term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5
values | subtype stringclasses 24
values | subtype_key stringclasses 24
values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholesterol metabolism with bloch and kandutschrussell pathways | 10 | 25 | 2.60039 | 0.009312 | Q14739,Q16850,P37268,Q15392,P04035,Q14534,P48449,P14324,P35610,O75845 | Processes and pathways | WikiPathways | msigdb_wp | 195,65,68,230,267,172,85,402,122,310 | 3022,1893,310,1589,622,677,267,402,1131,122,68,85,1399,1967,1664,2766,172,195,1541,230,1982,686,65,456,699 | -1.5441372114598413,-0.24230752653304063,0.9688011263013478,-0.09949469747666943,0.4794588708276966,0.429857390182749,1.0990194895203063,0.7657939331769242,0.11989823952072967,2.0009038654063014,2.770727945453716,2.489102096014749,-0.015949191785796384,-0.2714249570573372,-0.12769463103528156,-0.8636557041179473,1.4870... | 3,120 |
Hand polydactyly | 17 | 31 | 2.596465 | 0.009419 | Q14739,Q92890,Q5H8A4,Q9BXW9,Q8IY17,Q15067,O60826,Q9UM00,Q8NCM8,O43924,P21964,Q9H0F7,Q10713,Q13045,Q9UHX1,O00459,O75845 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 195,642,248,693,638,300,391,441,667,79,146,352,55,405,583,339,310 | 339,1698,79,391,310,896,1040,2806,146,1397,1466,870,55,405,2557,195,1980,300,248,638,667,642,2000,693,352,2980,699,583,1111,441,1886 | 0.8797499948322487,-0.1560737352527625,2.610061135094578,0.7888261461963076,0.9688011263013478,0.25170495959874245,0.1730932216945844,-0.9307313466100875,1.733451983355156,-0.015949191785796384,-0.043624015597528217,0.2776008882438347,2.9114638007546514,0.7657939331769242,-0.6363634842619023,1.388303199401113,-0.271424... | 3,120 |
Molecular transducer activity | 7 | 32 | 2.588876 | 0.009629 | Q15629,P20645,Q14108,O15118,Q99720,P30536,Q8WTV0 | Functions | GO Molecular function | msigdb_gomf | 121,165,105,112,20,25,30 | 3099,320,112,1271,1768,3044,1390,1451,165,25,2762,989,1399,807,1347,1724,105,1414,121,1415,959,2938,30,748,1425,20,1165,671,2928,512,673,184 | -2.671736994716146,0.9467099920148521,2.1200791235371135,0.03888935479482263,-0.18463413695639644,-1.7411148495013815,-0.015949191785796384,-0.043624015597528217,1.5451910091391072,3.607914396820148,-0.8636557041179473,0.19945282519176055,-0.015949191785796384,0.32894076142978074,0.011554613903006978,-0.156073735252762... | 3,120 |
Disproportionate short limb short stature | 12 | 20 | 2.569559 | 0.010183 | Q7RTS9,Q14739,O75718,Q6DKJ4,Q15392,Q9UBM7,Q8NCM8,Q7LGA3,P42345,Q32P28,Q96MF7,Q9H6U8 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 196,195,619,394,230,699,667,17,680,366,387,188 | 939,703,2550,619,1273,2464,680,992,1978,195,230,366,394,17,196,667,387,1366,188,699 | 0.22565616698772623,0.4048447144069418,-0.6363634842619023,0.4794588708276966,0.03888935479482263,-0.5734566251984043,0.429857390182749,0.19945282519176055,-0.2714249570573372,1.388303199401113,1.2045970593385245,0.8345267182780652,0.7888261461963076,3.811591163952668,1.388303199401113,0.45472828026538425,0.81173667819... | 3,120 |
Organophosphate ester transport | 9 | 26 | 2.561447 | 0.010424 | Q9H2D1,Q14108,Q8TB61,P41440,O43808,Q99808,Q9NZD2,P08183,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 40,105,369,204,332,242,252,22,30 | 332,1229,22,1079,1335,1905,1963,204,1712,3074,1665,1347,105,2272,1670,369,423,30,3048,242,1213,40,1432,252,2241,585 | 0.9021855262027676,0.06605695177290508,3.744867759885806,0.1465756160978675,0.011554613903006978,-0.24230752653304063,-0.2714249570573372,1.3279431624639007,-0.1560737352527625,-1.9889367176870343,-0.12769463103528156,0.011554613903006978,2.186673620608435,-0.4199119328370344,-0.12769463103528156,0.8345267182780652,0.7... | 3,120 |
Insulin resistance | 9 | 18 | 2.557363 | 0.010547 | P31751,P17096,Q8NC56,O95140,O75844,Q9H0F7,Q96MF7,P28340,O76024 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 570,446,138,429,13,352,387,311,254 | 1326,1265,618,13,254,429,1766,446,1452,311,570,2762,1462,952,138,387,352,1033 | 0.011554613903006978,0.03888935479482263,0.4794588708276966,3.9629821531008274,1.1415631395121968,0.7193596211985692,-0.18463413695639644,0.6959550565518066,-0.043624015597528217,0.9688011263013478,0.5285049852239486,-0.8636557041179473,-0.043624015597528217,0.22565616698772623,1.8782176443063971,0.8117366781974475,0.8... | 3,120 |
HAD superfamily [IPR023214] | 8 | 21 | 2.557129 | 0.010554 | P78330,P35670,Q9HD20,P16615,Q3ZCQ8,Q969T7,Q9H0P0,P49902 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 322,255,136,239,240,50,457,222 | 2457,862,239,447,1706,255,222,322,2436,1469,240,1927,784,689,50,1255,788,457,1814,1319,136 | -0.5734566251984043,0.2776008882438347,1.1836886940989366,0.6959550565518066,-0.1560737352527625,1.1415631395121968,1.2461096037129336,0.9467099920148521,-0.5423276822514903,-0.043624015597528217,1.1836886940989366,-0.24230752653304063,0.3543879449769868,0.429857390182749,2.9664133235537427,0.06605695177290508,0.354387... | 3,120 |
HAD-like superfamily [IPR036412] | 8 | 21 | 2.557129 | 0.010554 | P78330,P35670,Q9HD20,P16615,Q3ZCQ8,Q969T7,Q9H0P0,P49902 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 322,255,136,239,240,50,457,222 | 2457,862,239,447,1706,255,222,322,2436,1469,240,1927,784,689,50,1255,788,457,1814,1319,136 | -0.5734566251984043,0.2776008882438347,1.1836886940989366,0.6959550565518066,-0.1560737352527625,1.1415631395121968,1.2461096037129336,0.9467099920148521,-0.5423276822514903,-0.043624015597528217,1.1836886940989366,-0.24230752653304063,0.3543879449769868,0.429857390182749,2.9664133235537427,0.06605695177290508,0.354387... | 3,120 |
Mitochondrial protein import | 13 | 34 | 2.541404 | 0.011041 | Q5JRX3,O60830,Q9NS69,Q96B49,Q8N4H5,P21796,Q3ZCQ8,O14925,Q9UJS0,Q10713,Q13505,Q9Y512,Q15388 | Processes and pathways | Reactome Pathways | msigdb_reactome | 160,3,35,264,72,16,240,113,411,55,88,459,346 | 113,615,3,2870,618,2458,567,2069,444,1077,766,1507,2802,1079,1335,16,1773,2667,55,88,346,240,160,72,264,2990,1569,35,757,411,1027,459,2833,3105 | 2.1032619844886535,0.4794588708276966,5.022002691408248,-1.033222533253154,0.4794588708276966,-0.5734566251984043,0.5285049852239486,-0.33023269302803204,0.6959550565518066,0.1465756160978675,0.3543879449769868,-0.07147184402573621,-0.9307313466100875,0.1465756160978675,0.011554613903006978,3.844530607020698,-0.1846341... | 3,120 |
Aminoglycan metabolic process | 6 | 16 | 2.540123 | 0.011081 | O43505,Q96L58,P15586,Q7LGA3,Q8NCH0,Q9NX62 | Processes and pathways | GO Biological process | msigdb_gobp | 141,175,238,17,117,224 | 141,1639,2460,1124,2070,2618,591,238,476,276,1405,838,17,117,175,224 | 1.8424923729445961,-0.12769463103528156,-0.5734566251984043,0.11989823952072967,-0.33023269302803204,-0.7001544799726708,0.5040506253802524,1.1836886940989366,0.6487648093812882,1.0775884567819758,-0.015949191785796384,0.30334561141450944,3.811591163952668,2.069421914151396,1.487036333627781,1.2461096037129336 | 3,120 |
Lysosomal lumen | 11 | 33 | 2.533219 | 0.011302 | O14773,P11117,Q9UM22,Q13510,P10619,Q14108,Q8IV08,P17900,P15586,P50897,Q8NHP8 | Localization | GO Cellular component | msigdb_gocc | 66,97,37,71,200,105,232,268,238,48,90 | 2340,66,675,1902,1124,898,2070,2618,1230,591,1593,200,97,1644,3088,238,476,268,500,3016,2084,48,276,3074,71,105,232,2856,90,1257,426,37,2543 | -0.4807050971530273,2.7850237629841788,0.429857390182749,-0.24230752653304063,0.11989823952072967,0.25170495959874245,-0.33023269302803204,-0.7001544799726708,0.06605695177290508,0.5040506253802524,-0.09949469747666943,1.3481584340693418,2.3167291137840786,-0.12769463103528156,-2.2504606922272252,1.1836886940989366,0.6... | 3,120 |
Slc mediated transmembrane transport | 9 | 24 | 2.519969 | 0.011737 | P53985,Q8TB61,Q70HW3,P35613,Q9NY64,Q8TAD4,Q99808,Q9UBX3,P30825 | Processes and pathways | Reactome Pathways | msigdb_reactome | 104,369,110,143,438,208,242,157,126 | 1229,767,2255,1079,1335,2841,126,143,2310,104,626,2672,1415,1732,110,208,369,1010,242,1683,496,438,157,1175 | 0.06605695177290508,0.3543879449769868,-0.4199119328370344,0.1465756160978675,0.011554613903006978,-0.9646412623937256,1.9662172504490403,1.788326470466217,-0.45020613666046194,2.186673620608435,0.4794588708276966,-0.7323887974882097,-0.015949191785796384,-0.1560737352527625,2.1368283516262,1.3076315066448148,0.8345267... | 3,120 |
Phospholipid binding | 18 | 83 | 2.514031 | 0.011936 | O14773,Q9NZJ7,Q9UM22,P45880,Q14108,Q8NCC3,P21796,P50897,Q9H0F7,Q9Y2I1,Q9Y3E7,Q9NZD2,Q9BWH2,Q13045,P53367,Q9Y4G8,O60313,Q8WTV0 | Functions | GO Molecular function | msigdb_gomf | 66,426,37,70,105,11,16,48,352,180,253,252,251,405,245,125,340,30 | 822,2755,1227,66,1379,2063,2249,1443,340,1075,428,3013,1177,799,1389,3055,2345,1232,1591,1644,2757,1045,1127,770,16,1905,1338,2920,1189,70,1191,1286,1712,48,1841,245,1531,1143,405,1198,953,2161,105,1146,2479,2269,552,601,1862,1549,1553,1617,11,2277,30,927,640,1012,928,1311,1748,1626,251,1213,352,1680,694,252,426,3006,2... | 0.30334561141450944,-0.8636557041179473,0.06605695177290508,2.7850237629841788,-0.015949191785796384,-0.33023269302803204,-0.4199119328370344,-0.043624015597528217,0.8797499948322487,0.1465756160978675,0.7193596211985692,-1.5057183812598571,0.09305929398318494,0.32894076142978074,-0.015949191785796384,-1.78152336960664... | 3,120 |
