term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Biliary tract abnormality
| 14
| 26
| 2.827883
| 0.004686
|
O96028,O95202,Q9NZJ7,Q13043,P09601,Q9UJW0,Q5XKP0,Q14108,P07602,P14174,P04062,Q9NUN5,Q14739,O43681
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
131,382,552,550,102,266,561,13,77,333,80,145,281,311
|
311,382,131,1901,80,77,102,333,3377,3054,1587,2198,727,550,2958,13,281,561,2085,826,565,145,552,266,1888,1660
|
1.1685858128764244,0.999504346348033,2.10311335779798,-0.25386051882213734,2.62795906725318,2.7125341584739417,2.3693825937809168,1.1182193515975896,-1.6303721469296955,-0.8344482451084184,-0.11532915716857117,-0.3746072665047304,0.4522133253996353,0.7039155427404739,-0.7487318629297377,4.530920591223999,1.268422139234549,0.6861926522306766,-0.31399754246940065,0.36038744680166185,0.6861926522306766,1.9973622966526008,0.7039155427404739,1.3179006469481906,-0.23391832955023042,-0.13496893733397167
| 3,425
|
Cholesterol metabolism with bloch and kandutschrussell pathways
| 7
| 25
| 2.827058
| 0.004698
|
O75845,Q15125,Q15392,Q15800,Q16850,Q14739,Q9BWD1
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
162,151,36,43,46,281,27
|
1006,1995,162,894,2057,1497,1038,2327,1540,1009,1500,526,2927,2116,2575,407,281,151,2346,36,1915,43,46,27,972
|
0.19240090545282404,-0.2938997945656019,1.844043079409893,0.2861626937330696,-0.31399754246940065,-0.07619722251063903,0.17351522707522676,-0.43569894708233464,-0.09573868680970035,0.19240090545282404,-0.07619722251063903,0.7392466032253644,-0.7274549681465066,-0.3341478103334249,-0.5386155010309926,0.9481038780076505,1.268422139234549,1.9210387080998343,-0.43569894708233464,3.3886394720355844,-0.25386051882213734,3.2440577254623797,3.1775938115320623,3.633270890999699,0.23003816681518965
| 3,425
|
Tetrapyrrole binding
| 10
| 17
| 2.825979
| 0.004714
|
O15173,P09601,O00264,Q8WUJ1,Q16850,Q6UW02,Q9NUN5,P30519,Q9H7Z7,O43169
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
229,102,514,110,46,336,145,21,478,31
|
514,229,31,1211,102,3130,21,919,46,336,529,110,1080,830,478,3269,145
|
0.7568551780007351,1.4807753146449134,3.4795033148248145,0.0784057608191252,2.3693825937809168,-0.9211596241735596,3.921251120524279,0.2674983597767239,3.1775938115320623,1.1182193515975896,0.7392466032253644,2.3108961338926965,0.15458450029912923,0.36038744680166185,0.8269144177911181,-1.1200502676254012,1.9973622966526008
| 3,425
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 11
| 31
| 2.816159
| 0.00486
|
Q8NB78,O75845,P09601,Q15800,Q16850,Q6UW02,Q14534,P30519,Q32P28,P13674,Q9BU89
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
32,162,102,43,46,336,407,21,119,222,224
|
2513,1006,662,2973,2684,162,1497,613,102,222,435,1799,21,797,2253,2024,407,43,46,119,537,1815,1223,336,3067,32,224,2936,2720,930,2273
|
-0.5179207785497725,0.19240090545282404,0.5249283688242936,-0.7700692108929594,-0.6010399151957811,1.844043079409893,-0.07619722251063903,0.5969963442295187,2.3693825937809168,1.5129799522193979,0.8790704925764257,-0.21402733728023318,3.921251120524279,0.37883671691997084,-0.39491714390968624,-0.2938997945656019,0.9481038780076505,3.2440577254623797,3.1775938115320623,2.2224410858737813,0.7216001253197305,-0.21402733728023318,0.0784057608191252,1.1182193515975896,-0.8344482451084184,3.4276882240821887,1.5129799522193979,-0.7274549681465066,-0.6010399151957811,0.2674983597767239,-0.39491714390968624
| 3,425
|
Liposaccharide metabolic process
| 9
| 20
| 2.812208
| 0.00492
|
P17900,O43292,P04066,P16278,P06280,P04062,Q8NBX0,P06865,Q9Y2B2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
166,480,576,10,139,80,122,384,456
|
480,1061,80,576,139,384,1750,10,166,1912,1250,122,1048,1924,829,606,2588,806,736,456
|
0.8094554736885617,0.15458450029912923,2.62795906725318,0.6506311257033517,2.057946899190213,0.999504346348033,-0.19418721956236745,4.600231735570217,1.8285620188685285,-0.25386051882213734,0.05924575850806966,2.162978192726338,0.17351522707522676,-0.25386051882213734,0.36038744680166185,0.6149138846414414,-0.5386155010309926,0.37883671691997084,0.4522133253996353,0.8617217363584101
| 3,425
|
Serine hydrolase activity
| 10
| 21
| 2.802198
| 0.005076
|
P42785,O75976,Q16740,Q9H3G5,P67812,Q5JRX3,P10619,Q2T9J0,O14773,Q9HB40
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
37,516,74,106,269,460,114,308,89,30
|
89,777,516,114,2153,3131,1587,37,817,1635,876,269,74,308,580,460,882,3068,1123,106,30
|
2.5139509284160675,0.3972437030547652,0.7568551780007351,2.2667784467407786,-0.3543509374216771,-0.9211596241735596,-0.11532915716857117,3.3755871954184276,0.36038744680166185,-0.13496893733397167,0.304783521666528,1.3014399603266282,2.7963313322340135,1.1853076769616102,0.6506311257033517,0.8443364414586735,0.304783521666528,-0.8344482451084184,0.13560845959237622,2.340187200505293,3.5053048346626823
| 3,425
|
Nephrotic syndrome
| 9
| 30
| 2.792594
| 0.005229
|
Q9BT22,P06280,Q14108,Q96AX1,P00813,Q8N1F7,O95470,P57740,Q8NCH0
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
361,139,13,209,180,279,118,436,123
|
118,663,180,139,2647,819,936,2774,436,1504,1912,1147,1149,1435,13,1325,1295,2932,279,123,2498,1261,209,491,361,966,1445,1407,2791,1742
|
2.2224410858737813,0.5249283688242936,1.7663606487132952,2.057946899190213,-0.5801746865595289,0.36038744680166185,0.24879026863223094,-0.6429435893726733,0.8790704925764257,-0.07619722251063903,-0.25386051882213734,0.11658683691935393,0.11658683691935393,-0.03726011192253851,4.530920591223999,0.020785433429236007,0.04003907639528579,-0.7274549681465066,1.2849471759441964,2.162978192726338,-0.4972821326535668,0.05924575850806966,1.5610608196920086,0.8094554736885617,1.0505891507074792,0.23003816681518965,-0.03726011192253851,-0.017863872838918923,-0.6429435893726733,-0.1743976571717926
| 3,425
|
Disproportionate short limb short stature
| 10
| 22
| 2.792122
| 0.005236
|
Q9Y366,Q15125,P10644,Q15392,O00116,Q6DKJ4,Q03164,Q32P28,Q14739,Q7LGA3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
321,151,163,36,199,367,211,119,281,350
|
199,2238,3145,412,163,2893,1181,1905,211,614,1188,281,151,36,119,367,350,996,942,3127,972,321
|
1.6564222106812256,-0.39491714390968624,-0.9429962985415629,0.9308994066578831,1.844043079409893,-0.7062381065178011,0.09751936170847361,-0.25386051882213734,1.5450638238651857,0.5969963442295187,0.09751936170847361,1.268422139234549,1.9210387080998343,3.3886394720355844,2.2224410858737813,1.0335956619699211,1.0844726591413512,0.2112417984925894,0.24879026863223094,-0.8993869388026995,0.23003816681518965,1.1518305804680873
| 3,425
|
Inorganic anion transport
| 11
| 27
| 2.787747
| 0.005308
|
Q9UHG3,Q9C0H2,P21796,P08183,P51790,P45880,Q15043,Q9UBX3,P30536,Q9Y277,O43681
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,70,5,322,204,14,335,111,242,220,311
|
2315,2514,311,322,2923,5,242,666,14,204,2199,1067,1721,1550,335,799,3394,3256,803,968,70,464,111,4,220,3333,390
|
-0.43569894708233464,-0.5179207785497725,1.1685858128764244,1.1350418152893942,-0.7274549681465066,4.917492659435559,1.4159992226041558,0.5249283688242936,4.496083243944842,1.6088736896093438,-0.3746072665047304,0.15458450029912923,-0.1743976571717926,-0.09573868680970035,1.1182193515975896,0.37883671691997084,-1.8749638166066318,-1.0976844720755563,0.37883671691997084,0.23003816681518965,2.8655806296701516,0.8443364414586735,2.2962144810512832,5.094411977540183,1.5290369140825837,-1.3014824482535676,0.999504346348033
| 3,425
|
Sterol metabolism
| 7
| 29
| 2.780943
| 0.00542
|
O75845,O15118,Q15392,Q15800,Q16850,P04062,Q15125
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
162,97,36,43,46,80,151
|
97,980,162,894,1898,3198,80,1038,3232,1540,1009,1039,1218,2698,2927,2116,1250,2575,281,151,2346,36,1915,43,46,972,2468,2370,1088
|
2.3984830795821077,0.2112417984925894,1.844043079409893,0.2861626937330696,-0.25386051882213734,-1.0309922696079223,2.62795906725318,0.17351522707522676,-1.075386542805351,-0.09573868680970035,0.19240090545282404,0.17351522707522676,0.0784057608191252,-0.6010399151957811,-0.7274549681465066,-0.3341478103334249,0.05924575850806966,-0.5386155010309926,1.268422139234549,1.9210387080998343,-0.43569894708233464,3.3886394720355844,-0.25386051882213734,3.2440577254623797,3.1775938115320623,0.23003816681518965,-0.4766991906424338,-0.43569894708233464,0.15458450029912923
| 3,425
|
Receptor
| 12
| 32
| 2.765963
| 0.005675
|
Q8WTV0,Q9GZP9,P57105,Q567V2,Q9Y639,A6NIH7,Q14108,P20645,Q9UQB8,Q6NYC1,Q9NR77,Q9HAV4
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
64,227,483,75,364,296,13,457,82,537,29,319
|
296,1033,2645,1577,590,1579,2764,2320,682,457,2653,483,2025,13,1808,2929,75,882,537,2495,64,1562,1083,227,319,1613,29,2092,1985,2271,82,364
|
1.2186519515565648,0.17351522707522676,-0.5801746865595289,-0.11532915716857117,0.6327920744221581,-0.11532915716857117,-0.6429435893726733,-0.43569894708233464,0.5068108281574367,0.8443364414586735,-0.5801746865595289,0.8094554736885617,-0.2938997945656019,4.530920591223999,-0.21402733728023318,-0.7274549681465066,2.7963313322340135,0.304783521666528,0.7216001253197305,-0.4972821326535668,2.920606361818982,-0.09573868680970035,0.15458450029912923,1.4968927991314636,1.1518305804680873,-0.11532915716857117,3.59506153369759,-0.31399754246940065,-0.27385423081555665,-0.39491714390968624,2.62795906725318,1.0505891507074792
| 3,425
|
Protein localization
| 29
| 83
| 2.762773
| 0.005731
|
Q99595,O60830,P21796,P50402,P51648,Q9NS69,Q9Y5J9,Q8N4H5,Q15388,Q9NR77,Q9NRP2,P40855,Q9Y584,P05067,O14734,P49069,Q2T9J0,O43681,Q9Y5J7,P46379,Q9NX63,O00116,Q13505,Q5JRX3,O14925,P34913,P12235,P09601,Q15067
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
1,2,5,517,141,18,411,150,416,29,295,422,44,297,176,431,308,311,188,63,195,199,73,460,340,470,469,102,386
|
199,176,340,1746,2238,524,740,311,1994,813,2,1577,3293,1172,2890,3338,1140,1379,1380,1382,1457,1900,297,1178,1211,3324,102,3182,469,664,2003,5,2004,2851,871,470,3201,3249,422,63,431,517,141,2198,920,2658,727,3030,1284,73,386,416,308,959,460,991,2355,150,1440,1361,1362,2085,825,1,3257,1231,2368,29,295,18,195,2369,609,586,1888,2641,892,761,44,1170,188,411,911
|
1.6564222106812256,1.7819528049746483,1.10136302234031,-0.19418721956236745,-0.39491714390968624,0.7392466032253644,0.4339317726253653,1.1685858128764244,-0.2938997945656019,0.36038744680166185,5.203448495367863,-0.11532915716857117,-1.1875599920679472,0.09751936170847361,-0.7062381065178011,-1.3475564028664557,0.11658683691935393,-0.017863872838918923,-0.017863872838918923,-0.017863872838918923,-0.056704463496115395,-0.25386051882213734,1.2186519515565648,0.09751936170847361,0.0784057608191252,-1.2785547987944277,2.3693825937809168,-1.00889493373649,0.8269144177911181,0.5249283688242936,-0.2938997945656019,4.917492659435559,-0.2938997945656019,-0.6850808626505676,0.304783521666528,0.8269144177911181,-1.0309922696079223,-1.0976844720755563,0.9136591415130947,2.947996335155421,0.8963828986355812,0.7568551780007351,2.027706771884764,-0.3746072665047304,0.2674983597767239,-0.5801746865595289,0.4522133253996353,-0.8129269700518783,0.04003907639528579,2.8379436574544386,0.999504346348033,0.9308994066578831,1.1853076769616102,0.23003816681518965,0.8443364414586735,0.2112417984925894,-0.43569894708233464,1.95164797870373,-0.03726011192253851,0.001484545851543285,0.001484545851543285,-0.31399754246940065,0.36038744680166185,5.246740467606561,-1.0976844720755563,0.0784057608191252,-0.43569894708233464,3.59506153369759,1.2352746846067904,4.212879893636516,1.6879761304662688,-0.43569894708233464,0.6149138846414414,0.6506311257033517,-0.23391832955023042,-0.5593666767876478,0.304783521666528,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696
| 3,425
|
Alcohol biosynthetic process
| 10
| 40
| 2.756023
| 0.005851
|
O75845,Q15392,Q14739,Q15800,O15269,Q16850,P04062,Q13510,P00374,Q15125
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
162,36,281,43,172,46,80,17,19,151
|
3317,172,1095,980,162,894,1898,19,3198,80,3405,494,1038,435,3019,1709,1214,1009,2483,1500,2066,1039,797,2927,2116,1250,17,2575,281,151,2346,36,1915,43,3153,46,2834,2408,290,972
|
-1.2556992813125427,1.7975170034836079,0.13560845959237622,0.2112417984925894,1.844043079409893,0.2861626937330696,-0.25386051882213734,4.12871911169829,-1.0309922696079223,2.62795906725318,-2.285109634377232,0.7919594158846363,0.17351522707522676,0.8790704925764257,-0.8129269700518783,-0.1743976571717926,0.0784057608191252,0.19240090545282404,-0.4972821326535668,-0.07619722251063903,-0.31399754246940065,0.17351522707522676,0.37883671691997084,-0.7274549681465066,-0.3341478103334249,0.05924575850806966,4.3200361894985715,-0.5386155010309926,1.268422139234549,1.9210387080998343,-0.43569894708233464,3.3886394720355844,-0.25386051882213734,3.2440577254623797,-0.9429962985415629,3.1775938115320623,-0.663982825714329,-0.4561715837491249,1.2518646944415734,0.23003816681518965
| 3,425
|
Lipoprotein metabolic process
| 7
| 18
| 2.753866
| 0.00589
|
Q9NUJ1,Q8N2K0,O43292,P04062,P50897,Q9BQE5,Q9Y2B2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,489,480,80,16,20,456
|
480,1061,1456,1834,80,3162,549,16,1115,489,1048,1924,829,20,906,2588,3,456
|
0.8094554736885617,0.15458450029912923,-0.056704463496115395,-0.23391832955023042,2.62795906725318,-0.9648974270030561,0.7039155427404739,4.33187072621963,0.13560845959237622,0.8094554736885617,0.17351522707522676,-0.25386051882213734,0.36038744680166185,4.007216364080601,0.2861626937330696,-0.5386155010309926,5.127245085124307,0.8617217363584101
| 3,425
|
Abnormal retinal artery morphology
| 10
| 24
| 2.753652
| 0.005893
|
P21964,P03915,P03886,P17900,P16278,P07602,Q13510,P10619,P00846,P06865
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
414,507,69,166,10,77,17,114,121,384
|
2512,2682,1830,121,69,507,384,77,1750,114,2690,10,166,414,2286,2811,2858,17,1190,1441,2134,552,2411,679
|
-0.5179207785497725,-0.6010399151957811,-0.23391832955023042,2.162978192726338,2.8655806296701516,0.7744260494954054,0.999504346348033,2.7125341584739417,-0.19418721956236745,2.2667784467407786,-0.6010399151957811,4.600231735570217,1.8285620188685285,0.9308994066578831,-0.4152809195710186,-0.663982825714329,-0.6850808626505676,4.3200361894985715,0.09751936170847361,-0.03726011192253851,-0.3341478103334249,0.7039155427404739,-0.4561715837491249,0.5249283688242936
| 3,425
|
Exopeptidase activity
| 10
| 33
| 2.750199
| 0.005956
|
P42785,Q9H3G5,Q92820,Q9NZ08,P10619,P55786,O14773,O75844,Q9HB40,Q9UIQ6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
37,106,238,113,114,182,89,154,30,95
|
89,154,516,710,626,114,2282,3276,3131,2195,37,2695,876,182,2902,1723,1078,398,3068,2080,238,1976,887,2909,106,3042,30,1332,3044,241,2467,113,95
|
2.5139509284160675,1.9056938106121482,0.7568551780007351,0.4704535329188798,0.5790392392161661,2.2667784467407786,-0.4152809195710186,-1.142484440376989,-0.9211596241735596,-0.3746072665047304,3.3755871954184276,-0.6010399151957811,0.304783521666528,1.7507404107076854,-0.7062381065178011,-0.1743976571717926,0.15458450029912923,0.9652727380057537,-0.8344482451084184,-0.31399754246940065,1.448448785568869,-0.27385423081555665,0.304783521666528,-0.7062381065178011,2.340187200505293,-0.8129269700518783,3.5053048346626823,0.020785433429236007,-0.8129269700518783,1.4322394553880162,-0.4766991906424338,2.281508618182512,2.441957508201226
| 3,425
|
Abnormal biliary tract morphology
| 12
| 23
| 2.74551
| 0.006042
|
Q9NZJ7,Q13043,P09601,Q9UJW0,Q5XKP0,Q14108,P07602,P14174,P04062,Q9NUN5,Q14739,O43681
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
552,550,102,266,561,13,77,333,80,145,281,311
|
