term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Subcutaneous nodule
9
17
2.345618
0.018996
P31749,P06280,P11802,Q9NZ08,Q13510,P49327,P35637,P52732,Q9NSE4
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
693,139,429,113,17,526,495,155,512
1379,2804,139,429,952,693,1755,495,875,526,155,3166,17,717,512,113,1235
-0.017863872838918923,-0.663982825714329,2.057946899190213,0.8963828986355812,0.23003816681518965,0.4886526246803302,-0.19418721956236745,0.7919594158846363,0.304783521666528,0.7392466032253644,1.9056938106121482,-0.9648974270030561,4.3200361894985715,0.4704535329188798,0.7744260494954054,2.281508618182512,0.0784057608...
3,425
Retinopathy
12
28
2.345262
0.019014
O96028,O95202,Q8NBM4,P51648,O75306,P11802,Q9NZ08,O43819,P49327,P00846,P52732,Q15555
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
131,382,717,141,173,429,113,709,526,121,155,602
2969,709,1061,173,1382,382,131,121,2804,1272,429,951,1275,857,2332,1669,526,141,155,2696,2958,602,1438,717,1688,1654,113,737
-0.7700692108929594,0.4704535329188798,0.15458450029912923,1.7975170034836079,-0.017863872838918923,0.999504346348033,2.10311335779798,2.162978192726338,-0.663982825714329,0.04003907639528579,0.8963828986355812,0.23003816681518965,0.04003907639528579,0.32336109245226435,-0.43569894708233464,-0.15465833406450158,0.73924...
3,425
Limb ataxia
10
26
2.332411
0.019679
O14773,P07196,P07384,Q14108,Q8IV08,P04062,P41440,Q12768,O75298,Q9NR77
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
89,447,352,13,79,80,458,498,403,29
3245,2761,89,2970,403,80,1582,447,352,2848,1101,1347,2518,2924,458,727,498,13,79,2497,2875,2137,29,543,2724,1621
-1.0976844720755563,-0.6429435893726733,2.5139509284160675,-0.7700692108929594,0.9481038780076505,2.62795906725318,-0.11532915716857117,0.8617217363584101,1.0675480922862204,-0.6850808626505676,0.13560845959237622,0.001484545851543285,-0.5179207785497725,-0.7274549681465066,0.8443364414586735,0.4522133253996353,0.79195...
3,425
Protein localization to lysosome
7
17
2.32315
0.020171
P60033,Q9NQ11,P46934,Q14108,P20645,Q9NQC3,Q9NUN5
Processes and pathways
GO Biological process
msigdb_gobp
292,101,423,13,457,210,145
2886,2600,1137,1835,795,457,423,2610,292,13,1260,686,101,210,145,1167,587
-0.7062381065178011,-0.5593666767876478,0.11658683691935393,-0.23391832955023042,0.37883671691997084,0.8443364414586735,0.9136591415130947,-0.5593666767876478,1.2352746846067904,4.530920591223999,0.05924575850806966,0.5068108281574367,2.3839446526313073,1.5610608196920086,1.9973622966526008,0.11658683691935393,0.650631...
3,425
Metalloendopeptidase activity
7
14
2.317268
0.020489
Q99797,Q9BYT8,Q92905,P52888,P42892,Q5JRX3,O75844
Functions
GO Molecular function
msigdb_gomf
223,358,260,167,107,460,154
568,2890,154,2003,1063,107,167,727,460,260,1930,223,358,1621
0.6684312487998063,-0.7062381065178011,1.9056938106121482,-0.2938997945656019,0.15458450029912923,2.325553674617119,1.8285620188685285,0.4522133253996353,0.8443364414586735,1.3343293891978911,-0.25386051882213734,1.5129799522193979,1.0675480922862204,-0.11532915716857117
3,425
Delusions
9
20
2.304354
0.021203
P21964,Q9UI10,Q9NZJ7,P07602,P04062,Q96DF8,Q9BQE5,P49770,O43681
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
414,493,552,77,80,273,20,346,311
2761,311,80,77,2152,3377,414,1709,2195,346,818,2489,2207,273,1000,20,1126,552,493,586
-0.6429435893726733,1.1685858128764244,2.62795906725318,2.7125341584739417,-0.3543509374216771,-1.6303721469296955,0.9308994066578831,-0.1743976571717926,-0.3746072665047304,1.0844726591413512,0.36038744680166185,-0.4972821326535668,-0.3746072665047304,1.3014399603266282,0.2112417984925894,4.007216364080601,0.135608459...
3,425
Proton transmembrane transport
13
47
2.30265
0.021299
P03915,P20674,Q96ES6,P24539,Q7KZN9,P51790,Q9UDW1,Q13423,O00400,O75964,P00846,Q9NRA0,P12235
Processes and pathways
GO Biological process
msigdb_gobp
507,353,231,547,529,204,48,560,86,56,121,290,469
86,1622,931,1528,1237,2186,1496,56,914,121,507,916,949,1178,1211,1753,469,762,1101,353,982,2104,547,2851,3132,2326,839,1008,1841,1544,3204,204,1249,1185,600,1721,560,529,231,2834,1566,1201,290,48,1825,1339,1412
2.5425880302168293,-0.13496893733397167,0.24879026863223094,-0.09573868680970035,0.05924575850806966,-0.3746072665047304,-0.07619722251063903,3.0567507737172264,0.2674983597767239,2.162978192726338,0.7744260494954054,0.2674983597767239,0.23003816681518965,0.09751936170847361,0.0784057608191252,-0.19418721956236745,0.82...
3,425
Cataract
7
28
2.293954
0.021793
Q8N2K0,O00116,P08670,Q15800,O00400,Q15125,Q9H6K4
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
489,199,359,43,86,151,57
199,86,1745,2238,691,1662,359,1274,951,2107,1587,1500,2566,2116,151,43,2708,2662,1555,489,1605,1973,2300,1054,906,57,512,791
1.6564222106812256,2.5425880302168293,-0.19418721956236745,-0.39491714390968624,0.4886526246803302,-0.15465833406450158,1.0505891507074792,0.04003907639528579,0.23003816681518965,-0.3341478103334249,-0.11532915716857117,-0.07619722251063903,-0.5386155010309926,-0.3341478103334249,1.9210387080998343,3.2440577254623797,-...
3,425
Abnormality of pulmonary circulation
14
32
2.289926
0.022026
O95235,P03915,P31749,P20674,O96000,Q8IZA0,P03886,Q14108,P04062,Q96AX1,Q9NZ08,P49327,Q6NUK1,O75844
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
383,507,693,353,637,259,69,13,80,209,113,526,604,154
1240,154,383,637,914,2804,1901,69,507,80,2647,1101,353,3304,2851,693,1957,526,1845,2385,13,2702,2352,2214,604,994,259,717,209,2268,113,2414
0.05924575850806966,1.9056938106121482,0.999504346348033,0.5610423537706956,0.2674983597767239,-0.663982825714329,-0.25386051882213734,2.8655806296701516,0.7744260494954054,2.62795906725318,-0.5801746865595289,0.13560845959237622,1.0675480922862204,-1.2102024240548812,-0.6850808626505676,0.4886526246803302,-0.273854230...
3,425
Cation transport
41
167
2.289598
0.022045
P03915,O95202,P21796,Q70HW3,Q7KZN9,O43772,O75844,Q9NRA0,Q96PU5,Q8IYU8,P24539,P46934,P05067,Q9UDW1,Q13423,P35670,O75964,Q8NEW0,Q8N4V1,Q8N1S5,Q06787,P51790,Q15043,O00400,Q9Y619,Q6NXT4,Q6PML9,P12235,P20674,Q9NQ11,O15173,Q96ES6,P07384,P20020,Q96AQ8,Q9HD47,P30536,Q9HD20,P11413,P00846,Q9Y6M7
Processes and pathways
GO Biological process
msigdb_gobp
507,382,5,133,529,143,154,290,417,426,547,423,297,48,560,307,56,314,186,327,324,204,335,86,221,348,349,469,353,101,229,231,352,235,240,503,242,244,494,121,390
3157,86,1306,1622,931,1528,775,229,1237,143,813,814,2239,1833,2186,2890,154,1496,56,691,382,2686,2993,914,121,710,507,916,1533,297,949,2320,1178,1704,352,2946,2151,1211,1753,2947,494,469,762,1836,1101,724,1313,3020,2849,235,353,982,2104,3304,5,547,2193,2851,1103,2950,3132,242,873,571,693,2326,2652,1384,1755,307,839,100...
-0.9648974270030561,2.5425880302168293,0.020785433429236007,-0.13496893733397167,0.24879026863223094,-0.09573868680970035,0.3972437030547652,1.4807753146449134,0.05924575850806966,1.9973622966526008,0.36038744680166185,0.36038744680166185,-0.39491714390968624,-0.23391832955023042,-0.3746072665047304,-0.7062381065178011...
3,425
Organic acid transport
19
48
2.286032
0.022252
O43772,P31751,O60831,Q9H2D1,Q6P4A7,P33527,P23786,Q96H78,Q9BQT8,P30825,Q9UJS0,P50416,P08183,P14174,P53985,P41440,Q9Y619,Q15041,Q9UBX3
Processes and pathways
GO Biological process
msigdb_gobp
143,653,402,157,538,666,170,47,305,571,586,449,322,333,591,458,221,601,111
1528,1746,2514,143,813,402,1140,2150,2057,2765,778,2320,3129,322,2151,1274,333,170,871,1799,571,693,653,2327,666,458,449,1674,591,1067,1550,1250,601,1015,1814,538,3256,47,1022,1735,305,157,1201,1883,111,586,892,221
-0.09573868680970035,-0.19418721956236745,-0.5179207785497725,1.9973622966526008,0.36038744680166185,0.9481038780076505,0.11658683691935393,-0.3543509374216771,-0.31399754246940065,-0.6429435893726733,0.3972437030547652,-0.43569894708233464,-0.9211596241735596,1.1350418152893942,-0.3543509374216771,0.04003907639528579,...
3,425
Cell recognition
10
26
2.283741
0.022387
Q8WTV0,P35613,P60033,Q5KU26,Q14157,P05067,Q9Y639,Q9BY67,P45880,Q9NQC3
Processes and pathways
GO Biological process
msigdb_gobp
64,254,292,486,391,297,364,532,14,210
811,3261,3147,297,2243,2006,254,1756,14,2015,2564,2431,917,292,1357,2112,391,486,537,64,1442,2358,2363,532,210,364
0.36038744680166185,-1.1200502676254012,-0.9429962985415629,1.2186519515565648,-0.39491714390968624,-0.2938997945656019,1.3507263392996962,-0.19418721956236745,4.496083243944842,-0.2938997945656019,-0.5386155010309926,-0.4766991906424338,0.2674983597767239,1.2352746846067904,0.001484545851543285,-0.3341478103334249,0.9...
3,425
Abnormal circulating lipid concentration
30
79
2.282245
0.022475
P50402,P06280,Q92734,O43772,P31751,Q9NUN5,Q15125,O75844,Q14739,O75845,Q15392,Q9NZJ7,P23786,Q15800,P40855,Q15904,Q8N511,Q4G0N4,Q13045,P57740,Q9UJS0,P50416,P49257,P07602,P28070,Q16836,P34913,Q13426,O95470,Q9NVI7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
517,139,656,143,653,145,151,154,281,162,36,552,170,43,422,177,53,437,312,436,586,449,323,77,206,603,470,614,118,647
1891,1237,1830,143,1577,1172,154,162,1175,118,1900,1901,139,1628,77,2001,3380,2245,170,206,1065,653,470,2286,1668,3201,1009,3289,422,2332,2015,323,2565,517,449,2566,2198,2980,3277,920,436,1218,2858,1638,1504,989,312,614,1551,281,1190,151,36,1915,43,177,603,437,2216,2496,53,2497,1441,824,656,1924,1690,2756,1371,145,647,...