Protein localization | 22 | 70 | 2.513609 | 0.01195 | O60830,Q96B49,P21796,Q9UJS0,Q5JRX3,Q9NS69,P50402,Q15067,P09601,P51648,Q10713,A8MXV4,Q9Y512,Q8N4H5,O95169,O43808,Q9BY49,Q9NR77,Q15388,Q13505,Q3ZCQ8,O14925 | Processes and pathways | Reactome Pathways | msigdb_reactome | 3,264,16,411,160,35,290,300,296,47,55,181,459,72,444,332,467,80,346,88,240,113 | 181,939,113,703,762,615,675,1074,332,3070,3,1704,2870,618,2458,654,567,1179,2069,444,1077,766,1507,3034,296,2802,1079,1335,1274,16,1963,1773,1282,2809,2667,1461,596,290,47,1401,2922,504,55,462,1853,88,300,346,240,160,2768,72,2224,2567,1563,264,2990,467,1569,80,35,757,2241,2608,411,1027,728,459,2833,3105 | 1.4478182777817359,0.22565616698772623,2.1032619844886535,0.4048447144069418,0.3543879449769868,0.4794588708276966,0.429857390182749,0.1465756160978675,0.9021855262027676,-1.9889367176870343,5.022002691408248,-0.1560737352527625,-1.033222533253154,0.4794588708276966,-0.5734566251984043,0.45472828026538425,0.52850498522... | 3,120 |
Mitophagy | 6 | 12 | 2.513608 | 0.01195 | Q9NS69,Q8N4H5,Q96B49,P21796,Q15388,O95140 | Processes and pathways | Reactome Pathways | msigdb_reactome | 35,72,264,16,346,429 | 2069,429,1077,2144,16,1970,433,346,72,264,2234,35 | -0.33023269302803204,0.7193596211985692,0.1465756160978675,-0.3599276825042347,3.844530607020698,-0.2714249570573372,0.7193596211985692,0.8797499948322487,2.683879218936928,1.120344057573255,-0.38981994606341763,3.255890605195437 | 3,120 |
Glycerophospholipid metabolic process | 14 | 54 | 2.502052 | 0.012348 | Q5H8A4,Q9NPH0,Q96S52,P35790,Q8NCC3,Q9BVG9,Q9NZC3,Q969N2,Q10713,Q96N66,Q8TBX8,O00459,Q9NX62,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 248,6,302,42,11,144,283,385,55,153,219,339,224,30 | 2457,2755,339,2548,703,2502,1589,764,2782,1183,2074,1594,2203,42,1087,381,2934,2998,949,999,55,248,553,506,665,1550,638,1062,2170,11,537,219,30,1560,1010,640,385,153,1163,302,454,2489,1999,144,788,1213,6,1817,2776,224,3005,283,978,853 | -0.5734566251984043,-0.8636557041179473,0.8797499948322487,-0.6363634842619023,0.4048447144069418,-0.6048009638951245,-0.09949469747666943,0.3543879449769868,-0.8970706209351134,0.09305929398318494,-0.33023269302803204,-0.09949469747666943,-0.38981994606341763,3.139985047591634,0.1465756160978675,0.8117366781974475,-1.... | 3,120 |
Lysosome | 13 | 46 | 2.499158 | 0.012449 | O14773,P11117,P20645,Q13510,P10619,Q14108,Q8NCC3,P17900,P15586,O15118,P50897,O75503,Q93050 | Processes and pathways | KEGG Pathways | msigdb_kegg | 66,97,165,71,200,105,11,268,238,112,48,115,279 | 1497,2385,66,112,675,892,115,1902,1124,898,2070,2618,591,1334,2836,1593,200,97,2996,1451,3088,238,476,268,165,3016,48,1715,276,2433,3074,1405,1408,71,105,744,11,2173,279,542,426,1572,2829,2543,1440,362 | -0.07147184402573621,-0.5114114008305259,2.7850237629841788,2.1200791235371135,0.429857390182749,0.25170495959874245,2.086376421063753,-0.24230752653304063,0.11989823952072967,0.25170495959874245,-0.33023269302803204,-0.7001544799726708,0.5040506253802524,0.011554613903006978,-0.9646412623937256,-0.09949469747666943,1.... | 3,120 |
Clumsiness | 8 | 22 | 2.486893 | 0.012886 | Q9NZJ7,O14773,Q13510,Q15067,O43819,Q9NR77,O75503,P35670 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 426,66,71,300,295,80,115,255 | 1225,66,1034,675,295,115,985,2808,2623,255,803,1244,433,71,300,1151,1355,1931,1365,80,426,2966 | 0.06605695177290508,2.7850237629841788,0.1730932216945844,0.429857390182749,1.012646583383761,2.086376421063753,0.19945282519176055,-0.9307313466100875,-0.7001544799726708,1.1415631395121968,0.32894076142978074,0.06605695177290508,0.7193596211985692,2.683879218936928,1.012646583383761,0.11989823952072967,0.011554613903... | 3,120 |
Proximal muscle weakness | 17 | 63 | 2.482584 | 0.013043 | P35670,P50402,Q13126,Q8TD16,Q13510,Q8NI60,P00846,P50336,Q9BQT8,P21912,P51530,Q99720,P07196,O95140,Q13501,O60313,P36551 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 255,290,133,326,71,228,9,170,101,477,297,20,119,429,433,340,127 | 1378,340,617,429,1588,9,1766,2956,985,119,1450,1272,1593,2985,1079,3088,1235,1646,477,2022,550,2808,1239,255,127,170,290,1840,804,297,1342,502,2764,2591,1194,133,2399,433,71,2162,2876,1200,2401,1793,1474,2403,687,1931,2225,228,2567,326,668,1064,1365,20,1427,101,1313,2113,849,1631,652 | -0.015949191785796384,0.8797499948322487,0.4794588708276966,0.7193596211985692,-0.09949469747666943,4.375070750907427,-0.18463413695639644,-1.2453206396228493,0.19945282519176055,2.0181394542083764,-0.043624015597528217,0.03888935479482263,-0.09949469747666943,-1.3551362796599622,0.1465756160978675,-2.2504606922272252,... | 3,120 |
Pink1 prkn mediated mitophagy | 6 | 9 | 2.482353 | 0.013052 | Q9NS69,Q8N4H5,Q96B49,P21796,Q15388,O95140 | Processes and pathways | Reactome Pathways | msigdb_reactome | 35,72,264,16,346,429 | 2069,429,1077,16,433,346,72,264,35 | -0.33023269302803204,0.7193596211985692,0.1465756160978675,3.844530607020698,0.7193596211985692,0.8797499948322487,2.683879218936928,1.120344057573255,3.255890605195437 | 3,120 |
Secondary alcohol metabolic process | 14 | 40 | 2.468892 | 0.013553 | Q14739,Q16850,P49748,P37268,P16435,Q15392,P04035,O15118,Q14534,P48449,Q8WTV0,P48735,P35610,O75845 | Processes and pathways | GO Biological process | msigdb_gobp | 195,65,344,68,327,230,267,112,172,85,30,275,122,310 | 112,2342,588,310,1179,1899,2616,267,1902,1510,402,327,2931,122,68,2391,85,275,344,2715,1843,1967,777,3074,1529,1664,600,2766,172,195,2269,1541,230,1982,686,65,30,2990,699,1173 | 2.1200791235371135,-0.4807050971530273,0.5040506253802524,0.9688011263013478,0.09305929398318494,-0.24230752653304063,-0.7001544799726708,1.0990194895203063,-0.24230752653304063,-0.07147184402573621,0.7657939331769242,0.9245051560552161,-1.1735319573878251,2.0009038654063014,2.770727945453716,-0.5114114008305259,2.4891... | 3,120 |
Apical plasma membrane | 8 | 48 | 2.435419 | 0.014875 | P53985,P41440,Q8TAD4,Q99808,P08183,Q9Y4G8,P30825,P36551 | Localization | GO Cellular component | msigdb_gocc | 104,204,208,242,22,125,126,127 | 1225,2576,940,2063,893,1271,1829,799,862,1332,22,767,1043,1769,2255,1392,1275,2712,447,1081,1706,1774,126,904,262,127,1460,204,1842,104,2318,626,2433,1469,1974,2360,2672,781,576,1095,208,1426,242,1683,1217,544,125,1175 | 0.06605695177290508,-0.6681470252093221,0.22565616698772623,-0.33023269302803204,0.25170495959874245,0.03888935479482263,-0.21337800008247138,0.32894076142978074,0.2776008882438347,0.011554613903006978,3.744867759885806,0.3543879449769868,0.1730932216945844,-0.18463413695639644,-0.4199119328370344,-0.015949191785796384... | 3,120 |
Action tremor | 9 | 55 | 2.432362 | 0.015001 | Q5JRX3,O14773,P00846,Q8NC56,Q14108,P07814,Q9H6K4,Q9NR77,Q99720 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 160,66,9,138,105,14,111,80,20 | 2834,66,1034,2063,675,460,1178,1038,1271,429,1588,9,3014,2852,2139,14,2554,1187,1080,1963,2078,1776,1239,204,1596,1521,502,1844,1781,1531,105,1003,160,1151,2939,2165,638,1062,138,3092,3066,1104,20,1750,111,2493,1021,80,410,426,1172,1437,649,415,564 | -0.9646412623937256,2.7850237629841788,0.1730932216945844,-0.33023269302803204,0.429857390182749,0.6724238788270614,0.09305929398318494,0.1730932216945844,0.03888935479482263,0.7193596211985692,-0.09949469747666943,4.375070750907427,-1.5057183812598571,-0.9988038179626447,-0.3599276825042347,3.9095867503469988,-0.63636... | 3,120 |
Steroid biosynthetic process | 11 | 44 | 2.430623 | 0.015073 | Q14739,Q16850,P37268,Q13510,Q15392,Q53GQ0,P04035,Q14534,P48449,P30536,O75845 | Processes and pathways | GO Biological process | msigdb_gobp | 195,65,68,71,230,205,267,172,85,25,310 | 588,310,1899,2616,267,862,1510,402,2620,327,1905,1963,2931,1282,25,68,2391,85,1843,1967,777,1664,600,71,2766,172,195,1541,230,1730,1148,1982,686,65,205,2107,1622,723,2111,887,1567,699,2337,3061 | 0.5040506253802524,0.9688011263013478,-0.24230752653304063,-0.7001544799726708,1.0990194895203063,0.2776008882438347,-0.07147184402573621,0.7657939331769242,-0.7001544799726708,0.9245051560552161,-0.24230752653304063,-0.2714249570573372,-1.1735319573878251,0.03888935479482263,3.607914396820148,2.770727945453716,-0.5114... | 3,120 |
Metalloendopeptidase activity | 8 | 15 | 2.418579 | 0.015581 | O43847,Q5JRX3,Q9BYT8,Q9Y4W6,P42892,O75844,Q10713,P22695 | Functions | GO Molecular function | msigdb_gomf | 220,160,425,564,102,13,55,274 | 220,2458,13,1274,274,102,1655,55,160,1743,2858,609,1426,425,564 | 1.2461096037129336,-0.5734566251984043,3.9629821531008274,0.03888935479482263,1.0775884567819758,2.26843717639146,-0.12769463103528156,2.9114638007546514,1.5835213327153648,-0.1560737352527625,-0.9988038179626447,0.5040506253802524,-0.015949191785796384,0.7426388328088186,0.5528233698913807 | 3,120 |
