term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Autophagy
| 18
| 49
| 2.169526
| 0.030043
|
Q9BUF5,P04350,P21796,Q9NT62,P68371,P08670,Q9H9H4,Q9BVA1,O94826,O75143,Q99816,Q9Y3E7,O43633,Q8WUX9,Q8N4H5,Q13885,Q9NS69,P61088
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
657,218,3,661,322,567,764,269,136,635,726,348,396,281,404,439,60,745
|
2062,396,1173,635,136,2001,2216,218,1180,1133,567,2217,1402,1628,3,1140,1585,1053,2552,966,745,2121,2799,322,1410,746,2125,439,1524,1472,1360,930,404,281,2484,3220,2144,1937,726,657,269,764,60,661,1125,1440,348,2583,1081
|
-0.25285839803484295,0.8553872817591445,0.176073624778936,0.5597916419271479,1.7346152657608775,-0.22540238496379614,-0.33577561888619256,1.2818779400411169,0.176073624778936,0.20218202998275958,0.6345939747312106,-0.33577561888619256,0.07084569120510033,-0.035686956378783614,6.325246102229058,0.20218202998275958,-0.008928939691278415,0.25416528674662836,-0.5325682992306233,0.3058415118163126,0.45907851980090025,-0.28040536208862893,-0.7051470219004672,0.9997056275167767,0.07084569120510033,0.45907851980090025,-0.28040536208862893,0.806778655356379,0.017745346447724377,0.0443366457785035,0.0972732050141189,0.3315660934388125,0.8553872817591445,1.0946979225093583,-0.4758552031128107,-1.1232104786129942,-0.28040536208862893,-0.17075981630557494,0.4843631223961893,0.5597916419271479,1.1418385424299435,0.45907851980090025,2.624243454701938,0.5597916419271479,0.22821236301417117,0.07084569120510033,0.9518470676402865,-0.5325682992306233,0.25416528674662836
| 3,424
|
Regulation of exocytosis
| 9
| 39
| 2.169405
| 0.030052
|
Q9NQ11,P04083,P09601,Q06787,Q92783,Q9Y3E7,O43633,O00560,P30511
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,40,138,140,111,348,396,251,30
|
2826,251,951,396,1617,3062,1042,40,138,1183,2268,2299,832,2012,30,399,2172,571,2464,2117,2763,999,2765,1462,1810,140,3038,1311,1529,650,1219,111,726,65,2932,685,2207,1166,348
|
-0.7342769881754115,1.1887466003329457,0.3058415118163126,0.8553872817591445,-0.035686956378783614,-0.9412694483017089,0.25416528674662836,3.2172107186041283,1.7124644253307189,0.176073624778936,-0.36360068398579487,-0.3915202453943403,0.38279132997221815,-0.22540238496379614,3.558497153180639,0.8553872817591445,-0.3080441426423994,0.6345939747312106,-0.4758552031128107,-0.28040536208862893,-0.6761236824753828,0.28004145481948706,-0.6761236824753828,0.0443366457785035,-0.11647099443820123,1.7124644253307189,-0.9113604219611866,0.12361989908791096,0.017745346447724377,0.5597916419271479,0.176073624778936,2.039729696998139,0.4843631223961893,2.5835449672827635,-0.7928613254372211,0.534719116783902,-0.3080441426423994,0.20218202998275958,0.9518470676402865
| 3,424
|
Protease
| 24
| 87
| 2.154789
| 0.031178
|
Q99436,P52888,Q9HB40,P10619,P42785,P55210,Q2T9J0,Q9UPU5,Q5JRX3,Q9UIQ6,O14773,P55786,Q96FZ2,P28072,O75844,Q96K76,P28074,O43847,P42892,P67812,Q9H3G5,Q9NP73,Q9BYT8,Q9H8M7
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
128,10,11,139,14,272,274,282,279,29,162,163,301,43,64,69,77,212,92,220,98,232,379,249
|
1325,949,162,1327,212,3185,64,546,2263,713,505,139,737,1185,1847,43,77,3357,1797,2357,3385,836,14,92,1513,1802,3240,10,2362,1000,1052,272,163,2465,220,1753,1755,1002,454,747,2031,1708,474,274,1529,279,1151,1762,1111,850,1268,1651,3080,815,377,1114,1157,1068,301,69,723,625,2983,128,2144,2816,1022,379,2249,98,1604,2487,249,11,232,822,1989,2441,1946,767,29,768,282,1167,2583,2584,1612
|
0.0972732050141189,0.3058415118163126,1.5108548870512621,0.0972732050141189,1.3050204064717228,-1.0925841770213,2.5835449672827635,0.6593914757616174,-0.36360068398579487,0.4843631223961893,0.7087847380791157,1.7124644253307189,0.45907851980090025,0.176073624778936,-0.14357159543690104,3.1786497804219667,2.3776962925175247,-1.565741227335299,-0.11647099443820123,-0.41953522517290537,-1.7975625050538029,0.38279132997221815,4.388008865230443,2.210083029251862,0.017745346447724377,-0.11647099443820123,-1.1848376868304877,4.663727626155535,-0.41953522517290537,0.28004145481948706,0.25416528674662836,1.11829750855662,1.5108548870512621,-0.4758552031128107,1.2818779400411169,-0.08945721189541478,-0.08945721189541478,0.28004145481948706,0.7823779947173779,0.45907851980090025,-0.22540238496379614,-0.06252945841594201,0.7579124526698604,1.11829750855662,0.017745346447724377,1.0946979225093583,0.20218202998275958,-0.08945721189541478,0.22821236301417117,0.38279132997221815,0.1498864751122822,-0.035686956378783614,-0.9412694483017089,0.4082932133836793,0.9037421707307038,0.22821236301417117,0.20218202998275958,0.25416528674662836,1.0473214180574488,2.5016819168115965,0.4843631223961893,0.5847945955838018,-0.8518859430798013,1.8665043911430075,-0.28040536208862893,-0.7051470219004672,0.28004145481948706,0.9037421707307038,-0.33577561888619256,2.1889413177819854,-0.008928939691278415,-0.4758552031128107,1.212114435826368,4.663727626155535,1.2586797137259673,0.4082932133836793,-0.1980364707364708,-0.4476465603203489,-0.17075981630557494,0.45907851980090025,3.614405798250022,0.45907851980090025,1.0946979225093583,0.20218202998275958,-0.5325682992306233,-0.5325682992306233,-0.008928939691278415
| 3,424
|
Metalloprotease
| 15
| 26
| 2.151862
| 0.031408
|
O75844,P55786,P09960,Q9NQH7,O43847,Q9NZ08,P52888,O75976,Q9BYT8,Q96KP4,Q92905,P42892,P12955,Q5JRX3,Q9UIQ6
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
64,163,505,822,212,767,10,546,379,723,377,92,737,279,29
|
949,212,3185,64,546,505,737,1185,92,10,163,279,1111,850,377,723,2983,1022,379,1604,822,1989,1946,767,29,2584
|
0.3058415118163126,1.3050204064717228,-1.0925841770213,2.5835449672827635,0.6593914757616174,0.7087847380791157,0.45907851980090025,0.176073624778936,2.210083029251862,4.663727626155535,1.5108548870512621,1.0946979225093583,0.22821236301417117,0.38279132997221815,0.9037421707307038,0.4843631223961893,-0.8518859430798013,0.28004145481948706,0.9037421707307038,-0.008928939691278415,0.4082932133836793,-0.1980364707364708,-0.17075981630557494,0.45907851980090025,3.614405798250022,-0.5325682992306233
| 3,424
|
Positive regulation of actin filament polymerization
| 6
| 12
| 2.134081
| 0.032836
|
O95429,P62993,Q9UQB8,Q6ZU35,P35080,P07737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,353,17,24,399,435
|
2401,96,435,399,1140,536,353,1006,24,17,1665,1128
|
-0.4476465603203489,2.1889413177819854,0.806778655356379,0.8553872817591445,0.20218202998275958,0.6841215566363612,0.927825637672481,0.28004145481948706,3.8171415688003916,4.194804424150486,-0.035686956378783614,0.22821236301417117
| 3,424
|
Protein targeting to mitochondrion
| 14
| 56
| 2.127369
| 0.033389
|
O95429,P55786,Q9Y3D6,O94826,O60830,Q99595,O95831,Q9Y5J7,Q8N4H5,Q9Y584,Q5JRX3,O14925,Q9NS69,O14737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,163,430,136,12,16,331,208,404,250,279,305,60,94
|
1670,774,94,305,1327,1291,12,635,3185,136,2001,1734,96,1568,331,2216,1180,3239,1628,1962,2070,510,1635,2873,163,1199,1465,746,1472,1863,1865,2916,279,1215,404,1929,2429,1367,3391,16,1022,1158,2249,2665,60,1389,1164,3106,2860,430,1835,250,431,208,1037,2292
|
-0.06252945841594201,0.4337220787410696,2.1889413177819854,1.0235436493047718,0.0972732050141189,0.12361989908791096,4.629595354354387,0.5597916419271479,-1.0925841770213,1.7346152657608775,-0.22540238496379614,-0.08945721189541478,2.1889413177819854,-0.008928939691278415,0.9758069147141267,-0.33577561888619256,0.176073624778936,-1.1848376868304877,-0.035686956378783614,-0.1980364707364708,-0.25285839803484295,0.7087847380791157,-0.035686956378783614,-0.763514707401799,1.5108548870512621,0.176073624778936,0.0443366457785035,0.45907851980090025,0.0443366457785035,-0.14357159543690104,-0.14357159543690104,-0.7928613254372211,1.0946979225093583,0.176073624778936,0.8553872817591445,-0.17075981630557494,-0.4476465603203489,0.0972732050141189,-1.899302791396063,4.2830041272536015,0.28004145481948706,0.20218202998275958,-0.33577561888619256,-0.5896824508203791,2.624243454701938,0.0972732050141189,0.20218202998275958,-0.9712946918324333,-0.7342769881754115,0.8311149234361495,-0.11647099443820123,1.212114435826368,0.8311149234361495,1.3511395792365377,0.28004145481948706,-0.36360068398579487
| 3,424
|
Negative regulation of defense response
| 11
| 37
| 2.119779
| 0.034025
|
Q9H000,Q96J02,Q9Y3Z3,Q16539,P78540,P28070,P00813,O43657,P19474,P04062,P30511
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
427,66,498,455,489,45,146,238,121,368,30
|
238,1086,146,3024,368,1400,2407,2167,121,1453,45,30,1910,2546,674,3034,489,2802,1003,2078,1101,846,455,1010,2378,1713,2567,1767,66,524,855,427,3362,730,498,1167,2494
|
1.2354253422253956,0.22821236301417117,1.6680148523611502,-0.9113604219611866,0.9037421707307038,0.07084569120510033,-0.4476465603203489,-0.3080441426423994,1.9100875739304093,0.0443366457785035,3.081664317034927,3.558497153180639,-0.17075981630557494,-0.5325682992306233,0.534719116783902,-0.9113604219611866,0.7333815342116367,-0.7051470219004672,0.28004145481948706,-0.25285839803484295,0.22821236301417117,0.38279132997221815,0.7823779947173779,0.28004145481948706,-0.41953522517290537,-0.06252945841594201,-0.5325682992306233,-0.08945721189541478,2.5631377808237996,0.7087847380791157,0.38279132997221815,0.8311149234361495,-1.5983998609621628,0.4843631223961893,0.7333815342116367,0.20218202998275958,-0.4758552031128107
| 3,424
|
Deoxyribose phosphate metabolic process
| 8
| 14
| 2.107688
| 0.035058
|
Q9H773,Q9Y3Z3,P00491,P34896,P31350,P04818,P00813,Q96G03
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,498,566,384,417,449,146,705
|
566,146,449,2011,1508,417,1137,696,384,2073,1259,705,0,498
|
0.6345939747312106,1.6680148523611502,0.7823779947173779,-0.22540238496379614,0.017745346447724377,0.8311149234361495,0.20218202998275958,0.5095764645830615,0.8795962071847374,-0.25285839803484295,0.1498864751122822,0.5095764645830615,8.407992880482578,0.7333815342116367
| 3,424
|
Protein transporter activity
| 7
| 16
| 2.091262
| 0.036505
|
O94826,O60830,Q9UGP8,Q99595,Q9Y584,O14925,Q9NS69
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
136,12,412,16,250,305,60
|
305,12,136,2216,1804,2766,2842,1472,2887,16,983,60,412,250,431,1037
|
1.0235436493047718,4.629595354354387,1.7346152657608775,-0.33577561888619256,-0.11647099443820123,-0.6761236824753828,-0.7342769881754115,0.0443366457785035,-0.763514707401799,4.2830041272536015,0.3058415118163126,2.624243454701938,0.8553872817591445,1.212114435826368,0.8311149234361495,0.28004145481948706
| 3,424
|
Autophagosome membrane
| 7
| 19
| 2.055575
| 0.039824
|
Q9NQ11,O95721,O15321,Q96GC9,P56962,Q9Y3E7,Q8WUX9
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
65,252,75,47,147,348,281
|
75,396,1957,252,2866,2268,1402,2464,147,966,281,47,1119,65,1437,1125,2860,348,1562
|
2.3776962925175247,0.8553872817591445,-0.1980364707364708,1.1887466003329457,-0.763514707401799,-0.36360068398579487,0.07084569120510033,-0.4758552031128107,1.6680148523611502,0.3058415118163126,1.0946979225093583,3.0621659370708794,0.22821236301417117,2.5835449672827635,0.07084569120510033,0.22821236301417117,-0.7342769881754115,0.9518470676402865,0.017745346447724377
| 3,424
|
Protein localization to vacuole
| 6
| 23
| 2.054758
| 0.039902
|
Q9NQ11,P20645,Q92783,Q9Y2T2,Q14108,Q9BRG1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,97,111,207,19,222
|
1996,1083,503,2217,1402,97,1301,2464,840,19,1871,111,2814,527,1937,222,764,65,660,234,1166,207,2860
|
-0.22540238496379614,0.22821236301417117,0.7087847380791157,-0.33577561888619256,0.07084569120510033,2.1889413177819854,0.12361989908791096,-0.4758552031128107,0.38279132997221815,4.016451430021635,-0.14357159543690104,2.039729696998139,-0.7051470219004672,0.7087847380791157,-0.17075981630557494,1.2818779400411169,0.45907851980090025,2.5835449672827635,0.5597916419271479,1.2586797137259673,0.20218202998275958,1.3511395792365377,-0.7342769881754115
| 3,424
|
Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
| 8
| 37
| 2.053611
| 0.040013
|
Q96FV9,P04083,Q96FZ2,P00813,Q9NUQ9,Q9UQ84,Q16512,P30511
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
268,40,301,146,149,85,155,30
|
2863,1956,295,992,146,3024,911,40,1400,714,3239,30,2761,876,673,1140,916,878,1000,840,1003,2078,2230,2419,155,1530,3191,3006,1534,2776,268,301,2323,791,2781,149,85
|
-0.763514707401799,-0.1980364707364708,1.0473214180574488,0.28004145481948706,1.6680148523611502,-0.9113604219611866,0.3315660934388125,3.2172107186041283,0.07084569120510033,0.4843631223961893,-1.1848376868304877,3.558497153180639,-0.6761236824753828,0.3572158266764965,0.534719116783902,0.20218202998275958,0.3315660934388125,0.3572158266764965,0.28004145481948706,0.38279132997221815,0.28004145481948706,-0.25285839803484295,-0.33577561888619256,-0.4476465603203489,1.5560133657211266,0.017745346447724377,-1.0925841770213,-0.8815663376382865,0.017745346447724377,-0.6761236824753828,1.1418385424299435,1.0473214180574488,-0.3915202453943403,0.4337220787410696,-0.6761236824753828,1.6680148523611502,2.2942243165759035
| 3,424
|
SLC superfamily of solute carriers
| 10
| 52
| 2.027208
| 0.042641
|
Q5T1Q4,Q9Y619,Q6NT16,Q9BSK2,P41440,Q70HW3,Q8IXU6,O43772,O00400,Q96H78
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
36,166,201,141,110,243,50,25,123,57
|
123,2449,25,2830,1999,1733,2265,2994,1905,1846,2108,253,110,2224,2682,2276,2684,2367,1646,1418,36,2850,201,1763,3369,2476,786,243,50,1928,2520,598,2240,57,1481,1482,725,727,141,1376,1380,446,3200,2489,3314,2780,1993,862,1784,166,2059,1242
|
1.8883193828815668,-0.4758552031128107,3.7988551199513982,-0.7342769881754115,-0.22540238496379614,-0.08945721189541478,-0.36360068398579487,-0.8815663376382865,-0.17075981630557494,-0.14357159543690104,-0.28040536208862893,1.1887466003329457,2.039729696998139,-0.33577561888619256,-0.6183924757333895,-0.36360068398579487,-0.6183924757333895,-0.41953522517290537,-0.035686956378783614,0.07084569120510033,3.408070428891878,-0.7342769881754115,1.374117034728647,-0.08945721189541478,-1.631208032298414,-0.4758552031128107,0.4337220787410696,1.2354253422253956,2.9444523367001354,-0.17075981630557494,-0.5041621214531338,0.6097285261007889,-0.33577561888619256,2.7654929017330954,0.0443366457785035,0.0443366457785035,0.4843631223961893,0.4843631223961893,1.7124644253307189,0.0972732050141189,0.0972732050141189,0.806778655356379,-1.0925841770213,-0.4758552031128107,-1.3411607415134839,-0.6761236824753828,-0.1980364707364708,0.38279132997221815,-0.08945721189541478,1.5108548870512621,-0.22540238496379614,0.176073624778936
| 3,424
|
Postural tremor
| 8
| 23
| 2.023863
| 0.042984
|
P04350,Q9NQ11,O14773,Q9NR77,O75306,Q06787,Q14108,P03886
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
218,65,162,262,258,140,19,87
|
162,1730,258,991,2001,2716,3383,87,1680,218,2793,287,2019,140,19,2192,2144,2659,461,1026,65,262,2442
|
1.5108548870512621,-0.08945721189541478,1.165321436994088,0.28004145481948706,-0.22540238496379614,-0.6472058630830041,-1.7639761848109017,2.2732523402364393,-0.06252945841594201,1.2818779400411169,-0.7051470219004672,1.0710393665641098,-0.22540238496379614,1.7124644253307189,4.016451430021635,-0.3080441426423994,-0.28040536208862893,-0.5896824508203791,0.7823779947173779,0.28004145481948706,2.5835449672827635,1.165321436994088,-0.4476465603203489
| 3,424
|
Membrane lipid metabolic process
| 13
| 44
| 2.023475
| 0.043024
|
P30153,P27544,Q06136,O15270,Q96G23,P07602,O95470,Q9NZD2,Q8NBX0,P50897,Q13510,P06280,Q8NCC3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
320,103,108,204,206,115,239,347,216,26,91,153,345
|
829,204,634,1327,1841,239,368,691,153,548,115,2792,639,777,2010,103,320,26,1003,108,746,91,2916,2316,2375,216,345,815,2656,206,2048,3333,1318,3264,2932,1552,2097,3128,347,1993,2252,3183,769,867
|
0.38279132997221815,1.3511395792365377,0.5597916419271479,0.0972732050141189,-0.14357159543690104,1.2354253422253956,0.9037421707307038,0.5095764645830615,1.5560133657211266,0.6593914757616174,1.975114183919561,-0.7051470219004672,0.5597916419271479,0.4337220787410696,-0.22540238496379614,2.1039414474895977,0.9997056275167767,3.743824687447206,0.28004145481948706,2.061178120380909,0.45907851980090025,2.231181939560065,-0.7928613254372211,-0.3915202453943403,-0.41953522517290537,1.3050204064717228,0.9518470676402865,0.4082932133836793,-0.5896824508203791,1.3511395792365377,-0.22540238496379614,-1.4365640802810167,0.12361989908791096,-1.215841528185196,-0.7928613254372211,0.017745346447724377,-0.25285839803484295,-1.001437451234241,0.9518470676402865,-0.1980364707364708,-0.33577561888619256,-1.0620808335875023,0.45907851980090025,0.38279132997221815
| 3,424
|
Response to elevated platelet cytosolic ca2
| 11
| 36
| 2.021281
| 0.043251
|
Q8NBM8,Q9NTK5,Q9UEU0,Q08380,O15439,P07602,Q9NUQ9,Q8NBX0,O43852,P07737,Q92520
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
134,202,630,242,484,115,149,216,340,435,358
|
2826,484,1084,340,2497,609,2105,1179,115,435,1184,1402,1451,1335,2833,1452,1511,1855,1918,242,3038,974,2041,134,216,358,1821,2390,202,149,1993,630,3223,1285,2058,1562
|
-0.7342769881754115,0.7333815342116367,0.22821236301417117,0.9518470676402865,-0.5041621214531338,0.5847945955838018,-0.28040536208862893,0.176073624778936,1.975114183919561,0.806778655356379,0.176073624778936,0.07084569120510033,0.0443366457785035,0.0972732050141189,-0.7342769881754115,0.0443366457785035,0.017745346447724377,-0.14357159543690104,-0.17075981630557494,1.2354253422253956,-0.9113604219611866,0.3058415118163126,-0.22540238496379614,1.7567172231726083,1.3050204064717228,0.927825637672481,-0.11647099443820123,-0.41953522517290537,1.374117034728647,1.6680148523611502,-0.1980364707364708,0.5847945955838018,-1.1232104786129942,0.1498864751122822,-0.22540238496379614,0.017745346447724377
| 3,424
|
Postaxial polydactyly
| 9
| 27
| 2.017939
| 0.043598
|
Q96J42,P30153,O43924,Q9Y366,Q15125,Q2M1P5,O75845,Q8NCM8,O75665
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
99,320,7,381,209,183,89,157,95
|
3413,7,95,89,1451,2009,2833,320,1258,698,1465,386,209,183,808,157,1114,2385,99,3051,759,2393,1663,2397,1284,665,381
|
-2.6951538272125575,5.246628713778516,2.1889413177819854,2.231181939560065,0.0443366457785035,-0.22540238496379614,-0.7342769881754115,0.9997056275167767,0.1498864751122822,0.5095764645830615,0.0443366457785035,0.8795962071847374,1.3281074939758217,1.442725285577121,0.4082932133836793,1.5560133657211266,0.22821236301417117,-0.41953522517290537,2.167756556317077,-0.9113604219611866,0.45907851980090025,-0.41953522517290537,-0.035686956378783614,-0.41953522517290537,0.1498864751122822,0.5597916419271479,0.9037421707307038
| 3,424
|
Sterol metabolic process
| 12
| 42
| 2.010338
| 0.044395
|
Q9UKR5,Q16850,Q9BQE5,Q8WTV0,Q14739,O15118,Q15392,Q15125,Q15800,P35610,O75845,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
197,131,67,37,386,106,44,209,84,240,89,368
|
106,1041,89,2345,2539,3209,368,1179,1683,610,1960,3254,3166,240,3031,3409,3032,436,1303,1193,1053,2120,2227,2950,2802,746,1644,1594,386,209,1355,44,2514,84,131,37,67,1552,1663,1723,3223,197
|
2.061178120380909,0.25416528674662836,2.231181939560065,-0.41953522517290537,-0.5325682992306233,-1.1232104786129942,0.9037421707307038,0.176073624778936,-0.06252945841594201,0.5847945955838018,-0.1980364707364708,-1.215841528185196,-1.0620808335875023,1.2354253422253956,-0.9113604219611866,-2.5063238140704884,-0.9113604219611866,0.806778655356379,0.12361989908791096,0.176073624778936,0.25416528674662836,-0.28040536208862893,-0.33577561888619256,-0.8223180083817365,-0.7051470219004672,0.45907851980090025,-0.035686956378783614,-0.008928939691278415,0.8795962071847374,1.3281074939758217,0.0972732050141189,3.1011287111609,-0.5041621214531338,2.2942243165759035,1.82273284893905,3.408070428891878,2.522206469103894,0.017745346447724377,-0.035686956378783614,-0.06252945841594201,-1.1232104786129942,1.3970402287838317
| 3,424
|
Ciliopathy
| 6
| 15
| 2.009524
| 0.044482
|
Q9UBB4,Q96J42,O43924,Q2M1P5,Q8NCM8,O75665
|
Drugs and Diseases
|
Protein Atlas Disease involvement
|
protein_atlas_disease_involvement
|
257,99,7,183,157,95
|
7,95,1800,2837,838,183,622,157,2385,99,759,2393,257,1284,381
|
5.246628713778516,2.1889413177819854,-0.11647099443820123,-0.7342769881754115,0.38279132997221815,1.442725285577121,0.5847945955838018,1.5560133657211266,-0.41953522517290537,2.167756556317077,0.45907851980090025,-0.41953522517290537,1.1887466003329457,0.1498864751122822,0.9037421707307038
| 3,424
|
Peptide binding
| 22
| 72
| 2.003576
| 0.045116
|
O94826,P52294,Q8TEX9,P09496,Q9UIQ6,P30511,P24390,O14773,P55786,Q8WTV0,Q92973,Q15392,O00505,Q03519,O43813,O00410,P42892,P61758,Q9Y3C6,Q9NQX7,Q9BYT8,Q9Y584
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
136,9,405,271,29,30,33,162,163,37,300,44,175,182,316,330,92,342,365,380,379,250
|
948,330,175,162,1898,1131,2103,316,136,3024,1400,1133,271,692,485,1185,1506,2718,33,2681,3292,30,3165,2356,1510,400,92,3188,1340,2974,2463,2361,9,2362,163,537,1974,2766,342,1975,844,182,925,2228,1642,2877,2724,806,3358,1472,44,1111,405,37,300,2852,2434,526,3333,2437,379,2486,901,902,380,767,1782,1607,29,2335,365,250
|
0.3058415118163126,0.9758069147141267,1.465487864832413,1.5108548870512621,-0.17075981630557494,0.20218202998275958,-0.28040536208862893,0.9997056275167767,1.7346152657608775,-0.9113604219611866,0.07084569120510033,0.20218202998275958,1.11829750855662,0.5095764645830615,0.7333815342116367,0.176073624778936,0.017745346447724377,-0.6472058630830041,3.4458619829507984,-0.6183924757333895,-1.3096322187119562,3.558497153180639,-1.0620808335875023,-0.41953522517290537,0.017745346447724377,0.8553872817591445,2.210083029251862,-1.0925841770213,0.0972732050141189,-0.8518859430798013,-0.4758552031128107,-0.41953522517290537,5.066275194941922,-0.41953522517290537,1.5108548870512621,0.6841215566363612,-0.1980364707364708,-0.6761236824753828,0.9518470676402865,-0.1980364707364708,0.38279132997221815,1.442725285577121,0.3315660934388125,-0.33577561888619256,-0.035686956378783614,-0.763514707401799,-0.6472058630830041,0.4082932133836793,-1.565741227335299,0.0443366457785035,3.1011287111609,0.22821236301417117,0.8553872817591445,3.408070428891878,1.0473214180574488,-0.7342769881754115,-0.4476465603203489,0.7087847380791157,-1.4365640802810167,-0.4476465603203489,0.9037421707307038,-0.4758552031128107,0.3572158266764965,0.3572158266764965,0.9037421707307038,0.45907851980090025,-0.08945721189541478,-0.008928939691278415,3.614405798250022,-0.3915202453943403,0.927825637672481,1.212114435826368
| 3,424
|
Translocation of slc2a4 glut4 to the plasma membrane
| 22
| 40
| 2.00331
| 0.045144
|
Q9BUF5,Q9BZE9,Q9BVA1,Q96KP1,O60343,Q9UIQ6,Q9UPT5,Q04917,O00471,Q8IYI6,P63104,Q13885,Q96A65,P31751,Q9NV70,P31749,P68371,P61981,P31946,P04350,P62258,Q9Y496
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
657,135,269,935,532,29,1079,1057,794,171,922,439,704,308,329,695,322,968,961,218,841,770
|
2445,2061,2826,794,532,1840,218,1183,1572,1454,695,308,961,1338,2763,1585,1053,2765,1462,1696,968,841,2025,922,322,1057,3038,439,171,1983,704,935,657,269,135,329,29,1079,1726,770
|
-0.4758552031128107,-0.25285839803484295,-0.7342769881754115,0.4082932133836793,0.6841215566363612,-0.14357159543690104,1.2818779400411169,0.176073624778936,-0.008928939691278415,0.0443366457785035,0.5095764645830615,1.0235436493047718,0.3058415118163126,0.0972732050141189,-0.6761236824753828,-0.008928939691278415,0.25416528674662836,-0.6761236824753828,0.0443366457785035,-0.06252945841594201,0.3058415118163126,0.38279132997221815,-0.22540238496379614,0.3315660934388125,0.9997056275167767,0.25416528674662836,-0.9113604219611866,0.806778655356379,1.4881976158068801,-0.1980364707364708,0.5095764645830615,0.3315660934388125,0.5597916419271479,1.1418385424299435,1.7567172231726083,0.9997056275167767,3.614405798250022,0.25416528674662836,-0.06252945841594201,0.45907851980090025