311,1901,80,77,102,333,3377,3054,1587,2198,727,550,13,281,561,2085,826,565,145,552,266,1888,1660
|
1.1685858128764244,-0.25386051882213734,2.62795906725318,2.7125341584739417,2.3693825937809168,1.1182193515975896,-1.6303721469296955,-0.8344482451084184,-0.11532915716857117,-0.3746072665047304,0.4522133253996353,0.7039155427404739,4.530920591223999,1.268422139234549,0.6861926522306766,-0.31399754246940065,0.36038744680166185,0.6861926522306766,1.9973622966526008,0.7039155427404739,1.3179006469481906,-0.23391832955023042,-0.13496893733397167
| 3,425
|
EF-hand domain [IPR002048]
| 14
| 45
| 2.727893
| 0.006374
|
O43852,Q9NWM8,O95202,P07384,P80303,Q14257,Q8IYU8,Q9BRK5,O75071,Q9Y680,Q02818,P41208,O95302,Q96AY3
|
Sequence
|
InterPro Domain
|
interpro_domain
|
380,194,382,352,6,168,426,370,144,50,51,277,85,243
|
1237,380,144,2477,1140,382,85,352,1383,3288,2892,3275,2849,873,1754,277,1278,858,6,51,1677,1149,2120,168,2928,2162,1599,604,1862,2218,426,700,243,2135,1328,1403,370,633,849,194,2840,1337,586,455,50
|
0.05924575850806966,0.999504346348033,1.9973622966526008,-0.4972821326535668,0.11658683691935393,0.999504346348033,2.5568725955541236,1.0675480922862204,-0.017863872838918923,-1.1649875074107834,-0.7062381065178011,-1.142484440376989,-0.6850808626505676,0.304783521666528,-0.19418721956236745,1.2849471759441964,0.04003907639528579,0.32336109245226435,4.895159421570552,3.137486998744578,-0.15465833406450158,0.11658683691935393,-0.3341478103334249,1.8285620188685285,-0.7274549681465066,-0.3543509374216771,-0.11532915716857117,0.6149138846414414,-0.23391832955023042,-0.3746072665047304,0.9136591415130947,0.4886526246803302,1.4159992226041558,-0.3341478103334249,0.020785433429236007,-0.017863872838918923,1.0335956619699211,0.5790392392161661,0.34189565270391015,1.6879761304662688,-0.663982825714329,0.020785433429236007,0.6506311257033517,0.8617217363584101,3.1508751318963872
| 3,425
|
Steroid metabolism
| 7
| 30
| 2.723832
| 0.006453
|
O75845,O15118,Q15392,Q15800,Q16850,P04062,Q15125
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
162,97,36,43,46,80,151
|
97,980,162,894,1898,3198,80,1038,3232,1540,1009,1039,1218,2698,2927,2116,1250,2575,281,151,2346,36,1915,43,46,2632,972,2468,2370,1088
|
2.3984830795821077,0.2112417984925894,1.844043079409893,0.2861626937330696,-0.25386051882213734,-1.0309922696079223,2.62795906725318,0.17351522707522676,-1.075386542805351,-0.09573868680970035,0.19240090545282404,0.17351522707522676,0.0784057608191252,-0.6010399151957811,-0.7274549681465066,-0.3341478103334249,0.05924575850806966,-0.5386155010309926,1.268422139234549,1.9210387080998343,-0.43569894708233464,3.3886394720355844,-0.25386051882213734,3.2440577254623797,3.1775938115320623,-0.5593666767876478,0.23003816681518965,-0.4766991906424338,-0.43569894708233464,0.15458450029912923
| 3,425
|
Organic acid transmembrane transport
| 16
| 32
| 2.723172
| 0.006466
|
Q9UJS0,P33527,P50416,P23786,P08183,O43772,Q9UBX3,P31751,Q9BQT8,P53985,P41440,Q9Y619,O60831,P30825,Q9H2D1,Q15041
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
586,666,449,170,322,143,111,653,305,591,458,221,402,571,157,601
|
143,402,1140,2150,2320,322,2151,1274,170,871,571,693,653,2327,666,458,449,1674,591,1550,601,1015,3256,1022,1735,305,157,1201,1883,111,586,221
|
1.9973622966526008,0.9481038780076505,0.11658683691935393,-0.3543509374216771,-0.43569894708233464,1.1350418152893942,-0.3543509374216771,0.04003907639528579,1.813053367361717,0.304783521666528,0.6684312487998063,0.4886526246803302,0.5430054701796704,-0.43569894708233464,0.5249283688242936,0.8443364414586735,0.8617217363584101,-0.15465833406450158,0.6327920744221581,-0.09573868680970035,0.6149138846414414,0.19240090545282404,-1.0976844720755563,0.19240090545282404,-0.1743976571717926,1.2019963358891592,1.9056938106121482,0.09751936170847361,-0.23391832955023042,2.2962144810512832,0.6506311257033517,1.5290369140825837
| 3,425
|
Predicted secreted proteins
| 20
| 58
| 2.712855
| 0.006671
|
P80303,Q8NBM8,Q9HB40,Q08380,O60888,Q9UM22,O00584,P05067,Q02818,Q15165,Q9UMX5,P14174,Q9P2K2,Q9BTY2,Q8WUJ1,Q92520,Q9H6E4,P43490,Q9NZ08,O94919
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
6,146,30,159,161,169,164,297,51,72,76,333,344,214,110,369,371,112,113,250
|
164,811,2684,161,412,1141,250,710,778,297,2321,1704,2102,1706,2647,333,2003,2893,1838,1955,112,2017,2898,2773,1218,2523,6,3118,747,51,1147,159,2118,1391,3237,72,1078,1557,488,146,3368,110,2627,369,1731,595,1052,214,621,3042,371,3391,30,113,344,169,76,679
|
1.8285620188685285,0.36038744680166185,-0.6010399151957811,1.844043079409893,0.9308994066578831,0.11658683691935393,1.3670916483246272,0.4704535329188798,0.3972437030547652,1.2186519515565648,-0.43569894708233464,-0.1743976571717926,-0.3341478103334249,-0.1743976571717926,-0.5801746865595289,1.1182193515975896,-0.2938997945656019,-0.7062381065178011,-0.23391832955023042,-0.27385423081555665,2.281508618182512,-0.2938997945656019,-0.7062381065178011,-0.6429435893726733,0.0784057608191252,-0.5179207785497725,4.895159421570552,-0.8993869388026995,0.4339317726253653,3.137486998744578,0.11658683691935393,1.874922908999971,-0.3341478103334249,-0.017863872838918923,-1.075386542805351,2.8517725495914763,0.15458450029912923,-0.09573868680970035,0.8094554736885617,1.9821506505504098,-1.5586135678457116,2.3108961338926965,-0.5593666767876478,1.0335956619699211,-0.1743976571717926,0.6327920744221581,0.17351522707522676,1.5450638238651857,0.5969963442295187,-0.8129269700518783,1.0335956619699211,-1.825360370605193,3.5053048346626823,2.281508618182512,1.10136302234031,1.8285620188685285,2.7963313322340135,0.5249283688242936
| 3,425
|
Organic acid transmembrane transporter activity
| 10
| 24
| 2.697758
| 0.006981
|
Q9UJS0,P08183,Q96H78,Q9UBX3,Q9BQT8,P53985,P41440,Q9Y619,P30825,Q9H2D1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
586,322,47,111,305,591,458,221,571,157
|
1528,1746,2514,1140,322,2151,571,666,458,1674,591,1550,1015,1814,47,1022,1735,305,157,1201,1883,111,586,221
|
-0.09573868680970035,-0.19418721956236745,-0.5179207785497725,0.11658683691935393,1.1350418152893942,-0.3543509374216771,0.6684312487998063,0.5249283688242936,0.8443364414586735,-0.15465833406450158,0.6327920744221581,-0.09573868680970035,0.19240090545282404,-0.21402733728023318,3.1642440468955613,0.19240090545282404,-0.1743976571717926,1.2019963358891592,1.9056938106121482,0.09751936170847361,-0.23391832955023042,2.2962144810512832,0.6506311257033517,1.5290369140825837
| 3,425
|
Organophosphate ester transport
| 19
| 31
| 2.683787
| 0.007279
|
Q9BZF1,Q14108,Q96GC9,Q9Y5P4,Q9H2D1,Q9BSK2,P33527,Q4KMQ2,P12236,Q8WTV0,P08183,P41440,Q6NUK1,O00400,Q9NZD2,P12235,Q8TB61,P48739,Q08722
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
261,13,676,544,157,288,666,799,664,64,322,458,604,86,736,469,109,743,628
|
86,2514,813,949,3162,322,469,664,2284,2004,666,458,743,1218,1912,628,13,799,604,3256,109,64,676,1230,288,261,157,1406,736,2369,544
|
2.5425880302168293,-0.5179207785497725,0.36038744680166185,0.23003816681518965,-0.9648974270030561,1.1350418152893942,0.8269144177911181,0.5249283688242936,-0.4152809195710186,-0.2938997945656019,0.5249283688242936,0.8443364414586735,0.4339317726253653,0.0784057608191252,-0.25386051882213734,0.5790392392161661,4.530920591223999,0.37883671691997084,0.6149138846414414,-1.0976844720755563,2.3108961338926965,2.920606361818982,0.5249283688242936,0.0784057608191252,1.2518646944415734,1.3343293891978911,1.9056938106121482,-0.017863872838918923,0.4522133253996353,-0.43569894708233464,0.7216001253197305
| 3,425
|
Bulbar signs
| 10
| 15
| 2.675621
| 0.007459
|
P03915,P03886,P07602,Q99720,P04062,Q15043,P35637,P00846,O43681,Q9Y263
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
507,69,77,15,80,335,495,121,311,418
|
311,121,69,507,80,1312,77,3377,495,1542,335,656,15,552,418
|
1.1685858128764244,2.162978192726338,2.8655806296701516,0.7744260494954054,2.62795906725318,0.020785433429236007,2.7125341584739417,-1.6303721469296955,0.7919594158846363,-0.09573868680970035,1.1182193515975896,0.5430054701796704,4.355497276975648,0.7039155427404739,0.9308994066578831
| 3,425
|
Nucleophile aminohydrolases, N-terminal [IPR029055]
| 9
| 18
| 2.674208
| 0.007491
|
P28074,Q9UJ14,P28070,P20618,P49721,P28072,Q06203,Q99436,P60900
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
448,467,206,208,23,26,405,605,190
|
2681,638,208,2383,1348,1064,2692,2425,206,26,448,1353,23,190,405,1467,605,467
|
-0.6010399151957811,0.5610423537706956,1.5610608196920086,-0.4561715837491249,0.001484545851543285,0.15458450029912923,-0.6010399151957811,-0.4766991906424338,1.592965616941986,3.6839797644624737,0.8617217363584101,0.001484545851543285,3.734421078054943,1.703709953072957,0.9481038780076505,-0.056704463496115395,0.6149138846414414,0.8443364414586735
| 3,425
|
Regulation of blood pressure
| 6
| 21
| 2.672939
| 0.007519
|
P42785,P09601,P42892,Q9NZ08,Q9HB40,Q9UIQ6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
37,102,107,113,30,95
|
590,3362,916,558,102,2689,235,2426,37,107,667,2736,1766,1078,939,783,1820,30,113,95,1135
|
0.6327920744221581,-1.5111725380859105,0.2674983597767239,0.6861926522306766,2.3693825937809168,-0.6010399151957811,1.448448785568869,-0.4766991906424338,3.3755871954184276,2.325553674617119,0.5249283688242936,-0.6219627517160322,-0.19418721956236745,0.15458450029912923,0.24879026863223094,0.3972437030547652,-0.21402733728023318,3.5053048346626823,2.281508618182512,2.441957508201226,0.13560845959237622
| 3,425
|
Metalloprotease
| 13
| 26
| 2.671839
| 0.007544
|
Q99797,Q9BYT8,Q92905,P52888,O75976,P42892,Q7Z2K6,Q5JRX3,Q9NZ08,P55786,O75844,O43847,Q9UIQ6
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
223,358,260,167,516,107,398,460,113,182,154,568,95
|
1490,568,2890,154,516,626,2282,2003,107,167,182,460,1078,398,260,887,1930,223,358,3042,1332,3044,2467,113,95,1621
|
-0.07619722251063903,0.6684312487998063,-0.7062381065178011,1.9056938106121482,0.7568551780007351,0.5790392392161661,-0.4152809195710186,-0.2938997945656019,2.325553674617119,1.8285620188685285,1.7507404107076854,0.8443364414586735,0.15458450029912923,0.9652727380057537,1.3343293891978911,0.304783521666528,-0.25386051882213734,1.5129799522193979,1.0675480922862204,-0.8129269700518783,0.020785433429236007,-0.8129269700518783,-0.4766991906424338,2.281508618182512,2.441957508201226,-0.11532915716857117
| 3,425
|
Carbohydrate derivative transport
| 12
| 20
| 2.671663
| 0.007548
|
Q8WTV0,P12236,Q9NZJ7,Q08722,P07602,Q8TB61,P41440,Q6NUK1,Q96AA3,O00400,Q9NZD2,P12235
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,664,552,628,77,109,458,604,152,86,736,469
|
738,86,2514,813,949,77,469,664,458,1218,628,604,3256,109,64,152,1230,1406,736,552
|
0.4339317726253653,2.5425880302168293,-0.5179207785497725,0.36038744680166185,0.23003816681518965,2.7125341584739417,0.8269144177911181,0.5249283688242936,0.8443364414586735,0.0784057608191252,0.5790392392161661,0.6149138846414414,-1.0976844720755563,2.3108961338926965,2.920606361818982,1.9210387080998343,0.0784057608191252,-0.017863872838918923,0.4522133253996353,0.7039155427404739
| 3,425
|
Focal segmental glomerulosclerosis
| 7
| 25
| 2.665324
| 0.007691
|
Q96D53,P03886,Q14108,Q96AX1,Q8N1F7,O95470,P57740
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
491,69,13,209,279,118,436
|
1237,1172,118,914,69,507,936,436,2900,1149,1435,13,1506,2869,1325,279,2082,2498,1261,209,491,966,1742,1785,1744
|
0.05924575850806966,0.09751936170847361,2.2224410858737813,0.2674983597767239,2.8655806296701516,0.7744260494954054,0.24879026863223094,0.8790704925764257,-0.7062381065178011,0.11658683691935393,-0.03726011192253851,4.530920591223999,-0.07619722251063903,-0.6850808626505676,0.020785433429236007,1.2849471759441964,-0.31399754246940065,-0.4972821326535668,0.05924575850806966,1.5610608196920086,0.8094554736885617,0.23003816681518965,-0.1743976571717926,-0.19418721956236745,-0.1743976571717926
| 3,425
|
Cytochrome complex assembly
| 7
| 15
| 2.653426
| 0.007968
|
Q15070,Q69YU5,Q8N8Q8,Q9BRT2,Q9Y2R0,Q6DKK2,Q9BSK2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
520,8,272,476,54,185,288
|
709,1175,1544,919,520,8,185,529,272,999,476,288,2366,1888,54
|
0.4704535329188798,0.09751936170847361,-0.09573868680970035,0.2674983597767239,0.7568551780007351,4.669065000725359,1.7194151890935954,0.7392466032253644,1.3014399603266282,0.2112417984925894,0.8269144177911181,1.2518646944415734,-0.43569894708233464,-0.23391832955023042,3.097206606706352
| 3,425
|
primary active transporter
| 7
| 25
| 2.650819
| 0.00803
|
O60888,Q9GZP9,P20020,Q9NS69,P35670,Q8N4H5,Q9Y5J7
|
Functions
|
Panther Protein class
|
panther_protein_class
|
161,227,235,18,307,150,188
|
161,1577,1380,1457,916,1533,2190,724,235,307,2657,780,416,1015,882,538,150,1022,1083,227,1883,2368,18,1170,188
|
1.844043079409893,-0.11532915716857117,-0.017863872838918923,-0.056704463496115395,0.2674983597767239,-0.09573868680970035,-0.3746072665047304,0.4522133253996353,1.448448785568869,1.1853076769616102,-0.5801746865595289,0.3972437030547652,0.9308994066578831,0.19240090545282404,0.304783521666528,0.7216001253197305,1.95164797870373,0.19240090545282404,0.15458450029912923,1.4968927991314636,-0.23391832955023042,-0.43569894708233464,4.212879893636516,0.11658683691935393,1.7194151890935954
| 3,425
|
Sphingolipid metabolism
| 7
| 12
| 2.649726
| 0.008056
|
P16278,P06280,O15269,P04062,Q13510,O95470,Q9NRA0
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
10,139,172,80,17,118,290
|
172,1095,311,118,80,139,3377,10,527,17,290,1822
|
1.7975170034836079,0.13560845959237622,1.1685858128764244,2.2224410858737813,2.62795906725318,2.057946899190213,-1.6303721469296955,4.600231735570217,0.7392466032253644,4.3200361894985715,1.2518646944415734,-0.21402733728023318
| 3,425
|
Skin nodule
| 12
| 20
| 2.649585
| 0.008059
|
P31749,Q8NBM4,P06280,P11802,Q13510,Q9NZ08,P49327,P35637,Q92990,P52732,Q9NSE4,P34913
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
693,717,139,429,17,113,526,495,675,155,512,470
|
1379,2804,139,429,724,952,693,470,1755,495,875,526,155,3166,17,717,675,512,113,1235
|
-0.017863872838918923,-0.663982825714329,2.057946899190213,0.8963828986355812,0.4522133253996353,0.23003816681518965,0.4886526246803302,0.8269144177911181,-0.19418721956236745,0.7919594158846363,0.304783521666528,0.7392466032253644,1.9056938106121482,-0.9648974270030561,4.3200361894985715,0.4704535329188798,0.5249283688242936,0.7744260494954054,2.281508618182512,0.0784057608191252
| 3,425
|
Cholesterol metabolism
| 6
| 26
| 2.641463
| 0.008255
|
O15118,Q15392,Q15800,Q16850,P04062,Q15125
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
97,36,43,46,80,151
|
97,980,894,1898,3198,80,1038,3232,1540,1009,1039,1218,2698,2927,2116,1250,2575,281,151,2346,36,1915,43,46,972,2468
|
2.3984830795821077,0.2112417984925894,0.2861626937330696,-0.25386051882213734,-1.0309922696079223,2.62795906725318,0.17351522707522676,-1.075386542805351,-0.09573868680970035,0.19240090545282404,0.17351522707522676,0.0784057608191252,-0.6010399151957811,-0.7274549681465066,-0.3341478103334249,0.05924575850806966,-0.5386155010309926,1.268422139234549,1.9210387080998343,-0.43569894708233464,3.3886394720355844,-0.25386051882213734,3.2440577254623797,3.1775938115320623,0.23003816681518965,-0.4766991906424338
| 3,425
|
Ascites
| 12
| 26
| 2.641145
| 0.008263
|
O95235,O15118,P10644,Q13043,Q01844,Q14108,Q9NSD9,P04062,Q13510,O60566,O75787,Q14739
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
383,97,163,550,578,13,565,80,17,179,590,281
|
97,2556,179,590,383,80,163,2892,2948,3289,2198,1218,1910,2202,2022,1282,578,2527,550,17,13,281,1646,617,565,1660
|