Vacuolar lumen | 18 | 64 | 2.39235 | 0.016741 | Q99536,Q9NZJ7,O14773,P11117,Q9UM22,Q9H7Z7,Q13510,P10619,Q14108,Q8IV08,P16278,P17900,P15586,P50897,P54802,Q8NHP8,Q13217,P38435 | Localization | GO Cellular component | msigdb_gocc | 493,426,66,97,37,135,71,200,105,232,476,268,238,48,276,90,314,500 | 1227,2340,66,675,2616,678,1902,1124,898,2070,1389,827,2618,1230,591,1593,200,97,1644,1832,3088,238,476,268,499,1910,2203,500,3016,2084,1522,48,2151,1843,1715,1716,276,2764,1242,3074,1971,1915,2475,1665,314,71,105,1200,232,2856,90,1562,968,1810,493,610,1257,1875,135,1069,426,37,2543,2731 | 0.06605695177290508,-0.4807050971530273,2.7850237629841788,0.429857390182749,-0.7001544799726708,0.429857390182749,-0.24230752653304063,0.11989823952072967,0.25170495959874245,-0.33023269302803204,-0.015949191785796384,0.30334561141450944,-0.7001544799726708,0.06605695177290508,0.5040506253802524,-0.09949469747666943,1... | 3,120 |
Cholesterol biosynthesis pathway | 6 | 14 | 2.370863 | 0.017747 | Q16850,P37268,P04035,Q14534,P48449,O75845 | Processes and pathways | WikiPathways | msigdb_wp | 65,68,267,172,85,310 | 310,267,402,68,85,1967,1664,2766,172,1541,1982,686,65,699 | 0.9688011263013478,1.0990194895203063,0.7657939331769242,2.770727945453716,2.489102096014749,-0.2714249570573372,-0.12769463103528156,-0.8636557041179473,1.487036333627781,-0.07147184402573621,-0.2714249570573372,0.429857390182749,2.8134649963657146,0.429857390182749 | 3,120 |
Glycoprotein biosynthetic process | 10 | 51 | 2.368918 | 0.01784 | Q96JB2,Q99805,O60476,O43505,Q96L58,O15118,Q7LGA3,Q8NCH0,Q9H6U8,P35610 | Processes and pathways | GO Biological process | msigdb_gobp | 96,131,192,141,175,112,17,117,188,122 | 2709,112,2249,141,192,443,858,1639,2502,617,2581,765,1643,3089,2080,122,988,1649,2089,2397,2093,1469,1194,2526,717,214,838,1246,1144,1004,720,17,2701,666,117,1100,370,96,175,1164,131,319,1366,1066,2117,694,188,849,1882,1261,2572 | -0.7975501035896743,2.1200791235371135,-0.4199119328370344,1.8424923729445961,1.388303199401113,0.6959550565518066,0.2776008882438347,-0.12769463103528156,-0.6048009638951245,0.4794588708276966,-0.6681470252093221,0.3543879449769868,-0.12769463103528156,-2.2504606922272252,-0.33023269302803204,2.0009038654063014,0.1994... | 3,120 |
Peptide binding | 15 | 64 | 2.361358 | 0.018208 | P24390,O14773,Q9BYT8,Q9UIQ6,O00264,Q9H7Z7,Q9NZ08,P42892,Q15392,P10321,P55786,Q15388,O00629,Q8WTV0,O15212 | Functions | GO Molecular function | msigdb_gomf | 33,66,425,132,191,135,100,102,230,333,54,346,155,30,363 | 191,1697,2297,155,66,363,2710,2069,1901,861,1769,1334,2836,333,1274,2738,2464,33,2944,1964,3090,2840,903,1396,2026,1461,102,3009,1596,1400,1520,1049,2785,1780,54,1659,2588,599,2716,1723,1666,1198,2562,2163,346,230,1156,1157,30,966,1481,969,1998,2333,425,1017,135,2053,2055,100,1174,440,132,2867 | 1.388303199401113,-0.1560737352527625,-0.45020613666046194,1.621506944075928,2.7850237629841788,0.8345267182780652,-0.7975501035896743,-0.33023269302803204,-0.24230752653304063,0.2776008882438347,-0.18463413695639644,0.011554613903006978,-0.9646412623937256,0.9021855262027676,0.03888935479482263,-0.8304832815585822,-0.... | 3,120 |
Intrinsic component of endoplasmic reticulum membrane | 20 | 53 | 2.353946 | 0.018575 | O75844,Q9NPA0,Q96S52,Q9UM00,Q8TCT9,P10321,Q9NQC3,O75298,Q96A33,Q9Y282,Q86XL3,Q5H8A4,P51572,Q8TB61,O95470,Q8N4V1,O76024,Q15629,Q969N2,Q12981 | Localization | GO Cellular component | msigdb_gocc | 13,409,302,441,325,333,212,81,463,87,95,248,354,369,107,368,254,121,385,382 | 822,3022,2994,81,13,254,107,1901,861,333,2944,2024,2512,354,1402,2588,382,2637,920,1296,121,2563,248,921,664,2404,95,666,368,1556,369,325,640,385,1422,463,302,1425,1626,1165,1315,2707,409,212,2913,511,2570,2928,699,441,87,729,1224 | 0.30334561141450944,-1.5441372114598413,-1.3923270876756626,2.5801554718278767,3.9629821531008274,1.1415631395121968,2.1535101765609372,-0.24230752653304063,0.2776008882438347,0.9021855262027676,-1.2092868657343552,-0.3007325721587227,-0.6048009638951245,0.8571974386256007,-0.015949191785796384,-0.6681470252093221,0.81... | 3,120 |
Steroid biosynthesis | 6 | 11 | 2.348673 | 0.01884 | Q16850,P37268,Q15392,Q14534,P48449,P35610 | Processes and pathways | KEGG Pathways | msigdb_kegg | 65,68,230,172,85,122 | 310,122,68,3016,85,172,230,1982,686,65,699 | 0.9688011263013478,2.0009038654063014,2.770727945453716,-1.5057183812598571,2.489102096014749,1.487036333627781,1.2045970593385245,-0.2714249570573372,0.429857390182749,2.8134649963657146,0.429857390182749 | 3,120 |
Visual loss | 6 | 51 | 2.343903 | 0.019083 | O14773,P00846,P07814,P50897,P48449,Q10713 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 66,9,14,48,85,55 | 1891,1578,2248,730,66,1698,340,1178,2458,115,1446,429,225,2251,9,1901,3014,2956,861,14,1831,2462,770,2080,1397,1087,85,48,1401,1523,2392,502,1717,1531,55,2398,2357,2267,2790,1735,638,2173,1063,1064,2279,579,524,2111,2493,1220,426 | -0.24230752653304063,-0.09949469747666943,-0.4199119328370344,0.37968874363881105,2.7850237629841788,-0.1560737352527625,0.8797499948322487,0.09305929398318494,-0.5734566251984043,2.086376421063753,-0.043624015597528217,0.7193596211985692,1.2254037240919913,-0.4199119328370344,4.375070750907427,-0.24230752653304063,-1.... | 3,120 |
Limb ataxia | 7 | 27 | 2.340601 | 0.019253 | O14773,Q14108,P41440,Q9NR77,O75298,P07196,Q10713 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 66,105,204,80,81,119,55 | 2834,66,2063,81,1902,2852,119,2617,3002,1278,2808,1776,204,502,55,433,105,232,1931,1104,2113,1751,80,410,1172,1437,564 | -0.9646412623937256,2.7850237629841788,-0.33023269302803204,2.5801554718278767,-0.24230752653304063,-0.9988038179626447,2.0181394542083764,-0.7001544799726708,-1.429818003064028,0.03888935479482263,-0.9307313466100875,-0.18463413695639644,1.3279431624639007,0.6249765506068089,2.9114638007546514,0.7193596211985692,2.186... | 3,120 |
Parkinsons disease | 14 | 57 | 2.337557 | 0.01941 | P24539,P00403,Q9UDW1,P45880,O14548,P00846,P14406,Q9Y277,P21796,O96000,O14949,P14927,P22695,P13073 | Processes and pathways | KEGG Pathways | msigdb_kegg | 129,225,36,70,199,9,41,78,16,178,19,147,274,57 | 3021,2062,199,19,1955,3104,2780,2930,1178,2551,1385,568,529,444,1587,2503,178,225,9,3014,1229,766,1507,864,2711,1079,1335,57,41,147,1771,2584,288,16,477,2022,274,129,1773,2147,2808,2309,711,70,2814,2032,3040,3029,3017,911,1723,745,958,3066,36,78,565 | -1.5441372114598413,-0.33023269302803204,1.3481584340693418,3.80054934068688,-0.2714249570573372,-2.9227381542310105,-0.8970706209351134,-1.1735319573878251,0.09305929398318494,-0.6363634842619023,-0.015949191785796384,0.5285049852239486,0.5770071775774535,0.6959550565518066,-0.09949469747666943,-0.6048009638951245,1.4... | 3,120 |
Organic hydroxy compound biosynthetic process | 14 | 52 | 2.336124 | 0.019485 | Q14739,Q16850,P37268,Q13510,P16435,P00374,P05091,Q15392,P04035,Q14534,P48449,Q9Y4G8,P14324,O75845 | Processes and pathways | GO Biological process | msigdb_gobp | 195,65,68,71,327,44,76,230,267,172,85,125,402,310 | 2457,1760,1378,587,2129,588,310,1899,44,2616,267,1902,76,863,1510,402,327,1904,1905,1963,1282,419,68,2391,85,1843,1967,777,2036,1664,1469,600,71,2766,172,195,1541,230,1982,686,2271,65,1622,1482,723,3066,2111,543,699,3061,125,2983 | -0.5734566251984043,-0.18463413695639644,-0.015949191785796384,0.5040506253802524,-0.3599276825042347,0.5040506253802524,0.9688011263013478,-0.24230752653304063,3.087373369880343,-0.7001544799726708,1.0990194895203063,-0.24230752653304063,2.6397490931199465,0.2776008882438347,-0.07147184402573621,0.7657939331769242,0.9... | 3,120 |
Lipase activity | 7 | 19 | 2.326645 | 0.019984 | Q8N2A8,Q8NCG7,Q8NCC3,Q8IV08,Q9NZC3,Q8NHP8,Q9H6V9 | Functions | GO Molecular function | msigdb_gomf | 137,301,11,232,283,90,59 | 2014,2302,296,1594,2203,2512,3016,232,638,137,1062,2170,11,301,90,59,3005,283,1952 | -0.3007325721587227,-0.45020613666046194,1.012646583383761,-0.09949469747666943,-0.38981994606341763,-0.6048009638951245,-1.5057183812598571,1.2045970593385245,0.4794588708276966,1.8782176443063971,0.1730932216945844,-0.3599276825042347,4.159435423734304,1.012646583383761,2.427254953547532,2.8837057870744482,-1.4298180... | 3,120 |
Sphingolipid metabolic process | 11 | 27 | 2.324316 | 0.020109 | Q9NZJ7,Q06136,Q99805,Q53H12,Q13510,Q8NCC3,P16278,O95470,P17900,P50897,Q9NZD2 | Processes and pathways | GO Biological process | msigdb_gobp | 426,130,131,450,71,11,476,107,268,48,252 | 2885,587,2129,1955,107,1902,898,2070,2618,476,268,1905,1514,48,1665,130,71,450,664,11,131,3005,2913,252,426,511,2241 | -1.0679010003564908,0.5040506253802524,-0.3599276825042347,-0.2714249570573372,2.1535101765609372,-0.24230752653304063,0.25170495959874245,-0.33023269302803204,-0.7001544799726708,0.6487648093812882,1.0990194895203063,-0.24230752653304063,-0.07147184402573621,2.993609575094583,-0.12769463103528156,1.9312396535039034,2.... | 3,120 |