-0.25386051882213734,0.05924575850806966,-0.23391832955023042,1.9973622966526008,-0.11532915716857117,0.09751936170847361,1.9056938106121482,1.844043079409893,0.09751936170847361,2.2224410858737813,-0.25386051882213734,-0.25386051882213734,2.057946899190213,-0.13496893733397167,2.7125341584739417,-0.2938997945656019,-1...
3,425
Mitochondrial complex iv assembly
7
14
2.268447
0.023302
P20674,P14406,Q8N8Q8,Q7KZN9,Q9Y241,O43819,Q9Y2R0
Processes and pathways
WikiPathways
msigdb_wp
353,232,272,529,338,709,54
1622,709,914,1753,762,232,1101,1534,353,529,272,999,338,54
-0.13496893733397167,0.4704535329188798,0.2674983597767239,-0.19418721956236745,0.41560864305026346,1.4646273575456767,0.13560845959237622,-0.09573868680970035,1.0675480922862204,0.7392466032253644,1.3014399603266282,0.2112417984925894,1.1182193515975896,3.097206606706352
3,425
Regulation of macroautophagy
16
55
2.268429
0.023303
P61421,O15118,P21796,P07384,Q8IYI6,P09601,P46934,Q9NQ11,O15269,P04062,Q9Y487,Q9Y2S7,Q93050,Q5VWJ9,P27544,P12235
Processes and pathways
GO Biological process
msigdb_gobp
600,97,5,352,326,102,423,101,172,80,634,513,473,317,125,469
1992,97,172,1095,2417,741,2686,2376,80,3049,2805,949,352,1212,102,469,1313,3020,982,2104,5,855,125,693,1008,1841,1181,1756,423,1039,600,2203,317,2296,326,1866,473,1119,1609,1263,2225,906,101,970,1166,657,1339,1376,1451,513,1657,634,1031,1135,2414
-0.2938997945656019,2.3984830795821077,1.7975170034836079,0.13560845959237622,-0.4766991906424338,0.4339317726253653,-0.6010399151957811,-0.4561715837491249,2.62795906725318,-0.8344482451084184,-0.663982825714329,0.23003816681518965,1.0675480922862204,0.0784057608191252,2.3693825937809168,0.8269144177911181,0.020785433...
3,425
Protein localization to endoplasmic reticulum
7
35
2.26842
0.023304
Q9Y5M8,P24390,Q9NQC3,Q9UHB9,Q15629,O43681,P46379
Processes and pathways
GO Biological process
msigdb_gobp
135,12,210,52,84,311,63
739,1346,480,311,1994,3212,3077,2244,12,2011,63,1758,1247,2658,1011,3001,2570,1069,2900,579,84,1438,2355,717,1867,1977,1514,906,210,2369,389,52,944,1133,135
0.4339317726253653,0.001484545851543285,0.8094554736885617,1.1685858128764244,-0.2938997945656019,-1.0531559749508097,-0.8560317012161593,-0.39491714390968624,4.5656364088713355,-0.2938997945656019,2.947996335155421,-0.19418721956236745,0.05924575850806966,-0.5801746865595289,0.19240090545282404,-0.79146743676524,-0.53...
3,425
Central scotoma
6
10
2.261745
0.023713
P03886,Q9H061,O60313,O75306,P00846,Q9H6K4
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
69,105,482,173,121,57
1306,482,173,913,121,69,507,3232,105,57
0.020785433429236007,0.8094554736885617,1.7975170034836079,0.2674983597767239,2.162978192726338,2.8655806296701516,0.7744260494954054,-1.075386542805351,2.340187200505293,3.0432261828019507
3,425
Insertion of tail anchored proteins into the endoplasmic reticulum membrane
6
12
2.259151
0.023874
P09601,P05067,P51648,P49069,O43681,P46379
Processes and pathways
Reactome Pathways
msigdb_reactome
102,297,141,431,311,63
311,1994,297,102,63,431,517,141,2658,1284,2355,2369
1.1685858128764244,-0.2938997945656019,1.2186519515565648,2.3693825937809168,2.947996335155421,0.8963828986355812,0.7568551780007351,2.027706771884764,-0.5801746865595289,0.04003907639528579,-0.43569894708233464,-0.43569894708233464
3,425
Peptidase activity
52
122
2.257146
0.023999
Q92905,O75976,Q9BXS4,Q7Z2K6,P67812,P49721,P28072,O75844,Q9HB40,Q13107,Q96RU2,P42785,Q13043,P52888,Q2T9J0,Q96K76,P55786,Q9HD42,O43847,P60900,Q96FW1,P28074,Q4J6C6,Q15005,Q9H8M7,Q16740,Q99538,Q9UJ14,P55210,P28070,P20618,P02786,Q5JRX3,O14773,Q9BT78,Q92542,Q99436,Q10713,Q9UIQ6,Q99797,Q9BYT8,P07384,O43292,Q9H3G5,P42892,Q9282...
Functions
GO Molecular function
msigdb_gomf
260,516,138,398,269,23,26,154,30,669,287,37,550,167,308,309,182,573,568,190,191,448,580,579,721,74,718,467,713,206,208,710,460,89,607,733,605,727,95,223,358,352,480,106,107,238,113,241,114,376,626,649
1454,1490,89,868,480,777,568,2890,154,516,3247,2418,710,352,626,114,2282,2153,2003,3275,208,1063,2692,206,26,448,3276,3131,2951,2195,1587,2733,1756,37,107,2897,817,1353,23,2695,1716,167,1635,876,2484,713,182,190,3001,269,3118,3061,2984,727,2902,550,669,1723,2903,579,74,308,580,2494,460,1290,2295,882,1078,2905,2447,398,...
-0.056704463496115395,-0.07619722251063903,2.5139509284160675,0.304783521666528,0.8094554736885617,0.3972437030547652,0.6684312487998063,-0.7062381065178011,1.9056938106121482,0.7568551780007351,-1.0976844720755563,-0.4766991906424338,0.4704535329188798,1.0675480922862204,0.5790392392161661,2.2667784467407786,-0.415280...
3,425
Transporters
144
417
2.254462
0.024167
Q15070,P24390,Q14108,P45880,Q99720,Q9NPI6,Q969E2,Q9NR77,Q6P4A7,Q9NZJ7,Q5VW38,Q96H78,Q9UHB9,Q8N511,O95295,P30825,O60443,Q8NE01,Q8WTV0,Q5BJF2,Q9UJS0,Q9C0H2,O60637,P07602,P53985,Q15629,O75787,O00400,Q6NUK1,Q99805,Q15363,P61421,O15118,O15260,Q9NQ11,Q9BUR5,Q9BUB7,Q9H061,Q8TB61,Q9UBX3,O15397,Q9Y6C9,Q8NHH9,O14972,Q16611,Q0872...
Functions
Protein Atlas Protein class
protein_atlas_protein_class
520,12,13,14,15,533,539,29,538,552,38,47,52,53,556,571,60,582,64,65,586,70,71,77,591,84,590,86,604,606,93,600,97,99,101,621,620,105,109,111,611,635,632,117,629,628,646,133,138,657,142,143,145,147,149,152,676,154,157,673,666,664,686,684,682,177,178,707,706,183,701,186,689,691,205,219,221,226,227,233,236,235,239,244,249,...
1489,2555,3157,2315,86,1005,2182,1306,689,377,419,1455,332,1528,811,3171,1093,117,1746,1033,97,2918,142,1346,99,378,611,2514,812,1943,311,2645,379,143,813,814,482,2729,794,60,1575,71,1136,2148,2992,852,402,1833,1456,947,2477,3145,1577,741,980,1242,1140,590,154,2150,853,691,3212,263,1898,1579,2278,895,913,382,2845,556,2...
-0.07619722251063903,-0.5386155010309926,-0.9648974270030561,-0.43569894708233464,2.5425880302168293,0.19240090545282404,-0.3746072665047304,0.020785433429236007,0.4886526246803302,0.999504346348033,0.9136591415130947,-0.056704463496115395,1.1182193515975896,-0.09573868680970035,0.36038744680166185,-0.9868634800659423,...
3,425
Autophagy of mitochondrion
13
33
2.251154
0.024376
P49840,P21796,Q9NQ11,P50851,P04062,O00165,P30536,P53365,Q16543,Q9BWH2,P52789,P27544,P12235
Processes and pathways
GO Biological process
msigdb_gobp
667,5,101,639,80,680,242,746,347,388,725,125,469
680,1306,777,1456,913,80,2805,949,469,2771,5,125,242,667,639,725,746,1011,1913,347,1919,2665,1648,2834,1566,388,1123,101,970,1408,2094,892,2883
0.5068108281574367,0.020785433429236007,0.3972437030547652,-0.056704463496115395,0.2674983597767239,2.62795906725318,-0.663982825714329,0.23003816681518965,0.8269144177911181,-0.6429435893726733,4.917492659435559,2.133096436106864,1.4159992226041558,0.5249283688242936,0.5610423537706956,0.4522133253996353,0.43393177262...
3,425
Abnormal protein glycosylation
6
20
2.250434
0.024421
Q9BT22,Q15904,O75787,Q8N511,Q96AA3,Q9NP73
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
361,177,590,53,152,376
1061,2477,590,1429,1008,2608,1841,2331,918,989,177,1076,53,152,361,1299,1371,376,634,1205
0.15458450029912923,-0.4972821326535668,0.6327920744221581,-0.03726011192253851,0.19240090545282404,-0.5593666767876478,-0.23391832955023042,-0.43569894708233464,0.2674983597767239,0.2112417984925894,1.7819528049746483,0.15458450029912923,3.1106528049037374,1.9210387080998343,1.0505891507074792,0.04003907639528579,0.00...
3,425
transmembrane signal receptor
6
8
2.249731
0.024466
O15173,O00264,Q9UMX5,Q8WUJ1,Q99720,O75787
Functions
Panther Protein class
panther_protein_class
229,514,76,110,15,590
514,229,590,110,676,15,2092,76
0.7568551780007351,1.4807753146449134,0.6327920744221581,2.3108961338926965,0.5249283688242936,4.355497276975648,-0.31399754246940065,2.7963313322340135
3,425
Neuromuscular process
7
26
2.245744
0.02472
P07196,P17900,P10253,P05067,P04062,O14773,O75844
Processes and pathways
GO Biological process
msigdb_gobp
447,166,421,297,80,89,154
89,1493,154,80,297,447,1750,421,166,1347,1181,2734,1713,2736,1068,937,2524,1111,2395,3223,1602,1971,461,1263,1366,2230
2.5139509284160675,-0.07619722251063903,1.9056938106121482,2.62795906725318,1.2186519515565648,0.8617217363584101,-0.19418721956236745,0.9136591415130947,1.8285620188685285,0.001484545851543285,0.09751936170847361,-0.6219627517160322,-0.1743976571717926,-0.6219627517160322,0.15458450029912923,0.24879026863223094,-0.517...
