation
| 9
| 17
| 2.312635
| 0.020743
|
Q96J02,Q92990,O15347,Q96FV9,P09601,P04083,P10644,Q16512,P30511
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,390,448,268,138,40,53,155,30
|
448,40,714,138,53,30,874,836,1342,489,1003,2649,155,390,268,1425,66
|
0.7823779947173779,3.2172107186041283,0.4843631223961893,1.7124644253307189,2.825471169603632,3.558497153180639,0.3572158266764965,0.38279132997221815,0.0972732050141189,0.7333815342116367,0.28004145481948706,-0.5896824508203791,1.5560133657211266,0.8795962071847374,1.1418385424299435,0.07084569120510033,2.5631377808237996
| 3,424
|
Sensory perception
| 6
| 42
| 2.311933
| 0.020781
|
O95677,O43924,Q14108,O60443,P50897,P36383
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,7,19,20,26,187
|
1445,7,1172,20,1567,2497,991,2865,1676,129,3111,2792,2942,1093,1910,1578,187,836,2358,26,2874,1142,1810,1701,19,422,1361,1212,1013,3079,1367,3154,1022,3393,461,1552,2987,2748,208,1037,2292,1669
|
0.0443366457785035,5.246628713778516,0.176073624778936,3.9081517315608365,-0.008928939691278415,-0.5041621214531338,0.28004145481948706,-0.763514707401799,-0.06252945841594201,1.82273284893905,-1.001437451234241,-0.7051470219004672,-0.8223180083817365,0.22821236301417117,-0.17075981630557494,-0.008928939691278415,1.4199095256546266,0.38279132997221815,-0.41953522517290537,3.743824687447206,-0.763514707401799,0.20218202998275958,-0.11647099443820123,-0.06252945841594201,4.016451430021635,0.8311149234361495,0.0972732050141189,0.176073624778936,0.28004145481948706,-0.9412694483017089,0.0972732050141189,-1.0316990493048206,0.28004145481948706,-1.9335510119031862,0.7823779947173779,0.017745346447724377,-0.8518859430798013,-0.6472058630830041,1.3511395792365377,0.28004145481948706,-0.36360068398579487,-0.035686956378783614
| 3,424
|
Cytoprotection by hmox1
| 22
| 68
| 2.295916
| 0.021681
|
Q99436,O00231,P49721,P09601,P61289,P60900,P30519,O43819,Q9UL46,Q92530,P28072,P25788,O75832,P40763,P28070,P20618,P28074,Q8N8Q8,Q86X55,Q14997,P30043,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,138,645,160,34,670,563,172,43,416,415,673,45,55,77,334,621,355,246,616
|
499,1896,2626,949,2446,1837,689,670,1085,415,1675,1679,138,2680,1792,2542,2219,1627,1628,55,833,1453,1048,416,1849,1337,45,43,77,246,34,1963,2071,673,2836,1582,877,918,8,1305,1636,1638,160,645,1347,1348,1518,842,2799,1003,616,2178,1146,1206,1704,355,1470,1148,621,334,3080,172,2288,2436,128,1370,563,1556
|
0.7087847380791157,-0.17075981630557494,-0.5896824508203791,0.3058415118163126,-0.4758552031128107,-0.14357159543690104,0.5095764645830615,0.534719116783902,0.22821236301417117,0.8311149234361495,-0.06252945841594201,-0.06252945841594201,1.7124644253307189,-0.6183924757333895,-0.11647099443820123,-0.5325682992306233,-0.33577561888619256,-0.035686956378783614,-0.035686956378783614,2.7855222848906425,0.38279132997221815,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,1.212114435826368,3.4458619829507984,-0.1980364707364708,-0.25285839803484295,0.534719116783902,-0.7342769881754115,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,-0.7051470219004672,0.28004145481948706,0.5847945955838018,-0.3080441426423994,0.20218202998275958,0.176073624778936,-0.06252945841594201,0.927825637672481,0.0443366457785035,0.20218202998275958,0.5847945955838018,0.9758069147141267,-0.9412694483017089,1.4881976158068801,-0.36360068398579487,-0.4476465603203489,1.8665043911430075,0.0972732050141189,0.6593914757616174,0.017745346447724377