Protease | 22 | 80 | 2.321975 | 0.020234 | Q7Z2K6,P28074,Q9UIQ6,P42785,O75844,Q9HB40,Q5JRX3,Q9BYT8,Q4J6C6,P28072,Q9H3G5,P55786,O14773,Q8TCT9,P10619,Q16740,P09960,Q99436,O43847,Q9NZ08,P42892,Q96K76 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 257,378,132,7,13,32,160,425,39,418,43,54,66,325,200,201,213,465,220,100,102,371 | 1442,1116,66,1955,220,2458,13,1122,860,945,2617,213,200,2803,1274,2074,418,378,2585,2622,1458,7,102,1913,907,1653,1779,1655,1780,1715,2262,54,1135,2746,2440,2697,2594,201,39,160,2529,3057,257,1863,1551,325,878,640,1743,1563,1994,3080,2858,2679,2598,371,1162,492,609,465,3066,1426,425,646,43,2898,2239,1106,32,1021,1940,2... | -0.043624015597528217,0.11989823952072967,2.7850237629841788,-0.2714249570573372,1.2461096037129336,-0.5734566251984043,3.9629821531008274,0.11989823952072967,0.2776008882438347,0.22565616698772623,-0.7001544799726708,1.287222609209894,1.3481584340693418,-0.9307313466100875,0.03888935479482263,-0.33023269302803204,0.74... | 3,120 |
Abnormal visual electrophysiology | 16 | 52 | 2.31295 | 0.020725 | Q9NZJ7,O14773,Q53H12,Q9H936,P00846,Q15067,Q86YH6,Q15555,Q9GZY8,P50897,O43924,Q9H0F7,O75503,O95140,P54098,O60313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 426,66,450,496,9,300,328,393,207,48,79,352,115,429,502,340 | 66,1698,2298,1036,675,2342,79,3070,340,115,1581,2800,429,9,1079,499,1397,1189,1087,2715,48,1401,502,2519,1717,573,1975,1246,1981,300,393,782,450,1615,2368,328,638,1556,1063,964,1362,815,2000,207,352,1167,496,1217,2980,2240,426,2607 | 2.7850237629841788,-0.1560737352527625,-0.45020613666046194,0.1730932216945844,0.429857390182749,-0.4807050971530273,2.610061135094578,-1.9889367176870343,0.8797499948322487,2.086376421063753,-0.09949469747666943,-0.9307313466100875,0.7193596211985692,4.375070750907427,0.1465756160978675,0.6249765506068089,-0.015949191... | 3,120 |
Alcohol biosynthetic process | 15 | 37 | 2.309753 | 0.020902 | Q14739,Q16850,P37268,Q13510,P35270,P16435,P00374,Q15392,P04035,Q9NPH2,Q12770,P48449,O15269,P14324,O75845 | Processes and pathways | GO Biological process | msigdb_gobp | 195,65,68,71,419,327,44,230,267,543,600,85,587,402,310 | 2457,587,2129,588,310,1899,44,2616,267,1902,863,1510,402,327,1904,419,68,2391,85,1843,1967,777,2036,1664,600,71,2766,195,1541,230,1982,686,2271,65,3066,543,699 | -0.5734566251984043,0.5040506253802524,-0.3599276825042347,0.5040506253802524,0.9688011263013478,-0.24230752653304063,3.087373369880343,-0.7001544799726708,1.0990194895203063,-0.24230752653304063,0.2776008882438347,-0.07147184402573621,0.7657939331769242,0.9245051560552161,-0.24230752653304063,0.7426388328088186,2.7707... | 3,120 |
Ferroptosis | 6 | 24 | 2.305743 | 0.021125 | P37268,P45880,Q9Y277,P09601,P04035,Q9NZ45 | Processes and pathways | WikiPathways | msigdb_wp | 68,70,78,296,267,86 | 1893,1589,825,678,267,2685,2505,767,296,327,1131,68,70,1464,1596,2672,2819,2638,1415,1796,1683,86,934,78 | -0.24230752653304063,-0.09949469747666943,0.30334561141450944,0.429857390182749,1.0990194895203063,-0.764852983812969,-0.6048009638951245,0.3543879449769868,1.012646583383761,0.9245051560552161,0.11989823952072967,2.770727945453716,2.683879218936928,-0.043624015597528217,-0.09949469747666943,-0.7323887974882097,-0.9307... | 3,120 |
Amino acid transport | 11 | 20 | 2.3048 | 0.021178 | Q9H936,Q9H9B4,Q8TDW0,P55011,O75746,O75915,P08195,Q9UJS0,P21359,P30825,Q6P4A7 | Processes and pathways | GO Biological process | msigdb_gobp | 496,526,423,626,567,621,767,411,770,126,719 | 940,1378,1640,567,621,1768,767,770,126,626,1296,1981,1415,719,423,882,1683,496,526,411 | 0.22565616698772623,-0.015949191785796384,-0.12769463103528156,0.5285049852239486,0.4794588708276966,-0.18463413695639644,0.3543879449769868,0.3543879449769868,1.9662172504490403,0.4794588708276966,0.03888935479482263,-0.2714249570573372,-0.015949191785796384,0.4048447144069418,0.7426388328088186,0.2776008882438347,-0.... | 3,120 |
golgi | 11 | 66 | 2.303063 | 0.021275 | Q9Y487,P36543,Q9BXB4,Q9UI14,Q8IXU6,Q8TAD4,O15127,P53367,Q15907,Q5VW38,Q8NBN3 | Localization | OpenCell Localization | opencell_localization | 362,262,303,139,49,208,118,245,61,62,31 | 1499,702,2548,940,2128,1117,118,1035,943,1271,2459,1588,1334,2836,2256,1046,1905,2259,262,2714,625,245,1524,1466,1657,2691,1291,1660,714,2091,1405,999,2526,1853,1146,956,2361,744,61,62,2821,49,1554,923,31,208,2406,927,1479,523,303,373,1167,1876,756,1817,2241,544,727,139,441,1031,938,1222,362,1577 | -0.07147184402573621,0.4048447144069418,-0.6363634842619023,0.22565616698772623,-0.3599276825042347,0.11989823952072967,2.035303964448664,0.1730932216945844,0.22565616698772623,0.03888935479482263,-0.5734566251984043,-0.09949469747666943,0.011554613903006978,-0.9646412623937256,-0.4199119328370344,0.1730932216945844,-0... | 3,120 |
Oxidase | 9 | 21 | 2.299677 | 0.021467 | O15260,P20674,O43169,O14548,P14406,Q15067,O43819,O75845,P36551 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 321,288,38,199,41,300,295,310,127 | 199,762,321,38,295,310,1583,2711,2985,2837,41,1771,288,2933,127,344,300,686,1733,2532,1168 | 1.3481584340693418,0.3543879449769868,0.9467099920148521,3.1919142087444814,1.012646583383761,0.9688011263013478,-0.09949469747666943,-0.7975501035896743,-1.3551362796599622,-0.9646412623937256,3.139985047591634,-0.18463413695639644,1.0344030160862734,-1.1735319573878251,1.9662172504490403,0.8797499948322487,1.01264658... | 3,120 |
Dicarboxylic acid transmembrane transporter activity | 6 | 8 | 2.299641 | 0.021469 | Q9H936,Q9BQT8,P41440,Q9UJS0,Q02978,Q9UBX3 | Functions | GO Molecular function | msigdb_gomf | 496,101,204,411,432,157 | 567,204,432,1415,101,496,157,411 | 0.5285049852239486,1.3279431624639007,0.7193596211985692,-0.015949191785796384,2.2845974095289043,0.6487648093812882,1.621506944075928,0.7657939331769242 | 3,120 |
Glycerophospholipid biosynthetic process | 11 | 38 | 2.296717 | 0.021635 | Q5H8A4,Q9NPH0,Q96S52,P35790,Q9BVG9,Q969N2,Q10713,Q96N66,Q8TBX8,O00459,Q9NX62 | Processes and pathways | GO Biological process | msigdb_gobp | 248,6,302,42,144,385,55,153,219,339,224 | 2755,339,2548,703,2502,1589,764,2782,1183,2074,42,381,2998,999,55,248,553,506,665,1550,537,219,1560,1010,640,385,153,1163,302,2489,1999,144,788,6,1817,2776,224,978 | -0.8636557041179473,0.8797499948322487,-0.6363634842619023,0.4048447144069418,-0.6048009638951245,-0.09949469747666943,0.3543879449769868,-0.8970706209351134,0.09305929398318494,-0.33023269302803204,3.139985047591634,0.8117366781974475,-1.3923270876756626,0.19945282519176055,2.9114638007546514,1.1626777008156755,0.5528... | 3,120 |
Electron transport chain oxphos system in mitochondria | 14 | 54 | 2.296535 | 0.021645 | P24539,P00403,Q7KZN9,Q9UDW1,Q9Y6N1,O14548,P00846,P14406,O96000,O14949,P14927,O75964,P22695,P13073 | Processes and pathways | WikiPathways | msigdb_wp | 129,225,185,36,198,199,9,41,178,19,147,52,274,57 | 3021,2062,199,19,3104,2780,2930,1178,2551,1385,1583,568,52,529,444,1587,2503,178,225,9,3014,1229,766,864,2711,1079,1335,57,41,147,1771,2584,288,477,274,129,1773,2147,2808,2309,711,2814,2032,3040,3029,2632,1845,745,958,185,36,936,565,198 | -1.5441372114598413,-0.33023269302803204,1.3481584340693418,3.80054934068688,-2.9227381542310105,-0.8970706209351134,-1.1735319573878251,0.09305929398318494,-0.6363634842619023,-0.015949191785796384,-0.09949469747666943,0.5285049852239486,2.925271544766199,0.5770071775774535,0.6959550565518066,-0.09949469747666943,-0.6... | 3,120 |
Biological oxidations | 11 | 43 | 2.290781 | 0.021976 | Q16850,O43169,P07099,P16435,Q86WA6,P05091,Q8TB61,Q9NUJ1,P21964,P30837,Q9NX62 | Processes and pathways | Reactome Pathways | msigdb_reactome | 65,38,10,327,173,76,369,282,146,60,224 | 2248,548,38,2299,2869,2578,1639,2661,2782,2616,76,10,1769,3008,1903,1392,327,2738,146,2931,2932,1964,60,802,1464,1596,1663,2322,65,1350,1058,173,369,1307,1995,1162,372,1998,1683,282,224,2290,728 | -0.4199119328370344,0.5528233698913807,3.1919142087444814,-0.45020613666046194,-1.033222533253154,-0.6681470252093221,-0.12769463103528156,-0.7323887974882097,-0.8970706209351134,-0.7001544799726708,2.6397490931199465,4.209515969875745,-0.18463413695639644,-1.4676135569727793,-0.24230752653304063,-0.015949191785796384,... | 3,120 |
Regulation of hormone levels | 13 | 60 | 2.2714 | 0.023123 | Q9HB40,P42892,Q16836,P53985,P16435,O95470,O75844,Q53GQ0,Q8TAD4,Q8N5M9,P30536,P50416,Q15907 | Processes and pathways | GO Biological process | msigdb_gobp | 32,102,347,104,327,107,13,205,208,338,25,403,61 | 2902,2576,1265,1893,2012,1271,13,107,569,1590,799,862,1043,1274,2620,327,1186,1905,25,2841,1087,102,2626,403,1401,1048,104,2520,2091,912,2525,2718,1409,659,2160,2672,1148,61,2271,347,205,534,1301,338,1992,2107,436,208,1063,2648,2680,751,3066,2111,32,1020,699,1437,980,1757 | -1.1028428854778956,-0.6681470252093221,0.03888935479482263,-0.24230752653304063,-0.3007325721587227,0.03888935479482263,3.9629821531008274,2.1535101765609372,0.5285049852239486,-0.09949469747666943,0.32894076142978074,0.2776008882438347,0.1730932216945844,0.03888935479482263,-0.7001544799726708,0.9245051560552161,0.09... | 3,120 |