| 3,424
|
Ub specific processing proteases
| 17
| 76
| 1.997263
| 0.045797
|
Q99436,P60900,P21796,Q96K76,P49721,O94826,Q92530,P28072,Q14997,P45880,P25788,O75832,P28070,Q9Y6K9,P28074,Q9UPU5,P20618
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,3,69,8,136,172,43,355,13,416,415,45,315,77,282,55
|
499,1896,949,1837,689,1328,3402,415,136,2263,3210,1185,1627,55,3,1453,1048,416,1849,1337,45,43,77,1910,2071,3385,1582,13,1513,877,918,8,1305,1052,1638,160,645,1347,1348,1518,616,3295,2419,454,2178,1146,2600,2031,355,1470,1472,927,2032,1651,2321,172,1767,1114,1157,1068,69,625,128,1370,2149,3054,1122,563,1556,768,282,2492,1724,3108,1167,315
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,0.0972732050141189,-2.2858818540375703,0.8311149234361495,1.7346152657608775,-0.36360068398579487,-1.1232104786129942,0.176073624778936,-0.035686956378783614,2.7855222848906425,6.325246102229058,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.17075981630557494,-0.25285839803484295,-1.7975625050538029,-0.008928939691278415,4.561049497959283,0.017745346447724377,0.3572158266764965,0.3315660934388125,5.197689907839026,0.12361989908791096,0.25416528674662836,-0.035686956378783614,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.5847945955838018,-1.3096322187119562,-0.4476465603203489,0.7823779947173779,-0.3080441426423994,0.20218202998275958,-0.5610747366914889,-0.22540238496379614,0.927825637672481,0.0443366457785035,0.0443366457785035,0.3315660934388125,-0.22540238496379614,-0.035686956378783614,-0.3915202453943403,1.4881976158068801,-0.08945721189541478,0.22821236301417117,0.20218202998275958,0.25416528674662836,2.5016819168115965,0.5847945955838018,1.8665043911430075,0.0972732050141189,-0.28040536208862893,-0.9113604219611866,0.22821236301417117,0.6593914757616174,0.017745346447724377,0.45907851980090025,1.0946979225093583,-0.4758552031128107,-0.06252945841594201,-0.9712946918324333,0.20218202998275958,1.0235436493047718
| 3,424
|
Abnormal enchondral ossification
| 9
| 31
| 1.995154
| 0.046026
|
Q9Y619,Q14739,O00116,O96028,Q15125,P10644,Q2M1P5,P40855,Q8NCM8
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
166,386,225,295,209,53,183,400,157
|
225,2498,1998,1733,1044,295,53,2833,2357,1579,400,1972,1974,2280,386,1147,209,2514,183,517,157,2696,2385,2287,2524,2441,1663,2160,1284,2057,166
|
1.2586797137259673,-0.5041621214531338,-0.22540238496379614,-0.08945721189541478,0.25416528674662836,1.0473214180574488,2.825471169603632,-0.7342769881754115,-0.41953522517290537,-0.008928939691278415,0.8553872817591445,-0.1980364707364708,-0.1980364707364708,-0.36360068398579487,0.8795962071847374,0.20218202998275958,1.3281074939758217,-0.5041621214531338,1.442725285577121,0.7087847380791157,1.5560133657211266,-0.6183924757333895,-0.41953522517290537,-0.36360068398579487,-0.5041621214531338,-0.4476465603203489,-0.035686956378783614,-0.28040536208862893,0.1498864751122822,-0.22540238496379614,1.5108548870512621
| 3,424
|
Synthesis of dna
| 18
| 84
| 1.978462
| 0.047877
|
Q99436,P60900,Q9NR33,Q9Y619,P49721,Q92530,Q14997,P28072,P28340,P28074,P28070,P41440,P25205,Q13042,P25788,O75832,P20618,P15927
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
128,160,233,166,8,172,355,43,383,77,45,110,176,273,416,415,55,369
|
499,1896,949,1837,689,2899,2452,415,1134,798,369,1627,2412,55,1092,176,1453,1048,416,1849,1252,1337,45,43,77,383,2170,1457,1577,1049,1509,2869,2355,2462,2071,2273,1300,1743,110,1582,877,778,1190,1852,918,8,1460,1305,1638,2553,160,645,1347,1348,1518,842,616,677,273,2178,1146,1206,971,355,1470,1815,172,443,128,1370,789,1884,1940,233,1434,2672,1236,1492,1555,563,1556,825,1895,166
|
0.7087847380791157,-0.17075981630557494,0.3058415118163126,-0.14357159543690104,0.5095764645830615,-0.7928613254372211,-0.4758552031128107,0.8311149234361495,0.20218202998275958,0.4082932133836793,0.9037421707307038,-0.035686956378783614,-0.4476465603203489,2.7855222848906425,0.22821236301417117,1.465487864832413,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.1498864751122822,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,0.8795962071847374,-0.3080441426423994,0.0443366457785035,-0.008928939691278415,0.25416528674662836,0.017745346447724377,-0.763514707401799,-0.41953522517290537,-0.4758552031128107,-0.25285839803484295,-0.36360068398579487,0.12361989908791096,-0.08945721189541478,2.039729696998139,-0.008928939691278415,0.3572158266764965,0.4337220787410696,0.176073624778936,-0.14357159543690104,0.3315660934388125,5.197689907839026,0.0443366457785035,0.12361989908791096,-0.035686956378783614,-0.5325682992306233,1.5334600233386158,0.5597916419271479,0.0972732050141189,0.0972732050141189,0.017745346447724377,0.38279132997221815,0.5847945955838018,0.534719116783902,1.11829750855662,-0.3080441426423994,0.20218202998275958,0.176073624778936,0.3058415118163126,0.927825637672481,0.0443366457785035,-0.11647099443820123,1.4881976158068801,0.806778655356379,1.8665043911430075,0.0972732050141189,0.4337220787410696,-0.14357159543690104,-0.17075981630557494,1.2586797137259673,0.07084569120510033,-0.5896824508203791,0.176073624778936,0.0443366457785035,0.017745346447724377,0.6593914757616174,0.017745346447724377,0.4082932133836793,-0.14357159543690104,1.5108548870512621
| 3,424
|
Anchoring of the basal body to the plasma membrane
| 14
| 36
| 1.974043
| 0.048377
|
P04350,P68371,O94927,P30153,P07437,O95684,P06493,O43805,P41208,Q15154,Q96CS2,Q9H6D7,O75935,O75665
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
218,322,192,320,318,504,589,107,177,372,276,217,434,95
|
107,95,434,192,504,218,589,318,1180,1451,2009,2461,320,177,2305,2551,2765,921,968,841,2121,322,2125,782,2281,1005,1524,1311,372,784,810,650,276,3222,217,3377
|
2.061178120380909,2.1889413177819854,0.806778655356379,1.3970402287838317,0.7087847380791157,1.2818779400411169,0.6097285261007889,0.9997056275167767,0.176073624778936,0.0443366457785035,-0.22540238496379614,-0.4758552031128107,0.9997056275167767,1.465487864832413,-0.3915202453943403,-0.5325682992306233,-0.6761236824753828,0.3315660934388125,0.3058415118163126,0.38279132997221815,-0.28040536208862893,0.9997056275167767,-0.28040536208862893,0.4337220787410696,-0.36360068398579487,0.28004145481948706,0.017745346447724377,0.12361989908791096,0.9037421707307038,0.4337220787410696,0.4082932133836793,0.5597916419271479,1.11829750855662,-1.1232104786129942,1.3050204064717228,-1.697280917985091
| 3,424
|
Alzheimers disease and mirna effects
| 27
| 89
| 1.97205
| 0.048604
|
Q9BUF5,Q99436,P21796,Q9NQC3,P49721,Q9BVA1,P45880,P55210,O95197,P60900,P28072,P28070,P25788,Q96GC9,P20618,P31751,Q13885,Q07866,P68371,P49841,P07437,P28074,Q9H0B6,P04350,P48729,O15111,Q9P2E5
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
657,128,3,660,8,269,13,272,398,160,43,45,416,47,55,308,439,574,322,571,318,77,602,218,228,483,394
|
1896,3413,949,1954,1837,483,689,635,398,218,2630,1179,2265,1401,713,318,1846,2108,1185,2299,1847,1627,1795,1628,55,3,1453,1048,416,1849,1093,1337,45,43,77,2271,3292,695,308,1188,2272,2071,1140,836,1582,13,877,228,837,918,8,571,1305,1638,272,160,1347,1348,1518,2799,322,1810,1756,574,925,2228,1642,2419,2178,1523,439,1470,2032,2042,1820,47,2142,128,1370,1937,3180,657,269,602,660,1234,394,1556,1724
|
-0.17075981630557494,-2.6951538272125575,0.3058415118163126,-0.1980364707364708,-0.14357159543690104,0.7333815342116367,0.5095764645830615,0.5597916419271479,0.8553872817591445,1.2818779400411169,-0.5896824508203791,0.176073624778936,-0.36360068398579487,0.07084569120510033,0.4843631223961893,0.9997056275167767,-0.14357159543690104,-0.28040536208862893,0.176073624778936,-0.3915202453943403,-0.14357159543690104,-0.035686956378783614,-0.11647099443820123,-0.035686956378783614,2.7855222848906425,6.325246102229058,0.0443366457785035,0.25416528674662836,0.8311149234361495,-0.14357159543690104,0.22821236301417117,0.0972732050141189,3.081664317034927,3.1786497804219667,2.3776962925175247,-0.36360068398579487,-1.3096322187119562,0.5095764645830615,1.0235436493047718,0.176073624778936,-0.36360068398579487,-0.25285839803484295,0.20218202998275958,0.38279132997221815,-0.008928939691278415,4.561049497959283,0.3572158266764965,1.2586797137259673,0.38279132997221815,0.3315660934388125,5.197689907839026,0.6345939747312106,0.12361989908791096,-0.035686956378783614,1.11829750855662,1.5334600233386158,0.0972732050141189,0.0972732050141189,0.017745346447724377,-0.7051470219004672,0.9997056275167767,-0.11647099443820123,-0.08945721189541478,0.6345939747312106,0.3315660934388125,-0.33577561888619256,-0.035686956378783614,-0.4476465603203489,-0.3080441426423994,0.017745346447724377,0.806778655356379,0.0443366457785035,-0.22540238496379614,-0.22540238496379614,-0.11647099443820123,3.0621659370708794,-0.28040536208862893,1.8665043911430075,0.0972732050141189,-0.17075981630557494,-1.0620808335875023,0.5597916419271479,1.1418385424299435,0.6097285261007889,0.5597916419271479,0.176073624778936,0.8795962071847374,0.017745346447724377,-0.06252945841594201
| 3,424
|
Cilium assembly
| 32
| 69
| 1.966097
| 0.049287
|
Q9BUF5,Q7Z460,O43924,Q9BVA1,O95684,Q15691,Q13561,Q96CS2,Q8NCM8,O00471,Q92973,Q8IYI6,P41208,Q96A65,Q13885,Q9NV70,O75935,P18085,P68371,O94927,A6NIH7,P07437,P30153,P06493,Q9H6D7,O75665,P04350,Q9BW83,O43805,Q9Y496,Q9Y366,Q15154
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
657,650,7,269,504,784,782,276,157,794,300,171,177,704,439,329,434,694,322,192,191,318,320,589,217,95,218,759,107,770,381,372
|
1324,191,794,107,7,1840,95,2865,434,192,504,218,589,318,1180,1451,2009,1689,694,2461,320,1800,177,2305,2173,1515,1967,1805,2551,2765,921,968,841,2121,322,1522,1465,2125,782,439,2281,1005,1524,1311,372,784,810,650,171,157,1983,1366,300,704,276,2385,2484,935,3222,657,269,759,217,2393,329,3377,1079,381,770
|
0.0972732050141189,1.3970402287838317,0.4082932133836793,2.061178120380909,5.246628713778516,-0.14357159543690104,2.1889413177819854,-0.763514707401799,0.806778655356379,1.3970402287838317,0.7087847380791157,1.2818779400411169,0.6097285261007889,0.9997056275167767,0.176073624778936,0.0443366457785035,-0.22540238496379614,-0.06252945841594201,0.5095764645830615,-0.4758552031128107,0.9997056275167767,-0.11647099443820123,1.465487864832413,-0.3915202453943403,-0.3080441426423994,0.017745346447724377,-0.1980364707364708,-0.11647099443820123,-0.5325682992306233,-0.6761236824753828,0.3315660934388125,0.3058415118163126,0.38279132997221815,-0.28040536208862893,0.9997056275167767,0.017745346447724377,0.0443366457785035,-0.28040536208862893,0.4337220787410696,0.806778655356379,-0.36360068398579487,0.28004145481948706,0.017745346447724377,0.12361989908791096,0.9037421707307038,0.4337220787410696,0.4082932133836793,0.5597916419271479,1.4881976158068801,1.5560133657211266,-0.1980364707364708,0.0972732050141189,1.0473214180574488,0.5095764645830615,1.11829750855662,-0.41953522517290537,-0.4758552031128107,0.3315660934388125,-1.1232104786129942,0.5597916419271479,1.1418385424299435,0.45907851980090025,1.3050204064717228,-0.41953522517290537,0.9997056275167767,-1.697280917985091,0.25416528674662836,0.9037421707307038,0.45907851980090025
| 3,424
|
Transporter activity
| 79
| 196
| 5.123057
| 0
|
P03915,O60830,Q99595,P21796,Q7KZN9,P45880,Q9NS69,Q9Y5P4,Q6P4A7,O43676,P24539,Q9Y584,Q96H78,Q9UDW1,Q13423,O75964,P30825,Q8NE01,Q8WTV0,Q9UJS0,Q9C0H2,P03886,P04062,P53985,Q6NUK1,O00400,O15118,Q9NQ11,Q8TB61,Q9UBX3,P00846,Q70HW3,O43772,Q96AA3,Q9H2D1,P17900,O75306,Q5T1Q4,Q8N4V1,P51790,Q9Y619,Q9Y277,Q99797,O15173,Q96ES6,Q8IXU6,Q03519,P20020,P30536,Q9HD20,Q9BZF1,Q9BSK2,Q6NT16,Q9BQT8,P35670,Q8NEW0,O43681,Q8N1S5,P08183,Q15043,Q9Y6M9,P49755,O43674,O14925,Q6NXT4,Q6PML9,P20674,Q14728,Q9UGP8,Q9Y6M7,O95202,O95167,Q9Y5J9,Q15388,P36383,O95168,P41440,Q93050,P12235
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
507,2,1,5,529,14,18,544,538,39,547,44,47,48,560,56,571,582,64,586,70,69,80,591,604,86,97,101,109,111,121,133,143,152,157,166,173,183,186,204,221,220,223,229,231,233,236,235,242,244,261,288,300,305,307,314,311,327,322,335,339,343,341,340,348,349,353,366,389,390,382,381,411,416,430,445,458,473,469
|
738,3408,2315,86,1622,931,1528,340,1746,97,229,2514,341,39,1748,311,143,813,2,1833,2186,173,1576,1897,1140,1496,56,1380,1244,381,445,1382,2054,382,2478,637,1457,914,121,69,507,80,916,1533,949,1178,1704,2946,322,2151,1211,2923,1753,1274,469,664,762,1101,724,166,2770,235,353,982,2104,5,2284,547,2851,871,3344,242,571,2326,666,307,430,839,1008,934,1841,458,14,1544,3204,743,343,3334,204,2385,764,1635,1674,591,1067,1249,1185,2067,600,2900,1218,780,1721,2203,1550,1640,236,798,560,3220,366,1393,335,416,1015,2535,799,183,3394,300,604,348,1814,538,1291,349,133,529,3256,233,327,186,1361,582,1509,314,109,64,1975,473,152,964,231,676,47,1022,1735,803,703,889,1,223,1230,2909,305,288,2965,1933,968,261,757,70,1299,157,2040,1201,1883,907,1406,244,101,2044,18,3406,834,736,1128,111,48,389,2178,1339,586,1056,2412,220,634,44,1170,411,1031,544,221,3333,390,339
|
0.4339317726253653,-2.4725910422416124,-0.43569894708233464,2.5425880302168293,-0.13496893733397167,0.24879026863223094,-0.09573868680970035,1.10136302234031,-0.19418721956236745,2.3984830795821077,1.4807753146449134,-0.5179207785497725,1.10136302234031,3.33632142390138,-0.19418721956236745,1.1685858128764244,1.9973622966526008,0.36038744680166185,5.203448495367863,-0.23391832955023042,-0.3746072665047304,1.7975170034836079,-0.11532915716857117,-0.25386051882213734,0.11658683691935393,-0.07619722251063903,3.0567507737172264,-0.017863872838918923,0.05924575850806966,0.999504346348033,0.8617217363584101,-0.017863872838918923,-0.31399754246940065,0.999504346348033,-0.4972821326535668,0.5610423537706956,-0.056704463496115395,0.2674983597767239,2.162978192726338,2.8655806296701516,0.7744260494954054,2.62795906725318,0.2674983597767239,-0.09573868680970035,0.23003816681518965,0.09751936170847361,-0.1743976571717926,-0.7487318629297377,1.1350418152893942,-0.3543509374216771,0.0784057608191252,-0.7274549681465066,-0.19418721956236745,0.04003907639528579,0.8269144177911181,0.5249283688242936,0.41560864305026346,0.13560845959237622,0.4522133253996353,1.8285620188685285,-0.6429435893726733,1.448448785568869,1.0675480922862204,0.2112417984925894,-0.3341478103334249,4.917492659435559,-0.4152809195710186,0.7039155427404739,-0.6850808626505676,0.304783521666528,-1.3707038556261375,1.4159992226041558,0.6684312487998063,-0.43569894708233464,0.5249283688242936,1.1853076769616102,0.8963828986355812,0.34189565270391015,0.19240090545282404,0.24879026863223094,-0.23391832955023042,0.8443364414586735,4.496083243944842,-0.09573868680970035,-1.0309922696079223,0.4339317726253653,1.10136302234031,-1.32448279287036,1.6088736896093438,-0.4561715837491249,0.41560864305026346,-0.13496893733397167,-0.15465833406450158,0.6327920744221581,0.15458450029912923,0.05924575850806966,0.09751936170847361,-0.31399754246940065,0.6149138846414414,-0.7062381065178011,0.0784057608191252,0.3972437030547652,-0.1743976571717926,-0.3746072665047304,-0.09573868680970035,-0.13496893733397167,1.448448785568869,0.37883671691997084,0.6861926522306766,-1.0531559749508097,1.0335956619699211,-0.017863872838918923,1.1182193515975896,0.9308994066578831,0.19240090545282404,-0.5179207785497725,0.37883671691997084,1.7507404107076854,-1.8749638166066318,1.2186519515565648,0.6149138846414414,1.0844726591413512,-0.21402733728023318,0.7216001253197305,0.04003907639528579,1.0844726591413512,2.10311335779798,0.7392466032253644,-1.0976844720755563,1.4646273575456767,1.1350418152893942,1.7194151890935954,0.001484545851543285,0.6506311257033517,-0.07619722251063903,1.1685858128764244,2.3108961338926965,2.920606361818982,-0.27385423081555665,0.8269144177911181,1.9210387080998343,0.23003816681518965,1.4807753146449134,0.5249283688242936,3.1642440468955613,0.19240090545282404,-0.1743976571717926,0.37883671691997084,0.4886526246803302,0.304783521666528,5.246740467606561,1.5129799522193979,0.0784057608191252,-0.7062381065178011,1.2019963358891592,1.2518646944415734,-0.7487318629297377,-0.25386051882213734,0.23003816681518965,1.3343293891978911,0.4339317726253653,2.8655806296701516,0.04003907639528579,1.9056938106121482,-0.2938997945656019,0.09751936170847361,-0.23391832955023042,0.2861626937330696,-0.017863872838918923,1.4159992226041558,2.3839446526313073,-0.2938997945656019,4.212879893636516,-2.285109634377232,0.36038744680166185,0.4522133253996353,0.13560845959237622,2.2962144810512832,3.1642440468955613,0.999504346348033,-0.3543509374216771,0.020785433429236007,0.6506311257033517,0.17351522707522676,-0.4561715837491249,1.5290369140825837,0.5790392392161661,3.2440577254623797,0.11658683691935393,0.9481038780076505,0.19240090545282404,0.7216001253197305,1.5290369140825837,-1.3014824482535676,0.999504346348033,1.1182193515975896
| 3,425
|
Transmembrane transport
| 90
| 231
| 4.393962
| 0.000011
|
P03915,O60830,Q99595,Q9UHG3,P21796,Q7KZN9,P45880,Q9NS69,Q6P4A7,P24539,Q9Y584,Q96H78,Q9UDW1,Q13423,O95831,O75964,P30825,Q8NE01,Q8WTV0,Q9UJS0,Q9C0H2,P04062,P53985,Q15629,Q6NUK1,O00400,Q15041,P61421,Q9NQ11,Q8TB61,Q9UBX3,Q16611,P00846,Q70HW3,O43772,P31751,Q96GC9,O75844,Q9H2D1,P49840,P33527,P12236,Q99523,P23786,Q5T1Q4,Q8N4V1,P51790,Q9Y619,Q9Y277,Q99797,Q96ES6,Q8IXU6,Q03519,P20020,Q96AQ8,Q9HD20,Q9BZF1,Q9BSK2,Q9NRA0,Q6NT16,P05067,Q9BQT8,P35670,Q8NEW0,Q8N1S5,P08183,Q06787,Q15043,P49755,O14925,Q6NXT4,Q6PML9,P20674,P07384,Q14728,Q9UGP8,Q9Y6M7,O95202,O75298,O60831,Q15388,Q96PU5,Q8IYU8,P46934,P36383,P50416,P41440,P12235,Q9HD47,P11413
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
507,2,1,4,5,529,14,18,538,547,44,47,48,560,557,56,571,582,64,586,70,80,591,84,604,86,601,600,101,109,111,629,121,133,143,653,676,154,157,667,666,664,686,170,183,186,204,221,220,223,231,233,236,235,240,244,261,288,290,300,297,305,307,314,327,322,324,335,343,340,348,349,353,352,366,389,390,382,403,402,416,417,426,423,430,449,458,469,503,494
|
738,2237,2315,86,1622,931,1528,340,2514,740,1237,143,813,814,2239,2,402,1833,3196,2186,403,1577,2890,1140,154,2150,1496,56,1380,382,2993,557,1457,914,121,507,80,916,1533,297,949,2320,1178,1704,352,1751,2946,322,2151,1211,2923,1753,3182,1274,494,469,664,762,1101,724,1313,3020,2849,235,353,982,2104,3304,5,170,547,2851,1103,2950,871,3132,873,571,693,653,2326,2327,666,307,430,839,1008,934,1841,458,14,423,1464,1544,3204,343,667,449,745,204,725,1674,591,1248,2657,1067,1249,1185,2658,2570,600,2900,1041,937,780,1721,2203,1550,1640,236,1109,3166,324,798,3298,1505,560,1551,366,1393,601,335,2395,416,84,1015,1075,629,749,959,799,183,300,604,348,1814,538,1291,349,2495,941,133,529,3256,1727,233,426,327,1440,186,582,1509,314,109,684,3109,64,1117,1975,240,825,964,231,676,47,1926,1022,417,1735,1514,2834,686,1,1566,223,1230,3040,1403,305,288,2965,968,1001,261,70,1299,2673,157,1820,1201,1883,2368,907,1406,244,1330,503,101,290,2044,18,3406,834,2794,111,48,389,1825,4,1339,586,1412,1056,220,809,1169,1621,44,221,3333,390
|
0.4339317726253653,-0.39491714390968624,-0.43569894708233464,2.5425880302168293,-0.13496893733397167,0.24879026863223094,-0.09573868680970035,1.10136302234031,-0.5179207785497725,0.4339317726253653,0.05924575850806966,1.9973622966526008,0.36038744680166185,0.36038744680166185,-0.39491714390968624,5.203448495367863,0.9481038780076505,-0.23391832955023042,-1.0309922696079223,-0.3746072665047304,0.9481038780076505,-0.11532915716857117,-0.7062381065178011,0.11658683691935393,1.9056938106121482,-0.3543509374216771,-0.07619722251063903,3.0567507737172264,-0.017863872838918923,0.999504346348033,-0.79146743676524,0.6861926522306766,-0.056704463496115395,0.2674983597767239,2.162978192726338,0.7744260494954054,2.62795906725318,0.2674983597767239,-0.09573868680970035,1.2186519515565648,0.23003816681518965,-0.43569894708233464,0.09751936170847361,-0.1743976571717926,1.0675480922862204,-0.19418721956236745,-0.7487318629297377,1.1350418152893942,-0.3543509374216771,0.0784057608191252,-0.7274549681465066,-0.19418721956236745,-1.00889493373649,0.04003907639528579,0.7919594158846363,0.8269144177911181,0.5249283688242936,0.41560864305026346,0.13560845959237622,0.4522133253996353,0.020785433429236007,-0.8129269700518783,-0.6850808626505676,1.448448785568869,1.0675480922862204,0.2112417984925894,-0.3341478103334249,-1.2102024240548812,4.917492659435559,1.813053367361717,0.7039155427404739,-0.6850808626505676,0.13560845959237622,-0.7487318629297377,0.304783521666528,-0.9211596241735596,0.304783521666528,0.6684312487998063,0.4886526246803302,0.5430054701796704,-0.43569894708233464,-0.43569894708233464,0.5249283688242936,1.1853076769616102,0.8963828986355812,0.34189565270391015,0.19240090545282404,0.24879026863223094,-0.23391832955023042,0.8443364414586735,4.496083243944842,0.9136591415130947,-0.056704463496115395,-0.09573868680970035,-1.0309922696079223,1.10136302234031,0.5249283688242936,0.8617217363584101,0.4339317726253653,1.6088736896093438,0.4522133253996353,-0.15465833406450158,0.6327920744221581,0.05924575850806966,-0.5801746865595289,0.15458450029912923,0.05924575850806966,0.09751936170847361,-0.5801746865595289,-0.5386155010309926,0.6149138846414414,-0.7062381065178011,0.17351522707522676,0.24879026863223094,0.3972437030547652,-0.1743976571717926,-0.3746072665047304,-0.09573868680970035,-0.13496893733397167,1.448448785568869,0.13560845959237622,-0.9648974270030561,1.1350418152893942,0.37883671691997084,-1.1875599920679472,-0.07619722251063903,0.6861926522306766,-0.09573868680970035,1.0335956619699211,-0.017863872838918923,0.6149138846414414,1.1182193515975896,-0.4561715837491249,0.9308994066578831,2.599591402744298,0.19240090545282404,0.15458450029912923,0.5790392392161661,0.4339317726253653,0.23003816681518965,0.37883671691997084,1.7507404107076854,1.2186519515565648,0.6149138846414414,1.0844726591413512,-0.21402733728023318,0.7216001253197305,0.04003907639528579,1.0844726591413512,-0.4972821326535668,0.24879026863223094,2.10311335779798,0.7392466032253644,-1.0976844720755563,-0.1743976571717926,1.4646273575456767,0.9136591415130947,1.1350418152893942,-0.03726011192253851,1.7194151890935954,0.6506311257033517,-0.07619722251063903,1.1685858128764244,2.3108961338926965,0.5068108281574367,-0.8776777826591424,2.920606361818982,0.13560845959237622,-0.27385423081555665,1.4322394553880162,0.36038744680166185,0.23003816681518965,1.4807753146449134,0.5249283688242936,3.1642440468955613,-0.25386051882213734,0.19240090545282404,0.9308994066578831,-0.1743976571717926,-0.07619722251063903,-0.663982825714329,0.5068108281574367,5.246740467606561,-0.09573868680970035,1.5129799522193979,0.0784057608191252,-0.8129269700518783,-0.017863872838918923,1.2019963358891592,1.2518646944415734,-0.7487318629297377,0.23003816681518965,0.2112417984925894,1.3343293891978911,2.8655806296701516,0.04003907639528579,-0.5801746865595289,1.9056938106121482,-0.21402733728023318,0.09751936170847361,-0.23391832955023042,-0.43569894708233464,0.2861626937330696,-0.017863872838918923,1.4159992226041558,0.020785433429236007,0.7919594158846363,2.3839446526313073,1.2518646944415734,-0.2938997945656019,4.212879893636516,-2.285109634377232,0.36038744680166185,-0.6429435893726733,2.2962144810512832,3.1642440468955613,0.999504346348033,-0.21402733728023318,5.094411977540183,0.020785433429236007,0.6506311257033517,-0.017863872838918923,0.17351522707522676,1.5290369140825837,0.37883671691997084,0.11658683691935393,-0.11532915716857117,3.2440577254623797,1.5290369140825837,-1.3014824482535676,0.999504346348033