2.3984830795821077,-0.5386155010309926,1.7663606487132952,0.6327920744221581,0.999504346348033,2.62795906725318,1.844043079409893,-0.7062381065178011,-0.7487318629297377,-1.1649875074107834,-0.3746072665047304,0.0784057608191252,-0.25386051882213734,-0.3746072665047304,-0.2938997945656019,0.04003907639528579,0.6506311257033517,-0.5179207785497725,0.7039155427404739,4.3200361894985715,4.530920591223999,1.268422139234549,-0.13496893733397167,0.5969963442295187,0.6861926522306766,-0.13496893733397167
| 3,425
|
Secondary alcohol metabolic process
| 14
| 44
| 2.640438
| 0.00828
|
Q8WTV0,O75845,Q15125,Q15392,O15118,Q15800,P05067,Q16850,P04062,Q14534,Q9BQE5,Q14739,P16435,P34913
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,162,151,36,97,43,297,46,80,407,20,281,435,470
|
97,2887,980,162,1379,894,1898,3198,80,297,494,1038,435,3232,470,1540,1009,2483,1500,875,2565,3349,2066,1039,1218,2698,2927,2116,1250,2575,407,281,151,2346,36,1915,43,46,64,3257,20,806,972,2468
|
2.3984830795821077,-0.7062381065178011,0.2112417984925894,1.844043079409893,-0.017863872838918923,0.2861626937330696,-0.25386051882213734,-1.0309922696079223,2.62795906725318,1.2186519515565648,0.7919594158846363,0.17351522707522676,0.8790704925764257,-1.075386542805351,0.8269144177911181,-0.09573868680970035,0.19240090545282404,-0.4972821326535668,-0.07619722251063903,0.304783521666528,-0.5386155010309926,-1.3939257358204213,-0.31399754246940065,0.17351522707522676,0.0784057608191252,-0.6010399151957811,-0.7274549681465066,-0.3341478103334249,0.05924575850806966,-0.5386155010309926,0.9481038780076505,1.268422139234549,1.9210387080998343,-0.43569894708233464,3.3886394720355844,-0.25386051882213734,3.2440577254623797,3.1775938115320623,2.920606361818982,-1.0976844720755563,4.007216364080601,0.37883671691997084,0.23003816681518965,-0.4766991906424338
| 3,425
|
Aminoglycan metabolic process
| 7
| 18
| 2.638525
| 0.008327
|
O43505,P54802,P16278,Q8NCH0,P15586,P06865,Q7LGA3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
104,202,10,123,345,384,350
|
104,1945,2764,576,384,1750,345,10,202,2699,350,123,783,1162,806,971,442,1269
|
2.340187200505293,-0.27385423081555665,-0.6429435893726733,0.6506311257033517,0.999504346348033,-0.19418721956236745,1.0844726591413512,4.600231735570217,1.6247523908291193,-0.6010399151957811,1.0844726591413512,2.162978192726338,0.3972437030547652,0.11658683691935393,0.37883671691997084,0.23003816681518965,0.8790704925764257,0.05924575850806966
| 3,425
|
Mitochondrial transport
| 31
| 94
| 2.637059
| 0.008363
|
Q99595,O60830,Q15070,Q8N8Q8,P45880,O43772,Q96EK5,Q9NS69,Q9Y5J9,Q8N4H5,Q15388,P30419,P24539,P23786,Q9Y584,O95831,O75964,P55786,Q9Y5J7,Q9UJS0,P50416,P49257,Q5JRX3,O14925,P12235,Q99797,O14737,Q9UBX3,P30536,O95429,P00846
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,2,520,272,14,143,530,18,411,150,416,549,547,170,44,557,56,182,188,586,449,323,460,340,469,223,234,111,242,245,121
|
680,1092,234,340,777,740,143,2,1456,1172,2890,1496,56,1380,913,2604,245,2376,557,1457,121,2805,949,1178,1665,1424,3182,469,2771,170,547,2851,3132,549,242,2732,839,2483,14,3204,323,667,779,449,1247,725,182,1249,1185,2337,727,1250,520,416,2577,629,959,2662,460,604,2665,1862,2218,150,1440,272,1362,1117,825,530,1263,1688,1,223,2835,1123,2368,2044,18,1128,2410,111,2094,586,1412,1888,1657,892,761,44,1170,188,411,911
|
0.5068108281574367,0.13560845959237622,1.448448785568869,1.10136302234031,0.3972437030547652,0.4339317726253653,1.9973622966526008,5.203448495367863,-0.056704463496115395,0.09751936170847361,-0.7062381065178011,-0.07619722251063903,3.0567507737172264,-0.017863872838918923,0.2674983597767239,-0.5593666767876478,1.3997279417347968,-0.4561715837491249,0.6861926522306766,-0.056704463496115395,2.162978192726338,-0.663982825714329,0.23003816681518965,0.09751936170847361,-0.15465833406450158,-0.03726011192253851,-1.00889493373649,0.8269144177911181,-0.6429435893726733,1.813053367361717,0.7039155427404739,-0.6850808626505676,-0.9211596241735596,0.7039155427404739,1.4159992226041558,-0.6219627517160322,0.34189565270391015,-0.4972821326535668,4.496083243944842,-1.0309922696079223,1.1350418152893942,0.5249283688242936,0.3972437030547652,0.8617217363584101,0.05924575850806966,0.4522133253996353,1.7507404107076854,0.05924575850806966,0.09751936170847361,-0.43569894708233464,0.4522133253996353,0.05924575850806966,0.7568551780007351,0.9308994066578831,-0.5386155010309926,0.5790392392161661,0.23003816681518965,-0.5801746865595289,0.8443364414586735,0.6149138846414414,-0.5801746865595289,-0.23391832955023042,-0.3746072665047304,1.95164797870373,-0.03726011192253851,1.3014399603266282,0.001484545851543285,0.13560845959237622,0.36038744680166185,0.7392466032253644,0.05924575850806966,-0.15465833406450158,5.246740467606561,1.5129799522193979,-0.663982825714329,0.13560845959237622,-0.43569894708233464,-0.2938997945656019,4.212879893636516,0.13560845959237622,-0.4561715837491249,2.2962144810512832,-0.31399754246940065,0.6506311257033517,-0.017863872838918923,-0.23391832955023042,-0.13496893733397167,0.304783521666528,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696
| 3,425
|
Localization within membrane
| 69
| 197
| 2.636508
| 0.008376
|
O43805,P35613,O15321,Q15070,O43752,O00264,Q9BXS4,Q8N8Q8,Q9NV70,P31751,Q9NS69,Q9BTX1,Q15436,P98194,Q9Y5J9,Q9UJY4,Q6VY07,Q9NZJ7,P60033,P30419,P43307,O00560,P40855,Q9Y584,Q15904,Q9UEU0,P49069,Q9UHB9,Q96KC2,Q96A33,Q8N4V1,O43681,Q9Y5J7,O00471,Q9UPN3,P46379,P31749,Q14168,Q4J6C6,Q8IYI6,P07602,Q9H4A6,Q5EBL8,P41440,Q15629,O60725,Q9BZG1,Q99805,Q15363,Q15041,O15118,Q86YV9,Q9Y512,Q15057,Q92544,P50570,O14737,Q9HD45,P57105,Q15006,Q9HD47,O15027,Q9H223,O75436,O14972,Q9HD20,Q5BJH7,O95429,Q9UGP8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,254,378,520,379,514,138,272,657,653,18,147,781,780,411,807,671,552,292,549,40,419,422,44,177,706,431,52,184,441,186,311,188,689,455,63,693,196,580,326,77,596,459,458,84,88,477,606,93,601,97,750,761,360,753,745,234,362,483,748,503,739,633,741,117,244,247,245,389
|
1789,2555,2886,514,689,419,2600,234,1528,117,1942,739,97,1346,378,1747,812,311,379,1994,128,1575,88,852,1137,741,1834,1242,2150,853,3212,1380,2686,245,2057,1533,2320,77,1665,3077,1100,1951,2154,3348,3304,1103,549,2325,693,653,1384,2732,2330,254,2429,2011,422,1842,458,40,2012,63,1588,431,1758,745,2610,3116,2657,2200,920,483,292,2658,2569,2570,1069,1804,2900,1548,2158,3266,2289,780,2203,2699,1964,1148,2254,2957,1505,3409,1850,2780,3236,2025,1808,2206,196,1644,2928,1188,748,601,360,520,1853,2395,93,781,84,177,1679,580,2822,2662,247,459,821,2579,671,2355,1158,1920,750,326,1972,186,1771,272,1361,3368,2131,2829,1117,753,441,1119,2036,2934,1563,184,802,1399,1263,1514,606,147,138,477,2835,633,906,596,849,2674,1447,244,1330,362,503,1372,2791,18,1408,657,552,3089,1128,1486,706,389,52,1825,1087,807,3211,2881,2509,1167,973,1133,455,1451,1888,1234,1657,892,1169,3369,761,44,1170,188,411,911,2553
|
-0.21402733728023318,-0.5386155010309926,-0.7062381065178011,0.7568551780007351,0.4886526246803302,0.9136591415130947,-0.5593666767876478,1.448448785568869,-0.09573868680970035,2.2224410858737813,-0.27385423081555665,0.4339317726253653,2.3984830795821077,0.001484545851543285,0.999504346348033,-0.19418721956236745,0.36038744680166185,1.1685858128764244,0.999504346348033,-0.2938997945656019,2.118117615036976,-0.11532915716857117,2.528280837326959,0.32336109245226435,0.11658683691935393,0.4339317726253653,-0.23391832955023042,0.05924575850806966,-0.3543509374216771,0.32336109245226435,-1.0531559749508097,-0.017863872838918923,-0.6010399151957811,1.3997279417347968,-0.31399754246940065,-0.09573868680970035,-0.43569894708233464,2.7125341584739417,-0.15465833406450158,-0.8560317012161593,0.13560845959237622,-0.27385423081555665,-0.3543509374216771,-1.3939257358204213,-1.2102024240548812,0.13560845959237622,0.7039155427404739,-0.43569894708233464,0.4886526246803302,0.5430054701796704,-0.017863872838918923,-0.6219627517160322,-0.43569894708233464,1.3507263392996962,-0.4766991906424338,-0.2938997945656019,0.9136591415130947,-0.23391832955023042,0.8443364414586735,3.296890926305054,-0.2938997945656019,2.947996335155421,-0.11532915716857117,0.8963828986355812,-0.19418721956236745,0.4339317726253653,-0.5593666767876478,-0.8993869388026995,-0.5801746865595289,-0.3746072665047304,0.2674983597767239,0.8094554736885617,1.2352746846067904,-0.5801746865595289,-0.5386155010309926,-0.5386155010309926,0.15458450029912923,-0.21402733728023318,-0.7062381065178011,-0.09573868680970035,-0.3543509374216771,-1.1200502676254012,-0.4152809195710186,0.3972437030547652,-0.3746072665047304,-0.6010399151957811,-0.27385423081555665,0.11658683691935393,-0.39491714390968624,-0.7487318629297377,-0.07619722251063903,-2.609782640678871,-0.23391832955023042,-0.6429435893726733,-1.075386542805351,-0.2938997945656019,-0.21402733728023318,-0.3746072665047304,1.6722135928008373,-0.13496893733397167,-0.7274549681465066,0.09751936170847361,0.4339317726253653,0.6149138846414414,1.0505891507074792,0.7568551780007351,-0.23391832955023042,-0.4561715837491249,2.4564023437522535,0.3972437030547652,2.599591402744298,1.7819528049746483,-0.15465833406450158,0.6506311257033517,-0.663982825714329,-0.5801746865595289,1.3997279417347968,0.8443364414586735,0.36038744680166185,-0.5386155010309926,0.5249283688242936,-0.43569894708233464,0.11658683691935393,-0.25386051882213734,0.4339317726253653,1.1350418152893942,-0.27385423081555665,1.7194151890935954,-0.19418721956236745,1.3014399603266282,0.001484545851543285,-1.5586135678457116,-0.3341478103334249,-0.663982825714329,0.13560845959237622,0.4339317726253653,0.8790704925764257,0.13560845959237622,-0.2938997945656019,-0.7274549681465066,-0.09573868680970035,1.7507404107076854,0.37883671691997084,-0.017863872838918923,0.05924575850806966,-0.07619722251063903,0.6149138846414414,1.9821506505504098,2.0730281075790966,0.8269144177911181,-0.663982825714329,0.5790392392161661,0.2861626937330696,0.6327920744221581,0.34189565270391015,-0.5801746865595289,-0.03726011192253851,1.4159992226041558,0.020785433429236007,1.0505891507074792,0.7919594158846363,0.001484545851543285,-0.6429435893726733,4.212879893636516,-0.017863872838918923,0.5430054701796704,0.7039155427404739,-0.8560317012161593,0.13560845959237622,-0.056704463496115395,0.4886526246803302,0.999504346348033,3.137486998744578,-0.21402733728023318,0.15458450029912923,0.37883671691997084,-1.0309922696079223,-0.6850808626505676,-0.4972821326535668,0.11658683691935393,0.23003816681518965,0.13560845959237622,0.8617217363584101,-0.03726011192253851,-0.23391832955023042,0.0784057608191252,-0.13496893733397167,0.304783521666528,0.11658683691935393,-1.5586135678457116,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696,-0.5179207785497725
| 3,425
|
Protein targeting to mitochondrion
| 15
| 56
| 2.635898
| 0.008391
|
Q99797,Q99595,O60830,O14925,O95429,P49257,Q9Y584,O14737,Q9NS69,Q9Y5J9,Q9Y5J7,P30536,Q8N4H5,P55786,Q15388
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
223,1,2,340,245,323,44,234,18,411,188,242,150,182,416
|
680,1092,234,340,777,740,2,1456,2890,1380,913,2604,245,2376,557,1457,1665,3182,2771,242,2732,323,667,1247,182,2337,727,1250,416,2577,959,2662,460,2665,150,1440,1362,825,1688,1,223,2835,1123,2368,18,1128,2410,2094,1657,892,761,44,1170,188,411,911
|
0.5068108281574367,0.13560845959237622,1.448448785568869,1.10136302234031,0.3972437030547652,0.4339317726253653,5.203448495367863,-0.056704463496115395,-0.7062381065178011,-0.017863872838918923,0.2674983597767239,-0.5593666767876478,1.3997279417347968,-0.4561715837491249,0.6861926522306766,-0.056704463496115395,-0.15465833406450158,-1.00889493373649,-0.6429435893726733,1.4159992226041558,-0.6219627517160322,1.1350418152893942,0.5249283688242936,0.05924575850806966,1.7507404107076854,-0.43569894708233464,0.4522133253996353,0.05924575850806966,0.9308994066578831,-0.5386155010309926,0.23003816681518965,-0.5801746865595289,0.8443364414586735,-0.5801746865595289,1.95164797870373,-0.03726011192253851,0.001484545851543285,0.36038744680166185,-0.15465833406450158,5.246740467606561,1.5129799522193979,-0.663982825714329,0.13560845959237622,-0.43569894708233464,4.212879893636516,0.13560845959237622,-0.4561715837491249,-0.31399754246940065,-0.13496893733397167,0.304783521666528,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696
| 3,425
|
protein modifying enzyme
| 8
| 27
| 2.63194
| 0.00849
|
Q92791,O60476,P50897,Q86YN1,Q6P2P2,O60725,Q9UMR5,P13674
|
Functions
|
Panther Protein class
|
panther_protein_class
|
67,302,16,212,408,88,59,222
|
2513,1344,1171,662,302,2684,1832,88,412,222,16,935,2253,2024,2212,2348,537,408,1223,1226,212,2746,67,1874,1936,59,2884
|
-0.5179207785497725,0.001484545851543285,0.09751936170847361,0.5249283688242936,1.2019963358891592,-0.6010399151957811,-0.23391832955023042,2.528280837326959,0.9308994066578831,1.5129799522193979,4.33187072621963,0.24879026863223094,-0.39491714390968624,-0.2938997945656019,-0.3746072665047304,-0.43569894708233464,0.7216001253197305,0.9481038780076505,0.0784057608191252,0.0784057608191252,1.5450638238651857,-0.6219627517160322,2.879367974649712,-0.23391832955023042,-0.25386051882213734,3.002533477096661,-0.6850808626505676
| 3,425
|
Corneal opacity
| 25
| 60
| 2.62369
| 0.008698
|
O96028,O95202,P16278,P06280,P51648,Q13510,Q06136,Q9Y4P3,O75844,P52732,O75845,P40855,P35670,O75569,O60566,Q9Y2B2,P04066,P04062,Q6NUK1,P34913,O43505,P10619,Q8NAT1,Q9NVI7,Q96J42
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
131,382,10,139,141,17,527,679,154,155,162,422,307,555,179,456,576,80,604,470,104,114,368,647,126
|
2761,1891,661,104,2556,1830,179,3145,1577,555,154,162,1998,382,1900,131,1901,80,576,139,1629,114,10,951,1275,470,2286,307,422,2953,141,155,919,1545,920,2858,1677,527,2958,17,1808,1190,1646,1395,749,604,1325,368,1441,126,3391,647,1300,3260,972,2411,456,679,810,2414
|
-0.6429435893726733,-0.25386051882213734,0.5249283688242936,2.340187200505293,-0.5386155010309926,-0.23391832955023042,1.7663606487132952,-0.9429962985415629,-0.11532915716857117,0.6861926522306766,1.9056938106121482,1.844043079409893,-0.2938997945656019,0.999504346348033,-0.25386051882213734,2.10311335779798,-0.25386051882213734,2.62795906725318,0.6506311257033517,2.057946899190213,-0.13496893733397167,2.2667784467407786,4.600231735570217,0.23003816681518965,0.04003907639528579,0.8269144177911181,-0.4152809195710186,1.1853076769616102,0.9136591415130947,-0.7487318629297377,2.027706771884764,1.9056938106121482,0.2674983597767239,-0.09573868680970035,0.2674983597767239,-0.6850808626505676,-0.15465833406450158,0.7392466032253644,-0.7487318629297377,4.3200361894985715,-0.21402733728023318,0.09751936170847361,-0.13496893733397167,-0.017863872838918923,0.4339317726253653,0.6149138846414414,0.020785433429236007,1.0335956619699211,-0.03726011192253851,2.133096436106864,-1.825360370605193,0.5610423537706956,0.04003907639528579,-1.0976844720755563,0.23003816681518965,-0.4561715837491249,0.8617217363584101,0.5249283688242936,0.37883671691997084,-0.4561715837491249
| 3,425
|
Increased bone mineral density
| 7
| 25
| 2.618797
| 0.008824
|
Q15125,Q15392,P54802,Q13126,Q14108,P04062,Q14739
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
151,36,202,11,13,80,281
|
1830,1901,80,951,1275,3304,2895,2286,3392,202,3059,2858,1219,11,13,281,335,1190,151,36,1395,1441,2411,1235,679
|
-0.23391832955023042,-0.25386051882213734,2.62795906725318,0.23003816681518965,0.04003907639528579,-1.2102024240548812,-0.7062381065178011,-0.4152809195710186,-1.8501181590001228,1.6247523908291193,-0.8344482451084184,-0.6850808626505676,0.0784057608191252,4.577181521435861,4.530920591223999,1.268422139234549,1.1182193515975896,0.09751936170847361,1.9210387080998343,3.3886394720355844,-0.017863872838918923,-0.03726011192253851,-0.4561715837491249,0.0784057608191252,0.5249283688242936