Sensorimotor neuropathy | 9 | 30 | 2.269471 | 0.02324 | P00403,Q9Y2R0,P00846,P41440,Q9NR77,P07196,Q13217,O60313,O95831 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 225,2,9,204,80,119,314,340,401 | 730,2129,340,401,225,9,3014,862,119,1278,2932,1776,1087,204,1521,1401,502,2764,2631,2398,314,1002,2938,1062,1064,80,2185,426,2,564 | 0.37968874363881105,-0.3599276825042347,0.8797499948322487,0.7657939331769242,1.2254037240919913,4.375070750907427,-1.5057183812598571,0.2776008882438347,2.0181394542083764,0.03888935479482263,-1.1735319573878251,-0.18463413695639644,0.1465756160978675,1.3279431624639007,-0.07147184402573621,-0.015949191785796384,0.624... | 3,120 |
Membrane lipid biosynthetic process | 12 | 22 | 2.246799 | 0.024653 | Q06136,Q99805,Q53H12,Q8NBX0,Q5H8A4,Q13510,Q96S52,Q92643,O95470,O15269,Q9P035,Q969N2 | Processes and pathways | GO Biological process | msigdb_gobp | 130,131,450,5,248,71,302,640,107,587,511,385 | 2885,587,2129,2502,107,1902,1905,1665,130,838,71,450,248,664,5,640,385,302,131,3005,511,2241 | -1.0679010003564908,0.5040506253802524,-0.3599276825042347,-0.6048009638951245,2.1535101765609372,-0.24230752653304063,-0.24230752653304063,-0.12769463103528156,1.9312396535039034,0.30334561141450944,2.683879218936928,0.6959550565518066,1.1626777008156755,0.45472828026538425,4.641924981314761,0.4794588708276966,0.81173... | 3,120 |
Sterol metabolic process | 13 | 37 | 2.245754 | 0.02472 | Q14739,Q16850,P49748,P37268,P16435,Q15392,P04035,O15118,Q14534,P48449,Q8WTV0,P35610,O75845 | Processes and pathways | GO Biological process | msigdb_gobp | 195,65,344,68,327,230,267,112,172,85,30,122,310 | 112,588,310,1899,2616,267,1902,1510,402,327,2931,122,68,3016,2391,85,344,1843,1967,777,3074,1529,1664,600,2766,172,195,2269,1541,230,1982,686,65,30,699,1173,3061 | 2.1200791235371135,0.5040506253802524,0.9688011263013478,-0.24230752653304063,-0.7001544799726708,1.0990194895203063,-0.24230752653304063,-0.07147184402573621,0.7657939331769242,0.9245051560552161,-1.1735319573878251,2.0009038654063014,2.770727945453716,-1.5057183812598571,-0.5114114008305259,2.489102096014749,0.879749... | 3,120 |
Liposaccharide metabolic process | 7 | 17 | 2.245729 | 0.024721 | Q99805,Q8NBX0,Q96S52,P17900,Q9NZD2,Q5H8A4,Q969N2 | Processes and pathways | GO Biological process | msigdb_gobp | 131,5,302,268,252,248,385 | 2502,1902,1124,898,2070,2618,476,268,1665,838,248,5,640,385,302,131,252 | -0.6048009638951245,-0.24230752653304063,0.11989823952072967,0.25170495959874245,-0.33023269302803204,-0.7001544799726708,0.6487648093812882,1.0990194895203063,-0.12769463103528156,0.30334561141450944,1.1626777008156755,4.641924981314761,0.4794588708276966,0.8117366781974475,1.012646583383761,1.9312396535039034,1.16267... | 3,120 |
Organic hydroxy compound transport | 7 | 30 | 2.239123 | 0.025148 | O95486,P53985,O15118,P30536,Q14728,P35610,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 217,104,112,25,58,122,30 | 1636,112,1268,217,1389,987,1905,1963,1282,25,122,104,3074,912,2718,58,2217,1552,2924,30,1622,723,3066,303,1213,1170,2241,3012,1173,2057 | -0.12769463103528156,2.1200791235371135,0.03888935479482263,1.2667156015614143,-0.015949191785796384,0.19945282519176055,-0.24230752653304063,-0.2714249570573372,0.03888935479482263,3.607914396820148,2.0009038654063014,2.186673620608435,-1.9889367176870343,0.25170495959874245,-0.7975501035896743,2.8837057870744482,-0.3... | 3,120 |
Oxidative phosphorylation | 16 | 62 | 2.236678 | 0.025307 | P24539,P00403,Q7KZN9,Q9UDW1,P36543,Q9Y6N1,O14548,P00846,P14406,O96000,O14949,Q93050,P14927,O75964,P22695,P13073 | Processes and pathways | KEGG Pathways | msigdb_kegg | 129,225,185,36,262,198,199,9,41,178,19,279,147,52,274,57 | 3021,2062,199,19,3104,2780,2930,1178,2551,1385,568,52,529,444,1587,2503,178,225,9,3014,766,1507,864,2711,57,41,147,1771,2584,288,1081,769,477,274,129,1773,2147,2808,2309,711,262,1460,2814,2032,3040,3029,2632,1845,2433,2978,744,745,958,185,2961,279,2911,36,1572,362,565,198 | -1.5441372114598413,-0.33023269302803204,1.3481584340693418,3.80054934068688,-2.9227381542310105,-0.8970706209351134,-1.1735319573878251,0.09305929398318494,-0.6363634842619023,-0.015949191785796384,0.5285049852239486,2.925271544766199,0.5770071775774535,0.6959550565518066,-0.09949469747666943,-0.6048009638951245,1.467... | 3,120 |
Retinal degeneration | 13 | 54 | 2.234731 | 0.025435 | O14773,Q13510,P51648,Q7LGA3,P50897,Q9H0F7,Q96F07,Q9NW15,O75503,Q10713,Q96PZ0,O60313,O75648 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 66,71,47,17,48,352,464,410,115,55,491,340,498 | 2498,66,2298,340,2426,115,1581,498,824,3023,1766,1902,861,2801,1646,2554,499,1707,2078,2080,1460,803,1966,2715,48,47,2630,626,833,1971,1405,1532,55,71,1001,1615,17,1303,638,877,1099,1063,964,1362,464,491,2111,1751,352,849,2980,410,978,1437 | -0.6048009638951245,2.7850237629841788,-0.45020613666046194,0.8797499948322487,-0.5423276822514903,2.086376421063753,-0.09949469747666943,0.6249765506068089,0.30334561141450944,-1.5441372114598413,-0.18463413695639644,-0.24230752653304063,0.2776008882438347,-0.9307313466100875,-0.12769463103528156,-0.6363634842619023,0... | 3,120 |
Aganglionic megacolon | 8 | 18 | 2.221788 | 0.026298 | Q92890,P42892,Q9BXW9,Q15427,P21964,Q9H0F7,Q96EK5,Q10713 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 642,102,693,602,146,352,541,55 | 1698,146,1397,2666,990,102,1466,1469,55,602,642,541,2282,693,352,889,699,1436 | -0.1560737352527625,1.733451983355156,-0.015949191785796384,-0.7323887974882097,0.19945282519176055,2.26843717639146,-0.043624015597528217,-0.043624015597528217,2.9114638007546514,0.5040506253802524,0.4794588708276966,0.5770071775774535,-0.4199119328370344,0.429857390182749,0.8797499948322487,0.2776008882438347,0.42985... | 3,120 |
Retinopathy | 9 | 26 | 2.207247 | 0.027297 | Q9NZ08,Q9NYB0,Q99496,P00846,O95169,O43819,P51648,Q15555,Q5H8A4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 100,361,524,9,444,295,47,393,248 | 1265,295,2502,1178,444,896,1040,9,1901,827,549,2554,2762,1087,1399,47,1523,2557,393,248,1611,2173,524,2705,361,100 | 0.03888935479482263,1.012646583383761,-0.6048009638951245,0.09305929398318494,0.6959550565518066,0.25170495959874245,0.1730932216945844,4.375070750907427,-0.24230752653304063,0.30334561141450944,0.5528233698913807,-0.6363634842619023,-0.8636557041179473,0.1465756160978675,-0.015949191785796384,3.0071390894611416,-0.071... | 3,120 |
Glycosyltransferase | 7 | 31 | 2.203805 | 0.027538 | Q13126,O43505,Q96L58,Q10472,P43490,Q9BT22,Q9H6U8 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 133,141,175,214,89,319,188 | 2249,141,858,2502,2684,2304,1902,1042,2071,1592,2019,1832,334,1340,89,1649,778,717,214,838,133,2701,2046,1100,175,319,1366,2117,188,1261,1944 | -0.4199119328370344,1.8424923729445961,0.2776008882438347,-0.6048009638951245,-0.764852983812969,-0.45020613666046194,-0.24230752653304063,0.1730932216945844,-0.33023269302803204,-0.09949469747666943,-0.3007325721587227,-0.21337800008247138,0.9021855262027676,0.011554613903006978,2.427254953547532,-0.12769463103528156,... | 3,120 |
Protein transmembrane transport | 12 | 24 | 2.203514 | 0.027559 | Q07820,Q9NS69,O60830,P31751,P49755,Q3ZCQ8,O75298,O14925,Q15388,Q15629,O95831,O43615 | Processes and pathways | GO Biological process | msigdb_gobp | 503,35,3,570,625,240,81,113,346,121,401,615 | 113,615,3070,3,81,1704,2069,401,1077,2802,570,625,2922,1659,2588,503,346,121,240,1553,1425,1569,35,673 | 2.1032619844886535,0.4794588708276966,-1.9889367176870343,5.022002691408248,2.5801554718278767,-0.1560737352527625,-0.33023269302803204,0.7657939331769242,0.1465756160978675,-0.9307313466100875,0.5285049852239486,0.4794588708276966,-1.1380519309620947,-0.12769463103528156,-0.6681470252093221,0.6249765506068089,0.879749... | 3,120 |
Cristae formation | 11 | 20 | 2.203428 | 0.027565 | O75947,O75431,P24539,Q9NX63,P00846,Q5XKP0,Q16891,O75964,P36542,Q13505,Q9Y512 | Processes and pathways | Reactome Pathways | msigdb_reactome | 568,618,129,757,9,270,603,52,711,88,459 | 618,568,52,9,766,129,1773,711,2667,2032,2632,1845,88,603,270,1300,2536,975,757,459 | 0.4794588708276966,0.5285049852239486,2.925271544766199,4.375070750907427,0.3543879449769868,1.9312396535039034,-0.18463413695639644,0.4048447144069418,-0.7323887974882097,-0.3007325721587227,-0.7001544799726708,-0.21337800008247138,2.4428044126478934,0.5040506253802524,1.0990194895203063,0.03888935479482263,-0.6048009... | 3,120 |
C4 dicarboxylate transport | 6 | 8 | 2.202676 | 0.027618 | Q9H936,Q8TDW0,O75746,Q9UJS0,Q02978,Q9UBX3 | Processes and pathways | GO Biological process | msigdb_gobp | 496,423,567,411,432,157 | 567,626,432,1415,423,496,157,411 | 0.5285049852239486,0.4794588708276966,0.7193596211985692,-0.015949191785796384,0.7426388328088186,0.6487648093812882,1.621506944075928,0.7657939331769242 | 3,120 |