| 3,424
|
Peptidase complex
| 21
| 62
| 2.289617
| 0.022044
|
Q99436,O00231,P49721,O43292,P61289,Q9Y6J9,Q05086,P60900,Q9UL46,O43396,Q92530,P28072,P25788,O75832,P28070,P20618,P28074,P67812,Q14997,P54727,Q06323
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,499,8,634,645,22,401,160,563,667,172,43,416,415,45,55,77,220,355,615,616
|
499,1896,949,1837,689,634,667,1327,3402,415,2455,1847,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1052,615,1638,2552,160,2465,645,1347,1348,1518,220,401,616,2178,355,1708,1470,1528,2032,1358,2039,172,815,2656,2048,128,1370,3264,563,1556,768,2584,1612,22
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.5597916419271479,0.534719116783902,0.0972732050141189,-2.2858818540375703,0.8311149234361495,-0.4758552031128107,-0.14357159543690104,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,0.25416528674662836,0.5847945955838018,-0.035686956378783614,-0.5325682992306233,1.5334600233386158,-0.4758552031128107,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,1.2818779400411169,0.8553872817591445,0.5847945955838018,-0.3080441426423994,0.927825637672481,-0.06252945841594201,0.0443366457785035,0.017745346447724377,-0.22540238496379614,0.0972732050141189,-0.22540238496379614,1.4881976158068801,0.4082932133836793,-0.5896824508203791,-0.22540238496379614,1.8665043911430075,0.0972732050141189,-1.215841528185196,0.6593914757616174,0.017745346447724377,0.45907851980090025,-0.5325682992306233,-0.008928939691278415,3.8536296787345377
| 3,424
|
Duplication involving bones of the feet
| 8
| 25
| 2.286931
| 0.0222
|
Q96J42,O43924,O96028,Q15125,Q2M1P5,O75845,Q8NCM8,O75665
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
99,7,295,209,183,89,157,95
|
3225,7,95,89,2403,1733,295,1906,1800,2225,1465,2280,386,209,183,3077,157,1767,2385,99,2245,2393,1663,1284,665
|
-1.1539611641322176,5.246628713778516,2.1889413177819854,2.231181939560065,-0.4476465603203489,-0.08945721189541478,1.0473214180574488,-0.17075981630557494,-0.11647099443820123,-0.33577561888619256,0.0443366457785035,-0.36360068398579487,0.8795962071847374,1.3281074939758217,1.442725285577121,-0.9412694483017089,1.5560133657211266,-0.08945721189541478,-0.41953522517290537,2.167756556317077,-0.33577561888619256,-0.41953522517290537,-0.035686956378783614,0.1498864751122822,0.5597916419271479
| 3,424
|
Neddylation
| 33
| 73
| 2.272085
| 0.023081
|
Q99436,P61081,O00231,P49721,P61962,Q8NEZ5,P61289,Q9UBW8,Q9BTE7,P60900,Q9UL46,Q92530,P28072,P49720,P25788,O75832,P28070,Q13098,Q9BW61,P20618,O43242,Q9UNS2,O00487,P28074,Q9NX08,P63208,O60826,P48556,Q99627,Q8TBC4,Q14997,Q92905,Q06323
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,744,499,8,880,541,645,943,426,160,563,172,43,918,416,415,45,803,706,55,689,864,949,77,346,842,464,877,361,892,355,377,616
|
499,1896,949,1837,689,464,415,955,1627,55,1453,1048,416,1849,1337,45,43,77,2071,1582,877,918,8,1305,1638,160,744,1099,645,880,2910,1347,1348,1518,842,616,803,2178,1146,1523,1206,1415,1704,1978,1593,355,1470,2562,2081,1313,1926,1363,1216,541,892,172,2381,377,1541,128,1370,361,1717,426,706,2965,346,943,563,1556,864,1238,1444
