term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholesterol metabolism with bloch and kandutschrussell pathways
| 10
| 25
| 2.60039
| 0.009312
|
Q14739,Q16850,P37268,Q15392,P04035,Q14534,P48449,P14324,P35610,O75845
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
195,65,68,230,267,172,85,402,122,310
|
3022,1893,310,1589,622,677,267,402,1131,122,68,85,1399,1967,1664,2766,172,195,1541,230,1982,686,65,456,699
|
-1.5441372114598413,-0.24230752653304063,0.9688011263013478,-0.09949469747666943,0.4794588708276966,0.429857390182749,1.0990194895203063,0.7657939331769242,0.11989823952072967,2.0009038654063014,2.770727945453716,2.489102096014749,-0.015949191785796384,-0.2714249570573372,-0.12769463103528156,-0.8636557041179473,1.487036333627781,1.388303199401113,-0.07147184402573621,1.2045970593385245,-0.2714249570573372,0.429857390182749,2.8134649963657146,0.6959550565518066,0.429857390182749
| 3,120
|
Hand polydactyly
| 17
| 31
| 2.596465
| 0.009419
|
Q14739,Q92890,Q5H8A4,Q9BXW9,Q8IY17,Q15067,O60826,Q9UM00,Q8NCM8,O43924,P21964,Q9H0F7,Q10713,Q13045,Q9UHX1,O00459,O75845
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
195,642,248,693,638,300,391,441,667,79,146,352,55,405,583,339,310
|
339,1698,79,391,310,896,1040,2806,146,1397,1466,870,55,405,2557,195,1980,300,248,638,667,642,2000,693,352,2980,699,583,1111,441,1886
|
0.8797499948322487,-0.1560737352527625,2.610061135094578,0.7888261461963076,0.9688011263013478,0.25170495959874245,0.1730932216945844,-0.9307313466100875,1.733451983355156,-0.015949191785796384,-0.043624015597528217,0.2776008882438347,2.9114638007546514,0.7657939331769242,-0.6363634842619023,1.388303199401113,-0.2714249570573372,1.012646583383761,1.1626777008156755,0.4794588708276966,0.45472828026538425,0.4794588708276966,-0.2714249570573372,0.429857390182749,0.8797499948322487,-1.3182411457175676,0.429857390182749,0.5285049852239486,0.1465756160978675,0.7193596211985692,-0.21337800008247138
| 3,120
|
Molecular transducer activity
| 7
| 32
| 2.588876
| 0.009629
|
Q15629,P20645,Q14108,O15118,Q99720,P30536,Q8WTV0
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
121,165,105,112,20,25,30
|
3099,320,112,1271,1768,3044,1390,1451,165,25,2762,989,1399,807,1347,1724,105,1414,121,1415,959,2938,30,748,1425,20,1165,671,2928,512,673,184
|
-2.671736994716146,0.9467099920148521,2.1200791235371135,0.03888935479482263,-0.18463413695639644,-1.7411148495013815,-0.015949191785796384,-0.043624015597528217,1.5451910091391072,3.607914396820148,-0.8636557041179473,0.19945282519176055,-0.015949191785796384,0.32894076142978074,0.011554613903006978,-0.1560737352527625,2.186673620608435,-0.015949191785796384,2.0181394542083764,-0.015949191785796384,0.22565616698772623,-1.1735319573878251,3.4053666094719595,0.37968874363881105,-0.015949191785796384,3.80054934068688,0.11989823952072967,0.45472828026538425,-1.1380519309620947,0.6249765506068089,0.45472828026538425,1.4478182777817359
| 3,120
|
Disproportionate short limb short stature
| 12
| 20
| 2.569559
| 0.010183
|
Q7RTS9,Q14739,O75718,Q6DKJ4,Q15392,Q9UBM7,Q8NCM8,Q7LGA3,P42345,Q32P28,Q96MF7,Q9H6U8
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
196,195,619,394,230,699,667,17,680,366,387,188
|
939,703,2550,619,1273,2464,680,992,1978,195,230,366,394,17,196,667,387,1366,188,699
|
0.22565616698772623,0.4048447144069418,-0.6363634842619023,0.4794588708276966,0.03888935479482263,-0.5734566251984043,0.429857390182749,0.19945282519176055,-0.2714249570573372,1.388303199401113,1.2045970593385245,0.8345267182780652,0.7888261461963076,3.811591163952668,1.388303199401113,0.45472828026538425,0.8117366781974475,0.011554613903006978,1.4280724450354945,0.429857390182749
| 3,120
|
Organophosphate ester transport
| 9
| 26
| 2.561447
| 0.010424
|
Q9H2D1,Q14108,Q8TB61,P41440,O43808,Q99808,Q9NZD2,P08183,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
40,105,369,204,332,242,252,22,30
|
332,1229,22,1079,1335,1905,1963,204,1712,3074,1665,1347,105,2272,1670,369,423,30,3048,242,1213,40,1432,252,2241,585
|
0.9021855262027676,0.06605695177290508,3.744867759885806,0.1465756160978675,0.011554613903006978,-0.24230752653304063,-0.2714249570573372,1.3279431624639007,-0.1560737352527625,-1.9889367176870343,-0.12769463103528156,0.011554613903006978,2.186673620608435,-0.4199119328370344,-0.12769463103528156,0.8345267182780652,0.7426388328088186,3.4053666094719595,-1.7411148495013815,1.1836886940989366,0.09305929398318494,3.1530306783954622,-0.015949191785796384,1.1626777008156755,-0.38981994606341763,0.5285049852239486
| 3,120
|
Insulin resistance
| 9
| 18
| 2.557363
| 0.010547
|
P31751,P17096,Q8NC56,O95140,O75844,Q9H0F7,Q96MF7,P28340,O76024
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
570,446,138,429,13,352,387,311,254
|
1326,1265,618,13,254,429,1766,446,1452,311,570,2762,1462,952,138,387,352,1033
|
0.011554613903006978,0.03888935479482263,0.4794588708276966,3.9629821531008274,1.1415631395121968,0.7193596211985692,-0.18463413695639644,0.6959550565518066,-0.043624015597528217,0.9688011263013478,0.5285049852239486,-0.8636557041179473,-0.043624015597528217,0.22565616698772623,1.8782176443063971,0.8117366781974475,0.8797499948322487,0.19945282519176055
| 3,120
|
HAD superfamily [IPR023214]
| 8
| 21
| 2.557129
| 0.010554
|
P78330,P35670,Q9HD20,P16615,Q3ZCQ8,Q969T7,Q9H0P0,P49902
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
322,255,136,239,240,50,457,222
|
2457,862,239,447,1706,255,222,322,2436,1469,240,1927,784,689,50,1255,788,457,1814,1319,136
|
-0.5734566251984043,0.2776008882438347,1.1836886940989366,0.6959550565518066,-0.1560737352527625,1.1415631395121968,1.2461096037129336,0.9467099920148521,-0.5423276822514903,-0.043624015597528217,1.1836886940989366,-0.24230752653304063,0.3543879449769868,0.429857390182749,2.9664133235537427,0.06605695177290508,0.3543879449769868,0.6959550565518066,-0.18463413695639644,0.03888935479482263,1.8959665059951594
| 3,120
|
HAD-like superfamily [IPR036412]
| 8
| 21
| 2.557129
| 0.010554
|
P78330,P35670,Q9HD20,P16615,Q3ZCQ8,Q969T7,Q9H0P0,P49902
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
322,255,136,239,240,50,457,222
|
2457,862,239,447,1706,255,222,322,2436,1469,240,1927,784,689,50,1255,788,457,1814,1319,136
|
-0.5734566251984043,0.2776008882438347,1.1836886940989366,0.6959550565518066,-0.1560737352527625,1.1415631395121968,1.2461096037129336,0.9467099920148521,-0.5423276822514903,-0.043624015597528217,1.1836886940989366,-0.24230752653304063,0.3543879449769868,0.429857390182749,2.9664133235537427,0.06605695177290508,0.3543879449769868,0.6959550565518066,-0.18463413695639644,0.03888935479482263,1.8959665059951594
| 3,120
|
Mitochondrial protein import
| 13
| 34
| 2.541404
| 0.011041
|
Q5JRX3,O60830,Q9NS69,Q96B49,Q8N4H5,P21796,Q3ZCQ8,O14925,Q9UJS0,Q10713,Q13505,Q9Y512,Q15388
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,3,35,264,72,16,240,113,411,55,88,459,346
|
113,615,3,2870,618,2458,567,2069,444,1077,766,1507,2802,1079,1335,16,1773,2667,55,88,346,240,160,72,264,2990,1569,35,757,411,1027,459,2833,3105
|
2.1032619844886535,0.4794588708276966,5.022002691408248,-1.033222533253154,0.4794588708276966,-0.5734566251984043,0.5285049852239486,-0.33023269302803204,0.6959550565518066,0.1465756160978675,0.3543879449769868,-0.07147184402573621,-0.9307313466100875,0.1465756160978675,0.011554613903006978,3.844530607020698,-0.18463413695639644,-0.7323887974882097,2.9114638007546514,2.4428044126478934,0.8797499948322487,1.1836886940989366,1.5835213327153648,2.683879218936928,1.120344057573255,-1.3551362796599622,-0.07147184402573621,3.255890605195437,0.37968874363881105,0.7657939331769242,0.19945282519176055,0.6959550565518066,-0.9307313466100875,-3.079808520036465
| 3,120
|
Aminoglycan metabolic process
| 6
| 16
| 2.540123
| 0.011081
|
O43505,Q96L58,P15586,Q7LGA3,Q8NCH0,Q9NX62
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
141,175,238,17,117,224
|
141,1639,2460,1124,2070,2618,591,238,476,276,1405,838,17,117,175,224
|
1.8424923729445961,-0.12769463103528156,-0.5734566251984043,0.11989823952072967,-0.33023269302803204,-0.7001544799726708,0.5040506253802524,1.1836886940989366,0.6487648093812882,1.0775884567819758,-0.015949191785796384,0.30334561141450944,3.811591163952668,2.069421914151396,1.487036333627781,1.2461096037129336
| 3,120
|
Lysosomal lumen
| 11
| 33
| 2.533219
| 0.011302
|
O14773,P11117,Q9UM22,Q13510,P10619,Q14108,Q8IV08,P17900,P15586,P50897,Q8NHP8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
66,97,37,71,200,105,232,268,238,48,90
|
2340,66,675,1902,1124,898,2070,2618,1230,591,1593,200,97,1644,3088,238,476,268,500,3016,2084,48,276,3074,71,105,232,2856,90,1257,426,37,2543
|
-0.4807050971530273,2.7850237629841788,0.429857390182749,-0.24230752653304063,0.11989823952072967,0.25170495959874245,-0.33023269302803204,-0.7001544799726708,0.06605695177290508,0.5040506253802524,-0.09949469747666943,1.3481584340693418,2.3167291137840786,-0.12769463103528156,-2.2504606922272252,1.1836886940989366,0.6487648093812882,1.0990194895203063,0.6249765506068089,-1.5057183812598571,-0.33023269302803204,2.993609575094583,1.0775884567819758,-1.9889367176870343,2.683879218936928,2.186673620608435,1.2045970593385245,-0.9988038179626447,2.427254953547532,0.06605695177290508,0.7426388328088186,3.204791775087714,-0.6048009638951245
| 3,120
|
Slc mediated transmembrane transport
| 9
| 24
| 2.519969
| 0.011737
|
P53985,Q8TB61,Q70HW3,P35613,Q9NY64,Q8TAD4,Q99808,Q9UBX3,P30825
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
104,369,110,143,438,208,242,157,126
|
1229,767,2255,1079,1335,2841,126,143,2310,104,626,2672,1415,1732,110,208,369,1010,242,1683,496,438,157,1175
|
0.06605695177290508,0.3543879449769868,-0.4199119328370344,0.1465756160978675,0.011554613903006978,-0.9646412623937256,1.9662172504490403,1.788326470466217,-0.45020613666046194,2.186673620608435,0.4794588708276966,-0.7323887974882097,-0.015949191785796384,-0.1560737352527625,2.1368283516262,1.3076315066448148,0.8345267182780652,0.19945282519176055,1.1836886940989366,-0.12769463103528156,0.6487648093812882,0.7193596211985692,1.621506944075928,0.11989823952072967
| 3,120
|
Phospholipid binding
| 18
| 83
| 2.514031
| 0.011936
|
O14773,Q9NZJ7,Q9UM22,P45880,Q14108,Q8NCC3,P21796,P50897,Q9H0F7,Q9Y2I1,Q9Y3E7,Q9NZD2,Q9BWH2,Q13045,P53367,Q9Y4G8,O60313,Q8WTV0
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
66,426,37,70,105,11,16,48,352,180,253,252,251,405,245,125,340,30
|
822,2755,1227,66,1379,2063,2249,1443,340,1075,428,3013,1177,799,1389,3055,2345,1232,1591,1644,2757,1045,1127,770,16,1905,1338,2920,1189,70,1191,1286,1712,48,1841,245,1531,1143,405,1198,953,2161,105,1146,2479,2269,552,601,1862,1549,1553,1617,11,2277,30,927,640,1012,928,1311,1748,1626,251,1213,352,1680,694,252,426,3006,2829,853,2122,37,1693,980,180,253,1949,125,2294,2982,674
|
0.30334561141450944,-0.8636557041179473,0.06605695177290508,2.7850237629841788,-0.015949191785796384,-0.33023269302803204,-0.4199119328370344,-0.043624015597528217,0.8797499948322487,0.1465756160978675,0.7193596211985692,-1.5057183812598571,0.09305929398318494,0.32894076142978074,-0.015949191785796384,-1.7815233696066426,-0.4807050971530273,0.06605695177290508,-0.09949469747666943,-0.12769463103528156,-0.8636557041179473,0.1730932216945844,0.11989823952072967,0.3543879449769868,3.844530607020698,-0.24230752653304063,0.011554613903006978,-1.1380519309620947,0.09305929398318494,2.683879218936928,0.09305929398318494,0.03888935479482263,-0.1560737352527625,2.993609575094583,-0.21337800008247138,1.1626777008156755,-0.07147184402573621,0.11989823952072967,0.7657939331769242,0.09305929398318494,0.22565616698772623,-0.3599276825042347,2.186673620608435,0.11989823952072967,-0.5734566251984043,-0.4199119328370344,0.5528233698913807,0.5040506253802524,-0.21337800008247138,-0.07147184402573621,-0.07147184402573621,-0.09949469747666943,4.159435423734304,-0.4199119328370344,3.4053666094719595,0.25170495959874245,0.4794588708276966,0.19945282519176055,0.25170495959874245,0.03888935479482263,-0.1560737352527625,-0.09949469747666943,1.1626777008156755,0.09305929398318494,0.8797499948322487,-0.12769463103528156,0.429857390182749,1.1626777008156755,0.7426388328088186,-1.429818003064028,-0.9307313466100875,0.30334561141450944,-0.33023269302803204,3.204791775087714,-0.12769463103528156,0.22565616698772623,1.4674726459409988,1.1626777008156755,-0.24230752653304063,2.0009038654063014,-0.4199119328370344,-1.3182411457175676,0.45472828026538425
| 3,120
|
Protein localization
| 22
| 70
| 2.513609
| 0.01195
|
O60830,Q96B49,P21796,Q9UJS0,Q5JRX3,Q9NS69,P50402,Q15067,P09601,P51648,Q10713,A8MXV4,Q9Y512,Q8N4H5,O95169,O43808,Q9BY49,Q9NR77,Q15388,Q13505,Q3ZCQ8,O14925
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
3,264,16,411,160,35,290,300,296,47,55,181,459,72,444,332,467,80,346,88,240,113
|
181,939,113,703,762,615,675,1074,332,3070,3,1704,2870,618,2458,654,567,1179,2069,444,1077,766,1507,3034,296,2802,1079,1335,1274,16,1963,1773,1282,2809,2667,1461,596,290,47,1401,2922,504,55,462,1853,88,300,346,240,160,2768,72,2224,2567,1563,264,2990,467,1569,80,35,757,2241,2608,411,1027,728,459,2833,3105
|
1.4478182777817359,0.22565616698772623,2.1032619844886535,0.4048447144069418,0.3543879449769868,0.4794588708276966,0.429857390182749,0.1465756160978675,0.9021855262027676,-1.9889367176870343,5.022002691408248,-0.1560737352527625,-1.033222533253154,0.4794588708276966,-0.5734566251984043,0.45472828026538425,0.5285049852239486,0.09305929398318494,-0.33023269302803204,0.6959550565518066,0.1465756160978675,0.3543879449769868,-0.07147184402573621,-1.6219363686871284,1.012646583383761,-0.9307313466100875,0.1465756160978675,0.011554613903006978,0.03888935479482263,3.844530607020698,-0.2714249570573372,-0.18463413695639644,0.03888935479482263,-0.9307313466100875,-0.7323887974882097,-0.043624015597528217,0.5040506253802524,1.0344030160862734,3.0071390894611416,-0.015949191785796384,-1.1380519309620947,0.6249765506068089,2.9114638007546514,0.6724238788270614,-0.21337800008247138,2.4428044126478934,1.012646583383761,0.8797499948322487,1.1836886940989366,1.5835213327153648,-0.8636557041179473,2.683879218936928,-0.38981994606341763,-0.6363634842619023,-0.07147184402573621,1.120344057573255,-1.3551362796599622,0.6724238788270614,-0.07147184402573621,2.610061135094578,3.255890605195437,0.37968874363881105,-0.38981994606341763,-0.6681470252093221,0.7657939331769242,0.19945282519176055,0.4048447144069418,0.6959550565518066,-0.9307313466100875,-3.079808520036465