Cellular modified amino acid metabolic process | 9 | 56 | 2.182051 | 0.029106 | P23786,Q9H7Z7,Q9H2D1,Q8NCC3,P00374,Q9BVG9,Q9UHG3,O60725,Q8IYS1 | Processes and pathways | GO Biological process | msigdb_gobp | 98,135,40,11,44,144,18,83,84 | 1823,2709,2578,858,83,1179,621,44,1388,2735,2252,1041,2985,1510,2346,2919,2759,899,327,2738,2687,98,1455,1964,1648,1130,1284,1775,204,1464,1596,2998,2626,2999,738,403,1663,2875,1148,2767,84,1062,11,2567,1307,1562,3066,1998,144,1213,40,135,697,331,18,728 | -0.21337800008247138,-0.7975501035896743,-0.6681470252093221,0.2776008882438347,2.550029118133312,0.09305929398318494,0.4794588708276966,3.087373369880343,-0.015949191785796384,-0.8304832815585822,-0.4199119328370344,0.1730932216945844,-1.3551362796599622,-0.07147184402573621,-0.4807050971530273,-1.1380519309620947,-0.... | 3,120 |
Limb muscle weakness | 16 | 85 | 2.179358 | 0.029305 | Q7RTS9,Q14739,Q15650,P35670,P50402,Q9BQT8,Q13126,Q13510,P00846,P50336,Q15067,Q9NR77,O75298,Q99720,P07196,P36551 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 196,195,291,255,290,101,133,71,9,170,300,80,81,20,119,127 | 1578,1378,587,2129,295,81,1899,429,9,1766,2505,862,985,119,2617,1450,2802,1079,1646,623,770,2808,2623,255,127,1189,1087,2082,2084,1966,170,290,1840,2207,1342,502,2630,1781,2764,2631,2519,1914,2591,2093,2398,2357,133,433,71,2162,1199,1200,2401,195,2790,300,1002,1793,291,1794,1474,1249,1731,196,2403,687,638,1741,1931,256... | -0.09949469747666943,-0.015949191785796384,0.5040506253802524,-0.3599276825042347,1.012646583383761,2.5801554718278767,-0.24230752653304063,0.7193596211985692,4.375070750907427,-0.18463413695639644,-0.6048009638951245,0.2776008882438347,0.19945282519176055,2.0181394542083764,-0.7001544799726708,-0.043624015597528217,-0... | 3,120 |
Steroid biosynthesis | 8 | 22 | 2.178105 | 0.029398 | Q16850,Q14739,P37268,Q15392,Q53GQ0,P04035,P48449,O75845 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 65,195,68,230,205,267,85,310 | 310,2616,267,402,68,85,1967,777,1664,2766,195,1541,230,1982,686,65,205,2107,887,1567,699,3061 | 0.9688011263013478,-0.7001544799726708,1.0990194895203063,0.7657939331769242,2.770727945453716,2.489102096014749,-0.2714249570573372,0.3543879449769868,-0.12769463103528156,-0.8636557041179473,1.388303199401113,-0.07147184402573621,1.2045970593385245,-0.2714249570573372,0.429857390182749,2.8134649963657146,1.3279431624... | 3,120 |
Phosphatidylinositol biosynthetic process | 8 | 20 | 2.173695 | 0.029728 | Q5H8A4,Q96S52,Q969N2,Q10713,Q9NX62,Q96N66,Q8TBX8,O00459 | Processes and pathways | GO Biological process | msigdb_gobp | 248,302,385,55,224,153,219,339 | 2755,339,2548,2502,2782,1183,381,999,55,248,665,219,640,385,153,1163,302,1999,1817,224 | -0.8636557041179473,0.8797499948322487,-0.6363634842619023,-0.6048009638951245,-0.8970706209351134,0.09305929398318494,0.8117366781974475,0.19945282519176055,2.9114638007546514,1.1626777008156755,0.45472828026538425,1.2667156015614143,0.4794588708276966,0.8117366781974475,1.640372274402174,0.11989823952072967,1.0126465... | 3,120 |
Mitochondrial complex iv assembly | 7 | 13 | 2.172895 | 0.029788 | P00403,Q9Y2R0,P20674,Q9Y6N1,P14406,Q7KZN9,P13073 | Processes and pathways | WikiPathways | msigdb_wp | 225,2,288,198,41,185,57 | 2062,295,225,864,2711,57,41,1771,288,185,3111,2,198 | -0.33023269302803204,1.012646583383761,1.2254037240919913,0.2776008882438347,-0.7975501035896743,2.897608649302585,3.139985047591634,-0.18463413695639644,1.0344030160862734,1.4280724450354945,-3.409934469339057,5.247956016095376,1.3682781678569051 | 3,120 |
Glycosaminoglycan metabolism | 6 | 15 | 2.171853 | 0.029867 | O43505,Q96L58,P15586,Q7LGA3,Q8NCH0,P54802 | Processes and pathways | Reactome Pathways | msigdb_reactome | 141,175,238,17,117,276 | 2299,141,2070,2618,591,238,476,276,838,17,117,369,175,1164,2572 | -0.45020613666046194,1.8424923729445961,-0.33023269302803204,-0.7001544799726708,0.5040506253802524,1.1836886940989366,0.6487648093812882,1.0775884567819758,0.30334561141450944,3.811591163952668,2.069421914151396,0.8345267182780652,1.487036333627781,0.11989823952072967,-0.6363634842619023 | 3,120 |
FAD/NAD(P)-binding domain superfamily [IPR036188] | 6 | 18 | 2.170284 | 0.029985 | Q9H9P8,P50336,Q16134,Q14534,Q9UHG3,Q96CU9 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 396,170,269,172,18,91 | 1502,401,1388,2428,2931,2808,1237,1462,170,1522,172,269,1796,534,813,91,396,18 | -0.07147184402573621,0.7657939331769242,-0.015949191785796384,-0.5423276822514903,-1.1735319573878251,-0.9307313466100875,0.06605695177290508,-0.043624015597528217,1.5065101151687854,-0.07147184402573621,1.487036333627781,1.0990194895203063,-0.18463413695639644,0.5770071775774535,0.32894076142978074,2.4116463573658264,... | 3,120 |
Incoordination | 17 | 72 | 2.16927 | 0.030062 | Q7RTS9,Q9NZJ7,O14773,Q13510,P21912,P00846,Q15067,O43819,Q9NR77,Q99707,Q9H0F7,O75503,Q10713,O95140,Q13501,Q01105,P35670 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 196,426,66,71,477,9,300,295,80,372,352,115,55,429,433,189,255 | 1225,2834,66,1034,2063,675,295,2197,617,115,2301,1271,429,1961,9,1902,985,1079,3002,477,2349,2808,2623,255,1189,1087,803,1519,1521,1342,502,2764,2631,2519,833,189,1346,1244,1194,55,433,71,2162,1200,300,1793,1151,843,1355,2220,196,2368,1303,1931,1063,815,2282,1482,1365,1164,372,2111,352,849,2980,80,1321,426,1172,2966,25... | 0.06605695177290508,-0.9646412623937256,2.7850237629841788,0.1730932216945844,-0.33023269302803204,0.429857390182749,1.012646583383761,-0.38981994606341763,0.4794588708276966,2.086376421063753,-0.45020613666046194,0.03888935479482263,0.7193596211985692,-0.2714249570573372,4.375070750907427,-0.24230752653304063,0.199452... | 3,120 |
Amide transport | 10 | 34 | 2.164914 | 0.030394 | Q9NZJ7,Q9H2D1,P53985,P41440,Q8N5M9,Q9NZD2,P08183,Q16836,P50416,Q15907 | Processes and pathways | GO Biological process | msigdb_gobp | 426,40,104,204,338,252,22,347,403,61 | 2576,1265,940,1893,569,1590,799,22,1043,1186,1905,2841,1087,204,403,104,2520,2091,2525,2718,1409,659,2160,61,2271,347,1301,338,436,3066,40,252,426,2241 | -0.6681470252093221,0.03888935479482263,0.22565616698772623,-0.24230752653304063,0.5285049852239486,-0.09949469747666943,0.32894076142978074,3.744867759885806,0.1730932216945844,0.09305929398318494,-0.24230752653304063,-0.9646412623937256,0.1465756160978675,1.3279431624639007,0.7657939331769242,2.186673620608435,-0.604... | 3,120 |
Muscle spasm | 12 | 62 | 2.163239 | 0.030523 | Q15165,Q9UQN3,P23786,P53985,P00846,P51530,Q9H6K4,Q9NR77,O75298,Q709C8,P07196,Q5H8A4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 1,162,98,104,9,297,111,80,81,307,119,248 | 1700,1955,2197,81,617,429,1588,2734,2251,9,1902,2505,862,898,1042,119,3055,1043,2428,1272,2985,1079,3088,98,1648,1239,1087,2082,1965,344,1841,297,104,502,1781,2764,2631,1346,1194,2399,433,1199,1,1474,248,2220,307,1560,1064,539,1482,1365,3066,1104,2910,111,849,80,563,162,2983,652 | -0.1560737352527625,-0.2714249570573372,-0.38981994606341763,2.5801554718278767,0.4794588708276966,0.7193596211985692,-0.09949469747666943,-0.8304832815585822,-0.4199119328370344,4.375070750907427,-0.24230752653304063,-0.6048009638951245,0.2776008882438347,0.25170495959874245,0.1730932216945844,2.0181394542083764,-1.78... | 3,120 |
Slender long bone | 7 | 12 | 2.155688 | 0.031108 | Q9Y487,P37268,Q96L58,Q32P28,Q96MF7,Q969N2,Q9H0W5 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 362,68,175,366,387,385,458 | 2462,68,480,1794,366,2675,385,175,387,458,1167,362 | -0.5734566251984043,2.770727945453716,0.6487648093812882,-0.18463413695639644,0.8345267182780652,-0.7323887974882097,0.8117366781974475,1.487036333627781,0.8117366781974475,0.6959550565518066,0.11989823952072967,0.8571974386256007 | 3,120 |
Fatty acid transport | 6 | 15 | 2.155372 | 0.031133 | P23786,P31751,O43808,P07814,O43772,P50416 | Processes and pathways | GO Biological process | msigdb_gobp | 98,570,332,14,15,403 | 15,332,1589,2735,799,14,2255,2142,98,1282,593,570,1131,403,1732 | 3.898819192738822,0.9021855262027676,-0.09949469747666943,-0.8304832815585822,0.32894076142978074,3.9095867503469988,-0.4199119328370344,-0.3599276825042347,2.3167291137840786,0.03888935479482263,0.5040506253802524,0.5285049852239486,0.11989823952072967,0.7657939331769242,-0.1560737352527625 | 3,120 |
Regulation of protein secretion | 15 | 38 | 2.147396 | 0.031762 | Q16850,O95486,P49755,P55011,O95563,Q15334,P53985,P04035,Q96KC8,Q8NE86,Q8N5M9,Q32P28,Q16836,P53367,P50416 | Processes and pathways | GO Biological process | msigdb_gobp | 65,217,625,626,569,575,104,267,211,436,338,366,347,245,403 | 1265,730,1893,2756,217,569,1590,267,1043,1275,1186,1905,1188,2841,1285,1087,625,403,245,104,626,2520,2525,2718,1723,1409,575,2271,347,65,366,1301,338,436,211,1482,694,1576 | 0.03888935479482263,0.37968874363881105,-0.24230752653304063,-0.8636557041179473,1.2667156015614143,0.5285049852239486,-0.09949469747666943,1.0990194895203063,0.1730932216945844,0.03888935479482263,0.09305929398318494,-0.24230752653304063,0.09305929398318494,-0.9646412623937256,0.03888935479482263,0.1465756160978675,0.... | 3,120 |