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.7579124526698604,0.8311149234361495,0.3058415118163126,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.25285839803484295,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.45907851980090025,0.22821236301417117,0.5597916419271479,0.3572158266764965,-0.7928613254372211,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.5847945955838018,0.4082932133836793,-0.3080441426423994,0.20218202998275958,0.017745346447724377,0.176073624778936,0.07084569120510033,-0.06252945841594201,-0.1980364707364708,-0.008928939691278415,0.927825637672481,0.0443366457785035,-0.5325682992306233,-0.25285839803484295,0.12361989908791096,-0.17075981630557494,0.0972732050141189,0.176073624778936,0.6841215566363612,0.3572158266764965,1.4881976158068801,-0.41953522517290537,0.9037421707307038,0.017745346447724377,1.8665043911430075,0.0972732050141189,0.927825637672481,-0.06252945841594201,0.8311149234361495,0.5095764645830615,-0.8223180083817365,0.9518470676402865,0.3315660934388125,0.6593914757616174,0.017745346447724377,0.38279132997221815,0.176073624778936,0.07084569120510033
| 3,424
|
Positive regulation of autophagy
| 6
| 29
| 2.271517
| 0.023116
|
P21796,P27544,P09601,O15270,P19474,Q9BXS4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,103,138,204,121,255
|
1897,2257,829,204,2000,3062,1568,2265,2867,714,138,1846,121,3,1093,103,1635,571,1053,746,1260,1474,1315,2133,2144,255,820,2860,315
|
-0.17075981630557494,-0.36360068398579487,0.38279132997221815,1.3511395792365377,-0.22540238496379614,-0.9412694483017089,-0.008928939691278415,-0.36360068398579487,-0.763514707401799,0.4843631223961893,1.7124644253307189,-0.14357159543690104,1.9100875739304093,6.325246102229058,0.22821236301417117,2.1039414474895977,-0.035686956378783614,0.6345939747312106,0.25416528674662836,0.45907851980090025,0.1498864751122822,0.0443366457785035,0.12361989908791096,-0.28040536208862893,-0.28040536208862893,1.1887466003329457,0.4082932133836793,-0.7342769881754115,1.0235436493047718
| 3,424
|
Selective autophagy
| 7
| 32
| 2.27051
| 0.023177
|
P04350,P21796,P68371,Q9BVA1,O94826,Q8N4H5,Q9NS69
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
218,3,322,269,136,404,60
|
2062,1173,136,2001,2216,218,1180,567,2217,1628,3,1585,1053,2552,745,2121,2799,322,1410,2125,439,1524,1472,930,404,2484,3220,2144,657,269,60,1081
|
-0.25285839803484295,0.176073624778936,1.7346152657608775,-0.22540238496379614,-0.33577561888619256,1.2818779400411169,0.176073624778936,0.6345939747312106,-0.33577561888619256,-0.035686956378783614,6.325246102229058,-0.008928939691278415,0.25416528674662836,-0.5325682992306233,0.45907851980090025,-0.28040536208862893,-0.7051470219004672,0.9997056275167767,0.07084569120510033,-0.28040536208862893,0.806778655356379,0.017745346447724377,0.0443366457785035,0.3315660934388125,0.8553872817591445,-0.4758552031128107,-1.1232104786129942,-0.28040536208862893,0.5597916419271479,1.1418385424299435,2.624243454701938,0.25416528674662836
| 3,424
|
Negative regulation of response to external stimulus
| 15
| 51
| 2.265789
| 0.023464
|