| 3,120
|
Mitophagy
| 6
| 12
| 2.513608
| 0.01195
|
Q9NS69,Q8N4H5,Q96B49,P21796,Q15388,O95140
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
35,72,264,16,346,429
|
2069,429,1077,2144,16,1970,433,346,72,264,2234,35
|
-0.33023269302803204,0.7193596211985692,0.1465756160978675,-0.3599276825042347,3.844530607020698,-0.2714249570573372,0.7193596211985692,0.8797499948322487,2.683879218936928,1.120344057573255,-0.38981994606341763,3.255890605195437
| 3,120
|
Glycerophospholipid metabolic process
| 14
| 54
| 2.502052
| 0.012348
|
Q5H8A4,Q9NPH0,Q96S52,P35790,Q8NCC3,Q9BVG9,Q9NZC3,Q969N2,Q10713,Q96N66,Q8TBX8,O00459,Q9NX62,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
248,6,302,42,11,144,283,385,55,153,219,339,224,30
|
2457,2755,339,2548,703,2502,1589,764,2782,1183,2074,1594,2203,42,1087,381,2934,2998,949,999,55,248,553,506,665,1550,638,1062,2170,11,537,219,30,1560,1010,640,385,153,1163,302,454,2489,1999,144,788,1213,6,1817,2776,224,3005,283,978,853
|
-0.5734566251984043,-0.8636557041179473,0.8797499948322487,-0.6363634842619023,0.4048447144069418,-0.6048009638951245,-0.09949469747666943,0.3543879449769868,-0.8970706209351134,0.09305929398318494,-0.33023269302803204,-0.09949469747666943,-0.38981994606341763,3.139985047591634,0.1465756160978675,0.8117366781974475,-1.1735319573878251,-1.3923270876756626,0.22565616698772623,0.19945282519176055,2.9114638007546514,1.1626777008156755,0.5528233698913807,0.6249765506068089,0.45472828026538425,-0.07147184402573621,0.4794588708276966,0.1730932216945844,-0.3599276825042347,4.159435423734304,0.5770071775774535,1.2667156015614143,3.4053666094719595,-0.07147184402573621,0.19945282519176055,0.4794588708276966,0.8117366781974475,1.640372274402174,0.11989823952072967,1.012646583383761,0.6959550565518066,-0.5734566251984043,-0.2714249570573372,1.77011455390589,0.3543879449769868,0.09305929398318494,4.588228239206742,-0.18463413695639644,-0.8636557041179473,1.2461096037129336,-1.429818003064028,1.0775884567819758,0.22565616698772623,0.30334561141450944
| 3,120
|
Lysosome
| 13
| 46
| 2.499158
| 0.012449
|
O14773,P11117,P20645,Q13510,P10619,Q14108,Q8NCC3,P17900,P15586,O15118,P50897,O75503,Q93050
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
66,97,165,71,200,105,11,268,238,112,48,115,279
|
1497,2385,66,112,675,892,115,1902,1124,898,2070,2618,591,1334,2836,1593,200,97,2996,1451,3088,238,476,268,165,3016,48,1715,276,2433,3074,1405,1408,71,105,744,11,2173,279,542,426,1572,2829,2543,1440,362
|
-0.07147184402573621,-0.5114114008305259,2.7850237629841788,2.1200791235371135,0.429857390182749,0.25170495959874245,2.086376421063753,-0.24230752653304063,0.11989823952072967,0.25170495959874245,-0.33023269302803204,-0.7001544799726708,0.5040506253802524,0.011554613903006978,-0.9646412623937256,-0.09949469747666943,1.3481584340693418,2.3167291137840786,-1.3923270876756626,-0.043624015597528217,-2.2504606922272252,1.1836886940989366,0.6487648093812882,1.0990194895203063,1.5451910091391072,-1.5057183812598571,2.993609575094583,-0.1560737352527625,1.0775884567819758,-0.5423276822514903,-1.9889367176870343,-0.015949191785796384,-0.015949191785796384,2.683879218936928,2.186673620608435,0.37968874363881105,4.159435423734304,-0.3599276825042347,1.0775884567819758,0.5770071775774535,0.7426388328088186,-0.07147184402573621,-0.9307313466100875,-0.6048009638951245,-0.015949191785796384,0.8571974386256007
| 3,120
|
Clumsiness
| 8
| 22
| 2.486893
| 0.012886
|
Q9NZJ7,O14773,Q13510,Q15067,O43819,Q9NR77,O75503,P35670
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
426,66,71,300,295,80,115,255
|
1225,66,1034,675,295,115,985,2808,2623,255,803,1244,433,71,300,1151,1355,1931,1365,80,426,2966
|
0.06605695177290508,2.7850237629841788,0.1730932216945844,0.429857390182749,1.012646583383761,2.086376421063753,0.19945282519176055,-0.9307313466100875,-0.7001544799726708,1.1415631395121968,0.32894076142978074,0.06605695177290508,0.7193596211985692,2.683879218936928,1.012646583383761,0.11989823952072967,0.011554613903006978,-0.24230752653304063,0.011554613903006978,2.610061135094578,0.7426388328088186,-1.2453206396228493
| 3,120
|
Proximal muscle weakness
| 17
| 63
| 2.482584
| 0.013043
|
P35670,P50402,Q13126,Q8TD16,Q13510,Q8NI60,P00846,P50336,Q9BQT8,P21912,P51530,Q99720,P07196,O95140,Q13501,O60313,P36551
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
255,290,133,326,71,228,9,170,101,477,297,20,119,429,433,340,127
|
1378,340,617,429,1588,9,1766,2956,985,119,1450,1272,1593,2985,1079,3088,1235,1646,477,2022,550,2808,1239,255,127,170,290,1840,804,297,1342,502,2764,2591,1194,133,2399,433,71,2162,2876,1200,2401,1793,1474,2403,687,1931,2225,228,2567,326,668,1064,1365,20,1427,101,1313,2113,849,1631,652
|
-0.015949191785796384,0.8797499948322487,0.4794588708276966,0.7193596211985692,-0.09949469747666943,4.375070750907427,-0.18463413695639644,-1.2453206396228493,0.19945282519176055,2.0181394542083764,-0.043624015597528217,0.03888935479482263,-0.09949469747666943,-1.3551362796599622,0.1465756160978675,-2.2504606922272252,0.06605695177290508,-0.12769463103528156,0.6487648093812882,-0.3007325721587227,0.5528233698913807,-0.9307313466100875,0.06605695177290508,1.1415631395121968,1.9662172504490403,1.5065101151687854,1.0344030160862734,-0.21337800008247138,0.32894076142978074,1.012646583383761,0.011554613903006978,0.6249765506068089,-0.8636557041179473,-0.6681470252093221,0.09305929398318494,1.9136403131944537,-0.5114114008305259,0.7193596211985692,2.683879218936928,-0.3599276825042347,-1.033222533253154,0.09305929398318494,-0.5114114008305259,-0.18463413695639644,-0.043624015597528217,-0.5114114008305259,0.429857390182749,-0.24230752653304063,-0.38981994606341763,1.2254037240919913,-0.6363634842619023,0.9467099920148521,0.45472828026538425,0.1730932216945844,0.011554613903006978,3.80054934068688,-0.015949191785796384,2.2845974095289043,0.03888935479482263,-0.33023269302803204,0.30334561141450944,-0.09949469747666943,0.4794588708276966
| 3,120
|
Pink1 prkn mediated mitophagy
| 6
| 9
| 2.482353
| 0.013052
|
Q9NS69,Q8N4H5,Q96B49,P21796,Q15388,O95140
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
35,72,264,16,346,429
|
2069,429,1077,16,433,346,72,264,35
|
-0.33023269302803204,0.7193596211985692,0.1465756160978675,3.844530607020698,0.7193596211985692,0.8797499948322487,2.683879218936928,1.120344057573255,3.255890605195437
| 3,120
|
Secondary alcohol metabolic process
| 14
| 40
| 2.468892
| 0.013553
|
Q14739,Q16850,P49748,P37268,P16435,Q15392,P04035,O15118,Q14534,P48449,Q8WTV0,P48735,P35610,O75845
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
195,65,344,68,327,230,267,112,172,85,30,275,122,310
|
112,2342,588,310,1179,1899,2616,267,1902,1510,402,327,2931,122,68,2391,85,275,344,2715,1843,1967,777,3074,1529,1664,600,2766,172,195,2269,1541,230,1982,686,65,30,2990,699,1173
|
2.1200791235371135,-0.4807050971530273,0.5040506253802524,0.9688011263013478,0.09305929398318494,-0.24230752653304063,-0.7001544799726708,1.0990194895203063,-0.24230752653304063,-0.07147184402573621,0.7657939331769242,0.9245051560552161,-1.1735319573878251,2.0009038654063014,2.770727945453716,-0.5114114008305259,2.489102096014749,1.0775884567819758,0.8797499948322487,-0.7975501035896743,-0.21337800008247138,-0.2714249570573372,0.3543879449769868,-1.9889367176870343,-0.07147184402573621,-0.12769463103528156,0.5040506253802524,-0.8636557041179473,1.487036333627781,1.388303199401113,-0.4199119328370344,-0.07147184402573621,1.2045970593385245,-0.2714249570573372,0.429857390182749,2.8134649963657146,3.4053666094719595,-1.3551362796599622,0.429857390182749,0.11989823952072967
| 3,120
|
Apical plasma membrane
| 8
| 48
| 2.435419
| 0.014875
|
P53985,P41440,Q8TAD4,Q99808,P08183,Q9Y4G8,P30825,P36551
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
104,204,208,242,22,125,126,127
|
1225,2576,940,2063,893,1271,1829,799,862,1332,22,767,1043,1769,2255,1392,1275,2712,447,1081,1706,1774,126,904,262,127,1460,204,1842,104,2318,626,2433,1469,1974,2360,2672,781,576,1095,208,1426,242,1683,1217,544,125,1175
|
0.06605695177290508,-0.6681470252093221,0.22565616698772623,-0.33023269302803204,0.25170495959874245,0.03888935479482263,-0.21337800008247138,0.32894076142978074,0.2776008882438347,0.011554613903006978,3.744867759885806,0.3543879449769868,0.1730932216945844,-0.18463413695639644,-0.4199119328370344,-0.015949191785796384,0.03888935479482263,-0.7975501035896743,0.6959550565518066,0.1465756160978675,-0.1560737352527625,-0.18463413695639644,1.9662172504490403,0.25170495959874245,1.120344057573255,1.9662172504490403,-0.043624015597528217,1.3279431624639007,-0.21337800008247138,2.186673620608435,-0.45020613666046194,0.4794588708276966,-0.5423276822514903,-0.043624015597528217,-0.2714249570573372,-0.4807050971530273,-0.7323887974882097,0.3543879449769868,0.5285049852239486,0.1465756160978675,1.3076315066448148,-0.015949191785796384,1.1836886940989366,-0.12769463103528156,0.09305929398318494,0.5770071775774535,2.0009038654063014,0.11989823952072967
| 3,120
|
Action tremor
| 9
| 55
| 2.432362
| 0.015001
|
Q5JRX3,O14773,P00846,Q8NC56,Q14108,P07814,Q9H6K4,Q9NR77,Q99720
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
160,66,9,138,105,14,111,80,20
|
2834,66,1034,2063,675,460,1178,1038,1271,429,1588,9,3014,2852,2139,14,2554,1187,1080,1963,2078,1776,1239,204,1596,1521,502,1844,1781,1531,105,1003,160,1151,2939,2165,638,1062,138,3092,3066,1104,20,1750,111,2493,1021,80,410,426,1172,1437,649,415,564
|
-0.9646412623937256,2.7850237629841788,0.1730932216945844,-0.33023269302803204,0.429857390182749,0.6724238788270614,0.09305929398318494,0.1730932216945844,0.03888935479482263,0.7193596211985692,-0.09949469747666943,4.375070750907427,-1.5057183812598571,-0.9988038179626447,-0.3599276825042347,3.9095867503469988,-0.6363634842619023,0.09305929398318494,0.1465756160978675,-0.2714249570573372,-0.33023269302803204,-0.18463413695639644,0.06605695177290508,1.3279431624639007,-0.09949469747666943,-0.07147184402573621,0.6249765506068089,-0.21337800008247138,-0.18463413695639644,-0.07147184402573621,2.186673620608435,0.19945282519176055,1.5835213327153648,0.11989823952072967,-1.1735319573878251,-0.3599276825042347,0.4794588708276966,0.1730932216945844,1.8782176443063971,-2.2954806321994075,-1.904873795283732,0.1465756160978675,3.80054934068688,-0.1560737352527625,2.1368283516262,-0.5734566251984043,0.19945282519176055,2.610061135094578,0.7657939331769242,0.7426388328088186,0.11989823952072967,-0.015949191785796384,0.4794588708276966,0.7657939331769242,0.5528233698913807
| 3,120
|
Steroid biosynthetic process
| 11
| 44
| 2.430623
| 0.015073
|
Q14739,Q16850,P37268,Q13510,Q15392,Q53GQ0,P04035,Q14534,P48449,P30536,O75845
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
195,65,68,71,230,205,267,172,85,25,310
|
588,310,1899,2616,267,862,1510,402,2620,327,1905,1963,2931,1282,25,68,2391,85,1843,1967,777,1664,600,71,2766,172,195,1541,230,1730,1148,1982,686,65,205,2107,1622,723,2111,887,1567,699,2337,3061
|
0.5040506253802524,0.9688011263013478,-0.24230752653304063,-0.7001544799726708,1.0990194895203063,0.2776008882438347,-0.07147184402573621,0.7657939331769242,-0.7001544799726708,0.9245051560552161,-0.24230752653304063,-0.2714249570573372,-1.1735319573878251,0.03888935479482263,3.607914396820148,2.770727945453716,-0.5114114008305259,2.489102096014749,-0.21337800008247138,-0.2714249570573372,0.3543879449769868,-0.12769463103528156,0.5040506253802524,2.683879218936928,-0.8636557041179473,1.487036333627781,1.388303199401113,-0.07147184402573621,1.2045970593385245,-0.1560737352527625,0.11989823952072967,-0.2714249570573372,0.429857390182749,2.8134649963657146,1.3279431624639007,-0.33023269302803204,-0.09949469747666943,0.4048447144069418,-0.33023269302803204,0.2776008882438347,-0.07147184402573621,0.429857390182749,-0.45020613666046194,-1.822282220676953
| 3,120
|
Metalloendopeptidase activity
| 8
| 15
| 2.418579
| 0.015581
|
O43847,Q5JRX3,Q9BYT8,Q9Y4W6,P42892,O75844,Q10713,P22695
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
220,160,425,564,102,13,55,274
|
220,2458,13,1274,274,102,1655,55,160,1743,2858,609,1426,425,564
|
1.2461096037129336,-0.5734566251984043,3.9629821531008274,0.03888935479482263,1.0775884567819758,2.26843717639146,-0.12769463103528156,2.9114638007546514,1.5835213327153648,-0.1560737352527625,-0.9988038179626447,0.5040506253802524,-0.015949191785796384,0.7426388328088186,0.5528233698913807
| 3,120
|
Vacuolar lumen
| 18
| 64
| 2.39235
| 0.016741
|
Q99536,Q9NZJ7,O14773,P11117,Q9UM22,Q9H7Z7,Q13510,P10619,Q14108,Q8IV08,P16278,P17900,P15586,P50897,P54802,Q8NHP8,Q13217,P38435
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
493,426,66,97,37,135,71,200,105,232,476,268,238,48,276,90,314,500
|
1227,2340,66,675,2616,678,1902,1124,898,2070,1389,827,2618,1230,591,1593,200,97,1644,1832,3088,238,476,268,499,1910,2203,500,3016,2084,1522,48,2151,1843,1715,1716,276,2764,1242,3074,1971,1915,2475,1665,314,71,105,1200,232,2856,90,1562,968,1810,493,610,1257,1875,135,1069,426,37,2543,2731
|
0.06605695177290508,-0.4807050971530273,2.7850237629841788,0.429857390182749,-0.7001544799726708,0.429857390182749,-0.24230752653304063,0.11989823952072967,0.25170495959874245,-0.33023269302803204,-0.015949191785796384,0.30334561141450944,-0.7001544799726708,0.06605695177290508,0.5040506253802524,-0.09949469747666943,1.3481584340693418,2.3167291137840786,-0.12769463103528156,-0.21337800008247138,-2.2504606922272252,1.1836886940989366,0.6487648093812882,1.0990194895203063,0.6249765506068089,-0.24230752653304063,-0.38981994606341763,0.6249765506068089,-1.5057183812598571,-0.33023269302803204,-0.07147184402573621,2.993609575094583,-0.3599276825042347,-0.21337800008247138,-0.1560737352527625,-0.1560737352527625,1.0775884567819758,-0.8636557041179473,0.06605695177290508,-1.9889367176870343,-0.2714249570573372,-0.24230752653304063,-0.5734566251984043,-0.12769463103528156,0.9688011263013478,2.683879218936928,2.186673620608435,0.09305929398318494,1.2045970593385245,-0.9988038179626447,2.427254953547532,-0.07147184402573621,0.22565616698772623,-0.18463413695639644,0.6487648093812882,0.5040506253802524,0.06605695177290508,-0.21337800008247138,1.8959665059951594,0.1730932216945844,0.7426388328088186,3.204791775087714,-0.6048009638951245,-0.7975501035896743