3,425
Intra golgi traffic
6
15
2.245578
0.024731
O15498,O00461,O95721,O43752,O60476,O95249
Processes and pathways
Reactome Pathways
msigdb_reactome
506,66,663,379,302,303
66,506,379,302,303,663,1588,1546,2737,1284,1016,701,1737,1371,1333
2.879367974649712,0.7744260494954054,0.999504346348033,1.2019963358891592,1.2019963358891592,0.5249283688242936,-0.11532915716857117,-0.09573868680970035,-0.6219627517160322,0.04003907639528579,0.19240090545282404,0.4886526246803302,-0.1743976571717926,0.001484545851543285,0.020785433429236007
3,425
Ferroptosis
6
24
2.243871
0.024841
P09601,P45880,Q15043,Q9Y277,Q9NZ45,Q9UKU0
Processes and pathways
WikiPathways
msigdb_wp
102,14,335,220,124,158
1995,2057,710,2805,3213,2151,102,435,1349,2327,1009,14,1104,1906,335,1321,1724,1015,2930,1735,124,2270,158,220
-0.2938997945656019,-0.31399754246940065,0.4704535329188798,-0.663982825714329,-1.0531559749508097,-0.3543509374216771,2.3693825937809168,0.8790704925764257,0.001484545851543285,-0.43569894708233464,0.19240090545282404,4.496083243944842,0.13560845959237622,-0.25386051882213734,1.1182193515975896,0.020785433429236007,-0...
3,425
Ion transport
23
61
2.238792
0.025169
O95202,P21796,P45880,P24539,Q15904,P35670,Q8NEW0,O75964,Q8NE01,Q9C0H2,Q8N1S5,P51790,Q9H0H5,Q15043,Q9Y277,Q93050,Q6NXT4,Q6PML9,P61421,P20020,Q96AQ8,P00846,Q9Y6M7
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
382,5,14,547,177,307,314,56,582,70,327,204,464,335,220,473,348,349,600,235,240,121,390
2315,1496,56,382,1457,121,916,1533,1178,2923,724,235,982,2104,5,547,2851,307,839,1008,1841,14,3204,204,2657,1067,1249,1185,600,780,1393,335,177,799,3394,348,1291,349,3256,327,582,1509,314,473,240,964,1735,803,1403,2965,70,464,3406,834,1339,1056,220,634,1031,3333,390
-0.43569894708233464,-0.07619722251063903,3.0567507737172264,0.999504346348033,-0.056704463496115395,2.162978192726338,0.2674983597767239,-0.09573868680970035,0.09751936170847361,-0.7274549681465066,0.4522133253996353,1.448448785568869,0.2112417984925894,-0.3341478103334249,4.917492659435559,0.7039155427404739,-0.68508...
3,425
Golgi apparatus
99
339
4.351464
0.000014
Q15691,P80303,P24390,Q99523,Q10472,Q8IV08,O14773,Q9BZG1,O15027,P50897,Q5VW38,Q15392,Q9UPN3,Q9Y282,Q02818,Q14108,Q7Z5K2,O00429,Q9UQB8,O95721,P51809,Q15436,P35606,P20645,P11717,O95070,P30511,P06280,O15260,Q9Y3B3,O00461,Q9Y2C2,Q9P260,O14579,O15498,O95249,O43505,Q8IZA0,Q96ED9,O15118,Q8NCM8,P46934,Q8TB61,P50851,Q6VY07,O7550...
Localization
GO Cellular component
msigdb_gocc
510,4,8,528,522,20,23,540,531,29,34,35,558,40,42,43,551,50,51,562,580,583,579,574,573,572,79,83,88,90,104,628,108,603,604,606,110,114,115,119,121,127,165,161,175,178,186,189,188,195,211,209,216,218,236,237,238,247,265,290,292,305,297,314,312,319,330,325,333,342,337,353,354,370,369,365,358,378,375,387,390,381,398,397,39...
1612,2062,2277,216,50,1975,104,603,1376,825,3084,826,23,2151,480,531,119,2740,188,1247,1881,88,604,2470,2504,110,1615,358,1616,1250,381,265,195,2952,867,1424,770,3305,178,1133,2588,572,325,482,606,3031,237,1694,2775,562,2474,1213,2070,2544,218,1936,2589,392,83,1981,3357,1740,2159,609,773,2249,337,1303,573,297,1893,1512...
-0.038584078694405555,-0.2635077801131671,-0.37784236620718575,1.3607996071828967,3.0414693740755707,-0.21813043469859994,2.0508529552783132,0.567173303638535,0.07209397481136083,0.3760787952122493,-0.9458869350673296,0.3760787952122493,4.034961034471749,-0.3090872955507271,0.7551076998175745,0.6719602277437084,1.91950...
3,424
Organonitrogen compound catabolic process
107
384
3.904232
0.000095
Q13126,O14965,P00813,Q9NUJ1,Q9UHG3,Q92990,P49721,P10619,P46379,O75150,Q13042,P20618,O14773,Q9GZP9,P28072,P09601,P50897,O43598,Q96KB5,Q8N511,Q9H9H4,Q13510,Q9BRG1,Q5T4S7,P28070,P49720,P60033,Q96H78,P30519,O60502,Q4ZIN3,Q8NBM8,P31749,Q8WTV0,Q9UJX4,Q9UBS8,Q9NWU2,P06280,O43633,P42892,Q8NCC3,P36639,P54727,Q9UIQ6,O95817,Q9278...
Processes and pathways
GO Biological process
msigdb_gobp
1,507,508,5,10,525,16,17,18,518,537,22,23,541,27,28,29,532,538,36,555,38,553,550,48,52,564,55,58,61,63,68,577,73,602,601,600,83,591,93,94,98,615,109,607,118,652,648,123,647,645,127,644,631,160,162,173,174,178,177,199,203,206,212,218,236,232,241,242,243,255,257,270,284,294,295,297,309,335,349,348,360,374,372,386,382,405...
1877,1047,1245,348,1507,449,23,2022,2916,507,2949,973,481,1180,450,1334,2278,532,591,177,828,1015,2243,61,349,451,518,3305,2713,178,2024,1979,746,382,1619,1212,3222,1934,160,2508,2333,2114,939,2774,257,1737,2920,1017,607,3107,1935,2070,2974,631,1739,3086,508,218,747,2975,83,199,2921,2421,942,1215,2661,3394,28,3374,1253...
-0.17295227049199338,0.24683554898475726,0.13795385554330206,0.960422918089989,0.005825797498945741,0.7964590939601568,4.034961034471749,-0.2407940247307806,-0.8007005664586212,0.7136086745095508,-0.8247434043522426,0.2900854648262104,0.7551076998175745,0.181637747133562,0.7964590939601568,0.09409221622687368,-0.377842...
3,424
Innate immune system
52
298
3.692106
0.000222
Q9BTY2,P10253,Q9UL46,Q9NZQ3,P49721,P10619,Q9NYB9,P53396,Q8IV08,P05067,P20618,P46108,P42785,Q9NQR4,P28072,P09601,P62993,Q9NQX7,O00584,Q13510,Q92530,P28070,P17900,P16278,Q9UQB8,P49720,Q16539,P30519,P15586,P25788,P20340,P30153,Q92820,Q96F07,O60443,Q9Y376,P07602,P14174,P30154,P07384,O00560,P06280,O15260,O75874,P10321,P1295...
Processes and pathways
Reactome Pathways
msigdb_reactome
260,383,405,402,16,17,273,394,20,392,22,275,25,419,27,28,290,292,159,38,427,48,174,297,51,52,311,58,436,438,437,318,321,323,69,201,72,327,202,326,449,83,88,336,337,219,227,348,222,360,372,386
1506,2414,348,2063,2202,1878,1507,449,1976,159,3124,1179,2022,1558,222,2740,2469,1377,2710,88,1334,1734,1016,69,1210,1090,3250,1735,1789,1473,746,336,2660,1137,562,3355,631,2544,747,2804,592,1936,392,83,798,1838,2921,326,871,72,2421,1476,942,1740,1215,3252,1216,28,1253,2160,1511,383,337,17,2422,1887,1656,573,1982,219,1...
0.005825797498945741,-0.44706992532335543,0.960422918089989,-0.2635077801131671,-0.33195382206434965,-0.17295227049199338,0.005825797498945741,0.7964590939601568,-0.21813043469859994,1.633560379075999,-0.9947882430073097,0.181637747133562,-0.2407940247307806,-0.016355813998760512,1.3213456371291301,-0.6577009942583693,...
3,424
Proteolysis
111
408
3.690851
0.000224
O14965,Q9UHG3,Q92990,Q13098,P49721,P10619,P46379,O75150,Q13042,Q9HB40,P20618,O14773,Q9Y3D6,P42785,Q9GZP9,P28072,Q96KB5,Q15392,Q9H9H4,Q9BRG1,Q5T4S7,Q9NR28,P28070,P49720,Q9Y6J9,Q4ZIN3,Q9H3G5,Q8NBM8,P31749,Q9UJX4,Q9UBS8,Q9NWU2,O43633,P04080,P42892,Q92688,P54727,Q9UIQ6,P19474,Q92783,Q9NQ11,Q8NCM8,Q99816,Q9H2J4,Q5JRX3,Q96J0...
Processes and pathways
GO Biological process
msigdb_gobp
507,10,525,523,16,17,18,518,537,21,22,23,543,25,541,27,538,35,555,553,550,46,48,52,54,63,64,68,577,602,601,600,591,592,93,622,615,109,611,118,652,121,648,123,122,647,127,645,636,637,143,663,152,160,173,178,191,203,204,206,218,230,236,232,241,243,248,246,255,259,284,294,305,304,296,309,321,323,329,330,326,335,348,360,37...
1877,1047,348,2277,1421,1507,449,1976,152,23,2022,507,2949,973,1180,450,3056,1334,1508,2278,591,828,1015,451,425,518,1132,3001,2713,178,1884,1473,746,382,2506,1619,296,1212,3222,1934,160,2508,2114,939,2774,1737,2920,1017,483,2543,1622,218,592,2805,3033,392,981,2744,1838,2921,326,1215,1216,3374,1560,1253,1511,17,3337,12...
-0.17295227049199338,0.24683554898475726,0.960422918089989,-0.37784236620718575,0.05005036958872716,0.005825797498945741,0.7964590939601568,-0.21813043469859994,1.710430973720052,4.034961034471749,-0.2407940247307806,0.7136086745095508,-0.8247434043522426,0.2900854648262104,0.181637747133562,0.7964590939601568,-0.92153...
3,424
Protein catabolic process
76
283
3.262679
0.001104
O14965,Q5TDH0,O75844,Q9NUJ1,Q9UL46,Q9UHG3,Q92990,P49721,P10619,P46379,O75150,Q13042,P20618,O14773,Q9GZP9,Q9Y5A7,Q9NWW5,P28072,Q9UBV2,P50897,Q96KB5,Q9UMX1,O94888,Q13619,Q8N511,Q9H9H4,Q9UN37,Q9BRG1,Q5T4S7,Q9H000,Q9UPT9,Q96RU2,Q92530,P28070,O75503,P49720,P60033,Q05086,P25788,O60502,Q4ZIN3,Q8NBM8,P31749,Q96K76,P49840,Q9UPU...
Processes and pathways
GO Biological process
msigdb_gobp
507,255,382,5,405,10,525,16,17,18,518,537,22,23,541,423,420,27,284,29,538,422,160,410,36,555,294,553,550,429,431,173,427,48,178,52,564,309,438,61,63,68,577,203,454,206,335,602,601,600,212,449,591,451,455,450,372,218,476,468,348,615,236,481,109,516,607,123,241,360,118,652,374,648,647,127
1877,1047,348,1507,449,23,2022,507,2949,973,481,1180,450,1334,2278,591,828,1015,2243,61,451,518,3305,2713,178,1979,746,382,1619,1212,3222,1934,160,2508,2114,939,2774,1737,2920,1017,607,2070,218,2921,942,1215,2661,1511,17,2422,1050,2590,1623,1338,692,2206,1893,2026,1698,22,2547,2027,1843,1218,1430,438,1624,801,3090,2981...