Q9H000,Q96J02,Q9Y3Z3,Q16539,P78540,P28070,Q96G23,P80303,P14174,P00813,O43657,P19474,P04062,Q9UMX5,P30511
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
427,66,498,455,489,45,206,15,143,146,238,121,368,190,30
|
1729,951,238,1086,1177,146,3024,368,1400,2407,143,2167,121,1453,45,996,30,874,1910,2546,674,1342,2276,3034,1461,489,15,2802,1003,2078,1101,846,455,1010,650,2378,1713,2567,1767,206,66,524,855,427,2151,3362,730,190,498,1167,2494
|
-0.08945721189541478,0.3058415118163126,1.2354253422253956,0.22821236301417117,0.176073624778936,1.6680148523611502,-0.9113604219611866,0.9037421707307038,0.07084569120510033,-0.4476465603203489,1.69026439193255,-0.3080441426423994,1.9100875739304093,0.0443366457785035,3.081664317034927,0.28004145481948706,3.558497153180639,0.3572158266764965,-0.17075981630557494,-0.5325682992306233,0.534719116783902,0.0972732050141189,-0.36360068398579487,-0.9113604219611866,0.0443366457785035,0.7333815342116367,4.370570465939998,-0.7051470219004672,0.28004145481948706,-0.25285839803484295,0.22821236301417117,0.38279132997221815,0.7823779947173779,0.28004145481948706,0.5597916419271479,-0.41953522517290537,-0.06252945841594201,-0.5325682992306233,-0.08945721189541478,1.3511395792365377,2.5631377808237996,0.7087847380791157,0.38279132997221815,0.8311149234361495,-0.28040536208862893,-1.5983998609621628,0.4843631223961893,1.4199095256546266,0.7333815342116367,0.20218202998275958,-0.4758552031128107
| 3,424
|
Protein transmembrane transport
| 9
| 26
| 2.262543
| 0.023664
|
O94826,O60830,Q15629,Q99595,O95831,Q9Y584,P31751,O14925,Q9NS69
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
136,12,144,16,331,250,308,305,60
|
305,1291,12,636,1998,136,331,2216,3239,308,1804,3035,1974,2766,2842,1472,144,1865,1929,1367,2855,16,2665,60,412,250
|
1.0235436493047718,0.12361989908791096,4.629595354354387,0.5597916419271479,-0.22540238496379614,1.7346152657608775,0.9758069147141267,-0.33577561888619256,-1.1848376868304877,1.0235436493047718,-0.11647099443820123,-0.9113604219611866,-0.1980364707364708,-0.6761236824753828,-0.7342769881754115,0.0443366457785035,1.69026439193255,-0.14357159543690104,-0.17075981630557494,0.0972732050141189,-0.7342769881754115,4.2830041272536015,-0.5896824508203791,2.624243454701938,0.8553872817591445,1.212114435826368
| 3,424
|
Autophagosome
| 9
| 30
| 2.258277
| 0.023928
|
Q9NQ11,O95721,O15321,Q96GC9,P56962,Q9Y3E7,Q8WUX9,P19474,Q969Q5
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
65,252,75,47,147,348,281,121,254
|
75,396,1957,252,2866,2217,2268,1402,121,2012,2464,147,966,281,254,932,3081,47,1937,1230,1119,65,1435,1437,685,1125,2860,348,3336,1562
|
2.3776962925175247,0.8553872817591445,-0.1980364707364708,1.1887466003329457,-0.763514707401799,-0.33577561888619256,-0.36360068398579487,0.07084569120510033,1.9100875739304093,-0.22540238496379614,-0.4758552031128107,1.6680148523611502,0.3058415118163126,1.0946979225093583,1.1887466003329457,0.3315660934388125,-0.9412694483017089,3.0621659370708794,-0.17075981630557494,0.176073624778936,0.22821236301417117,2.5835449672827635,0.07084569120510033,0.07084569120510033,0.534719116783902,0.22821236301417117,-0.7342769881754115,0.9518470676402865,-1.4365640802810167,0.017745346447724377
| 3,424