| 3,425
|
Clumsiness
| 8
| 24
| 2.61472
| 0.00893
|
P07602,Q13510,P35670,Q9NP73,O14773,O43681,Q9NR77,O75503
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
77,17,307,376,89,311,29,62
|
680,2761,89,1891,311,709,62,1312,77,3377,2518,2060,307,899,17,386,2443,2078,2497,943,376,29,552,1450
|
0.5068108281574367,-0.6429435893726733,2.5139509284160675,-0.25386051882213734,1.1685858128764244,0.4704535329188798,2.947996335155421,0.020785433429236007,2.7125341584739417,-1.6303721469296955,-0.5179207785497725,-0.31399754246940065,1.1853076769616102,0.2861626937330696,4.3200361894985715,0.999504346348033,-0.4766991906424338,-0.31399754246940065,-0.4972821326535668,0.24879026863223094,1.0165674522554908,3.59506153369759,0.7039155427404739,-0.03726011192253851
| 3,425
|
calmodulin-related
| 6
| 13
| 2.613189
| 0.00897
|
O43852,Q14257,P80303,Q9BRK5,Q02818,P41208
|
Functions
|
Panther Protein class
|
panther_protein_class
|
380,168,6,370,51,277
|
380,873,1754,277,6,51,168,2162,426,2135,595,1403,370
|
0.999504346348033,0.304783521666528,-0.19418721956236745,1.2849471759441964,4.895159421570552,3.137486998744578,1.8285620188685285,-0.3543509374216771,0.9136591415130947,-0.3341478103334249,0.6327920744221581,-0.017863872838918923,1.0335956619699211
| 3,425
|
Sensorimotor neuropathy
| 13
| 32
| 2.613181
| 0.00897
|
P03915,Q9NSE4,Q9NZJ7,P07196,P03886,Q8N2K0,Q5KU26,O60313,P07602,P41440,Q9Y2R0,P00846,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
507,512,552,447,69,489,486,482,77,458,54,121,29
|
1306,1095,482,557,914,121,69,507,916,447,77,1347,3079,2924,2332,458,1672,2198,3059,3277,1283,1761,1768,486,489,656,2671,29,512,552,54,1621
|
0.020785433429236007,0.13560845959237622,0.8094554736885617,0.6861926522306766,0.2674983597767239,2.162978192726338,2.8655806296701516,0.7744260494954054,0.2674983597767239,0.8617217363584101,2.7125341584739417,0.001484545851543285,-0.8560317012161593,-0.7274549681465066,-0.43569894708233464,0.8443364414586735,-0.15465833406450158,-0.3746072665047304,-0.8344482451084184,-1.142484440376989,0.04003907639528579,-0.19418721956236745,-0.19418721956236745,0.8094554736885617,0.8094554736885617,0.5430054701796704,-0.5801746865595289,3.59506153369759,0.7744260494954054,0.7039155427404739,3.097206606706352,-0.11532915716857117
| 3,425
|
Glycoside hydrolase superfamily [IPR017853]
| 7
| 15
| 2.611982
| 0.009002
|
P16278,P54802,P06280,P04062,O60502,Q9BTY2,P06865
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
10,202,139,80,267,214,384
|
267,80,576,139,384,1750,2151,421,10,1668,202,2527,2621,214,2039
|
1.3014399603266282,2.62795906725318,0.6506311257033517,2.057946899190213,0.999504346348033,-0.19418721956236745,-0.3543509374216771,0.9136591415130947,4.600231735570217,-0.15465833406450158,1.6247523908291193,-0.5179207785497725,-0.5593666767876478,1.5450638238651857,-0.2938997945656019
| 3,425
|
Protein targeting
| 31
| 122
| 2.610496
| 0.009041
|
Q99595,O60830,Q9Y5M8,Q14108,Q9NS69,Q9Y5J9,Q8N4H5,Q15388,P43307,O00560,P46934,P40855,Q9Y584,Q9UHB9,P55786,O43681,Q9Y5J7,P46379,P49257,Q5JRX3,P20645,Q15629,O60725,O14925,Q16543,Q99797,O14737,P30536,Q5BJH7,O95429,Q9UGP8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,2,135,13,18,411,150,416,40,419,423,422,44,52,182,311,188,63,323,460,457,84,88,340,347,223,234,242,247,245,389
|
2555,680,1092,2886,419,2600,234,340,777,740,311,1994,88,2,1456,1577,2890,3212,1380,913,2604,245,2376,557,1457,1665,3077,3182,1835,795,2771,457,1103,1667,2950,242,2325,653,1276,2732,2011,422,40,63,423,323,1758,667,2610,1247,182,920,483,2658,3001,2570,2900,1547,1041,1590,1357,2337,2203,727,1505,1250,13,579,601,416,84,2577,347,959,2662,247,460,941,2355,1158,1260,2665,1972,150,1440,1362,2829,825,1000,1051,1514,1688,686,2225,1,223,2835,1123,1447,2368,18,1408,1128,2410,389,52,1825,2094,609,1167,1133,587,1657,892,1169,761,44,1170,188,411,911,135
|
-0.5386155010309926,0.5068108281574367,0.13560845959237622,-0.7062381065178011,0.9136591415130947,-0.5593666767876478,1.448448785568869,1.10136302234031,0.3972437030547652,0.4339317726253653,1.1685858128764244,-0.2938997945656019,2.528280837326959,5.203448495367863,-0.056704463496115395,-0.11532915716857117,-0.7062381065178011,-1.0531559749508097,-0.017863872838918923,0.2674983597767239,-0.5593666767876478,1.3997279417347968,-0.4561715837491249,0.6861926522306766,-0.056704463496115395,-0.15465833406450158,-0.8560317012161593,-1.00889493373649,-0.23391832955023042,0.37883671691997084,-0.6429435893726733,0.8443364414586735,0.13560845959237622,-0.15465833406450158,-0.7487318629297377,1.4159992226041558,-0.43569894708233464,0.5430054701796704,0.04003907639528579,-0.6219627517160322,-0.2938997945656019,0.9136591415130947,3.296890926305054,2.947996335155421,0.9136591415130947,1.1350418152893942,-0.19418721956236745,0.5249283688242936,-0.5593666767876478,0.05924575850806966,1.7507404107076854,0.2674983597767239,0.8094554736885617,-0.5801746865595289,-0.79146743676524,-0.5386155010309926,-0.7062381065178011,-0.09573868680970035,0.17351522707522676,-0.11532915716857117,0.001484545851543285,-0.43569894708233464,-0.3746072665047304,0.4522133253996353,-0.07619722251063903,0.05924575850806966,4.530920591223999,0.6506311257033517,0.6149138846414414,0.9308994066578831,2.599591402744298,-0.5386155010309926,1.0844726591413512,0.23003816681518965,-0.5801746865595289,1.3997279417347968,0.8443364414586735,0.24879026863223094,-0.43569894708233464,0.11658683691935393,0.05924575850806966,-0.5801746865595289,-0.27385423081555665,1.95164797870373,-0.03726011192253851,0.001484545851543285,-0.663982825714329,0.36038744680166185,0.2112417984925894,0.17351522707522676,-0.07619722251063903,-0.15465833406450158,0.5068108281574367,-0.3746072665047304,5.246740467606561,1.5129799522193979,-0.663982825714329,0.13560845959237622,-0.03726011192253851,-0.43569894708233464,4.212879893636516,-0.017863872838918923,0.13560845959237622,-0.4561715837491249,0.999504346348033,3.137486998744578,-0.21402733728023318,-0.31399754246940065,0.6149138846414414,0.11658683691935393,0.13560845959237622,0.6506311257033517,-0.13496893733397167,0.304783521666528,0.11658683691935393,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696,2.10311335779798
| 3,425
|
Monooxygenase activity
| 6
| 8
| 2.602714
| 0.009249
|
P09601,Q15800,Q16850,Q6UW02,P30519,Q9BU89
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
102,43,46,336,21,224
|
102,21,797,407,43,46,336,224
|
2.3693825937809168,3.921251120524279,0.37883671691997084,0.9481038780076505,3.2440577254623797,3.1775938115320623,1.1182193515975896,1.5129799522193979
| 3,425
|
Nuclear inner membrane
| 8
| 23
| 2.598512
| 0.009363
|
Q9H1E5,O94901,P50402,Q8IXM6,Q99720,Q14728,Q14739,O75844
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
262,263,517,203,15,366,281,154
|
154,894,263,1797,2108,1542,517,2434,1013,1504,766,366,281,1769,900,203,617,1605,15,1690,262,1004,1235
|
1.9056938106121482,0.2861626937330696,1.3179006469481906,-0.21402733728023318,-0.3341478103334249,-0.09573868680970035,0.7568551780007351,-0.4766991906424338,0.19240090545282404,-0.07619722251063903,0.41560864305026346,1.0335956619699211,1.268422139234549,-0.19418721956236745,0.2861626937330696,1.6247523908291193,0.5969963442295187,-0.11532915716857117,4.355497276975648,-0.15465833406450158,1.3343293891978911,0.2112417984925894,0.0784057608191252
| 3,425
|
Steroid biosynthesis
| 6
| 26
| 2.596181
| 0.009427
|
O75845,Q15125,Q15392,Q15800,Q16850,Q14739
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
162,151,36,43,46,281
|
162,894,3198,1038,1009,1500,1039,2927,2116,1250,2575,281,151,2346,36,1915,43,46,299,1865,2400,2633,1124,972,2370,1088
|
1.844043079409893,0.2861626937330696,-1.0309922696079223,0.17351522707522676,0.19240090545282404,-0.07619722251063903,0.17351522707522676,-0.7274549681465066,-0.3341478103334249,0.05924575850806966,-0.5386155010309926,1.268422139234549,1.9210387080998343,-0.43569894708233464,3.3886394720355844,-0.25386051882213734,3.2440577254623797,3.1775938115320623,1.2186519515565648,-0.23391832955023042,-0.4561715837491249,-0.5593666767876478,0.13560845959237622,0.23003816681518965,-0.43569894708233464,0.15458450029912923
| 3,425
|
serine protease
| 7
| 21
| 2.593365
| 0.009504
|
P42785,Q16740,Q9H3G5,P67812,P10619,O14773,Q9HB40
|
Functions
|
Panther Protein class
|
panther_protein_class
|
37,74,106,269,114,89,30
|
89,777,1792,114,3163,2153,3131,1587,37,817,269,74,308,580,1115,3068,489,3240,1123,106,30
|
2.5139509284160675,0.3972437030547652,-0.21402733728023318,2.2667784467407786,-0.9648974270030561,-0.3543509374216771,-0.9211596241735596,-0.11532915716857117,3.3755871954184276,0.36038744680166185,1.3014399603266282,2.7963313322340135,1.1853076769616102,0.6506311257033517,0.13560845959237622,-0.8344482451084184,0.8094554736885617,-1.075386542805351,0.13560845959237622,2.340187200505293,3.5053048346626823
| 3,425
|
Polyneuropathy
| 11
| 21
| 2.571241
| 0.010133
|
P03915,Q9NZJ7,Q8N2K0,P03886,P04066,O60313,P07602,P35670,O95831,P00846,Q15041
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
507,552,489,69,576,482,77,307,557,121,601
|
482,663,557,1900,121,69,507,576,77,2242,2326,307,1964,601,1768,2078,489,2497,1406,552,2313
|
0.8094554736885617,0.5249283688242936,0.6861926522306766,-0.25386051882213734,2.162978192726338,2.8655806296701516,0.7744260494954054,0.6506311257033517,2.7125341584739417,-0.39491714390968624,-0.43569894708233464,1.1853076769616102,-0.27385423081555665,0.6149138846414414,-0.19418721956236745,-0.31399754246940065,0.8094554736885617,-0.4972821326535668,-0.017863872838918923,0.7039155427404739,-0.4152809195710186
| 3,425
|
Translocation
| 11
| 52
| 2.565275
| 0.010309
|
Q99595,O60830,Q9Y584,Q9NS69,Q9BTX1,P41208,Q9Y5J9,Q8N1F7,Q15629,O14925,Q9Y5J7
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
1,2,44,18,147,277,411,279,84,340,188
|
2555,340,740,2729,2,1577,1242,2190,1499,1277,277,2249,1671,1635,3217,436,2658,2900,2434,1910,1435,84,959,1555,1158,279,1440,925,2082,862,2084,2498,2301,1261,825,2584,1514,889,1,147,2935,966,2409,18,2839,2233,2234,44,1170,188,411,911
|
-0.5386155010309926,1.10136302234031,0.4339317726253653,-0.6219627517160322,5.203448495367863,-0.11532915716857117,0.05924575850806966,-0.3746072665047304,-0.07619722251063903,0.04003907639528579,1.2849471759441964,-0.39491714390968624,-0.15465833406450158,-0.13496893733397167,-1.0531559749508097,0.8790704925764257,-0.5801746865595289,-0.7062381065178011,-0.4766991906424338,-0.25386051882213734,-0.03726011192253851,2.599591402744298,0.23003816681518965,-0.09573868680970035,0.11658683691935393,1.2849471759441964,-0.03726011192253851,0.2674983597767239,-0.31399754246940065,0.32336109245226435,-0.31399754246940065,-0.4972821326535668,-0.4152809195710186,0.05924575850806966,0.36038744680166185,-0.5386155010309926,-0.07619722251063903,0.304783521666528,5.246740467606561,1.9821506505504098,-0.7274549681465066,0.23003816681518965,-0.4561715837491249,4.212879893636516,-0.663982825714329,-0.3746072665047304,-0.3746072665047304,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696
| 3,425
|
Establishment of protein localization to mitochondrial membrane
| 7
| 19
| 2.56464
| 0.010328
|
Q15070,Q8N8Q8,Q9Y584,O14737,Q9NS69,Q9Y5J9,Q9Y5J7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
520,272,44,234,18,411,188
|
2886,234,1380,1665,549,2732,520,2662,272,1117,18,1128,1888,761,44,1170,188,411,911
|
-0.7062381065178011,1.448448785568869,-0.017863872838918923,-0.15465833406450158,0.7039155427404739,-0.6219627517160322,0.7568551780007351,-0.5801746865595289,1.3014399603266282,0.13560845959237622,4.212879893636516,0.13560845959237622,-0.23391832955023042,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696
| 3,425
|
Transition metal ion transport
| 8
| 20
| 2.564242
| 0.01034
|
O15173,Q8N1S5,Q15043,P35670,Q9HD20,Q8NEW0,Q8N4V1,Q6NXT4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
229,327,335,307,244,314,186,348
|
229,1833,710,307,745,780,2699,1591,2254,335,1679,348,349,327,186,314,2673,1883,907,244
|
1.4807753146449134,-0.23391832955023042,0.4704535329188798,1.1853076769616102,0.4339317726253653,0.3972437030547652,-0.6010399151957811,-0.11532915716857117,-0.39491714390968624,1.1182193515975896,-0.15465833406450158,1.0844726591413512,1.0844726591413512,1.1350418152893942,1.7194151890935954,1.1685858128764244,-0.5801746865595289,-0.23391832955023042,0.2861626937330696,1.4159992226041558
| 3,425
|
Endopeptidase activity
| 32
| 65
| 2.561575
| 0.01042
|
Q92905,Q9BXS4,P67812,P49721,O75844,P28072,Q96RU2,P52888,Q13043,Q2T9J0,Q96K76,P60900,O43847,P28074,Q4J6C6,Q16740,Q99538,P55210,Q5JRX3,P20618,P28070,O14773,Q92542,Q10713,Q99436,Q99797,Q9BYT8,P07384,O43292,P42892,Q9NZ08,Q9UPU5
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
260,138,269,23,154,26,287,167,550,308,309,190,568,448,580,74,718,713,460,208,206,89,733,727,605,223,358,352,480,107,113,649
|
89,480,777,568,2890,154,352,2153,2003,3275,208,1063,2692,206,26,448,3131,2951,1587,2733,1756,107,2897,817,1353,23,167,876,2484,713,190,269,727,550,1723,2903,74,308,580,460,1290,882,1078,2580,2713,733,1048,260,2085,998,309,287,1930,605,718,223,2909,138,358,1123,113,649,760,2883,1621
|
2.5139509284160675,0.8094554736885617,0.3972437030547652,0.6684312487998063,-0.7062381065178011,1.9056938106121482,1.0675480922862204,-0.3543509374216771,-0.2938997945656019,-1.142484440376989,1.5610608196920086,0.15458450029912923,-0.6010399151957811,1.592965616941986,3.6839797644624737,0.8617217363584101,-0.9211596241735596,-0.7487318629297377,-0.11532915716857117,-0.6219627517160322,-0.19418721956236745,2.325553674617119,-0.7062381065178011,0.36038744680166185,0.001484545851543285,3.734421078054943,1.8285620188685285,0.304783521666528,-0.4972821326535668,0.4704535329188798,1.703709953072957,1.3014399603266282,0.4522133253996353,0.7039155427404739,-0.1743976571717926,-0.7062381065178011,2.7963313322340135,1.1853076769616102,0.6506311257033517,0.8443364414586735,0.04003907639528579,0.304783521666528,0.15458450029912923,-0.5386155010309926,-0.6010399151957811,0.4522133253996353,0.17351522707522676,1.3343293891978911,-0.31399754246940065,0.2112417984925894,1.1853076769616102,1.2518646944415734,-0.25386051882213734,0.6149138846414414,0.4704535329188798,1.5129799522193979,-0.7062381065178011,2.0730281075790966,1.0675480922862204,0.13560845959237622,2.281508618182512,0.5610423537706956,0.4339317726253653,-0.6850808626505676,-0.11532915716857117
| 3,425
|
Intrinsic component of golgi membrane
| 9
| 14
| 2.553171
| 0.010675
|
O95070,O43505,Q8TB61,O15155,L0R6Q1,P98194,Q5BJH7,Q6ZRP7,Q9Y282
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
413,104,109,776,738,780,247,631,24
|
738,776,1346,104,413,780,989,247,631,109,1079,24,1661,810
|
0.4339317726253653,0.3972437030547652,0.001484545851543285,2.340187200505293,0.9308994066578831,0.3972437030547652,0.2112417984925894,1.3997279417347968,0.5790392392161661,2.3108961338926965,0.15458450029912923,3.709233648956977,-0.13496893733397167,0.37883671691997084
| 3,425
|
Mitochondrial membrane organization
| 22
| 50
| 2.551902
| 0.010714
|
O95202,Q15070,Q8N8Q8,P45880,Q9NS69,Q9Y5J9,P49840,P30419,Q5XKP0,Q9Y584,Q8IWA4,Q9Y5J7,Q6UXV4,Q9NX63,Q9H3K2,Q13505,P52789,P12235,Q9BUR5,O60313,O14737,Q16611
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
382,520,272,14,18,411,667,549,561,44,433,188,696,195,720,73,725,469,621,482,234,629
|