| 3,425
|
Transporter
| 88
| 216
| 4.0467
| 0.000052
|
Q15070,P24390,Q9BQE5,Q9Y5P4,Q9NZJ7,P24539,Q9Y584,Q96H78,P30825,Q9UJS0,Q6NUK4,P53985,Q6NUK1,O00400,Q99805,Q15363,P61421,Q8TB61,Q9UBX3,Q9Y6C9,Q9Y487,O14972,P00846,Q70HW3,Q9NV70,O43772,Q9P2W9,Q9H2D1,Q8TEX9,P33527,P12236,O95721,P17900,Q99523,Q8TBP6,Q9UEU0,Q5T1Q4,O00471,O60749,P52294,Q96AX1,Q9NZD2,Q9Y619,P16615,O60499,Q96ES6,Q8IXU6,Q92544,Q03519,P20020,O75436,P48739,P56962,Q9Y3A6,Q9Y296,Q9H6H4,O15155,Q8N1F7,Q9Y3B3,Q9BSK2,Q92973,Q6NT16,O95249,Q9BQT8,P35670,Q8NEW0,Q8N1S5,P49257,P08183,Q12907,Q15043,P49755,Q6NXT4,Q6PML9,Q9HD45,Q9Y6M7,O15321,O00505,O95202,O43752,Q15388,O00560,P57740,P41440,Q93050,P12235,O43760,Q12768
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
520,12,20,544,552,547,44,47,571,586,581,591,604,86,606,93,600,109,111,635,634,117,121,133,657,143,153,157,673,666,664,663,166,686,684,706,183,689,690,205,209,736,221,724,225,231,233,753,236,235,741,743,249,253,793,787,776,279,284,288,286,300,303,305,307,314,327,323,322,334,335,343,348,349,362,390,378,377,382,379,416,419,436,458,473,469,481,498
|
3157,2237,2886,86,689,377,419,946,2600,3171,117,1746,776,378,1747,2514,379,481,143,813,225,1136,1831,690,1238,1833,741,1140,1496,3181,2278,382,303,2845,2419,1245,663,1457,121,916,1533,949,1178,322,2151,1099,837,1274,950,469,664,795,724,166,235,982,2104,12,547,2851,871,872,571,666,1351,307,839,1277,1841,458,1905,743,323,343,1247,819,1010,205,1674,2519,2898,1184,591,2811,2199,2657,1546,1067,3217,1249,1185,249,436,600,2900,2157,3117,2158,780,1721,2699,898,1550,1640,236,2340,1434,498,1435,2957,334,1284,2780,2619,1852,1320,335,520,2534,2395,93,416,1015,183,3394,300,604,581,348,1814,349,133,1158,1116,1326,233,279,327,314,2082,2131,109,684,2084,673,1198,1866,753,1729,286,473,1119,209,2584,231,47,1734,1022,1735,1263,1400,686,889,606,1230,20,305,2226,288,2460,968,1518,1299,1568,1479,157,787,1201,1883,907,1406,362,2044,1333,657,1027,736,552,2270,2369,1783,153,2232,1486,111,706,944,1339,1695,586,973,2640,1451,793,253,284,634,44,1170,1031,1660,544,221,1452,635,390
|
-0.9648974270030561,-0.39491714390968624,-0.7062381065178011,2.5425880302168293,0.4886526246803302,0.999504346348033,0.9136591415130947,0.23003816681518965,-0.5593666767876478,-0.9868634800659423,2.2224410858737813,-0.19418721956236745,0.3972437030547652,0.999504346348033,-0.19418721956236745,-0.5179207785497725,0.999504346348033,0.8094554736885617,1.9973622966526008,0.36038744680166185,1.4968927991314636,0.11658683691935393,-0.23391832955023042,0.4886526246803302,0.05924575850806966,-0.23391832955023042,0.4339317726253653,0.11658683691935393,-0.07619722251063903,-1.00889493373649,-0.4152809195710186,0.999504346348033,1.2019963358891592,-0.6850808626505676,-0.4766991906424338,0.05924575850806966,0.5249283688242936,-0.056704463496115395,2.162978192726338,0.2674983597767239,-0.09573868680970035,0.23003816681518965,0.09751936170847361,1.1350418152893942,-0.3543509374216771,0.13560845959237622,0.34189565270391015,0.04003907639528579,0.23003816681518965,0.8269144177911181,0.5249283688242936,0.37883671691997084,0.4522133253996353,1.8285620188685285,1.448448785568869,0.2112417984925894,-0.3341478103334249,4.5656364088713355,0.7039155427404739,-0.6850808626505676,0.304783521666528,0.304783521666528,0.6684312487998063,0.5249283688242936,0.001484545851543285,1.1853076769616102,0.34189565270391015,0.04003907639528579,-0.23391832955023042,0.8443364414586735,-0.25386051882213734,0.4339317726253653,1.1350418152893942,1.10136302234031,0.05924575850806966,0.36038744680166185,0.19240090545282404,1.6088736896093438,-0.15465833406450158,-0.5179207785497725,-0.7062381065178011,0.09751936170847361,0.6327920744221581,-0.663982825714329,-0.3746072665047304,-0.5801746865595289,-0.09573868680970035,0.15458450029912923,-1.0531559749508097,0.05924575850806966,0.09751936170847361,1.3834254662027163,0.8790704925764257,0.6149138846414414,-0.7062381065178011,-0.3543509374216771,-0.8993869388026995,-0.3543509374216771,0.3972437030547652,-0.1743976571717926,-0.6010399151957811,0.2861626937330696,-0.09573868680970035,-0.13496893733397167,1.448448785568869,-0.43569894708233464,-0.03726011192253851,0.7919594158846363,-0.03726011192253851,-0.7487318629297377,1.1182193515975896,0.04003907639528579,-0.6429435893726733,-0.5593666767876478,-0.23391832955023042,0.020785433429236007,1.1182193515975896,0.7568551780007351,-0.5179207785497725,-0.4561715837491249,2.4564023437522535,0.9308994066578831,0.19240090545282404,1.7507404107076854,-1.8749638166066318,1.2186519515565648,0.6149138846414414,0.6506311257033517,1.0844726591413512,-0.21402733728023318,1.0844726591413512,2.10311335779798,0.11658683691935393,0.13560845959237622,0.020785433429236007,1.4646273575456767,1.2849471759441964,1.1350418152893942,1.1685858128764244,-0.31399754246940065,-0.3341478103334249,2.3108961338926965,0.5068108281574367,-0.31399754246940065,0.5249283688242936,0.09751936170847361,-0.23391832955023042,0.4339317726253653,-0.1743976571717926,1.2518646944415734,0.8269144177911181,0.13560845959237622,1.5610608196920086,-0.5386155010309926,1.4807753146449134,3.1642440468955613,-0.1743976571717926,0.19240090545282404,-0.1743976571717926,0.05924575850806966,-0.017863872838918923,0.5068108281574367,0.304783521666528,0.6149138846414414,0.0784057608191252,4.007216364080601,1.2019963358891592,-0.3746072665047304,1.2518646944415734,-0.4766991906424338,0.23003816681518965,-0.07619722251063903,0.04003907639528579,-0.09573868680970035,-0.056704463496115395,1.9056938106121482,0.3972437030547652,0.09751936170847361,-0.23391832955023042,0.2861626937330696,-0.017863872838918923,1.0505891507074792,-0.2938997945656019,0.020785433429236007,0.5430054701796704,0.19240090545282404,0.4522133253996353,0.7039155427404739,-0.39491714390968624,-0.43569894708233464,-0.19418721956236745,1.9210387080998343,-0.3746072665047304,-0.056704463496115395,2.2962144810512832,0.4886526246803302,0.24879026863223094,0.020785433429236007,-0.15465833406450158,0.6506311257033517,0.23003816681518965,-0.5593666767876478,-0.03726011192253851,0.3972437030547652,1.3670916483246272,1.268422139234549,0.5790392392161661,3.2440577254623797,0.11658683691935393,0.19240090545282404,-0.13496893733397167,0.7216001253197305,1.5290369140825837,-0.03726011192253851,0.5790392392161661,0.999504346348033
| 3,425
|
Lysosomal lumen
| 21
| 37
| 4.021952
| 0.000058
|
P16278,P06280,Q14108,P50897,Q13510,Q9UM22,P11117,P17900,O00584,Q8NHP8,O43681,Q9UMR5,P54802,P07602,Q8IV08,P04062,P15586,O14773,Q9NQ11,P10619,P06865
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
10,139,13,16,17,169,165,166,164,45,311,59,202,77,79,80,345,89,101,114,384
|
164,2761,89,311,80,576,139,384,77,1750,1665,421,114,165,1835,795,3377,345,10,166,934,3289,2014,16,202,1218,17,13,79,2453,45,718,2039,101,552,169,59
|
1.8285620188685285,-0.6429435893726733,2.5139509284160675,1.1685858128764244,2.62795906725318,0.6506311257033517,2.057946899190213,0.999504346348033,2.7125341584739417,-0.19418721956236745,-0.15465833406450158,0.9136591415130947,2.2667784467407786,1.8285620188685285,-0.23391832955023042,0.37883671691997084,-1.6303721469296955,1.0844726591413512,4.600231735570217,1.8285620188685285,0.24879026863223094,-1.1649875074107834,-0.2938997945656019,4.33187072621963,1.6247523908291193,0.0784057608191252,4.3200361894985715,4.530920591223999,2.6703449638891956,-0.4766991906424338,3.230802708999954,0.4704535329188798,-0.2938997945656019,2.3839446526313073,0.7039155427404739,1.8285620188685285,3.002533477096661
| 3,425
|
Intrinsic component of organelle membrane
| 77
| 157
| 3.99797
| 0.000064
|
Q99595,O60830,Q15070,Q9Y282,P30511,Q6P4A7,Q5XKP0,Q8NBI6,Q9Y2R0,Q9P035,Q13505,Q9H9P8,Q86XL3,Q15629,Q9UKV5,Q9NZ01,Q15041,O15118,Q9NQ11,Q9BUR5,Q9BUB7,O43505,P42892,Q8TB61,Q6ZRP7,O95470,Q16611,Q9Y4P3,Q15125,O75844,Q8N4V1,Q6Y1H2,O76024,Q6UXV4,Q9NX63,Q9H3K2,O43819,Q9NQC3,Q86YN1,O60499,Q9Y512,Q9GZP9,Q03519,P20020,Q96AQ8,Q15006,L0R6Q1,Q5BJH7,O94901,Q9UG56,Q8N8Q8,O15155,P98194,Q14739,Q9Y5Z9,P13473,Q96S52,Q16134,Q9NWR8,Q5J8M3,O43808,O43402,P50336,O14925,Q9BWH2,O43752,P10321,O75298,Q15388,O95070,Q8IWA4,P49069,Q96A33,P50416,P12235,O43292,P57105
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,2,520,24,28,538,561,562,54,585,73,597,78,84,610,94,601,97,101,621,620,104,107,109,631,118,629,679,151,154,186,697,691,696,195,720,709,210,212,225,761,227,236,235,240,748,738,247,263,791,272,776,780,281,810,795,829,304,834,821,813,812,818,340,388,379,396,403,416,413,433,431,441,449,469,480,483
|
1489,738,1006,340,1746,97,2918,776,1346,480,812,104,379,813,709,225,2,947,403,1172,154,1175,691,894,1380,263,413,913,118,1457,1900,2804,1311,396,469,795,235,1062,3174,2246,2951,28,3249,107,431,818,449,2610,1247,920,877,483,1430,2900,780,1721,1640,236,989,1110,73,2075,281,748,601,520,151,1853,416,84,304,629,2077,820,2662,247,1596,821,900,561,882,538,696,697,631,1726,78,1326,212,433,3256,1862,2218,186,1771,272,562,1605,1509,1362,109,2713,2300,1048,1924,1079,441,240,964,1022,829,1514,1,1403,1931,1690,620,1083,621,388,2937,227,2366,2835,720,2588,1883,597,1406,2142,1372,101,210,2044,1653,834,195,94,585,3089,2839,972,791,1130,1004,610,1056,24,54,1235,892,679,1621,761,1661,810,975
|
-0.07619722251063903,0.4339317726253653,0.19240090545282404,1.10136302234031,-0.19418721956236745,2.3984830795821077,-0.7274549681465066,0.3972437030547652,0.001484545851543285,0.8094554736885617,0.36038744680166185,2.340187200505293,0.999504346348033,0.36038744680166185,0.4704535329188798,1.4968927991314636,5.203448495367863,0.23003816681518965,0.9481038780076505,0.09751936170847361,1.9056938106121482,0.09751936170847361,0.4886526246803302,0.2861626937330696,-0.017863872838918923,1.3179006469481906,0.9308994066578831,0.2674983597767239,2.2224410858737813,-0.056704463496115395,-0.25386051882213734,-0.663982825714329,0.020785433429236007,0.9652727380057537,0.8269144177911181,0.37883671691997084,1.448448785568869,0.15458450029912923,-0.9868634800659423,-0.39491714390968624,-0.7487318629297377,3.6205514552672318,-1.0976844720755563,2.325553674617119,0.8963828986355812,0.36038744680166185,0.8617217363584101,-0.5593666767876478,0.05924575850806966,0.2674983597767239,0.304783521666528,0.8094554736885617,-0.03726011192253851,-0.7062381065178011,0.3972437030547652,-0.1743976571717926,-0.13496893733397167,1.448448785568869,0.2112417984925894,0.13560845959237622,2.8379436574544386,-0.31399754246940065,1.268422139234549,0.4339317726253653,0.6149138846414414,0.7568551780007351,1.9210387080998343,-0.23391832955023042,0.9308994066578831,2.599591402744298,1.2019963358891592,0.5790392392161661,-0.31399754246940065,0.36038744680166185,-0.5801746865595289,1.3997279417347968,-0.11532915716857117,0.36038744680166185,0.2861626937330696,0.6861926522306766,0.304783521666528,0.7216001253197305,0.4886526246803302,0.4886526246803302,0.5790392392161661,-0.1743976571717926,2.6703449638891956,0.020785433429236007,1.5450638238651857,0.8963828986355812,-1.0976844720755563,-0.23391832955023042,-0.3746072665047304,1.7194151890935954,-0.19418721956236745,1.3014399603266282,0.6861926522306766,-0.11532915716857117,-0.07619722251063903,0.001484545851543285,2.3108961338926965,-0.6010399151957811,-0.4152809195710186,0.17351522707522676,-0.25386051882213734,0.15458450029912923,0.8790704925764257,1.4322394553880162,0.23003816681518965,0.19240090545282404,0.36038744680166185,-0.07619722251063903,5.246740467606561,-0.017863872838918923,-0.25386051882213734,-0.15465833406450158,0.5969963442295187,0.15458450029912923,0.5969963442295187,0.999504346348033,-0.7274549681465066,1.4968927991314636,-0.43569894708233464,-0.663982825714329,0.4704535329188798,-0.5386155010309926,-0.23391832955023042,0.6327920744221581,-0.017863872838918923,-0.3341478103334249,0.001484545851543285,2.3839446526313073,1.5610608196920086,-0.2938997945656019,-0.13496893733397167,0.36038744680166185,1.6879761304662688,2.4564023437522535,0.6506311257033517,-0.8560317012161593,-0.663982825714329,0.23003816681518965,0.3972437030547652,0.13560845959237622,0.2112417984925894,0.6149138846414414,0.17351522707522676,3.709233648956977,3.097206606706352,0.0784057608191252,0.304783521666528,0.5249283688242936,-0.11532915716857117,0.4339317726253653,-0.13496893733397167,0.37883671691997084,0.23003816681518965
| 3,425
|
Mitochondrion organization
| 78
| 212
| 3.882796
| 0.000103
|
P03915,Q99595,O60830,P21796,Q15070,Q69YU5,P45880,Q9NS69,Q9Y5P4,P30419,O43676,Q9NUQ9,Q5XKP0,Q9Y584,O95831,Q9Y2R0,O75153,Q96CU9,P03886,Q13505,Q9H4A6,P04062,Q9NQ11,Q9BUR5,Q9BUB7,Q9H061,Q9Y6C9,Q16611,Q9NVI7,P27544,O96000,P50851,Q8N4H5,Q7L592,P49840,O75306,Q96A26,O00165,P55786,Q6DKK2,Q9Y5J7,Q6UXV4,Q9NX63,P31749,Q9H3K2,P02786,O43819,Q9Y375,Q10713,P52789,Q99797,P14406,O14737,P30536,O95429,Q8N8Q8,Q9BSK2,Q9NW81,Q9UDX5,P49257,Q9Y241,Q9Y6M9,O43674,O14925,Q16543,Q9BWH2,O95202,O95167,Q9Y5J9,Q86Y39,Q15388,Q8IWA4,O95168,Q5JRX3,Q9BRT2,P12235,O60313,Q9Y2S7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
507,1,2,5,520,8,14,18,544,549,39,42,561,44,557,54,61,68,69,73,596,80,101,621,620,105,635,629,647,125,637,639,150,672,667,173,174,680,182,185,188,696,195,693,720,710,709,737,727,725,223,232,234,242,245,272,288,315,331,323,338,339,341,340,347,388,382,381,411,409,416,433,445,460,476,469,482,513
|
680,1092,2886,3408,1306,931,234,340,1418,777,740,341,39,1748,709,482,2,1456,61,1996,2186,173,1172,2890,1897,1173,1175,1380,1244,913,381,445,1382,382,2478,2604,245,2376,557,637,1457,1901,710,69,507,80,3362,2805,949,1665,1424,2891,3182,1100,469,232,2771,5,125,2950,3344,2324,3132,549,242,693,2652,2732,1539,3201,1587,3249,2483,14,1544,1104,323,667,779,1959,639,1247,2385,725,746,182,2067,1011,2337,2523,2022,2203,2488,727,1250,73,1913,520,1810,416,2577,347,629,1016,2535,820,2869,959,2662,1596,460,1156,1968,561,8,185,696,1919,672,1602,2665,409,884,433,1862,2218,2452,3125,3156,150,1440,1648,272,1509,1362,2132,3109,1117,1974,174,68,825,1563,1608,999,1263,1000,1930,1688,2834,1736,1,1566,2632,223,1367,476,288,620,2137,621,388,2754,2366,2835,105,1123,720,596,2756,2368,101,970,18,1408,42,1653,647,891,315,3072,1300,3011,195,2309,1128,2410,331,791,1130,2178,2094,1412,338,1888,54,513,1657,737,1524,892,2883,1621,761,44,1170,188,411,911,544,635,339
|
0.5068108281574367,0.13560845959237622,-0.7062381065178011,-2.4725910422416124,0.020785433429236007,0.24879026863223094,1.448448785568869,1.10136302234031,-0.03726011192253851,0.3972437030547652,0.4339317726253653,1.10136302234031,3.33632142390138,-0.19418721956236745,0.4704535329188798,0.8094554736885617,5.203448495367863,-0.056704463496115395,2.9616608605918957,-0.2938997945656019,-0.3746072665047304,1.7975170034836079,0.09751936170847361,-0.7062381065178011,-0.25386051882213734,0.09751936170847361,0.09751936170847361,-0.017863872838918923,0.05924575850806966,0.2674983597767239,0.999504346348033,0.8617217363584101,-0.017863872838918923,0.999504346348033,-0.4972821326535668,-0.5593666767876478,1.3997279417347968,-0.4561715837491249,0.6861926522306766,0.5610423537706956,-0.056704463496115395,-0.25386051882213734,0.4704535329188798,2.8655806296701516,0.7744260494954054,2.62795906725318,-1.5111725380859105,-0.663982825714329,0.23003816681518965,-0.15465833406450158,-0.03726011192253851,-0.7062381065178011,-1.00889493373649,0.13560845959237622,0.8269144177911181,1.4646273575456767,-0.6429435893726733,4.917492659435559,2.133096436106864,-0.7487318629297377,-1.3707038556261375,-0.43569894708233464,-0.9211596241735596,0.7039155427404739,1.4159992226041558,0.4886526246803302,-0.5801746865595289,-0.6219627517160322,-0.09573868680970035,-1.0309922696079223,-0.11532915716857117,-1.0976844720755563,-0.4972821326535668,4.496083243944842,-0.09573868680970035,0.13560845959237622,1.1350418152893942,0.5249283688242936,0.3972437030547652,-0.27385423081555665,0.5610423537706956,0.05924575850806966,-0.4561715837491249,0.4522133253996353,0.4339317726253653,1.7507404107076854,-0.31399754246940065,0.19240090545282404,-0.43569894708233464,-0.5179207785497725,-0.2938997945656019,-0.3746072665047304,-0.4972821326535668,0.4522133253996353,0.05924575850806966,2.8379436574544386,-0.25386051882213734,0.7568551780007351,-0.21402733728023318,0.9308994066578831,-0.5386155010309926,1.0844726591413512,0.5790392392161661,0.19240090545282404,-0.5179207785497725,0.36038744680166185,-0.6850808626505676,0.23003816681518965,-0.5801746865595289,-0.11532915716857117,0.8443364414586735,0.11658683691935393,-0.27385423081555665,0.6861926522306766,4.669065000725359,1.7194151890935954,0.4886526246803302,-0.25386051882213734,0.5249283688242936,-0.11532915716857117,-0.5801746865595289,0.9481038780076505,0.304783521666528,0.8963828986355812,-0.23391832955023042,-0.3746072665047304,-0.4766991906424338,-0.8993869388026995,-0.9429962985415629,1.95164797870373,-0.03726011192253851,-0.13496893733397167,1.3014399603266282,-0.07619722251063903,0.001484545851543285,-0.3341478103334249,-0.8776777826591424,0.13560845959237622,-0.27385423081555665,1.7975170034836079,2.879367974649712,0.36038744680166185,-0.09573868680970035,-0.11532915716857117,0.2112417984925894,0.05924575850806966,0.2112417984925894,-0.25386051882213734,-0.15465833406450158,-0.663982825714329,-0.1743976571717926,5.246740467606561,-0.09573868680970035,-0.5593666767876478,1.5129799522193979,0.001484545851543285,0.8269144177911181,1.2518646944415734,0.5969963442295187,-0.3341478103334249,0.5969963442295187,0.999504346348033,-0.6219627517160322,-0.43569894708233464,-0.663982825714329,2.340187200505293,0.13560845959237622,0.4704535329188798,0.6327920744221581,-0.6219627517160322,-0.43569894708233464,2.3839446526313073,0.23003816681518965,4.212879893636516,-0.017863872838918923,3.2705115690490496,-0.13496893733397167,0.5610423537706956,0.304783521666528,1.1685858128764244,-0.8344482451084184,0.04003907639528579,-0.79146743676524,1.6879761304662688,-0.4152809195710186,0.13560845959237622,-0.4561715837491249,1.1350418152893942,0.3972437030547652,0.13560845959237622,-0.3543509374216771,-0.31399754246940065,-0.017863872838918923,1.1182193515975896,-0.23391832955023042,3.097206606706352,0.7744260494954054,-0.13496893733397167,0.4522133253996353,-0.07619722251063903,0.304783521666528,-0.6850808626505676,-0.11532915716857117,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696,0.7216001253197305,0.5790392392161661,1.1182193515975896
| 3,425
|
Transport of small molecules
| 45
| 163
| 3.686276
| 0.000228
|
P35613,O95202,P21796,Q70HW3,P45880,Q9UNS2,P30519,P49721,P61289,P28072,Q96PU5,P10644,Q8IYU8,P40855,Q15904,P35670,Q8NEW0,Q8N4V1,P60900,Q8WTV0,P28074,Q9C0H2,P08183,P51790,P28070,P20618,Q15043,Q9UBV2,Q5EBL8,O00400,Q9Y277,Q93050,Q6NXT4,P12235,Q99797,O15118,Q9GZP9,Q9NQ11,P09601,Q9UL46,Q8TB61,Q9UBX3,P20020,Q9HD20,Q9Y6M7
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
254,382,5,133,14,410,21,23,404,26,417,163,426,422,177,307,314,186,190,64,448,70,322,204,206,208,335,337,459,86,220,473,348,469,223,97,227,101,102,363,109,111,235,244,390
|
575,3015,86,1490,2681,97,2514,978,1833,2890,980,1173,3159,1898,1579,382,2764,710,916,1533,949,1794,613,322,2151,1099,102,163,1274,469,664,2481,724,1313,3020,2242,235,2103,208,982,2104,1536,5,2383,1348,1064,2692,1103,2425,206,26,448,871,21,873,571,666,1539,1540,1180,1801,254,307,2977,1315,1008,3289,1841,422,2334,14,896,1353,23,1716,204,1184,591,2657,1067,2612,3059,920,190,404,600,1218,1759,2201,2614,2158,1909,1186,780,2698,2699,955,727,2024,3254,3102,1764,1189,2492,335,1015,177,799,459,348,1814,133,2785,3256,426,186,2786,1509,314,109,64,1117,490,2543,473,2934,417,1735,1930,605,2172,926,1566,223,1230,1403,2227,1083,70,227,1299,1123,1820,1201,244,101,2044,834,1375,337,111,2177,2370,1339,1412,363,1522,410,220,634,1621,1031,390
|
0.6506311257033517,-0.8129269700518783,2.5425880302168293,-0.07619722251063903,-0.6010399151957811,2.3984830795821077,-0.5179207785497725,0.2112417984925894,-0.23391832955023042,-0.7062381065178011,0.2112417984925894,0.09751936170847361,-0.9648974270030561,-0.25386051882213734,-0.11532915716857117,0.999504346348033,-0.6429435893726733,0.4704535329188798,0.2674983597767239,-0.09573868680970035,0.23003816681518965,-0.21402733728023318,0.5969963442295187,1.1350418152893942,-0.3543509374216771,0.13560845959237622,2.3693825937809168,1.844043079409893,0.04003907639528579,0.8269144177911181,0.5249283688242936,-0.4972821326535668,0.4522133253996353,0.020785433429236007,-0.8129269700518783,-0.39491714390968624,1.448448785568869,-0.3341478103334249,1.5610608196920086,0.2112417984925894,-0.3341478103334249,-0.09573868680970035,4.917492659435559,-0.4561715837491249,0.001484545851543285,0.15458450029912923,-0.6010399151957811,0.13560845959237622,-0.4766991906424338,1.592965616941986,3.6839797644624737,0.8617217363584101,0.304783521666528,3.921251120524279,0.304783521666528,0.6684312487998063,0.5249283688242936,-0.09573868680970035,-0.09573868680970035,0.09751936170847361,-0.21402733728023318,1.3507263392996962,1.1853076769616102,-0.7700692108929594,0.020785433429236007,0.19240090545282404,-1.1649875074107834,-0.23391832955023042,0.9136591415130947,-0.43569894708233464,4.496083243944842,0.2861626937330696,0.001484545851543285,3.734421078054943,-0.1743976571717926,1.6088736896093438,0.09751936170847361,0.6327920744221581,-0.5801746865595289,0.15458450029912923,-0.5593666767876478,-0.8344482451084184,0.2674983597767239,1.703709953072957,0.9481038780076505,0.6149138846414414,0.0784057608191252,-0.19418721956236745,-0.3746072665047304,-0.5593666767876478,-0.3543509374216771,-0.25386051882213734,0.09751936170847361,0.3972437030547652,-0.6010399151957811,-0.6010399151957811,0.23003816681518965,0.4522133253996353,-0.2938997945656019,-1.0976844720755563,-0.8776777826591424,-0.19418721956236745,0.09751936170847361,-0.4972821326535668,1.1182193515975896,0.19240090545282404,1.7819528049746483,0.37883671691997084,0.8443364414586735,1.0844726591413512,-0.21402733728023318,2.10311335779798,-0.6429435893726733,-1.0976844720755563,0.9136591415130947,1.7194151890935954,-0.6429435893726733,-0.07619722251063903,1.1685858128764244,2.3108961338926965,2.920606361818982,0.13560845959237622,0.8094554736885617,-0.5179207785497725,0.8269144177911181,-0.7274549681465066,0.9308994066578831,-0.1743976571717926,-0.25386051882213734,0.6149138846414414,-0.3543509374216771,0.2674983597767239,-0.09573868680970035,1.5129799522193979,0.0784057608191252,-0.017863872838918923,-0.3746072665047304,0.15458450029912923,2.8655806296701516,1.4968927991314636,0.04003907639528579,0.13560845959237622,-0.21402733728023318,0.09751936170847361,1.4159992226041558,2.3839446526313073,-0.2938997945656019,0.36038744680166185,0.001484545851543285,1.1182193515975896,2.2962144810512832,-0.3543509374216771,-0.43569894708233464,0.020785433429236007,-0.017863872838918923,1.0505891507074792,-0.07619722251063903,0.9481038780076505,1.5290369140825837,0.5790392392161661,-0.11532915716857117,0.19240090545282404,0.999504346348033
| 3,425
|
Ion transmembrane transport
| 57
| 169
| 3.673893
| 0.000239
|
P03915,Q9UHG3,P21796,Q70HW3,O95202,Q7KZN9,P45880,O43772,O75844,O60831,Q9H2D1,Q9NRA0,Q96PU5,Q6P4A7,Q8IYU8,P24539,P46934,P05067,Q9UDW1,Q9BQT8,Q13423,P35670,P36383,O75964,Q8NEW0,Q8N4V1,P30825,Q9UJS0,Q9C0H2,Q8N1S5,P08183,Q06787,P51790,Q15043,P53985,P41440,O00400,Q9Y619,Q9Y277,Q6NXT4,Q6PML9,Q15041,P12235,P20674,Q9NQ11,P07384,Q96ES6,Q8TB61,Q9UBX3,P20020,Q96AQ8,Q9HD47,Q14728,Q9HD20,P11413,P00846,Q9Y6M7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