| 3,120
|
Cholesterol biosynthesis pathway
| 6
| 14
| 2.370863
| 0.017747
|
Q16850,P37268,P04035,Q14534,P48449,O75845
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
65,68,267,172,85,310
|
310,267,402,68,85,1967,1664,2766,172,1541,1982,686,65,699
|
0.9688011263013478,1.0990194895203063,0.7657939331769242,2.770727945453716,2.489102096014749,-0.2714249570573372,-0.12769463103528156,-0.8636557041179473,1.487036333627781,-0.07147184402573621,-0.2714249570573372,0.429857390182749,2.8134649963657146,0.429857390182749
| 3,120
|
Glycoprotein biosynthetic process
| 10
| 51
| 2.368918
| 0.01784
|
Q96JB2,Q99805,O60476,O43505,Q96L58,O15118,Q7LGA3,Q8NCH0,Q9H6U8,P35610
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,131,192,141,175,112,17,117,188,122
|
2709,112,2249,141,192,443,858,1639,2502,617,2581,765,1643,3089,2080,122,988,1649,2089,2397,2093,1469,1194,2526,717,214,838,1246,1144,1004,720,17,2701,666,117,1100,370,96,175,1164,131,319,1366,1066,2117,694,188,849,1882,1261,2572
|
-0.7975501035896743,2.1200791235371135,-0.4199119328370344,1.8424923729445961,1.388303199401113,0.6959550565518066,0.2776008882438347,-0.12769463103528156,-0.6048009638951245,0.4794588708276966,-0.6681470252093221,0.3543879449769868,-0.12769463103528156,-2.2504606922272252,-0.33023269302803204,2.0009038654063014,0.19945282519176055,-0.12769463103528156,-0.33023269302803204,-0.5114114008305259,-0.33023269302803204,-0.043624015597528217,0.09305929398318494,-0.6048009638951245,0.4048447144069418,1.287222609209894,0.30334561141450944,0.06605695177290508,0.11989823952072967,0.19945282519176055,0.4048447144069418,3.811591163952668,-0.764852983812969,0.45472828026538425,2.069421914151396,0.1465756160978675,0.8345267182780652,2.3644615317552153,1.487036333627781,0.11989823952072967,1.9312396535039034,0.9688011263013478,0.011554613903006978,0.1730932216945844,-0.33023269302803204,0.429857390182749,1.4280724450354945,0.30334561141450944,-0.21337800008247138,0.06605695177290508,-0.6363634842619023
| 3,120
|
Peptide binding
| 15
| 64
| 2.361358
| 0.018208
|
P24390,O14773,Q9BYT8,Q9UIQ6,O00264,Q9H7Z7,Q9NZ08,P42892,Q15392,P10321,P55786,Q15388,O00629,Q8WTV0,O15212
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
33,66,425,132,191,135,100,102,230,333,54,346,155,30,363
|
191,1697,2297,155,66,363,2710,2069,1901,861,1769,1334,2836,333,1274,2738,2464,33,2944,1964,3090,2840,903,1396,2026,1461,102,3009,1596,1400,1520,1049,2785,1780,54,1659,2588,599,2716,1723,1666,1198,2562,2163,346,230,1156,1157,30,966,1481,969,1998,2333,425,1017,135,2053,2055,100,1174,440,132,2867
|
1.388303199401113,-0.1560737352527625,-0.45020613666046194,1.621506944075928,2.7850237629841788,0.8345267182780652,-0.7975501035896743,-0.33023269302803204,-0.24230752653304063,0.2776008882438347,-0.18463413695639644,0.011554613903006978,-0.9646412623937256,0.9021855262027676,0.03888935479482263,-0.8304832815585822,-0.5734566251984043,3.281196558065222,-1.2092868657343552,-0.2714249570573372,-2.2954806321994075,-0.9646412623937256,0.25170495959874245,-0.015949191785796384,-0.3007325721587227,-0.043624015597528217,2.26843717639146,-1.4676135569727793,-0.09949469747666943,-0.015949191785796384,-0.07147184402573621,0.1730932216945844,-0.8970706209351134,-0.18463413695639644,2.9114638007546514,-0.12769463103528156,-0.6681470252093221,0.5040506253802524,-0.7975501035896743,-0.1560737352527625,-0.12769463103528156,0.09305929398318494,-0.6363634842619023,-0.3599276825042347,0.8797499948322487,1.2045970593385245,0.11989823952072967,0.11989823952072967,3.4053666094719595,0.22565616698772623,-0.043624015597528217,0.22565616698772623,-0.2714249570573372,-0.45020613666046194,0.7426388328088186,0.19945282519176055,1.8959665059951594,-0.3007325721587227,-0.3007325721587227,2.3167291137840786,0.11989823952072967,0.7193596211985692,1.9312396535039034,-0.9988038179626447
| 3,120
|
Intrinsic component of endoplasmic reticulum membrane
| 20
| 53
| 2.353946
| 0.018575
|
O75844,Q9NPA0,Q96S52,Q9UM00,Q8TCT9,P10321,Q9NQC3,O75298,Q96A33,Q9Y282,Q86XL3,Q5H8A4,P51572,Q8TB61,O95470,Q8N4V1,O76024,Q15629,Q969N2,Q12981
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
13,409,302,441,325,333,212,81,463,87,95,248,354,369,107,368,254,121,385,382
|
822,3022,2994,81,13,254,107,1901,861,333,2944,2024,2512,354,1402,2588,382,2637,920,1296,121,2563,248,921,664,2404,95,666,368,1556,369,325,640,385,1422,463,302,1425,1626,1165,1315,2707,409,212,2913,511,2570,2928,699,441,87,729,1224
|
0.30334561141450944,-1.5441372114598413,-1.3923270876756626,2.5801554718278767,3.9629821531008274,1.1415631395121968,2.1535101765609372,-0.24230752653304063,0.2776008882438347,0.9021855262027676,-1.2092868657343552,-0.3007325721587227,-0.6048009638951245,0.8571974386256007,-0.015949191785796384,-0.6681470252093221,0.8117366781974475,-0.7001544799726708,0.25170495959874245,0.03888935479482263,2.0181394542083764,-0.6363634842619023,1.1626777008156755,0.25170495959874245,0.45472828026538425,-0.5114114008305259,2.3644615317552153,0.45472828026538425,0.8345267182780652,-0.07147184402573621,0.8345267182780652,0.9467099920148521,0.4794588708276966,0.8117366781974475,-0.015949191785796384,0.6724238788270614,1.012646583383761,-0.015949191785796384,-0.09949469747666943,0.11989823952072967,0.03888935479482263,-0.764852983812969,0.7657939331769242,1.3076315066448148,-1.1028428854778956,0.6249765506068089,-0.6363634842619023,-1.1380519309620947,0.429857390182749,0.7193596211985692,2.473727575246269,0.4048447144069418,0.09305929398318494
| 3,120
|
Steroid biosynthesis
| 6
| 11
| 2.348673
| 0.01884
|
Q16850,P37268,Q15392,Q14534,P48449,P35610
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
65,68,230,172,85,122
|
310,122,68,3016,85,172,230,1982,686,65,699
|
0.9688011263013478,2.0009038654063014,2.770727945453716,-1.5057183812598571,2.489102096014749,1.487036333627781,1.2045970593385245,-0.2714249570573372,0.429857390182749,2.8134649963657146,0.429857390182749
| 3,120
|
Visual loss
| 6
| 51
| 2.343903
| 0.019083
|
O14773,P00846,P07814,P50897,P48449,Q10713
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,9,14,48,85,55
|
1891,1578,2248,730,66,1698,340,1178,2458,115,1446,429,225,2251,9,1901,3014,2956,861,14,1831,2462,770,2080,1397,1087,85,48,1401,1523,2392,502,1717,1531,55,2398,2357,2267,2790,1735,638,2173,1063,1064,2279,579,524,2111,2493,1220,426
|
-0.24230752653304063,-0.09949469747666943,-0.4199119328370344,0.37968874363881105,2.7850237629841788,-0.1560737352527625,0.8797499948322487,0.09305929398318494,-0.5734566251984043,2.086376421063753,-0.043624015597528217,0.7193596211985692,1.2254037240919913,-0.4199119328370344,4.375070750907427,-0.24230752653304063,-1.5057183812598571,-1.2453206396228493,0.2776008882438347,3.9095867503469988,-0.21337800008247138,-0.5734566251984043,0.3543879449769868,-0.33023269302803204,-0.015949191785796384,0.1465756160978675,2.489102096014749,2.993609575094583,-0.015949191785796384,-0.07147184402573621,-0.5114114008305259,0.6249765506068089,-0.1560737352527625,-0.07147184402573621,2.9114638007546514,-0.5114114008305259,-0.4807050971530273,-0.4199119328370344,-0.8970706209351134,-0.1560737352527625,0.4794588708276966,-0.3599276825042347,0.1730932216945844,0.1730932216945844,-0.4199119328370344,0.5285049852239486,0.6010577855594291,-0.33023269302803204,-0.5734566251984043,0.09305929398318494,0.7426388328088186
| 3,120
|
Limb ataxia
| 7
| 27
| 2.340601
| 0.019253
|
O14773,Q14108,P41440,Q9NR77,O75298,P07196,Q10713
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,105,204,80,81,119,55
|
2834,66,2063,81,1902,2852,119,2617,3002,1278,2808,1776,204,502,55,433,105,232,1931,1104,2113,1751,80,410,1172,1437,564
|
-0.9646412623937256,2.7850237629841788,-0.33023269302803204,2.5801554718278767,-0.24230752653304063,-0.9988038179626447,2.0181394542083764,-0.7001544799726708,-1.429818003064028,0.03888935479482263,-0.9307313466100875,-0.18463413695639644,1.3279431624639007,0.6249765506068089,2.9114638007546514,0.7193596211985692,2.186673620608435,1.2045970593385245,-0.24230752653304063,0.1465756160978675,-0.33023269302803204,-0.1560737352527625,2.610061135094578,0.7657939331769242,0.11989823952072967,-0.015949191785796384,0.5528233698913807
| 3,120
|
Parkinsons disease
| 14
| 57
| 2.337557
| 0.01941
|
P24539,P00403,Q9UDW1,P45880,O14548,P00846,P14406,Q9Y277,P21796,O96000,O14949,P14927,P22695,P13073
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
129,225,36,70,199,9,41,78,16,178,19,147,274,57
|
3021,2062,199,19,1955,3104,2780,2930,1178,2551,1385,568,529,444,1587,2503,178,225,9,3014,1229,766,1507,864,2711,1079,1335,57,41,147,1771,2584,288,16,477,2022,274,129,1773,2147,2808,2309,711,70,2814,2032,3040,3029,3017,911,1723,745,958,3066,36,78,565
|
-1.5441372114598413,-0.33023269302803204,1.3481584340693418,3.80054934068688,-0.2714249570573372,-2.9227381542310105,-0.8970706209351134,-1.1735319573878251,0.09305929398318494,-0.6363634842619023,-0.015949191785796384,0.5285049852239486,0.5770071775774535,0.6959550565518066,-0.09949469747666943,-0.6048009638951245,1.4674726459409988,1.2254037240919913,4.375070750907427,-1.5057183812598571,0.06605695177290508,0.3543879449769868,-0.07147184402573621,0.2776008882438347,-0.7975501035896743,0.1465756160978675,0.011554613903006978,2.897608649302585,3.139985047591634,1.7150000315769534,-0.18463413695639644,-0.6681470252093221,1.0344030160862734,3.844530607020698,0.6487648093812882,-0.3007325721587227,1.0775884567819758,1.9312396535039034,-0.18463413695639644,-0.3599276825042347,-0.9307313466100875,-0.45020613666046194,0.4048447144069418,2.683879218936928,-0.9307313466100875,-0.3007325721587227,-1.6613267134213334,-1.582874889859472,-1.5057183812598571,0.25170495959874245,-0.1560737352527625,0.37968874363881105,0.22565616698772623,-1.904873795283732,3.2176279524756564,2.6397490931199465,0.5528233698913807
| 3,120
|
Organic hydroxy compound biosynthetic process
| 14
| 52
| 2.336124
| 0.019485
|
Q14739,Q16850,P37268,Q13510,P16435,P00374,P05091,Q15392,P04035,Q14534,P48449,Q9Y4G8,P14324,O75845
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
195,65,68,71,327,44,76,230,267,172,85,125,402,310
|
2457,1760,1378,587,2129,588,310,1899,44,2616,267,1902,76,863,1510,402,327,1904,1905,1963,1282,419,68,2391,85,1843,1967,777,2036,1664,1469,600,71,2766,172,195,1541,230,1982,686,2271,65,1622,1482,723,3066,2111,543,699,3061,125,2983
|
-0.5734566251984043,-0.18463413695639644,-0.015949191785796384,0.5040506253802524,-0.3599276825042347,0.5040506253802524,0.9688011263013478,-0.24230752653304063,3.087373369880343,-0.7001544799726708,1.0990194895203063,-0.24230752653304063,2.6397490931199465,0.2776008882438347,-0.07147184402573621,0.7657939331769242,0.9245051560552161,-0.24230752653304063,-0.24230752653304063,-0.2714249570573372,0.03888935479482263,0.7426388328088186,2.770727945453716,-0.5114114008305259,2.489102096014749,-0.21337800008247138,-0.2714249570573372,0.3543879449769868,-0.3007325721587227,-0.12769463103528156,-0.043624015597528217,0.5040506253802524,2.683879218936928,-0.8636557041179473,1.487036333627781,1.388303199401113,-0.07147184402573621,1.2045970593385245,-0.2714249570573372,0.429857390182749,-0.4199119328370344,2.8134649963657146,-0.09949469747666943,-0.043624015597528217,0.4048447144069418,-1.904873795283732,-0.33023269302803204,0.5770071775774535,0.429857390182749,-1.822282220676953,2.0009038654063014,-1.3182411457175676
| 3,120
|
Lipase activity
| 7
| 19
| 2.326645
| 0.019984
|
Q8N2A8,Q8NCG7,Q8NCC3,Q8IV08,Q9NZC3,Q8NHP8,Q9H6V9
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
137,301,11,232,283,90,59
|
2014,2302,296,1594,2203,2512,3016,232,638,137,1062,2170,11,301,90,59,3005,283,1952
|
-0.3007325721587227,-0.45020613666046194,1.012646583383761,-0.09949469747666943,-0.38981994606341763,-0.6048009638951245,-1.5057183812598571,1.2045970593385245,0.4794588708276966,1.8782176443063971,0.1730932216945844,-0.3599276825042347,4.159435423734304,1.012646583383761,2.427254953547532,2.8837057870744482,-1.429818003064028,1.0775884567819758,-0.24230752653304063
| 3,120
|
Sphingolipid metabolic process
| 11
| 27
| 2.324316
| 0.020109
|
Q9NZJ7,Q06136,Q99805,Q53H12,Q13510,Q8NCC3,P16278,O95470,P17900,P50897,Q9NZD2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
426,130,131,450,71,11,476,107,268,48,252
|
2885,587,2129,1955,107,1902,898,2070,2618,476,268,1905,1514,48,1665,130,71,450,664,11,131,3005,2913,252,426,511,2241
|
-1.0679010003564908,0.5040506253802524,-0.3599276825042347,-0.2714249570573372,2.1535101765609372,-0.24230752653304063,0.25170495959874245,-0.33023269302803204,-0.7001544799726708,0.6487648093812882,1.0990194895203063,-0.24230752653304063,-0.07147184402573621,2.993609575094583,-0.12769463103528156,1.9312396535039034,2.683879218936928,0.6959550565518066,0.45472828026538425,4.159435423734304,1.9312396535039034,-1.429818003064028,-1.1028428854778956,1.1626777008156755,0.7426388328088186,0.6249765506068089,-0.38981994606341763
| 3,120
|
Protease
| 22
| 80
| 2.321975
| 0.020234
|
Q7Z2K6,P28074,Q9UIQ6,P42785,O75844,Q9HB40,Q5JRX3,Q9BYT8,Q4J6C6,P28072,Q9H3G5,P55786,O14773,Q8TCT9,P10619,Q16740,P09960,Q99436,O43847,Q9NZ08,P42892,Q96K76
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
257,378,132,7,13,32,160,425,39,418,43,54,66,325,200,201,213,465,220,100,102,371
|
1442,1116,66,1955,220,2458,13,1122,860,945,2617,213,200,2803,1274,2074,418,378,2585,2622,1458,7,102,1913,907,1653,1779,1655,1780,1715,2262,54,1135,2746,2440,2697,2594,201,39,160,2529,3057,257,1863,1551,325,878,640,1743,1563,1994,3080,2858,2679,2598,371,1162,492,609,465,3066,1426,425,646,43,2898,2239,1106,32,1021,1940,2798,1434,100,132,2059,2883,1758,564,2546
|