Hepatic failure | 6 | 48 | 2.140198 | 0.032339 | P23786,Q13510,P00846,O43772,Q10713,P22830 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 98,71,9,15,55,24 | 1891,112,15,3070,2300,1704,498,310,1642,9,1901,3014,1902,1333,2253,1507,2428,2663,24,98,1282,2665,255,3016,1461,1087,1709,403,502,2631,1849,55,2158,71,2271,347,1614,1354,1364,2909,1168,1815,1259,2539,758,2336,890,2610 | -0.24230752653304063,2.1200791235371135,3.898819192738822,-1.9889367176870343,-0.45020613666046194,-0.1560737352527625,0.6249765506068089,0.9688011263013478,-0.12769463103528156,4.375070750907427,-0.24230752653304063,-1.5057183812598571,-0.24230752653304063,0.011554613903006978,-0.4199119328370344,-0.07147184402573621,... | 3,120 |
Icosanoid metabolic process | 6 | 18 | 2.137527 | 0.032555 | Q8N8N7,Q9H7Z7,Q8NCG7,P07099,Q8N4Q0,P09960 | Processes and pathways | GO Biological process | msigdb_gobp | 69,135,301,10,278,213 | 548,799,10,213,2142,2620,2783,3010,300,2322,1062,278,69,301,1622,1998,135,1886 | 0.5528233698913807,0.32894076142978074,4.209515969875745,1.287222609209894,-0.3599276825042347,-0.7001544799726708,-0.8970706209351134,-1.4676135569727793,1.012646583383761,-0.45020613666046194,0.1730932216945844,1.0775884567819758,2.7130355927853143,1.012646583383761,-0.09949469747666943,-0.2714249570573372,1.89596650... | 3,120 |
Aplasia hypoplasia involving the vertebral column | 7 | 16 | 2.135197 | 0.032745 | Q7RTS9,Q14739,Q96HY6,Q8TAA9,P16278,P08236,O95831 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 196,195,558,134,476,591,401 | 1034,2550,401,1124,591,1273,476,1458,595,195,1982,1614,196,134,558,1815 | 0.1730932216945844,-0.6363634842619023,0.7657939331769242,0.11989823952072967,0.5040506253802524,0.03888935479482263,0.6487648093812882,-0.043624015597528217,0.5040506253802524,1.388303199401113,-0.2714249570573372,-0.09949469747666943,1.388303199401113,1.8959665059951594,0.5528233698913807,-0.18463413695639644 | 3,120 |
Proton transmembrane transport | 11 | 46 | 2.131995 | 0.033007 | P24539,P00403,Q9UDW1,P36543,O14548,P00846,Q8TAD4,O75964,Q7KZN9,Q13423,P13073 | Processes and pathways | GO Biological process | msigdb_gobp | 129,225,36,262,199,9,208,52,185,246,57 | 2062,199,940,1763,2930,568,52,225,9,3014,862,1229,766,1507,2711,1079,57,288,1081,769,129,1773,3090,2309,711,262,1460,2814,2032,1842,2632,1845,2433,1720,1469,246,185,208,3066,454,1164,496,36,2572,1572,853 | -0.33023269302803204,1.3481584340693418,0.22565616698772623,-0.18463413695639644,-1.1735319573878251,0.5285049852239486,2.925271544766199,1.2254037240919913,4.375070750907427,-1.5057183812598571,0.2776008882438347,0.06605695177290508,0.3543879449769868,-0.07147184402573621,-0.7975501035896743,0.1465756160978675,2.89760... | 3,120 |
Sterol biosynthetic process | 9 | 26 | 2.119115 | 0.034081 | Q16850,Q14739,P37268,P16435,Q15392,P04035,Q14534,P48449,O75845 | Processes and pathways | GO Biological process | msigdb_gobp | 65,195,68,327,230,267,172,85,310 | 588,310,1899,2616,267,1510,402,327,68,2391,85,1843,1967,777,1664,600,2766,172,195,1541,230,1982,686,65,699,3061 | 0.5040506253802524,0.9688011263013478,-0.24230752653304063,-0.7001544799726708,1.0990194895203063,-0.07147184402573621,0.7657939331769242,0.9245051560552161,2.770727945453716,-0.5114114008305259,2.489102096014749,-0.21337800008247138,-0.2714249570573372,0.3543879449769868,-0.12769463103528156,0.5040506253802524,-0.8636... | 3,120 |
Polydactyly | 19 | 43 | 2.117724 | 0.034198 | O60826,Q8NCM8,P21964,Q13045,Q9BXW9,Q15067,Q9UBM7,Q9UM00,Q10713,Q9UHX1,O75845,Q14739,O43924,Q9H0F7,O00459,Q92890,Q86XI2,Q8IY17,Q5H8A4 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 391,667,146,405,693,300,699,441,55,583,310,195,79,352,339,642,484,638,248 | 339,1698,79,391,310,896,1040,1235,2806,146,1514,1397,2629,1466,683,870,837,55,405,2557,195,1980,300,248,1735,484,638,1805,667,2724,642,1563,2332,2000,693,352,1017,2980,699,583,1111,441,1886 | 0.8797499948322487,-0.1560737352527625,2.610061135094578,0.7888261461963076,0.9688011263013478,0.25170495959874245,0.1730932216945844,0.06605695177290508,-0.9307313466100875,1.733451983355156,-0.07147184402573621,-0.015949191785796384,-0.7001544799726708,-0.043624015597528217,0.429857390182749,0.2776008882438347,0.3033... | 3,120 |
Rac2 gtpase cycle | 7 | 32 | 2.108524 | 0.034986 | Q14739,P42167,P50402,Q8TAA9,Q13505,O00459,Q86XL3 | Processes and pathways | Reactome Pathways | msigdb_reactome | 195,226,290,134,88,339,95 | 339,2136,1588,2427,825,1768,906,226,1286,1192,290,2207,1289,2471,2159,1790,88,2359,551,195,1928,2217,1302,95,134,1626,1680,1491,1264,2339,796,459 | 0.8797499948322487,-0.3599276825042347,-0.09949469747666943,-0.5423276822514903,0.30334561141450944,-0.18463413695639644,0.25170495959874245,1.2254037240919913,0.03888935479482263,0.09305929398318494,1.0344030160862734,-0.38981994606341763,0.03888935479482263,-0.5734566251984043,-0.3599276825042347,-0.18463413695639644... | 3,120 |
Phospholipid biosynthetic process | 21 | 54 | 2.107342 | 0.035088 | O95749,Q9NPH0,Q86YN1,Q9BVG9,Q9NPH2,Q96N66,Q8NF37,P14324,Q96S52,P35790,Q6IAN0,Q10713,O15269,Q8TBX8,O00459,Q9NX62,Q92643,Q6UWP7,Q5H8A4,Q969N2,P42356 | Processes and pathways | GO Biological process | msigdb_gobp | 622,6,666,144,543,153,537,402,302,42,553,55,587,219,339,224,640,506,248,385,381 | 2755,339,2548,703,587,2129,2502,1179,1589,764,622,2782,1183,2618,402,2074,1905,42,381,2998,1967,1664,999,55,2766,1541,248,553,506,665,1550,666,537,219,1560,1010,640,385,153,1163,302,1164,2489,1999,144,788,6,543,1817,2776,224,2241,978,2572 | -0.8636557041179473,0.8797499948322487,-0.6363634842619023,0.4048447144069418,0.5040506253802524,-0.3599276825042347,-0.6048009638951245,0.09305929398318494,-0.09949469747666943,0.3543879449769868,0.4794588708276966,-0.8970706209351134,0.09305929398318494,-0.7001544799726708,0.7657939331769242,-0.33023269302803204,-0.2... | 3,120 |
Abnormal lung lobation | 6 | 12 | 2.103256 | 0.035443 | Q14739,Q92890,P21964,Q969N2,Q9H6U8,Q9UHX1 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 195,642,146,385,188,583 | 2196,1382,146,1466,195,871,642,1308,385,188,699,583 | -0.38981994606341763,-0.015949191785796384,1.733451983355156,-0.043624015597528217,1.388303199401113,0.2776008882438347,0.4794588708276966,0.03888935479482263,0.8117366781974475,1.4280724450354945,0.429857390182749,0.5285049852239486 | 3,120 |
Peptidase activity | 32 | 111 | 2.097639 | 0.035937 | Q7Z2K6,P28074,P20618,Q9UIQ6,P42785,O75844,P22695,Q9HB40,Q5JRX3,Q9BYT8,Q4J6C6,P28072,Q9H3G5,P55786,Q10713,O14773,Q8TCT9,P10619,Q16740,Q8IYS1,P09960,Q99436,Q0VDG4,P28070,Q96RU2,O43847,Q9NZ08,P42892,Q96K76,Q92542,P49721,P36551 | Functions | GO Molecular function | msigdb_gomf | 257,378,377,132,7,13,274,32,160,425,39,418,43,54,55,66,325,200,201,84,213,465,93,221,492,220,100,102,371,370,120,127 | 1442,1116,66,473,1955,220,2458,13,1122,1765,860,945,825,2617,213,200,2803,2736,1274,2074,377,274,2904,221,418,378,2585,2622,2512,127,1458,7,102,1913,907,1713,120,1653,1654,1779,1655,1780,1715,2262,54,1090,1135,2746,93,55,2923,2158,2440,2697,2594,201,39,1543,160,2529,1615,3057,2221,257,1863,1551,84,325,878,370,640,1562,... | -0.043624015597528217,0.11989823952072967,2.7850237629841788,0.6487648093812882,-0.2714249570573372,1.2461096037129336,-0.5734566251984043,3.9629821531008274,0.11989823952072967,-0.18463413695639644,0.2776008882438347,0.22565616698772623,0.30334561141450944,-0.7001544799726708,1.287222609209894,1.3481584340693418,-0.93... | 3,120 |
MFS transporter superfamily [IPR036259] | 6 | 9 | 2.094875 | 0.036182 | Q6N075,P53985,P41440,Q9NY64,Q99808,Q14728 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 324,104,204,438,242,58 | 2255,204,104,58,576,324,2173,242,438 | -0.4199119328370344,1.3279431624639007,2.186673620608435,2.8837057870744482,0.5285049852239486,0.9467099920148521,-0.3599276825042347,1.1836886940989366,0.7193596211985692 | 3,120 |
Abnormality of visual evoked potentials | 8 | 21 | 2.0941 | 0.036251 | Q9NZJ7,Q9H936,Q15067,Q86YH6,Q9GZY8,O75503,O95140,O60313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 426,496,300,328,207,115,429,340 | 675,340,115,429,502,1717,1246,1981,300,2368,328,1556,1063,815,207,1167,496,1217,2240,426,2607 | 0.429857390182749,0.8797499948322487,2.086376421063753,0.7193596211985692,0.6249765506068089,-0.1560737352527625,0.06605695177290508,-0.2714249570573372,1.012646583383761,-0.4807050971530273,0.9245051560552161,-0.07147184402573621,0.1730932216945844,0.32894076142978074,1.3279431624639007,0.11989823952072967,0.648764809... | 3,120 |
Carbohydrate derivative catabolic process | 17 | 36 | 2.090481 | 0.036575 | P36639,Q8N335,Q13126,Q9H773,O60502,P16278,P17900,P15586,Q9NUJ1,Q9BW91,Q9BTY2,P35610,P54802,A8MXV4,P00813,P13051,P49902 | Processes and pathways | GO Biological process | msigdb_gobp | 64,507,133,167,443,476,268,238,282,308,610,122,276,181,273,285,222 | 181,1441,443,2684,2304,273,1902,1124,898,2070,2618,591,285,238,476,268,2739,2624,3089,122,64,1518,2517,222,276,1665,133,507,1100,1310,610,308,2880,167,282,2545 | 1.4478182777817359,-0.043624015597528217,0.6959550565518066,-0.764852983812969,-0.45020613666046194,1.0775884567819758,-0.24230752653304063,0.11989823952072967,0.25170495959874245,-0.33023269302803204,-0.7001544799726708,0.5040506253802524,1.0560499674593824,1.1836886940989366,0.6487648093812882,1.0990194895203063,-0.8... | 3,120 |