507,4,5,133,382,529,14,143,154,402,157,290,417,538,426,547,423,297,48,305,560,307,430,56,314,186,571,586,70,327,322,324,204,335,591,458,86,221,220,348,349,601,469,353,101,352,231,109,111,235,240,503,366,244,494,121,390
|
2315,86,1622,931,1528,2514,1237,143,813,814,2239,402,1833,3196,2186,2890,1140,154,2150,1496,56,382,2993,914,121,507,916,1533,297,949,2320,1178,1704,352,2946,322,2151,1211,2923,1753,494,469,664,762,1101,724,1313,3020,2849,235,353,982,2104,3304,5,547,2851,1103,2950,3132,873,571,2326,666,307,430,839,1008,1841,458,14,423,1464,1544,3204,745,204,1674,591,1248,2657,1067,1249,1185,600,2900,1041,937,780,1721,2203,1550,1109,324,3298,1505,560,1551,366,1393,601,335,2395,1015,629,799,348,538,1291,349,2495,133,529,3256,1727,426,327,186,1509,314,109,1117,1975,240,964,231,676,1926,1022,417,2834,1566,3040,1403,305,2965,968,70,1299,2673,157,1820,1201,1883,907,1406,244,1330,503,101,290,3406,834,2794,111,48,1825,4,1339,586,1412,1056,220,809,1169,1621,221,3333,390
|
-0.43569894708233464,2.5425880302168293,-0.13496893733397167,0.24879026863223094,-0.09573868680970035,-0.5179207785497725,0.05924575850806966,1.9973622966526008,0.36038744680166185,0.36038744680166185,-0.39491714390968624,0.9481038780076505,-0.23391832955023042,-1.0309922696079223,-0.3746072665047304,-0.7062381065178011,0.11658683691935393,1.9056938106121482,-0.3543509374216771,-0.07619722251063903,3.0567507737172264,0.999504346348033,-0.79146743676524,0.2674983597767239,2.162978192726338,0.7744260494954054,0.2674983597767239,-0.09573868680970035,1.2186519515565648,0.23003816681518965,-0.43569894708233464,0.09751936170847361,-0.1743976571717926,1.0675480922862204,-0.7487318629297377,1.1350418152893942,-0.3543509374216771,0.0784057608191252,-0.7274549681465066,-0.19418721956236745,0.7919594158846363,0.8269144177911181,0.5249283688242936,0.41560864305026346,0.13560845959237622,0.4522133253996353,0.020785433429236007,-0.8129269700518783,-0.6850808626505676,1.448448785568869,1.0675480922862204,0.2112417984925894,-0.3341478103334249,-1.2102024240548812,4.917492659435559,0.7039155427404739,-0.6850808626505676,0.13560845959237622,-0.7487318629297377,-0.9211596241735596,0.304783521666528,0.6684312487998063,-0.43569894708233464,0.5249283688242936,1.1853076769616102,0.8963828986355812,0.34189565270391015,0.19240090545282404,-0.23391832955023042,0.8443364414586735,4.496083243944842,0.9136591415130947,-0.056704463496115395,-0.09573868680970035,-1.0309922696079223,0.4339317726253653,1.6088736896093438,-0.15465833406450158,0.6327920744221581,0.05924575850806966,-0.5801746865595289,0.15458450029912923,0.05924575850806966,0.09751936170847361,0.6149138846414414,-0.7062381065178011,0.17351522707522676,0.24879026863223094,0.3972437030547652,-0.1743976571717926,-0.3746072665047304,-0.09573868680970035,0.13560845959237622,1.1350418152893942,-1.1875599920679472,-0.07619722251063903,0.6861926522306766,-0.09573868680970035,1.0335956619699211,-0.017863872838918923,0.6149138846414414,1.1182193515975896,-0.4561715837491249,0.19240090545282404,0.5790392392161661,0.37883671691997084,1.0844726591413512,0.7216001253197305,0.04003907639528579,1.0844726591413512,-0.4972821326535668,2.10311335779798,0.7392466032253644,-1.0976844720755563,-0.1743976571717926,0.9136591415130947,1.1350418152893942,1.7194151890935954,-0.07619722251063903,1.1685858128764244,2.3108961338926965,0.13560845959237622,-0.27385423081555665,1.4322394553880162,0.23003816681518965,1.4807753146449134,0.5249283688242936,-0.25386051882213734,0.19240090545282404,0.9308994066578831,-0.663982825714329,-0.09573868680970035,-0.8129269700518783,-0.017863872838918923,1.2019963358891592,-0.7487318629297377,0.23003816681518965,2.8655806296701516,0.04003907639528579,-0.5801746865595289,1.9056938106121482,-0.21402733728023318,0.09751936170847361,-0.23391832955023042,0.2861626937330696,-0.017863872838918923,1.4159992226041558,0.020785433429236007,0.7919594158846363,2.3839446526313073,1.2518646944415734,-2.285109634377232,0.36038744680166185,-0.6429435893726733,2.2962144810512832,3.1642440468955613,-0.21402733728023318,5.094411977540183,0.020785433429236007,0.6506311257033517,-0.017863872838918923,0.17351522707522676,1.5290369140825837,0.37883671691997084,0.11658683691935393,-0.11532915716857117,1.5290369140825837,-1.3014824482535676,0.999504346348033
| 3,425
|
Membrane lipid metabolic process
| 23
| 44
| 3.653963
| 0.000258
|
P16278,P06280,P50897,Q13510,Q06136,Q9Y5P4,Q9NRA0,Q9NZJ7,P17900,O15269,Q9Y2B2,Q9P035,P04066,P07602,P04062,Q9NZ01,Q96G23,O43292,O95470,Q8NCC3,Q8NBX0,P06865,P27544
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
10,139,16,17,527,544,290,552,166,172,456,585,576,77,80,94,103,480,118,120,122,384,125
|
172,1095,480,777,1061,118,80,576,139,384,77,1750,10,166,2284,125,651,16,1912,527,1250,17,2662,1597,697,122,120,1048,1924,103,829,903,606,2588,290,806,1822,94,736,552,585,2369,456,544
|
1.7975170034836079,0.13560845959237622,0.8094554736885617,0.3972437030547652,0.15458450029912923,2.2224410858737813,2.62795906725318,0.6506311257033517,2.057946899190213,0.999504346348033,2.7125341584739417,-0.19418721956236745,4.600231735570217,1.8285620188685285,-0.4152809195710186,2.133096436106864,0.5430054701796704,4.33187072621963,-0.25386051882213734,0.7392466032253644,0.05924575850806966,4.3200361894985715,-0.5801746865595289,-0.11532915716857117,0.4886526246803302,2.162978192726338,2.192759466655405,0.17351522707522676,-0.25386051882213734,2.3693825937809168,0.36038744680166185,0.2861626937330696,0.6149138846414414,-0.5386155010309926,1.2518646944415734,0.37883671691997084,-0.21402733728023318,2.4564023437522535,0.4522133253996353,0.7039155427404739,0.6506311257033517,-0.43569894708233464,0.8617217363584101,0.7216001253197305
| 3,425
|
Sphingolipid metabolic process
| 12
| 34
| 3.637757
| 0.000275
|
Q96G23,P17900,P16278,P06280,P07602,P50897,Q13510,P04062,O95470,Q8NCC3,P27544,Q9NZ01
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
103,166,10,139,77,16,17,80,118,120,125,94
|
172,1095,777,118,80,139,384,77,1750,10,166,2284,125,651,16,1912,527,1250,17,2662,1597,697,120,103,606,290,806,1822,94,736,552,585,2369,544
|
1.7975170034836079,0.13560845959237622,0.3972437030547652,2.2224410858737813,2.62795906725318,2.057946899190213,0.999504346348033,2.7125341584739417,-0.19418721956236745,4.600231735570217,1.8285620188685285,-0.4152809195710186,2.133096436106864,0.5430054701796704,4.33187072621963,-0.25386051882213734,0.7392466032253644,0.05924575850806966,4.3200361894985715,-0.5801746865595289,-0.11532915716857117,0.4886526246803302,2.192759466655405,2.3693825937809168,0.6149138846414414,1.2518646944415734,0.37883671691997084,-0.21402733728023318,2.4564023437522535,0.4522133253996353,0.7039155427404739,0.6506311257033517,-0.43569894708233464,0.7216001253197305
| 3,425
|
Endoplasmic reticulum golgi intermediate compartment membrane
| 16
| 32
| 3.617022
| 0.000298
|
Q96RQ1,O15260,P49257,Q10472,P24390,Q12907,Q03519,Q15904,P49755,Q8N511,Q5BJH7,Q9Y282,P56962,Q9Y3B3,Q15363,Q9Y3A6
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
129,99,323,270,12,334,236,177,343,53,247,24,249,284,93,253
|
776,99,506,2417,413,12,3174,323,343,1247,876,249,1636,1640,236,2340,270,334,1284,93,177,247,53,1079,676,129,2460,1001,1777,24,253,284
|
0.3972437030547652,2.3839446526313073,0.7744260494954054,-0.4766991906424338,0.9308994066578831,4.5656364088713355,-0.9868634800659423,1.1350418152893942,1.10136302234031,0.05924575850806966,0.304783521666528,1.3834254662027163,-0.13496893733397167,-0.13496893733397167,1.448448785568869,-0.43569894708233464,1.3014399603266282,1.1182193515975896,0.04003907639528579,2.4564023437522535,1.7819528049746483,1.3997279417347968,3.1106528049037374,0.15458450029912923,0.5249283688242936,2.118117615036976,-0.4766991906424338,0.2112417984925894,-0.19418721956236745,3.709233648956977,1.3670916483246272,1.268422139234549
| 3,425
|
Cognitive impairment
| 54
| 180
| 3.589653
| 0.000331
|
P03915,P16278,P06280,Q14108,Q99720,P50897,Q13510,P49327,Q9BQE5,Q9UBB4,Q9Y263,P21964,P10644,Q9NZJ7,P17900,P40855,Q5XKP0,P05067,O75306,P35670,O95831,O75569,Q9Y2R0,Q9H6K4,Q6DKK2,O43681,P57740,O75503,Q9NQZ5,P07196,P03886,P54802,Q06787,P07602,Q9NPL8,P04062,Q03164,Q8N0X7,Q96F07,Q9Y619,P49770,Q6PML9,P12235,Q9UI10,O15118,Q9NQ11,O60313,Q9NZ08,O95470,P35637,Q9NP73,P00846,P06865,P27544
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
507,10,139,13,15,16,17,526,20,543,418,414,163,552,166,422,561,297,173,307,557,555,54,57,185,311,436,62,320,447,69,202,324,77,465,80,211,461,474,221,346,349,469,493,97,101,482,113,118,495,376,121,384,125
|
1306,2970,97,777,311,709,482,1493,1946,173,1577,62,555,691,913,1382,2375,118,557,1457,1900,914,121,2804,69,507,80,1582,915,2805,297,139,384,447,77,1750,3129,2152,3405,1583,3052,163,1274,469,795,1101,3377,10,3200,166,951,1275,1797,3304,952,414,3184,816,2894,125,2518,2060,693,1214,495,307,1008,1841,422,1181,2108,1542,1386,3203,526,1713,346,16,2566,2736,2198,1673,202,1545,3059,2067,920,436,1589,2900,1218,1547,2699,1964,211,2527,2738,3119,324,1806,727,3028,695,2489,2820,1761,614,17,13,1111,2207,2208,2345,1767,2164,2870,1472,1397,561,185,3341,1325,993,2078,349,3223,3314,1475,461,1648,617,717,2498,2300,2787,1327,474,3328,1263,1000,943,2671,1688,2834,2875,2632,15,20,1774,57,3391,376,1407,465,101,2791,320,1126,3302,3384,2638,806,113,552,543,1450,2177,493,586,1826,2724,1828,1168,418,54,634,1621,835,221,2414
|
0.020785433429236007,-0.7700692108929594,2.3984830795821077,0.3972437030547652,1.1685858128764244,0.4704535329188798,0.8094554736885617,-0.07619722251063903,-0.27385423081555665,1.7975170034836079,-0.11532915716857117,2.947996335155421,0.6861926522306766,0.4886526246803302,0.2674983597767239,-0.017863872838918923,-0.4561715837491249,2.2224410858737813,0.6861926522306766,-0.056704463496115395,-0.25386051882213734,0.2674983597767239,2.162978192726338,-0.663982825714329,2.8655806296701516,0.7744260494954054,2.62795906725318,-0.11532915716857117,0.2674983597767239,-0.663982825714329,1.2186519515565648,2.057946899190213,0.999504346348033,0.8617217363584101,2.7125341584739417,-0.19418721956236745,-0.9211596241735596,-0.3543509374216771,-2.285109634377232,-0.11532915716857117,-0.8344482451084184,1.844043079409893,0.04003907639528579,0.8269144177911181,0.37883671691997084,0.13560845959237622,-1.6303721469296955,4.600231735570217,-1.0309922696079223,1.8285620188685285,0.23003816681518965,0.04003907639528579,-0.21402733728023318,-1.2102024240548812,0.23003816681518965,0.9308994066578831,-1.00889493373649,0.36038744680166185,-0.7062381065178011,2.133096436106864,-0.5179207785497725,-0.31399754246940065,0.4886526246803302,0.0784057608191252,0.7919594158846363,1.1853076769616102,0.19240090545282404,-0.23391832955023042,0.9136591415130947,0.09751936170847361,-0.3341478103334249,-0.09573868680970035,-0.017863872838918923,-1.0309922696079223,0.7392466032253644,-0.1743976571717926,1.0844726591413512,4.33187072621963,-0.5386155010309926,-0.6219627517160322,-0.3746072665047304,-0.15465833406450158,1.6247523908291193,-0.09573868680970035,-0.8344482451084184,-0.31399754246940065,0.2674983597767239,0.8790704925764257,-0.11532915716857117,-0.7062381065178011,0.0784057608191252,-0.09573868680970035,-0.6010399151957811,-0.27385423081555665,1.5450638238651857,-0.5179207785497725,-0.6219627517160322,-0.8993869388026995,1.1350418152893942,-0.21402733728023318,0.4522133253996353,-0.8129269700518783,0.4886526246803302,-0.4972821326535668,-0.663982825714329,-0.19418721956236745,0.5969963442295187,4.3200361894985715,4.530920591223999,0.13560845959237622,-0.3746072665047304,-0.3746072665047304,-0.43569894708233464,-0.19418721956236745,-0.3543509374216771,-0.6850808626505676,-0.056704463496115395,-0.017863872838918923,0.6861926522306766,1.7194151890935954,-1.3475564028664557,0.020785433429236007,0.2112417984925894,-0.31399754246940065,1.0844726591413512,-1.0531559749508097,-1.2329153395499515,-0.056704463496115395,0.8443364414586735,-0.13496893733397167,0.5969963442295187,0.4704535329188798,-0.4972821326535668,-0.4152809195710186,-0.6429435893726733,0.020785433429236007,0.8269144177911181,-1.2785547987944277,0.05924575850806966,0.2112417984925894,0.24879026863223094,-0.5801746865595289,-0.15465833406450158,-0.663982825714329,-0.6850808626505676,-0.5593666767876478,4.355497276975648,4.007216364080601,-0.19418721956236745,3.0432261828019507,-1.825360370605193,1.0165674522554908,-0.017863872838918923,0.8443364414586735,2.3839446526313073,-0.6429435893726733,1.1518305804680873,0.13560845959237622,-1.1875599920679472,-1.7271928388381075,-0.5593666767876478,0.37883671691997084,2.281508618182512,0.7039155427404739,0.7216001253197305,-0.03726011192253851,-0.3543509374216771,0.8094554736885617,0.6506311257033517,-0.21402733728023318,-0.6010399151957811,-0.21402733728023318,0.11658683691935393,0.9308994066578831,3.097206606706352,0.5790392392161661,-0.11532915716857117,0.36038744680166185,1.5290369140825837,-0.4561715837491249
| 3,425
|
SLC superfamily of solute carriers
| 29
| 52
| 3.47713
| 0.000507
|
O95202,Q70HW3,O43772,Q9H2D1,Q9BSK2,P12236,Q9NZJ7,Q6NT16,Q96H78,Q9BQT8,Q5T1Q4,Q8NEW0,P30825,Q9UJS0,Q8N1S5,Q15043,P53985,P41440,Q6NUK1,O00400,Q9Y619,Q6NXT4,Q6PML9,P12235,Q8IXU6,Q8TB61,Q9UBX3,Q9Y6C9,Q9Y6M7
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
382,133,143,157,288,664,552,300,47,305,183,314,571,586,327,335,591,458,604,86,221,348,349,469,233,109,111,635,390
|
86,1746,143,813,1140,382,949,2151,1274,469,664,571,458,1674,591,1067,1721,1550,335,1015,183,3394,300,604,348,1814,349,133,233,327,314,109,684,47,1022,1735,1230,305,288,968,1299,157,1201,1883,907,1406,552,111,586,221,635,390
|
2.5425880302168293,-0.19418721956236745,1.9973622966526008,0.36038744680166185,0.11658683691935393,0.999504346348033,0.23003816681518965,-0.3543509374216771,0.04003907639528579,0.8269144177911181,0.5249283688242936,0.6684312487998063,0.8443364414586735,-0.15465833406450158,0.6327920744221581,0.15458450029912923,-0.1743976571717926,-0.09573868680970035,1.1182193515975896,0.19240090545282404,1.7507404107076854,-1.8749638166066318,1.2186519515565648,0.6149138846414414,1.0844726591413512,-0.21402733728023318,1.0844726591413512,2.10311335779798,1.4646273575456767,1.1350418152893942,1.1685858128764244,2.3108961338926965,0.5068108281574367,3.1642440468955613,0.19240090545282404,-0.1743976571717926,0.0784057608191252,1.2019963358891592,1.2518646944415734,0.23003816681518965,0.04003907639528579,1.9056938106121482,0.09751936170847361,-0.23391832955023042,0.2861626937330696,-0.017863872838918923,0.7039155427404739,2.2962144810512832,0.6506311257033517,1.5290369140825837,0.5790392392161661,0.999504346348033
| 3,425
|
secondary carrier transporter
| 10
| 19
| 3.471844
| 0.000517
|
Q8N1S5,Q96ES6,Q6NT16,Q8TB61,Q15043,Q96H78,Q9BQT8,Q9UBX3,O00400,Q9Y6M7
|
Functions
|
Panther Protein class
|
panther_protein_class
|
327,231,300,109,335,47,305,111,86,390
|
86,1746,1140,382,1067,1550,335,300,1814,327,109,231,47,305,968,1201,111,586,390
|
2.5425880302168293,-0.19418721956236745,0.11658683691935393,0.999504346348033,0.15458450029912923,-0.09573868680970035,1.1182193515975896,1.2186519515565648,-0.21402733728023318,1.1350418152893942,2.3108961338926965,1.4807753146449134,3.1642440468955613,1.2019963358891592,0.23003816681518965,0.09751936170847361,2.2962144810512832,0.6506311257033517,0.999504346348033
| 3,425
|
Sphingolipid metabolism
| 18
| 30
| 3.46893
| 0.000523
|
Q96G23,Q8NBJ7,P17900,P16278,P06280,O15269,P51648,P07602,P04062,Q13510,Q06136,P10619,P06865,O95470,Q9Y5P4,P27544,O43681,Q9NRA0
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
103,394,166,10,139,172,141,77,80,17,527,114,384,118,544,125,311,290
|
1489,172,1095,311,2845,118,80,139,384,77,1750,114,3377,10,166,2284,125,141,527,17,1597,394,103,1931,290,1822,736,552,2369,544
|
-0.07619722251063903,1.7975170034836079,0.13560845959237622,1.1685858128764244,-0.6850808626505676,2.2224410858737813,2.62795906725318,2.057946899190213,0.999504346348033,2.7125341584739417,-0.19418721956236745,2.2667784467407786,-1.6303721469296955,4.600231735570217,1.8285620188685285,-0.4152809195710186,2.133096436106864,2.027706771884764,0.7392466032253644,4.3200361894985715,-0.11532915716857117,0.9824061676177961,2.3693825937809168,-0.25386051882213734,1.2518646944415734,-0.21402733728023318,0.4522133253996353,0.7039155427404739,-0.43569894708233464,0.7216001253197305
| 3,425
|
Golgi apparatus
| 74
| 201
| 3.447565
| 0.000566
|
Q96RQ1,O15321,O43752,P80303,Q8IZA0,P50851,O15212,P16278,A1L0T0,P24390,O15127,P67812,P50897,O75071,A4D1U4,Q9Y5P4,Q969E2,Q9HB40,O60658,O95070,Q5VW38,Q6NT16,Q99523,Q8N4Q0,Q9BSR8,Q12893,P11717,P10586,P05067,O60476,Q9UEU0,Q02818,P35670,Q96SU4,O95295,Q8TBA6,Q8NEW0,P20340,O00461,Q9NWM8,Q8N4A0,Q92896,O60637,Q8NC54,O00231,O14681,Q9H4A6,Q96ND0,Q15043,Q9NW68,P49755,O95302,Q9UKV5,Q9UBU6,Q93050,Q6NXT4,O60499,O15260,Q6ZU35,P09601,Q6NUQ1,Q5KU26,Q8IXU6,Q9HD45,O43760,Q9BRK5,Q92520,Q9NXS2,Q9BV57,Q6ZRP7,Q5BJH7,Q8NCH0,Q96J42,Q8IYS2
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
129,378,379,6,259,639,515,10,505,12,142,269,16,144,148,544,539,30,160,413,38,300,686,171,301,683,682,681,297,302,706,51,307,703,556,701,314,570,66,194,328,198,71,200,575,332,596,207,335,466,343,85,610,219,473,348,225,99,100,102,354,486,233,362,481,370,369,241,502,631,247,123,126,643
|
505,1991,148,3381,2886,575,66,946,332,1942,739,142,515,1346,99,378,1993,2514,2277,812,2972,379,481,302,1995,225,71,160,1238,1493,144,3145,2149,853,895,413,556,85,1209,3294,1311,297,3355,102,681,3163,682,3377,10,3356,570,2284,12,1427,1839,2155,2286,1351,307,1315,856,2733,1588,1279,1905,343,745,639,16,2566,1673,746,1066,2519,2898,1039,2697,3117,269,6,2737,780,1964,51,1912,3313,2340,989,1434,683,1284,1763,3255,1913,2343,879,335,1016,247,922,486,2579,1682,38,2443,961,1157,300,882,354,2622,348,1078,1815,939,631,3314,100,2259,2449,2785,3137,1326,3167,233,643,259,2031,328,171,699,1864,200,123,314,701,3363,942,369,1867,198,1975,473,783,539,3332,734,2833,126,207,2752,129,703,686,926,2547,927,3040,3300,370,904,301,502,1933,832,1777,1480,1124,3042,596,2674,3391,3364,30,907,1330,362,1981,2463,1127,1026,466,194,971,241,908,2310,1886,219,706,791,1130,1087,807,3211,610,2145,1302,3046,544,1452
|
0.7744260494954054,-0.2938997945656019,1.9669125823347013,-1.702863183258117,-0.7062381065178011,0.6506311257033517,2.879367974649712,0.23003816681518965,1.1182193515975896,-0.27385423081555665,0.4339317726253653,1.9973622966526008,0.7568551780007351,0.001484545851543285,2.3839446526313073,0.999504346348033,-0.2938997945656019,-0.5179207785497725,-0.4152809195710186,0.36038744680166185,-0.7700692108929594,0.999504346348033,0.8094554736885617,1.2019963358891592,-0.2938997945656019,1.4968927991314636,2.8517725495914763,1.8594966695461037,0.05924575850806966,-0.07619722251063903,1.9973622966526008,-0.9429962985415629,-0.3543509374216771,0.32336109245226435,0.2861626937330696,0.9308994066578831,0.6861926522306766,2.5568725955541236,0.0784057608191252,-1.1875599920679472,0.020785433429236007,1.2186519515565648,-1.44059515439419,2.3693825937809168,0.5068108281574367,-0.9648974270030561,0.5068108281574367,-1.6303721469296955,4.600231735570217,-1.44059515439419,0.6684312487998063,-0.4152809195710186,4.5656364088713355,-0.03726011192253851,-0.23391832955023042,-0.3543509374216771,-0.4152809195710186,0.001484545851543285,1.1853076769616102,0.020785433429236007,0.32336109245226435,-0.6219627517160322,-0.11532915716857117,0.04003907639528579,-0.25386051882213734,1.10136302234031,0.4339317726253653,0.5610423537706956,4.33187072621963,-0.5386155010309926,-0.15465833406450158,0.4339317726253653,0.15458450029912923,-0.5179207785497725,-0.7062381065178011,0.17351522707522676,-0.6010399151957811,-0.8993869388026995,1.3014399603266282,4.895159421570552,-0.6219627517160322,0.3972437030547652,-0.27385423081555665,3.137486998744578,-0.25386051882213734,-1.2329153395499515,-0.43569894708233464,0.2112417984925894,-0.03726011192253851,0.5068108281574367,0.04003907639528579,-0.19418721956236745,-1.0976844720755563,-0.25386051882213734,-0.43569894708233464,0.304783521666528,1.1182193515975896,0.19240090545282404,1.3997279417347968,0.2674983597767239,0.8094554736885617,-0.5386155010309926,-0.15465833406450158,3.362516803273496,-0.4766991906424338,0.23003816681518965,0.11658683691935393,1.2186519515565648,0.304783521666528,1.0675480922862204,-0.5593666767876478,1.0844726591413512,0.15458450029912923,-0.21402733728023318,0.24879026863223094,0.5790392392161661,-1.2329153395499515,2.3839446526313073,-0.39491714390968624,-0.4766991906424338,-0.6429435893726733,-0.9211596241735596,0.020785433429236007,-0.9648974270030561,1.4646273575456767,0.5610423537706956,1.3343293891978911,-0.2938997945656019,1.1350418152893942,1.813053367361717,0.4886526246803302,-0.23391832955023042,1.6406018537801237,2.162978192726338,1.1685858128764244,0.4886526246803302,-1.5111725380859105,0.24879026863223094,1.0335956619699211,-0.23391832955023042,1.6722135928008373,-0.27385423081555665,0.8269144177911181,0.3972437030547652,0.7216001253197305,-1.3014824482535676,0.4522133253996353,-0.663982825714329,2.133096436106864,1.592965616941986,-0.6219627517160322,2.118117615036976,0.4886526246803302,0.5068108281574367,0.2674983597767239,-0.5179207785497725,0.2674983597767239,-0.8129269700518783,-1.1875599920679472,1.0335956619699211,0.2861626937330696,1.2186519515565648,0.7919594158846363,-0.25386051882213734,0.36038744680166185,-0.19418721956236745,-0.056704463496115395,0.13560845959237622,-0.8129269700518783,0.6327920744221581,-0.5801746865595289,-1.825360370605193,-1.5111725380859105,3.5053048346626823,0.2861626937330696,0.020785433429236007,1.0505891507074792,-0.27385423081555665,-0.4766991906424338,0.13560845959237622,0.19240090545282404,0.8443364414586735,1.6879761304662688,0.23003816681518965,1.4322394553880162,0.2861626937330696,-0.4152809195710186,-0.23391832955023042,1.5290369140825837,0.4886526246803302,0.3972437030547652,0.13560845959237622,0.15458450029912923,0.37883671691997084,-1.0309922696079223,0.6149138846414414,-0.3341478103334249,0.04003907639528579,-0.8129269700518783,0.7216001253197305,-0.03726011192253851
| 3,425
|
Anion transmembrane transport
| 21
| 43
| 3.432498
| 0.000598
|
Q9UHG3,P21796,P45880,O60831,Q9H2D1,P33527,Q9BQT8,P30825,Q9UJS0,P08183,P51790,P53985,P41440,Q9Y619,Q9Y277,Q15041,P12235,Q8TB61,Q9UBX3,Q14728,Q9Y6M7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,5,14,402,157,666,305,571,586,322,204,591,458,221,220,601,469,109,111,366,390
|
2514,813,402,1140,2150,949,2320,322,2151,469,664,5,571,666,458,14,204,1674,591,1067,1721,1550,366,601,1015,799,3256,109,1022,305,968,157,1201,1883,1406,1330,111,4,586,220,1169,221,390
|
-0.5179207785497725,0.36038744680166185,0.9481038780076505,0.11658683691935393,-0.3543509374216771,0.23003816681518965,-0.43569894708233464,1.1350418152893942,-0.3543509374216771,0.8269144177911181,0.5249283688242936,4.917492659435559,0.6684312487998063,0.5249283688242936,0.8443364414586735,4.496083243944842,1.6088736896093438,-0.15465833406450158,0.6327920744221581,0.15458450029912923,-0.1743976571717926,-0.09573868680970035,1.0335956619699211,0.6149138846414414,0.19240090545282404,0.37883671691997084,-1.0976844720755563,2.3108961338926965,0.19240090545282404,1.2019963358891592,0.23003816681518965,1.9056938106121482,0.09751936170847361,-0.23391832955023042,-0.017863872838918923,0.020785433429236007,2.2962144810512832,5.094411977540183,0.6506311257033517,1.5290369140825837,0.11658683691935393,1.5290369140825837,0.999504346348033
| 3,425
|