-0.17295227049199338,0.24683554898475726,0.960422918089989,0.005825797498945741,0.7964590939601568,4.034961034471749,-0.2407940247307806,0.7136086745095508,-0.8247434043522426,0.2900854648262104,0.7551076998175745,0.181637747133562,0.7964590939601568,0.09409221622687368,-0.37784236620718575,0.5882077210962579,0.3760787...
3,424
Proteasome core complex
9
15
3.224083
0.001264
Q92530,P49721,P28070,P28074,P49720,P20618,P25788,P28072,P60900
Localization
GO Cellular component
msigdb_gocc
427,16,48,360,52,22,438,27,372
2022,22,1218,1430,438,1624,2164,48,27,360,52,16,372,427,476
-0.2407940247307806,4.148768657849973,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.9203437107781864,0.9400513873986381,2.9191525006451595,4.3099838015719305,0.919644855040064,0.837664611002722,0.7758017403186099
3,424
Nucleophile aminohydrolases, N-terminal [IPR029055]
10
18
3.164965
0.001551
P49721,P28070,P28074,Q9UJ14,P49720,Q99436,P20618,P25788,P28072,P60900
Sequence
InterPro Superfamily
interpro_homologous_superfamily
16,48,360,478,52,476,22,438,27,372
2022,908,22,1218,1430,438,1624,2164,48,27,360,52,16,372,500,1106,476,478
-0.2407940247307806,0.3331658073536866,4.148768657849973,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.9203437107781864,0.9400513873986381,2.9191525006451595,4.3099838015719305,0.919644855040064,0.7343767520911487,0.22514629396294272,0.77580174...
3,424
Proteasome, subunit alpha/beta [IPR001353]
8
14
3.096319
0.001959
P49721,P28070,P28074,P49720,P20618,P25788,P28072,P60900
Sequence
InterPro Family
interpro_family
16,48,360,52,22,438,27,372
2022,22,1218,1430,438,1624,2164,48,27,360,52,16,372,476
-0.2407940247307806,4.148768657849973,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.9203437107781864,0.9400513873986381,2.9191525006451595,4.3099838015719305,0.919644855040064,0.7758017403186099
3,424
Ciliopathy
8
15
3.042242
0.002348
Q9UBB4,O43924,O75665,Q9NQ48,Q8NCM8,Q96J42,Q2M1P5,Q9Y366
Drugs and Diseases
Protein Atlas Disease involvement
protein_atlas_disease_involvement
324,6,75,345,121,154,283,230
6,75,1901,1795,2289,283,924,121,2228,154,1165,345,324,422,230
5.230946559358793,2.491737723101825,-0.17295227049199338,-0.12797037315711082,-0.37784236620718575,1.1422242106360714,0.3331658073536866,1.919509338236697,-0.33195382206434965,1.710430973720052,0.20341379061973036,0.9807596484937686,1.041563022458305,0.8582132041046714,1.3213456371291301
3,424
Vesicle mediated transport
130
389
3.038117
0.002381
P24390,Q99523,Q96A65,Q6NUQ1,Q9BZG1,O15027,P09601,P50897,P04083,Q5VW38,Q9UPN3,Q9H5V9,Q9BRG1,Q9Y282,Q14108,Q14185,O00429,P60033,O95721,P51809,Q9H223,Q96KP1,Q5KU26,Q15436,Q14203,P35606,P55899,Q8WTV0,P20645,P11717,O95070,P30511,P41440,O43633,O15260,Q9Y3B3,Q8WUH2,O14579,O15498,O95249,P09496,Q96ED9,Q08380,P31751,Q92783,O1511...
Processes and pathways
GO Biological process
msigdb_gobp
8,528,526,13,540,531,28,29,534,34,558,554,553,40,43,547,50,564,562,580,589,587,584,583,582,579,71,73,574,573,572,79,80,591,88,90,621,603,604,606,609,115,116,612,118,119,120,642,653,652,648,645,127,128,639,663,656,156,683,672,178,186,189,187,188,195,694,742,211,209,743,726,227,713,721,236,763,760,237,762,764,755,787,789...
2061,3297,1047,2414,2619,2062,2277,50,1975,187,449,713,603,1376,1013,2151,1879,424,480,2803,531,119,2740,188,1247,1881,88,2950,1787,604,865,591,1615,358,1378,1616,829,495,2243,195,867,1424,1299,770,1090,451,1735,1132,3305,831,178,1979,2588,772,907,2155,1137,1335,572,325,3386,606,3031,237,1140,1695,2775,562,2474,1622,53...
-0.2635077801131671,-1.370191822460456,0.24683554898475726,-0.44706992532335543,-0.563529563299227,-0.2635077801131671,-0.37784236620718575,3.0414693740755707,-0.21813043469859994,1.4784190954924807,0.7964590939601568,0.46141133808147106,0.567173303638535,0.07209397481136083,0.26848184419129456,-0.3090872955507271,-0.1...
3,424
Glycosphingolipid metabolism
8
17
2.992004
0.002772
Q13510,P07602,P06865,P17900,P10619,P16278,P06280,P04062
Processes and pathways
Reactome Pathways
msigdb_reactome
38,72,199,174,17,297,83,218
2061,1734,218,83,199,72,2421,17,2627,297,174,38,1276,2316,2109,447,1288
-0.2635077801131671,-0.10555213356065785,1.3607996071828967,2.364601168986997,1.4197473302479848,2.5638712145130462,-0.44706992532335543,4.293933389672934,-0.563529563299227,1.081928208414756,1.556226269579704,3.436429572057339,0.13795385554330206,-0.37784236620718575,-0.2635077801131671,0.8170799788766236,0.1379538555...
3,424
Transporters
108
417
2.900633
0.003724
P24390,Q99523,P45880,Q96A65,O95067,Q9GZP9,Q96N66,P04083,O15397,Q8WY22,Q5VW38,Q9UPN3,Q8N511,Q9UIA9,Q9NPI6,Q14108,O00429,P60033,Q96H78,O95373,Q9UGP8,O43772,Q96KP1,Q15629,O60443,P33176,P07602,Q8WTV0,P31749,P20645,Q5T1Q4,Q8IXU6,P11717,P41440,Q9NQZ5,Q9H061,Q70HW3,P55060,O15260,P04080,Q9Y3B3,Q9Y619,O15118,Q8IYI6,P46934,Q1590...
Functions
Protein Atlas Protein class
protein_atlas_protein_class
8,528,11,526,520,541,539,534,32,552,34,558,36,557,556,43,50,564,55,561,590,62,587,65,69,578,72,73,577,574,76,77,573,80,599,598,85,594,88,592,90,103,119,120,127,128,134,137,136,140,141,146,149,156,165,169,170,185,189,187,188,190,192,194,197,216,217,231,237,238,240,244,251,254,266,271,277,284,287,305,317,335,353,365,358,...
2061,1506,2414,1297,216,317,3279,50,187,1246,449,1976,825,1471,1013,1786,2151,424,1558,973,119,2740,188,1881,88,194,32,1787,2153,1422,1734,1615,358,62,3384,1016,433,3336,495,69,2243,266,867,2659,1090,451,434,3159,271,830,1132,2244,1211,831,2713,1134,976,1473,382,2506,772,1212,2373,217,2508,1137,1335,520,407,1692,3031,2...
-0.2635077801131671,0.005825797498945741,-0.44706992532335543,0.11604540672639355,1.3607996071828967,1.041563022458305,-1.29383678814907,3.0414693740755707,1.4784190954924807,0.13795385554330206,0.7964590939601568,-0.21813043469859994,0.3760787952122493,0.02796108394866905,0.26848184419129456,-0.12797037315711082,-0.30...
3,424
Glycolipid binding
6
12
2.861566
0.004216
Q92643,P07602,O14773,Q9UM22,Q9NWW5,P50897
Functions
GO Molecular function
msigdb_gomf
329,72,23,151,420,29
23,1508,72,29,1666,1631,329,664,420,447,1288,151
4.034961034471749,0.005825797498945741,2.5638712145130462,3.8874444421871313,-0.060859328716587474,-0.038584078694405555,1.0213295041577581,0.5249872346920021,0.8582132041046714,0.8170799788766236,0.13795385554330206,1.7295772862487144
3,424
Membrane lipid catabolic process
6
12
2.798135
0.00514
Q13510,P06865,P17900,P06280,P04062,P50897
Processes and pathways
GO Biological process
msigdb_gobp
38,199,174,83,218,29
257,218,747,83,199,2421,174,29,2127,38,2532,2109
1.2221566892069582,1.3607996071828967,0.4401392201015447,2.364601168986997,1.4197473302479848,-0.44706992532335543,1.556226269579704,3.8874444421871313,-0.28627207679535516,3.436429572057339,-0.4934895964790902,-0.2635077801131671
3,424
Ciliopathies
8
20
2.784323
0.005364
Q9UBB4,O43924,O75665,Q15555,Q9NQ48,Q8NCM8,Q2M1P5,Q9Y366
Processes and pathways
WikiPathways
msigdb_wp
324,6,75,299,345,121,283,230
6,75,2588,1901,1795,1189,299,283,924,121,2357,1073,2228,1460,1165,345,1771,324,422,230
5.230946559358793,2.491737723101825,-0.5401275987389138,-0.17295227049199338,-0.12797037315711082,0.181637747133562,1.081928208414756,1.1422242106360714,0.3331658073536866,1.919509338236697,-0.40086518058570175,0.24683554898475726,-0.33195382206434965,0.05005036958872716,0.20341379061973036,0.9807596484937686,-0.105552...
3,424
Glycosaminoglycan metabolism
10
16
2.765952
0.005676
P54802,Q9Y2C2,P06865,O43505,P16278,Q7LGA3,Q8NCH0,P15586,O75330,Q8TB61
Processes and pathways
Reactome Pathways
msigdb_reactome
162,628,199,110,297,312,247,436,533,165
605,110,533,199,2421,436,297,162,312,247,165,1957,892,931,1467,628
0.567173303638535,1.9759583314382345,0.6719602277437084,1.4197473302479848,-0.44706992532335543,0.8170799788766236,1.081928208414756,1.633560379075999,1.0617625266045119,1.2619281004663285,1.633560379075999,-0.19551663880491682,0.3546430838828725,0.3331658073536866,0.05005036958872716,0.567173303638535
3,424
Sphingolipid metabolism
7
12
2.720504
0.006518
Q13510,O95470,P16278,Q9NRA0,P06280,Q06136,P04062
Processes and pathways
KEGG Pathways
msigdb_kegg
38,257,297,279,83,53,218
406,863,1734,257,218,83,2627,297,53,38,279,2109
0.8582132041046714,0.3546430838828725,-0.10555213356065785,1.2221566892069582,1.3607996071828967,2.364601168986997,-0.563529563299227,1.081928208414756,2.9015948909266185,3.436429572057339,1.162256484953967,-0.2635077801131671
3,424
Macromolecule catabolic process
101
435
2.697735
0.006981
O14965,Q9NUJ1,Q9BRJ7,Q9UHG3,Q92990,P49721,P10619,P46379,O75150,Q13042,P20618,O14773,Q9GZP9,Q12972,P28072,P50897,Q96KB5,Q8N511,Q9NPI6,Q9H9H4,Q9BRG1,Q5T4S7,P28070,P49720,P60033,O60502,Q4ZIN3,Q8NBM8,P31749,Q9UJX4,Q9UBS8,Q9NWU2,O43633,Q9UIV1,P54727,Q9UIQ6,O95817,P35637,Q92783,Q9NQ11,Q99816,Q9H2J4,Q96J02,P46934,Q6PGP7,O9488...