-0.043624015597528217,0.11989823952072967,2.7850237629841788,-0.2714249570573372,1.2461096037129336,-0.5734566251984043,3.9629821531008274,0.11989823952072967,0.2776008882438347,0.22565616698772623,-0.7001544799726708,1.287222609209894,1.3481584340693418,-0.9307313466100875,0.03888935479482263,-0.33023269302803204,0.7426388328088186,0.8117366781974475,-0.6681470252093221,-0.7001544799726708,-0.043624015597528217,4.524607180078603,2.26843717639146,-0.24230752653304063,0.25170495959874245,-0.12769463103528156,-0.18463413695639644,-0.12769463103528156,-0.18463413695639644,-0.1560737352527625,-0.4199119328370344,2.9114638007546514,0.11989823952072967,-0.8304832815585822,-0.5423276822514903,-0.764852983812969,-0.6681470252093221,1.3481584340693418,3.1530306783954622,1.5835213327153648,-0.6048009638951245,-1.7815233696066426,1.1415631395121968,-0.21337800008247138,-0.07147184402573621,0.9467099920148521,0.2776008882438347,0.4794588708276966,-0.1560737352527625,-0.07147184402573621,-0.2714249570573372,-2.1178987452790463,-0.9988038179626447,-0.7323887974882097,-0.6681470252093221,0.8345267182780652,0.11989823952072967,0.6487648093812882,0.5040506253802524,0.6724238788270614,-1.904873795283732,-0.015949191785796384,0.7426388328088186,0.4794588708276966,3.139985047591634,-1.0679010003564908,-0.38981994606341763,0.1465756160978675,3.3188565054042503,0.19945282519176055,-0.24230752653304063,-0.8970706209351134,-0.015949191785796384,2.3167291137840786,1.9312396535039034,-0.3007325721587227,-1.033222533253154,-0.1560737352527625,0.5528233698913807,-0.6048009638951245
| 3,120
|
Abnormal visual electrophysiology
| 16
| 52
| 2.31295
| 0.020725
|
Q9NZJ7,O14773,Q53H12,Q9H936,P00846,Q15067,Q86YH6,Q15555,Q9GZY8,P50897,O43924,Q9H0F7,O75503,O95140,P54098,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
426,66,450,496,9,300,328,393,207,48,79,352,115,429,502,340
|
66,1698,2298,1036,675,2342,79,3070,340,115,1581,2800,429,9,1079,499,1397,1189,1087,2715,48,1401,502,2519,1717,573,1975,1246,1981,300,393,782,450,1615,2368,328,638,1556,1063,964,1362,815,2000,207,352,1167,496,1217,2980,2240,426,2607
|
2.7850237629841788,-0.1560737352527625,-0.45020613666046194,0.1730932216945844,0.429857390182749,-0.4807050971530273,2.610061135094578,-1.9889367176870343,0.8797499948322487,2.086376421063753,-0.09949469747666943,-0.9307313466100875,0.7193596211985692,4.375070750907427,0.1465756160978675,0.6249765506068089,-0.015949191785796384,0.09305929398318494,0.1465756160978675,-0.7975501035896743,2.993609575094583,-0.015949191785796384,0.6249765506068089,-0.6048009638951245,-0.1560737352527625,0.5285049852239486,-0.2714249570573372,0.06605695177290508,-0.2714249570573372,1.012646583383761,0.7888261461963076,0.3543879449769868,0.6959550565518066,-0.09949469747666943,-0.4807050971530273,0.9245051560552161,0.4794588708276966,-0.07147184402573621,0.1730932216945844,0.22565616698772623,0.011554613903006978,0.32894076142978074,-0.2714249570573372,1.3279431624639007,0.8797499948322487,0.11989823952072967,0.6487648093812882,0.09305929398318494,-1.3182411457175676,-0.38981994606341763,0.7426388328088186,-0.6681470252093221
| 3,120
|
Alcohol biosynthetic process
| 15
| 37
| 2.309753
| 0.020902
|
Q14739,Q16850,P37268,Q13510,P35270,P16435,P00374,Q15392,P04035,Q9NPH2,Q12770,P48449,O15269,P14324,O75845
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
195,65,68,71,419,327,44,230,267,543,600,85,587,402,310
|
2457,587,2129,588,310,1899,44,2616,267,1902,863,1510,402,327,1904,419,68,2391,85,1843,1967,777,2036,1664,600,71,2766,195,1541,230,1982,686,2271,65,3066,543,699
|
-0.5734566251984043,0.5040506253802524,-0.3599276825042347,0.5040506253802524,0.9688011263013478,-0.24230752653304063,3.087373369880343,-0.7001544799726708,1.0990194895203063,-0.24230752653304063,0.2776008882438347,-0.07147184402573621,0.7657939331769242,0.9245051560552161,-0.24230752653304063,0.7426388328088186,2.770727945453716,-0.5114114008305259,2.489102096014749,-0.21337800008247138,-0.2714249570573372,0.3543879449769868,-0.3007325721587227,-0.12769463103528156,0.5040506253802524,2.683879218936928,-0.8636557041179473,1.388303199401113,-0.07147184402573621,1.2045970593385245,-0.2714249570573372,0.429857390182749,-0.4199119328370344,2.8134649963657146,-1.904873795283732,0.5770071775774535,0.429857390182749
| 3,120
|
Ferroptosis
| 6
| 24
| 2.305743
| 0.021125
|
P37268,P45880,Q9Y277,P09601,P04035,Q9NZ45
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
68,70,78,296,267,86
|
1893,1589,825,678,267,2685,2505,767,296,327,1131,68,70,1464,1596,2672,2819,2638,1415,1796,1683,86,934,78
|
-0.24230752653304063,-0.09949469747666943,0.30334561141450944,0.429857390182749,1.0990194895203063,-0.764852983812969,-0.6048009638951245,0.3543879449769868,1.012646583383761,0.9245051560552161,0.11989823952072967,2.770727945453716,2.683879218936928,-0.043624015597528217,-0.09949469747666943,-0.7323887974882097,-0.9307313466100875,-0.7001544799726708,-0.015949191785796384,-0.18463413695639644,-0.12769463103528156,2.489102096014749,0.25170495959874245,2.6397490931199465
| 3,120
|
Amino acid transport
| 11
| 20
| 2.3048
| 0.021178
|
Q9H936,Q9H9B4,Q8TDW0,P55011,O75746,O75915,P08195,Q9UJS0,P21359,P30825,Q6P4A7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
496,526,423,626,567,621,767,411,770,126,719
|
940,1378,1640,567,621,1768,767,770,126,626,1296,1981,1415,719,423,882,1683,496,526,411
|
0.22565616698772623,-0.015949191785796384,-0.12769463103528156,0.5285049852239486,0.4794588708276966,-0.18463413695639644,0.3543879449769868,0.3543879449769868,1.9662172504490403,0.4794588708276966,0.03888935479482263,-0.2714249570573372,-0.015949191785796384,0.4048447144069418,0.7426388328088186,0.2776008882438347,-0.12769463103528156,0.6487648093812882,0.6010577855594291,0.7657939331769242
| 3,120
|
golgi
| 11
| 66
| 2.303063
| 0.021275
|
Q9Y487,P36543,Q9BXB4,Q9UI14,Q8IXU6,Q8TAD4,O15127,P53367,Q15907,Q5VW38,Q8NBN3
|
Localization
|
OpenCell Localization
|
opencell_localization
|
362,262,303,139,49,208,118,245,61,62,31
|
1499,702,2548,940,2128,1117,118,1035,943,1271,2459,1588,1334,2836,2256,1046,1905,2259,262,2714,625,245,1524,1466,1657,2691,1291,1660,714,2091,1405,999,2526,1853,1146,956,2361,744,61,62,2821,49,1554,923,31,208,2406,927,1479,523,303,373,1167,1876,756,1817,2241,544,727,139,441,1031,938,1222,362,1577
|
-0.07147184402573621,0.4048447144069418,-0.6363634842619023,0.22565616698772623,-0.3599276825042347,0.11989823952072967,2.035303964448664,0.1730932216945844,0.22565616698772623,0.03888935479482263,-0.5734566251984043,-0.09949469747666943,0.011554613903006978,-0.9646412623937256,-0.4199119328370344,0.1730932216945844,-0.24230752653304063,-0.4199119328370344,1.120344057573255,-0.7975501035896743,0.4794588708276966,1.1626777008156755,-0.07147184402573621,-0.043624015597528217,-0.12769463103528156,-0.764852983812969,0.03888935479482263,-0.12769463103528156,0.4048447144069418,-0.33023269302803204,-0.015949191785796384,0.19945282519176055,-0.6048009638951245,-0.21337800008247138,0.11989823952072967,0.22565616698772623,-0.4807050971530273,0.37968874363881105,2.8557557026843536,2.8557557026843536,-0.9307313466100875,2.993609575094583,-0.07147184402573621,0.25170495959874245,3.3188565054042503,1.3076315066448148,-0.5114114008305259,0.25170495959874245,-0.043624015597528217,0.6010577855594291,1.012646583383761,0.8345267182780652,0.11989823952072967,-0.21337800008247138,0.37968874363881105,-0.18463413695639644,-0.38981994606341763,0.5770071775774535,0.4048447144069418,1.8782176443063971,0.7193596211985692,0.19945282519176055,0.25170495959874245,0.09305929398318494,0.8571974386256007,-0.07147184402573621
| 3,120
|
Oxidase
| 9
| 21
| 2.299677
| 0.021467
|
O15260,P20674,O43169,O14548,P14406,Q15067,O43819,O75845,P36551
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
321,288,38,199,41,300,295,310,127
|
199,762,321,38,295,310,1583,2711,2985,2837,41,1771,288,2933,127,344,300,686,1733,2532,1168
|
1.3481584340693418,0.3543879449769868,0.9467099920148521,3.1919142087444814,1.012646583383761,0.9688011263013478,-0.09949469747666943,-0.7975501035896743,-1.3551362796599622,-0.9646412623937256,3.139985047591634,-0.18463413695639644,1.0344030160862734,-1.1735319573878251,1.9662172504490403,0.8797499948322487,1.012646583383761,0.429857390182749,-0.1560737352527625,-0.6048009638951245,0.11989823952072967
| 3,120
|
Dicarboxylic acid transmembrane transporter activity
| 6
| 8
| 2.299641
| 0.021469
|
Q9H936,Q9BQT8,P41440,Q9UJS0,Q02978,Q9UBX3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
496,101,204,411,432,157
|
567,204,432,1415,101,496,157,411
|
0.5285049852239486,1.3279431624639007,0.7193596211985692,-0.015949191785796384,2.2845974095289043,0.6487648093812882,1.621506944075928,0.7657939331769242
| 3,120
|
Glycerophospholipid biosynthetic process
| 11
| 38
| 2.296717
| 0.021635
|
Q5H8A4,Q9NPH0,Q96S52,P35790,Q9BVG9,Q969N2,Q10713,Q96N66,Q8TBX8,O00459,Q9NX62
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
248,6,302,42,144,385,55,153,219,339,224
|
2755,339,2548,703,2502,1589,764,2782,1183,2074,42,381,2998,999,55,248,553,506,665,1550,537,219,1560,1010,640,385,153,1163,302,2489,1999,144,788,6,1817,2776,224,978
|
-0.8636557041179473,0.8797499948322487,-0.6363634842619023,0.4048447144069418,-0.6048009638951245,-0.09949469747666943,0.3543879449769868,-0.8970706209351134,0.09305929398318494,-0.33023269302803204,3.139985047591634,0.8117366781974475,-1.3923270876756626,0.19945282519176055,2.9114638007546514,1.1626777008156755,0.5528233698913807,0.6249765506068089,0.45472828026538425,-0.07147184402573621,0.5770071775774535,1.2667156015614143,-0.07147184402573621,0.19945282519176055,0.4794588708276966,0.8117366781974475,1.640372274402174,0.11989823952072967,1.012646583383761,-0.5734566251984043,-0.2714249570573372,1.77011455390589,0.3543879449769868,4.588228239206742,-0.18463413695639644,-0.8636557041179473,1.2461096037129336,0.22565616698772623
| 3,120
|
Electron transport chain oxphos system in mitochondria
| 14
| 54
| 2.296535
| 0.021645
|
P24539,P00403,Q7KZN9,Q9UDW1,Q9Y6N1,O14548,P00846,P14406,O96000,O14949,P14927,O75964,P22695,P13073
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
129,225,185,36,198,199,9,41,178,19,147,52,274,57
|
3021,2062,199,19,3104,2780,2930,1178,2551,1385,1583,568,52,529,444,1587,2503,178,225,9,3014,1229,766,864,2711,1079,1335,57,41,147,1771,2584,288,477,274,129,1773,2147,2808,2309,711,2814,2032,3040,3029,2632,1845,745,958,185,36,936,565,198
|
-1.5441372114598413,-0.33023269302803204,1.3481584340693418,3.80054934068688,-2.9227381542310105,-0.8970706209351134,-1.1735319573878251,0.09305929398318494,-0.6363634842619023,-0.015949191785796384,-0.09949469747666943,0.5285049852239486,2.925271544766199,0.5770071775774535,0.6959550565518066,-0.09949469747666943,-0.6048009638951245,1.4674726459409988,1.2254037240919913,4.375070750907427,-1.5057183812598571,0.06605695177290508,0.3543879449769868,0.2776008882438347,-0.7975501035896743,0.1465756160978675,0.011554613903006978,2.897608649302585,3.139985047591634,1.7150000315769534,-0.18463413695639644,-0.6681470252093221,1.0344030160862734,0.6487648093812882,1.0775884567819758,1.9312396535039034,-0.18463413695639644,-0.3599276825042347,-0.9307313466100875,-0.45020613666046194,0.4048447144069418,-0.9307313466100875,-0.3007325721587227,-1.6613267134213334,-1.582874889859472,-0.7001544799726708,-0.21337800008247138,0.37968874363881105,0.22565616698772623,1.4280724450354945,3.2176279524756564,0.25170495959874245,0.5528233698913807,1.3682781678569051
| 3,120
|
Biological oxidations
| 11
| 43
| 2.290781
| 0.021976
|
Q16850,O43169,P07099,P16435,Q86WA6,P05091,Q8TB61,Q9NUJ1,P21964,P30837,Q9NX62
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
65,38,10,327,173,76,369,282,146,60,224
|
2248,548,38,2299,2869,2578,1639,2661,2782,2616,76,10,1769,3008,1903,1392,327,2738,146,2931,2932,1964,60,802,1464,1596,1663,2322,65,1350,1058,173,369,1307,1995,1162,372,1998,1683,282,224,2290,728
|
-0.4199119328370344,0.5528233698913807,3.1919142087444814,-0.45020613666046194,-1.033222533253154,-0.6681470252093221,-0.12769463103528156,-0.7323887974882097,-0.8970706209351134,-0.7001544799726708,2.6397490931199465,4.209515969875745,-0.18463413695639644,-1.4676135569727793,-0.24230752653304063,-0.015949191785796384,0.9245051560552161,-0.8304832815585822,1.733451983355156,-1.1735319573878251,-1.1735319573878251,-0.2714249570573372,2.8697549078890536,0.32894076142978074,-0.043624015597528217,-0.09949469747666943,-0.12769463103528156,-0.45020613666046194,2.8134649963657146,0.011554613903006978,0.1730932216945844,1.487036333627781,0.8345267182780652,0.03888935479482263,-0.2714249570573372,0.11989823952072967,0.8345267182780652,-0.2714249570573372,-0.12769463103528156,1.0775884567819758,1.2461096037129336,-0.4199119328370344,0.4048447144069418
| 3,120
|
Regulation of hormone levels
| 13
| 60
| 2.2714
| 0.023123
|
Q9HB40,P42892,Q16836,P53985,P16435,O95470,O75844,Q53GQ0,Q8TAD4,Q8N5M9,P30536,P50416,Q15907
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,102,347,104,327,107,13,205,208,338,25,403,61
|
2902,2576,1265,1893,2012,1271,13,107,569,1590,799,862,1043,1274,2620,327,1186,1905,25,2841,1087,102,2626,403,1401,1048,104,2520,2091,912,2525,2718,1409,659,2160,2672,1148,61,2271,347,205,534,1301,338,1992,2107,436,208,1063,2648,2680,751,3066,2111,32,1020,699,1437,980,1757
|
-1.1028428854778956,-0.6681470252093221,0.03888935479482263,-0.24230752653304063,-0.3007325721587227,0.03888935479482263,3.9629821531008274,2.1535101765609372,0.5285049852239486,-0.09949469747666943,0.32894076142978074,0.2776008882438347,0.1730932216945844,0.03888935479482263,-0.7001544799726708,0.9245051560552161,0.09305929398318494,-0.24230752653304063,3.607914396820148,-0.9646412623937256,0.1465756160978675,2.26843717639146,-0.7001544799726708,0.7657939331769242,-0.015949191785796384,0.1730932216945844,2.186673620608435,-0.6048009638951245,-0.33023269302803204,0.25170495959874245,-0.6048009638951245,-0.7975501035896743,-0.015949191785796384,0.45472828026538425,-0.3599276825042347,-0.7323887974882097,0.11989823952072967,2.8557557026843536,-0.4199119328370344,0.8797499948322487,1.3279431624639007,0.5770071775774535,0.03888935479482263,0.9021855262027676,-0.2714249570573372,-0.33023269302803204,0.7193596211985692,1.3076315066448148,0.1730932216945844,-0.7001544799726708,-0.7323887974882097,0.37968874363881105,-1.904873795283732,-0.33023269302803204,3.3188565054042503,0.19945282519176055,0.429857390182749,-0.015949191785796384,0.22565616698772623,-0.1560737352527625
| 3,120
|
Sensorimotor neuropathy
| 9
| 30
| 2.269471
| 0.02324
|
P00403,Q9Y2R0,P00846,P41440,Q9NR77,P07196,Q13217,O60313,O95831
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
225,2,9,204,80,119,314,340,401
|
730,2129,340,401,225,9,3014,862,119,1278,2932,1776,1087,204,1521,1401,502,2764,2631,2398,314,1002,2938,1062,1064,80,2185,426,2,564
|