2886,234,482,1172,1380,913,382,2805,949,1665,1424,469,3132,549,2732,3249,2483,14,667,779,725,73,520,629,820,959,2662,1596,561,696,433,1862,2218,272,1117,621,720,18,1653,195,1128,2094,1888,1621,761,44,1170,188,411,911
|
-0.7062381065178011,1.448448785568869,0.8094554736885617,0.09751936170847361,-0.017863872838918923,0.2674983597767239,0.999504346348033,-0.663982825714329,0.23003816681518965,-0.15465833406450158,-0.03726011192253851,0.8269144177911181,-0.9211596241735596,0.7039155427404739,-0.6219627517160322,-1.0976844720755563,-0.4972821326535668,4.496083243944842,0.5249283688242936,0.3972437030547652,0.4522133253996353,2.8379436574544386,0.7568551780007351,0.5790392392161661,0.36038744680166185,0.23003816681518965,-0.5801746865595289,-0.11532915716857117,0.6861926522306766,0.4886526246803302,0.8963828986355812,-0.23391832955023042,-0.3746072665047304,1.3014399603266282,0.13560845959237622,0.5969963442295187,0.4704535329188798,4.212879893636516,-0.13496893733397167,1.6879761304662688,0.13560845959237622,-0.31399754246940065,-0.23391832955023042,-0.11532915716857117,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696
| 3,425
|
Cation transmembrane transporter activity
| 29
| 81
| 2.541574
| 0.011035
|
O95202,Q70HW3,Q7KZN9,O43772,P24539,Q9UDW1,Q13423,P35670,O75964,Q8NEW0,Q8N4V1,P30825,Q8N1S5,P51790,Q15043,O00400,Q9Y619,Q93050,Q6NXT4,Q6PML9,P12235,P61421,P20674,Q9NQ11,Q96ES6,P20020,Q9HD20,P00846,Q9Y6M7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
382,133,529,143,547,48,560,307,56,314,186,571,327,204,335,86,221,473,348,349,469,600,353,101,231,235,244,121,390
|
86,931,143,813,1496,56,382,914,121,916,1533,949,1178,1704,2946,2151,1211,1753,469,762,1101,724,235,353,982,2104,547,2851,571,2326,307,839,1008,1841,1544,3204,204,1067,1249,1185,600,2900,780,1721,2203,560,335,1015,799,348,1291,349,133,529,327,186,1509,314,1975,473,964,231,1022,1735,1230,968,1299,1201,1883,907,1406,244,101,3406,48,1339,1056,634,1031,221,390
|
2.5425880302168293,0.24879026863223094,1.9973622966526008,0.36038744680166185,-0.07619722251063903,3.0567507737172264,0.999504346348033,0.2674983597767239,2.162978192726338,0.2674983597767239,-0.09573868680970035,0.23003816681518965,0.09751936170847361,-0.1743976571717926,-0.7487318629297377,-0.3543509374216771,0.0784057608191252,-0.19418721956236745,0.8269144177911181,0.41560864305026346,0.13560845959237622,0.4522133253996353,1.448448785568869,1.0675480922862204,0.2112417984925894,-0.3341478103334249,0.7039155427404739,-0.6850808626505676,0.6684312487998063,-0.43569894708233464,1.1853076769616102,0.34189565270391015,0.19240090545282404,-0.23391832955023042,-0.09573868680970035,-1.0309922696079223,1.6088736896093438,0.15458450029912923,0.05924575850806966,0.09751936170847361,0.6149138846414414,-0.7062381065178011,0.3972437030547652,-0.1743976571717926,-0.3746072665047304,0.6861926522306766,1.1182193515975896,0.19240090545282404,0.37883671691997084,1.0844726591413512,0.04003907639528579,1.0844726591413512,2.10311335779798,0.7392466032253644,1.1350418152893942,1.7194151890935954,-0.07619722251063903,1.1685858128764244,-0.27385423081555665,0.8269144177911181,0.23003816681518965,1.4807753146449134,0.19240090545282404,-0.1743976571717926,0.0784057608191252,0.23003816681518965,0.04003907639528579,0.09751936170847361,-0.23391832955023042,0.2861626937330696,-0.017863872838918923,1.4159992226041558,2.3839446526313073,-2.285109634377232,3.1642440468955613,0.020785433429236007,0.17351522707522676,0.5790392392161661,0.19240090545282404,1.5290369140825837,0.999504346348033
| 3,425
|
Mitochondrial respiratory chain complex assembly
| 24
| 51
| 2.512718
| 0.011981
|
P03915,Q15070,O96000,O95167,Q69YU5,Q8N8Q8,Q86Y39,Q7L592,Q9BSK2,O43676,O75306,O95831,Q9Y2R0,Q9NW81,Q6DKK2,Q96CU9,P03886,O95168,O43819,Q9Y6M9,Q9Y375,O43674,Q9BRT2,Q9H061
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
507,520,637,381,8,272,409,672,288,39,173,557,54,315,185,68,69,445,709,339,737,341,476,105
|
3408,341,39,1748,709,2186,173,1897,1175,1244,381,445,1382,2478,557,637,69,507,3344,1544,2385,2067,2022,520,2535,8,185,672,409,884,3156,1440,272,2132,68,999,476,288,2366,105,2756,315,1300,2309,1128,2178,1888,54,737,761,339
|
-2.4725910422416124,1.10136302234031,3.33632142390138,-0.19418721956236745,0.4704535329188798,-0.3746072665047304,1.7975170034836079,-0.25386051882213734,0.09751936170847361,0.05924575850806966,0.999504346348033,0.8617217363584101,-0.017863872838918923,-0.4972821326535668,0.6861926522306766,0.5610423537706956,2.8655806296701516,0.7744260494954054,-1.3707038556261375,-0.09573868680970035,-0.4561715837491249,-0.31399754246940065,-0.2938997945656019,0.7568551780007351,-0.5179207785497725,4.669065000725359,1.7194151890935954,0.5249283688242936,0.9481038780076505,0.304783521666528,-0.9429962985415629,-0.03726011192253851,1.3014399603266282,-0.3341478103334249,2.879367974649712,0.2112417984925894,0.8269144177911181,1.2518646944415734,-0.43569894708233464,2.340187200505293,-0.6219627517160322,1.1685858128764244,0.04003907639528579,-0.4152809195710186,0.13560845959237622,-0.3543509374216771,-0.23391832955023042,3.097206606706352,0.4522133253996353,0.4339317726253653,1.1182193515975896
| 3,425
|
Protein localization to vacuole
| 8
| 23
| 2.50997
| 0.012074
|
P60033,Q9NQ11,P46934,Q14108,Q9NUN5,P20645,Q9NQC3,Q92783
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
292,101,423,13,145,457,210,280
|
2886,2600,1137,1835,795,457,423,2610,292,13,1260,280,1000,686,2225,1404,1447,101,210,145,1167,587,1657
|
-0.7062381065178011,-0.5593666767876478,0.11658683691935393,-0.23391832955023042,0.37883671691997084,0.8443364414586735,0.9136591415130947,-0.5593666767876478,1.2352746846067904,4.530920591223999,0.05924575850806966,1.2849471759441964,0.2112417984925894,0.5068108281574367,-0.3746072665047304,-0.017863872838918923,-0.03726011192253851,2.3839446526313073,1.5610608196920086,1.9973622966526008,0.11658683691935393,0.6506311257033517,-0.13496893733397167
| 3,425
|
Lipid transporter activity
| 13
| 23
| 2.505511
| 0.012227
|
P33527,O15118,Q9BZF1,Q9BZF3,P17900,P08183,Q96GC9,P30536,Q96SU4,Q9NZD2,Q96AA3,P48739,Q9Y5P4
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
666,97,261,757,166,322,676,242,703,736,152,743,544
|
1746,97,2514,322,1274,166,2284,871,242,666,743,1218,799,1814,152,676,703,1933,261,757,2040,736,544
|
-0.19418721956236745,2.3984830795821077,-0.5179207785497725,1.1350418152893942,0.04003907639528579,1.8285620188685285,-0.4152809195710186,0.304783521666528,1.4159992226041558,0.5249283688242936,0.4339317726253653,0.0784057608191252,0.37883671691997084,-0.21402733728023318,1.9210387080998343,0.5249283688242936,0.4886526246803302,-0.25386051882213734,1.3343293891978911,0.4339317726253653,-0.2938997945656019,0.4522133253996353,0.7216001253197305
| 3,425
|
Intracellular protein transmembrane transport
| 6
| 22
| 2.484106
| 0.012988
|
Q99595,O60830,Q15629,O14925,O75298,Q9UGP8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,2,84,340,403,389
|
340,740,2,403,1577,1380,557,1457,3182,653,2658,2570,2900,416,84,959,1440,825,1514,1,2368,389
|
1.10136302234031,0.4339317726253653,5.203448495367863,0.9481038780076505,-0.11532915716857117,-0.017863872838918923,0.6861926522306766,-0.056704463496115395,-1.00889493373649,0.5430054701796704,-0.5801746865595289,-0.5386155010309926,-0.7062381065178011,0.9308994066578831,2.599591402744298,0.23003816681518965,-0.03726011192253851,0.36038744680166185,-0.07619722251063903,5.246740467606561,-0.43569894708233464,0.999504346348033
| 3,425
|
Abnormality of head blood vessel
| 6
| 26
| 2.477423
| 0.013234
|
P03886,P16278,P07602,Q13510,P10619,P00846
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
69,10,77,17,114,121
|
2512,1891,2682,1830,121,69,507,384,77,1750,114,2690,10,166,414,2286,3392,2811,2858,17,1190,1441,2134,552,2411,679
|
-0.5179207785497725,-0.25386051882213734,-0.6010399151957811,-0.23391832955023042,2.162978192726338,2.8655806296701516,0.7744260494954054,0.999504346348033,2.7125341584739417,-0.19418721956236745,2.2667784467407786,-0.6010399151957811,4.600231735570217,1.8285620188685285,0.9308994066578831,-0.4152809195710186,-1.8501181590001228,-0.663982825714329,-0.6850808626505676,4.3200361894985715,0.09751936170847361,-0.03726011192253851,-0.3341478103334249,0.7039155427404739,-0.4561715837491249,0.5249283688242936
| 3,425
|
Outer mitochondrial membrane protein complex
| 9
| 17
| 2.47697
| 0.01325
|
Q6UXV4,Q9NX63,Q9BUR5,Q13505,Q5XKP0,Q8IWA4,Q9NS69,Q8N4H5,Q15388
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
696,195,621,73,561,433,18,150,416
|
1172,1380,1457,3249,73,416,820,1596,561,696,433,150,621,18,1653,195,761
|
0.09751936170847361,-0.017863872838918923,-0.056704463496115395,-1.0976844720755563,2.8379436574544386,0.9308994066578831,0.36038744680166185,-0.11532915716857117,0.6861926522306766,0.4886526246803302,0.8963828986355812,1.95164797870373,0.5969963442295187,4.212879893636516,-0.13496893733397167,1.6879761304662688,0.4339317726253653
| 3,425
|
Glycosyltransferase
| 10
| 41
| 2.473355
| 0.013385
|
Q8N4A0,O43505,Q9BT22,Q13126,Q10472,P04062,P43490,Q8NAT1,Q9NP73,Q06203
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
328,104,361,11,270,80,112,368,376,405
|
1171,104,2684,1061,1703,1310,80,1628,2058,2891,2280,2767,1950,1668,112,1711,2527,405,989,270,11,1076,630,438,995,328,368,562,2746,1561,783,1162,361,1516,832,1936,376,2308,2508,1205,1574
|
0.09751936170847361,2.340187200505293,-0.6010399151957811,0.15458450029912923,-0.1743976571717926,0.020785433429236007,2.62795906725318,-0.13496893733397167,-0.31399754246940065,-0.7062381065178011,-0.4152809195710186,-0.6429435893726733,-0.27385423081555665,-0.15465833406450158,2.281508618182512,-0.1743976571717926,-0.5179207785497725,0.9481038780076505,0.2112417984925894,1.3014399603266282,4.577181521435861,0.15458450029912923,0.5790392392161661,0.8790704925764257,0.2112417984925894,1.1350418152893942,1.0335956619699211,0.6861926522306766,-0.6219627517160322,-0.09573868680970035,0.3972437030547652,0.11658683691935393,1.0505891507074792,-0.07619722251063903,0.36038744680166185,-0.25386051882213734,1.0165674522554908,-0.4152809195710186,-0.4972821326535668,0.09751936170847361,-0.09573868680970035
| 3,425
|
Hepatomegaly
| 57
| 183
| 2.460801
| 0.013863
|
P03915,O95235,O96000,P16278,Q9UJW0,Q14108,O43772,Q13510,P00374,P49327,Q86Y39,Q96AA3,Q14739,O75845,Q9NZJ7,Q13043,P60033,O43676,P23786,P40855,P10253,O75306,Q16134,Q15904,P00813,P35670,Q96A33,Q9UJS0,Q9NWS8,Q96CU9,P50416,P03886,Q01844,P04066,P54802,P07602,P14174,P28070,P04062,Q96AX1,Q9NPL8,Q9Y6M9,O75787,Q9Y619,P15586,O15118,P20674,P09601,Q9BUB7,Q6NUQ1,Q9BT22,Q15067,Q13426,Q9NP73,P00846,Q9UGP8,Q9NVI7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
507,383,637,10,266,13,143,17,19,526,409,152,281,162,552,550,292,39,170,422,421,173,304,177,180,307,441,586,584,68,449,69,578,576,202,77,333,206,80,209,465,339,590,221,345,97,353,102,620,354,361,386,614,376,121,389,647
|
2886,3408,1745,2761,2600,97,39,143,1061,2889,2186,173,2477,1576,1577,1172,1897,1139,590,1702,162,1175,913,383,1899,637,1900,19,180,121,1901,69,507,80,576,3420,1210,1628,3161,77,1750,2605,102,2001,421,1274,3380,3419,2282,3229,333,2892,2422,345,10,2948,2770,353,3054,982,3130,170,3150,3174,206,871,3344,1065,3081,653,1632,1429,1755,1668,1540,307,3201,2195,3056,3202,3289,422,2332,3203,526,2693,2565,3334,449,2566,2198,1674,3296,2980,202,2774,2067,920,292,2570,1218,2250,2813,2737,1638,1282,578,2116,1912,3166,1147,727,550,614,17,2781,13,2702,281,386,2163,177,304,749,2708,2122,1813,354,993,2448,1725,3035,409,884,3156,2581,2132,2625,2787,1772,441,152,209,2402,68,1080,1977,999,826,1000,2545,829,1688,361,620,1299,1371,907,1406,376,465,1333,647,3346,584,1300,2091,552,2309,1885,389,586,266,1167,1058,1377,1697,737,2180,2236,3047,221,339
|
-0.7062381065178011,-2.4725910422416124,-0.19418721956236745,-0.6429435893726733,-0.5593666767876478,2.3984830795821077,3.33632142390138,1.9973622966526008,0.15458450029912923,-0.7062381065178011,-0.3746072665047304,1.7975170034836079,-0.4972821326535668,-0.11532915716857117,-0.11532915716857117,0.09751936170847361,-0.25386051882213734,0.11658683691935393,0.6327920744221581,-0.1743976571717926,1.844043079409893,0.09751936170847361,0.2674983597767239,0.999504346348033,-0.25386051882213734,0.5610423537706956,-0.25386051882213734,4.12871911169829,1.7663606487132952,2.162978192726338,-0.25386051882213734,2.8655806296701516,0.7744260494954054,2.62795906725318,0.6506311257033517,-4.614574746442564,0.0784057608191252,-0.13496893733397167,-0.9648974270030561,2.7125341584739417,-0.19418721956236745,-0.5593666767876478,2.3693825937809168,-0.2938997945656019,0.9136591415130947,0.04003907639528579,-1.678616982119575,-4.388908904715628,-0.4152809195710186,-1.075386542805351,1.1182193515975896,-0.7062381065178011,-0.4766991906424338,1.0844726591413512,4.600231735570217,-0.7487318629297377,-0.6429435893726733,1.0675480922862204,-0.8344482451084184,0.2112417984925894,-0.9211596241735596,1.813053367361717,-0.9429962985415629,-0.9868634800659423,1.592965616941986,0.304783521666528,-1.3707038556261375,0.15458450029912923,-0.8560317012161593,0.5430054701796704,-0.13496893733397167,-0.03726011192253851,-0.19418721956236745,-0.15465833406450158,-0.09573868680970035,1.1853076769616102,-1.0309922696079223,-0.3746072665047304,-0.8344482451084184,-1.0309922696079223,-1.1649875074107834,0.9136591415130947,-0.43569894708233464,-1.0309922696079223,0.7392466032253644,-0.6010399151957811,-0.5386155010309926,-1.32448279287036,0.8617217363584101,-0.5386155010309926,-0.3746072665047304,-0.15465833406450158,-1.1875599920679472,-0.7700692108929594,1.6247523908291193,-0.6429435893726733,-0.31399754246940065,0.2674983597767239,1.2352746846067904,-0.5386155010309926,0.0784057608191252,-0.39491714390968624,-0.663982825714329,-0.6219627517160322,-0.13496893733397167,0.04003907639528579,0.6506311257033517,-0.3341478103334249,-0.25386051882213734,-0.9648974270030561,0.11658683691935393,0.4522133253996353,0.7039155427404739,0.5969963442295187,4.3200361894985715,-0.6429435893726733,4.530920591223999,-0.6010399151957811,1.268422139234549,0.999504346348033,-0.3543509374216771,1.7819528049746483,1.2019963358891592,0.4339317726253653,-0.6010399151957811,-0.3341478103334249,-0.21402733728023318,1.0675480922862204,0.2112417984925894,-0.4766991906424338,-0.1743976571717926,-0.8129269700518783,0.9481038780076505,0.304783521666528,-0.9429962985415629,-0.5386155010309926,-0.3341478103334249,-0.5593666767876478,-0.6429435893726733,-0.19418721956236745,0.8790704925764257,1.9210387080998343,1.5610608196920086,-0.4561715837491249,2.879367974649712,0.15458450029912923,-0.27385423081555665,0.2112417984925894,0.36038744680166185,0.2112417984925894,-0.5179207785497725,0.36038744680166185,-0.15465833406450158,1.0505891507074792,0.5969963442295187,0.04003907639528579,0.001484545851543285,0.2861626937330696,-0.017863872838918923,1.0165674522554908,0.8443364414586735,0.020785433429236007,0.5610423537706956,-1.3707038556261375,0.6506311257033517,0.04003907639528579,-0.31399754246940065,0.7039155427404739,-0.4152809195710186,-0.23391832955023042,0.999504346348033,0.6506311257033517,1.3179006469481906,0.11658683691935393,0.17351522707522676,0.001484545851543285,-0.15465833406450158,0.4522133253996353,-0.3543509374216771,-0.3746072665047304,-0.8129269700518783,1.5290369140825837,1.1182193515975896
| 3,425
|
Juvenile onset
| 14
| 44
| 2.449951
| 0.014288
|
Q9UI10,Q14566,O15118,P07196,Q9NQ11,P16278,P06280,P54802,P49770,Q13510,P41440,O14773,P57740,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
493,519,97,447,101,10,139,202,346,17,458,89,436,29
|
89,97,1833,2994,1901,1582,139,1312,447,10,2850,2107,2429,3289,857,458,2015,346,3349,517,745,3188,202,436,1504,1467,2489,17,2207,519,1916,1473,1475,2498,3240,783,1299,2673,3225,101,1126,29,493,1660