|
Organophosphate ester transport
| 6
| 31
| 2.252732
| 0.024276
|
Q8WTV0,P41440,Q9BSK2,Q96GC9,Q14108,O00400
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
37,110,141,47,19,123
|
123,484,2830,2265,1332,168,1846,2108,2010,2169,1963,110,963,2120,1003,3140,19,1314,1763,3301,598,37,47,725,141,1319,446,2780,347,3183,867
|
1.8883193828815668,0.7333815342116367,-0.7342769881754115,-0.36360068398579487,0.0972732050141189,1.4881976158068801,-0.14357159543690104,-0.28040536208862893,-0.22540238496379614,-0.3080441426423994,-0.1980364707364708,2.039729696998139,0.3058415118163126,-0.28040536208862893,0.28004145481948706,-1.0316990493048206,4.016451430021635,0.12361989908791096,-0.08945721189541478,-1.3096322187119562,0.6097285261007889,3.408070428891878,3.0621659370708794,0.4843631223961893,1.7124644253307189,0.12361989908791096,0.806778655356379,-0.6761236824753828,0.9518470676402865,-1.0620808335875023,0.38279132997221815
| 3,424
|
serine protease
| 7
| 21
| 2.250891
| 0.024392
|
O14773,Q9H3G5,Q8N2K0,Q9HB40,P10619,P42785,P67812
|
Functions
|
Panther Protein class
|
panther_protein_class
|
162,98,41,11,139,14,220
|
162,1327,1623,139,1738,2410,1797,2357,14,1802,220,474,274,1529,3418,1268,41,2192,2249,98,11
|
1.5108548870512621,0.0972732050141189,-0.035686956378783614,1.7124644253307189,-0.08945721189541478,-0.4476465603203489,-0.11647099443820123,-0.41953522517290537,4.388008865230443,-0.11647099443820123,1.2818779400411169,0.7579124526698604,1.11829750855662,0.017745346447724377,-3.006727350510937,0.1498864751122822,3.2172107186041283,-0.3080441426423994,-0.33577561888619256,2.1889413177819854,4.663727626155535
| 3,424
|
Macromolecule transmembrane transporter activity
| 6
| 13
| 2.242975
| 0.024898
|
O94826,O60830,Q99595,Q9Y584,O14925,Q9NS69
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
136,12,16,250,305,60
|
305,12,136,2216,1804,1406,2766,2842,1472,16,60,412,250
|
1.0235436493047718,4.629595354354387,1.7346152657608775,-0.33577561888619256,-0.11647099443820123,0.07084569120510033,-0.6761236824753828,-0.7342769881754115,0.0443366457785035,4.2830041272536015,2.624243454701938,0.8553872817591445,1.212114435826368
| 3,424
|
Regulation of mrna stability by proteins that bind au rich elements
| 23
| 67
| 2.240109
| 0.025084
|
Q99436,O00231,P49721,Q9NPI6,P61289,Q9NQT4,P60900,Q9UL46,Q92530,P28072,Q92973,P25788,O75832,P28070,P20618,O43242,Q16539,P28074,Q01105,P39687,Q14997,Q06323,Q92945
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,499,8,543,645,428,160,563,172,43,300,416,415,45,55,689,455,77,332,468,355,616,523
|
499,1896,949,1837,1038,689,415,2500,2455,2217,736,1451,1627,55,1453,1048,416,1849,1337,45,43,77,695,961,2356,2071,468,1582,877,918,8,1305,1638,160,645,1347,1348,1518,922,332,1308,1003,2768,616,2178,1705,970,355,1470,2687,2474,455,1530,172,523,300,2483,128,1370,2440,543,428,2781,563,1556,1036,1127