0.37968874363881105,-0.3599276825042347,0.8797499948322487,0.7657939331769242,1.2254037240919913,4.375070750907427,-1.5057183812598571,0.2776008882438347,2.0181394542083764,0.03888935479482263,-1.1735319573878251,-0.18463413695639644,0.1465756160978675,1.3279431624639007,-0.07147184402573621,-0.015949191785796384,0.6249765506068089,-0.8636557041179473,-0.7001544799726708,-0.5114114008305259,0.9688011263013478,0.19945282519176055,-1.1735319573878251,0.1730932216945844,0.1730932216945844,2.610061135094578,-0.3599276825042347,0.7426388328088186,5.247956016095376,0.5528233698913807
| 3,120
|
Membrane lipid biosynthetic process
| 12
| 22
| 2.246799
| 0.024653
|
Q06136,Q99805,Q53H12,Q8NBX0,Q5H8A4,Q13510,Q96S52,Q92643,O95470,O15269,Q9P035,Q969N2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,131,450,5,248,71,302,640,107,587,511,385
|
2885,587,2129,2502,107,1902,1905,1665,130,838,71,450,248,664,5,640,385,302,131,3005,511,2241
|
-1.0679010003564908,0.5040506253802524,-0.3599276825042347,-0.6048009638951245,2.1535101765609372,-0.24230752653304063,-0.24230752653304063,-0.12769463103528156,1.9312396535039034,0.30334561141450944,2.683879218936928,0.6959550565518066,1.1626777008156755,0.45472828026538425,4.641924981314761,0.4794588708276966,0.8117366781974475,1.012646583383761,1.9312396535039034,-1.429818003064028,0.6249765506068089,-0.38981994606341763
| 3,120
|
Sterol metabolic process
| 13
| 37
| 2.245754
| 0.02472
|
Q14739,Q16850,P49748,P37268,P16435,Q15392,P04035,O15118,Q14534,P48449,Q8WTV0,P35610,O75845
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
195,65,344,68,327,230,267,112,172,85,30,122,310
|
112,588,310,1899,2616,267,1902,1510,402,327,2931,122,68,3016,2391,85,344,1843,1967,777,3074,1529,1664,600,2766,172,195,2269,1541,230,1982,686,65,30,699,1173,3061
|
2.1200791235371135,0.5040506253802524,0.9688011263013478,-0.24230752653304063,-0.7001544799726708,1.0990194895203063,-0.24230752653304063,-0.07147184402573621,0.7657939331769242,0.9245051560552161,-1.1735319573878251,2.0009038654063014,2.770727945453716,-1.5057183812598571,-0.5114114008305259,2.489102096014749,0.8797499948322487,-0.21337800008247138,-0.2714249570573372,0.3543879449769868,-1.9889367176870343,-0.07147184402573621,-0.12769463103528156,0.5040506253802524,-0.8636557041179473,1.487036333627781,1.388303199401113,-0.4199119328370344,-0.07147184402573621,1.2045970593385245,-0.2714249570573372,0.429857390182749,2.8134649963657146,3.4053666094719595,0.429857390182749,0.11989823952072967,-1.822282220676953
| 3,120
|
Liposaccharide metabolic process
| 7
| 17
| 2.245729
| 0.024721
|
Q99805,Q8NBX0,Q96S52,P17900,Q9NZD2,Q5H8A4,Q969N2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,5,302,268,252,248,385
|
2502,1902,1124,898,2070,2618,476,268,1665,838,248,5,640,385,302,131,252
|
-0.6048009638951245,-0.24230752653304063,0.11989823952072967,0.25170495959874245,-0.33023269302803204,-0.7001544799726708,0.6487648093812882,1.0990194895203063,-0.12769463103528156,0.30334561141450944,1.1626777008156755,4.641924981314761,0.4794588708276966,0.8117366781974475,1.012646583383761,1.9312396535039034,1.1626777008156755
| 3,120
|
Organic hydroxy compound transport
| 7
| 30
| 2.239123
| 0.025148
|
O95486,P53985,O15118,P30536,Q14728,P35610,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
217,104,112,25,58,122,30
|
1636,112,1268,217,1389,987,1905,1963,1282,25,122,104,3074,912,2718,58,2217,1552,2924,30,1622,723,3066,303,1213,1170,2241,3012,1173,2057
|
-0.12769463103528156,2.1200791235371135,0.03888935479482263,1.2667156015614143,-0.015949191785796384,0.19945282519176055,-0.24230752653304063,-0.2714249570573372,0.03888935479482263,3.607914396820148,2.0009038654063014,2.186673620608435,-1.9889367176870343,0.25170495959874245,-0.7975501035896743,2.8837057870744482,-0.38981994606341763,-0.07147184402573621,-1.1380519309620947,3.4053666094719595,-0.09949469747666943,0.4048447144069418,-1.904873795283732,1.012646583383761,0.09305929398318494,0.11989823952072967,-0.38981994606341763,-1.4676135569727793,0.11989823952072967,-0.3007325721587227
| 3,120
|
Oxidative phosphorylation
| 16
| 62
| 2.236678
| 0.025307
|
P24539,P00403,Q7KZN9,Q9UDW1,P36543,Q9Y6N1,O14548,P00846,P14406,O96000,O14949,Q93050,P14927,O75964,P22695,P13073
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
129,225,185,36,262,198,199,9,41,178,19,279,147,52,274,57
|
3021,2062,199,19,3104,2780,2930,1178,2551,1385,568,52,529,444,1587,2503,178,225,9,3014,766,1507,864,2711,57,41,147,1771,2584,288,1081,769,477,274,129,1773,2147,2808,2309,711,262,1460,2814,2032,3040,3029,2632,1845,2433,2978,744,745,958,185,2961,279,2911,36,1572,362,565,198
|
-1.5441372114598413,-0.33023269302803204,1.3481584340693418,3.80054934068688,-2.9227381542310105,-0.8970706209351134,-1.1735319573878251,0.09305929398318494,-0.6363634842619023,-0.015949191785796384,0.5285049852239486,2.925271544766199,0.5770071775774535,0.6959550565518066,-0.09949469747666943,-0.6048009638951245,1.4674726459409988,1.2254037240919913,4.375070750907427,-1.5057183812598571,0.3543879449769868,-0.07147184402573621,0.2776008882438347,-0.7975501035896743,2.897608649302585,3.139985047591634,1.7150000315769534,-0.18463413695639644,-0.6681470252093221,1.0344030160862734,0.1465756160978675,0.3543879449769868,0.6487648093812882,1.0775884567819758,1.9312396535039034,-0.18463413695639644,-0.3599276825042347,-0.9307313466100875,-0.45020613666046194,0.4048447144069418,1.120344057573255,-0.043624015597528217,-0.9307313466100875,-0.3007325721587227,-1.6613267134213334,-1.582874889859472,-0.7001544799726708,-0.21337800008247138,-0.5423276822514903,-1.3182411457175676,0.37968874363881105,0.37968874363881105,0.22565616698772623,1.4280724450354945,-1.2453206396228493,1.0775884567819758,-1.1028428854778956,3.2176279524756564,-0.07147184402573621,0.8571974386256007,0.5528233698913807,1.3682781678569051
| 3,120
|
Retinal degeneration
| 13
| 54
| 2.234731
| 0.025435
|
O14773,Q13510,P51648,Q7LGA3,P50897,Q9H0F7,Q96F07,Q9NW15,O75503,Q10713,Q96PZ0,O60313,O75648
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,71,47,17,48,352,464,410,115,55,491,340,498
|
2498,66,2298,340,2426,115,1581,498,824,3023,1766,1902,861,2801,1646,2554,499,1707,2078,2080,1460,803,1966,2715,48,47,2630,626,833,1971,1405,1532,55,71,1001,1615,17,1303,638,877,1099,1063,964,1362,464,491,2111,1751,352,849,2980,410,978,1437
|
-0.6048009638951245,2.7850237629841788,-0.45020613666046194,0.8797499948322487,-0.5423276822514903,2.086376421063753,-0.09949469747666943,0.6249765506068089,0.30334561141450944,-1.5441372114598413,-0.18463413695639644,-0.24230752653304063,0.2776008882438347,-0.9307313466100875,-0.12769463103528156,-0.6363634842619023,0.6249765506068089,-0.1560737352527625,-0.33023269302803204,-0.33023269302803204,-0.043624015597528217,0.32894076142978074,-0.2714249570573372,-0.7975501035896743,2.993609575094583,3.0071390894611416,-0.7001544799726708,0.4794588708276966,0.30334561141450944,-0.2714249570573372,-0.015949191785796384,-0.07147184402573621,2.9114638007546514,2.683879218936928,0.19945282519176055,-0.09949469747666943,3.811591163952668,0.03888935479482263,0.4794588708276966,0.2776008882438347,0.1465756160978675,0.1730932216945844,0.22565616698772623,0.011554613903006978,0.6724238788270614,0.6487648093812882,-0.33023269302803204,-0.1560737352527625,0.8797499948322487,0.30334561141450944,-1.3182411457175676,0.7657939331769242,0.22565616698772623,-0.015949191785796384
| 3,120
|
Aganglionic megacolon
| 8
| 18
| 2.221788
| 0.026298
|
Q92890,P42892,Q9BXW9,Q15427,P21964,Q9H0F7,Q96EK5,Q10713
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
642,102,693,602,146,352,541,55
|
1698,146,1397,2666,990,102,1466,1469,55,602,642,541,2282,693,352,889,699,1436
|
-0.1560737352527625,1.733451983355156,-0.015949191785796384,-0.7323887974882097,0.19945282519176055,2.26843717639146,-0.043624015597528217,-0.043624015597528217,2.9114638007546514,0.5040506253802524,0.4794588708276966,0.5770071775774535,-0.4199119328370344,0.429857390182749,0.8797499948322487,0.2776008882438347,0.429857390182749,-0.015949191785796384
| 3,120
|
Retinopathy
| 9
| 26
| 2.207247
| 0.027297
|
Q9NZ08,Q9NYB0,Q99496,P00846,O95169,O43819,P51648,Q15555,Q5H8A4
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
100,361,524,9,444,295,47,393,248
|
1265,295,2502,1178,444,896,1040,9,1901,827,549,2554,2762,1087,1399,47,1523,2557,393,248,1611,2173,524,2705,361,100
|
0.03888935479482263,1.012646583383761,-0.6048009638951245,0.09305929398318494,0.6959550565518066,0.25170495959874245,0.1730932216945844,4.375070750907427,-0.24230752653304063,0.30334561141450944,0.5528233698913807,-0.6363634842619023,-0.8636557041179473,0.1465756160978675,-0.015949191785796384,3.0071390894611416,-0.07147184402573621,-0.6363634842619023,0.7888261461963076,1.1626777008156755,-0.09949469747666943,-0.3599276825042347,0.6010577855594291,-0.764852983812969,0.8571974386256007,2.3167291137840786
| 3,120
|
Glycosyltransferase
| 7
| 31
| 2.203805
| 0.027538
|
Q13126,O43505,Q96L58,Q10472,P43490,Q9BT22,Q9H6U8
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
133,141,175,214,89,319,188
|
2249,141,858,2502,2684,2304,1902,1042,2071,1592,2019,1832,334,1340,89,1649,778,717,214,838,133,2701,2046,1100,175,319,1366,2117,188,1261,1944
|
-0.4199119328370344,1.8424923729445961,0.2776008882438347,-0.6048009638951245,-0.764852983812969,-0.45020613666046194,-0.24230752653304063,0.1730932216945844,-0.33023269302803204,-0.09949469747666943,-0.3007325721587227,-0.21337800008247138,0.9021855262027676,0.011554613903006978,2.427254953547532,-0.12769463103528156,0.3543879449769868,0.4048447144069418,1.287222609209894,0.30334561141450944,1.9136403131944537,-0.764852983812969,-0.3007325721587227,0.1465756160978675,1.487036333627781,0.9688011263013478,0.011554613903006978,-0.33023269302803204,1.4280724450354945,0.06605695177290508,-0.24230752653304063
| 3,120
|
Protein transmembrane transport
| 12
| 24
| 2.203514
| 0.027559
|
Q07820,Q9NS69,O60830,P31751,P49755,Q3ZCQ8,O75298,O14925,Q15388,Q15629,O95831,O43615
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
503,35,3,570,625,240,81,113,346,121,401,615
|
113,615,3070,3,81,1704,2069,401,1077,2802,570,625,2922,1659,2588,503,346,121,240,1553,1425,1569,35,673
|
2.1032619844886535,0.4794588708276966,-1.9889367176870343,5.022002691408248,2.5801554718278767,-0.1560737352527625,-0.33023269302803204,0.7657939331769242,0.1465756160978675,-0.9307313466100875,0.5285049852239486,0.4794588708276966,-1.1380519309620947,-0.12769463103528156,-0.6681470252093221,0.6249765506068089,0.8797499948322487,2.0181394542083764,1.1836886940989366,-0.07147184402573621,-0.015949191785796384,-0.07147184402573621,3.255890605195437,0.45472828026538425
| 3,120
|
Cristae formation
| 11
| 20
| 2.203428
| 0.027565
|
O75947,O75431,P24539,Q9NX63,P00846,Q5XKP0,Q16891,O75964,P36542,Q13505,Q9Y512
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
568,618,129,757,9,270,603,52,711,88,459
|
618,568,52,9,766,129,1773,711,2667,2032,2632,1845,88,603,270,1300,2536,975,757,459
|
0.4794588708276966,0.5285049852239486,2.925271544766199,4.375070750907427,0.3543879449769868,1.9312396535039034,-0.18463413695639644,0.4048447144069418,-0.7323887974882097,-0.3007325721587227,-0.7001544799726708,-0.21337800008247138,2.4428044126478934,0.5040506253802524,1.0990194895203063,0.03888935479482263,-0.6048009638951245,0.22565616698772623,0.37968874363881105,0.6959550565518066
| 3,120
|
C4 dicarboxylate transport
| 6
| 8
| 2.202676
| 0.027618
|
Q9H936,Q8TDW0,O75746,Q9UJS0,Q02978,Q9UBX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
496,423,567,411,432,157
|
567,626,432,1415,423,496,157,411
|
0.5285049852239486,0.4794588708276966,0.7193596211985692,-0.015949191785796384,0.7426388328088186,0.6487648093812882,1.621506944075928,0.7657939331769242
| 3,120
|
Cellular modified amino acid metabolic process
| 9
| 56
| 2.182051
| 0.029106
|
P23786,Q9H7Z7,Q9H2D1,Q8NCC3,P00374,Q9BVG9,Q9UHG3,O60725,Q8IYS1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
98,135,40,11,44,144,18,83,84
|
1823,2709,2578,858,83,1179,621,44,1388,2735,2252,1041,2985,1510,2346,2919,2759,899,327,2738,2687,98,1455,1964,1648,1130,1284,1775,204,1464,1596,2998,2626,2999,738,403,1663,2875,1148,2767,84,1062,11,2567,1307,1562,3066,1998,144,1213,40,135,697,331,18,728
|
-0.21337800008247138,-0.7975501035896743,-0.6681470252093221,0.2776008882438347,2.550029118133312,0.09305929398318494,0.4794588708276966,3.087373369880343,-0.015949191785796384,-0.8304832815585822,-0.4199119328370344,0.1730932216945844,-1.3551362796599622,-0.07147184402573621,-0.4807050971530273,-1.1380519309620947,-0.8636557041179473,0.25170495959874245,0.9245051560552161,-0.8304832815585822,-0.764852983812969,2.3167291137840786,-0.043624015597528217,-0.2714249570573372,-0.12769463103528156,0.11989823952072967,0.03888935479482263,-0.18463413695639644,1.3279431624639007,-0.043624015597528217,-0.09949469747666943,-1.3923270876756626,-0.7001544799726708,-1.3923270876756626,0.37968874363881105,0.7657939331769242,-0.12769463103528156,-1.033222533253154,0.11989823952072967,-0.8636557041179473,2.534882233082504,0.1730932216945844,4.159435423734304,-0.6363634842619023,0.03888935479482263,-0.07147184402573621,-1.904873795283732,-0.2714249570573372,1.77011455390589,0.09305929398318494,3.1530306783954622,1.8959665059951594,0.429857390182749,0.9245051560552161,3.811591163952668,0.4048447144069418
| 3,120
|
Limb muscle weakness
| 16
| 85
| 2.179358
| 0.029305
|
Q7RTS9,Q14739,Q15650,P35670,P50402,Q9BQT8,Q13126,Q13510,P00846,P50336,Q15067,Q9NR77,O75298,Q99720,P07196,P36551
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
196,195,291,255,290,101,133,71,9,170,300,80,81,20,119,127
|
1578,1378,587,2129,295,81,1899,429,9,1766,2505,862,985,119,2617,1450,2802,1079,1646,623,770,2808,2623,255,127,1189,1087,2082,2084,1966,170,290,1840,2207,1342,502,2630,1781,2764,2631,2519,1914,2591,2093,2398,2357,133,433,71,2162,1199,1200,2401,195,2790,300,1002,1793,291,1794,1474,1249,1731,196,2403,687,638,1741,1931,2567,668,1064,2279,1422,2280,3092,1365,524,20,101,1313,80,1631,564,652
|