Ion transport
| 69
| 220
| 3.297115
| 0.000977
|
P03915,Q9UHG3,P21796,Q70HW3,O95202,Q7KZN9,P45880,O43772,Q9Y5P4,O75844,O60831,Q9H2D1,Q9NRA0,Q96PU5,Q6P4A7,Q9NZJ7,Q8IYU8,P24539,P46934,P05067,Q9UDW1,Q9BQT8,Q13423,P35670,P36383,O75964,Q8NEW0,Q8N4V1,P30825,O43681,Q8NE01,Q9UJS0,Q9C0H2,Q8N1S5,P08183,Q06787,P51790,P07602,P14174,Q15043,Q9H0H5,P53985,P41440,Q6NUK1,O00400,Q9Y619,Q9Y277,Q6NXT4,Q6PML9,Q15041,P61421,P12235,P11413,P20674,Q9NQ11,O15173,Q96ES6,P07384,Q8TB61,Q9UBX3,P20020,Q96AQ8,P30536,Q14728,Q9HD20,Q9HD47,Q16611,P00846,Q9Y6M7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
507,4,5,133,382,529,14,143,544,154,402,157,290,417,538,552,426,547,423,297,48,305,560,307,430,56,314,186,571,311,582,586,70,327,322,324,204,77,333,335,464,591,458,604,86,221,220,348,349,601,600,469,494,353,101,229,231,352,109,111,235,240,242,366,244,503,629,121,390
|
3157,2315,86,1306,1622,931,1528,775,229,2514,311,1237,143,813,814,2239,402,1833,3196,2186,2890,1140,154,2150,1496,56,691,382,2686,2993,1457,914,121,710,507,778,916,1533,297,949,2320,1178,1704,352,77,2946,322,2151,1211,2923,1753,1274,2947,494,469,664,762,1836,333,1101,724,1313,3020,2849,235,353,982,2104,3304,5,547,2193,2851,1103,2950,871,3132,242,873,571,693,2326,2652,1384,666,1755,307,430,839,1008,1841,458,14,1588,423,1464,1544,3204,745,204,819,1674,591,2199,1248,2657,1067,1249,1185,1356,600,2900,1041,937,780,1721,2203,2699,1591,1550,1109,324,2254,1806,628,3298,1505,1250,560,3102,1551,366,1393,601,335,2395,3190,1015,1679,629,2535,799,3394,604,348,1814,538,1291,349,2495,133,529,3256,1727,426,327,186,582,1509,314,109,1117,1975,240,964,231,676,1926,1022,417,1735,803,2834,1566,1230,3040,1403,305,2965,968,70,464,1299,2673,157,1820,1201,1883,907,1406,244,1330,503,101,290,3406,834,736,552,2794,111,48,1825,4,2370,1339,586,1412,2049,1056,2758,1376,220,809,1169,1621,544,221,3333,390
|
-0.9648974270030561,-0.43569894708233464,2.5425880302168293,0.020785433429236007,-0.13496893733397167,0.24879026863223094,-0.09573868680970035,0.3972437030547652,1.4807753146449134,-0.5179207785497725,1.1685858128764244,0.05924575850806966,1.9973622966526008,0.36038744680166185,0.36038744680166185,-0.39491714390968624,0.9481038780076505,-0.23391832955023042,-1.0309922696079223,-0.3746072665047304,-0.7062381065178011,0.11658683691935393,1.9056938106121482,-0.3543509374216771,-0.07619722251063903,3.0567507737172264,0.4886526246803302,0.999504346348033,-0.6010399151957811,-0.79146743676524,-0.056704463496115395,0.2674983597767239,2.162978192726338,0.4704535329188798,0.7744260494954054,0.3972437030547652,0.2674983597767239,-0.09573868680970035,1.2186519515565648,0.23003816681518965,-0.43569894708233464,0.09751936170847361,-0.1743976571717926,1.0675480922862204,2.7125341584739417,-0.7487318629297377,1.1350418152893942,-0.3543509374216771,0.0784057608191252,-0.7274549681465066,-0.19418721956236745,0.04003907639528579,-0.7487318629297377,0.7919594158846363,0.8269144177911181,0.5249283688242936,0.41560864305026346,-0.23391832955023042,1.1182193515975896,0.13560845959237622,0.4522133253996353,0.020785433429236007,-0.8129269700518783,-0.6850808626505676,1.448448785568869,1.0675480922862204,0.2112417984925894,-0.3341478103334249,-1.2102024240548812,4.917492659435559,0.7039155427404739,-0.3746072665047304,-0.6850808626505676,0.13560845959237622,-0.7487318629297377,0.304783521666528,-0.9211596241735596,1.4159992226041558,0.304783521666528,0.6684312487998063,0.4886526246803302,-0.43569894708233464,-0.5801746865595289,-0.017863872838918923,0.5249283688242936,-0.19418721956236745,1.1853076769616102,0.8963828986355812,0.34189565270391015,0.19240090545282404,-0.23391832955023042,0.8443364414586735,4.496083243944842,-0.11532915716857117,0.9136591415130947,-0.056704463496115395,-0.09573868680970035,-1.0309922696079223,0.4339317726253653,1.6088736896093438,0.36038744680166185,-0.15465833406450158,0.6327920744221581,-0.3746072665047304,0.05924575850806966,-0.5801746865595289,0.15458450029912923,0.05924575850806966,0.09751936170847361,0.001484545851543285,0.6149138846414414,-0.7062381065178011,0.17351522707522676,0.24879026863223094,0.3972437030547652,-0.1743976571717926,-0.3746072665047304,-0.6010399151957811,-0.11532915716857117,-0.09573868680970035,0.13560845959237622,1.1350418152893942,-0.39491714390968624,-0.21402733728023318,0.5790392392161661,-1.1875599920679472,-0.07619722251063903,0.05924575850806966,0.6861926522306766,-0.8776777826591424,-0.09573868680970035,1.0335956619699211,-0.017863872838918923,0.6149138846414414,1.1182193515975896,-0.4561715837491249,-1.00889493373649,0.19240090545282404,-0.15465833406450158,0.5790392392161661,-0.5179207785497725,0.37883671691997084,-1.8749638166066318,0.6149138846414414,1.0844726591413512,-0.21402733728023318,0.7216001253197305,0.04003907639528579,1.0844726591413512,-0.4972821326535668,2.10311335779798,0.7392466032253644,-1.0976844720755563,-0.1743976571717926,0.9136591415130947,1.1350418152893942,1.7194151890935954,0.6506311257033517,-0.07619722251063903,1.1685858128764244,2.3108961338926965,0.13560845959237622,-0.27385423081555665,1.4322394553880162,0.23003816681518965,1.4807753146449134,0.5249283688242936,-0.25386051882213734,0.19240090545282404,0.9308994066578831,-0.1743976571717926,0.37883671691997084,-0.663982825714329,-0.09573868680970035,0.0784057608191252,-0.8129269700518783,-0.017863872838918923,1.2019963358891592,-0.7487318629297377,0.23003816681518965,2.8655806296701516,0.8443364414586735,0.04003907639528579,-0.5801746865595289,1.9056938106121482,-0.21402733728023318,0.09751936170847361,-0.23391832955023042,0.2861626937330696,-0.017863872838918923,1.4159992226041558,0.020785433429236007,0.7919594158846363,2.3839446526313073,1.2518646944415734,-2.285109634377232,0.36038744680166185,0.4522133253996353,0.7039155427404739,-0.6429435893726733,2.2962144810512832,3.1642440468955613,-0.21402733728023318,5.094411977540183,-0.43569894708233464,0.020785433429236007,0.6506311257033517,-0.017863872838918923,-0.2938997945656019,0.17351522707522676,-0.6219627517160322,0.001484545851543285,1.5290369140825837,0.37883671691997084,0.11658683691935393,-0.11532915716857117,0.7216001253197305,1.5290369140825837,-1.3014824482535676,0.999504346348033
| 3,425
|
SLC25 family of mitochondrial transporters
| 14
| 23
| 3.244146
| 0.001178
|
Q9UJS0,P12236,Q70HW3,Q9NZJ7,O43772,Q96H78,Q9BQT8,Q9UBX3,Q9Y6C9,Q9H2D1,Q6NUK1,Q9Y619,Q9BSK2,P12235
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
586,664,133,552,143,47,305,111,635,157,604,221,288,469
|
143,813,1140,949,469,664,1674,1721,1550,604,133,684,47,305,288,157,1201,1406,552,111,586,221,635
|
1.9973622966526008,0.36038744680166185,0.11658683691935393,0.23003816681518965,0.8269144177911181,0.5249283688242936,-0.15465833406450158,-0.1743976571717926,-0.09573868680970035,0.6149138846414414,2.10311335779798,0.5068108281574367,3.1642440468955613,1.2019963358891592,1.2518646944415734,1.9056938106121482,0.09751936170847361,-0.017863872838918923,0.7039155427404739,2.2962144810512832,0.6506311257033517,1.5290369140825837,0.5790392392161661
| 3,425
|
Mitochondrial carrier domain superfamily [IPR023395]
| 14
| 23
| 3.244146
| 0.001178
|
Q9UJS0,P12236,Q70HW3,Q9NZJ7,O43772,Q96H78,Q9BQT8,Q9UBX3,Q9Y6C9,Q9H2D1,Q6NUK1,Q9Y619,Q9BSK2,P12235
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
586,664,133,552,143,47,305,111,635,157,604,221,288,469
|
143,813,1140,949,469,664,1674,1721,1550,604,133,684,47,305,288,157,1201,1406,552,111,586,221,635
|
1.9973622966526008,0.36038744680166185,0.11658683691935393,0.23003816681518965,0.8269144177911181,0.5249283688242936,-0.15465833406450158,-0.1743976571717926,-0.09573868680970035,0.6149138846414414,2.10311335779798,0.5068108281574367,3.1642440468955613,1.2019963358891592,1.2518646944415734,1.9056938106121482,0.09751936170847361,-0.017863872838918923,0.7039155427404739,2.2962144810512832,0.6506311257033517,1.5290369140825837,0.5790392392161661
| 3,425
|
Mitochondrial substrate/solute carrier [IPR018108]
| 14
| 23
| 3.244146
| 0.001178
|
Q9UJS0,P12236,Q70HW3,Q9NZJ7,O43772,Q96H78,Q9BQT8,Q9UBX3,Q9Y6C9,Q9H2D1,Q6NUK1,Q9Y619,Q9BSK2,P12235
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
586,664,133,552,143,47,305,111,635,157,604,221,288,469
|
143,813,1140,949,469,664,1674,1721,1550,604,133,684,47,305,288,157,1201,1406,552,111,586,221,635
|
1.9973622966526008,0.36038744680166185,0.11658683691935393,0.23003816681518965,0.8269144177911181,0.5249283688242936,-0.15465833406450158,-0.1743976571717926,-0.09573868680970035,0.6149138846414414,2.10311335779798,0.5068108281574367,3.1642440468955613,1.2019963358891592,1.2518646944415734,1.9056938106121482,0.09751936170847361,-0.017863872838918923,0.7039155427404739,2.2962144810512832,0.6506311257033517,1.5290369140825837,0.5790392392161661
| 3,425
|
Protein transporter activity
| 9
| 16
| 3.236898
| 0.001208
|
Q99595,O60830,Q9Y584,Q9NS69,Q9Y5J9,P49755,Q9HD20,O14925,Q9UGP8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
1,2,44,18,411,343,244,340,389
|
340,2,1380,1457,343,2900,798,416,1361,1,244,18,389,44,1170,411
|
1.10136302234031,5.203448495367863,-0.017863872838918923,-0.056704463496115395,1.10136302234031,-0.7062381065178011,0.37883671691997084,0.9308994066578831,0.001484545851543285,5.246740467606561,1.4159992226041558,4.212879893636516,0.999504346348033,3.2440577254623797,0.11658683691935393,0.9481038780076505
| 3,425
|
Golgi membrane
| 63
| 153
| 3.234965
| 0.001217
|
O15498,P35613,O43752,Q8IZA0,Q9Y296,Q9BXS4,P24390,Q14108,Q10472,P10321,O15155,Q15436,P98194,Q9Y282,Q9P2W9,Q93063,P30511,Q9Y3B3,Q9Y5Z9,O95070,Q15392,O95721,Q12893,P11717,O60476,O95249,P35670,Q9P2E5,O95295,Q8TBA6,Q8NF37,Q8N6H7,Q8N4V1,P20340,O00461,Q8N4A0,Q92896,P49257,P51790,Q9H4A6,Q12907,Q8IV08,P49755,O00400,Q9H7Z7,O95197,Q10713,Q6NXT4,Q15363,Q7LGA3,O60499,O15260,Q9BUR5,O43505,P50570,Q8TB61,L0R6Q1,O15027,Q9NXS2,Q6ZRP7,P48739,Q5BJH7,Q8NCH0
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
506,254,379,259,793,138,12,13,270,396,776,781,780,24,153,783,28,284,810,413,36,663,683,682,302,303,307,442,556,701,700,699,186,570,66,328,198,323,204,596,334,79,343,86,478,90,727,348,93,350,225,99,621,104,745,109,738,739,241,631,743,247,123
|
738,86,66,946,2600,739,776,1346,99,506,104,2645,379,302,225,1238,2417,413,90,303,556,663,2804,1311,1212,2923,396,1274,682,570,2284,12,28,1351,254,307,2429,856,1181,1905,743,323,343,745,1634,1247,204,1010,1066,2519,2898,3218,1011,2020,2569,1636,1069,1804,2157,3117,2250,1108,2737,780,3313,2340,989,270,1434,727,683,334,1284,1850,13,2343,3122,2395,93,36,781,1016,2077,247,882,348,939,631,350,2665,1326,1021,79,259,328,186,699,1864,123,700,109,701,1866,1867,2358,198,783,1079,2669,1162,803,927,621,2460,1445,138,3112,832,1777,1568,1124,596,478,2674,1371,3391,907,1330,2463,1333,1026,1822,241,2369,442,153,2232,1886,1825,1937,1268,1056,24,793,1269,3046,2472,1657,284,1525,1661,810,1452
|
0.4339317726253653,2.5425880302168293,2.879367974649712,0.23003816681518965,-0.5593666767876478,0.4339317726253653,0.3972437030547652,0.001484545851543285,2.3839446526313073,0.7744260494954054,2.340187200505293,-0.5801746865595289,0.999504346348033,1.2019963358891592,1.4968927991314636,0.05924575850806966,-0.4766991906424338,0.9308994066578831,2.5139509284160675,1.2019963358891592,0.6861926522306766,0.5249283688242936,-0.663982825714329,0.020785433429236007,0.0784057608191252,-0.7274549681465066,0.9652727380057537,0.04003907639528579,0.5068108281574367,0.6684312487998063,-0.4152809195710186,4.5656364088713355,3.6205514552672318,0.001484545851543285,1.3507263392996962,1.1853076769616102,-0.4766991906424338,0.32336109245226435,0.09751936170847361,-0.25386051882213734,0.4339317726253653,1.1350418152893942,1.10136302234031,0.4339317726253653,-0.13496893733397167,0.05924575850806966,1.6088736896093438,0.19240090545282404,0.15458450029912923,-0.5179207785497725,-0.7062381065178011,-1.0531559749508097,0.19240090545282404,-0.2938997945656019,-0.5386155010309926,-0.13496893733397167,0.15458450029912923,-0.21402733728023318,-0.3543509374216771,-0.8993869388026995,-0.39491714390968624,0.13560845959237622,-0.6219627517160322,0.3972437030547652,-1.2329153395499515,-0.43569894708233464,0.2112417984925894,1.3014399603266282,-0.03726011192253851,0.4522133253996353,0.5068108281574367,1.1182193515975896,0.04003907639528579,-0.23391832955023042,4.530920591223999,-0.43569894708233464,-0.8993869388026995,-0.4561715837491249,2.4564023437522535,3.3886394720355844,0.3972437030547652,0.19240090545282404,-0.31399754246940065,1.3997279417347968,0.304783521666528,1.0844726591413512,0.24879026863223094,0.5790392392161661,1.0844726591413512,-0.5801746865595289,0.020785433429236007,0.19240090545282404,2.6703449638891956,1.3343293891978911,1.1350418152893942,1.7194151890935954,0.4886526246803302,-0.23391832955023042,2.162978192726338,0.4886526246803302,2.3108961338926965,0.4886526246803302,-0.23391832955023042,-0.23391832955023042,-0.43569894708233464,1.6722135928008373,0.3972437030547652,0.15458450029912923,-0.5801746865595289,0.11658683691935393,0.37883671691997084,0.2674983597767239,0.5969963442295187,-0.4766991906424338,-0.03726011192253851,2.0730281075790966,-0.8776777826591424,0.36038744680166185,-0.19418721956236745,-0.09573868680970035,0.13560845959237622,0.6327920744221581,0.8269144177911181,-0.5801746865595289,0.001484545851543285,-1.825360370605193,0.2861626937330696,0.020785433429236007,-0.4766991906424338,0.020785433429236007,0.19240090545282404,-0.21402733728023318,1.4322394553880162,-0.43569894708233464,0.8790704925764257,1.9210387080998343,-0.3746072665047304,-0.23391832955023042,-0.21402733728023318,-0.25386051882213734,0.05924575850806966,0.17351522707522676,3.709233648956977,0.3972437030547652,0.05924575850806966,-0.8129269700518783,-0.4766991906424338,-0.13496893733397167,1.268422139234549,-0.07619722251063903,-0.13496893733397167,0.37883671691997084,-0.03726011192253851
| 3,425
|
Intrinsic component of mitochondrial inner membrane
| 21
| 36
| 3.231077
| 0.001233
|
Q99595,O60830,Q15070,Q9UG56,Q8N8Q8,Q6P4A7,Q5XKP0,Q16134,Q9NWR8,Q9Y2R0,Q6UXV4,P50336,Q9NX63,Q9H3K2,Q13505,Q9H9P8,O43819,O14925,Q9Y512,Q9BUR5,Q96AQ8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,2,520,791,272,538,561,304,834,54,696,818,195,720,73,597,709,340,761,621,240
|
340,709,2,1172,1175,3249,818,1721,73,520,304,820,2662,1596,561,538,696,272,1509,240,964,1022,1,621,2366,720,1883,597,1406,1653,834,195,791,54,1621,761
|
1.10136302234031,0.4704535329188798,5.203448495367863,0.09751936170847361,0.09751936170847361,-1.0976844720755563,0.36038744680166185,-0.1743976571717926,2.8379436574544386,0.7568551780007351,1.2019963358891592,0.36038744680166185,-0.5801746865595289,-0.11532915716857117,0.6861926522306766,0.7216001253197305,0.4886526246803302,1.3014399603266282,-0.07619722251063903,1.4322394553880162,0.23003816681518965,0.19240090545282404,5.246740467606561,0.5969963442295187,-0.43569894708233464,0.4704535329188798,-0.23391832955023042,0.6327920744221581,-0.017863872838918923,-0.13496893733397167,0.36038744680166185,1.6879761304662688,0.3972437030547652,3.097206606706352,-0.11532915716857117,0.4339317726253653
| 3,425
|
Ceramide metabolic process
| 10
| 22
| 3.22136
| 0.001276
|
Q96G23,P17900,P06280,O15269,P04062,Q13510,O95470,Q8NCC3,P27544,Q9NRA0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
103,166,139,172,80,17,118,120,125,290
|
172,1095,777,118,80,139,384,1750,166,125,651,1912,1250,17,2662,120,103,606,290,806,1822,544
|
1.7975170034836079,0.13560845959237622,0.3972437030547652,2.2224410858737813,2.62795906725318,2.057946899190213,0.999504346348033,-0.19418721956236745,1.8285620188685285,2.133096436106864,0.5430054701796704,-0.25386051882213734,0.05924575850806966,4.3200361894985715,-0.5801746865595289,2.192759466655405,2.3693825937809168,0.6149138846414414,1.2518646944415734,0.37883671691997084,-0.21402733728023318,0.7216001253197305
| 3,425
|
Steroid binding
| 8
| 24
| 3.21652
| 0.001298
|
O15118,Q9BZF1,P21796,O15173,Q14108,P45880,P04062,P30536
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
97,261,5,229,13,14,80,242
|
514,97,229,980,1898,80,612,916,2946,5,2284,2004,242,1540,934,14,292,1218,13,703,1933,261,757,2040
|
0.7568551780007351,2.3984830795821077,1.4807753146449134,0.2112417984925894,-0.25386051882213734,2.62795906725318,0.5969963442295187,0.2674983597767239,-0.7487318629297377,4.917492659435559,-0.4152809195710186,-0.2938997945656019,1.4159992226041558,-0.09573868680970035,0.24879026863223094,4.496083243944842,1.2352746846067904,0.0784057608191252,4.530920591223999,0.4886526246803302,-0.25386051882213734,1.3343293891978911,0.4339317726253653,-0.2938997945656019
| 3,425
|
Mitochondrial protein import
| 14
| 40
| 3.203966
| 0.001355
|
Q99595,O60830,Q9NX63,P21796,Q9NRP2,Q13505,Q9Y584,Q5JRX3,Q9NS69,Q9Y5J9,Q9Y5J7,Q8N4H5,O14925,Q15388
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
1,2,195,5,295,73,44,460,18,411,188,150,340,416
|
340,740,2,3293,1172,2890,1140,1380,1382,1457,1178,1211,3182,469,664,5,2851,3249,727,73,416,959,460,150,1440,825,1,3257,2368,295,18,195,586,1888,761,44,1170,188,411,911
|
1.10136302234031,0.4339317726253653,5.203448495367863,-1.1875599920679472,0.09751936170847361,-0.7062381065178011,0.11658683691935393,-0.017863872838918923,-0.017863872838918923,-0.056704463496115395,0.09751936170847361,0.0784057608191252,-1.00889493373649,0.8269144177911181,0.5249283688242936,4.917492659435559,-0.6850808626505676,-1.0976844720755563,0.4522133253996353,2.8379436574544386,0.9308994066578831,0.23003816681518965,0.8443364414586735,1.95164797870373,-0.03726011192253851,0.36038744680166185,5.246740467606561,-1.0976844720755563,-0.43569894708233464,1.2352746846067904,4.212879893636516,1.6879761304662688,0.6506311257033517,-0.23391832955023042,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696
| 3,425
|
Mitochondrial transmembrane transport
| 21
| 55
| 3.194053
| 0.001403
|
Q99595,O60830,O95202,P21796,O43772,Q15388,Q9H2D1,Q9BSK2,Q6P4A7,Q8IYU8,P24539,P23786,Q9BQT8,O95831,O75964,P50416,O14925,Q9Y619,P12235,Q96AQ8,P00846
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,2,382,5,143,416,157,288,538,426,547,170,305,557,56,449,340,221,469,240,121
|
340,740,143,2,1833,2890,1140,1496,56,1380,382,557,1457,121,949,1178,3182,469,664,5,170,547,2851,839,3204,449,1674,1249,1185,1721,416,959,538,426,1440,1509,3109,1117,240,825,964,1022,1,1403,305,288,157,1201,1883,2368,834,586,1412,1621,221
|
1.10136302234031,0.4339317726253653,1.9973622966526008,5.203448495367863,-0.23391832955023042,-0.7062381065178011,0.11658683691935393,-0.07619722251063903,3.0567507737172264,-0.017863872838918923,0.999504346348033,0.6861926522306766,-0.056704463496115395,2.162978192726338,0.23003816681518965,0.09751936170847361,-1.00889493373649,0.8269144177911181,0.5249283688242936,4.917492659435559,1.813053367361717,0.7039155427404739,-0.6850808626505676,0.34189565270391015,-1.0309922696079223,0.8617217363584101,-0.15465833406450158,0.05924575850806966,0.09751936170847361,-0.1743976571717926,0.9308994066578831,0.23003816681518965,0.7216001253197305,0.9136591415130947,-0.03726011192253851,-0.07619722251063903,-0.8776777826591424,0.13560845959237622,1.4322394553880162,0.36038744680166185,0.23003816681518965,0.19240090545282404,5.246740467606561,-0.017863872838918923,1.2019963358891592,1.2518646944415734,1.9056938106121482,0.09751936170847361,-0.23391832955023042,-0.43569894708233464,0.36038744680166185,0.6506311257033517,-0.017863872838918923,-0.11532915716857117,1.5290369140825837
| 3,425
|
Lysosome
| 27
| 52
| 3.180435
| 0.001471
|
P16278,P06280,Q14108,P50897,Q13510,Q9NZJ7,P11117,P17900,P10253,Q15904,Q9UMR5,O43681,O75503,Q9Y2T2,P04066,P54802,P07602,P04062,P20645,O14773,P15586,Q93050,P61421,O15118,P10619,Q8NCC3,P06865
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
10,139,13,16,17,552,165,166,421,177,59,311,62,587,576,202,77,80,457,89,345,473,600,97,114,120,384
|
2886,2761,2600,89,97,311,2645,62,80,576,139,384,77,1750,1099,837,421,114,165,950,682,795,3377,345,10,166,457,3289,16,876,202,600,1218,3117,2699,1434,17,13,177,120,1729,473,686,718,3112,552,1339,807,3211,59,587,634
|
-0.7062381065178011,-0.6429435893726733,-0.5593666767876478,2.5139509284160675,2.3984830795821077,1.1685858128764244,-0.5801746865595289,2.947996335155421,2.62795906725318,0.6506311257033517,2.057946899190213,0.999504346348033,2.7125341584739417,-0.19418721956236745,0.13560845959237622,0.34189565270391015,0.9136591415130947,2.2667784467407786,1.8285620188685285,0.23003816681518965,0.5068108281574367,0.37883671691997084,-1.6303721469296955,1.0844726591413512,4.600231735570217,1.8285620188685285,0.8443364414586735,-1.1649875074107834,4.33187072621963,0.304783521666528,1.6247523908291193,0.6149138846414414,0.0784057608191252,-0.8993869388026995,-0.6010399151957811,-0.03726011192253851,4.3200361894985715,4.530920591223999,1.7819528049746483,2.192759466655405,-0.1743976571717926,0.8269144177911181,0.5068108281574367,0.4704535329188798,-0.8776777826591424,0.7039155427404739,0.020785433429236007,0.37883671691997084,-1.0309922696079223,3.002533477096661,0.6506311257033517,0.5790392392161661
| 3,425
|
Vacuolar lumen
| 24
| 66
| 3.158814
| 0.001584
|
P16278,P06280,Q14108,P50897,Q13510,Q9UM22,P11117,O00560,O00584,P17900,Q8NHP8,Q9UMR5,O43681,P54802,P07602,Q8IV08,P04062,Q9BTY2,O14773,P15586,Q9NQ11,Q92820,P10619,P06865
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
10,139,13,16,17,169,165,419,164,166,45,59,311,202,77,79,80,214,89,345,101,238,114,384
|
419,164,2761,89,311,3198,80,576,139,384,1704,1272,77,1750,1665,421,114,165,1835,2767,795,3377,345,10,166,1102,2194,2105,934,3289,2014,1633,16,2431,2066,876,1106,202,3059,2981,1218,1637,2112,2777,1912,1761,17,13,2985,79,2453,45,238,1398,2172,1736,718,214,2039,478,101,3073,552,169,59,2915
|
0.9136591415130947,1.8285620188685285,-0.6429435893726733,2.5139509284160675,1.1685858128764244,-1.0309922696079223,2.62795906725318,0.6506311257033517,2.057946899190213,0.999504346348033,-0.1743976571717926,0.04003907639528579,2.7125341584739417,-0.19418721956236745,-0.15465833406450158,0.9136591415130947,2.2667784467407786,1.8285620188685285,-0.23391832955023042,-0.6429435893726733,0.37883671691997084,-1.6303721469296955,1.0844726591413512,4.600231735570217,1.8285620188685285,0.13560845959237622,-0.3746072665047304,-0.3341478103334249,0.24879026863223094,-1.1649875074107834,-0.2938997945656019,-0.13496893733397167,4.33187072621963,-0.4766991906424338,-0.31399754246940065,0.304783521666528,0.13560845959237622,1.6247523908291193,-0.8344482451084184,-0.7700692108929594,0.0784057608191252,-0.13496893733397167,-0.3341478103334249,-0.6429435893726733,-0.25386051882213734,-0.19418721956236745,4.3200361894985715,4.530920591223999,-0.7700692108929594,2.6703449638891956,-0.4766991906424338,3.230802708999954,1.448448785568869,-0.017863872838918923,-0.3543509374216771,-0.1743976571717926,0.4704535329188798,1.5450638238651857,-0.2938997945656019,0.8269144177911181,2.3839446526313073,-0.8344482451084184,0.7039155427404739,1.8285620188685285,3.002533477096661,-0.7062381065178011
| 3,425
|
Hydrolase activity acting on glycosyl bonds
| 11
| 29
| 3.136692
| 0.001709
|
Q9NUJ1,P17900,P16278,P06280,P54802,O60476,O60502,P04062,Q9BTY2,P06865,O75503
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
3,166,10,139,202,302,267,80,214,384,62
|
2761,1060,302,267,62,80,576,139,384,1750,421,1795,10,166,1537,2950,2651,1668,202,1503,2527,2781,2621,1016,1859,2397,214,3,1484
|