|
2.5139509284160675,2.3984830795821077,-0.23391832955023042,-0.79146743676524,-0.25386051882213734,-0.11532915716857117,2.057946899190213,0.020785433429236007,0.8617217363584101,4.600231735570217,-0.6850808626505676,-0.3341478103334249,-0.4766991906424338,-1.1649875074107834,0.32336109245226435,0.8443364414586735,-0.2938997945656019,1.0844726591413512,-1.3939257358204213,0.7568551780007351,0.4339317726253653,-1.00889493373649,1.6247523908291193,0.8790704925764257,-0.07619722251063903,-0.056704463496115395,-0.4972821326535668,4.3200361894985715,-0.3746072665047304,0.7568551780007351,-0.25386051882213734,-0.056704463496115395,-0.056704463496115395,-0.4972821326535668,-1.075386542805351,0.3972437030547652,0.04003907639528579,-0.5801746865595289,-1.0531559749508097,2.3839446526313073,0.13560845959237622,3.59506153369759,0.8094554736885617,-0.13496893733397167
| 3,425
|
FAD/NAD(P)-binding domain superfamily [IPR036188]
| 7
| 21
| 2.445559
| 0.014463
|
Q8NB78,Q9UHG3,Q96CU9,Q8NCN5,Q16134,Q8NBM8,Q6NUM9
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
32,4,68,237,304,146,256
|
2973,557,2803,2001,3232,2518,2325,1278,818,1633,407,304,2930,256,32,146,237,68,597,1652,4
|
-0.7700692108929594,0.6861926522306766,-0.663982825714329,-0.2938997945656019,-1.075386542805351,-0.5179207785497725,-0.43569894708233464,0.04003907639528579,0.36038744680166185,-0.13496893733397167,0.9481038780076505,1.2019963358891592,-0.7274549681465066,1.3507263392996962,3.4276882240821887,1.9821506505504098,1.448448785568869,2.879367974649712,0.6327920744221581,-0.13496893733397167,5.094411977540183
| 3,425
|
Inorganic anion transmembrane transporter activity
| 8
| 21
| 2.435105
| 0.014887
|
Q9C0H2,P21796,P51790,P45880,Q15043,Q9UBX3,Q9Y277,O43681
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
70,5,204,14,335,111,220,311
|
2315,2514,311,2923,5,666,14,204,1067,1550,335,799,3394,3256,803,968,70,111,220,3333,390
|
-0.43569894708233464,-0.5179207785497725,1.1685858128764244,-0.7274549681465066,4.917492659435559,0.5249283688242936,4.496083243944842,1.6088736896093438,0.15458450029912923,-0.09573868680970035,1.1182193515975896,0.37883671691997084,-1.8749638166066318,-1.0976844720755563,0.37883671691997084,0.23003816681518965,2.8655806296701516,2.2962144810512832,1.5290369140825837,-1.3014824482535676,0.999504346348033
| 3,425
|
Calcium-binding protein
| 7
| 19
| 2.433469
| 0.014955
|
O43852,Q14257,P80303,P43307,Q9BRK5,Q02818,P41208
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
380,168,6,40,370,51,277
|
380,3174,1754,277,40,858,6,51,168,2162,2963,3167,426,3125,2135,595,1403,370,809
|
0.999504346348033,-0.9868634800659423,-0.19418721956236745,1.2849471759441964,3.296890926305054,0.32336109245226435,4.895159421570552,3.137486998744578,1.8285620188685285,-0.3543509374216771,-0.7487318629297377,-0.9648974270030561,0.9136591415130947,-0.8993869388026995,-0.3341478103334249,0.6327920744221581,-0.017863872838918923,1.0335956619699211,0.37883671691997084
| 3,425
|
Intrinsic component of endoplasmic reticulum membrane
| 25
| 65
| 2.427737
| 0.015193
|
P10321,Q9Y4P3,Q9Y282,Q15125,O75298,O75844,P30511,Q8NBI6,P49069,Q96A33,Q8N4V1,Q6Y1H2,Q9P035,Q86XL3,Q9NQC3,Q15629,Q86YN1,Q9UKV5,Q9NZ01,Q15041,Q9GZP9,O43292,Q03519,Q8TB61,O95470
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
396,679,24,151,403,154,28,562,431,441,186,697,585,78,210,84,212,610,94,601,227,480,236,109,118
|
1489,1006,1746,480,812,403,154,691,894,118,2804,1311,396,3174,2246,2951,28,431,1247,877,2900,1640,236,1110,2075,748,601,151,84,2077,821,882,697,1726,78,212,186,1771,562,109,2713,1048,1924,1079,441,829,1514,1931,1083,2937,227,2588,2142,1372,210,94,585,3089,2839,972,610,1056,24,679,975
|
-0.07619722251063903,0.19240090545282404,-0.19418721956236745,0.8094554736885617,0.36038744680166185,0.9481038780076505,1.9056938106121482,0.4886526246803302,0.2861626937330696,2.2224410858737813,-0.663982825714329,0.020785433429236007,0.9652727380057537,-0.9868634800659423,-0.39491714390968624,-0.7487318629297377,3.6205514552672318,0.8963828986355812,0.05924575850806966,0.304783521666528,-0.7062381065178011,-0.13496893733397167,1.448448785568869,0.13560845959237622,-0.31399754246940065,0.4339317726253653,0.6149138846414414,1.9210387080998343,2.599591402744298,-0.31399754246940065,0.36038744680166185,0.304783521666528,0.4886526246803302,-0.1743976571717926,2.6703449638891956,1.5450638238651857,1.7194151890935954,-0.19418721956236745,0.6861926522306766,2.3108961338926965,-0.6010399151957811,0.17351522707522676,-0.25386051882213734,0.15458450029912923,0.8790704925764257,0.36038744680166185,-0.07619722251063903,-0.25386051882213734,0.15458450029912923,-0.7274549681465066,1.4968927991314636,-0.5386155010309926,-0.3341478103334249,0.001484545851543285,1.5610608196920086,2.4564023437522535,0.6506311257033517,-0.8560317012161593,-0.663982825714329,0.23003816681518965,0.6149138846414414,0.17351522707522676,3.709233648956977,0.5249283688242936,0.23003816681518965
| 3,425
|
Inner mitochondrial membrane organization
| 11
| 24
| 2.422994
| 0.015393
|
Q6UXV4,Q9NX63,O95202,Q9BUR5,Q9H3K2,Q13505,Q5XKP0,Q9Y584,O60313,Q9Y5J9,Q9Y5J7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
696,195,382,621,720,73,561,44,482,411,188
|
482,1172,1380,382,3249,73,820,2662,1596,561,696,1117,621,720,1653,195,1128,1621,761,44,1170,188,411,911
|
0.8094554736885617,0.09751936170847361,-0.017863872838918923,0.999504346348033,-1.0976844720755563,2.8379436574544386,0.36038744680166185,-0.5801746865595289,-0.11532915716857117,0.6861926522306766,0.4886526246803302,0.13560845959237622,0.5969963442295187,0.4704535329188798,-0.13496893733397167,1.6879761304662688,0.13560845959237622,-0.11532915716857117,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696
| 3,425
|
Sphingolipid de novo biosynthesis
| 7
| 13
| 2.422781
| 0.015402
|
Q96G23,O15269,P51648,Q06136,O95470,P27544,Q9NRA0
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
103,172,141,527,118,125,290
|
172,1095,2845,118,2284,125,141,527,1597,103,290,2369,544
|
1.7975170034836079,0.13560845959237622,-0.6850808626505676,2.2224410858737813,-0.4152809195710186,2.133096436106864,2.027706771884764,0.7392466032253644,-0.11532915716857117,2.3693825937809168,1.2518646944415734,-0.43569894708233464,0.7216001253197305
| 3,425
|
Cellular transition metal ion homeostasis
| 8
| 23
| 2.41477
| 0.015745
|
Q9NQ11,P09601,P05067,Q15043,Q15904,P35670,Q8N511,Q8NEW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
101,102,297,335,177,307,53,314
|
2886,2600,709,852,1833,1175,3159,710,297,102,1536,873,307,1841,600,335,177,349,53,314,2673,101,634
|
-0.7062381065178011,-0.5593666767876478,0.4704535329188798,0.32336109245226435,-0.23391832955023042,0.09751936170847361,-0.9648974270030561,0.4704535329188798,1.2186519515565648,2.3693825937809168,-0.09573868680970035,0.304783521666528,1.1853076769616102,-0.23391832955023042,0.6149138846414414,1.1182193515975896,1.7819528049746483,1.0844726591413512,3.1106528049037374,1.1685858128764244,-0.5801746865595289,2.3839446526313073,0.5790392392161661
| 3,425
|
Carboxylic acid transport
| 13
| 33
| 2.414395
| 0.015761
|
Q9UJS0,Q9NZJ7,P07602,P14174,Q9UBX3,Q9BQT8,P53985,P41440,Q9Y619,O60831,P30825,Q9H2D1,Q15041
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
586,552,77,333,111,305,591,458,221,402,571,157,601
|
1528,2514,402,1140,2150,778,2320,77,2151,333,871,571,666,458,1674,591,1067,1550,1250,601,1015,1814,3256,1022,1735,305,157,1201,1883,552,111,586,221
|
-0.09573868680970035,-0.5179207785497725,0.9481038780076505,0.11658683691935393,-0.3543509374216771,0.3972437030547652,-0.43569894708233464,2.7125341584739417,-0.3543509374216771,1.1182193515975896,0.304783521666528,0.6684312487998063,0.5249283688242936,0.8443364414586735,-0.15465833406450158,0.6327920744221581,0.15458450029912923,-0.09573868680970035,0.05924575850806966,0.6149138846414414,0.19240090545282404,-0.21402733728023318,-1.0976844720755563,0.19240090545282404,-0.1743976571717926,1.2019963358891592,1.9056938106121482,0.09751936170847361,-0.23391832955023042,0.7039155427404739,2.2962144810512832,0.6506311257033517,1.5290369140825837
| 3,425
|
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
| 6
| 29
| 2.412573
| 0.01584
|
Q96RQ1,P24390,Q12907,P49755,Q9Y282,Q9P2W9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,12,334,343,24,153
|
1991,946,1346,2417,1498,570,12,1351,1905,743,343,2898,2157,2737,988,683,334,1110,354,1866,1867,1079,129,596,1371,2463,153,2232,24
|
-0.2938997945656019,0.23003816681518965,0.001484545851543285,-0.4766991906424338,-0.07619722251063903,0.6684312487998063,4.5656364088713355,0.001484545851543285,-0.25386051882213734,0.4339317726253653,1.10136302234031,-0.7062381065178011,-0.3543509374216771,-0.6219627517160322,0.2112417984925894,0.5068108281574367,1.1182193515975896,0.13560845959237622,1.0675480922862204,-0.23391832955023042,-0.23391832955023042,0.15458450029912923,2.118117615036976,0.6327920744221581,0.001484545851543285,-0.4766991906424338,1.9210387080998343,-0.3746072665047304,3.709233648956977
| 3,425
|
Transition metal ion homeostasis
| 9
| 27
| 2.411198
| 0.0159
|
Q9NQ11,P09601,P05067,Q15043,Q15904,P35670,Q8N511,P30519,Q8NEW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
101,102,297,335,177,307,53,21,314
|
2886,2600,709,852,1833,1175,3159,710,3362,297,102,1536,21,873,307,1841,600,1638,2780,335,177,349,53,314,2673,101,634
|
-0.7062381065178011,-0.5593666767876478,0.4704535329188798,0.32336109245226435,-0.23391832955023042,0.09751936170847361,-0.9648974270030561,0.4704535329188798,-1.5111725380859105,1.2186519515565648,2.3693825937809168,-0.09573868680970035,3.921251120524279,0.304783521666528,1.1853076769616102,-0.23391832955023042,0.6149138846414414,-0.13496893733397167,-0.6429435893726733,1.1182193515975896,1.7819528049746483,1.0844726591413512,3.1106528049037374,1.1685858128764244,-0.5801746865595289,2.3839446526313073,0.5790392392161661
| 3,425
|
Ion channel transport
| 17
| 30
| 2.406564
| 0.016103
|
P61421,Q4KMQ2,Q9C0H2,Q9NQ11,P51790,P20020,P30626,Q15904,Q5EBL8,P35670,P98194,Q99576,Q9Y487,Q9HD20,Q93050,Q96PU5,P16615
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
600,799,70,101,204,235,873,177,459,307,780,926,634,244,473,417,724
|
916,1533,724,235,982,2104,1103,873,307,1008,1841,204,2657,600,780,2024,3102,177,799,459,473,417,926,70,1820,244,101,1339,634,1031
|
0.2674983597767239,-0.09573868680970035,0.4522133253996353,1.448448785568869,0.2112417984925894,-0.3341478103334249,0.13560845959237622,0.304783521666528,1.1853076769616102,0.19240090545282404,-0.23391832955023042,1.6088736896093438,-0.5801746865595289,0.6149138846414414,0.3972437030547652,-0.2938997945656019,-0.8776777826591424,1.7819528049746483,0.37883671691997084,0.8443364414586735,0.8269144177911181,0.9308994066578831,0.2674983597767239,2.8655806296701516,-0.21402733728023318,1.4159992226041558,2.3839446526313073,0.020785433429236007,0.5790392392161661,0.19240090545282404
| 3,425
|
Rhizomelia
| 6
| 12
| 2.397935
| 0.016488
|
Q9Y366,Q15392,Q14739,O00116,Q03164,Q15125
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
321,36,281,199,211,151
|
199,2238,3145,412,1181,1905,211,281,151,36,972,321
|
1.6564222106812256,-0.39491714390968624,-0.9429962985415629,0.9308994066578831,0.09751936170847361,-0.25386051882213734,1.5450638238651857,1.268422139234549,1.9210387080998343,3.3886394720355844,0.23003816681518965,1.1518305804680873
| 3,425
|
Hand polydactyly
| 16
| 36
| 2.395592
| 0.016594
|
P21964,O43924,O96028,O95202,Q15125,O75845,Q9BXW9,Q15067,Q9UHX1,Q12768,O75665,Q14739,Q13045,Q96J42,Q9Y263,P98175
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
414,130,131,382,151,162,428,386,401,498,342,281,312,126,418,535
|
2512,3094,130,852,342,162,382,131,3304,414,2429,2811,2696,535,727,498,312,2958,281,2865,386,151,551,1475,996,2134,3127,126,1445,428,2791,972,401,1056,1826,418
|
-0.5179207785497725,-0.8776777826591424,2.10311335779798,0.32336109245226435,1.10136302234031,1.844043079409893,0.999504346348033,2.10311335779798,-1.2102024240548812,0.9308994066578831,-0.4766991906424338,-0.663982825714329,-0.6010399151957811,0.7216001253197305,0.4522133253996353,0.7919594158846363,1.1685858128764244,-0.7487318629297377,1.268422139234549,-0.6850808626505676,0.999504346348033,1.9210387080998343,0.7039155427404739,-0.056704463496115395,0.2112417984925894,-0.3341478103334249,-0.8993869388026995,2.133096436106864,-0.03726011192253851,0.9136591415130947,-0.6429435893726733,0.23003816681518965,0.9652727380057537,0.17351522707522676,-0.21402733728023318,0.9308994066578831
| 3,425
|
Sterol biosynthetic process
| 8
| 28
| 2.394533
| 0.016642
|
O75845,Q15125,Q15392,Q15800,Q16850,Q14534,Q14739,P16435
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
162,151,36,43,46,407,281,435
|
980,162,894,1898,3198,494,1038,435,1009,2483,1500,2066,1039,2927,2116,1250,2575,407,281,151,2346,36,1915,43,46,972,2370,1088
|
0.2112417984925894,1.844043079409893,0.2861626937330696,-0.25386051882213734,-1.0309922696079223,0.7919594158846363,0.17351522707522676,0.8790704925764257,0.19240090545282404,-0.4972821326535668,-0.07619722251063903,-0.31399754246940065,0.17351522707522676,-0.7274549681465066,-0.3341478103334249,0.05924575850806966,-0.5386155010309926,0.9481038780076505,1.268422139234549,1.9210387080998343,-0.43569894708233464,3.3886394720355844,-0.25386051882213734,3.2440577254623797,3.1775938115320623,0.23003816681518965,-0.43569894708233464,0.15458450029912923
| 3,425
|
Proteasome core complex
| 7
| 15
| 2.393022
| 0.01671
|
P28074,Q92530,P28070,P20618,P49721,P28072,P60900
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
448,490,206,208,23,26,190
|
2681,208,2383,1348,1064,2692,2425,206,26,448,1353,23,190,490,605
|
-0.6010399151957811,1.5610608196920086,-0.4561715837491249,0.001484545851543285,0.15458450029912923,-0.6010399151957811,-0.4766991906424338,1.592965616941986,3.6839797644624737,0.8617217363584101,0.001484545851543285,3.734421078054943,1.703709953072957,0.8094554736885617,0.6149138846414414
| 3,425
|
Inorganic molecular entity transmembrane transporter activity
| 29
| 87
| 2.386807
| 0.016995
|
O95202,P21796,Q7KZN9,P45880,P24539,Q9UDW1,P36383,P35670,O75964,Q8N4V1,O43681,Q9C0H2,Q8N1S5,P51790,Q15043,O00400,Q9Y277,Q93050,Q6NXT4,P12235,Q99797,P20674,Q9NQ11,Q96ES6,P20020,Q9UBX3,Q9HD20,P00846,Q9Y6M7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
382,5,529,14,547,48,430,307,56,186,311,70,327,204,335,86,220,473,348,469,223,353,101,231,235,111,244,121,390
|
2315,86,931,2514,311,1496,56,382,914,121,916,1533,949,1178,1704,2946,2151,1211,2923,1753,469,762,1101,724,235,353,982,2104,5,547,2851,2326,666,307,430,839,1008,1841,14,1544,3204,204,1067,1249,1185,600,2900,780,1721,2203,1550,560,335,799,3394,348,1291,529,3256,327,186,1509,1975,473,964,231,1735,803,223,968,70,1299,1201,907,244,101,3406,834,111,48,1339,1056,220,634,1031,3333,390
|