Processes and pathways
GO Biological process
msigdb_gobp
507,5,529,10,525,16,17,18,518,537,22,23,541,536,27,29,538,36,556,555,553,550,48,52,564,61,63,68,577,602,601,600,591,627,615,109,607,613,118,652,648,123,647,127,129,160,162,159,173,178,203,206,207,212,218,236,241,242,255,281,284,294,297,311,310,309,326,335,348,360,374,372,385,383,382,405,399,423,420,422,410,429,431,427,...
1877,3297,1047,712,2683,348,1296,1507,449,159,23,2022,507,2949,973,481,1180,450,2620,1334,2278,591,828,1015,2243,61,1379,451,3000,425,518,714,3305,2713,178,1133,1979,1091,746,382,1619,1212,3222,1934,160,2508,2114,939,2774,2157,1737,2920,1017,607,483,2070,218,747,2115,798,3328,2921,326,942,2977,1510,1215,2661,982,1511,3...
-0.17295227049199338,-1.370191822460456,0.24683554898475726,0.46141133808147106,-0.6105016501849625,0.960422918089989,0.11604540672639355,0.005825797498945741,0.7964590939601568,1.633560379075999,4.034961034471749,-0.2407940247307806,0.7136086745095508,-0.8247434043522426,0.2900854648262104,0.7551076998175745,0.1816377...
3,424
Ceramide metabolic process
13
22
2.67022
0.00758
Q9Y5P4,Q13510,O95470,Q96G23,P27544,P06865,P17900,Q9NRA0,P06280,Q9NWW5,P04062,P30153,Q8NCC3
Processes and pathways
GO Biological process
msigdb_gobp
390,38,257,235,41,199,174,279,83,420,218,318,94
406,863,2278,257,218,83,199,2421,174,41,318,2127,783,38,3322,94,235,2855,279,420,2109,390
0.8582132041046714,0.3546430838828725,-0.37784236620718575,1.2221566892069582,1.3607996071828967,2.364601168986997,1.4197473302479848,-0.44706992532335543,1.556226269579704,3.3854955828676463,1.041563022458305,-0.28627207679535516,0.41882659805980604,3.436429572057339,-1.4472216526588777,2.2178551379904987,1.3015715055...
3,424
Abnormality of corneal stroma
6
13
2.661776
0.007773
Q13510,P34913,O43505,P10619,P16278,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
38,9,110,17,297,218
110,977,218,17,297,693,1051,9,2692,38,395,1068,2585
1.9759583314382345,0.2900854648262104,1.3607996071828967,4.293933389672934,1.081928208414756,0.48264321009370525,0.24683554898475726,4.737605762722128,-0.6105016501849625,3.436429572057339,0.8787259698108449,0.24683554898475726,-0.5167810898411407
3,424
Postaxial hand polydactyly
6
16
2.651512
0.008013
O43924,O75665,Q9NQ48,Q8NCM8,Q96J42,Q2M1P5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
6,75,345,121,154,283
1878,6,75,977,2547,1189,412,283,121,2228,154,1165,345,2739,2464,969
-0.17295227049199338,5.230946559358793,2.491737723101825,0.2900854648262104,-0.5167810898411407,0.181637747133562,0.8582132041046714,1.1422242106360714,1.919509338236697,-0.33195382206434965,1.710430973720052,0.20341379061973036,0.9807596484937686,-0.634072683389437,-0.44706992532335543,0.3116466929225735
3,424
Sphingolipid pathway
7
10
2.638406
0.00833
Q9Y5P4,Q13510,O95470,Q96G23,Q9NRA0,Q06136,P04062
Processes and pathways
WikiPathways
msigdb_wp
390,38,257,235,279,53,218
406,863,257,218,2553,53,38,235,279,390
0.8582132041046714,0.3546430838828725,1.2221566892069582,1.3607996071828967,-0.5167810898411407,2.9015948909266185,3.436429572057339,1.3015715055637238,1.162256484953967,0.899203117641851
3,424
Ph reduction
6
16
2.630269
0.008532
Q8N511,O95295,O75503,P51790,Q05086,P50897
Processes and pathways
GO Biological process
msigdb_gobp
36,237,178,209,309,29
178,1473,237,2249,29,2746,209,1711,309,36,960,3051,420,1010,970,1374
1.536819206241532,0.02796108394866905,1.281765717122395,-0.35487204702297914,3.8874444421871313,-0.6577009942583693,1.380479780604367,-0.08318190024103854,1.0617625266045119,3.5040788567118537,0.3116466929225735,-0.8972415006372373,0.8582132041046714,0.2900854648262104,0.3116466929225735,0.09409221622687368
3,424
Preaxial polydactyly
7
17
2.620367
0.008784
O96028,O43924,O75665,Q9BXW9,Q8NCM8,Q96J42,Q2M1P5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
223,6,75,315,121,154,283
6,2972,75,1692,223,2547,1795,1805,2786,283,675,121,2357,2228,154,315,404
5.230946559358793,-0.8488474856419721,2.491737723101825,-0.08318190024103854,1.3213456371291301,-0.5167810898411407,-0.12797037315711082,-0.12797037315711082,-0.6813870542756404,1.1422242106360714,0.5038350914439771,1.919509338236697,-0.40086518058570175,-0.33195382206434965,1.710430973720052,1.0617625266045119,0.87872...
3,424
Sphingolipid metabolism overview
6
8
2.578574
0.009921
Q13510,O95470,Q96G23,P27544,Q9NRA0,Q06136
Processes and pathways
WikiPathways
msigdb_wp
38,257,235,41,279,53
406,863,257,41,53,38,235,279
0.8582132041046714,0.3546430838828725,1.2221566892069582,3.3854955828676463,2.9015948909266185,3.436429572057339,1.3015715055637238,1.162256484953967
3,424
Sphingolipid metabolism integrated pathway
6
8
2.578574
0.009921
Q13510,O95470,Q96G23,P27544,Q9NRA0,Q06136
Processes and pathways
WikiPathways
msigdb_wp
38,257,235,41,279,53
406,863,257,41,53,38,235,279
0.8582132041046714,0.3546430838828725,1.2221566892069582,3.3854955828676463,2.9015948909266185,3.436429572057339,1.3015715055637238,1.162256484953967
3,424
Intracellular protein transport
84
354
2.575229
0.010017
Q99523,O60830,Q99595,P10619,P46379,Q9Y3D6,Q9GZP9,O15027,Q9NS69,O15397,Q9UIA9,Q9H9H4,Q9BRG1,Q9Y282,Q14108,P60033,O95373,Q9UGP8,Q15629,Q15436,P35606,P33176,P31749,P20645,P55060,O15260,Q9Y3B3,Q8WUH2,Q92688,O95817,P09496,P31751,Q92783,Q7Z3T8,Q9Y584,Q5JRX3,P46934,Q15904,O95429,Q9UHB9,Q8TEX9,P43307,O14737,Q92973,Q5BJH7,Q9UEU...
Processes and pathways
GO Biological process
msigdb_gobp
528,14,15,17,18,543,541,531,30,32,557,555,553,40,43,564,561,590,65,583,579,578,577,574,594,88,90,621,622,607,609,612,118,642,124,122,127,128,133,137,140,145,152,185,186,189,192,195,197,215,228,236,232,237,246,251,254,271,282,284,294,306,311,317,333,343,369,365,358,379,422,407,432,424,444,437,454,449,493,488,483,503,502...
1506,2467,937,2619,2062,317,1878,1246,449,1376,152,1786,1298,424,973,531,88,32,2950,2278,1422,1509,1734,1615,358,828,1016,195,1618,1299,770,14,271,2067,714,1132,1211,831,3001,1134,2373,2660,2155,1137,1335,2069,407,237,561,2774,496,133,1140,1695,2920,2474,607,483,2475,3032,3033,3002,2204,981,3328,942,1215,2865,609,773,1...
0.005825797498945741,-0.4702526844419851,0.3116466929225735,-0.563529563299227,-0.2635077801131671,1.041563022458305,-0.17295227049199338,0.13795385554330206,0.7964590939601568,0.07209397481136083,1.710430973720052,-0.12797037315711082,0.11604540672639355,0.837664611002722,0.2900854648262104,0.6719602277437084,2.309754...
3,424
Genes related to primary cilium development based on crispr
8
16
2.567335
0.010248
Q9Y496,A0AVF1,O75665,Q9C0F1,Q9NQ48,Q8NCM8,Q96J42,Q9Y366
Processes and pathways
WikiPathways
msigdb_wp
465,264,75,428,345,121,154,230
264,75,521,1901,3148,1189,2005,1861,121,2228,154,1165,428,345,230,465
1.202222543915495,2.491737723101825,0.6928032421461253,-0.17295227049199338,-1.0193362784918323,0.181637747133562,-0.21813043469859994,-0.15043696777405058,1.919509338236697,-0.33195382206434965,1.710430973720052,0.20341379061973036,0.837664611002722,0.9807596484937686,1.3213456371291301,0.7964590939601568
3,424
Abnormal midbrain morphology
6
10
2.563459
0.010364
O43924,O75665,P04062,Q2M1P5,Q99700,Q9UMX1
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
6,75,218,283,416,422
6,75,218,1901,1189,1395,283,587,416,422
5.230946559358793,2.491737723101825,1.3607996071828967,-0.17295227049199338,0.181637747133562,0.07209397481136083,1.1422242106360714,0.6092033840492858,0.8582132041046714,0.8582132041046714
3,424
Preaxial hand polydactyly
6
11
2.559412
0.010485
O96028,O75665,Q9BXW9,Q8NCM8,Q96J42,Q2M1P5
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
223,75,315,121,154,283
75,1692,223,1805,2786,283,121,2228,154,315,404
2.491737723101825,-0.08318190024103854,1.3213456371291301,-0.12797037315711082,-0.6813870542756404,1.1422242106360714,1.919509338236697,-0.33195382206434965,1.710430973720052,1.0617625266045119,0.8787259698108449
3,424
Hydrolase activity hydrolyzing o glycosyl compounds
10
21
2.552658
0.01069
Q9BTY2,P54802,Q9NUJ1,P06865,O60476,P17900,P16278,P06280,P04062,O60502
Functions
GO Molecular function
msigdb_gomf
260,162,5,199,265,174,297,83,218,61
3124,265,61,218,747,83,199,2421,383,297,174,912,162,1223,3067,2928,1109,1031,260,5,901
-0.9947882430073097,1.202222543915495,2.742612012191105,1.3607996071828967,0.4401392201015447,2.364601168986997,1.4197473302479848,-0.44706992532335543,0.899203117641851,1.081928208414756,1.556226269579704,0.3331658073536866,1.633560379075999,0.15981786831336206,-0.9215325151651991,-0.8007005664586212,0.225146293962942...
3,424
Chromosome organization involved in meiotic cell cycle
6
16
2.547266
0.010857
Q92791,Q9BTX1,P46379,Q9BXW9,O60566,O94901
Processes and pathways
GO Biological process
msigdb_gobp
96,141,18,315,82,217
2541,82,217,1139,318,18,2289,1670,1026,1191,96,2400,3343,141,315,685
-0.5167810898411407,2.3828349260225634,1.3607996071828967,0.20341379061973036,1.041563022458305,4.2134453698534955,-0.37784236620718575,-0.060859328716587474,0.26848184419129456,0.181637747133562,2.1809212497659063,-0.42394089641202054,-1.5249467943797181,1.8058814249274169,1.0617625266045119,0.5038350914439771
3,424
Lysosomal lumen
16
37
2.545514
0.010912
P54802,O00584,Q8NHP8,Q13510,P07602,P06865,Q14108,P11117,P10619,P17900,P06280,Q8IV08,O14773,Q9UM22,Q9UMR5,P50897
Localization
GO Cellular component
msigdb_gocc
162,159,99,38,72,199,43,144,17,174,83,20,23,151,60,29
159,3124,23,1734,218,747,83,199,72,2421,942,383,17,144,2422,1050,2627,436,297,174,718,3396,946,29,162,1103,38,43,20,2646,99,1642,2317,652,1288,151,60
1.633560379075999,-0.9947882430073097,4.034961034471749,-0.10555213356065785,1.3607996071828967,0.4401392201015447,2.364601168986997,1.4197473302479848,2.5638712145130462,-0.44706992532335543,0.3116466929225735,0.899203117641851,4.293933389672934,1.7677852998342927,-0.44706992532335543,0.24683554898475726,-0.5635295632...