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.25416528674662836,0.5095764645830615,0.8311149234361495,-0.5041621214531338,-0.4758552031128107,-0.33577561888619256,0.45907851980090025,0.0443366457785035,-0.035686956378783614,2.7855222848906425,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,0.5095764645830615,0.3058415118163126,-0.41953522517290537,-0.25285839803484295,0.7579124526698604,-0.008928939691278415,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.3315660934388125,0.9758069147141267,0.12361989908791096,0.28004145481948706,-0.6761236824753828,0.5847945955838018,-0.3080441426423994,-0.06252945841594201,0.3058415118163126,0.927825637672481,0.0443366457785035,-0.6183924757333895,-0.4758552031128107,0.7823779947173779,0.017745346447724377,1.4881976158068801,0.7087847380791157,1.0473214180574488,-0.4758552031128107,1.8665043911430075,0.0972732050141189,-0.4476465603203489,0.6841215566363612,0.8311149234361495,-0.6761236824753828,0.6593914757616174,0.017745346447724377,0.28004145481948706,0.22821236301417117
| 3,424
|
Negative regulation of lymphocyte activation
| 8
| 15
| 2.225944
| 0.026018
|
Q96J02,Q92990,O15347,Q96FV9,P04083,P10644,Q16512,P30511
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,390,448,268,40,53,155,30
|
448,40,714,53,30,874,836,1342,489,2649,155,390,268,1425,66
|
0.7823779947173779,3.2172107186041283,0.4843631223961893,2.825471169603632,3.558497153180639,0.3572158266764965,0.38279132997221815,0.0972732050141189,0.7333815342116367,-0.5896824508203791,1.5560133657211266,0.8795962071847374,1.1418385424299435,0.07084569120510033,2.5631377808237996
| 3,424
|
Glycosyl compound metabolic process
| 6
| 28
| 2.223962
| 0.026151
|
Q13126,O60725,P00813,Q9BTY2,P06280,Q9NUJ1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,142,146,158,153,62
|
2533,2258,669,1565,142,566,992,146,368,691,912,153,1449,2004,2409,2218,1450,2011,1632,170,1191,2073,3171,573,4,158,62,3373
|
-0.5325682992306233,-0.36360068398579487,0.534719116783902,-0.008928939691278415,1.69026439193255,0.6345939747312106,0.28004145481948706,1.6680148523611502,0.9037421707307038,0.5095764645830615,0.3315660934388125,1.5560133657211266,0.0443366457785035,-0.22540238496379614,-0.4476465603203489,-0.33577561888619256,0.0443366457785035,-0.22540238496379614,-0.035686956378783614,1.4881976158068801,0.176073624778936,-0.25285839803484295,-1.0620808335875023,0.6345939747312106,6.295154260110702,1.5560133657211266,2.6039134556484878,-1.6641677130009633
| 3,424
|
Endoplasmic reticulum golgi intermediate compartment membrane
| 10
| 32
| 2.222395
| 0.026257
|
Q5BJH7,P24390,Q8N511,Q9Y282,Q9BZE9,Q12907,Q96GC9,P56962,Q03519,O15260
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
288,33,194,100,135,453,47,147,182,339
|
712,339,1132,2756,1329,33,2681,510,1804,2873,1000,147,2466,844,182,2912,699,453,2510,2772,928,288,194,1424,47,2324,2615,135,2201,100,1323,1441
|
0.4843631223961893,0.9518470676402865,0.20218202998275958,-0.6761236824753828,0.0972732050141189,3.4458619829507984,-0.6183924757333895,0.7087847380791157,-0.11647099443820123,-0.763514707401799,0.28004145481948706,1.6680148523611502,-0.4758552031128107,0.38279132997221815,1.442725285577121,-0.7928613254372211,0.5095764645830615,0.7823779947173779,-0.5041621214531338,-0.6761236824753828,0.3315660934388125,1.0710393665641098,1.3970402287838317,0.07084569120510033,3.0621659370708794,-0.3915202453943403,-0.5610747366914889,1.7567172231726083,-0.3080441426423994,2.167756556317077,0.12361989908791096,0.07084569120510033
| 3,424
|
Protein transmembrane transporter activity
| 6
| 12