-0.43569894708233464,2.5425880302168293,0.24879026863223094,-0.5179207785497725,1.1685858128764244,-0.07619722251063903,3.0567507737172264,0.999504346348033,0.2674983597767239,2.162978192726338,0.2674983597767239,-0.09573868680970035,0.23003816681518965,0.09751936170847361,-0.1743976571717926,-0.7487318629297377,-0.3543509374216771,0.0784057608191252,-0.7274549681465066,-0.19418721956236745,0.8269144177911181,0.41560864305026346,0.13560845959237622,0.4522133253996353,1.448448785568869,1.0675480922862204,0.2112417984925894,-0.3341478103334249,4.917492659435559,0.7039155427404739,-0.6850808626505676,-0.43569894708233464,0.5249283688242936,1.1853076769616102,0.8963828986355812,0.34189565270391015,0.19240090545282404,-0.23391832955023042,4.496083243944842,-0.09573868680970035,-1.0309922696079223,1.6088736896093438,0.15458450029912923,0.05924575850806966,0.09751936170847361,0.6149138846414414,-0.7062381065178011,0.3972437030547652,-0.1743976571717926,-0.3746072665047304,-0.09573868680970035,0.6861926522306766,1.1182193515975896,0.37883671691997084,-1.8749638166066318,1.0844726591413512,0.04003907639528579,0.7392466032253644,-1.0976844720755563,1.1350418152893942,1.7194151890935954,-0.07619722251063903,-0.27385423081555665,0.8269144177911181,0.23003816681518965,1.4807753146449134,-0.1743976571717926,0.37883671691997084,1.5129799522193979,0.23003816681518965,2.8655806296701516,0.04003907639528579,0.09751936170847361,0.2861626937330696,1.4159992226041558,2.3839446526313073,-2.285109634377232,0.36038744680166185,2.2962144810512832,3.1642440468955613,0.020785433429236007,0.17351522707522676,1.5290369140825837,0.5790392392161661,0.19240090545282404,-1.3014824482535676,0.999504346348033
| 3,425
|
Sphingolipid pathway
| 7
| 10
| 2.386551
| 0.017007
|
Q96G23,O15269,P04062,Q13510,Q06136,O95470,Q9NRA0
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
103,172,80,17,527,118,290
|
172,1095,118,80,3060,527,17,103,290,544
|
1.7975170034836079,0.13560845959237622,2.2224410858737813,2.62795906725318,-0.8344482451084184,0.7392466032253644,4.3200361894985715,2.3693825937809168,1.2518646944415734,0.7216001253197305
| 3,425
|
Hexosyltransferase activity
| 9
| 39
| 2.377339
| 0.017438
|
Q8N4A0,O43505,Q9BT22,Q13126,Q10472,P04062,Q8NAT1,Q9NP73,P06865
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
328,104,361,11,270,80,368,376,384
|
2513,1171,104,2684,1061,2477,80,1532,2378,1628,384,1750,2767,1950,1668,2014,1711,2253,2527,989,270,11,1076,715,995,328,368,2746,1561,783,1162,361,832,1936,376,2308,442,1205,1574
|
-0.5179207785497725,0.09751936170847361,2.340187200505293,-0.6010399151957811,0.15458450029912923,-0.4972821326535668,2.62795906725318,-0.09573868680970035,-0.4561715837491249,-0.13496893733397167,0.999504346348033,-0.19418721956236745,-0.6429435893726733,-0.27385423081555665,-0.15465833406450158,-0.2938997945656019,-0.1743976571717926,-0.39491714390968624,-0.5179207785497725,0.2112417984925894,1.3014399603266282,4.577181521435861,0.15458450029912923,0.4704535329188798,0.2112417984925894,1.1350418152893942,1.0335956619699211,-0.6219627517160322,-0.09573868680970035,0.3972437030547652,0.11658683691935393,1.0505891507074792,0.36038744680166185,-0.25386051882213734,1.0165674522554908,-0.4152809195710186,0.8790704925764257,0.09751936170847361,-0.09573868680970035
| 3,425
|
Protein targeting to membrane
| 9
| 37
| 2.375761
| 0.017513
|
O00560,P43307,Q9UHB9,Q15629,Q5BJH7,O60725,O43681,Q9UGP8,P46379
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
419,40,52,84,247,88,311,389,63
|
2555,419,311,1994,88,3212,3077,1103,2325,653,2011,422,40,63,1758,920,2658,2570,2900,2203,1505,601,84,247,2355,1972,2829,1514,2835,1447,1408,389,52,1825,1133,892,1169
|
-0.5386155010309926,0.9136591415130947,1.1685858128764244,-0.2938997945656019,2.528280837326959,-1.0531559749508097,-0.8560317012161593,0.13560845959237622,-0.43569894708233464,0.5430054701796704,-0.2938997945656019,0.9136591415130947,3.296890926305054,2.947996335155421,-0.19418721956236745,0.2674983597767239,-0.5801746865595289,-0.5386155010309926,-0.7062381065178011,-0.3746072665047304,-0.07619722251063903,0.6149138846414414,2.599591402744298,1.3997279417347968,-0.43569894708233464,-0.27385423081555665,-0.663982825714329,-0.07619722251063903,-0.663982825714329,-0.03726011192253851,-0.017863872838918923,0.999504346348033,3.137486998744578,-0.21402733728023318,0.13560845959237622,0.304783521666528,0.11658683691935393
| 3,425
|
metalloprotease
| 9
| 26
| 2.368839
| 0.017844
|
Q99797,Q9BYT8,P52888,P42892,Q7Z2K6,Q9NZ08,P55786,O75844,Q9UIQ6
|
Functions
|
Panther Protein class
|
panther_protein_class
|
223,358,167,107,398,113,182,154,95
|
568,2890,154,710,2282,2003,1063,3276,2326,107,167,182,727,460,1078,398,2080,887,1930,223,358,1332,2467,113,95,1621
|
0.6684312487998063,-0.7062381065178011,1.9056938106121482,0.4704535329188798,-0.4152809195710186,-0.2938997945656019,0.15458450029912923,-1.142484440376989,-0.43569894708233464,2.325553674617119,1.8285620188685285,1.7507404107076854,0.4522133253996353,0.8443364414586735,0.15458450029912923,0.9652727380057537,-0.31399754246940065,0.304783521666528,-0.25386051882213734,1.5129799522193979,1.0675480922862204,0.020785433429236007,-0.4766991906424338,2.281508618182512,2.441957508201226,-0.11532915716857117
| 3,425
|
Vacuole organization
| 12
| 59
| 2.368148
| 0.017877
|
Q9NQ11,P56962,P11117,P54802,Q14108,Q96ED9,P50897,P04062,Q96AX1,Q8N511,O14773,O75503
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
101,249,165,202,13,274,16,80,209,53,89,62
|
2886,89,1456,2417,62,590,913,2686,556,2376,80,1704,1750,421,165,724,1062,1181,639,16,2610,746,202,249,1011,1804,1108,498,13,1853,1016,317,961,1326,53,1866,209,274,676,1609,1263,477,1777,3225,906,907,101,1408,3384,2046,806,1783,1167,2640,1168,2413,1657,722,2883
|
-0.7062381065178011,2.5139509284160675,-0.056704463496115395,-0.4766991906424338,2.947996335155421,0.6327920744221581,0.2674983597767239,-0.6010399151957811,0.6861926522306766,-0.4561715837491249,2.62795906725318,-0.1743976571717926,-0.19418721956236745,0.9136591415130947,1.8285620188685285,0.4522133253996353,0.15458450029912923,0.09751936170847361,0.5610423537706956,4.33187072621963,-0.5593666767876478,0.4339317726253653,1.6247523908291193,1.3834254662027163,0.19240090545282404,-0.21402733728023318,0.13560845959237622,0.7919594158846363,4.530920591223999,-0.23391832955023042,0.19240090545282404,1.1518305804680873,0.23003816681518965,0.020785433429236007,3.1106528049037374,-0.23391832955023042,1.5610608196920086,1.3014399603266282,0.5249283688242936,-0.11532915716857117,0.05924575850806966,0.8269144177911181,-0.19418721956236745,-1.0531559749508097,0.2861626937330696,0.2861626937330696,2.3839446526313073,-0.017863872838918923,-1.7271928388381075,-0.2938997945656019,0.37883671691997084,-0.19418721956236745,0.11658683691935393,-0.5593666767876478,0.11658683691935393,-0.4561715837491249,-0.13496893733397167,0.4704535329188798,-0.6850808626505676
| 3,425
|
Mental deterioration
| 33
| 105
| 2.367731
| 0.017898
|
P03915,P16278,Q14108,P50897,Q13510,Q9BQE5,Q9UBB4,P21964,P10644,Q9NZJ7,P17900,P05067,O75306,P35670,O43681,O75503,Q9NQZ5,P03886,P54802,Q06787,P07602,Q9NPL8,P04062,Q03164,Q96F07,O15118,Q9NQ11,O60313,O95470,P35637,P00846,P06865,P27544
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
507,10,13,16,17,20,543,414,163,552,166,297,173,307,311,62,320,69,202,324,77,465,80,211,474,97,101,482,118,495,121,384,125
|
1306,97,777,311,709,482,1493,1946,173,62,691,913,1382,2375,118,1457,914,121,69,507,80,1582,915,297,384,77,1750,2152,3405,1583,3052,163,1101,3377,10,3200,166,951,1797,952,414,816,2894,125,2518,2060,495,307,1008,1841,2108,1542,1713,16,2566,2736,202,1545,3059,2067,1218,1547,2699,211,2527,2738,3119,324,1806,727,695,2820,17,13,1111,1767,1472,561,3341,2078,3223,1475,1648,2300,2787,474,1263,1000,943,2834,2875,2632,20,465,101,320,3384,2638,806,552,543,1450,2724,1168,634
|
0.020785433429236007,2.3984830795821077,0.3972437030547652,1.1685858128764244,0.4704535329188798,0.8094554736885617,-0.07619722251063903,-0.27385423081555665,1.7975170034836079,2.947996335155421,0.4886526246803302,0.2674983597767239,-0.017863872838918923,-0.4561715837491249,2.2224410858737813,-0.056704463496115395,0.2674983597767239,2.162978192726338,2.8655806296701516,0.7744260494954054,2.62795906725318,-0.11532915716857117,0.2674983597767239,1.2186519515565648,0.999504346348033,2.7125341584739417,-0.19418721956236745,-0.3543509374216771,-2.285109634377232,-0.11532915716857117,-0.8344482451084184,1.844043079409893,0.13560845959237622,-1.6303721469296955,4.600231735570217,-1.0309922696079223,1.8285620188685285,0.23003816681518965,-0.21402733728023318,0.23003816681518965,0.9308994066578831,0.36038744680166185,-0.7062381065178011,2.133096436106864,-0.5179207785497725,-0.31399754246940065,0.7919594158846363,1.1853076769616102,0.19240090545282404,-0.23391832955023042,-0.3341478103334249,-0.09573868680970035,-0.1743976571717926,4.33187072621963,-0.5386155010309926,-0.6219627517160322,1.6247523908291193,-0.09573868680970035,-0.8344482451084184,-0.31399754246940065,0.0784057608191252,-0.09573868680970035,-0.6010399151957811,1.5450638238651857,-0.5179207785497725,-0.6219627517160322,-0.8993869388026995,1.1350418152893942,-0.21402733728023318,0.4522133253996353,0.4886526246803302,-0.663982825714329,4.3200361894985715,4.530920591223999,0.13560845959237622,-0.19418721956236745,-0.056704463496115395,0.6861926522306766,-1.3475564028664557,-0.31399754246940065,-1.0531559749508097,-0.056704463496115395,-0.13496893733397167,-0.4152809195710186,-0.6429435893726733,0.8269144177911181,0.05924575850806966,0.2112417984925894,0.24879026863223094,-0.663982825714329,-0.6850808626505676,-0.5593666767876478,4.007216364080601,0.8443364414586735,2.3839446526313073,1.1518305804680873,-1.7271928388381075,-0.5593666767876478,0.37883671691997084,0.7039155427404739,0.7216001253197305,-0.03726011192253851,-0.6010399151957811,0.11658683691935393,0.5790392392161661
| 3,425
|
Adaptive immune response
| 11
| 48
| 2.364638
| 0.018048
|
O96028,P60033,Q5RKV6,Q9NUQ9,P10321,Q03519,Q9NZ08,P00813,Q9UQ84,P30511,Q96FW1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,292,264,42,396,236,113,180,310,28,191
|
1747,1493,131,1310,180,2804,710,778,1311,1706,396,3182,28,1539,1385,857,1842,1181,1386,1673,876,292,1549,1640,236,1912,1147,2117,3101,3237,2706,264,3033,2295,1078,2128,860,1974,399,191,1081,1873,532,1741,42,113,1937,310
|
-0.19418721956236745,-0.07619722251063903,2.10311335779798,0.020785433429236007,1.7663606487132952,-0.663982825714329,0.4704535329188798,0.3972437030547652,0.020785433429236007,-0.1743976571717926,0.9652727380057537,-1.00889493373649,3.6205514552672318,-0.09573868680970035,-0.017863872838918923,0.32336109245226435,-0.23391832955023042,0.09751936170847361,-0.017863872838918923,-0.15465833406450158,0.304783521666528,1.2352746846067904,-0.09573868680970035,-0.13496893733397167,1.448448785568869,-0.25386051882213734,0.11658683691935393,-0.3341478103334249,-0.8776777826591424,-1.075386542805351,-0.6010399151957811,1.3179006469481906,-0.8129269700518783,-0.4152809195710186,0.15458450029912923,-0.3341478103334249,0.32336109245226435,-0.27385423081555665,0.9652727380057537,1.703709953072957,0.15458450029912923,-0.23391832955023042,0.7392466032253644,-0.1743976571717926,3.2705115690490496,2.281508618182512,-0.25386051882213734,1.1853076769616102
| 3,425
|
Organelle inner membrane
| 73
| 272
| 2.364116
| 0.018073
|
P03915,O60830,Q99595,O95202,Q15070,Q70HW3,Q9H1E5,Q69YU5,O94901,O95167,P50402,Q7KZN9,Q8N8Q8,Q99720,O43772,Q9Y5J9,Q86Y39,Q14739,O75844,Q9H2D1,Q9BSK2,Q9NRA0,Q6P4A7,Q8IYU8,O43676,P24539,P23786,Q5XKP0,Q9Y584,O75306,Q9UDW1,Q16134,Q13423,Q9BQT8,O95831,Q9Y2R0,O75964,Q6DKK2,Q9Y5J7,Q9UJS0,Q9NX63,Q9UDX5,Q96CU9,P03886,O95168,Q13505,Q567V2,Q9H9P8,Q8IXM6,Q9NPL8,Q9Y241,Q9Y6M9,Q6NUK1,O43674,O14925,Q9Y619,Q9BRT2,P12235,Q9BYN8,Q96D53,P20674,Q9BUR5,Q9BUB7,P14406,Q9H061,Q8N6S5,O60313,Q9UBX3,Q96AQ8,Q14728,O14949,P00846,P82933
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
507,2,1,382,520,133,262,8,263,381,517,529,272,15,143,411,409,281,154,157,288,290,538,426,39,547,170,561,44,173,48,304,560,305,557,54,56,185,188,586,195,331,68,69,445,73,75,597,203,465,338,339,604,341,340,221,476,469,357,491,353,621,620,232,105,617,482,111,240,366,116,121,509
|
3408,1622,2798,931,340,116,1417,1034,740,341,39,1748,143,709,482,2,1833,1239,2186,173,1576,1172,2890,1897,1241,2945,1140,154,1175,1496,56,3247,894,263,1244,381,445,1382,2054,382,2478,1422,557,637,1457,914,121,69,507,1037,949,1178,2557,1211,2605,1424,1753,3182,469,664,3183,762,232,1101,2422,1534,1707,2770,353,1797,952,3232,1063,2245,1537,170,547,2851,3344,2518,2326,711,1539,839,2195,3249,2332,2108,1542,1278,1544,3204,3345,2565,3334,818,517,3024,2385,2810,1674,919,1545,3277,1249,2019,1185,2067,2434,1013,2202,1805,2813,2113,2070,2436,2159,3002,509,1721,1550,1504,727,2437,3371,766,2779,560,73,366,281,520,304,2535,820,959,2662,75,1596,1769,900,2028,1156,561,8,185,604,1858,538,2353,1557,696,3066,133,529,2710,1293,409,884,203,426,3156,3139,1921,617,272,3007,2666,1605,3358,1509,1197,684,3140,1117,1298,1868,1118,240,1120,68,491,825,3321,1925,964,1686,844,845,1022,1930,1,1566,15,1403,1264,305,1121,476,288,1690,620,621,1163,3315,1978,2634,357,2877,2366,105,262,157,2755,1123,720,2756,1201,1883,3088,597,2368,1406,3259,2911,465,1003,290,2044,1781,1653,647,834,1373,1300,195,1086,2914,2309,1128,1743,111,48,331,791,1004,2178,586,1412,338,1888,1029,1058,54,2596,1377,1235,737,1940,2511,1989,2051,1621,761,44,1170,188,411,911,221,635,339
|
-2.4725910422416124,-0.13496893733397167,-0.663982825714329,0.24879026863223094,1.10136302234031,2.237244780745778,-0.03726011192253851,0.17351522707522676,0.4339317726253653,1.10136302234031,3.33632142390138,-0.19418721956236745,1.9973622966526008,0.4704535329188798,0.8094554736885617,5.203448495367863,-0.23391832955023042,0.05924575850806966,-0.3746072665047304,1.7975170034836079,-0.11532915716857117,0.09751936170847361,-0.7062381065178011,-0.25386051882213734,0.05924575850806966,-0.7487318629297377,0.11658683691935393,1.9056938106121482,0.09751936170847361,-0.07619722251063903,3.0567507737172264,-1.0976844720755563,0.2861626937330696,1.3179006469481906,0.05924575850806966,0.999504346348033,0.8617217363584101,-0.017863872838918923,-0.31399754246940065,0.999504346348033,-0.4972821326535668,-0.03726011192253851,0.6861926522306766,0.5610423537706956,-0.056704463496115395,0.2674983597767239,2.162978192726338,2.8655806296701516,0.7744260494954054,0.17351522707522676,0.23003816681518965,0.09751936170847361,-0.5386155010309926,0.0784057608191252,-0.5593666767876478,-0.03726011192253851,-0.19418721956236745,-1.00889493373649,0.8269144177911181,0.5249283688242936,-1.00889493373649,0.41560864305026346,1.4646273575456767,0.13560845959237622,-0.4766991906424338,-0.09573868680970035,-0.1743976571717926,-0.6429435893726733,1.0675480922862204,-0.21402733728023318,0.23003816681518965,-1.075386542805351,0.15458450029912923,-0.39491714390968624,-0.09573868680970035,1.813053367361717,0.7039155427404739,-0.6850808626505676,-1.3707038556261375,-0.5179207785497725,-0.43569894708233464,0.4704535329188798,-0.09573868680970035,0.34189565270391015,-0.3746072665047304,-1.0976844720755563,-0.43569894708233464,-0.3341478103334249,-0.09573868680970035,0.04003907639528579,-0.09573868680970035,-1.0309922696079223,-1.3707038556261375,-0.5386155010309926,-1.32448279287036,0.36038744680166185,0.7568551780007351,-0.8129269700518783,-0.4561715837491249,-0.663982825714329,-0.15465833406450158,0.2674983597767239,-0.09573868680970035,-1.142484440376989,0.05924575850806966,-0.2938997945656019,0.09751936170847361,-0.31399754246940065,-0.4766991906424338,0.19240090545282404,-0.3746072665047304,-0.21402733728023318,-0.663982825714329,-0.3341478103334249,-0.31399754246940065,-0.4766991906424338,-0.3543509374216771,-0.79146743676524,0.7744260494954054,-0.1743976571717926,-0.09573868680970035,-0.07619722251063903,0.4522133253996353,-0.4766991906424338,-1.5824528332698784,0.41560864305026346,-0.6429435893726733,0.6861926522306766,2.8379436574544386,1.0335956619699211,1.268422139234549,0.7568551780007351,1.2019963358891592,-0.5179207785497725,0.36038744680166185,0.23003816681518965,-0.5801746865595289,2.7963313322340135,-0.11532915716857117,-0.19418721956236745,0.2861626937330696,-0.2938