3,424
Regulation of blood pressure
7
21
2.543898
0.010962
Q9UIQ6,Q9NZ08,Q9HB40,P42785,P09601,P42892,P20020
Processes and pathways
GO Biological process
msigdb_gobp
109,243,21,25,28,93,190
1473,3327,2589,289,28,1938,190,2428,25,93,454,2079,2442,2093,885,1957,929,21,243,109,1046
0.02796108394866905,-1.4730517327713326,-0.5401275987389138,1.102060257872399,3.9039025688608877,-0.19551663880491682,1.4588922343866129,-0.44706992532335543,3.969565815164813,2.236284582069333,0.7964590939601568,-0.2635077801131671,-0.44706992532335543,-0.2635077801131671,0.3546430838828725,-0.19551663880491682,0.3331...
3,424
Importin-beta, N-terminal domain [IPR001494]
7
13
2.538218
0.011142
O15397,Q9UIA9,Q9HAV4,Q8TEX9,O95373,Q92973,O00410
Sequence
InterPro Domain
interpro_domain
32,557,197,140,561,185,317
317,1786,973,32,1422,561,594,1950,140,185,815,197,557
1.041563022458305,-0.12797037315711082,0.2900854648262104,3.7717569612772848,0.05005036958872716,0.6301605319345253,0.5882077210962579,-0.19551663880491682,1.8058814249274169,1.5173824255526822,0.39747321103052097,1.4393350324266097,0.6510794016803779
3,424
Cell cycle
80
311
2.515028
0.011902
O14965,P00374,Q15691,P04350,O95684,P49721,O95067,Q13042,P20618,O43805,O75330,P28072,Q7Z5K2,P28070,P49720,Q8NBT2,Q86XL3,Q14203,P31749,P28340,O75665,P41440,Q9UJX4,O60566,O43633,Q9NR33,Q9Y619,P04818,P31751,P15927,Q9BRT9,Q8WUX9,P31350,P61289,P84243,Q9BTX1,Q9NTJ3,Q9UQ84,P56282,Q9H3R5,Q96IY1,Q92973,O14974,Q8NFH5,O60934,Q9Y6X...
Processes and pathways
Reactome Pathways
msigdb_reactome
507,3,510,509,521,16,520,537,22,24,533,27,551,48,52,566,67,582,577,576,75,80,602,82,591,97,103,608,612,610,649,645,126,637,139,141,685,168,167,710,706,185,687,192,689,198,692,202,208,217,727,221,717,713,223,721,724,766,768,757,294,318,348,366,361,360,372,405,412,427,444,440,438,463,476,484,486,482,501,502
2369,348,2063,1507,713,2022,507,687,973,2620,2242,1334,865,591,2065,24,2685,2541,2917,82,770,3000,689,533,2972,2742,75,1134,746,2418,217,208,520,482,1139,521,2920,2070,223,3,3032,1696,509,3033,608,981,3328,871,942,1215,943,3233,484,1381,1561,1741,610,3317,692,2206,2026,2866,800,2252,1184,1698,22,2807,2208,2924,1843,109...
-0.42394089641202054,0.960422918089989,-0.2635077801131671,0.005825797498945741,0.46141133808147106,-0.2407940247307806,0.7136086745095508,0.48264321009370525,0.2900854648262104,-0.563529563299227,-0.35487204702297914,0.09409221622687368,0.3546430838828725,0.5882077210962579,-0.2635077801131671,3.969565815164813,-0.610...
3,424
Sphingolipid metabolism
15
30
2.490494
0.012757
Q9Y5P4,O15269,Q13510,O95470,P07602,P27544,P06865,Q96G23,P17900,P10619,Q9NRA0,P16278,P06280,Q06136,P04062
Processes and pathways
Reactome Pathways
msigdb_reactome
390,406,38,257,72,41,199,235,174,17,279,297,83,53,218
2061,406,863,1734,3031,257,218,83,199,72,2421,17,2627,297,174,1896,41,697,53,38,2930,1276,235,2316,279,2109,447,1288,3170,390
-0.2635077801131671,0.8582132041046714,0.3546430838828725,-0.10555213356065785,-0.8972415006372373,1.2221566892069582,1.3607996071828967,2.364601168986997,1.4197473302479848,2.5638712145130462,-0.44706992532335543,4.293933389672934,-0.563529563299227,1.081928208414756,1.556226269579704,-0.17295227049199338,3.3854955828...
3,424
Neuromuscular process controlling balance
7
13
2.48502
0.012954
P10253,P49588,P17900,P07196,P05067,O14773,Q8IZL8
Processes and pathways
GO Biological process
msigdb_gobp
383,614,174,393,392,23,443
23,689,392,393,2421,383,174,1747,614,1312,1589,1535,443
4.034961034471749,0.48264321009370525,0.8787259698108449,0.8787259698108449,-0.44706992532335543,0.899203117641851,1.556226269579704,-0.10555213356065785,0.567173303638535,0.11604540672639355,-0.016355813998760512,0.005825797498945741,0.8170799788766236
3,424
Sphingolipid metabolism in senescence
6
11
2.483056
0.013026
O15269,Q13510,Q96G23,P16278,Q06136,P04062
Processes and pathways
WikiPathways
msigdb_wp
406,38,235,297,53,218
406,218,484,297,692,1843,1021,987,53,38,235
0.8582132041046714,1.3607996071828967,0.7551076998175745,1.081928208414756,0.48264321009370525,-0.15043696777405058,0.26848184419129456,0.2900854648262104,2.9015948909266185,3.436429572057339,1.3015715055637238
3,424
Endosomal sorting complex required for transport escrt
6
10
2.448888
0.01433
Q9UN37,Q9H9H4,Q9BRG1,O43633,Q92783,Q99816
Processes and pathways
Reactome Pathways
msigdb_reactome
294,555,553,591,118,648
591,645,118,648,553,555,1415,294,1292,1504
0.5882077210962579,0.54609988969302,1.9383524007346755,0.54609988969302,0.6510794016803779,0.6510794016803779,0.07209397481136083,1.102060257872399,0.13795385554330206,0.02796108394866905
3,424
Spinal cord development
9
13
2.444616
0.014501
Q14203,P18074,O95817,Q9ULW3,Q9UKA9,P07196,Q8NCM8,O75312,Q9UMX1
Processes and pathways
GO Biological process
msigdb_gobp
582,693,607,347,448,393,121,714,422
1614,714,607,2246,393,693,774,582,1535,121,448,347,422
-0.038584078694405555,0.46141133808147106,0.567173303638535,-0.35487204702297914,0.8787259698108449,0.48264321009370525,0.41882659805980604,0.6092033840492858,0.005825797498945741,1.919509338236697,0.8170799788766236,0.9807596484937686,0.8582132041046714
3,424
Proteasome
11
36
2.403185
0.016253
O00231,Q9UL46,Q92530,P49721,P28070,P28074,P49720,P20618,P60900,P28072,P25788
Processes and pathways
KEGG Pathways
msigdb_kegg
348,405,427,16,48,360,52,22,372,27,438
348,2063,1507,2022,1334,2026,22,1218,1430,438,1624,2164,48,27,360,1900,1748,1144,52,16,1523,1311,372,637,1347,1487,2481,727,2388,1025,1531,427,476,1197,405,1554
0.960422918089989,-0.2635077801131671,0.005825797498945741,-0.2407940247307806,0.09409221622687368,-0.2407940247307806,4.148768657849973,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.9203437107781864,0.9400513873986381,-0.17295227049199338,-0.1...
3,424
Molecular function regulator
95
304
2.401575
0.016325
P80303,O43924,Q9H0H5,Q92990,Q13098,O95684,O95067,P10619,Q12972,P04083,Q9NPI6,Q02818,Q14185,O00429,O95373,P55010,Q15436,Q86XL3,P31749,P07602,P43490,P41440,P04080,O95817,Q5JRX3,P46934,P51858,O95429,P61289,Q68EM7,Q9BXI6,O14737,P98170,P53634,P17900,P49770,Q9UEU0,O14974,O94813,P18085,Q9Y376,P30154,Q9P2J5,Q06323,P35269,P6315...
Functions
GO Molecular function
msigdb_gomf
4,6,530,525,523,521,520,17,536,534,556,42,547,50,561,56,583,67,577,72,74,80,592,607,122,127,635,133,637,639,663,152,671,698,174,182,189,687,691,694,201,202,739,727,224,724,760,767,768,755,246,753,254,789,795,794,267,776,811,819,818,816,814,306,307,316,317,318,319,860,857,327,856,842,333,334,343,835,836,837,357,364,361,...
307,1047,316,1296,317,50,1878,1507,1976,152,1471,1013,687,2950,3056,1181,1334,6,1883,495,2587,3251,435,2588,3222,691,520,561,133,2156,521,2920,1017,607,592,534,2805,3033,3002,2204,392,1838,3328,2921,72,941,942,1215,1216,3253,17,267,1337,484,1381,1890,1891,2510,1840,327,1741,174,694,2866,1562,1983,1563,2281,2547,1429,18...
1.0617625266045119,0.24683554898475726,1.041563022458305,0.11604540672639355,1.041563022458305,3.0414693740755707,-0.17295227049199338,0.005825797498945741,-0.21813043469859994,1.710430973720052,0.02796108394866905,0.26848184419129456,0.48264321009370525,-0.8247434043522426,-0.9215325151651991,0.181637747133562,0.09409...
3,424
Glycoside hydrolase superfamily [IPR017853]
7
15
2.394957
0.016622
Q9BTY2,P54802,P06865,P16278,P06280,P04062,O60502
Sequence
InterPro Superfamily
interpro_homologous_superfamily
260,162,199,297,83,218,61
61,218,747,83,199,2421,2978,383,297,912,162,1223,2928,260,2317
2.742612012191105,1.3607996071828967,0.4401392201015447,2.364601168986997,1.4197473302479848,-0.44706992532335543,-0.8488474856419721,0.899203117641851,1.081928208414756,0.3331658073536866,1.633560379075999,0.15981786831336206,-0.8007005664586212,1.2221566892069582,-0.37784236620718575
3,424
Sphingolipid metabolism
6
9
2.378657
0.017376
Q13510,O95470,P07602,P17900,Q06136,P04062
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
38,257,72,174,53,218
406,863,257,218,72,174,53,38,3248
0.8582132041046714,0.3546430838828725,1.2221566892069582,1.3607996071828967,2.5638712145130462,1.556226269579704,2.9015948909266185,3.436429572057339,-1.1930461816246576
3,424
Establishment of protein localization to vacuole
9
17
2.377908
0.017411
Q9UN37,Q9H9H4,Q9BRG1,Q99523,P20645,Q14108,Q7Z3T8,Q92783,P46934
Processes and pathways
GO Biological process
msigdb_gobp
294,555,553,528,574,43,642,118,127
2062,1376,2422,1050,574,127,2746,43,642,118,1459,528,1460,553,555,294,743
-0.2635077801131671,0.07209397481136083,-0.44706992532335543,0.24683554898475726,0.6092033840492858,1.8817423752182278,-0.6577009942583693,3.2831126548908953,0.54609988969302,1.9383524007346755,0.05005036958872716,0.6928032421461253,0.05005036958872716,0.6510794016803779,0.6510794016803779,1.102060257872399,0.461411338...