| 2.218519
| 0.026519
|
O94826,O60830,Q99595,Q9Y584,O14925,Q9NS69
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
136,12,16,250,305,60
|
305,12,136,2216,1804,2766,2842,1472,16,60,412,250
|
1.0235436493047718,4.629595354354387,1.7346152657608775,-0.33577561888619256,-0.11647099443820123,-0.6761236824753828,-0.7342769881754115,0.0443366457785035,4.2830041272536015,2.624243454701938,0.8553872817591445,1.212114435826368
| 3,424
|
Plasma membrane organization
| 7
| 33
| 2.21607
| 0.026687
|
Q96CP7,P41440,Q96GC9,Q9UQB8,Q9Y3E7,Q8WUX9,P31751
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
42,110,47,17,348,281,308
|
1445,396,1844,3267,2299,695,308,1338,110,2172,511,2469,1003,3038,1920,1862,1314,2135,281,2192,42,47,1119,2859,1437,1893,2968,17,1125,1287,2860,348,1128
|
0.0443366457785035,0.8553872817591445,-0.14357159543690104,-1.2469741986696485,-0.3915202453943403,0.5095764645830615,1.0235436493047718,0.0972732050141189,2.039729696998139,-0.3080441426423994,0.7087847380791157,-0.4758552031128107,0.28004145481948706,-0.9113604219611866,-0.17075981630557494,-0.14357159543690104,0.12361989908791096,-0.28040536208862893,1.0946979225093583,-0.3080441426423994,3.197946746840812,3.0621659370708794,0.22821236301417117,-0.7342769881754115,0.07084569120510033,-0.14357159543690104,-0.8223180083817365,4.194804424150486,0.22821236301417117,0.1498864751122822,-0.7342769881754115,0.9518470676402865,0.22821236301417117
| 3,424
|
Inorganic anion transport
| 7
| 27
| 2.210279
| 0.027086
|
Q9UHG3,P21796,O43681,Q9C0H2,P08183,P45880,O15439
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,3,501,303,168,13,484
|
989,484,501,168,3027,3,1962,1963,13,512,1969,2276,2684,2367,1646,1314,2850,3301,1275,1376,303,1117,862,2,1724,2711,1242
|
0.28004145481948706,0.7333815342116367,0.7087847380791157,1.4881976158068801,-0.9113604219611866,6.325246102229058,-0.1980364707364708,-0.1980364707364708,4.561049497959283,0.7087847380791157,-0.1980364707364708,-0.36360068398579487,-0.6183924757333895,-0.41953522517290537,-0.035686956378783614,0.12361989908791096,-0.7342769881754115,-1.3096322187119562,0.1498864751122822,0.0972732050141189,1.0473214180574488,0.22821236301417117,0.38279132997221815,6.870655213788565,-0.06252945841594201,-0.6183924757333895,0.176073624778936
| 3,424
|
Alcohol biosynthetic process
| 11
| 40
| 2.195589
| 0.028121
|
Q16850,Q14739,O15270,Q15392,P04062,P00374,Q15125,Q15800,O75845,P35270,Q13510
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,386,204,44,368,109,209,84,89,58,91
|
2587,829,204,1041,89,2345,2539,109,3209,368,1570,1683,610,1960,2300,1094,58,3031,3032,436,1193,1053,592,2950,2802,746,91,1644,386,209,1355,44,2514,84,3146,131,2144,1280,2932,1663
|
-0.5610747366914889,0.38279132997221815,1.3511395792365377,0.25416528674662836,2.231181939560065,-0.41953522517290537,-0.5325682992306233,2.039729696998139,-1.1232104786129942,0.9037421707307038,-0.008928939691278415,-0.06252945841594201,0.5847945955838018,-0.1980364707364708,-0.3915202453943403,0.22821236301417117,2.7253232892615076,-0.9113604219611866,-0.9113604219611866,0.806778655356379,0.176073624778936,0.25416528674662836,0.6097285261007889,-0.8223180083817365,-0.7051470219004672,0.45907851980090025,2.231181939560065,-0.035686956378783614,0.8795962071847374,1.3281074939758217,0.0972732050141189,3.1011287111609,-0.5041621214531338,2.2942243165759035,-1.0316990493048206,1.82273284893905,-0.28040536208862893,0.1498864751122822,-0.7928613254372211,-0.035686956378783614