-0.09949469747666943,-0.015949191785796384,0.5040506253802524,-0.3599276825042347,1.012646583383761,2.5801554718278767,-0.24230752653304063,0.7193596211985692,4.375070750907427,-0.18463413695639644,-0.6048009638951245,0.2776008882438347,0.19945282519176055,2.0181394542083764,-0.7001544799726708,-0.043624015597528217,-0.9307313466100875,0.1465756160978675,-0.12769463103528156,0.4794588708276966,0.3543879449769868,-0.9307313466100875,-0.7001544799726708,1.1415631395121968,1.9662172504490403,0.09305929398318494,0.1465756160978675,-0.33023269302803204,-0.33023269302803204,-0.2714249570573372,1.5065101151687854,1.0344030160862734,-0.21337800008247138,-0.38981994606341763,0.011554613903006978,0.6249765506068089,-0.7001544799726708,-0.18463413695639644,-0.8636557041179473,-0.7001544799726708,-0.6048009638951245,-0.24230752653304063,-0.6681470252093221,-0.33023269302803204,-0.5114114008305259,-0.4807050971530273,1.9136403131944537,0.7193596211985692,2.683879218936928,-0.3599276825042347,0.09305929398318494,0.09305929398318494,-0.5114114008305259,1.388303199401113,-0.8970706209351134,1.012646583383761,0.19945282519176055,-0.18463413695639644,1.0344030160862734,-0.18463413695639644,-0.043624015597528217,0.06605695177290508,-0.1560737352527625,1.388303199401113,-0.5114114008305259,0.429857390182749,0.4794588708276966,-0.1560737352527625,-0.24230752653304063,-0.6363634842619023,0.45472828026538425,0.1730932216945844,-0.4199119328370344,-0.015949191785796384,-0.4199119328370344,-2.2954806321994075,0.011554613903006978,0.6010577855594291,3.80054934068688,2.2845974095289043,0.03888935479482263,2.610061135094578,-0.09949469747666943,0.5528233698913807,0.4794588708276966
| 3,120
|
Steroid biosynthesis
| 8
| 22
| 2.178105
| 0.029398
|
Q16850,Q14739,P37268,Q15392,Q53GQ0,P04035,P48449,O75845
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
65,195,68,230,205,267,85,310
|
310,2616,267,402,68,85,1967,777,1664,2766,195,1541,230,1982,686,65,205,2107,887,1567,699,3061
|
0.9688011263013478,-0.7001544799726708,1.0990194895203063,0.7657939331769242,2.770727945453716,2.489102096014749,-0.2714249570573372,0.3543879449769868,-0.12769463103528156,-0.8636557041179473,1.388303199401113,-0.07147184402573621,1.2045970593385245,-0.2714249570573372,0.429857390182749,2.8134649963657146,1.3279431624639007,-0.33023269302803204,0.2776008882438347,-0.07147184402573621,0.429857390182749,-1.822282220676953
| 3,120
|
Phosphatidylinositol biosynthetic process
| 8
| 20
| 2.173695
| 0.029728
|
Q5H8A4,Q96S52,Q969N2,Q10713,Q9NX62,Q96N66,Q8TBX8,O00459
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
248,302,385,55,224,153,219,339
|
2755,339,2548,2502,2782,1183,381,999,55,248,665,219,640,385,153,1163,302,1999,1817,224
|
-0.8636557041179473,0.8797499948322487,-0.6363634842619023,-0.6048009638951245,-0.8970706209351134,0.09305929398318494,0.8117366781974475,0.19945282519176055,2.9114638007546514,1.1626777008156755,0.45472828026538425,1.2667156015614143,0.4794588708276966,0.8117366781974475,1.640372274402174,0.11989823952072967,1.012646583383761,-0.2714249570573372,-0.18463413695639644,1.2461096037129336
| 3,120
|
Mitochondrial complex iv assembly
| 7
| 13
| 2.172895
| 0.029788
|
P00403,Q9Y2R0,P20674,Q9Y6N1,P14406,Q7KZN9,P13073
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
225,2,288,198,41,185,57
|
2062,295,225,864,2711,57,41,1771,288,185,3111,2,198
|
-0.33023269302803204,1.012646583383761,1.2254037240919913,0.2776008882438347,-0.7975501035896743,2.897608649302585,3.139985047591634,-0.18463413695639644,1.0344030160862734,1.4280724450354945,-3.409934469339057,5.247956016095376,1.3682781678569051
| 3,120
|
Glycosaminoglycan metabolism
| 6
| 15
| 2.171853
| 0.029867
|
O43505,Q96L58,P15586,Q7LGA3,Q8NCH0,P54802
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
141,175,238,17,117,276
|
2299,141,2070,2618,591,238,476,276,838,17,117,369,175,1164,2572
|
-0.45020613666046194,1.8424923729445961,-0.33023269302803204,-0.7001544799726708,0.5040506253802524,1.1836886940989366,0.6487648093812882,1.0775884567819758,0.30334561141450944,3.811591163952668,2.069421914151396,0.8345267182780652,1.487036333627781,0.11989823952072967,-0.6363634842619023
| 3,120
|
FAD/NAD(P)-binding domain superfamily [IPR036188]
| 6
| 18
| 2.170284
| 0.029985
|
Q9H9P8,P50336,Q16134,Q14534,Q9UHG3,Q96CU9
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
396,170,269,172,18,91
|
1502,401,1388,2428,2931,2808,1237,1462,170,1522,172,269,1796,534,813,91,396,18
|
-0.07147184402573621,0.7657939331769242,-0.015949191785796384,-0.5423276822514903,-1.1735319573878251,-0.9307313466100875,0.06605695177290508,-0.043624015597528217,1.5065101151687854,-0.07147184402573621,1.487036333627781,1.0990194895203063,-0.18463413695639644,0.5770071775774535,0.32894076142978074,2.4116463573658264,0.7888261461963076,3.811591163952668
| 3,120
|
Incoordination
| 17
| 72
| 2.16927
| 0.030062
|
Q7RTS9,Q9NZJ7,O14773,Q13510,P21912,P00846,Q15067,O43819,Q9NR77,Q99707,Q9H0F7,O75503,Q10713,O95140,Q13501,Q01105,P35670
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
196,426,66,71,477,9,300,295,80,372,352,115,55,429,433,189,255
|
1225,2834,66,1034,2063,675,295,2197,617,115,2301,1271,429,1961,9,1902,985,1079,3002,477,2349,2808,2623,255,1189,1087,803,1519,1521,1342,502,2764,2631,2519,833,189,1346,1244,1194,55,433,71,2162,1200,300,1793,1151,843,1355,2220,196,2368,1303,1931,1063,815,2282,1482,1365,1164,372,2111,352,849,2980,80,1321,426,1172,2966,2572,1436
|
0.06605695177290508,-0.9646412623937256,2.7850237629841788,0.1730932216945844,-0.33023269302803204,0.429857390182749,1.012646583383761,-0.38981994606341763,0.4794588708276966,2.086376421063753,-0.45020613666046194,0.03888935479482263,0.7193596211985692,-0.2714249570573372,4.375070750907427,-0.24230752653304063,0.19945282519176055,0.1465756160978675,-1.429818003064028,0.6487648093812882,-0.4807050971530273,-0.9307313466100875,-0.7001544799726708,1.1415631395121968,0.09305929398318494,0.1465756160978675,0.32894076142978074,-0.07147184402573621,-0.07147184402573621,0.011554613903006978,0.6249765506068089,-0.8636557041179473,-0.7001544799726708,-0.6048009638951245,0.30334561141450944,1.408234353636559,0.011554613903006978,0.06605695177290508,0.09305929398318494,2.9114638007546514,0.7193596211985692,2.683879218936928,-0.3599276825042347,0.09305929398318494,1.012646583383761,-0.18463413695639644,0.11989823952072967,0.30334561141450944,0.011554613903006978,-0.38981994606341763,1.388303199401113,-0.4807050971530273,0.03888935479482263,-0.24230752653304063,0.1730932216945844,0.32894076142978074,-0.4199119328370344,-0.043624015597528217,0.011554613903006978,0.11989823952072967,0.8345267182780652,-0.33023269302803204,0.8797499948322487,0.30334561141450944,-1.3182411457175676,2.610061135094578,0.03888935479482263,0.7426388328088186,0.11989823952072967,-1.2453206396228493,-0.6363634842619023,-0.015949191785796384
| 3,120
|
Amide transport
| 10
| 34
| 2.164914
| 0.030394
|
Q9NZJ7,Q9H2D1,P53985,P41440,Q8N5M9,Q9NZD2,P08183,Q16836,P50416,Q15907
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
426,40,104,204,338,252,22,347,403,61
|
2576,1265,940,1893,569,1590,799,22,1043,1186,1905,2841,1087,204,403,104,2520,2091,2525,2718,1409,659,2160,61,2271,347,1301,338,436,3066,40,252,426,2241
|
-0.6681470252093221,0.03888935479482263,0.22565616698772623,-0.24230752653304063,0.5285049852239486,-0.09949469747666943,0.32894076142978074,3.744867759885806,0.1730932216945844,0.09305929398318494,-0.24230752653304063,-0.9646412623937256,0.1465756160978675,1.3279431624639007,0.7657939331769242,2.186673620608435,-0.6048009638951245,-0.33023269302803204,-0.6048009638951245,-0.7975501035896743,-0.015949191785796384,0.45472828026538425,-0.3599276825042347,2.8557557026843536,-0.4199119328370344,0.8797499948322487,0.03888935479482263,0.9021855262027676,0.7193596211985692,-1.904873795283732,3.1530306783954622,1.1626777008156755,0.7426388328088186,-0.38981994606341763
| 3,120
|
Muscle spasm
| 12
| 62
| 2.163239
| 0.030523
|
Q15165,Q9UQN3,P23786,P53985,P00846,P51530,Q9H6K4,Q9NR77,O75298,Q709C8,P07196,Q5H8A4
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,162,98,104,9,297,111,80,81,307,119,248
|
1700,1955,2197,81,617,429,1588,2734,2251,9,1902,2505,862,898,1042,119,3055,1043,2428,1272,2985,1079,3088,98,1648,1239,1087,2082,1965,344,1841,297,104,502,1781,2764,2631,1346,1194,2399,433,1199,1,1474,248,2220,307,1560,1064,539,1482,1365,3066,1104,2910,111,849,80,563,162,2983,652
|
-0.1560737352527625,-0.2714249570573372,-0.38981994606341763,2.5801554718278767,0.4794588708276966,0.7193596211985692,-0.09949469747666943,-0.8304832815585822,-0.4199119328370344,4.375070750907427,-0.24230752653304063,-0.6048009638951245,0.2776008882438347,0.25170495959874245,0.1730932216945844,2.0181394542083764,-1.7815233696066426,0.1730932216945844,-0.5423276822514903,0.03888935479482263,-1.3551362796599622,0.1465756160978675,-2.2504606922272252,2.3167291137840786,-0.12769463103528156,0.06605695177290508,0.1465756160978675,-0.33023269302803204,-0.2714249570573372,0.8797499948322487,-0.21337800008247138,1.012646583383761,2.186673620608435,0.6249765506068089,-0.18463413695639644,-0.8636557041179473,-0.7001544799726708,0.011554613903006978,0.09305929398318494,-0.5114114008305259,0.7193596211985692,0.09305929398318494,5.344943653484487,-0.043624015597528217,1.1626777008156755,-0.38981994606341763,0.9907796360095241,-0.07147184402573621,0.1730932216945844,0.5770071775774535,-0.043624015597528217,0.011554613903006978,-1.904873795283732,0.1465756160978675,-1.1028428854778956,2.1368283516262,0.30334561141450944,2.610061135094578,0.5528233698913807,1.5835213327153648,-1.3182411457175676,0.4794588708276966
| 3,120
|
Slender long bone
| 7
| 12
| 2.155688
| 0.031108
|
Q9Y487,P37268,Q96L58,Q32P28,Q96MF7,Q969N2,Q9H0W5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
362,68,175,366,387,385,458
|
2462,68,480,1794,366,2675,385,175,387,458,1167,362
|
-0.5734566251984043,2.770727945453716,0.6487648093812882,-0.18463413695639644,0.8345267182780652,-0.7323887974882097,0.8117366781974475,1.487036333627781,0.8117366781974475,0.6959550565518066,0.11989823952072967,0.8571974386256007
| 3,120
|
Fatty acid transport
| 6
| 15
| 2.155372
| 0.031133
|
P23786,P31751,O43808,P07814,O43772,P50416
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
98,570,332,14,15,403
|
15,332,1589,2735,799,14,2255,2142,98,1282,593,570,1131,403,1732
|
3.898819192738822,0.9021855262027676,-0.09949469747666943,-0.8304832815585822,0.32894076142978074,3.9095867503469988,-0.4199119328370344,-0.3599276825042347,2.3167291137840786,0.03888935479482263,0.5040506253802524,0.5285049852239486,0.11989823952072967,0.7657939331769242,-0.1560737352527625
| 3,120
|
Regulation of protein secretion
| 15
| 38
| 2.147396
| 0.031762
|
Q16850,O95486,P49755,P55011,O95563,Q15334,P53985,P04035,Q96KC8,Q8NE86,Q8N5M9,Q32P28,Q16836,P53367,P50416
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,217,625,626,569,575,104,267,211,436,338,366,347,245,403
|
1265,730,1893,2756,217,569,1590,267,1043,1275,1186,1905,1188,2841,1285,1087,625,403,245,104,626,2520,2525,2718,1723,1409,575,2271,347,65,366,1301,338,436,211,1482,694,1576
|
0.03888935479482263,0.37968874363881105,-0.24230752653304063,-0.8636557041179473,1.2667156015614143,0.5285049852239486,-0.09949469747666943,1.0990194895203063,0.1730932216945844,0.03888935479482263,0.09305929398318494,-0.24230752653304063,0.09305929398318494,-0.9646412623937256,0.03888935479482263,0.1465756160978675,0.4794588708276966,0.7657939331769242,1.1626777008156755,2.186673620608435,0.4794588708276966,-0.6048009638951245,-0.6048009638951245,-0.7975501035896743,-0.1560737352527625,-0.015949191785796384,0.5285049852239486,-0.4199119328370344,0.8797499948322487,2.8134649963657146,0.8345267182780652,0.03888935479482263,0.9021855262027676,0.7193596211985692,1.3076315066448148,-0.043624015597528217,0.429857390182749,-0.07147184402573621
| 3,120
|
Hepatic failure
| 6
| 48
| 2.140198
| 0.032339
|
P23786,Q13510,P00846,O43772,Q10713,P22830
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
98,71,9,15,55,24
|
1891,112,15,3070,2300,1704,498,310,1642,9,1901,3014,1902,1333,2253,1507,2428,2663,24,98,1282,2665,255,3016,1461,1087,1709,403,502,2631,1849,55,2158,71,2271,347,1614,1354,1364,2909,1168,1815,1259,2539,758,2336,890,2610
|
-0.24230752653304063,2.1200791235371135,3.898819192738822,-1.9889367176870343,-0.45020613666046194,-0.1560737352527625,0.6249765506068089,0.9688011263013478,-0.12769463103528156,4.375070750907427,-0.24230752653304063,-1.5057183812598571,-0.24230752653304063,0.011554613903006978,-0.4199119328370344,-0.07147184402573621,-0.5423276822514903,-0.7323887974882097,3.6997454234904574,2.3167291137840786,0.03888935479482263,-0.7323887974882097,1.1415631395121968,-1.5057183812598571,-0.043624015597528217,0.1465756160978675,-0.1560737352527625,0.7657939331769242,0.6249765506068089,-0.7001544799726708,-0.21337800008247138,2.9114638007546514,-0.3599276825042347,2.683879218936928,-0.4199119328370344,0.8797499948322487,-0.09949469747666943,0.011554613903006978,0.011554613903006978,-1.1028428854778956,0.11989823952072967,-0.18463413695639644,0.06605695177290508,-0.6048009638951245,0.37968874363881105,-0.45020613666046194,0.2776008882438347,-0.6681470252093221
| 3,120
|
Icosanoid metabolic process
| 6
| 18
| 2.137527
| 0.032555
|
Q8N8N7,Q9H7Z7,Q8NCG7,P07099,Q8N4Q0,P09960
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
69,135,301,10,278,213
|
548,799,10,213,2142,2620,2783,3010,300,2322,1062,278,69,301,1622,1998,135,1886
|
0.5528233698913807,0.32894076142978074,4.209515969875745,1.287222609209894,-0.3599276825042347,-0.7001544799726708,-0.8970706209351134,-1.4676135569727793,1.012646583383761,-0.45020613666046194,0.1730932216945844,1.0775884567819758,2.7130355927853143,1.012646583383761,-0.09949469747666943,-0.2714249570573372,1.8959665059951594,-0.21337800008247138
| 3,120
|
Aplasia hypoplasia involving the vertebral column
| 7
| 16
| 2.135197
| 0.032745
|
Q7RTS9,Q14739,Q96HY6,Q8TAA9,P16278,P08236,O95831
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
196,195,558,134,476,591,401
|
1034,2550,401,1124,591,1273,476,1458,595,195,1982,1614,196,134,558,1815
|
0.1730932216945844,-0.6363634842619023,0.7657939331769242,0.11989823952072967,0.5040506253802524,0.03888935479482263,0.6487648093812882,-0.043624015597528217,0.5040506253802524,1.388303199401113,-0.2714249570573372,-0.09949469747666943,1.388303199401113,1.8959665059951594,0.5528233698913807,-0.18463413695639644
| 3,120
|
Proton transmembrane transport
| 11
| 46
| 2.131995
| 0.033007
|
P24539,P00403,Q9UDW1,P36543,O14548,P00846,Q8TAD4,O75964,Q7KZN9,Q13423,P13073
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,225,36,262,199,9,208,52,185,246,57