3,424
Lytic vacuole organization
12
29
2.377489
0.017431
P54802,P10253,Q8N511,Q12768,Q14108,O95295,P11117,O75503,Q96ED9,O14773,P04062,P50897
Processes and pathways
GO Biological process
msigdb_gobp
162,383,36,225,43,237,144,178,115,23,218,29
2062,23,178,1473,237,218,2421,383,144,987,29,2746,162,2125,225,43,2640,36,2528,115,1122,540,665,3051,2889,420,1008,1292,1504
-0.2635077801131671,4.034961034471749,1.536819206241532,0.02796108394866905,1.281765717122395,1.3607996071828967,-0.44706992532335543,0.899203117641851,1.7677852998342927,0.2900854648262104,3.8874444421871313,-0.6577009942583693,1.633560379075999,-0.28627207679535516,1.3213456371291301,3.2831126548908953,-0.56352956329...
3,424
Tchem
49
330
2.376971
0.017455
Q15904,Q13126,Q9BTY2,O95470,P34913,P45880,P10619,Q9NRA0,Q96B36,P42785,P09601,P62993,Q13510,Q02818,P35790,Q03164,P24666,P16278,Q16539,P50750,P30519,P07099,O60502,Q92820,P55899,P14174,Q8WTV0,P43490,P06865,Q96K76,Q13564,P41440,Q16850,P51790,Q9UIF9,O00400,P04062,P42892,P36639,O15111,Q9H7B4,P55786,P53985,Q9UIQ6,Q5BJF2,Q9NZ0...
Drugs and Diseases
Pharos IDG Category
pharos_protein_category
128,1,260,257,9,11,17,279,278,25,28,290,38,42,171,172,298,297,311,183,58,57,61,321,71,327,73,74,199,203,328,80,212,209,87,216,218,93,98,222,106,232,231,109,240,243,246,122,127
1877,216,1975,1976,3124,3375,2893,826,1013,1879,507,480,222,481,1880,406,863,1180,1787,2371,532,1016,2415,61,688,1618,1835,2068,1979,336,2333,482,257,1183,2686,2473,1935,1213,2070,1738,1739,2543,218,747,2975,1696,2805,3033,3002,392,981,452,2744,798,199,57,2335,3357,326,2421,2025,942,1839,1215,908,3394,28,3003,1253,1049...
-0.17295227049199338,1.3607996071828967,-0.21813043469859994,-0.21813043469859994,-0.9947882430073097,-1.8162497635728618,-0.7767184510163954,0.3760787952122493,0.26848184419129456,-0.17295227049199338,0.7136086745095508,0.7551076998175745,1.3213456371291301,0.7551076998175745,-0.17295227049199338,0.8582132041046714,0....
3,424
Neuromuscular process
14
26
2.375762
0.017513
Q8N0X7,Q8IZL8,O60934,P10253,O75844,Q14203,Q7Z406,P17900,P49588,P07196,P05067,O14773,P18887,P04062
Processes and pathways
GO Biological process
msigdb_gobp
256,443,689,383,382,582,701,174,614,393,392,23,245,218
23,689,382,218,392,393,2421,383,174,245,987,1747,614,2079,1312,725,2219,582,1589,1535,701,443,256,1122,1406,1502
4.034961034471749,0.48264321009370525,0.899203117641851,1.3607996071828967,0.8787259698108449,0.8787259698108449,-0.44706992532335543,0.899203117641851,1.556226269579704,1.2619281004663285,0.2900854648262104,-0.10555213356065785,0.567173303638535,-0.2635077801131671,0.11604540672639355,0.46141133808147106,-0.3319538220...
3,424
Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
7
13
2.372718
0.017658
Q9UN37,Q9H9H4,Q9BRG1,O43633,Q92783,Q99816,P46934
Processes and pathways
GO Biological process
msigdb_gobp
294,555,553,591,118,648,127
591,127,645,118,648,553,555,854,1415,294,1292,969,1504
0.5882077210962579,1.8817423752182278,0.54609988969302,1.9383524007346755,0.54609988969302,0.6510794016803779,0.6510794016803779,0.3760787952122493,0.07209397481136083,1.102060257872399,0.13795385554330206,0.3116466929225735,0.02796108394866905
3,424
Regulation of runx3 expression and activity
11
37
2.359709
0.018289
O00231,Q9UL46,Q92530,P49721,P28070,P28074,P49720,P20618,P60900,P28072,P25788
Processes and pathways
Reactome Pathways
msigdb_reactome
348,405,427,16,48,360,52,22,372,27,438
348,2063,1507,2022,1334,746,2026,22,1218,1430,438,1624,2164,48,27,360,1900,1519,1748,1144,52,16,1523,1311,372,637,1347,1487,2481,727,2388,1531,427,476,1197,405,1554
0.960422918089989,-0.2635077801131671,0.005825797498945741,-0.2407940247307806,0.09409221622687368,0.4401392201015447,-0.2407940247307806,4.148768657849973,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.9203437107781864,0.9400513873986381,-0.172...
3,424
Cross presentation of soluble exogenous antigens endosomes
12
38
2.333307
0.019632
O00231,Q9UL46,Q92530,P49721,P28070,P28074,P49720,P20618,P60900,P28072,P25788,Q9UBG0
Processes and pathways
Reactome Pathways
msigdb_reactome
348,405,427,16,48,360,52,22,372,27,438,388
348,2063,1507,2022,1334,746,2026,22,1218,1430,438,1624,2164,48,27,360,1900,1748,1144,52,16,1523,1311,372,637,1347,1487,2481,727,2388,1025,1531,427,476,1197,388,405,1554
0.960422918089989,-0.2635077801131671,0.005825797498945741,-0.2407940247307806,0.09409221622687368,0.4401392201015447,-0.2407940247307806,4.148768657849973,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.9203437107781864,0.9400513873986381,-0.172...
3,424
Protein localization to vacuole
12
23
2.323876
0.020132
Q9UN37,Q9H9H4,Q9BRG1,Q99523,P20645,Q14108,O75116,P60033,Q7Z3T8,Q92783,Q9NUN5,P46934
Processes and pathways
GO Biological process
msigdb_gobp
294,555,553,528,574,43,425,564,642,118,376,127
2062,1376,425,2422,1050,574,127,2746,564,43,642,118,1459,528,1460,553,555,652,2015,376,294,743,1780
-0.2635077801131671,0.07209397481136083,0.837664611002722,-0.44706992532335543,0.24683554898475726,0.6092033840492858,1.8817423752182278,-0.6577009942583693,0.6301605319345253,3.2831126548908953,0.54609988969302,1.9383524007346755,0.05005036958872716,0.6928032421461253,0.05005036958872716,0.6510794016803779,0.651079401...
3,424
Diseases of glycosylation
6
21
2.321242
0.020274
Q96AA3,P06865,O43505,Q9NP73,P10619,Q8NCH0
Processes and pathways
Reactome Pathways
msigdb_reactome
169,199,110,143,17,247
110,1472,1132,199,2421,17,297,2253,2512,1436,1106,3067,3010,1110,247,1957,169,892,1864,143,1611
1.9759583314382345,0.02796108394866905,0.20341379061973036,1.4197473302479848,-0.44706992532335543,4.293933389672934,1.081928208414756,-0.35487204702297914,-0.4934895964790902,0.05005036958872716,0.22514629396294272,-0.9215325151651991,-0.8730133389302461,0.22514629396294272,1.2619281004663285,-0.19551663880491682,1.59...
3,424
Protein localization to lysosome
10
17
2.316943
0.020507
Q9UN37,Q99523,P20645,Q14108,O75116,P60033,Q7Z3T8,Q9NQ11,Q9NUN5,P46934
Processes and pathways
GO Biological process
msigdb_gobp
294,528,574,43,425,564,642,652,376,127
2062,1376,425,2422,1050,574,127,2746,564,43,642,528,652,2015,376,294,743
-0.2635077801131671,0.07209397481136083,0.837664611002722,-0.44706992532335543,0.24683554898475726,0.6092033840492858,1.8817423752182278,-0.6577009942583693,0.6301605319345253,3.2831126548908953,0.54609988969302,0.6928032421461253,0.54609988969302,-0.21813043469859994,0.919644855040064,1.102060257872399,0.4614113380814...
3,424
Degradation of axin
11
37
2.315458
0.020588
O00231,Q9UL46,Q92530,P49721,P28070,P28074,P49720,P20618,P60900,P28072,P25788
Processes and pathways
Reactome Pathways
msigdb_reactome
348,405,427,16,48,360,52,22,372,27,438
348,2063,1507,2022,1334,746,2026,22,1218,1430,438,1624,2164,48,27,360,1900,1748,1144,52,16,1523,1311,372,637,1347,1487,2481,727,2388,1025,1531,427,476,1197,405,1554
0.960422918089989,-0.2635077801131671,0.005825797498945741,-0.2407940247307806,0.09409221622687368,0.4401392201015447,-0.2407940247307806,4.148768657849973,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.9203437107781864,0.9400513873986381,-0.172...
3,424
Hydrolase activity acting on glycosyl bonds
12
29
2.3058
0.021122
Q9BTY2,P54802,Q9NUJ1,P06865,O60476,P17900,O75503,P16278,P06280,Q6SZW1,P04062,O60502
Functions
GO Molecular function
msigdb_gomf
260,162,5,199,265,174,178,297,83,386,218,61
3124,532,265,61,178,218,747,83,199,2421,383,1381,297,174,1742,1515,2028,912,162,2126,1223,3067,2928,1109,386,1031,260,5,901
-0.9947882430073097,0.6719602277437084,1.202222543915495,2.742612012191105,1.536819206241532,1.3607996071828967,0.4401392201015447,2.364601168986997,1.4197473302479848,-0.44706992532335543,0.899203117641851,0.07209397481136083,1.081928208414756,1.556226269579704,-0.10555213356065785,0.005825797498945741,-0.240794024730...
3,424
Sphingolipid metabolic process
18
34
2.304552
0.021192
Q9Y5P4,O15269,Q13510,O95470,P07602,P27544,P06865,Q96G23,P17900,P16278,Q9NRA0,P06280,Q06136,Q9NWW5,P04062,P50897,P30153,Q8NCC3
Processes and pathways
GO Biological process
msigdb_gobp
390,406,38,257,72,41,199,235,174,297,279,83,53,420,218,29,318,94
406,863,2278,257,218,83,199,72,2421,297,174,1896,41,318,29,2127,53,783,38,3322,2930,1494,94,235,2855,279,420,2109,3248,447,1288,1087,3170,390
0.8582132041046714,0.3546430838828725,-0.37784236620718575,1.2221566892069582,1.3607996071828967,2.364601168986997,1.4197473302479848,2.5638712145130462,-0.44706992532335543,1.081928208414756,1.556226269579704,-0.17295227049199338,3.3854955828676463,1.041563022458305,3.8874444421871313,-0.28627207679535516,2.9015948909...
3,424
Degradation of dvl
11
38
2.299498
0.021477
O00231,Q9UL46,Q92530,P49721,P28070,P28074,P49720,P20618,P60900,P28072,P25788
Processes and pathways
Reactome Pathways
msigdb_reactome
348,405,427,16,48,360,52,22,372,27,438
348,2063,1507,2022,1334,746,2026,22,1218,1430,438,1624,2164,48,27,360,1900,1748,1144,52,16,1523,1311,372,637,1347,1487,2481,727,2388,1587,1025,1531,427,476,1197,405,1554
0.960422918089989,-0.2635077801131671,0.005825797498945741,-0.2407940247307806,0.09409221622687368,0.4401392201015447,-0.2407940247307806,4.148768657849973,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.9203437107781864,0.9400513873986381,-0.172...