-0.6429435893726733,0.15458450029912923,1.2019963358891592,1.3014399603266282,2.947996335155421,2.62795906725318,0.6506311257033517,2.057946899190213,0.999504346348033,-0.19418721956236745,0.9136591415130947,-0.21402733728023318,4.600231735570217,1.8285620188685285,-0.09573868680970035,-0.7487318629297377,-0.5801746865595289,-0.15465833406450158,1.6247523908291193,-0.07619722251063903,-0.5179207785497725,-0.6429435893726733,-0.5593666767876478,0.19240090545282404,-0.23391832955023042,-0.4561715837491249,1.5450638238651857,5.127245085124307,-0.056704463496115395
| 3,425
|
Sterol binding
| 6
| 18
| 3.136403
| 0.00171
|
O15118,Q9BZF1,P21796,Q14108,P45880,P30536
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
97,261,5,13,14,242
|
97,980,1898,2946,5,2284,2004,242,1540,14,292,1218,13,703,1933,261,757,2040
|
2.3984830795821077,0.2112417984925894,-0.25386051882213734,-0.7487318629297377,4.917492659435559,-0.4152809195710186,-0.2938997945656019,1.4159992226041558,-0.09573868680970035,4.496083243944842,1.2352746846067904,0.0784057608191252,4.530920591223999,0.4886526246803302,-0.25386051882213734,1.3343293891978911,0.4339317726253653,-0.2938997945656019
| 3,425
|
Slc mediated transmembrane transport
| 13
| 25
| 3.1241
| 0.001783
|
P35613,Q70HW3,Q8TB61,Q15043,Q9UBX3,P53985,Q5EBL8,O00400,Q8NEW0,P30825,Q6NXT4,Q9Y6M7,P12235
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
254,133,109,335,111,591,459,86,314,571,348,390,469
|
86,949,2151,1274,469,664,873,571,254,1315,591,1067,335,1015,459,348,1814,133,314,109,1735,1230,1201,111,390
|
2.5425880302168293,0.23003816681518965,-0.3543509374216771,0.04003907639528579,0.8269144177911181,0.5249283688242936,0.304783521666528,0.6684312487998063,1.3507263392996962,0.020785433429236007,0.6327920744221581,0.15458450029912923,1.1182193515975896,0.19240090545282404,0.8443364414586735,1.0844726591413512,-0.21402733728023318,2.10311335779798,1.1685858128764244,2.3108961338926965,-0.1743976571717926,0.0784057608191252,0.09751936170847361,2.2962144810512832,0.999504346348033
| 3,425
|
Glycosaminoglycan metabolism
| 8
| 16
| 3.121302
| 0.001801
|
O43505,P54802,P16278,Q8NCH0,Q8TB61,P15586,P06865,Q7LGA3
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
104,202,10,123,109,345,384,350
|
1206,104,1138,384,1750,345,10,202,350,123,109,783,1162,442,1825,1269
|
0.0784057608191252,2.340187200505293,0.11658683691935393,0.999504346348033,-0.19418721956236745,1.0844726591413512,4.600231735570217,1.6247523908291193,1.0844726591413512,2.162978192726338,2.3108961338926965,0.3972437030547652,0.11658683691935393,0.8790704925764257,-0.21402733728023318,0.05924575850806966
| 3,425
|
Hydrolase activity hydrolyzing o glycosyl compounds
| 10
| 21
| 3.117143
| 0.001826
|
Q9NUJ1,P17900,P16278,P06280,P54802,O60476,O60502,P04062,Q9BTY2,P06865
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
3,166,10,139,202,302,267,80,214,384
|
2761,302,267,80,576,139,384,1750,421,10,166,1668,202,2527,2781,2621,1016,2397,214,3,1484
|
-0.6429435893726733,1.2019963358891592,1.3014399603266282,2.62795906725318,0.6506311257033517,2.057946899190213,0.999504346348033,-0.19418721956236745,0.9136591415130947,4.600231735570217,1.8285620188685285,-0.15465833406450158,1.6247523908291193,-0.5179207785497725,-0.6429435893726733,-0.5593666767876478,0.19240090545282404,-0.4561715837491249,1.5450638238651857,5.127245085124307,-0.056704463496115395
| 3,425
|
Endoplasmic reticulum golgi intermediate compartment
| 17
| 59
| 3.094324
| 0.001973
|
Q96RQ1,O15260,P80303,P49257,Q10472,P24390,Q12907,Q03519,Q15904,Q02818,Q8N511,Q5BJH7,Q9Y282,P56962,Q9Y3B3,Q15363,Q9Y3A6
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
129,99,6,323,270,12,334,236,177,51,53,247,24,249,284,93,253
|
776,1346,99,506,2417,413,613,1706,12,3174,2561,323,343,3023,1247,2519,876,1106,249,1636,6,51,1640,236,2340,270,334,1284,2343,3032,93,177,247,2125,1116,822,53,1867,2358,1731,1079,2669,676,129,645,2460,1001,1777,1568,2463,2308,2232,1825,1303,24,253,284,1452,1701
|
0.3972437030547652,0.001484545851543285,2.3839446526313073,0.7744260494954054,-0.4766991906424338,0.9308994066578831,0.5969963442295187,-0.1743976571717926,4.5656364088713355,-0.9868634800659423,-0.5386155010309926,1.1350418152893942,1.10136302234031,-0.8129269700518783,0.05924575850806966,-0.5179207785497725,0.304783521666528,0.13560845959237622,1.3834254662027163,-0.13496893733397167,4.895159421570552,3.137486998744578,-0.13496893733397167,1.448448785568869,-0.43569894708233464,1.3014399603266282,1.1182193515975896,0.04003907639528579,-0.43569894708233464,-0.8129269700518783,2.4564023437522535,1.7819528049746483,1.3997279417347968,-0.3341478103334249,0.13560845959237622,0.36038744680166185,3.1106528049037374,-0.23391832955023042,-0.43569894708233464,-0.1743976571717926,0.15458450029912923,-0.5801746865595289,0.5249283688242936,2.118117615036976,0.5610423537706956,-0.4766991906424338,0.2112417984925894,-0.19418721956236745,-0.09573868680970035,-0.4766991906424338,-0.4152809195710186,-0.3746072665047304,-0.21402733728023318,0.04003907639528579,3.709233648956977,1.3670916483246272,1.268422139234549,-0.03726011192253851,-0.15465833406450158
| 3,425
|
Receptor
| 22
| 47
| 3.093948
| 0.001975
|
P35613,Q9Y5M8,O00264,P24390,Q14108,Q99720,Q9NS69,Q14739,P60033,Q99523,P11717,P10586,P30825,P55899,Q8WTV0,P20645,O75787,Q9UKV5,O15118,O15173,Q5KU26,P04150
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
254,135,514,12,13,15,18,281,292,686,682,681,571,189,64,457,590,610,97,229,486,612
|
514,811,932,97,229,590,710,612,2320,1097,3077,2688,2002,681,2847,950,682,2003,457,1461,12,1584,571,254,189,292,2523,1148,1391,13,1808,281,1015,486,64,1974,1975,686,1566,15,18,2092,850,610,2373,135,2553
|
0.7568551780007351,0.36038744680166185,0.24879026863223094,2.3984830795821077,1.4807753146449134,0.6327920744221581,0.4704535329188798,0.5969963442295187,-0.43569894708233464,0.13560845959237622,-0.8560317012161593,-0.6010399151957811,-0.2938997945656019,0.5068108281574367,-0.6850808626505676,0.23003816681518965,0.5068108281574367,-0.2938997945656019,0.8443364414586735,-0.056704463496115395,4.5656364088713355,-0.11532915716857117,0.6684312487998063,1.3507263392996962,1.703709953072957,1.2352746846067904,-0.5179207785497725,0.11658683691935393,-0.017863872838918923,4.530920591223999,-0.21402733728023318,1.268422139234549,0.19240090545282404,0.8094554736885617,2.920606361818982,-0.27385423081555665,-0.27385423081555665,0.5068108281574367,-0.09573868680970035,4.355497276975648,4.212879893636516,-0.31399754246940065,0.34189565270391015,0.6149138846414414,-0.43569894708233464,2.10311335779798,-0.5179207785497725
| 3,425
|
Carbohydrate derivative catabolic process
| 13
| 35
| 3.047569
| 0.002307
|
O60658,Q9NUJ1,P17900,P16278,Q13126,P06280,P54802,O60502,P04062,P00813,Q9BTY2,Q9H773,P15586
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,3,166,10,11,139,202,267,80,180,214,55,345
|
1791,267,160,1703,1310,180,80,576,139,384,1750,345,10,166,3150,1800,1540,3412,1279,667,3083,202,1503,1912,11,1561,1512,214,784,3141,55,3,3316,660,3331
|
-0.21402733728023318,1.3014399603266282,1.8594966695461037,-0.1743976571717926,0.020785433429236007,1.7663606487132952,2.62795906725318,0.6506311257033517,2.057946899190213,0.999504346348033,-0.19418721956236745,1.0844726591413512,4.600231735570217,1.8285620188685285,-0.9429962985415629,-0.21402733728023318,-0.09573868680970035,-3.0097998344895656,0.04003907639528579,0.5249283688242936,-0.8560317012161593,1.6247523908291193,-0.07619722251063903,-0.25386051882213734,4.577181521435861,-0.09573868680970035,-0.07619722251063903,1.5450638238651857,0.3972437030547652,-0.9211596241735596,3.0702556610488845,5.127245085124307,-1.2329153395499515,0.5430054701796704,-1.2785547987944277
| 3,425
|
Cholesterol binding
| 6
| 15
| 3.04242
| 0.002347
|
O15118,Q9BZF1,P21796,Q14108,P45880,P30536
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
97,261,5,13,14,242
|
97,980,1898,2946,5,2004,242,1540,14,292,1218,13,261,757,2040
|
2.3984830795821077,0.2112417984925894,-0.25386051882213734,-0.7487318629297377,4.917492659435559,-0.2938997945656019,1.4159992226041558,-0.09573868680970035,4.496083243944842,1.2352746846067904,0.0784057608191252,4.530920591223999,1.3343293891978911,0.4339317726253653,-0.2938997945656019
| 3,425
|
Membrane organization
| 100
| 242
| 3.038352
| 0.002379
|
O15498,Q15070,P50402,P45880,P50897,Q9NS69,Q9Y5P4,Q15392,Q9NZJ7,P30419,Q5XKP0,Q9Y584,O95295,Q9HD42,P46379,Q6NUK4,Q13505,Q9H4A6,Q86XL3,Q9UQB8,Q15629,Q15363,Q15041,Q96CP7,O15118,Q9NQ11,Q9BUR5,Q8NHH9,Q16611,Q9ULX6,Q92734,P31751,Q96AA3,Q9P2W9,Q96GC9,O75844,P49840,P33527,O95721,Q9UEU0,Q8N6H7,Q8N4V1,Q9Y5J7,Q6UXV4,Q9NX63,P31749,Q9Y3E7,Q9H3K2,P51790,Q9NQC3,Q8NFQ8,Q9NZD2,P52789,P16615,O60499,Q9Y512,O14737,Q15006,O15027,P30536,P48739,P50570,P56962,Q9BZF1,O94901,Q8N8Q8,Q9NR31,Q9H6H4,Q9H5V9,O15155,Q15436,P98194,P49841,Q8N1F7,P04083,Q8WUH2,Q4KMQ2,Q53EZ4,O60343,Q9BSR8,O95249,Q5J8M3,O43681,O43402,P51809,P08183,P49755,Q9Y5X1,O95235,O95202,O43752,Q9Y5J9,Q8IWA4,P49069,Q96A33,P41440,Q9BZG1,P12235,O60313,O43760
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
506,520,517,14,16,18,544,36,552,549,561,44,556,573,63,581,73,596,78,82,84,93,601,98,97,101,621,632,629,658,656,653,152,153,676,154,667,666,663,706,699,186,188,696,195,693,722,720,204,210,731,736,725,724,225,761,234,748,739,242,743,745,249,261,263,272,789,787,786,776,781,780,779,279,778,801,799,298,794,301,303,821,311,812,819,322,343,372,383,382,379,411,433,431,441,458,477,469,482,481
|
3157,2886,1306,1745,1378,2600,977,234,1528,1942,739,97,776,2238,1346,1747,506,812,1420,311,379,481,1994,482,794,1575,225,1238,2477,2417,1172,1240,1242,154,853,1380,3181,263,2278,913,382,383,303,2845,556,2419,1245,663,1901,778,2805,1533,949,1704,1665,2946,322,1212,1424,1835,469,724,1313,2558,3348,1797,2284,3132,549,242,693,653,666,2732,2107,3249,458,1843,2483,2734,14,2012,63,1588,743,431,343,667,779,517,745,16,2610,3116,204,819,725,1317,2811,1546,3217,249,877,2020,2569,2900,1218,1108,1548,2289,780,898,1964,1912,2957,1505,1110,2820,1284,2780,73,2071,3236,1152,1111,1644,1188,748,601,520,2534,1810,2395,93,36,781,84,629,820,959,799,298,2662,1596,821,1438,1769,561,581,696,2355,2665,78,1326,433,1862,2218,279,1972,186,699,1771,272,1605,3368,731,632,801,1562,1198,1117,1867,3240,2358,1974,656,441,152,98,2934,1563,676,1737,3292,301,1690,621,2460,261,477,1479,720,596,786,787,2142,573,1372,101,210,789,3407,18,1653,2046,195,736,552,2270,3089,1128,2369,1785,153,1337,706,1004,1825,2094,2049,2941,658,1167,2412,973,2640,82,1168,1888,1234,1235,1657,722,1621,761,44,1170,188,411,911,544,372
|
-0.9648974270030561,-0.7062381065178011,0.020785433429236007,-0.19418721956236745,-0.017863872838918923,-0.5593666767876478,0.2112417984925894,1.448448785568869,-0.09573868680970035,-0.27385423081555665,0.4339317726253653,2.3984830795821077,0.3972437030547652,-0.39491714390968624,0.001484545851543285,-0.19418721956236745,0.7744260494954054,0.36038744680166185,-0.03726011192253851,1.1685858128764244,0.999504346348033,0.8094554736885617,-0.2938997945656019,0.8094554736885617,0.37883671691997084,-0.11532915716857117,1.4968927991314636,0.05924575850806966,-0.4972821326535668,-0.4766991906424338,0.09751936170847361,0.05924575850806966,0.05924575850806966,1.9056938106121482,0.32336109245226435,-0.017863872838918923,-1.00889493373649,1.3179006469481906,-0.4152809195710186,0.2674983597767239,0.999504346348033,0.999504346348033,1.2019963358891592,-0.6850808626505676,0.6861926522306766,-0.4766991906424338,0.05924575850806966,0.5249283688242936,-0.25386051882213734,0.3972437030547652,-0.663982825714329,-0.09573868680970035,0.23003816681518965,-0.1743976571717926,-0.15465833406450158,-0.7487318629297377,1.1350418152893942,0.0784057608191252,-0.03726011192253851,-0.23391832955023042,0.8269144177911181,0.4522133253996353,0.020785433429236007,-0.5386155010309926,-1.3939257358204213,-0.21402733728023318,-0.4152809195710186,-0.9211596241735596,0.7039155427404739,1.4159992226041558,0.4886526246803302,0.5430054701796704,0.5249283688242936,-0.6219627517160322,-0.3341478103334249,-1.0976844720755563,0.8443364414586735,-0.23391832955023042,-0.4972821326535668,-0.6219627517160322,4.496083243944842,-0.2938997945656019,2.947996335155421,-0.11532915716857117,0.4339317726253653,0.8963828986355812,1.10136302234031,0.5249283688242936,0.3972437030547652,0.7568551780007351,0.4339317726253653,4.33187072621963,-0.5593666767876478,-0.8993869388026995,1.6088736896093438,0.36038744680166185,0.4522133253996353,0.020785433429236007,-0.663982825714329,-0.09573868680970035,-1.0531559749508097,1.3834254662027163,0.304783521666528,-0.2938997945656019,-0.5386155010309926,-0.7062381065178011,0.0784057608191252,0.13560845959237622,-0.09573868680970035,-0.4152809195710186,0.3972437030547652,0.2861626937330696,-0.27385423081555665,-0.25386051882213734,-0.7487318629297377,-0.07619722251063903,0.13560845959237622,-0.663982825714329,0.04003907639528579,-0.6429435893726733,2.8379436574544386,-0.31399754246940065,-1.075386542805351,0.11658683691935393,0.13560845959237622,-0.13496893733397167,0.09751936170847361,0.4339317726253653,0.6149138846414414,0.7568551780007351,-0.5179207785497725,-0.21402733728023318,-0.4561715837491249,2.4564023437522535,3.3886394720355844,0.3972437030547652,2.599591402744298,0.5790392392161661,0.36038744680166185,0.23003816681518965,0.37883671691997084,1.2186519515565648,-0.5801746865595289,-0.11532915716857117,0.36038744680166185,-0.03726011192253851,-0.19418721956236745,0.6861926522306766,0.6506311257033517,0.4886526246803302,-0.43569894708233464,-0.5801746865595289,2.6703449638891956,0.020785433429236007,0.8963828986355812,-0.23391832955023042,-0.3746072665047304,1.2849471759441964,-0.27385423081555665,1.7194151890935954,0.4886526246803302,-0.19418721956236745,1.3014399603266282,-0.11532915716857117,-1.5586135678457116,0.4522133253996353,0.5790392392161661,0.37883671691997084,-0.09573868680970035,0.09751936170847361,0.13560845959237622,-0.23391832955023042,-1.075386542805351,-0.43569894708233464,-0.27385423081555665,0.5430054701796704,0.8790704925764257,1.9210387080998343,2.3984830795821077,-0.7274549681465066,-0.09573868680970035,0.5249283688242936,-0.1743976571717926,-1.1649875074107834,1.2186519515565648,-0.15465833406450158,0.5969963442295187,-0.4766991906424338,1.3343293891978911,0.8269144177911181,-0.056704463496115395,0.4704535329188798,0.6327920744221581,0.3972437030547652,0.3972437030547652,-0.3341478103334249,0.6684312487998063,0.001484545851543285,2.3839446526313073,1.5610608196920086,0.3972437030547652,-2.3381474618542457,4.212879893636516,-0.13496893733397167,-0.2938997945656019,1.6879761304662688,0.4522133253996353,0.7039155427404739,-0.39491714390968624,-0.8560317012161593,0.13560845959237622,-0.43569894708233464,-0.19418721956236745,1.9210387080998343,0.020785433429236007,0.4886526246803302,0.2112417984925894,-0.21402733728023318,-0.31399754246940065,-0.2938997945656019,-0.7274549681465066,0.5430054701796704,0.11658683691935393,-0.4561715837491249,0.23003816681518965,-0.5593666767876478,2.62795906725318,0.11658683691935393,-0.23391832955023042,0.0784057608191252,0.0784057608191252,-0.13496893733397167,0.4704535329188798,-0.11532915716857117,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696,0.7216001253197305,1.0335956619699211
| 3,425
|
Lytic vacuole organization
| 14
| 29
| 3.028355
| 0.002459
|
P11117,P54802,P10253,Q14108,Q96ED9,P50897,P04062,Q96AX1,Q12768,Q8N511,O95295,Q9BZG1,O14773,O75503
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
165,202,421,13,274,16,80,209,498,53,556,477,89,62
|
2886,89,62,590,556,80,1750,421,165,1181,16,2610,202,1804,498,13,961,53,209,274,1263,477,907,3384,2046,806,1783,1168,722
|
-0.7062381065178011,2.5139509284160675,2.947996335155421,0.6327920744221581,0.6861926522306766,2.62795906725318,-0.19418721956236745,0.9136591415130947,1.8285620188685285,0.09751936170847361,4.33187072621963,-0.5593666767876478,1.6247523908291193,-0.21402733728023318,0.7919594158846363,4.530920591223999,0.23003816681518965,3.1106528049037374,1.5610608196920086,1.3014399603266282,0.05924575850806966,0.8269144177911181,0.2861626937330696,-1.7271928388381075,-0.2938997945656019,0.37883671691997084,-0.19418721956236745,0.11658683691935393,0.4704535329188798
| 3,425
|
Alcohol binding
| 6
| 18
| 3.022756
| 0.002505
|
O15118,Q9BZF1,P21796,Q14108,P45880,P30536
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
97,261,5,13,14,242
|
3343,97,1061,980,1898,2946,5,2004,1799,242,1540,14,292,1218,13,261,757,2040
|
-1.3707038556261375,2.3984830795821077,0.15458450029912923,0.2112417984925894,-0.25386051882213734,-0.7487318629297377,4.917492659435559,-0.2938997945656019,-0.21402733728023318,1.4159992226041558,-0.09573868680970035,4.496083243944842,1.2352746846067904,0.0784057608191252,4.530920591223999,1.3343293891978911,0.4339317726253653,-0.2938997945656019
| 3,425
|
Disproportionate short stature
| 12
| 26
| 3.014546
| 0.002574
|
Q9Y366,Q15125,P10644,Q15392,O00116,P16278,Q9UHX1,Q6DKJ4,Q03164,Q32P28,Q14739,Q7LGA3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
321,151,163,36,199,10,401,367,211,119,281,350
|
199,2238,3145,412,163,10,2893,1181,1905,211,614,1188,281,2704,151,36,119,367,350,996,942,3127,1977,972,401,321
|
1.6564222106812256,-0.39491714390968624,-0.9429962985415629,0.9308994066578831,1.844043079409893,4.600231735570217,-0.7062381065178011,0.09751936170847361,-0.25386051882213734,1.5450638238651857,0.5969963442295187,0.09751936170847361,1.268422139234549,-0.6010399151957811,1.9210387080998343,3.3886394720355844,2.2224410858737813,1.0335956619699211,1.0844726591413512,0.2112417984925894,0.24879026863223094,-0.8993869388026995,-0.27385423081555665,0.23003816681518965,0.9652727380057537,1.1518305804680873
| 3,425
|
Abnormal circulating cholesterol concentration
| 14
| 33
| 3.010864
| 0.002605
|
Q9UJS0,O75845,Q15125,Q15392,Q9NZJ7,P50402,Q15800,Q13045,P07602,Q15904,Q8N511,Q14739,P57740,P34913
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
586,162,151,36,552,517,43,312,77,177,53,281,436,470
|
1172,162,1901,1628,77,470,1009,3289,2015,517,2566,436,1218,989,312,1551,281,151,36,1915,43,177,2496,53,2497,824,1690,1371,647,552,972,586,1205
|
0.09751936170847361,1.844043079409893,-0.25386051882213734,-0.13496893733397167,2.7125341584739417,0.8269144177911181,0.19240090545282404,-1.1649875074107834,-0.2938997945656019,0.7568551780007351,-0.5386155010309926,0.8790704925764257,0.0784057608191252,0.2112417984925894,1.1685858128764244,-0.09573868680970035,1.268422139234549,1.9210387080998343,3.3886394720355844,-0.25386051882213734,3.2440577254623797,1.7819528049746483,-0.4972821326535668,3.1106528049037374,-0.4972821326535668,0.36038744680166185,-0.15465833406450158,0.001484545851543285,0.5610423537706956,0.7039155427404739,0.23003816681518965,0.6506311257033517,0.09751936170847361
| 3,425
|
Intrinsic component of mitochondrial membrane
| 29
| 55
| 3.00595
| 0.002648
|
Q99595,O60830,Q15070,Q9UG56,Q8N8Q8,Q15388,Q6P4A7,Q5XKP0,Q8IWA4,Q16134,Q9NWR8,Q9Y2R0,Q6UXV4,P50336,Q9NX63,P50416,Q9H3K2,Q13505,Q9H9P8,O43819,O14925,P12235,Q9Y512,Q9BUR5,Q9BUB7,P57105,Q96AQ8,Q16611,Q9BWH2
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,2,520,791,272,416,538,561,433,304,834,54,696,818,195,449,720,73,597,709,340,469,761,621,620,483,240,629,388
|
340,709,2,1172,1175,1380,913,1457,469,3249,818,449,483,1721,73,520,416,304,629,820,2662,1596,561,538,696,433,1862,2218,272,1509,1362,240,964,1022,1,1403,620,621,388,2366,2835,720,1883,597,1406,2044,1653,834,195,791,1130,54,892,1621,761
|
1.10136302234031,0.4704535329188798,5.203448495367863,0.09751936170847361,0.09751936170847361,-0.017863872838918923,0.2674983597767239,-0.056704463496115395,0.8269144177911181,-1.0976844720755563,0.36038744680166185,0.8617217363584101,0.8094554736885617,-0.1743976571717926,2.8379436574544386,0.7568551780007351,0.9308994066578831,1.2019963358891592,0.5790392392161661,0.36038744680166185,-0.5801746865595289,-0.11532915716857117,0.6861926522306766,0.7216001253197305,0.4886526246803302,0.8963828986355812,-0.23391832955023042,-0.3746072665047304,1.3014399603266282,-0.07619722251063903,0.001484545851543285,1.4322394553880162,0.23003816681518965,0.19240090545282404,5.246740467606561,-0.017863872838918923,0.5969963442295187,0.5969963442295187,0.999504346348033,-0.43569894708233464,-0.663982825714329,0.4704535329188798,-0.23391832955023042,0.6327920744221581,-0.017863872838918923,-0.2938997945656019,-0.13496893733397167,0.36038744680166185,1.6879761304662688,0.3972437030547652,0.13560845959237622,3.097206606706352,0.304783521666528,-0.11532915716857117,0.4339317726253653
| 3,425
|
Cholesterol biosynthesis
| 7
| 18
| 2.990145
| 0.002788
|
O75845,Q15392,Q14739,Q15800,Q16850,Q15125,Q9BWD1
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
162,36,281,43,46,151,27
|
162,894,1038,1009,1500,2927,2116,2575,407,281,151,2346,36,1915,43,46,27,972
|
1.844043079409893,0.2861626937330696,0.17351522707522676,0.19240090545282404,-0.07619722251063903,-0.7274549681465066,-0.3341478103334249,-0.5386155010309926,0.9481038780076505,1.268422139234549,1.9210387080998343,-0.43569894708233464,3.3886394720355844,-0.25386051882213734,3.2440577254623797,3.1775938115320623,3.633270890999699,0.23003816681518965
| 3,425
|
Protein transmembrane transport
| 9
| 26
| 2.989915
| 0.002791
|
Q99595,O60830,Q9Y584,Q9NS69,P49755,Q15629,O14925,O75298,Q9UGP8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,2,44,18,343,84,340,403,389
|
340,740,2,403,1577,1380,557,1457,3182,653,343,2658,2570,2900,798,416,84,959,1440,825,1514,1,2368,18,389,44
|
1.10136302234031,0.4339317726253653,5.203448495367863,0.9481038780076505,-0.11532915716857117,-0.017863872838918923,0.6861926522306766,-0.056704463496115395,-1.00889493373649,0.5430054701796704,1.10136302234031,-0.5801746865595289,-0.5386155010309926,-0.7062381065178011,0.37883671691997084,0.9308994066578831,2.599591402744298,0.23003816681518965,-0.03726011192253851,0.36038744680166185,-0.07619722251063903,5.246740467606561,-0.43569894708233464,4.212879893636516,0.999504346348033,3.2440577254623797
| 3,425
|
Diseases of glycosylation
| 7
| 21
| 2.974603
| 0.002934
|
O43505,Q9BT22,P16278,P10619,Q96AA3,Q9NP73,Q8NCH0
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
104,361,10,114,152,376,123
|
104,1061,2477,384,1750,114,10,1429,2608,2566,1467,2781,1808,1076,123,783,152,1162,361,376,1205
|
2.340187200505293,0.15458450029912923,-0.4972821326535668,0.999504346348033,-0.19418721956236745,2.2667784467407786,4.600231735570217,-0.03726011192253851,-0.5593666767876478,-0.5386155010309926,-0.056704463496115395,-0.6429435893726733,-0.21402733728023318,0.15458450029912923,2.162978192726338,0.3972437030547652,1.9210387080998343,0.11658683691935393,1.0505891507074792,1.0165674522554908,0.09751936170847361
| 3,425
|
transporter
| 25
| 61
| 2.964687
| 0.00303
|
Q99595,O15321,O60830,O00505,Q15070,Q8N8Q8,O43772,Q9NUN5,Q8N1F7,Q9H2D1,Q9NR77,Q92973,Q9Y584,P57740,O43681,Q9HAV4,Q567V2,P52294,P53985,P41440,Q9Y619,Q99805,Q6NXT4,Q6PML9,Q9HD45
|
Functions
|
Panther Protein class
|
panther_protein_class
|
1,378,2,377,520,272,143,145,279,157,29,286,44,436,311,319,75,205,591,458,221,606,348,349,362
|
1005,377,2600,3171,1033,378,611,740,311,143,2,1242,2101,1499,1277,458,743,2249,1010,205,1635,1674,591,2199,1280,3217,436,2900,1435,1320,520,75,3394,348,349,1158,279,272,2082,2084,673,753,286,2584,1262,889,1,606,1230,2226,1518,157,319,362,29,145,1695,1412,44,1660,221
|