|
2062,199,940,1763,2930,568,52,225,9,3014,862,1229,766,1507,2711,1079,57,288,1081,769,129,1773,3090,2309,711,262,1460,2814,2032,1842,2632,1845,2433,1720,1469,246,185,208,3066,454,1164,496,36,2572,1572,853
|
-0.33023269302803204,1.3481584340693418,0.22565616698772623,-0.18463413695639644,-1.1735319573878251,0.5285049852239486,2.925271544766199,1.2254037240919913,4.375070750907427,-1.5057183812598571,0.2776008882438347,0.06605695177290508,0.3543879449769868,-0.07147184402573621,-0.7975501035896743,0.1465756160978675,2.897608649302585,1.0344030160862734,0.1465756160978675,0.3543879449769868,1.9312396535039034,-0.18463413695639644,-2.2954806321994075,-0.45020613666046194,0.4048447144069418,1.120344057573255,-0.043624015597528217,-0.9307313466100875,-0.3007325721587227,-0.21337800008247138,-0.7001544799726708,-0.21337800008247138,-0.5423276822514903,-0.1560737352527625,-0.043624015597528217,1.1626777008156755,1.4280724450354945,1.3076315066448148,-1.904873795283732,0.6959550565518066,0.11989823952072967,0.6487648093812882,3.2176279524756564,-0.6363634842619023,-0.07147184402573621,0.30334561141450944
| 3,120
|
Sterol biosynthetic process
| 9
| 26
| 2.119115
| 0.034081
|
Q16850,Q14739,P37268,P16435,Q15392,P04035,Q14534,P48449,O75845
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,195,68,327,230,267,172,85,310
|
588,310,1899,2616,267,1510,402,327,68,2391,85,1843,1967,777,1664,600,2766,172,195,1541,230,1982,686,65,699,3061
|
0.5040506253802524,0.9688011263013478,-0.24230752653304063,-0.7001544799726708,1.0990194895203063,-0.07147184402573621,0.7657939331769242,0.9245051560552161,2.770727945453716,-0.5114114008305259,2.489102096014749,-0.21337800008247138,-0.2714249570573372,0.3543879449769868,-0.12769463103528156,0.5040506253802524,-0.8636557041179473,1.487036333627781,1.388303199401113,-0.07147184402573621,1.2045970593385245,-0.2714249570573372,0.429857390182749,2.8134649963657146,0.429857390182749,-1.822282220676953
| 3,120
|
Polydactyly
| 19
| 43
| 2.117724
| 0.034198
|
O60826,Q8NCM8,P21964,Q13045,Q9BXW9,Q15067,Q9UBM7,Q9UM00,Q10713,Q9UHX1,O75845,Q14739,O43924,Q9H0F7,O00459,Q92890,Q86XI2,Q8IY17,Q5H8A4
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
391,667,146,405,693,300,699,441,55,583,310,195,79,352,339,642,484,638,248
|
339,1698,79,391,310,896,1040,1235,2806,146,1514,1397,2629,1466,683,870,837,55,405,2557,195,1980,300,248,1735,484,638,1805,667,2724,642,1563,2332,2000,693,352,1017,2980,699,583,1111,441,1886
|
0.8797499948322487,-0.1560737352527625,2.610061135094578,0.7888261461963076,0.9688011263013478,0.25170495959874245,0.1730932216945844,0.06605695177290508,-0.9307313466100875,1.733451983355156,-0.07147184402573621,-0.015949191785796384,-0.7001544799726708,-0.043624015597528217,0.429857390182749,0.2776008882438347,0.30334561141450944,2.9114638007546514,0.7657939331769242,-0.6363634842619023,1.388303199401113,-0.2714249570573372,1.012646583383761,1.1626777008156755,-0.1560737352527625,0.6487648093812882,0.4794588708276966,-0.18463413695639644,0.45472828026538425,-0.7975501035896743,0.4794588708276966,-0.07147184402573621,-0.45020613666046194,-0.2714249570573372,0.429857390182749,0.8797499948322487,0.19945282519176055,-1.3182411457175676,0.429857390182749,0.5285049852239486,0.1465756160978675,0.7193596211985692,-0.21337800008247138
| 3,120
|
Rac2 gtpase cycle
| 7
| 32
| 2.108524
| 0.034986
|
Q14739,P42167,P50402,Q8TAA9,Q13505,O00459,Q86XL3
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
195,226,290,134,88,339,95
|
339,2136,1588,2427,825,1768,906,226,1286,1192,290,2207,1289,2471,2159,1790,88,2359,551,195,1928,2217,1302,95,134,1626,1680,1491,1264,2339,796,459
|
0.8797499948322487,-0.3599276825042347,-0.09949469747666943,-0.5423276822514903,0.30334561141450944,-0.18463413695639644,0.25170495959874245,1.2254037240919913,0.03888935479482263,0.09305929398318494,1.0344030160862734,-0.38981994606341763,0.03888935479482263,-0.5734566251984043,-0.3599276825042347,-0.18463413695639644,2.4428044126478934,-0.4807050971530273,0.5528233698913807,1.388303199401113,-0.24230752653304063,-0.38981994606341763,0.03888935479482263,2.3644615317552153,1.8959665059951594,-0.09949469747666943,-0.12769463103528156,-0.043624015597528217,0.06605695177290508,-0.45020613666046194,0.3543879449769868,0.6959550565518066
| 3,120
|
Phospholipid biosynthetic process
| 21
| 54
| 2.107342
| 0.035088
|
O95749,Q9NPH0,Q86YN1,Q9BVG9,Q9NPH2,Q96N66,Q8NF37,P14324,Q96S52,P35790,Q6IAN0,Q10713,O15269,Q8TBX8,O00459,Q9NX62,Q92643,Q6UWP7,Q5H8A4,Q969N2,P42356
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
622,6,666,144,543,153,537,402,302,42,553,55,587,219,339,224,640,506,248,385,381
|
2755,339,2548,703,587,2129,2502,1179,1589,764,622,2782,1183,2618,402,2074,1905,42,381,2998,1967,1664,999,55,2766,1541,248,553,506,665,1550,666,537,219,1560,1010,640,385,153,1163,302,1164,2489,1999,144,788,6,543,1817,2776,224,2241,978,2572
|
-0.8636557041179473,0.8797499948322487,-0.6363634842619023,0.4048447144069418,0.5040506253802524,-0.3599276825042347,-0.6048009638951245,0.09305929398318494,-0.09949469747666943,0.3543879449769868,0.4794588708276966,-0.8970706209351134,0.09305929398318494,-0.7001544799726708,0.7657939331769242,-0.33023269302803204,-0.24230752653304063,3.139985047591634,0.8117366781974475,-1.3923270876756626,-0.2714249570573372,-0.12769463103528156,0.19945282519176055,2.9114638007546514,-0.8636557041179473,-0.07147184402573621,1.1626777008156755,0.5528233698913807,0.6249765506068089,0.45472828026538425,-0.07147184402573621,0.45472828026538425,0.5770071775774535,1.2667156015614143,-0.07147184402573621,0.19945282519176055,0.4794588708276966,0.8117366781974475,1.640372274402174,0.11989823952072967,1.012646583383761,0.11989823952072967,-0.5734566251984043,-0.2714249570573372,1.77011455390589,0.3543879449769868,4.588228239206742,0.5770071775774535,-0.18463413695639644,-0.8636557041179473,1.2461096037129336,-0.38981994606341763,0.22565616698772623,-0.6363634842619023
| 3,120
|
Abnormal lung lobation
| 6
| 12
| 2.103256
| 0.035443
|
Q14739,Q92890,P21964,Q969N2,Q9H6U8,Q9UHX1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
195,642,146,385,188,583
|
2196,1382,146,1466,195,871,642,1308,385,188,699,583
|
-0.38981994606341763,-0.015949191785796384,1.733451983355156,-0.043624015597528217,1.388303199401113,0.2776008882438347,0.4794588708276966,0.03888935479482263,0.8117366781974475,1.4280724450354945,0.429857390182749,0.5285049852239486
| 3,120
|
Peptidase activity
| 32
| 111
| 2.097639
| 0.035937
|
Q7Z2K6,P28074,P20618,Q9UIQ6,P42785,O75844,P22695,Q9HB40,Q5JRX3,Q9BYT8,Q4J6C6,P28072,Q9H3G5,P55786,Q10713,O14773,Q8TCT9,P10619,Q16740,Q8IYS1,P09960,Q99436,Q0VDG4,P28070,Q96RU2,O43847,Q9NZ08,P42892,Q96K76,Q92542,P49721,P36551
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
257,378,377,132,7,13,274,32,160,425,39,418,43,54,55,66,325,200,201,84,213,465,93,221,492,220,100,102,371,370,120,127
|
1442,1116,66,473,1955,220,2458,13,1122,1765,860,945,825,2617,213,200,2803,2736,1274,2074,377,274,2904,221,418,378,2585,2622,2512,127,1458,7,102,1913,907,1713,120,1653,1654,1779,1655,1780,1715,2262,54,1090,1135,2746,93,55,2923,2158,2440,2697,2594,201,39,1543,160,2529,1615,3057,2221,257,1863,1551,84,325,878,370,640,1562,642,1743,1563,1994,785,3080,2858,2679,2598,371,1162,492,609,465,524,3066,1426,1311,724,425,646,43,2898,2239,1106,32,1020,792,1021,1940,2798,1434,100,132,2059,2883,1758,564,2546
|
-0.043624015597528217,0.11989823952072967,2.7850237629841788,0.6487648093812882,-0.2714249570573372,1.2461096037129336,-0.5734566251984043,3.9629821531008274,0.11989823952072967,-0.18463413695639644,0.2776008882438347,0.22565616698772623,0.30334561141450944,-0.7001544799726708,1.287222609209894,1.3481584340693418,-0.9307313466100875,-0.8304832815585822,0.03888935479482263,-0.33023269302803204,0.8117366781974475,1.0775884567819758,-1.1028428854778956,1.2461096037129336,0.7426388328088186,0.8117366781974475,-0.6681470252093221,-0.7001544799726708,-0.6048009638951245,1.9662172504490403,-0.043624015597528217,4.524607180078603,2.26843717639146,-0.24230752653304063,0.25170495959874245,-0.1560737352527625,2.0181394542083764,-0.12769463103528156,-0.12769463103528156,-0.18463413695639644,-0.12769463103528156,-0.18463413695639644,-0.1560737352527625,-0.4199119328370344,2.9114638007546514,0.1465756160978675,0.11989823952072967,-0.8304832815585822,2.3644615317552153,2.9114638007546514,-1.1380519309620947,-0.3599276825042347,-0.5423276822514903,-0.764852983812969,-0.6681470252093221,1.3481584340693418,3.1530306783954622,-0.07147184402573621,1.5835213327153648,-0.6048009638951245,-0.09949469747666943,-1.7815233696066426,-0.38981994606341763,1.1415631395121968,-0.21337800008247138,-0.07147184402573621,2.534882233082504,0.9467099920148521,0.2776008882438347,0.8345267182780652,0.4794588708276966,-0.07147184402573621,0.4794588708276966,-0.1560737352527625,-0.07147184402573621,-0.2714249570573372,0.3543879449769868,-2.1178987452790463,-0.9988038179626447,-0.7323887974882097,-0.6681470252093221,0.8345267182780652,0.11989823952072967,0.6487648093812882,0.5040506253802524,0.6724238788270614,0.6010577855594291,-1.904873795283732,-0.015949191785796384,0.03888935479482263,0.4048447144069418,0.7426388328088186,0.4794588708276966,3.139985047591634,-1.0679010003564908,-0.38981994606341763,0.1465756160978675,3.3188565054042503,0.19945282519176055,0.3543879449769868,0.19945282519176055,-0.24230752653304063,-0.8970706209351134,-0.015949191785796384,2.3167291137840786,1.9312396535039034,-0.3007325721587227,-1.033222533253154,-0.1560737352527625,0.5528233698913807,-0.6048009638951245
| 3,120
|
MFS transporter superfamily [IPR036259]
| 6
| 9
| 2.094875
| 0.036182
|
Q6N075,P53985,P41440,Q9NY64,Q99808,Q14728
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
324,104,204,438,242,58
|
2255,204,104,58,576,324,2173,242,438
|
-0.4199119328370344,1.3279431624639007,2.186673620608435,2.8837057870744482,0.5285049852239486,0.9467099920148521,-0.3599276825042347,1.1836886940989366,0.7193596211985692
| 3,120
|
Abnormality of visual evoked potentials
| 8
| 21
| 2.0941
| 0.036251
|
Q9NZJ7,Q9H936,Q15067,Q86YH6,Q9GZY8,O75503,O95140,O60313
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
426,496,300,328,207,115,429,340
|
675,340,115,429,502,1717,1246,1981,300,2368,328,1556,1063,815,207,1167,496,1217,2240,426,2607
|
0.429857390182749,0.8797499948322487,2.086376421063753,0.7193596211985692,0.6249765506068089,-0.1560737352527625,0.06605695177290508,-0.2714249570573372,1.012646583383761,-0.4807050971530273,0.9245051560552161,-0.07147184402573621,0.1730932216945844,0.32894076142978074,1.3279431624639007,0.11989823952072967,0.6487648093812882,0.09305929398318494,-0.38981994606341763,0.7426388328088186,-0.6681470252093221
| 3,120
|
Carbohydrate derivative catabolic process
| 17
| 36
| 2.090481
| 0.036575
|
P36639,Q8N335,Q13126,Q9H773,O60502,P16278,P17900,P15586,Q9NUJ1,Q9BW91,Q9BTY2,P35610,P54802,A8MXV4,P00813,P13051,P49902
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,507,133,167,443,476,268,238,282,308,610,122,276,181,273,285,222
|
181,1441,443,2684,2304,273,1902,1124,898,2070,2618,591,285,238,476,268,2739,2624,3089,122,64,1518,2517,222,276,1665,133,507,1100,1310,610,308,2880,167,282,2545
|
1.4478182777817359,-0.043624015597528217,0.6959550565518066,-0.764852983812969,-0.45020613666046194,1.0775884567819758,-0.24230752653304063,0.11989823952072967,0.25170495959874245,-0.33023269302803204,-0.7001544799726708,0.5040506253802524,1.0560499674593824,1.1836886940989366,0.6487648093812882,1.0990194895203063,-0.8304832815585822,-0.7001544799726708,-2.2504606922272252,2.0009038654063014,2.8276110633492837,-0.07147184402573621,-0.6048009638951245,1.2461096037129336,1.0775884567819758,-0.12769463103528156,1.9136403131944537,0.6249765506068089,0.1465756160978675,0.03888935479482263,0.5040506253802524,0.9907796360095241,-1.033222533253154,1.5258947552631077,1.0775884567819758,-0.6048009638951245
| 3,120
|
Predicted secreted proteins
| 13
| 51
| 2.088812
| 0.036725
|
P84157,Q15165,Q9HB40,O60888,Q9NZ08,Q9UM22,Q92520,P80303,Q8N128,Q08380,P43490,Q02818,Q9UMX5
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
256,1,32,193,100,37,233,12,337,148,89,26,27
|
2340,3099,858,193,619,1585,1447,825,799,984,1389,3071,1232,2142,1274,735,2464,947,1085,89,2906,1524,3106,3074,1847,12,2746,256,26,345,148,659,1724,2592,1,337,2924,3041,233,3019,1103,786,610,2536,2898,849,32,100,37,27,729
|
-0.4807050971530273,-2.671736994716146,0.2776008882438347,1.388303199401113,0.4794588708276966,-0.09949469747666943,-0.043624015597528217,0.30334561141450944,0.32894076142978074,0.19945282519176055,-0.015949191785796384,-1.9889367176870343,0.06605695177290508,-0.3599276825042347,0.03888935479482263,0.37968874363881105,-0.5734566251984043,0.22565616698772623,0.1465756160978675,2.427254953547532,-1.1028428854778956,-0.07147184402573621,-3.1333090781032924,-1.9889367176870343,-0.21337800008247138,4.13921969823986,-0.8304832815585822,1.1415631395121968,3.596283270201957,0.8797499948322487,1.7150000315769534,0.45472828026538425,-0.1560737352527625,-0.6681470252093221,5.344943653484487,0.9021855262027676,-1.1380519309620947,-1.6613267134213334,1.2045970593385245,-1.5057183812598571,0.1465756160978675,0.3543879449769868,0.5040506253802524,-0.6048009638951245,-1.0679010003564908,0.30334561141450944,3.3188565054042503,2.3167291137840786,3.204791775087714,3.5611824108892836,0.4048447144069418
| 3,120
|
Amino acid transmembrane transport
| 8
| 14
| 2.084356
| 0.037128
|
Q9H936,Q9H9B4,Q8TDW0,O75746,O75915,P08195,Q9UJS0,P30825
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
496,526,423,567,621,767,411,126
|
1640,567,621,1768,767,126,1296,1415,423,882,1683,496,526,411
|
-0.12769463103528156,0.5285049852239486,0.4794588708276966,-0.18463413695639644,0.3543879449769868,1.9662172504490403,0.03888935479482263,-0.015949191785796384,0.7426388328088186,0.2776008882438347,-0.12769463103528156,0.6487648093812882,0.6010577855594291,0.7657939331769242
| 3,120
|
Muscle stiffness
| 7
| 18
| 2.07471
| 0.038013
|
Q9NZJ7,P23786,P53985,P00846,Q15392,Q9NW15,P49748
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
426,98,104,9,230,410,344
|
676,2734,9,985,2255,98,344,1523,104,502,2519,2398,230,1355,2224,410,426,2545
|