Predicted secreted proteins | 13 | 51 | 2.088812 | 0.036725 | P84157,Q15165,Q9HB40,O60888,Q9NZ08,Q9UM22,Q92520,P80303,Q8N128,Q08380,P43490,Q02818,Q9UMX5 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 256,1,32,193,100,37,233,12,337,148,89,26,27 | 2340,3099,858,193,619,1585,1447,825,799,984,1389,3071,1232,2142,1274,735,2464,947,1085,89,2906,1524,3106,3074,1847,12,2746,256,26,345,148,659,1724,2592,1,337,2924,3041,233,3019,1103,786,610,2536,2898,849,32,100,37,27,729 | -0.4807050971530273,-2.671736994716146,0.2776008882438347,1.388303199401113,0.4794588708276966,-0.09949469747666943,-0.043624015597528217,0.30334561141450944,0.32894076142978074,0.19945282519176055,-0.015949191785796384,-1.9889367176870343,0.06605695177290508,-0.3599276825042347,0.03888935479482263,0.37968874363881105,... | 3,120 |
Amino acid transmembrane transport | 8 | 14 | 2.084356 | 0.037128 | Q9H936,Q9H9B4,Q8TDW0,O75746,O75915,P08195,Q9UJS0,P30825 | Processes and pathways | GO Biological process | msigdb_gobp | 496,526,423,567,621,767,411,126 | 1640,567,621,1768,767,126,1296,1415,423,882,1683,496,526,411 | -0.12769463103528156,0.5285049852239486,0.4794588708276966,-0.18463413695639644,0.3543879449769868,1.9662172504490403,0.03888935479482263,-0.015949191785796384,0.7426388328088186,0.2776008882438347,-0.12769463103528156,0.6487648093812882,0.6010577855594291,0.7657939331769242 | 3,120 |
Muscle stiffness | 7 | 18 | 2.07471 | 0.038013 | Q9NZJ7,P23786,P53985,P00846,Q15392,Q9NW15,P49748 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 426,98,104,9,230,410,344 | 676,2734,9,985,2255,98,344,1523,104,502,2519,2398,230,1355,2224,410,426,2545 | 0.429857390182749,-0.8304832815585822,4.375070750907427,0.19945282519176055,-0.4199119328370344,2.3167291137840786,0.8797499948322487,-0.07147184402573621,2.186673620608435,0.6249765506068089,-0.6048009638951245,-0.5114114008305259,1.2045970593385245,0.011554613903006978,-0.38981994606341763,0.7657939331769242,0.742638... | 3,120 |
Transporter activity | 67 | 167 | 2.064214 | 0.038997 | Q07820,P24539,P38435,O60830,Q9H9B4,P36543,Q9HD20,P00846,P17900,O43772,P21796,Q93050,Q9UJS0,P08183,Q9NW15,P30536,O95168,Q8WTV0,Q9UBX3,Q9NS69,Q9UDW1,Q9Y6M9,P20674,Q8TDW0,Q9H2D1,Q9P0J0,Q9BXB4,Q9UM00,Q8IXU6,Q9NY64,O96000,Q8NE86,O75964,Q02978,P13073,Q14728,Q7KZN9,Q9Y3B1,O75947,Q6N075,P45880,O95563,O14548,P20020,O95169,P4144... | Functions | GO Molecular function | msigdb_gomf | 503,129,500,3,526,262,136,9,268,15,16,279,411,22,410,25,529,30,157,35,36,565,288,423,40,561,303,441,49,438,178,436,52,432,57,58,185,585,568,324,70,569,199,447,444,204,332,78,208,460,346,225,362,496,101,104,369,110,239,112,113,242,368,252,246,126,255 | 3038,3021,1823,2062,199,940,113,112,3104,675,15,332,2780,3,460,2930,1178,2551,1385,567,568,52,2069,529,444,1587,896,2503,569,178,1077,225,9,3014,1902,862,1332,1229,766,3044,1389,2345,22,767,1507,2968,2711,2255,1079,1335,57,239,268,2584,447,288,1081,769,16,1905,1706,129,1773,1282,2147,25,126,2309,255,711,262,500,1460,20... | -1.6613267134213334,-1.5441372114598413,-0.21337800008247138,-0.33023269302803204,1.3481584340693418,0.22565616698772623,2.1032619844886535,2.1200791235371135,-2.9227381542310105,0.429857390182749,3.898819192738822,0.9021855262027676,-0.8970706209351134,5.022002691408248,0.6724238788270614,-1.1735319573878251,0.0930592... | 3,120 |
Lipid homeostasis | 10 | 24 | 2.059638 | 0.039433 | Q96CP7,Q15067,O15118,Q9NQC3,Q5BJF2,Q9BWH2,P35610,O95486,P28340,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 235,300,112,212,53,251,122,217,311,30 | 823,112,762,321,217,1904,311,122,777,3074,3102,300,53,2217,3059,30,235,1622,251,647,212,1173,1373,427 | 0.30334561141450944,2.1200791235371135,0.3543879449769868,0.9467099920148521,1.2667156015614143,-0.24230752653304063,0.9688011263013478,2.0009038654063014,0.3543879449769868,-1.9889367176870343,-2.7705823045491824,1.012646583383761,2.925271544766199,-0.38981994606341763,-1.7815233696066426,3.4053666094719595,1.20459705... | 3,120 |
Protein transmembrane transporter activity | 6 | 10 | 2.054314 | 0.039945 | Q07820,O60830,Q9NS69,P49755,O14925,Q15388 | Functions | GO Molecular function | msigdb_gomf | 503,3,35,625,113,346 | 113,3,2069,1077,625,2588,503,346,35,673 | 2.1032619844886535,5.022002691408248,-0.33023269302803204,0.1465756160978675,0.4794588708276966,-0.6681470252093221,0.6249765506068089,0.8797499948322487,3.255890605195437,0.45472828026538425 | 3,120 |
er | 25 | 89 | 2.052317 | 0.040139 | Q06136,Q8NHH9,Q8NC56,Q9Y5M8,Q9BVG9,Q9NPA0,Q96N66,O75845,Q16850,Q14739,O00264,Q9P2W9,Q07065,Q9NQC3,P48449,Q8TBX8,Q9Y487,P51572,O95470,Q15392,Q8N4V1,Q969Q5,O60499,O96005,Q12981 | Localization | OpenCell Localization | opencell_localization | 130,258,138,140,144,409,153,310,65,195,191,73,75,212,85,219,362,354,107,230,368,116,243,244,382 | 191,3022,2548,2885,587,2129,2994,243,617,1503,310,621,1588,107,764,244,1183,2616,765,1643,2140,2256,1455,2024,988,1649,85,2998,625,2935,354,2764,2922,1659,1291,1660,2089,2155,2634,130,75,382,1853,195,920,1296,809,230,1982,1542,65,812,921,1732,2642,1550,368,1556,138,537,258,219,1100,2925,2406,116,785,463,3048,153,1997,1... | 1.388303199401113,-1.5441372114598413,-0.6363634842619023,-1.0679010003564908,0.5040506253802524,-0.3599276825042347,-1.3923270876756626,1.1626777008156755,0.4794588708276966,-0.07147184402573621,0.9688011263013478,0.4794588708276966,-0.09949469747666943,2.1535101765609372,0.3543879449769868,1.1626777008156755,0.093059... | 3,120 |
Vacuole organization | 9 | 55 | 2.044608 | 0.040894 | Q9UQN3,O14773,P11117,Q14108,P16615,P50897,O75503,Q9Y3E7,Q8TBX8 | Processes and pathways | GO Biological process | msigdb_gobp | 162,66,97,105,239,48,115,253,219 | 1497,66,2067,1503,115,1271,429,589,1902,1389,2618,1593,97,239,768,680,908,48,2207,276,1193,869,2091,1975,105,1981,601,1004,2217,1552,2173,219,2406,1159,3048,2940,1482,790,373,2116,1167,1018,2119,1170,2188,563,1111,2057,1025,162,1887,1031,253,1758,2294 | -0.07147184402573621,2.7850237629841788,-0.33023269302803204,-0.07147184402573621,2.086376421063753,0.03888935479482263,0.7193596211985692,0.5040506253802524,-0.24230752653304063,-0.015949191785796384,-0.7001544799726708,-0.09949469747666943,2.3167291137840786,1.1836886940989366,0.3543879449769868,0.429857390182749,0.2... | 3,120 |
O acyltransferase activity | 6 | 12 | 2.040689 | 0.041282 | P23786,Q8NCC3,Q6UWP7,Q96N66,P50416,P35610 | Functions | GO Molecular function | msigdb_gomf | 98,11,506,153,403,122 | 703,98,2203,122,403,506,1550,11,537,153,2489,2776 | 0.4048447144069418,2.3167291137840786,-0.38981994606341763,2.0009038654063014,0.7657939331769242,0.6249765506068089,-0.07147184402573621,4.159435423734304,0.5770071775774535,1.640372274402174,-0.5734566251984043,-0.8636557041179473 | 3,120 |
Glycoprotein metabolic process | 14 | 58 | 2.04039 | 0.041312 | Q96JB2,Q99805,O60476,O43505,Q96L58,Q9H0U4,O15118,Q7LGA3,Q8NCH0,Q10472,P35610,Q9BT22,Q9H6U8,Q9NX62 | Processes and pathways | GO Biological process | msigdb_gobp | 96,131,192,141,175,373,112,17,117,214,122,319,188,224 | 2709,112,2249,141,192,443,858,1639,2502,2995,617,2581,765,1643,2804,3089,2080,122,988,1649,2089,2091,2397,2093,1469,1194,2526,717,214,838,1246,1144,2560,1004,720,17,2701,666,117,1100,370,96,175,3066,1164,131,319,1366,1066,373,2117,694,188,849,224,1882,1261,2572 | -0.7975501035896743,2.1200791235371135,-0.4199119328370344,1.8424923729445961,1.388303199401113,0.6959550565518066,0.2776008882438347,-0.12769463103528156,-0.6048009638951245,-1.3923270876756626,0.4794588708276966,-0.6681470252093221,0.3543879449769868,-0.12769463103528156,-0.9307313466100875,-2.2504606922272252,-0.330... | 3,120 |
Regulation of lipid biosynthetic process | 10 | 26 | 2.038479 | 0.041502 | P49748,Q13510,P16435,Q9UBM7,P11802,Q12770,O75477,P30536,Q8NF37,Q8WTV0 | Processes and pathways | GO Biological process | msigdb_gobp | 344,71,327,699,549,600,588,25,537,30 | 2012,588,1179,1899,1589,799,862,549,327,2074,25,2666,680,344,2432,1665,600,71,1730,537,30,1622,1164,699,2572,2337 | -0.3007325721587227,0.5040506253802524,0.09305929398318494,-0.24230752653304063,-0.09949469747666943,0.32894076142978074,0.2776008882438347,0.5528233698913807,0.9245051560552161,-0.33023269302803204,3.607914396820148,-0.7323887974882097,0.429857390182749,0.8797499948322487,-0.5423276822514903,-0.12769463103528156,0.504... | 3,120 |
Phosphatidylinositol metabolic process | 11 | 22 | 2.02973 | 0.042384 | Q5H8A4,Q96S52,Q6UWP7,Q92643,Q969N2,Q10713,Q9NX62,Q96N66,Q8TBX8,O00459,P42356 | Processes and pathways | GO Biological process | msigdb_gobp | 248,302,506,640,385,55,224,153,219,339,381 | 2755,339,2548,2502,2782,1183,1594,381,999,55,248,506,665,219,640,385,153,1163,302,1999,1817,224 | -0.8636557041179473,0.8797499948322487,-0.6363634842619023,-0.6048009638951245,-0.8970706209351134,0.09305929398318494,-0.09949469747666943,0.8117366781974475,0.19945282519176055,2.9114638007546514,1.1626777008156755,0.6249765506068089,0.45472828026538425,1.2667156015614143,0.4794588708276966,0.8117366781974475,1.64037... | 3,120 |
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