0.19240090545282404,0.999504346348033,-0.5593666767876478,-0.9868634800659423,0.17351522707522676,0.999504346348033,0.5969963442295187,0.4339317726253653,1.1685858128764244,1.9973622966526008,5.203448495367863,0.05924575850806966,-0.3341478103334249,-0.07619722251063903,0.04003907639528579,0.8443364414586735,0.4339317726253653,-0.39491714390968624,0.19240090545282404,1.6088736896093438,-0.13496893733397167,-0.15465833406450158,0.6327920744221581,-0.3746072665047304,0.04003907639528579,-1.0531559749508097,0.8790704925764257,-0.7062381065178011,-0.03726011192253851,0.020785433429236007,0.7568551780007351,2.7963313322340135,-1.8749638166066318,1.0844726591413512,1.0844726591413512,0.11658683691935393,1.2849471759441964,1.3014399603266282,-0.31399754246940065,-0.31399754246940065,0.5249283688242936,0.4339317726253653,1.2518646944415734,-0.5386155010309926,0.05924575850806966,0.304783521666528,5.246740467606561,0.6149138846414414,0.0784057608191252,-0.3746072665047304,-0.07619722251063903,1.9056938106121482,1.1518305804680873,1.0505891507074792,3.59506153369759,1.9973622966526008,-0.15465833406450158,-0.017863872838918923,3.2440577254623797,-0.13496893733397167,1.5290369140825837
| 3,425
|
Glycosphingolipid metabolism
| 9
| 17
| 2.959599
| 0.00308
|
P17900,P16278,P06280,P07602,P04062,Q13510,P10619,P06865,O43681
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
166,10,139,77,80,17,114,384,311
|
1489,311,80,139,384,77,1750,114,3377,10,166,17,394,1931,1822,736,552
|
-0.07619722251063903,1.1685858128764244,2.62795906725318,2.057946899190213,0.999504346348033,2.7125341584739417,-0.19418721956236745,2.2667784467407786,-1.6303721469296955,4.600231735570217,1.8285620188685285,4.3200361894985715,0.9824061676177961,-0.25386051882213734,-0.21402733728023318,0.4522133253996353,0.7039155427404739
| 3,425
|
Protein insertion into membrane
| 13
| 33
| 2.953348
| 0.003143
|
Q15070,Q8N8Q8,Q9Y584,O14737,P49069,Q9NS69,Q9Y5J9,Q15629,Q96A33,Q8N4V1,O43681,Q9Y5J7,P46379
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
520,272,44,234,431,18,411,84,441,186,311,188,63
|
234,812,311,1994,1380,1665,549,2732,63,431,2900,748,520,84,2662,821,2355,186,1771,272,1117,441,1372,18,3089,1128,1888,761,44,1170,188,411,911
|
1.448448785568869,0.36038744680166185,1.1685858128764244,-0.2938997945656019,-0.017863872838918923,-0.15465833406450158,0.7039155427404739,-0.6219627517160322,2.947996335155421,0.8963828986355812,-0.7062381065178011,0.4339317726253653,0.7568551780007351,2.599591402744298,-0.5801746865595289,0.36038744680166185,-0.43569894708233464,1.7194151890935954,-0.19418721956236745,1.3014399603266282,0.13560845959237622,0.8790704925764257,0.001484545851543285,4.212879893636516,-0.8560317012161593,0.13560845959237622,-0.23391832955023042,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696
| 3,425
|
Vacuole
| 57
| 221
| 2.95119
| 0.003166
|
O15321,Q9UHG3,P16278,Q9BXS4,P06280,Q14108,P50897,Q13510,Q9NUN5,P30511,Q9NRA0,Q9UM22,P42785,P11117,P17900,O00584,O00560,P10253,Q8NHP8,P00813,Q8N511,Q9UMR5,O43681,Q8NCG7,O75503,Q8WTV0,Q5BJF2,Q96A57,Q15165,P54802,P51790,P07602,Q8IV08,P04062,Q96AX1,Q15043,P20645,P41440,Q9BTY2,Q9NQX7,Q9H7Z7,O14773,P15586,Q93050,Q9UIQ6,Q9NX40,O15118,O15260,Q9NQ11,P07384,Q07065,P42892,Q92820,P10619,Q8NCC3,P56962,P06865
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
378,4,10,138,139,13,16,17,145,28,290,169,37,165,166,164,419,421,45,180,53,59,311,451,62,64,65,452,72,202,204,77,79,80,209,335,457,458,214,215,478,89,345,473,95,351,97,99,101,352,484,107,238,114,120,249,384
|
3157,2886,419,164,2761,2600,89,97,99,378,1747,2476,1420,311,2645,1944,690,2992,2843,1946,741,62,590,853,1579,663,2764,3198,180,80,576,2378,139,384,1704,352,1272,77,1750,1665,2946,2151,1949,1212,1099,2001,421,114,165,1835,2767,950,795,3377,345,10,3275,166,838,457,1102,982,2104,3184,1103,2950,3174,2194,2426,2105,28,1955,1276,1384,1008,934,3289,1841,2331,458,1181,37,107,2897,1588,2014,1633,639,16,2431,2656,2432,2610,1634,204,819,2066,876,1184,1106,202,3059,3217,249,1011,2020,1636,1804,2981,600,1218,3117,2158,1637,2112,2699,765,2777,3119,1912,484,1148,3298,1434,2957,1505,669,1761,17,2619,1358,13,2985,335,72,749,65,961,750,79,3256,885,53,2453,120,451,700,45,64,1198,2583,733,238,473,500,452,209,1398,2934,2584,676,1263,1000,2172,686,1736,718,2225,1737,2909,847,214,3424,2039,138,3112,3337,564,1299,1479,3225,478,3364,1651,907,1330,573,101,215,290,1166,3384,145,2046,351,3073,552,2270,2369,1783,1885,1785,706,4,1339,95,169,3012,59,1167,973,2915,1168,1620,587,1657,722,634,1031,975,1343
|
-0.9648974270030561,-0.7062381065178011,0.9136591415130947,1.8285620188685285,-0.6429435893726733,-0.5593666767876478,2.5139509284160675,2.3984830795821077,2.3839446526313073,0.999504346348033,-0.19418721956236745,-0.4972821326535668,-0.03726011192253851,1.1685858128764244,-0.5801746865595289,-0.27385423081555665,0.4886526246803302,-0.79146743676524,-0.6850808626505676,-0.27385423081555665,0.4339317726253653,2.947996335155421,0.6327920744221581,0.32336109245226435,-0.11532915716857117,0.5249283688242936,-0.6429435893726733,-1.0309922696079223,1.7663606487132952,2.62795906725318,0.6506311257033517,-0.4561715837491249,2.057946899190213,0.999504346348033,-0.1743976571717926,1.0675480922862204,0.04003907639528579,2.7125341584739417,-0.19418721956236745,-0.15465833406450158,-0.7487318629297377,-0.3543509374216771,-0.27385423081555665,0.0784057608191252,0.13560845959237622,-0.2938997945656019,0.9136591415130947,2.2667784467407786,1.8285620188685285,-0.23391832955023042,-0.6429435893726733,0.23003816681518965,0.37883671691997084,-1.6303721469296955,1.0844726591413512,4.600231735570217,-1.142484440376989,1.8285620188685285,0.34189565270391015,0.8443364414586735,0.13560845959237622,0.2112417984925894,-0.3341478103334249,-1.00889493373649,0.13560845959237622,-0.7487318629297377,-0.9868634800659423,-0.3746072665047304,-0.4766991906424338,-0.3341478103334249,3.6205514552672318,-0.27385423081555665,0.04003907639528579,-0.017863872838918923,0.19240090545282404,0.24879026863223094,-1.1649875074107834,-0.23391832955023042,-0.43569894708233464,0.8443364414586735,0.09751936170847361,3.3755871954184276,2.325553674617119,-0.7062381065178011,-0.11532915716857117,-0.2938997945656019,-0.13496893733397167,0.5610423537706956,4.33187072621963,-0.4766991906424338,-0.5801746865595289,-0.4766991906424338,-0.5593666767876478,-0.13496893733397167,1.6088736896093438,0.36038744680166185,-0.31399754246940065,0.304783521666528,0.09751936170847361,0.13560845959237622,1.6247523908291193,-0.8344482451084184,-1.0531559749508097,1.3834254662027163,0.19240090545282404,-0.2938997945656019,-0.13496893733397167,-0.21402733728023318,-0.7700692108929594,0.6149138846414414,0.0784057608191252,-0.8993869388026995,-0.3543509374216771,-0.13496893733397167,-0.3341478103334249,-0.6010399151957811,0.41560864305026346,-0.6429435893726733,-0.8993869388026995,-0.25386051882213734,0.8094554736885617,0.11658683691935393,-1.1875599920679472,-0.03726011192253851,-0.7487318629297377,-0.07619722251063903,0.5249283688242936,-0.19418721956236745,4.3200361894985715,-0.5593666767876478,0.001484545851543285,4.530920591223999,-0.7700692108929594,1.1182193515975896,2.8517725495914763,0.4339317726253653,2.9068807648891117,0.23003816681518965,0.4339317726253653,2.6703449638891956,-1.0976844720755563,0.304783521666528,3.1106528049037374,-0.4766991906424338,2.192759466655405,0.8617217363584101,0.4886526246803302,3.230802708999954,2.920606361818982,0.09751936170847361,-0.5386155010309926,0.4522133253996353,1.448448785568869,0.8269144177911181,0.7919594158846363,0.8617217363584101,1.5610608196920086,-0.017863872838918923,-0.7274549681465066,-0.5386155010309926,0.5249283688242936,0.05924575850806966,0.2112417984925894,-0.3543509374216771,0.5068108281574367,-0.1743976571717926,0.4704535329188798,-0.3746072665047304,-0.1743976571717926,-0.7062381065178011,0.34189565270391015,1.5450638238651857,-16.25099160407786,-0.2938997945656019,2.0730281075790966,-0.8776777826591424,-1.32448279287036,0.6861926522306766,0.04003907639528579,-0.056704463496115395,-1.0531559749508097,0.8269144177911181,-1.5111725380859105,-0.13496893733397167,0.2861626937330696,0.020785433429236007,0.6684312487998063,2.3839446526313073,1.5450638238651857,1.2518646944415734,0.11658683691935393,-1.7271928388381075,1.9973622966526008,-0.2938997945656019,1.0844726591413512,-0.8344482451084184,0.7039155427404739,-0.39491714390968624,-0.43569894708233464,-0.19418721956236745,-0.23391832955023042,-0.19418721956236745,0.4886526246803302,5.094411977540183,0.020785433429236007,2.441957508201226,1.8285620188685285,-0.79146743676524,3.002533477096661,0.11658683691935393,0.23003816681518965,-0.7062381065178011,0.11658683691935393,-0.11532915716857117,0.6506311257033517,-0.13496893733397167,0.4704535329188798,0.5790392392161661,0.19240090545282404,0.23003816681518965,0.020785433429236007
| 3,425
|
Sphingolipid metabolism
| 6
| 9
| 2.923448
| 0.003462
|
P17900,P07602,P04062,Q13510,O95470,Q9NZ01
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
166,77,80,17,118,94
|
172,1095,118,80,77,166,527,17,94
|
1.7975170034836079,0.13560845959237622,2.2224410858737813,2.62795906725318,2.7125341584739417,1.8285620188685285,0.7392466032253644,4.3200361894985715,2.4564023437522535
| 3,425
|
Membrane lipid biosynthetic process
| 12
| 27
| 2.921425
| 0.003484
|
Q9P035,P27544,Q96G23,O43292,O15269,P04062,Q13510,Q06136,O95470,Q8NBX0,Q9Y2B2,Q9NRA0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
585,125,103,480,172,80,17,527,118,122,456,290
|
172,1095,480,1061,118,80,2284,125,1912,527,1250,17,2662,1597,697,122,1048,1924,103,829,606,2588,290,1822,585,2369,456
|
1.7975170034836079,0.13560845959237622,0.8094554736885617,0.15458450029912923,2.2224410858737813,2.62795906725318,-0.4152809195710186,2.133096436106864,-0.25386051882213734,0.7392466032253644,0.05924575850806966,4.3200361894985715,-0.5801746865595289,-0.11532915716857117,0.4886526246803302,2.162978192726338,0.17351522707522676,-0.25386051882213734,2.3693825937809168,0.36038744680166185,0.6149138846414414,-0.5386155010309926,1.2518646944415734,-0.21402733728023318,0.6506311257033517,-0.43569894708233464,0.8617217363584101
| 3,425
|
Molecular transducer activity
| 22
| 45
| 2.914718
| 0.00356
|
Q14108,Q99720,P49327,Q6NYC1,Q9NRA0,O43813,Q99523,Q9UIW2,P11717,Q8WTV0,P20645,O75575,Q15629,O75787,Q9UKV5,O15118,O15173,Q5KU26,P04150,P30536,Q08722,Q9UGP8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
13,15,526,537,290,545,686,567,682,64,457,589,84,590,610,97,229,486,612,242,628,389
|
811,932,97,229,545,589,590,612,2320,681,2847,682,457,1584,242,857,2653,526,3026,1148,628,1391,13,84,1015,1396,486,537,939,64,1974,1975,1514,686,15,1083,290,3346,2092,2839,850,389,567,610,1343
|
0.36038744680166185,0.24879026863223094,2.3984830795821077,1.4807753146449134,0.7039155427404739,0.6327920744221581,0.6327920744221581,0.5969963442295187,-0.43569894708233464,0.5068108281574367,-0.6850808626505676,0.5068108281574367,0.8443364414586735,-0.11532915716857117,1.4159992226041558,0.32336109245226435,-0.5801746865595289,0.7392466032253644,-0.8129269700518783,0.11658683691935393,0.5790392392161661,-0.017863872838918923,4.530920591223999,2.599591402744298,0.19240090545282404,-0.017863872838918923,0.8094554736885617,0.7216001253197305,0.24879026863223094,2.920606361818982,-0.27385423081555665,-0.27385423081555665,-0.07619722251063903,0.5068108281574367,4.355497276975648,0.15458450029912923,1.2518646944415734,-1.3707038556261375,-0.31399754246940065,-0.663982825714329,0.34189565270391015,0.999504346348033,0.6861926522306766,0.6149138846414414,0.020785433429236007
| 3,425
|
Anion transport
| 33
| 73
| 2.910075
| 0.003613
|
Q9UHG3,P21796,P45880,Q9Y5P4,O60831,Q9H2D1,P33527,Q9NZJ7,Q9BQT8,O43681,P30825,Q9UJS0,Q9C0H2,P08183,P51790,P07602,P14174,Q15043,Q9H0H5,P53985,P41440,Q6NUK1,O00400,Q9Y619,Q9Y277,Q15041,P12235,Q8TB61,Q9UBX3,P30536,Q14728,Q08722,Q9Y6M7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,5,14,544,402,157,666,552,305,311,571,586,70,322,204,77,333,335,464,591,458,604,86,221,220,601,469,109,111,242,366,628,390
|
2315,86,1528,2514,311,813,814,402,1140,2150,778,949,2320,77,322,2151,2923,1274,469,664,333,5,871,242,571,666,458,14,204,1674,591,2199,1067,1721,1550,628,1250,366,601,335,1015,1679,799,3394,604,1814,3256,109,1022,1735,803,1230,305,968,70,464,157,1201,1883,1406,1330,736,552,111,4,2370,586,220,1169,544,221,3333,390
|
-0.43569894708233464,2.5425880302168293,-0.09573868680970035,-0.5179207785497725,1.1685858128764244,0.36038744680166185,0.36038744680166185,0.9481038780076505,0.11658683691935393,-0.3543509374216771,0.3972437030547652,0.23003816681518965,-0.43569894708233464,2.7125341584739417,1.1350418152893942,-0.3543509374216771,-0.7274549681465066,0.04003907639528579,0.8269144177911181,0.5249283688242936,1.1182193515975896,4.917492659435559,0.304783521666528,1.4159992226041558,0.6684312487998063,0.5249283688242936,0.8443364414586735,4.496083243944842,1.6088736896093438,-0.15465833406450158,0.6327920744221581,-0.3746072665047304,0.15458450029912923,-0.1743976571717926,-0.09573868680970035,0.5790392392161661,0.05924575850806966,1.0335956619699211,0.6149138846414414,1.1182193515975896,0.19240090545282404,-0.15465833406450158,0.37883671691997084,-1.8749638166066318,0.6149138846414414,-0.21402733728023318,-1.0976844720755563,2.3108961338926965,0.19240090545282404,-0.1743976571717926,0.37883671691997084,0.0784057608191252,1.2019963358891592,0.23003816681518965,2.8655806296701516,0.8443364414586735,1.9056938106121482,0.09751936170847361,-0.23391832955023042,-0.017863872838918923,0.020785433429236007,0.4522133253996353,0.7039155427404739,2.2962144810512832,5.094411977540183,-0.43569894708233464,0.6506311257033517,1.5290369140825837,0.11658683691935393,0.7216001253197305,1.5290369140825837,-1.3014824482535676,0.999504346348033
| 3,425
|
Ion transmembrane transporter activity
| 45
| 115
| 2.909849
| 0.003616
|
O95202,P21796,Q70HW3,Q7KZN9,P45880,O43772,Q9H2D1,Q6P4A7,P24539,Q9UDW1,Q9BQT8,Q13423,P35670,P36383,O75964,Q8NEW0,Q8N4V1,P30825,O43681,Q9UJS0,Q9C0H2,Q8N1S5,P51790,Q15043,P53985,P41440,Q6NUK1,O00400,Q9Y619,Q9Y277,Q93050,Q6NXT4,Q6PML9,P12235,P61421,P20674,Q9NQ11,Q96ES6,Q8TB61,Q9UBX3,P20020,Q14728,Q9HD20,P00846,Q9Y6M7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
382,5,133,529,14,143,157,538,547,48,305,560,307,430,56,314,186,571,311,586,70,327,204,335,591,458,604,86,221,220,473,348,349,469,600,353,101,231,109,111,235,366,244,121,390
|
2315,86,931,1528,2514,311,143,813,1140,1496,56,382,914,121,916,1533,949,1178,1704,2946,2151,1211,2923,1753,1274,469,664,762,1101,724,235,353,982,2104,5,547,2851,571,2326,666,307,430,839,1008,1841,458,14,1544,3204,204,1674,591,1067,1249,1185,600,2900,780,1721,2203,1550,560,366,1393,335,1015,799,3394,604,348,1814,538,1291,349,133,529,3256,327,186,1509,314,109,1975,473,964,231,1022,1735,803,1230,305,2965,968,70,1299,157,1201,1883,907,1406,244,101,3406,834,111,48,1339,586,1056,220,634,1031,221,3333,390
|
-0.43569894708233464,2.5425880302168293,0.24879026863223094,-0.09573868680970035,-0.5179207785497725,1.1685858128764244,1.9973622966526008,0.36038744680166185,0.11658683691935393,-0.07619722251063903,3.0567507737172264,0.999504346348033,0.2674983597767239,2.162978192726338,0.2674983597767239,-0.09573868680970035,0.23003816681518965,0.09751936170847361,-0.1743976571717926,-0.7487318629297377,-0.3543509374216771,0.0784057608191252,-0.7274549681465066,-0.19418721956236745,0.04003907639528579,0.8269144177911181,0.5249283688242936,0.41560864305026346,0.13560845959237622,0.4522133253996353,1.448448785568869,1.0675480922862204,0.2112417984925894,-0.3341478103334249,4.917492659435559,0.7039155427404739,-0.6850808626505676,0.6684312487998063,-0.43569894708233464,0.5249283688242936,1.1853076769616102,0.8963828986355812,0.34189565270391015,0.19240090545282404,-0.23391832955023042,0.8443364414586735,4.496083243944842,-0.09573868680970035,-1.0309922696079223,1.6088736896093438,-0.15465833406450158,0.6327920744221581,0.15458450029912923,0.05924575850806966,0.09751936170847361,0.6149138846414414,-0.7062381065178011,0.3972437030547652,-0.1743976571717926,-0.3746072665047304,-0.09573868680970035,0.6861926522306766,1.0335956619699211,-0.017863872838918923,1.1182193515975896,0.19240090545282404,0.37883671691997084,-1.8749638166066318,0.6149138846414414,1.0844726591413512,-0.21402733728023318,0.7216001253197305,0.04003907639528579,1.0844726591413512,2.10311335779798,0.7392466032253644,-1.0976844720755563,1.1350418152893942,1.7194151890935954,-0.07619722251063903,1.1685858128764244,2.3108961338926965,-0.27385423081555665,0.8269144177911181,0.23003816681518965,1.4807753146449134,0.19240090545282404,-0.1743976571717926,0.37883671691997084,0.0784057608191252,1.2019963358891592,-0.7487318629297377,0.23003816681518965,2.8655806296701516,0.04003907639528579,1.9056938106121482,0.09751936170847361,-0.23391832955023042,0.2861626937330696,-0.017863872838918923,1.4159992226041558,2.3839446526313073,-2.285109634377232,0.36038744680166185,2.2962144810512832,3.1642440468955613,0.020785433429236007,0.6506311257033517,0.17351522707522676,1.5290369140825837,0.5790392392161661,0.19240090545282404,1.5290369140825837,-1.3014824482535676,0.999504346348033
| 3,425
|
Organic anion transmembrane transporter activity
| 15
| 34
| 2.908239
| 0.003635
|
Q9UJS0,P33527,Q8TB61,Q9UBX3,Q9BQT8,P53985,P41440,Q14728,Q6NUK1,O00400,Q9Y619,P30825,Q9H2D1,Q9Y6M7,P12235
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
586,666,109,111,305,591,458,366,604,86,221,571,157,390,469
|
86,1528,2514,813,1140,949,2151,1274,469,664,571,666,458,1674,591,1550,366,1015,604,1814,3256,109,1022,1735,1230,305,157,1201,1883,1406,111,586,221,390
|
2.5425880302168293,-0.09573868680970035,-0.5179207785497725,0.36038744680166185,0.11658683691935393,0.23003816681518965,-0.3543509374216771,0.04003907639528579,0.8269144177911181,0.5249283688242936,0.6684312487998063,0.5249283688242936,0.8443364414586735,-0.15465833406450158,0.6327920744221581,-0.09573868680970035,1.0335956619699211,0.19240090545282404,0.6149138846414414,-0.21402733728023318,-1.0976844720755563,2.3108961338926965,0.19240090545282404,-0.1743976571717926,0.0784057608191252,1.2019963358891592,1.9056938106121482,0.09751936170847361,-0.23391832955023042,-0.017863872838918923,2.2962144810512832,0.6506311257033517,1.5290369140825837,0.999504346348033
| 3,425
|
EF-Hand 1, calcium-binding site [IPR018247]
| 12
| 37
| 2.892993
| 0.003816
|
O43852,Q9NWM8,O95202,P07384,Q14257,P80303,Q9BRK5,Q9Y680,Q02818,P41208,O95302,Q96AY3
|
Sequence
|
InterPro Binding site
|
interpro_binding_site
|
380,194,382,352,168,6,370,50,51,277,85,243
|
1237,380,2477,1140,382,85,352,1383,3288,2892,3275,2849,873,1754,277,1278,6,51,1677,2120,168,2928,2162,604,1862,2218,243,1328,1403,370,633,849,194,2840,1337,455,50
|
0.05924575850806966,0.999504346348033,-0.4972821326535668,0.11658683691935393,0.999504346348033,2.5568725955541236,1.0675480922862204,-0.017863872838918923,-1.1649875074107834,-0.7062381065178011,-1.142484440376989,-0.6850808626505676,0.304783521666528,-0.19418721956236745,1.2849471759441964,0.04003907639528579,4.895159421570552,3.137486998744578,-0.15465833406450158,-0.3341478103334249,1.8285620188685285,-0.7274549681465066,-0.3543509374216771,0.6149138846414414,-0.23391832955023042,-0.3746072665047304,1.4159992226041558,0.020785433429236007,-0.017863872838918923,1.0335956619699211,0.5790392392161661,0.34189565270391015,1.6879761304662688,-0.663982825714329,0.020785433429236007,0.8617217363584101,3.1508751318963872
| 3,425
|
Postural tremor
| 7
| 23
| 2.891636
| 0.003832
|
P00846,Q9NQ11,P03886,Q14108,O14773,Q9NR77,Q9H6K4
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
121,101,69,13,89,29,57
|
89,1891,173,555,913,2845,121,69,507,915,1797,495,1545,324,13,3240,2834,2875,57,1266,101,29,2724
|
2.5139509284160675,-0.25386051882213734,1.7975170034836079,0.6861926522306766,0.2674983597767239,-0.6850808626505676,2.162978192726338,2.8655806296701516,0.7744260494954054,0.2674983597767239,-0.21402733728023318,0.7919594158846363,-0.09573868680970035,1.1350418152893942,4.530920591223999,-1.075386542805351,-0.663982825714329,-0.6850808626505676,3.0432261828019507,0.05924575850806966,2.3839446526313073,3.59506153369759,-0.6010399151957811
| 3,425
|
Proton transmembrane transporter activity
| 14
| 39
| 2.88666
| 0.003894
|
P61421,O95202,P20674,Q96ES6,P24539,Q7KZN9,P51790,Q9UDW1,Q13423,O00400,O75964,P00846,Q93050,P12235
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
600,382,353,231,547,529,204,48,560,86,56,121,473,469
|
86,931,1496,56,382,914,121,949,1178,1211,1753,469,762,1101,353,982,2104,547,2851,2326,839,1008,1841,1544,3204,204,1249,1185,600,1721,560,529,473,231,1201,48,1339,634,1031
|
2.5425880302168293,0.24879026863223094,-0.07619722251063903,3.0567507737172264,0.999504346348033,0.2674983597767239,2.162978192726338,0.23003816681518965,0.09751936170847361,0.0784057608191252,-0.19418721956236745,0.8269144177911181,0.41560864305026346,0.13560845959237622,1.0675480922862204,0.2112417984925894,-0.3341478103334249,0.7039155427404739,-0.6850808626505676,-0.43569894708233464,0.34189565270391015,0.19240090545282404,-0.23391832955023042,-0.09573868680970035,-1.0309922696079223,1.6088736896093438,0.05924575850806966,0.09751936170847361,0.6149138846414414,-0.1743976571717926,0.6861926522306766,0.7392466032253644,0.8269144177911181,1.4807753146449134,0.09751936170847361,3.1642440468955613,0.020785433429236007,0.5790392392161661,0.19240090545282404
| 3,425
|
Sterol metabolic process
| 14
| 42
| 2.882613
| 0.003944
|
Q8WTV0,O75845,Q15125,Q15392,O15118,Q15800,P05067,Q16850,P04062,Q14534,Q9BQE5,Q14739,P16435,P34913
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,162,151,36,97,43,297,46,80,407,20,281,435,470
|
97,980,162,894,1898,3198,80,297,494,1038,435,3232,470,1540,1009,3289,2483,1500,2565,2066,1039,1218,2698,2927,2116,1250,2575,407,281,151,2346,36,1915,43,46,64,20,806,972,2468,2370,1088
|
2.3984830795821077,0.2112417984925894,1.844043079409893,0.2861626937330696,-0.25386051882213734,-1.0309922696079223,2.62795906725318,1.2186519515565648,0.7919594158846363,0.17351522707522676,0.8790704925764257,-1.075386542805351,0.8269144177911181,-0.09573868680970035,0.19240090545282404,-1.1649875074107834,-0.4972821326535668,-0.07619722251063903,-0.5386155010309926,-0.31399754246940065,0.17351522707522676,0.0784057608191252,-0.6010399151957811,-0.7274549681465066,-0.3341478103334249,0.05924575850806966,-0.5386155010309926,0.9481038780076505,1.268422139234549,1.9210387080998343,-0.43569894708233464,3.3886394720355844,-0.25386051882213734,3.2440577254623797,3.1775938115320623,2.920606361818982,4.007216364080601,0.37883671691997084,0.23003816681518965,-0.4766991906424338,-0.43569894708233464,0.15458450029912923
| 3,425
|
Sphingolipid biosynthetic process
| 9
| 19
| 2.8807
| 0.003968
|
Q9P035,Q96G23,O15269,P04062,Q13510,Q06136,O95470,P27544,Q9NRA0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
585,103,172,80,17,527,118,125,290
|
172,1095,118,80,2284,125,1912,527,1250,17,2662,1597,697,103,606,290,1822,585,2369
|
1.7975170034836079,0.13560845959237622,2.2224410858737813,2.62795906725318,-0.4152809195710186,2.133096436106864,-0.25386051882213734,0.7392466032253644,0.05924575850806966,4.3200361894985715,-0.5801746865595289,-0.11532915716857117,0.4886526246803302,2.3693825937809168,0.6149138846414414,1.2518646944415734,-0.21402733728023318,0.6506311257033517,-0.43569894708233464
| 3,425
|
Nuclear outer membrane endoplasmic reticulum membrane network
| 123
| 354
| 2.876648
| 0.004019
|