0.429857390182749,-0.8304832815585822,4.375070750907427,0.19945282519176055,-0.4199119328370344,2.3167291137840786,0.8797499948322487,-0.07147184402573621,2.186673620608435,0.6249765506068089,-0.6048009638951245,-0.5114114008305259,1.2045970593385245,0.011554613903006978,-0.38981994606341763,0.7657939331769242,0.7426388328088186,-0.6048009638951245
| 3,120
|
Transporter activity
| 67
| 167
| 2.064214
| 0.038997
|
Q07820,P24539,P38435,O60830,Q9H9B4,P36543,Q9HD20,P00846,P17900,O43772,P21796,Q93050,Q9UJS0,P08183,Q9NW15,P30536,O95168,Q8WTV0,Q9UBX3,Q9NS69,Q9UDW1,Q9Y6M9,P20674,Q8TDW0,Q9H2D1,Q9P0J0,Q9BXB4,Q9UM00,Q8IXU6,Q9NY64,O96000,Q8NE86,O75964,Q02978,P13073,Q14728,Q7KZN9,Q9Y3B1,O75947,Q6N075,P45880,O95563,O14548,P20020,O95169,P41440,O43808,Q9Y277,Q8TAD4,O75027,Q15388,P00403,Q9Y487,Q9H936,Q9BQT8,P53985,Q8TB61,Q70HW3,P16615,O15118,O14925,Q99808,Q8N4V1,Q9NZD2,Q13423,P30825,P35670
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
503,129,500,3,526,262,136,9,268,15,16,279,411,22,410,25,529,30,157,35,36,565,288,423,40,561,303,441,49,438,178,436,52,432,57,58,185,585,568,324,70,569,199,447,444,204,332,78,208,460,346,225,362,496,101,104,369,110,239,112,113,242,368,252,246,126,255
|
3038,3021,1823,2062,199,940,113,112,3104,675,15,332,2780,3,460,2930,1178,2551,1385,567,568,52,2069,529,444,1587,896,2503,569,178,1077,225,9,3014,1902,862,1332,1229,766,3044,1389,2345,22,767,1507,2968,2711,2255,1079,1335,57,239,268,2584,447,288,1081,769,16,1905,1706,129,1773,1282,2147,25,126,2309,255,711,262,500,1460,204,70,2814,2032,1712,625,3040,1842,3029,910,1780,1342,104,626,2632,1845,2433,2588,3074,2436,1720,2765,432,1469,503,246,2267,58,741,2672,346,1415,745,958,2272,324,1670,1732,719,663,2791,110,185,49,368,2224,1558,436,2173,208,369,423,30,1010,748,279,3048,882,723,929,1426,242,1311,101,1487,303,1166,1213,1066,40,1683,496,526,1432,136,35,410,438,252,561,157,36,673,1572,411,441,1693,78,585,362,2833,2993,1175,565
|
-1.6613267134213334,-1.5441372114598413,-0.21337800008247138,-0.33023269302803204,1.3481584340693418,0.22565616698772623,2.1032619844886535,2.1200791235371135,-2.9227381542310105,0.429857390182749,3.898819192738822,0.9021855262027676,-0.8970706209351134,5.022002691408248,0.6724238788270614,-1.1735319573878251,0.09305929398318494,-0.6363634842619023,-0.015949191785796384,0.5285049852239486,0.5285049852239486,2.925271544766199,-0.33023269302803204,0.5770071775774535,0.6959550565518066,-0.09949469747666943,0.25170495959874245,-0.6048009638951245,0.5285049852239486,1.4674726459409988,0.1465756160978675,1.2254037240919913,4.375070750907427,-1.5057183812598571,-0.24230752653304063,0.2776008882438347,0.011554613903006978,0.06605695177290508,0.3543879449769868,-1.7411148495013815,-0.015949191785796384,-0.4807050971530273,3.744867759885806,0.3543879449769868,-0.07147184402573621,-1.2816373476357799,-0.7975501035896743,-0.4199119328370344,0.1465756160978675,0.011554613903006978,2.897608649302585,1.1836886940989366,1.0990194895203063,-0.6681470252093221,0.6959550565518066,1.0344030160862734,0.1465756160978675,0.3543879449769868,3.844530607020698,-0.24230752653304063,-0.1560737352527625,1.9312396535039034,-0.18463413695639644,0.03888935479482263,-0.3599276825042347,3.607914396820148,1.9662172504490403,-0.45020613666046194,1.1415631395121968,0.4048447144069418,1.120344057573255,0.6249765506068089,-0.043624015597528217,1.3279431624639007,2.683879218936928,-0.9307313466100875,-0.3007325721587227,-0.1560737352527625,0.4794588708276966,-1.6613267134213334,-0.21337800008247138,-1.582874889859472,0.25170495959874245,-0.18463413695639644,0.011554613903006978,2.186673620608435,0.4794588708276966,-0.7001544799726708,-0.21337800008247138,-0.5423276822514903,-0.6681470252093221,-1.9889367176870343,-0.5423276822514903,-0.1560737352527625,-0.8636557041179473,0.7193596211985692,-0.043624015597528217,0.6249765506068089,1.1626777008156755,-0.4199119328370344,2.8837057870744482,0.37968874363881105,-0.7323887974882097,0.8797499948322487,-0.015949191785796384,0.37968874363881105,0.22565616698772623,-0.4199119328370344,0.9467099920148521,-0.12769463103528156,-0.1560737352527625,0.4048447144069418,0.45472828026538425,-0.8970706209351134,2.1368283516262,1.4280724450354945,2.993609575094583,0.8345267182780652,-0.38981994606341763,-0.07147184402573621,0.7193596211985692,-0.3599276825042347,1.3076315066448148,0.8345267182780652,0.7426388328088186,3.4053666094719595,0.19945282519176055,0.37968874363881105,1.0775884567819758,-1.7411148495013815,0.2776008882438347,0.4048447144069418,0.25170495959874245,-0.015949191785796384,1.1836886940989366,0.03888935479482263,2.2845974095289043,-0.043624015597528217,1.012646583383761,0.11989823952072967,0.09305929398318494,0.1730932216945844,3.1530306783954622,-0.12769463103528156,0.6487648093812882,0.6010577855594291,-0.015949191785796384,1.8959665059951594,3.255890605195437,0.7657939331769242,0.7193596211985692,1.1626777008156755,0.5528233698913807,1.621506944075928,3.2176279524756564,0.45472828026538425,-0.07147184402573621,0.7657939331769242,0.7193596211985692,-0.12769463103528156,2.6397490931199465,0.5285049852239486,0.8571974386256007,-0.9307313466100875,-1.3551362796599622,0.11989823952072967,0.5528233698913807
| 3,120
|
Lipid homeostasis
| 10
| 24
| 2.059638
| 0.039433
|
Q96CP7,Q15067,O15118,Q9NQC3,Q5BJF2,Q9BWH2,P35610,O95486,P28340,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
235,300,112,212,53,251,122,217,311,30
|
823,112,762,321,217,1904,311,122,777,3074,3102,300,53,2217,3059,30,235,1622,251,647,212,1173,1373,427
|
0.30334561141450944,2.1200791235371135,0.3543879449769868,0.9467099920148521,1.2667156015614143,-0.24230752653304063,0.9688011263013478,2.0009038654063014,0.3543879449769868,-1.9889367176870343,-2.7705823045491824,1.012646583383761,2.925271544766199,-0.38981994606341763,-1.7815233696066426,3.4053666094719595,1.2045970593385245,-0.09949469747666943,1.1626777008156755,0.4794588708276966,1.3076315066448148,0.11989823952072967,0.011554613903006978,0.7426388328088186
| 3,120
|
Protein transmembrane transporter activity
| 6
| 10
| 2.054314
| 0.039945
|
Q07820,O60830,Q9NS69,P49755,O14925,Q15388
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
503,3,35,625,113,346
|
113,3,2069,1077,625,2588,503,346,35,673
|
2.1032619844886535,5.022002691408248,-0.33023269302803204,0.1465756160978675,0.4794588708276966,-0.6681470252093221,0.6249765506068089,0.8797499948322487,3.255890605195437,0.45472828026538425
| 3,120
|
er
| 25
| 89
| 2.052317
| 0.040139
|
Q06136,Q8NHH9,Q8NC56,Q9Y5M8,Q9BVG9,Q9NPA0,Q96N66,O75845,Q16850,Q14739,O00264,Q9P2W9,Q07065,Q9NQC3,P48449,Q8TBX8,Q9Y487,P51572,O95470,Q15392,Q8N4V1,Q969Q5,O60499,O96005,Q12981
|
Localization
|
OpenCell Localization
|
opencell_localization
|
130,258,138,140,144,409,153,310,65,195,191,73,75,212,85,219,362,354,107,230,368,116,243,244,382
|
191,3022,2548,2885,587,2129,2994,243,617,1503,310,621,1588,107,764,244,1183,2616,765,1643,2140,2256,1455,2024,988,1649,85,2998,625,2935,354,2764,2922,1659,1291,1660,2089,2155,2634,130,75,382,1853,195,920,1296,809,230,1982,1542,65,812,921,1732,2642,1550,368,1556,138,537,258,219,1100,2925,2406,116,785,463,3048,153,1997,1626,144,1213,1315,581,1217,409,212,756,1817,2570,2241,73,441,649,938,362,140
|
1.388303199401113,-1.5441372114598413,-0.6363634842619023,-1.0679010003564908,0.5040506253802524,-0.3599276825042347,-1.3923270876756626,1.1626777008156755,0.4794588708276966,-0.07147184402573621,0.9688011263013478,0.4794588708276966,-0.09949469747666943,2.1535101765609372,0.3543879449769868,1.1626777008156755,0.09305929398318494,-0.7001544799726708,0.3543879449769868,-0.12769463103528156,-0.3599276825042347,-0.4199119328370344,-0.043624015597528217,-0.3007325721587227,0.19945282519176055,-0.12769463103528156,2.489102096014749,-1.3923270876756626,0.4794588708276966,-1.1735319573878251,0.8571974386256007,-0.8636557041179473,-1.1380519309620947,-0.12769463103528156,0.03888935479482263,-0.12769463103528156,-0.33023269302803204,-0.3599276825042347,-0.7001544799726708,1.9312396535039034,2.669222272429499,0.8117366781974475,-0.21337800008247138,1.388303199401113,0.25170495959874245,0.03888935479482263,0.32894076142978074,1.2045970593385245,-0.2714249570573372,-0.07147184402573621,2.8134649963657146,0.32894076142978074,0.25170495959874245,-0.1560737352527625,-0.7001544799726708,-0.07147184402573621,0.8345267182780652,-0.07147184402573621,1.8782176443063971,0.5770071775774535,1.1415631395121968,1.2667156015614143,0.1465756160978675,-1.1380519309620947,-0.5114114008305259,2.086376421063753,0.3543879449769868,0.6724238788270614,-1.7411148495013815,1.640372274402174,-0.2714249570573372,-0.09949469747666943,1.77011455390589,0.09305929398318494,0.03888935479482263,0.5285049852239486,0.09305929398318494,0.7657939331769242,1.3076315066448148,0.37968874363881105,-0.18463413695639644,-0.6363634842619023,-0.38981994606341763,2.683879218936928,0.7193596211985692,0.4794588708276966,0.25170495959874245,0.8571974386256007,1.8603931337258688
| 3,120
|
Vacuole organization
| 9
| 55
| 2.044608
| 0.040894
|
Q9UQN3,O14773,P11117,Q14108,P16615,P50897,O75503,Q9Y3E7,Q8TBX8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
162,66,97,105,239,48,115,253,219
|
1497,66,2067,1503,115,1271,429,589,1902,1389,2618,1593,97,239,768,680,908,48,2207,276,1193,869,2091,1975,105,1981,601,1004,2217,1552,2173,219,2406,1159,3048,2940,1482,790,373,2116,1167,1018,2119,1170,2188,563,1111,2057,1025,162,1887,1031,253,1758,2294
|
-0.07147184402573621,2.7850237629841788,-0.33023269302803204,-0.07147184402573621,2.086376421063753,0.03888935479482263,0.7193596211985692,0.5040506253802524,-0.24230752653304063,-0.015949191785796384,-0.7001544799726708,-0.09949469747666943,2.3167291137840786,1.1836886940989366,0.3543879449769868,0.429857390182749,0.25170495959874245,2.993609575094583,-0.38981994606341763,1.0775884567819758,0.09305929398318494,0.2776008882438347,-0.33023269302803204,-0.2714249570573372,2.186673620608435,-0.2714249570573372,0.5040506253802524,0.19945282519176055,-0.38981994606341763,-0.07147184402573621,-0.3599276825042347,1.2667156015614143,-0.5114114008305259,0.11989823952072967,-1.7411148495013815,-1.1735319573878251,-0.043624015597528217,0.3543879449769868,0.8345267182780652,-0.33023269302803204,0.11989823952072967,0.19945282519176055,-0.33023269302803204,0.11989823952072967,-0.3599276825042347,0.5528233698913807,0.1465756160978675,-0.3007325721587227,0.19945282519176055,1.5835213327153648,-0.21337800008247138,0.19945282519176055,1.1626777008156755,-0.1560737352527625,-0.4199119328370344
| 3,120
|
O acyltransferase activity
| 6
| 12
| 2.040689
| 0.041282
|
P23786,Q8NCC3,Q6UWP7,Q96N66,P50416,P35610
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
98,11,506,153,403,122
|
703,98,2203,122,403,506,1550,11,537,153,2489,2776
|
0.4048447144069418,2.3167291137840786,-0.38981994606341763,2.0009038654063014,0.7657939331769242,0.6249765506068089,-0.07147184402573621,4.159435423734304,0.5770071775774535,1.640372274402174,-0.5734566251984043,-0.8636557041179473
| 3,120
|
Glycoprotein metabolic process
| 14
| 58
| 2.04039
| 0.041312
|
Q96JB2,Q99805,O60476,O43505,Q96L58,Q9H0U4,O15118,Q7LGA3,Q8NCH0,Q10472,P35610,Q9BT22,Q9H6U8,Q9NX62
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,131,192,141,175,373,112,17,117,214,122,319,188,224
|
2709,112,2249,141,192,443,858,1639,2502,2995,617,2581,765,1643,2804,3089,2080,122,988,1649,2089,2091,2397,2093,1469,1194,2526,717,214,838,1246,1144,2560,1004,720,17,2701,666,117,1100,370,96,175,3066,1164,131,319,1366,1066,373,2117,694,188,849,224,1882,1261,2572
|
-0.7975501035896743,2.1200791235371135,-0.4199119328370344,1.8424923729445961,1.388303199401113,0.6959550565518066,0.2776008882438347,-0.12769463103528156,-0.6048009638951245,-1.3923270876756626,0.4794588708276966,-0.6681470252093221,0.3543879449769868,-0.12769463103528156,-0.9307313466100875,-2.2504606922272252,-0.33023269302803204,2.0009038654063014,0.19945282519176055,-0.12769463103528156,-0.33023269302803204,-0.33023269302803204,-0.5114114008305259,-0.33023269302803204,-0.043624015597528217,0.09305929398318494,-0.6048009638951245,0.4048447144069418,1.287222609209894,0.30334561141450944,0.06605695177290508,0.11989823952072967,-0.6363634842619023,0.19945282519176055,0.4048447144069418,3.811591163952668,-0.764852983812969,0.45472828026538425,2.069421914151396,0.1465756160978675,0.8345267182780652,2.3644615317552153,1.487036333627781,-1.904873795283732,0.11989823952072967,1.9312396535039034,0.9688011263013478,0.011554613903006978,0.1730932216945844,0.8345267182780652,-0.33023269302803204,0.429857390182749,1.4280724450354945,0.30334561141450944,1.2461096037129336,-0.21337800008247138,0.06605695177290508,-0.6363634842619023
| 3,120
|
Regulation of lipid biosynthetic process
| 10
| 26
| 2.038479
| 0.041502
|
P49748,Q13510,P16435,Q9UBM7,P11802,Q12770,O75477,P30536,Q8NF37,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
344,71,327,699,549,600,588,25,537,30
|
2012,588,1179,1899,1589,799,862,549,327,2074,25,2666,680,344,2432,1665,600,71,1730,537,30,1622,1164,699,2572,2337
|
-0.3007325721587227,0.5040506253802524,0.09305929398318494,-0.24230752653304063,-0.09949469747666943,0.32894076142978074,0.2776008882438347,0.5528233698913807,0.9245051560552161,-0.33023269302803204,3.607914396820148,-0.7323887974882097,0.429857390182749,0.8797499948322487,-0.5423276822514903,-0.12769463103528156,0.5040506253802524,2.683879218936928,-0.1560737352527625,0.5770071775774535,3.4053666094719595,-0.09949469747666943,0.11989823952072967,0.429857390182749,-0.6363634842619023,-0.45020613666046194
| 3,120
|
Phosphatidylinositol metabolic process
| 11
| 22
| 2.02973
| 0.042384
|
Q5H8A4,Q96S52,Q6UWP7,Q92643,Q969N2,Q10713,Q9NX62,Q96N66,Q8TBX8,O00459,P42356
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
248,302,506,640,385,55,224,153,219,339,381
|
2755,339,2548,2502,2782,1183,1594,381,999,55,248,506,665,219,640,385,153,1163,302,1999,1817,224
|
-0.8636557041179473,0.8797499948322487,-0.6363634842619023,-0.6048009638951245,-0.8970706209351134,0.09305929398318494,-0.09949469747666943,0.8117366781974475,0.19945282519176055,2.9114638007546514,1.1626777008156755,0.6249765506068089,0.45472828026538425,1.2667156015614143,0.4794588708276966,0.8117366781974475,1.640372274402174,0.11989823952072967,1.012646583383761,-0.2714249570573372,-0.18463413695639644,1.2461096037129336
| 3,120
|
Subsets and Splits
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