| 3,424
|
Negative regulation of protein polymerization
| 9
| 29
| 2.194812
| 0.028177
|
P04350,Q9NYL9,P58546,Q13045,P45880,Q9NUQ9,Q6ZU35,P35080,P07737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
218,235,385,421,13,149,24,399,435
|
2589,1177,218,435,1091,738,399,1964,1691,1692,13,2307,1096,1968,385,2469,514,1003,1977,421,2422,3318,784,24,1375,1072,149,235,2205
|
-0.5610747366914889,0.176073624778936,1.2818779400411169,0.806778655356379,0.22821236301417117,0.45907851980090025,0.8553872817591445,-0.1980364707364708,-0.06252945841594201,-0.06252945841594201,4.561049497959283,-0.3915202453943403,0.22821236301417117,-0.1980364707364708,0.8795962071847374,-0.4758552031128107,0.7087847380791157,0.28004145481948706,-0.1980364707364708,0.8311149234361495,-0.4476465603203489,-1.3728244416731277,0.4337220787410696,3.8171415688003916,0.0972732050141189,0.25416528674662836,1.6680148523611502,1.2586797137259673,-0.3080441426423994
| 3,424
|
Endosome organization
| 16
| 31
| 2.178295
| 0.029384
|
Q9P253,Q12768,Q9H267,P51790,Q8IYI6,Q92783,O75165,Q99816,Q14108,Q2M389,O43633,Q8WUX9,Q9Y3E7,P53990,Q9BRG1,O43752
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
685,324,763,512,171,111,607,726,19,179,396,281,348,717,222,531
|
396,531,1328,607,3385,2464,512,717,1098,324,19,2370,179,1360,171,1219,281,111,3082,726,222,1071,763,764,1119,1437,685,2824,1166,1125,348
|
0.8553872817591445,0.6841215566363612,0.0972732050141189,0.5847945955838018,-1.7975625050538029,-0.4758552031128107,0.7087847380791157,0.4843631223961893,0.22821236301417117,0.9997056275167767,4.016451430021635,-0.41953522517290537,1.465487864832413,0.0972732050141189,1.4881976158068801,0.176073624778936,1.0946979225093583,2.039729696998139,-0.9412694483017089,0.4843631223961893,1.2818779400411169,0.25416528674662836,0.45907851980090025,0.45907851980090025,0.22821236301417117,0.07084569120510033,0.534719116783902,-0.7051470219004672,0.20218202998275958,0.22821236301417117,0.9518470676402865
| 3,424
|
Lytic vacuole organization
| 9
| 29
| 2.176724
| 0.029501
|
O14773,Q12768,Q8N511,P54802,O75503,P11117,Q14108,Q9Y3E7,P50897
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
162,324,194,259,73,169,19,348,26
|
1996,162,73,1957,1042,368,2792,993,169,1140,26,2464,259,1696,324,19,1360,194,3081,3082,855,899,3314,2744,2859,1552,685,1125,348
|
-0.22540238496379614,1.5108548870512621,2.4398700711321197,-0.1980364707364708,0.25416528674662836,0.9037421707307038,-0.7051470219004672,0.28004145481948706,1.4881976158068801,0.20218202998275958,3.743824687447206,-0.4758552031128107,1.165321436994088,-0.06252945841594201,0.9997056275167767,4.016451430021635,0.0972732050141189,1.3970402287838317,-0.9412694483017089,-0.9412694483017089,0.38279132997221815,0.3572158266764965,-1.3411607415134839,-0.6472058630830041,-0.7342769881754115,0.017745346447724377,0.534719116783902,0.22821236301417117,0.9518470676402865
| 3,424
|
Subsets and Splits
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