3,424
Regulation of ras by gaps
11
38
2.299498
0.021477
O00231,Q9UL46,Q92530,P49721,P28070,P28074,P49720,P20618,P60900,P28072,P25788
Processes and pathways
Reactome Pathways
msigdb_reactome
348,405,427,16,48,360,52,22,372,27,438
348,2063,1507,2022,1334,746,2026,22,1218,1430,438,1624,2164,48,27,360,1900,1748,1144,52,16,1523,1311,372,637,1347,1487,2481,727,2388,1587,1025,1531,427,476,1197,405,1554
0.960422918089989,-0.2635077801131671,0.005825797498945741,-0.2407940247307806,0.09409221622687368,0.4401392201015447,-0.2407940247307806,4.148768657849973,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.9203437107781864,0.9400513873986381,-0.172...
3,424
Disproportionate short limb short stature
10
22
2.29948
0.021478
Q14739,O75718,Q32P28,Q15392,Q6DKJ4,P10644,Q03164,Q7LGA3,Q8NCM8,Q9Y366
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
412,288,163,35,200,267,172,312,121,230
2915,1880,2244,288,267,3163,987,1570,172,426,1227,412,658,35,163,200,312,121,1000,2228,2739,230
-0.8007005664586212,-0.17295227049199338,-0.35487204702297914,1.102060257872399,1.202222543915495,-1.0439500146155303,0.2900854648262104,-0.016355813998760512,1.5756037680405113,0.837664611002722,0.15981786831336206,0.8582132041046714,0.5249872346920021,3.6217550428705194,1.633560379075999,1.4197473302479848,1.06176252...
3,424
Aminoglycan metabolic process
9
18
2.277702
0.022744
P54802,O60701,P06865,P15586,O43505,P16278,Q7LGA3,Q8NCH0,Q9NWW5
Processes and pathways
GO Biological process
msigdb_gobp
162,517,199,436,110,297,312,247,420
110,517,2474,747,199,2421,436,297,162,1853,312,247,1957,892,420,1414,931,628
1.9759583314382345,0.6928032421461253,-0.4702526844419851,0.4401392201015447,1.4197473302479848,-0.44706992532335543,0.8170799788766236,1.081928208414756,1.633560379075999,-0.15043696777405058,1.0617625266045119,1.2619281004663285,-0.19551663880491682,0.3546430838828725,0.8582132041046714,0.07209397481136083,0.33316580...
3,424
Intra golgi traffic
7
15
2.260861
0.023768
Q9H9E3,O00461,O15498,O60476,O43752,Q8TBA6,O95721
Processes and pathways
Reactome Pathways
msigdb_reactome
398,104,604,265,358,475,562
104,604,358,265,606,562,2214,1750,1445,2087,1109,475,1002,398,1083
2.0508529552783132,0.567173303638535,0.9400513873986381,1.202222543915495,0.567173303638535,0.6301605319345253,-0.33195382206434965,-0.10555213356065785,0.05005036958872716,-0.2635077801131671,0.22514629396294272,0.7758017403186099,0.2900854648262104,0.8787259698108449,0.24683554898475726
3,424
Hydrolase
79
400
2.242606
0.024922
Q9H6V9,Q9NUJ1,P34913,P10619,Q8IV08,Q9HB40,O14773,P42785,P28072,P50897,Q13510,Q9NTK5,O00429,P07099,Q9UMR5,O60502,Q9H3G5,P06280,P42892,Q8NCC3,P36639,Q8NHP8,Q9UIQ6,Q5JRX3,Q9NP73,P11117,P54802,O00584,Q9UQ84,Q96RU2,P17900,Q15165,P06865,Q96K76,Q9UPU5,P04062,P12956,P55786,Q9BQG2,Q9NZ08,Q96FW1,Q5TDH0,Q9BTY2,P49593,O60476,Q9UN3...
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
2,5,9,17,20,21,23,25,27,29,38,39,50,57,60,61,64,83,93,94,98,99,109,122,143,144,162,159,168,173,174,180,199,203,206,218,219,232,242,243,248,255,260,259,265,294,295,304,298,297,296,321,329,326,349,360,374,386,385,383,382,399,419,411,407,431,436,433,461,458,478,476,474,466,490,501,498,516,514
2682,1933,2709,1245,1421,50,1507,1976,159,713,3124,1731,862,544,23,3158,1248,2621,2278,532,1734,1015,1423,2917,2066,433,265,61,349,771,3001,1979,2332,1091,382,296,466,2333,2114,407,1182,2157,1183,667,2542,3107,1935,508,218,747,83,199,57,326,2421,942,1302,1253,383,1049,17,1790,144,2422,1337,1255,219,1891,1427,3379,1623,...
-0.6105016501849625,-0.19551663880491682,-0.634072683389437,0.13795385554330206,0.05005036958872716,3.0414693740755707,0.005825797498945741,-0.21813043469859994,1.633560379075999,0.46141133808147106,-0.9947882430073097,-0.10555213356065785,0.3546430838828725,0.6510794016803779,4.034961034471749,-1.0439500146155303,0.13...
3,424
Abnormal biliary tract morphology
8
23
2.233626
0.025508
Q9NSD9,P07602,P14174,Q14108,Q13043,Q9NUN5,P04062,P09601
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
293,72,327,43,246,376,218,28
1734,3032,218,72,28,327,2627,1564,2721,2666,1189,246,43,412,2043,1073,647,293,376,1288,859,1829,1178
-0.10555213356065785,-0.8972415006372373,1.3607996071828967,2.5638712145130462,3.9039025688608877,1.0213295041577581,-0.563529563299227,-0.016355813998760512,-0.634072683389437,-0.5869874296794594,0.181637747133562,1.2619281004663285,3.2831126548908953,0.8582132041046714,-0.2407940247307806,0.24683554898475726,0.546099...
3,424
Biliary tract abnormality
9
26
2.225519
0.026046
O96028,Q9NSD9,P07602,P14174,Q14108,Q13043,Q9NUN5,P04062,P09601
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
223,293,72,327,43,246,376,218,28
1734,1692,223,3032,218,72,28,327,2627,1564,2721,2666,1189,246,1805,43,412,2043,1073,647,293,376,1288,859,1829,1178
-0.10555213356065785,-0.08318190024103854,1.3213456371291301,-0.8972415006372373,1.3607996071828967,2.5638712145130462,3.9039025688608877,1.0213295041577581,-0.563529563299227,-0.016355813998760512,-0.634072683389437,-0.5869874296794594,0.181637747133562,1.2619281004663285,-0.12797037315711082,3.2831126548908953,0.8582...
3,424
Metabolism of polyamines
11
39
2.219416
0.026458
O00231,Q9UL46,Q92530,P49721,P28070,P28074,P49720,P20618,P60900,P28072,P25788
Processes and pathways
Reactome Pathways
msigdb_reactome
348,405,427,16,48,360,52,22,372,27,438
348,2063,1507,2022,1334,746,2026,1052,22,1218,1430,438,1624,2164,48,27,360,1900,1748,1144,52,16,1523,1907,1311,372,637,1347,1487,2481,727,2388,1025,1531,427,476,1197,405,1554
0.960422918089989,-0.2635077801131671,0.005825797498945741,-0.2407940247307806,0.09409221622687368,0.4401392201015447,-0.2407940247307806,0.24683554898475726,4.148768657849973,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.9203437107781864,0.940...
3,424
Asymmetric localization of pcp proteins
11
38
2.216731
0.026641
O00231,Q9UL46,Q92530,P49721,P28070,P28074,P49720,P20618,P60900,P28072,P25788
Processes and pathways
Reactome Pathways
msigdb_reactome
348,405,427,16,48,360,52,22,372,27,438
348,2063,1507,2022,1334,746,2026,22,1218,1430,438,1624,2164,48,27,360,1900,1748,1144,52,16,1523,1311,372,637,1347,1487,2481,727,2388,2564,1025,1531,427,476,1197,405,1554
0.960422918089989,-0.2635077801131671,0.005825797498945741,-0.2407940247307806,0.09409221622687368,0.4401392201015447,-0.2407940247307806,4.148768657849973,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.9203437107781864,0.9400513873986381,-0.172...
3,424
Immunoglobulin E-set [IPR014756]
6
17
2.199762
0.027824
O15031,Q9UIW2,O43924,A6NIH7,O14972,Q9UGP8
Sequence
InterPro Superfamily
interpro_homologous_superfamily
166,331,6,107,424,590
107,424,166,6,2244,2332,2547,1339,1055,1103,1223,1949,2570,845,587,590,331
2.0134581825802558,0.837664611002722,1.614270673601803,5.230946559358793,-0.35487204702297914,-0.40086518058570175,-0.5167810898411407,0.09409221622687368,0.24683554898475726,0.22514629396294272,0.15981786831336206,-0.19551663880491682,-0.5167810898411407,0.3760787952122493,0.6092033840492858,0.6092033840492858,1.02132...
3,424
Viral budding
6
11
2.191461
0.028418
Q9UN37,Q9H9H4,O43633,Q99816,Q8WUX9,P46934
Processes and pathways
GO Biological process
msigdb_gobp
294,555,591,648,645,127
591,127,1450,645,648,555,854,1415,294,1292,1504
0.5882077210962579,1.8817423752182278,0.05005036958872716,0.54609988969302,0.54609988969302,0.6510794016803779,0.3760787952122493,0.07209397481136083,1.102060257872399,0.13795385554330206,0.02796108394866905
3,424
Multivesicular body organization
8
13
2.190361
0.028498
Q9HD42,Q9UN37,Q9H9H4,Q9BRG1,O43633,Q92783,Q99816,Q8WUX9
Processes and pathways
GO Biological process
msigdb_gobp
854,294,555,553,591,118,648,645
591,947,1450,645,118,648,553,555,854,1415,294,1292,1504
0.5882077210962579,0.3116466929225735,0.05005036958872716,0.54609988969302,1.9383524007346755,0.54609988969302,0.6510794016803779,0.6510794016803779,0.3760787952122493,0.07209397481136083,1.102060257872399,0.13795385554330206,0.02796108394866905
3,424
Glycosphingolipid metabolic process
6
11
2.188839
0.028609
P06865,P17900,P16278,P06280,Q9NWW5,P04062
Processes and pathways
GO Biological process
msigdb_gobp
199,174,297,83,420,218
218,83,199,2421,297,174,2127,783,2855,420,447
1.3607996071828967,2.364601168986997,1.4197473302479848,-0.44706992532335543,1.081928208414756,1.556226269579704,-0.28627207679535516,0.41882659805980604,-0.7289343410651667,0.8582132041046714,0.8170799788766236
3,424
Scf skp2 mediated degradation of p27 p21
12
41
2.187109
0.028735
O00231,Q9UL46,Q92530,P49721,P28070,P28074,P49720,Q99436,P20618,P60900,P28072,P25788
Processes and pathways
Reactome Pathways
msigdb_reactome
348,405,427,16,48,360,52,476,22,372,27,438
348,2063,1507,2022,1334,746,484,2026,22,1843,1218,1430,438,1624,2164,48,27,360,1900,1748,1144,52,16,1523,1311,372,637,1347,1487,2481,914,727,2388,1225,1390,1531,427,476,1197,405,1554
0.960422918089989,-0.2635077801131671,0.005825797498945741,-0.2407940247307806,0.09409221622687368,0.4401392201015447,0.7551076998175745,-0.2407940247307806,4.148768657849973,-0.15043696777405058,0.15981786831336206,0.05005036958872716,0.8170799788766236,-0.038584078694405555,-0.3090872955507271,3.1455107185880773,3.92...
3,424