O00264,P50402,P24390,Q14108,Q99720,Q96KC8,Q06136,Q9BQE5,P30519,Q9Y282,Q9Y5P4,P30511,Q15392,P43307,Q4ZIN3,Q15800,Q16850,Q8NBI6,Q8N511,P07099,P20340,Q5BJF2,Q9P035,Q6NUK4,Q15005,Q86XL3,Q8IV08,Q6UWP7,Q15629,O75787,O00400,Q9UKV5,O60725,O95197,Q15363,Q9NZ01,Q15041,O15260,P09601,Q96G23,Q9BUR5,Q8TB61,Q9NZ08,Q8NHH9,O95470,P27544,Q9BS26,Q96RQ1,Q9H3N1,Q6IC98,Q9Y5M8,Q6UX53,P51648,Q9NUN5,Q9Y4P3,Q96AA3,Q9P2W9,Q15125,O75844,Q96GC9,Q9UKU0,O75845,Q99523,O15269,Q9BRR6,Q15904,Q96N66,Q9Y320,Q9UEU0,Q8NF37,Q8N4V1,Q86UE4,Q6Y1H2,P26885,Q9NQC3,Q86YN1,Q9UBU6,Q9GZP9,Q03519,Q9HD20,Q5BJH7,P56962,Q9Y3A6,Q6NUM9,P35613,Q9BZF1,Q10472,P67812,Q14739,Q9Y3B3,Q53GQ0,P49257,O14681,Q12907,Q9UBV2,P49755,Q6NUQ1,Q9BT22,Q8NAT1,Q9NP73,Q8N5M9,Q9UGP8,O43852,Q8N2F6,Q70UQ0,P10321,Q7Z2K6,Q14534,O75298,O95070,O00560,Q8IWB1,P49069,P36383,Q86Y07,Q96A33,P16435,Q9Y2B2,Q96PC5,Q8N2K0,O43292,Q07065,A1L0T0
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
514,517,12,13,15,531,527,20,21,24,544,28,36,40,41,43,46,562,53,58,570,65,585,581,579,78,79,592,84,590,86,610,88,90,93,94,601,99,102,103,621,109,113,632,118,125,645,129,646,642,135,655,141,145,679,152,153,151,154,676,158,162,686,172,175,177,178,707,706,700,186,698,697,692,210,212,219,227,236,244,247,249,253,256,254,261,270,269,281,284,299,323,332,334,337,343,354,361,368,376,387,389,380,393,392,396,398,407,403,413,419,434,431,430,439,441,435,456,462,489,480,484,505
|
1489,505,1991,514,86,1306,2513,419,1006,946,332,3343,1491,3261,1746,1033,739,776,99,172,1095,1893,480,812,777,380,814,1995,2684,88,1061,1456,403,2477,2417,980,590,154,162,2150,691,894,3181,1381,2975,1898,2418,2278,413,90,2845,118,2419,1245,2057,1422,1497,3294,3198,2804,1311,1532,2378,1097,3272,58,3077,1212,102,396,1460,435,724,1707,1952,570,2284,3184,12,692,125,3174,2246,3081,2951,28,21,873,2061,2327,1351,1540,254,430,1009,934,2331,1181,2108,40,1711,1905,1500,3392,743,431,323,1758,343,1671,517,1634,918,1247,141,819,1010,2519,2898,2811,3059,3217,249,877,2658,1011,1068,2020,3001,1636,1069,1804,3278,2900,3388,2157,2434,1719,1431,1071,1548,1910,269,2289,2253,1677,1640,236,3189,527,484,989,270,2024,334,3101,1110,1284,3102,2781,13,1254,2075,407,281,579,748,601,3032,151,93,36,781,84,1915,43,177,2077,46,1076,41,299,65,247,821,1438,1597,1259,2166,770,1191,642,882,581,256,354,2622,1078,1814,939,592,655,697,2495,392,398,1116,698,729,1726,78,439,212,79,434,1727,1475,393,489,186,53,1648,387,1771,924,368,562,717,700,2497,731,632,2083,3168,109,1973,1561,3109,2713,2084,1866,942,824,1730,1228,1048,2134,783,1924,1976,1079,441,152,2262,1398,103,676,1926,1734,1977,1161,531,178,462,1000,129,829,803,1514,686,927,15,903,3208,20,175,645,1931,361,2227,1083,621,2965,3410,2460,261,757,2937,227,1299,1777,1568,906,646,2588,2040,787,2674,1651,2142,244,1331,376,1372,210,1166,1026,145,2174,3406,806,3011,1822,94,113,585,3089,2369,2839,153,2232,1886,972,219,337,706,389,944,2370,1088,158,610,1268,1056,1133,1987,24,456,707,1698,253,284,3014,679,1660,135,544,1661,810,1205,1574,1452,975,1343
|
-0.07619722251063903,0.7744260494954054,-0.2938997945656019,0.7568551780007351,2.5425880302168293,0.020785433429236007,-0.5179207785497725,0.9136591415130947,0.19240090545282404,0.23003816681518965,1.1182193515975896,-1.3707038556261375,-0.07619722251063903,-1.1200502676254012,-0.19418721956236745,0.17351522707522676,0.4339317726253653,0.3972437030547652,2.3839446526313073,1.7975170034836079,0.13560845959237622,-0.25386051882213734,0.8094554736885617,0.36038744680166185,0.3972437030547652,0.999504346348033,0.36038744680166185,-0.2938997945656019,-0.6010399151957811,2.528280837326959,0.15458450029912923,-0.056704463496115395,0.9481038780076505,-0.4972821326535668,-0.4766991906424338,0.2112417984925894,0.6327920744221581,1.9056938106121482,1.844043079409893,-0.3543509374216771,0.4886526246803302,0.2861626937330696,-1.00889493373649,-0.017863872838918923,-0.7700692108929594,-0.25386051882213734,-0.4766991906424338,-0.4152809195710186,0.9308994066578831,2.5139509284160675,-0.6850808626505676,2.2224410858737813,-0.4766991906424338,0.05924575850806966,-0.31399754246940065,-0.03726011192253851,-0.07619722251063903,-1.1875599920679472,-1.0309922696079223,-0.663982825714329,0.020785433429236007,-0.09573868680970035,-0.4561715837491249,0.13560845959237622,-1.142484440376989,3.0161176060467145,-0.8560317012161593,0.0784057608191252,2.3693825937809168,0.9652727380057537,-0.056704463496115395,0.8790704925764257,0.4522133253996353,-0.1743976571717926,-0.27385423081555665,0.6684312487998063,-0.4152809195710186,-1.00889493373649,4.5656364088713355,0.4886526246803302,2.133096436106864,-0.9868634800659423,-0.39491714390968624,-0.8560317012161593,-0.7487318629297377,3.6205514552672318,3.921251120524279,0.304783521666528,-0.31399754246940065,-0.43569894708233464,0.001484545851543285,-0.09573868680970035,1.3507263392996962,0.8963828986355812,0.19240090545282404,0.24879026863223094,-0.43569894708233464,0.09751936170847361,-0.3341478103334249,3.296890926305054,-0.1743976571717926,-0.25386051882213734,-0.07619722251063903,-1.8501181590001228,0.4339317726253653,0.8963828986355812,1.1350418152893942,-0.19418721956236745,1.10136302234031,-0.15465833406450158,0.7568551780007351,-0.13496893733397167,0.2674983597767239,0.05924575850806966,2.027706771884764,0.36038744680166185,0.19240090545282404,-0.5179207785497725,-0.7062381065178011,-0.663982825714329,-0.8344482451084184,-1.0531559749508097,1.3834254662027163,0.304783521666528,-0.5801746865595289,0.19240090545282404,0.15458450029912923,-0.2938997945656019,-0.79146743676524,-0.13496893733397167,0.15458450029912923,-0.21402733728023318,-1.142484440376989,-0.7062381065178011,-1.8006896901206986,-0.3543509374216771,-0.4766991906424338,-0.1743976571717926,-0.03726011192253851,0.15458450029912923,-0.09573868680970035,-0.25386051882213734,1.3014399603266282,-0.4152809195710186,-0.39491714390968624,-0.15465833406450158,-0.13496893733397167,1.448448785568869,-1.00889493373649,0.7392466032253644,0.8094554736885617,0.2112417984925894,1.3014399603266282,-0.2938997945656019,1.1182193515975896,-0.8776777826591424,0.13560845959237622,0.04003907639528579,-0.8776777826591424,-0.6429435893726733,4.530920591223999,0.05924575850806966,-0.31399754246940065,0.9481038780076505,1.268422139234549,0.6506311257033517,0.4339317726253653,0.6149138846414414,-0.8129269700518783,1.9210387080998343,2.4564023437522535,3.3886394720355844,0.3972437030547652,2.599591402744298,-0.25386051882213734,3.2440577254623797,1.7819528049746483,-0.31399754246940065,3.1775938115320623,0.15458450029912923,3.2705115690490496,1.2186519515565648,2.9068807648891117,1.3997279417347968,0.36038744680166185,-0.03726011192253851,-0.11532915716857117,0.05924575850806966,-0.3543509374216771,0.41560864305026346,0.09751936170847361,0.5610423537706956,0.304783521666528,0.6506311257033517,1.3507263392996962,1.0675480922862204,-0.5593666767876478,0.15458450029912923,-0.21402733728023318,0.24879026863223094,0.6327920744221581,0.5430054701796704,0.4886526246803302,-0.4972821326535668,0.9824061676177961,0.9652727380057537,0.13560845959237622,0.4886526246803302,0.4522133253996353,-0.1743976571717926,2.6703449638891956,0.8790704925764257,1.5450638238651857,2.6703449638891956,0.8963828986355812,-0.1743976571717926,-0.056704463496115395,0.9824061676177961,0.8094554736885617,1.7194151890935954,3.1106528049037374,-0.13496893733397167,0.999504346348033,-0.19418721956236745,0.2674983597767239,1.0335956619699211,0.6861926522306766,0.4704535329188798,0.4886526246803302,-0.4972821326535668,0.4522133253996353,0.5790392392161661,-0.31399754246940065,-0.9648974270030561,2.3108961338926965,-0.27385423081555665,-0.09573868680970035,-0.8776777826591424,-0.6010399151957811,-0.31399754246940065,-0.23391832955023042,0.24879026863223094,0.36038744680166185,-0.1743976571717926,0.0784057608191252,0.17351522707522676,-0.3341478103334249,0.3972437030547652,-0.25386051882213734,-0.27385423081555665,0.15458450029912923,0.8790704925764257,1.9210387080998343,-0.39491714390968624,-0.017863872838918923,2.3693825937809168,0.5249283688242936,-0.25386051882213734,-0.1743976571717926,-0.27385423081555665,0.11658683691935393,0.7392466032253644,1.7819528049746483,0.8443364414586735,0.2112417984925894,2.118117615036976,0.36038744680166185,0.37883671691997084,-0.07619722251063903,0.5068108281574367,0.2674983597767239,4.355497276975648,0.2861626937330696,-1.0309922696079223,4.007216364080601,1.7975170034836079,0.5610423537706956,-0.25386051882213734,1.0505891507074792,-0.3746072665047304,0.15458450029912923,0.5969963442295187,-0.7487318629297377,-2.8067413301893493,-0.4766991906424338,1.3343293891978911,0.4339317726253653,-0.7274549681465066,1.4968927991314636,0.04003907639528579,-0.19418721956236745,-0.09573868680970035,0.2861626937330696,0.5610423537706956,-0.5386155010309926,-0.2938997945656019,0.3972437030547652,-0.5801746865595289,-0.13496893733397167,-0.3341478103334249,1.4159992226041558,0.020785433429236007,1.0165674522554908,0.001484545851543285,1.5610608196920086,0.11658683691935393,0.19240090545282404,1.9973622966526008,-0.3543509374216771,-2.285109634377232,0.37883671691997084,-0.79146743676524,-0.21402733728023318,2.4564023437522535,2.281508618182512,0.6506311257033517,-0.8560317012161593,-0.43569894708233464,-0.663982825714329,1.9210387080998343,-0.3746072665047304,-0.23391832955023042,0.23003816681518965,1.5290369140825837,1.1182193515975896,0.4886526246803302,0.999504346348033,0.24879026863223094,-0.43569894708233464,0.15458450029912923,1.8903219166647762,0.6149138846414414,0.05924575850806966,0.17351522707522676,0.13560845959237622,-0.27385423081555665,3.709233648956977,0.8617217363584101,0.4886526246803302,-0.15465833406450158,1.3670916483246272,1.268422139234549,-0.79146743676524,0.5249283688242936,-0.13496893733397167,2.10311335779798,0.7216001253197305,-0.13496893733397167,0.37883671691997084,0.09751936170847361,-0.09573868680970035,-0.03726011192253851,0.23003816681518965,0.020785433429236007
| 3,425
|
Macromolecule transmembrane transporter activity
| 7
| 13
| 2.874446
| 0.004047
|
Q99595,O60830,Q9Y584,Q9NS69,P49755,O14925,Q9UGP8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
1,2,44,18,343,340,389
|
340,2,1380,1457,343,764,2900,798,416,1,18,389,44
|
1.10136302234031,5.203448495367863,-0.017863872838918923,-0.056704463496115395,1.10136302234031,0.41560864305026346,-0.7062381065178011,0.37883671691997084,0.9308994066578831,5.246740467606561,4.212879893636516,0.999504346348033,3.2440577254623797
| 3,425
|
Copii coated er to golgi transport vesicle
| 13
| 40
| 2.870051
| 0.004104
|
Q96RQ1,P49257,P10321,P05067,Q12907,P49755,Q9Y3B3,Q5BJH7,Q9Y282,P56962,P30511,Q15363,Q9Y3A6
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
129,323,396,297,334,343,284,247,24,249,28,93,253
|
739,1238,2477,2417,3181,2278,413,2419,1245,2804,1311,297,396,28,323,343,876,2811,3217,249,2340,334,1284,93,781,247,2125,1116,1079,129,2460,1568,789,1337,706,24,253,284,1661,1701
|
0.4339317726253653,0.05924575850806966,-0.4972821326535668,-0.4766991906424338,-1.00889493373649,-0.4152809195710186,0.9308994066578831,-0.4766991906424338,0.05924575850806966,-0.663982825714329,0.020785433429236007,1.2186519515565648,0.9652727380057537,3.6205514552672318,1.1350418152893942,1.10136302234031,0.304783521666528,-0.663982825714329,-1.0531559749508097,1.3834254662027163,-0.43569894708233464,1.1182193515975896,0.04003907639528579,2.4564023437522535,0.3972437030547652,1.3997279417347968,-0.3341478103334249,0.13560845959237622,0.15458450029912923,2.118117615036976,-0.4766991906424338,-0.09573868680970035,0.3972437030547652,0.020785433429236007,0.4886526246803302,3.709233648956977,1.3670916483246272,1.268422139234549,-0.13496893733397167,-0.15465833406450158
| 3,425
|
Organic anion transport
| 22
| 49
| 2.865942
| 0.004158
|
Q9Y5P4,O60831,Q9H2D1,P33527,Q9NZJ7,Q9BQT8,P30825,Q9UJS0,P07602,P14174,P53985,P41440,Q6NUK1,O00400,Q9Y619,Q15041,P12235,Q8TB61,Q9UBX3,Q14728,Q08722,Q9Y6M7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
544,402,157,666,552,305,571,586,77,333,591,458,604,86,221,601,469,109,111,366,628,390
|
86,1528,2514,813,402,1140,2150,778,949,2320,77,2151,1274,469,664,333,871,571,666,458,1674,591,1067,1550,628,1250,366,601,1015,604,1814,3256,109,1022,1735,1230,305,157,1201,1883,1406,736,552,111,2370,586,544,221,390
|
2.5425880302168293,-0.09573868680970035,-0.5179207785497725,0.36038744680166185,0.9481038780076505,0.11658683691935393,-0.3543509374216771,0.3972437030547652,0.23003816681518965,-0.43569894708233464,2.7125341584739417,-0.3543509374216771,0.04003907639528579,0.8269144177911181,0.5249283688242936,1.1182193515975896,0.304783521666528,0.6684312487998063,0.5249283688242936,0.8443364414586735,-0.15465833406450158,0.6327920744221581,0.15458450029912923,-0.09573868680970035,0.5790392392161661,0.05924575850806966,1.0335956619699211,0.6149138846414414,0.19240090545282404,0.6149138846414414,-0.21402733728023318,-1.0976844720755563,2.3108961338926965,0.19240090545282404,-0.1743976571717926,0.0784057608191252,1.2019963358891592,1.9056938106121482,0.09751936170847361,-0.23391832955023042,-0.017863872838918923,0.4522133253996353,0.7039155427404739,2.2962144810512832,-0.43569894708233464,0.6506311257033517,0.7216001253197305,1.5290369140825837,0.999504346348033
| 3,425
|
Endomembrane system organization
| 70
| 188
| 2.860741
| 0.004227
|
P48729,O43752,O94901,P50402,Q9ULX6,Q14108,Q96ED9,Q9H5V9,O15155,P31751,Q9H6H4,Q2M389,Q8N1F7,Q92783,Q9P2W9,Q9Y5P4,Q96GC9,O75844,Q9Y3B3,Q9UL15,Q4KMQ2,O95721,Q9BSR8,P49069,Q9UEU0,O95295,Q8TBA6,Q96A33,Q9HD42,Q8N4V1,Q5J8M3,O43681,O43402,P46379,P31749,Q6NUK4,Q9Y3E7,Q8IYI6,P49257,Q9BTU6,P51790,Q9H4A6,Q86XL3,Q12907,Q9UQB8,Q9NQC3,Q15629,Q8NFQ8,P49755,P41440,O95197,Q15363,Q15041,P16615,Q96CP7,P40616,O15260,P27361,Q7Z3D4,O43760,Q9Y5X1,Q15006,O15027,Q99816,Q8NHH9,Q12768,P50570,P56962,Q8N5M9,Q9Y3A6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
255,379,263,517,658,13,274,786,776,653,787,397,279,280,153,544,676,154,284,808,799,663,301,431,706,556,701,441,573,186,821,311,812,63,693,581,722,326,323,847,204,596,78,334,82,210,84,731,343,458,90,93,601,724,98,856,99,855,355,481,372,748,739,501,632,498,745,249,387,253
|
1489,2885,3157,1306,2600,977,1344,1528,1942,739,776,99,1893,812,1420,311,379,481,1994,1575,1238,1946,2417,1240,1242,154,853,263,2278,90,2845,556,663,1901,1097,2946,724,1313,2558,1797,2284,855,2194,693,653,2107,856,2733,458,2734,63,1588,255,431,323,343,517,745,2610,204,1317,1106,249,877,2020,1636,1430,1069,2900,1108,1357,2737,898,1964,1219,1912,2340,498,2957,334,1505,1110,2820,1284,13,958,1111,2343,748,601,2534,1810,93,84,397,799,821,1438,1769,961,581,2355,1725,355,1159,2665,1116,78,326,279,1972,186,387,1771,1605,996,2497,731,632,3168,701,1562,1198,1867,3240,2358,1974,280,441,98,274,676,1734,501,3292,3040,1404,1931,301,847,1690,2460,2937,1568,1479,906,596,786,787,1024,2674,1371,1447,573,1331,1372,210,2046,3406,1822,2270,3089,2369,3353,1783,153,706,1004,1087,2049,808,2941,658,1167,2412,2640,82,1168,1234,2413,1235,1657,253,284,722,544,372,1701
|
-0.07619722251063903,-0.7062381065178011,-0.9648974270030561,0.020785433429236007,-0.5593666767876478,0.2112417984925894,0.001484545851543285,-0.09573868680970035,-0.27385423081555665,0.4339317726253653,0.3972437030547652,2.3839446526313073,-0.25386051882213734,0.36038744680166185,-0.03726011192253851,1.1685858128764244,0.999504346348033,0.8094554736885617,-0.2938997945656019,-0.11532915716857117,0.05924575850806966,-0.27385423081555665,-0.4766991906424338,0.05924575850806966,0.05924575850806966,1.9056938106121482,0.32336109245226435,1.3179006469481906,-0.4152809195710186,2.5139509284160675,-0.6850808626505676,0.6861926522306766,0.5249283688242936,-0.25386051882213734,0.13560845959237622,-0.7487318629297377,0.4522133253996353,0.020785433429236007,-0.5386155010309926,-0.21402733728023318,-0.4152809195710186,0.32336109245226435,-0.3746072665047304,0.4886526246803302,0.5430054701796704,-0.3341478103334249,0.32336109245226435,-0.6219627517160322,0.8443364414586735,-0.6219627517160322,2.947996335155421,-0.11532915716857117,1.3507263392996962,0.8963828986355812,1.1350418152893942,1.10136302234031,0.7568551780007351,0.4339317726253653,-0.5593666767876478,1.6088736896093438,0.020785433429236007,0.13560845959237622,1.3834254662027163,0.304783521666528,-0.2938997945656019,-0.13496893733397167,-0.03726011192253851,0.15458450029912923,-0.7062381065178011,0.13560845959237622,0.001484545851543285,-0.6219627517160322,0.2861626937330696,-0.27385423081555665,0.0784057608191252,-0.25386051882213734,-0.43569894708233464,0.7919594158846363,-0.7487318629297377,1.1182193515975896,-0.07619722251063903,0.13560845959237622,-0.663982825714329,0.04003907639528579,4.530920591223999,0.23003816681518965,0.13560845959237622,-0.43569894708233464,0.4339317726253653,0.6149138846414414,-0.5179207785497725,-0.21402733728023318,2.4564023437522535,2.599591402744298,0.9652727380057537,0.37883671691997084,0.36038744680166185,-0.03726011192253851,-0.19418721956236745,0.23003816681518965,0.6506311257033517,-0.43569894708233464,-0.1743976571717926,1.0675480922862204,0.11658683691935393,-0.5801746865595289,0.13560845959237622,2.6703449638891956,1.1350418152893942,1.2849471759441964,-0.27385423081555665,1.7194151890935954,0.999504346348033,-0.19418721956236745,-0.11532915716857117,0.2112417984925894,-0.4972821326535668,0.4522133253996353,0.5790392392161661,-0.9648974270030561,0.4886526246803302,-0.09573868680970035,0.09751936170847361,-0.23391832955023042,-1.075386542805351,-0.43569894708233464,-0.27385423081555665,1.2849471759441964,0.8790704925764257,2.3984830795821077,1.3014399603266282,0.5249283688242936,-0.1743976571717926,0.7919594158846363,-1.1649875074107834,-0.8129269700518783,-0.017863872838918923,-0.25386051882213734,1.2186519515565648,0.34189565270391015,-0.15465833406450158,-0.4766991906424338,-0.7274549681465066,-0.09573868680970035,-0.056704463496115395,0.2861626937330696,0.6327920744221581,0.3972437030547652,0.3972437030547652,0.19240090545282404,-0.5801746865595289,0.001484545851543285,-0.03726011192253851,0.6684312487998063,0.020785433429236007,0.001484545851543285,1.5610608196920086,-0.2938997945656019,-2.285109634377232,-0.21402733728023318,-0.39491714390968624,-0.8560317012161593,-0.43569894708233464,-1.4172226355338577,-0.19418721956236745,1.9210387080998343,0.4886526246803302,0.2112417984925894,0.15458450029912923,-0.2938997945656019,0.37883671691997084,-0.7274549681465066,0.5430054701796704,0.11658683691935393,-0.4561715837491249,-0.5593666767876478,2.62795906725318,0.11658683691935393,0.0784057608191252,-0.4561715837491249,0.0784057608191252,-0.13496893733397167,1.3670916483246272,1.268422139234549,0.4704535329188798,0.7216001253197305,1.0335956619699211,-0.15465833406450158
| 3,425
|
Protein transmembrane transporter activity
| 7
| 12
| 2.849442
| 0.00438
|
Q99595,O60830,Q9Y584,Q9NS69,P49755,O14925,Q9UGP8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
1,2,44,18,343,340,389
|
340,2,1380,1457,343,2900,798,416,1,18,389,44
|
1.10136302234031,5.203448495367863,-0.017863872838918923,-0.056704463496115395,1.10136302234031,-0.7062381065178011,0.37883671691997084,0.9308994066578831,5.246740467606561,4.212879893636516,0.999504346348033,3.2440577254623797
| 3,425
|
Glycosidase
| 8
| 18
| 2.84066
| 0.004502
|
P54802,P06280,P16278,O60476,P04062,O60502,Q9BTY2,P06865
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
202,139,10,302,80,267,214,384
|
2761,1060,302,267,80,576,139,384,1750,421,10,1668,202,1503,2781,2621,1016,214
|
-0.6429435893726733,0.15458450029912923,1.2019963358891592,1.3014399603266282,2.62795906725318,0.6506311257033517,2.057946899190213,0.999504346348033,-0.19418721956236745,0.9136591415130947,4.600231735570217,-0.15465833406450158,1.6247523908291193,-0.07619722251063903,-0.6429435893726733,-0.5593666767876478,0.19240090545282404,1.5450638238651857
| 3,425
|
Secondary active transmembrane transporter activity
| 10
| 22
| 2.840251
| 0.004508
|
O95202,Q96ES6,P51790,Q15043,Q9UBX3,P53985,P41440,O00400,Q9Y6M7,P12235
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
382,231,204,335,111,591,458,86,390,469
|
86,382,949,2151,469,664,458,204,1674,591,1067,1721,1550,335,1015,1509,231,1735,968,1201,111,390
|
2.5425880302168293,0.999504346348033,0.23003816681518965,-0.3543509374216771,0.8269144177911181,0.5249283688242936,0.8443364414586735,1.6088736896093438,-0.15465833406450158,0.6327920744221581,0.15458450029912923,-0.1743976571717926,-0.09573868680970035,1.1182193515975896,0.19240090545282404,-0.07619722251063903,1.4807753146449134,-0.1743976571717926,0.23003816681518965,0.09751936170847361,2.2962144810512832,0.999504346348033
| 3,425
|
Active ion transmembrane transporter activity
| 20
| 47
| 2.839673
| 0.004516
|
O95202,P13073,Q7KZN9,P33527,P12236,Q9UDW1,P35670,P51790,Q15043,P41440,O00400,P16615,P61421,P12235,P20674,Q9NQ11,Q96ES6,P20020,Q9HD20,Q9Y6M7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
382,762,529,666,664,48,307,204,335,458,86,724,600,469,353,101,231,235,244,390
|
86,931,2514,382,914,916,1533,949,1178,2151,1211,1753,469,664,762,1101,724,235,353,982,2104,2326,666,307,1008,1841,458,1544,204,1674,1067,600,780,1721,1550,335,529,231,1735,968,1201,244,101,48,1339,1031,390
|
2.5425880302168293,0.24879026863223094,-0.5179207785497725,0.999504346348033,0.2674983597767239,0.2674983597767239,-0.09573868680970035,0.23003816681518965,0.09751936170847361,-0.3543509374216771,0.0784057608191252,-0.19418721956236745,0.8269144177911181,0.5249283688242936,0.41560864305026346,0.13560845959237622,0.4522133253996353,1.448448785568869,1.0675480922862204,0.2112417984925894,-0.3341478103334249,-0.43569894708233464,0.5249283688242936,1.1853076769616102,0.19240090545282404,-0.23391832955023042,0.8443364414586735,-0.09573868680970035,1.6088736896093438,-0.15465833406450158,0.15458450029912923,0.6149138846414414,0.3972437030547652,-0.1743976571717926,-0.09573868680970035,1.1182193515975896,0.7392466032253644,1.4807753146449134,-0.1743976571717926,0.23003816681518965,0.09751936170847361,1.4159992226041558,2.3839446526313073,3.1642440468955613,0.020785433429236007,0.19240090545282404,0.999504346348033
| 3,425
|
Anion transmembrane transporter activity
| 22
| 49
| 2.836246
| 0.004565
|
P21796,P45880,Q9H2D1,P33527,Q9BQT8,P30825,O43681,Q9UJS0,Q9C0H2,P51790,Q15043,P53985,P41440,Q6NUK1,O00400,Q9Y619,Q9Y277,P12235,Q8TB61,Q9UBX3,Q14728,Q9Y6M7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
5,14,157,666,305,571,311,586,70,204,335,591,458,604,86,221,220,469,109,111,366,390
|
2315,86,1528,2514,311,813,1140,949,2151,2923,1274,469,664,5,571,666,458,14,204,1674,591,1067,1550,366,335,1015,799,3394,604,1814,3256,109,1022,1735,803,1230,305,968,70,157,1201,1883,1406,111,586,220,221,3333,390
|
-0.43569894708233464,2.5425880302168293,-0.09573868680970035,-0.5179207785497725,1.1685858128764244,0.36038744680166185,0.11658683691935393,0.23003816681518965,-0.3543509374216771,-0.7274549681465066,0.04003907639528579,0.8269144177911181,0.5249283688242936,4.917492659435559,0.6684312487998063,0.5249283688242936,0.8443364414586735,4.496083243944842,1.6088736896093438,-0.15465833406450158,0.6327920744221581,0.15458450029912923,-0.09573868680970035,1.0335956619699211,1.1182193515975896,0.19240090545282404,0.37883671691997084,-1.8749638166066318,0.6149138846414414,-0.21402733728023318,-1.0976844720755563,2.3108961338926965,0.19240090545282404,-0.1743976571717926,0.37883671691997084,0.0784057608191252,1.2019963358891592,0.23003816681518965,2.8655806296701516,1.9056938106121482,0.09751936170847361,-0.23391832955023042,-0.017863872838918923,2.2962144810512832,0.6506311257033517,1.5290369140825837,1.5290369140825837,-1.3014824482535676,0.999504346348033
| 3,425
|
Subsets and Splits
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