997945656019,0.11658683691935393,0.6861926522306766,4.669065000725359,1.7194151890935954,0.6149138846414414,-0.23391832955023042,0.7216001253197305,-0.43569894708233464,-0.09573868680970035,0.4886526246803302,-0.8344482451084184,2.10311335779798,0.7392466032253644,-0.6010399151957811,0.04003907639528579,0.9481038780076505,0.304783521666528,1.6247523908291193,0.9136591415130947,-0.9429962985415629,-0.9211596241735596,-0.25386051882213734,0.5969963442295187,1.3014399603266282,-0.79146743676524,-0.5801746865595289,-0.11532915716857117,-1.44059515439419,-0.07619722251063903,0.09751936170847361,0.5068108281574367,-0.9211596241735596,0.13560845959237622,0.04003907639528579,-0.23391832955023042,0.13560845959237622,1.4322394553880162,0.13560845959237622,2.879367974649712,0.8094554736885617,0.36038744680166185,-1.2556992813125427,-0.25386051882213734,0.23003816681518965,-0.15465833406450158,0.34189565270391015,0.34189565270391015,0.19240090545282404,-0.25386051882213734,5.246740467606561,-0.09573868680970035,4.355497276975648,-0.017863872838918923,0.05924575850806966,1.2019963358891592,0.13560845959237622,0.8269144177911181,1.2518646944415734,-0.15465833406450158,0.5969963442295187,0.5969963442295187,0.11658683691935393,-1.2329153395499515,-0.27385423081555665,-0.5593666767876478,1.0675480922862204,-0.6850808626505676,-0.43569894708233464,2.340187200505293,1.3343293891978911,1.9056938106121482,-0.6219627517160322,0.13560845959237622,0.4704535329188798,-0.6219627517160322,0.09751936170847361,-0.23391832955023042,-0.8560317012161593,0.6327920744221581,-0.43569894708233464,-0.017863872838918923,-1.0976844720755563,-0.7062381065178011,0.8443364414586735,0.2112417984925894,1.2518646944415734,-0.2938997945656019,-0.19418721956236745,-0.13496893733397167,0.5610423537706956,0.36038744680166185,0.001484545851543285,0.04003907639528579,1.6879761304662688,0.15458450029912923,-0.7062381065178011,-0.4152809195710186,0.13560845959237622,-0.1743976571717926,2.2962144810512832,3.1642440468955613,1.1350418152893942,0.3972437030547652,0.2112417984925894,-0.3543509374216771,0.6506311257033517,-0.017863872838918923,1.1182193515975896,-0.23391832955023042,0.19240090545282404,0.17351522707522676,3.097206606706352,-0.5386155010309926,0.001484545851543285,0.0784057608191252,0.4522133253996353,-0.25386051882213734,-0.4972821326535668,-0.27385423081555665,-0.2938997945656019,-0.11532915716857117,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,0.2861626937330696,1.5290369140825837,0.5790392392161661,1.1182193515975896
| 3,425
|
Establishment of protein localization to organelle
| 42
| 188
| 2.363296
| 0.018113
|
Q99595,O60830,O00505,Q15070,Q9Y5M8,Q8N8Q8,Q14108,Q9NS69,Q9Y5J9,Q8N4H5,Q8N1F7,Q92783,Q15388,Q92973,Q13043,P30419,P46934,P40855,Q9Y584,O95831,Q9UHB9,P55786,Q7Z4Q2,P57740,O43681,Q9Y5J7,P46379,Q9Y2T2,Q15005,P49257,P52294,Q5JRX3,P20645,Q15629,O14925,Q99797,O14737,Q9HD47,P30536,Q99816,O95429,Q9UGP8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,2,377,520,135,272,13,18,411,150,279,280,416,286,550,549,423,422,44,557,52,182,313,436,311,188,63,587,579,323,205,460,457,84,340,223,234,503,242,501,245,389
|
680,1092,2886,1005,3094,377,2600,234,3171,340,611,777,740,311,1994,2,2889,1456,1035,3158,1577,2890,1242,3212,1380,3323,913,2101,2604,245,2376,557,1457,1901,2805,1097,1665,1949,3077,3182,1835,1100,950,2190,795,1951,2243,2998,2771,457,3304,549,242,2061,693,2732,1499,2011,1277,3022,857,422,63,423,2015,323,2564,1758,2249,1671,667,2431,917,2610,1247,1010,205,725,1635,1280,3217,182,920,436,2658,3001,2570,1069,2900,2434,2388,2111,2337,2112,1912,1806,727,550,1250,2820,2438,13,2206,1320,3389,579,520,416,84,1323,1507,2577,1075,959,2662,460,1555,2743,2355,1158,1260,2826,313,2665,279,150,1440,272,862,1362,673,2498,1117,280,286,825,1262,2631,1000,1514,1688,686,889,2225,1,1566,223,501,2363,1404,2935,966,2835,906,1123,1447,2368,503,2790,18,1521,1233,1128,3286,2410,1985,389,52,1825,2094,609,2234,1826,1167,1133,1523,1888,587,1657,892,761,44,1170,188,411,1660,911,135
|
0.5068108281574367,0.13560845959237622,-0.7062381065178011,0.19240090545282404,-0.8776777826591424,0.999504346348033,-0.5593666767876478,1.448448785568869,-0.9868634800659423,1.10136302234031,0.5969963442295187,0.3972437030547652,0.4339317726253653,1.1685858128764244,-0.2938997945656019,5.203448495367863,-0.7062381065178011,-0.056704463496115395,0.17351522707522676,-0.9648974270030561,-0.11532915716857117,-0.7062381065178011,0.05924575850806966,-1.0531559749508097,-0.017863872838918923,-1.2785547987944277,0.2674983597767239,-0.3341478103334249,-0.5593666767876478,1.3997279417347968,-0.4561715837491249,0.6861926522306766,-0.056704463496115395,-0.25386051882213734,-0.663982825714329,0.13560845959237622,-0.15465833406450158,-0.27385423081555665,-0.8560317012161593,-1.00889493373649,-0.23391832955023042,0.13560845959237622,0.23003816681518965,-0.3746072665047304,0.37883671691997084,-0.27385423081555665,-0.39491714390968624,-0.79146743676524,-0.6429435893726733,0.8443364414586735,-1.2102024240548812,0.7039155427404739,1.4159992226041558,-0.31399754246940065,0.4886526246803302,-0.6219627517160322,-0.07619722251063903,-0.2938997945656019,0.04003907639528579,-0.8129269700518783,0.32336109245226435,0.9136591415130947,2.947996335155421,0.9136591415130947,-0.2938997945656019,1.1350418152893942,-0.5386155010309926,-0.19418721956236745,-0.39491714390968624,-0.15465833406450158,0.5249283688242936,-0.4766991906424338,0.2674983597767239,-0.5593666767876478,0.05924575850806966,0.19240090545282404,1.6088736896093438,0.4522133253996353,-0.13496893733397167,0.04003907639528579,-1.0531559749508097,1.7507404107076854,0.2674983597767239,0.8790704925764257,-0.5801746865595289,-0.79146743676524,-0.5386155010309926,0.15458450029912923,-0.7062381065178011,-0.4766991906424338,-0.4561715837491249,-0.3341478103334249,-0.43569894708233464,-0.3341478103334249,-0.25386051882213734,-0.21402733728023318,0.4522133253996353,0.7039155427404739,0.05924575850806966,-0.663982825714329,-0.4766991906424338,4.530920591223999,-0.3746072665047304,0.020785433429236007,-1.8006896901206986,0.6506311257033517,0.7568551780007351,0.9308994066578831,2.599591402744298,0.020785433429236007,-0.07619722251063903,-0.5386155010309926,0.15458450029912923,0.23003816681518965,-0.5801746865595289,0.8443364414586735,-0.09573868680970035,-0.6219627517160322,-0.43569894708233464,0.11658683691935393,0.05924575850806966,-0.663982825714329,1.1685858128764244,-0.5801746865595289,1.2849471759441964,1.95164797870373,-0.03726011192253851,1.3014399603266282,0.32336109245226435,0.001484545851543285,0.5249283688242936,-0.4972821326535668,0.13560845959237622,1.2849471759441964,1.2518646944415734,0.36038744680166185,0.05924575850806966,-0.5593666767876478,0.2112417984925894,-0.07619722251063903,-0.15465833406450158,0.5068108281574367,0.304783521666528,-0.3746072665047304,5.246740467606561,-0.09573868680970035,1.5129799522193979,0.7919594158846363,-0.43569894708233464,-0.017863872838918923,-0.7274549681465066,0.23003816681518965,-0.663982825714329,0.2861626937330696,0.13560845959237622,-0.03726011192253851,-0.43569894708233464,0.7919594158846363,-0.6429435893726733,4.212879893636516,-0.07619722251063903,0.0784057608191252,0.13560845959237622,-1.142484440376989,-0.4561715837491249,-0.27385423081555665,0.999504346348033,3.137486998744578,-0.21402733728023318,-0.31399754246940065,0.6149138846414414,-0.3746072665047304,-0.21402733728023318,0.11658683691935393,0.13560845959237622,-0.07619722251063903,-0.23391832955023042,0.6506311257033517,-0.13496893733397167,0.304783521666528,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,0.9481038780076505,-0.13496893733397167,0.2861626937330696,2.10311335779798
| 3,425
|
Inner mitochondrial membrane protein complex
| 22
| 91
| 2.361367
| 0.018208
|
Q99595,O60830,O95167,Q86Y39,Q8IYU8,O43676,Q9Y584,O75306,Q9UDW1,O75964,Q9Y5J7,Q9NX63,Q96CU9,P03886,Q13505,Q9Y6M9,O43674,O14925,P20674,P14406,O14949,P00846
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,2,381,409,426,39,44,173,48,56,188,195,68,69,73,339,341,340,353,232,116,121
|
3408,1622,931,340,116,1417,341,39,1748,2,2186,173,1576,1172,1897,1496,56,1244,381,445,1382,2054,2478,637,914,121,69,507,1178,1211,1753,664,762,232,1101,2422,1534,2770,353,952,1063,547,2851,3344,2518,2326,1539,839,3249,1544,3204,3334,2385,1249,2019,1185,2067,73,2535,820,959,2662,1596,561,696,409,426,1509,68,825,845,1,1566,1403,621,2368,1653,834,1300,195,1128,48,2178,1888,737,1621,761,44,1170,188,339
|
-2.4725910422416124,-0.13496893733397167,0.24879026863223094,1.10136302234031,2.237244780745778,-0.03726011192253851,1.10136302234031,3.33632142390138,-0.19418721956236745,5.203448495367863,-0.3746072665047304,1.7975170034836079,-0.11532915716857117,0.09751936170847361,-0.25386051882213734,-0.07619722251063903,3.0567507737172264,0.05924575850806966,0.999504346348033,0.8617217363584101,-0.017863872838918923,-0.31399754246940065,-0.4972821326535668,0.5610423537706956,0.2674983597767239,2.162978192726338,2.8655806296701516,0.7744260494954054,0.09751936170847361,0.0784057608191252,-0.19418721956236745,0.5249283688242936,0.41560864305026346,1.4646273575456767,0.13560845959237622,-0.4766991906424338,-0.09573868680970035,-0.6429435893726733,1.0675480922862204,0.23003816681518965,0.15458450029912923,0.7039155427404739,-0.6850808626505676,-1.3707038556261375,-0.5179207785497725,-0.43569894708233464,-0.09573868680970035,0.34189565270391015,-1.0976844720755563,-0.09573868680970035,-1.0309922696079223,-1.32448279287036,-0.4561715837491249,0.05924575850806966,-0.2938997945656019,0.09751936170847361,-0.31399754246940065,2.8379436574544386,-0.5179207785497725,0.36038744680166185,0.23003816681518965,-0.5801746865595289,-0.11532915716857117,0.6861926522306766,0.4886526246803302,0.9481038780076505,0.9136591415130947,-0.07619722251063903,2.879367974649712,0.36038744680166185,0.34189565270391015,5.246740467606561,-0.09573868680970035,-0.017863872838918923,0.5969963442295187,-0.43569894708233464,-0.13496893733397167,0.36038744680166185,0.04003907639528579,1.6879761304662688,0.13560845959237622,3.1642440468955613,-0.3543509374216771,-0.23391832955023042,0.4522133253996353,-0.11532915716857117,0.4339317726253653,3.2440577254623797,0.11658683691935393,1.7194151890935954,1.1182193515975896
| 3,425
|
Threonine type peptidase activity
| 6
| 9
| 2.35532
| 0.018507
|
P28074,Q9UJ14,P28070,P20618,P49721,P28072
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
448,467,206,208,23,26
|
208,2692,206,26,448,1353,23,605,467
|
1.5610608196920086,-0.6010399151957811,1.592965616941986,3.6839797644624737,0.8617217363584101,0.001484545851543285,3.734421078054943,0.6149138846414414,0.8443364414586735
| 3,425
|
Respiratory chain
| 13
| 41
| 2.352962
| 0.018625
|
Q96CU9,O95167,O43676,P03886,O95168,O75306,Q9UDW1,Q9Y241,Q9Y6M9,O14949,Q86Y39,O43674,Q6DKK2
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
68,381,39,69,445,173,48,338,339,116,409,341,185
|
3408,1622,116,1417,341,39,1748,2186,173,1576,1897,1244,381,445,1382,2054,2478,637,914,69,507,1211,2422,2770,1063,3344,2326,1544,3334,2385,2067,2535,185,409,68,1300,1128,48,2178,338,339
|
-2.4725910422416124,-0.13496893733397167,2.237244780745778,-0.03726011192253851,1.10136302234031,3.33632142390138,-0.19418721956236745,-0.3746072665047304,1.7975170034836079,-0.11532915716857117,-0.25386051882213734,0.05924575850806966,0.999504346348033,0.8617217363584101,-0.017863872838918923,-0.31399754246940065,-0.4972821326535668,0.5610423537706956,0.2674983597767239,2.8655806296701516,0.7744260494954054,0.0784057608191252,-0.4766991906424338,-0.6429435893726733,0.15458450029912923,-1.3707038556261375,-0.43569894708233464,-0.09573868680970035,-1.32448279287036,-0.4561715837491249,-0.31399754246940065,-0.5179207785497725,1.7194151890935954,0.9481038780076505,2.879367974649712,0.04003907639528579,0.13560845959237622,3.1642440468955613,-0.3543509374216771,1.1182193515975896,1.1182193515975896
| 3,425
|
Passive transmembrane transporter activity
| 7
| 36
| 2.352184
| 0.018664
|
Q9C0H2,P21796,P51790,P45880,O75964,P00846,Q9Y277
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
70,5,204,14,56,121,220
|
2315,1496,56,1457,121,1178,1704,2946,2923,5,547,2851,430,839,1841,14,3204,204,1249,1185,2900,2203,799,3256,1509,1975,964,803,223,2965,70,3406,834,1056,220,3333
|
-0.43569894708233464,-0.07619722251063903,3.0567507737172264,-0.056704463496115395,2.162978192726338,0.09751936170847361,-0.1743976571717926,-0.7487318629297377,-0.7274549681465066,4.917492659435559,0.7039155427404739,-0.6850808626505676,0.8963828986355812,0.34189565270391015,-0.23391832955023042,4.496083243944842,-1.0309922696079223,1.6088736896093438,0.05924575850806966,0.09751936170847361,-0.7062381065178011,-0.3746072665047304,0.37883671691997084,-1.0976844720755563,-0.07619722251063903,-0.27385423081555665,0.23003816681518965,0.37883671691997084,1.5129799522193979,-0.7487318629297377,2.8655806296701516,-2.285109634377232,0.36038744680166185,0.17351522707522676,1.5290369140825837,-1.3014824482535676
| 3,425
|
Endosome organization
| 9
| 31
| 2.351177
| 0.018714
|
O43752,Q8IYI6,P51790,Q14108,Q96ED9,Q2M389,Q99816,Q12768,Q92783
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
379,326,204,13,274,397,501,498,280
|
1420,379,1575,1946,2733,2610,204,1106,1430,498,13,2534,397,961,326,1562,1198,280,274,501,1404,847,1479,1447,573,2270,1783,2941,1167,1168,722
|
-0.03726011192253851,0.999504346348033,-0.11532915716857117,-0.27385423081555665,-0.6219627517160322,-0.5593666767876478,1.6088736896093438,0.13560845959237622,-0.03726011192253851,0.7919594158846363,4.530920591223999,-0.5179207785497725,0.9652727380057537,0.23003816681518965,1.1350418152893942,-0.09573868680970035,0.09751936170847361,1.2849471759441964,1.3014399603266282,0.7919594158846363,-0.017863872838918923,0.34189565270391015,-0.056704463496115395,-0.03726011192253851,0.6684312487998063,-0.39491714390968624,-0.19418721956236745,-0.7274549681465066,0.11658683691935393,0.11658683691935393,0.4704535329188798
| 3,425
|
EF-hand domain pair [IPR011992]
| 18
| 50
| 2.347057
| 0.018922
|
O43852,Q9UJS0,Q9NWM8,O95202,P07384,P80303,Q14257,Q8IYU8,Q9BRK5,Q99584,O75071,Q9Y680,Q02818,P41208,O95302,Q6NUK1,Q96AY3,Q9UPN3
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
380,586,194,382,352,6,168,426,370,595,144,50,51,277,85,604,243,455
|
1237,380,144,2477,1140,382,85,352,1383,3288,2892,3275,2849,873,1754,277,1278,1464,858,6,51,1677,1149,2120,168,2928,2162,1599,604,3167,1862,2218,426,3125,700,243,2135,1328,595,1403,370,633,849,721,194,2840,1337,586,455,50
|
0.05924575850806966,0.999504346348033,1.9973622966526008,-0.4972821326535668,0.11658683691935393,0.999504346348033,2.5568725955541236,1.0675480922862204,-0.017863872838918923,-1.1649875074107834,-0.7062381065178011,-1.142484440376989,-0.6850808626505676,0.304783521666528,-0.19418721956236745,1.2849471759441964,0.04003907639528579,-0.056704463496115395,0.32336109245226435,4.895159421570552,3.137486998744578,-0.15465833406450158,0.11658683691935393,-0.3341478103334249,1.8285620188685285,-0.7274549681465066,-0.3543509374216771,-0.11532915716857117,0.6149138846414414,-0.9648974270030561,-0.23391832955023042,-0.3746072665047304,0.9136591415130947,-0.8993869388026995,0.4886526246803302,1.4159992226041558,-0.3341478103334249,0.020785433429236007,0.6327920744221581,-0.017863872838918923,1.0335956619699211,0.5790392392161661,0.34189565270391015,0.4704535329188798,1.6879761304662688,-0.663982825714329,0.020785433429236007,0.6506311257033517,0.8617217363584101,3.1508751318963872
| 3,425
|
Subsets and Splits
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